<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
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<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2E5</accession>
    <name>A0A8K1C2E5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2E5"/>
    <dbReference type="OrthoDB" id="10251642at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000005">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980">
        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980:SF15">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0158">Chromosome</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="10"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="290" mass="32753" checksum="A479CD102858BF71" modified="2022-08-03" version="1">MELKTLEEIEGMHRAGAFVSKVFRNRLVADMETIIDEDRTVSHEAIAAAVEEVFDDPRKLWDQSEPGDVRVVYPPIVQSGGKYDLKPGVQSNSDALKYDVIICSLGAELKGYSAAIARTFFIDPAESMKESYELLREAHDLCAKELRPGKTIATVVETIYAFIQSRDTRLFGKLTKNLGFGIGSEFSESRYPLSVENTTVVAEGMAFNLAFGFQDIPIEQWKIDNYTIYMADTVMVMENETTYVTNASKLWDKVNYTIEDDVRISDQSSPAMTIERFWAISSYRNPQDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2G9</accession>
    <name>A0A8K1C2G9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2G9"/>
    <dbReference type="OrthoDB" id="19174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="125" mass="13490" checksum="9FC7BA570A3C419C" modified="2022-08-03" version="1">MKIDGADIHARNADGWTPLTMCVRWSGRPAAPLDALAAVYELMKLGAVYEDSPDNCPAMSPDAKRTRPGSTDELISAFELGASIPICIQQWTVEQQAGKPLTRIPHEVAGNGVKAVQSYLEQIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3D5</accession>
    <name>A0A8K1C3D5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3D5"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="132"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="279"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="8">
        <location>
            <begin position="653"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="889" mass="100015" checksum="ECA9FD83E47D03C5" modified="2022-08-03" version="1">MMPSASMSMQLTPPLSPVRRGARGRAGSANMVTSARDLLAAKPRRASDERKLQLEEATSDVSTVTTSSSSTSELTAFVASVEAQWVRRKSQWLSHFKSGGASDDEEDGENDANAENDAENKAAKRKREAHEKDLNSKCHVCNVALRLYRLRHRCRNCGMAVCGVHSKNQVPLPHLGIMKEVRVCDLCTRQLVQRRAGYRSPRTHKKARASSSMNEEELLMAGVAEPSSEPRASRASLSTLPLSPHSPHPVESKESELLGSTSGVLYSCLLEEQANIVDEILYLGTLTMGGRALASRHLNGNVAIWKDRWFMLTSAEMLCFKATTDDDKTGGASLAALGELRSSVHLTDILHIELNDQYPRILTVIRSDGRVFRVRAKTPEQCQEIMAAIKNAQQLFQDAMHRLQRGVQPEDFSISCVTIQHESSLPEQVVASSPLLNEKIQVEMYGSSVLRFYVNGPDTNGVAQYSCQTILLSLSGGLTNGSGQLITCEADPLRAGSWDSKLLRVSLRPSPVSSTFREAMSKQNRLFWTVAVGLVSVGLYAQHRQLPPLEVVVWLLIWMMTLTRFHDPLMLLVTTQRFQRAKRFCVECVEIAHNKKKVASDDDDLAPHDEYVDPRFIEGCNGDIEDAKRRYAETMQWRREKDIDNLLLRSQPHFSAMKASYTHFIHKKDRTGHLVSFEHFGYTKKMREEFLSRGVTEEEAIMHQVFLQEFLWNVVDPRVYPQGTQIKVFDIKGVSMADVSGEVYNFMKNLGTTVAEYNPERMFHIFIVNPPSWFNLIWKVVSPSINPKTRDRVHVVRGPKEVTKALLQFIDEESLPIEYGGKCQCPGGCFTNSPEETDLRNYVESYLNTMEEGDPRIAEALEALKEKYHRQLLPYNKEASSHGHDANTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3N0</accession>
    <name>A0A8K1C3N0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Poli38472_008482</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="19">Forms DNA polymerase zeta with REV7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000007">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="24">
        <location>
            <begin position="66"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="820"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="1116"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="396"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="580"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="TMW55834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1618" mass="182842" checksum="48BB04783224874D" modified="2022-08-03" version="1">MTDDEEEEEFCMETVVVDYYMSAPLPDDALYKLPVSPCYRLARQVPVMRVFGATPAGQKACLHIHGLFPYFYFRAENDPVFDDVEQLKKLLPRIAMELEKANELKQKQAKKTTNEESTSTQGNGQRQGRSRRSTTSKLVAKLLIVQGMPFYGYHDTPRLFVQIFLYNPRAVASTVQLLESGCIAERRFQPYEAHVPFLLQVFADYHIEGMNHIHLSHVKFRAPLPAVQDHLKRDCVEGEQLPVYLRSNVPSSKIHGDVAMFAQVVKGRSVRVPGAPVQWFDRHSSSVLEVDVAAECIMNPRLFTKLQKSLVGTSELRSVPSLAALWEEERLRRIQNGEQGTPEFSLSVERKMDRTPEPTGLSAAQSASSLLSQSFFQQKMQDAVATIMEQFEKEKLEQSHSSIDEVSREETRTQFSQQCSSNEIAHSRSTIMTESEYSFSQNQLYDGRMHADDSATDEAEEQKEDEDIVNLLLAMQQEPRSNLASDLTVNTRPGYHGEDAFTDDEIDRDEENEIGMRAEELEDIGDILASQRLFEDELTERTTSNRGGKADRERETKNSWWNVGDNEQLSASSGVLDIGSPRLEWSEGQQHRKRQESSLKRKKRLQYDSEQGEGDEEDEEVEYVLDIEDLLPPQPPPVRMRRQREEEESVPLDPSLLSPTPNFRRIVRKIPKPPSLQEQVKGRPKVWLFDPPPPSMSDLLVSSRLLGVGEMEHQAAYYSNADDIPEKPLVFGGKKFEFTPTDLTHIPRFDTLQSRAMRNGKNELPSWSTLDSLKSHQPPHLFATVNKIQRVRIPATSPPTYGDVEAWLIEEKGTISVDYQRRTKKPRHDPLTTSLEARKLHSSATSSNLTILSLEIHANSRSNLLPDPHRDRVELIAYAVEAQEGPTAEKTKERGIIIVKSTEAQPEGYGGMGPMGFCVDNSELCVAIVESEHELLTRLEELVHRWDPDFLVGFEVQKESIGYLVDRSSQLKMNLVQMMSRLPTTQVDARNTSALLGPDEIEEGNGEVSIGTTWGVTKASGLWVHGRQILNLWRLARSEIKLSRYAWEDVLRAVMKREFPVYSAEQLTTWYVAGGQLRWKVVRYVLDKATLNLKLLSRMQLVTRTSEMARLFGMDFYSVLSRGSQYRVESVMLRVTKRHNYIMVSPNRTQVARQAPMECIPLVMEPLSTFYSDPVVVLDFQSLYPSLVIGYNLCYSTLYGRLKSGLKPELEAELGVVDFTPSSSGLLQDRDNLIISPSGTLYSSKVNRLGVLPVILDEILATRIMVKNAMKKAKERGQERLEKVLNARQLALKLLANVTYGYTAAGFSGRMPCAQLADSIVQSGRCTLEAAVRLVEGNREWNAKIVYGDTDSLFVLLRGRSKQQAFRIGQEIADVVTASNPKPVTLKLEKVYMGSILVSKKRYVGLKFENPNQAVGAIESKGIEIVRRDSCGVVQKSMQSCLELLFATSDLSQVRQALEQYWTRMLEDSLPMKDFIFAKEVRLGTYARGSAPPAALVSAKAMAKDPRAEPRYAERVQYVVINGPPGARLVDLVVSPFDLTNRSKRRSINYQYYIHKQIIPSLERLFLLMGANASHGCVIGVQMTPSAVSLYCKSSQQEEIKSWKYYGWCARLVATAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4L7</accession>
    <name>A0A8K1C4L7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4L7"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="6">
        <location>
            <begin position="463"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="574"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="595"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="643" mass="70514" checksum="72A881FD331240E7" modified="2022-08-03" version="1">MQVLSATHEYFAAVSEDNRLKVWDVSSGAIEHDLKERDHLNYKYTCITWTQHSPLTKAGSKRAKTSSQGLIALGTSTGVIVIWDLRKGEVVQRLSSDKEGHNGAINDVAFNSQGNLLYSCSSDKNVLEWNVKDGSVARKFRCGSEGAQKVAVSPEDEILAVGGTAIRTFDLSSGKKARKLVAGLSSAVNQLRFSQCKRYLFSATIGGRFVNMYDLSNAENDEPVVNFSMPSSSASLFVRTKSAKKKADVLLGAVSTTGSLFVWNHKYKVSSAKTTKPVAPDAKSGATAGVLVAELGQDENEQSQITVVRGSTAKPAFEKLSLLDDQQQLVSELAFAPISEHLLLGDKESAQKKQKVLAEAAEKEKTHIPALAERSGLAKAKDVVDASGEFDELRDEDEDEEDGEGALSLAERVEALRERVENDLAAEMVRVDADATANRVGPSERPDASSLSSLLEQALQSKDNAMLEYCLRTRDAKVIANTIKRVSSVKVLELLDILVLKFEKSPGRCARLCPWIRSILLHHTAYLMTQPDLVQSLSALYQILENRLKVHDALQKLSGRLSLVIGQIHEASYQQQTGEGDAEGDAPRAKIVYKEDDETDQQEDEEDDDEEEEDDEDAVLENGVDDDDDDDDVDMDDDDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4M9</accession>
    <name>A0A8K1C4M9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4M9"/>
    <dbReference type="OrthoDB" id="162570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="31434" checksum="992F008FE9F076C1" modified="2022-08-03" version="1">MDAAHADHGIHAHRPPVAVVAPRLRYKHNLAAKLDAVTKNSLWGRRKVVLNDDKNALKTALRNGSPRHASVANPIMSAPESSRSSGGYSSNKELSASELEIKVMTAFRQIVRIWRERRRKAEAKAVSMMNGNSNGAATNKFRRDLSAHSSNVVGIVSRRLIREVPALKFFDDETEINPVTVAPTTTNRASVLVPNKRTSTTVPAPPPQRPLSPSALVPVMGTTPQAERARPRGVCYTLDAFGCRKIKMRSSTSTPSRRENKSSDHNGKSEELTLEKAMRRSLHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C540</accession>
    <name>A0A8K1C540_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C540"/>
    <dbReference type="OrthoDB" id="340962at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="121"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="403" mass="45982" checksum="6F0ADB9973CB78CC" modified="2022-08-03" version="1">MAYLQTSTHFNNWVFQADELARVDRLRVLKAKKALRLEREASAAAAASATTEGSASANNGLKTTRKARSFAALVPASSTASRDIYDWNDEIDMPLEQAEEAEEKDGLKLTPLIEYLSVEQERLVREYYESKVQESCSQLFRTSDKVKCSAVMLFKRFYLSNSVMEFHPKYIVPTAIYVAGKVEEQYINVDTIADQLKVDHKHVIDHEMILLEGVRFQLIMYHPFRALLGFVDDFRGFSKAQGRDLPLEALQKLHANSCVVVNELLLTELPLVHYPAYLALAALCHVAEELERETPALKVTKADALEYIKRSKFAQGQDVAKVYGTLETITQRHQAFKTQKAHEQTPGEAEKLAKQIKKLYKKLKKFHVEDGDGKKDDKESKKRKSDDKKDEKKKSKKHKKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5D1</accession>
    <name>A0A8K1C5D1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5D1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="758" mass="84901" checksum="C85D4D6A06C3D278" modified="2022-08-03" version="1">MTDDTSFETLLQPLWDVFPRGELQIEHDATKSGLRKELYAFRISMASRAARNKTEWMRQLAAIELLLLASLVKPRAFVRLTRQHLRLAENYAPGSTSSSSPICWSHVSDTHVIPCRLVIDYDGYELLETTPVHFGGLGSLASQHEEPVRMYESSDQPQSPLDALALLLTLKPRASNGSDMEEIREKLLTMACTPSVRQQWEAMTIPVCIRLRGLENEELEAAVKHLSTLQQARPCGSGQSVLHQHDERENPFHAESVDLFCRDHCGEDRLPHPMVGWFKELHAVGLALRWIYFYKFPRDRKAVTNITRAITGAPSPAFVGDTIYSHGARVVAPEFTSTEDHVSFYSGLMHSRGVEHMSLSGIYNWHWFLYALFHASATHSVRSLEIVNVELFTEDVRRIHGLLQLPQPLDALVYQLSGTVETPSTPKTGSFVELKEGAPVYFDRHPSNADECVAVSSTAIPLKVSDSEQDKISIILPCYGECWANASDIVLVRPDPFESDPEKQWKLKTHGITHLKFYFGEADEEQSASMFRLLELIGEPVTSLAMDLPGLSDDEVFQLDNIWSFCPNLTELSITGAYLPSLDAFVQAYESGTCRLTSLEVVGCDVEDQDSVAVFAEALADPSTALSRTLKHLRISLAKKYGGGEGMIDEEVAELFLSALKTNQRLSFFELQLSEDTLEMYEHEVEAQNGLYLDNGCTPLSTRARRAFLSVVKCGQTKPQETSLACLDAHVLSRILYMAAEPERRAVVITERSHFYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5G4</accession>
    <name>A0A8K1C5G4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006658</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5G4"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="563"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="948"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="450"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1100"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1101"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1115"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1137"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1161" mass="131999" checksum="30832D90F7772E67" modified="2022-08-03" version="1">MTARWQDEYERHWKPFTTDALCLRFGHDVDNYHVTAGDLQQLRDVLHALGSTYDPLAQRPRRPLPFKPKPLRRRRRSSVRFHSPLVTHENPPEATQENESESTQEYGGVPPTQPFDISMDGDESDDDDEDDDDDQGLGGGMDSEESYVYHTPEAKMRPSRASTSSVQSVDFQSRRQSMQSVSSTSTFPVFTSQDLRTSMDLTRRESASQTLRRRLKSVSPIGPGRLRFSVGSELDSSRRLSTSSQQETCDAPFETQTQAIGVSEGVSPFGPPASAKRLKTMKLHSSAQKEVEVSGIPSTLDEEEAVGIVDLDVSMQSMHLSEDNASFQDETPQKEEDDDMYQHEDERRVTMALDFDGVSDNEEEEEAVTMPNRWFRSEPPMENQADAHPAPETDQPMAQDQEVSEREQDESTRLDDNEVVVMESESPPRPLKDNIRDVMLRDRLCSAGLTFSDEEQKDEVQDTSLPQPDPFASSSSSSSSSLGPRFQTKMPLVVSSRFSNVDERRRQRRRKLKDKLVELSQPLGMPEFRVDLPSYQREAVDWMHARERDHIVSDCNNRKQRTARLTASIRGGILADEMGLGKTVCCIALICESSRRIRQELQESLSDKQETNSTTDGTVPRLKPPTLIITPLSILSQWEQEIRAKTNLSVITYQGHSRKQIQNIMDFMGVDIVLSTYDTLRLRECKVRPGKEWPDDGDEDEENDEDVGNFMDKLNDSRQWHTPSRRLSNSKKSFVGCKLHQLTWYRVILDESHLITNSSCARAQSAFTLRSKRRWCVTGTPIQNSGKDLSSLLSFLGLKSLPVDVKYQEILEKVMLRRFKSTVDAISNEPIVNLPPKEEVLVSLDFETDLEKAYYLLLHRSTKRQVLQYLHSSRRKRGHESAPFMHVFELLLRLRQCCDSHTLVTQDPLQEVRGNARLLAEIGTLSRQDAALVEQLQDVRQLPVFSTKLTALLHELEQVKANREQALVISQWTSYLDLIADAMHHHTERGSEALTVARLDGRMNAKERETAIAAFQQERRVDVLLVSLRTGGLGLNLTAASHVFIMEPSWNPSIENQAVDRAHRVGQTRRVRVVRFIMKNTIEERVVALQKKKKEIAATTLGDSTRNAGPNGSGRETRLSRDELRLLFTQGDVETHENEDEYDEESDEAGSVEEQIWEAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5I0</accession>
    <name>A0A8K1C5I0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002827</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5I0"/>
    <dbReference type="OrthoDB" id="10261027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="289"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="619" mass="70113" checksum="03AD3CC5372BA290" modified="2022-08-03" version="1">MSDKMWFDVWEYVQWTTLVLACLSSMFLLVHSISFHRLKRRMADFLLCVIGLSDFCFSALEALKQHVHLTYSGVYETDRTDAEVTAVELVASTISRFAFFMSLYWIANLSMLMRLGKIEDLHIRRNFLFSVFLALVYGAMHASLQAMDNVFAYAMNACILFMIQVAVLGTIVSNLHYVRWHSRMNENSHGRNVILRLTGYCICAALFTLPYSLVLMVYQRHVPLGVITETFNYFLPIANAILFGTGITCCWGAREGDLPEKLPPTKASKSSERTYSPSTVGPLTEMVTESPVVKVGEGSSAIVYRTQWLGITVAMKCIRLQGVSEDMEDLYLTHMSEIQTTFCDEAALAAQLRHPNITLFIKLGTYKGSMCLVNEYCSRGSLRDCLKANPLMEWSTKVRLAFEAAKGLAFMHNRDPIYLHRDLKASNILVTEDWTAKISDFGISRIATDYTLTTRRKAAFPIDSKQNEETRVLTTFAGTWRWNAPEIMANPNECHFNRATDIYSFGMALWEILTNGATPFGDVSFDHQVRTLVSNGERPKVPPVYVSRAPPEFVEIIKACWDQRPENRPTAQDVMLRLGSLSYSLYNSTEPSTRQTSRAVFSDNYYQALDSARSCVIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Y1</accession>
    <name>A0A8K1C6Y1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003483</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Y1"/>
    <dbReference type="OrthoDB" id="155729at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425059" description="subtilisin" evidence="10">
        <location>
            <begin position="23"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="177"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="523" mass="55786" checksum="76740BE42D0DA7D1" modified="2022-08-03" version="1">MNLRLTLVAAAAVAATTVSVEAAPRVHHGVHRQLREQGKANIVVTMKTKPTEALASLESTSFASRGDKISHMVNKLETLASESQREIDALLSQESTVSLFEAEHKSWALNARLFKGASAELIDKLAGLADVAEIRMEEVYQLHDEPAKIVESTEANKIEWGVDRIGATKVWADGTFGAGVVVANIDTGVRYTHEIVKDSFRSDYNWYDPDFQTDKPYDNNGHGTHTMGTIAGAKGFGVAPGAKWIACLGCPSACPEFNLVKCGEFMTCPTDTKGQNKDCSKAPHVINNSWGGSGGRPYYQPVVDAWHQAGIIPVFSQGNSGPECGTAGSPGDYANVIGVGATASNETLARFSSKGPAKSGLLKPDISAPGRYILSSFNGSDTQYANISGTSMAAPHVTGAIALILSANSSLKYNDVRTLLTSTTDQATLLPTNYTCDNTPDTVWPNNQYGHGRLNVFNAYQGFRPSPAPTTPAPTTSAPTPAPTPAPSTPAPGFCAKIKTKGVCQFWFFCNWDSAVDSCLPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7I8</accession>
    <name>A0A8K1C7I8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013332</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7I8"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000025">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="56965" checksum="13DF42644E23A10D" modified="2022-08-03" version="1">MQQAVLDPESQVEKGENARMASFVGAIAIADMVKTTLGPKGMDKILQSMGGPDKNISVTNDGATILRSVYVDNAAAKVLVDIAKTQDEEVGDGTTSVAVLCGELLREAEKLIDQRIHPQTIIEGWRIALTTAHDALQQSAQDHSSDPEKFREDLLNIARTTLSSKLLTQEKNHFAELAVNAVLRLKGSNNLDHIQIIKKAGGSLKDSYLEEGFILDKKIGVGQPKRIENARILVANTGMDTDKIKIYGARVKVDSMDKVAAIEDAEKAKMKAKVEKIAAFGVNCFVNRQLIYNYPEQIFTEKGIMAIEHADFDGIERLAAVTGGEIASTFDRPDEVSIGECKLIEEIIIGEDRLIRFSGVKTGNACSVVLRGASSHLLEEAERSLHDALAVLSQTVKHSQTVMGGGCTEVLMAQAIDAKAPSIPGKKALAMEAFARALRQLPSIIADNGGYDSSELVTQLRAAHHNGQTTAGLDMTNGTIGDMEQLGIREAYKSKKQVLFSAAEAAEMILRVDDIIKCAPRKRDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7X1</accession>
    <name>A0A8K1C7X1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000141">
        <property type="protein sequence ID" value="TMW57642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7X1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460673" evidence="1">
        <location>
            <begin position="19"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="344" mass="38240" checksum="AA64CB6ECF3E33F2" modified="2022-08-03" version="1">MLQGALIALLALLESAEAGLSVPKPTDVNRDGSLAQQIALSEVQVLIANSTNYGALFSSAISEQLSAGKLTSLDAISGIYDAVPKGLFRPMSTDISDATFGQERITTKAMKLHQVRPNEYRSSRAFALTDAQLSKLCGRGATWNNIRRQKQLYVEDYHDIAQWNDPEAPENTVNVFVQRYIDVYYKNDQAIKSDFELQNWARDWARDCALVPHLKEFPSTFTAKAQLQRLLTRLIYLSAPALCTGSAARKGVPVNLMDFVAPPVTLPVILGDLSAFVRPVAPVHSWLGAYAVAPFSQEAALQPAIADLQMSLRTIDTFIQKQERGQKWPYEYLRPSTLPYFSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9G9</accession>
    <name>A0A8K1C9G9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125484at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032171">
        <property type="entry name" value="COR-A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16095">
        <property type="entry name" value="COR-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="168"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="COR" evidence="4">
        <location>
            <begin position="630"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1455" mass="163196" checksum="9D7AF62896FC89DF" modified="2022-08-03" version="1">MRQQSLHDAVKRGDIATVNRLLQDGVEIDALEPYIGRTALHYAAMKNEVEIAKTLLSRQASVHAKSVRNALTPLHFAADKDSRNAAVFLVENGADVNAPDKNGRTPLHSAASSDSSEVAKFLLENGAEVDAVNKLGETPLHYSATSNRGVVADVLLKKGASVNVKSKRGRTPLHEAAAQCRGRLVRLLLRNGADVTSLDEDGNSPLRCLAIRALGDNRVLDEELRMLYRLMSAGSPWTDEDDEEIRKQAREKKREKQVSAFLAAIRSWVKQRHDGMKKLTRLPLEVYKRGGPDVRVYFTFAVPHAIRRKTLEEEGKADGLSSESSRQLVDDASVYRKKLCVVGPTFSGKSGLLRAMTKQKRVTMRSSEDQDVGIEAFSWKFESSSSEDREKRQYEVTILDFAGRDDYQSIHSLFYSKHSVYAICIDLKEYADALEEAEVEVAASRSSQMDGFVEKHVFRWVRVICAREPESEFVFIGTKADLINHDAQLIEKISTDVMARVERKREQAAQELSRMVSTLRKSLKNDVEEESDMKTHQRILALEELQTKAVRFLSSELLVVSATSLHGLDKALTQLEQCIIESDTSFLIPEMYQKVEDFVLKQVQASTAEKTMTAQVKSAFQNITDLKEAIEKELTISGEESTAILHVLHDLGDIMWFDEVDGELAEVVFLNPALVIDFIRQVINRKLVDDPDKEGKEVEARLQSLYEAVRKEGRVAHELLCELDMWYDVHDDQRILQLKQLLFQFQLAYPAGNNTIEWNSDLIVPMYWKKRMTGDDTEETSSTDLAIALPESVCWEYDFHRHLPDNIFEKLGVQSYSSHYSSNRVFTRDSFETHAKGKYVARVAKKVRDESASDSGSEDWTILSIEVKAAKREEAWQQLVWYSMNLERLLEDYPGLWVNRYTLGREGKRYDVDQLMVELQQQKDLHLDDDVLPPSMEWYITEAWTGRDNDTSAISRGRAPTTFLVSDLEARFQTLLENQFQNVYEKIDKSTDKLTKQLAEVGNRRDYPSLWTLEYRPESDGTVSTASYIVKIRSHLSGVCYHEPIVVTVKTGFFDKYGIQIRNGISLLASVTLGDFLSPVVDGITNELETAAELHSLVQGLDLPSTGPLDMENDRTMSPDSSIVLLREILTAYDDKFDPLRMSSLCGLECAIIVESGEHIWVHRTEIEGRTDIIFRHDYTSSTAGVGDNVQQITAAGSFKAIPQIEGQPSSKIYEIPRIEAEPEAEAEAGWTIPPAEQIERLPSIHVKQSTTVIARQPSRQTSSVALKSAIPSGSSGSLKSIASQRSMGGCRSTLVTLDPLLSIRIIGLQDQNDGRPTTSVGSVCKWRLMDEQGRLGNSGSTQPLASEEAARGWSTQAFLVDVPNGVESLLGCTLVYRVQAKPRRSWTDWFCGCCRRTESEEIGMGSFTFGDSALADLESGRWYEYATTVLHGKGDLAGALVFHLRVETNGEADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9W0</accession>
    <name>A0A8K1C9W0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007196</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9W0"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="3">
        <location>
            <begin position="44"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="39538" checksum="0A995AC264B17450" modified="2022-08-03" version="1">MTTSKYGYALNYDWKHPWPRAPIPVNEEGRLAELERYNIVDSEPDEKFDKLCRIACKEMKCPIAAVSFVDKQRQWFKANSGLTQKQIPRDVALCAHTIMHPKRALIVEDTSLDERFKSNPLVTRASAVRFYAGVPITTPNGFCIGSVFVFDVKSHENVDARILHKIAAKVLKYMDERLKPGSTRPSVNPADHPTIERKSSADLTADKPAPATAPVPRPAPVQTPGETALREQQAPTPAPVAAPVKPTPAPVVAATPVPAPATAVAAPAPVPAPEAAEGALVQAAPATSTALEVGGQQQGGLGNMGSMLMNLLARTTETQQQLAAQQGVMFETLGNHSSQLDTLNQSMSKLEEKIEAVRLKRQAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAF6</accession>
    <name>A0A8K1CAF6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAF6"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462172" evidence="2">
        <location>
            <begin position="25"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="746" mass="84370" checksum="CFA9FE07A70B868C" modified="2022-08-03" version="1">MPPLGKRALSVRKLILFVLNVASTALTLLTGLRENPVITTIGGRYDAIRSRLRDGLLSYDIVRDDVVQIDKLPDLVEAGDSYRFISAPRRSPANLAEDRSTCRRVNSMNVTVMTVNYDDFWGYGPRRTQVFLFSISAKRCGVLNLKPKWVDNCMKDRQGNATQCHEYILENFDALSKRQVIQAGAEKDFGEVGVPFLKCMGRPERSFVFNADLMVQQSFWAGGSYHIEIQTSDCRAKPLIRDADWLWGLFQVEQVDQAANVLLALPHTGWFAEIVTFLFGIVSITMIGVGIVAIFMQSRAVTYLPAALRKTREHKVAKVLAPFMPISTLLAESENSIITFKGSIIMASDIWMNHWLYITMSVLDAVVNIRTTYIVMNMGTWMLGKKGNFENFIFFCSALTRITWLMCFIHTLIRLFFKFVLRSLRAMKVMKVVVRDRIEWYMDATALFMSYKIYNLLLCVILYLMLKYHGGTTFMVGQPVKKQGNYGGTVSIAQFWQNEIICDFTVILAMLTASGLALSTILLLSKYRYIANNGVIRLLQQRYVIVGWDALTAAQILGMDPYDPDLADKNVGLTNCSIGSLLQMLYSSGPSGWVKLAGDYLFVDGGFSREPIIFRYPVKRAITMGLCQGNSRFSMYQKDVASNGTELASALTTQRITNVSPRKQTIDEEHSKTIEMDRTSLFDRRLRICTEGYVGKTLLVDISEPGSITKNLETGRREYVVRDALSYMTILDIKPLLNNEKKLNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAN4</accession>
    <name>A0A8K1CAN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Pyruvate kinase</fullName>
            <ecNumber evidence="5 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_007107</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 14"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAN4"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000025">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="49"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="16">
        <location>
            <begin position="418"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW58962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="59002" checksum="52120839E0F62F55" modified="2022-08-03" version="1">MLRRLATSTSAAALRSSAARQTPLAKQALRSYTVHHEAYKNPRSEKFSMTKIVGTIGPVSESLEMVQKLTDEGLRIMRINFSHAEYDEALARINNLRSCRGVHWKPEKNFNLRAVLLDTKGPEIRTGKMRDSKKVKLEAGKEIVLTTDKAFETDGTAEKIYITYTKLTSTVKPGDTVLLADGLIHLTVLSVDGEHNVRCLINNTEEIGNRKGVNLPGLIVELPALSSKDKDDLEFGVKNDIDFIAASFIRKPSDVIEIREFVDQCVKKYWDADYIGPKIISKIENLEGIQNFDEILEVSDGIMVARGDLGVEVPLQKVLTYQKTMVEKCNAVGKPVIVATQMLESMLNNPRPTRAEVSDVGNAVLDGADAVMLSGEVAQGKYPVESVRTMMTVIKEADHLLEHAQYQFEFDPATSDVESIASSAVKTANEMNAKLLIVLTDSGHTARKVAKYKPTVPVMCFTANKKIGRQLQIHRSLYPVVPEETDRRPTTAEAIVAAKKMGWLVPGDRVVLLSADKLSDDLGKQIVMRVADVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB98</accession>
    <name>A0A8K1CB98_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB98"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471698" description="DJ-1/PfpI domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="11"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="249"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="43408" checksum="813C3BF20F73309D" modified="2022-08-03" version="1">MVLDRALVIGILLFQNVTTIDYMGPASYLEYLEPMVGQKTEFYTISEKSGGPIQPGHLSAVFALVGFEDAPRKWDVWIIPGGLGTAPASKNQKYLDYTRAAAESATDVLTVCTGSRILANAGLLDGKKARWVVDGKYWTSSGVMAGIDLGHAYISEKYGKDVAEKMSKTMEYVPNTDPSDDPFYYVTQGSPVPQTMKSPDPNDGPFRVGILIYENTSTMDYSGLVNFLELIKSMVGKKSELYTIAEKAGGLGVDSVVENEKFMSYIRQTAEKATDVLTVATGSRILGATGLLDGKKATTMKMEFGDIAAEYPDVNWVQQARWVVDGKWWTSSGSASCMDMGRAYISAKYGEEMAKRMSELGEYVAHTDPNDDPFAPGAKPVTSPAPSSSRPSKCKLKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBE3</accession>
    <name>A0A8K1CBE3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBE3"/>
    <dbReference type="OrthoDB" id="128190at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="407" mass="45655" checksum="45C453DA88424A80" modified="2022-08-03" version="1">MSWLELSLDDDPETLRAALELIDATVDTQIDAHEDGLSFCEEGCDAEDVTTSDSAEEKPKTSSSRPMRTERKRKNDIVQLKQKVARLETTLSDLQRPRQNQVSTLSSIDAKDVTGALVWRDVALRQRRHRVNAEMENQNLRTMLHSQTLVGQQLLHLLQYTASHDAQVKKELKREAEPTVEQARHLEELVAQADRVFASECFHTPRSSFQDVCVNEDGAKGVVVDTFAGWIVPLSPDKVVSALWSGMLHTEPSNMCKSIRMDMEQKDDTLIASYTLSATVPDRTYASSTGTAVSRRYETADGATLIVSMMSGEMLGITPGSQDTITAIELHWMRIRPYKTLVESEAGVLTQVQLNRQIRLTFSADHSPARRNIVNAVIELVLLQVEEELMHKQEMVEKLMLLPGRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ1</accession>
    <name>A0A8K1CBQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBQ1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="114"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="175" mass="20433" checksum="C57956DE5B92B3C0" modified="2022-08-03" version="1">MEPLRVASDEDVFAKFPRTMQASVESPVHEPSMQTYYGYQSLLETTSMPYTNPEYIPFPETRFMRYDGYEAPRSLRTAEDLRHRSLEPPTPSVSAGTDTDSEHNNDDDVDVSKLSKSELRKHKNRQSAARSRKRSRERMDMLEHLVRELSAKNRRLEQEVRALSLSQQSQHPFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD52</accession>
    <name>A0A8K1CD52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD52"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051881">
        <property type="entry name" value="Copper_transport_ATOX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365:SF1">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="71" mass="7589" checksum="D8399945884B75BB" modified="2022-08-03" version="1">MPKVTEFKVGMTCEGCSSACTRILTKIPGVQDVKCDIEKQQVLVTGDADDQVMLDALLKWSEASGKSVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDM9</accession>
    <name>A0A8K1CDM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDM9"/>
    <dbReference type="OrthoDB" id="206848at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056304">
        <property type="entry name" value="Lip-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24708">
        <property type="entry name" value="Lip_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Lipase-like C-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="447" mass="49705" checksum="AB26CAB9F9C348DD" modified="2022-08-03" version="1">MPNASPIVLVHGFFTQIEAPDGTKNWGRFHGDLAQKLRLQGHEVYTASVGPFSSNWDRACELYAQIKGGRVDYGENHSAHHGHKRFGREFPGLFPQWGEVVDGQIQKVHLIGHSMGGPTSRMLAQLLAHGTAGATIAESPESHPLFSGGKNWIVSITTIASPNQGTTLMDRFFDVADLMESVVAFWFSIKGVSGAKPGMDPQLDQWNIYPYTKDEGVPAYLHRVMTSRMFAPGFKDIAPWSLSTHGAKEENLWVTTLPNVFYFSFSTECTVYNTAKDGAPLYATTKFDKLCISKSLRTFSKIMASNFTTKTRRLPESWRANDGMVNTESMEHDGYGPALDFKGQSRPGHWMRLPIIKHVDHASIVGGQKAVDPSELFFAHTALLTSLPLNAEGITSVIAPERMVKRLFAAIESLTNREPPLIVVPERESKLLGFMNIFKLKRQRNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE12</accession>
    <name>A0A8K1CE12_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE12"/>
    <dbReference type="OrthoDB" id="93497at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066:SF1">
        <property type="entry name" value="LNS2_PITP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="42631" checksum="B4806649AC22E76E" modified="2022-08-03" version="1">MLAVSRRSLACVWPHRWLSTTADGRREQARKFKLLTPAMQAFIAARGHCVVPFHYPIPSSDAKSSSRVDTDGKEKGSIVDWPEETRGLNLGRTLHAFVTNERHQERYPHVVTSLRAIGVPIGVDWQQYVWEKVVMTAIKTFYALEGHSIVPIAFVIPWNDSQWPRETWGYRLGWKVSDIRHEPEVLDEQALVDLERMEFSFDVSETTWRVQIRPSLETFFQLNGHCHVRADFIVPSELPWPKEAWGFSLGNTVERIRLKGNYAKQIANDGKFMEEIGFVRDVNEHNWRMKVRPSLKMFAQLNGHCLVRADFIVPSELPWPKEAWGFPLGSTVQSIRSRGNYAKQIANDEDFMKEIGFVWRVMEPRKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE90</accession>
    <name>A0A8K1CE90_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL18 C-terminal eukaryotes domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE90"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="7">
        <location>
            <begin position="245"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="301" mass="34483" checksum="5ED913C1017B075D" modified="2022-08-03" version="1">MTFVKVTKNKAYFKRFQVKYRRRREGKTDYRARKRLITQDKNKYNSPKYRLVVRITNKQVICQIAYAEIDGDKILAAAYSSELPRYGWTIGLKNYSAAYATGLLVGRRVLQKLGLDEDYEGNTEVNGEVVKTESNGRTYFVEEVADEKRPFRAYLDVGLRTTTTGHRVFGALKGAADAGLDIPHTEKRFPGYNRDDKSYDAEVHRDRIFAVHIGDHMKELEEDDPDMLASHYAKYTEAGISGDDIEELVEKVHEAIREDPSPAAKKEVSIDKKYKKPAKRSLQQRKARVAQKKAYAASKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEH0</accession>
    <name>A0A8K1CEH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2148418at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="1132"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="1165"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1313"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1319"/>
            <end position="1341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1341" mass="158082" checksum="2D53BB8DC070BB61" modified="2022-08-03" version="1">MASTQAALRWNTECDRSPPLSPHALREASGLEDYATVIHNQLIRQGEPAKAVGYTRRPGIPSKPPQRVKLPLKRQTTIPKLTPAVHSNNGDGKEKKPRKRRRARVPASSNQWTSVATHIHEVDDAQIETDNEDEDDGRIHAGVYVLENRKTGHRFFGTTWDLKNAAAQAFADLEDGSHPHHALVTCFQLYGREASAIHFRVLERVQPPALSTVDASAPNRKRSPQVQTFDVNTMETLLRQRLAYHQRRIVRQSAGRLVHRLLVYPFLAEYFPKWRGTTAYQQENEHMAAAVVVQSLIRRRLAVRLVNRQRRERAMHTLSRFFRFCMLKLVLLKRKRRQERHTSAIIIQRTVRALLERCRRHHHALKIRQWLRARTIQRVYRGHKGRAAASSIRAFIRRNQASRHLQRVVRGFLVRRRVLHQRWREYKMNCAIRIQSQWRGVLARMAVRRFRIEQIADKRRHAAASRIQALFHLVKQRSVTQAVETVALYKQQATRIHLAYKNYVAKKFGWAATTFALEHSSALRIQRVLRRWFFFHRIRALLLLKKHELAAIQIQRMTRGFCARCRVDRYRRALRRDQAARRLQRLWRLYSGRLHMQSVLCFWRMDKSARRIQARYCSFHARRLFLVVRTQARRDNAAVRIQNFVRCVFARREWRRRVLLRREGPCEDCGDAVAIVFCYDAALTLCSQCLDKWTESLGVVHAVDVSLHPRQQECVIHIQRVYRGHRTRLTRRYGQCGFCGQHPNRIHCYTCVKRYCWTCDSVFHEKLGHQKAHERRRVEIYLMQEHAAVRIQAQVRRSQQRDTLARRRVDRQDAAATRIQRIYKSHNQRRVTRAIVAAQHERTRLEAHAATRIQRQVRGFLARNELQSLRERKRSTTLNQRVYRGHRARQEAQQRREQRNAAVCIQRVVRGHMGRRRARLRREQVQREMEQSGAVCIQCHIRGWLTRRRLWMEKAQRAAVRIQCAWRRYEAQTLKARLARERQERWSMEETELDQRVRGAAIELAQRSATLIQNVVRQRQARQELARRRLVRAKMRREHQRALWIRVEAASAGRIQRWVRRGWLAQTYSRRLRVHCVARQYLARQVLRRLRLEKYAIVRIQRAFRYARVKRRLTRLVSLESHVVHQSGHCAWVELLDEASGCVYYYNRETAESTWDRPSEMDAVDAESPEWVEYWDATVDAAYYYNTKTGEATWTTPEGMDNQHEDTWIGASWPPGAPIQDIYKDEWKQKTSAAPEMTASEDVMENQWPQDAYGGYYVDANGYAYAYGYEGNAPASSVDNGGGAEYGYAWPGYDAAPVDTEYDINYKIFMTQLERDQAQEGEDESRENEEGEDVGENNDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEI8</accession>
    <name>A0A8K1CEI8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009464</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEI8"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="46930" checksum="F2EBA3C88C2024A5" modified="2022-08-03" version="1">MQVVVVGGGIIGLATALALLENGFKRVHVLAKSFDDITSHVAGAIWMPFALPAHIDSQQTQKWCEESIEWLAKLYRQHGEAVGIHYVDGDDVSALGTPGVTHPYWAHCVENFRLLTQDEAAAVCPGMTHGSSFRTIIYKPMTLMTWLHEQIRQRGGTFEQRNLESLDDVDCDLLVNCTGVGTKALVGDDSMSPIRGQVLTVQHPSIKRFLMVVHRDGQHTYVLPRPGGELVVGGTVQLNNWSLENSPADIDGIWTRACALVPELASGKILGEHCGLRPGRADGLISDIIALPVRDGDLLDLPSAVSRFLLDVDRNGTQTVVLKKPNTTSSSHTASHLQLPEPSTSLNGIWTRSYALPPTMACRRTLSSHGAMPPKNFYHVQRAVMEATTPHRLLVVLDCPVQSALEQDSVLNRLNRRNMPHIIAQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF89</accession>
    <name>A0A8K1CF89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="3 12">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_009854</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="3 12"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF89"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000050">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000238">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="211"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW62361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="557" mass="62716" checksum="FD9CDF34323A036C" modified="2022-08-03" version="1">MMIARSGHLRAAARALRLPQRWARGLTTAANDENSAAAAFERFEGIPGFEKYPHTFPVSMNLRDFQQKYADLPAKARETEQPVNIAGRIVSIRAASKKLIFLDLQSDGARIQVLSELKHFQGRSGSTDAAVVQDEFQRVHESLRRGDIIGVRGFPGKSGKGELSVIPRQVEVLAPCIQPLPNSKYGIKEPEIRFRQKYLDLLTNPGVRSIFETRAKVIRGVRRYLEDRNFIEVETPVLFTAAGGAAAQPFVTRSRALGKDLYLRIAPELFLKQLVIGGFDRVFEIAKVFRNEGIDATHNPEFTMCEFYQAYADYHSLMDTAEEMVSGIVKEINGSLQVPYPVESAQNDAGDEEQTMVNIDFRPPFRRLPITETLEECLGESLPDVNGPDAIEHLLQLCHRHNIECSPPHTAARLVDKLISHFIEPQCVNPTFLYNHPQCMSPLAKAHREQPGVTERFELFVAGKELCNAYTELNDPFDQRERFASQQADQHRGDNEAHTKDEEFCHALEYGLPPTGGFGIGIDRLVMLLTGQEHIREVIMFPAMKPREGHADEEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFG6</accession>
    <name>A0A8K1CFG6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFG6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035420746" evidence="1">
        <location>
            <begin position="27"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="24377" checksum="16849D682179F0D5" modified="2022-08-03" version="1">MLGPRVLACLFGTALFRASSAPSADALNVAIVSSFGTRSDIAPIFEGLRDFAMVPENKVSFIAAGKGLARGHASNFKEYVETIVVDDLELPEYLETFIPQIMEKKKRIDNTAMFLDGINLIADVYETNVQIYMDYFRQHKFDLVMCGAIEQSCMDAAKETGTKLAIYGPLGQYGVGADWYVPDFLDPMPVGEWIASPWHRAKGYYDMIPFVFAMLQARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFK5</accession>
    <name>A0A8K1CFK5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005177</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFK5"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="10"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="135" mass="15259" checksum="D1447742FBEABBA8" modified="2022-08-03" version="1">MSPTTEMTVHRGGCHCRAVEFEFDAPRELVAINCNCSICLMKRNTHAIVPAARFRLLKGEDALTTYTFNTHRAKHMFCQHCGVQPFYIPRSNPDGYAITIHCIDKGTVDKVTIEPFDGENWENAYAASDITKYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG12</accession>
    <name>A0A8K1CG12_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG12"/>
    <dbReference type="OrthoDB" id="164749at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="680" mass="76662" checksum="0089BAE9BC284378" modified="2022-08-03" version="1">MEDFYQYVGRYEDAGGASQLLDQEKLYVYSSPRECAIDRCGELPVGAYFACSELLYYEDQCWMKTRRGYFSNTKQNGYLRVECDWSDQLAAKQRRCAAFYRPRRFKNLRQLPKFPAFLCARERITLSRIPSFQTSTSSSSAHLDRQLPAASVFQATECRFNDDFTQLALKITSPFGVAGWIHVSYHETLVEVDDPRKPLDGPVYVQNIAPRAGKWMGELPVRGIPTLQAPRLGNLASFQIATAVERKLVKDHVWLRLEGFQSSSSENNQEGGNTEPIVDAWIVEHHANTGERVTVPWGADDIHDRALNRDDYEERYYRNIYGRRALPLRKAARLDSEVVGELSPGAVVISTRRVLNDRGQVWIRVALASSAISNQDEDTDKRDVEYGYAIQSSAKTNVCMLQEIPTPGKMTPKQYFQLVLRSDSSSDAKKASLHAKTDGSPATEVMVDATRLGAFAEPSTKAKTLFYIKNRAIVSAIGSIYNSEQKTMWLQVLREDVDPVLIEEKKLLPHEQREESSGDGARQYVVYVPVCHPEPSRAHEVVMFGVGRELQKTTNPSKVEAERKQAGARVVFSGRASKLFGSQLLRPSTTDIAPPSPLKPLSDSPVASAAGEDQAQHLKEEIDEWQRLSAQQSLVSVKQYFYVAGGMLASCFQRPCRPCLQQRQAQQMYARLDQDEEDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGI9</accession>
    <name>A0A8K1CGI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGI9"/>
    <dbReference type="OrthoDB" id="166080at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.30">
        <property type="entry name" value="RIG-I-like receptor, C-terminal regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038557">
        <property type="entry name" value="RLR_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="544"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="647" mass="73393" checksum="15752EE00BBC8B8C" modified="2022-08-03" version="1">MRAWTKLGARRIATSRARFQRHQLAAVYKDNVRAASFASKYPTNAESAVLDASAEDDKDKSHLVCGKCSSPICKTDDLVFFKWRGGIHVSSLTEAPLQSLRTGSHWNSEEHAWKKHKLNCLTCNHPVGSIARVFSSDKILFSAKEVTIKMPVQQSPMISLSGYPSSMLTFSMWTELLLMLESQPNLKSQLQIRRVDNIRDFSVEKKELNTQLLLASDLRSLLKLVDEHLNEMNAVNLMTALHRAGVLKIAEKKSVTQKPTPRFHVKSEAPEDDLLDFDSHVLLNPAAVNAVNEEINHRLWKLVDAIESVMAFSGSVVESAVRLTNLAAAMWRLNIGRPNILRMIARQAMYRMKAETPLLNAHEASLVASAVASLSSKEIRQEPWVFDLLDAAADVVLADEAAFSATDSIWDVVLPLLRSFAMVGHFHEELSRLAFERVNVGMLEEKFDADQSRGRLTQSQRRIYQIHIDNVQAHRGPEYQLQSGKRLERYQSLFAEEQRHLKNMVFRPRHLVATALESMKLTPVPLYTFEEGYVVDLALPRQRIAIEINDNSVYLARDSASRMDAGDEASADPDVQRIESFKTLSYVDLKARHLEHHGWIVVQLPEEEFRKLNDADHRAEYLSMLIEIATYSRANELDEDFEDKDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGJ1</accession>
    <name>A0A8K1CGJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGJ1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="227" mass="26464" checksum="1A8C76D6B8C6D013" modified="2022-08-03" version="1">MTSLFPFADPLRRLENALRHCAADATAGRRSFLSSIEHLWALWQLYPDYHTRVVLRSEFRCHCRAIMRGLTRAMRRCGVYQLHPIYVCTLVLTTWLTQSSDFRRYADYLPLRDAIARVKGLFGDYTSGSKLCNRIAQCLNLSIGYNHEGLEHKWFNIVHFFQHHEIQRHHMTSYVEMIQQTQDDIVATLGTFFPDSLIFYRVLVPNPETDPREPTKVDKEVSGGGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGJ5</accession>
    <name>A0A8K1CGJ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGJ5"/>
    <dbReference type="OrthoDB" id="167208at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="361" mass="39314" checksum="79824C1AB280EE2B" modified="2022-08-03" version="1">MLMLTGLKRATARTPGLYNAATLRLRTSQLLDRPLSTGRPLASTLFEGIHSENTRLGQPNDRASPLPGRLSAAPVLGVAAGRGSLVNGGVFARHSPVYYHQIRSYSQRRIPDWQRGSWVDTVKTGALLAVGASCALAVASVGFGLIVYGAAGYGVYTLYRKFIAPYRSPSSSNNPFGSIPSDIDRIFRDSRGRRDESSRSTSWMNSSNRSSKEIDSLVEGLPFVVRGLVKTVFSFVGRAMQDSMQRAGELRRLATEYAQANPRVVSQLGDRFNISTPQNWAEYTVNGAGRVEAVFPVEGGAYGRAQITAKANVGSGGDLQLKELKLRNLRTGEVIDLLRDAPSGPRKTVMEAEYVDVDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGN1</accession>
    <name>A0A8K1CGN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytoplasmic dynein 2 light intermediate chain 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009661</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynein light intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGN1"/>
    <dbReference type="OrthoDB" id="10263060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040045">
        <property type="entry name" value="DYNC2LI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13236:SF0">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13236">
        <property type="entry name" value="DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="331"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="397" mass="44267" checksum="7EB15B8415835D36" modified="2022-08-03" version="1">MKPSAVAKGASSGSSTKDIWLALSSMEPLPSAAKENQTQDVEAAKSSGGQEERDTFTLIVGSKNAGKTTLTATFRNSSKTEEIKPTTALEYVFVRLKATSGRAPVAHMWELASSKCIPEMMRVPLAPERILNSALIIVLDLSVPGDVVSYLIKWLVTLYRVVHDVLKAKEKNPVDKLAVDRLRQEAMARYGPSHPDRDEVTPMPVPLWILCNKYDVFRDEDSVKRKGVTQALRSLAHQYGATLLFSSTKDKNLVTQFRSVMKSFAFRALSGLKGAKDVDAARAVFVPAGADLFEDIGFPKTARKHDFSRDQHEEKARQWIKIVSEYYPPSGEVQDADLTGNSSVESEIDAKDAEDGKEAFPELNIDRIRQRKREELRRYREHRKKVLEKAKTSASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHN1</accession>
    <name>A0A8K1CHN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_009800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000240">
        <property type="entry name" value="ABC transporter B family member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="791"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="951"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1036"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="122"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="440"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="796"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1132"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW62307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1398" mass="152394" checksum="A7E08072FDA7EFF9" modified="2022-08-03" version="1">MKGVTEPQTSGHSTPDDVRFSLDALNSASQSQYAGITTPTEGIQPLGATERGITNEDEHRSSLDCSDYELREGETVSATGIDEVNPTNYTTSQVDEPNKVPQSVTFRDLYRYASHCDRAWLAIGCLMSVINGMMNPLMAILFGKAISSFRPLDMTAVEQVALAYFGIAVALFVSDYAAHVCLQLTAERQMHKLRVHFFRHVLYKQAAWYDTNPTDVKHTSQLYATTFKINEGLGAKLGEALRCVAQFVTGYSIGFATHWGVSIVMASVMPLMAMCLSWIIKTLRQRTAFSQQKYAEAGAIAEETLRSMRTVAAFTGESQAVAKYLAKAKGAEAENIKMVRVLSIVLGIFVGTIWITYAAGLWFGARLVADRKTDPGTVFTAFYGILIGTISLARISPNFASVASAKACAASLFKILDEASAVDASKEEDGLIPHTCQGKIQVTGVDFAYPTRPDMPVLKNYSVTISAGETVAFVGPSGGGKSTLLKLLQRFYIPQAGKITLDGHDIATLQLRWLRAQIGVVGQEPVLFATTIFENIAAALDGHAHLKDEERRACVEVAARLSNAHAFISSLPDGYDTMVGEQGVMLSGGQKQRVAIARALVRDPQILILDEATSALDTESEAIIQAALDTILQTRNRTTLIIAHRLSTIRRAHRICVVMDGAIVESGAHEELMSRENGKFQQLVQTAQVETGMVPRNASLEWHSSWQDVLDSDRSSSMPILTTRSMDVTLPDSKRSELVHMLQNSDMDDCTQEKSSLETVKTPSTNATKASTGGIYSTMRRLMYYNRPERCYMVSGMIAAILNGLSFPCSAILLSAIVSTMVNKYAAYQFSMKHMYLHDLYVEVWWYAVAFIGGSIGLIAINYIQSFSFKYMAERLVTRLRDLHFRAICRQEMAFFDDSRHGSGALASELATLSTQAANLAGDSPGRVVQAASTFIAALVISFWLGSWLLSIIMCVILPMLIIANVVRTNHDKGVMQKDKTGSDATARANALASEAVANIQTVAAFGMEQKMIDEYRRLSLLPLPALAKRAHRTGLMLGFSSFVTFAVYALVFWYGGVLVGRGQITFGELIRSLMAILISANGVGQATSHLTNVDTATRAATQIFELEDRPTAIDPFCESGVLPSSPAKGFIEFEDIHFAYPARAQVPVLSGVSLRIEPGQVVALCGPSGGGKSTLMALLERFYDPASGVILLDGMPIHTLNIRWLRSQFGLISQEPVLFAGSIYDNILYGSSAFAGDDRDPDTIERVQFAATLANAHEFIAAFPDGYDTIVGGGRSGECQLSGGQKQRIAIARAILRDPPILLLDEATSALDAESEQLVQDALEVMIKMKKHTTLVIAHRMRTIRNADKICVIANGNIAEMGTHSELMRCSGVYAKLVDSASDERLSMSGRLRVQVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIC4</accession>
    <name>A0A8K1CIC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="1314"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1353"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1393" mass="152999" checksum="DE481DC3AB7DC4EE" modified="2022-08-03" version="1">MRSRKLKNVTKRKETKEGTRLSEKDLDTQTRNAAAQMRVMAELDCLTATPFSVEKSKVLEKKPPPQQKPVKTSVLCYGTNVKSEKLSIEESISEKHAQPSNQSELVEPRAVDSTSTSPRVIIPPDDTTEHMQPMVEVGVSSVEMTDEEQARTLESVDPAITGPLLNLSGETQTDSPSCGVAETHGLEIPNEEPKQLSGDDFLELSGPPASENSPELDSDISSDVREMTKEKDSLGIEDSEEDQSEQQSDFVGDNVTSILVSKEVGSSPGDVPASAEVEEEGENAIEHGLKIIVPEDSTHEACTGVYGSHEDSTSGPESNESTSAGNVEGTGSVRDADILVVQSEEDASSKTDCVPSPSDGIKIPDDKIDGFQSEEPREAVHWCLDHGEDDPMGTNSLPSSTEPRLSLLAEHIQELPTDVRDQISEPFEGDENVLTEPKSAMESAELDPNESQAHPSVADERPSSPLAGQKHESMGTRGEGKDTSPNPATSEPQKEDGQEESIAAKHEAARVIQNQWQTTLVKRMLSEHVDLISRHHEEAIHEQDHVCAEVNEIERSSNELPIVLLNTSPVSSACVSSIGEGKYANDAEGLPGSSRETVLLNNGLHDEQEEGAEAGKVTENSVGLSISTPEAVDDDIDTDENTNMVHLTQGNDKKAEEHVGTTQIEAGKAGTTVTQENDSMDLVETNAKSQVVATIDDSAAKLPVADVHHAESDEKDSGRATEHLAISVFDTQSDHYDSTLTDVACSTVDSPAEDSPMLFSIVEKQTNADDSHHELDISFDGIIEEAVSRVVVELVTGVVDLVIENTNASEEILEKATIVNMMMDTETKKIEALEDCDTELQLVSCDDTPRSIGDENETPLHVVSHAVDLCGGTSPKAKEIESPTSFQKEENREDMASRRIQTQYRRYHARLLMVEEMRYLLQQRRRETRKKTRRESAQVATLLGVAAISETLGIKAGAETPDIQDSVMPVPVTGEANEDKPERIPTEVMKDRPTASEGERGGPREEEFFQLEAKLSEFAVVVEEETNDTPETKEYAEMMELKGDCALPESQYSPHLDTVTDEETNGMPVESGMTNQEDSVGSDPVEVADSSHDDVWERYMDPATNQPYYYHAKSMISQWEAPEDCEIIDRVEDHGAEVVNHYEDEEQGQSTGNEDGVELSVLVTQHSDVMEILLPTPSPSSSSEDGDFFEEQNSQIGTDTKNSSPVASVKPEEPESLAENTVKRRKFALGLLDLAMGSPREDEPVEFTMESHDNEFGKLELQAATEMLQPVEESGTWQEYVDPATQEKFYYNALTGESTWEVPVRVVPQATEKPQAQSPWVQYIDPETSLPYYVNMETYASSWDIPPDLAVTESRNETPWEQFPVEEEGDDDVEVYEIDLYSGRSSRQPFHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIH6</accession>
    <name>A0A8K1CIH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIH6"/>
    <dbReference type="OrthoDB" id="10265007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030865">
        <property type="term" value="P:cortical cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035303">
        <property type="term" value="P:regulation of dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039865">
        <property type="entry name" value="PPP2R3C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12085">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12085:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="46701" checksum="89EF9812B667A779" modified="2022-08-03" version="1">MLERRENYERIPRFFFPTPGRLAEDIASQSRVICKQQVGERLKDLLIEPLELQALTKAVSKYTVFPKLSHFQTRMLSKNVVKSGVVVIDELLEPHALLPISYDGFKQVRVEMYTNYTASSAVKAVLDPRTFLMFPRDEDDCVNGYTLLECIYQLQRSSIATKCLVEHEAVTIEGMVGELELSSIIREMIATATTLHLDLESDFRPFYELICTRMIVLRHDFKANGPPTQIPVDDLLACPAFLEFIQLMHPGLEGHFVKATNRFDPSAVQAIHRQYVQLDRNKNGMISSDELIDYGKKKAFNPIHQTPTHDLTRAFVNQVFAETTTHPPHGEIDFKAYVDFTLLMADKSSETALRYFWNLLDFQKQGFVDAFVLDVFLRDLVQKIREYGDDESITTTRLRVGSTGLMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJM3</accession>
    <name>A0A8K1CJM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJM3"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF252">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22857" checksum="1364552455CBE739" modified="2022-08-03" version="1">MTPPALKFSYFSFSGRGEITRLALVYGGIPFEDDRVDFVTFGELKQTCPLGQLPLLEVDDKTFPQSMAIARYAGRLAGIYPTDPLAALKVDVVLETMMELLVEVVQFVHHNMEAAEKEKKRSELTKARLPQIYSSIEKHVEGEYLLGNVISLGDLHLFDITSNMVQPNFPDFDLASFPKVQGIINAVASTPSIAKYMAERPTPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJN7</accession>
    <name>A0A8K1CJN7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJN7"/>
    <dbReference type="OrthoDB" id="167956at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426605" evidence="2">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="31439" checksum="32636AA5DD4E76CF" modified="2022-08-03" version="1">MKVPSTLLIAPLLVAIAAAQTTTVTPAPTTPCPVIPGWEKQPTPAPSNPNKSTDCIQVSVEGDATYCISGPICSGAGAAPAGSNCPKQGDVAVKDCLKTLKSYGSGDLCVAPVDAQCVKIKTGAWGCVWGSNSSSSAAAPTPAPSTPCPVIPGWEKPTPVQTPCPTIPGWEPTPTPSTTTPTSPTPCPTIPGWEPTPTPSTTTPTSPTPCPTIPGWEPTPTPSASIPTTDSVAPKVIELSASNQAASEADAKTQSHASPVVPIVATVAAVGVIAAVAMIVYKKKQQQKPQQSFDYDEPTIYKSAVTTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJU7</accession>
    <name>A0A8K1CJU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJU7"/>
    <dbReference type="OrthoDB" id="44467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071913">
        <property type="term" value="F:citrate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="88"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="188"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="30602" checksum="F1E847CCC121DE62" modified="2022-08-03" version="1">MTERSQRLSALQNGVVGSVAGMVEVLIQQPTVAMKNAIQQHRPIPWSVPALYRGVGVSLASIAPVSAVQFAVNGKMLGLLHQDPKKPTSDQVKITSAAVAGCFSSLLSSPAELVMTLQQNTGKSLVGTVRDVVQQHGVTRLFRGLEVTMMREAVWCASYLALGPVITQRLHTTSPGVFGSPEEASISQKASASAVGSILAGLVTVYATQPLDTIKTVMQGEALSVRGQNATLAWGTAKRMYHNAGGSLAPFYRGAVPRGARLIGAVFILGKAREYLEELIDERGILQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJV1</accession>
    <name>A0A8K1CJV1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJV1"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="562" mass="60947" checksum="319CA4D9CE7220B2" modified="2022-08-03" version="1">MENSRRPRLGGIQLLDEQQQRELADVSTIGGLQSHSQLESRRRDAQPRTDFTSFARRPTLINEDAMNRDTGILDTGAAATQSVKQTSRLHISVSYIMVGLLFGVLLGVALYEFEASPLVASWVSLPGELFLRVLKCLVVPYVFCAVAVSIGDIVYVGKVSIIGVQTLRVFVMFWLATTAMGIGLALLFRHSFQMKNNLQATSFTVGFQCKGDRIMVLDKSGNVTCSDGQNMTSEAVSAAFQIVDTENVFKKNDDASIKSLSDQLMETFNGFVSQNIVSSLASGHLPSVITFAMALGTIAGRNFFDKTRRVNYLYMTLLQLRNAFFLALEWIIWLSPGAVISLVAGSFASNQTAVSQFLVMYVYVLVMALAGIAHMGVILPLVVFLLSRCNPYNHMKHMIRAYVFAFGCSSSLATAPVTLGCIQKAKICTPSVANFVISLGVCSNSSASGWYYPVAIAFLAESSGAGDQLTPLRFVALFVLAALAAAATPAIPAGGLILTTTFYRAVVGVPTVPSTYPLLVAMDFFVDRIVTVCNVNDDIMALKVIAENTDETVSAEYLGQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJZ3</accession>
    <name>A0A8K1CJZ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJZ3"/>
    <dbReference type="OrthoDB" id="125622at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="136"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="300"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="342" mass="38352" checksum="09D85EA4AE4D42AA" modified="2022-08-03" version="1">MATSICVRCVDGPEVRLEVPRGTWRIQVAEIKRHVLRELMQMDVRHPRATMEDVEETKASDDERSKSIGDDAAVSVHASFLLFKGQILADADDVNLFALTPADFFVLAPESSEDDDDEKEEETEHKSKKRPREEHDTDEHAQQLVEMGFTVEQARNALELTGHDLARAVAVLMGDETVLSASGAVNGSNSARKEWVEQLLRRHPSLRAIESVLPHREMEELRIRAKQNTFQALVLLKESFSMHWLAQLNENPVATLEFLGSSIDPSELPPPRKTTTKKAQPIEVNSPTKVMEVDSPTPISKHQEAIERLTSMGFALDVVEMIYESCGKNEELAANLLLETLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKH3</accession>
    <name>A0A8K1CKH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKH3"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="27"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="340" mass="36605" checksum="1AB3C5B9D5D22BA7" modified="2022-08-03" version="1">MAANTNTTYAAAVPATYRAYVHEHFGELAQELKLRTDVPQETLKNDQVRIHVHAAAINPIDYKLIEWGARMLPFAPTPERPFRIGFDVAGVIAELGSDVTDLQVGDAVLAMGDFVTKGTFAEYVVIDAKYVAPKPAKLSFQHAAGLSLAGQTSYQALVAQGQLQQGHRVLVLGGSSATGSLAIQIAKALGASFVAATTSTRNVEFVQAFGADRVIDYTTEKWVDVLDANSIDLIFDCGVESASWNDDAQRVLKHDTGRFVTIGQEITPIESPVGATYIRFRTQPSGADLLVLTGLVERDELRVPIDSVFGFEDLLGAFKSVKTGRSRGKVILEVVAAAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLA9</accession>
    <name>A0A8K1CLA9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLA9"/>
    <dbReference type="OrthoDB" id="10374892at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="597" mass="66413" checksum="D739A309EC1F3E58" modified="2022-08-03" version="1">MIAALYQAHLVVKTARATYDFINSDVANLPHQLIPEFELFMEAVLRANSPRLPRPPPDAVTDRIVFIFNTALSTLSCSVEKNTAGTGLLLCCATLGVVDKSSPSVKRLVNFAIQRVCGQSEVLHSLDPTSGVVITLSLRCLQRCIIQGASDDVFCVIENHIQSISASLLLSTVFQRETIKLLYRLRHPQEMIYTSLVEAQEFAFLSDQNLRSFVSVLGIVAAENAKFIAAQTSSDSHGYDNEILEDIDAEDKQENYLKDFKYALARRNRIKHANEELISQGLLSAYLPLVDKSLQKSRDIRLQVAAILTLGEFMKLSPKTTNEYFGRVLQFATDTGIPKSVRIACIDVWASLQPLLAPSETKDNGVVAIYTIIGTSIQAKQDTCAVSCHALKKLLFLILHGQVRDDRLVSICVFLPSAGDDRKVIVESFFQQYLRRCTPNKVSRLFFDVYFSLVSAQDDTRDASLSVLTELINLAKDGSIKLEMLQTTLVSEIESKPRRVDSLRLLSQFPVIPAAALSKLTELVQRGVVGDDELEARSILIHLMSGQLQRCKDTLAKKKIQLAIQQLKASDATPRLHVDAEMDTQSIGKFLSEFQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM76</accession>
    <name>A0A8K1CM76_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Alpha-amylase</fullName>
            <ecNumber evidence="4 9">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_009050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4 9"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM76"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03423">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453936" description="Alpha-amylase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="13">
        <location>
            <begin position="32"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="13">
        <location>
            <begin position="135"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="12">
        <location>
            <begin position="393"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="856" mass="93427" checksum="AB01F49AEA378DC9" modified="2022-08-03" version="1">MRQFFAVVHVLFALCALAVNAQILARNDDGTGMHIYFRTAWTTPYIHYNTGAGWTTSPGLKMTASTDRVHFPSEAGWFRFDAIATSLEFVFNSGADVWDNNNNLNYKVTAAGTYVVTSTVTTPPNPLVQVKASDGTGLHIYFRTAWTTPYIHYNSGAWTTSPGVKMVASTDSAFPAGAGWFKHDLPSLTSLEFVFNNGQDVWDNNNNVNYNVLTAGTYALTSTLTTPPYPIPSDPNAPTPTPTTIPPSSGCSNYEGLDTCTSSAQVSYPDSIEARRWQTPARNSSSWRSEFQDYRSLQGYAHVVYASNRLSATVTVRTVLRVTSGTTCTYTYNGASSTSNQYSATSSLMTDLNIVVKCVNGASTWTLNLEPVNFVWQSTGVATPAGFENGQKGAIVDMFGWPYADIESECKDFLGKAGYLGVKINPPQEAVLSDAWPQDGQRNPWYYVYQPVSYRLVSRMGTRAQLRSMIQSCRANGVRVYADAVVNHMTGSGNDINPTHRKGTTSSCSNWGPKSSAGKSPYYTHNFQYQVNAQTGQRPAAEFPAVPFGPSDFHCERTLNSYTDGFSLSNGWLVGLLDLNTGKQSVRERIAQYFVDLLGIGFSGFRIDAIKHMGPTDSAAIMGLLNTYMGGSFPADFIMWGEVILGGEADLLACNAASGFNFYTELDQRYAAAGISATDIAKLKIWSSDYPATFPACGSWILPASRFVIQNDDHDQQQPGSTSRDMGTKGSVLVTSRNVAAHRNFEVQLFTRREADWKIKVVLSSFTIFPDNTPAGFPDGWSDCSGFDTSAGQTCSRSVPYEKAFRAGSCGYTVENFASVGKYTRVHRDLQIVNAMRSWVGMSTVTASQVGITGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNE6</accession>
    <name>A0A8K1CNE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNE6"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="660"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="773"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="805" mass="89469" checksum="4CF02DA142522367" modified="2022-08-03" version="1">MGNRCCKRAETPPADDGEGSNPFKPSNRKCTDLLFVLLFFVFWIGMIIIAGVAYKHGEPKRLVYGTDWKGRTCGVKADAKDGVPAYDFTKYPYLMYPRLSEDIVALYGENPDASDLMSPSALSKFYGVCVTECPMLDKTSPTYVHAYIDYVLNVDPVNKIYTKAGKSVEDEDAGSPWRLMVDTTNVLNRCLELSKVEVQQSARCIDDCSADEIADYQTSGATQTTCGQDPTLNPLRDCGNKECTAFVLSYRASCTSIETSRQEKQVTSARSDPIIDMLSRRYYMVARWIGDVQKAAFPILICGGGFALILGFLWLLMLRFCAGLFVWIVIILVIIMQLVITLFCAYEGNLLNSTKIDAAMTKMGVQSGTFSTYMSDSANYINGSGFKVTEDQVHYWAIACYVLIAADVVLLLVLVFMCSRIRIAIGIIREASKALQTMPSLVFYPVLPTIFAMGLVAYWVVAAAYIMTSASITLKDVQNAAGDVVGKAPPISAEIENNNVVNYLLIYHLFGLLWTNQFIQAIAYTTIAGCFCEYYWTLDKRQVPGFAVMRSMWRTTRYHLGSMAFGSLIIAVVQMLRLGLEYIDQKMRSAKQGNSVIKVIMCCLKCCMWCFEKCVKFLNNNAFILVAMKGASFCPAMKDSFLLLFNNAARVATVSIITRFLMILGKLFIAAFSMFFMFLFIRYPPVSVPTFFLGDLKDIDSPIFPMLVTGLLGYATASFFLDVYGTGIDTILLCFCEDCNVNKASNKYYMSDELFAYIDGPAKKNAFKAYQPTRDVSSRDRPAGAVASPVTAPPIYSASPPKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNX1</accession>
    <name>A0A8K1CNX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNX1"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="45934" checksum="66A6E140E722F5A8" modified="2022-08-03" version="1">MPSTGTATSDHPVFKRLSRDQLVARRRNIGYQTLIFQSSLPRAERCKHCGRRFNSVWKEYLCHVCGLWVCQPCSLVLERERVLQYVTFMRSCVGCLLMLNKWADTIRLTEFAMHPWVVSSSKRQISLTLSDALRTKKESRRAVLLLLNQLGMPVDPNDSFLDGIHEDDWVAATTEGSVGVSQSPEAHENAVKTSVECVQHLVQQCFDVVIPELALKDCVFAESDGIRHYALQYNSPDQPPESPPVPDEDKRLHTLAGYGQVLRSLNTPLLQLICDLVAKELEAWSSFITMVKAKVQFMVAAPPGCPCSTALKRSECFCSFALTSSRPFLIRDTSMDIRFRNIEIARGGQLMFYIAFPIVDEAGVTVAFLCALDHKPRKCVTTMQYSVMKRLAAVVSALWKDIVNQNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPY4</accession>
    <name>A0A8K1CPY4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPY4"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="516"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="677"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="703" mass="78052" checksum="94212F1CB859DA3F" modified="2022-08-03" version="1">MADVSAPHADGTDTNGFTTQTIARSSDVVYDADAQAATPAQSTENLLPTRQVSGRRRSTLKHAPMTKPIRTCFILAMPWAAYSVLNTVFEDVRQPYMSSMGIGDFIPRFVPALVAFFLGPILGAASDRSLSKWGRRNVFLVSAAIILTISGLLFGSAQMLFSTYVGLTNTLFFMLAIGLVLLNIGLRARLMDEVSLEYQVHAQAAVAFWAGFGSVLGSLLFRRTAVVVFVTDISGEDILISFSAALAGIILTTAACIYLRPEHPQDRPPFQPPLARLVREALDQIVYAPRLFRILCLVYFVQYFAWSGFRDEVYNWWARNVYDGCNSAGCDARKQEDYRDGLDTANIALISQNGLQLVVCLILPCAIPRGNKFKRVAITGLCLGAVGLIVAVSVGGAWIPLTFGAFVVVAFYQMVTTIFPYSVVGIMGKEIQESQHGFNNNGLYIGVLTSFSAASQLFVQLYGTEHMSPLGTGNVMFLSCILFVVGPGAYMIPSTFRRAALNEAMRQIHREEYGREFARQQRRSSDPAHCDNEFEESTDQRFEKEDEDPDQTEEQADKYRARRERLRDLLQAFYERPGQDQTFVESPVRSEHPLSPSLSATSNYDAFVEGYRHQSASHSIAGEESLRSPARSSWDPQELLIHTRHLQPATQKPGASAMTPLSYETYLSSTSYSRRLTKLQSRKKPLVRASQCQLKKHSRPSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ09</accession>
    <name>A0A8K1CQ09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynein heavy chain AAA module D4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ09"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF69">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="3">
        <location>
            <begin position="75"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="47672" checksum="9A77056B27AEC4CE" modified="2022-08-03" version="1">MREVSKKNHPDLDQLSLFNDQSAANPEEATVNIFTTFVTQVAGVEAPYLAVASMKHLIKVLVEQPDDYNSKYSMMNLKLFHNAVEHVTRIFRIFGNPGGNTMPIGVGGSGKLSLSRLASHSCGFEVHQLSVTSNFRIDDLGDVPDRWHFGLPLVFLITDSQIVNERFLVYINDMLSLKWIPDLSPKEDIDGLLGALRNEAKANGVPDTMDALVNSLLPRIRINFRIVTSFSPVGAIIRIRARRFPGLVNCAVIDWFHPWPRDALVRVATSFLNKMEDVASKKKKEEAEEQLSWAMGQVAEVPKRLEQIENTLRQATDEKIKVEQMKESSESRPLPADKLLNGPASENECWGIEIEQLKNSGVLVVGNSLLAATFVRLANAPDDIMSDMPLIESLEEPKKNLDLSQAQSRDRSRDQQRARAVSYRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ25</accession>
    <name>A0A8K1CQ25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ25"/>
    <dbReference type="OrthoDB" id="167158at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471300" evidence="3">
        <location>
            <begin position="20"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="23412" checksum="01CC2990AC6E69B2" modified="2022-08-03" version="1">MNPIKFLSISTLFMAAALAADNSTESTCVQVAVLYDATYCVEGPICSGNGTQPAGWNCPTRGAVATAGCHEYLPSYNNETASCEAPVDSECQPIDGDVWGCVWPENNGSSSSSGSWDDVGFPTRTVVLAPPSNNTIVVPATVLSASETSSNDSGSSGSSGATIGAVAAVAGVACVAAGAVIYRQQKRRSAEADDLATAINTPPNGRSAAPLTPPLHYSAKFFPQSPSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ32</accession>
    <name>A0A8K1CQ32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ32"/>
    <dbReference type="OrthoDB" id="102559at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF38">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="50"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18141" checksum="5CA87413D7CB0B61" modified="2022-08-03" version="1">MTILVEVQDEELIAQFTMTSEAPHAETQDLHPQIPRVEPRELADALRNTETKRPLIIDVREAGTGGFIRGAVNVPKPDFDDEEKVEALIAKIKDEQEIVFHCQHSQQRGPTAAYQFLARLEKQLGDGERKPNVKVLRGGFHQFSQEFGQEESLVDQSPLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQG5</accession>
    <name>A0A8K1CQG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQG5"/>
    <dbReference type="OrthoDB" id="158739at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="671" mass="74974" checksum="5F7C468C939451B7" modified="2022-08-03" version="1">MVKLFCALVGAAGSAFPVDIDVSLSVGDLKEAIKTKKPSKIKCDANELHLFLATKGNAWLPDDDPVVLRLEEGEIHEDIQAVIDGEKMKATKTLQYWLFDKSRMPEPSTDQIHVLVVIPTEEVVPVLPQQVDTVTHEDVIWYGTRGSIVTGEGIDLEDPRTLPRITLTTDIIRRLEETHVLLVKSPPMTGKTSLAALVSRSLVERHMEEKKKMVVINFSALAIPNDSTFEEVFRKRCMIDWSEATLDLPASGCTVYLVLDETQVIYKDGTSSPRRKSTVFWELVKFILSNAAYSIRVLMFAAYGSGVEYSRLASPIQFDERIVLGSDQLNFSQAEVSEYVIKWFKGKACFDGLSSSAMEEFCANLVELTAGHVGLCATAIHTLNEVYVSRNRSASDLPSPAEWIRMLQSGSLYQANDNALFEAMTSTRAVKVLKTLDTDKLDRLERIAYGASPDSDADIVEQCLRKGILAQTGRRFAFSSPVMWRFFVKMRVGNIVRALHVPQTLPEMIARVVRAIDYESISQTLGRSLSSDIPLERAWQMEFYKAAYRCTPSTFVTSVDVGALFRSSGFVDFTIHGGDFFWGIELLREASNLAEHIERFAPGGRYSSLGLTEFCLIDFRRIASIDDVAMERIAADMLRCENLFVVCYDARMAGVVVFNSAMDVVYRVQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSH4</accession>
    <name>A0A8K1CSH4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSH4"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="31550" checksum="94AE9EBCF832DEA4" modified="2022-08-03" version="1">MAPSTTATTTTTTDNKVWLITGCSSGFGREIAIAARNRGDLVIATARKVETLDELKTLGCEALALDVTASDEAVKEVVAKANALYGRIDVLVNNAGYTANGAVEEASAKEIQDLFETNVFGLLRVTHAVLPYMREKKSGTIANIGSVSGHITLPLTGIYSATKFAVAGLTQTLREEVAPFGIDVTVIEPDLFRTSVLSSMRRFEKPIDDYQAMTQAVLSFFMSGDVPMGDATKGAQAIVEALTKTGRAEGRVLPHRLLLGMTVREAVEGVLTRTQQQLNEWSDFAEPSAFAESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSL4</accession>
    <name>A0A8K1CSL4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA repair protein REV1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_007642</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSL4"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000001">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="14">
        <location>
            <begin position="99"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="15">
        <location>
            <begin position="342"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="210"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="712"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="773"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="865"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="746"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="869"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW67970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1006" mass="111606" checksum="8BC3CBDC9818916F" modified="2022-08-03" version="1">MSRHVDGGGEKPGIKAFGNGLVRQEDAGKKRKELGEHHGGSFGVYMSHKIQKLRNQNQGFVDGSHRTESILTQAEPTSSSSHPSTVSNSNSEEVTSSSASSTLFTGVHVLVDGYTVPSKEEIRTLVLMYGGGFEHYDTSQVTHIVATHIAVSRLKQLKKMRRPPPVVHPDWILKSIEQNTLLPVQPFLYHGFGDPTQNSVISSLSLSASAKSQSVSPGKPRSEEITTFDRPITSKPGEQDENSFSESDGGSEGEDHDAMLTHMLSQPAQSSPEKRNPGLDPPPLTNSSRDGPAFVRHFFAKSRLHHIGSWRSTFQQRAGEFLSKYKGKPFLRESPASSDRVILHVDMDCFFVAVAIRDKPEYQNVPIAIAHSGNAGSSEISSCNYLARERGVKASMFMQSAKDLCPELVVLPYKFDEIEEVSFQIYDIFFSRTPYVQAMSCDEAYLEFAKGTDGVSMAKEIRQAIFEKTRCTASVGISYNILLAKLATREGKPNGLFHIASPEQAEPFLLSLKIRDLPGVGRRMGATMDELGLQDILQLRSLSKFELQKHFGKTTSEMLHNYARGIDIRPLSIESNMMRKSVSAVVNFGIRFQSWKDATEFMMALAEEMSSRLKNLKVRTKCLTLQIMKRREGAPVVPSKFMGHGICDNFSKSRVLPEATDSELVIGNVCIELLRQFNFPNEDLRGVGIQSTKLVSTIKPTETRTGQLFRTWLSEKDGKTSSEATNGRANKDMAVPRNERSESESHIPTLSQINPSVLEELPPAIRDEIMASYASSSTRGQQPRPQAQPQPPRELSGWQPPRAKGKQKLVVNRAAHNSAQRPRNHAVSAGPVSALNDISFSQVDQDVYHALPMTIRKEINSYAKRRKGTSTSKVPYNAPETQSTAQQATASYDSNQLQTIEELFDCLVASLEYQGLPEEVDTASRMAATSSAFDAIYLRILVEIENHALDEALRMTRYLRRKCQNLIGQRSSEALRIGFNIVLEQVNSGLQMNYQGVFSSRLVAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSP9</accession>
    <name>A0A8K1CSP9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007724</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSP9"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="72"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="538" mass="58639" checksum="B15A62D734C13B38" modified="2022-08-03" version="1">MTQATPEPDPTRSPSAEQATLYQVVVQTPEPINNGEGRDSQRPRYPIRVDPLQEDRAVEIKLLNCARPHMRAFHFAWVSFFIAFFGWFSIPPLMPTIKKQLKLNADQVANANIASVASTIAGRIIIGPLCDQYGPRVIQAVLLIVGAVPVACAGLASNYTGFVVVRFFIGLVGCSFVATSYWTSIIFSKEVVGSANALAAGWGNLGAGVTYLVTPFLFDLVTWDNHVSDDLGWRLTLLFPAVFMVIIGACLYKFSDDSPRGNFSDLRKMAKRGSTESELTLKPSSVNLRVALLQVSRLPVTWILAFQYACSFGVELQVHNVLSLFYYEDFTRSGCDANADAMKCRILTQTTAGLISSLFGLMCLFARALGGYLSDVASRWYGMKGRIVVQSVAFAGQAVTLYVYSQVRSISGSIPCLILFGVFVQACTGTTFAIVPYVSTRYTGATSGIVGAGGNVGALCWGFLFKGVGSRSKSFEYLSAFVGASALMCFCTTVNGEGSMWARVSRAQRNSDYGATRRLMRPETQPRTPDVRVQRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSV5</accession>
    <name>A0A8K1CSV5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSV5"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="213" mass="22090" checksum="9A87A1702C3BB0B1" modified="2022-08-03" version="1">MASGSSSDSWNSDDRWQDFSSSSASGGFESSATRGLDFPVIPTIPSGSIDIGAIAPVFGVANFDDDAADYLEYDKAGRPFAEQINASCGAAYFTGILGGGVVGAAQGFARSPSTKFKIRMNSLLNGAGMRGSKAGNALGCLALIYKSFEYVADAAEIERFVQFDQVTPILASAATGVFYKSTAGPKAMVLAGALGAGLMTIVQFGVKPFYPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTE6</accession>
    <name>A0A8K1CTE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Globin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006066</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the globin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTE6"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase NAD(P)H activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071500">
        <property type="term" value="P:cellular response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046210">
        <property type="term" value="P:nitric oxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Globin" evidence="5">
        <location>
            <begin position="55"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="178" mass="20399" checksum="38AAA8B436255CDD" modified="2022-08-03" version="1">MGCMPSVIHQEGSAMKFTPQFCRIIKRYLPHFEFDDPSTTTDRLVAFAHWSKAYKDTPKTIDLAVNSAVGKLYEKFYEYLFDNSPQLKPLFQSSHHVQGRVLVHISAGMQTLLKSDDLVTKVMELAILHMKIGVKPEDFDSLGVALVHAMKATSGTEWNDRVEHAWRRIFCHIHLDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTE8</accession>
    <name>A0A8K1CTE8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTE8"/>
    <dbReference type="OrthoDB" id="94946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423940" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="6">
        <location>
            <begin position="34"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="17466" checksum="F29D835C8024936D" modified="2022-08-03" version="1">MGLARQCGNAHMGFSMLTLLFLFLAIFLNQLKSDEKTVFVVMYSFAQFFFNFGPNSTTFVIPAEVFPTSVRSTGHGILAASGKVGAIIAELGFSVVAKVSLGLKGVLYIFSACCFLGLLFSFWVPETKGLTLEELSSEGASLNHDDFEHYKEAKTPTVTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTJ3</accession>
    <name>A0A8K1CTJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease P/MRP protein subunit POP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTJ3"/>
    <dbReference type="OrthoDB" id="61519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030681">
        <property type="term" value="C:multimeric ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016819">
        <property type="entry name" value="RNase_P/MRP_POP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023803">
        <property type="entry name" value="Ribonuclease_P_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR023803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="121" mass="13272" checksum="28B5A9A8C27586C5" modified="2022-08-03" version="1">MATPHHKFSLRSEYSYLKIGIFSVDGSAVVSDIKRLKFALNNELRAVFGEVGASMAEFDLLTLQKATKEASATAILRIRSSELKTLWGALTMCTSIDSKLCKLHVLHVSSSLLALASPRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUK4</accession>
    <name>A0A8K1CUK4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUK4"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050969">
        <property type="entry name" value="Dev_Signal_Modulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949:SF56">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7, 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437683" description="EGF-like domain-containing protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="581" mass="62076" checksum="A22074E9E6FD589A" modified="2022-08-03" version="1">MLLVLCMVFASLVHAECPNGCSGNGDCMAKDMCNCYKNFEGNDCADRTCQFGRAFVDTPRGDLNMDQSRETPNWLLTNSQQSPEGTYEYFKPDAQGNEAHFYLECSNKGICDRSTGLCQCFDGYEGSACQRTVCPAKCSGHGTCESIRELGLKAGGTLFGLEGATGAVTYDLWDSNSTYGCRCDPWYYSPDCNKRFCKVGVDPLFLSVGTARYETFVIHAYVDTTGPMPTNSWVRLRLFDYYGESFITGQIPIVTDGPTNAAAITSALKAVPNLTFRNVFCEDVGAGPNLGGYKSARTANAMGMSVVCQYSDNPGRMRIPEVVGYYLGAVTTDVKYVFVGTTAQQGEDDEWFTVQSGMVLDATTPVDATGLVLTLSGTSPSALLSVPAATPQLIKIAQHVVLAESATATTITLAFPLKHTLVTSPSIFTTQAATGASAFGLDAYTDAPASAFAIGSDIMDLGINDPSTATVALAIGDTLFYHNAFFTIQNIYLSGSNYYAKLNKPFGGNADTGDAGAAVDTANPGTIPSPFRVRFPTDKTKLYNYVSECSGRGLCSSETGICTCFKGYSGDNCNTQNIIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUQ8</accession>
    <name>A0A8K1CUQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Galectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUQ8"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001079">
        <property type="entry name" value="Galectin_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00337">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00908">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51304">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Galectin" evidence="5">
        <location>
            <begin position="290"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="499"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="571" mass="59726" checksum="CC4BC22B1E1C886F" modified="2022-08-03" version="1">MTGAMTMETTTTTTSVGAKDASVKEENDTSSLQALQQHLQLEAFDGKYLTSQEILLLELFQGGPLDGGKSVSGVNGAASGAEGLHALNVAAIAASSGGMLSPAGAATTPGSTKANGGPTLTKVSSLPISGGTTPKRTDRERVQNFLMQRQNSFGVSGSGGTPTPRGTSGSSATAAMSNMSALERAKLVMAKKAGKPIGARSTSTGASSGSSTAVKRVNPLADILKGGTGSVVGGVTSSSSSNVAKRPRTGKPDLKPGEIRINGGRSSIQLPVESFLRNEDWDSGTGSALEITLPEAAFASNNTLIIHATMPARSMRFCFNISTQTSMMSGAPYPGTVLYHFNPRRQRGGMIIQNSNIDGRWGCSQPLARCPITFGEPFTLRLTIVPSGFLVFLEEVFQDEFKHRVPIREGENLVLTAPTRDENGNPEGVIVHNVWWGHAEPPANIDTLRRGFPNSGPGGYQRGGQRGYDGGGGYRGGGGGGGGGGGPGPGRFHPNPHPFEVYVGNLPPGTSREELSFLFQYLGYETVRITARGFGFVTLRSAEDMSRAVEDLDGREFNGMKLKVSVAMAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F983</accession>
    <name>A0A8K1F983_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine amidinotransferase, mitochondrial</fullName>
            <ecNumber evidence="3">2.1.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">L-arginine:glycine amidinotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transamidinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014731</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine biosynthesis; creatine biosynthesis; creatine from L-arginine and glycine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidinotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.4.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F983"/>
    <dbReference type="OrthoDB" id="10264242at2759"/>
    <dbReference type="UniPathway" id="UPA00104">
        <property type="reaction ID" value="UER00579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015068">
        <property type="term" value="F:glycine amidinotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006601">
        <property type="term" value="P:creatine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd21136">
        <property type="entry name" value="amidinotransferase_AGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033195">
        <property type="entry name" value="AmidinoTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10488">
        <property type="entry name" value="GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10488:SF1">
        <property type="entry name" value="GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Amidino-cysteine intermediate" evidence="8">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR633195-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW54960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="397" mass="45891" checksum="B721C484E3D27740" modified="2022-08-03" version="1">MHALRIARSQRLQTPLRRALATTKTPVVNSHNEWDPLEEVIVGRVEGATIPEWHVAGKAVWPNKWWDMYKTQSGQPFPKELMEGAQKELDYLAQVLEGEGVTVRRPEASTDYFNGSVKTPDFESKSQLYAAMPRDILIVFGNEILEAPMAWRSRYFEFRPYRKLIKEYFQRGAKWTAAPKPQMSDELYNEDWKAEQGTFNSVVTEFEPTFDAAEFTRMGRDIFTQQSQVTNRFGIDWLQRHLGDDYRVHVLDFQDRNAMHIDGTFVPLMPGKLLANPFRPCITGKPVKTYSYKGKDYEYRLPEMFKGWEVFVAPEPELSASHPLFFTSPWTATCNVLVVRPGTVIVEANEKRAQQAFKDWGFEVIPVPFRHFMPFGGSFHCATCDVRRTGTLQSYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB86</accession>
    <name>A0A8K1FB86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar pre-ribosomal-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72892at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021714">
        <property type="entry name" value="URB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
        <property type="entry name" value="NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11707">
        <property type="entry name" value="Npa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="URB1 N-terminal" evidence="1">
        <location>
            <begin position="70"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 C-terminal" evidence="2">
        <location>
            <begin position="1598"/>
            <end position="1790"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1988" mass="219339" checksum="D97065BBB2C59248" modified="2022-08-03" version="1">MATMALREFLLAAERGKQAVDDAVQQFALALTQQSALAAAFLDVQPQCEPVFHIWPDESGKGTRWEDRESIAVFLQVVLKLLQTQLHERGNVDAAEAVALKIVREKSANLVKLMSWSDKPIIEFRVLELLTQMVRVSAVVAREFVRLFDFQSHAFAKMAARRMKVLTTTEKPAVDEDEDEDMEAQQEKPAFQLREAYVRLVFALASCPDKSVHRFALKEGGLVSSVFKSLDGDDAEMLSLVLSQLDKLVLQNANLDRRSKAALFNTSAIQQLITTLRSEDGNVAELSWQMLQKLFFADDALYRVPPHQSLRQFLVKTTPSVEGTDESPVENASWSAKEIRSALTAIGLNDYMRSEYARQLVTAFITEYPGLLVEYLSVVSPQLEPKSDYRWFAVASFVQKLLSSPLDAAVSDLQLNRGVDSPYTAQLLATRVILPLSCRKELSRGLQHTNNLVIFSSLNIVESVLNRYQALQSQIPTTVSKSELQNELRFLVPSPEALVSLLMKLCASVDQVGLIYIRALTVLRLYLECLPQAMSEVKADFTKLLAWDYLEVSHSGAGALRGVILGEILRLLMVVEDNRLMFLLTSGGGNAQNRSKLLQLLLLYASTSSEGVQYLARSVLHRIFNNLKVFGINNGSEHATPDEEIGVWLDNLKTGGPDSALFVELVLQELVQDPFSFVSVARSYMTGRADLSGSGVISPATTALVAAFNNLGPERWSTAGSKMESSCRNSAVVSFGARVLTTILCRSEIPEVLASMICGQQDDGEREQPSKKRRRTDSLDLSAASAFQVLQVLCKRVLGSSTSSSSSSRNTKPSQWKGFGEEDIGSALSALSPSTFVAHFPAIAAEVLGRGYSPNYIYHYIESRPDLDLLQVLESAATSKKIAKSSFVEALPLHLFSRCIVFQLALNGNHATRDESVKGLLAKLTKRLSADLVSPTEASNVVEELLLCASVASTSPTSDDVASKLAQVLLRLLIAHGAGANSSVPVINQRILQKLASTVSVDRAARAGFRQKLLAVDISSRIVINTPARDLKQRLAASPTVLAATLSGTFPPALRLYALSKLMSLGFALGSSSQHRPLIFQLLRTLDGLAVDRSVSFAGKLSTKLWRMMLQSELKDEMSMIAIYSSGLHLIAQLGGVRMSLYQPAMSAAWVEKVVMCLKNASSAEYSEVVTFLRRLKTVVHTDDAVLLDEDAPLATLIDSVLSRLKKENGVTVLLAVASSLEAIGSVSPALSTTAHDVVVRHAQDMFHRDDTAVDALVLTTVRALAKFNDESPWAADALKHIATSKKISHDLIPSRILCLVILMRQADVEGLNSSGIVEFLTQLVVKRSDSSTIDDRLRARAIQCMIKHIVDAAEELTPTLQPKISTVLKALSSANVSTEAEYVWYVEALASILPLCTSNEFDLQPHFKTVIESSFFVSSLANPVINVKLLRVVASLLTFTESYDHRELFQHLLAAYRMSITLSDRIIRVLLSKFEARGSILASQYGYKFGTSFTTTSMKTDDGQFRNDLVEDSTWLLSGGLEQNRIRATIEQFPLEREISVEVDEELLQFDAALDDESAKQGDLAVVYDPSFLYPLLSYYIARSAITDAVAVQHGLLGLAIRATSSNADDVREYAYAILAHLYESLSGEVSDFKSGRQIHLLLDTLRNALEESLEGVSSVITVFMNDAISILNRPNHSMYPHLNHFLLARPALDLSDVPMFYSLFNSRSAQTYKQERAWLLHNLRRGVREDADVALLIRRHVPSILLSFFGSDLADEHTQMLVGKILLSMLKTETGSTYLLTKCAFLEWLSLHFEHIALSSSSVHKMLVELFDMAMKASLWQQVEYEQRRALSSAAVNCYAAFAAANLRRGILHAEAVREFTTRIAHQVLHEAYVACSLPTLTAIYSAVDGISNVALECADELIADHLLQHPDFQKDRFNEWSSLLSPVVKLLSAVIEGDSPLSLQEQVTGKRIVERLHELLRQAPTLKKLVLAEVRDDLAASALLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBY1</accession>
    <name>A0A8K1FBY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-disulfide reductase</fullName>
            <ecNumber evidence="1">1.8.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006591</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-dithiol + NAD(+) = [protein]-disulfide + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[protein]-dithiol + NADP(+) = [protein]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBY1"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052259">
        <property type="entry name" value="Nucleoredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13871">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13871:SF96">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="7">
        <location>
            <begin position="29"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="163" mass="19130" checksum="70B3E61E7C7D6B49" modified="2022-08-03" version="1">MTFLHKLLGSALISRRGEVPTEQALENKTTIGLYFTASTCRPCQIFTPVLATVYRNMQLNAYRDLAMKDEMEVVLISMDKSPLAFQDTLLQTPFWALPFRRREEAKELWKRYDVKKIPTLIFVNEHGEELERNGRTLVEAHYTDLRKIWSEIQRRHEEAEAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC05</accession>
    <name>A0A8K1FC05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC05"/>
    <dbReference type="OrthoDB" id="4866634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF33">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="511" mass="57202" checksum="CC96C6D3C1433B0D" modified="2022-08-03" version="1">MLDLLLSYTKGYNVPRDASASTSASALLARCIVLPIWKRLLLTAVEMQCHALIDSGALLAGVPTHTAAIFLSSYLPESVVGVTYYDTRKMFDCWVVLDKARQLVTPLKNSPVHERDTFVIFDEARSRGSDMKLLSDACALLTLGPKMTKDKLMQGAGRLRQLGCDQKLWLTSTGEVERSIRQATGCESASISVAEVLHWVVESTQQLCTLGLLEWAQSAVDFCGKESDSKLELKKDDWSLEGQYAAAQVPMKISDIVHERIAAYRMRHSSRILVQVENRATTYARDDTVLVTTYGEECERELQVEREKELELRKPNDVRKPREETDWGYTVLLGATSIAPLTRTFDLARTFFALQDVIRSFLAGSLFHRIAWRDTQIDGTSNFWQTVLAPTFFGSVNNDFGRYLRMIDVFIVFPDLSVLLLTKREADAVAKLLSSTPASPGGRFRIVHLEFLFSAVQRHGPDVTLSDVPLSIGYPDDRALANIVLPPLVLMACRLFNGDTDFLSRTHPRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDC2</accession>
    <name>A0A8K1FDC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDC2"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="317"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="619" mass="69490" checksum="D25D6C3567B381AA" modified="2022-08-03" version="1">MMFSDTPTTDATAQSKASTSTELGVDGLGTKDTHVAHVRCVDGDDHLRLQLRICNDRKTFFRPVGEKLDKIRNRLQLLASHALASVETGSYDVNATYKDRKREHKRNAAENKKLNMQGNSGAAKIAVRFFADEDEFTAKSTTIGEALMRTTRIVIGNDEYVVLRNQPVVLKIAVMDPVLAGIPIIPLPETEFCHPDECQWRWHRIDADGSESVLSDTRRYVPTSADLGCRFRIECHAPSMHSKFAQESAAEIVTTAVIPGPDRSVFAKRKLAGSSRCSIAEGAFRVMDYNVLYDGYTTTLQAKTALFPYAKPEVMTEMYRMQLVFQEIEENQADIICIQEMGQAIFYSFFEPMMGSMGFHAYYAGKTGTTQEGCAVFIRKSCFDVLDDRIVDLSMAVQYSQDAEMNALLAELPEIAKGIRRIPSIAQVLVLRDRHDPTRRLVLVNTHLFYREDGHMIRLVQTLATVREIERVRASLVSEEAGHVGVLFCGDFNAYPHTAPIDFLLAGSIDEQHPHWQSAPSFVWKRLEGKAQQNESTQVSRGRLAHSLDLESTCGLPAFTNYAATFQATLDYILVSKQELCVRQMFPLFTVEEVCEEVAMPSSKFPSDHLSLIVDVQWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEG0</accession>
    <name>A0A8K1FEG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEG0"/>
    <dbReference type="OrthoDB" id="168051at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="39405" checksum="8F5331FD05CE083A" modified="2022-08-03" version="1">MMLWSEELNALLNQCVFEAGYDFTVAAALLLRRGKQLRLLRDEDVELGLSSDECQVQWMTINPIEDDQDQEEEPEFHFYQQHRSPSPLSPEEEPLDDLGGSNEVRGASLLVDPVDPEPLAVTDRLDVPDGCPRLELSLSDAELDVLLNSLPVDGRADAKATYPTSSGSNEMQWVLSFLTDPDAIAHRDADAKNLLLEPQDKREDDNYQFFLQQLNQANLLGPAKPITIETPREAIDVDSNDESDPENAEGDNSTDHDDEGDEDDDDWEQARQQIKQQLPVERDTSSSRAETQPPAPPTRFPPRSMSTSTASRTVDGKGSASTRLALSREIGASLQKHGAFQFPKRLFPAPELQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFE6</accession>
    <name>A0A8K1FFE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFE6"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="688" mass="73891" checksum="2E04A853D71563D2" modified="2022-08-03" version="1">METLSAKVTGHQVTAAATTYTTEVAVDGVAPWTVNIRYSTFRNFYGALTKADKTFSFNFPKRGLFGSSQKPENRQPQLHAFVEKVVAHFHARGHPTELAKLVDDLFLVTRNLIEAKEEKKVEEPVEKEPEAENQASDEESAVTEEQVTKAPEPVIVEEKKPVEEVQVVEAAAEVKETAPVEEAAVVAEPVVEPPVQEPVAVVEAAPVAAVEEPAVEEPAIKVEEPVAVEAAAPSAESEVASAPESEVKVEEPAAVETVETVVPEVVAPAAEVEVSAPVEEPAVVEAAVEEPAPVVEAPAAVEEVAAVVEEPKVEEPKVEEAKVEEPKVEEVKVEEPKVEEAKVEEPKVEEVKVEEAKVEEPKVEEVAPVAEEVKAEEPKVEEAKVEEVKVEEPKVEEAAPVVEEPKAEAEEVVEVEEVTITEEIKVGDDAAVVEEVAPVVEVEEVIVVEEPKAEDAKVDDVVEEITVTEEVTVVEDVKVEEAAPIVEEVTVEEIVVEEPASVVEAPKVEETKVEEVAPVAEEVKVEEPKVEEVKVEEVAPVVEEAKVEEPKAEDPVVAEQPAAVEPVVEAPVVVEEVAAAPVSEPVVVEEAAVAAPVVVEEVAAVAETAVTEPAAEVAAPVSEPTSACTSEEGADEEERSSEASGESPKKTLSPEQKRQRNQRRKSKRKNSRKRISLTSADDSEQAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFH2</accession>
    <name>A0A8K1FFH2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tryptophan synthase</fullName>
            <ecNumber evidence="3">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006813</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFH2"/>
    <dbReference type="OrthoDB" id="10050244at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406:SF1">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE ALPHA CHAIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE, ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="214" mass="23076" checksum="3AC65EF0887ACE57" modified="2022-08-03" version="1">MNRKTLMQTGANIIERAHRIGISQGISLRDVLSIVWEARKMGLSVPVVLMVYSSVLNIGSDKLCVEAKKAGVVGFIIVGVSSEDAKTLTNASKKHDLAFIPLIFPTTPEGQMREIGALAHGFVYCVSHNGVTGIRPELPANLSSFMAKVRRHISLPLALGFGMATRRHFLQAGVVADGVVMSSKIIKTIDESPNDTASRTANVEKFCQSVVFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFM1</accession>
    <name>A0A8K1FFM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFM1"/>
    <dbReference type="OrthoDB" id="44355at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46674" checksum="01EFFADB5CCA31A9" modified="2022-08-03" version="1">MMMMTPQDPMAMATATGSESPTSPGLSVNERHTQEESISSDQSVETDKFVHSMPYVKSRDAVETLFGLERRSQSARRISTASSVETATTSSSPENDEPLPRMMPTSLSYSVPTMSTVTNTPRGRPHVDVIATYMNTSDSRSVKADLLRSHAHFSSPHNSLSRIRSSSMMSKEGSADWGWFADIDSSSESWGGDGSLTHLRRKMSADLGLVDYGNSVHVLGDEQTNTRITAAHKTFNIVTDGKSKVVSATISIPKFRIVQSRAGSDRHAQYLITLKLGKELYADWRRYSEFGELSKKLDLDRYKRSHEAWRNIDTRWFNRLEPSYLHQKCITLENFMRELMYESNEPSVLIDFLGGYLAKVNSRPSDPAAYRPAAQLPKELRPPQPKHERELFEKMWEENFKRSRVDYSAVPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFQ7</accession>
    <name>A0A8K1FFQ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFQ7"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="2">
        <location>
            <begin position="227"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="373" mass="41931" checksum="42109548E1426F70" modified="2022-08-03" version="1">MMTIPPAFALDRRANADAPSSLPSFVFAFLRPLSVSQSHYASPTSHENHSVAMHKSPEYYSSPHEHRKPTWSAMVSSPESPRPRFVRTSRYLREVDRRNILERIQNGEKQSDLAKEYQVSRAAISNLKHRHKRKSHSDEAMPYSGHSTPISYRETSPRGAPYPTRPRWSASLTPRSMAASQHSAEIQLPSMTRLLAQLQDHQLPDAKLRLVIDRMTRLLLEEALGRVSNEKPVSAVALDERGEQFLHEFQLIEVSATTGQLQTRHDSEDGSLRAAFVSKPSQLTTSSVLVLDTHCSSSGRELIAAIQTLLHAGVNERDISLVTLFSHKRGLDCVLDAFPNVQCLSAKVLSPSTERWEFLSELQRRLATRSTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG19</accession>
    <name>A0A8K1FG19_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG19"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="49619" checksum="14604D5D5ACE48C0" modified="2022-08-03" version="1">MSTDWNGLEGIDAEADGFETLAATLAFIDGNFSPLGGEAPLVTGLNDELPSLFDGHDDVLAVLSMEKKDAVGSEKRETMSPVDKTTQKPTRKWKNTPKQELERLRVTETELKAQLEQLKRKKASNGALSTSESGLWQQIASRQSKERENALVENAKLRDMMEDNIRTVRALERILTKRRSQPELLTWAPEKRMRILTASDPLDDVALEVEMRQMALDMYQELDRICSDPRFQTETMEVPLSITDLGIDNLGRPVVEVIESRLLPFGLHETAEAMWSLWTKKSYGPIKMTRLTKLHVTEDTAERNIEGITEKRFINGQFQAKVVSRRFIKANRVVMTGVVLMQPVAINGMPMKGVYTRTRVWNMVCPTIDSQGNQVTCRQVYNLVSTEAFDSSSPLDEQEQCIDQLKQFVLSNETSKADFIHQALENQLVNKLTKLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG52</accession>
    <name>A0A8K1FG52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein FAM227A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM227 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG52"/>
    <dbReference type="OrthoDB" id="192208at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029417">
        <property type="entry name" value="FAM227"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33560">
        <property type="entry name" value="PROTEIN FAM227B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33560:SF2">
        <property type="entry name" value="PROTEIN FAM227B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14922">
        <property type="entry name" value="FWWh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="63207" checksum="640AC80DEFFB5183" modified="2022-08-03" version="1">MRTPGHSAGRHDGEDMDSKHSMNQKEALTAQMIGIISSRLSALQSLANDRKFGLECDLRVSSEYSSKMVPALQDPYESRVSAGNRAKTVSTTILAGNQAMMERLFGPDEKTRLRTVLKKNKAELQKNENRRNIRVNLEKQLQASVEGHITRTVESFTYGGNAADDSVSMGPVITVNPKLLLLHTFERMRVTQGKKNLKRFLLSDTSCALFEDVFWLVFCHFFQKRSDSQQHALVDTISTRYVKMLASLRGSSDYLFRIFPYAIASGVCWGLHYLFPGSRHLYTAELKGEIFLFVCQLLLGLKLCPVSIQAARRQIFPEETLDDALFKSKSLASVSAASAPTESSSSTNMPDLSPLLPRLRNCQSATSFDCGFNQKSLALSSSESHLLKQRESENSVDMILTRDLSLASSASSAMFMNSADETSARLPRTHQVRTLFNASQLSPLMKEYLGAERRNLKKPSFLLRTTPLSDCPVGGEDTYQKHYQRKSQNHAADALREQEKFLKDIQHVQHETRRELAVLNETREIVLNSGKKALQAYCTMLMSKKSHAEAEESGNSSGAPGRRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGE9</accession>
    <name>A0A8K1FGE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polynucleotide adenylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014321</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGE9"/>
    <dbReference type="OrthoDB" id="407432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="188"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="341"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="9">
        <location>
            <begin position="472"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63832" checksum="93248C9DA42D70AB" modified="2022-08-03" version="1">MAGVEWCSYAWFVGCDGDLSATHEVLSRCYNAGDRVTIQDAACVRRIHQALLLIDRVRGLILSFEVGNYEAIVDDAIHLLRGDDSDDRHKQSSSVIEKTALCDLLEATTELLINDKTQPSSTVLDKWVGLLRGQPEGELQFRPPCKLVSRAVVTKALQEIEIVPVGSSVHSSGAASVLALEILQLWDAEIRQVYQQLIIDDEDERQRMTLAKHVENAFRRSSPWEEAQVIPFGSSVSKFGSKHSDVDLCFRTSESTGDKRYPHRSHIHRSHHASVTQNTLDQSKKTLATISVGLQKLNKKRANPVDSHRVLLLQDFQEHFQVILEALEAENESFGTAVDGNECTNQLEIAQSTLAGEGFSVLHVVTGARIPMIRFAHPSSPYECDLCFDNELMVHSTTLLRSYAENDERVRILGVLIKQWAKQRGISDASRGFLKPFGYVLLVIYYLQSRLGLVPNLQHPTQRNHVNCDQNVVEMLLGFFAFYTTEFQFDKYVVSIRFPSRRISKKLRWGDANAKHWRMSLEDPVETDNDLGRAVNQAAQEKIHDELRRGYELLRAGARLGTVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGP4</accession>
    <name>A0A8K1FGP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGP4"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="100"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="558"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1127" mass="126444" checksum="D5C6C99817027840" modified="2022-08-03" version="1">MQVSTPQKLVLPSIGPLFNRSLLVEHQDTQDFHHANLRTPTGVHALASFDAAFATSSPVKKEYKKPGASKDLGTFKLDALIGSTSPTDVTDSSGSLADEEEKLRLSRERNRLHAQRTRIRKRELLESLKDRISSLQSEFAVLKQAYESHVTAMYLLSLGDLEAHLSIRGMEDISDVTDVMQDVAQVICVNDEDVDAAAAASGQTSLILHDRSCAFYHMDPDEEGSGMEDVPCACLERGSEGKRTHLSAATTASLLTCSKEEREQIRRERNRLHARRARLRKKLMLEKSQQAVQSMRSRNEALRARLAVLVTTIYDDDEDIFEEDNSGEDDSIVEEEQFVDNGEGTDEEGERIPVRPHEQAPAKAQRSFRDFQSPRVALQRTTEGEKQDLVTHPQDTLQKRREEHFQACFVRLDPPLLRGLAHLDLSSQKLKLNDLKVLSSNLFLFQSLTSISLADNQLDDTCNKHLRSIMCLDGLKKLDLSCNLLGRGAAKTIADRLKQRLSLESLDIHGNPWFFSFDDALDVAYHLAQGIAVSSLLQVRLSAGKAQPHLMRERCILSSPPSSPSRQARQSKSQRGFEQSDQGANPAEALTRELVELYQGGAIKYPKLLSFGLVHAELSRRCIVNLMKLAPKLQALDLTYAFIGSASVRIIATALRMPSYSSLTQLNLRGNRLRSAGAISILFALRVNSVLTDLDLSGNDILPDVLPEVAQTLMANHAIVRLDLARNHIFSDTSSEIDTTRKFINSIRQHPALLSLGDLSCIDARPDIQDSISVALKENREAQNDLVLLAVKQTLNFEQHLTNPKTGAKTSTTKVTAVTLSSSEHMGAINGKRVWLQSKPIEKQSRVSITWKSKHFIVGKDGMTSPCDRVAWKIRVLRRCEVTGIVEEDAAVGVLSPSSPDDPYTLCSALVYCDESDKLELHMFIADDQDEYNFQSTRQRAFSVKILIKDVVIVLHSITSRHLCFAYDLTDPQETPAQAEWTRKPVRIPSRDPFPYTTSLQRLYISRTHNYRLVWRVKFPFRVSRLSNEQKEDFYSQFYWHIIRSPCWNPELSENIVEGSTNEMQAAIRSDNEAVFVTSVIELVAGEYLELQVFATKSDTPLLLTQLFLLYETSAWDSPSGPRLPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGU9</accession>
    <name>A0A8K1FGU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lebercilin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGU9"/>
    <dbReference type="OrthoDB" id="74754at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028933">
        <property type="entry name" value="Lebercilin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15619">
        <property type="entry name" value="Lebercilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lebercilin" evidence="3">
        <location>
            <begin position="130"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="55929" checksum="72493D99D5146592" modified="2022-08-03" version="1">MEADDGEYELEYEAESPAKNDAQSALEASEEDTEAKEPSQPETIDTNTTAADGNDGVDDEERVERLDEPTAVEGGDLTARKSPPKGRKRRLVVKESDAVAALTRKLKQFQKMNADLHHQLHKFYQNEAVAFLENKSQEKQRQIDSLQQENRALANQQRALTKQVEELQESAEKYPQKRQAMRDELRACREQLRQFKEKHQTTEERSNRAHQQIVDLTVKNKTLTERIRQLESSLTASTRALSAHSVLGGQDAEAIIASQEDEITRLQHRVDVMKKSIRHDRTKHEKELQASQDELEQTRSTLQDFHRQLFEKEKTIRSQYLQIKHLKRSLKDVMSGVGTNQHLQQYMIERGVRHSRPLGPSSSLQSQAGLSARSVSQLPDNMKNFSKVHEVLSRLKLLPLDTDTAESRSIDPVQENASLKMGEPNHSVQPPTFIPCPPTLITGERKASSSHRSSRLVAHTSKAVDPEEQMVPWDSEEPTYPNSRGSTSTRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHF0</accession>
    <name>A0A8K1FHF0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000986</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MLO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHF0"/>
    <dbReference type="OrthoDB" id="68481at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004326">
        <property type="entry name" value="Mlo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31942">
        <property type="entry name" value="MLO-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31942:SF52">
        <property type="entry name" value="MLO-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0568">Pathogenesis-related protein</keyword>
    <keyword evidence="4" id="KW-0611">Plant defense</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="533"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="79807" checksum="6FC644A538E23692" modified="2022-08-03" version="1">MGGDNPNAGSIFRVGDNVELWRVLEHLCFVVLFVIILEQALHRLEHQAKKHAKYHEIMTKVFGELMILGFIGLGIKALKELVHLNAYSKNMIAFQAADIMVFILAVALIIQAISIFINLRSKNIQVAKAELIGSTHLVDMVKVEQKKTKTFASRLCSLVKRIDKTAITPAEYTQITEIRILRHFFLKTYKLPDLFPFSKYLRQAQDNQINHMIEVEISTWIILLLLGWVMMVVADLFEKHLTTMEEHLAVVAAFMTLSWLAVALHLAIYLYFIWAINKLLEAASGDTSGSKGSMFTKLQEIAHVETLAAEQDVATDAVAVMQRVREAEQARKIKRRRGFLAKHDTGFQLMSTVWRQASSRFHRGADKKSQLQPSSYTNLTTVQIDVEQNDSRMKTPGSFDKAERLSATPQTTLTDTGRVHIPFFSRKAWHFVVMSTLMLNGFYFALFCQCVMYQLGRIADHFGLVAAIFIPLPLIVNMLVFQPRVLRNFILVSSIHRVDDTAMGDVIDHFTETIELRAEFVQCVNDHLVQSGQTLEDIRLEFAELDAKKTGMVDVDDVRLVLSNYGFNLSFFRFHTVAKLLFQVHGTQVEYNQVLCLLSLGQKEEVRKQSTDSVTYMDAVDLDTGRSSVVQRRSTSADAQSPPRLGLLRLQSSMALLHTNPPGTLRRDNSKMLRALYLMDFTGTSTRRLSVSVQEEGDTTIVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHJ5</accession>
    <name>A0A8K1FHJ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">4-hydroxyphenylpyruvate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_014540</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="15">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Cofactor biosynthesis; prenylquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHJ5"/>
    <dbReference type="OrthoDB" id="414569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000013">
        <property type="entry name" value="4-hydroxyphenylpyruvate dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000025">
        <property type="entry name" value="4-hydroxyphenylpyruvate dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959:SF1">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="VOC" evidence="16">
        <location>
            <begin position="42"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="16">
        <location>
            <begin position="214"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW61079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="430" mass="47474" checksum="9E272FE6F97532D1" modified="2022-08-03" version="1">MSAASPEKRAQNGTDANKKIKLVGHQNFVRHNPMSDKFEVKKFHHVEFYTSDATNVYKRFSWGLGMKLIGKSDQSTNNQQSASYVVRSGEVTFVITAPYALETEKAADAVTPMPNFDAKLAHEFVQKHGLAVRALGIEVGDAKEAYEISVKNGAIGVSEPKVLTDELSGKKTVISEVKLYGDVVIRWISGDYEGPFIPGYEAVDGPDMSIGITRIDHCVGNVPKLIEAVEYVIGFTGFHEFSEFTAEDVGTVDSGLNSMVLASNNEMVLIPVNEPTFGTKRKSQIQTYLEQNVGSGLQHMALKTDNIFHTLAEMRKRSFIGGFEFMPSPDASYYKRLPERIGNDLTPEQFKKIEELGLLVDKDDQGILLQIFTKPLGDRPTVFIEIIERVGCLSDVAGKMEQAAGCGGFGKGNFSELFKSIEEYEKTLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI99</accession>
    <name>A0A8K1FI99_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI99"/>
    <dbReference type="OrthoDB" id="10516738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="398" mass="44708" checksum="0B85B2C3EBED506C" modified="2022-08-03" version="1">MLLRTARRSAGAASPPTTQPVSVPRLLQAMARWMSLYMLGEVFFGPVADEYAKREDVEVPIEVLQEKEREMRELALAASDPVKARELKRIPPDMIPYLDHMLIFYRTVGVLNDDALGEDAETARKKVSSSQEPAPLSPTDSHAGHTDGSGGESPSPVLDDHGDVSPSHDDMNATAATNACNAAGHEKHDEANLSVADENMITAADRVEASELRTEAVEVMAEAEPPEAMSFVQVAAPDKRVGAKTAGKRPRKRRLTDQQIYTVMSDLVRDCVEAKKYCREQELLYEQEHKALTEKKAKYKALKQKLRACKEKGRERRRLQLLVEGQSEKAEPEDKSVKKERKRFKQYKRELDLRFKLMESENQRYKMEIENKLAELLCQVPLALYDAFSDVSTPSALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIE9</accession>
    <name>A0A8K1FIE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIE9"/>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="284" mass="31177" checksum="306A04E6A0DBFF70" modified="2022-08-03" version="1">MRFRGTLAKDALDVLLDIAQAFTRLSTQSSAKTNCVLTLTPASFAIALKSTGDELQSFATLQNARLFHEVSVQSRADDHIGFLCDIRHFHQALQSGRDASAVMLRLLKRDGASFLCLRTRAVDIDIVQSIPIQVLAMSTVEHYREPNVPAPQIAIEMPPLKNVRTIVDRLKAMHKSITIEASKKGTLALRIETHPLTLQTLFAHLRYREDLIDDDEPSEGDSASSCSVTVDAKVLSKAILADGSTTDTVLCCITENRAFVLHSILVDGFGSFTCYLPVLTPDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIY7</accession>
    <name>A0A8K1FIY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elongator complex protein 3</fullName>
            <ecNumber evidence="16">2.3.1.311</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">tRNA uridine(34) acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_000265</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.311" evidence="16"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000003">
        <property type="entry name" value="Elongator complex protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="20">
        <location>
            <begin position="919"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="19">
        <location>
            <begin position="1243"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="604"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="809"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="755"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="810"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW60223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1383" mass="154292" checksum="C31DB635B8E161CE" modified="2022-08-03" version="1">MDGPLSPFVSPDTLWGRFNPDSGTSAICPPMFMISPSESDFIDSVPKSDVFLSPPGSHDLKAVTSEAWSKKLTSDSPGPVLKEQKSETEDSQTDHPLVLENFDLSEVHGRSDETQNKVEMPLEARTGSLRELKLSAHKAKASNLSPSLKRRSSSLQNVLASFFLSVDPSKLRMAEVYSRRYKDHEDKLFSELSERYGAERVATFRANFENETIRRIGEGAVGSSSLDSSILPNFVGEVEATYDQFSSNDPDTPLSPQAAGTNVFRLQTPTRPFTMSAASFEGAGDANLFSPPPSYHTPRNMSPMPAFFVSPQHERTESQDHEKYVILPPPISPTICPSAPSLQQEELTPQSFLPEPTRASCEPISHPEDSSYPQIDTLRMFPKSSDVSPMPDMDAPAQTMKRVSRNSSQVDVEGCSVTLEALLNEFFRKHQPDKLHIAPLLAKEYSGKERVLIELLRKKYGSLSVKKLECKFAEEDRKPEPTAETPSDNPRWFYSHPTFTSRWTVAFLVIGVWICGLLGHNHFKCGVIDAIDTKPMENELLLLSKQLEEFRLRYLPSYLSQARPQSSFCTKWKENEAAVQVLPTPRQAGEFLKLLVFSRTTSSAGGSQLASTTANRVAAREGDVPGSTTLTGPSVLEQEESQPLKVVPAAKLNDHPDPHSTAFIEVVVEPTVGHRTSSSMQSNSIKTANPVEEEEELVATITSSMPSAIPSSLSLDVNEDVHMPNRGIEVTKDQDYESKITQQMHQEQPAILEETPTHSRDIPVDDRAIEDEVTTQIKEEVEGVEASADKFFVDKEADRDLPEGLILDKSSAQAPESESTTQAAQSNESVAEEDEENPTKETKTMSGHEAAYVHAIAGIVDEVILAYEKQEPVNMTRLKNDVAKKYKLPSMPKLVDIISAVPEDYKEKLLPFLKAKPIRTASGIAVVAVMCKPHRCPHIAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTKNRVDQLKRLGHSVDKVEFIVMGGTFLSLDKDYRDYFIRNLHDALSGHSSSSVEEAVRYSEQSLTKCTAITIETRPDYCLKPHLNDMLAYGCTRIEIGVQSIYEDVARDTNRGHTVAAVCHSFQLAKDCGYKIVAHMMPDLPNMGMERDLEGFKEFFENPAFRTDGLKMYPTLVIRGTGLYELWKTGKYKNYSPDDLVDLMARLLAIVPPWTRVYRIQRDIPMPLVTSGVEHGNLRELALARMKDLGLVCNDVRTREVGIKSIHDQTIPDQVELVRRDYVANGGWETFLSYEDPQQNILIGLLRLRKASKAAFRAEIPPGTSIVRELHVYGSSVPIHSRDPTKFQHQGFGTLLMEEAERIAVEEHGSHKIVVISGVGTRNYYRKLGYELDGPYMSKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJP0</accession>
    <name>A0A8K1FJP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJP0"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000012">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="235" mass="26015" checksum="C2917A8C6E5235F8" modified="2022-08-03" version="1">MADSAYSFSLTTFNPSGKLLQIEYALTAVNRGNPSLGIKCKNGVVIATEKKLPTILVDEASHKKVATLSETAGVVYSGMGPDYRVLVRKARKKAQAYFQKYKEHAPASILVRELAAIMQEFTQSGGVRPFGVSLLFAGFDDDGPQLYQIDPSGTHFGWKATAIGKNAESAKTFLERRYNDDLEIEDAIHTALLTLRESFEGEMDENNIEVAVIKDDRKFRVLTPAEVKDYLEQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJZ9</accession>
    <name>A0A8K1FJZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJZ9"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="61265" checksum="7A99ACD129F459A3" modified="2022-08-03" version="1">METPLLTHDALLLTVEGPQQEQLRGFVEGLRHGAKVVFDEENVERTPLLMAGTHIVTADSSVGLKTLATKLSDEEQEAVWLDAQTSATQIIREETKRIFDLSQFIILIVLLDQLPDTFLMAMIGRIDKEHSTYILAAYGLATGAKRFSEFWMYVQAGVLMHAACLPFLALILLNSAAISRGMDQDPAIAKTASTLLLITLGSTPLTMIYLIQKSALQAQGMTGPVALSSILSWVVSLPAAYLLGFHTSLSYLGISLSGLINSAVQGLVLFVAIMRHPSFRETWPGWKVKEAARLLRKLVRLGVSNMLVVTLQMLGLMVVTVLLGTLPNPATAIAVNSIFMSVVALSWTPMISLCTAGAIRMGNALGAGKARRAELTSRITLAMCVFTSTVAMVVVVSTADRVTRIFTTNAETIRSTVTLFHQGAIVVLVVGCMFGLQAIFSACGEQWLCARLNCVFLIMVAAPLGVYLATKWDLDIAGLWYGNCVGALGIIVCGVVWPRRQSWEEMAHKARLNTHLHVEENPPAVAAWCRIFRRQLISHSFALLPTIIPQAIRRAIVALCKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKN7</accession>
    <name>A0A8K1FKN7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKN7"/>
    <dbReference type="OrthoDB" id="62634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="19627" checksum="A8DD2E9E679F724A" modified="2022-08-03" version="1">MKKPATPSAPAAVVVSPPEPVANDAAQKDEESIDVSVGSVPPDTAELKRRKILFNPSAGEVHRREQGSPWRVGPDGEIRQGNQKAQEEQAEKRRWGLAKQVQEGLIHSYGINYGVAELAALLKEGLALRSQGKTELSPTEVVYVQLLVASEKYDLKQVVLLLDRFPKGRNAGGENAQKGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKU8</accession>
    <name>A0A8K1FKU8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKU8"/>
    <dbReference type="OrthoDB" id="5596422at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="49"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="265" mass="30308" checksum="CCB14635E496F92B" modified="2022-08-03" version="1">MLRRLKNDDTNGGDASRNGSPRESEDASPRSTNGADPMTSLQRYRSQTMKDYGLMIEYKHLRQHVPGGIYVLPSFDHPRTWFGTIFIHTGLYRTGIFKFTINLPETYNGPGTYPQIVFNSPVFHPYVHAETRELDLKPKFPVWDSELHYMVAALAYLKSIFYMKDFPQQSNIANPIALEVFRRDTEKFVSLVEACVEESLETVYNNDQNSTIRFTKPSPAHENLRRELFAQLGNSETQQTLEDLDIDVTPRNSSLYSAPDDQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLK7</accession>
    <name>A0A8K1FLK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLK7"/>
    <dbReference type="OrthoDB" id="246406at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.70:FF:000007">
        <property type="entry name" value="Putative sybindin-like family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="16507" checksum="989B9D00605E98E4" modified="2022-08-03" version="1">MLHSLYIINKSGGLIYQQDLSHAAPKLSSNDHLRLGSTFHSMHAIAVLAAPVNSGGIESLETDTFRLQCYQTPTGIKFFITSALGTPDLDVALRTIYELYVDYVLKNPFYELEMPIRCSLFNAGLRTYVDKFNADSLRRRPQGNDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLQ1</accession>
    <name>A0A8K1FLQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mRNA cap-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005958</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLQ1"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000003">
        <property type="entry name" value="Eukaryotic translation initiation factor 4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="25115" checksum="C986BF72BEF90A05" modified="2022-08-03" version="1">MSAEPAVQSEQTPVEQVEQKEVEEVVEVPREITTKHPLQHRWTLWYDNPKKRNSAETWEENLKNIFTFDTVEDFWCLYNNVLTPTKLSVGSNYHLFKEGIRPMWEDPINAKGGKWIFTNARSRRARLDECWLHVMLSLIGESLHDEDDICGAVVSVRKAQDRIAIWSATAEAEDLQKAVGRGFRNALIDFGKNEVLKYQSHADAAASGSSFQNEVMYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM50</accession>
    <name>A0A8K1FM50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM50"/>
    <dbReference type="OrthoDB" id="125512at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424214" description="Crinkler effector protein N-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="17"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="48123" checksum="F303CEDF2602CFC1" modified="2022-08-03" version="1">MVKLFCAVVGVGSVFSVDIDISETVGDLKKKIKEENPNSIGCDAALLKLYLAREGDTWLNLQDDELEKLKNGEISDRIKNLMRRELLLKETRNLNNDAYFSKTFERAEDDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLEDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNWLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKVEIFVKVFDKQCKDRVFSRLKEGSDQTDDPLVMKTFVHVESPETFCFCLRWKHEDNDARWRSFLSMVPAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM57</accession>
    <name>A0A8K1FM57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM57"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF8">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="815"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="841"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="925"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="956"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="8">
        <location>
            <begin position="69"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1024" mass="116409" checksum="4287A0F2312589EA" modified="2022-08-03" version="1">MKGETDAYEMYATPSAMEAEISRRGTEHNVRMTESRPVPQHGYVDPRAPPQPPMNMSEAVGIGSIKDNIISVHGYMHKQGKRTIKGPIHKSWKRRYFALEKAKIYYFHSHLDCRQYFTTRNADLVVGAVELKDALQLRPSARLDLPHKGFEVHTKRRVWVLCPESDEEYRMWFEGVEHAIIANGAGNIIERKLPNVRKYQMKGIATYRVLYFLFLLTGIMELLGMLFWFVVGLEPCDAARPSVDCDTITSTSLIKLRCTDQPLSGWFSPPSWYLDLAGVDNVVCFHNPPIPQWISYFALLFAEILSFTLGVFYYIGMWKPVRRGAQYFDEFEPKVPDEQWPRVDILLCHYSEPAEECIDTLMACVNIQYPPHLLHIFVLDDGYCKAKWTKGNPVPQIELNKGILETAGDLRQEVAQFMYDRVCDPNEEMEVYQWRKLHSSANLPSPSRPKVVNRADCAAGSFRDDYRYPGLPHVTFIGRVKPDPHYSKAGNINNCLYNEGASGKYLLILDTDMQPHSKFVLATLPFFFEDPDRPDKTKYSCCCTGCNSVAKMCCASCKLAGVPEDRISYCSKECFENAMHVQSDVHRRQANGTMSDTNKTKKDLRCVGCDAKLGKNGVCKKCNRNNDEHDDVTSLHRYSDDVKDNAVAFVQTPQYFRDCVQLQIGDPMGHRNATFYDAIQSGQDGYECASFAGTNAIFRREALDSIGGIQYGSLTEDCYTGQQLCAMGWKALYFRKDFEGEANERIRLAEGLIPDSVAGSLAQRKRWAKGNFQIFLMNKKTKYIDPEWKKPEVSTPTYNKSNGFMRRVFYVNGTLYPLGSISAVLFYYITLYFLFSGYAPIYMSGLRLLIALVPKLIIQGLLSALCNRTVENNDVVRSQETWFAYAFTNCTAVLEALWWKITGREPKWFNTGGASRGSTAELPNVVIYFGNVAGVAWAVVRFFAGYNIEQTSHGASLLFASTIMGLFIIYKLGPSVRMSIQEYFGWSYHSLMDQGNFMGYFSIAFGILFIAFWVYIEMPSSNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM97</accession>
    <name>A0A8K1FM97_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WD repeat-containing protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM97"/>
    <dbReference type="OrthoDB" id="20669at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042411">
        <property type="entry name" value="WDR27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44525">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44525:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="157"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="635"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="902"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="938" mass="104215" checksum="6FA868636E7DF4AC" modified="2022-08-03" version="1">MELLEELSWQWRPDAAITAVDSTQRCTAIALQYPDCAVVRVRPSEWPPVRHQSRKRKEPEVASKDIELHGHFDRVCCLRWHACVDTLDLLLVSASSDRVLVWHLDASLNASKTVMVEKLPAEPSCVAFDHTGTLLAVACERDVEVRIIHSREIFVTLEGHIARVTKCEFHPLRHHLLFTCSEDRTFKIWDLAAKALLFQSAVLSAFPILSLALNPVTGDACLGFGDGSLKIFTVHENFAREHATLNVETFMRRQLRRRQRQDDIQEVLRESPNVISALPPWARSERAQETAQIQAIVTGASSVRKNYSDVSDRRRPIVLPSEENAIEIACPVLGMRYLCVDVLNGGRDHDSTPAFNAHGEQELLDREQFILVAVPSHLLSINAFSYEIAVLKDFQTPFSTFDAVAVAKELSFHTAEGSDFMFCGVVSAFLPCFTMVSTSLRHDRTGDVEEEPTDMPPSSNQIAEDTDRRPKTASSSPFKRISMIATGPPPPESVLNLPPLSVRKPSPKPSKKAIQDKPITFRTRIKSSGYGTAPAFSATGTRRTSIAERRTSATATTIKVKTSVESFLKEYPMQCGLLQHFQPKHALPPKTLHQGAIHHIEYSADAKWLASSGNDKLAIASKLPFSRFQGEGNVLAGHDHAVRAIHWSHNNQMVLTTSSDKTTRLWLTDSDVASLTFHGTTPSPSSGSISSAKKALPHDVVDAMFFYMDKFVLSASGNAVRLHQFEIDELFARAQTKKAKKNDLLHEDNKSRKKKVAQWVFGEVQTLTSLTCVNGSFLSSMVIVAGSDRSLRIVDAAVGKTTRVIQEAHTRAAHSVVLPRASCFTSHPPNFYDLLLSSAPNSTIHLWDIRADNCVMRFGQHVNRVHRLGVAFSPCMRYVATGSEDRMTYLYDIRTGRCVTRLAGHTDAVTSVAFNPLYPQLATASYDGTVRFYSDVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMJ7</accession>
    <name>A0A8K1FMJ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004109</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77153at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="8">
        <location>
            <begin position="1086"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1255"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1735" mass="203254" checksum="AEA245DB72AEA752" modified="2022-08-03" version="1">MTTRSEHEEVDDHPRLPRISGGHSTTLSLAKYLDQPEMVEELLREMADMGDEVENEALEEVAGDLEEQTETTEDDLSIETALRQAKEPPRSVLPILSTVSPRTRDGLARLPPPNTEELRRIQELERLAEQGSSRHALYTELKRVTGNNHRVSSRRGRQRRIAPPVLVPKQDTRTKTMKATSPTSSKPRNASKRQREEQIGMALEDRNALLLSLPVSATLNAVPTFSTPPILPTAVRQQLRADHHRLVNQQHVAEKHERAAKVRVEQTLSEIKQFIPLEVIYAFGKGEFASPAQQRATQVLFRVGARLKNNLVVQAMLQWKQVVTSIKHELIVRAALMLQCWWRQVLAKRVLVSRRRIRRELERRQKELLRLLANREDKAASTITRTIRRYAAIVKVDRLRREDAAARRLQRFWRQQLAHWMAIRNLLRKKKRNAAAVMIQTQWRGCLARKKRRLLQKIKTVGTILQNKEIQRQKHFVERKRHGAAIAIQSAFRLWSQRRIDALRRRRAQFDREKTKIVYVQAFYRGQKARRFTRKHRTEVPRAVLVIQRAWRCYKARIKFNEARLRRQADRQALLESSKASRKGFKARAIPQIGKKAPWGTLLQSRGNKNVEKGPSPREVAAATKMQAIWRGRKLRQRVKHDQAREREQVRRAVRRKLNRAALCIQRHVRGIQGRARVWDTVVHRSAARIQGVWRGFRTRRDLIRMRRALKAIERMQKQWRLRRQQNLQAQRTRAARQIQRAARRMLARKWLYTAVRRQQYLAEEQAMGKALMQFTRKRIKDDLLLQSFVFPTLHLDIKKDDALLETKTQDVDLKSVQRPLYKFDSGRHIWKRRGCDGVWHELYRDITGNSFEIDNSRFARFLKALPNNFINQKSFPTQNIDLIFAKMKEPRARTIVFARFNKAMVVVWQEKFVPSDGKKKSPNKPTAPDQDGLISIDKQQQHELCLRFMHDFVLPSTLQNGKYRKMLERLVNERLEWAVNVLRRFSNRITGKERHIQFLVVYRQHQLEKQRARAATTLQRHYRRYQHRAKLKSLLAGLFIEFIDYKGRSVRFRNIGTQREITRRPMFLQGVRCQKIIPLPFPGEEFSAFCERHESPEAVPKRAPARVYCLECEDAMCSSCFARDHDKRETFQAHQRREIEVCSHCGTETATWECLECGNGKVPFCDVCFPFVHAAMEKDGVKVSHRSSPLVVMCIECDAKVAQWQCDVCDDVYCKRCLTRLHGKGERQSHACHRLSYFSVLRQQAQERRTIEAQNVHDQKRREREARRAEEEKERLRRERCATMIQAMIRSFLARQRGKAYMKLVRQTNAAKAQRLKDERIRSSWGYRIKNVVGLAPALKSDTQQEILARRQKFDNIKSTLFFFKRRDSTTGKDTNPKKAKRWTKRARLLVEKAAKSWCISGVQVKILRGEWKNAVGSILSTQNLFTTGFVVVFIPLANRAVVVNWEHLVAYDEDEILRQPYVPPTRRLSDAAHEFHGKLSQVIETAARRARLMYLQTIEFHDIVQYAWVVEYNKAAQQAEYWNVVLNRRTFDAPKAMMAIERMEPEERDRLDRRVAIAKSKLQQLLNPFHPMGKVKLATRRNAVVPISRSLYNQPDPQIERLRMEAEAMQCARFWQDTILPDTQFGSRHVNRFLNACSTAPHSTKHVWLMMRFFQWLDLHDSDAFANGAKAFFRKADDSQLYIVDEMVEMLEKNELKEANETFARLIKLKEETLQLLVANAAQKVAEQEDVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FML5</accession>
    <name>A0A8K1FML5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FML5"/>
    <dbReference type="OrthoDB" id="509821at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019176">
        <property type="entry name" value="Cytochrome_B561-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09786">
        <property type="entry name" value="CytochromB561_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="59491" checksum="EF7ED790CB12531C" modified="2022-08-03" version="1">MTGYDRQALAALEARAIRDKARLTYNTTLGSVCFFLVVVLGFSLPSPWRVLNGEWSSRFVPSLLALGAHGVLVISVVVAFRCAQVQSAELWEQLEAKYLRVSSAKPTASEPTDAATDRMTALNNVMNLKTLRSLSPVDKTTTASAEPDARPSRSFFDLPPVKTVEEGKAYLRRLQQAAREREQDDSAMGFSSSSMFGGGGGYPGDAYGSIYGSASLMPRVYQASGFDPYLRDGPLLDKEEDPLTTSSNPQVAWAQLEDLGLAMFMHLYVRNIRRLLACHVKDFVEAFVQNALELNECGVMADVLLRRVPVQALLCPPGQAQQLTNVTLYDMLHGLTQHPSFVSKTRRVHLFEEHVTFEKYLNVGDATGAEYSSLERQQYVLERLIMLSKDRNLDRFRWNKGSTWKGKEWTEALPSDAEILMNVFSCILDNLLPADTGRDRPFWKSYFMGKAPRRPFTTSVRNRLFFVQTVQRPPHFKVLAKAAVREIVPCEENTFHAIVVYLHAVKKMKAGHLESINLHRIIDAVFQVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMV3</accession>
    <name>A0A8K1FMV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMV3"/>
    <dbReference type="OrthoDB" id="166946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018564">
        <property type="entry name" value="Repl_chkpnt_MRC1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09444">
        <property type="entry name" value="MRC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication checkpoint mediator MRC1" evidence="3">
        <location>
            <begin position="340"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="648"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="777" mass="85732" checksum="D4671C5D9C76B1BD" modified="2022-08-03" version="1">MSGAELALETQLLLQEVTQAKQFEVAVDAEGPPLSEFELAKQALVDKLRKKKEQNRQQLQQRNLKRYGFAGAAAKMTSPPQVPAQPAAQAAGNRVTPVKQKQMGLPVIAAAPAASRKKKELLSSLRKQAIKQGSQEMAKLFGYNSYEEHIKYLNKIEKMKILQSELQETKQGEEGEGPNAVEGGSDVEEADVDEDVEMVGENDGAHDEEDTSMETQDIASGTQDQGEESVLPAELSAPEAIDVEHDDDAATATVSKEGSQASSRSPVNRRRRNQIQVDDDEEDGNEADSEQDDKEDAEEDKEEAAEVVDDKPKDRAAAFRRLLQEEAKQNRQRKRLRKGADFVESEAEEEEEEDALRIGGLGDFGFGVPQAATKESTEAEAERNALNMRDDDLEGIVDDLSDEEKEQAQDLDEIYRRELEEQDRHQVKEVMRNVKEGFGRNRRAFSGLDAAGARGRFNLNELTAADGSKLEAARLGLLESDEELMDDDDEDKEKEEENEETEEEDEEAEMERLLRERFLNQPKIYITSSESEGEEENEVEKAANDTAGEEIESDEERERQQMKLFSERARINRRMQRMKEVQRQVAVENEEEVVKAPLPNLLLEEDEESQELLKVLNRTDVAPAAAANTASSNSSRLPSTARPGVKRFNSFGMSSARSSSSFSRVAKNCKLFSTGSGSSAPKGFVFTSFSSDKAEQGDENTNSVEDSGSQPSSQPGLAKSQSWGGSGSRGVKRPFGTTGANASSAQGSNKKHKGGKSDFFSVLASYQCVSQDTSAPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP22</accession>
    <name>A0A8K1FP22_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP22"/>
    <dbReference type="OrthoDB" id="64243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="376" mass="42514" checksum="24443C4DC5226327" modified="2022-08-03" version="1">MRWTLYDDPALALTTWQWAGCTQIKNSWGWVRCVHFVFAVDTIFNLCVLLLVIFRNYQRRKIWIGDAFVSISDSPLLRGLVILAIWLMENFWQLSSLALRDGSMLGASVNVFSFAQIMHGDPMSLYVSLAGLLGVALQERIDPALTILLFELGFRNRLTIAKWLPLTTKRVVGYAESDYLLGIAKIPVELEGFSPFGFWSTHHLVRNASAIGSCLFPVFVTFAIIGVYAVIRKVYRRKYPSRSMAYSSRLTKGSSLMSEGKGIKNPFTMFEMATGAELQNRVGIICDYDNCVYIKGLRYATADGIYCNGFVIANNQWLIRTGDLWSILLIIISGLRLRDVFVYEVKDHKVSQTARLVFPTTMTVHDLVRLNTTVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP78</accession>
    <name>A0A8K1FP78_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP78"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="111" mass="12042" checksum="38E4F02D2A97F25E" modified="2022-08-03" version="1">MSTERKGAEMDRPRESEEKTETDVELLPNAIQVGNVQVVMTTYARGNGENEGGQSSGDSASTKRKASSRSPPSNQTELGDAVTVSAEELKKDNDDDDSTENKLRLPTIKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP83</accession>
    <name>A0A8K1FP83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP83"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470352" evidence="1">
        <location>
            <begin position="21"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="16824" checksum="985143FBF02EAC14" modified="2022-08-03" version="1">MQPLSTFVAFIALTVPTVTAHTPINGVMYSQPSRGLLQHSLCLDGEGCMSLHAFESTDDAVHRALAVMHTKTNKTESTHLSKLASTPNSRSTHGIICTGPMQTYCYHYRRLEATDEDEDDDEEVQEQIQQAQEAKKLKCERHLWGFVCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPE2</accession>
    <name>A0A8K1FPE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WDR19 first beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPE2"/>
    <dbReference type="OrthoDB" id="10250638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057855">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040379">
        <property type="entry name" value="WDR19/dyf-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920">
        <property type="entry name" value="OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920:SF0">
        <property type="entry name" value="WD REPEAT DOMAIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23389">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="WDR19 first beta-propeller" evidence="4">
        <location>
            <begin position="18"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="446" mass="49006" checksum="095E14AA2A0623B9" modified="2022-08-03" version="1">MLMVFSVDARHHGTGPVKYAWDPHGNYVASTGNSRVAHIFSRRGKLVDQIVPPSPSPCTLLEWSQNGEILAIVQANSSALVLWEPKKIREHQLVDLPCKDVSFMKWSKASGSQLLALGTNRGQVYIYDHSTGEKTQAVSKHKRRILCGDWNMENKFAFGSEDRQITICLPNGRTFDQVKIKSSPQSITFGGKTEDKDAILSVNMGGKTILLYDLNERENALELAFQARYGSIVAYQWFGNGYIIAGFSSGYVVIISTHLNEIGQEQYCAKFHEHSLREIAYNDENGTVATCGDNCIKVVRMSDWKEIAVEYLESDVSSTSSTPSAVGSTGVFTASSHDGAPGSGGSAVPVTSLSFEDLQWTSDGRILSVSCHNGCLHNFMILSSTLRSPMFDSDSAVMAVFKPISPWAMLFTVVFMIGMVLLLASTYFEVTVWDLVRAMSGFVEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ37</accession>
    <name>A0A8K1FQ37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ37"/>
    <dbReference type="OrthoDB" id="65235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="40078" checksum="81AACA223F42E5A0" modified="2022-08-03" version="1">MSVEPSVATPPDASELTCVLCRGKKSSEALSKVCHVCGLPVHGSCAQQVAARDCGLGFGFPPPSVYCSKRCYEGDLLESNGSNAGSTSGDALFASGNAQNRWSAEVPNEISATLTLKIGDVTKTSRRQLCITSFQFLLTEGFDVFKAKVNSRTNKELSIFSGDVHIREDPAIYIRPGVHSKQAELVPLTEANFETRIRKTYRNFLKRKALQGPSAGQERFECDIFTYVKKESAIRRRGGPAKTFAGLTANAFQLPIHPPGRTAFSDYSDTSVGNSATQSATGDISTHIQSLSHLEAIGHCVLGAKRRIAQLTPGDLSEASEHPSAYKNIRMVLNGSVVAVKVNVFDLLSAIDGAIGVGIGDDAASNSTTQEAMNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQI0</accession>
    <name>A0A8K1FQI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Double-strand-break repair protein rad21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQI0"/>
    <dbReference type="OrthoDB" id="10071381at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.580:FF:000005">
        <property type="entry name" value="Double-strand-break repair protein rad21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="5">
        <location>
            <begin position="533"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="66432" checksum="6D8CCFDDFE9DCC14" modified="2022-08-03" version="1">MFYSQIVLAKKGPLGKIWLAAHWDKKLNKQQIFTADIQSSVDSIVNPQVPLALRVSGHLLLGVVRIYSRKVKYLFSDCSEALVKIKLAFRPGVVDLPVNNQQASAHAINVSNFGEFEAELTYSIDAITAPSLDEWITASSQTVARRQDITLAEPLERVQEEDELAERDGFGFEDSFGGGEWQAFDLEADGGFGDAGRFSTSFVSEIEVGRDADTSIAPVLDDSLITRRFDGDKSIMDDGSQPGFEQPDLAFDNAYDDLPVDPLDVENPSINVEDPSLNMSADLNLSMNNGSRTSIDFALVNEEEEQANKAPQRKKRRIGRDTVTELSSAVLKRGMTDVSDIVRPREITCKKAKTGHHAFTYTSSAGLFSRPSKTDMSEDVLGMFKYTMKKRKFPFDRSRAEKEGSEDGDIEQTRRMSEVPGDLSHRDSMMMDDDGMLDASRDKSFSLGEAPSVNGEFDVPDFDYGAPLEPDMPGDDLDDLNVDIELGAVNDLQASIDDTMDDDHVNFSTAQHKWHPHTVKVMKVLRKSLDDKTEVTYNQLTKNTQNRRTAAALFFELLQLKTLNYVDVDQSTPYGDIKISKATRFTDHIPAVDGDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSA0</accession>
    <name>A0A8K1FSA0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSA0"/>
    <dbReference type="OrthoDB" id="78107at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="40"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="162"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="50026" checksum="1CF297E2B1B8E633" modified="2022-08-03" version="1">MFVHLFGKPTEDKLALVCTPKDRDPAMLDVIVSRLQNVPFFQDFPRSILEQVAANLEYEVVACGKCFALGEEHPHNFYVLLNGRISVRRKFGDFASSVTTHHLDVGVPFGCTGHMVSSSSKLLADESSEIGILWPDSYDATIRAYCTDQNNQIFQFLQQLKAFRHFSTSELGHIIGISERKRFRKGELVLDQNESPQYLGILRKGTCLMYQDFTMPPLRGEAEARRNRQRNEDSNDQRVLPFHRLLARPDWPLGFHVDNRHRKKRKQGRGRRNALMEHHMTKHQTADMMLLAARASSTASLTALAAEERPITPHALSGPALITTLCPGAIFGEATFHDQQNSRSKCSIVADSVVEVLLFDHLRLQDMELSPDVIKEILQYAPEYMEEDQVLKHRAEEETWNEYKNLRMLEVSKTRWPESKKHLRVLSNGCSIMLNATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C280</accession>
    <name>A0A8K1C280_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013863</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C280"/>
    <dbReference type="OrthoDB" id="1738325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="5">
        <location>
            <begin position="16"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="185" mass="20618" checksum="44DD5E09D4FC4123" modified="2022-08-03" version="1">MSGSGRKSAYRKGVTKKVLYDHPEPRENEAIVRVVALRGSNLFEVQHADASKSLTMLPTKFRKLIWVKRGDFLIVSGGDGDITTSEGKKGAVTSIVEAILYKDQIKNLRAKGLWPVELDELAAQESASAKKTTANDEDEDDDEDEEEEEKSGGIQMVATDSLFVNRNRRRGVIEDEEEEEDSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C285</accession>
    <name>A0A8K1C285_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013867</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C285"/>
    <dbReference type="OrthoDB" id="2365484at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16494" checksum="A9EB1CC7F8DF85C7" modified="2022-08-03" version="1">MGIVKSGKVVVLLNGRFAGRKAVVVKTHDEGRGDRKFGHAIVAGIDRYPRKVTRAMSKKKFTKKSKVKPFIKVVNFNHILPTRYVVDIDLKKVLDDEVIANPESRIESRKTIKKVFEERYLNQTSIKSEKKAAGVSFFFKKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2C0</accession>
    <name>A0A8K1C2C0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2C0"/>
    <dbReference type="OrthoDB" id="156390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434363" description="Apple domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="6">
        <location>
            <begin position="374"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="6">
        <location>
            <begin position="494"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="566" mass="61646" checksum="DBBDCFAD08766DA9" modified="2022-08-03" version="1">MRTQWFALAPLALLAQAVSAQDNCPDVGFLRPSVVTLFASPSNDNQAVVLRPDCSYEILNVAPKSWDPSSTDLEASYKDIERIRSFPNVDRLLLIANHLTPSDFSRDIQMVDLLIGWNALTSIDGFKFPPKLRGLDLEGNSLSHIAKGVIPDSVTYLYLTSNKLSSLAGISMPASLQHLFLMFNEFTSLDLPEGILSATMDGNPLHTIEKAKLPSTLEKLSCVGCNIETIRGVEFPSTFAEFIVTDSKISNFEIRESDKDIIDNLGLDSSVIVQTECEDKEAEKVDINGATICVISDERFNIKYHGAPDQPPTTTQPPTTQPPVTTQPPVTTQPPVAGGPCGNQNDGPKPCVTGEYCQPWDQWYYQCRRLDDKCGKQETNIDYVAEDITSLSVTLPEECCDKCHATAGCKTYTFINSTPDGKPMCYLKKAATAKNNLAGAVSATIVKGSEPVCSTPSSAQCGSDRDAIKCCPSGQYCQPWNPDFYQCMEAPSKCSKPQTNVDFYGEDLATISGVMPWECCDKCAATAGCKAYTFLNYNSDGVTKCYLKKGSSDKRQGVGTISATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2P1</accession>
    <name>A0A8K1C2P1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2P1"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="269"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35739" checksum="1B64EFD50B537FB4" modified="2022-08-03" version="1">MKISLQDAYMTLDVSSTATEEEVRTAYRKLALRYHPDKNPSPEATTKFQELSAAYKRICDHNARNKRAPSNQFSPFDMFAGGTDSDEEDIEDFDLSFEEMLMMFQMLFGPPPSRPKASASRKGRLPRGRGVAKAAKPRSDSKAGPRVVVNRGGRRRKAPTAGYEDELDMMIFEQFMSMGMDDDDLDGMEADMVDEMMHLFGGGPPPRRFNQASSDAEEIEEVSDWEEEEEKEANQTENKRDQAKDPVPITVGAHVRVSGKLTGVVKFVGPVHYTKGEFVGVELTDAVGKNDGTIKGVAYFSCPPRHGLMVRPQEIAVVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C310</accession>
    <name>A0A8K1C310_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Argininosuccinate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010408</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C310"/>
    <dbReference type="OrthoDB" id="2561043at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000002">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000001">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000015">
        <property type="entry name" value="argininosuccinate lyase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="3">
        <location>
            <begin position="365"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="50824" checksum="8A63B9B1B711FB0D" modified="2022-08-03" version="1">MTQEKKLWGGRFRGKVDPVMDKFNESLSVDQRMWQADLEGSQAYAQALQRSGVLTATEAQQIVDGLEAIKAEWASQSFVVKEGDEDIHTANERRLTELIGSVGGKLHTGRSRNDQVATDVRIYLKSTIVTISAALKELIGASTQLAENHLELLMPGFTHLQPAQPIRFSHWVLSHVAALLRDAERLTDLTKRVDVLPLGSGALAGNSFGLDRETLASALGFSKVTPNSLDAVCDRDFIAEFMFWASMLMVHFSQLSEDLIIYNTLKFVTMADAYSTGSSLMPQKKNPDALELLRGKSGAVIGRLNGFLVTLKGLPRSYNKDLQEDKEALFYVIDTIQDCIQIATGVLATMTPHGDKMRAFLVTEMLATDLAEYLVRKGVPFRETHHVAGAAVRMAEDKRKALNELTFEELSSLHPQFEQDVMDVWDFDVSVERKNVTGGTSKSAVVEQITSIKTWLDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3A2</accession>
    <name>A0A8K1C3A2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sister chromatid cohesion protein DCC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3A2"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="43512" checksum="90A0EF2FA8C3CB9E" modified="2022-08-03" version="1">MATTSGATPQQRLVTATTYSTDKYRLLELNPDVEQALTTGDKVVIVGGSKERAVLCTSSKSFYLTKEDMSNLRLLTEHSKWEEGSGADEIVMKGSAGFHYVLQPRVPDITMLKTLLLEAPYKKPMGSSPSSSKRARLHKLYTTDALMAKLQASKQELLDMLEQLCAFEDAGSWRVLDPDYQMSVFGDILHAIVQNDWDFQAGVPLQQLLAAVDEPTAVVRQCCRVYGSITKDDNGEKRATFDCNKIAMFYAKQLFMDEKENPHHTLNLGASEDWQLDYFMEKWQMRVPEPVKVSVDMLKGIALLKTQRSKPTRLIYFLEDELPMDPKLRFDKLFEVQEKWTIDQLEPYISALVRPGVTQASLLVKFARSSRQANSNERLYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3N4</accession>
    <name>A0A8K1C3N4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3N4"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000009">
        <property type="entry name" value="Oligopeptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF83">
        <property type="entry name" value="LD37516P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Oligopeptidase A N-terminal" evidence="11">
        <location>
            <begin position="62"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="10">
        <location>
            <begin position="266"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="731" mass="82824" checksum="F5D76597732A3B5F" modified="2022-08-03" version="1">MLRGALLRSAVRARAPSRFNRTALWKRFSSTASPLVECIRERTLPPFERLEIDQIPPAVKDAAADYTRDLRALEEQLKTALPSVKWGDVVNPLEVQSDPLERLWGVVGHLMSVRNSEELRQVHDELQQLVIQTFTETSQSKTLYDAYQAVRNSSEWESLSRAQKRVIELSLRSATLSGVGLEGEVKERFNKLKLRAAELSTKFSSNLLDATKAFSLIVTDKQQLSGLPDSLLQYFSQSAREDGHEDATSEAGPWRITLDPPSYVQFMKYAENRNLREQLHRASITRASGGEFDNEAIIKEILSIRKEMASILGFRTFAEVSIAKKMAPSVDEVEKMHEDLRAKCLDIAQEEIRVLSEYARQRGQQEPLALWDLAYWSEQLKAEKYLFTDEEIKPFFPLDKVLNGLFELTSKLFGVTIEAADGEVEVWNKDVRYFNVRSAEGDKEIIAGFYLDPYSRPKEKNGGAWMNVCVDRSRLLGRPEREGLRVPVAYLICNQSPPVGEKPSLMTFREVETLFHEFGHGLQHMLTNVDYSAVAGINGIEWDAVEIPSQMMENFCYDEATLQSISGHYETGAPLPKDLFEKIKAARNYMVATQMLRQLAFGALDMHLHHSYDGEEPLFEVQKRLLSRYSVLPPLDEDRFLCSFSHIFAGGYAAGYYSYKWAEILSCDAYGAFEEASKSSDSEDALKRVGRLFRSTVLGRGGGQHPLEVFEAFRGRKPSTVPLLTQYGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C441</accession>
    <name>A0A8K1C441_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tubulin--tyrosine ligase-like protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008636</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-[protein] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60144"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143622"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60145"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C441"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF145">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="61824" checksum="8C37694286ECE50F" modified="2022-08-03" version="1">MQGPNQGELERLEERNDSAEAEAFFYLLVSTMDSASKPVLFFPYPCTVQLERPCPPGYEVRKIRAKDTSVRITYSFIKRYMYNAMRQVFKTANIKKLTKASSNNWNVFWGHHLKSAEYAALMSYQKVNHFPGSFELGRKDRLCGNLLRMRKKHPDAYRNVIPETYLTANEYEKQQFLQQFTADPHVLWVLKPPNLSCGRGIKLVTAATTPSSQLTKKKAYVAQRYVANPFLINDLKFDLRIYVLVTSYDPLKIYLFNDGLVRFCTEKYSTSKAGLKNHFGHLTNYSVNKKNTTAFQPNQDNEDDEDSFSSSKWSLQTFFKYVREQGKGAQLESFLESVEDLIVKTFIAVESKILMMTTGANPNGCELYGFDILIEGEEMKPWLLEVNVFPSLSSSSPMDKRIKTILVSDVFQTIGVPFQDANAALQQTEKDKKDRLLGMNRKNTKGEKKKDKKTLDDLIQSKGSTLELDDADLQILKEMEEEDHRKGHFKRIFPTASSWETYGALFETNRYKNVLCMRWLQSLEQNQRRRSTTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4B6</accession>
    <name>A0A8K1C4B6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008741</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4B6"/>
    <dbReference type="OrthoDB" id="412182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF1">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="48692" checksum="506EA7488125D116" modified="2022-08-03" version="1">MVGFPLLNDNLRVTAAALIAGGVITAFTLRTMLFPILQYRAANLMKKALAEANIVIGRDIIVHDEEIFLDWVNRGMLAIGESYMAKKWEAVTPLDEVLRRLLAQPTEKRRKLLKSWNAKLVGLSAHIFNYQSPSRAGIVGSYHYDLGNDFFKLWLDPHMQYSCAYFKDIEDTDLDGAQRLKMHMIAQKLKLEPGMRVLEIGCGWGGLACYLAKNYNVHVTGITISNEQLKEARKWAEREGVSHLTSFEYQDYRGMHGQFDRVLSIAMLEAVGYKNMDMYYSVIERCLKPGGVAVVHSVTSNTSRKIPIQLWILKYIFPNGFLPSLQQMMKFTERKLIVEDVHNLGPDYDKTCFVWNQRFQEQWKLGKIENPMKTQSNPEVFKRMWEFYLLYCCAGFRQRTLQLTQTVYSKAYFQRYDTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4D7</accession>
    <name>A0A8K1C4D7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_008887</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasmic vesicle</location>
            <location evidence="10">COPI-coated vesicle membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4D7"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="11">
        <location>
            <begin position="31"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="12">
        <location>
            <begin position="693"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="13">
        <location>
            <begin position="836"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="981" mass="108993" checksum="47E4C6A1DA5F35A8" modified="2022-08-03" version="1">MATTGGVTNERYCTVLLPSLIGADKALPPSQDEILKGLESPKVELKIKAVKNAILGLLHGEKFPKVLMHIIRFCSTQSDHTLKKLLMVYWEIAPKYEHSPEVAPGAQKPAPKLLPEMILVCNALLNDLNHPNEYIRGCMLRFLCKIKEREILEPLKDAVKANLEHRHSYVRKNAVMTVYTMYKNFGELLIPDAPELIERLILNETDAGARRNAFLMLFDCAQDRAVTFLMNTMDQVPKFGDGFSLVILEMTRKVCRQDPSQKSRFVRCIFQLLNSSSPAVSYEAAWTLVTLSSAPTAVRAAAKTYCGLLNSQSDNNVKLIVLDRLADLKKHHTKVLQEILMDIMRALSSPSIDICKKVLEIAMDLVSTRNIEEVVNHLKREVVKTQDKSLEKSGEYRHLLIQAIHSCAVKFPDVATHVVHLLMEFLNSDGAMDVILFVRAMCESYPELRERILQKLLISFSDISLAKVYRVALWILGEYSTDLGPVESDTSILEAAKTIFAALGPHPLATYAAPKEGTKEAEADDGVAYSKPVTKSVVLADGTYATETSYSAPKKVAVVEEESIPGLRKLILNGDFFLGSAVASTLTKLCLRATRANPGAAASGPLKNLIVESTRYMCAIVAYGQSKETKHDIDDDSTRRILMGVRILLDPQCSEETYQIITEECRASYRSLLETQKAQQAESETSEEPVTQADELISFRQLRGKKALGSTDIDIDDGADINRALGQDGANEYSGKLRHVHQLTGFADPVYAEAYVTVHDYDIVLEILVVNRLPQTLNNLTVDLSTIGDLKIVERPQPQTIGPLDQRTIRANIKVSSTETGHIFGTIVYDSTSGAEKTYVNLNDIHLDIMDYIQAATCTDSAFRSMWAEFEWENKVAVNTEITNVFEFLQHVVDKTNMRCLTPTASLGGDTNFLAANLYAKSVFGEDALVNLSVEKQEKGKITGYIRIRSKTQGIALSLGDRITAIQRGKDDQNKRKKVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C516</accession>
    <name>A0A8K1C516_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_006686</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C516"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="34"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW56676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="344" mass="40453" checksum="907A7F100299C77D" modified="2022-08-03" version="1">MSRARVYCDVNETRPREYWDYENLVLTWGDQDNYEVVRKIGRGKYSEVFRGYNVTNNTKCVIKILKPVKKQKIKREIKILQNLSGGTNIIQLYDVVRDPQSKTPSLVFEHVNNTDFKTLYPTLTDFDIRYYIFELLKALDYCHANGIMHRDVKPHNVMIDHEKRQLRLIDWGLAEFYHPGREYNVRVASRYYKGPELLVDMQEYDYSLDMWSLGCMFAAMIFRKDPFFHGHDNYDQLVKIAKVKGTDELFDYLTTYDLELDPQYDGILGTHTKKPWEKFITADNKHLVSPEALDFLDGLLRYDHQERLTAKEAMAHAYFQPVRDAAEQKLQHGEETTSVSDSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C581</accession>
    <name>A0A8K1C581_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD40 repeat-containing protein SMU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006332</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C581"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054532">
        <property type="entry name" value="TPL_SMU1_LisH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17814">
        <property type="entry name" value="LisH_TPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TPL/SMU1 LisH-like dimerisation" evidence="10">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="346"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="57658" checksum="CDFEA767B7BB1A6B" modified="2022-08-03" version="1">MDEVEVDARDAVRLVLQFLKENHLLQAMKALQDETQVQLNAVDSKEAFLSDLAHGRWDAVLQQTKTLECASSVLAALYEHVVYEMLEMHERSVAVQLLRGAAPLQQLQQTDPARYQRLEQLTQQSAFDAAAVYGATSKQARRAQLVELFTHHVTEVAPSRLLSLLGQALKWQQLQGHLAPGADYDLFRGAPREKTKDQADRVVRKTAGKIKFSKTSTPQSIDFSRDGHMLTSGSKDGFVEVWDFEKCKHRKDLEYQAKDEFMMHDEGVTAQAFSPDGSMLATGDEDGKIKVWKVSSGVCLRRFDSAHSQGIHSICFSRDSSQLLTASFDHLVRIHGLKSGQTLKEFQGHQSYVNMAIFSNDGSKVVSASSDGTVKVWDAKTCECLATIQPPNTKFGEEIDVVAVRLVPALQGSGSNLLMCTRTSAMYLLSMQGDVLLTYKTDANNEHEIGNFVDCSLSPRGKLLYGVTDRGYLLTFTLETASLEATLQVSNGSSLGLVHHPHRNVIATFGTDSYIRLWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6M9</accession>
    <name>A0A8K1C6M9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NELF-D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6M9"/>
    <dbReference type="OrthoDB" id="511287at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032021">
        <property type="term" value="C:NELF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034244">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006942">
        <property type="entry name" value="TH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144:SF0">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04858">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="904" mass="100931" checksum="9062DA0BBE7A509C" modified="2022-08-03" version="1">MTMTAVWSEHFTKDGRVYYYNRTTKQSSWEKPADFDGESTKANASDGDKKAAATTSAGEWEELWDPKNERHYYYNRTSRKTQWQKPEGVKIKPYVAPVATAKKEKTKSETKSSVESGTTSSAETEASEKGNNKEERANGAQEAREQLKASESAGVEKETVEKAEMVADKSAESQHTPAKKTVTTESHAKQTPQHVTSTASGSHGRKALELDDEDAGDDDGDDLAEGDASAHKKRKKKVKKEKVDIDTALRKRRRNENEKRMIICDDEDDAARDTIQEYDTEDGKEASRLLKEMAKTDAIMETNVLNLINGFLRTHSDSNGPEILVEKLSSSYRGHAQMVGLVASWLDALPVSKTALEHKIAFDVADDAVIESKGASWDPASDILYAHLQEVVTQHYEPKLVSNVLSESTAEPEWLTEMLGDRKWRRMLIELAEKHKTCNLLQYAIRRISEAGHHKEIAATANANAFFSVFNGILLDAFCRIPFASDEEAREDLSALKKICCQSAYSYVYAEELLCTFDNKLYLLQKDASDQSSHRAHYRTVRSKLSRVRFELQETAIEKFGAKIEVFHPLRRRHLYDANSRLSEAILSIVKTKKCSEVAAEALAKEYSSPSTAPPASHLRDPLVFRSLLDPLFNPSEPLSSTFSEHCVLLLAFAACAKDERSILQSTSGVQLVSLDSQELEKTKTALQEASTICRSDHTLSYNMNLTGVVEKLTAVMEVPLASMGVLHWLEVTCTSPAFFNSSLLHICFPSLLRILKASIKLHVAQWPIAFQVLVTSLRLHPDVNPVKALELKRESLRTMVFMITSGYVLPVLEFIFINTPELDQALLRNFIAVLFAQIAPPYSAKFVMALTKILTHPKIQNAVKSCPPECKSKLRSFVSYCKKNAGVLSSDQLQALVIAHEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6X4</accession>
    <name>A0A8K1C6X4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6X4"/>
    <dbReference type="OrthoDB" id="10264606at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="249"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="348"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="622" mass="69267" checksum="42C81FCEEC9AC580" modified="2022-08-03" version="1">MSDGDDGQPPLKRLRLTPVHDDHESEGNDQARLRDVASAMQNMEIPPIHLPQGLVYETPPMRAEASSASRSGDVVLPRDAETGGEADAVESMENPVAPGEDVVEPMDTAAMDESKTDNEEPIHQSARAIVNELAPTTEMDFADLERLLFVSFRDQLEPKVERILDIVKKHPHGSEYMRRLVRDEDETGLTLLMIAVRHGMMNMCVFLLDEGADVNQVNEKRPYALLLAAQKGHEEATRLLLQRGANAESKNMALIPAAHFGHLKVVQILLDFNADQNYSNRKGTTPLMRAAQEGRDEVVHFLIQKGAIASSANNEGMTALMLAAQRGHARIATMLIKSGSDVNTQTRQGSTALLLAAKRGHTDTVEALLTAGADIFLKDDRNKTAAETAHRRGHLDVFFKITVSNQLRLMREALRRERFTEIMRLSQLYSDGRAKLGPSIGNSTKLAELYDRTLTLPRPLLASIARFLPLCHLWERRLTYLHQEAASQPTQAVRHSILIMDEVLFNVGLGALDEMKLQTKLERSIPALHEMRRLSPSGSCGHLALLRDHSEFRRIFTDVCKPPLCPDLLTRLYRMADLQGVLNLYPGNNAILFTADVAQDVVAVLSELLKADTNWRRARTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C749</accession>
    <name>A0A8K1C749_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000119">
        <property type="protein sequence ID" value="TMW57694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C749"/>
    <dbReference type="OrthoDB" id="113736at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="27624" checksum="C22CA94F54976D8F" modified="2022-08-03" version="1">MGPSQASKDDIPCLTGADNFDVWKARIRASLNGKGILGYILYENYDDPTLYDDVESESNNSKVKPVSQEPDPDAVDYGSDEELDPRSSSSSSSSSSDESSSAKKRSSSKPPAVKSFAETKAAKQQKKLEAEQQKKLEAEKFKKKKAALRQQREADAFNSLIQRLDNSHVRLVKEKLTAYEFYATICSKYEGVDAHGNPYTIMGFLLNARFKENDNLLKFVLHYEDTFKALDDATGSAMEDTWKSIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7R1</accession>
    <name>A0A8K1C7R1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013474</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7R1"/>
    <dbReference type="OrthoDB" id="10610729at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="383"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="60045" checksum="10358AB6F984A21D" modified="2022-08-03" version="1">MSTRAGSTTFFQRFADAVSTLRAAHWNITAHMQFARFDVEQPVMPIPAELRSLGIPVIARFQCAPFMSADTTATTLPSNCSIANSNIEVYTGGRSSIEIQRYMLALPPREVLVMNSRAEVAEVVKSKPFVVLFVVGDEESQAFSDCQALAKLDIDTNPYLAVTAETLRADHSFEMFTPSSVPSMLLFREQGTRRLEFDKVWSRGELTRFIQRNRYYLLATYSPSESNYFFDRTATAHVLLFSEPKSSYHEALLAQVEDIAQSYYTAETNPSRIILRFVVVSDEEKTLRNAFVITDEQLPAVVVMDNVTTVPMRLDAMGEELVWEIKLRAFGWTLSYFLHDRFPPFMTGGVDDDGEPIVVTTPKAWWDYSDLFEEDLTVSSTTVTFTSPRPLVALDTTELGGNWMERALLETNPMAIDELSDITELVARWDNPENDERVLVLFYSPRCGACQDAMTVLEELLDTPPSRGFRLDRIVKIDVETVDLQDLRGEITLRLLPSVQLFLPMHQVVEYPSRVLRLDDLVEFLGLHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8D2</accession>
    <name>A0A8K1C8D2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8D2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="49512" checksum="0C24EC8EBECBC197" modified="2022-08-03" version="1">MSTQQSDSGLFVEEADDTELLIAALAFLDEDSSGSASAEDAFLSCPGIESCGSEHVHLTKEDDKTSPTHEGGDKFVTNEKKNRNAKKRKWRNAPKEELEQLRVAVEGLEARLAGLKRREDGSESNAMTTDSMWSQIADRQLKAREGSVRENARLRALLEEHVRTAKSLGRMLIKVQSTGEESRSDKRLRANGTSNPLDDPAYEATARQTVLDMYHEVDRIASDPRYQEQDLAPTFYVADLGANEEGRIQIEVLETRQLPFELDVTANALWDMWIHRHFGPLEAKDVQGIELTQDSFIRRFDGEMRTESERTRFAFKTVTRRFSEPNRVVTVAVIMMQPTFLNGRPSDGVYMRTQVWNIINRTTDTHGNPATRRLVYKLVSPEVFDTVGSISDREEDLHMLKTYVIGNAATGAESQNQVLENKLVESLASLHWSRYAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8X1</accession>
    <name>A0A8K1C8X1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1418" mass="162049" checksum="D5D9ACB167E4E329" modified="2022-08-03" version="1">MALMRSQAPIMRTTALFAALVETEWLQRQCLPLLTRAEAVLVVLVAVEAGFESLRRDKSAFPPLSTEALVRLAAEHGRWRVVQHLQRSCRPVKHPFYIDLGDEEALGPIGDVDFAQCLWIQRHHPLAFSASVVYAAVRRGCLEQVKWLDRFVEYDVNLAIPIAAQAGQVDVLQWLLDNQKPIKKHFWFPPPRFEVVMRRADTFLDGINWFDTKTQTTNSFLVTYGLLPPSRPSSFHKRYPFMDWAAERGDLPLLQRLHEDPDLKRTCSYCAMQSAAEHGDLEMIQWLHTNRREHRNLMVHVLQKAAEHGHVHILAWFEANGLMPRSSASIFRETARAGQVEALRWLFGHLDDAALHPPELTYYAARSGRVDMVKYIHEELDIAVTSQGVYSAAQKGHDEVVQWLLEHDQEQVFSTDDYYDMLLKAAADNGNLLLVKKCVEEYGVWSRYAAEPAVTKGHVSILDYLHSKALERATSAGTSLEDEISYSSVDLPAMLKSGKCDDIVLWVLKHTSEEDQLDKLDDISSLVAQNVPSWNFTRQYMLLRPRQSRKIRLLPQWAIQLGSLSDLQTLEAMQHPKLFTKRTLRIALTTDHLTRMACSDEQRIFLSSQAIFVNLIDDLTIFFLPTWTFRMAILPLLDADWFQRQLRPLLTRDDVVHVVLVAVEAGFESLRRDKSAFSPVSNEELLQVAAKHGKWDLVLRLQRFCRQMKRQFKAHLDGEKTLGLHNDVVLAQCQWIQRHHPVEFTSVVMYTAVKRGKIEEVKWLHRYIDYEVGDTIQIAAKACHLDVVEWLLDHHRSASKRNPIQDETTTRYEVLLRREDSFLDALSWSDNVSKTTNFISPIEGLLPPRLAGPFSKQYPLMDWAAEKGDLHLLQRLHGDAKFNLAYSDHAMRLAASHGHVEVINWLHEHRQTQENDYAGAVHAAVVAGHLAVLDWFHTNGLVPRSLRDSFEDATLAGQLRVVQWLFEYYDDPAIRPRYLAYPAVRSGSLDMVRYICQEQGYGVMEMGIHAAAKRGNYDIVQWMIEYDREHGLSTSSSYAMLLDSAAEGGNLEVVKWCVEELGAWSRGTASTTAALAGHVQVLEYLYTKAQERAVLHGTSLQEQLSCPYLRLVEMLKAGVGDEAILWVLKHASDEERGWLVTDKPAFVQLCTSDSPNAPSWRVMQQLMTYMPELCCEIDLYPLWAVLYGTLSDCQALEDIQHPKLFNMSTLNHLLEHSRDDVSMTWFVARCDSRLLDVRVASWAAKYGAVTLLPVVVEKLLVQGEDLLQVFGTVIWSAVKHDQVSVLDWMSRQAYLRELKEQLWRFSLAERAARLGHMRSLLWLHQHQKVDRQQMDVLAGVAAQWGQLQCLKGLYTAQGVKCTITDVVKAARRGHADVVKYILHQQPSTQPIGKEERLEVDGVRYHYELFMAQVCSSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAE6</accession>
    <name>A0A8K1CAE6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAE6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="323" mass="37190" checksum="B0A8FDAE5132B6E8" modified="2022-08-03" version="1">MMRFIRTMEEFRDDAITTAPPGKKHRTMAISEIIHVEPLHEQVEESNHFSSITDDEEEIETIECTRSAVVDAPVKKTPPPMPLQTYIHLNADPAKRRKTLESLRPMQLAMARRFIRDRSRFLDLAERHNSIEIVQTAVGGDQTAIQFINEPFTQANRTVREVFDAVLHSSLNIEKALAEANYAHDTVREGGIWNDEEIAHHRLVCSTDEVREDGEPLSIDSNSVSLTEYDPVEDVGVMVVRYVDHDELFPYKPRERLRRDVVVMLLVSQEDFGVVLRAWVSTRQRRSSYFKVADDAMERLRGELGQWGSYQLHSVRERLGVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAS9</accession>
    <name>A0A8K1CAS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED4</name>
        <name evidence="9" type="ORF">Poli38472_007167</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAS9"/>
    <dbReference type="OrthoDB" id="1929813at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="39670" checksum="D3EE7889ECF1B41A" modified="2022-08-03" version="1">MPSVQDDVQVFLHEHRFLVTKLLESLNTASLPPSTITSTRLRAVNDTFNRVLEKDRDLLSAVKTLVQHQVAQKELLAVQDEIHEKKQKVVRYAAQLRQSQEDIALVLKKHRRVLDHARQKQKVLLDPRDVVAYAHRIAGTTSAPKEWRPGFPMFGFMPPAPQEQMMRAGVLSRGVVDEVVTLEPESSAYSAQSDAKKTEEVDAAKLQGIPIGLGATEAGIRKQMPPGWKPGDPVDLPLEALLHYMGRTSLAEHGVTLPESWKTGDPLPPEAMEILRKKFKIPEKRSALYEDDVVDDVETLRKKRRLDGSETASDTAEDDSSSSSSSDDDSDSEKESAQKITLSLSSDDDDSDDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAT6</accession>
    <name>A0A8K1CAT6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAT6"/>
    <dbReference type="OrthoDB" id="9992527at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF3">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="13"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="331" mass="34990" checksum="190094ABE71D839C" modified="2022-08-03" version="1">MPSFRAIQVRQFSTNFRAVTSIVEVPEVPTPAAGNVIVQNHYVGINASDIQVTNGVYGNPELPFTCGVEAGGVVTAIGEGVENLKVGDSIVYQKLGAFAEYAETSAATALKVPSPDPTMVPLMVSGISGTVAIHEVGQMKQGGENILVTSAAGSTGQYVVQLAKLAGNHVIGTCSSDAKVELLKTLGCDRVIVTTKENVGDVLQTEYPKGMDIVFEIAGGEAVKTAVENIAVHGRVILFGFMNGGEGSDPYAVNQLHPMLMSRSASLRGFSVVNHYDKVPMYLERLLTLIKEGKLISSVDPTPFTGLEGVADAIDHMYARQNIGKVVIKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBM5</accession>
    <name>A0A8K1CBM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBM5"/>
    <dbReference type="OrthoDB" id="183992at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="61200" checksum="11E8824D30E43EE3" modified="2022-08-03" version="1">MAHMSKRGTHSRLDHVNALETVWLPLVTCLSFEDQLALLVYAYDDDLDELAVYLESQQRFPRDLVMDVAVAHGCVRTLKRFLRVEDVRLSPGLAHATTIYVPSVLNNRTCVMRWLNRYRPRVYCEEAMMMAAQRGDLELVQWLHTTCVYDVEAAMCSAAKRGHLGVAQWLGDNLSSALPTGSKKSIAVDVEILIRLYSAVSDGRVLYWAIRRGEDITRWFCVRHDHGEEPALVQKSTDGAMCHDALVMDALSFAVSLGDKQLMKQIYADKTLRPERTEALAVAARRGDLAVVQWLRSDCGYGIPLRTMVEAAIGGNTALIEWLHESCGISPDCYGMLYAGCKFGHLEVVQWVCSHCPDLMLDPVRWAQACCPELKQKELQLVQNRWVEWNLAEAYRMIDQSGESAERVRQVLEWLLSVYELEIKRESGQLMLNVAIACGSVTLLETLPLVVGYHEQGMAFTLAGELGRMDVLTSILSRLRGRNEIEQFFRQVSKTGSREIMEVLLRTHPQYCNFMPSRGVFNLVRKGHLEMAQKHHRIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBW1</accession>
    <name>A0A8K1CBW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBW1"/>
    <dbReference type="OrthoDB" id="151972at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="360"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="59769" checksum="ABB0520D128B994D" modified="2022-08-03" version="1">MSSTTHSASGDCVRFPLEEHVVPLVRIASNRVEDWKTTAQREVEGVLRNPKSWYYRPNELKQTYRSVYEKEAIRGYTRAVPNSSLKDMLCLAHLAMTLEDVVYGLHAVTTNDQRAIFAQLYEDVLLDAAVLRVYEGQTGTDPFHFVGLKWLAFASPAPNMVKPLDHVYFDYSGTTVDAMGRQVLFHYRRSFPLQPEELVHERDLGLLRSSYYQFGLYRIEGGGVLYQCIGCLDIPPEVPTWVHTRALSGEFNSTKNLADLAKSRAIALTGVLRHPVPSAAADNGDHQKMCLECDKKFNVLRTRYICRACGGAICKHCITGLTFFNEESQFMAAPITLSAKFCSFCVKRAREQPAIEHLVTKMGKTSLSEPSRRRHGSHLKTGSTTPKISAENAQIRALRESIEREVGRSPSQSSSPLEDTPAGVARPASLASSVDSDSPMGSFKTKPTPQSKEVFQQMNQAIRQQEELLMTIQKERAKLQARHNSAPGYYSPSAYASAAALPQEYLSPLPQRGAVLLETSSSPSRIPDDERFEELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC21</accession>
    <name>A0A8K1CC21_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC21"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000014">
        <property type="entry name" value="Ribosomal protein L13, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16098" checksum="8E78A7DAE3170D22" modified="2022-08-03" version="1">MSTSKIAQASKVAWHVVDAKGQVLGRLASQLAPILRGKHKPTYAPNVDCGDYVVVINAKDIVLTGDKWDQKLYRWHTGHPGGLKQRTAREMFERKPEEVLRRAVFGMLPKNKMRKLQDAKLKICLDENHEFVEQVGENPVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCD1</accession>
    <name>A0A8K1CCD1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCD1"/>
    <dbReference type="OrthoDB" id="151784at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="56894" checksum="343D3E88DE2EED77" modified="2022-08-03" version="1">MPLTVSFRGAALCRTPSSKTPVTTTGKPRAHPEPYMCDFFENIWETSGRQDEEPEEKSNFMSMLKGVRTLRRRRHHERKPPLIDIAQVAHVLTSVLDYRSDYPPLSTEQVNIWATRSSTSESVGSTFSDEHPISHNIVSPIQSQKFPSVPQSAPQLRHSMIEDNAMGEPEDEDSPGGGKLKVSDLARSTSIEIVKNELVKDKKEANNDFMFPLGVDVAVPPPSSKNGSVVFSSVFLEKQKWSWSIRFLLGIHEPIRHALYVMDRFLEQSQQHEEIPTLERHTREFFAWFTTYFVEFLKCQHDIKARVLHPLIKLKYSTKQEILRTYDEIHHILSQIQLQEHALLSNNRVKLDRTVWLKRLDTLQKAIRRLNMTLHSVLNLEEKTLNPALSAAFTEKTFRSFVLPRLFRAVKEKKVIVPWIVERSKVWGGEAEQQSIQSMLPFSAKFMYKKVWRPYFVSNIASAMKHLNEFELNASAYQPERREEQHFGCVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCT4</accession>
    <name>A0A8K1CCT4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000690</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCT4"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="117" mass="13591" checksum="D6847488C49F83C1" modified="2022-08-03" version="1">MSSFKKEHPFEKRQAEAQRIRSKYPDRIPVICEKADRSDIPDIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFINNVLPPTAALMSNIYEEQKDTDGFLYITYSGENTFGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE52</accession>
    <name>A0A8K1CE52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE52"/>
    <dbReference type="OrthoDB" id="92924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="45735" checksum="BF1F10CBCC3AA6AC" modified="2022-08-03" version="1">MPSLKLSPEEQHAAIDEIEAVLAETLVHEHSFRSGATAIDKKRWKEVKVHEGFRVYRERDPKSAQRSFMDRASSIIAPRFVSIREAPAMSTWTTDSSEEDAGYVANIKDPKVPMIVATGTVEGSLEDVVFGALASDEVSWRLRAAYLKDKTTDSKILSTIIEPTEEDPYKCLCIKWFMREIPVFLSPFVLPRDLLVMEATGIAEDEYGERYGYYMLHEFRHPTLPDFNSRKIVRCGISHAYLCRQLRPDKVQIFSRGFVDTRGDVPQTITVQITAETTISAANTVETSYMKKLGWLMMRAQQRRLYEKRPPAIPRTICSCNQSKTSSLLPCQVCGESFCSRCTVHRKIVVDMTADELIERVLPFCFGCVLTAKQMSPHEVAVDTVVRPRAYLQKTVEPADKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEB0</accession>
    <name>A0A8K1CEB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEB0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="537" mass="60089" checksum="DF4E860DB8ECE8A8" modified="2022-08-03" version="1">MARGARGKSEWLQDPWLLDDAIKSCHLDVAQWVHLSYRGEAAGTVTTKSLHKAASEGAIDLLQWALTTFPDAQLTTDAMDGAAANGHLETDQYLHSERNEGCTTAAMDKAAGNGHLAVVEYLHTHRQEGCTVRAMNNAAGNGHLHVIKFLAGNREEGCTDKAMKEAAAGGHLDVIRLQPKIAVYYAASNQIDAIHCLYKMYSFFAVRGSAIVAAARHGHLSVLKYLHKKRQRRPCKVPLLDIAAEGGSLDAVKFIHEHCPIERCTTEAMDAAAQNGHLDIVRFLHQKRSEGCTVKAMDEASDEFTVLRFLHTHRREGCTTAAMDAATIRGNLKVVKFLHENRKEGCTTNAMDHAAMNGYLSTFRYLHEHRTEGCSKRAMRLAIEIGNFLVVKFLHQFRTEGCTAAALDTAVLCGHLTIARFLSENRTEGCTKHGFDWAIRSGDLDMVRFLHENRHEGYHEAVLEKAIARDPEDTYLVQQLLRLNELKDTLSRRRFLEKLKFERVFKEGRFAPKRRAEQAEDAYDSANESEEWGAELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEJ1</accession>
    <name>A0A8K1CEJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEJ1"/>
    <dbReference type="OrthoDB" id="167254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="184" mass="19706" checksum="E9E0B07047251931" modified="2022-08-03" version="1">MTEATPPNATMEAAMERFLADFDPLAALEAEYNAVLAQESRLQPQAEEQAGENEDEDDDDDDFGLDASYALLPSSPGGGNGGLFDEDGESEHGSEEEEVAVKDSTTEKTTEQSPAMDAAAKETIMTSMQQLKLAPPPWAAERLISDQELVEMVQGRLRLSTTEAQHAQDSKASDELPSSIANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEK5</accession>
    <name>A0A8K1CEK5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEK5"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000753">
        <property type="entry name" value="CAMK/CAMKL protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="31475" checksum="9CF7A2804EAD3786" modified="2022-08-03" version="1">MLNHQYQVQRCVGRALYGDVWLCEDTKRDNELVAIKQVSLVRAKRALTTHRHMDNPFDERKTAVYLMELNGHDNILQFRHEFLENGSWFMVMEYCEGGDLLSRLQDVPENRLDESVALHYFRQVIRGVNFLHGSGVAHRDLSLENVLLKNGVAKICDFGLSTEANRMCTERVGKAYYMAPEVVSGESYDPLAADMWSLGVMLFIMLTGSPLIPCASRDEKAFLALEAFGVEKILDAWGFTSSISAGALDLLTRLIQVRPEKRLTIEDVLEHPILNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CES2</accession>
    <name>A0A8K1CES2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009584</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CES2"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006218">
        <property type="term" value="P:uridine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17763">
        <property type="entry name" value="UP_hUPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010059">
        <property type="entry name" value="Uridine_phosphorylase_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01719">
        <property type="entry name" value="euk_UDPppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF11">
        <property type="entry name" value="FI09636P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691">
        <property type="entry name" value="URIDINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="3">
        <location>
            <begin position="42"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610059-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="31839" checksum="011BA1D2A9B86097" modified="2022-08-03" version="1">MTHVANAHIQELAADVLYHLGLTYDKHDDGKLAKLFGDVKFFVTGGSADRMSKFAKHAAEALQIATPYGYEIAPIGSTSRYVIFKVGPILIASHGMGQPSVSILLHEVTKLLEYAGVKDAIYMRMGTCGGVGVAPGTVVLTSEGVNNKMESVHYVDVLDRTVARASICTPEVTEGLSAAASQLNYAYAVGKTLTCDDFYEGQGRLDGAICEYSLDDKMNFLRKAAGAGVKNIEMEARGFAAFCHRLNIPVGVACVALLNRLEGDQVTSTHETLKGYEERPAEIVLQFIKNKLGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF48</accession>
    <name>A0A8K1CF48_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF48"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046351">
        <property type="entry name" value="UTP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="175"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="649"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="737" mass="81616" checksum="D53650849A496F35" modified="2022-08-03" version="1">MRKPSTKRAPENGVMNGKKRKASVDEREPAVPNAALRVHRCRFIDWMPHAVHVMSFNPTGDQLAVARANGDVEMWQIVARKWHLKYVISGSTQSKISAMIWSQSNRLFVASFDGTLWEVDLESLRKKNVVDSNGGPIWCMDVNNETETLAVGCEDGRIRLFSFQNDDEIYFVKGFVSTNRRVVSLAWHAGANKMFSGSEDGIIHCWNAVSGRNESRITLETLAKQKCVVWSLLVLQDLTIVSGDSHGHLSFWNGHTGTLLQKFSHLTADILALCVDSNNSMLFASGVDNQVAEYRRVGESEGSWSYAYSHRAHSHDVRAMALSSAPRPVLVSGGIDTQLVWYNANSFNTSRPFKIASMPYRKTVSLSSEKRVLLVQKSTSLDLWRLASSETSSAIVDTTATPQHQLLLELQVGSAHNIACSALSPNGEFIACATAQELKLFSLDASSGFQPRKLTLPDGIAKESARVVAFSPDSTRLVIATATQKLRVLDVTKIEVLKTFNLVNSSSNDATDSETPAAPVLSLSISLDGQWLAVGDASNQLSIYNLDSMQFYCHLPRPSEMHTNMGFNPSGKLLVVTLVSNSFVCYDVEKKALSDWYRQHHERFPKAIVEGRNIKGMAFDPAQPDFLYLYSQSSLYQINMSDRCNSPKLPATASNGPASKKVARRARAPSVGAESDRVATDDDLVDLEDGLCRVINRYRPLSFVDFVDAHELLVVETPWLKVLARLPGALQRHKYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFG7</accession>
    <name>A0A8K1CFG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine-threonine kinase receptor-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFG7"/>
    <dbReference type="OrthoDB" id="200206at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF13">
        <property type="entry name" value="SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="37636" checksum="2723C0127B8BCBEA" modified="2022-08-03" version="1">MSSADAPPSPSSRGALRQIPIVCPGHSRPLAEVQYSPITSDGTFFLISACHDKLPMLRRGDTGDWIGTFEGHKGAVWAAKLDHKVQFAASGSADFSVKLWDANSGDLITTFEHKHIVKSVEFTPDDSRLLTVGHEKLFRVYDLLSIKEQFETYRADGRTGIVVMPTPPVAQMTTKEQIRKVVVLNDHVAVTGEVDGTLTVWNLHTYEKTSEFKVDAGVMDLEASRNGTVITVAAGKKVYFFDATNNFAPLRSFQMPISFGEEGGASLHPRDNKFIAGGSDTWVRVFDFESGELLETHKGHHGPVRCLRYSPTGDSFATGSEDGTIRIWQSDSASAAAASVSDVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFI8</accession>
    <name>A0A8K1CFI8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Temptin Cys/Cys disulfide domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFI8"/>
    <dbReference type="OrthoDB" id="166578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057626">
        <property type="entry name" value="S-S_Temptin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055313">
        <property type="entry name" value="Temptin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737:SF2">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24784">
        <property type="entry name" value="Temptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426064" description="Temptin Cys/Cys disulfide domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Temptin Cys/Cys disulfide" evidence="3">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="22848" checksum="5BBA41026E7D7D55" modified="2022-08-03" version="1">MKCIAAISTVAALVASTDAMASFSSKFPNGDILFEQALGHTADMKLTEFGTAFKAAGKEWTKAFCEAKFPGTQITNGAAFGDPCCTWKSGPAPQKVTKWSGKPTEGKECASKGGAGAGAGASTGAASKAPAAATPAAGVEDDYSDDLAPTPASTPAPATTKAPAVAPTPAAISDDIKLDPVVPVVAPAVVADSALSTTDTTSASLSSSGNSTSTSEKDDCTVEDEEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFN1</accession>
    <name>A0A8K1CFN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFN1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47725">
        <property type="entry name" value="OS03G0364000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47725:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="114" mass="12692" checksum="A7E75122D14CA0BC" modified="2022-08-03" version="1">MASTGERKFVPYIRVKRRNQTLFVDAQPGDTFLSVKEKLGAVFQLPASSIQLWSGLNQKEAKELTDVATLADHDVQNDSVVYMCWKKEQSDQWEELSVTKIDALSGADSGAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGR0</accession>
    <name>A0A8K1CGR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGR0"/>
    <dbReference type="OrthoDB" id="186607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="223"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="464"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="724" mass="79568" checksum="44DF265D8A8B6C81" modified="2022-08-03" version="1">MASLPRRPAAAARAGRAIQVAVNHFRVRVDTGRGDINQYDVDIEHATPRAPVDGQRRPPSTLQSALRRRVIRAMLALAPEFESVAAVSGEQRLVFTNGRLNQDHFVVRDVVPTGSTERGGAFHVTVRFASVKRVAQLDAVFAGRLDVTPYDVLQALDVVMRHTAVLRLELVGRTLVNPMSGNRQSLGGGVSCVTGYYQSLRPTQSRLTLNVDRAFACFYESKPLIDFCQEVLGIQGALRPPLTHAQTRTLTDALKNVRVDVTHRQGANGGRLGYRIDSVTGLSAEQQTFEDENGREQTVAAFFAAQYTSLQFPKLPCVHVGVVNRKVYLPLEVCFVSGKQRVRAKLSGRQTSSMIRFACVAPQERKRVIETALREDARFQEDPRLPAYALTSWSVIDLCGGRLRDQKLNRFLLALCRVLASMGITTPSQLPPLIRPQRRHEPVRSVLTRAVASARSRFSSPAQLVLCVAPGKDAALYGEVKRAGDVELGVVTQCCLLSHVEATKDAYLRNFALKMNVKLGGINWVLQEEEGRGTGGRGAPPRALDVTNEPTLVCGADVSHPSPSDTQSPSIAALVGSLDRFHATHTAIYRAQTHRVEYVEDMEEMMGELLTRFETSRGVLPTRVLYFRDGVSEGQFGMVQGDEVGAIKRALQRKTANAANVRVSAIVIKKRHHTRFFPMRRSDSDGMRAGNVSAGTVVDSVVCHPQELAMQVSKAPHAHVTIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGT7</accession>
    <name>A0A8K1CGT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGT7"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42235" checksum="6AB562DA6AC79AB6" modified="2022-08-03" version="1">MRSPGKSPPKSPSLQAILASNVTIANPREGTQLAEAAPQLDLPQRIDAPDSIKTPPRIFAPTRDDRVRKTTFSPHATALHKLRHQIRHSFENGDELVAKLACCSTQKLREKDTAVSAKLTKEYTMLAESSKRAGRHDAECTAHLCLGIIYDNVEDYTKAIECYLLVLSISESTQQKLFTALAANCIGVNYQLMSCGTKEYTYTGKFVDAGNRHLQNALVYHQKHVEAGDDAGKFVAHLNLGLTYGSLGDPNEAARHHQEALRLSIRLNSAYGQSLAVGNLGLLASRQNDLETATACMEQHLQLVQSVNDRSSEAFAWIQLGLLAGRTGDHDKAVRAFDQAYKIAQEVGEVGTVKQCSCYLGIARARLQMVAYVKHLTASLVPQPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGW2</accession>
    <name>A0A8K1CGW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGW2"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000286">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="26113" checksum="7F17A40A6AE262A5" modified="2022-08-03" version="1">MVSVPDAAMTRTKEAAPFLKSLRRMLDTESEAVLRWTSDGRAFEIHDLEALTAHVLPKYFKHSKYTSFQRQLNYFNFRKWTKSRASVCTFSNTYFVRDDPELAWHISRKKSSPSSPNKPALSKTTARAKNIHIAISVPSRGSSGRSLFPFPSPTDVATTQGRDQESQFSESCWFSRNDMKLEPTVAPASLDWVDTLYPSLDIVSRYAEIPEFYSDYAAASRDGQASIMQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHH3</accession>
    <name>A0A8K1CHH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">maleylacetoacetate isomerase</fullName>
            <ecNumber evidence="5">5.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002610</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-maleylacetoacetate = 4-fumarylacetoacetate</text>
            <dbReference type="Rhea" id="RHEA:14817"/>
            <dbReference type="ChEBI" id="CHEBI:17105"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="EC" id="5.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.2" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHH3"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000017">
        <property type="entry name" value="Maleylacetoacetate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000041">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="GST N-terminal" evidence="10">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="11">
        <location>
            <begin position="90"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="218" mass="24587" checksum="B0DA80F382CC4873" modified="2022-08-03" version="1">MTKPVLYNYWRSSCSWRVRIALTWKGVEYEYRPVDLYADGGEHFKEEFTKVNPNQRVPALVIDGHAITQSAAILEYLEEAYPEKPLLPKDLIQRAQVRAICMIIGADIQPLQGNNAVMSKAVENVPAEEQDAQKNAWGKHWVQRGFTGLEQELARTAGKFCVGDAITMADLFLEPQVYNAHRFGVDMTQFPIISRISAELSKVPEFQAAHPANQPDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHH6</accession>
    <name>A0A8K1CHH6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHH6"/>
    <dbReference type="OrthoDB" id="155500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="42738" checksum="E2F90A8FA9FC1103" modified="2022-08-03" version="1">MEELLTHLDDDFVIHSTQLPRLSPFPTWNGVVASTTDGRVSLICESGDVVIFALRRSSASSPLSLSNASDQVHAQVLSIINSPRKNVMSMCQCWTKDGSHLVVARDHLVIIYRIQDAQVSVRATLELRVAAASVDVVSDEHGSLNMIIGTVTGVAIYAVRALYTEHVHMHTQVTPVLVRILHPEVPVSVVKASPDHQFVAIGSVDGRVMLLRTQDVLAGVSNAPVYAKVLASPRVTSITFSPTSSSMVISTRKGNVYIVSRSTDGGEWLLDPRYAPLTENPKLKAGSISTQTLTCWWNSTLDTSRASPVFIIAARSCATELEMYDTTSSKKMHSLEFKRDPQSSSPLAKAADDTHIVGITCITNDRSVAQLLCIDSDAHVTLISWPFLEQYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHY1</accession>
    <name>A0A8K1CHY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHY1"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="28104" checksum="645206AEB218C218" modified="2022-08-03" version="1">MDLYADLPLAKGASTALDADGKPKNPVSVWAKGVPVAPPSAGRGKVFVPPSVQAGGGNSTTRAKSPSGGVSFAFKPASIARKANTSIKSTPANAFSAPVTAREPSPKTETQSVTPTQRTGLGFVAATTWTQVTVQKENHPSTENAAASAGESGSHFFQVTYRDEYHPSRPNSYEAFCDERTAKEKMEQVKRDLERRQREQDKESKREREQLLKDVVEGKASSVPLQASAGRGRGMTVPAWMRKKIIWLALEKLTTTFKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI43</accession>
    <name>A0A8K1CI43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="8">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002081</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI43"/>
    <dbReference type="OrthoDB" id="2020662at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000036">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000003">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="578"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="714" mass="79911" checksum="CFAE127F5EC6F75E" modified="2022-08-03" version="1">MSALVTVATCNLNQWALDFDGNLERIITSIREAKRRGATYRVGPELEVCGYGCEDHFFEPDTFFHCWESIASILASDETDGILCDIGMPVMHNGVRYNCRLYCLNKKILFIRPKLFLADDGNYRETRWFTAWKVNKENKDQMLQQHVLPRNIQKITGQVHVPFGYGALSTLDTTCSSETCEELFTPDSPHINLSLAGVEIISNGSGSHHQLRKLHQRLELIRGATTKGGGIYLYANQQGCDGGRLYYDGCALIAVNGEVVAQGTQFSVKDVEVVTATVDLDDVRSYRGSISSRSEQASALKTVLPTIHVDFSLCHDEEDLSAAPTRPIDLHYHVPEEEIALGPACWLWDYLRRSGGGGYFLPLSGGADSSSVACIVGVMCHLVTEAANGGDPQVIRDVQRIMGTTGEEYKPLTPQDLASHVLHTTYMGTKNSSAATKKRASTLAQELGCYHLNMGMDTMVDAVINTFALLTGKTPRFMSLGGTIQEDLALQNIQARLRMVMAYLLAQLLPWVRSKNGFLLVLSSANVDEALRGYMTKYDCSSGDLNPIGAVSKGDLKKLLRWAAVKYNYPTLQTVVDAPPTAELRPTGNASDDDTTDHSQLDEEDMGMSYEELGYFGRLRKIDRSGPFWMYRKLTHIWSHLTPTVVAEKVKRFFFYYSINRHKMTTLTPSYHAENYSPDDNRFDHRPFLYNARWTRQFRAIDSLATKLEEKKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CID2</accession>
    <name>A0A8K1CID2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CID2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="90" mass="10345" checksum="B36E3296E084CC13" modified="2022-08-03" version="1">MESAMETSLLELFAEIDEWENQQALLADATADKPVTKSKRTKKAADPEAKLAMLPLPEQSDLEGKERTRLIVKRYYYRKLVRAFTEEKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJL6</accession>
    <name>A0A8K1CJL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJL6"/>
    <dbReference type="OrthoDB" id="10266805at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987:SF1">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441613" description="PhoD-like phosphatase metallophosphatase domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="51671" checksum="3F9241473E2F6387" modified="2022-08-03" version="1">MRSMAMLPVVLAMTSMTTAQGRMEQSNALVDVEAIALPLQRVAFGSCNHQDREQPLWSTIRAREPQLWVWMGDAIYGDYKAYDEIRTYLPPFPTFRDAPPEMLVEKYAKQLGHPEYQELRARVPIIGVWDDHDYGLNDGGKTYKYREASQQIFLDFLGEPPGSSRREQEGVFASYTIGKDGQAVKFILLDVRYNKDAYEDARGDFLGEKQWQWLEDELTTSTASFHVIVSGVQILPDDRVLPGENWARFPYQRRRLLNLLLKSNAKGVILLSGDVHFAEINQVQCSEYRSIITEITSSGMTHSWGEANWFDAFIFQAANLILPWPFRPHHSSVYGHKNFGEIEFDWTASPLPTATVQILGEDGQTKLRHVVSSHYLESDANEGDPSRSCRAIQEVSMPVLFTRQILLLGCVGLLIGGLLAALLACVYSLVVLYKRSFAFMANLQHRLFDGYEKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK35</accession>
    <name>A0A8K1CK35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycoside hydrolase family 5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK35"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923:SF2">
        <property type="entry name" value="ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923">
        <property type="entry name" value="MAJOR EXTRACELLULAR ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="8">
        <location>
            <begin position="43"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="16000" checksum="E66DC149E28CAC1C" modified="2022-08-03" version="1">MDGEVGNPTEYPDMGCALPNYVSRNGKIYVIGPQGRTEALTIKGVNWFGMETSATLPLGLWSNPQTGTTAYAIAAFLARNNFNSVRLPICVESLVKNIAPNKDIVNQYENRAIQLNTHLNPLKGIIKALGHRQISVMISLHTLNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK70</accession>
    <name>A0A8K1CK70_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PLC-like phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009139</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK70"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051008">
        <property type="entry name" value="Telomere_Capping_Maintenance"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518:SF2">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518">
        <property type="entry name" value="MAINTENANCE OF TELOMOERE CAPPING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="66172" checksum="387CD67D25B1EE99" modified="2022-08-03" version="1">MSRKIKWKNAKMRRIVTKTTALAVLLAASTTIHLPSVYADDAPDQGLSNEPLTGDMFAIKPELWTSDARKSFHQWIRDTVPDTVPKDVQCKKVEKCDKHRVCVITCEPGSVVVDPWLQQALKFERKLAYRRNFCHAHLPGTHNSAITIADGYGVEDHVFEGYLKYLSWFKKGMEVHTNDQLFSLTDQLNMGVRFIELDVHWFNNDLHIAHCGGFHSALLDSLISAFNKIANWLGTDIQWDSQTIGCKPSLSSIPASEQRRLDDALKEISTWLHKPENKDEFLMIFFDDENNLFRWKKVTTMIKYLKSHFGPEEILLPADLVHTYGWPSFETLLASGKRVIFMSGSNYSPRGDDVLFVKDEICNWTEPQLPFEPYPSCNFPMEHMTPLDHRHWIFRPETSEIVYGFLNADGHLGDNTYILNETSIPPMVECGVNIPSPDNITPKRVESTIWTLTRPDVLEPGKCVALIRSKLTWVSLDCEHPGIVAGCVQHGHHTRWALGPQPVKEKDAAASCSSMSKFWVYDAPGNGLENKFLHALLMQAPTSVQGVWLDAAALASEAFDNRVANMSPLSRVEQISDELALNKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKE4</accession>
    <name>A0A8K1CKE4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKE4"/>
    <dbReference type="OrthoDB" id="68215at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="589" mass="66098" checksum="C46CC2E83ED3C7F1" modified="2022-08-03" version="1">MASAASPLAIADVRYLWSEVDRLKSQVQQLQQSERHAHDEQVRLAAYVGSFVTQAQLEAALCTKVSQSNVASTLDRLRSEILDVLEKKADLDVLQSLQSKKLDISVYEASTWDLKRFRTALEQSVHDLFATFAHQIEDQVRSKISIDDFDRIFNPEANGQKAAIENAATKIARINDQLERLQEYVTDDRQRQHKLADLNVSLLDLTRKHNASRNSIAQLFTTLETAKERIHDLETNSKRLDARSDALHSEVGVFETNVLKTTTEQQQRVTEMQQTVGRLEAMNNQVTETLGHIQQFTQNTLLKAMEAKFKHVNDRLESELGELQTQHQQFRSQSTHQANKTQERVLQTIEQNTVLESRIKRIEAATSTLREELASVRGPLMSAAMNLREENVAILEEIRRSQDESREIILDYKGLLEKTAESAYAPAFPLRPASSSSVFQGASARRKQNQFAVMMKRIGDGKLPQTDRPHTSDARLHNETRESGSRIRASTAGSTPKGKFISGRSNQADSGSADAICPLPQRPRSEAGSRPRNKSILYTMPTEAHASIDRDVGGIQDQGDYISEAMFTFPDPVVAETRATSLCSFPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKQ6</accession>
    <name>A0A8K1CKQ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007961</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the retinoblastoma protein (RB) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKQ6"/>
    <dbReference type="OrthoDB" id="844594at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000134">
        <property type="term" value="P:negative regulation of G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20548">
        <property type="entry name" value="CYCLIN_RB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002720">
        <property type="entry name" value="RB_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002719">
        <property type="entry name" value="RB_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015030">
        <property type="entry name" value="RB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028309">
        <property type="entry name" value="RB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024599">
        <property type="entry name" value="RB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13742:SF17">
        <property type="entry name" value="RE32990P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13742">
        <property type="entry name" value="RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11934">
        <property type="entry name" value="DUF3452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01858">
        <property type="entry name" value="RB_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01857">
        <property type="entry name" value="RB_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08934">
        <property type="entry name" value="Rb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01367">
        <property type="entry name" value="DUF3452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01368">
        <property type="entry name" value="RB_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01369">
        <property type="entry name" value="Rb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Retinoblastoma-associated protein N-terminal" evidence="9">
        <location>
            <begin position="119"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Retinoblastoma-associated protein A-box" evidence="10">
        <location>
            <begin position="518"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Retinoblastoma-associated protein C-terminal" evidence="11">
        <location>
            <begin position="994"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="409"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1067"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="473"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1076"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW65319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1105" mass="121395" checksum="5E3702F65F872DE7" modified="2022-08-03" version="1">MLLSPPRPPAGGRSSPIARFFTTATPSLWADISTNEPTLVRDAQQLYDQITTRQSPLRSTSLANDKKTASPKVWAVVAVVATRIARDLRRMNGARRRGNGVVGRKRKAPRGSDDESEPSSANDEAQDHDTDEMNDEGDDVAMPDANRWHVVDFLVEANVSLSVFLHHLSSLFDRLLLEPELLEVTTQLKEEFTVATVLFEKYRAMWKKFALHDPTSASRDVEAPERTESLFRMGWLLFVILKRRLAPRQGTGLGQLYYLLLAVLKLVISQVSRRSVEAEVAAALSALGAVKLQTTPSSPSVAAIDDQSLLEMLCASPKVDADEVTKSFGLVMDELMHMAREEGLLVLPSTAEIDDDEAVRRGVFRHQVARQNGSRLVDHYAVTYLTSCGCFDERVYLDEQSRQAMLGPRSALGHGDVETDSHGSTPTPPTGMPSRGDRAPSINPLASPVRPPGTPNRYDRSASSTPGPPPSPFTVQAWQWQGSSPPPSLSFTVPRGLGTPSTMQRFAGGLQSPFVAQTPVTAAVETSNWIRDTLTASQSFLTPQLKSFFKDCTNEPTDKIATTLQDLSHRLMTSRRRGAPTALALDTLYSRENGSPNTESEYSEVDGSLKKTKNLAIALFYRVLEALLVAERERLHTTNFSSLLNNETFVSSLFACSLEVVLKAHSLITLSFPFLLDTLGVNAFDFGKVIESFVKHGPKLPSALKRHMRDLEQMILDSLAWRSDSGLYAVLAGERQQAARESQSASSTPTNGSSTTSSTPRSTVLQLFFRKVLSLAASRIFRLGNMLELDAKYLNQAWTAIKECLSSQHQLLRDRHLDHVVLCSLYGVCKVNHVKPEVTFKRIIDCYKKLQTPQWGIHGSSAHGNNAAAHAAFASASISRNSHDIIREIKLDDHNTRGDIIKFYNRCFIPTMKVFLLQFQAQEKQLAAANAVVGGASASITTASTSDSEIVAEAAATVFEKVIQSYGPPRTPLRRPVRTAMSTPPLFGSPPRTVQLFTTAEVESLPVSVSQTSPKRVLTSNIYMSPLQNARLQNHRTHMTPRSHALYAFGESPSRDLALINRAVNNSRTAPAPPSLMTTDSATDDVTSGSNSGQNTPTTKRRRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLL6</accession>
    <name>A0A8K1CLL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLL6"/>
    <dbReference type="OrthoDB" id="168421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27454" checksum="DC96C2A119D06A98" modified="2022-08-03" version="1">MAAMVQSSALPLGSSHTIDLDWSISSHDLATNFLSNPVDTHTLEGSDLNVNIHLGYEDHCDDYEDASTATDSDSTSNSPLASPTKFLPLLQLFTKDNLDLAAAVGTSHTTRPQRRKRARMSAEERKIRHREVQRQFMKRKRARIAELRKIIAVVEKQHRLAIVMQECQQLQQDNERMRMQMNDRSEVKSSFDFDAMPFSVPVNSEQPSSPMGECDELMFDELPWDEILDAVSDEELASVDTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLN1</accession>
    <name>A0A8K1CLN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLN1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423062" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="23743" checksum="7145D823C9CD3E85" modified="2022-08-03" version="1">MFSSTLRICVLATMAIIGAVNATPSSVMILGSASSSSACVGIPISTRHLLVTSACVSANDPLVTASHLEETFRSHAVMNTSTFTSGDHALHLVTLQEPLAPSVKCCVMLPDIRQLDKCCVHPSQSATSSVLMNVDPSTGRVWYTDNVVVGDPSSCDHPVCVKSPSLDPVAAQYASFLLQHDQERQNTLLLGHGVTQEANAAGFHGFSWLPNMLASPEMQSYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMQ4</accession>
    <name>A0A8K1CMQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Ubiquitin-fold modifier-conjugating enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMQ4"/>
    <dbReference type="OrthoDB" id="10256182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061657">
        <property type="term" value="F:UFM1 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990592">
        <property type="term" value="P:protein K69-linked ufmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11686">
        <property type="entry name" value="UBCc_UFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000106">
        <property type="entry name" value="Ubiquitin-fold modifier-conjugating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014806">
        <property type="entry name" value="Ufc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12921">
        <property type="entry name" value="UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12921:SF0">
        <property type="entry name" value="UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08694">
        <property type="entry name" value="UFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008716">
        <property type="entry name" value="DUF1782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR008716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR008716-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="165" mass="18872" checksum="F88F46071DC68932" modified="2022-08-03" version="1">MDAPIDENTKRTVQKIPLLTTRAGPRDGEDWTKRLREEYLALIQYVKMNKEADNDWFTIESNKAGTRWTGKCWSFYNGLRYEFDLEFEIPATYPVSNPELCIPELEGKTSKMYRGGKICLTIHFAPLWQKNVPRFGIAHALALGLAPWLAAEVPDLVERGVITPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMZ1</accession>
    <name>A0A8K1CMZ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cleavage and polyadenylation specificity factor subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003829</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMZ1"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="8">
        <location>
            <begin position="251"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="9">
        <location>
            <begin position="482"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="599"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="610"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="745" mass="83352" checksum="86D7F4B938D438D5" modified="2022-08-03" version="1">MSKRKLAEDEGDERHIMRIMPLGAGNEVGRSCIILKFKGKTIMLDCGVHPGYSGHGSLPFFDGVEAEEIDLLLITHFHIDHVAALPHFTEKTNFKGRVFMTHPTKAVMQMMLRDFLRVSNISVDDQIYDDKDLHNCVSKVEIIDFHQEKTINGIKFTPYNAGHVLGACMYLIEIGGVKVLYTGDYSLENDRHLMAAELPACSPDVLIVESTYGVQVHQSVIEREGRFTGQVEAVVRRGGRCLIPVFALGRTQELLLILDEHWQAHPDLHDIPIYFASKLAAKALRVYQTYINMMNERIRKQIAISNPFQFEHISNLKSMDDFDDSGPSVVMASPGMLQSGVSRQLFERWCSDKRNACIIPGYVVEGTLAKKVLSEPTEIVALDGRILPMNCTVEYISFSAHADFVGTSGFVEKLVPPNIVLVHGEKNEMMRLKSALLKKFHDPKVYKPNIFTPANMQEIVLEFKGEKIAKAIGGLASEQPQQGKVISGLVVEHDSQTYLMDKEDLSTYTKLVSGSITQRQHVPFPDASFDVLLNFVRQMYEDVLYLDKQHRVIVCEQVVLTRQPPDRILLEWTSTPTADMIADSMIALAMHAQASPAGFKLSGHPTAACPHDHSKKPEEPHKGEPNVKTEDAEDVKTEPEVKSEVAEEPVGVETPGELERAAKELGESDQDALNLLIIFRLLKEQYGDVDLDFETNKIHIHTPSGIDAVVDHVSQQVECTDEAFKAKLVATVERIERALRPISTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNU3</accession>
    <name>A0A8K1CNU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNU3"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004517">
        <property type="entry name" value="PRK05862.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="30103" checksum="4C8E8132D1D20B93" modified="2022-08-03" version="1">MSMLFKATAKIQAPMARSFASKAADYEHILTEVRGKVGLITLNRPKALNALCDALIQEVNGAAHAFDADDNVGAIIITGSEKAFAAGADIKEMATREFVDAYKSNMFANWGDITKVSKPVIAAVNGYALGGGCELAMQCDMIIAGDKAKFGQPEITLGTIPGCGGTQRLIRAVGKSKAMEMILTGNMIDAQQAERDGLVARVVPADQLLDEALKTADKIASFSQPVVKMAKEAVNASYEQSLQEGLKFESRLFWSSFATKDQKEGMAAFVEKRKPNFTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNV8</accession>
    <name>A0A8K1CNV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNV8"/>
    <dbReference type="OrthoDB" id="530303at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="66887" checksum="69A3BFFFA4D65EF1" modified="2022-08-03" version="1">MADDSMLLATTTVLVYADARLQGLDHVLWSIDELVDVTPLYTPDRAAALGSLRLLKRVLKRVKIDETDPELVSNWCKKAMENAIKRKNLPIVECVHQFHPLPLGLSSLNLAIAVGSLELVQWMLLHRWDQLCLTEPPGVGDARRHTVDCCMQVPSVDATTASHIQICRWLYDQGYITSVGRLEDQAARTGDLDTIRWLYEQQVPRAMTELALNVAIDNGHVEVVQYLYEREEVRAMMPRYRYFELTEKAPPALATYLQNVVNANVVTPQSLYPLEIQEWCRAQWNTGDSAYVCLSRALADGEEDAALHLLNRREVMTNSPVVHDVVQHQDLRVLRWLVDRTGYQAIAQATVSAATQGNLSVLQWLHEHYPDSWVSAVMKAAVNHRRLDVVQWLCTNRSDGCSSEILMVAASNGNLRILEYLHKQWPYLLTPQVLNEAAQHGHLKVVKWIYAHMSSSPLNEAMALAINAGHLDIVIWLRQQQPDSSGSLAVDYPALEVARWLYGNGYEACLANIMDTVAGRGDLPLLEFLHSHNIDVITPDGISDVTATGHVRVLAWCYERYPDVVDLDQVYHQAKVYGKDQVIEWVTTLRGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNY9</accession>
    <name>A0A8K1CNY9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNY9"/>
    <dbReference type="OrthoDB" id="161647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="417" mass="46301" checksum="3C87842FF96A69BD" modified="2022-08-03" version="1">MLATMTIDETISAAETSKQATKALKCVAFTSKQVGDMLFRKHERVTRRIQSICEEIESLKTDVAENVTHQRERRQQLTEVEEDLEHAQLLGNATLVNELLDEVNVLKEEAKREEALYRAICRTIRSRKDTKRQFVREKSALDEELRNFNFKQKLIQTLLATCSRQSVSSNDTQGSSASQSDCGASEVDDSPESSSISSEEETKSEPISSPEVVYLRKSVSMGVNSPPIKRQLRVRSFSSDCVPSTKRESFETRPRHSLSVHFASPELTYMTDDAEVGEELRNELEVLDISSSLTSIAEVIADIPQAEDTTTENIETLESGVEVEVVTEVAEEQVIVKEEVSVVEEVVSESAPLCEDAVTPVEPEEAVEESPVVVESVVVEQDVVPAPEPKPVEKRGKLVEVKMPEDESDSDDNAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPS7</accession>
    <name>A0A8K1CPS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004256</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPS7"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF17">
        <property type="entry name" value="HOMEODOMAIN INTERACTING PROTEIN KINASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="175"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="745" mass="83787" checksum="835E87FF59234CCB" modified="2022-08-03" version="1">MRTRCLWSVVLSLDEDESLVILKSLSRDEDSGDVHAPLTWTLRCSRAFSCSPGAADCSSLSFESKLHRDESVRASVYETMSRPDETLGMQLSLRLQSTYAQCRGRPTESPMSALPVHCFATRPTNPVRSPSPRRVLTKKTEPQGNGGLDNEERNLIVRERDVLGGRRASPPQAEYIVLDLLGQGTFGQVFRCQNAVTKEIVAVKVIRNHPSYYKQAIVEVQITGMLNASYTAEEAPHMARLKGHFEYCNHLCLVFELLGINVYELIADNNFNGFSLDTTRGFLQQILHALVQLEDVGVIHCDLKPENILLAGSNALLSDIVYDRRYPSPFTLPSDHELEIPHLKVVDFGSACMENETVYSYIQSRFYRSPEVLLGIPYSGSIDLWSLGCIAVEMFLGLPLFPGVSEHDQLRLIEETLGILPQHLLRRGRHVLKFYNLRRDQTFVLKSPEEFAEENKSEVQISKKYFKHSKLYDMIHAYPLPKDASPVQIAHECERRDALLHFLGGVLRVDPDIRWTARDAVLHPFITGQRFDPSGGYVHRPMVAPLPRAPYQPLGSNHHHAEFHEYSGMVWGPPGIPPYGLHPPPIPESFGPPVKAYSKVLPLSERQQSYGRYDPYASSYEGANGPGSYYDSGLYVTPPASVPNHPRYPKVAPVQQPPSFPRLHIPVLPRLTSNETDGGYDANQYGNPPYQGTAPRVLTTKRLQEHGFQLSLSHAPAAKSQENRTSHTSQDAQPDVWVRKTQWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPT5</accession>
    <name>A0A8K1CPT5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPT5"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="24653" checksum="A43AC426F2B35F21" modified="2022-08-03" version="1">MSKTVLITGANRGIGLAFTAHYVKQGWKVIASARNLDAADELKALAPWKLLQVDTANEQSILDAAKAVEGEPIDLLINNAGLLTSLGLNEATKEDLIRQFEVNAVGPFLATRAFLPNLKLAVQAKGEAFVAQLTSRMGSIHDNTSGGYYGYRSSKTALNMISTSLAKDLAPEKIGVLLLHPGHVQTEMVGYTGNATPDESVVRVTKMIENATLEDSGKFQHCEGYVLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQR8</accession>
    <name>A0A8K1CQR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012043</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQR8"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="423"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="635" mass="70493" checksum="2D082DEA4EA69822" modified="2022-08-03" version="1">MDVAFEGQNAFVAAANGDFPLVVLLWGMALPKRVDLLVAEDLDGNTVLHHTASTAIDGNVAIVHFLLQQATAAGRPLTSLVEACNHAGETPLIRAAHAGNMAVVEALLQFGMAEINAKDKEGNTPAHHAAAQGHLWLLHYLLQAESRLNPSLAPTELGDTCKSKNTVLHYACAREHKVVVQYLLSQGFDPQQANVDGVSALDIAKYRKIEWLVKVLESNDRTFAEAPTKCRESRLWVTLLYGFILSGLFSLSYFLPWWIAAPLILLVLWLALKKIRKPHGHGGHSHGTKNVATLHPSKRDMVVTGSVVLAKPQKEPAFSKKHEPSGLSTLFKPQPEMIMGVWAAWVILFIFFHVVVWVDPVYKFVVTDWEPFLYTLVGIEAVFLLTWFRLATVCPSDPGVIRTFQVDITQMLANAATGVVPPEASYCRTCMIRKPIRSKHCAQCGVCVARMDHHCGWINRCVGYGNHRLFVCFLLLHIIVVVGFVLLAGVVFQHFLQPGNLDATLGSSVMRVWMQVPDLVADHLLALMVFLWGIGTVIGLSFMAVQHLGNMARNLTVNESINWRRYPYLKADPKNNSKAADKLPRLLNPFDKGGWHNTLEFWTRSGSSALDYRTVFRLPNAVDEPEEPIINVQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC4</accession>
    <name>A0A8K1CRC4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC4"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035427671" evidence="1">
        <location>
            <begin position="23"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="338" mass="37461" checksum="9E99F80F3B3D9C5D" modified="2022-08-03" version="1">MSGRRISVLLLVIAVICDITNAALSIPTAQDASGAHAESIKATASKISNGKRTHTTGGTSYAVYTGPSYSTNGSLTAQMQHEEQKKLANFRPSFIKRALNKVANSGIVLKNTKGLLDLYDILSSEFDKPMASDNSDLTFARQRVTYRSFALRPAVLKDLKGIHLDLYDSQLHEKCGCAMADMWRSTTFSRASPLTLTTRMQLGELLLHLIFTATVRNQMASGMATWHSLNLPYSPAALWEPMLNETLKYDEWVPPREYTAPSGLVASVIEYSASFYKQIPASESMLGVYKTAPFKDEPRLTRAIAELHERLAKIDAIITDGEQKEAWPFELLRPSRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRD2</accession>
    <name>A0A8K1CRD2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRD2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="414" mass="47622" checksum="543A3F241F83C07C" modified="2022-08-03" version="1">MSTDLGSDSETLAAIVAYIDAFESDSPEDLLSLTNSDSVDSLKHSVRRRFKERRVYSNRSRDHQRRELESLRLEAERLHARLAELKTARSGREQALRAHMDGRDDRRSEALQRRMVAVWKRVAARQKQMRQDAERENEKLRNRTERHQDVARTLKRFIEKQLTEEHHAASNLRLQISRSLSSSSADPDDLTRVFSGIVTDLQSLYNSNASWIRTAELSSMSADTSRDSHVTMLSPTCFVFELVNRQLFPFEFRVAANSYWDLSLTCECAMFDFFNETLDVDGRTTIFRAQMIEEPSIGRLRRFASMQKINETDRTVVTGIARSDSLQVGGHKLQEARLTEYYTFVFQPPEAEAQNESLMVASGRIVLDMGSNYLTSFEALSVLSAYYSTKMHEHFQWVAGNMEDQMLGLEVQCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG3</accession>
    <name>A0A8K1CRG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TKL protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04900">
        <property type="entry name" value="ACT_UUR-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="367"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="492"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="764" mass="84396" checksum="85C933A92EE8076C" modified="2022-08-03" version="1">MQSDRPVLRTSVSLTELTKHTASAGSLSTFIPSRPAAQGDLTPVASTTISSPSGVVLSSSFEGTSSAEEYLKDARKNSTDDLEVAPSPPCNTVSDTRLLYRKWRTGTSLSQSPDGHESIPENMSEIHVPDALSRSPYEQPGYLRSGELPTFKRSPEQGPSSFLRSPEQLPRIAEKTENVPLFANSYDPDLHARVLSEQIAAQEGVTGSPSLRPQGGSYGNSRTPESNSSSVMKKARSYQALEDLEKNGYFPAAPKPSALGVQRGLKDSVVNDMCRAVVKHMVGDVYVSSSGHHGVKKVLNHLYEPVLQSVQSHFKRLPARYALSVNPDDVPMHMRLLAKHQRNPDEININVQLQKDDDGNIVTNVCDVVVVSIDRDSLLDAITRALTSMKGSILDADVMTTHDGVTLDRFVVRGSFMADERQSELKRRIEENLARLSLGDHGDFKAPSRAAEIKPEATQTQVDANLAEQLGVLKMVDKNEIKDEWKLNITEIKIDTTVGSGRSGNTYSAWWRGTRVAAKVVDSSAQNAALSEDLLNEFHREVAVVSKLRHPNIVLFLGAAIAPPKYCLVFEFMQNGTLTDLIRSRKTPIDFFRIATEIAMGMNYLHLCSIMHRDLKSGNVLLDAHGTVKISDFGLSCVLDISGSHDLTAETGTYRWMAPEVIRHEPYSTKADVYSFGVVLWEMIAKDQPFRGLTPIQAAFAVARQQMRPALPRHTPIKIGELVEHCWHQDPNRRPDFSAILEALPLVKNSLKKRDFKNLGFTMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRL3</accession>
    <name>A0A8K1CRL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRL3"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051581">
        <property type="entry name" value="Ca-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524">
        <property type="entry name" value="CALCYPHOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524:SF6">
        <property type="entry name" value="CALCYPHOSINE LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="530"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="760"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="799"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="823"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="890"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116850" checksum="289F2C18F01F9990" modified="2022-08-03" version="1">MQKPSVRGFSLRGATFGTKVRVRKKKPHGSSVSVKRVDTAKEDVSNIAPIVTIDILIGDLRKKLHTIFCNADPTIAVTNLYENCSHQAFRYFTTTNTITPEAFHHRVNKLGLQASRELCLALFHLVDQEDLGELTYAAFARRIFLPAGYFNFSKPITPTADSPTANDDARETPRSARTLGDRPSSASSRDSSIRTPPIRHAVATSVSPNASSPSGNSTPRRSVLGDGHVALIYETMTLQEIEQCISRKLEERTSRTTDRFRQAFRFFTKSEGITFHDFHHQLELLQIHLSTEKCRDLFNRFDLDKNGTIELSEFTSALFQHEENEANLLRSASRLGSEVAGPPCRLEDFEVEAGSSLSIQQILSKLREKLEQHTSKETDRFRQAFKIFSKSTGITPPEFNTAMTKLGLKLTERQLQELFELFDFDHSGDLDLNEFVQGVMLDDASTKVWHTIKDRQKVEESRRKLYSMAVQSVQSGWTIAEIEQMLREKIEQRTSRSSDCFRQAFRIFKKVNGIKPEEFHAALESIGLTLDRSQADVLFERFDTDGSGEIDLDEFIHGVLPPDYTGHQWVAAADELHRQAAQKKKVEAMLRPDRFMTDVEMENWSLDEIEKRIRDKIQQSTSKSSDTFRQAYKIFKKSNHVTIDEFRERLLALGFRLTPAQCLGLFRRYDSNNSNDIDLQEFCLRILPPDYTGDGDHWSHSDKYHKKKESERLEYVKRSKNGLLTLPKFDEARVRYTRGQYIDRTFNDLRDDDVSLHIGDVNEKEEDAGMRPASPVTPRSGKPQRPETPRRPQPPTPQRPTSASSSQASTQTVSAPSTPKSPRAPEGERPMSPRTTRLEDRSPRIEIGPDARALRRATPPTSPRRVTTNAEAYSPMPHRPLSPRAMLSGSRSLSRVASPRSPRSPMVSPRDNEYIFEDDEILEDCDNASERLSVHSMRILRAKRFEAAMRRRRHGDNESVGADSTTSFSSTVQRAVGIAKYTPARSNVLLMQRFMRVAGGKGGGDRPHTARRIVDMAHRGKSKRQSHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRS6</accession>
    <name>A0A8K1CRS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRS6"/>
    <dbReference type="OrthoDB" id="71600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="31920" checksum="7682FE00C80BD71C" modified="2022-08-03" version="1">MRLTAAGGLLILVNLGFLIAGVLFVKFTYDLTGTGWIEALNESGYESQASKLVTIAQAIGFATCAVAIMGVAGAILGSRILLLVYSIVVVLALVIFGIIGGTGFSFRSKMTGWEAKEFPAEDMEKDFAPTFNEIYCYAQGAYFCNNATTADILEIFLPSVPAAAGALLPELQGINSLCKKQELASIVGSLDGVCKACGMAEKYARFDKILTWANDKCPRTATTSMWCAAFMQSDDLGPVYENSPYKECRDEFLDVVISWSSSLAFMGVGAAVAAALLLALSCFARRSGSSADDDDHYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSM3</accession>
    <name>A0A8K1CSM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSM3"/>
    <dbReference type="OrthoDB" id="181421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="212"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="42769" checksum="ECCD65D37AB3809D" modified="2022-08-03" version="1">MATAKSTYEWTYEASSFDPETTGMITAKAFAPDLVATALPNAQVQVEQLYKEQHAALGYPEAQAMTAAERSFAEEKTGCLSRLMFFFWSEEATEGSDIVGYCRAFQHSDNEIIVTTPLVKSGLGDAPRKAIEKAMFVSSKELSDALLQDLLTKREALSVVPFWRGLLNTSDYFKQLCDDDGFSASAADRLEMTRFMKDVGSTLDEAPDGIGICALDLEDKRLEQVFDVLKMAFGQPPLFEAWKRHYPQQPRFAADLTGKVAGEGHIMKVYETDSELRANGFEKQENSQLEFDPDYAERKAKIMETATTGFVCGVATLPSHRHKRLAKLTLQRSFFAAAQAGMEKIILGTDRQNVRAVRAYAHAGMVETKVENHGGITIKYAHVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSS1</accession>
    <name>A0A8K1CSS1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSS1"/>
    <dbReference type="OrthoDB" id="118280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="68601" checksum="2BB2597C3C363E31" modified="2022-08-03" version="1">MNVQTAALLRTTEATRSRSERFSLRAGDAPVPLPASRSERFSDSTRRRAAHRQSLTEDSIRPKLSPDVDRAAHLRRTSSYRTEREELSTYIAFSRRKSSVVDEEETGLSGFLEYRRLDGSWRPFLFQTIGYQLVIFRVHLTHQSTVMSTDIREATEISLVDEGDKSANKQADTRLFRLGINDTVITLRAVSHHAATYWVEGLQQLKAGDLPEVLTDRPTIESEDDIFRQIDQLTQVSPRYDQPESSPHLGFDCWYLTHAMLSIPHLQRRRQPSQRHPSAVDGQEERDGLVASSALVRRDATEEEELDGSDQDRLIATTTADALALLQEKEMQVRRRVRRRSKNCKNLAKFGSEHAVFRRVNTRHEQRMLEALHRVQQQICKLEERRLLMHSLELARFANVRQLATEKIRSYYQHFSHGYDPVKFGARAQVLADVVRSVLREDVESPAFPDIDTFLRQWSNYSRFHAEVVVSVTLIQPQETDDPDAVIVKCGGLTRFRISRDTIKHFFQPVIADEELVQQLIGKEYCFPFVTLFHFSTDGRVYRMEPRADLAAGLFQLMSDPFSTVKLLSASKLTSEGCLHAYPEPDPDERVVETETGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CST4</accession>
    <name>A0A8K1CST4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_006052</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CST4"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="12">
        <location>
            <begin position="482"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="141"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="279"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="584"/>
            <end position="586"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="634" mass="71693" checksum="ACD59F6F7F63B1AB" modified="2022-08-03" version="1">MDPATCAALHELQMEHLELLMDVQMDTKRISSVATLHMKRCGASPVTTLQLDVFHLTIHAVEVVIDGADDEHASSVFPIEWSVKSFTSFGEILAIQLPHELESAQTFRLVVRYETDPESPAVCWLEKEQTAGKTHPFMYTQGQEVLNRSFFPCQDSPSVRITYDATVTVPSELVCVMSAKQCGARPVVDSDGSTDSSRKQFVFEMKQSIPVYLVAMAVGDLVSAEVGPRSSVWTESCMLEASKNEFSGILDKYLTIGERLFGDYLWERYDVLVMPPSFPYGGMENPRLTFVSPCLITGDQSLCSIIAHEISHSWFGNLVTNASWSDFFLNEGFTMYAERRIIEKAHGRPLMNLTAKIGEALLRNEISALGESDPLTRLRVPLETGIDPGDCYNHCAYEKGYAFVCYLRHLVGSDDVFDRFLREYSLHFKFQSIAAEEMMAYFLSYFPDLADGSEVKGPVKFSTWLHEPGYPHFSPDFSDAKPMMDACESLAYYWRSADVPVQANVIYLSQEAKTWPVFQLLYFLDLLMEVSLSHTDVVIELGNALDLWNSTNSEVLYRWSHVLIKNEVNTKLDFVTRFMAMQGKQKFQIPVYRALVASSSPVIQQLAKDIYHATRPTLHVMVRDRIEALLKTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSX3</accession>
    <name>A0A8K1CSX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSX3"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49013" checksum="048A641BE361A912" modified="2022-08-03" version="1">MQSPLPRTPLMGRSKLRYDAATPKALDIEAARLNDVPAALQEQEERVACVLFALVGIGYLFPFSALTQPVDYWQMLFPDYNIEFAITSAFMYTNLAFLGVIVVFFGKPWYTGRIVGGFTGQLIILAFVPTSYFFLSSENANAIAVLGGTAAVAIATAFIDSSTIALVSQYPLRVQESFQLGVGLSTLIGSFYRDLTKLVFPSDQLVASTLIYFYTGALTIALCIFAYFKVMKLTITQKYVFEKLDAGVELTEKTRLLTSSRVSDDAFGVVTQPTKWTVLKKVIHLQLLITLVFVTSLSLWPPLVTEIKSFNFPSLDASGWWPLILLTIFSIADCAGRFLVRYRCGLTPQNIWIVVVGRIVLIPIFIAIVQRHFFTHDLWSLFFVSVLGYTNGYIGTLTIIFVNESVHPDEQQLAGPFTSFFLNLGLVLGASAGLLVEALVLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTK8</accession>
    <name>A0A8K1CTK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTK8"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051369">
        <property type="entry name" value="GST_Theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917:SF8">
        <property type="entry name" value="GH16740P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="87"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="26475" checksum="FBCCF5EA5912A202" modified="2022-08-03" version="1">MEQIYAFPVSQPARAVVWLCKLNNHAIEIKTVNMQKGETKTETFKKEVSPIGKIPVMKDGDFMLTESHAIMIYLAEKHGWEQWYPRDPKVRARIHEYMNWHHHNARLSSEVFFNVLMKNLGRSTPAVEASLKKKGRTVGAILKILEFWLEREGNEYLASKLHPTLADMSCYNEVVQLEVMGELVGLETKYPKFFAWLKRMKSLPHHDEELAGMMKFFHKFKLIPAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTV6</accession>
    <name>A0A8K1CTV6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTV6"/>
    <dbReference type="OrthoDB" id="120806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="16814" checksum="60A1E3F63F5CC6F4" modified="2022-08-03" version="1">MVKNLVSNGADVTTKTPDGETALHIAAARHGHTLISLLIKHGADVHVRDHAGYTPLTRCLRREVRYSSLEGTYFTAFELIKHGARSPDSFEIIHKHMEHEIITVGYLVEWWINELEEGKPLTRVPFNVLREGKANTETYLKELSAAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTW9</accession>
    <name>A0A8K1CTW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001676</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTW9"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="17"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="36823" checksum="D7D5F6F5B3A76034" modified="2022-08-03" version="1">MVLETRTVKALAAFKPGLTVEAWEYQAPALGPQDIEIAISHCGVCAADTHNLQNNWGMSQYPMVPGHEIVGSVTAVGSQVTDLQLGDRVGVGCATGTCLECSQCTQGKESYCAKAVYTYNGRRPDGSVTYGGYADSITVDSRFAFKIPEEIPSAAAAPLLCAGITVFTPLREHVKPGQRVGVVGIGGLGHLAIQFARALGAEPVAFSRSTAKEAEARKFGAVDFVDVTNPEAVAKAQRSVDVLIVTADAKKQPYNTYLSFVKFRGVFLLVACPVDDVSFNAFAMLMSNVTIVGSVTGGNQDMNDMFALAAAKNVRPMIQTLPMHEANKGLAMVDQGHARYRVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU78</accession>
    <name>A0A8K1CU78_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU78"/>
    <dbReference type="OrthoDB" id="10615892at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434365" evidence="2">
        <location>
            <begin position="18"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="39279" checksum="45503E0E98DCE9A1" modified="2022-08-03" version="1">MKPTMTLLTTAMAVTSAMDMSTPTPTLASAMSPLLVHSDLFYATATACDQLTTLPSSQELSEQLLPEDSFRGHMTVTTSAPKDGQHGCVLHVAVDGEIVVAPSSTVENVFDLTDSIDQKLAALAESQYLRGATHGLKDLTLQSVTVKINNRDYSIALQSTSAQNASSPSNLLTLNGGQCDPLAGHDLLNSILPKGAVVDDLHVLAGGDGASADCAVGFDVMASAPLFASNNEAFAFLKAVDDNLNALFEPSTAPTKPVTSLTSANLKFQTAKDENWLIAAPNELNLASSSMNMPTKEITLSILIGISVLSAMLFAIVYQKKRHEQRCQERHDLASKAAQIRRVSYRMGYDPLASHELEEKDEEKSGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUC9</accession>
    <name>A0A8K1CUC9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUC9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="743" mass="84127" checksum="F33FDD8E608FCB5B" modified="2022-08-03" version="1">MATQDPYKPMLKEEDAWRIALAWREPLQECVRLVSPYRIVPKNRIVPTYEWVAYHVLRHDGRQALLEQLHAFKAASTAWFALSCCRGYSGSEDPWFWKRVFGKLREPRLPSTKQSVPQFKFADELQHPVTDAVRFFDEDRGLVFPRIQLFDPHSIPEHIQDALLESFFLGQADLTPTMVATERELARYVDELTMYMVPSRTKRTIPVALSPFMFYNSQRMLVRLVNLPMEPIVTSIQPGSVCHPAYVVHALEYLDARKEDLASLEELRTFGQANPIEVSSVFLPTQQSTAVAPLFKIVFGMDPSVRVQVRHGHCEAFGPTCYHSEHTWSALPHARSFESLTLRFSDSFMSALKCAWIGYALFHPDSLTSSWSELELQVNTLLMEDVERVEAMAMGNNFIAVEEYRTPLSSAYFTADIRRESVIQVDPQPDGELLLITSEEQSVDLVPLDGEGGIELSGWVCVIVPAYGKGWTHASNILGFTVRTPSVASLKSLTIDSKKTSSAVLLRLLALIGSNLRYLDIGSMRPLDSEALSLVLQYCPSLESLRVRHDGSFWAEDKCDLLIGPQLKNLALFLPREKRPRSMGLFRFSMTGVQPAPASRPPRLSTFRVPSASATKTVLGDLQTLRLEAHALADFQQNRSAIQEMIHRLPRLESFHFHVEQAASKKPNARLCYSDERAFSWAMLGFPEQKPRPGETTLSFLSVVCHPNKRGCAVQRLDQDAVQLILQFALSCRLDVWIDQEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUU2</accession>
    <name>A0A8K1CUU2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUU2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053329">
        <property type="entry name" value="Merozoite_Surface_Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39110:SF5">
        <property type="entry name" value="GLYCINE-RICH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39110">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035458743" evidence="3">
        <location>
            <begin position="28"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1072" mass="89149" checksum="9548D90C831A65F2" modified="2022-08-03" version="1">MVQIKSMISLCLAAVALTTANLPSVQAEQTSLRGAGSLSGSVSGDISGGAAVGVGAGVGAGVGVGVDGAIQGSLKAESNVGVGAGASVGVGVGAGANVDGKVGIGGKVGAGVGIGAGVGVGANVDGKIGAGVGVDSKIGAGVGLGAGVGVGVGGKVGVDGKIGAGVGLGAGVGVGVGGKVGVDGKIGAGVGVDGKIGAGVGLGAGVGVDGKVGIGGKLGVGVGVGAGVGANVGIGAGANIGGKLGAGVGVGAGVGAGVGAGVGVGAGVGVGAGVGAGVGAGAGVGAGVGVGAGVGAGVGAGVGAGVGAGVGVGAGVGVGAGVGAGVGAGAGAGAGVGAGVGVGAGVGAGVGAGAGVGAGVGVGAGVGAGVGVGAGVGAGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGVGAGVGAGVGAGAGAGVGAGVGAGAGVGAGVGAGAVSVLVLVSVLVSVLVRCRCWCRCWCWCWCRCWCWCRCWCRCWCRCWCWCWCWCRCWCRCWCWCWCGAGVGAGAGVGVGAGVGAGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGVGAGVGAGVGVGAGVGVGAVSVLVSVLVLVLVLVLVLVLVSVLVSVLVSVLVLVLVLVLVLVLVSVRCWCRCWCRCWCWCWCWCWCRCGVGAGVGAGAGAGAGVGAGVGVGAGVGAGVGAGAGVGAGVGVGAGVGAGVGVGAGVGAGAGVGVGAGAGVGAGVGAGVGAGVGVGAGVGAGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGVGAGVGAGVGVGAGVGVGAGVGAGVGAGAGAGAGVGAGVGVGAGVGAGVGAGAGVGAGVGVGAGVGAGVGVGAGVGAGAGVGVGAGAGVGAGVGAGVGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGVGAGVGAGVGVGVGVDAGVGVGVDANVGAEVGAEAGAGADGNAGGNTGGEHDGEHDDEIKPPTTSPGNGDNNDGNDNGSQEPSAPEPTPEPAPTAPTDSDDSSDASHDTPIQGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAH4</accession>
    <name>A0A8K1FAH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAH4"/>
    <dbReference type="OrthoDB" id="1532798at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071513">
        <property type="term" value="C:phosphopantothenoylcysteine decarboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="9"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="20221" checksum="BC2B62C05F2C2A2A" modified="2022-08-03" version="1">MASSPRKPRVLVGVSGSVATVKVPELTVRLAEFAEVKIVVTKSADFFLQRAKEYHPSHWDKFEAIRESVPVLRDADEWICWDMVGDPVVHIELKDWADLIVVTPLSANTLAKLANGMSDNLLTSVCRAWMMSKPFLYAPAMNTDMWDHPMTARHLRILDELRYEMIEPVEKKLACGVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCE8</accession>
    <name>A0A8K1FCE8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010636</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCE8"/>
    <dbReference type="OrthoDB" id="68627at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40261:SF1">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="41"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="25937" checksum="C7D04246F0EE2F19" modified="2022-08-03" version="1">MRMLRPWHGVRRGFSAAASPTTRVLCSLEALKQREGNALKFALASASEEHDTTSKRRREALTGFVFYCEATQAPRAFVNQCPHALLELDLDDSDFFCEGFIQCKAHGAFFDPRTGICLQGPAATRRGSRTQQLGALPELSVTVQDGQVVLQEATITARRPRRTESDPETDELLEYRTQRQKELAKALASRVNDVQQIQEMLNRKAMERMQRFASSSSFVKKPRNNSTDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD09</accession>
    <name>A0A8K1FD09_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD09"/>
    <dbReference type="OrthoDB" id="118937at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="55320" checksum="7EA80DD3A8A8551E" modified="2022-08-03" version="1">MGLFDDVTTDPILKKPQSFNLLLPPLPAMIITLLLVTIPLKDPSLGWRANWTFFLREFIGSWCSSFSLELQSQSHVPELRYHLGKAALLNIAHAAFQIALMIALTFVAGVFPVPFTPMITMPLYAIFCWATRIYVARKELWSKTQPEKALAFRTKLWNFIDLMGFMVQIITVYAALATVFSRVPSRYQLLMVMTIQGFKILVRNIMWRKAQLNSQHDDVAAILVATSTQFFHSLFVSTCFQTSKSVVTLLLMVGWNILQDGLSIRSISRRTTRVERLRSKLNVSYNTTQDQLSLMVRATKHNSSAESNCLAIESSYLPYRALAIQIKAQASHTSDQAPAAAEVAWLHKQTELFHCREVLLLRLYMEIIAPIFYLVFVSTLQAIPNRTCMSYLGHVDLPLLSQRIFLQVITRVVLLLVLVHELKQASSSTTPSGLRQLLFITRYQGMPILVECVSVSLFVFGFSVQHNGNDISFRFAWLKTTNATSIAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDH4</accession>
    <name>A0A8K1FDH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004484</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Conjugated with ATG12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Preautophagosomal structure membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDH4"/>
    <dbReference type="OrthoDB" id="272162at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044233">
        <property type="term" value="C:mitochondria-associated endoplasmic reticulum membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.190">
        <property type="entry name" value="Autophagy protein Apg5, helix rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048940">
        <property type="entry name" value="ATG5_HBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042526">
        <property type="entry name" value="Atg5_HR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048939">
        <property type="entry name" value="ATG5_UblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048318">
        <property type="entry name" value="ATG5_UblB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20637">
        <property type="entry name" value="ATG5_HBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20638">
        <property type="entry name" value="ATG5_UblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04106">
        <property type="entry name" value="ATG5_UblB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 UblA" evidence="8">
        <location>
            <begin position="16"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 alpha-helical bundle region" evidence="7">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 UblB" evidence="6">
        <location>
            <begin position="204"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="32653" checksum="E8E51BF6C4D25876" modified="2022-08-03" version="1">MTLPTSETTTTLQQKLWYGQVPVVFSLYAPDVTTLHAPRPFYAMIPRMSYLVTQTRQVIEYFRDAAPPITGLPGNCIWFESQGRALKWHLPCGLLFDMSHPDGASAMLPWHIVVHFSGFPADELLPCENEQAVEMHFMHTLKQATFLRTGTTKVIMGMPEIQQTQIWTSILQNDFATYHTATRDLQLALPSGPSAPASNSVRLLPVRFHLTGEPVVQMPITPYDPDEPKRLRTLQDVVVTLLPDLFDVPAPSPPRVIAHGLSVPLDVPILALYQAFAYPDGYLHLFIPSVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE89</accession>
    <name>A0A8K1FE89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE89"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="68" mass="7849" checksum="844E947450B94971" modified="2022-08-03" version="1">MKLNATLFNIILMISITLFLFFMDLKDLYYKIAMCGPYPTFSFVLQTPEVVTDYDVTKAIKDANGTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFG4</accession>
    <name>A0A8K1FFG4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFG4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="35518" checksum="71E92F12AC5E9941" modified="2022-08-03" version="1">MNKSKWEKYATQSTLEEYKASCERACSFRAPCCHNENYTHLPVAFNATKRPERYIVPKELRLVPSLKAKLPDLRQQIKRFANHKIPSSSLVRYIQEEFGKKLNDEQQHLLVEHLLPRILDEERRATFMMAYLAKYTITKTRCCGRDVCYNCKRKLSWHYNEGCSSVKCWCGFYMTWPEEIRIRDKNARGLIPVDIFDLEVYRRWSKWQYNIDRALKGGLVSYVLATRLSRLDQELPPYKRVLQEMLQRYIWWRRFRKSLPEFKEQLMKGSLDQETKRQTRIALRRRGAVMMVLRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGL7</accession>
    <name>A0A8K1FGL7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGL7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="204" mass="22863" checksum="156A1A88FF225626" modified="2022-08-03" version="1">MTNRERARYYRQKDAAARAESVAAVKALHDQVGSLELQEHIHRQLLGNANTNANANADTDTHTDNDANTIAAPARANIVRLLIDFLNYRIDTIHSALHNTYHEFDGVQLTGDATAPIVRLDCSLRGRLLPSLVRQIYPHIIGNTVLLDRLMHEDMEYACRCWFYFSPDGMLDYHVVEMDGVGAINRVLENLQTVGRIIADIGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHH8</accession>
    <name>A0A8K1FHH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005358</name>
        <name evidence="9" type="ORF">Poli38472_005364</name>
        <name evidence="10" type="ORF">Poli38472_005373</name>
        <name evidence="11" type="ORF">Poli38472_005376</name>
        <name evidence="7" type="ORF">Poli38472_014894</name>
        <name evidence="12" type="ORF">Poli38472_014903</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000131">
        <property type="protein sequence ID" value="TMW57661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000023">
        <property type="protein sequence ID" value="TMW66555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHH8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40550" checksum="A029793F01D89B68" modified="2022-08-03" version="1">MRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIEMNCLDSEEEHDFQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVAKKLREEIATMIPELVEGKIKVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVILAYALARATHVWGPDATEYKPERWVDETTGKVRNESAFKFFSFNAGPRICLGMNLAMLELKLVLTSLLTRYQLDLVPGQTITYDNALTLAVKGELFANVNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW6</accession>
    <name>A0A8K1FHW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW6"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05269">
        <property type="entry name" value="TMR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="297" mass="31834" checksum="3A124B4F6459ED79" modified="2022-08-03" version="1">MPTSNTLLLVTGASGPFGKLVVHHLLTTFHVSPTRIVAGTRDPSKLQELADKGVQVRKIDFNDLNTVTKAATGVERALLVSTDEFLHRETAQIAAVEAFVKACVKHIAYTSLQGADKSIFAANHSHLATEEAIKASTGSYTLLRNGLYFENNLGWIAGALKTGQWFTAAKDGKASLLSRDDLARAAAFVLSSDSTENHVYELTGSEALTIDEIADQVSKSLKKPIEVVHVSVEELANTISETTGLPAFAGKLLATLDASTAAGLASDVTGDFEKLMGVMPRTHREWLEANKTFLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX1</accession>
    <name>A0A8K1FHX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHX1"/>
    <dbReference type="OrthoDB" id="105621at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05269">
        <property type="entry name" value="TMR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="301" mass="32624" checksum="CE5E61377AEB1C8F" modified="2022-08-03" version="1">MPATTSSTATLLVTGASGKLGKAVVQHLLDTVQVDPSRIVAGTRTPDKLSHFAERGVQVRHLDFNDAATVSTVALGVDRVLLICSDDVVGRLTTQKKAVEAFVEAGVQHILYTSLQALDKTLFKVGDDHRAMEEAIKESKVPGYTFLRNGLYYENNFGPIAGAKKQGKWMTAAKDGKLSAISRDDLARANAFALASDNYENQMYELTGPEALTIDEFVGHISELLKISIDVVQISEDELAQMISVMTGWPVEACKILSSLDVTIAAGRASDITDDYEKLTGVKAQTHREWLEASKAILEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FID5</accession>
    <name>A0A8K1FID5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FID5"/>
    <dbReference type="OrthoDB" id="97884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30738" checksum="8849ADD1B974DD45" modified="2022-08-03" version="1">MDRHVQGVVPLSPIGSSSEDGEAGQLVHPNREAGDQEDLKLTRKARRKEQCRVNQANYRKRKRAYEQQLAGYIKNLEDEINDLTARRETLSQLPLSEQSNQDEKSSPEEGIASFYQYLQDHRPTKAFSNGARIELSSALDLQWEEFASIEQLRHQWSLYVHQFDTFQVEMTSSDHFQAGDHVIVRITGSLFIRIANQESLNPADSEKWFYSVIRCPVQHRFEFDVYENKFTRITSEVDWVSGIATSTNTRPETVLEMLHELLQTSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIK8</accession>
    <name>A0A8K1FIK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000914</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIK8"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="16718" checksum="91C9B2CC784F7DCC" modified="2022-08-03" version="1">MARRLTKELGEFEKNSPEWCTVGSVDDDLMHWNAMVAGPENSPYSGGVFSLDLVFPNEYPFKAPKIRFLTKVYHPNVKTSSGEICADIINENWAPTMNVLYCLQAIKQILEQPDTDNPLEPEIAKQLQTDKDAYTQTAQEWTKQYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIV8</accession>
    <name>A0A8K1FIV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012883</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIV8"/>
    <dbReference type="OrthoDB" id="1903104at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15504">
        <property type="entry name" value="PHD_PRHA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045876">
        <property type="entry name" value="PRHA-like_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628:SF10">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628">
        <property type="entry name" value="POLYCOMB-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="164"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="260"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="440"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="261"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="506" mass="57291" checksum="2E903202636F3815" modified="2022-08-03" version="1">MPTNRRGGRKAKANQPVKDSNSSSSERPGTRQLPARERKPRVTYTPTVAPTRHYRRRQEVDKSTPDAQYRRLEARVRSQVKQLKYHETFLDAYEGEGWRRASREKLKPQKEIEVARSKILKGKRAIMDTLMALEEAQRSQEPQIPYLLELAKNSHREHDPENEQIYCSRCGSTNTTEDNDILLCDSEGCCRAYHQQCQLPVVATSDIPDGDEPWYCCACLARFNSLKTINYAFGTTCERVADVFPGLTNEEAMLGVATVAVEDDDEEDDEDFAVSGEEEEDDDDDDDDEVVDEEEEEGQGEDAEVTVAEENVSDEELQFLRTSDVIDQDRRSTRSQRHQATTSDDGLLGRQVQTEDGKRGVVVEQEESKTETIWRVVFYDGTMVLMAMSEVEDVVARAEKHDAESTEEGDGKEVDKSLIMKGKRKRKRVNYRALNDLLFAGKQDSDEEAEVSDGSPMAGVQGGEDEDDEDYTPATVTKENTGTPKRGRRTRQPVDYRSMHEGVLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIX1</accession>
    <name>A0A8K1FIX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIX1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="376" mass="41557" checksum="B9907711935C91DA" modified="2022-08-03" version="1">MTTASYKLFTPLALGEGLTLKNRVILSPLTRARCDPVTRKADDLTATYYAQRVGAGLIISEGCAMSEQGYGWYATPALYNREQMEAWKKVVDAVHSKDGKIFLQMVHWGRQGHSSFNSKNELVSPSGIPAINGRIRNAQGEHSPHEVPRALETDEIAGIVEDYRKSAALAKEAGFDGIEVHASGIALLNEFLQSVTNKRNDKYGGSFENRARFLFEVLEAVQTVWPADRIGVRVSPNHSYSDMGSEDNDEMFTYVMEELGKLKLSYLAILDGLATGYEDKYHGKCRVLTILDAKNAFKGPVFATASYTRDIAEGAIRSGAADAVGFGLLYIANPDLAERFENDWPLAPHAEYDVWYNPAKGAEGYTTFPPYKTSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJC3</accession>
    <name>A0A8K1FJC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000655</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJC3"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035458409" description="Obg-like ATPase 1" evidence="9">
        <location>
            <begin position="27"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="10">
        <location>
            <begin position="635"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="917"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="606"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="644"/>
            <end position="649"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110294" checksum="99AD88ACD9EEEEEB" modified="2022-08-03" version="1">MARWMTSLAVLASALCGTALLEGVEASNGAIIVRGNKMYNEKTGERFLMKGMTYEYAVSDKYYAKYSKETIATNLKGLKFNTLRVYNINPEESYKEFMTDMEKLGVYVLVAASPDNSEYFGKYRYAPIRKDLGPDGPVTGKGQTDNGETCYPSLLLEYGKKIAKNFAQYDNTLGIILANEIMQTDLTAGACVKQYAADLKNWMRANGKKMRMIPLAYAAADSAYNNPKVSKTVLQPEEYHVVKIQGLLCGDKMSDGFMTKSIDMYLINEYRWCEGVDYDATYKFFLELVKGLPIVVGFGEYGCHEPPTKARTWPMVPYLLQEPSKTKGFTNVFSGGLAYSYGEAKLDKGSAFPMFSGGSLDPLEEPSSKASTDYTNLKSQFDKYSPFKETAKWTDSTKCKWAPEVEESISSTNKRATKSGWIVDSCSSDVLKLADTDSWVAKSREGIVCNDDGSKCDVAITSALGTTQEDICGGDFVIEAGGGKCSTSSDCGSNGQCLTVNGEKQCICLSCYTGVDCSLKDTATCSKLSSSKDAPKIIFTAVGAFLVAMLVTFVAIGVVAQKKKKAMDKLGDQVKLRVPGAGPGSTQASFGAPTYPFVSHPVRLDRAKQPKDKMPPKKKEEAPPKVYLGRPSNNVKIGIVGLPNVGKSTFFNCMSKLNIPAENFPFCTIEPNEAVVPVPDQRFQWMVEKYKPASVVPPVMAITDIAGLVKGASEGAGLGNAFLSHIQAVDAIYHMVRGFDSAEVTHVEGNIDPVRDIQIIQGELRLKDLDRVKKLVDAQRKNVERGIGGKEKKMEFEALVRVKEWLEAGKDVSFGNWNPLEVDVLNTLQLLTAKPVVFLVNVSKKDYLRKGNKYLPKIAEFVKERGGDEPVIPLSCEFELELLDLEASGQLETYQKENPTHKSTLNRVLKMGYHALGLIHFFTAGKDEVRGWTIRKGRLAPQAAGVIHSDFERGFIKAEVQAFADLKEHGSEEAVKKAGKLKMQGKNYEVQDGDIIFFKFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJE2</accession>
    <name>A0A8K1FJE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJE2"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF147">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="116"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="300" mass="33462" checksum="C773A9BD7EEA43D9" modified="2022-08-03" version="1">MQRQPPPQWFLRDPAGIVIAGFCWCVMIVSICALWTSLSFWVGALSPVGFLDGTLLTASIGMCMWSHWQVMTTNPGVVPRHGASEKDDGDVFSEGEEEEMPLTEFENSEDDGSLLVFCDECNMYRPARAMHCETCEGCIVLMDHHCPWVNNCVGIGNHKFFLLFLFYVAVTSVHVLLLVVAEHLTCTRGKPFCGFQAEAFPGRLGVWLLAAACVFGLFCSGMLAMELYSIADDLIFTKIAEEVNVRTGCKSRSPLERHLSVLCGTNGFEWSWFLPTTQRRSRQEWEILGGIPHFGPGDQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKI1</accession>
    <name>A0A8K1FKI1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKI1"/>
    <dbReference type="OrthoDB" id="76256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="17157" checksum="FB3CF3849187A6D6" modified="2022-08-03" version="1">MTCTESLSPPSRVSTALIEFPTRDNVRRSVSCAEYGQADPILRGNDDDATVSQRAPRRFTIFYRDETLRENCDKNTRRMIESAKQTQQHTKESQTSTCGSTAVVLSNQQRLALKALKYRNLLDRMHAIDDDRLKDPSFDVLGCLGVQWCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKK4</accession>
    <name>A0A8K1FKK4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKK4"/>
    <dbReference type="OrthoDB" id="64449at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="384" mass="42739" checksum="31C5227E1604DB97" modified="2022-08-03" version="1">MSSDPANIFGGASSASQRAMWKRQVSQQRVGGEKSDDRVSKISLPNGEQIHDISKLYEKRCIKDEQRKAHRFMRGAQTARSFNEGRHAIDPAVTLTQRLNDVPDPYYNTDSGSKKSLQKRLEESPNPCLSAFSSSKDRFASTAAYRASTFASVVKEPYADPEAIGPGTYRSKRRSMEIKRKQVPLSSYVSKSSRFEEARNNVDAVLSSSPISRTGSSRAEFRHDKMKGSLISPTPRFKSDIFPEPYVSSKQHQLQHDAPDRFYDVSASCKFTIDSSVKSSNFRCSAMQSRASRLSSEASMVHNTPNHPILSSSTKETIGPGTYDSAPRSPVRPGTQEGMNFIMMPQNADRFGLPGPNSPFIEARFRRFPAEPHPPPSPPTKQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH2</accession>
    <name>A0A8K1FLH2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH2"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00538">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000066">
        <property type="entry name" value="Signal peptide peptidase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702:SF1">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471498" description="PA domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="77"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="235"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="410" mass="44430" checksum="91D6BC6C282C2A8D" modified="2022-08-03" version="1">MRVLGRLALLNCGLALLASSTEAVSSAVTTPPPESAWGRIYLQRGLAPIQYFRDRYGGPMLAHDVEFYFPRRSEDRSGCQPLPDDEQHVLQAANGTMVLVVDRGECTFEDKSRHAEAMGAGALVIVSEDESAKSPIAHVDPGEIQMPTVMIRKSAGDLLRSVTAREPKLTGRLVPIVCERKPYACIAQRPRDKEFIAVATGRSGVIVSETDQSTIGQFLAATFGGVLPSYPLHVTSLEGNGCAALEGAEVQGKAVVVSEGGECSALEKISNVQRAGADVALLSTTQGITHPVVAEAWLGYNITIVAASIDEDTTRRLREMTGKVSLRTKNDIATAWEEIHRLSMKSAWPARRDRREKMLKRLLATLSLDSSQLSALKHQFLTVAEGSNAAWDQLVPSEDTQSSETLHDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLR8</accession>
    <name>A0A8K1FLR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLR8"/>
    <dbReference type="OrthoDB" id="89305at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="74" mass="7912" checksum="3CB92EA05E34CB48" modified="2022-08-03" version="1">MSSNVIDTVMLYSDSLLGRVLSAFAPAVFKYEVDDLGPLVPEWGAADDHTPKQPQQEQKKALESVSSLPGAPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMH3</accession>
    <name>A0A8K1FMH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-decapping enzyme-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002599</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMH3"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09804">
        <property type="entry name" value="Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="308"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42476" checksum="B5330A6108FDA57D" modified="2022-08-03" version="1">MALQVDRAQSNAMNLQVLKRQDDAVMEIVDMASHVVVYEFDQSNQSWKRKEVEGCLFVVKRYSSPRFQIFVNNRLSTTNMTIPVNDSLEIDSVDTFLILRSPDASAQGGYAIYGLWFFPEEDRDKIHKLLQRIIQMAKLEPEAPAAIPPKPTKPAKQQGQPKQPKQKQQQQAQPQPQAQQQPPQAQPQPQPQQAQPAPRPQTPQTQQRSRNSRQRNKRSDSEPKNSKAPTAILQRPAKPDTAASSPSNGSTDSFVRNQVSTQEPVVQLHPAPVLAASASTPAASSSGYTPISREEGIAAGNAILGMLTQASSEPSQQPVSAKAHGPLLVPPTSTTTRSRTNSSASGAGQTSISKEQLKQTLIALLDEPQFFEQIYHAYVNRVHTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMU6</accession>
    <name>A0A8K1FMU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMU6"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422926" description="Glycine-rich protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="19278" checksum="4A39DEBDD926C984" modified="2022-08-03" version="1">MKYSIALAASLAALVSTIEPISANSVAISSDAKLPSPTEALDTVKNIDLPKGITLSGTVEPIQAPASIKDAGTDAKNKKESDITDNQIAIANDKQDHQDHQEWYGRGLGWGVGGWGGLGWGGWGRWGGWGGFGPYRFGYSCGGLGGWAYPLGYWNAFGAGLYGGGCGLGLAWGVSTTVRRMLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN47</accession>
    <name>A0A8K1FN47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN47"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467011" description="DJ-1/PfpI domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="10"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="253"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="553" mass="59192" checksum="A8302E9800DDC09E" modified="2022-08-03" version="1">MVLDRALVVGILLFQNVTTVDYMGPATYLEQLGSAVGQKLEFHTVSETAGGPIQPIHWGPILASNSFEDAPRKWDIFIIPGGTGTVQISKDPKYVEYARAAAENSTDVLTVCTGARILANSGILDGKKATTNKLKFNEIAAESPEVDWQAQARWVVDGKYWSSSGIMAGIDLGHAYVSEKYGVDVAKKIASEIEYVPNTDPANDPFTYITKETPSPSPVPSAPASSRPAQLPFRIGVVLYENTTAMDMSAALTFLEPLKTLAGKKTEMYTIAEKAGGPIQPANQVPLFASVSIDDAPRKWDILVIPGGPGDEAFIKNIKMLEYVRKAATKAKDVLTVSTGSRILAATGLLDGKYATAKKTEILKIQAAYPAVKWIVNRRWVDDTKYWTASGSTAGLDMGFAYVTRRYNLKAAEKIATNTEYVPITNPVRDPFGLPTPAPSVVPAPKPPPKPREPPSSSAVPPPNPPPVPQQTPSSSTVPPPKPPPKPRETPAPPLATPAPSTTQTPGAGPAPAAKGDYVYAGPARPDSDSLNTWCSVNCPQFCPTQFCKKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNI5</accession>
    <name>A0A8K1FNI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNI5"/>
    <dbReference type="OrthoDB" id="160432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024135">
        <property type="entry name" value="LAMTOR5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16672">
        <property type="entry name" value="LAMTOR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9362" checksum="948B0A9F14072AA0" modified="2022-08-03" version="1">MAEGMQGVLVNDAQGLCVKADGDLKSASEVAGFFTSIVESATNLGEGEEGEVPTVRIETSLRTLLVSRVMSDNGERTIVVSKASEEASGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPS1</accession>
    <name>A0A8K1FPS1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPS1"/>
    <dbReference type="OrthoDB" id="166809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451952" evidence="2">
        <location>
            <begin position="22"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="40898" checksum="4973FB5A09242D17" modified="2022-08-03" version="1">MRMRATALVAALTLLSAGSEAARKVEIRVVPRPVVVPETAAAKEPVPYREPMDPFGPFSSSYGLACLKDNKVEMDDKPAFLDFCHLKNITIIEEVVKAPEGAEIGVTGLQVASTDSSQTGSEGNEEADAGSEEATETKSEEEPTEVEPPAPPMRKILGIYKGWHIDPIHKNYKHMIFDDGDECTTYGKRNSITAELVPLSDSAAPSRIFGFRKIDECTYFVKVEAYVPDYMQTATQGIHSSGVIDISDPEETINEICSEKKCMYSVIKDKVEAVRQDVETVKQSLEELFSSDSSAVTKMTLDSASAIIKSTTGIMERAIEMLEATENLQHTIKELQVGVPSDPEPKQAEEPDASAKTEEEAAPEVKEVTESVATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPT9</accession>
    <name>A0A8K1FPT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPT9"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF511">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="102" mass="11471" checksum="1C912DA5488C4E0D" modified="2022-08-03" version="1">MATDEPAHVIDHVFLGSRAHAKDRELLEKLQITHILNVTPPKKVDPSAGVPNFFEKDKKFVYRRCPIYDNRAEDIFGVLAGSIAFMEQAKFYVATSTCSVCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQR3</accession>
    <name>A0A8K1FQR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQR3"/>
    <dbReference type="OrthoDB" id="291792at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031926">
        <property type="entry name" value="TMEM135_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15982">
        <property type="entry name" value="TMEM135_C_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Transmembrane protein 135 N-terminal" evidence="3">
        <location>
            <begin position="331"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="537" mass="60696" checksum="06585CFE45880F5A" modified="2022-08-03" version="1">MNTLTPSPSDLSIFSHNDEELDDEDDDSEDDSEDDASPSSSNSNSTGDEPATERASRGLVVLTPGDEEQQLSRELLDALYLGTSNFLLAYNTRAGIGVLLRIFKLLQKRQFGAIVDPQQLLDEKHLSFRVEAVSMGLFLGWFTGGYRGLKALFPRLIKRLAHQKDEHSDANQKSQQSRLTPEAIEEISTLLAGACSASALFFVNAKRRRSLALYALARALQCGYNTAKRRKYWHFWGSQWRYGDALLFALSSAQVMYAFIMRPSSLPGDYFRFIQKTGPVEREVLEMVRLCNRGLPLDPEMVQSFITKHRMTRDFVVPVGCPDQVSCRFVHHQASTCTMGVIQTFRKAFGSAFPLYLSLFIVPSVVIHFKKFLARPFSTLGRSVLNATRSNAFVSSFVAIYMGLICVQRRVMPKDHRFTYYLAGLGASGAIFIEPKSRRSELALYVLPRALDSLFIILRDRRILTGVRHGEVLLFSLSMACMMYSYEHEKDSMGSFLHSTLKRFLQTATDKKKIFLANLEHQQQRSADHKEASRLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Y4</accession>
    <name>A0A8K1C1Y4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Y4"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="459"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="79445" checksum="A9A2056A0A17472C" modified="2022-08-03" version="1">MRSVPSEPTEPIFHRLLAASLMSFSPTRSIRNMRTATRVLALAFTASLGLHAASAAECTSLKQNVLTSVGCPAQCVDKNAPCVLYASQDTPKCVPMGSSGPCLKDAFKLSDASEECDVTYQCLDTLVDNKIHKWFLTLETTTSANKVATAFVTQVANIEYPDDVLTIQLTGGVATTPKGTVKNVLLDSSFFQTPPSVTSFFVTDVNLQKVIEDTKTVPSTWQAVAFNNANLNKVPTVLSNLTLRYVEFTMNYFTSFPEMSDPVMKAFESVTTLKLQYNELTDFTTKLPAVETLNLTGNPLGKVPDVIFELKTLKKLSMRQCNLSNIQLDDAQYTFLDQLDMDVDISVTDCGDGFAPRNLSSGAGQVCMPSTESSGGGNGVAIGVGVGAAVLVVCIAAFLGYRRRKNKEIGGITRTGKSGTATDDTDNLTIPFDPDSEYGSSSIWSDPDLLAVRVDFRDVEPIKLLSRGGFGEVWLGLYMNENVAIKRLLSDKKTMTDALAFAQEIKVMARLDHPKIVRFIGVAWSNATSIQAITEFMDCGDLRSLLDSSRASSLTWANLKCQIAIDIADALVYLHTLNPKLIHRDLKSRNVLIDAHTGAKLSDFGISRDRASDDRTMTAGVGTARWIAPEVILSGHYTEFADIYSFGVVLSELDSCKTPFHDATNTNGAKMPDVTILQLVSAGKLQPSFTDSCPEPIVRLARACLSFDPAQRPSAIHVSYELRKILKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C282</accession>
    <name>A0A8K1C282_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C282"/>
    <dbReference type="OrthoDB" id="129725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="319" mass="34813" checksum="C08637016EE57F5E" modified="2022-08-03" version="1">MAGRGRGRASTLPAWMTKQADGQGNGPAPPAPVAVSVPPPGRPEQFEDAPERARPAYHDGYTNGYNAPPRMDRGPPPPPPRDAYTESRSQPYYGDLNGGGGPPAGGNRGMMAHNSRPRSRSRDRGGFDDRRDDRRDWDRRVPPPRARSRSRSRERRGGWDGYGGGRGGHGGAYGYPGDRRSRSRSRDRRPPPYDDRRGGGGYSRNGGGYDRPRDGGRYEDRGYGGGSSYREDRGRGDDRYSRGGGGGGYNDGGYGREEPVEQPDGDAAARKTGFMSGRRFNDFVKEAAKSAAEEFRGNDAADGGDHDDRTRRDYSAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2F8</accession>
    <name>A0A8K1C2F8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sugar transporter SWEET1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_013109</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2F8"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000007">
        <property type="entry name" value="Bidirectional sugar transporter SWEET7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000004">
        <property type="entry name" value="Sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF30">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW55218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="246" mass="27188" checksum="59FA8603BFF700E3" modified="2022-08-03" version="1">MSATQPPPVVPDVVVQTIKASASIAGCYLFASLYPEIRQVRINRATGTMLLLPLLSMFGNCVLWTLYGFLIQAYFPMVATNVVGLGFSSFYMAVYYQFTPDRRRVRRQLLATFLALFVVSMYPVFSYEPRKVVQQHIGYLAITVCAVMFGSPLVVVKQVIVTKKTDLLPFGMIVAGFINSSLWLTYGLCIQDAIVTLPNLLNLCLGAVQLVLFCVFPRGKGYDKVTATTSPDNDVVEVKVSNGNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2I8</accession>
    <name>A0A8K1C2I8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2I8"/>
    <dbReference type="OrthoDB" id="417983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="22407" checksum="23E454DAF2355C18" modified="2022-08-03" version="1">MAPLMVQSEGVARNPEIAHVPVPESVFLREEGLMQPVQRRERLAFETKYHHARRALEQAERDERRLHQIIKGRHATNDILNSDALGSDAGSNRARGEPYKPGLLSHDMALKPGLPREYQRKDDYAAPRHNTHDRIFNETPMPWGPERAQHLRNEGQAGRPFDIVNGGVVSYFPPTINEKQHSWQGHPSVIVHPYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Y9</accession>
    <name>A0A8K1C2Y9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Y9"/>
    <dbReference type="OrthoDB" id="90846at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="156" mass="17218" checksum="6071BA01ECB9E7B6" modified="2022-08-03" version="1">MLPMMIPLRIRNQNNQDTLYAQQRYSPCRYTTLSPRGDAAEDDDGGRGPGSLALDELNTMAGNTERKRCSLYSSDRDVTPTVLPAVDTIYHSEKLHALTNLVEKQGNMAITLQSPTPRFETPSSPSPHPGAYSPERFVGAFPILLDKVTPQSESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C363</accession>
    <name>A0A8K1C363_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010523</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C363"/>
    <dbReference type="OrthoDB" id="10051896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035450125" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="19"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="51"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="28967" checksum="6FB47D42EB998161" modified="2022-08-03" version="1">MKVAAIIATSALVVVAAADDKPLSYTKYLTSVQMQAQLLKAENTSAIKPLIVGGTEVPVGQKLWTAGLRETATGSDFCGGTLITPKHVLTAAHCQGYTKYIAVGTHYLSGKKDGENIAITQEIIHPSNNADTMAYDFMILELSKESTVTPIKLKTAEPAVGVTATVNGWGVTTEDGSQPSGMRQVDVPIVSDSACAKVLDIIPANNICAGGKKGKDSCQGDSGGPLTVKSGSDDVLVGVVSWGNGCGLAGYPGVYAQVSAAKSWIDSTVKKAGYTATWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3U2</accession>
    <name>A0A8K1C3U2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase II subunit beta</fullName>
            <shortName evidence="2">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3U2"/>
    <dbReference type="OrthoDB" id="3971593at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000008">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="27552" checksum="263E34FD4ADA5CD5" modified="2022-08-03" version="1">MSDYEEEDEKWIQWFCSLSGNEYFCEVPTSYIEDSFNLYGLRALIPNFQEAMNIILDMTDIPYDDDVPACAAELYGMIHARYIITSHGLDSMMKKYRDRDFGVCPRALCEGQPVVPAGMHDEWKKSEMKVFCPKCRDLYTPVTEYNSPPIDGAYFGTTFPHLFFMTYRELEPPPSTVIYVPRIFGYKIHNRGANRRRLALTALDEEDAQRRTSACGRRKGEEDVDTSAVKTKKRKQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Z4</accession>
    <name>A0A8K1C3Z4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Z4"/>
    <dbReference type="OrthoDB" id="113601at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="68952" checksum="0031BF346429A45A" modified="2022-08-03" version="1">MPSDFPVPRTELPKVHVSRQEYLARKLQMEHMVEQMVQEYEEYSETNLRFIDPRRWRQVATRERMKLYKERWSFVNGTTPSVNSTSTTSSANEDEGSRWMHRMISTSETAENLKFMLLVGERPGRVEDAMHAVVAANQEELALVVIYLHEEVADCAILNTMESPTQEEPFRYLGYKWFVKPSPGASRLVKNRDSLYVEYSGMTKTTGGAVLGYHLMHSIDIPNFPDFRDRNCVRISQSIRTLYYQKEPDVVEVFMMGNVDISGLIVSPIASVFAYDALFGMPRSVDCGEAKRLTELIRTRRLDRASRGRNLQQNLAPICSLCHHEKKMFSKTKLMACELCERTVCHRCCVAKRIFKSSGILGHYEKANCCKACLHDIRQAAQRGHNKSGRPRERSQSSRKKTSESEKPRQRCRSYLGSAQVTANINEKPGISITSTVLTEVRSSVGSYEEVEQDRASVASYGRSRRSSLIQELHDGDAVLRSSCISEESDVISIAPSVLGDSSIMPMPQQESDLIPLTLIEYPTQVSRGNCRGPHQHVQQPATYRSRRHSVPPVEEDFFARMQRLNQMAEATYHTIQVNETKMIQMQKCQFSSDRGDQRRVVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4B1</accession>
    <name>A0A8K1C4B1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4B1"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="425"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="659" mass="75364" checksum="74BECB3F3125C8EF" modified="2022-08-03" version="1">MNAFFWSRKKPSKELVLQVDALLSQLFPEEKLDAALAFKLLLDRENVHDFRSTVMSTDMSIDSLDEALASCVIAEYGDDGREETDGVIGSVIGAVPEEENSDQSGEDDLRPVEVTIPEELERHWTKIRSIFQAWDDEPTEREKKMNRMAELLLRYRVLEKMLIPKVLTAMTFETRKYVSHVFRAMTVHDFQGFIEYVGDRPEIMKWLVEGYKNNNTALICGSMLRDCFEHESLTLLFLNELHHEFEVLFKVTKTNTNFDISADAFRNITKLLMGHKAVTVTCLDVSFDRIFGLLNSLLSACNYVTKRQALQLLAELLLDPVNFSVMQRYIASRENLKLVMMLLRETSQALRMDAFHVFKIFVANPNKSPEVAQLLVRNRDKLLTFIREFGKTESNREFQQEKSLLVFTLQRLVEPLPQPLKTAASLPSMQSSSTSSTTSSLSSFTSTGTSPPSPSSLSMRKSISEIKPKRRVRERNTVRATADTMVTTAWGKYQTALATHPIRTKAITSAFVGMFGEILGHVLKHKTLKGLSPRQVLAFFAFGGFVTGPVLHYWYMFLENQTFTKQKLTPNKKLLLDRLVYTPPFTALTLFSLGVMRGSSPKASMETVKRIYWGALLMNWRVWTVTQWLSFHYVPPQFRVLWGNCVALWWNAYLSLAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4R7</accession>
    <name>A0A8K1C4R7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4R7"/>
    <dbReference type="OrthoDB" id="116263at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="301" mass="35342" checksum="DBF9695F01F32C8E" modified="2022-08-03" version="1">MLPPLERRRADLSCVAACAFDDGSALFPVASGSTRMAVVLLVWIHNNMTSIPELTASLIVHKQAELTRQYSRLRSYSFSATVADRFFSDNSLDRQKRVVDCTKRRQARAQEKARLQSEQLHQLQEQYERKAQERVRRDARESLRLTRKLEHVAAAYIHEAFAHYEELAMTMRHDSITVIPADEERQQTQQALAHAVLVGKQMTSMEALLLKQVDELEARLKEATKRQNDENERLRRLRRWLELRHSKEDDHLRAQLEEWEARKRHEIRMEVERAVEIERRARLRDKQTPLKRMTDGALISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4V4</accession>
    <name>A0A8K1C4V4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Drug/Metabolite Transporter (DMT) Superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006480</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRT-like transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4V4"/>
    <dbReference type="OrthoDB" id="416555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013936">
        <property type="entry name" value="CRT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326:SF1">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08627">
        <property type="entry name" value="CRT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="44496" checksum="E7BEB1130668E728" modified="2022-08-03" version="1">MGLHTPFVSLGIDAWTGKPYHLCSKKSLLSFGIVILLILAMASERLMFKAMVDRMQSYRYFLCQLMTFLYIPPLFCIVGYKSTQDEFIEEEVTEFPKYHFFVMGILDLLYAMMLFIAGGNTEPMQTLLLMQASIPLTACLSAVFYRTSYSRVQLLGNFVMAAGLVVAFLPSLNDFNSDNFEDREVAWNTLVYLLAAVPGALSMLYKERAIRDQPMDMIYLNAWVTVYQFIVGLMVAPVVFDADVLHLEQKMSGLECLINGKNEVETDHCELGIAILLIFIFSNVLINFLLLQVLRLTSVSVMNVTTILGFVASFVVLAWYELDPDDFGVRILRNWFSSTTLVLDFIAFVAIVVGKILYQWEPDPDTEATTRSAEDKEAQSLLNELDYGYRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C613</accession>
    <name>A0A8K1C613_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Intraflagellar transport protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003003</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFT56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C613"/>
    <dbReference type="OrthoDB" id="95390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120170">
        <property type="term" value="F:intraciliary transport particle B binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035720">
        <property type="term" value="P:intraciliary anterograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000372">
        <property type="entry name" value="Tetratricopeptide repeat domain 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:001373">
        <property type="entry name" value="Tetratricopeptide repeat domain 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030511">
        <property type="entry name" value="TTC26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14781">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14781:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="64015" checksum="38F13D13817B5391" modified="2022-08-03" version="1">MYVAKPKQTQRVKQQQEVARAKTKKGLTVEECATKRDFTGAVAILEFNLKSDEGSRGDEKKKTLMWLAYAYFHLGNYQRALDCYEQIRDPDETPEIYLFRACCMYYLQSYKDAMKEAVKGPVGALQNRVLFHCAHKLGDEDKLLVYHQQLTDSKEDQLSLAAIHYLRNHFQEATDIYKRLLLENRDDIALNVYVAMCYYKLDYYDVSLEIMQAYLQAFPDSVVAVNVKACNQFKLYNGSAAKDEIKALTDRGFNVETNDLVGHNMVVFEDGQHALRVLPPLVDSLSEARLNLVIYYLKHDKLQEAYDLIKDVEPSTPQEYILKGVVHATLGQATSSRQHIKTAQQYFQLVGSSPTECDTIPGRQCMASCFYLLKQFEDVNIYLNSIKQYLYNEDDFNWNYGVSLCNAGSHQEALETLLRVQREDYRRDYCYVSWLCRCYILNHNPSAAWDLYLKLDNSDDSFNLLQLIAHDCYKMGEFLYAAKAFDVLERLDPDPEYWEGKRGACVGVFQRMVAGKASRVELEEVLSMLKANNNPQVEYIVRIIKKWCAENGIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6P7</accession>
    <name>A0A8K1C6P7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6P7"/>
    <dbReference type="OrthoDB" id="427071at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039210">
        <property type="entry name" value="OGFOD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650">
        <property type="entry name" value="PROLYL HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="198"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36652" checksum="2AB6D2D517888C26" modified="2022-08-03" version="1">MAKQGGRSRSAKAPNKPTTTKQTKSSSWSTTQSLLLAAVVVVIAVGVSQYGSSHANVSSDLYIPRSLPVNHKRFDIVCHMKKKSPAFIPGCHKVGKQCGRALRDQFVTPEEVVQLREIAEVGMANRSCLGGPTIMDINTGFVKDGDGLVNIYQSHPKAAPIPRFTAEQFDLYRRTIEKIRLALIEEFQLEHLYFTAPTFITRIVGNASWEPTEIHDEYWHPHVDKDNTRHYDYSGLLYLSDYGLDFTGGLFAFIDKKSEQVVEPARGRLMMFTSSKENLHQVRRVETGTRYVMSMWFTCDERRRFKNFLDGKMHVHFKRTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7D9</accession>
    <name>A0A8K1C7D9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7D9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="190" mass="21004" checksum="91494D102158D72C" modified="2022-08-03" version="1">MVFEAQTLIAAEDTSTVENRTRGPDLEIQRSVEYKRQQNAVADRLRRKLERQREAERAASQTGAPKLTRDLPSSAQAKPASEVTETQATKSKKKKNKKKKNKTQQGNIGQLTEDDVSGQNSVGKSTDTLQQFLSGNGMAVKKEEEEDDPVDELADALTALKMQDSAIEDARLTEVIKIIDGLGSRVKLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7K9</accession>
    <name>A0A8K1C7K9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013362</name>
        <name evidence="3" type="ORF">Poli38472_013364</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7K9"/>
    <dbReference type="OrthoDB" id="101217at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087:SF161">
        <property type="entry name" value="TUBBY C 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="215" mass="24211" checksum="8182DA5EB4FD811D" modified="2022-08-03" version="1">MGNAASDTHRELLSAPLTEPHIPIAAVNPRFCLSTPVLLHLKEKTWSMSGDDFVIRDVQTGENYFRVDGSVFSMTDRKTLIDASNNAVAHMRKDPFSWGITINDIYADADAQEFLFQIKSKFSLFTSVLNLTFRNLITNKQCRMGLEGDWRARNAVIWLDVGNGQLIVVARVRRPSSTARNIIFGKQDYYVEIPPNVDVALIVLICVAIDESYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7X6</accession>
    <name>A0A8K1C7X6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">INTS8 TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Integrator subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7X6"/>
    <dbReference type="OrthoDB" id="64340at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038751">
        <property type="entry name" value="INTS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057980">
        <property type="entry name" value="TPR_INTS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13350">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13350:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25756">
        <property type="entry name" value="TPR_INTS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="INTS8 TPR repeats" evidence="7">
        <location>
            <begin position="750"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="928" mass="102669" checksum="9F7D5B489A5FF44F" modified="2022-08-03" version="1">MVVMPGSPRPNAEDDGVYRSIFQQPQLEIPPRAPSYAWFEFLLHPDALQRHLTTLRQQQADGTHSATSAIELVREFLDQAQLVADEGNGRNNRYSALLRLAAQVALQMKIPLDAIEQELPLHFQRLLLDGIVDFAESEQAGGRSEFTQDVAAFTPRLAQLLHHRWTLRTLVKESQNGYLTATNKNDAEEQVSGFQVALHELVLNHLNVANSVQSVLMEDNLVDTLPLQMQFDAFYDLAIYFFSFAAYEKAYECFSRAFELVEDQAGADPSQFQVSAASKASLEGYLAACEAVLASSSTGANETNASSPSLSTQIDDALAAHDLAHVVELLETDVIADATTKCPPGYRQSVELQVLRMLRQTPSHQLRDSYKRVALSNALDSVYHSTTSAQHEPSSSVSASYELQTALCVVSRLLQEEAMVQARHPDEDAAALFMPLVLFTLRLTAHLEQNAPSAAVRDRLQSFVTGLVHYFPCIPRIDGASSLLQRIGIRPPETDANALDMMIANESTLRLGAKRQRSHYRAATDLNGLYVFSRGSGDKDALLQALQEEGERIVFPSSVPQARSLAAFLTLHSSWDVLEQWKSRLDASAPVAATVDLALASGALMQYVATSITVSESNDAHVKIEFVVTRCNHLLHEVLRCRRAEAETTGDEDEDGWLVMLPLWLLETLVSVSAGLLHRASTRNLSDHRVSFDLTPYGDVALLVAFAPETTGPSEDVSDEALATTQLIKSSLREIVALHAKGIASLVRRCPREPRWHSARADLALFPLTKAKQPSPSDPRAALCDYLAAASLATNYFSDSVSAIDIIDQNSLVRMSQCLVKVGAHVAAAVLYQCFGAEEFKYGLRILQLAPETHDAAFFQFFWELPFLELLVHLHASAKHHNPRHVTLLTHLIQSPELNAANPSKVQQEVQQRILRCYLRELCRQFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7Y0</accession>
    <name>A0A8K1C7Y0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GST C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7Y0"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="27715" checksum="A78CC187AFCCF57B" modified="2022-08-03" version="1">MALKLKGLEDFVGLTVTHPVMQRTRPDDEDDQYCGWKFDVDGEFEGTSPDPLHGAKYIRDLYERVTKEKVPYSVPLLWDKKTDTIVSTESADMVRMFNKAFEELSPSNVDLYPENPRDEINDTLGWLKNSVLSGGFKKVGMAPDDDTREVETKIVYDGFDRLEEILSKQRYIVGSTLTELDLQLFTMLLRFDMFYVVFFKLPKRASQHPRLSSRHLPAPRHEGDGRFRTVPCLWQQHTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C806</accession>
    <name>A0A8K1C806_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C806"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="470" mass="52790" checksum="F62279A34256E6E3" modified="2022-08-03" version="1">MKVEIHDSDGIFPLNFDIITRVDIFECSLSTMDAVWDDQEFFEFADDDAMLQAALAFVDDAGMLKPLPDPIAAPNLALPTVQPADQEHTSTSPPLGNIAKKSAAESPPKTRKRPPSQCVRDELIYLRSTVKDLEDQLEALLQAAAEPDVVDEMWKRVAARQAKERQRAQAENKRLLAILEEQIRAGKRLERLLLGRNDSVPPILLAKRLCSHHFTSPLDDPALESQLMDQIVDMYRDTDRILAHPRFQSVSLDRICSIEIQNGQMGPQFVATETRMIPFDFQSTADAKWEISKKYAYPKRVILQEYINADEGIITRLLERSLDLPTGPSHYRARSVRRHFVEHDRVVIVGSMVMDALQVAGQSMQGVCLRTHAWVILQPATDAGVACGPQRPASLRKLYYQAEPEVYDDGMSAEERRTSAGVLSNFVLNSVQLKADLNYQMLENLLMDRLRGLAIEDAVDTRIDSLLGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C844</accession>
    <name>A0A8K1C844_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_011915</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455364" description="Cyclic nucleotide-binding domain-containing protein" evidence="11">
        <location>
            <begin position="17"/>
            <end position="2664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="594"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="701"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="781"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="815"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1098"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1131"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1294"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1323"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="423"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="918"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="1426"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="2379"/>
            <end position="2493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1740"/>
            <end position="1785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2592"/>
            <end position="2664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1740"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1770"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2653"/>
            <end position="2664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW58327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2664" mass="305274" checksum="38B8D7BB1E543F1D" modified="2022-08-03" version="1">MCALLYVLISIPFRIGFLYDPHVAHRVSPWKPDLTILTVMDVVTDAIGIYEFTEFYRAWKDAFAHLSESVSFELGRKLSKKANHRTKAPKISTRNRQGSNLGLTNNQAQWTLASIAPTASASAQVTSRRQKAIEISMEVIALIPTEIVVFAARRYNLLHVIRVTKLCRLFRISDYLDKLRRVYSERMWMQRLSFTGISVLLRNIALAAACCHYFACGYMLIAHQSCGINLDMCDVEIESSWVIRDALVGGSVVRKYARALYWASRTTVVLGYDDVTPVSDAETVYVVIVEVVAAVISTSILATFLFIFRNRNSRLAAFNSHVDNAREYMKSQNMPREIRRQVMSYFTYAWNTHHSLNSEEVLQSLPKHLQSKVVYTLKASRIKQVCFLMKESTEFINLLALALVHRVYIPEDSIIEPKINAKMFFVVRGTVTLSAFDGSHPKECQTGDFFADCCLLFPEKYEEKAIAKTFCELYVLEKSKFDEAIHHFYRGNEQATKERMVDTFEKYSSQLRKTKKLLGLRGGETEASSLGAGTSYLSKLGVTWRYAGSSFRIKWDLFRLLAIIYVAFEVPYYIMFISNHDAQKHFLVTQDMSGRYVVSLLIEAFFVVDLTLRSRVFGYVDPIVGLNVIDPSMVFMAYKANGFYTDLISAFPIALVMESLQGRIEDLSWMFRLLRLLRLRYVGDLLQDITEYYGISSKVQLILSLLMGVSLTLHMIACIWFEMSWLPLSWDDPQQGTALLGITRRNCLRMATNYQNCSWVRYDCYGHIGVSFPFEDTVSPYITSFAYIRSVYWAVVALTGVGYGDIVAFSTSESFFAAFWIFIGGIINFGIVGAMSSTLSSLMATEHHHVEKLNTLNHVMEHLGISEHLRGEIRRFYHHQFKNRKKVYESELLSNLPDQLCYRISSLLHAESTKQVTLFDSASHEFLEEVTGKFRHRTYQNGETLYIEGDICKEFLVITHGKINVFYQSKVIPIGGLHDGDCYGVNEFLLRQSHAVTLVAASPVSTSVMTREHFDIISRKYDEEMKDIRDEAFESWVDDKERLRRIARNFERLKLKPHVLSTTSMFYVRELFLLKRTEGKKQHNSSDAEAIQVKVTSIWNFVLTFWNTFNAFSIIFRICFHSHLYYSDLGFRSIVLVDLLCDAFFAMDIYLNLYYFDCEEVGLDNLLTRTQRNARYRRSALFKWHLAASAPIYYMNQHSMFVTSICRLPRLLRCTSLWAYIDEVIIHVQQAFPSQNVSSYLSPLKLLFFLLLGSHYAACIFFWISEVECERHPDYCWIEHDHLIHEYHHSIYSLYIRAFYWALTTLALVGSREIVPRNTRGTFWATFTCLGCSFVMGYILGELSELILDMDKEAKHHKSRIDSFEHFAKEHSLPENLRERVTLFFKIQFEHNQGKDLDEAVHDLSANLRLKLMHEIYGSAISLLPIRRFLSNAQVNNLALRLRTELFIPGDDIVVEDTFGSRLCIMRKGLGAVFWSESVTNVAVLMDGCLFGEVAFFLPNQRRIATVKATTSCEVVHIAKHAWNELWNNATTDTSDNHVQKYAMHAILDWVKCRVQCYQENTLTIAKRSNRHLLERRIKENLKSMMAPAKMMRTKVEKGRSFLTPQAIVLEKKAKYLLSQVDKYMAKRGELADQISKAAVQSRRSLNHDIMGLGQAVSGRFRSVRGHASPTKKSKKTLKTLDRNVGQFFAEVNPVNKHVTSHLDDHHLYLLEKECWHRYRYLTCLQRNVCDMMDTLLPQQTQPQTRLPPEASSRSSNTPRQPRGRRGSVLTRQSNRGSAMQLTRAHSFRTDDDPLVMRHERLKHLVGSRNHEGSPQKLFTTIPPPSLRKIARDSSGRFILGAATTAQPPDKESPDPHSPQREKILRRMRRCHSLPHFDRRYFEKIKHDDDQVQRAKRSAISGIESTLLGNMGINFDILQRCRRPKFSALYRIYRSYTQLHGGSASSGSSHGSALSIASFGRSHPTLQTRRSLVGSILLRRSTVGGGDNAIRWQKAMERRAPVTGSADLTAAAFHIFIKRLHKSWEFLMLFIALYHAVTAPLKIAFVHDLQELTGLSAWSGLEYVMDFLCLADVIGRLRRSSTLQHSIKTHKASTLASLPPTYEGFHADVIALFPMEIFVFAVHSYSDRLLYLDKWRYMCFFRLNKIVFSHRLQDLSESVFQYMVYDLKLPVIESSLYFLRSLAKYVLMAHWIACIWYGVSEKAYQVYSTSWLSTPGMLVFNNYHASSAATSAHGGAVDLHVISLERKYMRSFHFAMGSISTLFYGDVVSMNLIELLVEIMVILWSIYIYGALVGAHGEVLETHSRKKAMFEQNLSELQHYLLNNDVPKVLKKHIKQYYASIWRRRNGEEELAAIAGISRTLQEDVVYATLHRFAWKVSVFHSLDVHFLRALLVKLQYVICAEDEEVVIRGDVDRSMYFIAQGRILVKHDKSEITKEKGDFFGELALLYGIPRDETCIALSLAELYRLDHEPYEELLLDFPEYRFRNKHEWTTVEPPPSVLASLMQTMTLNGGGGSTSSVRLGDELADAAMGAAMTPSALLDEEIPRSFIFKSVLRLLSLFTHIDSLEAKEIIYRARAGARLHLKRLASIETSRPAHDSTAQLDPFVASSPRSPVPEKSTNEYNDIKESATLPGMAEDGKDTGKNGNAARAALFKREWTRSKLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8T7</accession>
    <name>A0A8K1C8T7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8T7"/>
    <dbReference type="OrthoDB" id="121865at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61730" checksum="D18A959966A6CC02" modified="2022-08-03" version="1">MSAPPVPQQEATEYVVTTVEPLPIVDISVTLGAWLLRRPDEVRLNKRIIAITTNHITVMQVITAIASAFSAATQLDYNATAVGVYSIGSLVIMIPVLIVVSASLSVDLLFLTIQTFEFWFLTFLNIVGYVCSVMMFADDRMLMSTMSVFYLSLALLIDANVYSRQWLVWSFVPASATFGAGLTALILHYVPRLAPAKIRIGPRTTMDALDLAIHCFMTISMFFVVKLYRSRQLIFPIRSPIQTIQCETYYPSCHLVPSGVVTSFHIQQSTNSKRDATMALKRLAMNKKDQPGPIDTNNTLVPFKRLSRIQWWLNPIGFTGLLCSVLPFHLYMGSVNAAKTPSTAEALVATIGLLATLIFFTIYVIQAPLVLLRRLFRCLDALFVSFQFLLVTVGVCDAVLWDRRVLFVLTPFLWCSWIMILDALTPLTKRRLGYQRWFTWIVLLALLAYPVLLVYWIFYSDAKLQNRIFFRTVLFGTTVQMEAYSLLVSRVWTVWIWMGRFLWRELFRPANAFKLLKYRVEYAVAARIRSRVIRSVRPREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8Z1</accession>
    <name>A0A8K1C8Z1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Actin-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8Z1"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="51678" checksum="15DD83AB223779B7" modified="2022-08-03" version="1">MYAGNGGQTSVNVGGSGGGGAPHASGGSSAMAESNDLDALVFEFGTAKCKFGYAGEDFPRVYESPVHLADGEDARACTRRAALMETDYEAMAQWLFDAAGSRLQTKLSEHPLLLVERPFAIPDELTQTSGDDDDAVNKMKKPSDEKTSSKKRDLKARERLVEVLMEQMDLPALFCAKSAVLTCYANARTSGLVVEMGATYTSVTSVYEGYAFAYPKSQMQLFGGHDLDAFLRYKLHAQLNAPPSSPSTADGEAAPSPAKKPRRSPFYWWSRAVDAKESGLCRVADGPFDEAQNTQLPKISYELPDKTIVQLGTERFSVAEQYFTPPESANAEGGDVVQTYDDDAMANELGVKRGVNLPQWICETGAMTTEAELRKELFQNVVLTGGSSSFENLPARLEREIIVAQSAFQSGTPGASTAGFGGGSGLGNVRVKLVAAHAQERRIGSFLGGSILASLGSFHEMWMSKAEYAEHGAALIHKKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C986</accession>
    <name>A0A8K1C986_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007179</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C986"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF176">
        <property type="entry name" value="HEAT SHOCK PROTEIN 78, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="82"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="491"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="10">
        <location>
            <begin position="660"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="296"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW59034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="763" mass="85204" checksum="4E1B9236A3BDEBC8" modified="2022-08-03" version="1">MWRRQLRTSRQALRLASVRGFSARGGPGPSQPWINPDNVPRGESLTKYGRDLTEVAKNGKLDPVIGREEQIRRAVQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIALGEVPESIKNKRVVSLDLAALVAGAKFRGEFEERLKAVLKDVEETQGEVILFIDELHTLVGAGGGEGSVDAANMLKPALARGSLHCMGATTLDEYRKYIEKDAALARRFQSVLVPEPTVEDTITILRGLKEKYEVHHGVRIADSALVSAATLANRYLTERKMPDKAIDLMDEAASRLRLQQESKPEPIDKLDREIILRRIEIEALRKETDAASKKRMVALEQEVEQLSQELRVLMDEWNAEKDRLEHMKESKRKLEEARRELVAAQNNGNYARAGELLHAIIPKLEQEVAEEEKEEEMATKTDDSTALKKTYLGDAVTSDHVAEVVAQATGIPASTLMAGEKQRLLKMEEYLDKRVIGQEEAVKAVSNCVRLARAGLHAHNRPLGVFMFLGPTGVGKTELTKGLSEFLFQSPQALTRIDMSEYMEKFSVSRLVGAPPGYVGYEEGGTLTEAVRRRPYQVVLFDEFEKAHRDVSNILLQVLDEGRLTDSQGRLIDFRNTVIILTSNLGSDILASLPEGESSSRAETDVLSVVRGHYAPEFLNRIDEIVLFNRLRREDIRGIVDLQLNQVDKLLEEKEMEMQVDDDVKDWLAAAGYSPLYGARPLKRLIHHEVLNPMAVKLLEGSVGSGKPIQVKMNPEYDQELVRDPQRAKALVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA74</accession>
    <name>A0A8K1CA74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA74"/>
    <dbReference type="OrthoDB" id="47432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933:SF11">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="280"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="331"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="677"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="540"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="817" mass="93023" checksum="F6C919722E1E6145" modified="2022-08-03" version="1">MAAFLHVSAALARRTGAQLRGSQRTPTLLTALAAQYDQQRANISTTRVVEKRRGGNSAFVVKTSKFRSNKGVRTKDKLKADVAPHKTHVDRMRELKTVGRENLRNSKLWAQLEEDEELNQELDNVFEYLKNLGPEGEYEYQPDVSLKDLNEDDVLAKLNAIALGDPSVLQEVTERLTEEEGDDGLQSMHELSVDDYNFLMRVYAEKGLHDHATALLARMEKNLETSVAAPFVAKSTESTSTALSLTASLDAVPHRIAPDVKTYMYYILSLVNSGASAPATAVRTLGRMKERGVQPDVHTYNSVMNVCAKAKKMQWAYNIMEKMQLAGLMPDQATFTILMHAAIADGEIDKAFETFHLMRSRVTEPDVVSFTVLIHGYAKLGRIERAINLYEDLLDCGLTPTHVTFNALILACAKSHYFAPKAIEFYREMQELYDYHPDLFTYNNVLHACAKHGDYIQAEEILGHMLKHNVPLDERTYNTLLNVYARAQIRGVVTQAPRNKAPPAPLEEIYQEPLEFDDDGRQIDLTRPFKEVNSLKNWNYDGTFDEEDDEDDEEEQYAEYDDEDEAASVANDGMSEEERSELEKIRAQDQLALQRMDDDFTDDLMLRPMDLSNFGLFQTQVIARAERLYREMTEEKELEPSVVTLTTMLSVYANALRLVRAQEFFAKEFSKHEVEPNVHTYRTLMQMYVRSKRTQKAEELMQEVKHKIAEGELKADAITFGMLVDHYARHKVMRKALVLLEDADALHLPIGERHLKKIRKLTERFGIFTALIPEDPDAVITAGSRSKLMEKRKVRAEVLAYNEKVGKKYLLPASVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAG3</accession>
    <name>A0A8K1CAG3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAG3"/>
    <dbReference type="OrthoDB" id="109083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="205" mass="22203" checksum="694D13BBA12CDCB4" modified="2022-08-03" version="1">MTKHSTRIGSLPASTGGLATERASIIHHVDEADEQKPTLSVIAVNTLSLDSTSTWELADALVAILTESDVQKLTVVASLHLTQAKAHSVSQDNVYHAAFNVCDDRSPVYKQLDSTWEVKDEFLSSMMHFLRVDQSIPTHLVVAKGYKPGRDGAGTLDALQTLAPALETYFEGSASADVQAAHLDALMAQKDEDRSATSTHNLLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAX6</accession>
    <name>A0A8K1CAX6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAX6"/>
    <dbReference type="OrthoDB" id="69983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="462" mass="51896" checksum="8D690C9972A69165" modified="2022-08-03" version="1">MSDDGCEMALHAAMSAFIDEFRLDDHEETETQLPDGGALLFPFVDDSNDVFSALEGDDCPDQLGSTVYTTAHEAEEPSQSHGAHTLTSLTSGAAGAMAKTAKDGKGRRWNTKREELLYLRATVDELEGKLTKLRAAEMKLESADTEPEELVDAVWEGVAKRQYEQRRRAESENAKIRVLLEEQLDVAKSLGRLLATKRSNIELLSSAAKAPKRHRRYRSTSPLGKATLIEDLLQTLGEMYEQVDELLKDPRFDPSTIPTITKHPLREVRLRSDLTRGTFVEIVEAKVLAIDFQTFGEVFWQNIDPTPKPHKHMYEETTHTSEHSFARSFEGVLTVQHATGEIRGHTIFRRFIEDTRIIITVCVLAEPEKLLGKKLEGILIRHQIWNVIQQLPGNRTCFQSYNACIPEVYEDGPDDRQKVGVVTNFILSTIDFHVGFTEQVLTNAMLKHAASSRPNSPEAIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB53</accession>
    <name>A0A8K1CB53_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB53"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460005" description="DJ-1/PfpI domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="260"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="48171" checksum="4491DA61839C4A23" modified="2022-08-03" version="1">MVLDRALVIGILLFQNVTTIDYMGPASYLEYLEPMVGQKTEFYTISEKAGGPIQPVHFSPVVASVGFEDAPKKWDILIIPGGTGTTLTSKNQKYLDYTRAAAESATDVLTVCTGSRILANAGLLDGKSATTNKVKFNEIAAEVPEVNWQAQARWVVDGKYWTSSGVMAGIDLGHAYISEKYGKDVAEKMSKTMEYVPNTDPSNDPFYSVTQGTAAPHAMKSANATAPPFRIGIVLFEKTSTMDYSGVNNFLELIKFMAGKNSEVYTIAEKAGAGTNPLNMMPLFASATMETAPEKFDILLIPGGPGVDAALKNEKFMTYVRQAAEKATDVLTVATGSRILGATGLLDGKKATTSKMELGKISTELPKVQWEQQARWVVDGKWWTSSGSASGMDMGRAYISAKYGEELAARLADLAEYTAILDPAKDPFAADAEPVGSPAPSKCKVKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBB9</accession>
    <name>A0A8K1CBB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBB9"/>
    <dbReference type="OrthoDB" id="2161133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040174">
        <property type="entry name" value="RNLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23357">
        <property type="entry name" value="RENALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23357:SF1">
        <property type="entry name" value="RENALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="116"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="39605" checksum="4FA09715F2ABB31D" modified="2022-08-03" version="1">MARVLVVGAGVTGAALARLLHDAKTSTKYAGQVLVWEKSNITGGRMMARSFRKNRHVHVDFGAQYLTKFKSANDDIRELLVANGKLVNFEDSRIAQESSRAPSPDAEHTVSPDNLGFRSMVDFLLSDATVQVERGVERFDITSDGQVTVYSTDGHVETVDDLVLTCPIPNVLSILEKSHFQPAPEVLAALQAVQYSQRFAVAYLFDQSIAKSVQDLQWTSKYVGAEEDEVVRFLCWDTLKKGTSTQDGYALLVHTGVPFGLQHMDAKDKNDEILATITRSVQKLLPFLPDPVDTTLHRWRVSQTFKPFHDPASPSSSVPALVLHASPRIILAGDAFLGSGFDNCLLSAKHTASILLGPSSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC78</accession>
    <name>A0A8K1CC78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC78"/>
    <dbReference type="OrthoDB" id="59517at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00081">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001767">
        <property type="entry name" value="Hedgehog_Hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050387">
        <property type="entry name" value="Hedgehog_Signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889">
        <property type="entry name" value="HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889:SF31">
        <property type="entry name" value="PROTEIN HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01079">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434856" description="EGF-like domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="458"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="714" mass="79037" checksum="A6F1202DA9710580" modified="2022-08-03" version="1">MDMMPTIRVVLMLLGVVCGARAQILQCNATTQSQDSLARWSLTTTGLTFSRDSHAAAVFDGKIWIVGGVSTTYYTKRLERTTTRSDIVYTSDGETWTEVFEEAPFRRRYGHTLTTFTDGSDKKERLVLLGGFSPEPATDVWTSTDGTVWTESAAAVSWVGRGYHCTVVFNNRLWIMGGSPLNNDVWSTSSVLNGGWTQQADVPWSPRAAHACTAHKVVGNVTIGETTIEEFVFLTGGWDETSLQDVWRMNKAGEWKQLLPIAPWKRRAWHSLVSFDSRTRGDIVLGPRLWLIGGGIIGKGVEKMFPYTDTWYTRDGVTWEQSSSDASGVSTAEWSMISTRDKQICMGKWGHVVVPFYRMVKRSFYCGATCQDETNTTSVANQIIPMCRPALDLPSPPVKRTVMVQNTVVLKTLYPDGCGYCNGTDADRYVNNTKVPALYLIAGNVGTQKVKDVFVSNDAMLCEHNGVICSNKGTCTLGGTCLCVNGKTGQFCDGDLGYIVLDDGACFPESAQVLTRDRGLQRIADVSVGDSVLAMEADGTPVFSDVYYIPLDSDPRVQTQFLRVHHQSLRDGQRLPPLELTPAHLVYTQPNDSVRFEVKPARELLLDDRLIILPFDATSSASASRVVALEMVARRGPTTLYTMTGTVVVDGVVCSNFADLYPRLTPTQSRDAVPFALFTPHRVLFRLVPHAATAQWLRRLMHHVILPLWQVVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCA1</accession>
    <name>A0A8K1CCA1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000212</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="431588at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028089">
        <property type="entry name" value="DUF4455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027914">
        <property type="entry name" value="DUF4456"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444:SF14">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14643">
        <property type="entry name" value="DUF4455"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14644">
        <property type="entry name" value="DUF4456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4455" evidence="2">
        <location>
            <begin position="124"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4455" evidence="2">
        <location>
            <begin position="680"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4456" evidence="3">
        <location>
            <begin position="1445"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="958"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1780" mass="200467" checksum="B34D44DDFB2DC5D3" modified="2022-08-03" version="1">MDKRRDGGTTSSTSASRMDLQSRAEMQLLQVLHQKKAKSASGYLREERQRVEEQEENQQKRLTTENMKQFRIGQGKNPAPPREEDEMIAAVRQLEHHITTRIKVPDTLTPEASEENQIERNAVQRRERHMAGLQLYTEQVKTISDDIEVALIQSADEIKDILARIDTQLHQAEQTFQDDALLLRAENAEIMQMWDDMLAICDGRTREINAFAVRLDQIEQTRIQRVGAGLTALTKTLMDTAHALPPEVERIIESEAFELNVVVVSNRKSYADLIARMATADVDVMVETRLKWEQGQEHWRQLRHQDAIQRFQDALNSTAFTNPDERQHVVVNIRAYQQQTHDEKRMHELKKLGAAGATLTSVMAQGVLDNLSTIQREEEEQNAAFFDELRLLHDGKVLEAQTLTEALRLEVHGFGALAPEGEISVSKDTLMELLSDESLEEFFRMAGGLRSELDQVVKRLEIQELVYQANVAPLRTSVDVLLSAVPLESVMESQGKGAERKATQTLLERMRKASKTELVQLLPSLQTPLAMLRNLSDMNDVFKAEVEDIGVQLRVLMQENEALFGEPGDTASTTSADSQHTAESSGRQTADKGKTSMGPPSSAFTGGSSSPTNRTMTLSGPGKGLSASSVSLLAASIDIQAIRKIQRRVGTLVYVTELPEAFRTHLRFIATQLALQVRANDVVDAVIARECHDLLSHREEESKTFLKEIGHRIETQSALLHDQSERIAKFFHTVALTMEQSEARVEYVNLSALDLLDALKDHDDERLASLEQAFAASCARLRHAPDDATLQLEFEACTDLLQQIETAYRLYHRQGALAASHHMIATEKQHERFLRELCELFGLSAPSLPTEPTSTPFDVDLFLSCQYIEDCVSPKPPAESEEPGTARSQQSSGEPSEQANYSADPKDKGDTTSKKRGKGKPEAAPAEVPKERFETDFGLVLAVESNVAALVERILTQKSKDDDEESPGSETADNGGNVAADASTLGETVESVEEAPEVIAARLARDERLRQVVQIVEESFLVLAIPSSFQQELVDGFRRVILTQFDRNFQKHTTGASDLNAERQRDCNLLLEERLRMHWPRKGRLDVQLYQPRIGELYTHRQRLDRHLRTMGKKAKTQQEAFEKEVHCLAAYIEEIRVKQLALQTQLPMQQSLAALQGVEVKSKKLLSEFRSESTEKLSKLRDLVTQDSTALTASAQDYLRVCGMQLFPDLTSVEVISGRDYHPEEVEGVGARLAELETQLRVFIDGRDPIVADLEEKQRTVLGAAQEFKTRYQNCLQSLSMKEGLGQKYGVPRRTAQERFRSETTRADEVSARIDVLLASLQSMIESQRAVKTIKGIPSTDLATQILHILLLLRAQLYHRGVYFGFLKNLSQLEPTGVRYESGGVAGRPVFSDQDVVHDELWIPEVPFLEYVQQVAAKCREDTRALYKQEGKLEELPSSGVPVALDEYLTAQAEKARAYMIQQELKYREQIDTFGELLALAPETALIDLLDRTKNRITSITGEVVESLEAKYTQWMELKNKYTVELRPELCSPNNATQLQALCGREQARAEETLSGLRQTRAQLLEMMIKASKEYELELLAMFKLFLVILDSSVMTLEDLKPFTGEELPKLKRKTLKRLRKLARIQEFGDPREVKRSDEEMKKLIQLGEVPRFTKRGWPAIPSFGVHQLWSTKITELLSDDEAMACTSVDTALSELLNVSPTTTEDGSSVALLTHAHRGLFHGRDETYAEFCEFCKTHSDKLLVTLQEQVRDEVKWTESWQLGIHKVRRRAQPPSTEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDN2</accession>
    <name>A0A8K1CDN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDN2"/>
    <dbReference type="OrthoDB" id="272977at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="2 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="5">
        <location>
            <begin position="3"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="927" mass="104612" checksum="7EA7B508E3E1FCE1" modified="2022-08-03" version="1">MQGIDATFFDKKFNVSRYMLRYVVGASNDEIRQEQLQRVAKFRAIADAEIAGVIDQNYTNFNTSLARFTVISNQLQDTREKIREVSKRATDGKNILSSKTKNLRELLLQKYEAKKVIDIINDIQYIEAAPSKIHVMMSERNFTGAVDMFTKSLDLVFSEKLVAFHAITGVRNTLMECKQSIEDNLVQELHHTIYMKGAFANFSKANQYSMAAIEHELSSDSFLDNEFDKIMFQSNQRDNDSSENAFAESNVALRGTNTFNALESAVKAVKKIHREMEVIGSLKSSLENELNEVVIEISLICRGIFNAGSYTSFENHFTEKKFGKHDHSTNFQTFLRLLFHVLRRIAQRHYLVAAYFNSNGDSYNYGMPDILHRITSLLERVLSDYLEELTATEANAATKDTDFSITSGDLFKLSRNKQPDDSSGMRLMLPHDYHGKVIEETRTRVCEASVFHLPVVYDDLQQISRDLQQFATASSASSSATTVFSSFLNMFIAMKWIPKVKAKAQQFLSMKYRGTGSSSTACRLPIPSDTSYQPPSIESLLFIAGELREMIIKMPDHLTELIGVLDATVLKWLDECAIIAKDIREPTLNHRQIIQSVSFSELLAAFHKYDRYQKAKRNAPIPFQHSKVAPVNAGKTAANTGVKPASEIIRQKEYELEKESYDPDAWSSTKGLLMDNSRIAMMAYINSACDYIAEFLQTVTTRGPRATGSFSQAPPPSSTLLGNSTSSAALQATSWKCSALADECLLFLRREIRLHCFYFLTQLASQRYDLKEDQATMAQDSVLCLNINLSAIEHALRPYLSSDKMALVFDGIDALLANILISNLQQMQGATMTKGGVQQMLLNIGALHQGLTGILYSYPTVGRAGYHFEYAKRYYQLLLLSETQLELFLLDNRKAYTPDAFKSLWRVETPHRVLGKGSQNKLDSLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDR4</accession>
    <name>A0A8K1CDR4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012745</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDR4"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="65565" checksum="2126F5AC014BEED3" modified="2022-08-03" version="1">MDRDFQYGASRLERLSVAESITSTAFDSRSQDDPGTPRVSYVLPASPITKTAPDGVEFSDGEAQTIPELPQNGALRAGDVPNLYSRRYIGLLVQYAAIGLIYGALPRTVYPFLNNYLHMNGYQTLSARVLLSMPWSIKVFIGMLSDCFPICGSRRRAYMVLGWLACSAMLLVLVVRSQGPPFYVDRSLRGQDLSSLSKDELVGRIFWAAPEEGATYIVFMMLASCGYMLADVASDGLVVEFAQREPEAERGNIQSTIYLVRSVFMIFAALLVGFGLNGVDYGGSFSWSLNMSQLLLICAILSLGAIPTALWLLHEPAVAPEDTRSVRAYIAQLWILFQNCAMLQIMAYRFFSGIFEGFTVTAGDPIQRYWAHVHPLNESLFSVLGLCVFSAALYGTKRYGLQWNWRNVIAGTLVIVLCIDAVVASLTIWNVVRSQWFWLGTPILEELPAAVNFLVSTFVVVEMAEQGNEAAVYGLLTTISNLASPFASCLSKNVNARFDVSVDDIISDSTHVRWQVTWTFLIAYVMKLFSLTWLVLLPRQKRETQELKQRAGHSRLGGCLALGIGAFALIWSITTNLMSIFPATACLAVAGGSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT7</accession>
    <name>A0A8K1CFT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT7"/>
    <dbReference type="OrthoDB" id="105025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="45643" checksum="660FD57DF7E38DE5" modified="2022-08-03" version="1">MKSHPSCLDVFRPLNLSASEERAIADEAGLVIQRTLTQEAEFRKQGGRINLREWKQVRVEDGLAVYKQRKVPRTGYSSSMTDIDGDQEVSVPELLSNTAQSAHSGNRWRFASMDLLEFATTISSSSGSNSGDSRVPAMLAAGHIEGKLEDAMLGIFDGDEHAWKVRAGLIKDKFDEAQILATIRAPSEDEPFNFLGIKWFSVEYPKVVGSFIQKRDTLVMEALGIGIDENGGKYGYSLLHDFRHPNLPELKELGMLRSKLSMCFIFRQTSPTRVSLYSRGFVDGGGDLPKSIAIAITALSIVSNANAVETAYSRKLAWLVNSQAPQRRIAREEQRQSSSCRSCDKTPKLRGLTECHACGFSFCTKCTVHRKVVVGKHDTSVHSLSFCFGCVLQAKGLSPVEIARVTYVPSSDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH01</accession>
    <name>A0A8K1CH01_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="537"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1619" mass="179930" checksum="3AB741683E2B93A0" modified="2022-08-03" version="1">MNCVKGEIHNVLSMMRVNARWASADRFTQEIPAATQSPMMRAFKQLHYELQSVTDLADVDTVTYLLPFVMVIESDKTSGFITGAAISSLNKFLLYGLITGDSLRADVAINRIAVCVSQCRFEETHRGDDEAVLMKLLELVEFSLRCDAGHLISDENVWKMAQLCYSISCQPRSSEYLCRAAENTLAHLILTVFDRINELEPRRGEEDEATDADYESRPPSRGGNRRTQRNAGYGIPLLERILQFLSTLISPTAKDEATCVFGLRLINIVLETAGTGLGSHPGLVSVLQGDLSKYLLQNSETEDLAILSLTLRVVFNLFNSIKDHLKVQLEVFFTSVHMRIIDSPSCTHEQKELALESLLEFCREPAMMLDLYINYDCDVHCTNLFEVLCKSLARNCQAMESPNGNLNALTLLCLEGLLAVIESIARRCPLGAAGSAPNEAEGAAPGSTNGTTSNDVRGLKGSDLARFTEGNVNQFRTGPPSDISLEDVSPLSSVRDLMQMVMSGSESDSDSEHGDVGSSTVDQLAWLHTARERTAEVLQQRKRAKKRYALAAEKFNTDQKKWISYAQELELLPEEVTAESVAAFLLHTPGLNKTLIGDYLGEGPPEKYPFNEAVRDAYLNMLDFREAKSLDEALRMFLAKFRLPGEAQKIDRMMEAFSKQFHAQCGSSGPLADADAAYVLAFSIILLNTDLHSDHILKKMTIDEFVRNNRGINAGNDLPVTYLTTLYNNIKEKEIQMQHDVSDIMESSFSTVDRYSTQWEGVLKRSENVVGASFTSNASILKLRAGLYEKDMFNLISEGTIKCILLAYEKTCDLTNMERALEGLSNCAKIALYFDLSDVFNKVMASLSTYFLTFAHGILMGEKVYMPPSSGGAAAAAMRRSQRRSEDMHEGDAPGSVLEDGDGLSGGSAIEVDHVKGAKTRRALLALKLLFQFVQKRQESFDKAWSSVIECVLMFNELDVVPTSLVEMDDFVDSRGVPLPPIQGGSQSPTANQTANGAGQAGATGVSGKTRERSRRVAERQAAIRSRMKSMSSGSHTSYGSAQPGSQSGSLWGSLSSYLWADEEKVDEAFSRVSKMLRDAVSKLGGGILEKENWLRMVRRLHERSVSSLLETLLACRDPFKGVMRPTDGGVDAMMQENAILVLELSVDLILVNSHRILPLKLWDPFHTYAERILSTPLKDLRMPSLAERVVVHILRVSIRLFHDEKIRPKLMATLQMLLEMDEDMYRVLSDRVAIGINMLLKANLVYMHDFHDWPVLMGILENVVQYKNGRAACWESVKVLAEGGHLNDENVTLWIATCLRFVSQRTPYSVDALRLLQGLATSESTYKMDGHAWLEVMRVMLSYLNDERAPIAKTAWECLYNSLLLPGVPVAKDTWKHCFDDVIFAFDDQVNEGMWRHMREAPLYSVTLLSKTFLHHLPVLAELSSFDDLWLNVLRRLSNKLVMQAQQAATSSHAAVVYETTLQSLYNLLLILQADHILDRPCSSNPSQTLLDATREVVDQAIPHLKEQLGLVPEAIPEEPQPAVIEGRLEETEKAVQNEVEVEQASEAVGTSVETTFDQETQDTQVLELHFQNAEITTVEATSALVIEAATSVEAELVATPKSVKSEEIILDEISEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH26</accession>
    <name>A0A8K1CH26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 5">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 5"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH26"/>
    <dbReference type="OrthoDB" id="275783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051500">
        <property type="term" value="F:D-tyrosyl-tRNA(Tyr) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.80.10:FF:000001">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="154" mass="16822" checksum="6857447CC51B25D6" modified="2022-08-03" version="1">MRVVLQRVTSGSVRVDGEIVGQIGKGLVCLVGIGRDDTEDDAEFCCRRLLNARLWPDDKGAAWKTSVASNGYEVLLVSQFTLHGYFAGNKPDFHLAMAPAPAKELFDSFCDRVRRTHVSDKVAEGVFGAMMEVALVNDGPVTMCIDSKDRKGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH61</accession>
    <name>A0A8K1CH61_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DONSON family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH61"/>
    <dbReference type="OrthoDB" id="534063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024861">
        <property type="entry name" value="Donson"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12972">
        <property type="entry name" value="DOWNSTREAM NEIGHBOR OF SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12972:SF0">
        <property type="entry name" value="PROTEIN DOWNSTREAM NEIGHBOR OF SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="60116" checksum="F59A52E3F1F9038F" modified="2022-08-03" version="1">MAGQDEEHGGGTPASAKKRLLPMELRRRRRAAKLQITAERNVATISATDMLKDLDEQETETQLPPETTVALTIEAEATSVQPTVQEPSPQRPPPVTVNATAKLQSLLSRSLLDRKRQRSSIRDVQAELPMAMQAAVFPLDVAPKSKIVVTMSFPFPFLRPRSTPMATAMATASAQQLPSTDPEIRWLQATHYYVHPASPLPPSLSVTNDKQLEESEFYVQRFCTWQESFRHAYFGFRRQSSQTLLYLRCSEFVACFYRAVPDANDTRRASTSLADLCREYQGQGTTDDEDKSATSRSKSRLCAVVSQSNARMRKELLARNIVYNVPFNLKAMQKPVNDMSMLDEEDHALHAQTFAPSASSVPSVHGPDSLLLFDGHQSVHGLYEYLLNRKPLSNQDVPEVIASYPFSNAAICPLSVRYMGRTATTISSKLEAPSTSDPADATNFRIEITGFCSAPAIASLLDSLREGRQGSSDSIKIVMETASMAERLNAVFLKAKDPLTLQRSSQERDEWKKELEIAKRRLQAVVCAIDETKLELDMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHC8</accession>
    <name>A0A8K1CHC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phospholipase A2</fullName>
            <ecNumber evidence="2">3.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002517</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the H-rev107 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHC8"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070292">
        <property type="term" value="P:N-acylphosphatidylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051496">
        <property type="entry name" value="H-rev107_PLA/AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13943">
        <property type="entry name" value="HRAS-LIKE SUPPRESSOR - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13943:SF77">
        <property type="entry name" value="LRAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51934">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="LRAT" evidence="10">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="280"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="40475" checksum="F0292420CAE282F2" modified="2022-08-03" version="1">MERFVVGDIVRFHRGEYSHVAVYVGHGHVIHLWSPSRERAFSVRIDSIRHVLNCNQPNASARNDESESDDDAAVEEPECFNGEMDARMLQDHGMDPFSGEEVVRRARTRLGETRYDYLNYNCEHFVTWARYGVGASPQAASHTNQVLAGALLGAAVGGMAGLLIGGAISLFSKVNSLSASSGGGSIGRLAALPDDTDDRNDDEEVTTPPSPSRLSRRRQERERLLESVFAIQLGDSAGETEFEAWSAARHRSRHESATLPYSIDRHNALASRLADDKLLCGICFYDLQLTRAVAFPCDHFSCVKCYLALVTNADGHKSCPYCRMQIDDEQMIHRSTKLEARSRIVWEEEAHATLNASLATETTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHE1</accession>
    <name>A0A8K1CHE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHE1"/>
    <dbReference type="OrthoDB" id="63102at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10751">
        <property type="entry name" value="GUANYLATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="743"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="647"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="857" mass="96334" checksum="F3ADEA9F581FF64F" modified="2022-08-03" version="1">MELDEYVPLCTAAAGSAELRLRGAGIDVLESSRHEARRVVLLAVLQREGVSTDASNEERGLYITTKSVNPHDVDAAVLLCTLRHVNLEEEPFWGSLLLLVSSHLFVAESGPISSTSFGSMTFLSDFSQWQVLETPSGEENSVLLREFMPSLTWVALDLKIKDMEGLETPSKYFEYKLANPPMHSGPDVEAQMLASGYFTTRECIVLKTNTLQTPNGYTAPQAFTSPKILSQAMENLHHKVFFGRHLSGGVMLHLLRSLAHCISSKSPIVIQRVVQNVHLNYWKLLLESAYEKYTDMIHARLGVYEKVEFTAEYLVDITERKLQNENVGVVNAGQGQFSTFDEFGNLKRQTSSTSDTASEKASANGAPLNTGIFTFLKDRAERAFTKQFSRLSSTKSSSAAATATSAAAGLNHIPEDEAADEENEGEDFKSLWNPEDILAQYNAPIKNYPVPLEYSTMVCEAMPVEVSKLEDIHREALNDAKNLIMPFLYDLRASSVQLSELACTIDFHVGKRNLFRRIRVVKERFALANEAASTLFCAQLIDYLHTVILRKGERDHEAQQSNPRYNRATSSVMIPQGRDGKAAAPLTRLPLELLTYKNNIEALISQYNFVSRGPMASRVMLGFFQACVRKRLLALAQKQYNQFAYASDDKEQRLTELEETLEATQQQVVQHQKGSEEAAMQEARNIADIELSHKDEILNLQDEITNTNEKIEKALNDQQALYQRTMQATRKTINTIDQVAVKNRGFKGYLERYEKGHVFSKSWRQYFYVLDQATLKCYKSKSAYEERDPPCETPITLTGYSVVKSRTDEMKIKLVPPEAGQMLRFRAPASVGRETWMKKLMEATQITSAPSGGRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHL1</accession>
    <name>A0A8K1CHL1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHL1"/>
    <dbReference type="OrthoDB" id="76533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454477" evidence="1">
        <location>
            <begin position="19"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="311" mass="35326" checksum="381C046E5B879666" modified="2022-08-03" version="1">MALIASAWKLAIITRCDAFRACLSAPEHALVESLDVQQYGCLKAAESEQNGGKESWGTTRDTHLERYKKWKLDDDKIDELTSVREDEGSVLHKVTPLVTDLRFFARGKRGVLYAAETIDQGDPVVVKFAGDPRASTSSAVIAGCWVETEAKWIRVMNRMGIGARLVASGTGWLICERLEGHNIVEFLTETATNATVRWVLREMLCQCFTMDMMGVNKEEMTHPTRHIIVHIARSAPQRWQCTFIDFEKCQYTKKPKNVTQLCQFLSSPRMTGLFERHGITWDVQQLRQRTKQYKQSITAESFGGLMKVFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHM7</accession>
    <name>A0A8K1CHM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005266</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHM7"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035440725" description="alpha-glucosidase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="12">
        <location>
            <begin position="37"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="991" mass="109894" checksum="DD1F0D559119B221" modified="2022-08-03" version="1">MLSGIGSVRLAQILFVIGCLTAHAQDLVKEDDGFGIVTVLYKQPLWPETNFHFNNHSLGWTAIPGYAMQKSSYGGNYSAADGWWEYSLKSSQLEFCFNDNNGIWDTNDHQNYKVNSAGTWALVSKSTEVPAPLPPTHISGAGYAVIGVEETGNKITLQLLANPTSEPEQFGADIKELVVDITKLEDSVRVKITDKNAKRWEVPLDLYSKGGLSKESGSGGQGQQGQGNTKSNLEVTYTKNPFTVKVARKSDGYVLFDSSKLDLVFKDQYLQIGTDVQSDLNVYGLGESTRGSMRLSPGEKHTMWARDQGSFDRNVNTYSSHPFYLGLNGQGKAHGVFLLNSNGMDVTLEDGRLIYQVIGGILDFHIISGPTPSDVVTQYTSLIGRPKMMPYWSYGWHQCRWGYKSVSALREVVDKYAENQLPLDVLWADIDYMNRFYDFTLDPVNYPQEAMTKLLSDVHSKGQKFVPIIDPGIPDDETDIAYKRGLELDVYIKDTTGKPYLGQVWPGPTVFPDFFHPNSTGYWEEQLERMQKMIDYDGIWIDMNELANFCPGTSCKRKEGVQCPNTGSIDVVTSCCLECTGDGNKWDNPPFAINNGNSHDKIFNKAISTSSLQFGNIRQYDSHNLYGFTESIATNAIVEKLRKKRAFVLSRSTFPGSGAHAAHWTGDNAAQWNDLQWSVTTIQNFGLFGIPMIGADICGFSGNSNMELCARWTALGAFYPFARNHNNFWSIPQETYVWPEVAAVGRKFIGMRYRLLPYLYTLGYQAHLSGTPIARPLFMEFPEDANTHAGIAIQRQFMLGSALLVTPVVFHAATSITGYVPAGTWYNLFDYSHLNSTGQDAVWNVKLDDMPVYVRGGSIIPLHQAGAMTSEAARATPFDLLVALPSDGKASGQIYLDDGEDIEGVSKSTVVEFRVESGKFTSKVGLNGYKDAKTKNVSKIVVLGVSSAPKSVTVNQGKPSQDFKYDGEKQVLEIDLKEKFNIAQALTVTWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI05</accession>
    <name>A0A8K1CI05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI05"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436588" evidence="2">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="132" mass="13496" checksum="CE4B56805A1FC8B0" modified="2022-08-03" version="1">MLPRRLVLLPLLVLAFSCAVAQNTNDITTSNTTAPFVVIVTSQPPLDDPVVTGTPSPVVETLGSSNEESDPVVVPTETPTPGPIVVIIEPAPANASTTSAPPAVESSDSLHEPCIIQIIAAPEPATAAPTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI10</accession>
    <name>A0A8K1CI10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">26S proteasome non-ATPase regulatory subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI10"/>
    <dbReference type="OrthoDB" id="10250600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019538">
        <property type="entry name" value="PSMD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554:SF10">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10508">
        <property type="entry name" value="Proteasom_PSMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58013" checksum="7D382B6603ABC9F5" modified="2022-08-03" version="1">MEPTALWIEVERFQEARLATTAGVYTAAQEHAMVQQFLSKVPLEALFQLLQSASDADDQQKVKVVCTCLDRVLSSDGAEGMFFQPEMLPFILAGLRHDERRARVLTVNQLIAHLQKKPTVEQASALANPLVLDEVCSVMADEEVEVASKASIVLDKLASLEGGDLYKPVIDALKTITRSSDMAESSVEYMRYLEALANICEQKEQHMHYAISTHAAEVIINCFKSNDALFLMNVLDLIPKLCQTQTGIQYIFESGTLQSLLGMTQDPLIGDSALRLIGEISATAAKLNVESWNWNDPMLTKAFLSTIESKIESTDAMQQIAAMDAIAAFASTSEKELNLLLQHQQLFKRLVQLGGSTKGPVKVNCFHAVARILGVRTRLNVAPEHVPAENASLWALNERLFQAIGQEARRQSTMPLLMDNLRQPFDEIRNAVYTLLRAVAAQNNEWGLRALLSYGGFFEFLLDRTTEPTKETREWKFAVVDAVLASPFQTLLDATVLLQLQEHLRQGPYVGKSVTELEMEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJC4</accession>
    <name>A0A8K1CJC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014698</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJC4"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="585" mass="64070" checksum="C3D751AD4E32F578" modified="2022-08-03" version="1">MENSRRPHTRSSAERAAQGGILLFDPEQHEHLDRQRFNSVQYQTTSFNSGGQTSITSDERSRPTVQAYEPRTNFKQNADAAYVRESYDHTNPLESEDVDTISREVRPVGASSGVQISVLYIMIGIALGVILGVVLYVVKASPLVAQWVALPGELFLRALKCLVLPYVFCAVAVAIGDIVYVGKVSVVGFQTVRIFITFWVATAAMGMGVALLFRHQFHMNNAQASTKHNVGFMCKNQRVMEMRESGTVACSGYNSTSATTFQIVDVNNIFQKGAEKATTTMGVSEVIRTSLESFVANNIISSFTNSYIPSIVTFAMLLGTIAGRNFFNKTRRVNYLYLVMLQLRNAFFLALEWVIWLTPVAVISLLAGAFAKNQASLAKFTDMYLFLIAILVAAVIQVGILFPFIVFILTRCNPYKHMIPMARAYLFAFGCSSSLATAPVTLSCIRKAKVCSPSIANFVISLGVCANASASAFYYPITIVFLAESSGLESEITALRLFALFVLSMVACVATPGIPNGALIAMGAFYKGLLSEDALPTTYAFVVAMDLFVDRIRTVCNVNDDVMALKVIAENTDETVSAEYLGQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJG2</accession>
    <name>A0A8K1CJG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJG2"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="78"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="387" mass="44466" checksum="C067AFC915BA91FD" modified="2022-08-03" version="1">MIVLIYSALNLLWILCNSAIINGVQFALFLLVRAFDTAVYRRCMGAVQALWVDVASSCFPTTLLDITGDLPTDNSRPAIIIANHQVDADWWYIWQAARHHKGAGNIKIVLKDQLKRVPIIGWGMRLFEFLFLRRSIDHDAKHIKEYMDSLIHDEFPFWLVIFPEGTTIHTEYVVKANAFAEKTNRPKFEHVVLPRTSGLQIILDAVADVKPDIYDLTIAFPSYSGEVPTFDMGYDRKIDTDVPSMKSLLAGKKPGRVAMHGKKFAYDDAVGNLEKFLDARWTEKDARMAHYIEHKEFPAADGETRRSIKTSSSIVAILRLWIGVTISGFLLPFVVLSFFPLYTVWVIYCFIYSIYDRTTNFWWPYIFNLILERAAKTRDGLEKLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJM2</accession>
    <name>A0A8K1CJM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJM2"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="288"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="372"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="590"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="807"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="892"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="953"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="912"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="991" mass="111818" checksum="311B54313483E0CF" modified="2022-08-03" version="1">MATQHDDSGEPKAFLTEVLTQDATPVLHRPYEQDPEKGFTMDIMMMMDMEKVSSLRKEFQQKDRGLSVAEFIYVMVRFVQSSESTVENSRLRNLSERQLIANLCELFAQIDINGDGSMEWEEFTSFIVDTGLTVKSHQPNAIQHYHHVPWEDASKHSTFIDHIYYFPGNDLVGLIENCSSVLKLYNSNCELTRTIRSPEGFVQCAEHLPKLEQFIVASSDLQFRFYDDTTLRLLKSCHTPTSQTCLKWYPESPTLFSAGVSGTVYAWDADRMEEKHHMGGESRGRVLTRSHDDMVLDLLTLPTLESLASASMDRTIRLWDVHTGKHKQQLDGHTKGVRALAYSSEYRFLVSAGFDFDVLVWNPYVDQLILRLHGHNNSLCGVEIIPDTPQIITADVDGVFKVWDIRNFACMQTFTAEGMGHVNKIVSVTSQKRIVAAGKKLIKFDYEKLENPKLTDDHPVFAALYNPTSLSFITAAGKDVKIWDARLGKLLRVYRGLSPFDLTALCLDSRERKLIVGDHEGDIHVFDYLNGSQMKTFAYPDSDNRAHRSEITRLCYCAEHMAVISVSWDSTIAIHDESESERGVLLRRLTGGHTTDISALSFSYHLSLIASGASDHSLQLWDFEFGRFDGTCIGHVSGILALQFLDPFPLLLASDNMGNLCIWGVRPSRFKGKCVYRFRNQRIPAVGGGITSVNCLAVYRPVSTDDPDAFSSYLVITGDDKGVVAIWDLLPILTKLEEDYNMRRLDRPVECVNPRRNLRVNAESMVRKVKNGPEWAAFQRRDPTSSFFFSAGMPLVTESAPTCLQQWKAHGDIVYSIQMIHEPESLITASFDRHVKVWSLSGECLGVLMQGDMELSRRPWKFAVDYDSRERKKELAAESVIEEVQELLEETEASHLGTAASLRRRRSSNTPRKTEDGDGDRESVLEEIVRAPPSVLPPIVGTKPVHRLSLFAPTQPPTAIRKTPRRQPVSVAAAGRTQILSPRQLRVLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJQ8</accession>
    <name>A0A8K1CJQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJQ8"/>
    <dbReference type="OrthoDB" id="166941at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="602"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="724"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="866"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1034"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1113" mass="123357" checksum="7F370168AF40A3ED" modified="2022-08-03" version="1">MQQAGYRGTSISKVPRSGAGSSSNTILVNLDLFVVRATIGRDISPEDDDLIVLFRRNSKEVTSEPTQWRDDHVAYWNQHVGIQTSLLKNKNAAVDGSEFLRKDYEVVVVALPSHSAVALFSLDFADVVQSQRPGRPKAFRISPTKCRDLAAALELEVSWEYASAAPPTHSPPPTHSPPQPMPLSSGPPLTPTSSSQASSAPIYGGGMRRTGNSIVSTGTAGGSDDACGDCRTLRRRLERKELQITQLEGFLKESQKRIDSLVFENDELIIREQAETKNASKYRMLNLRLLQELEMAFQFCAQQMLQAQEQAKASDSAAPPPLFMFLPQFEFMERVKKFHFELEQLLGGEQTPRPPSLQDPAKIWETFDFRGEMETALERNMRLREQLEFLHRSLLYEMPEGQGEGGNMPLPIKRTVTNTSTNTGSEFSLHDADEPIDNSRGSPVRTITEQLNALERENFMLKAKLESATESLKTLQNPHSISDAAETTSSTSSSHGHGPLGGSGHDESLRFEVEQLQNEKANLLEELQATRSQLLAMQNDRPSQLSSLASDMPAPMPSSSPNHMADLLSSSGISGISSNGGVPPKIEEAAPAGGADFLNQIYMDIGKAKAELEDKVKHLTQELENAEEYNERLVEQLNIMRHEHRQMSIASEAKVISELAVEEHAQQLEILQKEMAQLNMALEDKSGQIRMQQQELQFMHQHLKEKTARVMELEGSQQSGDAELSTVKQALGQAEKRIMQLEIELEGAQHDLFELKKQLQQQQEQQQQVQVQVQQSVAKEKDDSQRDGEVAELSKQLKLARQEVMQLRYRSNNHESMNEKLEEALKEKKTLQVKLTALEGQLYEQRIRTISGTGFGMGGAGNDSTVEQLQEELEQKTAQLELCQRELKMLEHEFAVRNASKAVGAKSAGGDADLAELEAKVTTFAAEIARLCERNDEQAARIDAMDERVAVATQEKDELETILRDMMREMDALKLAPHDEGDSEEEGEMSPDMEELVPVAVTAMHNQPPKEEEKPAAPLRAVDRWQNAVRRNSAPRSPTSGQRSATSSFTTQSSPVSSGAPVPKNKVAHLIKNFSSASPDASAPAKRRSTLSTSPSAARGNSESFRFRQGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJR0</accession>
    <name>A0A8K1CJR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJR0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="16694" checksum="5E75851716EA3165" modified="2022-08-03" version="1">MRRFLRAIGFSCFSRRKERRDTSAALRAITIEDARYTFQQNLLDDDVSTVYSSHYDGNDYLSIQQRQQLQFVLFGGTEHSSSFQPEQIGPRDITVGPIRLSDIRADMNDRQLPVFFTPSPPDSFGISTAKDGFINLGDLSRLQATAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK04</accession>
    <name>A0A8K1CK04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Macrophage erythroblast attacher</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK04"/>
    <dbReference type="OrthoDB" id="1933455at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16659">
        <property type="entry name" value="RING-Ubox_Emp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="8">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="410"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="6">
        <location>
            <begin position="410"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="56662" checksum="6D7F3087039850BA" modified="2022-08-03" version="1">MEELLHPLVKVPFEKANKSFRLFHKHVTREVLGVQKTIQELQAEQPPAQHAVVEETIQRLQAIAERIRSTQKETKKFIGEQHHAVETCVLRTQHSRKQSQRQHEQKSSTSQAVVTSQGAETGEESDVTLEDPTDHDRLIADYLLYHGYMESSKVIQETKGIEFMVDHDVHLECRSILNDLHARNVVTAIEWCVSNASRLRRLQSRLEFQLRLQEFIELVRSDKKLEAIMYAQTNLTPISMQHENEEIKKSMMESIQEAMATLAYKSPDQCGVETYSRLFSNERWQSLKELFRSTFCEVYGFHSPPSLCIALHAGVSTLNTRTCRRTREARAFANASTAGKDGDEVESSRETSGENKRQSDSTSPQRSKKTKVASSQDASPSQRRKLSNSSGSSSNSSHGLVFHDDSVPLCPTCSDVGAKLTVNLPFAHHPHSRLVCRVTQRVMDEHNPPVVLPNGFVYSQQAIDQLMKEETQTESSLPMITCPETLEMYNSSDLKPVFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK26</accession>
    <name>A0A8K1CK26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK26"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000003">
        <property type="entry name" value="Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF52">
        <property type="entry name" value="CATION EFFLUX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="2">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="16739" checksum="772B4D1F517F2C1C" modified="2022-08-03" version="1">MQLVGVSASEEFIDEVKELCNTHNAKLSLDIVRAYYFGSGSKYLVELEVVVPADMTVKDAHDIALQLQFKVENLEDVERVFVHVDYKARDYDEHVVSREEDALLTYAGYSGDETSISCRSSTNVLSPKTVEVVVSSPVANGESSAHFQAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKK0</accession>
    <name>A0A8K1CKK0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_009127</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tweety family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKK0"/>
    <dbReference type="OrthoDB" id="67634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005229">
        <property type="term" value="F:intracellularly calcium-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072320">
        <property type="term" value="F:volume-sensitive chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006990">
        <property type="entry name" value="Tweety"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12424:SF8">
        <property type="entry name" value="PROTEIN TWEETY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12424">
        <property type="entry name" value="TWEETY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04906">
        <property type="entry name" value="Tweety"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0868">Chloride</keyword>
    <keyword evidence="9" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="454" mass="50897" checksum="7731403D0DCC17CA" modified="2022-08-03" version="1">MSTTPVMPLLPPDYHREVARELVEFFHTFYRFGSATNTFNLNDPQYQQFLHNLLFGSLTIGALVFIILCIIVVRRTILHIRSAYARRWAMESNSLEISAVILLTVLAISSLSGLLGEAQVDYSASVVRGAMTNMSHVFTDSQHLAWQSANASADVRFRADSMIVSFNESDLPQQASKLSLESLRMLHAARDLANVTDALLPKNYADVAKEWQFSYFMLKSTTNFAILSVALASFLSISSIGWSMLTPLRVSILIILSVVPISHTLIGVYLSSTIMTADFCAAPMNSTVTLLDSTPVVNYYIECQPNVTNPFKSYVGSLQDTTDVVSTLQKELEDYAKSHGDIGSRMKNDFLDPIGAQIQHIDEFLTTFNKTQSCQPVAASFEHAVDAYCEYGVLGFFSMWVHQIILCLILFISVVTSVLVYERVHIREIRTDIRYQMLSTYDDDNMEHVYLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLJ6</accession>
    <name>A0A8K1CLJ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLJ6"/>
    <dbReference type="OrthoDB" id="101550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="59270" checksum="D3CE9B017BE47FB4" modified="2022-08-03" version="1">MSAAAMNFDHKMCLFKTVNKTWKQQPVPQKPTQDASVSTRRFAKKMQAMENEDSASSTEKNVRWRQMVISQSLAATTVCLLELQDCTDGFRLTTKQLTVLSVLGGLSSSAGGLLLSFTVGYPVPFGAQASAPFLQIVLGIGIFVYKGKFFKETPTARPQLRAALRLFGALSILTLVYTACHTAFIKLSGFVQSVSVLSFPLMKILWKNLMALHCRDLEDEKPKLVVMNIEIFHALFSTYCMQGASSFATTVSIIAADLLHSWLSLRDVNVRVNRILRLEARKNQRKGPQSAHVAPPTDPVLDVPQLSKLSVGARMWRWILQMDARVQSGSIQIQRPPRRPETTASILPSPPPYPSNTHDSPPIEAVQDAHPVRGSATKVRLSPEERGARLQTKKQELLHLTECVLLVEYVEIIIPFIYGVYAYICFHLPVHHFYVHLRNLDEAGLRHAVSNVLVYASMEFLTFVMLNCALGQKLPVKPMYQLAFVLETQWLPVQQKLQFWTLFTILHTLQHFGVDFTLKFQWLHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLZ7</accession>
    <name>A0A8K1CLZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008151</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLZ7"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="26"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="371"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="508" mass="56022" checksum="28AB8DF5E953979A" modified="2022-08-03" version="1">MDVSSTSDNAQPEALDLRHAVTQNEYRVQKQISKGSYGDVFVAERISDGRLVCLKQMDLEFLSTGERNGCLEEVRLLQSLPHHPHIIRLYDAFWDVSIVAIKHRLVLSLEYAAAGDLDVFIQSQPRDVTQTLRIFAQVLTGVGFLHSRHILHRDLKSKNIFCFNDERVVVGDFGTCKPLASTVAMAKTLVGSPLYMSPELLDDEPYSFSTDVWSLGCVLYELLTSRTPFAAPSYPAVVLKITKAAYDPLPPSIPGDVQGLVAKMLQRDPHERPSIAEILDMEIVKQHCQDVRAVNAEPREDVESVSSEEEPPPEYQETEEAVDCIDPSRVAEESFEDCGQPSGEKDTAHFLLPPPAPVTTTKALTHAELVHDSSGLPLPPPPAPQSRKPNSTSSTAAVYPTDRARLASILSRERLQMHRQHKTQAASSDDTSRYLSCIPHLDADRVPSNAGTRVVKKKPTPRTASSPPQAQRIRPRASLPETNMMIVGTKVRAVVDGSKVSSRAPGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMD0</accession>
    <name>A0A8K1CMD0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent 3-hydroxy acid dehydrogenase YdfG</fullName>
            <ecNumber evidence="4">1.1.1.298</ecNumber>
            <ecNumber evidence="5">1.1.1.381</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">L-allo-threonine dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Malonic semialdehyde reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003924</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L-allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimidine degradation since both are able to detoxify malonic semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26438"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16510"/>
            <dbReference type="ChEBI" id="CHEBI:33190"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.298"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-allo-threonine + NADP(+) = aminoacetone + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:43524"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58320"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58585"/>
            <dbReference type="EC" id="1.1.1.381"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.298" evidence="4"/>
    <dbReference type="EC" id="1.1.1.381" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMD0"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035527">
        <property type="term" value="F:3-hydroxypropionate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086:SF3">
        <property type="entry name" value="NADP-DEPENDENT 3-HYDROXY ACID DEHYDROGENASE YDFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086">
        <property type="entry name" value="VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="12">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW66159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="255" mass="26555" checksum="8ED43207C7CAAE43" modified="2022-08-03" version="1">MSELSGKVVVITGASGGIGAAIATRLAVGGASVALGARRQSALEEVRDAIAQKVGTADRVLIKETDVTKREDLHALVAAAVAQFGPVDILVNNAGVMPFELLSNVNQDSWDKTVDINCKGVLNGIAAVLPAMLERKSGHIVNISSDAGRKVFPGLGVYSASKMFVEAVSQALRLENVGSGLRVTTVQPGNVATSLVENGQSSSGGDKEAMERYGGASGYEILRPEDIGNAVFYAVTQPPFVAVNEVLIEPRDEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMD3</accession>
    <name>A0A8K1CMD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMD3"/>
    <dbReference type="OrthoDB" id="160483at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="563" mass="63106" checksum="E1B74328313E4323" modified="2022-08-03" version="1">MIADAVARLQDTLGAVITEKQGAMLAALVQTVMMHLATPTNMLHGVTDTVLTNQKIIKQQILERVANDHRTVLHDVMSQAIAQQPSTVEQVINNAFKNQGGLVNWIQDDQDRQDALMVLSEMKKYVVNMRGNDCRSQFERLLPIYMRALGMTSFPEECSARVMALQGFLLPGNQSDSDSRMDRPSKVQRYRIIWACHGIRNVGNDRSHFSGDLTYDEQMEICASITALGRSLAPVAHSLRQAQFSEMAAIAVSASVPSISPLPPTPPSLLTSKSSNGLDSHSESVAALFRASSLPNVTTSPPANTNRVASPPWSQSSSASPSVPSSSPPLPPSPPSDPVPPPPAVMVPRRNFKFFYNRPSELPEWPAQNKMMLARMLNHMKIVPGANLCEYSSKTSCRIPNCSKSHSYLEVMRYNPLFKLLKCGKFEHFWENDVKEQACVCAHVDTQVDIEWMSTHKTKLCHHGSKCTMRRCLKSHSFEEMCWYNPRYKTTPCEYQNRCLHGELCNYYHYENGPQQDKRDVRTEDDYVGKPIKMLFIERTHTDVANALEALRRQASSPKTLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMP8</accession>
    <name>A0A8K1CMP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMP8"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44316" checksum="58B1D89A0A706168" modified="2022-08-03" version="1">MASIDRSALFTAAAHGDLATVRSFFCQSHVQTLVGETNELLRTTYAAALASGRNPFSASINDMREPWYCRPRPRWTPNDNVELLVEEPVKRRHVYIVDWFFDEEASALVGETIRHLLRPIFKCVRFAPAYGPELAEIILSSSLYRAMSSLEQDFVLSMMLDVAVEANSVDCVRLVVALGVSLANPTNALETSCQHDDDTMTQLLLDCGVSPEKLESNYLIEAAVHGNMELVQLILAQGFADVNARDFHGRTPLMSVFHEWNVYSREDGIRRSYVVSYLLENGADVHLRSSVADSVGVPLPESFFEDEIQEVLRTLLTYGADPNAQDQEWLQTPLQYLADCFEHGPSWTPFGILLSHGADPHLPDADGDTPLSILMATSQGHEHVDKHEGYFRRWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMW1</accession>
    <name>A0A8K1CMW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="10">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_008203</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11 14 15">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMW1"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000002">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 10 11" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="18">
        <location>
            <begin position="116"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="17">
        <location>
            <begin position="761"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="705"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12 14">
        <location>
            <position position="851"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12 14">
        <location>
            <position position="894"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <begin position="487"/>
            <end position="494"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW65561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="950" mass="105380" checksum="2A4B0FD4C5482AF1" modified="2022-08-03" version="1">MATVGVLRRLSYASRRAQLTSTTSFNGLPLAQPRFSAITASAAPQWRSSLVTTSRLFSSEAGDDNPQDGADASATTKKKTTRRRKSAVDAEADVEVVETSVARLGEGDNAPNYPHVLAIPGHRRPFFPGVVLPMTITNPDVTKALLALKESGQQYVGVFLKKPTSGTQAPSTIIDPSKQGTEDLIKDLSEIHHVGSFARIDNMLPFDANSVQVLMVSQRRIVIDGVHDMGPPLRVSINPLENPDFDPKSKLIRAYSNEIVATLREIVKMNPLFKEHMQYFSQRIDIHNPYKLADFAASVTTADGEELQQVMEEMNCELRLKKALELITKELELSKVQQVIKEQVEEKVSKNQRQYLLMEQLKAIKKELGMEKDDKDAMITKYRERLDAFEPGSIPANVLEVVEEELNKMSMLEKNSSEFNVTRNYLDWLTQLPWGKSTEENFDLKKAKQILDEDHYGLSDIKERILEFVAVSKLKGGVQGKILCFVGPPGVGKTSIGQSIARSLNREFYRFSVGGLSDVAEIKGHRRTYVGAMPGKVIQCLKSTQSSNPLILIDEIDKLGRGYQGDPASALLELLDPGQHGAFMDHYMDVPVDLSRVLFICTANVTDTIPGPLLDRMEVLRLSGYDAPEKLAIAKEYLVPKIIERTGLGKDSKMNTPESLGLTDDAILTLVKQYCRESGVRNLEKHVERIFRKIALEVVQDIESAETVAEGDENKEESTEPVEAVEQPATEADADRFLITPDKLFKYVGKPVFQSDRMYDKLVPGVVMGLAWTAMGGSSLYIETTQVMAKGERSGLLTTGQMGSVMEESTKIAYTYARHKIQKLLPENKFFDNAEIHLHVPEGATPKDGPSAGCTMVTALLSLAMDKTVKPNLAMTGELSLVGKVLPVGGIKEKTIAAKRAGVKTLILPLGNQRDFEELDEYLRQDLDVHFADYYDDVFKVAFEQDESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNC7</accession>
    <name>A0A8K1CNC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNC7"/>
    <dbReference type="OrthoDB" id="161167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="71361" checksum="6BF5F3C95296E4C7" modified="2022-08-03" version="1" fragment="single">MKFPLESDPFPPVEATPERVADLENLAHILLNETIAEWEHFVHVQNREVDKKRWKPTKTRESMTVYKDMYHAKSDPVPVYPGTPSTVGSDESNRGLRLLGVGSIVGNLEDFMLGNATISAEQMRIRTSYTDDECVDHRVLDVWRQPTVEDPFTLHSLRWYVKAVPGANAIVKPRDLLLIDCQGILETTKGDRLGYLLLHTVEVPECREIPGIIRCQLSACYIFRPNGPNSVEVYLRSMVEPGGKIIDSVATISSTNALISTWKLPWVGQNRKLTWMMTQPTSVRAEKLGKKVAATKPARKDKCSLCTKSITLLRRVSACELCLDSVCSRCLTVRKLSYIRRNGDLVQVPTAFCKNCIMWSTSMKFPLECDPFPPIEASPERVAELENLAHILVNETIVEWEHFVHVQNRQVDRKRWKPTKTRENTTVYKDMHHAKSDPVPEYPGTPSTVGSDAANRGLRLLSVGTMVGNLEDFMLGTTTTSTDQMRIRRSYNDDECVDYRVLHVWRQPTVEEPFLVHSLRWYVKAVPGANAIVKPRDLVLLDCVGIHEMANGERLGYLILHSVDVPECREIPGIIRCQLSACYIFRPNGPNSVEVYLRSMVEPGGKIIDSVATISSTNALISTWKLPWVGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP26</accession>
    <name>A0A8K1CP26_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP26"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14201" checksum="A889B39AF8E7D2A4" modified="2022-08-03" version="1">MKEWKREKLRQQRGVASENVNASVGQKRAFESPGDSDYDDYDDDDGNFVDTASVPSKRKANEKAPMKKKRWTEPTVKAKMRGTRHIDINVANRKSSAPSSRKKMCLPSGSQDGRPNGRPNGGSSLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP44</accession>
    <name>A0A8K1CP44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP44"/>
    <dbReference type="OrthoDB" id="10256467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="637"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="548"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="689" mass="80004" checksum="7932A4A542AB8BB7" modified="2022-08-03" version="1">MSSHFHDMELRDPTREELYNGPKREKLPVEIQQLSNEDTACTFCGVSYFVFSEVQELQATVKKYKKTFHEFIRFMERERKISQELKTEVATLMKHFNQSATTFSSHAIQLANETTRLRQRDGEMTKQLQVSRDELSRSQNEYSQLQTQFRRAEDDWKLASTLTEQKLRNETLHLSSQIEKCKLQSSTQEAELTAELECERAKIHEMEVVLANARASMSSMERQIITERDQLKQQLLSATERVELERETAKQLEVQLRAVQQELMRIVTASESDRQTTMQLQTEIASLKQQLQSCEKQNAALRTERDEAHAESGLSNDLIRSLRAQIATLEKKIQENLAAMEKLKQEYAKDLEKMRLEHGATVNRLQRDHQKALDDLQTQQKTYLEYLQKQTSDMQQGTDATQHALLEMERKWTEAERQLIHWKSEAERHKGELQDLRSMQVQHKTSIATLERKMVVLEEEKRDLEEEAALLQRQLDQSEAKTKVKLEQMRTELKARCQQLEDHNQQLQRRVDTTQRKYDQLERSYEQLKQAKTAEGGEPQVAWVDGRNSPSSSTKVSNSSNPNRSCHSLPPSNNNQENHELEKAVESLRQTLAQKDKEIALLQQTVHRECLERTSLLERMRSGKILPDLGPAAVLPSSSEAFADRRSTSGKESVAHSDENDEDRGDQPKASFYERLRRTGQRKSKPRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP49</accession>
    <name>A0A8K1CP49_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP49"/>
    <dbReference type="OrthoDB" id="164186at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035432830" description="TRP C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="718"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="795" mass="84015" checksum="46906BF16CF6E6D3" modified="2022-08-03" version="1">MRNMRPFLLNVAVVAAVISSPVRAATDGSSDGGLVITLPPVSIAPITLPPLLTPKPTSAAPKPTSAAPKPTSAAPTPTTATPTPSETSPPETSAPETTSPPTWTPGPFPTPTWTPWTPVPTATPPPGPVPTSTPEPTHTETPRPTEPTPPPPTDEPTPSPTPPTKTPSPTSTPTPTPTSTDDGPDSPSPPTKTPSPTPTEEPSPSPPTKVRPTPTPPSPTSEAPSSPAPVSKNDGKKDDDSDDTESPAPPGASPSTPAESPTAPSPSTTPKPVDNIEVTASPDVTVVLPVGTVAATTTEPPRRYVRGDDVVADTNAPGNYESGTLIMGGSPAVVLGGAKAASNGAGTNSKDEADVFEFLRNFASVCAIMSLLLLLAFHGAALDKRLTTAWALGSPNMWETMVYIGYIQSMASLGHLVLHKVPYFLWKYTDAFSWTVGVPLHGSAPAIGPRRLLEVVFLDGVVAFADRIGINESGLLSKVVGGILLIVGFMLVALVTVVVAVRLRTKKQREFNPAASMNTVQRNRLPMHMMGGVGVLVWLFALYPVSLASAYEITMQVKSGKIASGSLTMALLLFVLICVGGLALAITAISMMSSAHELHETKNMAIWGSVLGEVRYERRLFFVGFAAVQIASGVIVAAVQGSYAQLVLLLILHIGYVVAAWRLNPFTKRSIAMAFTYCFSLIKIVNLIVAFSFVRTEADEALTNEEYAKSTAGTPGRMARVFVILNSIIIIFWFARHFGMLCRMLSSMWATRAAADKLDKVEKDEYLTTTTMSVVTYVSLPGEEESQRVMTRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP77</accession>
    <name>A0A8K1CP77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_004263</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP77"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="14">
        <location>
            <begin position="63"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW66498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="40760" checksum="12F9FE2991408B19" modified="2022-08-03" version="1">MMMESHKMRFLDLQGRRLSTNTRAISAQKASTDNNRTEDVCCSKCTKAGMEWDKYKPSPVVKDYAAVSTQNSKFRKYMEDECVALPKYQVFHGDPALNCFFGVYDGHGGGFCSKYAASNFHHRLAAVLNGKVGTSRQRESELSNQSAPTSSSSTELSDAENNQVLSGEDIENGYAEAFAALDQELEEFDEASNSGSTAVTCLIRKSKDRTTFHVANVGDSRAILYSGGVTTRLSVDHKATNEDEAKRIRDNNGIIFNKRVGGIISVTRALGQIDEKEFIIAQPYTTSHEVRDGDAFLVLASDGISDVFKDEELTEYVLTRLNRGEKAITICKRLLDEAKNLGAMDNMTVVLICLSGDPPQRHRHDEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPI5</accession>
    <name>A0A8K1CPI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIF4G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012236</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPI5"/>
    <dbReference type="OrthoDB" id="27832at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="54"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="481"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="4">
        <location>
            <begin position="689"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="457"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="985"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1010"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1079"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1269" mass="142021" checksum="166701EEC718A28B" modified="2022-08-03" version="1">MADDAPDPQLRAQMEELHKQTQMRMALRRSNSVEAVEQLRADIATGVVKLKSDIKKSSAFGKKLRMLTEHNADVLAKDTKELNLTRYVTECVASIAEAPLKMADLPAAVRVISLLHQRYAEFSTLLVDALTTAFDGSYGTEDKHKLVKRRILLRLLSELYLAGVFHDVQVIATIVQRVVRREGGPAGKSKSKGNMSLAGSSSSSAQLEVPLLVSFAKSVGAEFLGVLPKKYKEITAAFGDEFAPVVRFQQGLVPQSVQNQCLACFQEAYDLICKYYLTQHGALVKLRKRNDREEINRGEISEQHVQELENAKLLFEKLQTSVNALADALDKDVPALPVEKTDDELLGSGISLWEGGEGGARSELRADSPFDDEDTRSFYEDLPDLLELVPAVVLGLTEADVAELKKKKEAEASGEAAAEEEAEAEAEGDDDDAEADGDDAGDADAEGPELREDAEPTPESTEESATTTSTDTGKAASGGYHHQLDSFFTSLEDMVNRDRCDKAAVEFCYKNSKPNRNRLVKTLYSVPRTHLELLAYYARLIATLQRVFKDDIAGELVDLLVSEFNYLIKKRNQFRLESKVKNIRFIAELIKFKVCPPAVAFRCLKRCFADFQGHNVHVATALLENCGRFLYCSKTTHVRTENFLGIMMKLKSAKHLDPQAETLVENAYYMCKPPERVERAVKQYDPMYLFVLKLLYEDLNDSTMSRIIKTLRKLPWNDSATTDMVVKAVLKVTKGRVMQMRSVCQVVKRLARYHEEFSIVLVDDVLESIRHGLELNDYRDHQVSLGNVKLLGELFSVGLVSMSVIFDTLYLLINHSHDLWTLPQYSAPQATAAPTSTDQGAASAPLTATQIEEFKRRCRLVPDLRFDPRVPSEVDSPSDVFRIRMVCALVEACNLRVSGASGASNADRGVSKTRLGRFMTFFQRYILSKSEIPLETDFVVLDLFDALASSLKDHFRRFEEWDDADNAVTEILRQELEVAERKLAKQNSTTAATTGVSADGQRRTSMDETGALDDEYDEYGEEDDDSDEDDDDEDDDEEEDDEDEARGEEGDDDEDDDDDGDDDDDEEEEEEDEEEEEQLIIHDRVQKTEEDEDFEKAFKAMMSNTSEPRKLLGRVGVDKMAIPTMIKSSTQPPPALAMMTSNPSDNPNGVVFRMLRRGNKGKVEARHLLVPQDTSLAQHSFRQEHAGKQQMSELKRLVLQNVEREDFLISPNTGVEMLSTAPTSSSARPAIQQTHRVQSEVHRAGYGANAEWNNAEFGLRRGKGYRGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPL6</accession>
    <name>A0A8K1CPL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPL6"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="1">
        <location>
            <begin position="162"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="393" mass="44895" checksum="480A4681D9A3AF57" modified="2022-08-03" version="1">MTMDATRPLLAGDKEDFVEQTNGHYTNGTHHTSVALLLDDDDTHTSTCCTSCWRVLCCGRRSSSPSSGYKELSSRRDRLLSNGTASSTGSSNGYPRSYCGTGAYETPRDDDDESLCGAWACWKWIFPDRITDYEDFVGSETLGEIYFIRQKTREFFEPANAEDNEMVHNLWNALFPTLPYDGRVNPRWRDIGFQNDDPASDFRASGRFALKMLLYFSEHMNDEFKRLVRENRFPVCLCALNVVEMMLIHLNLKDPLPMVCPCCGTENAELETSHPSRDRPELQGFVSILADCTWSSASNQFNYAAEWPVEVAFAQVFMHAMIVLDSVWRQMLQRDPTTTLMHFREALLETRQKTLAFLARRNTPVNLVELQAWSTRQLAAIQRQPKHSSRTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQA2</accession>
    <name>A0A8K1CQA2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014067</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQA2"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14479">
        <property type="entry name" value="SPX-MFS_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045264">
        <property type="entry name" value="SPXM_SPX_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF64">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="659"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="2"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="498"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="76067" checksum="13552824A1ADACA9" modified="2022-08-03" version="1">MVQFAKKLVAAQRPEWSGHYLEYKQLKKKLKAVQASSRDLLGPSTPGAAQDGFQRALDAQVERVVLFFLTKQGEFAKTLAALRREQDETTTADLEAMHALGDRFRRTGDELVQLLHYVELNATGIRKILKKHDKMMKERKIMGAYLSSRTDSQASHLQQLYHDEGISAIIATIRTALSELRALEAQVDASVSHRLTRTISEDEPVLSKIALARRRLRQSTQYVQTIAAKALIFDGESSEDEEDDSSAYVSFLRSRSRSSYASRFLNMSCTFLYMTNYYIVAPTSGDYAAALGAEAALSGVIVGMTPIASLLSAVLYSWWANRSYKSPLLFATVCLVIGNLLYGLALYYNSIAMAITGRLLNGFGGARAINRRYIADNYSREERTQASAQFVTASALGMAAGPALAAALDYAPDFSLLGVQVTVETAPGWVMFVFWLIYLLAIALFFEEPDRSIPLSDPRRSTYALENGEQMPLLTSRSRTVSTQPPPKLSSLWRNVPVVATLVIYIVLKAVLECLLTASSPVAQYYFQWNSTASGVYLAALGLLMFPTNLLVSWYCDRYDDRELILRSEVLMLLGVAVIIHYGTGAYESWQFIVGGIIIFISTNVLEGVNMSLLSKTIPKAFARGTFNSGLLATEAGTFGRALGDVLITLVGLPGIQYVLNWTFAPMLVISALTILYTLRVYSSLATTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQF9</accession>
    <name>A0A8K1CQF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl endopeptidase</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Pro-|-Xaa &gt;&gt; Ala-|-Xaa in oligopeptides.</text>
            <dbReference type="EC" id="3.4.21.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQF9"/>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000005">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="9">
        <location>
            <begin position="66"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="8">
        <location>
            <begin position="517"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="749" mass="85736" checksum="D96FE58B38FD1AD3" modified="2022-08-03" version="1">MSKVSAQVGVAVVTAAAMGMVRLRRAVYSTAKAIRPPVLEKRPHMVPFGAVPGQNRGDNPMKPILYIEDPYFYVRDDTRKNEEVIEHLRKENAYTEHKTKHLTNVRENLYNELLSHVQETDEEYPYPHGDYLYYTRTEKGSSYTFHCRKAKTGEESTSTAPEELILDENEIAKGQNHCDVSNVRPSPDHRYLAYMVDFNGYETYTGFIKDLKTGKLLPDRLENISSLQWGADSSEIFYATQDEAHRQNKLWRHKVGSSEPNECLYTENDEIFSAYFGKSRSGNYMFFMSSSSETSEVSFLDLKNPSKGLQLIAKRQKGVQYWVDHHGGHFYIVTNKGKAVNFKLVRAPVATPGVEHWQDVFPYDSKVKVDQVDCFEDFIVMNGRQDGFTQLWVIKEKASGHFQKYRIAFSESSYTVSGSVNRNYDAKKYRFSYSSMTTPRTTYDYDIDSKEMTLLKEKPCPNYDRTLYHSERLEATAPDGTKVPISIVYRKDLRTKDRQPLHLYGYGSYEISIDPSFVSTILPLLDRGVVYAIAHIRGGGEMGRTWYESAKYKTKIHTFSDFIACAEHVIKEGITSPSMMTCEGRSAGGLLMGAVLNMRPDLFKAAIAGVPFVDVMNTMSDATIPLTTGEWEEWGNPNESEYFQYMLSYSPYENVKAQAYPTILVTSGLFDPRVAYWEPTKWVAKLRDTKSDQNDVLLKMDLSSGHFSASDRYHYLREKAFDLSFLLDQLDRVREADKKKPAPKAEQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR42</accession>
    <name>A0A8K1CR42_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007677</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR42"/>
    <dbReference type="OrthoDB" id="148732at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04371">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000465">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DEP" evidence="10">
        <location>
            <begin position="211"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="376"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="644"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="714" mass="80554" checksum="C85BFCE0D520859E" modified="2022-08-03" version="1">MHSSSGSSSRRTSSNARPASSSTSEQRLKIKTKRRYMLKVTPIEARDLLLAENGRVRNVYCTLVLLDADMREIKGEKQRTPPLRQANPVWSPLKAAVLKSMQSSVESHQPLGIGAAAAQEEYTFGIQTNLMHAKYLLVKCKDKGRVDTDDLGRLLLSIEDLNTSGEERVAWYDLQIRPGGKMKRVQGKIRISSRIVREPSLWQLWSCAEQMRREVPSKDRSLYLKPHPCVITGKEATDWMLCHGPNRPMAGGISCSTEEEAILLGSCMLRARIMRHVSGDPRFLSSTRMYYRFAMHHLDQAKQRDISRQMNMILSGEAEEVDDDESEDVGTNSASTPEEGGWDPSSSGIGNTMAAPPPPASSNRGKSRSTLKIEDFELLKVLGTGSFGRVVSARARDGKVYAIKIISKIGMDENQRRNAKIERDMLRDIHHPFVASLLFAFQNEDKVYMGMEFFNGGDLRHHLNLNTSGELRLTPGRIQLYAAELVAGLAHLHSLDIIYRDLKPENVLIAKDGHVVLVDFGLSTYSRKKEGDKAHSLAGSPEYIAPEVLAAADDKGSSVEYDRSCDWWSLGILIFEMFTGRTPFKDENKAIMYRNIKEGHLYVPPELSEDAQSLLTGLIQREPSERLGSNEAVPFAIMNHPFFSGIDWEALQQKKIEPEWLPDVVDDADVKYVDNEFINQVPVDTPEWRMLDSVDREREYFEDFTFRATRVMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRK3</accession>
    <name>A0A8K1CRK3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRK3"/>
    <dbReference type="OrthoDB" id="167143at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="465" mass="53573" checksum="9AAEAC29E1D61D96" modified="2022-08-03" version="1">MAHAVMAPPVATDASFAEDDDDGVTDSRRNWGPEVTLKLVKIWKRVSEEHPDIGRLERMEMIYDEFQQSLDCANRSRKAVEDKLYTIKQMYHFIIKMNGNFKQGYRKSMPTWFELTKDERRAVRSLHRIRIPNISLEVFNVVDSVLNPYPQLLQPNENISTHMEVNQIISNLRQEEKNGDPQETSPVVSISETENGSSKDSENVEVLDNRRNWSYEVTIQLAKAWHTAVRSNRELRGAMLSQRVYNEFMSLVGGCSRSRKAIEDKMHSMKEMYRFIRTYNAECLPGSQKRPWFELTKGEKRHLRTTHNIRVPNLSVDVFNELDAFMNFGSDLLDASSTALLQVAQHYQSDHTSFASSGLTIDSTNKQQMAEMLMNRRLPGRTISDHIDTEPTRASQIRRLDPNEAGESPPSKRCRVDQEAGTIELLLQQLVALQQQAIVERRQQHQEQMHLLQAIVQRLPNPPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRX1</accession>
    <name>A0A8K1CRX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005922</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRX1"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="182"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="404" mass="44939" checksum="D2A5A5C530AE5F9E" modified="2022-08-03" version="1">MSHRRVGAPQRYAGDQNSLHRCAIALCSNPAIAEGLCEVHGRRPGDMPVNRTGGYMPNGAQYMPQGAPGYGNETPDRYRSSPNVAMQPQARATKKQKPNPEAGRHPMMGMPSMGGSRPMGKNYPSLTQESLNQMVSHGKYSKGPTSMSTYDDSPYLQGHRPAQSSTTGSVLSDSESNGEGGDRETNLRRERNRIAARKSRQRKLDRISNLEEEKMRLEQHRDMLVQEIRSLEKKDSNVSSNTVMTITDKEYAQLQSARINIIKAVEEAYNSGDIFATMQYLRDDSIVSGPQNSSVHLRGKDALVLDYLCTTYLFSDIDHQHVKVDSGGPRSQHFRVHWVFSGIVKSAGVSMNKEFLELIESVKGKRVQIEGVSNFSFSGDKIVYVHRTADQAKFLSALVNLSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS60</accession>
    <name>A0A8K1CS60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">GPI transamidase component PIG-S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001028</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS60"/>
    <dbReference type="OrthoDB" id="28748at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019540">
        <property type="entry name" value="PtdIno-glycan_biosynth_class_S"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072:SF13">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10510">
        <property type="entry name" value="PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478753" description="GPI transamidase component PIG-S" evidence="11">
        <location>
            <begin position="24"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59569" checksum="403D0585A2D9691C" modified="2022-08-03" version="1">MAGTKLQIVSGFVLFALLVAPFAYQLTQVERVELPASRIHALSWENSRFATPSRHVVQLWLVDSAADAASDVRSASSRIQYQVNKLSLSAADREALRGAASADQVDETLLRVLPTTNDFSVVFLCDPTALKDAQDDALAVVGKHRHAFSRACSPSDKAVFAAIEHLVQTHVFPKERPPTERDTRRARVAVRYRLQFTLLKEHADQAWTWDFEALQQRYLAPVLEKLHSIADFSVEHQVVHFARLAKDIHRNAEGNYSYINADDLKGFKSANDYLTSAVLADREQVLHFMAALPDAAHTPLRIKTNNNQNLASSFEIPGWGTVVVLDPSHLDSQFAHEELQRTVGLFISQLRTLLGLPSFFHRSRDNTNKHLTFLPSPRNGIAQWELDHVHETLLRRHVRTTIETLQSIVRLVSDMTQMTVLERVERRISTALALVEEVLCVNQAASHECASSFGADETATLLRKAGEAADNADAAYYDHTMIRQLYFPQEQMLGVFAPLLAPLLLPFVMGWIREFKRVRSKQKDKAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS71</accession>
    <name>A0A8K1CS71_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS71"/>
    <dbReference type="OrthoDB" id="156912at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="30086" checksum="17235D9A815A7004" modified="2022-08-03" version="1">MLVPRSLHWGHGYVVMFLAMAANLVLDAYWRAVDVCELFPQFDFPQTFQEEILLHHTRLPLVRWPVSTVLVLGVLLVLYIAAQLRLIELAWLFLIDVLSGRWLYNLFFVQLPAWLPFLASDPGVPDLLSDVDDDDIDDLEWLDNNAQYELDDEAMPALHDDVATCSHQAMEKLVQVKLEHANRVIKRPDDWLVFDPERETLVLQKELQTSPATATEDELSDVQSTTSTSKTQGADESSERDGDEDEVRPEDDDDKIEDRQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSY1</accession>
    <name>A0A8K1CSY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSY1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470826" description="Elicitin-like protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="70814" checksum="8EA9455E53A15FD3" modified="2022-08-03" version="1">MKISLVAAISALWTILDAFGSVNATECSTADLDTLKSVRDDTLKGICASSFAAGPPPANSAVPPFCGNEDCLSTLKSAVNDLPDCEINGLSIVASVKMMIIMCSSDGIPPPMPPGAANGSFPMPLPPPRPGNGPLLAWLAAAGDTNDSSVSHASRVPESHDDLLDLSFPYLLHSLTMKLHHLFLGTAMALSAAAAKDPACTDKQDDVIEALPLSTEFEKACGKHELNQFGAIATFFDVPMCKFPDCVDFLLTSLPNCTRNGVDFRGVIRRDGERCAKAKEDPEWGALWGLTSSSGSTEEEEVTLRPSGADTTDSDWSSHSTTVATECTFKQQSEIRNLGNDEGLQQVCDVGSKKTFTDVSDAPLCSSQQCFDYAKNTLVNKIPDCTISGISIKTAFKLALAMCEEAGIGNSAASVSNIGVAALMSAIVAAVVVIAPPADVAISKELFVGMQLLVAFLGLSAVAQASECSPKDIKTVDTLGSSAQLTAVCGNDVGQLFADETASLPLCDKPACIEGFRGLIHALPECTINGLELNKVVEATIRFCENEANATSSSSTDGSDSDADFDDVGANECTETEQATILTLQKDRERAKACGTVDTTTTLEDMDDLSLCHADCLAFSETKLLPALPDCSVQGVNVKTAVKMAIAMCEVVSDAPGSSVVASVTALVGFAVAAVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTD4</accession>
    <name>A0A8K1CTD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTD4"/>
    <dbReference type="OrthoDB" id="2504340at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11371">
        <property type="entry name" value="RNase_PH_MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF2">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT MTR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="9">
        <location>
            <begin position="43"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="10">
        <location>
            <begin position="176"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="28126" checksum="B2908B4F4B5019D0" modified="2022-08-03" version="1">MQNCYFPAIAKPRGGGDAQSKQDDQVMIDKTLRLDRIRASADEMRPAFMRLGVVSGAAGSAYVEFNRTRVVCSVYGPRNDTRSRREFSQEGQLVCDFKYAPFADSTGRRERGQDDDELEMSSILTQALSPAVMLAKLPKCVVSIYVVVLESDGSDLAAAINCASLALIDAAVEMYDIVTAASAGIVDSQIVLDPCHEEEVHGEGNVVMAYMPSVGQLTHMVQSGKIQHGQLQEAVDLCTDACSGVMKHLLTTAITQAVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTQ2</accession>
    <name>A0A8K1CTQ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTQ2"/>
    <dbReference type="OrthoDB" id="155775at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538:SF1">
        <property type="entry name" value="VWFD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="598" mass="65086" checksum="07DE2065747E097C" modified="2022-08-03" version="1">MTKPETQRWSTRKAVGVAAVAAAGVCAGAFGLFARHADHFQHNATRLLTAMAEADAIEITLTPREGSTLAPGDMQMRAIVVPRGSEGDFDGRLSYVNVDRQYNFTLVDGRGYVTVENAETGKLINADCLYPRNIPPIHTLYDVLADARVIDPEDADDEFTIMCDSGKAVEFMFAGEPFIFCTKDDTAEEDVKTIRGRDLTATLNFLRDNSDKVESGVSLAAPSYIDISKCEVLDSDDDDDDDDNNDEEDNQTRSLRALMASHYSAVSTRVKDAVSVVTGQPRRSLAATQEADCTCRDGKKPCLFVHGLGKGLFGNDTGIYNEFDEYWPDMDKNAKCCSSVKFVRMDTMRNAWFDDVLAKQVCDAAVELTNSTDKMALQNIALVAHSMGNLIISNAAMKGFCAIDPATSKWISLTAPMLGSQAANLAIDICGREDDVNSDSATEATTMNVTVAPAANPLVGAMELVGLCPMVRAVSKLAFYRSKYSNATEDKLWEAAVEYSRDTVTSQLCGVSPLGLSSIYSVSFGTVGAAAKHASKENDGVVDFASCAAGREESEFGTHWKTSTFYKARLNHADGHFKSGDGWWGDDRKPLKWFNCQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU39</accession>
    <name>A0A8K1CU39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU39"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000286">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="24"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="175" mass="20399" checksum="9204DD8E85300303" modified="2022-08-03" version="1">MLHFSHKRQRTTTMTDNNQPQTTKVPKFIRALYTIFAHEDPAILAWSNDGTYFQIHNINRLEQQVLPRYFKHNKFANFQRQLNNHGFRKWTKTRASVCTFSHDVLIQCELSELPTMLSENGSMPVSGKRIRLNSESSESSEDEDNQLPMVKDLLEEFEPPNWLTTCPSQPTTKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVI3</accession>
    <name>A0A8K1CVI3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Polyprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_001542</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVI3"/>
    <dbReference type="OrthoDB" id="112217at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039537">
        <property type="entry name" value="Retrotran_Ty1/copia-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057670">
        <property type="entry name" value="SH3_retrovirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648">
        <property type="entry name" value="TRANSPOSASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648:SF11">
        <property type="entry name" value="TRANSPOSON TY4-P GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25597">
        <property type="entry name" value="SH3_retrovirus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="14" id="KW-0917">Virion maturation</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="18">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="19">
        <location>
            <begin position="422"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="183"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="689"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="792"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="695"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW69386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="91927" checksum="5728C3B44206D2C1" modified="2022-08-03" version="1">MKRPEDLLGSDNYFHWEFNMRMMLARKGLLDHVLAVKPEQKWTEDWRVKDMKAFAIVAQGIHVEHQSKIRSATTAKEAWDLLREYYNRSNLQNRIALTRKLHEFRMEEGSDMANHLDRFGELVVAMEAVGDALDESRQLVILLGSLPQEYETIVTVIENTKGLTLDEVKEKLLKQYAKMQEQEPAEGAFKARHRGGRRTKTHQRRGGSERDKGQYGDSRPRNGRRPSQVTCFSCGKVGHKQDRCFKKRGGDDETLFMARAASAVGMQHGWLIDSGASCHMTPSRDDFCEYENLTKPIVVTIADGKAMDAVGRACVRVICQNGRAVKICDVLHVPALDRRLLSVPKLAGRGLVTRFEAKWCSIQKDDEVIVRARRDKNVFVLRVREESAMLVEFKDDQSKWETWHARSGHPNIETYKGIQTVTTGLPELTKSSEQLCGGCAMGKLTVAPFPHASTTKTNRVLELVHTDLIGPMKVKSAGGARYVLTFVDDFSRHVEVYFLKSKSQVTAKFVEYIREMENLCAVCAANGIAHQTTVPYSPQQNGIAERMNRTLVEKARALLHYKAVPLVWWAEAIATAAYLINRMMSMSKPGTTPHEICFRIKPDMTHLRVFGSMGYAHVDASKRTKLDPKSFKCRFLGYAENSKGYKVLNEETGKVVISRSVVLDEREVGGIYEQGGSVETVFYPMYTDNDDETAPENTPSGGDTVQKPTDGDDVVMDEPMEVDGEVTNEREVVVANAPSEMVPRDLPSEPLTETMVFRPGANIRVSDQYRAAPVMRDLPSVVDVPRIQAPETPPVRMMLDDRPHNPSNGSLVVYEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9E3</accession>
    <name>A0A8K1F9E3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Poli38472_013887</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9E3"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000007">
        <property type="entry name" value="Phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF127">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C AND CYCLIC NUCLEOTIDE-BINDING_KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 17" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="21">
        <location>
            <begin position="105"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="20">
        <location>
            <begin position="499"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="20">
        <location>
            <begin position="636"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="788"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="40"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="TMW55125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1111" mass="123699" checksum="67033D91B1C0BA17" modified="2022-08-03" version="1">MGNCCSSEAGATIPHQPNAPGKHQQLLDDSAAVVAPVVTNTSNGTTDRTSELDNEAQDTIASPPSRPSSSSYINSPVKQMARGDSSELDMPGETQTVKIGNYNLRYSYYSKRGYYPEARKKANQDSFYCETHFTGDKEKAFFAVFDGHGQYGDMCAQYAAEHLPVNIAKHLDDNVGILPALTRAHVETNRSMHDCGFDDSMSGTTAISVFFDGNEIHISNVGDSRAIIAQEDLKAPLSEEGHERLIAKPLSIDQTPFRKDERERVKKCGARILTVDQVEGLEPIHENWGLTLGEEIDENGDPPRIWHPYGQYPGTAFTRSIGDLVSEELGVIAEPEILCKGLNVHDRFIVIASDGVFEFLTSQNVVDIVKKFDDPAEACQALVDEAYNRWLQYEVRTDDITAICIFLDGITQRRDLARGSIYMGAEVLDLQTMQRPVRGIGRKDYGSRPTIVGTEAIRLSLTEGIFDAKDLRDIAAENEPAKSDEEIKWIKEIVQGNFLFSHLSEEKILEVISVLKKIDVKAGEVVIRQGSPGDTFYLVDSGEFEIRQLEDGTVPSPGGNEPAEAYGEVVHLYKSNAHLHPTFGELALIYSKPRAATVIAREDGILWALDRLAFRSILMRGRPMRDVVLRLRQISLLRPLTVAQTNLVAEEMKIVTYQAEQVIVHEGNNEPGFFLITSGKVSATSRSESMPTAELKALDYFGEVALVRKRSISQRTLRATERTECLFINKDLLEQVVGKLSSILEKDKIRRTRKERISEARKTASPNSFILFENEETSVDVPKTISDIEVVGTIFSNPTNTVRLVHVKGTSPPVYMTLRTVSKQAIFDASMQTHVCGERDIYVSLYDKNPLVPHVTGMNTNHTDIHLLYQTQVIGDLDTFLDGQSHGESFVRYYAAQVVIALEFLHSEGIVCRTVDPTNLLVDRSGNIRMLNLRLSKYVGRGRTYTVCGTPEYLSPEQIKGEGHNIAADYWSLGVLMYELLCGHTPFSKERKEDIEILNRIASFNPEQIEWPEGTSAELRDIISKLLSPDLSNRLGYRDAKANFAHNTCQAIKNHPFFAGTSWEATKTGSFAAPLEAEAAAEFRDLCSRQGNPEINIGTEYSGDFEWLAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB57</accession>
    <name>A0A8K1FB57_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB57"/>
    <dbReference type="OrthoDB" id="127592at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1151" mass="129225" checksum="44FF6B05DD4A54C4" modified="2022-08-03" version="1">MEKTEHARVIRGALDEIQARRERLARGQVAVSLEPLPATTTATLRDRTAGGERATVSRAGRRPHSPQHEILWITRTLVRLWPKTGQQETMGTVEFVRRATLADVRVLVDEFHPLPQRRQYEFYHPGLRIPIDPSDERNLRADEYDRIIVVALPRPSKQPPAFPSVATRETQVIHAASPFDDQSVQKKQALESTVVPAEQHKPRRRNKSPQETEASSVKELHYENQMIDGVLCDLTVREFEGEGTAGNSATVLEGELAGVCTPLKILPTADVARFISYLNQPRSAKGQVDSVDAGVHLFKSVVSLLRIRGGNLSRDDVSLEVDHPSYQEIRSISGQEQTNLEEEVPSSTAVVDVSCALSDSDMDVTATCVSSPTVIETMPTQEDMFSWYKPRQIRLEILERDSSSIDKFSELKGKPFKVTDAEHSLLGGIYTSDFSTLDSWLADGLEALYFLYHASVTAAGKDKMALDRTRQDRLRWIIQRIVNSDPSVWRKAELRISVVHDANLRSMLLERLVSFSRDRKELTKLVDQAVFLPALMGFMDSKAKQAAKSLSDALLAPTMSEPSPFALDFLAMTKTALDNFSLGCGKLDIFLQDLVFRACDIRKVNEKRAALGLSRVSASGEFSLLTHHQCMLLASDYGLRMRPRWDQSAMVPGKKNRYIFHGDDSIGVEFVYVRRKLDRSQTVVAAVHTFKLLCMGETHTSESKTLAPLNRIQRRFLEQMGLPSLVECIDFFQPGDMRSILEDGLDMQGVTNCLSYIQNTVKITVDSVCDAQRKAIFAVLPLAEALCVSSELEQITKALSEFVSHRLYVADNQVLLYLFALRNILRMFGNHLANMQVSVLLESGFLRRLLVYSRRRSSYVPELASNILWILANSLPNQTTLSAQLQEQFDLHDESRGDLPGLVKPGIVVLMENIQTKLGHVQSIECDAGALAALLRDQTNGVMFFASYRFSHVTRWIDMIRSAGFLSRSDKDRQQSLLDRILRSSKNHGHREGYTVPLTTREKELLQLCELARICLVYFSRSDTSSLLLESGRTKASIIPLLDDKNPLVLHAVLGCMVVHVAAHRDRSSELLEPRIIDRVFGLCFDSAYSPTQAKALLCTRMLMGDIRCLQHPYKLRGRLLQSIQPLIDCLKCTDLDVKKQAIELAVSIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCW0</accession>
    <name>A0A8K1FCW0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCW0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="182" mass="21007" checksum="2BF512D37A9E0B27" modified="2022-08-03" version="1">MDEKRAPTSPDDLCQYPNKFCSNHRVYKSNGKLHRFCELHRAQANENQKRWLRRRVTSKDAKEEQPPAATNRSSSLRRARTARGSAPIKRIKRKAASDAMGMTSLLLEPLNLYSDGHHEQQGKTEDEQKQLEEDLYWLQEMFQGTHEAAAHAAHALGSLSYPYPSQVYFEYTDQCRIEAGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE44</accession>
    <name>A0A8K1FE44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE44"/>
    <dbReference type="OrthoDB" id="70298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42486" checksum="216552274090373A" modified="2022-08-03" version="1">MPASERGTVRGPARRSTESSRALSTSKDKSLSAVTLTKKTNSLVFDVEELKSNLKELQIQGREVAQQDQTLQDVVAKVAALQEAFSSLSDVCIYVEETQKQLDGRLSGLDQRVSGLEKSMNALQSQTNRHEGKRRQFQDASERRFVDSQEAFSKLALSMYETQAELGRVKNTAEHLITREREATNLTQSLESTQEQANEWIQKLRRESSELQAEMMAWKEQSGGACVSLAGDIQSLAKDCSSLRSTVTQQNAQWASKLETLRDAMDRQGKVDKTQLTQRLASITENMTAYELRTKESLGTLLKNHARIRTVVDESMVMCSGEIKALGNEWKTIQEDHRNKLEDLMEQVLSQSIEWSQKHENLRCSVRSLAIQLNVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEK3</accession>
    <name>A0A8K1FEK3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Vacuolar protein sorting-associated protein 28 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEK3"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="9">
        <location>
            <begin position="379"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="8">
        <location>
            <begin position="495"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="66929" checksum="B690F030BACC24D5" modified="2022-08-03" version="1">MSGALHRSPKKQRLSWKLQKRRLQFQLLTNFGKELPASDDVYEQHEQRFLGLLQKLLEIRKSLEHYRIKALPEYCTACATLGADVWCVVSVGAVGKGVEAEKFRHAMCAINETKEMKSHYFNADEVLSGAVRFLDIHINAMKSVKSQIENRKRLKLEYDCYERKVARLMARKSVSAKLLDRNRIKLENAREALQTVTFDLYRVYAKYESERDTMLNGELEMVRQVMHGFYAKNAEATNFVIPEELDRSAVEARTDQLFKQTVAKELEKDPSRGSGVSSTPIAPTAIAFDILQPPTAVCSPPTPPKSQNLTGFTEPQQSPEQPTTPAEPKEAAETPPPPPMPPRASVDDDLSEKLRTIQLSRPKMPQLGRFKNAASFAPSASGGSQGNEEIKLWKDTKDRRKFEDLSDLYAIIKTTEHLETAYVRDAITPEEYTEACTKLISQFKTAETALRMGGFLNDIESFIAQYRLDCPRALERLVRIGVPATVVHNTTNRKTDSVNVAQTVQNFITLMDVLKLNIRAVDEIQPLLSEMMASLTQVSGLPPDFQGRDKIEGWLRTLNGMRASDELDEDQARQLSFDLERAYSSFMAFLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX9</accession>
    <name>A0A8K1FEX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX9"/>
    <dbReference type="OrthoDB" id="41200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="126"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="31416" checksum="08B8912539B7D4E9" modified="2022-08-03" version="1">MTVDKRSITTSKRARNKRAKAQRAQAKALNDAASRPECDGEVSTPTGTASSSSEEENLPTAIAVPCDSTSRLTTIDLGRTSDEDEDDDDSELVFVCRPTMPDFCTDFVPPADEFATQAKMMATGAPDQRKFTVRIPAFRETREGYVTYSISVTTLGESRKQFQLERRYSEFVSFAASLESYLVSPAFQRLKEELREGEAKTSDEEQNEGTTPYAWELPPKTWFRMTKVGALEERRSKLEESLQSLLAEADDVICHTPIVRDFLMLDIFGAQVVEEKLQHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF08</accession>
    <name>A0A8K1FF08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003107</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF08"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="462" mass="51508" checksum="0FD65E42BBA85D6F" modified="2022-08-03" version="1">MSAIIKTLRQTATLAGRSPAAKAFSTSAPSLLETLKAQLPERQEALKKLKAEHGNKSLGEVTVEQTLGGARGVKCLLWETSLLDPEEGIRFRGHTIPELQQKLPTAVEGGEPLPEGLIWLLLTGDVPTKEQVSGLTAELHSRAKVPEHVKKLIKHLKNAHPMTQLSAAVTAMNTESIFAKKYAEGIHKSTYWQYTYEDSLNLIARLPEVAALIYRNTYFGEDNHAYDSSLDYSANFNRMLGFENPEFDELMRLYLVIHSDHEGGNASAHTTHLVGSTLSDPYLSVAAGLNALAGPLHGLANQEVLRWILDLQTEFHAKGLPVNKDTITQFAWDTLNSGKVIPGYGHAVLRKTDPRYTCQREFGLKYMPEDELFRIVDTIYQVMPGVLTEHGKTKNPYPNVDSHSGVLLQYYGLTQQNYYTVLFGVSRAMGVLSQLFWDRALGLPLERPKSITSDWINNHFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFE5</accession>
    <name>A0A8K1FFE5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFE5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="47868" checksum="06286AD8CECF2803" modified="2022-08-03" version="1">MDEETSFDAVLRFLEGQDDAPANETVVTESSLLIGVDGDTSWLDFDAEWAEEGHQVETQGAKPKRKPRRSPHYNPNKSREERRQELLHLRKHTRELELQLEALQERDGALVASNPPGPRVRVWQEIASQQRLQRRIAEEENAKLKEVLAGLVPIRKSFQKIFHKRAITEGMRLCGLSPAQQPATPSYRSSRDFGPDIVRELVEEVQSSGHDIDAICERIGIGLTESSYGDARVRKSESGGVVMEIYQNKVLPFTAQAAGELVWKNFSKIMCEVPFRRFYQREFKNAGTSEDIVIESIGLESKINDTVLETHALQVLRHYVEEDRSAVLWSSANDPIRLGDQPLNGKTYRERGFTLIRTPTTLDPAQYCVLTTCYIITPESGYTDELAQQLQDFLKLDVAAGTAVNHQQIENMLLQHARDQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFF0</accession>
    <name>A0A8K1FFF0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012766</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFF0"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000087">
        <property type="entry name" value="DNA methyltransferase 1-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008468">
        <property type="entry name" value="DMAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05499">
        <property type="entry name" value="DMAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="159"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="518" mass="58043" checksum="5ED655B52A6C975F" modified="2022-08-03" version="1">MSDVAQILGLNGPGGGASGANTGADAVAKELESLKPTAAGQKPKKASGKKLTGMQREVLELLESNHRVNHALYPGFNKLTLQQKWRERKDRPAVKWLRKSFRNPARAELAGEQEHQGGLTLSHWVKAHIDPPDYVFARFNVKCDVFKYTDEEFTSVLANHEDPQMKWTKEETDALFTLCERFDLRWVVIADKYNAHPAAKDGPTRSVEDIKYRYYEVVRLVSEARDRRARNGEKTEGETGNAAMEEAKNESDTNSAEATPEKTSSAQTSATDSPPSKYYRFNVTYEKQRKRQLELAFTRTTEEENELRRLNDELRTVEQQLKKVAVKVDPKKKKELSDVPYEIHREYPKGVHLRSSTLALPQQSKQGASVSTKMLKKMEVLLEEMGVPARPMPTKLTCEVFDSLRQDSIGLLSLRKHLVAKQAEVQTLKERYQTLTGKEYEPIAPPPPARKTGRRASVLGAGSGITAINGTPGMDTAPTHISKGKSLKTSEKQPRSSNKRRGATSSHGIPSKRNKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFU3</accession>
    <name>A0A8K1FFU3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFU3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476432" evidence="3">
        <location>
            <begin position="20"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="548" mass="56307" checksum="663F7CCBD692C81B" modified="2022-08-03" version="1">MKPILCSLLLLVAVDAVAAQASCDEVGTYNVVVDGVSQSFCMTVTPCEGALDDPANPSRTACPGPADADVTGVRSLSIGSCCASISNSNDAVGCVSLDLINDTRQCLAPPSIDIGARRLRWLQSTKAQESQSLLAPTPIEAVDQSDVSFDTTSSSSGDISPEDGEAITFPPSPSTNQPSDTSGDGAIDSSSPAPTDSTPYPTDSTPSPDAEWDDNSTTTTPAPSTNQPSDTSGDSVGDVTYLPPSAGSEWDDSNTSTTPTPVSTTNRPSDTSGDGVNELTPVVSPVPIDSTPAPTVSITSTPSPSPTTPSPQDLWESIIQSILTSTPSRSPSTSQSSDSSGDGLYGWDNKPTPVPIDATPSPSDWTQSSSFGSRDGSSWSGHSTSSASGSSHLVLGAEAEPEAGDPTGLMKPVTVPAPAPTSTQKNDLETLTPITTTPTENNKQDSYSSDQGGMSSTGTHSFSSKTNTNALFLSIIGVIAVMAVAIGALLLRRRSGKPGQTSVAGTSVLTPRDDEDAMFSPIRVQSAASYRLSSTPGNDRPTRPSFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG37</accession>
    <name>A0A8K1FG37_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="3">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_003343</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG37"/>
    <dbReference type="OrthoDB" id="29072at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="15">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="159"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW57418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="463" mass="51724" checksum="545E837219C212A4" modified="2022-08-03" version="1">MENKFIPQAIEIVTLAINEDNNKNYEEAFALYKKALEHFMVGVKYEKNPTSKDIIMKRVEGYMTRAEQLRSMLEKAGGGPKAISSSGTAELEKGDKEDEDETDAETAKLRGSLSSALIAEKPNVQWDDVAGLDAAKEALKEAVIMPSRFPQLFTGKRRPWEGILLYGPPGTGKSYLAKAVATEADSTFFAVSSSSLVSKWQGESEKLVKNLFEMAREKKPSIIFIDEIDALCSSRTEGESDSTRRIKTEFLVQMQGVREARSGVLVLGATNVPWELDPAIRRRFEKRIYIPLPEEEARRVMLKIHLGDTPHALKEVDFEVIAKKTEGCSGSDISVVVRDALMEPLRKCQQAQFFVRCDETATPRPNGAFVTPCEEDPPCAYCHMKLSSCSRECADCKTPCRRCGSIRMRLYDLPSRGFSDDKLRPPMVAMSDFNKVLDHSVSSVATGELDRFVQWTTEFGQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGC0</accession>
    <name>A0A8K1FGC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGC0"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="770"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1111" mass="124583" checksum="EF9B48EAD8F882BA" modified="2022-08-03" version="1">MFDGSFKATRKVSLSGRKKPAFAYGGGPRGGGALTAATAASKEELLQQTKRAREERLEHKRRTTASTKIQAVYRRVLTTRRVRLRVFCDVERELTTLLAPTSGVDIRQTPLATDTLQRFLRKTLFATTTRLLLKDVSVERMTTVQDYVVFMLLVSALRGEATASTSVLTAAKDATWIFQMTKVLERALEVAVMRGTALSPMEQLTNPYVLLLDTLTTQDRYTAAGETSEKASDAIRKVLRQLALTQGFGSFEALRQLVLNDKGVGMDSRVVQVVTRVVTNTLETIVDGSDVDNAVATKFASKMLVTPRSVSNPVVRQVMESIRYPANDRALTEGQFWHVVMLSLSKSESLNWSARAFAVGNVLDLIVQSGFSAHVTETGASVLAALIAPSHMEWAFDAETNPTVLPSEQTDDDDMMEVDMVGSSDLAPLVNEKQREEAERGVSAMQPYEAIVKEQWQQLCESRFLQQCFEGAAMHKMCDVYALFLLAVGRSHFLGVRQSFKAPPASVFAFLSATSSEASALTQGIRPAIVQSLWKLVKGQLAARPSGQRWVADSSDLQGLLLFNVTYSHLLLALDDETFYERSWPFQLAEVSDIVAFLKQFIYDVCWNVSTLVSGGINKDRLQATDRASLLLLPTITTAVKLFNQLYDRDCRRRFTVDGAWLWPSMPVIRETVDLESMEGDLFDVQALLTLSNGSVLTPHARASLILTTIPQVFSFNDRVQLFEKLLEEEKRNVMHLRDEFSRAIQIRIKRDEIVEESFEVFQKVCESHSPSVLKSRIKVTFVNAQGLEEAGIDGGGVFKEYVDNLTKNAFSPEFGFFLATNEQLLYPNPGARIMVDTQKDLLDRYRFLGRVLGKALYENILVEPQFAAFFLNKLLGKFNYIDDLHSLDPEMYKSLMQLKHYNGNVEDLSLTFSVSEMEFGQVVNRPLLPNGENIPVTNENRIRYIHLLAHHKLNVLSSAESAAFLRGFRDLIPAKWLQMFSPSELQMLIGGTANNIDVKDWQKNTTYGGGYHPSQRSIQWFWDLVENEFTPEDRAALLKFITSCSRAPLLGFGQLAPQICIHQVRIDDDERLPSSATCMNLLKLPTYSSKEIMKQKLLYAIRSNAGFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGZ8</accession>
    <name>A0A8K1FGZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000566</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGZ8"/>
    <dbReference type="OrthoDB" id="163233at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14691">
        <property type="entry name" value="bZIP_XBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="243"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="481" mass="54068" checksum="148A8E5346E97D64" modified="2022-08-03" version="1">MSTGLHSAREHLHLPQIGQPPSFLQGDAGASHGQLKPLTLSPRTFGMEDLRDFCGPLGSFKTGLTPRVFSTGLTPRSGFTPRFTTGFTPRINAPGLSAPDTNSFFSRNTGFSPRQNEQVNKISPTGFTPKDVSAMKVPMRFPGQFSNTPQKLGEHQHQMASHSMQQHKPGMQMPQHMPHMASQPNHPGHHHPEMNSMHMPMFDYMNRPVLSPPQQHHPHHISAPMKPQKNVSPMSEDNMEEPEDLDERRRMKNRERVRKCRKRKQDRLNFLEDRTAELEKENHMLKTKLSRSSGAGSNEPLSETQLSELRQEQTSVLFAYMQANNEANTEAFENLAKSVWSERAEIIYGSKNTSVVGVDQIIAAKAAASTVFKQLEIVNHSVQWRENAPTKCVVNWEVEVVLHSEAPTDAPLTAPFGELARFVSPEDKLTIHFISHLTFEDGLIIEEIRQLNLAQMTDGILNKFAPESGKAFQVLRCLMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHR1</accession>
    <name>A0A8K1FHR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHR1"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00144">
        <property type="entry name" value="MPP_PPP_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="28479" checksum="EF582D8E6EA129EE" modified="2022-08-03" version="1">MAERQLKRAHDDVALPSRMHLVADIPLTSRVIIVGDIHGCFDELVELLAVAEFDESKDTLILVGDLVNKGPKSPEVVQFARQKNALCVRGNHDDAALSAYYAWKSGGDDALPAKYGYVKSFSEEDIRYLEELPFTISLPAQNAMIVHAGIKPGVALEGQHPIDMYKMRFLEYESTNEEPAAFEVKPSDSEVVQWATQWKGPQHIYFGHDAKAGLQQEAFATGLDTGCCYGRQLTAIILPTRELVAVKARAQYSAPTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIB5</accession>
    <name>A0A8K1FIB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIB5"/>
    <dbReference type="OrthoDB" id="187748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32943" checksum="81E9C9FB2E3BCA7D" modified="2022-08-03" version="1">MAPTSANKKVVLITGANSGIGYEAALVLAKMDNTHVIVTGRSAERVQAAVDKIQPDAASTSSVEAGLLDLGSVKAIQAYANQIKERGLTIDALMCNGGVTMSQKTFTTDGYESIFGINHLGHFYLVELLRDITRRIVIISSETHDPDEHTTSPPPRMAVSDVEQLAHGYEDFVGGEAYSTSKLCNLLLMKEFVRRFPNGPEFIAYTPGFTPTTGFLRELNVDVAKILMNCEEKGIPVSTPEASGGFMARLCVEDWAVNGWTSDMYIRVHTPYEPSKQSQDEELARTLWDKSEELVARALHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIF0</accession>
    <name>A0A8K1FIF0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009502</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIF0"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="8"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="423" mass="46052" checksum="54BED29937135410" modified="2022-08-03" version="1">MEPTDDQRTRLSVVAFGPLDSGKSTTLGHLMYLVGAVSQREMDKIEHNFAWIFDKRQDARERGITIDVSIGSQTLYTSQRAFTVVDTPGHLSFFKNTVTGMALADCGLLVIPPGSLVQSEELAVVRDQLITASTFGIKQVIVAVNKMNSVGYSNESFDQVKTEVAELMKTTGYSPEMVTFIPISAWNDDNLIQKSPRMAWYDGPTLLDALDNLTPPHRPTEKPLRVTLQDAYKVSGVGTVAVGRVETGILKRGMNVAFSPTGASSNVLSIEMNNQAVAEAGPGDHIGFCLPGVSTKELKRGFVASDVHKDPVQKAIEFTAQLVFLHLDGKLGVGANLVVHCHTTRVACRVKTIIAHVDRQTGAVVDGDTEYMTKGDSWVVVLEPTQPMTVEAFREYPSLGRLVLREQNRVIGVGVVKSVQKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIL5</accession>
    <name>A0A8K1FIL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-nitrophenylphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIL5"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32320" checksum="4DFDF1D0098FF838" modified="2022-08-03" version="1">MTTQRLTSESFRTWLDGLDAVLFDCDGVLWRGKTAISGAKEAVELLRSLGKRVVFVTNNSTTSRANYVKKLVSMGIPAVAEDIVTSAWATVQYMKKQGIQGKVYMVGETGLDDELRDGGYEPSGLTDGDRRANPIPSGIDQDTQAVVVGLDRDISYYKLAYATACIREIPGCRFIATNPDQTYPLDGAITPGGGCFVQFIEAAVGHPPEAVIGKPSQDLLQTVLSTFNLDPARTCMVGDRLSTDIEFGRRGGLHTLLVLSGITQEHELSKIKEPMQVPDFYIDSVDVLNHFHSEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ11</accession>
    <name>A0A8K1FJ11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ11"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000055">
        <property type="entry name" value="pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="6">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="7">
        <location>
            <begin position="175"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32897" checksum="18C0413F2B777A04" modified="2022-08-03" version="1">MFRARQIAFKFVAKEQTEGVGARVRRSIGSYKLDGIDPFLMLDEFNVGLPGGFPDHPHRGFETVTYVLPTSRGHMLHEDFLGNKGELRPGDLQWMTPGRGIVHAEMPATEEPAHGLQLWINLPKARKIMEPRYQEIKREEVPHVFNDDKSVEAIVFAGEVFGKKGPIDTETPVTYIHFILKKGAKLEYRVPEGHNTFVYTLKGEGACDGQTITAHEAVVMDEEGEGVQVTTSHDDGVEFIVISGQPLNEPVVQYGPFVMTTDEEIQQTVLDYKIGKNGFEKARHWHSEISRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKX1</accession>
    <name>A0A8K1FKX1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKX1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="13122" checksum="FD803A3D2F1A3F94" modified="2022-08-03" version="1">MKPWQEELWGWAQVSECHEHAPHLDKRFDRLLVTLEATHEEQRAIKLREALEFVTLWAFVDQDAWKKVVASCGTPWDVYVPDRGSYLPPKYVIVLETRHWVKDYSEKQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLJ7</accession>
    <name>A0A8K1FLJ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLJ7"/>
    <dbReference type="OrthoDB" id="206865at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438477" evidence="2">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="31650" checksum="64ED1D2052B76DEF" modified="2022-08-03" version="1">MRVDLTLALLLLCIAELVASALYDIETVFTERSFFSTTRSPKPLTHPNIQAAAAFAVSELQELSDSGIYTTLKLREIEEAATEVGDFHYVIHLRLALASPYFRSKNATESFEMMVMQSKPIPGPSSEYERSIAIDEFPVMDEDAIEEFWIRMVEKRREERRLLFAQWKKEAKEDQSAQDERPSTPTQVQVGQEPPRKKVKLPFPSTSPSAEPVKSRPKQTLSLDDLHAMPTKQLRRLLSKSSVSNELRTAITSILDERWDQIEQYEASSPHHDLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMZ8</accession>
    <name>A0A8K1FMZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMZ8"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="376" mass="43656" checksum="0B480FFA70F842AB" modified="2022-08-03" version="1">MNRRAAIPSTLHAHFTMPFTKFKSFSEEWNMCGKYDPMRRVNVVSDPKLQRKRLPHLMVEKCVRLQAGLVLDYLRNDLEMLAFLVQYAHATQSVWHHNILQLRGYFVFNTKVYVFYEYCELGSLRNAYIRDSNPLLRLQARTNEQEVRRVMRQICQATKYLHENGIAHGDLALENIFVTNRNVCKIGDFDHAVFVGPENQRYPLKAFEPRRPMYAAPELYMHTGEQKMIDLFKVDSWALGIILIMLMTKKPLLDSAIDQDTSYQLYKRIGLRPYLRAMYLEQSAVFRFSDDMIQVAEGLLEINPLKRFTIEQVLACVWFQIDDEEDVEDDEEEDIAKAVAEEVVEGEAKVEEAGGDGMGKQGQDDGEDSSDDGFYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNC7</accession>
    <name>A0A8K1FNC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNC7"/>
    <dbReference type="OrthoDB" id="6131344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="364"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47790" checksum="51D474F1906111AB" modified="2022-08-03" version="1">MEEATLALFQVAAEGDLAGVQRFFTLETTARIIAQTNAGHRARSDAALARNESPFRDGMSREGWNAPQGSPSRSFFDVVISNDHRHILNWFLSSDACRVIGDTMRAIISSIATTVILDRPRDSFEVLEIIFDSYLFVKVLTPMERKHAFYDMSHVACFLNLPDLLRLLLAHGSDANIADARGSLLEVCGVFGSVECLEVLVESGIFGVQHAITTDWNAPFRNVEVALALLQIGVDMQCDPNRGSPLHVATRFRCDDVVETLATLGYVDVNARYSTTSTRTHQGGTFVYTIEDMTPLMIACLPSEYQRPGFATASVLVAHGADVRQWNRDGETALHILVKNKFDADIVALLVATDPEVINLPDQEGNTPLHLMLQTMELDFAAQSCDVLLSNGADPYICNVRGESAYQVLMESEQGREYVHSHPQYFTKPSSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNJ7</accession>
    <name>A0A8K1FNJ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNJ7"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF232">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYB3R-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="85"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="137"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="414"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="59433" checksum="52C974901BBB7056" modified="2022-08-03" version="1">MSRKLEMLALDENEVDVHGMRGAMPVGHMSHEMELMTPPMGHSPDMTYVRHPSSTGSSTATFSHMDDQFTEEDEDSSGPKGRRKSDSNCKRPWTREENEKLIQLVKQYGAKRWSLIAMHLPGRVGKQCRERWHNHLNPNVRKDAWTAEEDYVIFECHKNVGNQWAEISKMLPGRTDNAIKNRYYSTMRRMQRQSLRKKGPLREGKSIRVATVNSSSPMSSPTVSTPPPSRSPPTQRPLSQTTTFQKLFSSSGEVDRHEQDFVPDFERESPPAPPTRHHSMVYPLSNGYSNSDMSMSGQSQSFDYGPGSNHRVRAASAPSSLSLMGMMGNYGGQYSSNEPPSMYASSGNFPGEPGGMFPPRHSHGGSGNHPSSRSSDPPVHLSHKRVMDEFSSGPRDSWKNESPVSVTARIFRGTQQTQSQQQQHVQPPPSYNEPLGPPASMGLSNDSYKPSLSLPSYRSASSMNNIGQYGGMDSFQPGMNGMRKLPSPMFGSSSANSGSLGGMSHGGHSDAQFELFNLEPFDNDLRDNDFHSGNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ29</accession>
    <name>A0A8K1FQ29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ29"/>
    <dbReference type="OrthoDB" id="432686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="31924" checksum="5223F2D90E2DD0ED" modified="2022-08-03" version="1">MQDQADGWKKVTDAVHAKNGKIFLQLWHMGRQAHSSFNDNIQIVAASPIAVSQGQIRNAHGEHTGFEVPRALETDEIAGVVEDYRKSAELAKQAGFDGVEIHAANGYLIDLFLQSSTNKSTDKYGGSFENRIRFLLEVIDAVKTVWSSDRIGVRLSPNGAGGEMGSEDNAETFTDVLQQLSTHKLVYVALLDGFGFGYHNKDRLLTVFDAKTHFKGTVFATNSYTRDTAEGVVRSGSADAVDFGRLYSNPDLAERFQHDWPLNADAAYPDYWDTSKDADVYTAFPAYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQU4</accession>
    <name>A0A8K1FQU4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="19"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="417"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="450"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="483"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="703"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="739"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="773"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="871"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1005"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1038"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1104"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1285" mass="137953" checksum="4A1AC640FA5674DD" modified="2022-08-03" version="1">MSSSSPDASSADTSALLAAVRGGQREALERLLGTGVQVENVVDENGDSLLHVAATRGVVAVVRVILDTDGGMSLLEKPNNDGKTPLHSACSVNKNAEVVAELLGRGANGNAVDNESRTPLHLACQAGARDMVESLVKHGVELNYLDRASESPLHYAAEKKAEDQDIGILKLLLDAGASVSIAERLGTALHRATWSNWLEAAKLLLDRGVDVNAQDTFGRTVLSVAVQQGYFDLTKLFVSHGADVNKADLEVDLPLRNAIHHPRAAEVCKLLLEHGALMLYRYGQLPLLNEAAERGNVELVKVLLAYEDKNALTPEELGFALILACLSSRTAELAQYLLELGASTTVKDNELGNTALHNACMARDAVLVKLLLSYGADPNAVNYHGYATFHTACAVDNNDEVIQLLLDRGIDADEQVSGNTALVIACYSGAVKTVEKLLAYGVNTTINREDGQSVLHIACSRDAPEVVKLLLEHGLDLNLRDESGNTPLHVAALEERSAVVQVLGQHGADAHARNEDGFTPLTMCVRWQNCEAVDPVSALETVYELMKLGAVYEDSPDNCPDTFRGLMAARPGTQEDWITYSELAASVPICIKHWTAEREAGKPLTQIPSDVAGNGGPALEREPTGDPAHLEATFLVPKTGQVPVTPKSDLTIDLSVLKETAMSSEHTQDTVTALFAAVRSGHLEDLQHLLDDQIDVESIVNEDNESLLHVAALEGRIDIVRAILEANGGGSLLEKPNSEGETPLFYACSTSDGLEVVKELLTRGANINAIAAMNRSPLMKACQQSTHEVIEFLVLSGADVNVMDASGYRALYHVCERHMIPTALFLLKCGAQVGLADGLSMALRHMLNENRIDETEAILKYGTNVDDTYPETQTVLQVAIQHGRMDFVKLFLAYGANANAWYFERERPLRLAMERPEAVELVKLLLEHGATSQWEEGELSALNAAAKTGNLELFELVLAHEDISSLTSKALGKTLIAACDNGKNVQLVQRLLELGADTETRDDDVGGTVLHHACLSGNASVVKLLLSHGADPFAVNENGHTALQVASIKVDSGEVIRLLLDRGVDANQQVSDLSPVLLACGIGNTSGAKALLAHGVDVTVTTEAGWTLLHLACKYKEAELVQALLDHGLDPNSRNMFGNTPLHITAFEGTVSVVPVLGQHGADVHARNEEGKTPLTVCVTADKRKVSNHPIRVLGVAIELMRLGAMYEASPDNPLNTFDGCRVLRPGTDSDYVDMPDATQSVAICIQHWASEQAAGKVLTEVPTDVVLNGATAVQSYLEQTTTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR32</accession>
    <name>A0A8K1FR32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006035</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR32"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="259"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="135"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="38617" checksum="7F284096DF64A41E" modified="2022-08-03" version="1">MDRTSDFVKITVLFDTGGSKVHTHRPLSQDARRAQQIADQLRQQELFLRDLQELVGKKSIIGDDPTTQIATLTDLLKKELTAIDKNIQMFQQAVVMQRGRHQQHHQAHFTIISQSLKMRCAKNVKQFHQALQQHTATIRERSSRRSKFSHGGSTPMVQLNAPLFARTPSVPPPAGNNPFMRPNNDPARAPLLNPNGEANSGPPQMPYPGAGPSQPAVGVGLRRRAGNIGSSPFMQQQKPPMGGPGGGGGGQQVMQYYPRQDAKTRRQNAAQVESTIVEITGMYTQMATMVAEQGEIISRIDDDMNIAQANTEAAHGELLKLYSMVSGNRALILKLFLVLLLVIFLFVVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C202</accession>
    <name>A0A8K1C202_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C202"/>
    <dbReference type="OrthoDB" id="427735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="55420" checksum="2D4141EED29222F2" modified="2022-08-03" version="1">MLQGGPGASSVNLENSMTELYMRLNGTTSVYTMDHRGTGRSALLKCEAAEAFSAGSPGGAEVDMREVANCVKDVLYQIEGQTAAFSVTSAAKDIEFLVNGLNQDEDVFVYGASYGTYLTERLMHLAPSIVKGYILDGVLAEEKGNFAHFGSIREEPAQYFGQLCDQDKVCRSKYGSDVPVDQAMYDAWFETYETLDAAAIGDNACADLLTTREDIMPSWVLGTYFSTLFSIGDVSKRAGIPAVLQMVRRCNDADVVTLRALTAAQGMTLFDVLTQAGPLQPFDEVNGISFLLMHLIKHSELWLYPTPKWEVETALVEQSVFGTFYTVDYAWHCVLSGNASDPSCPALLELGQQRTVPVNYSSVELTKFSYERDEYFGKTAAIPKDTSVMVMSGKLDFQTVHSWAVDQYEKMQGDNKLLVEFEYGPHCSGIAPSTAGDTTGCGVRIIASFVKQMGDIDLTDLSCLDELPAINFDVDEDLKQYIASLQTGPQGKHKQLKKKHHVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Y6</accession>
    <name>A0A8K1C2Y6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3 8">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_010370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3 8"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Y6"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000032">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000114">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500133">
        <property type="entry name" value="UDPglc_DH_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="335"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="93"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="279"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="52512" checksum="15CB2E1CC2722D4F" modified="2022-08-03" version="1">MTTQEFKMTVCCMGAGYVGGPTMAVIATFCPDVKVVVVDISEQQIAKWNSPDELPIYEPGLKELVDARRGKNLFFSTDIDRYINEADLIFVCVNTPTKQSGIGAGSAADTKNCEACARKIAQVATSNKIVVEKSTVPVRTAESISAVLSANSKGLQFEVLSNPEFLAEGTAIEDLKEPSRILIGGPETPSGHEAVEKLVWIYNHWVPRERILTTNVWSSELSKLVANAFLAQRISSINSISAVCEATGANVYEVAKAVGADERIGSRFLNCSVGFGGSCFQKDILNLVYLAETFNLPEVADYWRGVVTMNEYQKTRFATTMIRRMFNTVTNKKICLYGFAFKKDTGDVRETPAASIVKTLLAENARVAVYDPQVKLDDMLAELAYQGVSEKTHPNLHSLLTVVSDPYEAAKDAHAIAALTEWDMFKTLDYDRIYASMTKPAFIFDGRNILPHDKLRELGAKVYVIGRADVIAHELPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C325</accession>
    <name>A0A8K1C325_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C325"/>
    <dbReference type="OrthoDB" id="121234at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="246" mass="28065" checksum="CFB8687A3B592F29" modified="2022-08-03" version="1">MYPQSLQKQVEKKKKDAEKKFSSWVFNKFKKNKTQFIRDQDERTIDADRRRRKPSGTRLEAVENAANPSDGQTPLQRQQNYLRAQLLEMKRQSHESLTSSRKRHEDEEEEQPENNEESPEQSEKTDDGDCDAKPAEDPAAPGDNQEEAAAEEIKDEEHVDVVPRRKSTSGDSRHSESGSHRSSLSEEVVGRLTTATLLYEEALHALDEALNPNQVQVRPSQIISNKTRRASTAQKGVFAIPDNEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C378</accession>
    <name>A0A8K1C378_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="239" mass="25924" checksum="39BCC366EF5484C6" modified="2022-08-03" version="1">MQPFPSGLASPFVIDVSASARVRDLLKLMDSSSEDASVCTLYVAMGENSLTAFARNADAIRSLMRLRMGETVAVLYPRSGLGGNARVHVLFQTVQQGSLEDASRPSSRAQQSWYSRFLASARLGFSFLRTYAASAMLHVQLLLEIARGLFVSHFAISLFAFMITASFAGVALALSSLFTSVQDTTGVDSSRLLSMIILRTSVDTIFSAFAFIQKRDIESTINLFYDIGIGYGLALALMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3M3</accession>
    <name>A0A8K1C3M3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NAD kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3M3"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000017">
        <property type="entry name" value="NAD kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="62488" checksum="1B52BF14243A5F77" modified="2022-08-03" version="1">MNAFLKCDTSSDKPGSFGLPSPPASTASTVMCTPTSTEMRQSFESAITVPHHASTETAIAKTPSANDFGCYEVHDGPHRKLSASSMSGYTLEDDIRSIGDQMKRVLAFCEMQSQSPIRMQAKINELQEQLQLAIAEKNYWMKRCHEEMSRNSQSIAKDLQIVKKHPRKRTNSELIFIANTMGSPGEGIYQDDGSSSSESDSSGEPIVLTKSPFRLLQCSDEQCEVFTPMNRSIRTQHRARNNVQFLWDEKPKSVLIIKKPNEPTVTDTLVRMTQWLQQEQKLNVYLEPTVHEELEIPRTLTWESEEDWEECQTNIDFVISLGGDGTVLWVSSMFKKSVPPVLAFAMGSLGFLTPFDVENEVDHITSVIKGGFYMSLRSRLVGTIIRKNKECEPLPAVHALNEIVIDRGPSAALVELDCYCDGLQITKIAADGIIIATPTGSTAYSLSAGGSMTHPSVPSMLFTPICPHTLSFRPLLFHDSATLKIVFPMTSRASTAYVSFDGKNRVQLERGDSIIVRVSSFPLPAICRINENQDWFESMITNLNWNQRRAQKPWSETSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3U4</accession>
    <name>A0A8K1C3U4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_008594</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3U4"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16702">
        <property type="entry name" value="RING_CH-C4HC3_MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000287">
        <property type="entry name" value="RING finger membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="829"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="874"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="911"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1046"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1074"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="15">
        <location>
            <begin position="31"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="216"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW55946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1126" mass="128231" checksum="647DF684FBB984FE" modified="2022-08-03" version="1">MNHVDAEVIEREQQEMEERVVSTAMSPMLDEDSDDEAECRVCRGEAEPDRRLFAPCKCSGSIRFTHSDCLEQWLEHSGKAYCELCGYKFEFKPLYDANAPDVLPWTELVSTVLRMVCFKWVPFIVRAALVIVLWLGVAPWCTSWLYRMWLLRASAMVNVNFSERFDSDHVVADIFSGILLIVVIIFSFLALMSFADFLRFHLDHIDDPIDDIHMQNVQPVRRAPDREGRQENVDELLERPDRRGVPAGLRPLDGGEESDEDVDHHGHEEGNDAMPFHGVFAPHPREDLGLPEIGGVQHQGPDQELRHRRPVRNADNVERNAGRQDNVAPLQPPRNPAPPRNRPNPPNNNQNREWDDDFEHMEINIAMDELLGLRGDIVVLFRNVSWLLAFNGAYLGLFAFIPYTLGSTIMSASSKILAALPITPSIVAFFELSQEATMDELGIAPFIVRSLLNAMENAKKSGDCLQLVDLCTCAMGYLSICFTIVLWRWMVTTASSYIHRPLMGGLLWALRCLTAIVKVSTLLLLKMVVLPIVLGIGIDLSTLQLFEVTVQERITFCMQNMVGSLLIHWVLGITFMLFVTVSVLQLREVMHPDILAKVIRPQEAHPDLLRSLLSEKSVKHARRMALSLLIYAALLVVLIHLPIRFAKAAVPQYFPLELRFQHYSPEVQVPLELLVVHLVVLAILEHAKNEIGRLQHLGIKFIAEQLRLTEYLMPRIEVTRNHQRAAHVLAPPPLHFHPHAELPPEELRVDGHRYLPWPEDGLDDPQPTEYDLLPRQTPHYVRARLATLLVVCWFLLVTTVGGLLFGTFLLGRVCMGPFERWTGITHDPLAMAAGVQIMWYLVNGLNALNMLTLPEDQVERALINRGYTVKNMNVDNAMISVIGWAFICPFLVGYIVSSCFPAANASWFEGFWMGYLVFNLFVWFVCCFRTKKNRRRNNRRDDGMNDGMFDEDFEDFDDLDDDLDDLDEEFEEDDQHVAHELNGVAPPAPGQDELEGFIASLKTSYKQLMFTITVHHNDTVRLRRDNIRDRCFDVEFFLEKVLYPGISLLLVIFLLCTVESAVIKYIWASPNSDLQNTAFATAVIGTAAGAFLLRSHTFVTKWMGDFAESIRNERYLIGRQLQDMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C469</accession>
    <name>A0A8K1C469_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008738</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C469"/>
    <dbReference type="OrthoDB" id="412182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008686">
        <property type="entry name" value="PRK11705.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF1">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="47488" checksum="D91A2F2F00E6C7F0" modified="2022-08-03" version="1">MSVTLKQNPALVAASVVGGVALGSFLLRKAMHPVLRARAANFIKQMLADADIIVDRDIKVYDEEIFLDWVNRGMLAIGESYMAKKWDSIIPLDELLTRLMKLPADKKRKLFKSWNSKFIALGAHLFNYQSPSRAGIVGAHHYDIGNDFFKLWLDPYMQYSCAYFKGVEDLSDLDKAQETKLHMIAKKLKLEPGMRVLEIGCGWGGLACFMAKHYQVHVTGITISNEQLKGAREWAAREGVSHLTSFEYCDYREMRGQFDRVVSIAMLEAVGYKNMDIYYSVIERCLKDNGLALVHSIAANRSLKVPNQLWILKYIFPNGFLPSISQMLLFTERKLIPEDVHNLGPDYDKTLMCWNQRFQEHVKNGNIKRSEVFLRMWEYYLLYCAAGFRARTIQLTQIVYSKKRAERYDTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4H2</accession>
    <name>A0A8K1C4H2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4H2"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052812">
        <property type="entry name" value="Plant_DnaJ_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44272">
        <property type="entry name" value="DNAJ DOMAIN (PROKARYOTIC HEAT SHOCK PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44272:SF3">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="46511" checksum="4113CAECB02C7FA0" modified="2022-08-03" version="1">MSSAPVAATPADTFNYYQVLGVEKTASELEIKTAYRKLALKYHPDRNAGNEEASDKFKQVSTAYAVLSDPNKRRQYDVAGETGKDMEFESVDVESMGGFGRVVGALFTKIGLPIPTQISQSVLTAARDLCDERSNATQKEPVTAMSYGSERHARVEKQGAHFYRFTVEEDRESVVLMCRSASKSKFKLVLFDASGGVRMVQESAKRSKCTAADMFLSSSIELMDLHEMWPPHLSGSDSELPELFTKLSTFEVKRTIVLEKGDHLFCVYGDNWLSQVRYSIKVLKIDPKSTGLREIQDHERELVGIKLELDTLQKEYLAAKKAFEEVAGRVDATQKRTDDLLVAREAAYDQFLAGSSVPVNGNMGAPDLHRSSSRSSMESNGSTSNGPASNVKSIFGGFSNRLFSKTDGARASPDASQSNRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C533</accession>
    <name>A0A8K1C533_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C533"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="830"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="969"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="803"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="917"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="545"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="635"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="803"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1153" mass="123885" checksum="5C3E5B71CB9BB1EA" modified="2022-08-03" version="1">MDARVASSPTSSGFEALKHTPLTIQSPKTPTVELDGGGFAEESSFAEDFDLDLLVAPSLGVAPPSPASLSPASSTSSLSGFKTPETAGTLLSPPHSPPPLRLDSKSETSPGAFESALDRTGLIYWQFLGGKLKTSESSVVVRRSTPAVSTSVSGLEKSGLVYWQFLGGKLQSDRRTPSTRVAPAGFNSPLEQSGLIYWQFLGGKLKSQSITSQTSSSSVRFESALEKSGLVYWQFLGGKLRSDSPAFESPLHQSGLIYWQFLGGKLKADTSSSIRTKSNLVASFRSPLERSGLIYWQFLGGKLKGEAKAIKESTTRAVAFESPLNQSGLIYWQFLGGKLKSDARPTARAFGSALEKSGLVYWQFLGGKLKGQNTSSSVRFKSPLEKSGLLYWQFLGGKLQTDRLKPVSHNTELGGKAETAVRAPTSVLHQANPSAKHKTDAPALKSVLHQTGLVHWQFLGGMLKDPATPSPVYQSVVQRSGLVYWQFLGGKLKSDKKTTVASTSVNPPALALEPSKAPASEEESFVAPILAPVSPRFVGEPKSPKSPVSSHSARNSAMSSPKAPSSPKSPVAVPELVVSQAPASPRSPAPESPGSPPVSPAGTPAGPAPQSPKSPVPDFNLDEESAVPQSPSTPGPESLEPSAPSSPTTSTPNLEPQESPITFSQLPDFFPMGSPSLKSPPPGSPRVPLSTPLASPLDEVEQEQSPTRMKKAAKAANVYSPNDTENDEDMHSDDELGTPLGAAGGGFGDYDDEELDFSSHRFIGPSVAGDDRSARALHSLRRVLIHAKPPRFASEAAAQSLASFPSRRSSSAADSEYPDRSSRSSSLENSLNVYRVTFSEPNLGFRTRISVSQSGADLMVQVASVDRDSAAARAGVVAGDVLVSVNDHGIEPHMTEEQVEELFRSLPAPRSFVFSRNYEDRSSSKGSNKGSGVFERRGSNPLSHRLSSAISFGSSILGSALKRRKAVVHKDVMCDGCGVESISGALWSCSVCSHYNLCTDCYEMGTHGMEDTEAMQMLNEAIVQHKLQKKCKHFTPEFLLSLRRDVCKNRPDKFEYLGTWIADIVNGKSATKITVRGIEIPNLHPTARQRFVSKLMVVVSNRTDIDVNIEWLQDDTTRASTLEVDDDYPQEDLEKLRIWISDKKTRIASPFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C595</accession>
    <name>A0A8K1C595_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C595"/>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="628"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="631"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="823" mass="91165" checksum="CEAEF940B9B12A36" modified="2022-08-03" version="1">MRLSAVATERVGTNYATTSPETDLGSPSFDAKQYLAVTHACTSYSSLQDGLKELKRTTSDKTEQLKALVTAHFDQYLTCHEAVRGLSDDIRTHQKESDQLVTDMKTLKQVTDSTLSVMLQRAKEQRRIRNTLAVLIRFRPIFEITTKMKESLQSKDYEKLAEDYCRLKFHHSKTHIAALQPVLAAAHEVARKANTELLQHFDDTSLSVKDQKRAITVLEVLGLVEKPIVTCLRKQFDYLEKRLAALPPDGQPAKVISDCGAVIYRFRSGLWGFICDVFKPVAGGAAAATVITSAEAEVIQQKAWGILARAVELIEKNSSPPTAALLKQLNESFREILSLKNCANATLLNDNITQLKSSFCEKFRIKIVLQFIQQTCTKHRESLMTEYFEAVVRIPSMTSESSVDLTTTGMDETAPSSNGEDTIKVTRLISEACNVFDEISNTSMVSSESKVHIYRASVLTACATDVMKRCENIWNQLGQVLMEMAEGTDLIESSNMDTKAFRSVLVGEFNHQLHSIVSMFFNTLLDKFRAAVLPPTTMASVSGSARNRAGPGVCVLFAIVSNCIQLREKHLGTVEQWVRQLNGGANASNSSEIHQLLVGIESKCVETYVAMHSEPLLRVLNAGSTEEAQQTRAFAAPPSTSASASRTDSLRLDSRTGSSTALFNIVPPPTPTAIAAAASVGNSIPQDCRQYVFNVLLQLITLRSEVESSLGQHPVQCLEYMQSVSFQLTAILGRYLHESFTKLEVATEPSEWQRIHLLVEARFFLFALRDLLSEDTKIQLIAVEKTLEKTKPGEKVAMAQLQLLSQLKHQTKLYLLALQQASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5C8</accession>
    <name>A0A8K1C5C8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5C8"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="214"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="388"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="522" mass="56181" checksum="B1F5553CE812793B" modified="2022-08-03" version="1">MKFTRRKAPKVVSEVSETPIVDVEAPEPAPKKKASSSAVSKAAKAVPQRVSRSVSAASAAVPKKAAKVKASVASAGGKLKKKMQRFSLANVMGRKGGPDGDIRPSVISVINLNKQLNDEVSRNDVHFFFGPQQGIFEGKDSARVLHGERRIFKNAKKFWLMSEPLSLERDSTSSLVSEPTSTKSAPGLGSTISAAGRFIGQKVAQMKLPASHVNEDSFCDGCGMDPITGNMYTCSSCDNYSLCESCYQAGIHGYEDSSLLKNVREDFALRNIVEHCRNKVPEKVFDVLMKKVCKGQVDKFNFLATWISSVVLGHPLHSLSVRGIEIPHLDAETRASLVQLLTPVLAERTDLEVCMEWFCPEGDRDDLPSAVRKQETLRIWVATDKESKSPFASKDSARDGGDTESDHSPNSSPDLLLSPHVGSPTTPFTPHGDMLGSPPASPRTDGSLSMPSSPRSDRSLSPPSSPRADVETVSPPGAPQFAALSLADKTETVNDDYQSDSDVHSESSVIAVADNSKGGVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y2</accession>
    <name>A0A8K1C5Y2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y2"/>
    <dbReference type="OrthoDB" id="88517at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="entry name" value="tt1808, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="22827" checksum="E94733442602B39C" modified="2022-08-03" version="1">MRGWRMCAIQKDCILTKSRFHVCLRNTESSWHFLLRPDQTMRKLPLREDYPSVSLSQLFDYIETHGPIVHPVLGEMSRFLSYEREFLPLPTDVPGRHEVVAQIHKDLSNWRKYQRIRGYIVLEQCGKTMDETIVRMPNVSFLPTDDARGLQNIWMCDGDPFAPTFVVEVNTLRGPNSQFDALDAKMRHEYFTHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y8</accession>
    <name>A0A8K1C5Y8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y8"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF69">
        <property type="entry name" value="FI18408P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="3">
        <location>
            <begin position="142"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1107" mass="126332" checksum="360B2E64FD24F4C9" modified="2022-08-03" version="1">MRCLVMNGAEHITDIGLQAIGEHVPTLEALEIANAVKVSDAGLRALAMQCTRLNRLNLSSCSGIRGAGLAAIAEHCHSMVDLGLAECHQFEEWVLLRCIYSFTSLENLNVARCPQITDYLLKTIGQQCPKLRSLNLAECHQVSDVGVVQLAQKCHFLARIALCRTQHSEKITDTTCAALGEHCPVLEDVNLTGCNFLTDASVRWLAEGCTHLQSLDISQVFHVTDASLRALSEHCADLTSLRLNNVKNVSDVGLRFLSMGCPRLESLHVSNLYLVSDGSNRDFGLEGLQAIAKGCTSIKELNLSGCFQLVERALIALGSSCTKIKKLNLKACPRVTLLAVNALLHGCPTLTSLNLSGVQLCNNAMLAAIASHGVALKELCVAQCDKISDPGLWHLARRADQFETLDLSGCNLLTDIGLNAFLDGLQKPALTHLHLAGCTQITQDPIARLAFVCPMLLTLSVQGCRISARTLHSLSSSWPFGEVRVPTGIAATQSNAEFGIFPAQRAKDRRYVEETCVFWAAAVKIQNLFRARLARRQALINLEEARRLYVARRLQSIWRGREARREALLRKLFQSGIHKSAAKIQRRYRATRQARKAHTQMQAIFEKEFEKFVVLVQRRYRAKRAANVANAIIRARRKQYEREVEAAIIVQRRFRGIVGRRRFNLVQLQRLAREREEQEASKRLQAIYRGRMDRMKAKQLENERRLEQEGRNQHAIQIQAQFRRHLARKEMERRREYRKYVEQSVIKLQTAYRARRGRREVDILRLAQQQLEAQRAAMKLQTHWRGRRARSLVATLRNARRLQEELEIRSATHLQRTFRRYLIRKWARAVMIELIRAKQADHAMEVWAATLVQAHWRRIQACRELERIQIENRTRWKHLIDTYNQHGCGYGAPFYYNQVNGEIRWRMPREILMLQPRPACNQCDATASASVECATCCENFCEECNVIVHGNGKRRLHTTRKLFNIYGIRCDYGDGEFPSIWPTEMEQDHQSGYDFVNMAPKENYQDMLWKIAQFEPVVTGKWLKEVVDTTSSPVESHVSTDETVFDPRGLLYQEDDVDEHGNSLWESFYDYTRGEYRYYHRVSKRVTSEPPHPQPSALTPPEDISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6C7</accession>
    <name>A0A8K1C6C7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy protein ATG17-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6C7"/>
    <dbReference type="OrthoDB" id="1937984at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007240">
        <property type="entry name" value="Atg17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="7">
        <location>
            <begin position="160"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="302" mass="35004" checksum="3A5E2D3E8510DDDB" modified="2022-08-03" version="1">MAQHVTAGYFVGAVRDVTHTITEKCQVLKTLLESSEAKFRVLEHTAHTKVFQETPLIDEMDRVFQQLRMSSVSRSFSANESTGATLFDYVDAETVQSLQHDALEQTKEIEEMLGMHRHALTRIAAIYQYFSSFEKRYAEQIHRIRHSTEEQAASLDSKTLEQLYDTAVRFFVDMEQCDRFLVGYFSTINDVNPHYELAIAEAETLFDELRSLREFYRHFVASYAQVGPELERRRRHEARVSKLIAETMNKLHALEQEEREARMTFANVHARFLPSSLCPELKDLPPQFAIVQVENHPPRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C792</accession>
    <name>A0A8K1C792_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C792"/>
    <dbReference type="OrthoDB" id="77957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="1">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="29010" checksum="D388BF260BC92B29" modified="2022-08-03" version="1">MSQARVAAVARGSMEVFDDVQRTRHQIETDFTRYDDRQVRFKKQFDRETRRHNHAISSLACAINSTPGSNAVLFAREDNDDFEEIPAGGSNRRGSVVMQQLRRLRDPHAQRRREQLQCFYLPPVATTDLICDTCGSFRTAAIVHPLPEPWEEFVCEDNGKRYYYHRLTKQILWTPPPEASPFSVFVFERTNSVFTVCRCIPSQERRKRCMQKFRMYALETARQETEKRNRQLHGAFKTLAYKVIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C875</accession>
    <name>A0A8K1C875_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013544</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C875"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="21"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="25"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW58070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="308" mass="35206" checksum="A0D1EDB18169650D" modified="2022-08-03" version="1">MHALIKGVVRSYRRVAAQFLAPLSCPICLEPLPVIGLREAAEDSTETHVKLLCRHKFCTACIGAYVEMKVKAREVEEDQLVCPVVECKACLKEGDIAYIGGMTTLRSYRKTLKRVRDEKNPSARWCPRPECGELILCESTENFTCPKCQAVGCFNCRGYAHRFWFCRGTEDKSYLDWEKSVGEGRAVRACPQCQMRIWKSEGCNHMTCTHCRHEYCWVCETKWDPSHYSCYEVTFLGTSYFARLLPRVFGYSTIVFIVLVVSIYGFALFAGGYVLFCVALNTVQRHIHGHRRPLQLNLDPVDAHPHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C879</accession>
    <name>A0A8K1C879_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C879"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:002286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="312"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="591"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="387"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="667"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="439"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="543"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="682"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="703" mass="77764" checksum="E5EB40DD66786FB1" modified="2022-08-03" version="1">MWLCKWKADSHGVVGSRRRRQATTATRKYLTMDTESKELMREWLVRSLEPVCDADPEVLSKYVLALVQNNPHKEGLQETCITKLEEFLGDETTPFVARLFRALETGEYRNEEGQEQEAQASTGQDDRDDSSRRRSRTGSDDDDEHRRFNKRRRDDEYSRDYSPREGGRREGYGGRDGGRGARGPREWDREGRERGYPMDRRRNYPPEWGMPPQGMGMWPPHPHFPPPRGGFPPHPMGDFDPNTYNPENPGMMPPPHMMMPRGPFYPYGGRGGRGRGGYHGGRGAGGPKTDGEGASPGEANGAATPAPVGARTTLRVTNVDPKYVNMTKLSLHFSKFGNVVNVQMRPNYRCAYVQYTTEEEAKKAFHSPIPVCNNRFIEVKWAKYDAKDPQGAPSEETEEGKSAAGEDGKTTDGESKTEEDQSAVDTTPEKEMTPDELRAAALEKGRKVLEEKRELLEKQRQLMKQKEELLKRQLAQQKELLERMSQNPASVSAAEKRELLTKITSLSEELKALQPRRDDQNKLTGLKAELSALEAEAASTGAPYGGRGPARGGGRWTPTGGRGFYRGGRGGRGGGRSPYGHYSNALDNRTTIVKVENLPEEARDPSVLEQHFGSFGAVERVVVDASAPDQGYIKFQDRYSGQTAMTRGGVYGETQLQLSWVEAQDAPAGLANSDSGAAPASESIQASDANTANGESTEVSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8E9</accession>
    <name>A0A8K1C8E9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8E9"/>
    <dbReference type="OrthoDB" id="3046016at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052267">
        <property type="entry name" value="N-DRC_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690:SF0">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="620"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="902" mass="101062" checksum="8B6C61EF55AE8190" modified="2022-08-03" version="1">MASSTYDRRWQEAMAELNEQVHIEDHTLSADGQEPGTVEAPPQASIVEAFQHYACLYIKYIQILTRLSECYDQMVHPQKRIDVKQVMEVVTTRIVELKHALVKWNPPNPDVRTNPERSFPWEYVNLDDILVDLKLPPETLEVPVPKSFLDDQAEELLRRERLVKGYMKLKHGVDVIYLDSMEDPLALHDALSLDEAIAIIQRNERGRQGRQRGLLVQELREEEKQRRIYEAAQTPEMDPDIAAANIQRVFRGYHSRARAQRERDEELIFIGMKPSKTDRSTLEKRLADARLQRKTEQSENKDEYERALVDLHGVVTSEEGPFVKERMLEERRKWITDVMATGQLPEDLTGFYGSGMTEEEAAAAAAAAAEAEAKAAEAKGKGRDKKGAKKEEKKDKKGGKGAKDAKDEEEEAPEKPPPLTGPSELCGKLAMAVTGYEKVWLERDELDNFYQKYDVALAKDVVRGPVEVQIRQQVDEMLVLQLANIKAQLEAAAASGKKGKKGKKGGKKGGKKGKKGKKDGKKKGKALPGDKIAELKGRTPDSFLPMLVEQKLVHTPRVHHIQDFIGSFNFLGTVYQNADRRDRFGNWVPQDPSAAQLRQNLTEYAILPLSSNLVRVKTPHVRSLMLYGPKGAGKTMLVSAIATETGALVLNLSPSNLVGKFTGKTGPTKLVHMAFMLAKVPSLQPVIIYIDECEQIFAGGGGKKSKASADGPTRFKKDLITYLKAALEPQDRIMIIGTSSDPMAGEPKDYRQFFDKFLHVPYPDYASRVLLWKKALEKVVGKHSETLGIRPKRLQDELDISTLAHISEGYSSGAIVRAVEQTLTQRRVECLDMRTLKEEEFLSALSRQTVTFTEDHDKLKTFTAVITGLKETRDKIRKAAEEALNADDKKGDKGGAKKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8V0</accession>
    <name>A0A8K1C8V0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8V0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932">
        <property type="entry name" value="INTERFERON ALPHA-INDUCIBLE PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932:SF18">
        <property type="entry name" value="INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="23532" checksum="D922BD2D120B0E91" modified="2022-08-03" version="1">MLTSSTEILIRQLAIHKPGSSLDYRVMTTSGNASGPATDPSAPNGPTEPNEPEEPTNLKKAAAAAAGAAGGAGFGAGLWGLAVPVVNAIGFGANGIAAGSTAASMMSAAAVANGGGVAAGSTVAVMQSIGAVGLAMPIGLGIVGAGAVVGGTIVGLKAYFSKSKPDAVPEVGGEEQQEDEDKGSGELPWSLFEWPSAAPDFVQTRFATEELARKAYKNSSASAKKLVSPDMICVEGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Y7</accession>
    <name>A0A8K1C9Y7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007013</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Y7"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19143">
        <property type="entry name" value="AKR_AKR6C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="341" mass="39026" checksum="44BAEBF1399AFD80" modified="2022-08-03" version="1">MKYRFLGDSGLLVSQFSYGSWVTFADSVTVDKAYEIMAYGYERGVNFWDTAEVYGAGAAEKVLGQVFHRGVENKLWTREDLVIATKIFTGTKEGPNARGLSRKHLVEGTKASLERLQLDYVDVIFCHRPEPFTPIEETVRSMNFIIQQGWAFYWGTSEWLSSEIIEACEIADRLGLIRPICEQPQYNLFERSRVEMDYDVLYKKYNYGLTTWSPLKFGLLTGKYANGMPEGTRLAQSEYIRSMLRGDFDEMTKQVEQLRPIAEELDCSLAQLALAWCSSNKHVSTVILGASSLKQMEENLKALDVVPKLTEEIKSRIDAIIPRVLKIATHDHWSQIRSKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA47</accession>
    <name>A0A8K1CA47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_007331</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA47"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472227" description="Multiple inositol polyphosphate phosphatase 1" evidence="14">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW59186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="157" mass="17831" checksum="48C3CB7DD8B34015" modified="2022-08-03" version="1">MWRRSAILALFLALVASVDARSGPNGKIVPPDMKGPSSKDPLFHLETSMATKTMYFDLRTDKRGVFKAFEPKRKRNEESMYTLLQIQQVVRHGGRYPTKSNMKEIQKLLAKIQKYPDIPPWLKGYKLPHDLSLEGLLSPCGSNELQEFGTRVRKAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA64</accession>
    <name>A0A8K1CA64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA64"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="15"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="605" mass="69937" checksum="439B0F5BE278BF5B" modified="2022-08-03" version="1">MGNKPSARRRSYIPHAPVCALPDEVLKVLAEYLVGVEVFALSHVNQRFYRQLSAEDVWATRVQHKTPPPNLSTKVPVLPRCWQKQAYAQSRCIVSCPWNPVVDDSKRVHEECATMLRPHLAYTVDIWFCVLPETVNGIKFVDVHCSVNHQVTVRVPTGIWCHLGWKLEEHETVYFNGREISQAQRTDMHYFAWNGELRSNFLGLTAPTYPYDTNAYFALHGVIYKLRFWPDDLYDDVTRLSRLESLSHESIRDLRGRSNEQGRPNQGTESNHFEKRRQMDDTRRRPHASAAAVDALPDEIVDVLAEYLVGVEAFALSHVNRSFYRQLSGEDVWAYRIRELTPPSWHSKRLTAMPRCWQKQAYAQSRCILSLPLDLEDKSDMNRAPGSFVTMLHPQLDYTLDVWFCVPPQLAKGAKYVNVYCSINQQLTVRIKTGVWCHLAWVLDEFETVYLNGKAIAEIQRTGMHHFTWDGELRSNFFGFTTSKHTYDLRSRFAMHGLIHSIRYWSSSYSDRVEHLALFENLDVVSGHDTRVEYDDRGRPNQGVFCSQPQEMMGVLSSLSRYKSRARQPAKQIVKTKPKRSWWQWCFCQADSTINSHRPLGAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAF1</accession>
    <name>A0A8K1CAF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipase A2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAF1"/>
    <dbReference type="OrthoDB" id="3935740at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050482">
        <property type="term" value="P:arachidonate secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.90.10">
        <property type="entry name" value="Phospholipase A2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010711">
        <property type="entry name" value="PLA2G12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036444">
        <property type="entry name" value="PLipase_A2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12824">
        <property type="entry name" value="GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12824:SF8">
        <property type="entry name" value="GXIVSPLA2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06951">
        <property type="entry name" value="PLA2G12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48619">
        <property type="entry name" value="Phospholipase A2, PLA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475672" description="Phospholipase A2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="27746" checksum="9FBA2423FDA087FB" modified="2022-08-03" version="1">MTMTMMRVLVLALTLLLTPAWLPEVDGFMNMGQQCRPFKCPSPTLKPVPKKEFVFTANGCGTTGIPIKASVDFTECCNWHDACYSVCGMKKAKCEKRLTKCMKDQCAALPDESARRECDSMAQLFSIGAQMMACPAYQQAQEEACRCVPASKVDKANRDRLAHFLEANNAPAEDVTSSALDALLAKYTGDETKMFMRLLVKYPKAIKRDASKKNFMDDILRGAEGENDLDRTKFEEDDQIEVDEHIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAM4</accession>
    <name>A0A8K1CAM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAM4"/>
    <dbReference type="OrthoDB" id="152587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="20382" checksum="82A23C1065322E94" modified="2022-08-03" version="1">MTHAFPLNILECTVVHTRKTNGHTDYGIRVQPRIGNGWDDRLFVYRRYSAFVELQRLALQHFHQDDDTPHQPGSCCCGTEACLFACFVEPVFRATEFSTTLALFFRRNSASVVTQRVVYLNAFLKMLDEAIADVPPLVLQRCEQENCKLLRLLKSFYGCVAAPRASASPVQRPQRSRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAZ6</accession>
    <name>A0A8K1CAZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAZ6"/>
    <dbReference type="OrthoDB" id="128190at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="28061" checksum="8B1D8D48E822C352" modified="2022-08-03" version="1">MDDLTRALVWKDIALRQRKLRPTTETEKEMLTSMVHGQTLVSQQLLHVLRFITLQEAHRESQLKTEMRRDIEPTEEQNRRLEELVVQVDRVFASECFQSAKLSFQDVRINDDGANGLLLDTSAGWVPPFSLDKVVDALWDTLKHMNGSRICKAIRMEMETKDGTLVGSFTLTSASTSGHIYASSTASALARRYRREDGSVSIVSTLNVHNTTARRNIVDAVIELILLQVEDSVVRKREMVEQLLLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBA5</accession>
    <name>A0A8K1CBA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBA5"/>
    <dbReference type="OrthoDB" id="68108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="378"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="464"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="466"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="563"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="719" mass="79072" checksum="3B4035EE426BAD37" modified="2022-08-03" version="1">MQSSGSFRGPTGPRFGSNHGSSNSVSSMNKGIPLTVGPPAGAHTPMNRSSSSSVPSSPTPYRDSFAADGINPSEYGIEGEGGMDWIRTGRVVRVKTTGESYRFPVDEEHLPQMEFSRHDILHLRDVMELAIDRAVRQGSVSWMENPSLAPANAKHSWKMNLEKKNCVMYRRKNDPQLSRNFLIRAKMDSSLNDVLYGVLNDNTEDERAYLAHVYRDDFLDGAVLQLFARPNEEDPHQLFAVKWTAFQSPVDSMYAIRDMLYVEYARTVVDPKGQKVVARVFQSINAKDYAIAEKDFGFARNDISWTQLYRILPGSKESKVDFSMSGSITFPAHINTPSFLANRFMSSMFTMTQSMKNAGDVKHISTHSLITERPWVPNNERSACNTCVKSFGLLRSRHHCRICAEIMCSNCTEELAIRTSRLPPSLRPDGGMISAEKFCFKCLEQGRRDRVEMLTNNPAEAYAHLSSKGSSGGHPSESSSSSYSGDFGASMRSHDSMASMGSMGSASSFSGPRGGFVQPPQIRQNRPMPGPYVGPPRSDSGYSDRPSPHPGMPSPHVGGYNQGPPPRGGYQQGPPPQAYYNQGPPSGGYNQGPPSGGYNQGPPPQPAMGGYHQGPPSGGYNRGPPPPAMGGHGNGPHVPRYDNLAPPPAPIPNSFARVEESIAEQQKLLRNLVMEGNKMMKQQQQYYQPPRPPRSTSIEIKEVDDDLNTVRSMTPDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBA7</accession>
    <name>A0A8K1CBA7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pumilio domain-containing protein NOP9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBA7"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="590"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="614"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="75012" checksum="A75702F2AE77337D" modified="2022-08-03" version="1">MAPQDERSNTESGQRSERLRPRRLEPDTLSYLKEVSETLATSSEDLGEEDVQMMLWNVLDEMAPRAASASSDRHAGELIETFLPRMSDGQLRFFLSKMEGYFSHLWTNRYSSHVLQHILSRSNVIVEKEVTGESDDSEDERLEGTPLMSEVIVNMVSEVENEWLTLMNDVSASHVLRSVLAVLVGRPLVPEKRGKKGKHRTIVFGEQSDGSTPTFEVPATFEALYQQFVRRFRGAHKQEMMNLMYDRNSGPLIAAMLKLSPEKTQTTLAEHILEWEDESRSAQVFYDFAGDAVTSHFIESFFSVAKDDFFAAVFRRCVQGKMLEFAEHSIANYVIQNAIQRVNTSDLALEVLEELGGSLWTLLSMGRAGVVWRLVEMCRRAKVHEQEIFTSVVEAVKKQESKKPEAAQKQFVPALLGLQLTTNGNNKVQLNVMGAKILAEFIQMEYAEWLKPLYTGILDLNVAQILALAMDSTGSRSLIEPIWETNDSPRAWVRKALYEKFVGHFSTLALDRLGAFSVIKCYEMLALKEKAVVAEELLQVEGKLSGSHFAQLVMNTVNLYEFRNNREKWEALHEKKDKIADMFKDMVDNEGAAGKKRKSKKQTTEASGDDKTHRRDKKKHKKSKESETTEDVDVIMGALRGSLEATKSKKKRKNKNKYADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBF4</accession>
    <name>A0A8K1CBF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trafficking protein particle complex subunit 6B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBF4"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22993" checksum="7ADD9156540497F7" modified="2022-08-03" version="1">MLNELLPEGSRNEDEGSIAKQAGKATMKDVAECCFQQLYGEIMRSMLAKYPLSTGTTGDNNEAGEAEIAKNRKEELTMKLEAMGYDVGYRFAERYGGAKDRPRMTEPLDVIKFVCKDFWILIFKKQIDKLQTNHRGVFVVQDYTFRWLSGFSSTNDQHTREMALLFLVFPCGLIRGALANLGITAIVNADVTALPGCLFNIKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBG2</accession>
    <name>A0A8K1CBG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_004804</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBG2"/>
    <dbReference type="OrthoDB" id="10265200at2759"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001289">
        <property type="term" value="P:lipid X metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="entry name" value="lpxc deacetylase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="entry name" value="lpxc deacetylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694:SF1">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW59735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="36210" checksum="1F7FE6EDB45FF8EB" modified="2022-08-03" version="1">MPSWMRTLRRAVEFAGVGLHSGQHVRVRVAPGAQEAGIRFLYGGDEESARPPIHAHVSNVDSSKSQLCTQLRAEDGSWSVSTIEHLMAALTAARITSANVEILESNGGNVVEVPILDGSAEPFAQKIAQVGVTDVLDAPLQYLRVKQPVQVVHEDKAAWLLPMPSVSGRTQQETPVLNLSVQVNFEHKGLGTRFCRFILDHDPDANLKQFLQHVAPARTFTFEEEIEWMRAHGLALGGSLENAIVFKEAQRLRDDPSAAFEVLNEEGLRFPDDEWVRHKMLDCIGDLGLLGMPLHGYFFATSPGHALSHRLVEELLRDARNYEITST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBX9</accession>
    <name>A0A8K1CBX9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBX9"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="281" mass="31410" checksum="22F8069885A93A04" modified="2022-08-03" version="1">MQTFTDNAVKAQCEREVVTSRHAIAPDNAFTIAYFFKTVKDWHPTLEINVTLNATSVVLCTRVGIMVGGGLKCLGSVQHLKHRFGDGLMFDAKLLPAPVSEVESLVLRHFDSLDARISALELSDVCRRFGESAWEEKLVETHPTGFLMASALRRDGYVLAGSFASWWLTEVRFAGVERSLSSNFARVELLERQNESCRFKLHDVAIGDRVALSRLSLGHVFGLLESSKASLAIREYSVSQTTLEQIFNIFVSQPVSCCVRRRASVRRNFVVSCQRESFISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCA4</accession>
    <name>A0A8K1CCA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000753</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Preautophagosomal structure membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCA4"/>
    <dbReference type="OrthoDB" id="2020634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="459"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="737"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="759" mass="86284" checksum="02C9F570D178997F" modified="2022-08-03" version="1">MDESLLGPKAARLPVAEEDEELWNALKDDHVDHHDDAMNVPLRGGGYAHHDPEEHEAFLSRPGRQPAAQMPSLRAHVHLPAISTLFQNVAESTKSAVASAKNRVGGVHMAGGSQSPPNTPNVRISNAPDDHGRVANVDAFLISLYNYFYHKGFWTIATVEIVSLCTGLFSVTLSSFLLGCVQWHKLLECHDEMDCKQELEHFVTCRADQPGVMHLVVAFYFTMFLFYWIFRAVQLVGTLRDAREMGNFYTQRLNIDERQLQTVTWDEVVTRVLGLINTVSIPSNLRQISSYRLQIDPVLLSTPHDFARRIMRRENYLIAFMNHSLFQGTKILPTWLHFASTTHAMFSINMECNLNICLIDQMFDADQNLSLAVMNDVQMLQKRFMIAGVINLVLTPFILLYRVIRFLSLSAQEWHTNKGLYFGSRRWSAYAQWKFREYNELPHVLEMRMARSYPLAEKYLAMFPAGLVAVVAGGVSFCASSVMAVLIGVSVMEESVLLETTLWDRQLLWYLTIFTGIFALARSFTTQSSPFLLNGDCEEAMLQISAETHHFPKEWRGHCHSYDVRDAFLTLFPYKAVLFAEECLSVILAPYILCVSLPQCARELLLFIRSHSMSIPNTGAVCRFAEFDFKRYGNDMKMESSFINFKQNHPKWVGAEEGEELMQRLGRVKEEELEKSMRLGDTMLYSSQVLSMSQQLMQSQAINTALGVNFGGVRMPLPQENEFYWLEKLHQQGQLGESVISDTSDQSHSNDLTLSSVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ8</accession>
    <name>A0A8K1CCQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ8"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071818">
        <property type="term" value="C:BAT3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000154">
        <property type="entry name" value="Large proline-rich protein BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204:SF0">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="30"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="717" mass="76314" checksum="DC52CE7B54E9E78F" modified="2022-08-03" version="1">MVTSASETVTDAVAPPAETSVSASSEPHSIGLKIRTLDQKTYPITIGSDASVLQLKEVVAQETGVLLPRQRLIFRGKVLKDDQSISTYALEDEHVLHLVVRADPPANSPSTSSADANTTSGNGAGPNARNNDEPDPTVGGPARNRVVMGATISVPEGSDVFLPFLSSMVSNLVDSMGNATNGPAGSPGVTIGDLTSRRRRETREARHLRRRQREAQANTTAGGTAPSASRSPGREGSTVAPYGGGLMLREISESRLRRLEQALANTAYDFEGLTERHLQSRDAGDAALVQQHLTRLQDLVQRLGPRLQLLPIALEQIRSLGGRGEEAPNGLVSSTIGAIDTLQALGDAASASARFTRHVFLENSPDLPVPNFHFDNRGLFRASVTIPVMNPPPGVSATQPGNPTNQSETSQSSTTGASQGTQRSGPTGMLQALYERVTAGRNRALAATSDASSTSQGSSTSTTTTAGASEASSAPSRRVTFSTMSSGPFPPIFPFSSPVNAAGWDIPGFWRRLVSDMSASSAFGVLRGDPTSLHAVMAFIASILMRGTYMPPATHPSVRSWARHFLIELRRTLTEHGIPSAILDQTPDRDQSRFIEEITRPFDPFMPELVNNFYQANGASRGDAFGRTCAEFLRTMARQFVTRMEAYVGQGSDSLPSLLEAILVTLGADARLSGFVVQSFLDWAAPASSTSTTGARRQRDESEAPPSGAAAKRRRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCX5</accession>
    <name>A0A8K1CCX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mRNA 5'-phosphatase</fullName>
            <ecNumber evidence="3">3.6.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000365</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCX5"/>
    <dbReference type="OrthoDB" id="200924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140818">
        <property type="term" value="F:mRNA 5'-triphosphate monophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07470">
        <property type="entry name" value="CYTH-like_mRNA_RTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="7">
        <location>
            <begin position="57"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="6">
        <location>
            <begin position="336"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="670" mass="75800" checksum="5893051BAFAD2A21" modified="2022-08-03" version="1">MAKRSRSVLDSMLTSLSRTNESALSAKKAEAQAAKLTAGRGHAINVEDNSVAPDAAIADFLQSMRGLIDEKGFNAQVEVELRFGQITSCLQEARCRPSQEGVDAAVLLTDEQMKGLGAKFVPGVTEAEFPNFSKGLDALLKSDAYAQHVEKQVVHNMGHSKRIIEEINPNTNEREAPHIQVKERLGSIDIFLPQCQYDCRVSISCEYPKREVEGGMGNLPAAENIRHKDRTSAVGRDLRVDITKVLEENTNQRSFEVEVELDNNVVQEWLRQPDTDGQSWKSATVTAASLWKMVKYFMPNAGQAFKRGWEFPGAGEVQNAYQLRLGVRGKFAGTMPVGFARWHIPLVKEREYYVSEKTDGVRYFLVVAGGTTVLVDRSNTAFTTSGMDLLRLVLPEGTVLDGELVMHQKEKRYVFMVFDIIATGPSASDSHVDKPFAERLRILNDFLSDEGCYAAGIRDHGISWHAILPILRKKWVPLRHISEIFRQIQRIQKRDQSYARVYNDGKRVHYTDGIIFCPNTPYVTNTHKEYLKWKWSDLITVDFMASLNDQNAVTLTCGGPRNSDIDLDQIVVLDPKDLPIIQKIVSRTPNRQAVLEFGFNADRGMWNYKCARPDKDQANYIRTVLGSLMNMAESISEEELQYRLTSPHAEQWNHHLKKMRRSLLEQQNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD60</accession>
    <name>A0A8K1CD60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD60"/>
    <dbReference type="OrthoDB" id="167432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42034" checksum="BB419BFFA30013D8" modified="2022-08-03" version="1">METPERIRAAYPQPANETAAERAKRLASKRAAKYRYFSSTDAARREQNKERQRRRREALDEETYGAIREQNRKRQKARRERMTEDDKMHRNVKQRERRARLDDVALRQLRETEKARARRRRQRTSQRGSSEHDDEDQARFDDEAYDIQTETLAARPRPSHYLPPAASLNTSSFPSSGDLPSLPPSILRSQSVPQHPSIEIAPLQFVLPPASSIQSLTLADRMAPLPQVQNVLPHASTLLNAATTPAASHALSSVSAPAPSSNTSGFSVNSSNAAPPPVSSPVSSAFNYPPSSSTSSSLLGLLLNPSPDLPPSPTPSLVSTQPLPSMSSQHTPALPSLSQLPDFLSATRDLFDGTPSGASSNGFFPSIADFASEFGETESVFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDR7</accession>
    <name>A0A8K1CDR7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDR7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="16055" checksum="8209955D4318356A" modified="2022-08-03" version="1">MHMHTASMVSPKLEGKTSFVDLAVLALVGLKETRQNYCIKWTEDVSGGEAFALVDNGQTIVFKTGGIFFITLDVLHSSTSKGFQLELLQNDETVSWVTGCQTSHGVQSFLPLTRTIKSGDTLKVLYIGNNRTNTGNTMSIIQLRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEH2</accession>
    <name>A0A8K1CEH2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEH2"/>
    <dbReference type="OrthoDB" id="193465at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="52683" checksum="2CFE34421901AAE4" modified="2022-08-03" version="1">MTLMRAVLRAAAAKRACALTPSKRLGSRAQCLPAPASRAMTSGGSGSLRHNFADSKIGIGYLQLTPEEIEAEQELLSVLPEFQQAINVLHGEDESIKQLPNTKKAAMAIANLERTADICRSAMGFRSVFLLAALRHLFLTYFMAGNYSMAKKTMLERGELMDWPVTEQERVLRLFLRMNEPDHGLEWCQKDVFTKLYPKDETVPLKWSIYELIAKTLKNGAADLHLQDPLFVKPVEILRRKKDVIAQEGGSADDSLLSHDIPYLMSQYAALSLVASDSLGKNSKDLNEQQKVCLNQAEVLWREALTWVEKTTHEGDTDELTTGVDASFEAWIQTNLGELLLRMNRNEEAMEFLGKALQTQQNQKGGNALALRRVLGKIAQGCHAVGQAVSSEGLFTSVVDSFEKEGFLSPTDQIEYARVLRAYGDLLKDWEKREGDSKAKYTKAEQLEQALAQSCAQTQCREALHPVFYLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEJ7</accession>
    <name>A0A8K1CEJ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010813</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEJ7"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000269">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000957">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3L, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="210"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="370"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="686"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="723"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW61750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="762" mass="85841" checksum="38C9A0B5071242F0" modified="2022-08-03" version="1">MMHHAWRVSRGSWRHASALERGVLRSTVSSSGSASLTRGDTLQAAIWQHVHRRLATTRAPPNAFSVIPSTLGMPRAFSTATESSGVEPAVKWPSDRAKVVYRRLKFFPRDYEVRELAVEAGLNPEEWGVASAAFRQSFMKQPELYFQDQAELEHFLQDFNHGQKKRNAFVFYPHFVEFAQTKNYMARSGEGSFTLAQITDLRLPHELYPLANAMKRRIIYHEGPTNSGKTYEALERLKQAGEDGGLYCGPLRLLALEIYERMNMDGHYTSLVTGQEKKLMPHATHVSCTVEMANINRKWDVAVIDEIQLIGDPQRGWAWTRALFGLQAKEIHVCGSGEAVELVEKFAAATGDTFELRRYERRSPLEIDAKHLQSYRHVRPGDCVVAFSRRDIFQIKRDIEVKTGQKCCIIYGQLPPETRSQQARLFNAPNNDYNILVASDAVGMGLNLNIGRMVFSTVKKYNGAGAGMTDISPSLAKQIAGRAGRFGSDYSGGGVATTLSQEDLEYLKDSYHAPITPLKSAGLFPSSEQMEEFAKQLPGVTDLGDLLDKYVTLARLDGDYFMCNHVDMKDAAGLLRDIDIKLSDRFTFCQAPANLRNPLARRVFVDYATAHAKDESVKLDIYLPRYAPQTAETLRDVEIKAQIIDLYLWLSFRFETTFVEHELALELKTKALELVEQGLVNTTYHSKKAKREMRSSSGRDRRSGERGGDHARYVRGTAALEEAALGQDNDDERQEPVEEGSFGQRVHERILRGLRKTRSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEY1</accession>
    <name>A0A8K1CEY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C3HC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEY1"/>
    <dbReference type="OrthoDB" id="614844at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="8">
        <location>
            <begin position="242"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="44075" checksum="C57A3D9B0A3E87F2" modified="2022-08-03" version="1">MERMEDAVERTLARWRDVTTPLDHKAIDQDALMIASSSLTALVTSPRAKKAGSSSPTDFTSKQCRAWSHADFLQRLATYGIATWFAKPKAISPLVCARFGWVNTASDMLQCAHCEEYLCCAIDDKLSKDGVKAVAERFAGQLATSHADMCPWKSNPSPESFTVLPILSPHQVSDDITTRMEKLLKSLKPQSLLSSFDIAPEAVGKVLDAVDKEVVPDLMTLEGLVRARFPTHSVDTAVVLNAVLLTVFGWQLQSESGALSCEYCNRSLLLPTDKADTEDDEKETEGPPAKRQKTASSPSRPVVNPLAEHRWFCPWVIPQCRNASEQGRMRELLGLLADEQLPLSDQKLGEFVQLPGWTQYAQALKHLKHNAAASAPHPDSSTPEDALARIQSILGLPEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF18</accession>
    <name>A0A8K1CF18_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chorein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445152at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039782">
        <property type="entry name" value="VPS13B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517:SF0">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="3">
        <location>
            <begin position="9"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2025" mass="224815" checksum="78DD4134091DE07D" modified="2022-08-03" version="1">MLDILSSPLRGYIAQNLQFYLSKYIEGIQLEGLGLFGGDLVLNDLEIKRHVLAESLEIPSSFDFSRGFIRELRIHIPWTQLLSQPIEVKLYTVELILTARDPSRRHSVDSAMAARHSARTRSIESASSKEASEIENPKSGWLRDTLQKILANVTIQVNNLVMKYEQDDVVLSVALGVLDCYSVSETRGWVRSFVDPQGSTRAISRVIEAKDLTIFLDRYTSDRSQSDPSASEIRRRVVGYEVPVLSRTSLSIRGRIQLKPKSDKDDEPKMPLSATDSTASYEPSNYCDPFFSYSCSRNNVIPMLEVDAFIGELSFSLSDRQLQMISEMTRRPSTVVYDEELDEANYQTVPVVASPSESAPENPEPMGKQKQSWFGWAMKTLGGPENGDEDELESELLAATKRALQRQQPVKSPALVDGSVVDKPLSWFVSCFRVCISSTSLTLRKHEEEKADDLGEDTTQAQEEEYVPVANLGLVRVSVKAKKSRVSRPAVPVFVLTLAYSAMECITVRGEKEWTDIVCEVESVEFLRVGMVEEKPPLIRWGFQDLSDFSDCVGHPYFAASFFVEMTCQVTKVDVFLTRLSLNHVTKIGSYRVAEGTSSGSKTNAKRATSAKQVWNVRCGIQLDRFATTLQVPWDIPNRSKQNIGDFKGTGGFGDLVSLWFDAEEKEEEVKYHRVLEVTSAPRFLQLKEALVSDKWEMRWRSPLSGEKHQQIRLHVSALLAASIRIRSLLDTSAFQRLSVQCSVPRVGVAVAFAEDSKTSYDVLSAELKESTLAVTSYAGNGETRALVQSSLQVYLENMVQLLTVSIIPRLDIHANVRTSRDSSEISLVLGNADVFLSQTAILVLYSIPDILSQRRSLLAHGGGDLSKVRIEFVNSSGRDVWYRQEGTAECLLLERGKKDAYSWLTLDRPAYNRVQFALSTGTDSSPALTDLSWCDPCRIQENCVTGRYFKDHGFMWIAVETIGMKTVVSLRGGVSISNFTDVDIDLEVTTKNQPSLLLSVSPCQKTPNGLTKKLASDQNAVGLMLDQLEDSKILLSPSKNLTLDISGLPQEFDLAPSDGTVADQTRRRLISFESSQGQRHVWAEAVRVESRLAILPTDFDNEQPRFGVRYTWVQVNFHPAICIQNLVDDSLRVELSTQDGDSYCCVVQPNELHFSSEINAAQVRALIISSNNTGVQETELADLGSRRRYHTEDFVIDVDPVGVKPYTSLTIRRPLCVINNSQSVIFVTTRKSSQDENKDQIKLSGGSETTVAHTVEEKNAMILVALGAPESSSEEDGIAWSPEFTLSWESSTQCCCVVHKSVPASREGLPFVVKLIRENGEAKIIISPLVILHNETGYQLKYASTDGGDAFIGPNYDTAKIDHDRSLDVTVCFPVPTRRRKISIGGLTSWLSSTITLSAFSTRAECIGANHYMEYDWSLQTQPSRSTNKNVEASPAKLESWLDSSAVERYIGAPSSDQSATRFQIGHPDFGWSNLLWQVPGIQFARFSNEVDSGSPVFLVATIYRAGSWQISVTCLDEPGSIQTWDPSIIPSYFQNVEVKIAPAVVQIEDELIVHVQVFMRPVLDGIAGLVATRIRAMPPRKSMPVLWMESLREKLRITSQQRVFIDRLDISTIELTITARISLPVLSSFDGTPLRFGQRSIRQVFTFSDQLYKDLAAEYVADVIVRSPMLLMSLNIFGNPAGFFRHVGTGMRDLFEIPFAAASRDGFNPWILTKGVFGGIASLIGHTSAAALSSIAGFSYSISRTVDHITLTPEQLRKKHYVRPAHLTTAIAGGLGSLGSSVVGAATGIVSTPLAMYQEKREQGLRAGVSGVVGGLGMGLVGIVARPMGGVAALVAMASDGILYGTGFGGIDAMDESDREAMFDARPNELLRFKLKVLRDPSVGELIVAHGVWMNPDVSLLLPGIDQEELQTLSEEEKSDERVSELFTTQAWRDQSAVVIIVAAMRDTVFVIALFKEHLRHVIVSKTSLAHFQAIEESLTEPSRLDLGVQHNEHVHWYNFRLFTSQRRELSRQLRQWMLEGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFD4</accession>
    <name>A0A8K1CFD4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFD4"/>
    <dbReference type="OrthoDB" id="73614at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="17807" checksum="35C8468149192BBB" modified="2022-08-03" version="1">MDHIKVIIGQGKAETTATTSGENLTAMCPTLTKTQRMVGFAACFCIGYLISFASTFALIAGDGNGTRFGITYSVGNIVALCGSGFLVGPKQQVKLMMKPVRRVAAIIYLSMIIVVLAVAIAVPDLGGLVLFLVFVQFVAAVWYSASYIPYGRKILKGILKKTCGVSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFH5</accession>
    <name>A0A8K1CFH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFH5"/>
    <dbReference type="OrthoDB" id="161578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="226" mass="25625" checksum="E86110E66B06E0C8" modified="2022-08-03" version="1">MGPTALCEHCSKKLTLFTKRRRCRHCRAVVCRGCYEPHAVARHPNTAALSSGVDDDDVHFTSPTNAEEESGRGSSFREFQDESTADLLDGADDGEGVDGEENDDEDEEDGGEEEMMMGLQYGRRASYEEEETQFREFVQIQHAVEKWTRKELDIKRQERSSKQLGAIYVTKPVPNLRSVREYQLRELFGITYGVFVTLIVWCIGGIGLLVYLHFRTRLASTLAYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFP0</accession>
    <name>A0A8K1CFP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-coumarate--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005234</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFP0"/>
    <dbReference type="OrthoDB" id="143058at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="578"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="745"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="5">
        <location>
            <begin position="434"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="91769" checksum="FCD1A83F2580358F" modified="2022-08-03" version="1">MIFSSPHGTLHSEPNRVVWDDLETQAQTQPFAPAFVCGLTHRVLSFGDVHSHAKAIVAGLHADGIRKGETVILLSINCVEFPVIFMALNRLQAICSPASPMGTVDETVYQINATKPVAIIVHPVLLDLALASAKATGIPTSRIYTIQTIEHPAKLPSIQALVENPRKFPDIPTIDPNAIVALPFSSGTTGLPKGVQLSAKMLYLCVFQGSYTEEDNAYYQGLLPFFHILAMASFQFTIMRGFALVVLPKFDPATFLGTIEKYRIKKVSAAPPIVLFLAHHPIVDKYDLSSVRVVASGGAPLGKEVSEMVMQRLGAKVQQGYGMTEFAGPVTMPEIDNYRHGSVGRIVPNVEMQVRSLKTDELLGVNQRGELLFRTPQTMAGYLNDPEATKATILPDGFLRTGDVGYIDEDGFVFIVDRVKSLIKYKGHQVAPAELEDIINRHPMVVDACCIRGKDKGNGEEIPKAVVVLKPDVAGQVTEEDIMEFVASKVAPYKRVREVEFVDEVPKTLSGKILRPTPCLVINILIECLPLRPISEGLTTSHNFWIRSSIGLHFIAFTSLELYRLFVPSIPSTLRQIVIMSFIVGTGTTITEYLCALWLGYPVPLCAVLTAPMFMALMVGCVAAAWGKFLKENKVVFLELQHFQTVISIIFSLAFIDPASNYAFTEQQLLLESLKEKDRVEYIDSVLKLLHMIEYLVLIVFTELIIPFVYSVYLYSTFHLPNHAYHTQLRDLTEDEIRRVIGNNLVYATLELLSLVILQIHLYRKFHISAAHQLAYVLERQWISVQLKLCSWFIFIIQFSVDHFGADYSFRFNWLKKSRPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFU9</accession>
    <name>A0A8K1CFU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="1013"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="1303"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="259"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="440"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="638"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1466" mass="168087" checksum="CCD7DB73A19B3449" modified="2022-08-03" version="1">MWSTSYSTNTAPIMANSSIGVGGSDSAARDSGGGEMATPDARASSARNTRLTVYPPVPMDGPRLTLVLPRTGDLRLRPMLSNVFEQQLAIHCNAEYQHVYRKFMVVRKFLVMAVDGNLYTHHLRSILRLEHLPNGTLLPPPASMAPMDVVKVLDLVQCYTFDSVESRTVVPTVRWELVRVRWRSGRETWIPRELMDTQDPKLLQEFYVNSANSWAFRDRIFPESLSAYLTEAELWRHHPDFKRFVRQLELFQRQRATLEPATAPVPAPASTSASLASTMGSASSQLQRQSEPSPQAQHVPTATLDEDSMDQTYEPDEVLTSEVGSAVEGDRRKRMRKRRRTEDGTSQPDALELPQTTAVTIADDDDAKQRKQEKKQRKREEQLEKERLEQEQRLKEKKERRKQRKRERKEQERLERERIEKEHKEQAKREKKERKAKARREREERERQEKEEQEKTERKEREKRDRKERERKEREDEEKREKKERERKQRKKREKEEQIEQERREREEQERRDRAKREQKEREKEEREKSVQEKENKHTSHSVVDSAKSHKRKRRLKVSLVDSSEEDSEIEEILSSSQRHSQPIGSSVGTEKAKRFKRLRRPGSDDDDDDDDNVTLVEIASSQPSQLENSEAATEVVIDDGEDDDAGDVGELEIGGDEYDEDPDANSVVGLGEISCVCGAQGIDRYTGRWLRCCREDCDAWEHAECVGMLDEELEDFVTDSYVCSRCDPVAFRARYARARSRLVDWMFQCSQHKNQTQLLHLLTTEQSTSAASDWRCKSLQNRTLLMQVARDGLLRVVKTLLTDHHANVYGLDSHSRTVLHHAAFGESLAVARFLLAQYPALMTNADLSGVMPLHLMIRSPRLNELCVAMIETNRAISVTSDFDGNMPIHCACHVVNASTVAIVRMIMNFQPLAPFEQSPEGEWPLLLLCQAISKQLSSDPNADRTQHAAAAEHMLAIVRMLLEVDPLGSFLNVRDKRGWTAVHYIAYHGHHELLTRFMQLPCLEYDAITFDSGETALHLVARVNSASAVNALLVNDLADVMAVDAAGWIPILRATEPMCLREFLHYDLQSQLNKANTVAQRFGQREAIRKWLRQLLHDPTCFDIVNDWLQHHLAVMDEIDELARLNRSLVRVDNKLEYLARFVFPSVRARAPRTLQTKPFQITLDGGLGCCWQQFVSQTQDFAPDVFRSSIAHFRFVLTRGELLRVDNVLLVLVRLISGLVHADTGILDRNSNDTLEPRTHASITRRTLIEFCVLGQLVAYLVLNKVVISDVFEFSTTFLECVLYGKAGRNVSRSFVACALSFASGFGHVLPSTLSLLRVGELRLLLHGAETSGWNALQVNWASAVDWVGFGVDTTKMQSWWTRLLQELVPEERVLLLLFVNETFRQTRRSLFPSGDYEKDSPRMQIKMYRHHKDSEDGAQGGEDLPLPKAMDQTLTLPMYASYEAFHAAMLRAVRDMDIMARVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGQ7</accession>
    <name>A0A8K1CGQ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGQ7"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF22">
        <property type="entry name" value="OS02G0130600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="37314" checksum="5E7EBED6F907A258" modified="2022-08-03" version="1">MDIQGIHESAVPWETIVVTVEIVGALAASLWMMHHRVARDMMILGGDPHTVVALSPLAQPSSYCSLGLLLAYRALATVFYVVVQLYDIYRTSWRCLAFYTSWNFIAQGSYFACAALRTRKLWKRSMDPQGEYTALRDESMSFLRTNTFVGATRRSWLRLDLVLDVCLATSLLIGVVVWTILYPYAQDIGHPELILNGVSYCQHVINIVLLQLDFVSTRHTVVLDALPFLIAWPTIYCVFTWIVHGTIKRGFWPYPFLKLDTPWAPLWYGGLLFAHLVAFLVMLYLSKVKTAYRERSLRQEDYGNDSESGLESTPEPLSPRASEPHGHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIK5</accession>
    <name>A0A8K1CIK5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIK5"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42203" checksum="674A8512DB284EF5" modified="2022-08-03" version="1">MSKDLSTPHDDNLRSPANNNYHNQEKDVAVLVGKEYDEVEQGPRRKRFFCWRLTKKQWILSLVGLILGILLVVFLIIWFAVIPAVFQKKLDAVELSLSHFDLLKLESDPSTNTAGIELQIHVKTDGSVNAVMDSTTATLYYKDRPFTTLTLPEQNIRKDTPEYDITIKDTAVFSDVAVFRELSRDVVINKEVEIRAKASPTIHAFGLSGKDLDLDRTITARGIWSFNDPAAVINEMKVTGCPVDEITMAVNITIDNASQIGLNGIGTLNMTLYYEQDKLGYAVMRNGERGMPRGPIDYIYDVHVSREESPFKIFKNMLIGILSGKSQMYITGEHEGATKAYLLGDALKAYNQSILYTDGLEKVTQDPDCDLTKIALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIM6</accession>
    <name>A0A8K1CIM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005465</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIM6"/>
    <dbReference type="OrthoDB" id="1847590at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="29859" checksum="C7FAF7273DED44AE" modified="2022-08-03" version="1">MPQHEFMDMHKKRHGVRMDAAERKRKKEAREVHRRSQFAQKVHGLRAKLYNQKRFKEKAAMKKTLALHQERTNKHGNDDNIPDGAVPSYLLDREGVSRAKVLSNTVKQKRKEKAGKWDVPIPKVKPIADDEMFKVLRSGKRRNKAWKRMITKATFVGENFTRKPPKYERFIRPSAMRFKKAHVTHPELKTTFQLDIIGVKKNPQSALYTQLGVITKGTIIEVNVSELGLVTTSGKVVWGKYAQVTNVPENDGCINAVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJB2</accession>
    <name>A0A8K1CJB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002717</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJB2"/>
    <dbReference type="OrthoDB" id="3142434at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="184"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="393"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="479"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="524"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="764"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="887" mass="98815" checksum="71C0AAB8E4F24E05" modified="2022-08-03" version="1">MKFAYEFRHLCGTVYSQGNVVFTPDGNSILSPVGNRITQFDLINHTSTTFSFEGRKNVEQLAVSHDSRLLVAVDSDGRCLLINLRKRVVLYRFNFKKAVRALSFSPDDRYLAVTHGNKVQVWHTPGLRREFAPFVLHRTYGGHYADILTLTWSHDSKFFVTGAEDLSARVWSVDSYPDFQPVVLAGHRDFVVGAFFTADDQEIVTVGRDGAAYLWGFHLPESETSDDDESSENDDEDGDVKMIKAKTTLPAIARAIKWYTKKKQVFKMDYARVLCATFHAQAELLVVGFDNGTFGIYQLPELHNIHTLSITQNEIETVAINASGDWLAFASKKLGQLLVWEWRSETYVLKQQGHYFDLNVVDYSPDGRIIATGADDAKLKLWDTTSGFCYVTFNEHQAPVTGVKFTPNGQAVVSASLDGTVRAFDLNRYKNFRVMTTPEPVQFISLALDLSGQIVCAGTLDPFNIYVWSLQTGRLTDVLSGHTGPVTSLAFSPSVSSEPVLASGSWDHTVRLWNVYQNKSLIEPLAHSTDVLAVAFRPDGKQLCSATLNGHLNIWEVKDGELLSTIDGMRDIAGGRKSTDKITAQNNTISKHFTSVCYSADGTCVLAGGRSKFICIYETSQQILLKKFQLSHNRSLEGVLDYLNSKDLTQSGLTKNELQSYADALIPSRGRNKSAGEDLVGASRSVDPGSRRKNLEVLSKAVMFSPTGRSWAAATTEGLLIYALDETLTFDPFDLDEEITSDNIKRTLKKQEFAKALLMSLHLNEEELIQRCVEGIPVANIPLVAQSLKDTYLKRLMELLAKQIDASPHLEFYLQWSLAILNTHGSKLRDEPSGFLSTLRALQKSVARHLHDLAKICDDNQFTLSYLQNLSRLRSRASTTSAMAIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJD8</accession>
    <name>A0A8K1CJD8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJD8"/>
    <dbReference type="OrthoDB" id="151467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47210" checksum="92890968E234638B" modified="2022-08-03" version="1">MDSRKQPAARREAAAAASDDEEEKQQHDQQQQQAASPKRRDDGERAVFGRLELDGEPDQINYRSTTVAPAFGMEPFGARPLMHGTGLPGMTGMLGMPAPVNTKKTTAKKAEAAPSIATRSDKTNYASVAPRELPPPPFRLELHTHFHVKNEAIQRLCSLVGWKLCELDTDFVFKADKCKWKVDYRRNGGAQRVNLNILIFKSGKEYVVEAQRREGDITASMHLYSELKNVFKRHQMLADKEKQQVAGVKRPAPKALPKIPLTPANVRDGVSALKGLLESKYADIQMQGVLGAISLSTEETARSGMASIVPQLVVLGQSKNVNVAKLVRVALSRLCDHPECRQAFIESDGWQFIVQCAAGGADVNPEVQRESLHVVECLCPLYSDELAKVEGANKVLELIQDWQNIDDPRLKRHACNAHQALKEAGAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKF4</accession>
    <name>A0A8K1CKF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKF4"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052920">
        <property type="entry name" value="DNA-binding_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358">
        <property type="entry name" value="ALPHA/BETA-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358:SF4">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="92"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="58390" checksum="53EBCFF25D28A834" modified="2022-08-03" version="1">MQRASMDDSTTAQERQSMWSMIKQGYEGLVMTVIRPMRAIYSTEELGPARLLLGDTVTQRHDLQLKNPAGYTLECSWWKPKPANKAAKLPCIVVLHGNSSCRLGCLEIVSFAIPAGFSVFALDFSGSGLSQGKYVSLGYHEQTDIATVVKYLRESGETSHICLWGRSMGAVASLLYAQNDLEINAMVLDSPFSSLPQLALELVEDGKVGVPKIAVKLVMRLIRRDIKRRAKFDMFKLKPILKINKCTTPAFFVIGLQDELVGPHHVEALHKHHNGPHELFQFPGGHNSPRPINFFIEALQFLRVMVGLLPLPSDVFNMDATSPTSPKRRSPKPVKVYKNPLKPGVSVEAIHQMSIKELKEAAASVGYGDVSCVEKKDLVDLVLKLHQRHIRSKQQAKQYSEDDISLPETLPQAAVAATVPPPAPSSPTQKTAAARNATAPVERANSNHPASPHSPSKAPRRHSDSNMDLPPTATTSTSPTPDASTTQDNTASKPFPVIKTTSSSILSDIELSRELSHGGVASDSDEHDDGAAKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKN9</accession>
    <name>A0A8K1CKN9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Radial spoke head protein 9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011376</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell projection</location>
            <location evidence="8">Kinocilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the flagellar radial spoke RSP9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKN9"/>
    <dbReference type="OrthoDB" id="10258956at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001534">
        <property type="term" value="C:radial spoke"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006802">
        <property type="entry name" value="Radial_spoke"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055316">
        <property type="entry name" value="RSP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22069">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22069:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04712">
        <property type="entry name" value="Radial_spoke"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30677" checksum="ACBD6274691A2C0A" modified="2022-08-03" version="1">MELEHLDVVSRCIGQTLNPQERSNLEIGLLQRKTTESLASIRFWGRLHGETNDYLIAVGVLSARDYPKKKFYFCTNSSPELQQFPELTKHKADAAAKLTTRLKGDPTLVLTASGEDQSQNPEDGDSPFTELDRLAYIVDQIDRAVSIVPLEAYVVSPMRQVVANPAFHGLKWEQAIQPYNYFHFREPELPEKVKALHNSEGLVRAGDFLDPLIQDLDGSWSITRDNTGRYVTLRNFIYPGSFFFHEPESHHYGAVYFGDGRKNPDIAFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKU3</accession>
    <name>A0A8K1CKU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011385</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKU3"/>
    <dbReference type="OrthoDB" id="268593at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000156">
        <property type="entry name" value="MIP06385p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058256">
        <property type="entry name" value="WLGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26605">
        <property type="entry name" value="WLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462513" description="Peptidase S1 domain-containing protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="11">
        <location>
            <begin position="47"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="927" mass="103457" checksum="55254634838BECDB" modified="2022-08-03" version="1">MKIAAVVAAAAVAVSAVAAEPISYAEYQTGISEFNWEAGNSAIKPLILGGTEVPVGTSQYIAGMRSTAAGRSFCGGSLIHPKWILTAAHCESSIQYVNVGTHFLSGTTDGTPVKVIRKIHHPSYRSASSGFDYLLLELESEVSYPPVKLAKADGTDEPVGTVSTTLGWGTTSSGGSQSNVLLQVDVNIVSNDDCKKVLSVTDTMICAGGELNKDSCQGDSGGPLVVHQNGTDVLVGVVSWGRGCGQLGYPGVYARVSAGRAFIDHALVAFMLCFRRRALQPPKSQAAVRPRSQSLRLSAVQPLSRRLSVKYLVNARRHTHHSGQSDLKQPSEAVKGQPTTRFDTLLFEFTSIQGAYHCYYNAFFDLPKLVFQTTSLITYLDKGFPLPLIYFFAALLLINWLISFYRFQRRAMDSKLVVTRLFYLFDLFFAVFAPMVVLAYAYYQFKMDRDEFDLRESALSPGSYDRIARLFADPVQVDVFRDGFANTQLTKTSYLIAKLCLNTLVLYKWKHIIVYLIQQQHLEAKQRQVGLKQPRASQIRLHGPQRKRHRFAGTVLFFSGIAFVVSYTIISITSSQRNCAPFQQCRVMSFEWHLGANDTACPCIVYIDRDLMPTTFDQWMNPIDVTHELAEVARPGRLETVQIINRAVPTLPSELENCRSLQELILIYTKTQELPVWVKSFKHMHHLHVESNFLHYPLHTLPLDLFSEMKQLRFMRFGGPAALQEFPSLQGLRQLTTFVLSLPHSLTALPAFDGLERLATLFVADATHVPRLPSLQPLKNLKSFSLLRRNAVCCNGFVTGRCDLTDFQCKPRVDEPVVECVSERIDPQDLQLINSVNHFLCSVNLTSDVSDSEPRFESTDTLCGGVKYRQCAYNGRTGICYNGRMQVLHCDIFGEYEKLRRLEIARGIGPPCDPVVEKWLGCKVTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL38</accession>
    <name>A0A8K1CL38_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL38"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="163" mass="18487" checksum="4109AE748FE955C5" modified="2022-08-03" version="1">MLLHLDATRIVNLKKGLSCPKCQTIMRSRSCLKKLPRQLNNTRKPVVTCPQCDEDVDARAEESPVNEALRQTIQTLYHLCESPQPVPAPSDGKSTKRRGQKRTRMIEDISTSEEGRGRRQRDAGYPLRSRSIATVEQEEQSQSEETETEEEEDSKPVRFCSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD5</accession>
    <name>A0A8K1CLD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab3 GTPase-activating protein catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rab3-GAP catalytic subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD5"/>
    <dbReference type="OrthoDB" id="17346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045700">
        <property type="entry name" value="Rab3GAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026147">
        <property type="entry name" value="Rab3GAP1_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21422">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21422:SF9">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13890">
        <property type="entry name" value="Rab3-GTPase_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab3GAP catalytic subunit conserved" evidence="7">
        <location>
            <begin position="764"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1190" mass="131597" checksum="F7AFDCBF75C27AD3" modified="2022-08-03" version="1">MQVEEDPSSQFVDFTNATALEQFASDVEQTLIAWQLVSKGHAASLRASNATSTSENDAVRTFTRVLEWTQSHGKSTTTVNYAVTLFVGREEAAEAPEPAKKTRRASKTQQWQEGREHFTPTMLAVADATREMALWKTQKENLSDGWESNDMGAEIIAQNVRKWFGVEEFLFLSRTSLKSDRQRQQKAAKQRVNQPTTTGERSRREKDDFTDNSALDTRPGAFCDGSMDPHEANMVLSAVHLALNSCNCTIPAFVPVFDPARGTWLGSATPGSTGNVSIVFETDSVPEMNSNQSCISGLMDFFQTKLQLPPHIEEQCRLSSGDSENLSIGMWVSAAFHYKWRRDEDPREIEKVGADWRYVRKTSVSSIPTRVMESVFGKDHTSYWGPATSPLQSLRLVTMWPSLREGTYVDNAVHSTLDPLTAPQWILHAQFDESHTSHHARNVHDPSRKPTMHLSRLVANLVHAYSKSRELSRDTLVSELAPTIPVPSASNSSSSPSTPPASGDEATYLSGSKIRTDAIPAARAAVVLGNAIGTITSTLVSAATWKGTDIEEIRRVVSDLFDNDGGSMVTGGTYQAAVDSVPSSVKHGAPVGELVSILACRMGQLHGLHSMSLLWVEFVKSLRDRWFLQQLLPRLSTSDTTGDEHNGTEPVFDMFMQESTSSSLPRPDFHQCLLHQKLQLLNCCILRQAELSRRESAGIEAASPLRRSSVASPAKTKMADITAFSIDEDEDATVKDESPSDDEFFDSVEQDEQAPGTAISSGTTPEGVKRTIPGMFCLKTNSMMMEPVTQAAVPLTEDVAAQQQELLSRLGVTGESAMLRQQMQSAALVSDMQAFKAANPGACLADFVRWYSPKDWIPFDSSNTADLPAGGKDLWWFENKGMLSERMRTPPSSSESTTSQHLWYQMWQNSVPTPVVKQKRLFDPVGESEKLYHYLETIAPHEMFHQMLAAAISSCYVALEQSVLPFPSTRIPLIRAALGQLRTVCDRAITLLDDAFAASQVAVPVSREKKEEEQARMKGQLQVAFEMALDACWKVVQVFEECEMLASEASSLIQLLSDPDASDVSSEFLQLVNALLLTNRSGKLPTDASSSDVLILLQNEGMRNRLASLVLHNPSSRDPTQREYVLRCICPRPYYEDPLHGKHGFDGNESDAESTLLDLVDESPVVVNRMYASFTRQTVRFALTLSESEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLT3</accession>
    <name>A0A8K1CLT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007940</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLT3"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="11">
        <location>
            <begin position="33"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="12">
        <location>
            <begin position="529"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="10">
        <location>
            <begin position="650"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="90246" checksum="4B048B160CE80E0E" modified="2022-08-03" version="1">MVVQNVRTALDAPALEKYIHAALGDFHGPLAEIAQFQHGQSNPTYLLTMATSHAKWVLRKKPHGKILPSAHAVEREYRVLKALQYTEVPLPKPILLCEDSSVIGTPFYLMEYVEGRIFEDPALPGVRPLHRYAMYSAVCDALAKLHAVDIKEVGLEDFGRSDHYSQRVVARWTKQVEAGSPVFKKAGVAENPQMDKLRQWLQANADAAEAETAGRPVLVHGDFRIDNVIFHPTEPRVLAILDWELCTVGNGFADVATLACTYRIPSDMGDIKMKIPGLKGLKKSFEDLGIPSEYEFLTGYCRRAKRFPLKPETWTFFLGVVFFRFAAIAHGVYARSLQGNASSAHAHDAKRAMDAILSYSNELTGTSAKSIYPEPKLDHILPFPIRPHALEMYKTMLKFCEERVFPAEHLHFKEIADARAKGREWKDTPEITEVLKAEARELGLWNLFLPQGTIPASEGNPAYKYGSDLTNLEYGLMCEITGRSILLAPEVFNCAAPDTGNMEVLHRFGTPKQNHKWLKPLLEGEIRSCFAMTEKLVASSDATNIETEFVRDERTGEYVINGHKFYISGAGDPRCKIAIVMGKVVDKRHIGKKTDPFRQQSMILVPMDTPGVEVIRPMEVFGYDDAPHGHMEMVFKDVRVPFENIIFGEGRGFEIAQARLGPGRIHHCMRAIGVAERSLELMVKRAKTRTAFRQLLAENHLVRSQIAESRLELDSARLLTLQAAHQMDTKGNKVAQQSIAMIKIAAPRVALKVIDRAIQIHGAAGVSQDFVLAYLYAGMRTLRLADGPDEVHMRTIAKLELTHCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMR8</accession>
    <name>A0A8K1CMR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMR8"/>
    <dbReference type="OrthoDB" id="10659547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="246" mass="28604" checksum="D4A1AF3D1A1840C1" modified="2022-08-03" version="1">MKMPTWPSSVYDYDAQTIADEDAAEVDLRWGGWIRCRYCNGRKQKAHEAFSEEGWEAHKASSSHQRAKSEFDASVEPSGAAKTSKDDTEAVNDPSRFHEYADFSAAMADIIRKDTKFLAQEKAKHDKDAREEHRIKELLRQTTLLVLEQQEDMEHLRSQVTDLQHSMVHLQNELRTARSQSMWTVMQQPMDLRKRSFQDVCTERTVRQRIETPVVVEIISDDDSDEDQSTDLFDELNMFDRGTRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMS5</accession>
    <name>A0A8K1CMS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMS5"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000116">
        <property type="entry name" value="Leucine-rich repeat-containing protein 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="62"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="630"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="633"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="726" mass="79917" checksum="B3AEEDD999B811AE" modified="2022-08-03" version="1">MDKDEKKWECVDLVKIDLSHNAIPSISDEIGALATVSSIKLCQNTLTSLPEGLFELTALTYLDLSHNQLQGKLSEGFGALVNLKELGLAANKLQTLPDAIGNLSSLEVLRIEENALIQLPARIGQLRRLHTLTAHTNQLAALPTSFSELRSLQTLDLRKNRLDTMSGQLSTLQSLKFLDLRQNKIVVFPNLPQSAALDQVFLGYNALAQIDEDSILRAKDSMTVLELRDNKLSLLPANIACLYRLKTLDLSNNDLSDLPPGLGYLKHLNHLVIDGNPLRAIRRSVLSAGCEAVKKYLRTRGGPPSGVDVLEEEIDELQVQRERERLVKAASSAIGTRAAASASTPVRNQHVYREAASSGTLDLTDQVLQSIPREVSGDGAHNFSSTLLHLNLSKNHLTRLPEQISGLVSLMSLTVEENQLQTVDPSIATLPRLQLLRLRKNQLTTNAVNEFLANEESSLGSCIKELDLRNNQLTQMPSQLRQLASMETLLLSFNKIESLDGFPWHELGKVSVVSISDNRLKSLGQIYHTPMLASLSFENNNLTQVPCELGLCPHLRAIYMNANPQKTVRGGVMAKGSLEIIMYLKNKLPINSVLTPPTSWKESKAMAVQDAIFPVKSNIKNRPKLNMYAATADDPESVEEEDEAEVVPTLSRISSHRQHEIRSPQDTGGDSKGSSTDLATIDGQIASLEQQLDNQSGLSAAKRYALKKELALLRSSRIREARKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMV4</accession>
    <name>A0A8K1CMV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysosomal Pro-X carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004179</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMV4"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000007">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF120">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="63246" checksum="BCC3D27B5A5A153F" modified="2022-08-03" version="1">MTASELLPMLRPHDGAIQRRHEGFFKRLPLICAVVGALLAPIVLFVDFHSAKNVNTNDNVKNVSINNINNFTPLRVEGLSDAVTSAYELNPDGTPNLLKECKELYFTQMLDHFIANSPTYEERYFVCDKYSRKDGVIFFYVGNEADVELYLNNTGLMWENAEEFGAMLVFAEHRYFGKSVPFGSEVRQHMQYLSTEQALADYAVLIEAIKEEYKLDVPVVGFGGSYGGMLGSWFRMKYPHILDGVIAASAPILSYIGDEKAVDMESFARITTFDASPEAGSSEQCVPNVRRSWQVIRELGKTDDGRKDIATAFSLCDTEKLDSEEDVESLIQWIKSAFDYLAMGNYPYPSPYIMNGKSVLPPYPVRVACDHLKFTYAESDHMGLLEALRDGVGVYYNSTFDAKCFQTSPPSNESAADSNFWDYIYCSESYQPTSLDGEKDMFWPVPWNLTADAENCKKEWNITLRPHWAVTQYGGRKALKAASNIVLSNGDYDPWSGTGVLEDFSDSVVYVPVEGGAHHLDLFFSNDMDPPAVKEARATELKHIKKWVREYYDQIKKRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMX0</accession>
    <name>A0A8K1CMX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000015">
        <property type="protein sequence ID" value="TMW66576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMX0"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422393" description="Glycine-rich protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16613" checksum="A07C8D8F1D0537CE" modified="2022-08-03" version="1">MKYSIALAASLAALVSTIEPISANSVAISSDAKLPSPTEALDTVKNIDLPKGITLSNKKESDITDNQIAIANDKQDHQDHQEWYGRGLGWGVGGWGGLGWGGWGRWGGWGGFGPYRFGYSCGGLGGWAYPLGYWNAFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNN0</accession>
    <name>A0A8K1CNN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="15">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_004189</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="15"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNN0"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000069">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424008" description="NADH-cytochrome b5 reductase" evidence="16">
        <location>
            <begin position="30"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="46"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW66424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="293" mass="32713" checksum="9E011B33F2FAC5C9" modified="2022-08-03" version="1">MWTILRFPRAHMTPSLMMGLASFAVVGSASFSAAQCEEKKTALSAKEFRAFKVRKVETLSHNTKRITFDLPGDDYEMGITTAGLLVAKANIDGKPIVRPYTPTNLNDELGFLELVVKGYPQGLLSKHIVELKEGDSLEMKGPFLKFKYEANRYKKLGLIAGGSGITPMLQLIKQICRNPADKTEIVLIFGNQTEEDILLRDELDALQYLYPQLKVHHVLSNPSESWTGLKGFVSKEMLEEFIPGPSDDHLVCVCGPPPMMYHISGDKAKDKSQGQLQGLLKELNYTSKQVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP10</accession>
    <name>A0A8K1CP10_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_003717</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP10"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000713">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000537">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053858">
        <property type="entry name" value="Arb2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22749">
        <property type="entry name" value="Arb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="267"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="436"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="548"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="818"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW65952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="884" mass="99882" checksum="59255E6B17E8C9FA" modified="2022-08-03" version="1">MRRVSSRANKNFSMRSEEDLEELMQTLITQIQLKLKNELHLREIFIPNSKADAKCNIFVSPNYASCPKLCVFMQPGQGMQPGIWSRQIHPKTGFQGSMIPYLKTAIQGGYGVVVLNPSTNHCMVNGEKINVQHSATPDDHVAYVWKNYIMPNAAHEITFVVYDSAGTLLKGLLSKLSSKDERRIAGIAFIESAHYVSSSDSPRVRQLLKDKAVNFEASSEPMFNLISSSKARLGCASLSVGRMGGSDNREWTVHSVQTSAFVFLQSVTNSIEEALAAIRATFPNKLVVTVNRARLTGQPYNNPYAVIQCVNQKKETVGNHKHTMDPEWNQTFSFPVTSSEEVVTITIKDRMFPLHSTLGHVSVQMGEVGLNRADRRWFSLRDEKSASSHGNGEVELTLEWVHDTFVARSDSFVRDHRGNGSQLQPATPQSRGTGNMSGDNACYSCRTAFVLHRRRYCRMCLRSVCTSCSDRLFLPGFSEAKRVCTGCCDLQMMLHNKVPRMLAAANTPTSRNRATDPKLAEHAQRMEAMRQREMAKEAEKKPMGIEDFDLMKVVGRGAFGKVLLVRKKEGKHAGNIYAMKILVKAHIIKNDQVENTKAEQHILKEISHPFIVRLRYAFQNADKLYLVMDYYPGGSMFYHLRKSKRFSEERTRLYMAQLLTALMHLHSKQIAYRDLKLENILMDPQGNIALTDFGLSKEGQAIEGAIRASQADSGMKTICGTAEYMAPELLRHQPYGKVVDWWSYGILLYEMLTGRTPFVDRNRRQMFKNIMQAEVIYPPYISPVARSIISKLLNRDPARRLGGGANGGRDIMAHPFFEPIDWDKLMKKEIEPPFKPEVSSVDDITNVPEMFQNMAAVDSPVNKKNGDGHHFEDFSYQEETFMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP94</accession>
    <name>A0A8K1CP94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP94"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12413">
        <property type="entry name" value="RRM1_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="229"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="317"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="494"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="677"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="413"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="823"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="420"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="825"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="860"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="929"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="969" mass="110412" checksum="3F01758EE93D8B9D" modified="2022-08-03" version="1">MSATVFVRNLPFDVTQDALEQVFGEIGPVKKVDVIKDKGKKKSETTTRGFAFVRFAMAADAQYAIEKLHQSDFRGRKMILEIAKEKVDKRKKAAPAPVVKEEVAPVEEEQVAEPEQVEEAPVKKEKKEKKEKKAKKEKKEEVEEEVAPQEEKTEKKKKDKKAKKEKKEVKVEEPEAMEEAEPMEQEETPVEANATGHVQSERNARRRMHREFLRQVEARKETSASTEEKSLLVYGLGADVTQKALFKKIKKIASVSKVELKEEEKTNKKYAIVQLEFLKDVDTAILKLDRHIFKGATLKVMRLQAAQQDAKNAGEGLRLIVRNLSFQTTDADLEKLFGQCGELAEARVVRLALEDPDNAPEGAVGKSRGFGFVQFRDGQDARSAIEKWNGYKLKGREMIVDFALSKAKYLQQQKEQENANGDEAEDMETETPEGEEVEDDDEKEEVESDIEDVDLDAENEDEDDDEEDDDEEEEEEEENKPQVHKEDSDEQRARTIFLRNLSFQSTEEGLRDFFATYGPVEYARIVYDKGSGLSKGVAFVRFKQREVADLVIERSQSALARQEEQEKNKKKKKKQQEDPFALSALADGDALMLDGRMLLVSRSVNKDDADRLTEANSADRKKRDKRNMYLAYEGTISVNKLSEEELGLPKLDIEKRRRAIREKKEKLKNPLIFVSPVRLSVRNLATSVDDKQLKQIFRDAAATGIKEGKVIMKDVKSDFVPTVTPPEKAQVKVKMAKVVRDMENVKPGKEPRSRGYGFVEFTEHIHALAALRVLNNNPQFTKVAAGGAAAAAKVKQGKSLADEDKSRLIVEFALENHGKLKLREKKQQDASKKREEERALKEAQGDDDEGKKQKKSRGQRQREQKKQQKDQPKEEKKPQPKKAKAAEPQRPQQKKRQRPEGDDLEQLASMEGGVMQQNGEKKSRKQRKQAKEMQQERSFEALVRDYKKEIFGGKSSKTGSSEAQDRWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPW2</accession>
    <name>A0A8K1CPW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPW2"/>
    <dbReference type="OrthoDB" id="64243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="77908" checksum="2852B981FD4213B4" modified="2022-08-03" version="1">MATLAKVATAKVLIQPLGHKPPSISSINTTRTAKVGKCPTPWQLFHLTRRLLGLAAAIFFVHATVESAVYGLVTLYGAVQYNSNYGSYVATLIPDYVGTKTIKESRLFNQVLGADSSPRQDAFYLQSVERVTNTKCEDIDNGVIEWLYSNKFLRSNWHDLVTRTSYNLTYLQDSELVAPVVDCSFTAITMGDITSARVFYLMRKKADPMTVFLVVTSISTQDYEVPDEFLQGAAAVVALAVIDDMRVDKVTNSFALALGYPLEGPWYSVYTFESVTDDGFVVLRNVPEDPNTEYRRRVYTANRSGFYLKSEESQSNINNMHWTIYDNPLLTMTKWQWAGCSVLKNSWGWVRCVYFVFAVYTIFNLLVLMIVVYRNFQRGKIWIGDAFISISGSLFLRGATVLVVWAMENFWQVSAAAVRYGSVIGNIVRVFTFPQIMHGDLISLYVCLAGFLGTVLHERIDPALTIFLFELGYRYRFEIGAWLPALKSLVIAHAVEDYLSGIATIPPELNSFCPFGFWTIHEMLKDASAAIGYITPNMMTFVIIIVYAVIRKAYRRAYPSRAVAYSSRITKGSSNLSEGKGMKSPFTMFELATGAELQNKVGIVSDYDNCVYIKGIRYASADGIYCNGFVIANGQWLIHTSDILSVVLIILTGSRLRGVFVYEVKDHKASQTARLVYPNTMKLSDLTKLNTTVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ23</accession>
    <name>A0A8K1CQ23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ23"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="15730" checksum="9406E9163BB9A24E" modified="2022-08-03" version="1">MAVMATKAELEQLWTLACLLSNQQLPHQALPCLEECVAAGETSQPPTAFVIRAHVLLAETCLTLCRLESKEQSRESRALVEALQRAETSIYVVEKALESKTHPPKVEQEWVMRLDQSKVLLVQQTSKIECVLVTGSGSVEGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQG7</accession>
    <name>A0A8K1CQG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQG7"/>
    <dbReference type="OrthoDB" id="10257284at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="46389" checksum="69DEC12FEBC34BFA" modified="2022-08-03" version="1">MRDDERGSGVKTMVSRPGEAARDGGDGGGRRFELVHVLAMFRHGDRSPITSKVGENVIMTQEEKQFWVSRLPEYDQLRYLNDGTQVVLRHESATGQVLGVKTDPPSPSHGGRWPCGQLTIKGVHEMTANGRRFREQYAEFLRNANPTHDVYVHSTNIRRTIRSAQSVLSGMFPEHFPDAQGMSSTQQPIAIHIDDRNSLGPSHSYELFQSIDGMLGDELKYGAPAGLEKTAEHVRRVAGIQKGRLIPWSGLREILMCRREHQLAFPTGIDQNLFSQIYEHDAWLWHKLYGSRDFCVGSFRHGVQRFLDQLDAVGKNNSRHKLTLFSAHDNSLVALMRALQVELINVLPHYGDMLIFEIHRDVATRDLFLRARFQGQDLTFHGHSHAALCPLSHVQALALEFLRHQPQQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRB1</accession>
    <name>A0A8K1CRB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP97 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRB1"/>
    <dbReference type="OrthoDB" id="5411518at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029488">
        <property type="entry name" value="Hmw/CFAP97"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290:SF6">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13879">
        <property type="entry name" value="Hmw_CFAP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="652" mass="74496" checksum="1E6413AC4D3E00C1" modified="2022-08-03" version="1">MTETTEAMELTATSNPYLDFYNEYCKTSRADLINVFDPAISEKKRKKMYKALDVSVAMKYAWAIPDERALRIIKHFGPIVEMGAGTGYWGRLLQLRGVDIICYDLHVADDDDEEGEPEPEAEEEVADGVEGEDEDEYEDEQEEEEEEHDGENDGEEDSAEEQEEEDDDDGEGEEDDEEEEVEVEQVYWMDVKKGTPKVLREHSDRTLFLCYPDDFEDSSESMALQSLQNYSGEYVIHVGELFGQTVCLPGPWGRTSSSEFQIHLASVYHKVLQVPLPSWHSSIDTLTVWKRTKTSIMDNAFYAFIPAEERLDLVEACPSTRHLLTEASNESNKKEKRVTPASGKDDEANNQSNKRYCSSSFLVQSDGFASCDVVMRSPGKPPLAYAAEYKFGDENVLTATHFEEVRLRNEQRIRNAQSVLKLKELTVQDDSASPSVHNPKRIQQEHDRQDLIEQHNLILLQRLERIHQHRVPKQFDVSHHTEAVLNAPRASNAGTRRREQEKIAMENKKMKRRLNKTKGTFDLKQLAVDADRHRYFSDQISKLTRRRKVQETCKQLSDVAAVKATHSVSPESFYVYKHGVKGASQTKYTQAFDDDDEENEEDDRESEPSKRIGPPSYLLPPVTKQRSKSTTCTPPMLKRTKMVSASDLLGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRM7</accession>
    <name>A0A8K1CRM7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRM7"/>
    <dbReference type="OrthoDB" id="342190at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032211">
        <property type="term" value="P:negative regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029146">
        <property type="entry name" value="Ten1_animal_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33905">
        <property type="entry name" value="CST COMPLEX SUBUNIT TEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33905:SF1">
        <property type="entry name" value="CST COMPLEX SUBUNIT TEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15490">
        <property type="entry name" value="Ten1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="117" mass="13191" checksum="F215FCDE7C6153C1" modified="2022-08-03" version="1">MITHGEIVQIAEVLRSPQLQNRSVRVTGRLESFDAARNLAVISFQGARMTVETNTMAMDGREMTVGSMYQFLGETHRIGGGPDDVRLRARVLRNVDNMDIDLFLQALELRRQFLAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRY5</accession>
    <name>A0A8K1CRY5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRY5"/>
    <dbReference type="OrthoDB" id="60251at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="29380" checksum="490CD1E29597A8B3" modified="2022-08-03" version="1">MWMPDNAFEECAGHFWGIHGTRDYMRAKFAYLETMMALGTPTSLTEALKEGLDCLRLCRADNLGVREHVSAIYVRLGRLQEGYDFIKWWATCDPDGRYDWGDMSLPYLTIKNADMTESVSCFERAYSLPHFGALTFIKFYAAQSLSDLIGAETASEKLPGGLESAVSTFLPFSEAASKSKSTQKLREKVSAQAKKAFGMAHKHNKHYWKAMLHPDEFMNQPPPQYISQGSMVEARSAFEHIFPAWHATPGGLDFIRQNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS19</accession>
    <name>A0A8K1CS19_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS19"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF92">
        <property type="entry name" value="LD17053P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="258"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="556" mass="62656" checksum="132767A757AF4BA5" modified="2022-08-03" version="1">MTEVVHPLPTAMRLVLYTLVGEEPEAVEEGKNRTPDANFNAFPLRSARESVRLDEVLRAFPLGDAYHFAFRNEQGVYVDLTNPSAVVPTWQRKIVARVTPLECAPEVKYIKHQVAEEPVPTYTEHVDERPDYEEYQSFRGSFLSVDDDRTSHDEREAERPDRRWKSPQSRPMEDQYDSAGSRNSNAGNMNADWLRKQTEQAKDFAKKINMEDAKKGASETAKKAKKWGASLLSSVSASIASATSAVKNDTIQVGGITVNVVRPLADGAYAQVLLVRSNGSGETMALKRIICQSEEVERDVQTELRVLRTVKHLNVVPLIEFGEARLQHQEFYFLFPFFERGSLWDAIESARESSSPLWPFSQRVALHLFRGICAGLLAVHRAGFCHRDLKPHNVLLTSSSAGEDFMAYIPVVTDFGSCAPIRVEVRSRKNSLDLHDEASRKSSAPYRAPELFEPVIDGVIDGQSDVWSLGCILYAMAFGSSPFEHPRDGFMKLACMNGRVSFPPEQNGVVRHRSTQFTHEFCDFIRDMLHTNPEERPSVLDALEFAEELLSDEMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC9</accession>
    <name>A0A8K1CSC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cilia- and flagella-associated protein 97</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP97 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC9"/>
    <dbReference type="OrthoDB" id="2163395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038792">
        <property type="entry name" value="CFAP97D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029488">
        <property type="entry name" value="Hmw/CFAP97"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33768">
        <property type="entry name" value="MIP11318P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33768:SF3">
        <property type="entry name" value="MIP11318P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13879">
        <property type="entry name" value="Hmw_CFAP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="21409" checksum="2C3BA1CC105CEA5A" modified="2022-08-03" version="1">MDRGRKAIPTLNKHTDSKYYQKCQEIHRLKLNTIKSSIDNSEPHRPLHLRKNLKKEQMKEERYAEIERENRILLEKMSHIMQNETLDNKNQSITYSHSLNKESRKRELQKITAENQAILRRIQMREPTYDHLQWAEEAKRNDQYAANIREYPEREREGSPSGDLRTMSAYSTGASDNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSL5</accession>
    <name>A0A8K1CSL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007573</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSL5"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="30366" checksum="9999237576BAF0AC" modified="2022-08-03" version="1">MSSSSKVWLITGCSSGLGRELAIAARKHGDLVIATARKVEALEDLKKLGCETLALDISASEDDVKQVVDKAHALYGRIDILVNNAGYIIFGAVEEANDKDISEMFDTNVFGHLRVTRAVLPYMREKRSGTVVFIGSGAGYIAFPINGPYGAAKSAIAGISQSLAQEVAHLGVEVTTVDLGMFSTNILSHEREFSQSLEDYAAMKKALQERMAESSGSDPAKGAQVLVEALTKTGRCVGRALPRRMPLGAGMLGFMHAELTARGKELNEWEDFTDPETLAFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSQ9</accession>
    <name>A0A8K1CSQ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA excision repair protein ERCC-8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSQ9"/>
    <dbReference type="OrthoDB" id="361494at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000109">
        <property type="term" value="C:nucleotide-excision repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="127"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="328"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="468"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="56594" checksum="234D71AF3F1B3765" modified="2022-08-03" version="1">MERRRSTAFTYVAERSLGLRNDFQDAVYQEEASHMQAVQRNYIYDGGMRVWCMELDPVDDRFLLVGTSKSFINLYDLQELDTKDATLASDSTENYDTNHRLAPCCSVKAQMIHKDLSLPRSSTSSSAHGLSFGISAVDWYPIDGGIFVSSSFDGLVKIWDANTFQVEAEFAFSSKVYCAKFSPISSTHSLIAAVTANREVRLCDMAADASIHSLLGHQDEIWSLAWSTSNEFQLCTGSRNGEIRMWDIRRSGSTACLLCLNHEGQADVPGRSSLHTNVKKLPSTSLVTASRPSQVAASKRRRLDQKVKKARSSSERSDPHLAASVSLARAHSAAVNALSYTPDGRFLLSSGHDHRLRLWNAKTGEHQFVNYAGIQSTHISRNTQFAVLQEGEAREGTIVFHPNGSQGEITSYKVHSDAGQPLTRYTAHYRHVTACAYRKSHRELYTGATDGLIMRWKPTPVDLRLKSQEGSDAEDKHAACTEQEVDAWSDDDDDEGNSTQDVFVPPILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT93</accession>
    <name>A0A8K1CT93_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT93"/>
    <dbReference type="OrthoDB" id="166511at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="21272" checksum="B8AF4C0388613A9F" modified="2022-08-03" version="1">MEKSKMSDREERREGGGDARVPAPPPPPPPPPPADLIDETMLPPSMPVPTPNDAMPPSNEPSKPKRLEIRDILALFHAPVDGPAEQRGEWESMWQQALVDAREELRVQQLERKKLKKRGGDGDSSVTNTPTRAPGGLSARHASAISSSGLGSTAANDKRPRQTTAVDSDPNKRFNRLPNRPKNSKLMQKLGSRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTG1</accession>
    <name>A0A8K1CTG1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTG1"/>
    <dbReference type="OrthoDB" id="271080at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033558">
        <property type="entry name" value="IFT25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33906">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33906:SF1">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="11"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="100" mass="11077" checksum="25FAE93A9A7A997C" modified="2022-08-03" version="1">MDLTLDEEGAQVTAASSYDSNYPPKNILDGEQSTKWMTTGSFPQEVIVQLATTATISRVKTWSTNAKEVLVEICSGPTPNKWERLFEMSMPQPCEDTVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU29</accession>
    <name>A0A8K1CU29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vta1/callose synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU29"/>
    <dbReference type="OrthoDB" id="391137at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="4">
        <location>
            <begin position="30"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="374" mass="39941" checksum="F7F4460BC29C490F" modified="2022-08-03" version="1">MLVTLPFATPASSKSKKMSDAKIPPTFKTLLPFIRRAEELERDTSRPESKLIAYFCRQYAMELGIKLRENDNSNEATNYLLSLMDRLEDDKGKLPTFSQDEGKEICEDFALEIFTKADDEDRAGCADKNTARTFYAAGTFFDILNQFGDVPEDIEEKRRYCKYKAATILKAIKEGVAPTPGPPSEGFGGSGASAEDMTVPQSQPTQSPPSNPLGNLTSLTLNSPVAPSAPTDFPSLTGSVGAFGPAGGLSSPASTNSSSTASFQTPTPAPAPSPPTAPTYSPPPPAPTYSPPPPAPTYSLPPPAPTYSPPPVAPTVQTSYVPQVVPERRARGGPVSQNEINDAIECAKFAIAALKIKDVDLAVQRLEMALKSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU46</accession>
    <name>A0A8K1CU46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_006188</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU46"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03001">
        <property type="entry name" value="PDI_a_P5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472909" description="protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="24"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="6"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="142"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW68720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="48436" checksum="0DC1B5DDF8EF9FF9" modified="2022-08-03" version="1">MGVKTWLWLMATLAVCLQSAVDGMYTSAGPVKLLDPKSFRDLKKDSGVWLVEFYAPWCGHCKNLAPEWKKAAKALEGVVNVAAVDCDKHKDLAAQYGVQGFPTIKIFGEDKNKPTDYQGQRTAKGIVDAAISETRKIVKARLSGGAKKPEKKKTSAPSPSSSNNAKSDVITLTDDNFDNLVFNSGDVWLVEFYAPWCGHCKALAPEWEQAASDLKGSVRVAAIDATANEQKAQEFGIRGFPTIKVFGPGASSPSDAKDYQGQRTASAITTFGLEALEKLGGGLKIKELTSQEVLTDFCSGKSSCVIGVLPHITDGGKAAREGYLNTLEEAAKKVRGKPFKFGWIQGGDQPAFENQFELTFGYPSLVAVNVDRKRYIVQRGSFSADSIANFLQGVLVGREASSGFSEFPALKTVQPWDGKDVKVEVIEEEDDDDILSEILGAGGDKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUC0</accession>
    <name>A0A8K1CUC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Micro-fibrillar-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUC0"/>
    <dbReference type="OrthoDB" id="1111734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="216"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="470" mass="54039" checksum="D8BD60B5D29C6717" modified="2022-08-03" version="1">MALFTKKDLGLVLPDDRPGDPVSLRHTQSKDDGTEQFKELKPKVDPTTKVRRYRAGQVPEFAAGYEEERGFVTPGQQVRGASKLKAASTSTSATRKRIEATVITSKDGSKEDSGSRGRRSEKPLSEDESSSDAAPTRNALDDSSSEEDDDEIDRRRQAMRRKMMEKQQGEQTTEPARRVVEAKVVRAVVPAAQPSMARKEETESSGESGSEWETDSDESNEGEALMKPVFVPKKARETIKRQEELDAEEEKRRQKEEEKAQAKKLETRKLVAEELQREKEGEQTGDMTDTEMPDDTDGLDPEQEYRDWELREMRRIKRDRDEREERRKEAEETLRRRNMTEEERKAEDEKLKKNAPKEKSKWKFMQKYYHKGAFYMDDTSVREKEDVRKRDASGATLEDNFNKEMMPSVMQVKNFGKSGRTKYTHLAAEDTSKKDSLWGRNDAIREKFRSRLSGTRDLDTAGASKKRKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV39</accession>
    <name>A0A8K1CV39_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV39"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039918">
        <property type="entry name" value="PPP4R4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="277"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="674"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="745"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="795"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="685"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="850"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="898"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="938"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="965" mass="105456" checksum="0A3C62325F356AC1" modified="2022-08-03" version="1">MEELSFFNEREAECFEREDTLSQTDLEKLNVAEDMPEMERAEHLLKNGLEKQKLSVLSTLSKILASNNSKANLSLLLDCIKHIWQKCEAETSANSILPLEILKALAALTCATVEGKVLSNPAVSLHEEYSQQLEICQEEKKSAIFLLTEEQVAKQLVPLVLDFIGDTHQKDYAEIASLAVIACLHRLAGSVKKTQIIRVAMEKGDVSQPPGSRLICCMVLGAVTALSLLSPQDIEGLYFQKMMAMCQDTDAEVRKCMCIQLDALARAVGEVKACEELLPELLELLQDEEEQVKQAAFLTLLSLLDFFPQSERIKRIIPQLQSIVETLPDYLLPLLAEQYGSMVNKLAELNSLGNDTAPSFFQGYSKLSTREDAELRQLCAYNFPAIVKAFGNNFISMLMDDILVKLSSDCVEKVRQHIAAGLHEVALLLGPQRGIRYLKSVLVTLLKDESCIVHGTILSRMPALMSSAFAIINDEDQKGVILDAMLRSMVLYHSVLPASRNREQLVFVETLQQFPLWCSSDQIYEMVMPILFDLIEDGARPVQSLAIQTLVKCIRRNENSSHRFSLLSKLRGEYGHARSFWRRLLYLDACVYALDINSRQYCRLNFIDIAIELLEDAVPNVRLKAITLLPHWKIILTALSDDKMLDRIRIFLEECSVDSDRDVADAISEARQAIENNELSHHRRPQEEAEDKRRVSEEENLGLVSDHEDSSADSKWSSMLEYTLVVGKDGQVVRRARVKSLDLMNRLPGRPQGKDMSRGTGMGNSGLGGSSVGSGGLGSGVNSGMSSLAMAAKIDPSKSKLAPKTPTKPSSSAGTTLPNCGTSRPLNPSAMATKMPPTIKVMGSTGKLNTSGSKSAMGSSRSTAALSKESSTMTKIPIIRPSAPAKRESSPSTATKPSGSPSTALLSSSGPSTMMSGNPGPPAGSGLATAAMKNKLGSIESSGPSSSAPTAMRPRTMAPSSASKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVE8</accession>
    <name>A0A8K1CVE8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVE8"/>
    <dbReference type="OrthoDB" id="1055097at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF213">
        <property type="entry name" value="INSULIN LIKE GROWTH FACTOR BINDING PROTEIN ACID LABILE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="630"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="917" mass="103252" checksum="CA051504D2AB5DBE" modified="2022-08-03" version="1">MVACLSLTAANTLQLRNQRISNVTMVAWGDGAPESLVFVSVSNKTVLELAQSDFASIMEVDLSDNRLVTVPTELFRVFPNVQRVVLSRNPIQELPPKLFSGLSELQEIIMEDTVLTGFPPTFIEECPKLRRVQITGALVHTIHSKAVRDLPLLESFNLSHNNVTTLFSDSFQGLPNLHTLDLSHNNLTVMPDGVFLLSKSWHALDFERNNITTAPNGLKNAVVDGYVSFARNLWVEVNASEFANASQIRELRLNTMGIFTVNSKAFSGMTSLKRLDLSDNVISMLANDAFDGLDNLEELLLHANQLREATFTRFPPQLKTLRLDSNRLDELPQSTLTNTAKHLQNLNLSQNWLWRVDSLSAFPNLTTLDLSWNRLEQLTSRTFDPVNASIRSVRLEYNEIASVSRSMLTSMIGRRLINITIDPNPGIGFSSQVEFRSVCPRGSVYEVVKVANTTVYGCVQCAAGSYHDNSSNTCALCHDVSKRAYTAVEGATTCSHCPMSANLHSSRDDCHSVHCSWYCWLTISIGLALPVAIMSGKYAFRRKETLFTPMQEHKDEDVDWLMGQLQMQIGRLSPGSDDTPSKLYDLPREAQLSVLSAIRDQFFQRRAEGPHHLIASPRPTKWSDLEWSSFQMSRILSRNYHSEVFLGEYDGRQVVVKRLITLRFDMNELTGAISDVELLQSLEHPNIVAYYGTMWNEVEHFCVITEYVSQGDLCTLLEMEVLGDHNVYFRIVRDVIAGLAYIHARGVHHHDLRSRNVLITSEYHAKVNDLRRNIDTKYQWRSLVVDKEQVPFIAPEVLTASSDDAKSDIYSVGVLMVEMWCGRFSEFRNISPSTPTNAKEALVDESDEDDVVRFMGKVRAYFQRNLTTTADDTLVGLMEDCLHRDPAQRPTAQTLLNQLDALLVNPSAEISRGAHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW28</accession>
    <name>A0A8K1CW28_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW28"/>
    <dbReference type="OrthoDB" id="546383at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="21853" checksum="D767E2B5F182B25E" modified="2022-08-03" version="1">MVSRGSSVHHMRRSSNPFMTTSSGVVGINLQEPVAFSAPRLSNDNQQQSVQSVSSIKDFMYQTTSQGLGDGFRAQDRSKLSQCMDKLTLRKDVTEKGQVKINAIDVVSPYEYALSPGDVLPPPIDTRSISDARIEHPMYATSNRDIGVEKSQVKVELDRRSRPNTFTNSFNGFRYRDFGLNTAITKSRISDQLDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWB2</accession>
    <name>A0A8K1CWB2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWB2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476502" evidence="2">
        <location>
            <begin position="20"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="566" mass="61442" checksum="4A51AF8A86DB6C8B" modified="2022-08-03" version="1">MIKPRSALLVLCAFYFAMGNPTPVPLQAAPQSPRQPQSQPRNFGDQFPQPTNDRCFRLPKFKTKQARGQATCTPGYHQTNGLCWPECPVQYPVKCGPGCLVQGKTCRGDNLELAVQVAWGVANVASAGLLKLLKEAMTVHYKVMCGYHILRALGEGFKMAKSFTGTPDALKKTLLESPFAQEHLPAAIGTCIGVYTPVTFLETNIQAAQRLYGTVEAELTTKTTPIVGAIVDLISKARGTEIKTPDQLLAFLKTNKINIRLDNLTADEKLKISNALTEQANGNVWCAGAMRNLIQELTTYASKQMATNPQFSKDQVHFDMATVPLYYDQIPRVAGICYPEANQAKNREELISALGFIAEGIADQAVKAKSTKFLRRAFLGSMFSAGLDLIPYFFPPAQLVTLLGRWKSVCRPTVLLGEATDGPITNLGLKILDSTFAGTTGAWKNAGDGMAILSFVNTSPKYTAKIHVRSGGYEIPGLTDFELPKKPATGNAVPTPKTVPLTALQGRALYFEVGPCWRDFGSPSGTMLLWVPVLTGRGSLKMDIRVTPNPSLATTCKSAMRGTTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB98</accession>
    <name>A0A8K1FB98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB98"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="49205" checksum="D77DCEAD4AD2E953" modified="2022-08-03" version="1">MTMGRMVVAKRFVHGEAAAKWQTWRCMQQRMPGFQMSQMLPERRVSLGAVPLRTSNTLYLRGKHTEIPFTGFELIFLGTSAGSPSVRRNPTGLCLRLDKSNWMFDCAEGSLRQLMKSTIRVPSTDKFFITHLHGDHLYGLPGILCTLDNHNAAFVETRTKKPAPRPISVYGPLGLFSYLNTAFATSSTRLSNLTVTVHELVSPEMLDKASNFEKYMSKAPVHPRLRREVIHAESDGNGLIWKVFEDENHRVLASTLKHTVTSFGYVVEERELPGKLKPELLIKRGLRPGPQYRLLKQGKGVTLEDGTIIQAHEVTGPPVRGRKVVILGDTADSSRMFDIGRNCDVLVHEATLGHEMLQQAVFRGHSTARMAGYTARRMNATLLALTHFSHRFRHWAPNQSFGTTQHLTLEAQLTFGRRAVMPASDFLRIPIPRHPHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBF8</accession>
    <name>A0A8K1FBF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acetyl-CoA acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBF8"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="27"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="291"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="43916" checksum="91AE3FD9DC51924A" modified="2022-08-03" version="1">MLRPSVLKSVKTLQRQFSTTVGPRDAVIVSYARTPIATFNGSFASLSGPELGAIANKAAVERAGISPSQIQEAYLGNVVSAGIGQAPARQSVLKAGFPNFIPCTTVNKVCASGMKSIAMGAQSIMAGSQDVLLVGGFESMSNVPYYLPKARSGYRLGDGKVVDGVVHDGLWDPYNNQHMGMCGEACADSFGFSREDQDAYAIESYNRALEANKRGFFEKEITPVEIKQRRGDPIVYTKDEEPFQTKPEKIPSLRPAFKKDGTVTAANASPLNDGAAALVIMSGAKAQELGLKPLAKIRGFADAAQDPVEFTIAPSKAVPLALHHAGLQLQDVDYHEINEAFSVVSLANMRLMNLDHNRVNVNGGAVAIGHPIGMSGARIVGSLIHILQERDATIGCASICNGGGGAGAMVIERLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC56</accession>
    <name>A0A8K1FC56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC56"/>
    <dbReference type="OrthoDB" id="76256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="115" mass="13208" checksum="95352C5CFA3DC71B" modified="2022-08-03" version="1">MINMGTPAPRRIKLYCQDEDLRRRHEENARQLLATAQSPSCETDTSAILAKKALRYRKVLDRMDGVDVTSPQFDASKFLGVHWCKRDEDNACVNEDEAETEQSTEVDMDQDFKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCJ7</accession>
    <name>A0A8K1FCJ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCJ7"/>
    <dbReference type="OrthoDB" id="165148at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="431" mass="47600" checksum="74FAFF5804A625B9" modified="2022-08-03" version="1">MATTTTSSTISIEARVEQAQLQALDSIWQQCMDDLGMTDKSDTMRLASTAETEALLVPTAEETASLMDFLADSCAEASDKLEDFSYEDVAKQLAQAVAATQQSLRNVKSNVQQVLDDPMKMQALCDKFETANQHMRMIEHEIQQEMAAQDPEVKLLLEQEEETKMSTALTKREEELPLALASNEETLRTVMQFTESVCTSLDDALSTITKDEYDLAAQLSLTLAQKLLQTGQSIFSSLGDQHRQEAGLPTGDRSERITIEELSDDDTPIPTASAKRTKLARYQKKQTAVLRTYVEGLIEKTTQSASDRPYVAAALGTAALPFIGLMVPMASVVGLALVLEKFFPERAFMIAELCSNAAQMMKLWFLLLKITSRQLGMVAKKCLISWHDHASHYGYVATGMEIASTGWSLGCLGASWFWQSAMRYINLGPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCY1</accession>
    <name>A0A8K1FCY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCY1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477578" description="Protein kinase domain-containing protein" evidence="5">
        <location>
            <begin position="41"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="478"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="369"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="764" mass="83465" checksum="D15E244CDA3F5BD5" modified="2022-08-03" version="1">MRPRFNAGGLALSIGRLCVRFGVALVLLQTLSMHVQVTCAATSTKKPTYTMYNCSDIVTVSGVCTNSSDPNNAYRFVCIGVEPDSCPSKPTVAKLDSNTLDISNQGVEQIVGMEDLSNLLKNLYMQDNRISNLTLSYGDQRGGNLQVLQAANNRLESFASIVVPMALTKVNVSGNPMPEIYVPEVYSNLQELIALETTLTALNLKDAGGLLTVDASYNSLSSVNDMNFTNQLRYITVAHNKLTDWRDFKPPIALRHLDASWNNANHFIRGDWSTYDKLETLDFSYNLITEITGTIFPAYPLQIDLRGNPLQLIEIRSSDLQTFQTSAIFIDEVAPLAADCKSDKATKESIGNFSVCVYDDDDFEALMAGSSDGSSNAPSSSSSSSSGSRNQPGDGVSGSSNIGLYVGVAVGVVVLIAIIAFIFFRRRRSAMHADDTPYSDVTKLTITGGSTGSSTNSHIIEALQDPRFVSLRVDPDDVTVLQELGQGKYTTISVVRVGEHEMMMKRIQRKLVLEDPNIAMQFIAEIQLHSTLEHPKVVQFLGVSGTSMVDLTMYCELMPNGSLATLLLGLKDSRNSLGWVRSVDSDNEENEHWLPSKLDLAIDVVEALVYLHSYDPPVVHGDLCPRNVLLTADWTAKLTSFREHQDVGAVVAGRLGSISSLAPELLTGHGERSPASDVYAFGMLLAELDTCEPPFRSLTNARTNAQLAAEITERGARPALRPNCPVEIQAIVWSCLEANPSQRPTCVKLHYDLSQLRRAMQMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD08</accession>
    <name>A0A8K1FD08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purple acid phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006394</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD08"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035489561" description="Purple acid phosphatase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="7">
        <location>
            <begin position="46"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="160"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="6">
        <location>
            <begin position="371"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="51358" checksum="38B5510498351877" modified="2022-08-03" version="1">MKWTLAGLFAVALSASVLFNSHADVPALSGSTSLRREAGLLEQALPTQVHVSLYDKTWSPAEKNVGIAVSWATGTPTQRSMVRFGRSATELPKMVEATSPCEQYEFCDYTSPWFHHVVIPGDLLEPNTTYYYRCGDPTGGWSELLTFTTSVAVGSQAPVTFAVIGDLGQTEYSEQTLRHLINQDGLTAILHAGDLSYADNYQPRWDRWGKLVEPLASTCPWMVSVGNHEEERPCQDGADRFVAYQKRFRMPYDVDDGKQAKNQYYGFRVGMVHFIVVHPYTATDANSPQYQWLSEELGRVDRTLTPWVVVIMHGPWYNSNTAHQGREPHLRMKDDMEDLLFEHKVDLVFSGHVHAYERSFPVYKEVVRADGIVYVVLGDGGNREGLAPTYIHPKPAWSAFRQANYGFGLFHVLNHTHASIEMYEDREAGSARLHDQAWLTSTQFRATQALTAVTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDT2</accession>
    <name>A0A8K1FDT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hsp70-Hsp90 organising protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Stress-inducible protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003164</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a co-chaperone and mediates the association of the chaperones HSP70 and HSP90 probably facilitating substrate transfer from HSP70 to HSP90. Stimulates HSP70 ATPase activity and, in contrast, inhibits HSP90 ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Homodimer. Forms a complex composed of HOP and chaperones HSP70 and HSP90; the interaction is stronger in the absence of ATP. Interacts (via TPR 1, 2, 3, 7, 8 and 9 repeats) with HSP70 (via C-terminus); the interaction is direct and is stronger in the absence of ATP. Interacts (via TPR 4, 5 and 6 repeats) with HSP90 (via C-terminus); the interaction is direct.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDT2"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23159">
        <property type="entry name" value="Prefoldin_URI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="326"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="396"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="100"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00056105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="451" mass="50391" checksum="4850DF8CDFADEE24" modified="2022-08-03" version="1">MAQAATAIDLANPRLLQEKLERTREQILALQEDVDKYSDVAATIAELPKKLKHDVMVPIGTRAMMPGKIVRSNEILAHLGDEYFAWKTAVEAVDVIDRKKKALAKQIKAEEESLDALQEKKKDVNNLLDIQKLYEDENIKEIHETEEESESHLVSRATEEDIENYFEIEEEERVKNEGAEWDWDEMMKRVEELEAMEDRGDDVDEETKEPEPPALSKEEQVAQLKAKGNDAFGKRRFKESIDWYTKAIDLDSSSHILYGNRAAAYHRLKQYTKALADAKKAVELDGSWVKGHYRMASALSALERYEEAAEAFEQAFELCPTDEKLKQQANEMRAKTRPSASAPSAPAPAKVLPPKDQPTPSPTPVVPPPPAAASDSVASKVFSGSILERDVVQEKPVVSAPASTGAFPTRRPSRFMGNNPDGKVVTFEPVGQPEPVKRVSRFKAQRSGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE29</accession>
    <name>A0A8K1FE29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE29"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14385" checksum="F415205DA0E3FBDD" modified="2022-08-03" version="1">MSTQQQRVWRTDRHDKSVDGVRISSIKLTRAPSQQPTTTMNNFTIANATSLHFSQACSIVKKAKAEDERNTTSETSQARFLRKVQTQTQETAHTTDTTTSQQEKTKSIWRRQLLISNSLFRSGGKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGD7</accession>
    <name>A0A8K1FGD7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGD7"/>
    <dbReference type="OrthoDB" id="156249at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="393" mass="44629" checksum="58E77A1093F31B03" modified="2022-08-03" version="1">MDVVDTRDRVDTSLLDILIDMPSSSEAFLASTDALMVQNEIEDGAQSMERSSCGDQSKEPMRNPSRDRFRAEMASLREQIVQLEEQKGLLEHKHEIQTHVVSATSVLWKSIAQMQSEWRLQTERENEHLKQALDTQFRIVKQLEDALLTKPPATDLPSTRQAKDSEGIRHVYLRYIDEVQRAYEHVDVALHWSDGKSSGGQWVERTVADESGSALKCVEIRDQKWLPFELSRVFNALWRAMVNDFAHSDPHGETSFAEPECFVNRRLQRDGLLVSETVMKKFVQQDRMAIVWRSVNNLRESLGGIGDRVFSTETGWVVVERVRGVDAESSTRARTCARHFPQWDSDAESILACKTDTFVKLAMGSTQDDIAIITEAVENILLEDVLSTPHGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHD1</accession>
    <name>A0A8K1FHD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHD1"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005683">
        <property type="term" value="C:U7 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071209">
        <property type="term" value="F:U7 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039267">
        <property type="entry name" value="Lsm11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21415">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21415:SF1">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="190"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36215" checksum="9B0F185A1CC00B7D" modified="2022-08-03" version="1">MVVAPDEMEARLRAFYAMVNPGNEQNIAEIVRKYRGKEAALCARLQKKYGKAPDLVSESTPTMDTKANPVKAVSAYDPHYEVFKAVECEESPLDFRSSAFDALKALTTASVKPLVSSVYPLDNIHKCRHLLPESDPNHQRLVTVTPKPVAPKPSTKTQAAASTDTPPPADGFFSALADTYLDGPFTVLRRCFLERKRVQVVIRRVNSIRGTCSGFLKAFDKHMNLVLLDVTEVVIPFDVQLRREAARRDPTSQSTEPLFSVADPARNHRFITQNYAKQLFVRGDNVVMVMEERRPAPTSKERKAEKLHEKSQRKAWSKGIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ86</accession>
    <name>A0A8K1FJ86_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ86"/>
    <dbReference type="OrthoDB" id="70257at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="456"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="61748" checksum="8267336B53C4E038" modified="2022-08-03" version="1">MGNTVTLHSACAYSDLAAVRRLLKTCTEAEIEARDDNGRTPLLVAVAAMKRRNTADDDDDELNGFGFHDDEDEDDEFEGTNEPRDEHSGNDGDDEGDDDESLGDGEVVELEDDASIEPIAKEAEILHLLLQRQVNLDHQDENGWTALHHACFIQNAVAIRMLVQAGAHPMRDSYGLLPQDFLMRGQSSEWIAQAQELKELMDQITEVSPYFIKLLAFRPSGIVQLDMGAQVEKGSFVTIEYNVPENHSPKDYIQVLISAEDSPDVEIGTYHQVPAGSQGQITISTQDIPSSSTIRFVYVKTDINTISRKVVASGCNAVVQASVGEIFQYELFLYERVVEVESIPEFEFIDQPLIILKRIGIVAHEGEIDWVEIRPDNHIVAVNDIRIDTMEFPEAVRVLQENNGKKCTKLLMQNYSACGDFIPEKILGVGVVGKFAFLQAIHDDDHHVSEQRLDDWVGDETRNPPPAPTRVDTAHLHSTATTAEPETPSPSTEAPVEAVPALHEAVESKLVLVEADENPAAASAEDKVSLSSTIETVVPLHNSRQLVEQLHHGISSAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKV6</accession>
    <name>A0A8K1FKV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membralin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKV6"/>
    <dbReference type="OrthoDB" id="6779347at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904294">
        <property type="term" value="P:positive regulation of ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF4">
        <property type="entry name" value="MEMBRALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47249" checksum="03B14EF34C1990C9" modified="2022-08-03" version="1">MDGAVDGTNRAPMATTLERSYFRLYVHMMRYVQQISSQKMLHYFEVGVFVVALHLVGLLAVLHLSFVSAEGTNACLSSLIPPHIRPDGVHLMRLQIVPDAACVLHGIEPLTGACSQGRSFSPPIASYMFASERGYLSFFTKPPPATSSPLLRLENILTVQISRSDAACFGLRWEDVFGPLVTEVIEYVVGYDTIMMNHMRKWRAVETGAILNEATSVVYEMDHGFATRPRPNATWIERIAFKVHVLYLCVSLFFVCIALLSFVMKETQLRCLRLTDVVVNRLPVSNDDVTTLVISYFMQSLVLVPVVLGMLFFLLEVYRDHVLAFGVLIILSYGEAFSILCARTRLTQMYYPALFFCWFTVFHLYLVAFPYGFTHTALLCFGLVLIETSLFFTNCFEIPALSRREISSTVIRERVSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL25</accession>
    <name>A0A8K1FL25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL25"/>
    <dbReference type="OrthoDB" id="65504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="648" mass="72770" checksum="31D7C6E714D8E18B" modified="2022-08-03" version="1">METSTQTCYISYTDRYANPEAFLDFPTGVYYEWQGVVDSPELKPDGGRYNTQIAVRLFTRKFGAVINYRIVSSSSTDTVTAADLIGSVIKTGSTSLRYTVAKSGDVIILPSYSCYIYAVAVKDGMLTSPLVVSKEYKIYASKYLFLVPSFNGDYHGRVVRIQLDIRGKKRPRPARFLEFSDYETTLGMGPYSNQVYVVDMATVNPDLMGFASAFSAFGKVAFLNETYLVPAKDDPTYFVPTWRFVLEAQYTPHPKRVAPIPPPRIYQDAEYLYLAPLFNGKTYPSVILRVLSMTFNTTKPIIQQLDLSTVRPDLRGFTSCFTDDVKYAYFVPQQNQAGLAGKFMRLDLDDFSPTGVTVFDLSALNPSFVGFTGGFKYENYAYLVPFQRPLQGDEKTTTLREFPVTNSGLVVRVDLTTFATAESLDLATIHPQLTGFSGAVRVTHYAYFVPFMRDKSPSSIEVNVYSGLLARVDMRDFKSVEYLNLTSVHPHLRGFVRGFAYKQYVILVPHRWAFYDPAEYVHSGKVARIDTTNFSLDGVTFLDLAAASRSQVPDMPDKDLRGFYGGAVSGKYGFFVPYFNGGRFSGKVCRINLDKFDEVQTLDLTQLDANLRGFVGGVLSKVQEPLDTDLFGEFQIRPGTTTPYEYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL65</accession>
    <name>A0A8K1FL65_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL65"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="141" mass="14416" checksum="748AECD146147FAB" modified="2022-08-03" version="1">MGRSRNSRPAPARRAPAPAAPKRPAPAPATRQAAPAPAPAQSSGGGMMSGLMGTVAQGMAFGTGSAMAHRAVGAVANSFGGSDAPAEAVEAQAPVAHQGEDACINNQKAFLDCLNVNRNDISSCQFYLDQFNQCKQQSAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLD6</accession>
    <name>A0A8K1FLD6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLD6"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="254" mass="28805" checksum="F0C9815D59CE2770" modified="2022-08-03" version="1">MPSPRDSERTEGVDDDVLQQRFQRCATQTAGTELDLSNLQLTGFPVEILTLFPSLRRLNLRQNALESIPDEFPRHLTHLVSLNLSYNALTRLPDHIGKLRALQKLSLSHNQLSALPSSFIGLHALEELDLSFNSLQTLDGDLGSQLLKLKTLNLAHNQLLEIPRAFVELMMLRVVDLSGNDRLLNVPDKIRRLHERNVILHSRAKRRELISRALRVRYAVQQIVEKPSPMVVSPTKAASRKKTQQAQRISVIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLI4</accession>
    <name>A0A8K1FLI4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLI4"/>
    <dbReference type="OrthoDB" id="167910at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026">
        <property type="entry name" value="PIGMENTOSA GTPASE REGULATOR-LIKE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035473712" evidence="3">
        <location>
            <begin position="25"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="885"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="631"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="783"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="920" mass="100887" checksum="70B4E9AE334DAFFB" modified="2022-08-03" version="1">MQLTHALSVAAAVATALSMSVVEATPVAQYRASGVLETFDALPERVSWDLPTTALRHKHHDDDWDDWDDADWEDERERAEKYKKEAEKYKEEALKRADKYKKEAEKYKERADKYRKEQEKRADKFQKEQEERAEKYREEAEKRAEKYKKQAEKYKEEQEARVKELEDEVHTLNTHGHGHGKDEDEDRDDWDGEKKKHKEEEKGKRHKEEEKEDKHKRHGKEEEEKEKHKKDKEGEKEKHKKDKEDEKEDKHKRHDKYGHGHGLDDEDEDDYDEPKRGHMGWGDHHKGCDDCHDKPHWRPHLRSHGHRHEHDYPSHPYYHGEEDPDYKSPDEVEPGNDTIAFAQILQQDTESFIADLRDWAIGIVGGTNTSELIVDSEFTLTTTGEVDVRRPCGDLVSHQVFSVLKEFIEDPKDAELTKKLAKQILWHPSRECVRNHQTIEVDGGAHAEILVACGDTPLMNATSASGGISRKIFGHNIEASGAIVVVDFLNGTVTTFGASGPLGTHLNLRNIPDDVDEILGNLTDTVRECAANSTLVIRGVVGGGWRQEHASWGSWDDEVETSVVGYAEAFELSYGSSKPDLPSPTETPLPPYIPTPLPYEPTPPTLPPISSSDGSSADVTEPPTEPPSSEAPPSEVPATEAPSSEPPATEAPATESPLSESPTTEAPATEAPSSEPPATEAPATEAPVSESPASEAPSSEPPATEDPSSVPPATDTPATAAPTTTPPTTDIPTSEPPANEPVSTEPPSPESPMTTPPPATEAPVSPVPPYDAPVTEAPTSEQPVAEPTPAVTVPNSDAPAPAASTEATQGPVQVPADLASAKLEDLSSATSAMYVHSASACQDHTAVESCFMNAALGKVIHGDFSSVPLTMSEIYEHDVMGSSSAPLPLIGMLSLVGLAAIAAYKTYSRRHGYQPINTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM0</accession>
    <name>A0A8K1FLM0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005868</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM0"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="164"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="385"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="735" mass="81946" checksum="9CCBE3586FE3DFE1" modified="2022-08-03" version="1">MDGADHIRRKAVVCAPLLAETAAWDVEEGAVVSSGQVLGSVGALELGTHQQLVAPWHGSLRIVAKEELKKELNGDVNGKEDGESDKNQEKSGEEPAVVVAYVEYCIHPIRNGRTCLMCLAIVDENDLEMEEEHRSVSVVSHGQKLRLNVEEAKKFDLANLQRQLTNKRLSLVLDLDHTLLHAVRVQDVVGEIRESPDTHFFYIPGTPQHEHVVKLRPGLTSFLEELSLTYDLFIYTHGTRLYAEEIAKIIDPEGRFFRHRIVARTDTPDMQHKSLKLLFPSCDDSMILVLDDRVDVWKENVGNVFLIEPYRFFKGAAEINNAAGQGSVGVEDEDADADIDKHLFHAKRVLTHVHQAFYENGTKEISLEDQIAGKGSDVKQLLVEHKKSILTGCHIVFSGLFPIQGPRKPDSHYLWRLAVELGAVPSVTMDNFPITHLVIHPGRLDTQKHNQARSMPNVQVVTPEWMLKCARVWERVPETEFLADLLKLKQSKKAEARTMAEEKASEEAQTEDSAKSLPEADDKESKANETSEPNGSGVANGEHSEAKETVQSNKPLPPPILTKEPRNGETPKKSVKFSPEVADNSPTSGTIRRRLVGRRPLNRPVTGVATRIPENKGTVASGGTFDFLSKITQHKREQQKPAETKTPAQQAPKKEAASAPKDIDDAFLRLIEAEEEETAQEQKRKRESDDVKDMLAKRRVKREKPSESAAVTLSDDEDDGEDDLDDLEADILDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN08</accession>
    <name>A0A8K1FN08_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN08"/>
    <dbReference type="OrthoDB" id="120556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="754" mass="86664" checksum="2C94E63BD7AD3A95" modified="2022-08-03" version="1">MSAASWTDVQDESERSTRTPSEQVPALSSSSIVKGRRPPRFEFVKVSPWAYRFAWLGILTLHLFCMGYLALVAKLYATLPGTYLDTCLDFYALGMKRQHYPTIAFVHWFFMAGHVVLVALMLVFSLIERRLVFSPFQHTNIQPLAQKSADRGGRRVRRTPAQILMDNVIRQLQPLVARVYDPFFGRLGLFGVESRYFDMVMILRECTETVLQSYQAYRMSLHVPRVWLNRFFITMLVINCWVTPVIHSISRSKRMTHRLLWLLSDAVLDLLSSIGVPIILLLRYAKDYDTSFQGFDTYYWYDDTWLINFMNEFQLVLVVSWTDLLTRAMFYAGLIGCMESVKDLVRPKRVRSQKTYAGTEADAAKSKQSFMTPMTARLDTAHLPWVARVVLPKLELLVRRLKSIIHGTFAVWGIAVLVLHLYAETQKNMEQCLMQVRPWTASKPACALLIMDCHIDNVPGLAEDIIPQWEIADEATVTRIVIRHCPQLHMPTRIKAFPQLYAIKIYNSTIAEWEDDAALTNTHHSGFSTLLMVRTNFTDGQLPPGIMSKDFPQLLYDIEFQITNLKDLPDDLDTSWLVGSYLYFENCQFDHIPPVLHRIAPNQLSMAFNRFTSFPFDVFQIDGLSYLSLAGNPIDTLSKTPYEDVVDVGTVTRFYLLETNISFIPRWLDPLITRMTDRPSILIRGSPFCQHVDEIAAGSRTQFPEVDTMPSNELSKVMSSTKAKLDALENQVSCSFPDVLFYPYSYEDKWYGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPX6</accession>
    <name>A0A8K1FPX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein transport protein SEC31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein transport protein sec31</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_006287</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">COPII-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPX6"/>
    <dbReference type="OrthoDB" id="542917at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000526">
        <property type="entry name" value="Protein transport protein SEC31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="7 15" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="182"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="269"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="17">
        <location>
            <begin position="577"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="901"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="933"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="978"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW68819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1195" mass="127794" checksum="D6A95CA5DDCA7AE9" modified="2022-08-03" version="1">MSLLKEVQANAAVAWSPVRRRGELLALGAKGDGGVAFENTGGEFKLMSMDFSDPSTNMVTLGAVKTPARFTSLAWRDIAKHHDTCPYGVVAGGMADGSVTLWNPKAMIEGGSEGASCEIGRITRHKGMVNAVQFNPHEDSSHLLASGGSDGEVYIVSLDKLNSPAVFTPSGGSITQPGQPPNEITCVAWNTQVNYILATGSQNGSVVIWDLKQKKPWCELRDPQRGTISAIAWNPNEGLQIATASGDDHRPVVKFWDLRTSTSTPLAEFHDHSAGVLSLSWCPNDPGLILSCAKDNRTLLWDLYTRRTVYEFPSDNSSAPALGSDQFFGGGAGQRRWNVQWSPKIPAVASACTLDGKVQVWGLSGGGNPEVRPPKWTRRPAGASFGFGGKLITIHNPSETAPANGDRRRLIHIHRVASEGPLVAEAEALNQALELKDFKGHCDKKVASATTEHERSVWSFMKVLFEEDARQHLLLHLGLDAQKISQLNAKFNPHQEEAAPQQPEDLLNQRIDSGLAAEDVFSSEYQQNEADASDKSSPLGNLPSLAKALPAIDDKSPRIDVSPSPLYTQQSESTLMEALLVGNFEVAVNCCLHYNQFADALLLASCGGPELWEKTQRAFFAHQTRPVMRVVSAIIKNELYGLVEQSALSDWRQTLAILSTYAKSEEFPALCDKLASQLEAAGDLQSATLCYMCAVNVEKTVAAWVKESEAEAKIRGYTFALQRLVEKVSIFSQAVSDSDQAMGPDVASRFAEYSSLMAAQGRLDIAAKYARFSDVSCAILRDRIYNAAPVQGYQPPPFPFDVVNVIPITQQQQQAQAYGQQSYAAAGQYGATAAGQYGAQATGYGAQAAQGGYGAAQATTVGYGAAQPAAGNYGATQATPAGYGATAGYGAAQATPAYQAQAPTPAYNRPTPAQPSYQAPQATPYGAPAQQSGYGAQPQQPAYPGQTQQTGYGGQQPGNFPAPQQPGTFNRPAQPSYPGQTPGFSSGPPSTGGGAAYGFNAGGNVPVPQGTGVNPLTAQTSLTSSRIAKPSVDMNSQKKDGFVSSVGNKELTLKYGNATTAVLSPMGGAGGEPANKFENVIPGSTENVTPQDMPIVHAFNDLVAQLQSLPLTMMEQKQMAEIQKSKEIMFTKLNISDLSPSVVARLHEMVNCFAQRDFATAQAIHVALTGSDWTQHKDWLRGLKSLIHISMKRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQP2</accession>
    <name>A0A8K1FQP2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQP2"/>
    <dbReference type="OrthoDB" id="72704at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021640">
        <property type="entry name" value="Mediator_Med28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11594">
        <property type="entry name" value="Med28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="145" mass="16426" checksum="37F2F8AA55E9A26A" modified="2022-08-03" version="1">MAEETQANGSTAASVRNGETSLKEMNTAFAKCLSLVCPPIQYPPHCRFNPVQQDSADMAEIEARLEEFFLHAKEIELLFLNDAATDGEREEGEGNESPAELELEILHLENELSEKNDLIEKYGDVIRGWEGKFRRLDNRMAPERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2G5</accession>
    <name>A0A8K1C2G5_PYTOL</name>
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        <recommendedName>
            <fullName evidence="2">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000155">
        <property type="protein sequence ID" value="TMW54942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2G5"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="581"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="2">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="651" mass="71708" checksum="B728E6FD6E2C05B7" modified="2022-08-03" version="1">MDQKQLQLRREQPALFQDLTDPKAVDLAAATIVSEGVGYIGPSIFMASLAEAIAFSFGCISPMPAVLWFAAFSCVAVAINWVLQMTLLLAIMTFDKRRELKGKYDIVCCVTGGPSHSEPVIMVDPKTPDDGVGMVDSHQYSASHFFDRCIDFYCRILSAPLVKLFVLLAFLAWTCVSIVSIEDLKHGLPQAESMPSDSYMTDYFNTLDEYLATGPPFFFVVEGGYGRNPKAFDLYDQNVLAKFCKSKDFCEDFAIPKIMEALANSMNGSVTHIAKGVTYSWVDDFWGFSNPDNECCRIDSKKAYIPIQADNITYTNARKQESTCMATTVPPVPKESFMSLFSMFSTASAGSLCSYGGGSIYRGQFSIDQKPIPVVKDDSPQVVMNSTGYGKQVSAFSYMVVSTANPKQQDYIDSYAQGRRAAQWISDKTGIDVWVYSISFVFFDQYLTVVKDTYTLVGLAIVAIFVIHVIYFWSLFFPLVVALAAINIVVQVMGLMHPNDIMLNGLSMVNLIIAAGISVEFCGHYVRMFAKSSGSGDQRAKIALRKVLTSVLFGITITKVVGLSALTLADSRIFQKYYFRMYMTVVLCGVLNGMVLLPVVLSLSVDVKNALFGGNRDNDLMPEVLESSPAYHGAETGKLRHSHSTGNSVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3A5</accession>
    <name>A0A8K1C3A5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="615"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="712"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="750"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="783"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="6">
        <location>
            <begin position="952"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="71"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="836"/>
            <end position="872"/>
        </location>
    </feature>
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        <location>
            <begin position="1081"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1190"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1277"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1424"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="71"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="841"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="862"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1287"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1438"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1470"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1513"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1537"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1555"/>
            <end position="1574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1574" mass="174804" checksum="A88FB26C69507969" modified="2022-08-03" version="1">MPSPRNAAESALNMELSHSRDEFRTEERGNARPSVHFGNVYGRDEYVAVESPRNVDTTAARVVELVTRLSGSPSTTQFSHPPSSTEEGADESSTAASTSLLPRSSGSNQRSDRVLLRATSRFRSLRRLYSTASHHTDGSALSTTSHEHEADTALEIDDHESSSARKQPHIQMGNDVTTACPSSHYYIDPQGRLQARKTWWLYTRLRRLAAHLVPGFKRDSNSYLCAPMITNTGFILSTYLLRLVLNQAVLASLLTDQQEDKCHDFSSEFLDTFSFTLAGNVLLCLPAFHFNMCKLFQRVPTAKQQLRNKLRAHANGSSTVVDPPVLDNPVVGTGATAAAADGAIVHDDNHPKLRKTYLFSICEVLVIFEIPYLIYTFVTIVFPTASIFHSGRDTDVVTVSVRCGRDLPFGLFLLFLIAQLVGLIAYGLRWKQIILFHRMHEHFLYQRGCVPGRARFDYIEQSFRTSWFASARSKQIHQIKAKLYHAAKYGEIDELKRQLDAAIELDGTDFAQHWYEPRPPRLLSLVPFLSSTRFMQCQRNPLHVAVAFDHAECVQELLSQGLFDIHQGEKMEVLKLNISWLYRFFFDIVPILRKSNYARHESRLIFGPVGLFTSTLLTPLHVATSMGNTDMVLLLLRYGANPNYVAQSSHRKFATPVLFWAINKECARLILDADANPLYVPGNGYCLTAFEVARLIGNHVVAREMEKYGGDVALTPLHDASARGFKEEVEFYLEHGADPNTLGEKVTGFFRRTPLHWAAIRGKTKTLKLLLKYGATIDARDAFGRTALTWACLLNRTKAVEVLLKFGADVNVRDNIGDPLLCICAAGTCSSPSTGAFTSDGEGRAAGDNGEHTGSGHGHSHGPGSSADSSSSRALDPEIFALLQDYGIDLHTTREFNGDTALHVALRKCNEATSMLFVRAGMSLTAVNYLGQRAMDCTMSPSLRYLIKKEAGHRDVMISYCHSHSALARKVRDALENAQVTTWIDSMDPSGITGGSVWRKEIAHGIRSSALVLALLTRDYPVSQWCMKELAFAKMHNVPIVAIQCEDMEISEELQVYLWTRQVVDFRRAFVERILESRNEDLEEDEARKPTHAGTASEDQDEELLLLQQQDPRDLAEAQGEGDSDATALALPQVVVKHEYDEDVFRNCMRLLLDGIQDQIEEYRVRRLVRERKHEQMGHKHAELVDDIDEDEEDGEANKGGLCGVPGRTFRRTHSMTPSEALRGPNSPSGSVAGRSPYVFIAHGDYHLNFCTRLKSALQKQGIRCVVDHSVPAIQYNAESRGGGSGASKTPSASYGANQHHSNESLSSPSRLRRINSTMSTGENATTSVQARQLAAKDAILDCAAVIIVLSPLSASCDMLADQLAFAEDRGKLIVPLLLSLQNIDLAKRYTFSRSIVQHFNISIGFEQSLDRLALYLHQSTEATARQQQQHQLEEHKQHRRRRRRRQGHSSQNDIGALGEEEYSDDDGRSSAASSPASSVRSGVSRVSLVIGGPHSPSSLPPPLPIIHPSRQPPGSTSGHGWSIGTPTISPSDHHPHQTHSPRQHHHFTLEPLLRSQSLVSSPSHSRENATWSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3H1</accession>
    <name>A0A8K1C3H1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial 2-oxoglutarate/malate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3H1"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000156">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate malate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="106"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="204"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32506" checksum="C801802D3C0572A0" modified="2022-08-03" version="1">MSSFAQTAQPYVCGGTAAVFAAVAIHPIDLVKVHLQLAGQTGAANVTSLGVARSVIAKEGIPGLYSGLSAAVARQMVYGTARLGMHRAVSDYLIQQRVANGQSASLPLAVKSISAMTTGAIAATLGCPMDVALVRMQADTLAPAAERRGYTNVFDAIFKITRSEGVMTLWRGSVPLVARGAAMNLGMMASYDQAKEVFSARYGEGFLTNTGASAVSGFACAFTSLPFDLVKSRLMNMKKDPVTGKYPYTGVTDCFRQIVVKEGPSKLWRGYWTYYTRCAPNAMIVLLVVEHINSIYRSAFGLDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3R1</accession>
    <name>A0A8K1C3R1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Beta-Casp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3R1"/>
    <dbReference type="OrthoDB" id="5600060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027074">
        <property type="entry name" value="Integrator_9su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-Casp" evidence="8">
        <location>
            <begin position="248"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="527"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="880"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="704"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="527"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="829"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="842"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="896"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="914"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="994" mass="112066" checksum="8378ED02CD3CFD06" modified="2022-08-03" version="1">MKLIQLGGANDALCHFLSFGGYELLLDCGARVLSQDPTLCVELPALHAIDVASLDMILVSNHANLLALPYLTEYLGFKGVVYATEMTMEFGRVLLEETRALLEKEAVRVSFRGAPSSASLPLFTAADVTRACEGVKCVEYRELVRLAYGVRLTALSSGYSLGSSLWLLESPSDRVAYVAAASGDLNRHPKELDFAPLIECDALILTDIKPDRDPQATTERTVEQLLAGVNRVLDRGGVCVIPSSPCGILFDLMEAIYAACLYPRSSQQQPTVLPMYCLSPMAEHVMDLTQCGAEWLCEKKIEKLYAGEPAFLHESLLQSNVLAVADTLSTSVLSGLQHGGVVFVGPSTLSFGIGADLVRTLGHDARHAVLLIDPSVDPHAQLAPFFSLEIEKLVCPIDARLSCGDVNQFISRCSPRSLLVPHEFLMETNTSSVKSETEPSPFSRVFPLHELIVSKSKTELTTFPMKQLEAVAIDKPSKYIDGKLDLDLAARATVTDVNGKAAATISGVIHLREDEYVVEAAQRHMLSSTLSNSAPQQQQSTSDEARHAGSKRKAPSAATISPISSALKSHVVEYRERTNILLGNVDEEKLLKQIKAHDPHLDVYISQGPDNADAMLSIPALDARITLWKEAAKTVIETPKEETRSLLLPMCEAMEMRFAGSSGGGTQRNDLNVLPGKFQAGLSNKFTRRHVTNFEDTTLMAASAAKLRAEKKMERQALAIEKQQEKIEREMKKIEEITQRLHRQQMREANRIRNRLQYAAMCIQTAYRHHRLSRQQREEELKKKLLTRRIQERRRLELVMKARHDEEHEAMERKLMEREEKLVRLHLKTTHRRHHEQRLKRQTLEQQREERERMEMMREERLMRLHRKFLLRPTMTLETVPYAKNISDQSEEEEEERQRERHHHLDQPRRKGSRTLQNEVQPCQIQHNPRIKEANKTIKHKKPRGGNNSGNQERGNNVNSIFSIPYVVEDAAEFDYGDEFEDVVDESMLSRLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3S1</accession>
    <name>A0A8K1C3S1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3S1"/>
    <dbReference type="OrthoDB" id="161065at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="550" mass="61343" checksum="163F54DBF723381F" modified="2022-08-03" version="1">MKDTSRMLKGIGDAIAVIPGAFGFAGIGFSIAASVYTIIRGMGNRDDPILVALSKLHEDFSQDFDAIEAAVKDVNTKTNVIISGIDQVLSDISKIPAKVVAEMKLTDVTQMKDKFANVQRAALQYTQGNLTSDQMMAKCDDYDVPSLFSELETILRDEKNLFGAKFGALDMSNGQVQTQLLLFYFSVIPIATNCNALKYSLASIQSDGEKIDQVIKLVYDRLSWYLTPPDRTIHVRERFNPFASAFDTDGLKDTPEWSLSLSFRAYSFAPPHAACFEAVDEGHRLARLDLPPTTKLPKPTMFCVKSEQTDDAPIRVAYAERGKEDDTGRHSIIQPEEGDHFFPLDSRGWNQNVQVLYVAKTANWDTLPYVTVISDFLVVEGESKTVSIDDVTAQCRAIGEGYDRDGDGHSKDYPGAPWTIFCVKYVKTSLREIDNQSGTFLADVEYNEMDAGDAWTAKCPKEGYVRDKSQITIPSKIKKQWLAGYSTIRSYAICLKWENMTTRSTPNQFMGRVWLDDSQTMADKPRKSRLEGGRVMALRPSPSAEQADQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C510</accession>
    <name>A0A8K1C510_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006433</name>
        <name evidence="3" type="ORF">Poli38472_006441</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C510"/>
    <dbReference type="OrthoDB" id="128354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="967" mass="109216" checksum="EBA157B4E996CCAB" modified="2022-08-03" version="1">MSHASSDRETTERAEEHYMEEEKEDMADDEVHESKAEAVDATAVVLEWLHRNGMAVKPTGVKVLLSLDDDGLAMVSEIQRALPDLRMPPKAWGPLIKFVQDGVKQHEKEDPVSLDSNALELRNEEFTQPYVNQEIPYRLEACINKCWEQYCAKRPTLSKDAVFPYTTIVQSSGFGKSRLVRELAVLTNKRMPNARMRVLYVCVRQSGSSSGYPTKTHIWPDGLFPTAYPQNDQSLQETLSVLLQTVFHNAMLDWANIGNRCFSHFENATTGKATYEAYTRKLFPSNQQKYAGNRDKPCSSYGSRRVLVLALDEARWLLETSANDRTGWFRRFRRALNHANDAIAQTYGNFAGIFSVLIDTNSKISNFTPPSTRDPSSREPKTGKSMLFPPFVLTHTMDIMLERLLEMKYGERYVKGTLSSSDYCKFLLMPLEETREALASMGRPLWQQYKIRKTGRPGSQDSSDVEWVKLLWLAAEKLVGGVELDTIVKDQSNSLRAVTALLCRLGIRPHSWSPLAPSLVADYMAVLSHMNCTHDQFVGSYSSEPVLTFGAARVWYKSVVMPRSSASQLLEYRLLPELRKMLHQEALDTGEVGEIVARMVLLLAMDATGVVATGNEDERCYDGKFYSVATFLRTLSGDSEDVRIERGEMRDVETLLEPWESWKVGFSHFVKVSQEPTKEALWAMLARRSACILPRNFKGINLLIPIFTPSDNSNEPAVSMIVIQVKNRKGRDAAFPDSATISTRPELTFKGELSKFAIHEVLRIYMSLHGVKRMEQFFTVDPGIRKGPRSIEKEIKAGKIVKTEGPPKPDAVVLCIRGLGGWFAKSLTKGATCMEGDTEVETMELENLKTVISSGVATQLTSFLGPYWKLEEMVLADLDQRDNLGESYGMDRDEVIQIANRPMVKTVLARTWKYHATDAEALFYNDEYDDDDDDDDDDDMDHSYKTKTKQQLGSSSAEPVNKRFKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C676</accession>
    <name>A0A8K1C676_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C676"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="28154" checksum="DE41062B874C4AF6" modified="2022-08-03" version="1">MAYNGTVWDAVRSGDVVTLKKFFFVEGASRLLRLHSKEPEEGGRTLLHTAAWWGQEEAVQFLLTSGASVDEIDTTASRTTALIDAARAGQGGVCALLVRYGADASHKDIAGDTAFHWAARRGHGTALLQMALELDIHDRRMFDQVWTIRNGKGKTPMDMVRGNALLFPLLQRRLGARFLSEPKVEKQSRRSRVPFKTAAMLGASSRSLTLNPSQITIGNDGSRPTTSDGHTPMSLSGVDALGLGIDSFAYKARDSIPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6S1</accession>
    <name>A0A8K1C6S1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4200 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6S1"/>
    <dbReference type="OrthoDB" id="10264298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051147">
        <property type="entry name" value="CFAP_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025252">
        <property type="entry name" value="DUF4200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13863">
        <property type="entry name" value="DUF4200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4200" evidence="4">
        <location>
            <begin position="38"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="164"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="390" mass="43612" checksum="5F198561B074638F" modified="2022-08-03" version="1">MEPRLSALGSAGAAMIMGRPSKVPQTLTLDHVSPATRLLEKRRQMFEVQEALDAQKEEFARREDAFHRREEALRKKDLELQESLIKFNKFLQENESKRNRAIKRASDEIKQRLSKEQDVARLKEHLALLLVENDKLSQDVKKNMKYARYLELVQETVPEDYPEVADLVNRYRTLKETNRDLSQNQVQHEQENESKRLEFASFQKERANEILNYNNKIASMQRELESDEQRTLRLQHDADASLRMTTQKTLALGQIVMAIGNLLQRCTSGMHGQILKHMEGSNAANASTTTTANGTAPGGGSESPLKENKHESLSETEILQRGLKAMSDLDVVAAYMVDFTAIVQARVDAQRAQKKAAAIAMAAASGIGPATTTTQAVAAAPSQIDASSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C701</accession>
    <name>A0A8K1C701_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C701"/>
    <dbReference type="OrthoDB" id="129807at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="612" mass="68711" checksum="446E0AF601EE7FB7" modified="2022-08-03" version="1">MIPVMDHLAGMGKTTFCQHYLHKCRALPPTKDDYQKPFEKALRSSRTVQVFVNEGSFVNKPSLSGAMNEAVAYAIKKKLINADDLSILAAPYPASSSICMQDLVDRVGPLFIVLEDIHIGFSKDPVVAQTAFEDLCRQVLVPWTQVVGLFFVVAGKTSFFESFRGEFAEEPWLRTRGYSIDRVKLSLLRPDDISTILTNTLVGDSTKNTLATRWELKSSDDLELAVTRLFEWTLGHPRDLRVALQQHKTFPDFLDHGNEYSSNVADWSELYQKVWSWRSVLVQWIPYLDISDCDDTIVLSNVKVKDEKVSGVDVIAQCHLKWEGTLEKARIVAHRAVKDAIVSVTLGMKAYISWEDARISHLSPSDATTACEWMCLKRLQDLFSIETGWEVPSSSFCEAVRVIGQYIRGVGDDSEDTQSHLGFPEAVEYFPQITKSKKRWRPSVRAESAHPAVWPILLAEMVSILGESAHQSVCFKARPRSLSPSALLMTRRTNSEAARLVTVGLVVKAIATQSDLDMECKQFDVMFDRRIHESTHVGPMTNALIVCATSLGEALKAKEVYRVVEPPISCKYVNHVIVLDLSSPERRAAFFDIEYQPKCIESAEAIVSISQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C780</accession>
    <name>A0A8K1C780_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C780"/>
    <dbReference type="OrthoDB" id="74014at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="68" mass="7364" checksum="0A1295FA0194FF62" modified="2022-08-03" version="1">MPHSRELANKKNDHKDRQSRGRAGSDLTNAKKGGAGAHNWGVSTADEGAIQAIDRKDPNYDSSDESNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7B1</accession>
    <name>A0A8K1C7B1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7B1"/>
    <dbReference type="OrthoDB" id="166440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="405" mass="44291" checksum="52DAFDC085A48540" modified="2022-08-03" version="1">MAMDASPPALVPAKRLLFVSPWTYRLGWLAVVAAHVTKLLREFGYVEDPAMLVYQEVCMNVTALDVDHRFVAVMTTSILVAAGHGLAMVLAITRSIHSRQLCFEEPSTDPSKLSFYTFRIGFHLYASRIGDQATDAGCILSTRPWFSSTYTCTLVDLSCSENVISGHHSELKEVMKHMSIVELRQMIISDCPELEMPREIQVFPNLQVLIVHNSSLVRWDTDAAITNDAHPVLEYVYIIETNLSDVFLHDNLPSVLHDIGFSGTNLTSFPDETALHWSSIAQLELEASPGTTSLPPATSQLAFCNQVSLVGNPLTQLPATIGAVGTLGWVDIAATNVEHIPGAWLPQYSEADQWILSAGARLAADEAIIETDPSIRANASTTNVWNLGTLMISCLDTTPLRSLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C831</accession>
    <name>A0A8K1C831_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C831"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="317" mass="35334" checksum="4E39E3AD0F55B298" modified="2022-08-03" version="1">MAPTSPLLRRCVTPLVLHEKLTITHNAALYRARPTQQPSNSKGSTTTSQMTFPEFVVVKDIRLATMDSVDHRYSDDPMQELRVATRLLHTGGHPNVVRFYGAYLESDAVRFVMEDCQSGDLYDHLKRQPEHRLPQRDALNVLLHVTRGLRYLHKLGFAHRDVSIENVLIGPDGQFKLCDFGLSSSADVVCLDTVGKSHYMAPEVVAKQSPYDPVRADIWALGILLFTMLTGSPLVQVASPTASEFQAFRLVGCRGVLNLWKLDHLVGFATVDLLDRMLEPDPSKRLRSTAEILEHPALLAAAARELNVSRTVTSTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8I1</accession>
    <name>A0A8K1C8I1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009927</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8I1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418720" description="Protein kinase domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="576"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="855" mass="92153" checksum="38600938C281F2AB" modified="2022-08-03" version="1">MVRVVGWTLAMAALAGVMGQTTTTTTTTTESTVEASVESTTVASDSDSSCVSGGKVTLTAAGDDAAVLDSSCKKTPLTVETLAKTNRTLSAASLGIEQVTSVPDIDTLDLSWNSVSSMKDLSKNAPKLRKLVLMSNGLSSLDGISLPPTLEDLDLSTNPLGSISGLDKLPLRTLTITNSSVTDISKVSMPSSLETLNAAYNGLTKFPSTDSLKSLKTLTLTTNSLKSFKEITFPPAVTSIDLSWNFLSSFDGFELPSTVTKLYLGGNLFTSLSDMKISNDLTILYVHDMDIKSLDGVTFPDTVTALSLMNCSLSVIKETKLPSQLVYLDISENSITALPTQLPDSLRSITATNNKFTELTKIKFPSSITKLEFGGNQISKVAGIVFPLSLESAAFGDSVITEFEVSRSDYLMFQKTNSLNATIESTSCSNPAAEKGVYGKATLCVLPDDVFESLYGSRGEGNSKSSSSDGGSSSTWIIPVVISVIAVVGVVVGIFVYRKRKEKQAQEQKPLPTHFPQTLADPTVFGAMGDIKLNSTEMSSYHSMFGTGSGNGAVTSGGSNGPDQSLIKYRIPTNEITLQRALAKGGFGIVYLASYQSQDVVVKKILPEKSSDDRHLKAFLDEIKLCSTLNHAKIIKFIGVSWNTLSDIAVIMEYMSGGDLDTLLKKQHTRKAEYPGEFDWYASTMLPTKAQLALDVLEGVVYLHSFSSPIIHRDLKAKNVLLSDTYEAKLSDFGVSKEWRVDTTMTAGIGTMAWIAPEVLRGERYTEKADMYSFGVILTELATCSKPFDGVTNALIVLKVTSGEHRPDMGPDAPEDIRDLGLRCLSYNPMDRPSAMVAHYELKTLLKAHCSTFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8R7</accession>
    <name>A0A8K1C8R7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8R7"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36954" checksum="5E4A7DF722DD93C9" modified="2022-08-03" version="1">MDFSKCQRIQRRLPVKFDAEVMYTAAERGVLAEVAWLHRYTDYQAKEAIERTAAACHVDVLEWLLDHQDTANKRSDRQTSQRLRIKLRQFESSLRATCWSDLVEKTAYCVMDGVGFLPPNPSNVELYQLMDWAAKEGNLAMLQRLHEDPIGTKTCSFLAMYHAAEIGDLTMLRWLHKHRTERNDYMIAVLAAAVEHGHLAAMDWIRDAYFTGPMVQPVFATALRAGQVDVVRQLATHFEDQVRALLRYRYSMPNNPEMVEYICEKLGYELAASDLDLVWMLGKKKLGKDSMDELVEIAFKYGHLKCRKQLLDAILRTTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8T2</accession>
    <name>A0A8K1C8T2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3 5">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3 5"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8T2"/>
    <dbReference type="OrthoDB" id="1659429at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF13">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="293" mass="31990" checksum="06A3A844C65D8738" modified="2022-08-03" version="1">MSKTVEITHPSGARAEVYLYGATVTSFYTATEPTRNALFVSKKAALDGSKPIRGGIPLVFPVFGSAAGFPNHGFARVTDWTLTLLDQTTGDAESPAVATFTLGATDASKTMYPHDFELRYEVKVFPETIVTALHVANKSESEISFQALLHTYLTVDDVRGEGCVVEGLKGLEYHDKVTGTKQMETREVISFAKETDSVYANAPEQIVVRIRGVNGSDHVVTIDKAAFIDGAEKQPSDAVVWNPWIEKAKGMSDFDDDEYLNMVCVEPGRVSEFQKLAAGRVYTLQQSIHVSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C943</accession>
    <name>A0A8K1C943_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C943"/>
    <dbReference type="OrthoDB" id="10250083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="394" mass="44745" checksum="4D0D9AFF43899B5E" modified="2022-08-03" version="1">MVLAAGDITTFNIQHGYVEGLVRGFRSGFLDDVDYHHLTQCESLEDVKLNLQETDYDQFLADESGVVSPSLIQAGTTNKLVQEFQFLRAQAAEPLGEFLDFITYEYMIDNVVLLLKGTLNGRDVNELIPQLHPLGKFDDSIMRSICAFEPNSKGYSDLYETVLIDTPIGQYFSQFLEESASGDRMDGTSEVRNVLEEVQMELIKNSMLKLWLEDFYNFSQKVGGDTAVIMGEILKARADRMAINITLNSFGTPLNEPAMRISDRKPLYPSIGSLYPEATERLAEAGDESSLGACLDPYPVYRKIWEVHQSQGVDNKSIDDAFYERDVQMCELAFQSQMHFACFYAYVKLKEQEVRNIVWICECIVQKQRDAINNFIPIFSDSAPWRSTNQGKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9G0</accession>
    <name>A0A8K1C9G0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007281</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9G0"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IPO4/5-like TPR repeats" evidence="9">
        <location>
            <begin position="99"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Importin subunit beta-1/Transportin-1-like TPR repeats" evidence="8">
        <location>
            <begin position="468"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1151" mass="126781" checksum="AD14BA0728CB186B" modified="2022-08-03" version="1">MQSASDWEALLWSLMAMDNTERNRAEAVFAELKTQSDVTLTGLLDIVHSTRSDDVRGLAAVLLRRVLLRDAVSLWPEASEAVQTALKERLLTVLSAEENRSIRRKVCDTVGELASSILEDGQWDDLLPTLLQWMETPNVTLRETTLRVLEMIAIYLASMLESSDGDLQVQFERTVLQTLAKSLSDTEGRVAVNAVRALSMLLINMDSLEIQQPDLLHNTLALVLGALHRMLNTQRFDEVMETLEVLIEVTEPHAPYFKPLLREFVETMVQIADPTASQVPDGCRQLAMEFLVSIAENAAAACRKLPKNLFVNAVYPVTFRMMLELDDLETWSVTTCEDEEDTHEISNFDVGSEALERLVGAIGAKKSLPKCFALIQEYAARGDSWVHRHAALVGLCQILEILSQDELDEITKHLLTQANDPHPRVCCTAIDVIGQMSMDQGPHFQEAYHQQALTVLLHYLQDTEKPRLQAHAATALRQFIDMCAPEILTPYLENLLQQLFHVLQNAPLASSAHHVVREQTITALSSVATVAGQAFAQYYSAVMPLLHEILVSCLKESTTSGFSGAFTLGGITLECISLIGVAVGRGLFATDAVEIMKLMAEMQSTPAIVENEGIRTYLLQAWARFAKCLGSDFAPYLPIVMPTLLQAAMQQAEFEVDPTTMLRDDDETSSTTSSNDDIQIAQVNDKCLSIRTSILEEKATACQLLAGMVTDLEAAFFPYAEQVTQVLAPLMTDSVHSDIRTASISAMAALVRCVALANATNEQTIKQMVDFALGRLVHALTSEPELDLVMTIMQSMKHCIDHAQASHPHVVLNDAQLREVVQALLLVLADSFQRRAIKRAERSIAHGEEFEGEDGIVYEDVAVPTGDADSDDDESENVEQEVQFLMADCIGHLAKTHGAAFFPVFQGLVWEKIVELSAAHCLPEDRKLALYVLDDVLEHCGPPAMSQMETFVPLLVDVLQTSEGYPPLVQAAAYGLGVCGRLGGPLFAHHAPSTLQLLLDVVALPHAQESYMRNATDNAVSAIGLICEHHANVVDAATLFPKWLSMLPLRGDIEESVQVLQRLCRYVRERNEFVLGADGRHVALVVRVFAETMAHARSFTRGVGEDAFGELRQAIADALALLRASLPQDAMTQAWSTLTPTQQSALHALFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9K7</accession>
    <name>A0A8K1C9K7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9K7"/>
    <dbReference type="OrthoDB" id="36576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040153">
        <property type="entry name" value="Rcf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018:SF3">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="6">
        <location>
            <begin position="95"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="194" mass="21291" checksum="CDD6F31218A62E4A" modified="2022-08-03" version="1">MHSSLEHADAPVAKDIITMHAYTSGLKAGAMTSMVAAAGVYAANKNWAAFRTRLGASGKMGLVVSSFLGAFTIVSEKRLLAGARNPEMYLASLDPNYVEVKLHEHDKLKWYQRFANHVYDHPYKTLATVGVPLVGGIFAYQASNHSIQRSQQIMHTRIYGQGAVVVLLLASMGFHDYMHKRGRFVEAAEDAATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9X8</accession>
    <name>A0A8K1C9X8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9X8"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="301"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="11"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="418" mass="46280" checksum="66B802B706D95909" modified="2022-08-03" version="1">MWGILTNMVATRRSSARLQGKQEAAVASTESTPTKTEVSPGRSRRSTPNSGSKTKKSPVSSGKRSRTRKEDAESVSSATESDQASEEVTKQLFSVEEATTDEDPAQIPANVEKYEQPAAVETEEETEEEIVVETVVEETVVEKTVVVETVVEETVVEPEADPETEEEEIVMMNESEDESAEEIALGEEDDEQTASANEDELDEEVDVLAFAKMAASGISLSTSKTTTASTGASTSSIRLVPDALDSGASARTKFLEFDGSKLAQGAKLVEDTVAVEERKGLAMQLNRVAKANRQRDEATATKSAGRQWFGMASHEMSDDVRRDFALLRMRNYLDPKKFYKSSDHGKKLPKHFQLGTVIEGAHEFKSARLSKKERQQTFTDEIMADEDIRKYTKRVYGQIQQRTHRGGKKKRKMNTARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAE0</accession>
    <name>A0A8K1CAE0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAE0"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="739" mass="83906" checksum="55A94A56457A0FD0" modified="2022-08-03" version="1">MFSNVKKLKKIKVSPRRIFLLTLNVASTLLTLITGLRENPLIVFAMGRYDGIRARMRDGHLSYDIVPDDILDVSKMPDLVDAADAFRFISAPRRSPANLGEDRSTCMRVNAHRAPMMTLNFDDFWGKGARRIQVFAFSISARHCEVVNLLPAYVTSCIETHGNNATACHQFILEHFNELQTYHEIQTQAETDFGAPGKPFLKCKSRPPKPFDFEMDLMVQQSYWAGGSYHIEVQTSSCRAQPLLQDDHWTWELFQVESLDQAANVVIALPHSGLFARIVSYAYGFVTIVMIIQGVLAALIRSRRVQYLPQELRRTKEHRVARVIAPFMPIMALLAENENSVITFKGTVVMASDVWMNHWLYITLSILDAITSIRTTYVVLQTGTWMLKKKAAMENFIFLCGALTRITWLMCFLHTVIRLSLKLLLRSIKSMRIMRSSVRERIEWYIDGTALFLSYKIYNLLLCILLYLTLKIHGSTSLMKQQAVYKQGNYGGSLNIARFWGSEIACDLFIILSMLTLSGLIIGLALMRTKYRYLANSGVMRMLQDRYVFVGWDALTAAQMLKMDPYVPLHVDNDIALTGCSIGTLLQLFYASGPSGLVQLAGDYLFVDGGFSREVVKFRYPVKRAADMGLCATSRASAYRRDVDESSAVSPLRTAGKKLESNSNPETEQRAFSLFDRRLRLCTEGALGRILLIDVNHPGVIVKNPENGQREYEVRDALSFMTILDIKPLLQYKKRLRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAN9</accession>
    <name>A0A8K1CAN9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004674</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAN9"/>
    <dbReference type="OrthoDB" id="25498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="16"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="31474" checksum="1E6436DE67AB58BE" modified="2022-08-03" version="1">MPAKQLLLSTEAVCEVKVHPVVVFQILDRALRRSEEQDRVIGTLLGRVENGVAEITNSFAVPHLENGDEVAVGKDYHTQMYELHQRVNENEIIVGWYATTASGNALLDEPSCLIHDFYGSVCEMPVHLVVDTSLQNDGLQVSAFVSSPLELVENALVNQFKQIPVTQKISEPEAIALNAMTPAAVSEEDERAAKTLPNELVALEAAMARLYECLDAASMYVGDVVEGKTTADVKLGREIADSLASIPMIRADQFDQIFNSGLQDLLMVSYLSGLTQAQLSMAEKLINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB19</accession>
    <name>A0A8K1CB19_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sterol 3-beta-glucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB19"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000163">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="101"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="409"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="756"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="766"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1220" mass="134916" checksum="FE03CE8E5C5E45D0" modified="2022-08-03" version="1">MDASEWNGGNAQKTRREGKKLTEAIRFVRVGQRLTPREARPFIDLTDTAATFDKNGRIQLDFGREDTKYDLKAIQERTRTLLSFKIPASGSVDEQVPLMNICIMIVGTRGDVQPFVGIAKRLQQGGHRVRLATHAVYRDFVMEHGIEFYPLGGDPKELAAYMVKTGGHIIPLKLDTLIKDVPRNVQMIEEILNSTWPAVSAADLDANGKGIPGRPFQANAIISNPVTYGHIHVAERLGVPLHIMFPQPWVPTTAFPHPMANLTYDGKPHKRNYISYKLVDFLMWKGTDSMVNQFRGDVLGLPKIRKGGWGQDILLDLAIPHAFMWSPALVPKPHDWGHIYDVIGTVQLKGVGSTYNPTPELERFLGNDGGPIFVGFGSMILSDPAKTTKMIIEAATQANVRVLIQSSWSDMAGDIKVPSNVFFLGNCPHDWLMPRVSAVVHHGGAGTTAAGLLAGKPTFIVPFFGDQPFWGRAVVKAGVGVEPCPIGELTTEKLRAAFSHLMDPEVRKRAEAMRDVMAREDGVEEAVKSFYRHLPLKHMKCDVDGERLATKWSTKDKIKLCDECEFVISSRPENSLDDIILYHCVDYSARGPDTLLKGAASGTGALIHEVEKGWKDIILRPVKGFRRAGVKGAVVALVRSVFSAVFFRPIYGAALLADHLATGGYNQKRRENERKRGTMFGNKRLLVAVGQTTTPDAHVAGMRPDETSGEGLFKTVRDRVLVQLAQDERHRLVQRFFELNGNRSVVRRPFDSEPLEVAPTPVASPRGEHKEMKHSPEMSDKELSGLRDLADIENRLLMEKLERIGGKTIPKMNICLLATGTWDDDVQQFVAVALRLKADSHRVRVASHECYRDRITGVGLEYFPLAGSSGTVHSIVGHIEVRDPLEQEHDAAVRLFVEESKTPVIFAGFQVEGFSRDQVDKLVQDVAHAAGEANCRVILQLVDQSSQEPLHRSAVLFQIPSDASIHSVLPCVTAAIHWGRASVTSACLAAGVPACVIARNPFQRFWGHAVARVGAGIEPLDATQLSPQTLVQALQALQYPHVRDKTHQLSSNVVSSNDVIEKTVQSFYANLPLEAMTCDLDPTRIARIYDQANELKLSYEAQLVVQSLTDPDDRTDLKYKPLKYAPSKPPRYSLRRLSVTSLVSQPSGSNLPRLIYADRFDHLLSSASPMFKTALLGARLAIAERVVEAPAPWTSPDVAAQRRDAINAQYEALLASRSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ5</accession>
    <name>A0A8K1CBQ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBQ5"/>
    <dbReference type="OrthoDB" id="2148418at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="516" mass="57655" checksum="E4823262D70DC19D" modified="2022-08-03" version="1">MPDDDSGDVREPDPTDVNQAAQLAYMEQMYTTIQQLNAELDRERADAKRRAASIESHVENREHATLDVLHGIGAEVEESENFGVVGAQIPIGGAGVSSAATVNKRFRPHQPRPTALPDPKAALAKEQLELCAALGKNAELRIRNREIEKQSESSSQVLEQTQRQMKMAERRIANREEKLRGLLKEKLHWQNEMKDLRELVVEEKMRQVDLLRRLETTKREAIAQVDAMAQMLRDVEEENQALRVHLVETKNQLASQTKKLEDVVRQSRDEKEKLVECINEARSKFKEWKDGEANVLRAQKDQAVNNLKAEYELKIARHQEEKQKLRDKVKDLEVSVRLMQKDRSLSPLELSLRKAAILGGRDSAGTTEGEVIEANVRIKELEAMLEHTAEYQKRQENIIKVSQATISRLLQEREVAALDGLASQPLLGSNGLVNSSAAPPDSSYFPFGAVSPIPGPDNCETAACHAPEVLEAVPVIGSPQPLVGDPNTLSSEYAQYIPTQRGATGMETMTHQSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC35</accession>
    <name>A0A8K1CC35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC35"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="250"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="386" mass="43644" checksum="3C1EF38A7E244B0C" modified="2022-08-03" version="1">MRERLAEHVEVDIRQHVLVTPVHGKKRRIEALQYVIRNRETQVTTVQVDFSASSDVQLVFPPKNRPQLTQNAPMIFDFIVYPMEQRVMVAVVKDGGERAFVRVQYEVKDIASVPQETIATERGRRDAALAQLITRAARTYNGLNVDLSRKSEAAVTRLCADINGFNRSKPDIFVDSAFPPSPASLWGKVTIFHVEDDDSWMELKISDTTSIDSSFQIRFTATPGEYVIAVNILPSTLQQEASSDKWTEASIKSNLQLLFDCLDADMDGLLTDQELLQFLRTVEEVDPVDSTVINSVLDRFASERQQDRDTFGLTSDDLRDVYQHISETFNTSTKSSGFHQHLWRDLLQVLAIEPGARFISRENLFQLVVVAHSDGTDLELMALPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC43</accession>
    <name>A0A8K1CC43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC43"/>
    <dbReference type="OrthoDB" id="93842at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039589">
        <property type="entry name" value="TBCC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052:SF0">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="226" mass="25056" checksum="2177452849B4852E" modified="2022-08-03" version="1">MVTACHNCKIVMAPSSGIFCVDRCENMRISAIAGLMRVSNCLDSVISTYTPVPLIMSGENVGVQLGPYNSKYPGLKEQFAKAQIAYNAEFVGCWDSFLNLEDESDQTEREKAPISMQAPATFREICVPVKIKGQGPAERPFPLPPAFVETLRAQQETVETLRRLVTSDEFDLSTKRNMEIVIQMRFKEWLSTTGNVRQILDLVNIEKARNSTSAASTPLGDRTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCG4</accession>
    <name>A0A8K1CCG4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCG4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="49511" checksum="B9F9EE33A36C4492" modified="2022-08-03" version="1">MDDSASLDELVRFLEAPDDGLPDLIASDVSIAPLDVSFDPSLVDFGLHFVDHSNEADRDSSDNNGALVPTRAPGRRKKKNNSNRARDERRHEIAYLRKHVSELEQILAERQSRHGSNANHALVLAKTAMTKRLKVWKDIAEHQRAERLRVEEENAELKAALASQLQVKASLERIFNRRSISAGMRLCRFDTAKTETVRDFGPAVVQELIDSVNTSFDEIDAICQQIGITQSEFSYCDSRMREGEHGGLVLEVYQNKVLPFTAMAAGELVWKNFSQIMSQVPFRRFYERRNADAVVPEDMVIETMGMESRLNNTSLEIHGLQVLRRYVETDRVAILWSNVQDAVKFTDKPLEGRRFHHRGFLLLRKPKSLDPNEYCVLTTCYIIQPKWARVDDLTREMINFLKMEIAAGTAANHQHIENMLLRNAMAQHRAVVQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU0</accession>
    <name>A0A8K1CCU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="577"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="685"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="797"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="8">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="1359"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="846"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="846"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1640" mass="185265" checksum="945199DC59B5A466" modified="2022-08-03" version="1">MEVVPTPSTLPLLAVPSGDTAKFRKRDNELDELEEEALRVQIRQHLGTSLYVAKPPSPQARRRSYRDAESESTSMTAALTASLHTEAFDFSALSAFLTTPSRVVRCADLRKFLLRLLWVSDEDMEEEINEHDPKIIAGKKFLKGVEAFAMLTENELAQLVGLSELRSYKTGDVVVDDERDADGLYIVLTGTATRFTVVDAHTSEPHDESNEDQDDDDLNTEQDNMIRESFGYQEHFGTVISPTEAATMHARRATTVVATAELLECIWLPESVIRMLNVQSRMEYEFVLVLHNHRNQSETQHRQQEEIMLNLLRAGLHVTVLANTRHTTHCIVLLLSAPLWLLAREDKLLSMDRVAVDHAAATVDEGDDDYASHAETMTASDRIAAFASILTRSASDKPPGVGLRGVENNQDSIVRDVFPLHDPSMTDFILSTWFKESHSTSTKRLFLLRIKDYFGLRIAFFTAFVRLYNAALVYPVNVGCMLWVFWRWIDYRSYIQALGLYGLYVAFLWAPSFLKRWLRYQNSLLVEWNLVGTTEVEQPNPEFRDFVIETINVANDGEPPDYVQVKTYDHRRRWPKYAIFGVFCAASLVLLFIFVSFYVQWYIIAVMTPMCTDPRCPEFLDKPGGCESHCHYLFAQGKDYAFMQQISSCAAYCDLRRFDRGYYMCDEPLVGCFTTERGVVGTARWFYVLVQGIVLGLTLDIVFLAVFEAIASGFNRWENYATELENEKRFIEKIFLFNWVGYFYWFFLLAFVYVPYGARVQEWVRDHIDGGWVLTLNHNVRFSRYWIDGLITMDSAFVTPMIVTQALNLVINTFVPFLLRRAILRARESYHVRKDQLLLSLRQKTTTMRKTPESESSTVSNDGGADVTPSSTTEPWIPLADLSTLHRPDVGAMLAQREPIKAEHLDEAVRALFAAISTHDRHMDEICGGELHREDLDVYQRTSYDWLDRVTRNLEERGHLKGVWTTSSTTSSLHLALITHWQCRNYDYTADRILEESSMPIYSPFGDLLHLAIQFSYTIMFSVVWPFCCLCSFCRNFVALRFDAIKMTIDCKRAVPRRTVGIGSWFGAFLFEILIAQLAVPGLFVYVSGQLDAFFEDCTISKTRYGPDEQCVHPSTRLATFCTLENTGIALCFVVYLKKSDISRETSIKIVEHSRKVRHHLRKSIRMIGESVLVRVTNPTKASHTTATQRRSETEWGMAVSANNAMASVSSDPASFFSVDLSDLSDEPSRPGSPGRSTIASAATTSTLLRRRTTTATSDLAMVKAQLDTNGLSTATSTESSTEWREGTVAWVRNGRVKVNFSGGRQLSGGGLANAAMLQYNEHEMWLTPNDRYVLLEPTPVKVFSVGMSALLASKKFGRWTEATITGLDNRDRFGRELAHTPNEMHFRFIEAQNLRTHAIRNAALIDPYCVLTAGGFRHTTSVKRRTLNPIWDEDVVFPLSERELYGEIANIESLGSAAASASSSRHTSYAGLDKQSVSVTTATLHAAAAAVHPSASKEAGAGVGLGSPRRTLKLSVVNNDQVAMGECIGEVEIDLNQFRSGQKHRMLIPLSQKQKRHIWTLDAIQSVMRKQALGAGEYPMLGLPHILIEMQWIDTRLPTKVTVQLTTAQQRKELVLSRKFCETNLCYGIPSDKVVHGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD73</accession>
    <name>A0A8K1CD73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD73"/>
    <dbReference type="OrthoDB" id="206848at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056304">
        <property type="entry name" value="Lip-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24708">
        <property type="entry name" value="Lip_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424701" description="Lipase-like C-terminal domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase-like C-terminal" evidence="7">
        <location>
            <begin position="24"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="48120" checksum="554F203C4029156B" modified="2022-08-03" version="1">MQRFLVLLVTLVLTVGSQLASAANKYPIVLVHGLGGWGPSEFLGIPYWGTLQGNFQAKLKQEGYEVYVVGIGKVSTDWDRACELYAQIKGGRVDYGANHAAFHGHARYGRTYPGLFPKWGEVVNGQLQKVHIIGHSMGGTTMRMLTQLLNNGTKGASLQEDPASHPLFAGGKDWVHSLTGMAAPVKGSTLTDYLDVNLIETVIATTFGVLNALGNVTNQVYDIQLDQWGIKPKEAGESIEVYIKRVLASTMFKPGYTDNAGNSLSPAGATSQNKWVKTLPNVYHYTFVCEGTVDSRDLLLRKIAVPNKVVMNPIVQPLASLIGGRETVTRGYSEEWLPNDGFVPVTAQLGDGVAKVIDFNGTSVRGQWVRFETLKMDHLGLMGANPLIPVYNLFSAHAKILTNLPAHEALKSRRLEEAGEEVAHEADPQTVLSMQAALAPLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDC3</accession>
    <name>A0A8K1CDC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDC3"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="318"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="43572" checksum="38626BB6A7595A95" modified="2022-08-03" version="1">MRTASSLSENEGLMVHDHGVGMKILVMMSQEIADDVLATFPKLQDAVEQTATDTGSRWKQRRPKNGVNLFELEPNSGNDADVAHAFLATAELRCHVNEVLSVLVHQDSEEMDATVNSLGGRKVRGGGVYYQQLHLLESQLVNDVNTQPDAALFGVQTVVVRPKLSVRRSSKLRIGFSTCTIRFPKRDRAYHLMKTLPKRVHSRVVSESESGVLEGKHDHVATGWDIRLVNQAAYGSGNHTTRVIAHPYISAVPPSEFGRLHPASLSSSVLAQHRKSYASPDAERVASVLTKSLCEFETVIRRRRLGFQTFVSHAKEEAVDSPICLICRVTFSFFRRDHFCRICGHVVCGECSGMYDVEAPIGRVYKQRYCIACIRRVDACHFDDEDLVPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDG9</accession>
    <name>A0A8K1CDG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDG9"/>
    <dbReference type="OrthoDB" id="164487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="45816" checksum="AAC9D7F493C5BAEB" modified="2022-08-03" version="1">MAARQFDAAMLPKLDLTRGEQEAIQLEARAVIDRALVLEAEFRRRGGAINQKKWKEVMARDNFHVYKRRKSSRHGKFVLDDEIKLPELMSMRAHDDVSRRAWFQSFTNETDSTTSSRESVDDIEAPPIITCAGYVEGKLEDVIYGAYDGNEAEWKLRSAYLKDKLSEARILATIEGPTHEDPCRFLGIKWFSTEYPPGLGVFISKRDSLVIEAIGITTDSQGERHGYLVVHDYYDPRIPELTDYGIIRNKLSVCFLSRQVTPDRVAIYGCAFLDLGGNLPSSVAISIGALTLVSTANTVDASYNKKLVWLMNQQQAQRRMTKDQLALPRVSSCHSCHKIPRLRGLTPCCACAREFCSACAVERRLVVDAPTDHRDVTWRNLKFCFACILRAKELPAVHVARVTNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE08</accession>
    <name>A0A8K1CE08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE08"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="62497" checksum="5D838EFFEEF118CD" modified="2022-08-03" version="1">MFGQRTTLRSPTGGSESADSPLSAAFSATHTPSHAPTKLFQEADDGLFLHDDGALRSGGMPDLLSRDNIGLLVNYLCVGTVYGAFPKTIYPFLGYYLNMDGYQMSAAAVLVSLPWSFKMFVGILTDCFPIRGYRRRPYIVIGWAMCLLFLLVMAFLPVGDPYYIKGEIQKHREDIENRLVGNPDAPASGAKYILLMMGASLGYVIADVACDGVVVEFAQREPLSRRGHTQSMVYAARFAAQTVSTAIVGFCFNGQEYGGDFSFSLSFNWLMVIIACPAAIAIPSTWCFLPDDKAEGKSLAACATEMWEIAQQRAIWQIMAFNFFNALFYDMEAVPASIVQRDWANVEPINDTIFTVVAYLFMAVSVYITQRHFLNASWVGIILGTTVLCVLIDAVVSMLTIYDIVRSQWFYLGAPVLSYIPQGVRFIVSGYVTVEIASPGYEATTYGLITTVNSLASPFSTSISAQIDAYFDAHQDDIATDTPHVRNQVMYTYLIMYIFKLLSNLWLVLLPRQKLEAQFLRLKGGSSRTAAVVAFGVAAYALVWSVMINLLSIFKATACLKIAGGDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEA3</accession>
    <name>A0A8K1CEA3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEA3"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="506"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="402"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="610" mass="67783" checksum="93D61FCB957181DA" modified="2022-08-03" version="1">MLVQDGKDFGVRMAPDEYIGELKERINEKQKYPQNANDLTLYRAKSKETCPNDGVIHVLVIPPEPNASRPPLASELVEQLQRGFIASLEKKRKCDEEEAERVKKMKISSKVRVADDEYQLDALAQSTRVVKTPGLHSFWAGYGDFPESYFVRKEEVTFWQVVKRMLTSIDDDNWPRIILVGSSGVDVSFVECRGENEDDCYACVANLPEGTYWHQDYPSFPVVDAVTPCKAYRPGSDESEDVAYLHVTIQDKKTLKPHRLKQLNEAMNKNTQLSPLKRVYIVVGPNASMCETFTLHDASSIDTIVAMVGCFDPQLGVMEPSAFVRKLMEQALAAKKEGDLGREPPLVVVGEHVRRLAAQFGLDVACDEELETFQVTKEATKQWEKWHTRLSSAQDDETPHLDTVGAICLDPDGNVAAATSSGGILYKVPGRVGLAGCPRVGCDARNPVINTVGKLRSRRPQQGFAMTCSGRGEHFVRSNFTANLTQMLQSSGDLNEALRSAFEEAKDDNGDVPLEGGVLSLSIDPSVKESDDRQSTPPPERKRRRMHRTSEESTKEASSSVVSLGVAFTTPCMGVGFVHDRVKEPQVQILRQPKPGQANIVTHVSCWRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEP0</accession>
    <name>A0A8K1CEP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Xaa-Pro dipeptidase</fullName>
            <ecNumber evidence="10">3.4.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Imidodipeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Peptidase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Proline dipeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_009557</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Xaa-L-Pro dipeptide + H2O = an L-alpha-amino acid + L-proline</text>
            <dbReference type="Rhea" id="RHEA:76407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:195196"/>
            <dbReference type="EC" id="3.4.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.9" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEP0"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102009">
        <property type="term" value="F:proline dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000002">
        <property type="entry name" value="Xaa-Pro aminopeptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48480:SF2">
        <property type="entry name" value="PEPTIDASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="16">
        <location>
            <begin position="70"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW62064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="60344" checksum="6374C0D52EE1F71E" modified="2022-08-03" version="1">MSDNNVKSLLSATAAVTAAASIALLQKRRAPTYAQAWSNHKTNHHHHGLTEVGSNGHAATGDIDYELFPIDYAMHVQHRKKLVKQFLAAHPKAKTNSSAILLHGGSEVDRYDTDTQYAFRQESFFQYLFGIREPDCAAMIDLTTEQAVLFVPRQSAEWELWCGDRKPLTYFRTHYKVDAVYYVDELKTILQSNYGVEQLYVLKGKNTDSGLETVTTSTFEGIEDFSVDTKALHPVLVECRVIKSEKELELLRFVNQLSSNAHIEVMKTVRPGKMEFHAESSFLHHCYSYGGARLHAYTCICGSGHNASALHYGHAGAPNDKKLDDGDIFLNDMGAELHGYASDITCTFPVNGKFSDDQKMIYEGVLKAHDAVMAASKPGVSFIDMHLLSHRVLTQHLLEHGLFQNGTVDELMDHEISAYFYPHGLGHLMGLDVHDVGGVPPGTTRSTKKILAKLRCLRVLEKNMVLTIEPGCYFIEAQIHDVLKNPATAKFINKEMLTRFRNTGGVRIESDVIVTATGLENMTKVPRTVAEIEKVMQHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEV1</accession>
    <name>A0A8K1CEV1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_010978</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in transcriptional regulation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEV1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000097">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF23">
        <property type="entry name" value="ZINC FINGER PROTEIN 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="58"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="259"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="440"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW61915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="58309" checksum="2B225BBAA85F369C" modified="2022-08-03" version="1">MPMQMNAHHYESSGSLKHHAALVEPQHDDFGEVADSVHHHLLPHHPQHPHGAASMIAGHHHHHQPHHPPHHQSHYTPWSLSHVGHFGPEHDDEDPEDDDHGYEDEDSGFGGEHPVTPTGVAALATGQTGIEAKSRRVSAKNNTFVCPEVHCGKTFPRSFALRRHMRIHTGTKPYVCDFQGCSQRFNTSGNLSRHKRIHSGERPYPCVFTTCGKRFNTSTKLKRHMRIHFPEGQNVFQCVQPSCAFACDNYKEYVHHQRQHGNPVYAPPVGKHDGENVDDSNLPTPKGAGSKKSNKRAASRTTKVIKPRSEYVGPSANEIPERRLFGNAVGSSAPNGLSLLVKEAQRESDIDADYMDHRRPFVKSQHSTHDDRPRLPFPTEAFPSESIAASPMHNSSFGSTFSHGHHHRTSSYYDHPASSTSYGTTSSVFTSSSSSFPYLRGSGSENGYSHHSSYLTQDGNGSLHFPSSRDEDPEEYDSASSPTSAMRSHQQTDEVKYGYANASHHGVGPEFTGEELSAVLELMKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF60</accession>
    <name>A0A8K1CF60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF60"/>
    <dbReference type="OrthoDB" id="76714at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36241" checksum="55A0C12186C109E9" modified="2022-08-03" version="1">MAFGWNGKEYGGDLDRTMSFRTLMLVLAIFCIPVIGLTWLFVHEDKVAKPNFKEYINTLWEAVQSHAFYQVIAFNFFFNLFANQSYVANSPIQLYWVKASNLNYNISNLINNFVFAAMLAVTGKIGLGWNWRWMVGITAVLMVVIDAIFTMIVVWDVFRSQWFWLGGPIVEQVPYGVQFIISTYVVVELAGFGNEGACYGLLTTVTNLSSPFATTITKNIDGGFDVWNSDIMADTHHVRKDVTITIWIAYACKIFALVFLVLLPPQKKAVQELKLKGGSNKYIGALNVFYCMFALEWSIMTNLFAIFESSRCLKIVGGCKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFL7</accession>
    <name>A0A8K1CFL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_009813</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFL7"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF24">
        <property type="entry name" value="PHOSPHODIESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="14">
        <location>
            <begin position="66"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW62320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="497" mass="55596" checksum="E81F2A5104BF2638" modified="2022-08-03" version="1">MGVAEVIYTVRRRLALEILDLEPIPDPPPPRAEWPAWTSENASANQDVRLRVLSLNAWALPIAPKCTERAVEIANAIQEGYDIVTFQEIWHRRERNIIITRAEQAGYHYYHYFQPAVGFPLPLGAGAFGTGLLVVSKFPIVSAMYHPFSLSGRPYALHEADFVANKGVGLLRVQTPAGQFDLYVTHLIANYNYLGRPGPGDRYLAHRITQSYELARFINATNRNDLTVVCGDFNSPDDCLVLGIPRELVQLRDAFTDMNSHDGLTFATEDNIYSHGDHPMRMDYVLYKMTQQANDTPGWHLVGSDVFKGYFTDAKGQEFPLSDHFGVTAEFVFGSRPLPLKPCQQALGETSKEQSSPVAKNVPTCPTTTCMHCDELKAQTDGVKLTEDGYTRTVRLLQDIQQACLDGQAAAFFSRSAHLRRCAISAFLLLCLLVVHAIGLMSLSNWSWVAILLLVLTIIVQYVLAFFYITLELSSFMEMSNQVRLHLHAEQANQAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT9</accession>
    <name>A0A8K1CFT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT9"/>
    <dbReference type="OrthoDB" id="164026at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="622" mass="69953" checksum="E2BC82EF4EC93B2D" modified="2022-08-03" version="1">MRREAALRGVPTPVADDLRYNMWIPASVLTATFKDTEILTSLGQSSQPSVWMDNCVNGNIRDFKCIKNAGISFVCTDRFICQKLGGTELSICGKKFKVQTYSRYTHWYYVDLTRLPDETSDGEIYDWFAEQGAPPVYITPTNSIRGLHSRSRRVYFPTKTTPACFILPGEKPLRQIGFRAGFCVVNHRIRAYNQSKPPFLEALQTQRRELKKQEKNEKNQSKSKPAFSSSLQADIAKSSTEKKVKDGDDESMEGDSEYNPDDDEGGDGGDFPMSSSSEKSKSRGSSFDSDSDPHSDDEKDDGKVVVNPATIWRDVSKPPPNFPSPPDQRSEITFFQVLGQRHTLFPDAEIFSAKDNFKVKVLPVSQNSYPVFATVNPFEWIASGETDDLPPDVDILLTDDNKKLIASTVKMQKRAKELLDGARTAFDVNEMSLEALSNFLEKILSELDNTESADDTIAKIQAQPCFLRPILSKTVPANYKVLESKIVDHAYYRVVSERTKSKTNARSTFAEKLKILFADQVPSDAITALQKLVEDPDEFKQQLRLAEIDLCLQVLAPGIYFDPYKISAIVQQEVTRLSNSRWLLWDDATLELLLHSDFGTNLLKTKIPTQLAKAVTEARARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFV7</accession>
    <name>A0A8K1CFV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucosylceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFV7"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000109">
        <property type="entry name" value="Glucosylceramidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434297" description="Glucosylceramidase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="5">
        <location>
            <begin position="105"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="6">
        <location>
            <begin position="470"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="60798" checksum="7E16C269EEB5C75F" modified="2022-08-03" version="1">MLRSWSFLAVLALGFVANDNAVDAACNNFSTRFNKALNGVCVCTDASCDTVSNAYLTTPAAQLSVYTTSKAGDRLAPSTVAINTTKPTTSDFIIEPTVTYQKMIGFGGAFTDAAAINIYKLKTTSLQQKVLDAYYAKSGLQYTVARIPIASTDFSTSVYSYNPVVDDFDMKSFSIDVDRAPNSNKLNLIKRALSTTKRELSIFASSWAPPTWMTKENKTENCHVKGVPGEPYWKALALYYARFIEEYQKEGINIWGFTVQNEPGQPIIQPSAWQSLRLTPEEERDFIKKDLGPLLKQKFPNIKIIAMDDNKADIPDRMATFDDAEARKYIDGIGIHWYKNFDFFFFGLGGDYDKLANFHTKYPDIFILGTEACEGYLPAIIGTGVGVKLQEIDQIWYRAENYARDIIEDVANFAAGWTDWNLALDTTGGPNWAKNFVDAPIIVDEVSGTEFYKQPIYYIMGHLSKFIPTGSVRINLKSNSNKNWDNIHRAAFLTPEKRVVVVFCNRRSDPATITFQTPLQTSVTVTIPARATQTYIFQAAAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGJ3</accession>
    <name>A0A8K1CGJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGJ3"/>
    <dbReference type="OrthoDB" id="125769at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="7">
        <location>
            <begin position="158"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="45202" checksum="654B0BE656AFFB58" modified="2022-08-03" version="1">MGNLPLLSGTMQSDAIKAREASYFHTSRVSASFHPAPIAPFPFSPTDRPKLGRNRIINQSESSSSDSEDDTDSDSSAGGDAASEDTEGESDAEDSSTSERSCGASNSSLSDSEVDDFSATDDDNAPIRISSGAKWRFKSMNARPDLPVWQSDNIGIAALLIPITGITTMVLTEVLACANHFDCSKNYPTLSYAAEFKPEGYAFTIGMCSTAMLILATVALFHWFLRLRLMHPTVDRATVLITHGCLTAGAISAVSLFGLAVFDMGAYHDAHINFTVTFFIFAWVTMIAAQLARRLLLRDDKVASLSRAPSSVPWTIWNAMLRWKHMKTIEAYRLGWFFLLSGLTSTAMFGLLFLCVNGVWSNPLGFTAVQEAFFEAFAIVCQLLFMGTLSSELALLTRVVEYRDYQELERTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI27</accession>
    <name>A0A8K1CI27_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI27"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="36040" checksum="2C591591EA406C0C" modified="2022-08-03" version="1">MAAAIVDWQLAYAHVESAVRESVSEFPLPYATASAFGVCLQLLWAITFATWLASIITLNYSHIDRLWSITPFLYVWHFAYRAYLDDGAQWNDRLVLMGVLTTAWGVRLSYNFGRKGGYNLKEEDYRWAVLRETMHPILFQILNAVHITLFQHVLLFLTVFPAYVAYVFRSTPLNQVDYLATGLFLAALTLETVADQQQWVFYQTKHALLAKKATLTGDYKVGFNRSGMFAYSRHPNYVGELSVWCAFYVFSVACTSVTWNPSIIGAVLLILLIHSSTDFTESITLGKYPEYKTYQQQVSRLVPWFPAKATKDRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI50</accession>
    <name>A0A8K1CI50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI50"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="6">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="33741" checksum="A47B9FF0A5B12587" modified="2022-08-03" version="1">MSRLSTDPRMPQVNDLVISLPIALVLGVLRCTVPKFFQSIGRVVLSPSKRIVPFRVDRFSTSLFKLIYFWGISTLGYLVMKDEKWFPTSLGGSGEAAECVRVFNEPPSVPLKFYVLVQFAYQVHNLIFMGFIRPFYPGTLEFVTHDLVAMLLIASTYLVNYVPLAALVGFLNDACDAIQYIYRVVVDSDRRLLVVPVYLAFLPAWIYTRLYVFPTEFIYNTLHNLARENPDVALGYLYPLNALLIALQAMQVHWFWLFLRKAPQIFSTTTTATVKKIKRGRHSRRIIMYGLYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI74</accession>
    <name>A0A8K1CI74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat and coiled-coil-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI74"/>
    <dbReference type="OrthoDB" id="164838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="56975" checksum="AF96F6536F7B7CA9" modified="2022-08-03" version="1">MMVDGPVEWTEAEGSRLDVLQQAYNVRLKIVALPKGSTVLLTRFDDGNDGEPRLVGDDIATQKIDELPLHSDDVAWRSYLHVAWSAHSDQKQWLAIASSSHVEVWEVSIADSAIQASLKGSAKMDRIRTLCWNPRLPVVMMNSDTKNVLIEVTHERIIEIELALVSRPSSQIVKRCAWSPCGLTLARAFKKDIEFYSWSKLEDILRERPIHSDFRVDQGAEARFLDAEPSRIGPIASISQLSASVCLLTTELTLSLDEPASMGLSAPTTSSIELPKANAHDTSSNVIDLTSLRITTSSRSSLLSILDNRPDPSPVLTKVQTPPQSARVILVVKDTNGQWRQASNIEIPKLTLPDRLRVEGMRVVIGSTLSNVLLVAHLDHDTRSAWSLAISGELELSNGYTCRGIHLAQTSPFVQVATTEKAKRTFFSASPGSQRIHLSKLKLPRRPTKERYPPVAPPTATPTASQHTANSIGLEDVLNRLAALQTQMISRFDRIDEQLASMCSRLDHLEATQSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIA8</accession>
    <name>A0A8K1CIA8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIA8"/>
    <dbReference type="OrthoDB" id="73371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="449" mass="53130" checksum="E1C9893601DC74BB" modified="2022-08-03" version="1">MADVMDGWGQKPWNVSEEMWKRKAKSLEEQYQRLLSDHQDLRLEKAKVMGELRVLQRYKETAEDMINKEVATRKIEHKEKLSASTKLEQYMKKYERECEKVSTLERENAFLVEQVSNMKGETEKRLDLLRELEDTQKRNARQKEKIREMEIVSIEHENNILEMKEKIQKLKRKVETTEEALADRNEECKNLSVRLAAVESAWEASRGQNKSALHELKKKETLSKELENVKTETKQANFRIHALDLEVETAQSKLRQKERLVEELRETNAQLKREVNRLTSKLDDLGSNLAVVNEIVAEKDKEIKRKEEMIRCKKTEVRCLAKIDDSSKERIEELVRQVSDLQQQLLDTQKDYLNKVKKDEVWREKQRSKDRAEIIRDMEDLHKPRRCKNCSETFTTKSNTSLSCSYHPGRYVGRQYPLEGYHWSCCQKRDLSSRPCKFAGRHTESKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIZ4</accession>
    <name>A0A8K1CIZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIZ4"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953">
        <property type="entry name" value="KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="3">
        <location>
            <begin position="400"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="611" mass="67914" checksum="A091749C2A17C799" modified="2022-08-03" version="1">MGVERLAQNVSALSMEPSVASTAPSSPAYVQKADYRLYSDKYEGLLLDLDAQIAKGFQVVGVHFQALRSSVFGLVSMTLAWEDTPDSIWVIPLITYQLSKFFSVLLRLLTTEKVVKVFHGVRWVAHELQVKKFHLGGHQLQKCLDLQIYYEEMVDKSVRDADLLRVAYHWNQTSPYHLVKNRAESSLTDDVAKHTAVVATFLRDCYRSHVVHHTNFGMLPVLYQMTGRRWRFSMQYGDQELVWFDKSSGYQHRSLECLGEAGIAPQLKSTCELEPLLAVLPERYRQAILDISGIKDGLVDICLDVGRTAHVCRKDERVALSSDGQQFVVTKAEIDEIIENLGGEYKIGDDNRAGIDCQLHRISVMRSKSGEIYGMTMRVGRALEQASNFLLDLLMASEYKMKSILLLGHPGSGKTTLIRDIARCVSESGENVCIVDTSNEIGGDGLIPHSCVGWARRMMVRSLDAQASVMIECVQNHTVSTLIIDEIGRKAEVNSAGTVKQRGPRIIASAHGDFRSLIKNQDLKGLIGGVQNVVVGDSAAKASNKQSKVQAQRSGNPVFDVIVELDHVNRGVCRIIPDVARAVDDVLKGEEYDVMTRKQCVGVPGIQIVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK58</accession>
    <name>A0A8K1CK58_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heat shock protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK58"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000135">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000021">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="618"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="630"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="652" mass="71089" checksum="8977849B11DE3E2A" modified="2022-08-03" version="1">MAQAVSGYSVGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNAHNTVFDAKRLIGRKFSDPIVQADIKHWPFTVSPGAGDKPQITVQFKGESKTFQPEEISSMVLTKMKEVSEAFIGKEVKNAVITVPAYFNDSQRQATKDAGAIAGMNVLRIINEPTAAAIAYGLDKKGGERNVLIFDLGGGTFDVSLLSIEEGIFEVKATAGDTHLGGEDFDNRLVDHFVAEFKRKHRKDLTSNQRALRRLRTACERAKRTLSSSAQAYIEIDSLFDGVDFNSTITRARFEDMCGDYFRKTMEPVEKVLRDAKLSKSQVHEVVLVGGSTRIPKVQQLLSDFFNGKEPCKSINPDEAVAFGATVQAAILSGNDQSEKLQDLLLLDVTPLSLGLETAGGVMTTLISRNTTVPTKKTQTFSTYADNQPGVLIQVFEGERSMTRDNNLLGKFNLDGIPPMPRGVPQIDVTFDIDANGILNVSAVEKSTGKENKITITNDKGRLSQADIDRMVSEAEKYKAEDEANKIRIEAKNGLENYAYNLRNTLNDEKLKSQIPDDDRQSIDDKVTEVINWLDAHQSAEKEEFEAKQKELEGVANPILQKMYASAGAAGGMPGGMPGAPDAGAAPSAGGDQGPKIEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL46</accession>
    <name>A0A8K1CL46_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL46"/>
    <dbReference type="OrthoDB" id="96355at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="29392" checksum="47201C79BCC7BE1F" modified="2022-08-03" version="1">MSGDQERRNGDEGAPFEMDDVRDRQEGERGRQVSDVYMTRAEETPVMATESTWSFVQMNMTLLPIARPLPVTICHRFQEGVLGRKPRTPNQKLHHRVLRNASNISPRRQYEGLAARRGSTSSTTESDPGVQEFPRALPQRTISAPVDIPRRCGKRKSDFEDTSYHASSSWQAPSRLEIEVDDLRVRSHSEDMTMQDVNGWSESPDFTLVRSASTSSAFAQRGSYKGKRILELQDEERRLHPDDRVALPSPSKRSRRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLM2</accession>
    <name>A0A8K1CLM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLM2"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="275"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="400" mass="43608" checksum="A4BF065E1591FAE3" modified="2022-08-03" version="1">MALLDRFASVYLVFCIGLTAIAAVPPPIVILSSADASHKCAGVAISSLDVLIQSRCILENNILTSTFLIDEYSRSDSSNECVDDESSPSEDNKSIPLASIVAVPLNNSSTASSGENAPSLHVVTLRAPLDSIAPATLLIQTPYLRAHEIDESAMLITVDLSTLQTSRIDSVVYMNGSLCDRRVCLLPTEVNARDVNQESNHWSFLFKHFASHDGYWLLGVGGSPITDEDGVWSFKWLPQSLLETSFTDLNISGVKTSKTVSKEDYGKPPMSTIPEDIPFIAGIRASSKDTNSFCTGVLITKRLVLTAAHCIERGTIRYVALTANNYPNKKEYGEIIRVSHTIMPRSCSVKTSARGRTYSNNMMLIQLEHASSRTPIRLINETLKTMGDAVKNVKNATDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLS9</accession>
    <name>A0A8K1CLS9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLS9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="46983" checksum="059A8630C21077A4" modified="2022-08-03" version="1">MVSTKHIPTWRRASATTARTSEQTRQATPVAPLLSPETRPLPPTNQDASVNKAHALTAVVATIKAAYDKLKSFMMKYRKRFTTADEVMAMQNEDVDAAVPAFYIEKVAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYIEKLAMQNEDVDAAVPAFYVQKSMVPEDSLSLSGSRRVTSRARSFEGSTSCQTSVNPKPYRRAYSDVQPRVNSHRNAPRTIDKAPEWRTHSMSPTLRRENAEYQRRLAAVKPRVYQHLTVPANESRLKPRTIITCDLLQRPAWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLT1</accession>
    <name>A0A8K1CLT1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLT1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451011" evidence="2">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="13547" checksum="1714311DDA838895" modified="2022-08-03" version="1">MKVVLAIAATCVAMMVYTQPALAQDLDDIEARGHALRQLEDMEPTLGETIVFPTEDLERRYGDDRRDYRRDYRRDDRRDDRRDRRRDYRDDRRDDRRDRRRDDRRGRWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLY6</accession>
    <name>A0A8K1CLY6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLY6"/>
    <dbReference type="OrthoDB" id="128901at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="343" mass="38820" checksum="F414B2C0186FB3AA" modified="2022-08-03" version="1">MAESPRQIHRIHAPPHVARLPCVPFEWQFEGGENFYVRKCYNWFYSAVEKILLKKGERCVTITGTPGIGKSVFYAYFCDRFRQQHPDICVIAMSFSETIVTEAVVFMPGDKPKSTAVPGCIEPLVDETSSEAERQGIEVLFLCDGAPARQRRDGDMVVFTTPDPTWLRHVRKNANTYYMPVWTLVELQEAARALGLPLTDEQVETSYEIFGGDARFCLKTRIPHEFIEQGERVVAGREFPDRDDLMASIQSITTPMQLRNLLSLNDCSHANSRLVHYVPDQHGRKAATCFASPFVLQKLTEQVLKMARYDSVKLKQVLAVAVNADDLIERALAMNTTEPTRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM84</accession>
    <name>A0A8K1CM84_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2 9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 9"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM84"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000082">
        <property type="entry name" value="DNA-directed RNA polymerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="10">
        <location>
            <begin position="147"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="994" mass="113363" checksum="BD9281435C6B55BE" modified="2022-08-03" version="1">MPTTRGLLRLAIAKSQAARRGLHVQVRAPQQSRRTASAVLNQLRMKSSLPSPQPSTESLPTNAFGNVLEVADWAKHSYLIEPRPALQSTTFSPLLERENIAEEELLQRAFMSDADVDKWLEHYEIPAAELAKCTTEEEVKELRRLYARQLRLECSIYEMAIRRREASMMSVNMLGLSSKTNAAKSLILNWMVPASEYIEQEQRKLRASRHSLDSNTYGPAFLMLNADVLAATGMNVMLNQCLMETRGTKFIKLALAMGKAVQEEIIEQKEKRGDKYLLKLTQNLKSDFLIKKVKEYHDDVGLWDKRVNLKVGAALIDCIQRSCFVPDGLLQESEGQGAAAPAFVHDYVFERNRRAGVIRVDKQILNTVLSTNPSANVLPWTARYLPMLVPPKRWEGVANGGYLRLHTKIMRQRDSAWQMDCVKRGEMDALLKSLNLLAEVPWVVNNEVLDVVLKIWESGGGFGDLPQRENLELPEWREEYEHDNVKRAQYEKMVRKIHQRNQELHSLRCDTLYKLQVAEEFKHEKAIYFPYNMDFRGRVYPIPPNLNHLGSDLSRSLLVFRDRKPLGKNGVRWLKIHLANVFGVDKCSFDERVEFTDANLEKVFASAADPLGNGEHNGWWKDADYPFLALGVCFELKRALESPNPEEYMSNVPVHQDGSCNGLQHYAALGRDLSGGEQVNLMPAPRPSDVYSGVATQVMRKVEQDAALELPEFIPPMEDFVEGESKYERARKQGIRDLWTKKRRKKYAQFLLGTISRKVVKQTVMTSVYGVTYIGARKQISARLEEVFLEKGQLMDSKLEDQIYHASCYAAEVTMESMGDLFTSARAIMEWLGDCALKVAQNGQAMSWITPLGLPVVQPYRKSGTQQVRTKVQHVLLVLSEQLPVSTGRQKSAFPPNFVHSLDSTHMLMTAMRCLEEDQIAFAAVHDSYWTHACTVDVMNQRLREEFVNLYEQPLLENLQDELRLRFPATKFKELPQTGDLDLNVVKDSPYFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CME7</accession>
    <name>A0A8K1CME7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CME7"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="651"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="729" mass="80858" checksum="433EFC4330CCE2CF" modified="2022-08-03" version="1">MGCCSKKPVEVAGTNYEQKTGVAPATTRKCRDVLCCLFFLVFWVGMIIVAIVGLMNGKPQRLLYGSDYNGTTCGTGDMKDKPLTFYPRINEDLIEQASKKDVSPTDFDFYGVCVATCPQQLTYFCNYEFEVDLASDSSLKTDADRNAAREKEAKKLMGEKHCWFVALASQKVFYRCIQMTETSSTSTEVCVYPGDESQYYDTVDGVKVPNSKCEVKKVRTISDATGPAQENPIYDKLQTAAAVVGRAIGDIEHTWEIILAFGGGAALVLGFVFIFMMKYCAGCFVWIALWAFVLMLLLFALMASTKAGIIKDSDISKLSSTLADAGIVAASQNGLQVPENLRASEDKKKVYAVVAYVFYALSGVAFLLVCFFQKKIRITVGIIKEASRAIQRLPLLVFFPLIPFVMILVLFIYSAIIGAFIYSSAELKVDKLGASASTMLSKVDSNLAMRILLGYHFFGFLWTNQLINAISMCTIAGAICRYYWSREKNAAEMGRFPVMYSFKNCFRYHFGSLAFGSFIIAVVQFIRAILMYIDHQTQDIQRSNLVVKVLMKIVQCCLWCFEKCLKFLSKNAYIMIAMKGRSFCSGAKDAFKTIFNNVGQIATVSMVSFLLLSAAKIAITMACAVIMFAYLEKNDDKYGIGGEKEISSPMAPIVLTILLAWFVASTFLGVYEMAIDTILLCFCEDKEINKATGQYYMSDKLKKFVASVPVSKIQHAEEQPAGNANDEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMX4</accession>
    <name>A0A8K1CMX4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMX4"/>
    <dbReference type="OrthoDB" id="10251089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08061">
        <property type="entry name" value="MPN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17055">
        <property type="entry name" value="Ubl_AtNPL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007717">
        <property type="entry name" value="NPL4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024682">
        <property type="entry name" value="Npl4_Ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05021">
        <property type="entry name" value="NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11543">
        <property type="entry name" value="UN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47899" checksum="77E6F0A3A292EB09" modified="2022-08-03" version="1">MLLRVQSKNGIWRVTDLSALSTVADIKHWIEKEHAIAAATQEIALDKQRSRVAQDHQTLQELRLGHGDMVYMEYDGDLITTGGRVGRKIAADGTVTHVTYHDRVDKNSFRPGLKALRDMKMHWTLDEFMRMDAQFEYKISAQKSAHVSKVILDGASCNDFQSYLRQFAFQQSRCGWLYGSVNEETKEVTVDFIYEPPQHGDPYGFEVFDDPNADKVDAVAAALGREKVGWVFSHLPREDESFHFSAHEIMMAAQLQADAGGKESLFVTLKVTLDKEGQASFEAFQVSDQCVEMYSSGAIIDNEQNPKACAVHSTFTALVEAKAATEIDNNFFLCVVPVSMHDSGLKSEFPKLNREGVAPSRAALKQQLQKYRSDPYVKRISDFQLLVFLCDFLDAQTDIPSICQSVRDAAIPLDSGYPLLIDSVAGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN85</accession>
    <name>A0A8K1CN85_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008347</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN85"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="56"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="56"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="59"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="33521" checksum="30EA13A186A90E0D" modified="2022-08-03" version="1">MKSPVRMSRRQSWEASVKSEPYSRLEADWHQQARDVSPPREDESDSDSGDEDQDPNQVQGKGTWTRDEHKRFLEAIKIYVNGPWKLVAEYVGTRTVRQTMTHAQKYRQKAARRIRGLRTKQAIMRMHCGHEVSEESMAQERMRSMLGQSRHAYLPPELCTSFLQSAGPISPCTSDTPSFSMMDEYARLSTHSSTSPSPSYDASFDAAVGNVLEDVLDIKVKPTPFDMQPPLRISTSYSNELNGYVSDSNASDASDCSSVLAPLHNFGELEISTDLSNSPTLEECANVLLDVLFDETSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPE4</accession>
    <name>A0A8K1CPE4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPE4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="100" mass="11407" checksum="D1471C55C274F208" modified="2022-08-03" version="1">MGKRKRGNEEFDSKLGEVFLFGGEARAEKAAKDLSSNLKLTRRINDILRKEVSKQGKFVPEVASELDQALHEVEILLQEAERILYQDVRKIASDFKKSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQK2</accession>
    <name>A0A8K1CQK2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQK2"/>
    <dbReference type="OrthoDB" id="543560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="111" mass="12566" checksum="58CFB786EA63FA00" modified="2022-08-03" version="1">MGKKQQNKQQQQEQKPVPEKKGQAQQQQQKQAAPAPAKEAPVQQEKKGGKKGGKKYVKREAPEANKPNAKREKKGVKDRVKTQRERGQAGIGSDFKTWKSDAEMVLRQQFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRF5</accession>
    <name>A0A8K1CRF5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRF5"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051943">
        <property type="entry name" value="TRAFAC_Dynamin-like_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43681:SF1">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43681">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="2">
        <location>
            <begin position="91"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="560" mass="62044" checksum="360424304F8CF845" modified="2022-08-03" version="1">MSMLLRRARVATTAVARPRGLTGHASLKPLSTLSETIAPKALLQDDEKWIRLMQKTSQLEAKVLLPLNERILGPLDRKHKEEKLPSLPFVFLLGNHSSGKSTFINYLLQREVQSTGVAPTDDGFTIIAPGTEDIEQDGPALVGDPDLGFSGLRGFGPALIQRTQLKVRKGINANFMLVDSPGMIDSPKSLHAPGSYYGVPPALRGSGPGGYYDQQQASSSNWRGTGGAPHSLTYRGTGESSDRGYEFPDVVRWYAERADVILLFFDPDKPGTTGETLSILTSSLVGMDHKLHIVLNKVDQFKKIHDFARAYGSLCWNLSKVIPLKDLPRIYTMCIPVKQNDNGERLTENGLGTSLRDLDAMREEVVNEVIRAPERRVDNLITNLYDSSRMLQMHASIFEDIRQRYSSEKWRRLALVATTLVGGNALAASAIFSGAPVEFAGGLSVLSFLVSSGLVFNNSKVLQQLQLDLLHEDSLTDQFRRRYGRQLAEGDEYVLSLWKRVLPALQVSMHTLGFNNLPKLKNAELEAIEKILAKEIPELRRQSAPSDTSLAHKVAKMFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG8</accession>
    <name>A0A8K1CRG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Intron-binding protein aquarius N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG8"/>
    <dbReference type="OrthoDB" id="1879at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="2">
        <location>
            <begin position="38"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="3">
        <location>
            <begin position="556"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1206" mass="133868" checksum="BD3E6A67072A209A" modified="2022-08-03" version="1">MARAAPAAKATASKDDKHTLDELLKQIEKASKPDETLKQIVVIYERFLYAASLENVVSSLNALIASEYLEKRVWPLWTHVAKTKSTADRKAWLLTILLLVIRSEQTASSSWTFFTTQATADVHAWDAFVQTLLDSAHSEHARVSTITATKKPASHSDVWTLREKTALLSFLSKCYAHLDVAPIATHFLKLVSLPVWSALSSTQRELEFEQYPKLARHWRKLMGDTETKEESGKDKSKRRKVTDGTESHVSTHEKAFIDSLVQEFVAFIATSDVKTLNKAGEDVVDASLRYVATSLVLWTDILGQLPTRRFLLALLRRRQVLPQLRQSPLIQHWLEFRSASEQTALRQQIQDLELMLQFAIDPQTGKSLTSFQEQKEAALELVQTFQRTVFEHFRDTPVEALAILPVSAIQHAETFREQLSALVRADRGAVEDLGVRLGVFADKTEASALTVDLLVRCLVDTYALPSKSSSASEQLFPTEIEIWRDDLTDTSSTVYTASPSALFPVLALPKLGLQYLNLADFLRRNATLSRHLVSQSMRSDLESAIRSMDAVRSLARNGETVFRGFSQRAVPLLTAFSIMKVDKPAIGETVPSLVVAQFDVELDTQHDITAFDRIQPRELVYLVTIRPLKDEASEAMGYNSTTADESSTGHFAEDFGVMYVRCAEVLEVLDEDDVVLHVDDHPQGKGRKRAFKVALDGEQYKKDLEDGQLGAYEYTNLLVRRNTRTHHSRAVLETIASTLKEPEQVLPSWLYDLVLGYGDPAAATYSSLAKSQRHTSVTIPLLDLFVDGTHAVSTCGANNVTLVDENNKPLEASEASAPFTLVEDLVKNTTVLKAHRGASNDQMKVLTKAQVTAVKHGVSEGLTLVQGAHTATQDVVTSILQTVYRSTPTNEKILVVTQTQDAVKSLLTSLEAAHKVDIANIVALTSSAKTEDTTWSIQGRVGLLLQRRLYLLQQVDALAKWMERLDAKYAGLGVSASYSSDNALFFYRYYLKALLDAAKTTTSVQDTALRSYYVEKQQNEPMDASVLHAFAAEIEGFFGELERLQSFELLHTPRQRADAYLIQHARVLVLTAEDAAIQYRSLAKLRLSVKSVVALEASCAREIETFLPLLLTTTPSSQSIQSGLKRLVLVSDNESASKQKEEDVLTRYAGFSDSLLSRLLRLGVQSVTVDAAEGTVSATETKATKKPAPPTTKKTPTKTTPSKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRT3</accession>
    <name>A0A8K1CRT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011162</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="545"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="667"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1087"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1121"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1163"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1327"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="50"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="749"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1353" mass="150491" checksum="41BF495AB3EB316A" modified="2022-08-03" version="1">MSTTGPSSPASAPPSPAKSPIMKLSPEEFHDSVATTLQKATMKPIPQIDVRLHGVSITVNLAQEAKHRRIGGRILPKCEAQLPSSKNILNNISAMFLPGTITLVLGQPGSGKSSLMKILSGRFQLGRDVKLSGDITYNGIKRDEVMKRLPQLVAYIDQHDRHLPTLTVNETFEFAHECNGGKHLATTEKDRFTKGTPDDNQVALELVEEISRVMPQVIVQQLGLETCQNTVVGNAMLRGVSGGQRKRVTTGEMLFGMKQVLVMDEISTGLDSASTFDIVKTFRSLAKRLNKTIIISLLQPSPEVFDLFDDVLILNEGDVIYHGPRDQAVTYFRDMGLICPPRRDVADFLLDIGTREQLQYHESGRDSIPTDPRALADAFCQSSIYRKNFDALNTPVSKALLQNDHEFMDSRKPFRQSIIHNLWALFKRELLVASRNRTFIYSRLFMVVLMGLMNGSTFYDINPAMAQLLMGTLFGTVMFMSMGQISELPTFFAGRDVFYKQRGSNFIRSSTYVISFQLSKIPLSVVEAIVFGTFIYWLCGFVKDAAAYCMFMFLLFLSNMTFASYFFFLSTICKDIHIGKPLSMLSIGIFVVFAGFIVSKDQLPDYFVWIYWLDPIAWAIRALAVNQYRHKTFAGCMFEGQDYCMLTGYDSMGEYALSLFGVPSEKYWVGAAIAYLIGLTCVCMTMSTFTLEYKRYETHSSGGQTVTSTDVYDQIERLSILHNSSKVIPVEQEGEAPIQRKYTVPPVTLAFKDLWYSVLDPAKKKKGDMIDLLKGVTGYAAPGTMTALMGSSGAGKTTLMDVIAGRKTGGKIRGQILLNGHEVTKKVIQRCTGYCEQMDIHCESATVREALTFSAFLRQPAEVSDKDKLATVKEVTDILDLRSLLDKSIHGRSTEQLKRITIAVELCAKPSVLFLDEPTSGLDARSAKSIMEGVRKVAQSGRTIVCTIHQPSTEIFTLFDRLLLLKTGGQTVFHGNLGEDCANLIEYFESLSGTTKIPASYNPATWMLECIGAGVGNTAGLTTDFAALYKESSLSKVVDDDMAKPGVITPLPGSEPISFKHQYAATHATQMKFVVKRFFAMYWRTKSYTLTGLVMAVVLSLLFGGIFTGSEFATYQGVNSAIGIIFLASFFLSAVSFNSAIPIACEERVSFYREQAAQMYHPLWYFMGSTLAELPYVLSRSFVFAAIFYPFVGFRGAEEGTLFGLHLFLMVLMQTYLGQLFAYALPSMEVAALFGVLFNSISGNYMGFNPPAAAIPKGYQWLYYIIPPRYAYANLVAVVFTKCSSPGGSDMGCKPLLNAPLVLGKLTIKEYVEEMFRMRHDQILRNLLVLIGCIVFFRLLALLALRYINHQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRW0</accession>
    <name>A0A8K1CRW0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRW0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="59468" checksum="553E76A583055D2C" modified="2022-08-03" version="1">MLFVNCAEYDYLSSPPGFRVQVSQDCKGYDLVLVIGVTRPKHFQHKKLRLYLARNANGEWLQNDQNLSRFLSKEVDTQYSLLPLGIPLSDVFRDLVWDEKQVHILLREVEPPTSFLQHEQALLEEVLETSREVTHLPKHGEFLRLFDWSDADCGTFKDMTEVQAVMGDFIPARLYVCQEMLCTLKNVKDTYAGDLDGGFRVSRFIIIGSLSTGKSCLVALICMYLAAKHSRPIVWRGRTPHGPVIRLFYQKIVYEWNDRTGREYTLVVDGTKVVVPWFFLNGMTEESIKRNQGIDSYTVLATSSPFLGYSDEAMVRCVLPFWQKSDLDSVGSYLNLSTNEIDERYFVSGGSLWAFLSDQGRSVIRAEAIKFGHPHFEAFSCGFGIYESDFDDDSPRPGSRHDSDVNTVLRMYSVDDINDTTAYVTSNRWKRCVTSRFAMQCLAKLGSPEHVSRLMPLIASTDDSLTQDLVFVYQFHETVFRDRVLRVHRQRYASIEAEPFQMVWNNATTKNKLTRIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSH9</accession>
    <name>A0A8K1CSH9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005887</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSH9"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000343">
        <property type="entry name" value="Ras family gtpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="170"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="23250" checksum="CA6506174129462A" modified="2022-08-03" version="1">MSSKEYKLVVLGSGGVGKSALTIRLVTDNFLEDYDPTIEDSYRKLSTIDGDQVVLDILDTAGQEEYTSMQDQWMREGNGFLLVYSITSRSSFDDIATFKDKILRAKDVDNVPIVLVGNKCDLEGQRQVSSSEGKALAQRWGCAFMETSAKERIYNEECFFQVVREIRKSERPKQVAQPVVNDQSKKNKKKDKKKDKKKDGGLCSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSU6</accession>
    <name>A0A8K1CSU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DREV methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSU6"/>
    <dbReference type="OrthoDB" id="199041at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106370">
        <property type="term" value="F:protein-L-histidine N-pros-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007884">
        <property type="entry name" value="METL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890">
        <property type="entry name" value="DREV PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890:SF0">
        <property type="entry name" value="PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05219">
        <property type="entry name" value="DREV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33213" checksum="04E4CD68FA69125D" modified="2022-08-03" version="1">MKSWVRRASQQARSLSYNGPPPLDYHVRMNRLDPALQRAFVQLDCDEETQEFLNTCNGGSFFEAMASSVLGMFYSLTDTNGMIGRGQMFVLSKAQIQQLLHREERIGGSLLDIGAGDGNVTEAIASLVDHVRTTEVSPPMVKNLNSRGFNCAETGDLDHPHVLQGQPYNIISLMNVLDRADKPLTMLRQIRSMLHPENGLFLLAVVLPFHAFVEVGTRRVDPSEMLPMSGGLCTQGASFEDSASVLLRNVLQPAGFQLVQFSRVPYLCRGDLQQPYYVLSDAIFVLRVANSDETSSDTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSW9</accession>
    <name>A0A8K1CSW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSW9"/>
    <dbReference type="OrthoDB" id="432686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="373" mass="41200" checksum="90CD5A42CF64115B" modified="2022-08-03" version="1">MATTGYKLFTPLTLGKDLTLKNRVVVSPMTRARADKYTRTPNADNVLYYQQRAGAGLIITEAAAVSEQGHGWFGAPALYTQEHADGWKKVVDAVHAKGGKIFLQLWHMGRQSHPSFNAKGEVVAPSAIAVSQGQIRDAKGEHATYQLPRALETREIPAVIDDYRKSAELAKQVGFDGVEVHGANGYLVDTFLQSVSNKRTDQYGGSIENRARFLLELVDALKTVYPSDRVAVRLSPNGGYAEMGSQDNAETYTYVFQQLRQHNLAYLALLDGFGFGYHDKDDLLTVSDAKKHFQGHVIATNSYTRDIAEGVVRSGAADAVCFGRLYISNPDLAERFEHDWPLNADASYADYWDANQGSNGYTTYPAYTTPEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT15</accession>
    <name>A0A8K1CT15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007783</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT15"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="94"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="485" mass="53540" checksum="0B1821A14BAC2035" modified="2022-08-03" version="1">MLRRFVIISVVVVLVVVGVIVAIVLATHSSSTANQKVENKGRDSKKPSKSVREQGGLKVSSALSSSGSGSDGSEEAEPIDETDPRTETYSVTALAIGDWGRTVAKDGGSCCQRRNNFTVLDYNAMEYTATLLGLAAATLEPKPSVVIGHGDNFYWTGLQSVNDQAYRFQETFETKYADESLRGIPWINVMGNHDYGGASFVCSNGDVPAMCGSSQELLQHLNQKFTLQSTYVSPNDNRWLMPARFFVHSIQDPANASMVIDIFNLDTNDADTHGARQICCQCYGYSGGDDSQCEDVTRGHQYCAGGDTGMYDDCMKQLKTWGMESREKLVEAAKASTATWKLVNTHYSPYNHFAPDQADEWRQLLKGLGINVFFYGHTHGEKHDYAKFRTHFIENGAGGGIQNESPSGIPPYAEDYVTNLWAAGHYPYGIFSLRISPNWLQVQFLTFDETWVMAKELSASRVGGIAVKHCWYIPRHGGRGRSCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTD2</accession>
    <name>A0A8K1CTD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTD2"/>
    <dbReference type="OrthoDB" id="168256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="29907" checksum="6B2EAEB966E9EB68" modified="2022-08-03" version="1">MESSRGFDLPPVLKPDVEKRVLHVFTYLRQHERKARLARKIAELQGLGNGDEKQNEAEHLAPAVEVLVEELEDVKEERKETVYAQLEPSLDSIRAAVQAEIEELQKTINFRDFESTGLITATDLHSALRALNHTVSKADVQWMIWEVDDDQDGSLDWEEFRGSFVRCIVDRQGLEPNQLFCLILFLLCDTDNSLALSPADVRIELQRIPGTEYLISKLLKAFKVKDEQRKYLFTQFVSLVLNDLPTVPIGSSHVLTKYEGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUM5</accession>
    <name>A0A8K1CUM5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUM5"/>
    <dbReference type="OrthoDB" id="10265294at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004846">
        <property type="entry name" value="PRK06197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="324" mass="35399" checksum="9453774A10BCB462" modified="2022-08-03" version="1">MSASDAVPDKWDASHIPSLTNKLAIVTGANSGIGYEAALELARKGAHVVLACRHEGRGNEAVTKIEEELKTTPDAGKVEFMQLDVSDQSSVKRFVTEFKKTHDRLDMLINNAGILGIPYTETVDGFEAQMGTNHLGHFTLTAQLFDVLKASPPSRIVNVSSVAHRTALIYDEDKPMISKEKYEPWLAYSNTKLANLLFTMELTRRCEANGVTGVSAIACHPGFATSNLPTAAVQTQSWLMSWVYRIGSSIPIYQTAAMGALPTLYAATGVNAKSGQFIGPNGFRNWWGHPMVEEPYPAAKSASAGRKLWEWSEHVTGVQFLVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBV0</accession>
    <name>A0A8K1FBV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006501</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBV0"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="11">
        <location>
            <begin position="110"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="379" mass="40999" checksum="98F1F0FA0EBE24EC" modified="2022-08-03" version="1">MGCIHSRDAIEAALRSSQENPEALRASLNQMLKVPSAKPSAGSSHRDVFSIFADHGLMLEQEEVAAASYVLSPCSASGSVFSTATTASDTERSHMTHGPLDQYVASLDVTYGSYSDKGMRKANEDRKVCVSEVVRGEPVAYFGVYDGHNGANVADHLTQNLHISVFDRLKESNDMRSAIENAFSETDDYIFKKQMDSGSTALSMMVRGRDLIIASVGDSQAVLSTGGKARPMSVLHTPDHPFEKERILSAKGVVVNGRIFGLLGVSRSFGDNDFKTSRGDFKARFEGDLVIATPDIVEHTISDNDDFMVLACDGLYEVMQPQQVVDFVRAKLALHGGVQHACEELVSYAISIGSTDNVSAVVVCFNQVVKEEPVKSTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCN1</accession>
    <name>A0A8K1FCN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCN1"/>
    <dbReference type="OrthoDB" id="73352at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="99751" checksum="BBA1DC6A6CCDB3C4" modified="2022-08-03" version="1">MDGGHASGPPTPATAAAAAAAEAKKTGRPSHPLWAHFHRGEKRNRYHYHAFCSYCVERYGLEHVAPTRGVSIDMLRHLEKCTNCPRKVVETIKEICGQRDAIRFDRYGKKKQDTEALTPPPAATSPPVARNAAMATAFQQAQQQLQRMLMQPQGVTVDGTTAFDPSTLQLNGNGVRPGDMISDPSSPSGGPLKRLRTDMYTNGSTNATMTEEAKVALLKLAVAAGLPAESFYNRDFQELLRVIMPVFNTTASLDTALTSILDPGFLRDSASRLAAFQLDRVKEGMLNSTIKGGLTLSVHCWSTLDLQNLVAFNLVNSNGDCACVSLVDMHDTVVATSQLETPTFSATPYTSDQLATKIEEVLQHLQEQNISVMGIVADTAIALNAARRVCAADPSRRSLLVVPCFSRLLSVLAGAILTHDTFVPVVSNMIEVASYFMNAKLLTALKTISGDSLACCVLPHRENWYSFAECLMRLLEYRDSIVRLCLQDEFPVPQALKELVLRDDQAFWARLGELQLCLVPLRESYSVFFQQVRTVQPNDKSQPTIDVLEDDLSAAHGLTLAHVMYQLARMTQQYSAISVTHHLLQHIAQEMKHHIDSMWRRYELPVMVLAFVFNFHLDTALLNMHLAPTTWEAIAQSFQIYYQRWFGQVEAANEDAEKAPETMLVTNNRVEEILDAFKLNQFPFDTETTGDYIDVSSFYSFVSDSHPEICALCCRMYALSLVSANVTRIVHGVGYVPSVARTTREPEAVELLLHVGFASSLRRHSILAEATDSPLSLLGGFEGMIDYPADALIECEETWQAFAEDWRGFVAQELEMDEFENITQLTSTQDPASALLAVKVPVNELFVETLTAMTVTLEGGDEASATDAEPMDVSAGPDQPAGSADGQNTRSSDSTVVSHPILSVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD56</accession>
    <name>A0A8K1FD56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD56"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="132" mass="14941" checksum="B4ECE734CF8F1C41" modified="2022-08-03" version="1">MSNVNLLMELPSTTPVLTRKRTFAIMTLQCTRLSKKTRVDHSPRDLDTCGLSPETLAYLAENPLDDDVPPHPVLKRQEAVYQVEADDHSADHEMWMQRLCRPSVMTARGMHTSRIGQSFKPSIAPKSLNRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDP9</accession>
    <name>A0A8K1FDP9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDP9"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="325"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="481" mass="53329" checksum="C8D3DFBCB4098DD5" modified="2022-08-03" version="1">MMMETKTAFAALCEAIGEEDGATRSNSVVYLSAEWYEPIDAVVLPVLRRLAAVEEGVMEVIHLSRRGLDSIPTEDGLILVDETTFRDLCRKLGATHLPTCFLVDWKAQQLGHGPSEVARELKEFVEAVHSSPKVTSWPSISSELSPLDAENETLITLRTNALETFENGDFVTAAKQFMQVLSRCSDCTKSNFNLAIILQTLGEIYFAVSHMLRVVETNDQDAVAHTVLRTVLYPEEPKLVLAGYESIVSQHPEHVRAAHSLATLRGEAETAAPDYVQQVFDDLAETFEDKLVNHLEYRVPWQLVDALQRDGALSSRNEHTDFKVVDLGCGTGLCGRLLRPFSSHIVGIDLSPLMIDKTRQSGHYDELETADIVPFLEAQPDNSLDLVISADVWIYVGSLDAIYPLVAQKLKPGAWFAFSVEVLVDQEGFRLASSGRFKHSENYITSLAAQHGFTVRLSEAITVRKESGEPIPGRIYVLQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEB9</accession>
    <name>A0A8K1FEB9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEB9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="39886" checksum="410CF6DE25E5C888" modified="2022-08-03" version="1">MYRDPSRLQELNKTSTIEPMEASPANPLTVVIPTQKFHVLRVVSKNGWNCFDLSCGPFPLTFELKTVGDVVNTVYEANRGHRVFADTSPHELKFYGSIRAFHSGEKPLKHAESRLVLEHRHSHEFVIVVPSNQRHQQLVWYELLDSTGYHYLSTPLASMPCTKASTVTSFLAALCREHSAIMAGVDYEKDLVAYPNRALHALKEPLEGSASPHPYGQNSLDPLIVVVHSRKMWYTLYGEDKQPYFGSSPSFLPVSNEVKTVEGLLHGIISANFAYLANVDVIPQLQLYKTEIELCTYREPMHCSSSTLLGGLTEYDAFAVVVPTRFFWYSVLDIDGNNCCGIEPTSIPLKKRHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP9</accession>
    <name>A0A8K1FEP9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000822</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP9"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000731">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000007">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000006">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035448438" description="beta-glucosidase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="8">
        <location>
            <begin position="672"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="790" mass="85968" checksum="E4071311CDAF57FB" modified="2022-08-03" version="1">MLKSWIKAICFTALALAIVPSGALTDSAESRAAKIVDGFSVDEVLGQMTQINIAVLLNSQGGLDEDKVRQFAKLHVGSYLGSPQTNGPIGGNYSSSVDEWRKMITRIQDIHKEEGNGHPIIYGIDSVHGANFILNTTIFGHQINGGASFNPDLVRKMGEITGRDTAAAGISWTFGPILELSQNPLWPRTYETFGEDPYLVSVMGSNVIKGIQANKDVAACMKHFVGYSKTPTGHDRDGVTLSDFDLLNYFMPPFIAATQAGVKSAMENYISINGVPVVASSKILRDLLRRDLGFEGFVVTDFAEIYNLNSFHRVAKSLSEAVRMSLTQTSIDMSMVAMDSNFITYAKDMLKDFPEYYDRLKESARRIIKTKIELGLYETPVPGAKYVKDVGSSAHRDVALDLARESIVLLKNQDNTLPLSTSDTVFLTGHSADDRGNLCGGWSLRWPGYSGNSMFPNGISVKDGFQKLASISSVSYFNGLTVNGTYTADDLAKAKELASKAKYTVAVIGEATYAEKSGDLDDLALPIGQINYVKELASTGTKVIVVLVGGRPRLLSGLPSNVHAVINALLPGELGGQAIAEIIYGKVNPSGRLPITYPKDPANIMIPYNRRVTTLCADQTPCKMEWDFGTGLSYTTFSYSAVKLSKTKVSGKNDKVKASVTVTNTGKVKGKETVMLFLIQPFRSISVPEAKQLKKFEKIELAPGKSKTVEFELNYKDWSVFDPQIGKGFVRSAEDGDFVVAIKPETDCDVYNSAGITNPLCAKFTLESSWVPFRLNAPEQTGISIVSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFK9</accession>
    <name>A0A8K1FFK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFK9"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="218"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="294"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="43496" checksum="A0C572C82702B9D8" modified="2022-08-03" version="1">MDTPRLSAPNTPLRSETSALDTQEWLKTALIPATDKLAVSWMKVEEKQLALTDQIRKSLLSSDDAMRFGLERIQQLNENLSMLLDDSTDAMQEVMQQLRRIPERKSEVSAFDEYFATTASVADSDWDRESTLTSLTNATTPSEMLPSEPMDDASIHQLLVTNSRRLLDEQQTPRGDAPSTPAFSPSVTPRGTHSRKRKHERTTKKRRTLLENQRLAAYTALQVLERRRPSGQRTQEYLIKWDGGIEPTWHTLSRCPEHAKELVLAFIRLQQSKRMRSVQHEVKQEDGTHEGDLYTVDTIVDDRIRVGKKEYYVRWDGYDSSENTWEPAEKLRREVASVVDEYERKLARNARRRHQRATMRSNESKVHQARGSMATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFT7</accession>
    <name>A0A8K1FFT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Purple acid phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009518</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 6">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFT7"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778:SF7">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="665"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="11">
        <location>
            <begin position="206"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="9">
        <location>
            <begin position="352"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="10">
        <location>
            <begin position="581"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="701"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="721" mass="80299" checksum="374493F355FF7DFB" modified="2022-08-03" version="1">MGIRTAIPMMETTLLYEPLAPSHVKPVPRKRKLPLRTTMVTLVLSAVVSSIVIVVFTRVRLADSDELNQTTSLHDDVSVVSSQPRVIKSFNVSNAVINHLDKVNVSFAYGEPFPSSLDIAGDWIGVYCLENTTTTTTTIIDGNASLTMPVTDYIDRRDTRGAIESTIEFGPLVNMRCSLQFKLVTSDNVVLASSTVVRFREGPTEPLQVHLSMGNKASEMRVMWTSAALPVGTAQVRYGTHPNALDRVASATNTTYDASDMCAEPATTRGPRAFRDPGVMYDALMTDLQANETYYYQVGGNQTSWSQVRQFQLPPPVAGMSVPSEDDKPLDLFVFGDLMTATDATSDFRLAGGCGTTMQLIERDLNQGQDKYAALIHVGDLSYSSGKTYVWDQFAALIEPVASRIPYMVSIGNHDFGYLEGRGVKDDRAPPHPAFEADGTHGHDAYGECGVPSERRFHMPENGDGIWWYSMEIGLTHHVVLSGEHDFTAGSPMNTWLLADLQSVDRSKTPWLFVHIHRSLYCSVAFNGDYERSLLFRDHLEALFAEYHVDVVFSGHYHSYERTCPVYDEACYYGENGEAEAPVHIMVGSGGANVDTFGHYSVGWSEFARMAYGYGRVHVHNATHMHFEFVANDVGDVQDEAWIVSSHDWPSDRLRWRRYFLNPSLASRIIAGVGVLLLIGLWIRLHMRRRRADLSFESVKKKEDVATEATQRPSSTDRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFU1</accession>
    <name>A0A8K1FFU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ER membrane protein complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFU1"/>
    <dbReference type="OrthoDB" id="1894652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22209">
        <property type="entry name" value="EMC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451257" description="ER membrane protein complex subunit 10" evidence="2">
        <location>
            <begin position="24"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30822" checksum="F634F33B0DD40A77" modified="2022-08-03" version="1">MMLRHVWAALLLVCVVLASIAHADPREVESAEFKDEFGEEYDDRLARGNELDQRLEFELEHNIPSKGAAFSKRGRVEIVFSASSVKPKVTFLDLPVLAETDIRHLETLLRKNQHYTLRVRSDPENPDSAYVVTSIPMCMLAGTRMREDLTFHLSDSGKLLAVEYLTPYVSASTCAEYQKRELKNVKFAASASVLKPQNGPSPPKTISAKQKKAPKVVKNPVKDEEGEQPAEESQSFLRRYWYIILPLVVMSLFGSDPGPQGAPTGGAPAGGAGGGARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH45</accession>
    <name>A0A8K1FH45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiamine phosphate synthase/TenI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH45"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0784">Thiamine biosynthesis</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="3">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="24881" checksum="52DA9DDED42C45D1" modified="2022-08-03" version="1">MRRPWLVLLVPAREVGVKTVYEAIKAAVVTGAVDVLQLRATEGDEEREVKKAGSQLNRLLQSQQGTRLLVNCPSMELAAGVGAHGWHVKERELSVKGVEGRIRDAKMRHLSVGVSVHSVESALLAAQYDVGYLQVGTMFPTASHPEKDQAEGPQLLQAIRDTQKNGSIMPPLIAVGGIQTQEHVDQVLTAGADGIAVIRGILTASDPTEATLAYRQWMDQHERQSNNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHG6</accession>
    <name>A0A8K1FHG6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHG6"/>
    <dbReference type="OrthoDB" id="66085at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="163" mass="18099" checksum="B26CF91EBCC12644" modified="2022-08-03" version="1">MLPSSSSPVPFHTTVRTESAYELKTEAARRNDHIKTPYKAPSDYCHRPESPATTWSTPGTDFLAKFCLPDTQELRRRIALDQEGFFTDGSPSSPVKLTAATSLVKSDQPGVRIKSSTRPGSPTQAFESRVPHTSRKSANTSLRLEKIVDQDGLLPQLHDIRQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHV2</accession>
    <name>A0A8K1FHV2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHV2"/>
    <dbReference type="OrthoDB" id="155196at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="48111" checksum="0EA215EF9C5A45C7" modified="2022-08-03" version="1">MPRATIRSPSIPTLSLTPEEEARVENEATALLNQTLQIEREFFANDGEVDEKHWKLVKNRDSFCIYKERHLEVDEQDESLYVESSGGSEGQSAAIDSDDIIASKKRAHVPMIVSTGHVEGSLDDAVFGFAAGDILSWRLRTIYMKDMFTDGKIVKTMHLPTEEEPLNYFCIKWFVTEFPAVVNAFVNPRDFLVAEAAGIKVDEQGKRFGYYIIHDYEHSTIGRLDEYGVCRCSMSMCFIVREVVPGMVHVFSRGFVDPRGDFKPSIAAAISARAMSALTKTVEASYSKKMVWLMGQQERERQEKQRRDRSLSPDLIHADTCAACAKSPGFLKAKLEACRLCRANYCSRCTVERSLVIDMSGPDVTKRTFTFCAGCVLKAKQLAPHEVAVEAVRQAQSCGDSTVVFPRASDASSVELYTLSSSHSSNSNSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX5</accession>
    <name>A0A8K1FHX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHX5"/>
    <dbReference type="OrthoDB" id="25576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02619">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899">
        <property type="entry name" value="PAPAIN FAMILY CYSTEINE PROTEASE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899:SF1">
        <property type="entry name" value="PEPTIDASE C1A PAPAIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="69421" checksum="2A0D27505BBE72B3" modified="2022-08-03" version="1">MQDSAYGTVAYPQEHDGFLHSRETKKQQMPWGKIAVGAAIGLAGLGYCASLQSTLSAQQQLLVKMQQQLDAMHTSMQAKDTAAAVVSNSAMRHRGQLPHKFVIDHVTPLKTQDNRGTCWDFASVGVLENSYRAQGIQHGWLKENEYVPISEQAYGAEILRLCTGPPGSPQHAACFLPGGGIYRNSTDGGDATELYYLVNGLKDSTFPESICPYNPDPGNDTVCDGLTKEKRASNPLRFTLKKLESYYQEPQIKDALLRHRQAMAFTTPMPYITHYYPCVGDFAKDERCNPESNACTLCPPELALTTCCIPVTGGENYNMHGEFIAHSGMTLEGGHVMTLVGYNDLYRTKDGLTGGYIIKNSWWDGIHPALGPKHARGSHSIKYWLQEISDWEERTMCPNSYRPDNWYQCGQDGEVIHARSNSGARVPLPLTRRENVTGIEECLSEETKLYAETNIQPLHLECTDEAYCKTGAEYTYFARNATEWGDRMQVMCFLEYNTASKVASELCLPPMLMEKIAYIFSPVADEVRENDHDVCGFYFYPYEVQQQYNSNFGNFYVNHFDIEWHASSYLANKEDYPEYDYSEVEKSTKKQKTYGPFVGPFPFARVVPSDAWKQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIF1</accession>
    <name>A0A8K1FIF1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIF1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315">
        <property type="entry name" value="U BOX DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315:SF7">
        <property type="entry name" value="U-BOX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="632" mass="69997" checksum="7C05284F4E74DD9B" modified="2022-08-03" version="1">MEGVEAVSELLQQGRHIVQTILNADGEFCVTVKRQLDQLELVRSLLEQGKVQPSIAMHKYLHEFEAQLTRFATYQSQSKWYRTCHKSEMERHFRECDVRFQSVTHACGLTADKLILETNKPSHRATSKEQKAASKTRERQPSTCSTVSSSTTELFSSNVKTSGPQAALKSTPFNGDGSHFDVIDQLLSCGNDTSQQRKALSSLDQWIAMHSDENPLKIAHLRVLRPLLQELHEDSEDRRANARNALQIMTKHDKSKALVANNSVIHELVLIMDAETTYAKRIAAADALEVIALASYTSNFNLTAIIPALAQLIRSGNDDQKYRAAKALFKLAHKTTLLTVMCARSCIHLLASLLRTGTFQQCYYAMKTLRSFSKHASARIAVVTALGKDVPTLINEIELAKRDSTAFHSLLMLSVLAIDDDDRRRIGDEGAIPLLLHLIQFSHSDRVRSSAALGLCFVVEVRENQERLLQSDGLDVLIFALKKGGSRQLKAVANVFRSFAVAASADYIQQMIDAGVVSAILKQLDTSPIAEVKCEVASALCVLLRRHDGAVNERVLHELEQMNGAAILARVLRDAESGDARVYTQAMLQDILSASSVAGKALSEQFDLQSQLLSTSEDDLPWLITNIVEELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIS8</accession>
    <name>A0A8K1FIS8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIS8"/>
    <dbReference type="OrthoDB" id="271745at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="126" mass="13198" checksum="2C2EEF18EDBDDA0F" modified="2022-08-03" version="1">MLRAKVVPELLRQIVGEGVDAAMLLTLDGALMGSVGSTDGVDHKVIGAIAAHTWGEYLHSSKEVAPESDLEALLVELERGRLALASAGKGFLVVAYSRGDAPAGLLKTKVETLGEYLASSLDQIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ39</accession>
    <name>A0A8K1FJ39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ39"/>
    <dbReference type="OrthoDB" id="164487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46295" checksum="CAC7153B20E2B570" modified="2022-08-03" version="1">MTRHPPPVDTLQLSREEEQVVFQQASAFLQKTLALETEFRRQGAKVDTREWKEVSAVDDFFVYKQRKAVRRGRDLATSRDFSRSDEIAAPELMSMRDDMSKKQWRVDTEGGLESTAPSTSSSASGGSPDEVYVPQMLCTGSLEGKLEDFMYGIYDGNDLAWRLRSAYLKDKLADSRILATIRAPNHDDPFRFLGIKWFATEYPGFVGTFAQDRETLVLEAMGMAKDENGESYGYYLMHDFTHPSIPIRTDSGGIRQKFNVCFIHRQVGPDRILEYGRGYVDPGGNMSVSKSISTAAASFSSVTNAVDAAYNKKLTWVMATQRNRRAGSTATASSSSVCQSCHKASHGVLSRSLLECDACGQFFCGKCIVERKLVVDIHTTHLHPRALPFCFGCVLRAKQLSSYDVARMTNIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ65</accession>
    <name>A0A8K1FJ65_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_008387</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ65"/>
    <dbReference type="OrthoDB" id="1914176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000017">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor 30 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013989">
        <property type="entry name" value="Dev_and_cell_death_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10539">
        <property type="entry name" value="Dev_Cell_Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00767">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51222">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="12">
        <location>
            <begin position="242"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="DCD" evidence="13">
        <location>
            <begin position="430"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="187"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="577"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="648"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="611"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW65745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="745" mass="81769" checksum="8F31A32B27B4EE11" modified="2022-08-03" version="1">MVLGLVLRDQEERQLVFDFEALLPDDVDMGDDRDENGKKDFKRGTVVCRHWLRGLCMKGDNCEFLHQYDMSKMPECRWGMECQVPECPFRHVPDEERVECAFYKQGFCSHGPNCRYRHIKLAREECPETADFSLQSKVADEENVKRRKAQPVNEFYKIAICKHWEKMGTCPFGDDCHFAHGEKELRPFPKGERDARHGGPGGPGAPGGGNGMHGGMGASKGPESAAPTGPPPVVLPDEGKFCKYFIVPSFSYHNVAHGVHFNQWSLPRELQQTLKFASETSDDVFLYFTVSSSKHFQGVARLVPGALIQAGSEEGEDLSMSLVPYQSDNKGAWSGAFGIEWLRICECPWERLMEYENQNLAVNECSNGQELEPEVGQAIMRLIFNSPQIQLHYRSVEDEQKLPGGAEELATRRREAAESIFGGPAPKWKVTTPGFVFACNHTNIDEVFGRMLMGLGSEHEAVATKSITPGTPLFLVNMADRHILGVFEAISPAVVNLMPGAFSHGPQQPSPLPVQVRFVVALNAPAINSAEPQIKAIFGDRGIQVGPLALQATQRLADVFSERCAGPMFNQPPPMNMNMGMPPGRGGNGPGPDQAAAASGPPPFRRPSATGSAGSRDPSSSSAFLEKMLVGIEPDNEFGVTRRIIGPGGSHMKRISQEAGGGAKIKVRGRGSGSKESTEDEANEPLMIIVSAENERSFRIACELTGQLLDNIHHDYQVFRQRQQQRGGGDRGDRGDRGGYGGYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJF2</accession>
    <name>A0A8K1FJF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJF2"/>
    <dbReference type="OrthoDB" id="121607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="7">
        <location>
            <begin position="589"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="651"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="84305" checksum="B5553F005FBA8CD2" modified="2022-08-03" version="1">MAPQRHRYTKCVLFTGQRANKSNERVVCRYCSEAESPAWAYENALLCNTKKLVKNHLRRCRHFHAAMASGKEELIVFSEDEAEESRVLLAEQNKRKLLSMSGGGGGATTAVPSFGVRNKRYKGDGATTSHERAMGTSTSYQRDASAVPDRDVLERLLLNATLANGWSFDWVKNRASAQLFQHAWTNAPLPSSAALRGRILKTAGAKEQEQLTLAVEKEKLGSTLVLDSWRCVEQSNTVGVIITSSGAEVLLWDRKEVGDVAAFQQEMEQRNFVVRTLGELATNSVQVVAVMSDSSSPYLKARQWIRQQRRDVMYLPCFAHQLNALASDVFRLVPQYESVMITAMYAILWINRSQDLIGQLDRKRQQMGIPVVPVTIPQSFDWDSLRSVTSNLLISKDALKIVCRDAEITSMFPVSERVAQSIEDEDGFWRVLLDVDRLLFCFSRWHSTVKLDQSRLHCVPLIMHSIATTLQQISRPETTSLLKRLDDRWSEWEHPLMILAVVLNPALGWAHVQTNTCGVTVMRLGCWARYYFQAYFSQSPRTLATELLEFVEGDKFWCSSASVGLFTVASLQDQDAEAHAGSDEALRSKMQCRVVQYWKSCSADCPDLSRLALRIFSVAITSAATEDLFSDNGIASDQLNPSQQLAAMRVRARSRYDQRRNDNGSDQSNANVEEASTEEGQTKSGRALVAERTRVDARLKSLLNRWANQDVVDRPVSSGNENEAINSLYSTIHPADDAYSKYPITSLFPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJX2</accession>
    <name>A0A8K1FJX2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJX2"/>
    <dbReference type="OrthoDB" id="125599at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="714" mass="79406" checksum="D0F58C1FE9223B42" modified="2022-08-03" version="1">MAFATFVQRLLRGSTDEGPLNGFVAGVIPRRQTHKEDDTSLQCMVRTIALLLWALWVRERAALCQSLLLNEAVKSEEVTEQVAICALQLYVLAPFRNGSHDLVGLQLTLLEAAIARLGHSNGATATTIALVISWGFTSDRLGARHLKRLKAIRAALQSRRYVWHESEAPIEFDELERLVELRRYEMTRLVRAALGQSDDHSPLRSPDARRGWTRATEVDTLVTCCADADFQRLAWSLLDKRFIVRPQTHDTTPQQLQRALHARSSTIEGQVSRHEVLMLLQTQRLELEQQVRRLTGAVNDALQVNHQPPPQVEVAETQTELVSADKPADTGMAKSSGRRQYRIRDLQVDPLETTTKPAPSAVLRKSASSAKVLKLLQLRKQQSQSTETLKRHQSVMIPPPDARVDVDDTKASQQELGISRRQHSERVLPLRYDAVEASSSSTMRLLSTSTTRTVSMQPRAFLNEARQARNGDRFQQKALHQAEVSLTSASTQCTEMRTMSAQTEIASVPTPSTSAEGTAQRIEHAPVASQTTETNEAAVQCGFTEQVKRSTSTPAATASILQRFPVVVDLSAPSRKPYVHVAKLEQTPPRDRPVERVITSSNVAEPIDTDVKSTDSLAPVEMVTHDDAEAIDTTAKVDDERRQQLRRTYQSHYAPIKVTTRRATTTNGDAGKSSSLSSLRADMEQMKRKLVALESCAQEIEDDFKHSQQVGLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJZ3</accession>
    <name>A0A8K1FJZ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJZ3"/>
    <dbReference type="OrthoDB" id="126245at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="198" mass="22949" checksum="E8664D726BC2EB32" modified="2022-08-03" version="1">MTISSRVHSSLFTSTELIRLPPTVLQHYEERQMIHGKHQVPVRRVNLWSREEHDRFLQGLELYPQGPWKLIAAMVGTKTTRQTMTHAQKYRQKINRRQKMQCILNNARSKRDNHVDAYVMTSLEPLPRDDLELVPLPVPCPPAAPALQVATPKQVYDDFTIMHNVHSPQEVTQVVECPFFDAELDELLSDLEPLPLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK66</accession>
    <name>A0A8K1FK66_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK66"/>
    <dbReference type="OrthoDB" id="443932at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899">
        <property type="entry name" value="DOMAIN OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899:SF2">
        <property type="entry name" value="FCP1 HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="25833" checksum="59C153FDE82C3F96" modified="2022-08-03" version="1">MAVHPESNNNELVEHEQRSPTEPIIILDWDDTLLPNTHLAILGFTDESACFALSEESTRELEQLAERVVAFLTVCVKLGRCHIITNGHHGWVQRSCKRFMPSVLPLLEHVTITSARAKYEAKYPRCPVEWKIAAFSDVFRKLEANDEDLGLLSSPPQQVIAFGDSPHDRSAIQYVGKRTNFLQVKSIKLLENPTMQQIQKQLSLMGGFMPQLCSHAESLDLVISANMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKZ2</accession>
    <name>A0A8K1FKZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium-dependent phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC34A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKZ2"/>
    <dbReference type="OrthoDB" id="67833at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037997">
        <property type="entry name" value="Na_Pi_symport"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="57218" checksum="1C303D67F2D71270" modified="2022-08-03" version="1">MKAMAAGSASRSRSSTEEGDTDQFALTMSPIQFILTYENLQEAAEEEAYEHQTTRRKVVSGVFYAVLAIAALYFLIIGIKFIGDGFTLVLSCGAQSIFDFTDNPVAALSIGTITTAIIHSSSTVTSVTVAAVGAGGMSMRQGAYIIMGANIGTCVTCMMVAFGQISDRRRFQRAMGAAAVHDIYNIVSVVIMFPLEVIAHPLEKLSMTMANWKSSRGAFTSPIDFVVNPLAALVVKVDKKRFNTVAAGKEECHPDISLVIGGAFEHASMDDRSIGAIVLSIGILFLIVALMALSRMLSRVFLGSTKRAVFKVLDYNGYLNIFLGTAITFGVHSSTVVTSLLTPLAGLGVVTLEQVYPLVIGANLGTTATALLVSLVTESDDAVAIALVHFWFNVFGIVLFYPIPITRMVVLKPAKSFADASAAWPAAAVIYMIAFFLIIPGIFLGLATMCTSSNSALVINGYVSVTSVIVGLALFLTWYYCYGGRRRWHQTLEQKRVDHEIRKYGGNIGMPSFVDDETSIYELSDRHQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL99</accession>
    <name>A0A8K1FL99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Choline/carnitine acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL99"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF67">
        <property type="entry name" value="PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="610" mass="69443" checksum="971D533022103393" modified="2022-08-03" version="1">MSKPSERTFQYQDELPPLPLPPLEQTLERYIKSCEPLLSEQELEHTKAVCHDFLHGVGPQLQAILQERADSERNWIEEWWETFAYLQPRYPSAININWYGVLPGNWGPRDMSQTEAATIFTHAILKFRKALLEETYPPEKLMGSPLCMHTYSRMFNTCIIPGEECDEMKSYPHDAKHIIVLRNNCIWAVQVFDDKGEELPFADILRQMEIVREEATGLFDLERYPPVSVLTSDNRTNWAKARNHILTLDETNRQSLDLVERALFCIALDESSASTYDEIARNCLLGDGRNRWYDKPFTLIIHENGRGGLNGNHTWADALVVVRAFDFCIKYVNENFKAKFADRSSLVPKTDIRPQRLQWVLDNTAYTAIEVASAAVGKLIHASDLTSLQFNHYGNALLKRYKLTPDFFMQLAIQLAHYKMHKRVPAVYETAHTRLFYHGRTETIRSLSNDSLAFVKTMESSAANGEKWDSLLKAINTHKETLKNSLTAQGVDRHLMGLYIVSEMSGITPRPSLFSDKAYDLSKKFLISTSNISGGPGSVPIWGGFSAMYTEGYGVCYALQPDRINVSITAYHACEETSAAEFKRHLESALLDMAELCLSRNVIYVGQSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMB9</accession>
    <name>A0A8K1FMB9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001351</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMB9"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
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    <sequence length="627" mass="67021" checksum="D3D245B96C5F811C" modified="2022-08-03" version="1">MEQPKEAALALKGLASGVTKDTLMAMFRTYGPVQRIALAGQGTAHVVFASRRSADRAAIATNGARVGGQAITVSKVGKFEKSARPCRSFQQGKCRKGDECKYLHVGEAGAAVKPAAATVPKVQTTPKADGPRPCQFFAMGQCRRGEDCQFLHETPAVAKKAAPAAKKTPAAKAKTEKKAKNQQSGQGRTCVECEQADSAVWQCVQCENALYCDDCNAAVHRPKVLRSHERTKLPPVVTKPKNPTCEECEKNESTVQCEDCGVPYCAACDSSVHQFKSLRSHKRTGLTSDEKPAKAAPVKKTETKAKPAAPVTAYIDSVPKFDLLSESESSEDEESDNEDAEPAVAPHAVTTTTEDSESEDVEMESAPAAPISYVNSVPKFELSSDSESSDDEDEKPAPIKKAPVNTELSSESESDDEDDKPAPLKTTPAPRAKAPVPVDVSSESSDDDFEDERPATPASAKPAPAKKIEAKPATVTVSSESSSESESDDDDEKPVVKAAPVAAKKRPAPSASSSDSDSSSDDEDEKPVAKQPRVTTTPARSSSNPPPPPPRRGQPERKPGISSGSSHTLVKKIEEYYESDNTEVMHLDPNLNGFERLLAHDCAERLGLQHVSVGLGLERHITISRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMH7</accession>
    <name>A0A8K1FMH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009044</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="TMW64877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:calmodulin binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:spindle organization"/>
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        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
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    </dbReference>
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        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
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        <property type="entry name" value="WW_DOMAIN_2"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="1136"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="1316"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="134"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1298"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="802"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="951"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="158"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1298"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1346" mass="155860" checksum="F90012308D213286" modified="2022-08-03" version="1">MDASRASTPPPSVEDMEDGRRQKAMIAAQLGLTLEEYEALDAAFGTTPEEDDEDSMTARYHTIFSQYDVDGSGAISPEELRSLLKAAGEDMDDAELAKVIEQADTDGDGEIGFDEFMDLMRARKRLLHVAKTMGIHGTGPGMQTRKGGIKAPSHGKSKSSATSSSPSPLSSSSPLPPLKLASVQSKKHLQQFNRHFSRPTPTCLRPGAQVDMTQLRRELAIAEYGLQELNSKVREDVHWVQQNCPVRSLKAQIYCHRWGMEKVQQLFSRLQSQTISRAYQKWKAFLMYERNKLKANLFLKCKGSQKMTEIMNKWKRKTLRRRFTKWKIECEIEARNEVQSAAIEIQRVMRGKLARLWRWREKRRLAATTIQALVRGHLARCTCARMRRDKLEHEAACILQRCYRGYNGKRVAKALFKVQRETLAARRVQRGFRNHQRRVLLRTIQRAKLEHDSAIQLQCCMRSYLARKERRRRILHQQRVQSSIVIQRHTRGLLARRLVNEKKRRLTAALTIQTRYRAYRSRWEVYHMRLNKAQREQRQLEYAAAIRIQTKWRSTHARQQYIQKKTQLREAQKLLAFRRLASALRIQCLFRGYRARRQAQRLRYEKLKWMNFTVMNRSALKIQAFWRGYHGRLASQLRLQAKRALEFEEQEAARRIQSIARGKLARGELNRRQEHRQYMLTTQQKQAKAALMIQKVVRGKRARKLTSKVRQEHADQAKAALDRLIRQTKARAAIKIQCCVRRFLARMRYWKRRHEAKRKKLAEEMRLSREHAAIVIQCAMRRAKARRLLLQRRRDFERRISLMASEKAYDEIERLRQEQEAELAQLRVQFLMQQSQAEKESVKLRQQLEAQREEEAERREKEAQELAKLRLEALMQQHTQQSERKILEHQRYQDAERLRENLERQKLEHKQHEELVRTQENEELARMKMTALLQGSTSTKAHPGSHSDEEAKKLAQEAERLEKAAIAMKREQARLKIQSCCLKYIVKQRLQKLQAEQAAAIAKLHNEEERKRLKAIQEKEMALAKLKAMMDDEARAREQEIKALEAQMLERARLEKERLAKRHAAARKIQSHVRGYLGRQRVKAIQRKIEHEREERAKVMEAQLAAAEAKMVEALSATGGSTGSNEVAGSGEAASASNPEDWVEYWDDNAQASYFYNIKTQEASWTRPFSAPAADTVSASEQDPNAYEAYSSDVSGYANGAVGAQGYADEYGFYDQYGQYHYYEEQNATYQNPAMQGMASMYPGYAAAAAAYAYHAAMAFGAPMMYGGAMGYGGQMMNPQLVNPMMMTMNTATAMGPNTNPAIPSAATPEATTDTDAPPDPWEKFFDQYTGAAYYYNNITGERYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMS5</accession>
    <name>A0A8K1FMS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMS5"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="44969" checksum="39269C366A195962" modified="2022-08-03" version="1">MGMEEAALRAKIQAMKNLLHAKQRADSSSSASHRPRAGGARSYGTAYAYSRPMGAPHHAVVPSRSWPQHRVSNAVTSANKVWVNKDAVSTTGVSPTHRKSPVATLRAHNSVVQWRPNPTLAMRAKQLQMLRLEDGEYAKANGGFSLVRSDVMTAKANAVTSTTKPRSWLAKPVKSTATQRAQATVNRARKTRLKPKAGPLRTDYCVFFNKFGYCNNKNACKFIHDSRRIALCRKFVKGECTDAACRLSHDKNKMPVCVMFLRGSCTRDDCRFLHVKVSGTAQLCEAFLQGYCKDGAACKLKHELPSSRHKRPLGTSNINEPQPRKLAKLSTTGTSNANAASDPENTAPQHQVESAPSSSPSLTSSSSNGDTAPVDTETNNATLSIRPNIRFAPRHQTAFPSLLSMWKKAGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNE2</accession>
    <name>A0A8K1FNE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNE2"/>
    <dbReference type="OrthoDB" id="124164at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="38920" checksum="30D756B7BA2C267B" modified="2022-08-03" version="1">MLSVDGVCVFRGEEERLRNGITDMRDLCQELARKTPWIYGDNVNYVFGYVAGGAYLELRILFRNHAGKTGTSVLRHYKLSRNAERLALLLALLNIARLLPAIARACPPGAHREFEDVMGSGGVLVRVNPSCVEKCFLVNGPERIEHLRRIYDVLSANNVPNVVCLVKLKSRVAVFEPRGEKTRPATLSELFIAIRQILEALVVLHAASWMHRDIRWPNVMKHRDGSGWFLIDFDDAVENPQQHQTGRLLSKEQHTPELSSGDGSHTSAVDVWSVGYLIDRSRVSWSDRLCLSDFTTWLMNEDPSRRPTAAQALEKLLHLEQSESAKRAKKEEGARKKSKLGKDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNL5</accession>
    <name>A0A8K1FNL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001682</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNL5"/>
    <dbReference type="OrthoDB" id="204376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="233"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="332"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="365"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="54998" checksum="008DEA27E5A49BB9" modified="2022-08-03" version="1">MQALWKANERGDIEAIERLLEQGVPVDAADARGRTALHSASKRGFVEVVQLLFAHGVNADVKDKHGSTPLHLASKYGQANTVRLLLARGANVNAADKLGKTALHLATEEREYVDVVKALLEHDPDANAMDKDGYSPLHSACYWGCLEIVHMLLAHGVDTNLVNKDGNVPLHLATCWGNVEVAKALLEYGIDMNVAMGAWKGRTALHLASYQGRVELVKALVAKGADLEAVDELGKTPLQLACQSRRLNVMKVLAASGANMNNLDKHGISSLHEACRHGRLEVVRKLLAYDADATAVQKDGKTALHLASYNGHVGVTLSLLTRGVDANATDKGGKTALHWASQRNHTRVVKTLLAHGVNVNAVHKGAWTALHIASHKGHTRVVKLLLAHGANVNIVDKAGKSALHFATLSGRTRVAKALLLRGAQQTPPATTRSSQNLRTSDGCTSLKPSYPNLSCAAVPENRPDTHLIASKPQSFSVSCHSKPHSAVNRLDYRQFNSQAQYLDNQVGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNU6</accession>
    <name>A0A8K1FNU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001922</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNU6"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="659" mass="72734" checksum="716B1EB92633A7BE" modified="2022-08-03" version="1">MAEVTIRQQQDEEEVHILPQLKQPHTSSEEHKTLRLTHRRSVQPQDGDDDVNALPNHVKSKRNSVPVVRPTNRTLLPTLEAIEAITKAVQDELAAIEDFEQQQGEEEDVTSSRDEATRDLADLYCERARLLVEYTKYDTSVPLTEAFLLVDDGQEQDDVAKDVSAMQQGLTDAVTAISMNVELVIGYDLAARCARALGRIKYAINLTNLGLRVEAGNADLLQLKKELEVDTDTMRFTFAPSLLYRLETESNEVSGRQQAPSDMLQITTTTSQAEDFQARYHAMEVLSGSVMLRKMEQMMHHNIHHQCAKVDEVKALEAAFNQTMGFLAALLLDSTTTSRATNIEAITLENIGKQLTKSSVLVESNCLRRWAVGQQARGMATEKQILLRIGATSNIAKITKSMKMVSAAKMRGAELRMVAGRPFAGWLDNVNATARVIEKDGFIPKEEIEGENLFLVISSDRGLCGGINSGIAKTTRKQVSTDDDKLQLFILGDKGRAQLRRDFAPQIRGSATEAYVNPPNFAVASAIAEAILASAQSDNEKVHVIFNKFVSAIAYLPTIRSLAVSPDSEAFANYELEPADSEAEVLTDLKEFELATAVYHGIIENNTSEESSRMSAMENATSNAQDLISRLTLQYNKARQARITTELIEIISGASSLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPR9</accession>
    <name>A0A8K1FPR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPR9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="132" mass="15081" checksum="FC57054215CA2080" modified="2022-08-03" version="1">MDATTKRALFQAVDDGDLDAVRAFFTLPSATEAIARSNADHRLTRETAVAEDLPPTNRQFTSRHARDCWYLYSPEESEEDQDSIFKRIIKHQQFHVLEWFFSTDACTVIGDTMCGLIYSVLSSAFTYAERMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQA5</accession>
    <name>A0A8K1FQA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein C10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0456 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQA5"/>
    <dbReference type="OrthoDB" id="75738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026317">
        <property type="entry name" value="P_C10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13463">
        <property type="entry name" value="PROTEIN C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13463:SF3">
        <property type="entry name" value="PROTEIN C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14974">
        <property type="entry name" value="P_C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="530"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="656" mass="72759" checksum="8610C5A6AB06B9C0" modified="2022-08-03" version="1">MLIASDGSAIELLDEVFATLAQPQNKQRLQTLLDQAYGDVALICQYYVPQVISLIALVVTKYGFAESLEGVKASIRVFQQLARTDDEANEPDDALGPKLIRLRKAITPTGAWIREDAAADAEDQQKIREEEAQRQRALEETQRMERLAAENAKKARLRAKKLALGLDPSVPRLPLLEDAPPRAIAAHANTRIRLRVAARFTLRYQWFFNGREVSSEDEAVEGVRTHTLVLKRLTRRVVGDYYCVCENEEGQVSTPTTHVSLVALTSSHVEMTKTFKALPSGEPMVCCGKNIIAMAVNNALVLLDRTTLSAVQTIPPLKLTDVKAVAWSSTTKVLAVATSTNTNSIVASSVTFYSLNEEDAASAVPVAFPPSPTRKLSMKSTANTAKRVLTRCLAVNRLVTLHGAVECMQFVDAGRALVLADRRNTLAFYTLAPAFTSQKVISYARQNRISHVTATRSCVAVCCREQFFVEIYDSHQLENPPRRLEFKFPVHRTAFDTLGFSLAVAEAGCMKAWISIVDPRSTSSSSTVRFVAHVGKVSALQWTSASSQLLSCGFDGYVKIWDVEILVCVFRVHFDLHGLYSGILLPPLVESESTESSLLLTLGFSQCRLHARHVQQLNAFEDTRRRQHDRLAAQIQKLWKGRQTRALIAKYIKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRD8</accession>
    <name>A0A8K1FRD8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRD8"/>
    <dbReference type="OrthoDB" id="10597280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431813" evidence="1">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="298" mass="32763" checksum="4B255AFF294F047C" modified="2022-08-03" version="1">MKIPSILSCLVAAALVAANAHAQEYNTTDIEAFSFDSLETPVLHAAAVEEETPETAEAPASFSWKLKTGSTRTISGVKKDPADSVASSHGGGSITISTDGIVTMKGSPRYYLTAPNADFLNVEMISYGRLKSKKKFKDLAGMTMVTRSNHGDFGNDPCQAMGYYSRIYFNTGEFAFQKEFFHENQKRTIYTASRRQKLFDGGFPVNKWVGMKFVLQTNPDGKSVSLKGYVDMTGGKDGGDWKLAFETTDNGGWKAMSTVPSKCGYKADEVVLRAGKNSYFRTDDVDTFEWKNLSVRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRN0</accession>
    <name>A0A8K1FRN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRN0"/>
    <dbReference type="OrthoDB" id="274726at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="73" mass="8483" checksum="CD5BFDC72629609E" modified="2022-08-03" version="1">MAADRYNINRQWEHLQAKYVGTGHADTTKFEWAVNQHRDTLASHVGHYDMLSYFAVAENEAIGRVKYNMLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FST1</accession>
    <name>A0A8K1FST1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FST1"/>
    <dbReference type="OrthoDB" id="64211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="36560" checksum="1F1D61AA293C01D4" modified="2022-08-03" version="1">MMISTSCPVDHADEKKTRSRGSTSSERGKALRVRRKEYEENLRSRVRALRHQVADLQSQRTIWHAKILFTNCSDTGSLAQLVRHYYTLFRFGLQTPKPHLNEAAIKRIRYQEHFMQQIIDPDAQVSEFVGPQASMMQWRQYTAAHASFIGDIKSVEVTGTPESPNVIIHSLFHVIISRATFAIMFPQMAQNEDVVRKFLHKRVTYDVISRIRFTKDGRIGGKDVDVDFIDGFLKAGFSMEDVSELMQLAALSSHNTIQTASDTVKEPLTSRKRARSDQKTFQSSEIQEEKEAGTKMRVAFLLGDESEEKTEASEKTTTRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Q0</accession>
    <name>A0A8K1C2Q0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Q0"/>
    <dbReference type="OrthoDB" id="168391at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="397" mass="44155" checksum="F3512C00983368A7" modified="2022-08-03" version="1">MVFDALKRPGWHTIADATGDSRGHEAQIQTEENEEMSPEASLAVQRWVIAANEGQSEGLCTRDQHGYERLYTQLVRRIRQTHASQQEDELMMLRDDDWARDRAVFEYIADAELLDAVHSVAVAWSNDRSSNSIQRFFTLQTEETATATATAPPLPCRQSSMAEKLARMRTQRSLRVSASPKMDGPPGESVSVSTESVESPAPVTRRETTDDAAHYFAIETRLALKERLQTVQKQLPVLLVQLKLAWMKCFAAENANSDATTQATELVTQGEALAKHLLDACTKAQTTGAIQEYKQLVATVEDELQALEALVTRLSSTSPSKPAPSAAIEPLTREVASSEPTQRDIKEQFLARVQLDRDELVLPSMKAYYAKVAPPYAAYLAQDKSTRQPLRSKKPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C367</accession>
    <name>A0A8K1C367_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010405</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C367"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="196"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="33913" checksum="2ECD311A7B53E597" modified="2022-08-03" version="1">MGERKVLNKYFPPDFDPSIIPRRKRPKNQQIEVRMMLPFSIQCATCGEYMYRGKKFNSRKEDVVEEDYFGIRIFRFYIKCVTCSSEITFKTDPKNGDYVAEHGCQRNFEPWREKDAEEEAALKQKEDEEKGDAMKVLENRTLDSKREMDILDALDEIKAINQRHSKIDTDALLQQHAQKSTLEQEEQKQKELEEDIRMAKEVFEQRQKRTAAEMTGETDTTQETDGPAVKKPATTVKSFEKTTEDKKPAAPALPNIVVKKKTEAGSKKAAGGKKKAAKKPVVTTLVAQYSDSSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3N9</accession>
    <name>A0A8K1C3N9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ras-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3N9"/>
    <dbReference type="OrthoDB" id="1562946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04519">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="545"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="775" mass="85999" checksum="85D4278807C4AE53" modified="2022-08-03" version="1">MQATNASTASMMPQSTASELPVRLLTTAEFDRLCLDTALEIEDSEADVVATLFDLLRLYGDLEFEDERERAFGTAMMQHVADTFVYLGSEWLSDVTTRVSVVGDDEDLRQRLSILRVEASEAFEMSVEERIRMAQNRLEDAIDHDLVVFLGDMSVWPSTHRMLRGEKATILRREIRYGIDTALRTTTTAWVSCVNASSAVVSVSETPIAPSPSAEMKPSDMLNAARGISLVDDFEDRNPCQVSILTEASGKDEEGGDGKTSGKEDLTFPDSSMVESVANATTAIVVYDEKTEVACVDRRGEIDVCANDALAAIAAVGDQFKAMVTLVIDATLTTHNVETISSQEISLRDALVASVVETFQVVVTKEFNEERTEVQSAQVAEPEPRPVVAVPAPATVSPPRTPNVTRHSRPSKSAPPVVRGARGHRINPPANTSSSMGRPKSLTKPPPAVRHTRASLARLQVNAHARTLMQIAHYANLSELPSPTVQQSKMSLRRFDSADAFPLYEQRTCTQNETASLRAFEDAVRKELAGLNGQEDLFLRSTSELSTLLRDVSQEHGRSYFRYALREVFGEHSTLYDGGVTHAQVIKYTQSVVKRLARAIHFAPLVLRVCTQLALREFQVMFPSCKHSERIVIGGVLFLRILCPALIKPEMFGFKPHTSKSLPIGVQIAKLLQLALRGTPTDGHQPEDVASNEFIASFHPYIETFFSRFPVLLESLPEEGRSQVLRYASWDETEATRLATAWHSSLDLTRLRGMSMSTHEDMKERKKKFSLRFWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3V6</accession>
    <name>A0A8K1C3V6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008608</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3V6"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000005">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="2"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="309"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="63230" checksum="E12690F047CC0588" modified="2022-08-03" version="1">MKYLAVTGGTVSGLGKGITISSIGVVLKSCGLRVASIKIDPYLNCDAGTMSPFEHGEVFVLDDGGEGDLDLGNYERFLDVTLTRDHNITTGKVYQEVLQKERRGDYLGKTVQVVPHVTDAIQDWIERVAQIPVDGSDQPADVCLIEVGGTVGDIESMIFLEALRQFQFRVGVENFCLVHVSLVPVLGSVGEQKTKPTQHAIKELRSAGLTPDVIICRATSELEPSTKSKIGMFCQVSGNHVLSVHDVSNIYHVPLLLAKQGAASILMSRLQLMNRFREPDLAQWSAMAHRVDNFTQMCRIALVGKYTGLQDSYLSVIKALKHATMKCDRDLTIEWIEASDLEPESKDKDEERYDAAWAKLRSCDGIVVPGGFGDRGVDGKVLTAKYARENKIPYLGICLGMQVAVIEYARNVLEWKDANSEEFDSQTPHKVVVFMPEINPEVMGGTMRCGARQTILHEKEDPTKRSLASYLYGKDQRIMERHRHRYEVNPEFVSTIRDAGLNFVGTDDKAVRMQIVELDRDVHPFYFASQYHPEFKSHPNNPSPPFYGLILAASGQLDGYIAECEANGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C431</accession>
    <name>A0A8K1C431_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008678</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C431"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF97">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="145" mass="16188" checksum="6CC97FAE2D86E817" modified="2022-08-03" version="1">MNGGSFRDLRISPTAARNGNGHGNGHSNGFRTGGGSPINNYSTFQSDAGVQGLMRTSDRIEQSKKTLAESEDMAKHVLVDLELQRSQLHDMKGMVTETRVMTGEAKTLLQRIADRSFRRKVCLWMIIVVLAITDIVVFYSLFIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C459</accession>
    <name>A0A8K1C459_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ODAD1 central coiled coil region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C459"/>
    <dbReference type="OrthoDB" id="6766775at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051876">
        <property type="entry name" value="ODA-DC/CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049258">
        <property type="entry name" value="ODAD1_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694:SF18">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21773">
        <property type="entry name" value="ODAD1_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ODAD1 central coiled coil region" evidence="4">
        <location>
            <begin position="143"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="523"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="347"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="612" mass="69269" checksum="B6EEC14BCB798C32" modified="2022-08-03" version="1">MLHTSSTGAMATSTGGNNADGLTQLQREYRNMELNRKVYTDESHQVMRRQQAVIEKLKKDNEDMKTELMLATRHLNESAATQQQEQLARAQDQIDGFQKKNMVELKKLETLAQQIQLMKNKVLHQKKHMGGVNAAKENQQMVQKQIRILENRLDKSLIKFNEALAQNKILREDIDNLRRERVVFDTIYRKLEKEHNDKKKQMAATIELSNLAYEQRDAAQMELRALQDANRHELDEHRRLINELMTRLEESKRHNDDKRSGSPMHPSRLHSGDLSFDDESDMKKKLQKGTWGVAKEKVHVQVSIERVQNFEEAFLKLKAATQIDDLEQLVTSFIKKEDQNFSLFNYVNEQSNEIEKLEELIAELREEEKKYSDDSGDDISQHKQLLKELEGKLHVTEQTADKCESKCQDAQKVVNAVKIGIQTLFTKIGCNSQTMVEMLGDAVVTEANLMQYLGVIEQKTNEILHQYATNVLQQPSHKGKKSDQIEQEAIFAAHATTNATSSTSMAHGTGMAAATALHSVLGMGPLTPMGQEPLQINPPNLEDYSSEDDDDGDNEDSTHPLTRDELKVRTLKGLRRLNHGGGGGGGGAPATTSKEIKRFNALSPTAASRLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C551</accession>
    <name>A0A8K1C551_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C551"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437390" description="Elicitin-like protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22394" checksum="DBB2DFC05BAF1EB6" modified="2022-08-03" version="1">MKLSTAVSLLAFASGSIAYAGECSTKQLRKYDSKLTAACGSDIQGLYASTGTTSIALCKETKCVEAIDSIADDLPDCTLGGLSLPNMFDAIVQYCKAEGNSSHSGSVAIEKPECSLSQQNKMTDMRSEPAMTKVCGPYEAMGGSKAIAKICEPDCTAYIKEKYIPALPDCSVNGAGVRVSAKIMLTYCELPPDAAGALTSAGVAALASLAVAMLAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5M6</accession>
    <name>A0A8K1C5M6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5M6"/>
    <dbReference type="OrthoDB" id="5586934at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802:SF2">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802">
        <property type="entry name" value="SI:CH211-161H7.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="31747" checksum="9220A61538333AC8" modified="2022-08-03" version="1">MSFAPLALVNAGLFTVQLYVNYAMSRSIGPMSRKHETLITPAPYAFSIWGLIYTLLTILVVVDVFYPSISLFAGSPKPGMLRLIFAASCVGNMTWIVLFSNEQIHLSTFVITLLWGTLFTLYVYMISDRNKHELSYARYFCCELGLTIYFAWTCAATLISFAVSMQQIADDYLSLTVYIILLSVLGVATISAVVFNNDVAFGLVAMWALIAVSVKSFPWERAAIERMHENIRVCAAQNAAMVAAFIAITLLVRLLARFSNNYEALDRAPPVVNGKSDTARIYYGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5N0</accession>
    <name>A0A8K1C5N0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transketolase-like pyrimidine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006527</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5N0"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="537"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="912" mass="101586" checksum="E3CEF672201E1626" modified="2022-08-03" version="1">MLRLQGAIPRALRSAATPMSTMRLTSTRSFSSAPSLEALALRSMATAFRQYGHLQAEIDPLGLHKPQSVKDLEAAQFQALLEQTTSGKAAYEHLRKAYCGKIGFEFEHLSSPEEKQWLAEAAEALDASFPVLPSDLRNAYTSMLQADVFETFMAKKFSSFKRYSGEGAEAMLPAVNTVLQAAAQAGTSDVVIGMPHRGRLAMMVSLLEYPAHKLFYKVQGHSEFPEGYEGVDDVTSHIAQSIDKRFGDKKVHVSLLHNPSHLEIINPVTTGKVRAKIDAGADAMGFMLHGDAAFSGQGCVPEGLSLSQLPSFTTNGSVHLIVNNQVGFTTTYRDGRSTRYASDIAKGIEAPVLHVNGESVAHVIQASRLAVAYRNRFKKDIVIDMIGYRRHGHNEVDEPRFTQPIMYDAVSKAGRFPFKYSQELQQTGLVTADGVQKLVERVNAHLESELQKVTDGYKPTEIDAFKGKWSDVRQPKAHDLYEQPASGVDAETLIKVGLESVKLPGHVMVHDRLQRSHIEARKKMLNTEGRSLEDVKVDWATAEAMAFGTLLQEGHSVRLAGQDCRRGTFSHRHAAFTDQGTEDLYFPFKHMESSKARFHVVNSNLSELAVMAFEYGYSWEDPRNLVLWEAQFGDFNNGAQIVIDQFLSCGESKWMRQSGLTLLLPHGYDGAGPDHSSGRVERFLQLVDTPALTPPSKKKGEEDVNDWQTYQHNTNLIVVNPTTPANYFHLLRRQQLREFRKPCVVMGPKTLLRLADATSSLAEMGPDTHFQPVYTDATITKPSKVKKIMFCSGKFYYDLVRERNKRLGSKADEVAIVRVEELAPFPFQQVVEELNTFENAKKVVWVQEEPLNQGAWLYARPHLEKVVSKKALPVEYIGRESLAACAVGLSKKNTQQTQEIFAEAFGPAPVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y6</accession>
    <name>A0A8K1C5Y6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y6"/>
    <dbReference type="OrthoDB" id="153600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436990" evidence="2">
        <location>
            <begin position="24"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="27968" checksum="68BA93335285A504" modified="2022-08-03" version="1">MPSASVIISAVFAAAAALGSVDAHGYISSPKAQFKPGPVYTTYNAIITANDNAAFKGKIFNRSPEQNTQVFTSAWPQTGYKSLRALFDKYVKDCGNSRDDIAPVDVSNLKAMTWQNNEYKEGFLGSHHGPCEVWIDDQMITHDDDCVAKYKGFPASIPVDYSKCKGNCKLSFYWLALHSQEWQAYKQCVPIKNGAGGNAGGNTGGNTGGNNGGNNGGNNGGNNGGNNGGNNGANQGGNKAPSPTKKRTNRSLRNFVDEAEGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Z4</accession>
    <name>A0A8K1C5Z4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Z4"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="363"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="531"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="614"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="715" mass="79517" checksum="018690F9F0657993" modified="2022-08-03" version="1">MTRRADEAEDVEMNAAEEEAIRAKLRESGWEKKKLRAQESKGDDDDDAKPMDVDDDKKKKMSGSGSSSTRDRGRERDDRKSGRSSRRSRSSRRRDKDRRRSDRDRGSRRRRSLSASKSRSRSPSSSRRREKDRGRSRTQKRRSRSASSSRSVSKARDTKRSRRSRSPAEKDVKMTEEKDKPEAAKEKEEHSNGAKEPEGDKKDGSSRDVKDKSDHRKSRKSSRRSRSASRSRSHRSRRRHRSKSRSRSGSRSRRRRSKSRSRSYSRSRRHRDRDRRRRSRSRSRSYSRRHRSKSKEKKPRRDANSSPEPHEHPPAPVMAANPLNSSIAQLMQQYPTMSLQDIIAKMQASNITMTASASMKPARELYVGNLPPNITGPQLQEFLGTIIQQVGLSVQPGNPILSTWISTDGHFAFCEMRSVEECNLALLLNQLPLLGQPLKFGRPKSFVGPAQPMPIVSARTQTALANLGCTPNPQWFATPSLSDIAGATGSLAATTASLLGFGSTSVPSVPAATPFVAPAAASLTGIATTSDTLLMTNIPVVLSEDQVKELVQPFGALKRFTFVADPTTGQSTGQALFEYEDTKVTDDAMQGLNGLDLGGIPIAVQRAAASTDETSVVVKMANMVSEDELRDDEEYADLKEDVEEECKRFGLVVAMEIPRPKDGEDVPGVGNIYVQFEDASQSGAALKALSGRKFGGKIVQVTYFPMTKFAQKAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6B0</accession>
    <name>A0A8K1C6B0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_003169</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6B0"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01200">
        <property type="entry name" value="WHEPGMRS_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000025">
        <property type="entry name" value="Glycine-tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="14">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="189"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="685" mass="76433" checksum="B3AEA24212F81AA4" modified="2022-08-03" version="1">MTNPPAAPVDLDALRASVTRQGALVRGLKQNGGAAEDIKAAVDELKKLKVQLDAEIAKQGPETDTLSKADKKAMDDLLIRKMFVVPSFEIYGGIGGFYDFGPPACALKANLLRAWRRHFVFEDKLLEVECTNLMPEVVLKTSGHVDRFTDLMVKCTKSGECYRADKLLEDHVENFLDKNPNLSAEEVEKHRLHATMAESYSPEEIHNVFQEYGIKAPGTGADLSFPIPFNLMFQCQIGPEGNLIGYLRPETAQGIFLNFRRLLEYNAGKLPFGCAQIGNAFRNEISPRNGLLRVREFQQAEIEYFANPKDMRHPKFNLVAALELSLLTKTNQLTDGKTVKMTCADAVAKGIISNESLAYYLARTYLFCEKIGVDLKRLRFRQHLDTEKSHYATDCWDLEIKLTSGWVECAGHADRSAYDLTVHSKKSKVEMVGTHKFDKPEKRKIVEIKPNKGKMGRSFKADLAIINELLEVLKEDTEKALAFEAELETKGEAVIGPNCDGKQFTLTREMLSIQVVEKMVSEEKYIPSVIEPSFGIGRILTAIFEHNFSTREGDDKRGVMSFAPVIAPIKVSVLPLSSNAAFDPFVGELEKIFDEDDLECKVDTSSVAIGRKYARADELGIPFNVTIDFETVETRTVTLRERDSCAQVRIPISDIGAAVRNLVKGAQTWQDVVARYPTVAAAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6B3</accession>
    <name>A0A8K1C6B3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6B3"/>
    <dbReference type="OrthoDB" id="199574at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="430"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="610" mass="67060" checksum="04B6686A72958FA2" modified="2022-08-03" version="1">MSNSNPPYANTPNGAPNAAQYAGYAQFYAQPPQPQGQHQQYPRGMMGPPRGPGPTFARPPPPGFRGPPGMRPPPMMAPRGVLMRGPPPRGPAPQPNSANQWQWSNGRTTETATNGTTVISAPPVRFNMPRGAPAARPAAPVAAFSSPPAPSAAAAGGMGGANTKWPDSLHDYVKRAFARCKGPADQSLTQNALKEAITNAITTNSLWTKNWAAEPLPTIVGDTVTPRLNVVNNAPRGPMARPPPPMQSAFRPPMTGHPAFPRGTPPGSFIPFNAPLTKGQKRKQETHFPGDGGPEDMQKKNQRRQRFLKEQAELGFTVTPSVDPKKARVLTSEGELDLEAMTIKGTCQNIEKEYLRLTSAPHPSTVRPEPVLKKALEMVKTKWRAGKCDYIYACSQLKSIRQDCTVQRIKNDFTVLVYETHARVALESGDINEFNQCQTQLHELYEKSIPGKAIEFLSYRILYSIYVSLQAKKPDSNAGQLGMYSVLSSISKRLREDKGVAHALAVREAVSMNNYHRFFQLYVDAPNMAGYLMDCMVPTIRLRALRTICKSYRPNIPIDFVRHELKLENKDGDAFIQQSGIVFVNGSDNELVDTKNSDIVWVLSDQTSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6H0</accession>
    <name>A0A8K1C6H0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003411</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6H0"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000016">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="460"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="466"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="512"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="512"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="563"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="567"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="625"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="640"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="667" mass="70585" checksum="C73A030647B1BE03" modified="2022-08-03" version="1">MGANTSPLASDAMATALAKSKKRKTSDPPPPLTVVGSTATATQRPTIDLNASSSLERMGTALDVSQSLMDRSLLDPALDKPASLTLEDCRTQIQQLTTLMSALRTSDVDTVASQLQRVFAADLTVLSTLQTAAQRAVHSIQTRRATPGGSNQPASTTVDVDVDGDMVVEGEGDDHEEAAAQALTGLRQSSNGSPSAAAAAAAAVAAVGIPEGLASPAPERPRSVSAPSTVFNPMMPMASPTSAIGGLTGMSPRHSMPMFAPHPVRPADLPPFSQSMSMFAPSRSPTHVAPAASPSALPSIFARGVLTPIATPFEQAKQQQAMPAEYATTPFATTPMVNAPLTTPNAPQQHMAPFIDWKSLATPQGQNAASLALSAPTMSPAAIVAAANALTASPSSAVPNLTPVTNLYRSTSQSSNGGASPMKRKSISTKQLVAAAVSSNPNITMPIAKSLAALERANPTRKANPRRWTKEEDDALRKAVENHKEKNWKAIAAQVPGRNHTQCLQRWTKVLAPGLVKGHWSPHEDELLRRLVAGGNKNWGEVAAKIPGRTSKQCRERWHNHLDPNIVRGAYTPEEDRIILEAQARLGNRWSVIAAMLPGRTEDAVKIRWKSHCRLWKARKYLRKTGSGQSEGSTGTNEAGADDDEDLQDDDGDVDVDADEIEVETAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6N2</accession>
    <name>A0A8K1C6N2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6N2"/>
    <dbReference type="OrthoDB" id="65257at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000274">
        <property type="entry name" value="ras-related protein RABA5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="38171" checksum="4F52576E5C0BF948" modified="2022-08-03" version="1">MTGATHKQTPAFSPLQAYMSAKDPPTRSVRYSAAGETTASGYAHDRFGRHSVATTVLSPSSMTTSPRFSVSSASGDPEYTLKIVLIGDSGVGKSNLISRFTKNKYQPKHVSTVGFEFATKTIRVGERRLKAQIWDAAGQDRFQSLTAAYYRNAVAAMVVYDITNRASFENVSKWLAQIHEHSHESLVMILVGNKCDLAHLPNSREVSTLEAARFAAKHSMEFVETSALDATNVVDSFKKIIVPVGRLLSPNTDPNSFVRLPQGWRRVLSRTRPGEYSYENQYTRERIAFAPKEAAKPSQQRFRASGSVSGPVSATVTRESLRLQHQKAFLAQTNAPQCGVCSVCSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Z8</accession>
    <name>A0A8K1C6Z8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Z8"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000188">
        <property type="entry name" value="Actin like 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000007">
        <property type="entry name" value="Actin like 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="43920" checksum="A833A28BF5286737" modified="2022-08-03" version="1">MASALLGNQPLVIDNGSGLMKAGFAGGETPQVVFPSFVGTTKHTRMMPGGAYEGGDVFVGNKVQHHRGLFTIQYAMEHGIVTDWNAMHRIWQHVYSKDMLNVNSEDHPVLLTEAPLNPVANRQRAGEVFFEAFNVPSLFVSPQAVLSLYASGRTTGVVLDIGDGVCHVVPVYESFTLPHAITRMDVAGRDVTSHLQLLLRRAGYNFQTSAEREIVREIKEKLCYVAFNPTKEEQLEAEKSAASVKDLLSAKTKAVAPPTDDSSAYYLPDGTILNIGAEKFRAPEVLFRPELIGSEGGGVHECLVQAIMKSDMDLRKTLFSQIILSGGSTMFPGFGDRLLAEVRKKAPKDIKIRISAPPTRLYSTWIGGSILASLATFKNMWITKSEYEEYGASILHRKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7C1</accession>
    <name>A0A8K1C7C1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-diphosphooligosaccharide--protein glycotransferase</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_013440</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7C1"/>
    <dbReference type="OrthoDB" id="10261066at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="18">
        <location>
            <begin position="10"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="426"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW57966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="761" mass="84212" checksum="8C9E9B6AA020D09D" modified="2022-08-03" version="1">MTPSPLVSTALLALICALSVLVRLFPVVLWGSVIHEYDPHFNYRVTKFLHAEGAYELRNWFDDRAWYPLGRSVGETVYPGLMLAAAGLHWVMETVFRLPVQVKHACVFVAPVFAALSCLSIFALTKEVTKRTTTALMAAMLLGISPAYISRSTAGSFDNEGVAIFLLVATFYAWLRAVRTGSMLSAASAAVLYFAMVISWGGYVFIINLIPLHTLAVVAMGSYSSRMYIAYSTFYPLATLMAMQVPFVGFNVILKAETAASHLVFLGLQVFALERWLRGQLSSEQLNRVFYKACAAVGGVFALGVVVAMAMGKLQWTGRSLTLLDPTYASKYIPIIASVGEHQPTAWGTFYLSLGPLMVLAPLGVYYSYQELDEGHLFMITYAAFAYYFAGVMVRLLLTLAPVACFFSATGVSGVIDKLSIMLQVSEGDDGEPEESEATPPPATPTVPPPPSTPSSGKSAKFKKTKNAEALAAARLAEAQARTEQEYQATLKYWYDLWDAFVAKTEFAPASTWAPPRSLPGGISLMLVAMVLLLIIHARQSANVARKAFSSTSMVIETWDSTTHQRTVHDDYREAYYWLRMNTEPDAKILGWWDYGYQLSSLANRTVIVDNNTWNNTHIATVGRVLGSSEVAAFPILKSLDVDYVLILFGGYAGMHGDDLDKLPWFLRISQGVFPDAAIESEFTVNGRYIHAKENATRAMTESLLYKMSYYGFFPDDEVNTTRPDLNRNEDIDARGIGFSHLEEAFTSNAWIVRIYRVKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7E5</accession>
    <name>A0A8K1C7E5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="4 13">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_013473</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4 13"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7E5"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000027">
        <property type="entry name" value="protein disulfide-isomerase A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000042">
        <property type="entry name" value="protein disulfide-isomerase A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF240">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488326" description="Protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="342"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="405"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="501" mass="55179" checksum="D3DFD82BEACA0A8F" modified="2022-08-03" version="1">MLMKRVAKALVLVMALALCVRAASWEEEEDVLVLTDDNFDEAVAAHDTLLVEFYAPWCGHCKNLAPQYAQAAQALKENDPPIRIAKVDATAHNKVAERFSIQGFPTLKFFKGDVDTVKDYDGGRTSDEIQKWVLKKSGPAVKIIESAAELDAIKEANDVVVFAVLDEAEGEARSLLEKVADAEDLAVFVASTKTDVVAEADAVKKVVLFKKFDEGKNVFDGAFEKEALASFVKANSKPLVITFSQDKAAMIFGGDIEEHVLTFVDTSKDYFATLESALKVPAKENKGKLLHVIIPTSEARIMEYFGLKEADLPSTILVNMGGGMKKFFFSAKADDYVAKIEENLGEELAAFEKSYFAGELKPTLKSAEPVDDSEEAVKVIVGKTFQERVIDSDKDVLLEFYAPWCGHCKALAPKYDELAESFADVDSILIAKIDATENEVDHPGVDVKGFPTILFFPANDKQNPITYEGSRDVEGFTEFLKKNAKKFELDGDSHGVEHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7L8</accession>
    <name>A0A8K1C7L8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ANK_REP_REGION domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7L8"/>
    <dbReference type="OrthoDB" id="97460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30787" checksum="66B4F7AD658E3AD0" modified="2022-08-03" version="1">MPHEAERVRLCFRGERSPMDEMKWLQRLKERDPTSAANVVANGQLLMELARDGQVRALHMAMEHMQEDHVLSFYAVRMFRVACYERRLDVLRFMLANGFDLEQTCMRDVLHTLVEKIAQDDEASHDTWQPVLRLLLDAGVDVNWQRPGDLYTVLHVACRSNLYAITYLLLIYGADVNAIALNDDMPLLCAERVNTAVLSPRALASHRELVSLLLDAQARRTWRRPASTSSPPASSSSLSIQSCVTSFASISLGIQLDTTELFEQSASTLFHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7Q7</accession>
    <name>A0A8K1C7Q7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7Q7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441148" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="821"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="866"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1036" mass="99466" checksum="D344F590EC428F33" modified="2022-08-03" version="1">MRRAVRLMLIGATVATNMAMVAAHGAQVHTGEASSLGNAAIARKMPCPLPMPKLNKGPSPVVSSNPPSVKKTPCPLPMPKLSKSLTDEGAGINVPGTIIMDPPPAMGGSEFAPGKVSAAEVDIAATATMDANGAVFLTGVGAPDSTDMTSTGPDLTTPSKPSKKPCPLPMPKVSKPVTEATTGLNAPGSIMMDPPLVDKASEDSISSAVDAPAMMEDEPSGGVFLGGVGAPDSADSDPMPSAPVAKKKPCPLPMPKVAKPAAGPDAGLNAAGTVMMDPAPAVDGSPDSFQESSTTTGGGDLAEGTFLSGVAAPTSDDTSPTPAPSAPTTKPSKKPCPLPMPKISSVSSKPSSTPIAGATTPTAGMDDLNLAMDGAGADLATLDTDSTLSPSLSPTSTDSSTEETEANTSGLTGAAMTSSEAMMSTLGDTSDVIDADEGSSATTTGVSDASMTTLTSPSSDSALELDDNSDLMGATEGDSTTGVSSVSTTSGSTASVSTTATDGALGMESLGADSTSDLGSVPELSDATESSTMATGTAGGSIDLEGLSATTVSSASSSATVGEPLTGGEDISPSLAGTGLPGSDGTTSMTSTSLSASTGESMGVPSTGTDAMMGLESMSDLGDATGGASLTTTAASDASNATTSSIDMAGTTLSSTLSGGLSDLSVDTTSTATLENLPGLGDALGGDLTSTTATSGDAALDMDSPATTTSATGPSASGSATTMMPGGMRAAELSSGGEALLDDMSTAGTEGTSTSSLDTFADLGGADDTSALISGAGSTSATSTSTFTATSTPIDSTLSGGVAPMDGLSSLDNAMESLSATTSASGASGPSADSASSVSALSDDGVSTSAAPSPAAKKKPCPLPMPKVSSASVSPPSASTLADLATTPVSGLGFAGALPADSAGAAFVPGAVMPAAGGATQSAQNLAGTGADGFPTAEALSGALSVLQNFLSMVSGGAGANSVATPTTSLAPFPAVTPGLTSGLAPAPVANPTSLSGVAAPIDGNSLSFSTLSDTTMMASAPSTAKTSRTLRGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C868</accession>
    <name>A0A8K1C868_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C868"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="400"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="516" mass="54121" checksum="41CDDAF421990BFF" modified="2022-08-03" version="1">MGCNQSKATPVVENAQQPVATEPLVDAAVVTKEQVAPVSETPVTEEEDKDVPPASFASVESAPVSFTDSESVPDFVESTAGVSSNTSDASTKIPESFSFSFIEVPGSQKSVAPPTSTIDPIIEEESAPSSEEGPKEVETEAPVAVEPSIPAEVEAVPAAVPETPAEADKTPVEAPVVEAAEEVPAPPASTTPVEAPVETPVEAPVETPVEAPVETPVEAPVETPVEAPVETPVEAPVETPVEAPVETPAEAPVETPVEAPVETPAEAPVETPVEPAVESVKVVAEPEAVPVEVPAAAEATPVEEVKVEAPVVEEAAPAVAETVEASVETTETPVAPSNQNETVEEAVATEVVNEVVEEAVKAAVEDTPVVEEQQKEEPSEENPADDAKEAESVTEPEVEAPHTTPVTYHITGTSVDDGVVKYLIQKTDGKTQQWPAPLEKRYSEFSDFYKNLSDSQIPEAADLPPLPSGGVGSFFRGRQNSKLIELRQEKFDAILQYVASHPSLSDSDVFKSFVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8W0</accession>
    <name>A0A8K1C8W0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8W0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="28039" checksum="C5B262D1537BBBCA" modified="2022-08-03" version="1">MTAHALPPFAHISPTKPLSSVPAMSIAKRTLGKRAPMKRKLPKMNASERARHYRRRVEGYMHGLAETHKDLRREVDTLRLLQDLQRQLRQSANVCANGSRRRMLTRVWDFIMKKEYGLGQHLSQECLTVPSTSIHYADGAPIIHLGLEITGAFTHAFIEKELYVHIPGNTRLLAQLLDCKVTFTSTVTLFFSSDGMLRFQAVETDVITGLMTSLPCPLPQAQQLAKGLQVRAVAAPSNHGVLPFALSTSSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C938</accession>
    <name>A0A8K1C938_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C938"/>
    <dbReference type="OrthoDB" id="67124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855:SF1">
        <property type="entry name" value="CLAVAMINATE SYNTHASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855">
        <property type="entry name" value="DIOX_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460548" evidence="1">
        <location>
            <begin position="28"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="446" mass="47611" checksum="D4AD99139A5B0C07" modified="2022-08-03" version="1">MVFASWKSCTALVASAVALLAAPSAAADSFAVPSFDFASIVTGEPATLGSLVDKLQTDGIISIRNIPQFKELRAEYLEAATKCASSEAAKNSPGLLYKTLPDGTERWTISTKTQFANPQLAQTQLESVCPQYLPVLREFSELVNVAASEFARALDTAAPSVDGSASLEEVVRSAENLDHFHSYSSPSAAPTATKDHVSLELHSDNGLMIFMTAPEFYALRDAPVKVPREAIVAGPDASAGLLIKAQGKPELVQPVLKDDELVVMIGEGFKSWISAGHAFKPVLHAMQMPSFSTELGKVSRSWFGKMVLLPKDRVMKNTGMTFGSYTTKVTEYVLGAKDASTFGTVACPPSMALFESDSSCTLQLFEPKEGSSATTKECMSWCNNPHVAETCTDNCNYVGELPGGGIDCWMLCLPTDVCEPGQEAQCDPSGAQASVCVNTTLPATRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9K0</accession>
    <name>A0A8K1C9K0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9K0"/>
    <dbReference type="OrthoDB" id="128271at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="269"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="360" mass="40197" checksum="65B2EAE5857B1F03" modified="2022-08-03" version="1">MALSSVVLGTATIFLRPLRYLFDIGTAVTILSEHDASSDAKTPVTPLGSVHVHVSIAHNACRIRQGADHEHVEAKSDEPTELRHLLGQFVCVRVRMQPPKDSVLATRDLRVQYQLSPATESFVFPVDHTNAFHVLVTDELLAHIDSTALVFQFIPLAALQGTEHDAKTTTQPPIVETKEAIPVPMYPMRTEETEAALRATSNAATAAETAASAAKEAAMAANAAMEAAKATTEREVERVRVHTREQQDETEKRRALELSALAKDHEMASLRYAQELQQLSDAKQQLETDRERLEAALLESKETLDKWKEQTTQTDHALELLQQRMAGDARERDELQKRLRVLEEEKLELLKKHSRVCVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9S1</accession>
    <name>A0A8K1C9S1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006923</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9S1"/>
    <dbReference type="OrthoDB" id="119241at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="240"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="633" mass="72245" checksum="1893EEF776F578F5" modified="2022-08-03" version="1">MIIYRTSIAPNKLKLATRTFRIIVALRLGHIYLNIRKRFQRHEKEYEKGFLAWLWYSRYTHLLAIGKLLWLVFAIVHYLACLRHGLIDNHTTSASATDIHESSFWSQYFLDMFNAICLLQGQGERSQTESIVANLFSILTVLLGSVLLAIVFGNVAVLVANFNANNTNYQRKLEAVVATMDKLQLPGPLCRRIHEYYTHLWSHYESLDGDISGFSRELSHTLALEVGLCRYMNLIVDVPFWKDCSPDFVMQIVLQLDVRVYLPDDFVFRQGEVGNELFMINHGTCDVYHGENTLNYRPDESSRIHSTATNDAVMPAKSCVRMQTGAVLGEMSLLMNYRRTANVLAVTHVEMCILQRETFQQLIIRYPEDRRVVLHRNLQWSIERNDKPFPWQELCEIMNVDPDPLTPAETASALLQHIECDAIDPSIQYGFQNHTTTRARYHPPPQQPQDGYGPADESIRGQVKELQRGQSAVILMIQELAANVRSLENQLTQGQGDGTRTDSVAANVFSILTVLLGSVLLAIVFGNVANFNANNTNYQRKLEAVVATMDKLHLPEPLRRRIHQYYSHLWGEYESLDGDISGFSKELSHTLALEVGFCRYMNLIVDVLFWKDCSPDFVTQIVLNLNVRVPSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB31</accession>
    <name>A0A8K1CB31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007302</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB31"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048279">
        <property type="entry name" value="MdtK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="56956" checksum="E17B28DD024FC8C0" modified="2022-08-03" version="1">MVATPSHETSALLQHADSIEIDLDDLPIITRTNSFSLTSPSYALSQSDLKVVLDYEDEPEPDWRVELSKQLKLMYPIMLTYLLEYAPGLVCIMLVGHLDSPDTKLYVDAATMSTMFTNISALSIGFGLSSALDTLCSQAYGAGRRKKIGIYLQSAFIVVGSCLLPIFLLNWHSGTFLRLAGQDPDVARYAGEFSQITVFGTPFLFVYEMCRKLLQAQNIVRPLVVIMIMGNCVNLISGYYLTYHTSMGFHGAALSRTLGYMTLAVGLVPYFWYTKSYEAWWPGWDLKAAWQHVRIFLHLGIPGMLMMTMEWWAYEILAILAGWLPNGVVEVSAHAVLMTVASSMYMIFLGMAVSGNILVGNALGANQPKKARLISRLTMTMVVSMSTLVALGVYIFRHDIPSWLINDQEAIQRASETLLVMVPYEIVDATNCVIQGIYRGTGRQHMAAKTNAIAFYVVGIPLGALLAFQFDVQVEGLWIGFGSGICTALSICAYVLYHASWQQMADEARARTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBD5</accession>
    <name>A0A8K1CBD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBD5"/>
    <dbReference type="OrthoDB" id="67847at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480976" description="Thaumatin-like protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="37149" checksum="C0638443AFD7C12C" modified="2022-08-03" version="1">MKVFTSTTALALAAVASTVSASSKITFKNTCTKQVDLYDNHSLIPLAPGATSERTLNDGYMGIFRDGTSPQATLAEFTLAGGKTWFDISIIPTGNGIGPEYCPSLDECKRFTGGVGYNTAMQIAPLSGINGAHCRVLTCLNDGCDDAYQFPKDDTKTHNCPDGTEFIITFCPGGAGGATPAPTTQPPTTAPPTTQPPTTAPPTTVPPTSLPPKSSVPPSAAPNSTAPVYKLRSINGGSASAEGETTTETETEKDAEAGVLENDVVSIETPAPVGTVAAPEETPTTGDESTTVGGQTGVTETNTQSSGGSASPVGTVMAVLLAVAAVAGVAVIVVMRRKKAELDAMDDKSPVTTMRNQCNTVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC46</accession>
    <name>A0A8K1CC46_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC46"/>
    <dbReference type="OrthoDB" id="122216at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="23452" checksum="A8482812B319DE54" modified="2022-08-03" version="1">MGSYLSIVNDTQDRWQCKLGPDEAALKIAGIIVSIVGTIATIIGTAGTAAPLAASLGANGVVAVFGVSTSALATITAGAAAASTVASVAGGVSGFSMGVAKGITDQLNKDTFHTIEPGQSNRWGKMSLSLWQQGTCVKTTIVDEKTVRTETLYMRPIFSGASDNSNNDHKIQFWLSKWGTEKQDIVSQDKARRYLTEEGQDANEDELIYFFANGTNTYDGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC77</accession>
    <name>A0A8K1CC77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the lid subcomplex of the 19S proteasome regulatory particle complex (also named PA700 complex). The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC77"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000016">
        <property type="entry name" value="26S proteasome regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="236"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00062507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49491" checksum="752A9208AB924877" modified="2022-08-03" version="1">MTDVEMTESEAVHPLQTQLEDVEDVIAALNERASPDAAIAALQAILAYEGVDATSESVQRTKEHAIYKLSQLYIQYGREKELATLLQALRPFFLTIPKAKTGKIVRTVIDMVAKVKVLNLEKALQLQADLCLDSIEWCKQEKHTFLRQRVEARLAAIYFQQQKYQPALDLITNLVREIKKLDDKQLLVEIHLVESKLHHALRNVPKAKAALTAARSISNTIYVVPKTQAQIDQMSGVLHAEEHDYKTAYSYFFEAFEALASLDEKEALGCLKYMLLSKVASGGASEVNTIINGKQAIKFIGVDLEALQAVAKAHEQRSLELFEAATKTYAAQLVEDALIKSHLGKLYKQLLESNLIKIIQPFSCVEIAHVAKLINLPLAQIELKLSQMILDHKFHGILDQGKGQLIVYDSPLEDQTYTSGLGVIQNVGNIVDSLFRRAEKLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDJ8</accession>
    <name>A0A8K1CDJ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDJ8"/>
    <dbReference type="OrthoDB" id="10676177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="283" mass="30408" checksum="4C0DEB5CF8C1E275" modified="2022-08-03" version="1">MQGLVSASLVTFVVVAGIAAVGWLRYRANPVDNGKKNDDERVDNDVQIVVDESQNQVKPLLCSVATSPFRQPFVTALRDRLETRVPRKFSSSSESDTTEVDTKHGGEESRAMKMSVAGYHAVKAKANNLSSFVRQCVSNIERTQSAPIDPPVVRPISLQNSQSPSNQSDSEPEIAVPEEHMTSLVAATDCEPTKAENPAEDAVEPAKGPVSKLPRPGNFAKRPSIPSAGPLASVPTPTIPVPSEDSVPQASEKAPLAPRKSNLGRLQQFQQLVPSNQARVTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDM5</accession>
    <name>A0A8K1CDM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000998</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDM5"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438678" description="J domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="191" mass="21903" checksum="665AFD257621395C" modified="2022-08-03" version="1">MGFSCKRAALTLFCLCLFVASGVAQDLYELLGVSSSATPAQLKKVYRKLSLKYHPDKQTSETKDEMKEHFVKITNAYRVLSDPERREKYDLYGIADEQGFKNFDEAFRFAHDGVDDSWANWLGLVAVLALGVIPIIVMQRNRTKPLKKRREALRSLSRNRLTAKSAKTFKEDFSKTRRQYVNDPTLSSHMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDS5</accession>
    <name>A0A8K1CDS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C1q domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDS5"/>
    <dbReference type="OrthoDB" id="100955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008983">
        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="TNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="34408" checksum="C05304EAA03BBB77" modified="2022-08-03" version="1">MASTLDMQSTGSSGRPGESSKEGVVKFPRRAETYRFRVSSREERLQFWLEDCASKQQWESSKLSMEDFTTPETMIPQAGFADYVSCFQNCIDTKELNESAEFYRELVPHESDDWELRLTLKIKIFVSVWTLKYAFILKQISLEPIDVLTAKVRDQADYIKALEKQIKELKVVVDKPLPPPPSPMYAQAKTTTQHHGGQTLVWARETPESVGRAFAFMGNGGIRIKAPGVYTIHLVIQHNSGVNGVTVEVQVNEKIAASTIDSNPHGHISAAPLQRVLSLTDGDEVKVVYRGNNSANSDSSLLIYQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEY2</accession>
    <name>A0A8K1CEY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000999</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEY2"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428802" description="Amidase domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="167"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="619" mass="66652" checksum="3CD191F318D4860A" modified="2022-08-03" version="1">MLRASVLVAAISAILTGLLLLGEDARLPEYSVLKQQHAVMAEGGYDLQVMDSPRLTGAPLKFFAFVLRTPVLGRIVSKVLHAENQMLEIRRVASSIPDMPLYYPYFDPPKTTANSEAPIDLAAFSSKNVNAKTSNTKGFKHWSISDYTSRYASGALSPVQVAKAFLAAVRESEQGEQPLRVFVETFDEEIMEAARASAARYAEGKPLGVLDGVPVAVKDELEIKGHQTSFGTGFIGELNGKADKDSVPIARLRAAGAIIVGRTNMHEIGVGVTGYNMAHGIARNPYNPLHHSGGSSSGSAVAVSSGLVPLAVGLDGGGSIRIPAALCGVVGLKPTFLRVPPLADDCPSVTNIGPIAGNVRDAAIGYAVMSGGDESFPPSLSQPAVDLHSFDQSNSLKGLKIGYYSSYTNHSSPEVAKAVQDSLKKLESLGAELVETKLDHLLAIHLSHSITITSEMAQNLDKYYSRFEQTSPEVQILIGFARQYSALDFLSAQRVRAYAVRQLQEKVYSKVDVFVTPSSAITAPKIPLDASATGELELTRVSHIMRFSVYGNFAGTPGIAVPIGYDEQGLPISLQVQSNHWQEDVMLRFARAAEMLYEDKQRQPQVYYSLLDEAAKQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFQ3</accession>
    <name>A0A8K1CFQ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="3 13">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009687</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Adenine glycosylase active on G-A mispairs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="3 13"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFQ3"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035485">
        <property type="term" value="F:adenine/guanine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032357">
        <property type="term" value="F:oxidized purine DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="NUDIX_DNA_Glycosylase_C-MutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000002">
        <property type="entry name" value="Adenine DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944:SF1">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="15">
        <location>
            <begin position="137"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="545"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="594" mass="66615" checksum="119DE5883F9589C0" modified="2022-08-03" version="1">MAVEPEMEDAVTTLVEGDAKCKGAHPIALRPHSEAVHQADLKRVRDVREKLLEWYTEHRRKLPWRGDPPPYPTTATHTKQTGKRKAGAMDAFCVRAAPSDDSTLVDEKKPIVDNDDDGLPSAPRRVAPYETWVSEIMLQQTRVDTVVEYFLRWIDKFPTVQALAEASEEEVNALWAGLGYYRRARMLHAGAKYVMENFNGELPSSTEQLLTIPGIGPYTAGAISSIAFQNQEPLVDGNVIRVAARLRAVGADPKNKQLINFSWKVARELVEDCDRPGDLNQALMELGATMCTVQNPQCATCPVRSSCLAYEESQQRREKPGLIEYETETDAKPCELCDFSRYDEWQGQANSFEMTRYPLKAKKNDSKNEVICVSVISHRHTEDDEPAAKAKRDNPEHDWKFLMTKRPDGGLLAGQWEFVHSKVEDGDKIPAFTQRKTHMKSRLTDLFGDAAVFTAPTSNAKAKTHTLEHRQDLGELVHIFSHVKHHMGIEHLHFSEKPPLVVAIEHDIADVRWMTLTEMNQLGITTGVKKILQLVFKAAKTPAISTTSKTPKATRSSAKATTKSETQPTPRVSRKAAVEAPSKRVKTISSFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFU6</accession>
    <name>A0A8K1CFU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFU6"/>
    <dbReference type="OrthoDB" id="6480556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17571" checksum="751330988633B073" modified="2022-08-03" version="1">MEQAQQLIYLEAALRETLRLYPSVPCMIKNATRDVVFGDGTFIEKGTRVGLPVYAMGRMTYLWGPDAEDFKPERWIDTETGKLIHVSPYKFVSFNAGPRTCLGVKLALLEMKIVASSVLSRFNIEVLKPEEVKYDVSLTLPIHGELRTKVHVARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGZ8</accession>
    <name>A0A8K1CGZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dephospho-CoA kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGZ8"/>
    <dbReference type="OrthoDB" id="247245at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000991">
        <property type="entry name" value="Dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30360" checksum="CF47B4BBD3D1F2F6" modified="2022-08-03" version="1">MLLFLALPIAGLLVGVPSGFFKEKFDVSSWKRWLILLSPFAVTPVLPLTGALIAAGSLVVGQQLGASLVAVGLTGGIATGKSSVSQLFVKKGAEIVDADVIAREVVLPGRGAYNAIVKNFGTGVLHEKDKTLNRAKLGAIIFADPAKRKVLNACTHKFIMWEMFKQLVYQRLIRRKRLVVFDAPLLFETNLLEHFCYPTIVVACSEKNELVRLMKRDNLSLEDAQKRIQAQMKLHDKVQKADLVIQNDGSLEDLLSYAEKALERAATRVGAVKELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH06</accession>
    <name>A0A8K1CH06_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH06"/>
    <dbReference type="OrthoDB" id="78280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="609" mass="67324" checksum="F55EAA045FDE8090" modified="2022-08-03" version="1">MPVGMTLQQLYSQPTFSDAHAGPVSATASTSASPAMTTTATSNAGKRSASPGVDPTRPQMSNSRSPRSSDAGHHMQMQQRGYPEQQQHITVQHYPQYGQLPPPRGFAQYHPVKAANGSEEYALADPLPFEYMRKYQEGVKDQGDHRYPPNQMQYGAENYGPPSPHPSVYESQHAHPPKNVEGQSRAAAYHQGGYPHARPPYHPPAGMPGHYAHGGMQQAHLYGPPPGSMMNMPPHHAYPPMDNQALKKEGAYNGHGVEYNAPPPAPVVPQGASQEAVIKVRTTLKTKYWRNGRRNLQCFPACKVFGDYSSIKIEDLKQHDFMWGKCRGSIFTDVTLNSSVSFDDILILGRVHSLENIPVAFEEAVIRECMLGRMVEPDVMDTMKDQWITGERLPDQPESNTARYEFKPKVWKYNEDMAQGKCKRRNVKYYVQFEAFVLVMSGDRRYYACIGSGMSTSFEVGSSRVLARQKRKAAATGTELAPQEVKVGQAPVATSSEMSMQAMHHTMMPAHSMMPPHGMPPQMYPPSYPGYGAQRALPPPYPQMHHPDANQAGMPPSHHYHYPPVPSSQSAPAPSSSSQGVKRKLGSDSSPRESSERSAKSQKTTVVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHB0</accession>
    <name>A0A8K1CHB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005404</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHB0"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000085">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="58611" checksum="7DB999F4501C25DE" modified="2022-08-03" version="1">MMQAPVMVLNTNTRRETGRTAQLGNIEAAKAVSDIVRTTLGPRSMLKMLLDPMGGIVMTNDGNAILREVDVSHPAAKSMIELSRAQDEEVGDGTTSVIILAGELLVVAEPFLSHQVHPTVIIRGFHRALEASLDIAKKMARVIDIQNREDMRNLIQSSVGTKFSPRIGNLVSDLALEAVLTVVRTSPSGKKEVDVKRYAKVEKIPGGELEDCRVLKGVMFNKDVTHSKMRRRIENPRVLLLDCPLEYKKGESQTNVELTNDQDWNTLLRMEEEYIENLCAQVVAMKPDIVITEKGVSDLAQHYFVKANITAFRRLRKTDNNRVARATGATIVSRADEIQESDIGTNCGLFEVRKIGDEYFAFFEECKDPGACSILLRGGSKDVLNEIERNLQDAMQVARNVVFEPLLLPGGGATEMRIAHELKKRAEEIEGVEQFPFRAVGEALEVIPRTLLQNCGADVVRVMTALRAKQAESEESHGVDGVTGKVTKSTDLAVWEPFQVKTQSIKTAVEAACMLLRIDDIVSGLAKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHI8</accession>
    <name>A0A8K1CHI8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHI8"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000138">
        <property type="entry name" value="Flavin-containing monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="51176" checksum="EAA2A3ABBBEE198A" modified="2022-08-03" version="1">MQHSVRTVRVGIIGGGAAGVIAAKCLRDGGHSVVVFEKSGHVGGVWRYDEATHTDASMYKSLRTNLPTAVMQLDGFPFPSGLRSFPSHTDVLAYIQDYARHYHVNEVVRLDSNVTAVHKLSSGQSSTSSPSWSISVTSSNGKEYSEQVDKVLVCNGHFAVPFYSSIPGAEHFKGEILHSHDYRTHDSFLDKRVLLVGKGPSGQDISLELANAGAKEVIVSYKSEGNDAQSKSDRRVLKPQISHFAQSGRVVFEDGSSLDAPDVLMYCTGYLYSVKDFAPSSMLYPELQVPDQPAWAAELEAATRDGHAIAPLYKDLFAIEEPDVAFIGVLFKNLPFVCFELQAKWASMVFSGQTVLPSKQQMYDEFFEQIQSTTRPLRKLHQLGERQESYFMELAKLSGTTYTPHRQVMFEDAGSLRATHPLYYREAEYTFDGDRGHWKRRLQIPLENGESQDLVRVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIT5</accession>
    <name>A0A8K1CIT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_005570</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIT5"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000104">
        <property type="entry name" value="E1-E2 ATPase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000088">
        <property type="entry name" value="Potassium/sodium efflux P-type ATPase, fungal-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000160">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="852"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="881"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="923"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1030"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1069"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1102"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="107"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1175"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1178"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1190"/>
            <end position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW62952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1211" mass="132619" checksum="C335E786F48F9CB0" modified="2022-08-03" version="1">MATARPTITTQGSSGRWIDDTRTPTTSTPGQTRPMGASFSYTGSNTPKIPLRPLRSSRNDECAPTLEIQEREHRSRFLTESEKLLLKNPSKTRESYREIESNTTEAGWHDHTIDQVLQQLQVDPERGLSSEDVRKRIARHGANTLETDKRAPVLVIFLMQFLNLIIGLLMAAALASIALQEYVEGIAIIAIVTLNAVIATIQENRAGNALDALAKMSSPQCIVQRNSRQQQITSDQLVPGDIVILTTGDVVPADIRLLASADFKVNEMILTGESEDVHKKYDADVSTSKKLTADNMVFASTAVSCGNATGIVVETGMGTRVGSIAALLKEDRRSKGANCLAQYKTKMTPLQEALHRLGVFMGLAVLTICAVVFAVGMIRGNHDPKNGDRPVWLTMVMVSVSLAVSAVPEGLPMVVTICLSTGTSEMVKKNVLVRKLAAVESLGASSVICTDKTGTLTEGKMTAIKAWGDNQEYFITGTGFDPNGNVLLDGVVQTAENNVQIHTTLLSAALCCNTMLQKEPSEDGTGSFVWTPFGNASEAPLVVAAAKLGLWSDKVGEIYPRIDEIPFTSSRKMMITVTDVPSDGKLGGLVLPIDSKVVAHVKGAPNYILPNCTRFVRTNGEIVEMTAEDRDGILEAVDELSSQALRVLTIAIHPMARNPFSGDEDVEVRFNHLKAPLIFLGLVASIDPPRHGVKEAIRTARMASIRTVMITGDYLKTAIAIAKSIDLLPVGADVDEEAVDCTILRPRGGEYLTEHDIDEITSRTAVFARAKPEDKIEIVKSLQRQGHVAAMTGDGVNDAPALKEADIGVAMGISGTEVAKGASDMILTDDNFCSIVAAVEKGRTIYTNIQKFVCFLLSTNFGEISIIFVAIAVGMPNPLEPLQILVLNIFADGMAAVALSLEKGDSMAMKERPRPKTQPIIHGRLWILVMTNAFLIGTGALIVFAVGLYWNFKNVLLDDILNGAKTVEDYKHVRCFRWQGVRAKWKMYSNCEAVYRDGSPVFPFYTPNMHEFDDDYVHCKGGDYECLTEGVARAQTMVFIYITTMEMFRAYTARSFTNHVFVGFFSNKYMQYAALGSITLTLVVTNTPYVMDELFGFAHIYWFQWVFSMLFAFIGASLGELLKCTYRRSDRLNTRWQHMSDGFDAVLLEIRNLRHHVEHLEDKLEVTTHRPARRLTLLDTSTTPGSQRETSGLLSTSSSASGQLSARLSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJN8</accession>
    <name>A0A8K1CJN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">THO complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJN8"/>
    <dbReference type="OrthoDB" id="205166at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008501">
        <property type="entry name" value="THOC7/Mft1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05615">
        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25967" checksum="07BFA6DC7969E6FB" modified="2022-08-03" version="1">MADEELIIRRRLLTRTSVVGKAGLKKCAEGVLSLFDALAEDGIDELTCKQEVDALLWEMEQLEFEANKTDILGYTCERELEAYETLNADIDASILKVSEEIEELMAKVQVEKTIRAYKEEYESISRVINELPSRQDLAAELAVEEKRLSEAQIALSAVDEKLDLRTKQFSLLMSTIQNLKSTLDEDTAMDDEEDEQQKRSGDAEDEDMEDTSEKRGATQDDDDMNGGRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK34</accession>
    <name>A0A8K1CK34_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Folate-Biopterin Transporter (FBT) Family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014283</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK34"/>
    <dbReference type="OrthoDB" id="97868at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="59836" checksum="440424CFCA3C33AB" modified="2022-08-03" version="1">MPTERDSLLPRDLEASSGALRAGAPLRLGSLASLGLLAQFAAVGFLNGVLPNVIYPVLQGYLNAEGTTIVSATLLVQLPWSFKVFFGILSDSLPIQGFRRRPYMVLGWLFCIMMLVYMAFLDVPAPYYGDASMHFTSPDAWTDVQRKTINTHAPDAATQYVIPMMLAACGFLVVETTADAIVVEYAQREPLDSRGQLQAAIHCMRMTFNALGGLTVALAFNGVQYGGDFTFAISLPQLMSALVFVYVPLLPLTWLGVRETRVHSTERRTFSKYIESFWLTLQQRAVYQIAAYKFFSGVLNNLNIVSSSNIKFYWVHATPFNSSMMTIVGTLVYAATLALTGVYGRHWNWHVSITLTVVIGILLDGLMTMVTTWDIVRNQWLWLGVPVVGYIPEGVRFLVANYVVVELISEGHEGALYGLLTTTANLASPFGRTTSKLINAQFQVWRDDIIRDTYEVRRDVTITIWICYSCKLLSLLMLPLLPSQKDTAQRLKQHGGTSRLFGIVTVVYLSVALVWSVGVNLLSLFPSTRCWPIAGGCKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKH6</accession>
    <name>A0A8K1CKH6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKH6"/>
    <dbReference type="OrthoDB" id="167989at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="265" mass="28429" checksum="A983516395A8516F" modified="2022-08-03" version="1">MTTPLTALNAPDATSDAAPLLNDGLLTSASNAGASRWPTRTRALSAARVMCSSSTGGGASWIVKGLLVCVGMVLMGAVGSFTLHQMMSPQIESLLRQRNELQRDMYELQNQVDNMTRIAESRLETIHLLEKELERQAVAAAAAADAADLNRVNGTDGHRVRMGVSRNGGFWPIIVYAWVIGGCVLLAVAYRVSGIARIETQQLRRKTGTDSRLASLQRAESITMEDKDSEDDEETGLMSGGGVTSSSLFKRPAGSVSPPDRLMHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKR0</accession>
    <name>A0A8K1CKR0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin-D1-binding protein 1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKR0"/>
    <dbReference type="OrthoDB" id="514292at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="340" mass="37202" checksum="FE2465F49ECB2B7D" modified="2022-08-03" version="1">MAELLTEFNATVATYVSELEQLHAKNTEERVFQPTFWLQHEDFTLARDVFIAASGSIGHEVTKFSLVYGKTPSQEEASSICKAMQKPCEQLVAATRVALFCGAGPSLAEEIILGALRVMKSVRDLGLVIASSDRARVPEITGRVWESCKAVTSTPKSNCIASKRSMLQCVSVLNDTIKELKEFLSEQESTSAEALDTVEDEDDFAFDSHLSDDERALFESGLRLLEMVVAVLKRGVLTLKNLTIEDSQQETITWTAKLDRGYKAVQEAVVDMGAALYPPVDVEELVSNVAAAERVGMAVLDDLQAQPELKETEAQALSHGRAAFEKQVNAVKTQIEAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKR6</accession>
    <name>A0A8K1CKR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nitrogen permease regulator 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKR6"/>
    <dbReference type="OrthoDB" id="338854at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="47395" checksum="2F6E88CD2B6743A2" modified="2022-08-03" version="1">MSMLKGVFYSEFDNIAGPQIVFQAPSDVLSSDVFDSVSSYIIIDKALCGKIITVCAQNIKIVGYPVCIEDDKYHRNALLFNIAFVFDQGVDTASYRPILRKLGALVESMERESGFLSRGESKALLEHILPQILRDLSFSGECTIPVDAANIINLKLFPTLQDPSTVFDYQVPVAIRDLRQLLDNSEWDLALQQIVPFIDGVKYVKRISVEADVEIAIVKKCLRQLLYYGCITMIDIFLHSNIYAITPKISVLANDLKLQAECALYVTKSGKAPPSFAKIFALYCSMQPSLRMSDFCVVYAESLANIDVRRFITFGLIHSFLRRVHRYPIMIDRAVPQPQPTTRAYGLPSAASPPTVAMNAPPTSNGQNKRISSSSKKTSQFEKDAMKMMNGEHNTDEICTNLMARYADLEGMVAKNPNCFVVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKY0</accession>
    <name>A0A8K1CKY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Folate-Biopterin Transporter (FBT) Family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014284</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKY0"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61133" checksum="F984B639C6CAFF1D" modified="2022-08-03" version="1">MSSRPSIPSLQDKYTIVKTPGGDELENGALRVGEPPRLLSRASIGLLAQYAGVGLVGGILPGVIYPILQGYLNAEGTIVVSATVLVQLPWSYKVFFGILSDCAPIGGYRRRPYMILGWLVCCVLLFIMAGLHVPAPYYGDASLRSVSPDKWSDAQKATINTNAPDAAGKYVVPMMLASFGYLMAEVAADAMVVEYAQREPFETRGRIQTAVYTVKTAFNALGAVVVAFAFNSVEYGGEFDFALSFPQLMLVLGCVCGPLIPLTWFFLDENRVLERPRVREYLRAFWQTLQQRAVYQIVAYKFFSGVFNSFNIVSSSNIKLYWVHATPFNNSVMAIVGQLFYASTLAITGRYGLHWNWRTIIVLTMCSAVAIDAFMTMLTVWGVVRNQWFWLGVPVLEYLPDGIRFMVATYCVVELADEGFEGALYGLLTATTNLSTPFGRSMAKIINAQFRVWLDDIISDTYEVRRDVTITIWICYGMKLLSLCFLPLLPPQKDATRALKRHGGSSRVLGILTLVYMTFALVWSTLINLLSMYDSTKCWKITGGCAPKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKZ7</accession>
    <name>A0A8K1CKZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 10">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 10">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012819</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 10"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKZ7"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1050.10:FF:000001">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36704" checksum="C3ECAFCCDF9FC3FD" modified="2022-08-03" version="1">MLAASLRLGRRVAATPLMATRAMSSVLTPDKSLERLFENNKKWRDGKKLLDPDYFDKTSKGQHPQYLWIGCSDSRVPAEEITGLAPGEMFVHRNVANMVVSNDVSALSVIQYAVEHLKVKDIIVCGHYGCGGVRAAMANQHLGLLDNWLRNIRDVCRIHHDELIKIPDSEDRLNRMIELNTVEQCINIFKIGLVQRHQAKYGFPRIHGLVYNLQDGELKELSVDYQTYVKKYNSIYKLHSFDSPDPDAYRREHLQAKMIQTLTKDHEEENGRVSVSYLKRAMRNEPLLFSETEISRALDAAQAGDSDKSTVSIEKLVAYFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLW7</accession>
    <name>A0A8K1CLW7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLW7"/>
    <dbReference type="OrthoDB" id="159613at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="16933" checksum="1A9ACDBED951628E" modified="2022-08-03" version="1">MDLPKMMRRMQSFNDGAPGSNNQRVSFSPGLTVDTSVEKTSFRKLDSFDQAMEPQWGAGDETPTPTPTPTPTPTPTPQPTPTSTRSEDSDRYVRRRRSNSECLLMMKNGQDLPGPCKEYISSVKQILARSEEKEPLRRRSMSLRNSPVLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMA5</accession>
    <name>A0A8K1CMA5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMA5"/>
    <dbReference type="OrthoDB" id="6362633at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="193" mass="20554" checksum="09375445F4FED65A" modified="2022-08-03" version="1">MNSNLHIDSNLNDLDMASYGVNAMSMASPGDHHSSFVQQLHDVQAYPADGNMMPDMMGNYDPMGTDANGKNRNRGNYRCSKCGEPKKGHVCPLVPANFKCARCGLTKKACVCEAPSTRSIGIQVEMDEDMTTRALDLSVQGIIEFQTPAGGYPSPSGYVSPSGFPSPVSYTSPPSSAYASPVSYATPPRSAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN89</accession>
    <name>A0A8K1CN89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003979</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN89"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04886">
        <property type="entry name" value="ACT_ThrD-II-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000007">
        <property type="entry name" value="L-threonine dehydratase catabolic TdcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044561">
        <property type="entry name" value="ACT_ThrD-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005789">
        <property type="entry name" value="Thr_deHydtase_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01127">
        <property type="entry name" value="ilvA_1Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF19">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="51"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="47947" checksum="307A171D6B980E0D" modified="2022-08-03" version="1">MKMRGTALKRVGRGPHEINARLFASRADDSGEVEDEIPVTFEDISTASFRIRDGIEHTSCKYSPLLSRRMGYELYLKKDYRQMTGSFKERGARNALLRLSPEERKNGVVAASAGNHALALAYHGKLLGIPVTCVMPNIAPLTKITSCQDLGARVILHGSHILEAREKADEYARNESLVYVNGFDHPDIIAGAGTMAIEILNQVPNVDAIIVPVGGAGLIAGISLAVKTLAPNVQVIGVEPALCPSFTGALAAGKPVHVPTVPTLADGLAVPCVGSNAFTIAKDRVDKTVTVSERAIALSVLRLVEQEKVVVEGGGACSLAALIDDKLPELRGKRIVLPLCGGNIDIPVLGRVIERGLAADGRLVRFVATVSDRPGGIAQLTTLLWECGASVKDIYHERAWVHTSVSQVAVKCVVETQSYEHALDLKRRLEEAGYPLQWASAADPLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPM8</accession>
    <name>A0A8K1CPM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">D-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_004092</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPM8"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="12">
        <location>
            <begin position="259"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW66327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="396" mass="43151" checksum="7A704AAAE4EBCF4F" modified="2022-08-03" version="1">MSLWMTTPSVVVDAQRVRRNVDNMQSIAQTHGVNLRPHVKTHKTLEIASMQLEAGACGLTVSKPSEALKFFQSGLSQLTSILLAYPVVQTDKIAKLLEAATQTGIEFRITIDSVEGINAVERAAAASGYSPLVLIHIDVGYHRVGLEEDDSRILEFAQRLHESKSVQFAGILSHAGHAYGCSSVDECAAVAETERSIMVRIKSAIESLGVPVPTVSVGSTLTELARKNFEGVTEIRPGNYVFLDRTPVRMGLASVMDVSLSILVTVVSTNHRYFIVDSGSKVLSSDAPRATQKNTFGTSCYGLAFLEKDFALLNEEPSAHESVTLDGHQIHCWEVKKLSEEHGWLQQVEGMPAPAIGERMVILPNHSCVVANLTDNLFVQGEHPMTWKTVSRGCSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPT4</accession>
    <name>A0A8K1CPT4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPT4"/>
    <dbReference type="OrthoDB" id="166585at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006624">
        <property type="entry name" value="Beta-propeller_rpt_TECPR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19193">
        <property type="entry name" value="Tectonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00706">
        <property type="entry name" value="TECPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="930" mass="103098" checksum="1DED186629EE712E" modified="2022-08-03" version="1">MKPGSRSQNLEEGEGLIRRAPVAHESKIKSKRALAVGASIALLAAGAACAYVAIPSGSDVVTVVPTEKLEADTFVMPTEDTDDDDSLRVDIPPFSDYDRNGDSVISNDEYLFRMGELRDNALRLVETSMLPLEKKNLYTTRLKKNYLTESACVTRLVNRDRKSNGAVTEDRFDVFYTMIKEFCELEDVVIPPEFRATETPSPSINNQVETETPQLVEPTPGPTNPVTYTPETPVPTNPVTFTPETPVPTNPVTFTPETPVPTNPVTYTPETPVPTNPVTFTPETPVPTNPVTYTPTNPVTVPATVAPTTAPSNSREVVIPEGQAIKCSSSDTAVYRYTSGERRWYPSPDIASSWDLNWGKFIIVDCSSIKCGDDMPYKRPAIPEGQAVKCKSTDAAVFRYCDGKIRWYPSPRIAASWDPAWDITLLVDCSSIPRGPDMSLKLPPPIGLPEGQAIKCNPDEAAVYRLTNGQRRWYPDPPIATSWDANWGKFLVVDCSSLPRGDDMPYNTVSPSKVPDGQAVKCDYRRPDVYRFTGGGVRWYPNPEIATSWDPNWGKFFFMDCTSVPRGKDMPFNQPAIPEGQAVKCSSSDAAIFRFCEGQIRWYPSPPVAASWDPVWDQPIVVNCRYLPRGPDMPYKLRSPVGLPEGQAIKCNPDEAAVYRLVSGHRRWYPNPPIADSWDPSWGKFLVVDCSSLPRGDDMPLKLDGWKLLDGMLVQISFDGRFLCGVNRDDDIWCASENIRGEGSTRWRQIPGKLMHIQVYGDFLWGVNRANEIYVGSVIGDPQWRRLPGSLKQITSDNKQVCGVNANDDIFCANTNIRTDPNWRQLPGKLSYVSLLNGRLVGTNSNGAIFTGRAAGDPKWTQLDGILRNAMFDGARICGTNSADDVWCADNGLQSNPNWSMVRGKMRQVATSAGQLYSIDPSGYIFYRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ07</accession>
    <name>A0A8K1CQ07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Delta-1-pyrroline-5-carboxylate synthase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="17">Glutamate 5-kinase</fullName>
                <shortName evidence="17">GK</shortName>
                <ecNumber evidence="17">2.7.2.11</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="17">Gamma-glutamyl kinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="17">Gamma-glutamyl phosphate reductase</fullName>
                <shortName evidence="17">GPR</shortName>
                <ecNumber evidence="17">1.2.1.41</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="17">Glutamate-5-semialdehyde dehydrogenase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="17">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_004302</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>L-glutamate + ATP = L-glutamyl 5-phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 17">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 17">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">In the N-terminal section; belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="17"/>
    <dbReference type="EC" id="1.2.1.41" evidence="17"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ07"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000028">
        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000006">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005766">
        <property type="entry name" value="P5_carboxy_syn"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01092">
        <property type="entry name" value="P5CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036429">
        <property type="entry name" value="P5C_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12 17" id="KW-0521">NADP</keyword>
    <keyword evidence="9 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 17" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="20">
        <location>
            <begin position="40"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="19">
        <location>
            <begin position="315"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR036429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW66537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="768" mass="82104" checksum="A85C3CB9D2CE1FB4" modified="2022-08-03" version="1">MPPRFSSLTAASSPMAQPNNVQGGLYRKRAITRADLHHAQRIVVKMGTSVVSTNGEPALGRIASMVEQICMLKRQGKEVLLVTSGSVGIGRKRLNKQILLSASLRTHVQGNQQMLALEKKKGAMAAAGQIGLMSLYETLFSLYDVACSQVLVTASDFKTAKNRANMRDTMLNLLELDVIPIVNENDAVSAASDGTVFSDNDSLAALVGGEIEADLLLLLTDVEGLYNKPPNQPGAKVIPVFRMETSEFEIGEKSSVGRGGMGSKIEAAQAAINRGVKAVVIASGFKYGIVRDLLNGANLGTLFVSNPGDTSGDVMGADEMAKAARSASRDLQRLSSEERTKVLLRIANELVSQSDAILKANQQDIVAAEATSLDEGLLARLKLTKAKLETLADGITTIARSDEPIGRMLKRTELASGLILHQETAPIGVLLVIFESRPDSLPQIAALALRSGNGLLLKGGKEAVHSNAVLHKLIVDAVEAETKGSVSRNVIGLVTSREEISDLLRLDDVIDLCIPRGSGSMVAHIKKNTRIPVLGHAEGVCHMYIHSEADMGKAKALAIDAKTDYPAACNALETLLIDEALVNDGRAKELLSALEHVGVTLHVGPIADRLGLATIKSRKTTNMSMEYGTKNLTVEVVRDLDGAVQHINQFSSGHTESIVTENHEAAEAFQQGIDSACVFHNASTRFADGYRFGLGAEVGISTGRIHARGPVGVEGLLTTKWKLTSESGHTVAQFTSNAKNPEPLRYTHKKLELIAQEKSNARPKSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQR3</accession>
    <name>A0A8K1CQR3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014614</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQR3"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF69">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="3">
        <location>
            <begin position="121"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="2">
        <location>
            <begin position="218"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="39977" checksum="D4BB6FA3B409A179" modified="2022-08-03" version="1">MRDVSKKNHPDLDQLSLFNDQSAANPEEATVNIFTTFVTQVAGVEAPYLAVASMKHLIKVLVEQPDDYNSKYSMMNLKLFHNAVEHVTRIFCIFGNPGVVALKCINFPSRPTSALKTWGMFLIAGISGLPLVCLITDSQIVNERFLVYINDMLSLEWIPDLSPKEDIDGLLGALRNEAKANGVPDTMDALVNSLLPRIRINFRIVISFSPVASKKKKEEAEEQLSWAMGQVAEVPKRLEQIENTLRQAADEKIKVEQMKESSESRPLPADKLLNGPASENECWGIEIEQLKNSGVLVVGNSLLAATFVRLANAPDDIMSDMPLIESLEEPKKNLDLSQAQSRDRSRDQQRARAVSYRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRR1</accession>
    <name>A0A8K1CRR1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRR1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="324" mass="35898" checksum="88A6119234A0D999" modified="2022-08-03" version="1">MTTFWPKVYASEAALAAHEQPLEGTHEITELQGTPEACLAIVVPYRFIKRRIVWFDLVDNFGMSLLESVQCIAVDPMIDIRRFREAALVEVKAALHEHARSFNVAVFASRNSLESNQGPLPLDFPLLDTQGDGRGRDGHLILVADNVALKPPTTIQDVNYNLVAENGMPLLDSPQLVSLPSDSSFLVVRTAVFKHIRHHLKVEAVEANLTLYVNNEAFLRNDSLPLHKRLSLACTAVLVVVQPIALKPSEVYVDIFEDTGVMMLASPLRVLLSGGSTICDVRDAAFEHIRERLVKSTIEADLVVFEDQDAYTAKQPTPVEHNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRV9</accession>
    <name>A0A8K1CRV9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRV9"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="35852" checksum="C3DC3FB18A67EA92" modified="2022-08-03" version="1">MSPAATTLPTSFRAYVAQGFGPFQDNIVLRSDLTHAPLQPTQVRVQVFTAATNPIDHVVIETGSVFFPTAPSTDRPLRLGFDGAGVIVEAGQDVTAFNVGDEVVVLADFSCMSTFGEYLALDTAFVAHKPKNVSLHQAAGLPLAGMTSYQALLSAKLTAGDRILIIGGSSAVGAVAIQIARALGASFVATTASTRNLEFVKTFGPDQIIDYTQEKWGDVLAPHSIDVIYDCNMEPESWAGDAQRVLKKNTGRFVTADPNYKPNESPIGATCTTVYATHNQEQLEFLLKLASEGKLHVPINSVHSFEELLEVLTFQKSKKAQGKLILDIVSTKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS09</accession>
    <name>A0A8K1CS09_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS09"/>
    <dbReference type="OrthoDB" id="72787at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="516" mass="58169" checksum="4D7A6D8C00D33BDA" modified="2022-08-03" version="1">MELIRLGDAHEYVGTARNFAAVVQQIAVNKRALIQRQQRVSTYHVLHLADPSKLFFKLTCWGDTPPTLAREDHDGEEISLRVGDIVLFSGCVIKSFRGNIDAQFTRQSSIQLLYRRDRYFNTRAVRLKDFYPMIEWYKQHRHLFLVMTEHEDSASVTAHNSERSHQSNNGTPFLRIRELREDIVASLRVHCVEGKSAEEQDAPPTRSASHSDVDGVLLHEVVMKDKWHDTMVLNLWDQYADKRFVARLLAHQGRLEVCGLVISLNQLSGRLLANTTPQTEFRFIDSDAVQTNDADLSTFSSIDAMESSTNEGKRLVLDHVTIAQVGLGHLLGHASRVEPSYTPLLVECYCAVCEQTLPVLDVQTIPQLYGTCPSRCHVKNGAKDRSWRYRPLWMVLRDAHHQLRVHVPSRVLTTLYSNIDAARLIDTSSPETSKRQSFSARFAVAQLVNALVSNSAQTFRVEVLRSTKSISSQSFRLGLHDSGFSAEDGDHDAATSDHKPYTLVTIQASASSFLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG8</accession>
    <name>A0A8K1CSG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_006207</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSG8"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="16">
        <location>
            <begin position="64"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="325"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW68739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="49481" checksum="99D7DBEBE6082549" modified="2022-08-03" version="1">MKLDVTAMRYLTKEHFRVLTAIEMGMKNHEIVPVELIGSIAKLRHGGIQKILSHLLRNKLIAHDGSTYDGFRLTYSGYDFLALRVFLERGHIVGLGRQIGVGKESDIFLATQEDGTEIAIKFHRLGRTSFRAVKSKRDYLRNRKSASWFYMSRLSAMKEFAFLKALHDRDFPTPTPIDHNRHAICMSLVNGFPLNQVRRMANSKDVYEQAMSVLVRLAECGLVHCDFNEYNIMVGETGKITMIDFPQMISTSHPNAPELFDRDVHGLVKFFSRLQGGAYTPDSVPRLDEIVADTTSRLDVEVEASGFGGEYGDHVKDLSMFSAHRRNDSDDEEGDEDDENENEEGEEDEEALAEQLERVNVGDDNEHSDAGADDGEGESSEEEGEEEEGTNSLNAETEFIKRRVQKDIKGRGKSQRRSTRNAAKLSVKGRLYHKDQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSN4</accession>
    <name>A0A8K1CSN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007672</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSN4"/>
    <dbReference type="OrthoDB" id="2139348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051724">
        <property type="term" value="F:NAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052465">
        <property type="entry name" value="Mito_NAD+_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46131">
        <property type="entry name" value="SD08549P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46131:SF1">
        <property type="entry name" value="SD08549P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="68"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="233"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35780" checksum="5DA4E9FDDDC1318D" modified="2022-08-03" version="1">MGFAPVVEDQEWRKEQQTKRQTLEAHGLVGTPSVSPIAAELTRVSDAPTNDTHPASLLDPVRRYSRTHPHLREFLCGGTAAAINIVVTFPLNKVMFRQQLLGLNTWSAYLNVKSEGIRMLYRGVKPPLLQAAVSKSLMFGLYNWYDELLVEQLGNQTGIHLLAAFLSGTTEAVLAPFERAQTLLQTPKFNGHISGAYDAILHLNNKRLVLRTARPIARVFPFQRLPKCSRAERFRLWCHVGAVISTVCFPINVARTRMQSIYGEPFIGAAEAIRLTYEERGRNFRRVYRGVHMNFFRSLLSWGIINSAYERLKTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSS0</accession>
    <name>A0A8K1CSS0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSS0"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="102"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="78099" checksum="05A08FA524C1FDBF" modified="2022-08-03" version="1">MAPLGAAPAMMAASRASSAAHGRMPPTQGVAFKVQSKSAVALVNERRIEFVRAKNARTIGKIDEATGKLVTEGAKKPKKDVIVEPAEIERLLQWKHSRKIGPGFANLGNTCYLNSVLQCLSYTPSLVQYLLTKDALKTFAVTGGNTQQNGKHNNALMHKKPVGQGFCGVRVISRLLQSIHGNSASTGRVLQPKELVMNIRHISKNFRIGRQEDSHEFFRLLLDAMQRSCLRKAHIKQESHPAAATTFIHRVFGGKLKNSLKCAKCNYVSERFDDFLDLSLEINNGIQSVNGAIKHFTAVETLDDRNAWKCSSCNQPNRAEKGMTIDTCPNVLVIQLKRFDGMFGKIKKHIAFETTLDLSIGMQKTCADRQRGRNRYELHAVLVHAGFSTNCGHYYAFVKGSSGQWYEMNDDCVRWVSLDTVLQQKAYMLFYSRVLPKSEQPPPVVKTMEPESAPEPTPVAKATAEPHKKAEAVSKGPELSMNGFLTSLKTDLPTDEDGDVEMGERVAPAKRRVVTYQVTVPLKHKSLKRRLVPVFGGSVGKFSRFQIAKWKPAAPLSMTTTVDETEDMTPAVTAVPVAPKTPELPRPQVESVPINPRDLRNFGDKNAALYGKSVAQWGEDAASNGAAENGVAMLDSALEAQHERVLKQMKEADWKHRKAQRKSSWDEALDYGKTKKVKKRKDFVANEGTVNAFQLALLRKKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSV7</accession>
    <name>A0A8K1CSV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSV7"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000021">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="132" mass="15024" checksum="0D5BCCF421AB3755" modified="2022-08-03" version="1">MAANAPNEIEEMIKQLKSKPGFSSYILMNNDGIIVKHENIEYKEAVMHAYHVLSLFGRTKKHIQKLFPDPNESELDWLRLRTKLHEMLISQHLRFTLVVIQKAEANDLVGDGATRLEDVVVKEDEKAVAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT22</accession>
    <name>A0A8K1CT22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001538</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRP40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT22"/>
    <dbReference type="OrthoDB" id="340500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22526">
        <property type="entry name" value="KH-I_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05790">
        <property type="entry name" value="S1_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000112">
        <property type="entry name" value="Exosome complex component RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000038">
        <property type="entry name" value="exosome complex component RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000073">
        <property type="entry name" value="Putative Exosome complex component RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049469">
        <property type="entry name" value="RRP40_KH-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041054">
        <property type="entry name" value="Rrp40_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037319">
        <property type="entry name" value="Rrp40_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18311">
        <property type="entry name" value="Rrp40_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21262">
        <property type="entry name" value="RRP40_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exosome complex exonuclease Rrp40 N-terminal" evidence="11">
        <location>
            <begin position="56"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="10">
        <location>
            <begin position="190"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="274" mass="29940" checksum="012AF9C9CEA9705B" modified="2022-08-03" version="1">MAGKRKADEPIDATADDEASRFLEDAQRQVDFLFSPTVVLPGDDVTEILTKTSKNVRLGAGLRLLPGDRIVCTNAGVLRYRPPNRYWVEFDHKRYNVAVDDGVIGVVTDRNAEFYRVNIGAASSVTLGCLAFDGATKRNRPSLRVGSLVYARVLKTNPDMEPELTCEASANMTKKDWMTGLSVYGELTGGYVFKTSISLAKKLLQDDSYVLQALAKSIAFEIAVGLNGIVWVNSRATKHTTVVTNAILNSETMSPSEIDVMVQQLIATTSRDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUT4</accession>
    <name>A0A8K1CUT4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUT4"/>
    <dbReference type="OrthoDB" id="532630at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF1">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="87" mass="10221" checksum="129ECBF340E87C30" modified="2022-08-03" version="1">MHPSLEREHPDCQDVIHALNTCHDENPMAKFFGACNDAKNELDKCFRAEKIRKRTENLERARASDAYVRQKMKEHRERRAQEQAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVC1</accession>
    <name>A0A8K1CVC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein 44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVC1"/>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="168"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="269"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58853" checksum="B5C715DF4E82005E" modified="2022-08-03" version="1">METAMATTLHERDGDGRGTRPALLHEDSTFMVDEDFYDAQEHVEGEAARQKDNENALRPVTPTSRDEPKTSEEEKYVVRNKDTGEEYDIRDLVQQPVETTIFPNNFAPPTSEDESRRAKQRRPSVSKLKIKFGIKGRGKEATKRNHVPMLSTKKDKRDFDDLCIAQSISKHTGTIWCMKFSHDGARLVSGGQDTILRVWKVAISSGVREAASGDGSEKVIIEPEPEQSYQGHTMPIVDVSWSRSNFILSASMDKTVRLWHISRDDCLHVFQHPDSVPAVDFHPKEDRYFLSGCFDNKARVWDIPEGCVVSYMHTPAMITAATFNPSGTRAVVGLLNGQCFLCQVSSQQQMTYFTQIECRNSRGPMKKGRKVTGIEFDPEGKYFLVSTNDSRMRLFSVDNYSRICKYKGLMNDHLQIKGRFSQDGDFVVCGSENGHVFLWNKNSSLALKSGKQNRNSSYEYFCAAEPPNGIVTVALFAPASTYAMVKSKLEVTDEMQTNPCTGLIVTASYDGCIKFFERSPKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVH4</accession>
    <name>A0A8K1CVH4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVH4"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="52478" checksum="8C50CA49A3E4BD48" modified="2022-08-03" version="1">MRMEASRISTAGSVALVMQPVTPATAAALQYQWTQSFEATVRTDLKHRVLPDPLNDVEEAKPVPWQSVRDLPDRRLMVQRILTLTEKKRAARTGGTPPSSDAAASLAKRIELSLYSRAGSLDEYKNSATLRRRLQSLVSLSFHEAAAAKASPVAVRPGKRARPGSLAPSSKRRRLGAYTANSSLLLGPLSEDCLRTLFGFLDGREVLALRPLNRFAASFLPSCVTTLEVEVARFYRSFVDERAGPSLVQMTNLERLVVYKTTDPCAEPTSVEQRLALHAWGCTELDVTHDNAGELVVQHLASAMESGACRHLKQLQLVSVFTNTSHRNGLRHLCNALLRGSCPDLEDLLLGGNSITDIGTLDVARLLRSRALPHLMRLDLRRNYIGETGLQRVMTALAASPTTELQYLCMGGNLITDNSVSPLIGMLERGLYPQLRFLGLEDNFLSPEGVQSIIHAAVSGGMVPKLHRVANDGSSADLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAH0</accession>
    <name>A0A8K1FAH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_013813</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="16">
        <location>
            <begin position="257"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1055"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW55051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1574" mass="174823" checksum="0E00000C0ADD7E16" modified="2022-08-03" version="1">MATRGERRNPLVKQLVLENDRPAKISHLNFGLLSEIEMMRLSEMRIHSKDLFKMPTREPAAAGVLDKRLGVSNKKDVCETCHLRLSDCVGHFGYIKLELPVFHIGYFKAITEILQNICKECSRILLPPQERETFLRRMRDPRADSLRLMGLRKKISAMCKKTVKCPYCSGINGTVRKITTTTLKLVHEKYRAKSAHDLRNVFVAQFSEAQAINPDIGQHLPKAQEDLSPKVVQELFKQIPDQDCELLWVDPLAGRPEKLILNSVLVPPVCIRPSVAMDGGSGSNEDDITVKLQEIVQVNFALRAALQKGASLKMVMEDWDFLQIQVAQLMNGDTPGLLKPPGAPKSIRGLCQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDQVGVPEHVAKTMTYPEKVTRYNIEKLRRCVVNGPNVWPGANVIRIEGQKFTKNLMYGDRASLADELKIGDIVERHMEDGDIVLFNRQPSLHKMSIMSHRAKVMPWRTFRFNECVCSPYNADFDGDEMNMHLPQTEEARTEAITLMGVEQNLITPRNGEPLVAATQDFLTASYLLTQKNVFFNREQFCQVIATMSDAVDHIEMPPPAIVLPVKLWTGKQVINLLIKPNSQTRVLVNLELKERNYTNNKYMCWKDGYVCFRNSELMCGNLAKKTLGDGSKQGLFYVLIRDHGPQEAARCMNRLAKLCSRWLGDCKGFSIGIDDVTPSADLAEKKEELLQTGYDDANRAIEDYRRGKLSLKPGCNPLQSLESELNGLLGKLRETAGAECMRTLPFHNNPRIMAECGSKGSALNISQMVACVGQQSVGGKRVPEGFVNRTLPHFLPHALHAAAKGFVANSFYSGLTATEFFFHTMGGREGLVDTAVKTAETGYMARRLMKALEDLSCQYDHTVRNSEGSVVQFMYGDDGLNPAFMEGDDRPVDFHRLLDHIRSTLPDAESPALLPFEIRQVAKKAVQRREFQSILPAGRKFLIEIEEFLGSIANQVAKARVSAGIDSLDHPIKTYSTHLEKVFEEEIASTAAAVAQAKSGGNNVKTEKKVKVSTKLEKVTRKTPGRKRLVKSETPVSEDEEDDEDVVTFDTTTYKRKGLDAVGSSTWSKKFKTQKSIAQWRARAAMEGTPEQEEAAWLLSHHVCRLTAKQVEKLLELSLYKYHRARMEPGEAVGAVGAQSISEPGTQMTLKTFHFAGVASMNVTLGVPRLKEIINASKAISTPIITAALVCKTDERSARIVKGQIEKTTLGEIAVHIKEVFARDQAYLSVKLDMEAIEQLHLNVTARSVRNSILNASGIGPRGVLRLLKEQHVLLNARCPDKLRILAPSNYKSARGETRGAYFAMQALKSELPGVIVQGIPTVNRAVINYEETGGKNATKAHHLLVEGYGLSEVMGIPGVDGLNTTSNHIIEVEKTLGIEAARELIASEVNYIMSAYGIGIDRRHLMLLADVMTFKGEVLGITRFGIAKMKESVLMLASFEKTTDHLFDAAVHSRTDAIVGVSECIIMGIPIPLGTGIFKLLRQVEKPIVEQRRPLLQHLKFQCVAHAVKHASQHGGGAPCENRSYEAACVGDPTDIPGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCF3</accession>
    <name>A0A8K1FCF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chromatin assembly factor 1 subunit A dimerization domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCF3"/>
    <dbReference type="OrthoDB" id="79480at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="7">
        <location>
            <begin position="686"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="540"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="603"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="727"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="773"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="879"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="727"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="816"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="922"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="946"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="987"/>
            <end position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1018" mass="111238" checksum="832686B55D820B9E" modified="2022-08-03" version="1">MTESKKASAKQVSIAAFFSPQASKPAGGTRMLTPDKVSASPAKSQETAVVDLSAELSAEEAKTEVVSTPSKRKRSASASAERKQPPAKKKTTKKESVVVEITSTADGEEEEDESPDNDGPVISSRSPHELTPQKEVTPKGKKKAAAKSPKEAASADKKPKKAPARAKKEKEVPVAAPASLEEPKESDEATSATKKPKKAPARAKKEKAEPVAATPETTATTEEVSYGANKPKKTPARAKKEKAEQAVVPPATTETTEDVSSGAKKPKKVPARAKKEKAEPVAATTTPAETPSEAPAPAPAPALNLDALEPAVRARVVSYKQKIKDLTRQCEQYMTTKTNNVIDVMWQEIYGVGLDVDLDPTASETEDSQLKEGWLALSQSEAHTANDEATLVLKRYIARLVQGRNASLTNLKERITTQLSNGSATSSPSLPLEMEIKMLAQRTSYGARPAKANLYEDTTADALWCWEVSNIELYFTDDAQKTIKRMRKQRKRAGQQLKSLSRVVQLLLQTPVDEAKVSTEEAKIGKFVAQVESEVLKAKERERKEHEKASVAEEKKRAEQEKHHAKEEEKRKREQELEAEREQSAKRRKSLVSYFRSIDTKKEDEATEEVQVTRASGGSSNQSTDQEATMARMDAAISFIGEPNAEKITDSADSATLFQRRRALVTAENGAWSHRRHRDAKLGLMKLLQFHENYRPAYYGTFSKRSRIFRRGRRPFAQFRQFDYSVDTDEEWEEEEPGESLSGAESEDGEDEDDQLDYGDDWLAYEDEIEYVDGEGGDKEGESGLFDDDDDADEDEDVPMADDDGSDKKKRRRLVRHDQKGKGRRVVAEHKKQKLTKLEPLVVGPFVCFTAACGDHLTSYRGELLSSPDFESSLMKLARARAEKEEQELIAKEKAAAAAATASPAKSAAKAPSSTPKPAEPKKKKSVKRKIAPQLMTPPASEGKKQASSASKAAPSSSTESPHVPAARPSPAKASPAKAGLDQWLKASPSLQPAPSADSSSSPSETTTTPAPSDPIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCF9</accession>
    <name>A0A8K1FCF9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCF9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="257" mass="29511" checksum="AFBDF970781D4449" modified="2022-08-03" version="1">MSTTESMDEAEAYAELMRRRSKREQLLDLRSTVKELESQLEALREAKKDPTDDLWKSILKTQRKERQRSEAENARLREMLNDQVFTAQNVGQALFRKRTSREDDDGLFDSGMAADTTATNKRAKTHEGISHLEDPAIETQLLSIAHSIYLDVDQILETPLLKSSKAERRRVSEIRNDQKAGMTVMEGVDTVVYPFEYRGVADVLWDVATDVVDSSMALLQERIDHTEGVFTRFYEQAVDLDTWARSFPCQGRRVPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCM1</accession>
    <name>A0A8K1FCM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCM1"/>
    <dbReference type="OrthoDB" id="162287at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="401" mass="45516" checksum="3494A2B4F10A6C88" modified="2022-08-03" version="1">MKRRSPTMAMEREPASLSGHSTEDEVLLDARARSAVDGDGGVPEQPLHEEDDDDDETSDDVHAATESAMSAITEMNGADTPSVKKRRTKNYKWREDMAKKSQDTILVRLPPLEPVTFRTWDEFISTWNEYMATTKTLYRRRSSCSTASWNAKKRFKMYPVPSTFQYATMAYWCTHGCIQPSRGTGVRAHLHNRFTGCTARISADVVFEKSEEGEIEWFIRVRNQISHHNHHISNEIYNCYTNSSSVPDELLLGHPEDVAGRRSDETVSLRRTRSRQNTNRFVHNAEDEDQAAASGAIGGSHEASPDERKMELCRLELQPVLDELRRTPSHIFYKRLQDVSEVVVHLLGKWQQDPADDRRLMEYLPAPGVPGRPATEAVEDHQVHDNGAAPVTTTHVQTEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCX7</accession>
    <name>A0A8K1FCX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCX7"/>
    <dbReference type="OrthoDB" id="74529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42837" checksum="D5BECAD69F35A5B8" modified="2022-08-03" version="1">MTVELLLTSVRALVRTREELQRIPHLARMINALLDHSARWTVPSAARSGFPHLLEYMASRQHVAPMTSNEVVLGMRVAVKNGHLSVVKWFYENLPPTILPGNIMDFAAARGQLAIVQWLHENTKETCTTFAMDRAARSGHLEMVQWLHENRTEGCTTAAMDNAVWDGYLDVIKFLHFNRTEGCTTEAMDRAAWRGYLDIVRFLHENRTEGCTTSAMDNAAWPGHLEIVKYLHENRTEGCTAAAMGVAAIQGHLNVVRYLHENRTEGCSSHAMDGAAFHNHLDVVRFLHENRTEGCTVQAMDGAAAEGHMEVLEFLHANRTEGCSIEAAIGVIDRGRLDVLEWLWERYPEVMNADVLLHRAEIRQRQDVIDWIQARLAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDM9</accession>
    <name>A0A8K1FDM9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDM9"/>
    <dbReference type="OrthoDB" id="168489at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035447470" evidence="3">
        <location>
            <begin position="23"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="410" mass="41872" checksum="7FEF700E4F556247" modified="2022-08-03" version="1">MRRAVCTLALIALAALANQVEAQCSAETCKINGGSKKCDRTKTECPPCLLEKSSFIVFKEYSCYYLEDSGECPEDTTFCGTSESSSGGSLSGSGSMDVTPTPTPTPKTKKPSKSDSASKEDEEEEEEESGSGSNTPKPTKKTPKPTPTPTPTPEETPTPTPNITLTPEPVQTSSAANSTATTSEESSGSKLPLIIGIVGGAVVVIAVLAFFVYKRRQDDDDSDDEDYRYNNPPTKPAASTYSSNPRGPTSPSGGANKYGGAATAAAAAVPAAAPYGGNQYGGGNYGGANNAQYGGANNAQYGGANNAQYGGANNAQYGAGAAYGAGAGAGAGYGAGKYGNDYGSPSTIDGSDRNMFANDFSSSHISASAAKGHSSPNGSSSSNDKDAWGNAVAQPQTREKRTLSNVSVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP4</accession>
    <name>A0A8K1FEP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP4"/>
    <dbReference type="OrthoDB" id="160868at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="214" mass="23171" checksum="A8858B5108330B5E" modified="2022-08-03" version="1">MASTDRDADLAKVKAAVKNMFYGATLTGGVGAVWGAFLATARNESVKFYSASMGANFFLVSSTFLAMEEIIADKRGKRDLTTGAASGGLTGGFYATLVGGRLRGLQGAAAGAAVGAAVIFGREQFHKWRLTKAVERYEQKYGTAPAVYYPNTDILVETKSPSRELRFPSLLPSSIKVTDEEIERRIQARVEELRRQEEEEEDKEGKAPASTDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP5</accession>
    <name>A0A8K1FEP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008701</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP5"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34495" checksum="3C288CA5051BD040" modified="2022-08-03" version="1">MQILREEGFRRARPYQATEPQIRTLRQHRYEYFPQWRFFEDAHNEYLLTDFAHNGSLMLYAKRQIDSYCMEIVHLVSTHTNATLVGFPVVTAATKLWREEALFIFAGIVEAVVYMHSKGVCHLDLDVHNVVIDSLGCPMIVGFGRGEVADEDGLVGRSRPILCKRPYAAPEVYAHNRNVKPSSGVDGRAADMYSLGVILYWLLFMCPSEGAIIDPVRSDPRWLLNLIHHASGNFDSHEDLNCAICQSSIPLDAEIIQLLLALLSKNPADRVSAADLSTITRTLYNQLHGDTSTRNQAVLEELHNCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF10</accession>
    <name>A0A8K1FF10_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF10"/>
    <dbReference type="OrthoDB" id="3794857at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039437">
        <property type="entry name" value="FrzH/put_lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12893">
        <property type="entry name" value="Lumazine_bd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="136" mass="15351" checksum="EB6012513265D292" modified="2022-08-03" version="1">MPRVEKQEPTQQEIDAVTAHVDKYGKSLIEPDIDSLKSCFHDEATIFSTVGDQVIGGHIQWLYDNMKENGGITGLEYKIKVLSVTRSTAVAQIELYRESPEYEITDTLALIKLPSGEWTIVSKIFHVYQYNMTLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFX3</accession>
    <name>A0A8K1FFX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFX3"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="51189" checksum="F2BA34B49BE3634E" modified="2022-08-03" version="1">MTLSAGATYGAMIATLVAVAIYAIHASRSMEVNNVKNFLSAKNSQTALRLAWCFFSAGMGSWTLFSFPEIGVIAGSWGVIGYTLSGVLGLVALGIFGPFSRSVLGDGVTLTDFVFNRFGRVMQIYVGLVSVFYQFISLASELTTVGDLALILSPNSEPAIPIIAVAVVTNIYLIIGGLRASLATDVWQGIGVVGLLLIVCVAMFAHVKVPEGAWGETKVAAFTTTGFETLVTLCIAVTASNLFFTGYWQRVYSAYDDRTLYKATFFACLIVIPFTVILAISGMVSYLAYPDGIYFFAILVDMGKFWQVLVAMVVASLASSVADSLQIGIAAELVTNFPSLTINHARAICVLLNIPAIIIALKHLNILELFLIADLLCTATVGPMLLGIWNRAHPTGAIAGCAMGLLTIFVNGWVVQGKFVGGFNWFLLPEGLYSVNSMITFILALVIPTVTTIVVSLALPAQYPARAAYLPANSPTVNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFZ9</accession>
    <name>A0A8K1FFZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFZ9"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426006" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="386"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="713" mass="79108" checksum="C10F850D73BEAA02" modified="2022-08-03" version="1">MRPSFAAAAALALAALSLRVDARFVVTDLRVVRATTHENALELCQQFSPSHFTTGIDWTSESTGVVVQLCQRREHVEDLKGSDRQVLRQIGVYPACPASMTEFYKPRDGVAVCTRLARADDVLPAFDYVSDVAVTVERNYNNDGPGWTTIPISLHGSQTFFQRLLAGSHRGVFLSHERPVVPITALEVLHNVAKDQAATWCSSLFGVQWQSAGTGFLDQNDDDKTVLCVQRDPNFVNAFAKLVDIAVVPTSQSCPEGFVLKQSLTSSVSLCSKWASLYANTVEDSVFVADIDLHRVDTANEDYSPTDREFLPGNFTLLYPEDLNAASSVRSADARAPVYLFSRLFVPQRFPSPPPLDKAPLNAVVNLYLDRQKDQQLLANRTTLSFKVLQLADLHYTGDPTHACRDKPVGMATCSEAVMTAFVNNLLDLEKPNFVVFSGDNVQTFSTVRRKPAMDAVMSGVEARKIPYAMVFGNHDDENGFPREEIVQIAMSGEHSYTQRGPVEVDGVGNYELSIKTPVDGPWGPAGTDIFRMYFLDSHAYPDTSKYPSVSASYDWVKPNQIAYYRQLSTAHGESPVPAIMFFHIPLLEYGTNAMSRLHGERYESVASSDVNTNLFNTLVERGEVKATFVGHDHVNEYCTLREGIQLCYGGGTGFGEAYGRSTFARRARVIEWSLTDSGERTIKSWKRHHDDLLHRYSEEVLFSETVADAQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG16</accession>
    <name>A0A8K1FG16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG16"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="117"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="332"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="47252" checksum="AD037FF13C4637F2" modified="2022-08-03" version="1">MEKVLPTVDAALKQPQAPKSLKHKSKNKRPSPTYAAATGTPASGAGEPHHHHHHHHHHHHRSEEEKLRELLTSKIAEIEVGGDENLELPIDLTGIYQDESVPEHVVSAMQTVVDDAELSAEDKVEKLSAQLKKASEEMSLLQKKIGEINARCIVMKQRKSAVTTELAKVNGSKGKLEQLCRELQKQNKLIVTESRRIADEEDQKRRELSAQFQKTIEEVSAKMDQQGKDYVTSLKENENLQQKLKSFLEQYAAREEHFQRQLEAKDLTVQLAEAKLQHQVELTHREAEKAKLTMEKAKEFAEREVQLQMQLNGYSEKFDVVQDTLAKSNEMFTTFRAEMDKMSKQTKKLEKENLALKKKCDEYDRGAITSIQEQVKSAEETQKLLEKIKKLENLCRQLQAERKSLQERADSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG18</accession>
    <name>A0A8K1FG18_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG18"/>
    <dbReference type="OrthoDB" id="76789at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="187" mass="21220" checksum="E651DE251C3185D8" modified="2022-08-03" version="1">MSRRAMAKANAHVHESDDDEAPEVVSKASAKEQALERLRHEEEARVTAPTRRKRKAPTAREEIEATEDADEQADGEEEEAPELPADVLSALATRDEEEREENELEAKRERQRRKRAAAMKQRSHIRDFGTVQVQTLEALDASESRKLNDAAVAFLERKSAPQRARMNVLEGHPSLFTKKQKTRAARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGV3</accession>
    <name>A0A8K1FGV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat domain phosphoinositide-interacting protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGV3"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41780" checksum="26361E1CF2E19ECB" modified="2022-08-03" version="1">MTAMNLSREQQNELLFVGFNQDAGCFACGTDTGFKIFNCDPFKETFHRDFSNGGIGIVEMLFRCNILALVGGGRNPRYPPNKVMIWDDHQSRNIGELSFRSEVKAVKLRRDRVVVVLQNKIYVYNFADLKLVDHIETIANPKGLCALCPSSSNTVLACPGVSRGTVRIELYDLRKTTLITAHEAELSQICLNLEGTRLATSSDKGTLIRVFDTQSGQIMQELRRGADRAEIYSICFSPNSQLLACSSDKGTVHIFALTAEGSGTNGTFSTEQSSIAPATPVPTPGNPYNSNGRGEEEGTENSKSSFSFMRGFLPKYFSSEWSFAQFRVPETRTICAFGTEKNTIVVVGADGSFYKAVFDANGECQNTSYSKFIHADEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH72</accession>
    <name>A0A8K1FH72_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FACT complex subunit SSRP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004501</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the SSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH72"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13230">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13231">
        <property type="entry name" value="PH2_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000001">
        <property type="entry name" value="Fact complex subunit ssrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.220:FF:000004">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.220">
        <property type="entry name" value="Structure-specific recognition protein (SSRP1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048993">
        <property type="entry name" value="SSRP1-like_PH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000969">
        <property type="entry name" value="SSRP1/POB3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035417">
        <property type="entry name" value="SSRP1/POB3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024954">
        <property type="entry name" value="SSRP1_DD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038167">
        <property type="entry name" value="SSRP1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF1">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21103">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17292">
        <property type="entry name" value="POB3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03531">
        <property type="entry name" value="SSrecog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00887">
        <property type="entry name" value="SSRCOGNITION"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="11">
        <location>
            <begin position="339"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="462"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW59432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="61069" checksum="F0DA4EE4EB0A6543" modified="2022-08-03" version="1">MAETTLNNVFWGHSDGVLVLSASGLLWRSRSTEAQKKLTKDDIVTMLYTPIGDKNHHIKVYQKGGKYVRFTGLKGKDIELLKKHVETHFDRELEQEKVSSIGGNWGEMKFEGPNLNFREANTSVLEIPLELVSQCALPGKNEVELQFHEDDTVAGDEETLVEMRVYLPPGDGTDEMLTAEMFRDEVLQRANIRNVTGKAIVELDEAIGTFLTPRGRYGIEIYANFLRMHGKTFDYKIMYSNINRCFLLELPNGINTAFVISLEEPIRQGKQGYPHLVLQLSKEDVHIDVNLSPEEIKKYNGNIHERMSGALPQIVATLFKFIIGKKVYTSGKFKTHSGDRAVKCAVKAQSGVLFPLEKSFMFIHKPTTFIRYEEIEYIEFQRYAGQSGSSASRNFDLLVNCKSVGGEPAREFLFSAIDRREFPELSQFLTSKKLRIRNLKEPQAESGGKKRGFNEFMEELGPEEGEIEDDEESEDSDFGPGDESEESGGDYSDESLSGSGSDGEEDEDDGAKKSKKDKKKKGGDDAPKKKKKKVSKDDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHB4</accession>
    <name>A0A8K1FHB4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHB4"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000099">
        <property type="entry name" value="Lactase-phlorizin hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035466594" description="Beta-glucosidase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="58711" checksum="0F17EE5341BE8282" modified="2022-08-03" version="1">MLKTTYLAILAALVLGKPTFATYCDGGHDPVTPTPITPSLPPSDGDGGNSTTKCFPSGFMFGTATSAFQVEGGVNATGRTPSFWDAMCKSGSGLQCANVADDFVHRYKSDIQLLKADGYGAFRLSISWTRAMTWNNATGHMEANPEGLAYYHSVIDELLANRIEPVVTVFHWDVPLALYQLGDFLQASIIDHFVEYSDLVYREFGQKVKRWATINEPLSYMAILYTRSASDSDEYEAAHNLILAHAASVQRFRELQAGGTVLKDAQIGLVVDSFGIPMNASDPADVEAAERYNQFEVGWWMSPLATGDYPAVMRERVGSRLPTFTEQQAAVVKGSYDLLMFNFYGSSLITDCASASSQTNCSTLSAGHHADMGVDSSQFPPEAVRASGSTCSSRFGYAPSYLTAIEWLHKQDPNTGILLTENGWCGNATIDNQDQVWYYRTHLQQVHKAIHEEKIPIVGYLAWSFLDNYEWGQYDARYGLYHVDFPVNIGSPDLYTVPETSLTRTPRSAAKFMRTVATTGCVEVKPEDTKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHS7</accession>
    <name>A0A8K1FHS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Regulator of microtubule dynamics protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Protein FAM82B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000119</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts with microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHS7"/>
    <dbReference type="OrthoDB" id="69711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097431">
        <property type="term" value="C:mitotic spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049039">
        <property type="entry name" value="RMD1-3_a_helical_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056:SF16">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21033">
        <property type="entry name" value="RMD1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="300" mass="33889" checksum="6F42E599E6747F09" modified="2022-08-03" version="1">MLQFARLRSVAPRALRRLNRTPSVSARFASTLRSAQPLSSAPPSISAFASVLAVALSGSVAFSLAKMSESAEAIKAEERFYDHSYGRRQLYEDLKAAYQANSEDIGVMWRLSRAAYDVSNLKATPADEKKQLIYYAYDVIQKALEKTDEIAEVHNWYGIILSSVGDYEGTKVAISNSYKIKSHWEKAIELKPSKPTTYHLLGRWCMTISDLSWIERKAASVLFGSPPESSYDEALKYLLKCDELDPGSWKKNSMLITQVYYKQRNWALAKEWAQKTLDVPIKSEEDQTVHEEATALLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIA3</accession>
    <name>A0A8K1FIA3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIA3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="28529" checksum="DF3CB6E6C2AC7022" modified="2022-08-03" version="1">MRIASSVLNNFVTKKTDGTKENLLDQTQFLNLAREAGIAAVAEPETKKALMGMIEGGLSVASASGPYGSGIKTLIVQIQDLVVSARQKSPKETADKMKEAVMGTDIMVKSVPDVAEKCFNAKMPNALKNRDQFVATIHAITDSIIETLEGEESKRLTPKELVFSVAELGLNIASVFDTTGITGLFAQATCEPTSITTPIQFGPGDAQLGPKTVNRAFEGSSGEWLQAKSNVVQATFTSKDSEDVEVVIYSGGYDYKTVQVPKASTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIC0</accession>
    <name>A0A8K1FIC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIC0"/>
    <dbReference type="OrthoDB" id="165010at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="598"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="687"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="826"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="858" mass="96161" checksum="C752B089D1A2450B" modified="2022-08-03" version="1">MERIRRGEKQADLAKEYNVSRAAITNLKQRRQMLEMLEQNQRNMQLAQLGASNSNANHSGRDKRRKLSTEGRHVESENGDKDPGRDIEGGDSDGAHSIDSTSVKIEPRLPVPLPQRVHHRQVSPPTISRVLSTLLDASTADDVFQATAQRFIRLVLEETIGRSFAHAQNQAQTTPFAPCVSTCGSKEAAAMGREFQVLEPSAFVVSSATIDKQDDPEGVVVSVRLPREALERRPVMLFFDDIDVAGGAVNEQHNDSHRGDDPIHRCLLYVLSLVFQGVPEDQIFVVLCLCDAALAEQLQQRFPKVHVVTARFLSSTETVEDLHHYRVRLRAMIDEQSKQRDGNNQNVTLATAIVNSENEENVLWFLETCDEAGIVLPGRAVFCDRGKILGAVKKLWKDKGLLVALRFCTVHLLRNLNTMFKLRNTAFQNDVWKFQATTTAREYKSTFEYFKDTYGEGPANYLDKIGENNWTVYGNMSSFVPKHKPDEVPSYPLPPFGWRSTNFVESDNSALLAHGVRDCSPFEALKSIAEVETTRASNGDILAQQFTKRKLNLTPYARTLLEKERSSAGAYIVKRCSEDIFYVVSTKYTAKNAAEKIREVRLAKSANPSCSCPTYDQLRIACRHIIKAVGSKVRLQNLKKSAASPREKNRLIYNAFHPSYLGQTYSRTLKGKCIKLSLLDVHKPDEALKSASRSKSIGRPPKKRIASSGELPGSKGTKGRKCSVCGGHHHKDNKKCKGKQGPVVLNSTLKAHPHPLPAPLQQLETDVTPSDEEGNVDWVSDHSFEPERDIADHSDSECDTSHGEEFNPALVGEFLDEFTDDFGYEHEPRSEFTGDFDHEHEPRSECDRHSLEFLLSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIF2</accession>
    <name>A0A8K1FIF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIF2"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF296">
        <property type="entry name" value="MEIOTIC P26, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="6">
        <location>
            <begin position="313"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="6">
        <location>
            <begin position="417"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="624"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="693"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="493"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="660"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="701"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="762" mass="83658" checksum="8F623957CC19151A" modified="2022-08-03" version="1">MVAENEENGSLEGSEMSASLARLRLFLAPHAGSKLDADGGPDHSVAQDGSCRDTKDSVAHEDTEDRPNDSEPLEDLSADLNVLAEQLGESTDESDHLRPESDGADPKPHEGFSHNEPDITNAVPAVGAVATVSPLSTASSEFARTRHLLQCCLPGYRVHDDMVMWDMKNPALMAQYEEHASGLLELESWVAVDDLSAAMGETHSYAFTQVNDGHSAMKFTTGDIQIESSGATGSKVRKQLVLCKIAVGRSVVVEREGEAQQKPLPSGYHSYYIRRSHDPNPPHGYCHEYILTNALQILPQFLVRFSVSAIDNPSASSCALCEKHSATVSCKSCEADLCQKCDQDVHSANKLVSRHQRMPLRHQEPTSESRNTRRRSSTPLTAGASMETNQTAIESRESSDIDVSATVAKLLENALTESQSGCPSHSDKKVEFYCSVCCVPVCVNCKMIGDHSVGEKGAHRLLSITDAYERSLRESLKTDPLIESRMTVIDSKLKAIEKCKKDVETNREQVEAAIREQYENALARLKDEVQKKIDILDGEALEYRRQSEHIDWLDDSLDEIRSSCSVVDFLSAWKEHKVLRTEQRDFPTASFTSSGDRVKGDLQLLGRLQVIQGDRFDAQAVTPLVEDQLKSSNDGGNKPPMSTRRTSDSEIRRKLLSMRSLPSSTASTTAPSAASMTLSAKGVKMIEEIRRELLSPGRPGSSLTSPNGKSPLSNSTATLRQFSINPVRKKSASASPDEYQVDPWLTLLRRHELTRPPASTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIT3</accession>
    <name>A0A8K1FIT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIT3"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="490" mass="56766" checksum="E9C6A447934BB52D" modified="2022-08-03" version="1">MAEKHRDDKPADFLLPESVKNWFTHIYTHLISGNVTEMARLYDREFHNLTNNYFKQTTWPEPAAIESLVDEDPTFLLLYKQIYFRHMFSKLQPTFEYKVESWNTYCAIFDGILDQSLELDALPSQWIFDIVGEFVYQYQSVCQHRAKIAAKAEAENAQYEANPDVWSTTKVLNYLHALVRYSNIVAILKSDDAEAVKAPSETIKELGYFALICLSRAHVLYGDFYTSLKLLEPIDFYNKSSRAEIKKSTDQIHEKSPSCHVSVFYHMGVAQLMLEDFAAAIRSFSTIILQVHRSRNYYARFADYEQLNKLTEKALAMLTIALFLCPGQRVNEQIHTLIREKYSDKQSKLQKGDFSVLNDWFSFASPKFVLPNVPKSEKSRGSEAAQLQLKSFLAMVERQQHVASLRSYVKLYRSIDLEKLARFRGVEVEAVRAELLAYKIHEASRKSDVHFYLADDVVLVDDDVSNQRTGEFFLNHIHRFARIVDECAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ10</accession>
    <name>A0A8K1FJ10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DIRP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ10"/>
    <dbReference type="OrthoDB" id="2339771at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033471">
        <property type="entry name" value="DIRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010561">
        <property type="entry name" value="LIN-9/ALY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21689">
        <property type="entry name" value="LIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21689:SF2">
        <property type="entry name" value="PROTEIN LIN-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06584">
        <property type="entry name" value="DIRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01135">
        <property type="entry name" value="DIRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DIRP" evidence="4">
        <location>
            <begin position="214"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="643" mass="72438" checksum="15FF7B774ED24673" modified="2022-08-03" version="1">MLASDRVLGPRWSVKELRTFYILLKAYDKQWERLEERLPSRTNAMIRGLYDMHRGYLSLPEASVEGFCTIMMDHYKNMDELLGVTGRQEEVEAQTVDSKEHVVFGLARLQVEEHQSAATTPSGTRVRTSSMKEEGVNQDTRSKKRRKLDRFLARDDHASIDQSSVDPKQHGTPQHMRKTTFAKSPVNRRRQWFQGPTHVKLATRKFDLPWFYWFYSYVDVDFFLNNEFVECLHRMGLGKITTAARPIWSSVRASMGRPRRLSPLFLAQEKEKLRNYRTLKRQSDISPDVQANGWPYKCPMKLKTGVSVLARLEHPRRFAVGVIENYSLKDGVCKVRLDSNGSRVCSLDSVMLLPESSQTTVPIIISKSPVPVKVDHAVAVATDTKPALVSTNDKLTTILLVKELLKRKELIVNAMTTMNDQARIRREIGSRNSKGSTDQAKEEDKTVFQRQYAWLVVNLDVTNRYLRSALLRLQDITNGTKANSSALTAASNDATSVAAVPVSTAHTSAAPLISDVQDSATLTLDHMRWAVNFLAVSRKKSGELVDGMENTREPSEHANAELLPETKELIANCVTLMSVLRRGSSPDIPPLITQKLLERLFELLEPNFEANMDLYAELRAAAEGVAVMQQQTSVGGAPTPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKK1</accession>
    <name>A0A8K1FKK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phospholipase D</fullName>
            <ecNumber evidence="2">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012316</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKK1"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09105">
        <property type="entry name" value="PLDc_vPLD1_2_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479316" description="phospholipase D" evidence="7">
        <location>
            <begin position="24"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="584" mass="66148" checksum="6D6823F94711EBF1" modified="2022-08-03" version="1">MQLARVVSFLSCVLWTLAPEAQAARAGITCQKRDNPIKIVAQLCMCEPCHVCEYSLTKKSCGLIKDNGMVLSDGSENQPVQPTLDAEQWFLTEDEITQSRGGVPRSDMQVYSTGNKVHVFPAADTLFLSVYDDIERSNANDTIYLAAWSTDDITFDPINDPTGERTSFKDIMGRAINRGADFRALVWRNMLEKKQNVKLRDIINSLPKPTEGGSTRFIFDDRMPELASSLHQKTLVLRQQNKLIAYIGGIDLTSDRWDTVRHNESEFRKKLNIRRNHEGWIDGHYRIEGPAALDVGANFLARWNSDFKPMDTIVSDVIREFKNPEYAKLPDYTSKGPLDLTSDGKQAVQITRTFSCKYPHYKEFAPKGEKSILQARIKAIKMAKNYIYIEDQYFILVPELLEALLEVLPRIQRLIVVAQRVPDGMKPTGYEKYFYDMVAPIQSRYPNKFQLYSTKEALNVYIHSKIVIIDDVYVSQGSANWNRRSMTSDAEIGANVVDTDLVTSPEGLQVGKVVRDFRVAKFAEMLGKSVDEVAPMPLLEVADLYDTVAADPSSLIERLDIHEHSSYAAFNDVVRQKVDPDDKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKS2</accession>
    <name>A0A8K1FKS2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009486</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKS2"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14335">
        <property type="entry name" value="UBA_SnRK1_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="66"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="9">
        <location>
            <begin position="342"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="395"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="493"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="562" mass="62091" checksum="C7DB5128275957D6" modified="2022-08-03" version="1">MTATGVQAAASMSSTVVPSKPTASGGSDPTDPAANNTQKPPRQPPPAKPRSQRSIAAEAGEVVGEYVLGETIGEGTFGKVKLGLHLATGEKVAIKILEKKRVVEVADVERVAREIKILKRNRHVNVIQLYEVIDSPERIFLIMEHADSGEMFEYIVARHRIREAEAVLLFQQIVDGLDYLHANEITHRDLKPENLLLQSSASTPTGYIVKIVDFGLSNTHDGGRLLRTACGSPCYAAPEMIQGKLYKGPVADMWSLGVVLFAMVCGFLPFEDSNTNMLYKKILSADYRLPPFLSHAVQDLIRRILETNPEKRFTVEMIRQHPWVAASRATGLTSAPSLSRLATDERVREMILQQLESLGIDSDAVVDALEHKVHNHLTASYYLLYNKLLRIMKDQPASRVPSQQQQYQQRPPSQQHHRGESTDDTRNKREVVPIRTASTSNSNAYAVVLTGQEPTTPRRRSHDLTTLTPRGSFTEALDKRRHTLTEPQSVATPSPAALALRRRVPSSSSPSSPPAVVVQTAPGLKEDDMRTAVEPAPPRILQPHKPTAPPPDKKLQQFTALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL60</accession>
    <name>A0A8K1FL60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL60"/>
    <dbReference type="OrthoDB" id="73076at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="743"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="670"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1187" mass="131115" checksum="6DE8F2B0D02DA3DD" modified="2022-08-03" version="1">MEAGAARDEDAMSAAETTPQTTGETSSPSTSTTHVTSYDSMRTTSDSDRLDPLSGNDGEEAINVIEEGEHVSTEDFGLSSTEISMHAPITMNVNMELNAIQQIDAFLTTPTVVGSSQPESLNEGGRVVDASQATTTATENDKSLPHVVVPSRRDEKIQQIQAHPIVHSISPDGRSIECKCGKSVRLNPPWYIIKFEQHVVSRNCTFLRKKHPPKGHSSTDFSVVPINDSADDVSGPDISTLPTVEESNMTDSVGDDTPYEEPTELSEYGLKSAADLLKLRALLGTNKEDLQASTDMETNEPSLQDQALSTVSSHPHFSRMTPDGRFVECKCSMLMILAIPWNLREFLKHVADKTNPLVLARRKQNKTRVQQRKPRLGDGAAYRVGQRHLVRETRWDPVSANNILPCPGIRDDRVGDFINATSQVTGGSRPRRRIAEELYPQLFESSEEAPPKPTPKLSLEQKITLHDAVESEALWFVDRDANSVRSLDCRGAVTTAKNEQLCVGCRELRANTSLRIAMTLTSQKRKVALDATALKHTMRHTCSLLEQEFNMDEEYARLLRDLFLADVDEGSIKNVWFDMAEMGIDGMFQSHPALLGLLESMMALKDKERRGVGLQNMAYSDQLDAFMKAMSDLSTEACDFFQHHLGGRKQKYLSVKKRKSNDEATGPDVQSSTAQQESASQENGSAEIESIHNGDVSMPLAHSDGFGHLIDVAESAGLHLNVSDIQAVDLATFNPAAVVNTDAATSSEGKSEGLNKNGGPSVTDAVGEGIDREDSSDGFESESNDQESGNDHPSRIPGITAGVIPCQGLREDRVQAYVTNAVQVIGGSRPKYVIAKELFPEIFEGSSTVKMAELLSEDQRLILQDAIFSECLWRVDKVGNCIRSLRCARRVDRKRSNGVCRACLDLRLVANFRSVLCRAKVPKKVENLKYVPTAYTESDPFMRKISKNASLRALFQIVKKSVKEDKKSVVFWLRFAKMGLFGHFRSHPVFEGLIGSMVEMKDKERRGVGRQNMQYAKPLDDFMSVLASLSMDAFELFTVHFCGRTTRSQKVRKRKAIAQLYGPPIQQGLPDGAMSDVVMTGSQLPATTNHPTPMALESGTIVEQQQAVQHIISAEDFLAARALTTADMEESQRFMDRMLDEVRMSVNHQELNTTGMPHEKDTSADETNDHLDPQTYLDENGVLTSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLQ0</accession>
    <name>A0A8K1FLQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">STIL N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005526</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLQ0"/>
    <dbReference type="OrthoDB" id="76173at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031023">
        <property type="term" value="P:microtubule organizing center organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071539">
        <property type="term" value="P:protein localization to centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007224">
        <property type="term" value="P:smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026123">
        <property type="entry name" value="STIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057731">
        <property type="entry name" value="STIL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15128:SF0">
        <property type="entry name" value="SCL-INTERRUPTING LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15128">
        <property type="entry name" value="TAL1 SCL INTERRUPTING LOCUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15253">
        <property type="entry name" value="STIL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STIL N-terminal" evidence="3">
        <location>
            <begin position="267"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="765"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="576"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="773"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="784"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="933" mass="103883" checksum="841898F6C331A0B9" modified="2022-08-03" version="1">MATSSVRPPRAFSRYDAAQSSDRTFTGLAASQAAWQRRSGVASRLPSARRGRSTFFPDSTDDEDGNGRELSVVREEREERTLRRVQTAPVSRGSLGLPVGGEIHFPLTRKVLWDRRVLAGPFVVTTGDVLPRVVITNSVLKEIYALCRDLRRRNGASSSSVSQVSSRRLCFVRGEQTDRELTITRVENDADETQATWRAPVFHSRPRHHEDEERLEEQMINTTKRALETMETTRTNPIEASLVVNAPPLGGGSRAEMEIEMEVALPCAKMQLALIRNLPLLMTPLAMSLSRREFGSARRCGFMTLDRARKAVPLLESDPMARQRPIVGLWVYGVSVEGSVSGDCDTFSPQLRLDHPFLYECCIRYMRSKIVQERVHVAPDTFLLAVYPGQSENQDSDGASGGPLPRFFECTLKRQAQGKDSSGIQWSLGAARGRCLAGISSFQGRLEMQFSISSDVEQASHPSQPAPDIVAVDDTSCRSDELPQQAPPASTRHAERSSLQIDTSHAPRGLAESTPSIAGTLLGSLTDGSTPVPSLSTPTVNSSATPPSPVEAEQHHDPLDRFPAHRGCCRSQQLLALQHQQILENQQQQLRQLQDQICDLQRMLAETRDENARLVVENRRARSLHDSDDRLTTSDLATPTSLRLSTAVEENIKQEFSGNLTATAIEDAFDLAVEDVGENPQHEEVSSNTTEEEEEEEEAEEEEGEKEEKGEKEEENANDVTFPSFQDNDESAVSSLQLSSISQHSEASSLSSVSSSLVGSRLKSFVTRDDTPAPQTVDSQPTGARHESLRTDYRRQTNIHFEAKQEETSREEKQQDTSRETGNNREAIHVVICPHARPYRPGEHCEREQLDDDDDFSRALEPLIGTRLTVPHTPSRDGVVKPSLELGNLTDNNMSLFIPRIKYVVEPNISDSEDDEIQRIELKYKRHSMPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLS4</accession>
    <name>A0A8K1FLS4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLS4"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF148">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="377"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="533" mass="60588" checksum="2D191ADA4A9C9473" modified="2022-08-03" version="1">MLLRRLVCCVLAAHVLPRNGRMMRHANDQLDAVVPPFQMMITRADASEVLATRFASEEAPLYPEYDENYDVELDLDLPSKRKLHRQRGSRHLDSDPIEIGITPTLDGETPPRRPGMTQDWSQKVKPATFNYGRGVGYVTTQAVESGDVLFSIPFTEIMTTETAHQGRIKVLLDANPTLPSSIALALHLLEEKFRGEASRFEHYIESLPSIAGLNGTIFYSDKDFEGFEASHLYRVTQGRRQAIKNFYEALLGPVTSTAVDPPLFTSDQFTLDNFRWAMGIVWSRAFPLSKSDEDAVIAPVLDTIGACVEADCPETRLEWDTRSQRLVVFATEDYAADDEVRLDFSYKSSALMMLNHGFSRPAPWSQVETFDMSIFLDPNDTLISIKSHLLQTQNLTMNGTYILRYNSNSLDAEMMKSLKTKLLSAAELDKHRELFEPTSDRPILSLRNEFVFTRAVLLSCRNLLKQYPTRLEDDRQQLTALENQFGGRVPTDRRIHMLRSLVIEKEILQHTEQLVLKQWQDLLTLDNPNVLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLV6</accession>
    <name>A0A8K1FLV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006138</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLV6"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="91" mass="11043" checksum="55B997C51959EB0D" modified="2022-08-03" version="1">MSQREFERKMEEHIEEMRVAQTIAYFSRTVELCFNECVHSFRSKKMDDKELSCVNSCAEKFLRHTMRSSVRLQESYAEIMQQQEQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM06</accession>
    <name>A0A8K1FM06_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM06"/>
    <dbReference type="OrthoDB" id="57939at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="2">
        <location>
            <begin position="43"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="1">
        <location>
            <begin position="263"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50290" checksum="FFD3919EFB1241DE" modified="2022-08-03" version="1">MSAAAAALMKKVDTLGKRKKSVDAEDVKTIEKKDEFNPNMYYVSLTSHAEQFGVEPVRIRWGQREPEVRGPIIGTNRHHKYRNAIGAHGGSYCIYRGLAIASGALDKSSLPNLAQTTPAAKIGPHPSWGDPDKIVTIDPFGHCVLEAFPEHFEKGYDIRPTIAVTKAHMDLPEIHEAMRLGRLKGDGKILKETGQIVITKAAIDPVWHLPAVAKRFNTTEANLRQMIFQETNGMYPELVTRTDLKVFLPPIGGISIYIFGKVEDISDPTKTLAVRVHDECNGSDVFGSDICTCRPYLTHAIEVCVETAQKGGAGVIVYFRKEGRALGEVTKYLVYNLRKRQEGGDRAEEYFNCTQAVAGIQDVRFQALMPDALHWLGITKIDKFVSMSDMKYDAIVNSGIKIIERIPIPEELVPHDAKVEITAKVFAGYNGGSVYKVDEETLKTVTGRGDDAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNF2</accession>
    <name>A0A8K1FNF2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNF2"/>
    <dbReference type="OrthoDB" id="166524at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="40486" checksum="3B8D58B2FB5DC2DE" modified="2022-08-03" version="1">MVEDSLALRNRVSWDETSENPSSSESSEPVEPRVARSRKQESTEADKKKRTKKKPTYLVRKEEVDLLREEARTLQETVTRLRIERGLPTEREMRSLELAQNENDILREKIRKKSLSTGRLRSLVTKHTNHLRPRPMETFIHLGCDLAARRATLVSLRETIFQHGQEYLQERFRHQDEQAEYQVTERYEDPEGNRHSDISDIVHFEGVQSVKQVYDALVYYLSNMELTVSEQLGNLTLREDIDAIDTRISNHRFVSRSDHGIATETNTVFCTQYWENHEQHDVVATLSLRSFHTEDDLVVVMKRCASLTLHQPRFKVDRVALKDMHEKMGNWGVVMVNSLRGALYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNI0</accession>
    <name>A0A8K1FNI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNI0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="367" mass="40812" checksum="180C2847CA587C6E" modified="2022-08-03" version="1">MVDVMGASSGENSVARAPITGTGVDASMEPMVEPYDQHRSIDLRSECYRRGVRPVRSGPRANDNKAGYIALLREYDRTHAKPEGPTANGNEKNESHSYRFQGKHRLQPHPLLQPQPLQPQAIMPVQVSAGNESSGTATTASLVSASQQTHTTMPVVIPPPTTSTPIDSMHQGIVYSGATGPQKRQKLKNGHHTQGKSSEEPQENEHVPPKRPQPVKMIMPASVTAVADNPVQPPAVAGISASPTPLMFTPMSHPTQSGIVRVLTPTEPLQSAQHELTVKEDYIRLKMQIMLERRDYERQVRREDQRFKLHSQLHGVISTLAQLRRLAKEYTVEQENVLLVEVNEDIAYFQGQKRKLKMELELLDRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPD3</accession>
    <name>A0A8K1FPD3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPD3"/>
    <dbReference type="OrthoDB" id="162303at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="28895" checksum="F4830D8BCC89BFC1" modified="2022-08-03" version="1">MFLFPRKTLLRYESRGVRRQRVASLQSLFTIIFQLLETYRDDYFLARNRSSHGCQMLSVIESFLGLTPEVSKLLHDGDVNRPLRLNLNGWRSDQKNLGACPFWTTYRTLKAFPFPRKTMFPCELRSVRRQRCVLLHSLFTTLFQLLEEFPDDCFQQSDECHALKSIEEFLGLNEDVQKKLRDEADGPPGRLNLRGWQSDRKNLYFQDEVRPSLLPSDDEEDEEGFDDHDVMLVPMNCYRRRCPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPX5</accession>
    <name>A0A8K1FPX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPX5"/>
    <dbReference type="OrthoDB" id="69269at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="2">
        <location>
            <begin position="894"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="837"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="871"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1176" mass="134030" checksum="95CD34D741E3EE2E" modified="2022-08-03" version="1">MYHIAEVVRDAKRDMEERYEGGRLSTWAFFTPFPFLYALSGQITQTMQRKAPDLVKRAAVRTRDQIAGAVTTSQQTLHEWRVVTTRRGQFLFYTVKTTVETVELPGAIAPIRSHVAVPLLNGVEGMVQFVTSEELPELYFVAKNSMTSHVVLRHLVIPPLSAMEGLVRYMVILPSQLVFPSREEIEDRTDVFLHVSTSRLQSLVEYLYSATETLDQHWSMVQWNILGRGPYESLSMDRRRDVIHSVHQRMRIISSRYKLYEFVATIKMQNEMLFCDLLKEFPDCGGVPLLQHEVNANEELRSALDELDEDSFPCWFYRKIEIFMPSTGSENGDTASTVDGTEPTVSSGKTKWIEFPAHENRRLERRYRFYQRQKMLGRCPLPSPIVVVDEGRHEVNMETMEMTPVYWEPVEKIQVRRSIWLYAQRNYGLAPYNPSAELVLEQAFTYYLAFFNEEINKKRSLLSRTRHRRWMQIDNGSTTSTTPTSAALRYNSGGVCSLSVPVEGHLVELKGPHDITQYKRLLAGTTPFTSKRRVYRGDPRIRADPKLLEQWKKSMVVEGDPSEVPPNEDDADIEEEIDHLVLIVHGIGDALKTIDIINVVTLRSIIDCATSLRDLHREALRSTHFDGLGDKHPRTEFLPIEWHTKLHIEGLDSAIRDVTLPAIPKLREFANDTVLDVLFFMSPMFHRVILDHVANEMNRVYRLFQARHKGWADDHQPIWKKKKVSIVAHSLGSIICFDVLNHQGPKQQRPAECPSSGDRDTESSDESHGEHFINGGMHDDASGFEALMAASLRERSRSDSECISKFASTPRRRDRMRHHQMNGLPTIEPAPTVVVHTKKSLQHRRAVAGTRRRKRRSHTTKNYKSPRHPRSSASTPKGSSSTPRNATDHGVPELAFEVDNLFCFGSPVGLFLNVRGQTIDLDFHLPTCKRVFNIYHPYDPVAYRIEPILNPQRANSKAAIIRTFEGRLRFQYQLRNSFRRMWQKLRQWRRNFETQVESAVHSVGLVESMTWSSSTPSSTDVHALGDAAAAAGNGNGSDEDPVEDETVFGRLCQGLPIDYSLQENEIEITNEYLFALTSHVIYWNNRDASLFLAQKMILEPPHESKEVGDVESDVANHEVAEQEEVDEDDDDDIASGTITPAFSPFGLEDSDEKEVEEKSSGGLSAFFGLGGKVRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRC4</accession>
    <name>A0A8K1FRC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRC4"/>
    <dbReference type="OrthoDB" id="6153129at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33206:SF1">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33206">
        <property type="entry name" value="PROTEIN CBG10425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="73706" checksum="313DDBE93007046D" modified="2022-08-03" version="1">MKGYELDALKRLNIPLLRWGKGGKNDYRVKVKNDIGRFIFITNISRPKYQAMLSKTYKVKLDRIKKHVVPNYKPSGSYEYIGGKLTESHTWYDISQTEFEIKAYQILSEPKKAFKVNIQLGYVLIDRTSDIEQNNKFYPLLEAIVKQEVEEAKAKARKNMPIKAFKRSRLARANGDKLGELIKNDDETSEEFNERKKLLKQAYSIYHKMKANIAGGPSIIFNRFAKACETTIRGGQDMPCGALNLQIEGRCSNSGSGVGAVFMNTDNWNNAYIWHTDEEPVEGGLTKVKSYRGKSGFIEAVLNDKLFGFAEVDIETPEHLKEYFSEMCPIFKNIEIDPNNREIIGDHMYDYNQEKFAKAKDGYYEMKEEDKIKGTETYQVMKAILDEIIDAYELPKKNNNVFALSEIDMLKKASGSKKLIGDMMKLVGNSAFGHSGMDVSKHREVKFSHNEVQVRQLIEKPQFVDLEEYGDSSEVLMKKRTTKLTNPIHVSIAIYQLAKLRMLQFYYDCIDYYFDRSDFQNQEMDTDSAYIAFSDPEAFKNLFKTPELKAHFEEHKMSGFLVPIRRKTIYMTKRLLNYICYLSDETGKLKVSAKGVQQGGGKNMDILTPGAFENVVKNKVSFKATNTGFRIDKVHKRIVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRI9</accession>
    <name>A0A8K1FRI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001202</name>
        <name evidence="9" type="ORF">Poli38472_001203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRI9"/>
    <dbReference type="OrthoDB" id="67021at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="514"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="546" mass="58537" checksum="EDC18184E6CF7571" modified="2022-08-03" version="1">MALSLGLSAATHGMRMLADNVCSTGVFSCSYGLSTFESSGKYPKAFSQDTCANYDGRYVDTDGSYGLLVVTAIFAAAMAFSIGGNDGANAWATTIHSFAIKFRPAVILAAVFEALGATTIGYGVSGSIQKGITNLTNPECFACGFCNSSMSLYYIGMMASLISASMFLIAATWLKMPVSTTHAIVSSVFGMTIVFHGFGCIKMGWDNLGGVIASWFISPVLSGVMAVIIYYIVQFSIFRASNPRTRAYYVVPLLYLVVVFVIVFMINVKAPKLKSNPRWYGVIAGLVAGALAAGIYVIFVFPRLKKNLPSLSEANRIGLFRVRNSEAEMAGKEEEADADFKGAETPKKLGLLDGAVARPSLALQEEYEALSPEQQDAMYLFKYLLVMVACLQSFSHGSNDTANATAALAAVVNGFKHGLDDCASPESPWWIMLLGGVFLGLGIWFIGHRVMDTIGKNICIVSFDRAFCTEFASACTVVLATLLNIPVSTTHCQVGAVIFISMAAKESGTIQWKLVFTILFSWIATLPFTAGLAALVAYILSFAMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2D2</accession>
    <name>A0A8K1C2D2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2D2"/>
    <dbReference type="OrthoDB" id="200773at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="802" mass="88005" checksum="4537F532B5F59C9B" modified="2022-08-03" version="1">MPPPSLRVLTRAATFSQGRASSKEPMPSAKEDPHEDGGLSSVPEPHEDDESGSSDEEEDAIAVTPVTTAVQAANETKATIEKGDKTITRTVSAPVMKQDVASNEIRPRKVSVAALIRSFSPKGSRKATTANAPATTTPTEPAKHTKTTFGSLKRSSLSKSPVTETKSTDQSKPADNTDQTVQEQARRRSGLPPSPSSVSKWKQVVHRVAKDAERLKIKVPPQLQLATVDHKDGDQERSYAVSEDTGRGFVDEVRSTLNRLVELLDSIDARKLSAIRLGGELRGLLGKAQDEFSAYEDAFLEHATKVGVAIALQNFASSLHQVFPIVERLQTTKFLLNRTFKREVTFAFQEINSYYTSLFMELSMSVAKNAGLVLPLPSPIKPTPIAEEREPEPQLPPPPPLTIEDPPKAPTGDNICLEAHQYFFGHGRQVDLSRAHDLYKVDKAPHQKTGAQTQEFLRQARAHFTQAASNGHREAQFRVAQLLESGIDGVESPDVLQATHWYRRAAEQNYPKAEAALGRILFDEPHFHDEKGPNGRMSSRPTRDVAQAVHFLQRAAGKNDPDALTLLGVIYSRDQDVKSDVDRAIAFLRRAVAAGNHHAMYHLAKVLLTSCHETFSSSSSVPLRNQEDLHDEAFTLLLNAAHNGGITDAFFELGEILDKSKFLRDPQAALRHFVKAATAKQPHIVASKRAAAMFYAGRGCSVDRWKAHHYYSIASEAGDDEALNALGLMYEEGDGCDLDFRKAAECFRKAAAQQNAHAHFNLGCLLSHGKGVARNLVSAQAHFQKAFQLGYTLAQDFLQPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2G6</accession>
    <name>A0A8K1C2G6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2G6"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43328" checksum="9DC2FEFCE4DC9873" modified="2022-08-03" version="1">MTPTQTQDNRRVLIIGGGIGGLCLAQGLKRQGIPSTVFERDPSVTSRSQGYRLRINNDGFDALEAYLSPKILDVFKASSAEFIPGFQFFDPKTGEPSATPPPSADDKRPSGPPPSGDVTRVFSADRVVLRSVLLLGLDSNELRYDMAFESYTILENGLVEAVFENGERVTGSLLVGADGTFSRTPLTPELEIALHPALHRGTSLITSREPHVSLFMEPMRFTKGNPQDISPELPDTKDYVYWVLISRSHNFHVAGYSSDEELLALNPAQAAELAQEMTKDWDARIRALFHCDHVGDSCGYVRVSTMPPDIGDWDAPCVTVMGDAIHAMTAAGVGANAALMDARVLLKSIQTYGVADEAVAAYEAEMRLYARKLVAMTAGAGKKMNDQPDFEDMKPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2R1</accession>
    <name>A0A8K1C2R1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013246</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2R1"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035432107" description="Endothelin-converting enzyme 1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="37"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="473"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="75177" checksum="E5ED6953475B7735" modified="2022-08-03" version="1">MKIFVSSALALAAFAANQAEASYPDEVAKMLDTSANPCDDFFQYTCGGWIKNFTIPSDRQHYSYSFNGIGDRNDAVIQEILKEDWPLIGELWDSCNDLDANTAKGAELLQKDLARIAAVSNKKDLFTVGGDLSSIGPNFFGGVGVSADAKDATKNALYTGAGSIVLPDKSYYTDNSTFADLEADYRKYITTVLTLAGVNSSGGQQGQQGGAANTKFAEDAIINIEKKLAAILPTDEEESDPEKTYNPIKYSEAAAKWPLSFGAIANGLRLLELSSLTESSNVIFGTPAYYDRAEKLIESLDIKDLKVYFSFLYINTYVTYLGQPFLDAQFELFSKKLSGASAIPPRARTCTSAQISFFPDLIGKYYFLKMFDVAREENVKLMVKSLESAMEDHIAKLDWLDDQTRGKAKDKLQKITDLIGHSTQKKSYPFSLERDNYLGNVWAIKNSNWAESLKKIGQPVDRTEWGMSAATVNAYYSPTENQIVFPAAILQPPFYNGGSHPVQNFGAIGAVIGHELTHGFDNSGRHYDGDGNQKEWWTEATAKEFETRAQCMKDQYSSFSAYGDSGKPVGNVNGNLTIGENIADNGGVSLAFDAYHAWAKSGASFDAHGVKDDEVDKLFFISNGQVWCNAIRDGYAKQLLLTDVHAPKRWRVNGVAMNSPEFAKTFNCPAGSKMNPEKKCKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C357</accession>
    <name>A0A8K1C357_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_010475</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C357"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="12">
        <location>
            <begin position="519"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="169"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="306"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="414"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="678"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="755"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="814"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1043"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1245" mass="142975" checksum="7CEFB3FBEC9FCA1F" modified="2022-08-03" version="1">MGRIVRLELENFKSYGGEHVIGPFKRFTAVIGPNGSGKSNLMDAISFVLGVHSRQLRSNQLKDLIHKGPGVSDTTSAYVTLVYELDADEIPGATQHQELLFTRLISDKGVGSYRVNHEDVTFDAYQNQLKEIGILVKARNFLVFQGDVESIASKSPEELTKLFEQISTSDDLRLEYERLLEEKNAAEENTIFAYQKKKGLVAEKKMVKEQKDEAERYDTKHKALNQLRIEHFLWQLYQVEEEVRSHEEGLKACQEELSLFLAKEESLTTTYREKKKEHTAGLREAKKSRDRVHELQQQIDEIEPQTIRLREQAKHAKKKLDEAIETEKRMKMKLGSKKYEIEGLRKDLKDLSAAKADLELKFQNRSQDEEELVMEGERLEEYHRIKEAVQMKTNLLRNELDSILRQQSADKNKVQTLTQEREENEKVVELLTEDLHDAENRVHKMKDVIAQTEQAIADTERSLQEAELEIQNQASRKQQIQEELERVNTKLRDLRDDRRQSQVESKKAETIETLKRLFPGVRGRLVDLCKPVQRKYNMAITVATGKHMDAIVVNDYKTGQDCIQYLRDSRSGSAQFIPLDKIRIKPINERFRNLGNNIKLVIDVIECDQDIEPAVMYAVGDTVVCDSIDVARDLCFRQNEKVKAVTLGGMVVSKSGSMTGGRTQSDVQRAGRWDEKEIDSLQQKKDDLHEELHSLEKHGASYSKLQALRTQAEGMQNRLRYAKADLVTTESKKPKIQTRIQEAEQRIQSAILPDLKKFEAAVDSRKAQVDELQEQIYSVEDELFADFSEQMGVPSIRVYEEKVIKRQQQHMDTKRRITEHMTKLEAQIAYLESQDYEGPMHAARERADIERSQLKHLSKEDGQMQKKITTLVQQKKEAEALCADLTKKVDDIEEELKIIGKKKAKSEKNKGEILKRVTGEETSLDRLKDKKVEILKRATLDQVQLPVVDKDSSALDGDTDGQMDDVSRRISVGSSGVSRMSLANSEGGLENQALQRYAVQQIDYSSLHDHLVIDDDQEYEEVNTTYEQRISDMVSELERMQPNMRALDKYDEIQGRITKEEEELEDIKRKSFEAASNFEKVKNARYERFMEAFNHISGVIDTTYKQLTRSSKHPLGGTAYLSLENTEEPYLNGMKYNAMPPMKRFREMEQLSGGEKTVAALALLFAIHNYRPSPFFVLDEVDAALDNVNVNKVSTYIANCDFQCVVISLKDNFYEKADALVGICKDINQQRSQSLTLDLTKYDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3R6</accession>
    <name>A0A8K1C3R6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3R6"/>
    <dbReference type="OrthoDB" id="65217at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="32873" checksum="7D1AD0C7A9A2B055" modified="2022-08-03" version="1">MLDLKPLKPHVEAAIEALLRAADARVSWKQPSVNGDEGDPTTEIPRVPYAFLPGVYKSATPSSESTTHNSSSEAMLPSQTMEAESEHGAIQLLLHGDNTFEYTWTMKRRAPRAMEYTVEMRGQWSKPVLNRSRRGDEDQRVFLTTSRIRFQRLSNFDSENQIWKLSLRTLTRHDSDWAPVGESERGIPPIVIVFECSDGLLTSTGAVACAQVLTNSPSCRVLAGLTKKIANKLGGPLDVMTEKWLPPRGVQLRVSVDGQLAVKLFNPFYWYDNVIVMIWNQWESNCVVHDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4D9</accession>
    <name>A0A8K1C4D9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4D9"/>
    <dbReference type="OrthoDB" id="1687175at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710:SF2">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="446"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="555" mass="62010" checksum="891F739272C04C2F" modified="2022-08-03" version="1">MNAKRKRHIGQSVVHPSSLQMGKVNSHGSSAATNTPRSNGEQRRSQHNDQETSKTLDGFMMLDCCHVEFPDELTQAVLSGQEIKHVVAEDLLFFTNLVRLDMSDNEAPFEPFACLPQLQELDFQCNALQTLSVDNGFQMLEVLNLSFNCLTAKDVEELSKLLRIRELYLSNNWIRSLPPVMDRFSKLEALSLEHNNIGGNEIFNFLAMAPRLRNLNLSHNKLTMFPETALTLEEKRGAGFYNLLYLNLAHNKITDEEDVIYTAELHSLRKLVLYGNPFTHAAVSSHDPSKLNYEPVTLLKAHIEQLEREIMVVVAYPETKKSRPGATSYENVEIYKMLPNEVPLPSPFRSRATSFLLPEESEKKMKPEAQTTPAPRVVRLAVDTSDSTFLTGVGLEDLMGDPSSTELPAVPASLLTRSLAVPKLTNPLKARAALNALRYQLGHPLTAHDDSDLVPTCSQRPTQSHLHRQLPRQLGAPDRLNSQDSSASWSRPAFTNYPAPYRPAQPTRAIDDALTQLSHSIAQKQRNSGAPQNVDHALDSLVSTAQRVNLTFNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4W5</accession>
    <name>A0A8K1C4W5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006496</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4W5"/>
    <dbReference type="OrthoDB" id="6608471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="36558" checksum="D993ED3A4B43A1EA" modified="2022-08-03" version="1">MASSDVPPFSIDEPRYDQSTYYGRWRQFVELVSPSALLLTQEDINGVRKTLEDYRQGHIKRGDKSDEELWEARRLYESVVHPQTGEVIPAIFRLSAFVPVNIPICAGMLLAPPTLFNTVFWQWVNQSYNAGFNYANRNASSEQDTSDIFKSYATASFVSCATAVGLGKIVETAKSLSPGMRSALRKTVPFIAVASAGAFNAVSMRFNEFVEGIDILDEEGEVRGRSVAAGRQSLGQVALTRVALPMPILLLPPYIIEGLNKARLMPKTKYPRLITEITVVTLCLWGALPAAVALFPQKGSISADKVEDAFKNLTDRQGKRIEHFTYNKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C504</accession>
    <name>A0A8K1C504_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_006555</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C504"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17941">
        <property type="entry name" value="DEADc_DDX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="80"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="280"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="645"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="677"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="725"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW56545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="767" mass="86912" checksum="4B14D5F2A87F87F3" modified="2022-08-03" version="1">MSTSPVDAVSAPAHPSLKLYERERLEVEKLEAQIKEQTPARGSQLGEADSFGAFPLSDATKRGLTKCGFTKPTRIQIGTIPHALAGRDILAAAKTGSGKTLAFLIPMLEKLYRLRWDVEDGLGALIISPTRELALQIFEVLRSVGKTHTFSAGLVIGGKNFKEEQYRLIRMNILVCTPGRLLQHMEQTPDFDAANLQLLVLDEADRILDMGFREQLTSIVSYLPRERQTMLFSATQTKSVKDLAKLSLKEPEYIAVHEKSTQATPSGLQQSYIVCPLEQKLDVLFSFLRSHLKQKIIVFLATCRQVRYIYSLFCKLQPGIPLCSLHGKYKQGKRVEVYYEFLNKPACVLFATDIAARGLDFPNVDWVVQLDCPEDTANYIHRVGRTARYNKQGKALMCLLPSESEAMKKHLDDSKIPIKEIKLNPAKTQSCRQKVASVVAADKDIKALAQKAFMSYVRSVFLMPLKDVFDASQLPLEEYAVSLGLPGAPRMPFLEKLKTQDVDHEKLRDELRSKKNVNRKLAQLKEKIKAEKAKKKLDRELAAMKADKAAAIKKKQEEEEENESEEEDDLMVVKQHHAWDKEDDEEMLDYDEELRKKKEKKQQKKLKIRMDNEVNKSKVVFDEEGNSMNVLERMGVQHVEEDEFANVEAKAKQHAAEVAARLKARDAEDRRLEKERVRAKHTKKRQKLKGERAGDEDEDDEGVQLATGSDDDEEMESASESGSDNSDDGDDDSDDEDDEPATKRRKVNRAAVESQEELALRLLQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C509</accession>
    <name>A0A8K1C509_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C509"/>
    <dbReference type="OrthoDB" id="69638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="103"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="725"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="808"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="961" mass="106639" checksum="1F7552BDA5A7DC6E" modified="2022-08-03" version="1">MEHDEPIADHAVNEDVHEENPKVVETEKTVEPASTPDDGARGVEIVCSTPLLTEDVLERSKNRSTSTASSPTKEHEVNTLEAILAMSEMRREDEIPQYEPLRGQWHYGQAVFARHKKTPYYYSGNIATYLGAGLFMIIFDDGSLNYRVKREDIVLRPTPKRPRSPLRGDAGARDPRENAEGDEDGDEDDDEIGEVLGERSTWYRTNVHLGDKPLMVDFSVSPPRQVSHGRAGYDLIDEAMLDMKQLECGVAYEDDSTQVSDSDESSEEDMTMTPWQQMTQTFGMGGRHAKQRASRRSSISSLSQIERLSMNSKSMNNILASPKSIRQIIQDYLAKKTKKVQPSTTGMDPLCEIICKMEIRCTEMRARPERTLTMRSIIINDSQSDSGASRRNAASPSNASSNNGSPRKHSAPVASMTSLGAINPTRVVFQREQDGTRAYGTIRTKLPSGEYEVVAEGDQTITVQVLPQKDLDFLPSIKELQAQIQDLQQQSKRLYAGRKVQVNLYPGTRFSGPGVITLEDDSNPGMFHVLLHNRIRLVNVPAEKLVPLKEKKREVVCITDDQFLVCSGKHKVHIGDQVFVRCQSELEGGVMEEKLGVLNGVYSNKTAAIDFADGSTGYEIPPQLIMKRKRLPMGEDIDVLSLKNAVLMQAASSPDGYNVDVGYQVKADHPRRASVESCVVIRKHPSSACDLRFPDGTISFNVFPSQMILDQLPVDATQDKAAVSYDATPGEYILAWSSRFGRYCSANVANKTGEGASALYTLVFDYGEQKEQVPSEKIVRIDEPDAISPTQKLTNYSIDTIGFEILPETFTVGEAVLARVRGTTQYFNGTIELVREKERTCIVVFDSAERDEHVKFSSMFSVDSRHRFKSLGQPSGSSSNGTAAQLQPELSALGPDMLGRGRRRHSASSVGSVLMSVAGSFFRARKLAERTERRGSHLVTEMGANIRPAMDEQERPADEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Q9</accession>
    <name>A0A8K1C5Q9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-galactose transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Q9"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47079" checksum="85ABAC6B8A4494D3" modified="2022-08-03" version="1">MAEPLMTRCHRFFTPLVVKKLVLLGLLSVQIGFQPLLMGWYAREARNVGLRVGVIEMMKLVMGLLPLVLTGQLVSEVKDWSLHTALQTTAAPALIYVLQNYLNQAAVVVLDGVTFNILNQTKIIWTALLVYLMLRRYQSRPQIVALTILCAAAVLMTTDKAKSKTPESHRVVVDEAAADAAFFTGAYQALIAAILSALAGTIIQRALQSQKRNAYLVTVELSILGELTILAWTMTTSNNGFFSKPNATPGHPTGTEVSTDSMDEHGLWYGWTFGTVFALFCQAAGGVLVGFVIKHCGNVEKSFAVVFGMIITALLETHYNDKPFGMRGLIAIVMVAVATVMYTMYPPPQTKEASSSQKVTSAPQKRSKKSSAVAIELEPFLAPSSPNLEGAMDSLVMKQLPQDTSSEARRLTRTACSSTNSSSDRIKDVAIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5T0</accession>
    <name>A0A8K1C5T0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="841"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="919"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="587"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="972"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1621"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2177"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2292"/>
            <end position="2433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="374"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1653"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2343"/>
            <end position="2354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2366"/>
            <end position="2377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2433" mass="270209" checksum="3B25B2698A3275FE" modified="2022-08-03" version="1">MMTAESTRKEANERPKWEVYSDEYGNFYFYNTLTGESTWELPTEEENVTVDEAETSVGAVLDEDTAIRPVEGVVERAKASYTDYDIAAGVIDTMLTLVRRVEETAKQQSDAAIKPKKKRFVSPAAEVRYKKNQAKHEKTQKREHLLAMTRYMNLLAPPVTSDPTDAKPRQVGALFSKEDAFRWRLEKEVEQIRQRYQTRQKREKHHKQVYARVSQGKFLHVLRTELLKHLLAQITCSSELQQQRILLLSSPQYTAELEIKRKQQMEPEILERYEQEQTQALEASIKNIRRVFLLVDDAGVGSVHLLQILFAMVSEEGIRKYATQVHGLQTLIESIDIQRFILDFTSKQRTDECMLTPKDFQAFAGLVEDVVTHFASVKEAVNEAEDEIAGAIEASSAVGGSFMRTRLDMASKKKLAQELASLKATHDEMVANQRNQILSAFYGEGPSLLASKEEWEKHHQHRYIQHEAWLPMYCCLCRRRKWELWRRQLEEHEADHRSTWGSQRILKLKSEQLRVANQEDDTAITQPERLKPASAVATISEDCEAPLLEDEALLTEFTKTQAISEDDMVVAEVLKTIVILIDQMHEHQQPVSPPPRVHVRSAKQIQTSVSRKKKRKKSKKDLADEMDQVQRLMTIFDNEERERKTMHTEDVQMCILLERDRRSTEKPLLQIQDMAHNAYIKTLSHCVNPFPSLFRLQFERCLSFEPPQRLVLLVTDGGVCEPDMSAPSRYYILRTVPCRTEQEGAFVFNSNRLVQDKRVTQKELFQAASQNDFAAVRDYLQVLLDENADGDSKGMVKYLLEPKTRNTLLHYACDNGNLDACKYLLMCEGMVEASLNEPNVFGHTPLFYAASSGKLPLVKWLISNGADIDMDYSDHEDIQPRDDDHGMFTPLQIACFKGYEDIVNFFVECNAALSGTRRNGKTPLHVASSQNHKAIVKILMEAGADIHACDDQGKTPVDVAHSSLLSVLIPGEHGVAGDDEDADDGIEKNRDDDDDDDSFASSSEHSAAIEIVRSAFGRQIAREFHNKSWKSRMNAINDASIFVQNGSNGKNVTKLFDASCQMIILALQDAVSQVASSCCTALLKTAFTAVMGIADFHSARFHQDRPAINRIAELLLVRGAGSNEKEASEAVASLLFLICKSADITRHLTSHIFQIMGPAGSISTVALSPSKSIDVSSSSGSLSWRLQLVAIKILNTIASQYRLDQGVGGLSFQDGVKISTTSLENASVHVRTAAIDLFVQCLLIRCEQSDMSGTVDDIYEQIKNWSEAIFKQQNQTLKPSVQAKINNGLKNALQKSKRLHLAGAGEQGSEPKEPKANICMLDFTGAKPASPRSKVGAQKEDDLPYAEPIQDQYKEEAASVQACFGEKVTRCLFSNAWAPRVEALCFVQFQVESKCLTFDSKPMPQQLLQAIQKTLLLALQDRVNHVYEAGVALLGEVAIAVNNAVSIPSERSHFQDLVRPLIPRLLTRLGDSKARLHVTTEDALLLLSRQTNSLGPEYILEEMIGCDRNASPQSLSPTYLTNKLSVISKLLLEFGVKEASDGNGNLSIKHILQPALQVFEHRDPNVRQVALQIIADTLQATRVATMPFLDALARASRQKIISKLVEKGVLEADMLMDEIDDFDISPPETSRPGTSGGIRPLTASGSSTKHRPALSNPSLSASLSGSTGSSANSAQGPALPYGTALTSDQKVIYAPIIQCFSEELVRCLVDKVWAQREAAVREIERLIVCTANGKLPADNAVPKTIETLRILSQIVEMGLNDTVARVFQCTLRLCQLIATDFVPLVGSGDSSMNEFLESTVQAALQKFGDTKQRLRADCFTLLHSLSSLNHVGQARMCRILNTKYEQLVETSATAAASPLIGVELFKLYAVLLRDGYTAPTLASRPAVAPIMSSLLPAFENKHVDVRNAAIDTYITIYELTNGGADAKDVDLQGFITQVKPAIREVITRKVVQISKSLPKCGTEDIDTARGGESARQQPLALDINKLKHICSSEITDLLTSALPVQRCSGVDKLLQSFTEAPRNPHFKGAWEISCLLAKQLLLDGTSTVCLAAFELLRALVDPAVPSAEYAIPWNEWGVQLILSSTIRSVIQQSANTCVRVRVQVKSLLQLVTTKSNIGKNAVCNAILSAPEQKDLSNEPVKRLRKIALCRLRWQMTMRLELVYEIMSESANNASIAQSSGAAPLNRRKSSSSGSKAGDSLNIENVVPFLGSCVIHPSALVRSAARKIMSILKTTRLEELTKFVQDECSPSLQRRLQTLLSDDEDEDNNYADHFSAEDTTVVRGSRASHVRRVAALRPPRSVPTEEKSMAVDVFPPPHSAPGKSRRSLHTEESSPDFGDYVVQSRDESRQTKDKASTPQVPIWLDQSSSRKSSNSSYSDPHHSKYNQYDSPESMGMAVGGGAANLVKVRRKSSMRSNNGEDDDGCASNPRKAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6K2</accession>
    <name>A0A8K1C6K2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phospholipase A-2-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6K2"/>
    <dbReference type="OrthoDB" id="10265988at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="109"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="6">
        <location>
            <begin position="381"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="7">
        <location>
            <begin position="496"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="775" mass="84143" checksum="91272BD0B79695EC" modified="2022-08-03" version="1">MTTTDALYRLQSELQQHEGAVRSICVLDNDVVVTGAMDTTVLSWIRDPSDNSYGLLPTATIYGHEHWVTALAKLPPNVLATCPSGGFVTGCMDKAVRVYDLEGNLISILRGHEGGVISLGFTADYKYLLSGSWDGTARVWDLATMQCVHVLEGHENGVCVLGLPNGVVVTGSTGRQEGNTVVDFQLRFWTNFTLTNTRRDHTGPIRQLALLPDVGFVSCSNDGSVRVRTLDGEVVAAMQHPLNAEGKPGFILGVAVLSDNRIVSASEDCTARVWGPDGSLLQTIEHPGGLWCVTATPNGGFITGCDDKTARVFTSDPALASATAQATFEAAVEEARLVRARGPSGVEVAKLPDYDQRINVVGKSDGQIQMFRKGTSAWACQWSGPSKTWVDIGEVTGTGSGGVVDGKAYDMVIPVELDQPGGAGVRHLEIGYNQGDNPFQAAQEFIDKHMLDQNYLREIADYITQRSSDYRPPVIEGAEDMVDIPAESSPTGPTYKFFPVRSYSTFETIKIAKLMSTVRQFNDQVPETDKLSEQELNELDQIAKTVQDTQFYHSSTFTVRQVEALKSVTARWATDHVFPVLDLLRLVLVHPQGPPALGNVALEKIVTRALHLGVDPSTSVPNATRMLSLRVLANLFYHKEGRAAILSKKDEILSHIMTFSIYYQKTIALSLATLVLNISRLSVETPEQFTSEDLVTIGSSAMELLNGAPSLEDIGEDTVLRSLVAVGSVTFHADQDVKNAMAALLTVFFAAKAHEIKSPSLQECVEELKQCVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C851</accession>
    <name>A0A8K1C851_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C851"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF5">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="155"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="515"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="830"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="779"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="832"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="854" mass="98124" checksum="7718D23B8FCF4E8A" modified="2022-08-03" version="1">MACFWKLLQPAKTESSSTTDAIQAYVSHFYDVLQLLQGQGIETKSIEQNIFAALLVLIGSIALATVFGHVAMLVSNFNANTTSYQRKMESTFATMNKLQLPAPLRERIRQYYEHLWREYESLDGEIVRFSKELSHTLELEVVLFKYMDLVMHVPFWGDASPDFQKQLMLHLDVRVYLPDDFIIRRGEVGDEFYMINRGIFMVVTCSFHVIYFPLRAAFFPDRHESVSARRLGIVVECLFLLDFLWMFNTAFLDKHGQLVTSRHAIYKRYLRSWLIPDLLASIPVDIVLEIEHQQQIPQRWEMLDELIQIQRLVHMCRAARFTWIHRLHNGHLGRFSRFVFSRYTHLARILSIVIGIIFFTHCIACGWKLLDDAPSSHIQHLGSAYASSFYIALQLLQGQGVPTRSIHQNVFAALLVLIGSIALATVFGHVAMLVSNFNANTTSYQRKMESTFATMNKLQLPAPLRERIRQYYEHLWREYESLDGEIVRFSKELSHTLELEVVLFKYMDLVMHVPFWGDASPDFQKQLMLRLDVRVYLPDDFIIRRGEVGDEFYMINRGICELELGPDSLESTIEPLGDDTNAESTSQAKRSTWSSGRFLVGNGEKKSKDSSLRLQVLRHGQTVGELALLMNYERSVNARAITHVELCVLKRSSFQLVLVQHPSDRHRVITHLLTHVMQTDSQNDVVEALKTEVAAVFQCEEQRDNELLSGTHAALLLSNAINRHHRVDDSIRVGIQGTLTDQLTALRKRMEAPRPSVVTPKAISPSSSAATRELLREPMTSVVNNQQKLEDALTALQQQFREARQTSLRIKQTLHHALALYEQEKPLHHAVGSSSPLTDQLFQQKAPDYRQIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C857</accession>
    <name>A0A8K1C857_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="717"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="745"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="785"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="871"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1504" mass="169185" checksum="C53B30338E757CA3" modified="2022-08-03" version="1">MYVLASVVGFPLPFGQIVGSVAGFPTVLVSLRVLWRNAIRQDSKLRADVHQQLLVFVGQASMTYIFPLYFLAFTSLSSYAQSAFTFVLPFIKLGLKNHFGHTLRGIDDIKPAFIVFNVDVFCALFVANCLQRSQSWVNTLLIMIVDIFQICISLYDIHHVMSDIRSLVCLNMFDGSLLNLSRLHVLILCGHRAFPFDRLSFDRVSTASPPRHRSSTRLVQRIAKVLYIAEFVLLIEFTEVMIPIIYSMYLVAMSSLPNRSYYTQTADLDPAKLAHSISMVMANAGLEFLTFLVTSWIISRQLGLSSLHHLAFALEMQRVVIQSTLVLWIFYVIQQSLVHNGVAFAYGVSMALGFPVPFTLVIQSVAIMPTMIAGLYLLWRRTLRGNPSLQADLRRQTMAFLGQVGMIWVYPIYFFAFTSMPSLGQSVFTLVLPLIKLAFKNYFSHVLRQLDDIKPAFVVFNADVFSALYVANCLQTSQSLLNTLLVLVVDIVQMAIPMYDVHAVMLDIRSLVLFDQFDGTLLDLFVEMARSADVRKQLDRRSSSMKTHISRIHGAIDRRVVPPRNQVLHLSPLPVSHRTRLAAKISKVLYITEFVLLIEFVEVMIPVIYGSWQETPVEHGRSAIYEVKSSASRCVIIRAPRRLRRGLSLRVDSGLLTSTGSWLVRLWERFQVELHGSFSIQRVETIRAFIATTLTIVGPVQHFRCCLPSLNMSYTQIIIVSIVGQTAGTILAFGLSLVIGFPVPFTLLVQSTLVLPTLIASFYLLWRSALHGNKQLQTDLKHQIFVLVGLATMTYSYPVYFFVFTSLDSSQQSAFTFALPLIKLGFKNYFSRTLRQLDDLKPAFMVVNTDIFNALYVANCLQASQSRLNTMIIMCIDIVQMAISIYDVRVVMRDIRSILDRQRSSLKTTTVPTSLVFARLQGSMVLPIPENVVAGSPSVANVQEAVVVARLNSTRRVRLVHKITKVLYIAEFLLLIEFGEVIVPVIYSPETQQHHTHAVSARSCFAFVSHLWGRFQVELHGQFSIQRVERMHEYVLHTSRLRLLLLGMLTPVPALIVITLIDCFPLVSPDEGSNRNYAFWIRMTIVTTIIVGSNINHYRCCLPSLPMTNTELVLVAFGSSTLVSVSVVFGLSHAVGFPVPFAQHVQSIVGAPVAMLSVRYFWRSTVRGNPALGRSLVRLASANSGKFAMLWLYPLYLFAFTSMTSIQQSMFIFVLPIVKLTFKNYFRRVLRELDDCKPAFIVFNTDLFNALYLASCLQSSHSWLNTLLVLAVDVVQMALSMYDVRSVVREIHSIVHLDKFDGSLLDLCVAVSESSDVHKQPDNKPRPPSTMISSTIHPTGRQYKMTGPPASATYVALLPAADRGRLASLITNVLFIAEFFLLIEFVEVITPVIYVLYLGAMSHLPNRAYYPRLASLTEAELSHSMTTVVLNAGLELISFLVACRLLDAQLKTSSVRLLGFVLESQRSLVQTSLVLWTTYVTQMSLLHTGVDFTLRFSWLRAKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8D7</accession>
    <name>A0A8K1C8D7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_009913</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8D7"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="53"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="229"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="492"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="591"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="676"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="726"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1103"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW58354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1204" mass="135737" checksum="907D2CA897F73C49" modified="2022-08-03" version="1">MGWDSHLDSDNEHDDQYEGHDLDGGSGMGLHMGACVSQEDAWAVISAYFEEKGLVRQQLDSFDEFIQNTMQELVDDSRSIRINPEAQYNPGQAKANTDTIYQISFGQIYLSKPTMTEADGSTSVMFPHEARLRNLTYAAPLYVDVVCQKYQAPSSGPANLDEMEPYEQVETPKEFIGMVPIMLRSQYCVLTHKTDKELTELNECVYDQGGYFIINGSEKVLIAQERMSNNHVYCFRKSGTSKYSWVCETRSHVEHGVRPTSTMYVQMYQRSGGKSAITGNQIRSVIPYIRQDIPVVIIFRALGFVADREILEHICYDFSDAELMERFKPSLEEAFVIQEQEVALDFIGRRGSAINVSKADRIRYAQEILQKEMLPHVGVEDHNETKKAYFLGYVVHKLLMCSLGRIGEDDRDHYGNKRLDLAGPLLGGLFRILFKKLTKDVKTFLQKCVDNGKDFNLTLAIRSRTITNGLRYSLATGNWGMQKTASKAGVSQVLNRLTYASSLSHLRRLNTPLGREGKQAQPRQLHNTHWGMICPAETPEGQAVGLVKNLALMAYISVGSPQAPILEFLEEWATENLEEIKPQIIPHSTKIFVNGNWVGIHREPNELVRTLRSLRRCVDIDAEVSVIRDLMNKELRIYTDAGRVCRPLFIVEDNQLLLQKEQVVKLQNHKVTNYRWHNLLTDGVVELIDTEEEEVCMIAMEPKDVGTAAQHYTHCEIHPSMILGICASIIPFPDHNQSPRNTYQSAMGKQAMGIYASNFRARMDTMANVLNYPQKPLVTTRAMEYLHFRELPSGINAIVGIATYTGYNQEDSLIMNQSAIDRGLFRSTFYRCYVDQERNKSPGGAIGGACEEFEKPGRENCLGLRHGSYHKLDADGLVAPGTRVSGNDIIIGKTSPLPVSEDSSLEQRYQKRDASTSLRSHENGIIDSVMLTTNADGFKFTKVRFRNIRVPQIGDKFASRHGQKGTIGMTYRQEDMPFTVEGITPDIIVNPHAIPSRMTVGHLVECLLGKVSSQTGDEGDATPFTDVTVQAIADTLHNLGYQRHGNEVLYSGHTGRRLTAQIFIGPTFYQRLKHMVDDKIHSRSRGPVTMLTRQPMEGRAREGGLRMGEMERDCLISHGSANFLMDRLFANSDAYRVHVCDICGIIAIANLRKMTFECRTCRNKTQISQVHIPYACKLLFQELMAMSIAPRLFTLGNPNHSKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8H1</accession>
    <name>A0A8K1C8H1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">sphingolipid 4-desaturase</fullName>
            <ecNumber evidence="3">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8H1"/>
    <dbReference type="OrthoDB" id="200948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="11">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="351" mass="40264" checksum="BE6C34401F3DF083" modified="2022-08-03" version="1">MCKATTTTAAKEESPMVHPELNAKFVKTSAAQDDFHWVGSDEPHATRRKLILAKYPQIKELFGHDPNTKYVVAFVVALQTYCAFQAQHLGWPAFFALAYIVGGTCNHAMMMAMHELSHNLGFKRMMPNRICGIIANLPIGLPSAISFKRYHMEHHRYQGEEGVDVDLPTQLEGKIFNNVITKFFFVVFQVFFYALRPLFINPKTPGIWEFYNWVACIAYNYAIYHYAGPFGLLYLGVSSVLGSGIHPVAGHFIAEHYVFILGYETYSYYGILNWFTFNVGYHNEHHDFPYVPGSRLHKVREIASEFYDTLPSHKSWVAVIFEYIFNPNIGAFSRIKRQTLSADQKNKMKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8L9</accession>
    <name>A0A8K1C8L9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8L9"/>
    <dbReference type="OrthoDB" id="447842at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035539">
        <property type="term" value="F:8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04678">
        <property type="entry name" value="NUDIX_MTH2_Nudt15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000060">
        <property type="entry name" value="Nudix hydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099">
        <property type="entry name" value="8-OXO-DGTP DIPHOSPHATES NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099:SF5">
        <property type="entry name" value="NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="16790" checksum="D46C2D74BB73535D" modified="2022-08-03" version="1">MSATSEPVVRVGVGVILTSKQHPGCVLIGQRKGSHGAGKFALPGGHLEMYESWAQCAVREIKEETDLDLDEHELKFAYVTNDPMEDEGKHYITIFMQASVSEGQVPRNMEPNKCEGWEWIPWESLRTKENLFVPMLHITRSGFAPKFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9D9</accession>
    <name>A0A8K1C9D9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9D9"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="13"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="12692" checksum="E7B75231A9A2634A" modified="2022-08-03" version="1">MGRVFKVYLDSNRVFRCRECKAHLTSVEEIISKNFQGRSGKAYLFDKVVNVTTGPPEERVLMTGLHVVVDVYCNACWSPLGWKYEDAEDEKEKYKIGKYVLELAKTHRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9K8</accession>
    <name>A0A8K1C9K8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010247</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9K8"/>
    <dbReference type="OrthoDB" id="551672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="BZIP" evidence="10">
        <location>
            <begin position="178"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="427"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="203"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="54042" checksum="580E891D80D29B0A" modified="2022-08-03" version="1">MIGSDATPWLDMSDKELSDQVAMHDDLFPSDPMHGLLLDDDVFPGATDLFADDAMTEYDTSDALTDAASEMSTPPPCFDDDRSTPTTPTTSTGCTAGPSVAPKLAPVSPPHAETTTMPRMPVAPQPLQTAAPFTPPAMLPFAFPVACFPPLNLNQKRPLPEMLPNPAIGAVDASMCKKSKREIRQMKNRESANRSRMKRKNQLSEMAVEVDELTKTQHELQNTIAALRAENKSLHDQNAFLRSLVTMYSDSSRNVQLPPVPQQAQQFTELPPLPDLENGSNARSNDEDEELEFLRLTKKPKSVVRSAATVSAASLGLCASVFGLTILTDSDNGATHSGHVRRAGRVLHSLPSSPMESKCMPTQSWMEWSNQMFTSSWNYLATSDLAYAVIVNVISFIAIMVLYHMYQRFFGSISKPLKEKSSNYRWEAESEDSHSVQRGATTSRQRRPVQSSSTHLPTKHRSVSWQDVRVVDGQTHMKPSTLPHMHVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Z7</accession>
    <name>A0A8K1C9Z7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fanconi anemia group D2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Fanconi anemia protein FANCD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27031at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007129">
        <property type="term" value="P:homologous chromosome pairing at meiosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029448">
        <property type="entry name" value="FANCD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32086">
        <property type="entry name" value="FANCONI ANEMIA GROUP D2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32086:SF0">
        <property type="entry name" value="FANCONI ANEMIA GROUP D2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14631">
        <property type="entry name" value="FancD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="779"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1303"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1303"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1326"/>
            <end position="1346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1357" mass="152278" checksum="7285E76BA23626A5" modified="2022-08-03" version="1">MGVFQQVWEVYKEGGCEVTVHKTIASQLGTRSDGSESATVRSFMTEMERYLTDPEMLLLLLSVGLGGMFESQSSFVGILLREDVLQSPLIDFLLEKLSELAHMEHETTQMMERNVPKLILREIRWVDHVVDSKELVEKLISAMPAFPVALQRDIIYILPEIARDEDSHMVIDALLELIRSEAELVVCCIEALGNFNVLTEQTSEVVGCILERLDSSPLTDLPAIVKYLVQEAPATDVSLIVNELREKLSATLSFSETNQPRRGGNEESLILGSIAQGFYFREELMKMFVSSINKSDADGGSGLRLLDVWVLAAGHSIIRDRAKIEQIVKRKVTNGQLTPRLVIDSIKGHANALKSHFSSLLHVASMLLGQTNQTCVSMGSLLYELLFEEFSRSRDDGRGQIALYQGEIISSLLGHCFSTTRDITDAALDTFVALTSDDISFRENVQRNDYVLTPMKRRLRFHVFLPVIKQLLDTTETGSAGHIRKVYGILFAVAGAEDAELCNLLRKQAFHQELRYRQFGIIGAVSRMNQLLQSFREAALSEDERVPDTDVARTLNRCNLELFENSSSNGACVSFLLEELSRWVDGMKLDKYSNLMLGIISEFYMEVLSSRFMDDYDHRKYLEGGYKKPVLGRTMNADLWMCLDVQQCPVYLKIFDLALSPNVAERDSLLYLNTLVELVLTCARRNNQVTEINCVLICPIQMMERSVIEDIAGLDHSAQNIVCTTLWHSINWIRTLLSFFSAEPDNYYVNKVVERLKNLAHIEAMLIEEAVHACPTFAPPGTEMSSTKQATKTLNTEKKKPGRPSKNAQVVNRPALVRQSFLPLKQPALKILTFPALWNEVITESSAAPQSGPAADQLVRFLLLKLETQLETTRSSMKGKFSFQRTDGSMVIVPNAAVEVIEAGVFQSCCKYAQYYLQQYKAESEKEDDADEDRLDMASEILQVYLRIAVGVFNSGNSNSEHLHLIQLCQDFFLPKEQHIELSSGEAELKTQVLESCFHSSLEFSCIVKDSLSTAGVFIQSLQTILSLEFGFAPDQLLAQSREVSFRPNNSSTAVATMNNKIAQLALSYLQHDWSGGDKKYVYKSSELEIILRGYLHHGSIVLDQVQTLGLNGILELLENGGTEIAAFPTLSKKTMGIYHRVMFDTLVAATSRLDFDEDKNNVPLLLNYLTQSVLLFKLLVAITKSYQKSVIVATVLKKGRKYVEIILRAMPFLQAHFLDHNDMIMKLISEVQVATRRMQVLCAHGKLIKDATAGAQVPMVKKLLERFIYRGEELARAHGLLDAYTTGVLKNRRIDGTTISKEELEATHEESSESEAETEQGGSSETDDEEENAANEDAEEKEEGDGASHHPRKRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBZ9</accession>
    <name>A0A8K1CBZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C65 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBZ9"/>
    <dbReference type="OrthoDB" id="18915at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1300.20:FF:000001">
        <property type="entry name" value="Ubiquitin thioesterase OTUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="8">
        <location>
            <begin position="55"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="30168" checksum="B46DF35637FCC37E" modified="2022-08-03" version="1">MEDEQPSASDWMESLGKDGPLISDPTSVLLLKAEYLGNANPNFLHGIEALNKHYEGMRRVRGDGNCFFRAFIFALCEQLLTNKEDVAAATALRLRILDKIRQSKAELIAIGYSEVAIDAFWETFVDYLEAMETRTHDELVQDFQTEGGECEYLVWYARLLTAGHLKRHAEQFQPFIEGLFPGLTVEQFCAAEVEPMGKECDQPQITALTEALQVRVKIEYLDGSTTAEQDLQSYICGTNAEGSEDSINIHVLYRPGHYDILYPRKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCH5</accession>
    <name>A0A8K1CCH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Carbamoyl phosphate synthase arginine-specific large chain</fullName>
            <ecNumber evidence="14">6.3.4.16</ecNumber>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Carbamoyl phosphate synthase pyrimidine-specific large chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Poli38472_000525</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Small subunit of the glutamine-dependent carbamoyl phosphate synthetase (CPSase). CPSase catalyzes the formation of carbamoyl phosphate from the ammonia moiety of glutamine, carbonate, and phosphate donated by ATP, constituting the first step of the biosynthetic pathway leading to pyrimidine nucleotides. The large subunit (synthetase) binds the substrates ammonia (free or transferred from glutamine from the small subunit), hydrogencarbonate and ATP and carries out an ATP-coupled ligase reaction, activating hydrogencarbonate by forming carboxy phosphate which reacts with ammonia to form carbamoyl phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="14"/>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="434at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000012">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000006">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000026">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="10 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="553"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="1095"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="22">
        <location>
            <begin position="1357"/>
            <end position="1504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00069524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00074189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="TMW60483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1514" mass="166807" checksum="5025EB213925067C" modified="2022-08-03" version="1">MLRLSPSLRKRTPLHKATGARLLQAARSKVDRTNAPRFTTPAVLEFEDGSRFPGVSFGAPKSMAGEVVFTTGMVGYPEALTDPSFKGQILNMTFPMVGNYGVPCTKTLDEYGLNKFIESDRIHAAGMIVQDYSSHHSHWNAASSLSQWLEREGIPGIAGVDTRAITKKIRAKGAMKGRIIVEGSDKPSFVDVNEENLAALVSTKEVRVFGKGNPLKILAVDCGIKYNIIRSLVSRGAEVKLVPWNHDIASEAGWYDGLFISNGPGDPAILKETTEQLRRAMDAQGDNVKPIFGICLGNQLLGRAAGAETYKLPFGNRGQNQPVNNLKTGQSYITAQNHGYALNGKTLPSDWEELFVNSNDGTNEGIIHKSKPYFTAQFHPEHCGGPTDTEFLFDVFLDAVRQKEKGPISSLVQRPEVIRPQVKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEDIETILINPNIASVQTNIDRSSEAQASNVYYLPVNADFVEQVIKRERPDGIVISMGGQTALNCGVELHKKGILDKYGVQVLGTQIDVIEATEDREIFNLKLKEIGEKIAKSFAVNSVDDAVDAAYKIGFPVMIRSAFALGGLGSGICEDEKELRSMAKKAFAGSPQILVERSMKGWKEVEYEVVRDSANNCLTVCNMENFDPLGIHTGDSIVIAPSQTLSNREYHMLRETALKVVRHLGIVGECNIQYALNPESEEYCIIEVNARLSRSSALASKATGYPLAFVAAKLALGITLPELKNSVTKSTTACFEPSLDYCVAKIPRWDLSKFENVSTEIGSSMKSVGEVMSIARTFEEAIQKALRMVDPGNEGFEPRKDEWSREELKKALARPTDKRIYQIAKALKEGILSIDEVHQITKIDTWFLTRLQRIADVDVNLTAKSALEAVTKEELIEAKQLGFSDRQLARMLSCSDDDIRAKRKHLGIEPSVKQIDTLAAEYPAQTNYLYMTYNGQEHDVPAQDPNNGVMVLGSGAYRIGSSVEFDWCAVSCIRTLRKLGRRAVMLNYNPETVSTDYDECDQLYFEELSKERVMDVYDREGVQGVVVSVGGQIPNNLALPLHKAGVHVLGTHPTMIDSAEDRYKFSKLMDAAGVRQPQWKELTSMAAAKQFAKDVGYPCLVRPSYVLSGAAMNVAYNDEDLARVLGEAADVSPEHPVVITKFIEGAKELELDAVAKDGVVIAAAISEHVENAGVHSGDATLILPPVDASSFYINQIRQCGEKIAKALNISGPFNAQFLAKGADVSVIECNLRASRSFPFVSKTTGSDFINAATKVMVGESTENDNLPELFGEKRPEGFVGIKSPMFSYTRLGGADPLLGVEMASTGEVACFGKNRHEAFLKALISSNFKLPEKNILLSMQDKFTEEFVHAAYKMHELGYHLHTTEKTHEFLKKYDIPSTKLAFPLDEDAATEENVLHYLREGKIDLVVNLPNSESKQIKNNYLIRRTAVDFSIPLLTNISLVKLFVEAMAIHKEKPLLGLDADSLFDYYKREKEEEAWTNPHDFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCI6</accession>
    <name>A0A8K1CCI6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TMEM104 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCI6"/>
    <dbReference type="OrthoDB" id="294541at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="150"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="57563" checksum="4123C21EAAE0697D" modified="2022-08-03" version="1">MAGGGPTSGSYSPLTGFIFIFNLIVGAGALTIPHAFAQVGLLYGALALGLLALTSYVTATFMIEAIAGVNALRKRSRELETGSTPSTREERSEDESEDVTEDSNRDENLTTEFMPLMVPTQDDDRLEKKLRIRSPELGFDFDLTRKMELAQMAHTLFSHNGILAFYTCVVVYLYGDLAIYAVAVPKSLREIVCPRPHPEAVVWECSDGLNSSDLYRLFVILFGVTLGPFTFGHVHKTRTLQLITTVIRHASFTLMIVLAVIGIARGEGRSAEEVIAYEKPTNIATFFGVCIYSFMCHHSIPGLVAPITNKAKVGKVIAWAFLAVLSVYLILCVSATFRFKPDEIDDVYTLNFKKYPIRAVAYFLSLFPVCTLSANFPLICITLRENLHTLAKNIGSETDEQREARHARMSSTRAFFVRNLYALLALVPPLVVAFFTEDVSMLVGFTGAYAGLGIQWVVPACLVYCLRRQLEQERSRSPTDLKTHATNPFASPFVHMGWLYLIMALSGFAVVLITITHGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ3</accession>
    <name>A0A8K1CCQ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47242" checksum="D870ACE61F44F191" modified="2022-08-03" version="1">MPQDDMLDAALALLEAIETEEALRSLCVSSDAGLGRLNDAELASNECKSRRSAQSKKSSSTRQKEEIARLRGEITELSRVQLRLKSRHGRRFAPSSANFELVSMWAAIARRQRRFREKAEAENAKLRARIEGQFSAGQDVASLLTATIGEQTPCLEFSADLESSETRARLDHLYDGRHVAFSTACFADTTTSFRDRQIVERSENQTTIASRDGWVTPFPARQLDQAFWNILCRRSVWEDAESIMEHKCTDDTVFITYRAIATSEQVTLGTLQSKMAIRRYRSDTDSLSDYVMWYVAEPAPVDSTPDELRNLFGCEAVWYRVRESKVGSSGSLRSQFQTSARACIDCTAIPSTYRQETMEIIIKFALQEIKRDFEWTQEALEHELVILSNSMGGIDDNSLLMHGADQECEASKSKTHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCX6</accession>
    <name>A0A8K1CCX6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCX6"/>
    <dbReference type="OrthoDB" id="166440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="418" mass="47053" checksum="B2546D50ED276707" modified="2022-08-03" version="1">MTIKKGSKPQPQRKQRGIGVVVQTAQKGFRIWQSFGMRGKYFASGLIVREGVEAALQTIQASSSANQISNPFVNYSYAVLIFINCCSSYLYGFLFRADHVHRRLACVLTDLSLDFVWGTIMPVVVFMPYARLYLSRNEVGATSTVSTESVETEVEQMLVLSLKAFILSIFPFVSASGNIRGIKRLLEQAKSTARPQEENFQPTSEWQSTASQSEGAPHTFQDRLRRNRTVRVIRSYVKVWSLSHLVHALMVLFGVIILGISIASSNFIHRFEATPYDCQRRLRPWLSTKEACAGRVINCTKAGIQGQPAEIMAALEYFDEKTLSSLTFTECSALEFPSTMQRFKNLKALNVYNSAIVGWSEDFALTSSHLPSIQTVRLWYIDLQCSPEGLYRHPLSSSLEWLSLYDIDITGFVDEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD64</accession>
    <name>A0A8K1CD64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD64"/>
    <dbReference type="OrthoDB" id="126400at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="54779" checksum="1D2CF4D229CD3319" modified="2022-08-03" version="1">MDPSDEWDSMPDARFLEADDLLESIEMETDDLMGLLTYLSPLNRVNDDDMIANATSPMLTVESPHYPLSNSLASDGDGFDSFDDSVWHFSSGIASAPSCSSKRATGSAKCKRPRRTDSNRARDERRRELLNLRQSVTQLEQELSTLQLEKGSVLVPREPSVERRVVPGHVTGAWETIAEHQRRDRRRAEEENVRLRVELDAQLQFAARLERLVRQSLRQRGMDEAHAGNGLQAYIDPSQYSDRSVYDALMRALEHRYQHVDALFGRLGINDIEYSHHGNRVYRRESGVEIEVFHNEVLPVSMEIAGDVVWNHYAHYMAHVPHRHYYERTREVVYANEDTLLENIGIKLNFNGTSAHVREQQVLRRFAEADRIVIMWCSNFHTIEYSERSTAGMIFRRNGCMLFKRPTTLDPNELSILKTSNMTTPMLDGAQFNPGGALTKELTDFLLSEGAASAASMHQMIENMLIHEAMRCKQPQLGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDF2</accession>
    <name>A0A8K1CDF2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDF2"/>
    <dbReference type="OrthoDB" id="75680at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="108" mass="12197" checksum="5883BE65AD0C346F" modified="2022-08-03" version="1">MAQSLEQLSASLANVMSRLDTAETKLTTDAKKVDGPVGGVELREYQLQILARLRDIRDTMAKEGSSVEQLRKERDEARAERDALQKQVTKLNYRVHHLKQHVTVNPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDK4</accession>
    <name>A0A8K1CDK4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_012503</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDK4"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="65"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="370"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="472"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW61312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="538" mass="61334" checksum="4297C0D52EBEE894" modified="2022-08-03" version="1">MGCHHSKASDIVDSTARAVDHKHNGALVNGNNRHGVRRSDRYTLRDDITSELVQHKQVDDISELFDFQDVIGTGHFGCVKRAISKKSGKEWAVKVVKLHNEVDRDALRNEIDILRRLHHPHIVRVLSSYEDQEHMYMVMQLCKGKELYEYVYKDKYRFTEDDVRRIIRALLRAVAFLHSNFVTHRDLKLENLLLENAENPNSLKVCDFGLSTRFKRGEKLQKSLGTIDYVAPEVLDGEYNEKCDLWSVGVICYELLSRVSPFHAPTLDETMGKIFDAVLVFDDAVWTKYSPQAISFVKSLVKEDVDSRLSAEQALNHKWLQDLEQNAENTARLQSSKRLLLTNMLSFSRCRKLKQTALLSVALGVSEDRIHQEMAAEVFHSMDHAKKGTLTRPEFCQSMVECGLSPDDASELFTRINQSKTGQINFLEFMAAVMDHREIGQNTIKEAFSLLDGEKTGRLSIVGLQDVFKNSLVTEEVKEMIASADTSGDGFVDFDEFQDMFRQPNTPLATVEEQSEKRCSTNSWFGSEDVDNHVVSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDV3</accession>
    <name>A0A8K1CDV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">50S ribosomal protein L5, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_012787</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; contacts the 5S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDV3"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000004">
        <property type="entry name" value="60S ribosomal protein L11, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 13" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="14">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="15">
        <location>
            <begin position="64"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00035391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW61596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="174" mass="19847" checksum="9D2703E66E60B0E9" modified="2022-08-03" version="1">MAGDSNNVMRDIKVDKLVINCCVGESGDKLTRAARVLEQLTGQKPVYSKARYTVRTFGIRRNEKISCHVTIRGELAYEILDRGLKVKEYELKKRNFSDTGNFGFGIQEHIDLGIKYDPSTGIYGMDFFVVLNRPGARVARRKIRQSRVGAPHRLHKEDAIKWFQAKFEGIVLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDY6</accession>
    <name>A0A8K1CDY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDY6"/>
    <dbReference type="OrthoDB" id="48682at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Chromatin target of PRMT1 protein C-terminal" evidence="3">
        <location>
            <begin position="34"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="15768" checksum="5AD661704B5F1E4C" modified="2022-08-03" version="1">MPRNRSGRGGNNGERSKRAAPYDARQSRKVNAKNPGTKGGKGGNSAPANNNNGGRGRKNNSGKPGRGGAKGGRGGRGGAKPKPKTAEDLDREMDSYWGKSEEHASKKLDSDMDDYWKNKDAVAESTDEAAKETEAPAAETEAEAPAVQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE25</accession>
    <name>A0A8K1CE25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE25"/>
    <dbReference type="OrthoDB" id="168496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="364" mass="40727" checksum="8E27135D8C287E3F" modified="2022-08-03" version="1">MTMQVTRPEPAMEPSPASKKATAGSAKNFDGDALSPVSKLEAARKFAQVEQEKRVAAASARLTAAKKEHIVKRVEIEQHVGTHSEEQHVTHVVEETKESYVTGVSTFARRLLVSFSSISNNSKDDEENVDNQKEGEEIEASPTRSLLQATRSKLNALIAKNAEDEEDLPSTNYHLKQLGLVSDKINIYAPVHEQQQEIRRRRQSAIRCQEKYMQEVAELPMDDGYDSADDSDYVPEADDEQESGSEDESDDDVDEEEIRRLVEDQSEFDTRVAEARARLQEKKRAKAKKADFAWVPTKLSHRIAAVVALLLVLVFIVFIAEHESGACYFVVTSPTSDDSQRAVCNVVMSIYSSVLRVQQALMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEE5</accession>
    <name>A0A8K1CEE5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative auto-transporter adhesin head GIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEE5"/>
    <dbReference type="OrthoDB" id="161142at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39200:SF1">
        <property type="entry name" value="AUTO-TRANSPORTER ADHESIN HEAD GIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39200">
        <property type="entry name" value="HYPOTHETICAL EXPORTED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Putative auto-transporter adhesin head GIN" evidence="3">
        <location>
            <begin position="241"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="48848" checksum="1A2EF1E35362C05B" modified="2022-08-03" version="1">MLHTPSRWAGMLWRLYAGVGIALCLSGALARGLSVTRAEVEAIPPEERTGPDSFRQQWLVIQSGSDVGHVQELVLGTSCDVHVQYMVNTGCATCVATVQFLGSNRSLLNRYLVTSRDAELSIQGSESDLHMEVVVHRAASLSSVTLQSSSEVVFRDSVLVDDNSSASVSVQVTGNGKIYLPEDATYNVGQFITKVAGPGTVSITGKQINADSVDIQVQGNGSVCVATQGLQVKRRTTVQETSSGSISVDVSHFETDSLVASVQGSGGVSFTQPGRCNSANVATMGSGTVHIGPVSCANAEVAVYGSGNAVVRSLRSLYGNILGSGNIWYEGDKPQSVTGERVSLSSGERAIAIAYQGNPPIRPCLIPPHRPRQENQVVLRPDDQSPSNAEASGNIPSSTPETFSPPPPTSSITGRVHWVVLALLVGAVTFALYEFQSWRHRHRDPNEHSPLLGNDAPVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEM9</accession>
    <name>A0A8K1CEM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEM9"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="13"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="54635" checksum="C4F86D1AF76A0DA5" modified="2022-08-03" version="1">MAVSMPKLSAKGVILVLCFINFLNYIDRGIIPGAPESFQHFMTQTLGIDVTEQNFYLGLLSSAFIASTATFSLIFGFLAKTYRPFVLITIGMSSWVVAVLLCGLSYNIDSYYLLLFGRVLSGVGEASFHCNAMPFINRHAPKENSTVWLGIFIASISVGMAAGYVYGAGLAASPVTWAGAFYIEAGLMTPAVLACWFCIPDELNEVPLDSLHTLHEDLLRGEEEHSVDRSAHQLSLVRQPPRKESFMTEWWRVFKNIPFSLVAFGHAAYTFTLSAFSIFAPVLLIGMGFFESETQVSLIFGIVVVVSGTIGTVVGGLLLDRMSNGNNVSNYRRAQLAVDLSLYLMIITQAFGLIMMIFTKSKFWFLFMLAMTFLFMSAVGPAETVAVMEMFPESRQAMAVAANTVLILLLGDLPAPVIIGWLKDTWAPLCGTVEIDGDLILNPECHNDRSGINHVLLFSVLWMIWAVLLWLGAKVVMRRRQPTKLETIESPVHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFI1</accession>
    <name>A0A8K1CFI1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFI1"/>
    <dbReference type="OrthoDB" id="57935at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="257" mass="29898" checksum="7A9F853FC0BBA550" modified="2022-08-03" version="1">MYSSWSTDLREYHAHQRKIVRHFAPHIPDEVLTPLERRYLIVGVTRIVVVFLVPTTVIILRHLWFWKTPVFILVAVISLVELVMAFYRYLVLWPEGREMRWGYWLDIEIAEDCYKLKILGYYHRKIAKFTGRFPSTMPSSEIRRHYRRRGITMSALFTVAYGILLTLLARAGEAKPILIWVLFLLTIGSGMVVFRFIKMHYIELPQVLILRDHPDFALPEVPHAEAIPFARPVESYQATQHATSSNGDTENSSATAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGA1</accession>
    <name>A0A8K1CGA1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGA1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="28766" checksum="7A19B506C8C00942" modified="2022-08-03" version="1">MRAALDQQPSDEKGTVELILVDMGSLTSVRGFAEEAHRRYDRLDLLINNAGVAFPPQPLSADGYETHFAVNHLSHFFLTTLLFDLLKKSPAARVVNVSSLAHKRSQMNFETIVAESGYAWGRYGQSKLANLLFTYELSRRLEAAHISNVLSAAAHPGVTYTPIADKMVESIFPKFIHGMLKRVISWLPLQSSAMGALPTLYAATAEDVRNGEYFGPARFAGHFGHPVRETSQPQSHSKEEAQQLWQLGEELTKLSFHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH37</accession>
    <name>A0A8K1CH37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH37"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="616"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="639" mass="68118" checksum="2462DEBDD816B3F4" modified="2022-08-03" version="1">MICSSVSVAAIGTACFFLPGSELFGDTAGEAITAVVEAGGHHVAEIFTEGANMAIEMRSGHAVDSAIENLTEVSTESSIERGVEMLVQDATASALNSLHQVLDYAPDALLKAFGIEEAAAFVEEHATSLIIATGEVAKETAPTIVTERVRRGLQPLCRAKWGMLRVTVSAVTIGTFCFFVPGSEILDCLADAAGGFIDFIADAGAEHLIVIVAEALGMAVDEGADHAVDSLVEALAEAGTETSIEHAIETFVEDMATSALESLHLAMEALPDEVLDILGIDEAVEFLEDHATAAIIATSEVLKETLPSLATGAVDTVCLEVALQGADSTVGVALHRQSKQEMAKYLQLKEPDLDPETARQVVKDVYARPVLYLTQYKELTDQELLAKEAELIAAAAIRANSLNFMVSMVASGGVTLFANPFDTISRARGAMLMYHNLSHCRKELNQRGIKPQFPLSISVSAGNAIIILSTTILRELPVPMIKQLIPDQAEGFVKENISLVKPVGAMMTPASVSTWVQDALRHPAVQDAVKQISSELSALVIDVVADAVADTIAERAVEAAEAKEAQEGQKQTENSAAAAARLASLQKKRTKSIRSIAKTKVQRLAQVKKRIPNHSVFVISLILALLAWFFAPWSAVFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHV5</accession>
    <name>A0A8K1CHV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHV5"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764">
        <property type="entry name" value="UBIQUITIN-LIKE-SPECIFIC PROTEASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="533"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="808" mass="91600" checksum="F46B7F05FC4AF958" modified="2022-08-03" version="1">MSEYDGIRTPPDGTRHRRFGVDRRRFTAANGSRGAVVENARDDGRTAQFASVARHVASQHPRHRDAPEFNFEDRSSHERNGERRATGTGKYMAKPRGVGMAVRPGEAIMGKNEEEQRLIKNYNPPKTQDSFLATIEKSKRPPTTLATGLPRRVLRQSLESASAPPPTSPPPRLPQRVIVKPTTKPRDEWKSTRVPITERYGKLRVELTPPVKRARTSVKKDREDSPPPCAIAFTRTADSNPLRISSEIQHTGPSAARRYSLTQSAGENSPPIPRRKSRRLAKEAQAGDSADMPIQLDSDSDTDSAASEDQQPPAPAPVDDIDPEELDDDSFDLAQIEEDSIVSVKNCRAWWGKRACLLDLFVDNQYLRFCSIRGVKEKWELRRNVCIKHKKVEELRLYQWNQQEADNLDTSNPVEKIMATTSLIAFKFPIPYVRNKGEWRVFFDPSSNGRTGEDFGTARDCLQWSEEQASILDINHVKQYVQAILASDDHHIITNPPTPEKKESKTRKRRMNRDGADATRLTYPLPPCSVDIVTITAQDISRLQPEQYLNDNIIDYYFKRLLLEDYQSDPAIQRNVLFLSSHFYTRLSMGKGPTLADRLQAGYNNVSTWLTRNDFFNRSLIFVPINKSVHWSLAIIINPKLAGVDEDEHDNCDATSCIALLDPLGSYHNKATINRNLRSFLRLEWENSTKAAEENDEVTSSYDVDKVSMVFVKAPQQTNGYDCGVYVLKYAQEILINFQHLLNQAKKDTGPMLIRKAITETKLDTLIASDAFNARDIERKREELEELLAEDTKRYEAILHGDEASSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI89</accession>
    <name>A0A8K1CI89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI89"/>
    <dbReference type="OrthoDB" id="76324at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="15776" checksum="6F79F9154BED115A" modified="2022-08-03" version="1">MPAAPSHELSAPSPTPLVTAAAEVAVSVSMSATESVKRRGMQLSSELKEFVSGFAAADSPDMSIPLEWKLISALLVLFLFLLFLILVLWDRYGKEIGELYTPNVSASARDANDVSPNDVADEYTVYQKLPTFFYEYAPRKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ63</accession>
    <name>A0A8K1CJ63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ63"/>
    <dbReference type="OrthoDB" id="147975at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050404">
        <property type="entry name" value="Heme-degrading_MO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34474">
        <property type="entry name" value="SIGNAL TRANSDUCTION PROTEIN TRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34474:SF2">
        <property type="entry name" value="SIGNAL TRANSDUCTION PROTEIN TRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="107" mass="12576" checksum="1DAF8964C43A3AA0" modified="2022-08-03" version="1">MAITGKIKVISERIMSRGYEPAVARLMENVKTKVRTQPGLLKVETLAQMDDPHKYVVFTEWRSKEDYDRWITSDECKECTQKINELLDVPGMRTRVFRIPQEDIFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJH0</accession>
    <name>A0A8K1CJH0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJH0"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45153">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45153:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="471"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="61456" checksum="DB9BD6B8E287367A" modified="2022-08-03" version="1">MSSPASIVNLTPLEAAEVKDQEADECIALGDLDGALQALHKAIYFRPDHAPLHAKLARVYWDLCDLKSAMASYRKLFAVDRNPSQRIKDQFAALLDLHAYSLLTLGETPTVVIAYLTEAIQLNGLDETYWLHRALAHIQAQSYEKALKDVDHCVNLNGKEVEYFVLRAKLHWKLHVHDRATNDIHRAAALEPLHPEVIEHAQRLRKESEAIYARACQHLITHEFAEAIKCLTSAAEIAPEETKIYMARASAYRELSDFTTALKDVDKAMSCHKKRFEAAQKQRNQVEQSNTDLTKENREISTMRILILNDMALQCLRNKSYQVALTAMNQVIRGDLELRQTYHEAFCDPQYHVNRGDAYRGLSNFQAALADYHHALELLPDSQDVKTRVALVHYQFGIDLFNQARFDKAELEFIKAIEQDGNVSEYHVRKGDSARFQEKHDVACVDYQNALALNPSDDEICNKLRQYSIETTPMRRPAKNERPKPQKQDEETLREARSAHSASPTALEQALASYQKKNKVVKDLFHQRPTLPPATKRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK22</accession>
    <name>A0A8K1CK22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK22"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="6">
        <location>
            <begin position="96"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="37736" checksum="3B4669A5F4386E41" modified="2022-08-03" version="1">MSKSTRIQFSLPQLVMGAMTGMLVPLMWCEVKGVAKMREHPVFHVTPGMPKVSDMWIALAMAVGLIAIRYVVSKAFYPLSRAILPPGVRESAFRVDRLATSLFKVVFFTWIAVLGYDVIKDEEWFPVSLGGSGDIVKVFKVFDVAPSTSLKYYVLLQVAYQMHSLLYVLLMKPLDGDTMDFVVHDFTSILAMGSSYLVNYLALSATVGFLNDACDIFQYAFFIATDSERKPVISVMYLVLLVIWGYTRLYVYPVEVISNVFVELPGNNPNASRAYYWSGETMLCAMFGLQAWWFFLFAEKGRRKLMKKSPYTKIIGESKALKPQERRWTSQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKW8</accession>
    <name>A0A8K1CKW8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKW8"/>
    <dbReference type="OrthoDB" id="108594at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="500" mass="55976" checksum="3195FF4A91936615" modified="2022-08-03" version="1">MSPFYAESAELFNRDAPFPIQLSHPMVGWLQELSAAGLALRWIEFYDFLKGRVAVAELMRAITGTPCSGVKGDSTCSLGAQVIEPSIESTESYISMCMGLMHSRGVEVVMMLIDMERPKWYWTLYSLFHASATHSIRSLTTWNMGFAADDFRDLVKAPQPLQVIYPRDQLPSAPKTGSFVVLNTDAQIYFDQNRRNEDEYVTTSAATTPFRVIGADGDMISILVPCYGECWVQISDIVSTHPDPFESDPEKQWNLTSHGITHFEFKYNDECATFENLGLLKFIGQPVTSIVIEKPGDIEGEVFDLDSLLLFCPNLTELSIKGLQLASLDVFVQAYESGICRLVSLDILGCDVLDQDSVASFTRALGDPSTAISRTLNHLRASLVDEDRVPDDEVAQMFLSALQTNKRLSFFELQVNDDVRETYKDEVEGLNGSCLNFVSYPLPIRSKCAFLSVVQHAQTQAKDGPLARMDTFVLSRIIDLTAEPQQRSVVLSWRTHMFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL22</accession>
    <name>A0A8K1CL22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL22"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454962" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="30"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="26953" checksum="8FBD436E8CFC7B8C" modified="2022-08-03" version="1">MVSFLSKLAVIATVVTSSVSALEIGEYSRPTGTEVSGVPGASAPYLRSPCPALNALANHGYLPRDGKNIDSAMLEKAIMDVYNIDWLVAKALASQVKGSITLAHLSTHNLVEHDVSLAHSDFSYGSDMAALNVTMWEDLSGRAVDNTIGVSEVAAAREKRIDVCKSKAGGCDFGLKQRILGALEAAVMLRGLGGKNKETISLEYATSFFVDERIPDDYQKPSTAISLANLLSTATKIDLKVTWIDILEFLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL72</accession>
    <name>A0A8K1CL72_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL72"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="762" mass="85382" checksum="915CEA2CDC5BEB0C" modified="2022-08-03" version="1">MASAKGRRCRFPLIKLVLALLNLGSTVLTIFSGLAENPLLVLLTGKYDPLRARLQDGSINLEIASTETLRLDYITPLKEIGTDFRFITAPRRTPYSTGTNRTLCPVVNSINASTISVCYDDFFGPQGARRFQIPVFSISAPGCKVLNLKPKWRDDCIKTRGNATACYQYIMDNFEALQENRVARVGVVSDWGTQGAAFLKCLGRPFKTFDYQTDMVTHQAFWAGASWHAQIQTSDCQAKPLSQTTDLKWTLFQAMAVNDACDIVMALPQPGWFSTIVSGLYSIVSIVLIVRGVVAFLLQNRSAGYISNEVRYSKDRRLARYCMPFMSFAMLLTEEERSIVVFKGSLLIASDVWMNHWLYITLSILDSVTNVRLSYYTYQLGTGYVIYRVNFQNFLFVCTALTRMSWILCLLHTILRQVFKVAIRSLKSMQVIRATTRDKIERYIDGSTIFLSFKVYNILLFTFFLVMLLVKKNTTFMIRGNPYKPGSYGGIPKIAGFWKSELMCDFVSIFSVLLLCGQTLGTLLMLTRFRLVADNNVMRLLQQRYFWVGWDGLMAAQMLGLDPMHDDLLIEGHAYTKASLGTILQLMYQSGPSAFVHLAGDYIFTSGGFTAEPRTIHFPVRQAVAMGLCISVKGSQRNSTGAEGEASTIASTNRISLHSRRQAGPGAAYRIDETATEDSASTEPLRGTFTKAENTSIFDRRLKLVASGYLGQLVLVDMADPGSVSVNKETGLREYVLTDALAKISILDIRYLLKNDKKLRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLI9</accession>
    <name>A0A8K1CLI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable pectate lyase F</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_011433</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLI9"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423138" description="Probable pectate lyase F" evidence="13">
        <location>
            <begin position="18"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="252"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="329" mass="34924" checksum="6E40F0328CB2A31D" modified="2022-08-03" version="1">MLTKFAAVAFAIGVTSALPVPTGTWPESTGVVQNPAPLTIKAGEVFDGKMQTYERSDITCQGQKESGKKDAVFLLEPGATLKNVIIGKNQMEGVHCDQHDCVLENVWWDDVCEDAFSVKGGTASSVTEIRGGGARYADDKVIQHNGLGKVIIDGFFAQDFGKLYRSCGTCGAKTREVEVSNVYVVNPKSSVVTVNVDNNDKATLKNVYVESTKKNLKVCAKSYSTDGAEPTEAGSGADGKICIFEESDIHLNQKPSGSASNSTTVPTTVPSTTPTTVPSKTPSPTNDEGSDDDETPEPVDDDDEADGDADASSSPTPAKTGCRTRRRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLW6</accession>
    <name>A0A8K1CLW6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLW6"/>
    <dbReference type="OrthoDB" id="47459at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477005" evidence="1">
        <location>
            <begin position="24"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29036" checksum="7706783F2DA010F6" modified="2022-08-03" version="1">MVLQKTLASLVAASLLLASPAIATQPREPVVGERLADDASAISIADESIAEAYRIWSSNGWKVLTNTSGILNEAKPVSGVFSSANVDLTRATAIVDAPAQALFDLLITPQGFQLIDPLSNPEDFAKPPLQTFSTTKWRTKSPADKKRLDSVRTEAPIPGLTTREFVVLNAVDSSTRIFVSKSVQHKADPGCSIYGPASCRGISSDPVRALNTFAVSTEPVVGDANKCVVRLINYADLSAAEIPSSTMNQINFNFLPEMVERFRQHFATST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLY0</accession>
    <name>A0A8K1CLY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLY0"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="46"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34276" checksum="1E6DDDF3AA3F060A" modified="2022-08-03" version="1">MKLQLGLQRVATATGRRGSRAQSTLSYRVYEDTSSGKTPTKTAFVMHGILGNKMNWRTFSLKLANAKPDWRFVTLDHRAHGDSPSLNAPHTVSACSEDLLRLADELQAEPDVVIGHSFGGKVAIGYLEEAQRHSRKLPEQVWALDSLPGDVTTDYSNRKLTASIERVLPVLKTIPLPIHSKNKLIEDLQAGGLSLGEAQWLTTNLKLISTQPEAYDWKMDVPVIEELFASFLATDMWPIVLDSPPETEVHFVRAERSKMWTPRIIEYLPTLKDKGVHYHLLPKADHWVHIDNPAGLLDILLKNLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM73</accession>
    <name>A0A8K1CM73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM73"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000005">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="118"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="314" mass="35689" checksum="A988991BD575D88D" modified="2022-08-03" version="1">MSATDAITSAGGGPTEWLEHLRAGQLLSELELKQVCEIVKQILIEESNVQPVSSPVTVCGDIHGQFFDLLELFRCGGEVPTTNYIFMGDFVDRGHNSVETFEYLLCLKACYPDRITLLRGNHECRQITQVYGFYEECVRKYGNANPWKYCTDVFDYLNLAAVIDGRVLCVHGGLSPEIRTLDQIRTIERQQEVPHEGAFCDLMWSDPEDIETWAMSPRGAGYLFGAKVTAEFNQINGLELICRAHQLVQEGYKYMFPERSLVTVWSAPNYCYRCGNIAAILSFDENLEREFKLFREVAESTENLGQRALVPYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMD1</accession>
    <name>A0A8K1CMD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438868" description="Fibronectin type-III domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="408"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="541"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="651"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="795"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="936"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="1410"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="1673"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1821"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1949" mass="211834" checksum="2B9BD1BC272F7FA8" modified="2022-08-03" version="1">MARRVGLVLALLACLSDVNKANAIRKSSSFVTPTYGTADSLTLTTLVTDAADLHYAAVQAGSAPLDASAIKNAAQRCQSVTREVVCSPPENEEDPLIVRAETIALQKAQKVERLLDGLAPNSTYDVYFVAEVPNSNGVYGTVLSVLGTTTHPAPPEMVNVAAVATNASAHAMEVSMSLSAPGVAHMAFIPSEQAPERFVLDDVVNHRALGTNAVFVSEARLSWDSLEFQFVREGLTSATEYDLLLVTEALGQGGVFSKLHRMARVARTHAQAPDLTSLRCLACDGSASELTVTFTLGFDAQDLMRASPQALPYFSYHLHYEAEAVTDVIGENAEGTAKDSVSGVFVIGNVSSVEELHGLSRQTQTRIIGGLASGTSCQLSIVAETVDSFGVSGRRATVSTCETHHKAPKIVSAQIEPTNATVNALTVTVELERPGDVHYLAGNRMLHSIRNSFHHATSISHLRELIRERERRDDVELLTGVVRGIGFGADADQGNRGTFTVDGLADATAYSIVLLPETTNSHGVLGRPHEELLEATTNENASTVEIVEVTPVSGSLSAVQVHVDMSKPNDLLYYCVDPPVQTTNDEQIADPCTELETASRERTSGNNFMFVVGSLAEDTIYNIQLFAASARRNGVVSLKTQPQVVRTHRRAAGILSVQAKPVPARTDGIALSVQVDEPCLVHYAIEQAQLDGKEEAHEPLTADIVVEQTPPQQQQHHHHRHHHHHHHATVNDGSRKIVRRGNIYAAVHALDLLLDGLSPNATYNVHVVTESTRHETQARSGVYSSIVSSNTTTHAIAPVIVKATADAAAGTIDSIVLTANLSAPGYVHYHLSDVDFADPSIIRGDRNEPNGVVTPHIVRGVFMVEASDIVMEVINGTNDTKPMEPLVYARNLTIHGLRDGTTYHVSLTTETLDSQGVFGEFPPPILVITHAQPPQFEPPTFHVGPVPGSSTSLVIQFHLSELGEVHYALFFRGLIDDRSDRNQEVAVEEGVDDNNETTPRWPPVSSSYNITQLTASMLKAATVDDLGEGVWENGTISVSRDDVLRHKLTEKKIEKLPPNAVFDVCLVAETAASDGIFQWVDGKHACHRVVTHADYSNQSILMDEVEVMPVDGRSDAIRIEMAMSKLLSAPTSTQANMESNPIDWITDMTGRVPYFVLIDGKEGRSDFFHNSFAESKHQRDLAVFKDAVPGRGHVAAAGILSHVTGENETMITLTHMIDGLDANHRYFFFFAYETVGSDGVFTKVNPHKYRSNDSKSENEGIEVTTHEHAPKLTRYAAYPTYGNTTRISVKFGVSCSSCTQAIAHLLAYESGCPPPTMEILKTRPTVEPDEEPIAYSDHKAPCQEPVALRRVVVDMAERQTSRNDIEEDFDDVFRPNSTYDVYLATETADSNGVFSNSFIHTAATTFAPAPDFTYLSIKPRKGSTTELLLEFELARPGEIHYMLGKSENAEFNATSPYNISSKSLPTEKHHHRAPHFHNYDREVVRMRRSVKVARAHERHVEVLDYLTPGTPYDFYAVAESIEDKGIYGDIKYVKEVTTFNNAPIILVHSAYPTAGSTSSLTVGFRVDGPCLVHAAVITSTLWAETTHVANGSDIYGNRLAMHDQLVQQKTMTIEESSLEEIGGVVDSGWRELNIAVPRAGTNYTVHLVTETIGSDGVFGTVATHYSVNSHAEPPTLHNVSVSPSDARVDALTVSATLTSFGHVHFAALRRGERFQSASPAASGAISVNTTADEIVSFVIDGLRERTTYDVYLRTETLNSGGVFGEWTEHPIFARTHGLPAQVLEDLECNVLPSCETMGRETCTRVPNMCGECLDGFSGADGPSNEPCRAISSEPNDDKRRSGRPTIKISGVRINPRRQKHSSPPMEAMELPQETVVESPPEPIEESATSTPDDDSTGAAACPFHAQLVAPGQCECEDGYEPDHTGTACVLASMSMLDAMTSPFHPSRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMM1</accession>
    <name>A0A8K1CMM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004102</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMM1"/>
    <dbReference type="OrthoDB" id="118256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479833" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="25"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="11">
        <location>
            <begin position="126"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="10">
        <location>
            <begin position="181"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="417" mass="43256" checksum="3AED762EED7D6FF5" modified="2022-08-03" version="1">MKVSTLLRTAVVVAALLSATQVDAKKVKLCDADGHAPTPAPSVAPAPTTKTPPPTDKNPVAEPVATKPPQSQSGPVLGAPGAPAATGAAPTAAPSAAPSSAPAPPSGGQQTQAGNVKASFSYKGKDCGGPGSYNMVTDVKTCARTPHNIYSPVGPMSDDVTIVFRGPMTIHNIAVFDGSSGSWNKVSSYKEGGEANNLVFLNNRNIDYTGQSAPQGFAQKDGRGNAKESTAFGGELGGATNPDGFTIFGDEKTGAEVNIFQNKKCGVDAECKGYYDKDRAAMAGWAGGKKIFVTKVRMPHGGAPNLPAIWMLNGQVVRSNQYQCNCRGLGKAGGCGELDIAEVIEKDLNVVATHYYFYDGGSAPGHDSWGKRPVDAPATYVTVVDESFGIKVIELGADDFDFNSGSISQDVVQKWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP39</accession>
    <name>A0A8K1CP39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP39"/>
    <dbReference type="OrthoDB" id="68234at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="308"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="362"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="117"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="59298" checksum="BF8EB61E06A2817A" modified="2022-08-03" version="1">MAKANGERSFGMTLEQYKVASNEEYPCVSYVFPQSAASRAGMQPGWAVLSINGKSCRGLSVRDAAANFRDRSEVTMCVDTQRTVPTPPLAQARPVTSSAVPTATAVPAQSAGQSTLRAAAAPPSSTRAVAPPVSSIPVTSSSVPSQSAPPSAPVAPSAPAQTTTVSSQPAPVTQAPVPAASTNTSRVNATPVVTQTPSTMAQTPSASAAPSNTPRSVAKPSDDATQSSTNTTRGAGKKRGRQSTARSSPETSTASAKKPRARTSSVNLADAWDSDDPIVLVDSDTERSVEDEEVDPPSGRRRRYSTRQSAETGRPRRSLTVDRLIAMGFTQEDAEASVVAKGHNPEACMLWIVSRLEEKHFVNELNQASIESERAKRAEEEKLKKQESETLKNATAFTTLFPTSYILSEESEAGAFKQMLSSTIGSIDPDTLLRTLLTKLLQLEHQAIRWYKTAARCYMLQLALRLETSFSSHDALTCCSQQKAPTKEAIASCSCAFVRALHEEEVALNRALFDMPDNHGGVPVQFIRADESMQFSLEDDGFEVVEVPRMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPU6</accession>
    <name>A0A8K1CPU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPU6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477650" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24533" checksum="CEC1E11887E9C296" modified="2022-08-03" version="1">MHGGRRMRAVYVGFVVFAAFARGEKASDSCPASVQVSIAKTEAYQRCQTDSRFAFSNETSVDTSSFCRSEGCFALYEALQKENALSCTAFGGLETLVLWEEAKAKVCFGTMDNTGSSSTDTSSEHTGDANSSSSSSSAAEPVVRDKGSTQSTDTGSSSIVWIGVGNVVAIMLIAACFISFRRKNPAEQRTKEVDDDERLSVVAEYSTLPSTSSDLNSDPQLETPKTTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPX2</accession>
    <name>A0A8K1CPX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 62 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPX2"/>
    <dbReference type="OrthoDB" id="165538at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="763" mass="87350" checksum="62092108A24CD95E" modified="2022-08-03" version="1">MSLLKTRVHPSARALQRSPVMFGFFALFIVTAGLSVWQLTRQPLVQIQKEDVVDLSYLKIHKNDHIGKSVLHPRAAELPNVESEPFDLHQYRETLVATIRETTETFPQYGSAERGIHYRLDNDGIIKQGAHDMVLIVVVFNDEKSWGGGRSPKDFFNLLATFTHPTEKTSVTMLTSNRTEFNKVQRIMKEKIPEYAQLSLLLRNDFNVGSVVTRENRHNDGIQHVRRRMISRYRNFALMSTLESWHQHVVWLDADVHTIPNGLVSKMVKANRDILEPVCLQGGREYDMNAWVGTRTHPKSTQERNGFVPNELDVDRISFFSNTTHDYIALDSVGGTMLEWDMEGYDGIETEGLCYSAHFLGFRCWAAMSLPVTKAPARLTPLQRSPVVLGLFAAFVVTAGVSFWLLTARSSASIRHSLVDSLSYLKVDKSDHIGKSVLHPRTGALPDVEGNPFTLHQYRENYVDNIRETTETFPQYGSIERGIHYRLDNDDIIKQDAHDMVLIVTVFNDAKSWGNGRTNDDYFNLLATFKYPSKKTSVTMLTSNRTEFNKVQRIMKEKIPEYAQLSLLLRNDFNVGSVVTRENRHNDGIQHVRRRMISRYRNFALMSTLESWHQHVVWLDADVHTIPNGLVSKMVKANRDILEPVCLQGGREYDMNAWVGTRTHPKSTQERNGFVPNELDVDRISFFSNTTHDYIALDSVGGTMLYVRADIHRQGVLFPHHYIIGSEWDMEGYDGIETEGLCYSAHFLGFRCWGMPHEVIHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQH3</accession>
    <name>A0A8K1CQH3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQH3"/>
    <dbReference type="OrthoDB" id="159196at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="69" mass="7989" checksum="D6A4D83E7D43914C" modified="2022-08-03" version="1">MANTGGLFEKNPRSVRITAWLLAGAAFYVWYQHDKKTEREFSAGDANKWNQEVLRKTGTKSERERANEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQI5</accession>
    <name>A0A8K1CQI5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQI5"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="55"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="106"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="170"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="170"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="224"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="224"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="293" mass="33793" checksum="1032C921633A49A7" modified="2022-08-03" version="1">MEPRSTKRQRMDDLIEKSMALARHQYVGGGAGGVSVMAASRNTHTNEELRGGMATMPARKGTWTKEEDARLRALVGRYGRNWAVIAQSLPNRDRKRCRERYINHLDPELAWRQWTTEEDKTLEQLYGKLGSQWSRIAKQLTGRSPDDVKNRCFQLRPQQQPQDEGAESTTQRRSSHAWTHAEAEKLRAVVGAHGAKDWFFIASQLPGRTDLQCRQHWFRVLQPSITKGRGSWTPEEDKILCERVKTIGTKWTEIAQDLPGRLGKQCRDRYMNHIDPSIRKVPSRSCMPVIRMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR47</accession>
    <name>A0A8K1CR47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR47"/>
    <dbReference type="OrthoDB" id="77315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="24306" checksum="63B24E888B70A427" modified="2022-08-03" version="1">MTDDGVRLTEPLEQYRAKTLRAEVYRLHLKVVRRGAELNDHKDGYLALLRAYQRENAPEEEERPVVAVIQDSQDRCAEERSEPRFTLADLHDDACVSEVCDVSDEEVEDDLPEEEDALVNVSMESEKADSSKEVSIDRLTQLQVDTASFELLVKKQLHWETRLDVCRRKIRELEALMKEPCVVDVRHELMYYRREYKRALTQLLSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS00</accession>
    <name>A0A8K1CS00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MORN repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS00"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="43495" checksum="E9CBD50A8D366C31" modified="2022-08-03" version="1">MSYVGEYRDRLRDGKGSYVFPGGCFQYEGSWKRGKMDGTGVFTLPDGGTYEGDFVNGEIEGIGLRRWVDGSTYNGQFHFGERHGEGVYIAAFGEIYEGHWQENQRQGLGELKYPNGDIYRGEFHQHYPHGDGRLIFAHDGEVYDGNWVKGQRTGKGVLENAKGKVLYDGEWVNDQREGYGKGVCTTQAQIDAAAILFEGQWTTNHPIAPTDRLQFKLHPEIASGDAPCQRELQNVPDAIQVEKKNGLRLPPLAVVSIHDGSQDNESIMVSGESGRRLRIRIFEGQIPTQETISTLGDDELSSSTPQWQFAIPRPMDQEQDRVDEPTEENPELATEEPRVSEFVVENQCGVAAFHELVLPESSLIGGYYLICESLADDVLPPVYLAVTVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS21</accession>
    <name>A0A8K1CS21_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007595</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="721"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="776"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="845"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="871"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="951"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="90"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="411"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="735"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1306" mass="144725" checksum="0EB3017AF1A6349C" modified="2022-08-03" version="1">MTKYATFDAGPRDAPTLHPYDTASWLSRTMLSWVTPLMTLGNHKQLDPEDIWPLQYSHQAGELVKTFSKDYDASKSLVRAFFGSFGVRFLLTGFGSFAATAGTLVGPLVLNKVVTELTTDTYNVQVLTTWIVGLFVTQVVQALAETHSNLGAEVMSIQLTASLKNLIFAKSLRLNADSRREKTATEITNLYTTDCEFISECAIYIHQAWIIPLQILSVAVLLYRFLGVASIAGFAVIAVALFANHFVSTRFLTLYAAFMQLKDARMQALTEAFKSINIVKFNAWEDKCLQRIGEARTNELENVWSALKLIAGSVVILWGVPVLVSVATFSVYVGVLHETLTPATVFTSIALFQLIQNPLRDVADIVASIGKAHVAQKRIAAFLEMSEIDTDNVHSIQHPDANQFIKQNIIVAIQNATFAWDNDTPILKNVNLNVHAGDFLVIHGPVGCGKSSLCAALLGDMNKTSGGVYVGGSVAYCSQQAWIQHMTVRDNILFGRPYDRKKYEKVLEACALTKDLQSLPAGDRTEIGERGVNLSGGQKARVALARACYSDASVFILDAPLSAVDAIVQNEIFEKCLLGLLRHRTIILVTHNPEIIASEHVTSAVTLNDKGELVETRKVKHPSRPQYDSAITPLALLAYTRPSYDDEIHHQHEEHHHLAESDLNVLDMAKEVTTPSSRRGVEVNSRRPSFVEADEADEADETHVLVQAEERSQGRVGLHVFVSYYHAIGGFPVLFIVITSQVLWQVLQVSSDLWLSQWTTRSSSPEGDTMSQSSRIGIYAALGLSSALMVVVRMLTLSWFGIGAAKRLFDRMVYSLMHAPMKFFDANPIGRIIARFSNDVTDVDMMVPLVFGSFFANLLVLSFTMGTTAVIIQWKGLLLIPVMIIYVQVGRFYLEPAREIKRVERTTSAPVLSHLSECVDGGAVIRAFGTDQVLRFHFANDSKLDSANKVVYARLCVAMWFSLRIQLLGSLLAFISSYSLVLLHKELSPAIVGLAFSYVLKFSYSMERIVKTWSSVETTMVSPERMQQYIDIEQEAPHKIPTFDPPASTAWPSAGAIQFENVSFRYKDADQLVLKNLSFFIQGGEKIGIVGRTGAGKSSLTMALFRINELAGGSVLIDDVDVGKIGLKTLREKLSIIPQNPVLFKGPLRRYLDPFDEYTDDALWNALRRVGLIDRITSEDDKLECMVEENGENFSVGERQMLCMCRALLRESRIVIFDEATAAIDHETDQKLQRVIREAFVGSTVLTIAHRLDTILDADRILVLDGGEVVSFACPSELVSAGSGHFYDLMREGGYLDKFRTRGTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS38</accession>
    <name>A0A8K1CS38_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phosphofructokinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_006279</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS38"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000002">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000018">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005301">
        <property type="entry name" value="PRK06830.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="14">
        <location>
            <begin position="136"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW68811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="512" mass="55912" checksum="B70EB4E5B6A3A800" modified="2022-08-03" version="1">MSSQKTTSSPPPAPLSPEAAYKAQHAHAPFFDKHPQGFGDMTLLEEVQITRTYVLPVPHLAEWLPEFDHGVANRRKIDTKASDEVERKDTYNKIMGKTDVILGDIRRNATQEAVSRAYVRAGPRSALYFDPAKVKAAIVTCGGLCPGLNNVVRDITLSLWNLYGVREIFGIRMGFAGFYNWTSMDQKEAPLLLTPRVVETIHHSGGTILGSNRGGFDIDKILNFLTKNGVNQLYVLGGDGTHRAANKIADECRARRLPISVAGVPKTIDNDVDLLDRSFGFNTAVEEAQRAIRSAKTEARCVPNGIGIVKLMGRSAGFIAAHATLSSGDVNLCLIPEIPIELSGPRGCLEHLERVVEEKSHAVVVVAEGAGEELLGTSTIVDAGGNKKLPPIGEFMKHQVEEHFKRKGKEVTVKYIDPSYMIRSVPANAADSLYCMMLSQNAVHGAMAGYTGFTVGLSANRVVYFPITAITKNSPRCMDPHGRTWERVLCVTRQPNTAPDEKPKVRGAELCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSZ9</accession>
    <name>A0A8K1CSZ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSZ9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="106" mass="11362" checksum="D8D48084AA58BF2F" modified="2022-08-03" version="1">MSISLDSDSSGFSYVWFNNSDCSDISVGNNFMFPRDFNTSADGKMIPSVIIDNASIVVNITNTVNAKSTNFTISQCDTTSVTFNTGFLTAITPTVGKLIVIQGQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTJ0</accession>
    <name>A0A8K1CTJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type ATPase A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTJ0"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P-type ATPase A" evidence="3">
        <location>
            <begin position="103"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="825" mass="89543" checksum="2670E1A588880F8D" modified="2022-08-03" version="1">MMEEETEFDSHASMAAMSVLPLSLSQSLLQNASLRMTPLSPSHGDRFKLYDEHFVAVDELERRFETNRLSGLLTHVVARLQSESPRLNLLPTDVEVGHGSIHELVAVLRDGSWIHTRAENLLPGDVISLKEGQCVPADVRLIECDGMWVDQSSLLGKRQHEPRDASTTSVFDAAEATTPYLEATNMAFYGTVVTKGSGKAIVIRTGEDTVIGGISTRLLEIKRSTNKRLDIPMTESMKQLEVFCKGDSLPSAINRVSALVVEHSDVVKRSIISSSFGVNPPVVIELEDAVLANEMSTDDLEREITLQMMTYSQTDGDARLFTKALAACRHRIDGSTLPSSSSSSGFSSTERVPSLPASSPIAAPVVIDPLRDQNTILRFSAYFGMGSPKNSMYKKTRCSTLLHGHISGCEVYVHFDQDQGAYVVLLQGSAREILSRCGKVRRNDSIVSMETSDLLQIQAMVQDLEMRGQTIVSFAELYLDPSMYPVGVKFDIENFNFPTSNMCYLGSLGLIEKIQPEIMLMGSFARSADVRLLVAATDRMYPREETVSAISEDDDPGIDDKFMDSERTGVKPICRIPIKLREAATGEIADLSASAYRSSALSISNTLGQWEEILLGHQIVIFDACDSSHIDLLVEILQELGDCVGLVASGSANALAIANADVGFSVTSHDFVDLGEEAADVVLASSTCPRSDAIRLIEMAKKVPRRDGSYSQESPNLSKVMSTMTNLFRESISVGRMLGLSENELKSAFENALFEGNSTISSTPAPHKPISTPNPLFLPPSPSKFPANAFRSSQLLSTNPKVGAAALSAGVTGVGHLAATQLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTS1</accession>
    <name>A0A8K1CTS1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTS1"/>
    <dbReference type="OrthoDB" id="182695at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="644" mass="72699" checksum="9C3BAADCC941C7DE" modified="2022-08-03" version="1">MPAGGKRKRLEVEPPEDEAGADFVSSASERLLSEADAWRIALTWQKQLHQRVGLVVSAVPERLSRNYNCVQFDFYEESNKGIAKDLPYYRAAAITWFALSSCRGYSGRENPLFWRRVFGALGAPYPNKSNSHAFHWRDDFVESVRDTTRFFDDDVEIFPRYRLPCRTVYDSEKLCRAFIFGSNYDVVKAELSEILDELSPYIVPDRVDRAIPVVLYTWLYSSVPSELVKLLSLTKSEPSNSWRSPRFAVDEITNLDGRRYGSSDEMKALFYNYPIKVRNTPLLEVETKLDSVQITAAGVRILEVMAKGNNLRNVLFGQPSQNTAYHSAKLLEDAVIYREPSVEAEVLMSGMVPFLSVDVSLTVDESAVDALPDWVCVIIPTYGHGWTRAFNILSIKSREPSPPLLKSLVVGCSGLSPREVLPQLISVIGRNLRFLDVAQMETSDVDTLDSVLRLCPFLESLNVHHDGAMWAQPSCAKKERPKLRELGLKLPHNGRVSSRYIPPSDDIAKTALRELECFQVCAYRSADFTSNSAAFKATLQRIPALQHFQFDLDSIPSRRANRERAYHQAHEYSWQMMGIEKDSPDAFALGNKCSLPTRMAFLSVVKQLGSARNSVLQYFGSDVVENVLSYVPTMKPRTISITNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUC7</accession>
    <name>A0A8K1CUC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUC7"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28080" checksum="9C1812AC0719973D" modified="2022-08-03" version="1">MAAVYNNSNNNLKRVVLVTGGNTGIGLATCKDLIQRDNTHVLLTERNQERVNAAVKQIRPAAAVTSSIEGAVLDLGYLNQVRDYCDQLKKLDVTVDSIVCNAAIAIPTPDLTEQGYGLMFTVNHLGHFLLVNKLRDVTKRVIVVTSETHDPAVVPGMGLSVEEIDDLVYARGKMGTGFAYPVGKLCNVLFMHEMLRRNMDKSEEVERVCAMGVYNNTSEAAGQFLAGLSAGDWATAGWTSGMYFVSHKPSEPSQGSKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV77</accession>
    <name>A0A8K1CV77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV77"/>
    <dbReference type="OrthoDB" id="5560686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051760">
        <property type="entry name" value="KMT5A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167:SF1">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="22"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="152" mass="17166" checksum="8ECEBFBC9392FC3E" modified="2022-08-03" version="1">MSSSVEGVVTTTGSDGARAVQDGVEMRPSLIPGAGMGLFATRAHKRGDVVCEYVGTIFPNKVAWKRTDKAYLMKLGEGKYVDALEHPEVLARYINDCRRRAEYNVVFDKRPSEDRALVIALRDIGVDEELYVDYGRFYWIAYNLLHPEHPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVM1</accession>
    <name>A0A8K1CVM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001924</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVM1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="378"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="478"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="571"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="601"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="634"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="667"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="700"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="90363" checksum="FBAD9A056ADD0FDC" modified="2022-08-03" version="1">MTLQSTEKHAFITAAPEGRLDDVKELLNGGVDLFVTTPLDGQTALYAAAAGHADVVRFLLSKGVDGGHIEALNCETQRAVDLVLSSRHVDVLKAFTEFGDLGTALVETSAAGDVQGVELLLQLGLDANAVNWDSALCRAAQGGHEAVAKALLEHGPGVNLKSGRLLLNHGADVNVPGQWQWTSLHQAAQGGHVDVVDALLAGGADVNAVSQMGTTALYEASRIGHVATVKVLLDRGATVHPLNSQNPMNAAAFCGSVEVLELLHTRGFLLNATSADMTTPLHEASENGHVVAVEWLLARGANADAVDSNGKNPLHFAACKGHGDVAELLLAHGIQVDARDTCGGWTALHEVCVARPEADEVVLQLLNYGFNASLPDMYSHTPLLLACTVGNGKIATMLLDRVTDIDVVSQNGTTALFYACGAKNLIDVVRSLLGRGADPLCVSAREQTLLHTACEHGNAEVVQLLLDRGINVNALDRINKTALQYAVSKGSADAVKLLLQHGADTQLVDNINYTAFRYACGFGYVDVVNEFLKYEPYSEEKEEYFNGALSEACTSSRLEVAELLIEHGVKASHAALQSASRSGQVELVQLLLAHNVDPNESPDSPLHYAALSGEHEVVKLLLVNGANVHARDSHNYTALHSACRWDSQKAAAVLLEYGVDIDAVDKDGSTALHIAASNGNVSCVELLLKHGADSSIADVSGWTALHHACRRIRPAVVRVLVSNGADVATKNPDGEIPLHIAAASHGHAGNTPLDCCLQTGSYESYPDMTYKVAYELVKHGATYEESSDNCQSMGEDSRDQFSALELVVQCWVAERQENKPFTAVPVDVIIKGRAATEMYLEKLRTADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVN6</accession>
    <name>A0A8K1CVN6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVN6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="198" mass="21991" checksum="8B36FE730609DE7B" modified="2022-08-03" version="1">MPTTTTTTTRTISPSGVDRTVAWTAYADFDQSEKENIGYVVRRPSRVVTASSATEDSVEAAPVRPRKNGKRRLSEILRTSAERDEDEDNEEEAESAPSTAPSSGKGKKKLKRSRSLPLTEKETASLRAMQAKTQTKTTKTMTQGEAKPAPSPPVAPRRARRPLEDITHLFVPPNAHQLQPWSRASRWNPPSSNPLRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW02</accession>
    <name>A0A8K1CW02_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW02"/>
    <dbReference type="OrthoDB" id="89365at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="113" mass="12840" checksum="3515117E2D1539BB" modified="2022-08-03" version="1">MSQDTENSDSNSPLCLYPSKPCSNPRAVKTSGELHNLCEQHRRRANVNQQKLKFRQRLQRLREMQELLDAEAKSLAEQQPEMTAVMKVAAAPDEQEADLTDAEIAMLLQMLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9Q5</accession>
    <name>A0A8K1F9Q5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U6 snRNA-associated Sm-like protein LSm2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010352</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9Q5"/>
    <dbReference type="OrthoDB" id="10256176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01725">
        <property type="entry name" value="LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000009">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016654">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829">
        <property type="entry name" value="SNRNP CORE PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829:SF2">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016394">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="96" mass="10761" checksum="C18D74D5F1F41F0F" modified="2022-08-03" version="1">MLFYSFFKTLIGKQVAVELKNDVALVGTLHSVDQYLNIKLLNVSVVDGDKFPQLMNMKNCFVRGSVIRYVQIPGGEVDTELLQDAARREAKANKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC14</accession>
    <name>A0A8K1FC14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC14"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="249"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="449" mass="52172" checksum="112B0255F85EB5BE" modified="2022-08-03" version="1">MSDEEDYEFDYSDEDEEMEDGDVDLQVQIQNQYYNAKAHLEESDAASRDAALAALEEVVEMQNESQSDWGFKALKRIVKLHFELNRYDAAIKRYEELLGYTKSAVTRNVGEKGINSILDFVSTSKNWEILQRFYETTLETLKEARNERLWFKTNLKLGNLLYEIGDFTRLTKIVRELIASCEEEDSEDGVKKNSQLLEVYALQIQMYTSQKDNKKLVSIYEKALRTKSGVAHPKIMGVIHECGGKMYLMQREWEKARVDFFESFKNYDEAGEPRRLQCLKYLVLANMLSESKVSVFDSQEAKPYENDKEILAMTQLTDAFLHDEIKTFEKVLNRHQASIMADPFIKHYIDQLLHTIRSKVLLKIVKPYRRMDTRYIARELNGISVEEVESLLSSLILDQKIDARIDQLQHTLVLTGHKAEAKFQQSVVSWCDSLEKFHALTVDRVTVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC71</accession>
    <name>A0A8K1FC71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC71"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="162" mass="18392" checksum="4F07346E6FBDD3D3" modified="2022-08-03" version="1">MRTVFCLVLGVNDVFDLGFPDHAMTAELKYRLGDSVISTARIVVPAHTLKVYVVKADDGIIGLDPDHPDYAQLKQGNSEIEAKYMKDEMLLDSTHSIGHYFRGSRERAIHVLVKPIFRHGMGWTIHPDYAFLSLNATEPLILSSFRRPSENDVNRSKRLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDG7</accession>
    <name>A0A8K1FDG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IQ calmodulin-binding motif family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDG7"/>
    <dbReference type="OrthoDB" id="10253073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504:SF2">
        <property type="entry name" value="PROTEIN MFI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="56307" checksum="5BD51726E747CA73" modified="2022-08-03" version="1">MERARRLRAIGFRRGRYQSKFVARLAPKTRHVRSIQPGMVWESLFMRKSRVEKRAIVQKPWEFPMAAQHLAAILIQKRVRGMLYRLHIHQDNQWRPPQLCRATSSRRHFASPMQRFIHSTNGTFDDDQGFRHYAATLIQAWYRKEQLRWRYTRQRFALYHIAALQIQYTWKTHYQRRLYRKHHPSRLGGASLSPRARAALTIQAAWKAYTNRRIYRYYRDLITFRNTGDPAMMLRAINPSEAGLLDAAMGAHVRFRLGGMSFPPTIYYKIFTRKAVCDLNAFSPKDYTLTRRTVPPTSHSKPSQPHQRLYIRVGQSYYRARQTAEEQDRQHWYKRIENNGWRPVTAKVLSEANHDPIAQATGQKAMDRFHYSRLVRKQDIETQRRLRKRQWMHKLYTHGLLTDISPEATSLLHRAHSQEVFDVDFENEQWEAEAEEMFQWVSALDYDAYLDDWHELGKTASTDDDTRLIQPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDR7</accession>
    <name>A0A8K1FDR7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDR7"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="2">
        <location>
            <begin position="429"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56349" checksum="3119184036914AB4" modified="2022-08-03" version="1">MLAHESVKPAGVLRVEVLGARNLHAAVLGSLLKWTPSYSNPYVVVTLHQDEFQTSVKERALNPSWKETGELQVPLPTEQELLQSNGSGANAEHAKMNAMARKLTSSFTREREFHPCFPEMKIKVFHHSESPDGDHAGSVKLDDKLIGEVTVPVLPCIMSRSSSHRAWFTLTSDEHPEAGQIQLAMHYEVGGTEPMKGDIVRVAGFGGMDYYSKLFQANTRLEVVELYQDQVVCQCKSIEGWMLSFELHRNLLYVVRRPSILRDAHSQLQSQLSPVVRRAQSVWQYLPEGRRRQLLRLYQLATYSGNVVVDVVSESMDATKKYGLYAGLTSCVQGSGTAVKKVSSEVLRVYWKDPNARHPPTRSEELARYLEGGPLKARGRIVQAFGDAKVEDVVFLVPLAEGGDFEVEESKEDESDVEDELRRRSPLADCPEQLICPITGCPMMDPVVAADGHSYEREAIVQWFAASNISPMTGTKVPTTQVFPNFTLRKLSEEFQRTRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDR8</accession>
    <name>A0A8K1FDR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDR8"/>
    <dbReference type="OrthoDB" id="429067at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="826"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="967"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="721"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="548"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1060" mass="123082" checksum="0599DC406D0A48DB" modified="2022-08-03" version="1">MEEAIMENEEAVFDMNTIHEETGDEHAVSEAPEPTAVAVEERVASARTQLMRPLTTERGEMSDWIECVNEEGDVYYCNLTTGATTWEPPFPLATVPAQHHGASLPHTQSSHEEVDGDQHQPSLRLVKRALDGSLRRLDPHAQMQLEEARRRHRELEELRDDEVLMGGEHWIEMYDPTHDGFYFYGINSGEMRWDRPDSYVMKVENDDILRMVVRLQCAFRMKLARRKVFRMKVQHGLASGENTPFSSPWVEVYDPFHRVLYYYSATTGETRWDPPEHFISAAEDREMAAAIAIQSMSRSHMARRDVKRRRTALFKIRQEKAAEETRRLREIRRREYLAKTDEERESICRREMLDEEMEQVQEGDLFWGVDKHDQEVLRQQMEERLLYDAECFWHRVNVTLRQRTEQERQRNLEEDTERRELELLAEARERDGMSAAEQEQCSLNDCFWGIQAEEWRQIKARQDLADEEEQSREYAAQAQIEGLQYEWAESAERLTEWTKRNAVVQEKKNQRQYFKWFYHQCTSADQLLDYLWPNKQRYVPPSPVKDAPQSTQKPQPNTMSPAKTRVKKAAATDPPVSYVLDDIVLRSRLIDGYRFDGKSLLTVHDPSNARIEGRRGQYVVSHLDTERVYAAAAAKADKVPRNTLPRRPVPASSKRKPPRIDVDEASEEEERSYSHLHYQRPMTPDPHLPARYNGVPFRSSELSPTREILLSDHSKLTQLPSLAIKPKALQKPQKRSVSPTHQSNNQKPKKLSLVGKALRDSNRLTEEAIYTTLAFASPFARQNPKVKLSVAIPETEEEAPEERARRKAEEKAKRVRDKLSRQFQHEELEVVRHVFELMDADDSGTVNKKEMMWALQRDNEVHSLAKRSLLLRVLLKQQAPLETLFEHVRKADGRGEEVTWVVFQRFCEEVYIRLKEQGLLEALVGEPRQDKSSIKKKKKARVKAKAVTKGLRAPEPKKPAVRYVEEREEALIRRVFELCDRDGNGVLDMNELQDALYTSPLEEIQALVRASTALQPLLQQDLFIKAFKAYEPADRRGISASEFVVFCLEVAEIAVLNGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF32</accession>
    <name>A0A8K1FF32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIH1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF32"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="3">
        <location>
            <begin position="99"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="597" mass="67057" checksum="779044A4AFCFE589" modified="2022-08-03" version="1">MATPEAEMEEYAKLLDELYAKDPQAYEQFVQMMKQQVEAAGAATEAPSPQLNSAASTPSMLDMIKNAATEGASAPKKEEFKPQFPGNKVMASDGLSAKQEGMYIDVEPGFVMKTTDIHKKRKVFVNFCFSDVIQTFSQRKQLDEEGKEQEGIHVPLSLGAPREVKDKRGDTALAFDVAVNTQVIEDSKTDKTGSFRNFVCELAIEYIDQKYQVKLDSRYKLPKLTYRGELPPPKHYIRKTQKPIIQEVDGSKKATKSATTKAVAVETPAKTATLQHELFDVVGDTRKPCTRVPAVDLNGSALSEEVLRSAGTHLLVLFRFETAVASADDVELELRPEYLTVKVTGHQDLSLFLPYPVQVATTTVVLDRTKNTMEIRLAIDKSWGLNEPDVGSAPWLLTQALRDEDSDKKDTVDTKRKEEEPKSLVDMFHLAMPKTEGSDASSTTPSTQEHTARWDPVDEDDELPEDRFHRRDMMSMHILEQRKKERQLKAQEAEEKRKTKRAEVEAKQKAAQEAGKTWREMYPNEPETTYIDMEDIIAREKEKKKKQTDDEQTSPNESNAKTCVPSDSAVQVAAAWSEEKKTQGLDLNAALAFDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFS2</accession>
    <name>A0A8K1FFS2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable pectate lyase F</fullName>
            <ecNumber evidence="4">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004348</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFS2"/>
    <dbReference type="OrthoDB" id="168235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="277"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="13">
        <location>
            <begin position="335"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="1063"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW59279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1091" mass="124517" checksum="515F377A7723FAE2" modified="2022-08-03" version="1">MILSLLRRREESVIFAQQSIQVCIQHYTDAMILSSFFGDYDEQVKSRFGKGKKGERNQHQAGFPILPFIYLMVAGLKDSSKWEDTDVRDLLSVKMERSKMIALFKAVNQHASNVSKSPSKSKSSSPSKKKKPTEMFSTTEVDLAMAKSAGSTKRPLIFDEFREALQSLADLKMNHVTIWWSRFEGPEARVLAMLWQYVFVVTDVKPLAALLAAHASSVVHERAKAIQRLMLKGRDKAQGHLIRLQMLSEREMELKRNAITRVQCRIRVLLAKKQYKLKLQAQYEKYIDPDWMLPYWMNPRTGYSTWLKPRVLEDDDVSSEAIPFPTPALTLSMDCQGERECKTCSDIYCYECDDAFCNKCVAQRFHKQDKADHEVEVLQKCGLCKFQIASRKCIDCKAMKEARGGKRNGGKARQDKDKFDSDVAAAPEDDVLFCDVCFAFTHKRGALQVHKSLPLLEMCVDCLDDDEALDHEKAPPVKPFAKAAQWQCNTCFNRRICSSCATTKHPVEACGELERVSLVTMTMKQRADRIAREIAEKERADVERMKRLILEAKRERYVKKIQKFWRNQAPLLRARRIARQLRGEKDAHWQQIQQDAKTQKEFKYRAKNLVGFAPPLPTDSPVQQKLREMNALQRRQLSIRARMFGLLISEYMVLGVPLPGIARVGRGQHFIECTEDLRGWLLNRQTIRLKKLPKVKRRQKELADEPLPDFVWRHDLEKWMRDPSDTILVDIHSKEKLTERQVPLSIGFLVEPKKDGPAVAPKANKDEDEELDVEEYALFLVEYSMDPKRVVWINHSFAEQFAAWRRQKFHAYRERQAQMKAEALEKLQEAKKNEQKESPTQAPLVVDTAPVVAAATEDTTASSTWPTAAYAPETPATSSSAYYDYSGYYSQQTSWPTSSWASSPYGYDYSNAGFSGYDSTGATTVTDPSIPQLEASNEYFYADDGNAAAWEAYYQANPSATTEYFAGWNTGAEESYPYTGDYYNTETETAYQQYDATYQQQSTYEVQPSSAAYATDAYPASNYATAYDPYSETSAAYYAAGSYSTAGYEGYTTAASAATASWPWEEVFDPSTNHAYYYNHETQETSWQVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG09</accession>
    <name>A0A8K1FG09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG09"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="22436" checksum="7D49C8354756E0C4" modified="2022-08-03" version="1">MPLYKQVLVTNLKSTPRDVAKVFQECAKLITAEGGVIRTVENRGEKRLGYAIEDRRWGELQRHYEGKLVVTQFNTSPATLQDVEAHLKNAFPIIRFQTFKVRDPIDSLMNTKQPLEALKAALTPLKQDARLKIVQDKKKAAAEKRARRDAQFFRPESMFETEEEDDIERFKQYVPDWKRDATFHPSPPEHLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG12</accession>
    <name>A0A8K1FG12_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG12"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="596" mass="66811" checksum="67A3AB2976325601" modified="2022-08-03" version="1">MDRRTDPTLCGQTRHVFLHYGRVQVYPELPAHLPPTETAAHHSTTLPAQRTRRIMKILSIKNRCDSRLYFVFCTVSPCKCALCANWLAQEKTPIVDWRRATYGFLQIEAYGERIDRFCDQWRCIGGCFFDSLPTIMKKDMLVEFEEDKNYKIGGGRAKVRFSPSSDADSTPSSKSSVASTPTYKASVQSTPKAPPMTPLKYLAVRNFSDATFYFVYCTVSPCKCATCQTWLKSEQRGIADWGRATYGFLQVKPYGGHVARICEEWKCLGACFFRGIPSIIKKDMLVEYADEQNYVIDNGGAKLRFTHKPQVFDKAKYVHIQNHSESMIYFAFCTNSPCKCHVCEQWIKAETTPVLNWGRATYGYLPVEPLGQRIDRFCDLWSCTGACFFDQLPQKMEKEMLFDFGSTTNFDFGDGRATLRITDKPDPSVRTNYVHVQNLSDSVLFFAFCTVSRCKCAVCLQWLAAEKIEVTNTQGWTVGRFVVGPNQAHSVRICPLWECMGTCFLDGWPKEINKSMLVSFEQGRSYKIAGGRARLSFATAKSNANVSNQLDADLAMFGAAAVMAPGLEVALGIGTDLAAEVAGNLIDMAVNGCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGM3</accession>
    <name>A0A8K1FGM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ryanodine receptor Ryr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGM3"/>
    <dbReference type="OrthoDB" id="300855at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034704">
        <property type="term" value="C:calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005790">
        <property type="term" value="C:smooth endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005219">
        <property type="term" value="F:ryanodine-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014808">
        <property type="term" value="P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006941">
        <property type="term" value="P:striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015925">
        <property type="entry name" value="Ryanodine_IP3_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003032">
        <property type="entry name" value="Ryanodine_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399">
        <property type="entry name" value="B30.2/SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399:SF8">
        <property type="entry name" value="B30.2_SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02026">
        <property type="entry name" value="RyR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ryanodine receptor Ryr" evidence="2">
        <location>
            <begin position="74"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="255" mass="29057" checksum="0771AF336434CE5A" modified="2022-08-03" version="1">MDEQQYDYRMLDETIRTTLFLNYSIKPKSTSKSTRRRDAAKSPVSTSTQKPPPDPWSSSQLYSTAYGENLDQVYRPSPVDTSTIELPLRLKHLVDLLAENSHGAWARGRMDENWTYGDERNDRAKMHPSLVPYLFLTDEERQYDADVAKETLKILLALDYKLARRSARYKQTVIMIMESITRTLRLDVNALDSQQSLEAQCHCPSPDESWLACPFNPAPVLQRDVHGCQASTSALVDRFLVFSCLGSVITELSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGX9</accession>
    <name>A0A8K1FGX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGX9"/>
    <dbReference type="OrthoDB" id="94615at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="64226" checksum="5B775B1D687066E0" modified="2022-08-03" version="1">MKFPVVEHPFPPVRLTPEQCHEYERVTTAMLEEAVEEYNRFVHVENRKLDKKKWKAVKSRENLTVYKQVEREFGSLLPTHASAKMNSASRTGMDDATAYAASTVVTNVHEWRLPRLLGVGTIAGMLDDVMYGFITTDLKSTLLRASYLKDEIVDGRVLNQIKGPTPEDPFRFLGIKWVVKAHMSGINTVVLPRDCLMILSTGMHTAPNGDRFGYHVMQSVELPECPELKSLSMRRGGMSSCYLFKQAKNGSVEVFLKSYAEPGGHMPDSVATLSISNSLIGCWKSVWCAQGKKIMWMIKKRAAERLERRRRGLKTGEEEAKTSKGKKYSCGLCRDSFRAFRSTNCCDICMRLVCSRCHMSRKVHFIQRGYEVKDVSVMVCKTCTIESTQLDAFELAREEAFRNNGSPNADVYIEEEDWMINSNGPVDPSSRSSDSSSSDVAVTDLLQGFTSSVSSYGTSVSSTGSLSYGTSVSSSRRPSDPVTLLERSSNTRSMSVDSDYFQGMEPQSISPINSIASPRWDAPTVEEPQSEEEYRKHLWMQMQQLRLAAEHTYMITKQTASVMGSSPPSRSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH47</accession>
    <name>A0A8K1FH47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH47"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57526" checksum="14C1B6BCF88293FE" modified="2022-08-03" version="1">MLALPPTGLSTAIWTTFAVVGAFVVLRRLRRETKLPEGVQIPLELPGKLPVLGHTHFFAKNEHVLNDWLASQCIKYNGQPWRATIMGQPEMLVLSTPEAMEDVCKTHFDNFPKGAVQTDALNDLFGDGMLAVDGEKWYYQRKIARNLITMRALRDSMSAIVQKHTKTMVEILGMAADTQETLDIVRLFRELTIEAFAEIAFGIEMGSLGTEHEDPFHTAMDTISPLLVLRFRVPTWFWKLQRALGVGAEGELARNIKIVDDILLDVIQRSLASRVDKTPSPDSDSKTHDIISLFLDHGEEQLTAKTLRDIVLVFLVAGRDTSADSLSWFWYLLQKHPHVEQAIRDELDAKLANNDSLMSMAQVNELVYLEAALRETLRLYPAAAFVNREAACDTVLSDGTFVRKGMRIGLSSYALGRLPSVWGEDAAEFRPERWIDPETKTIIQVSPFKFMAFHAGPRMCMGATLAMLQMKIIAAKVLTRFHVDVLPDQDMTQEIGLTLAIKNGLRARVRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH55</accession>
    <name>A0A8K1FH55_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH55"/>
    <dbReference type="OrthoDB" id="160530at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="19332" checksum="14B5F7682457A3B1" modified="2022-08-03" version="1">MGKITNYMRVTKRRKVHEKHEKMVERVGKKVSPAPAIEKLTVSKTKPEENGRVITYDGDELYEDGHHVPRFIFNTVKYVRRGEAHEVPMTTQKIVDYIREHYVIPIDFEQNHKYGPHSGMTYEERLLRAYKFRLLDLKDSDLAEPEVICVSCAVLGHSDKECPDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FID1</accession>
    <name>A0A8K1FID1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FID1"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF105">
        <property type="entry name" value="F-BOX_LRR-REPEAT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="1">
        <location>
            <begin position="186"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47040" checksum="267CDF011E5A1A83" modified="2022-08-03" version="1">MGMATIAVAASRVRCESEVVDGEKQRKVLRLHAPVAPEDIKTWDKDAPRGKDGLDQVTSEALQQILDFLPVQDRFAVLTTRRGLLQDTALATTFTSYCGECSDCDAKQQHLCKNGDNNRPGSFWRTLLRYSGASGLRELHLASCDGFSAELLSGMDPRDRQRALEGLQVLDLNRCTALGPQGLLLIAESCRNLRQVHFRDMPIDHAAFERLVANNKSSLRVVNLLGCHTMTGEDVGLLSTCPELRDLNLQGCHMVDNAAVADLVRTCGNLERLNLRYCHKVDDALVKIIASSAKKLRDLNLRYCYKVTDASVTAICEGLLKLETLNLSQCNKITDAAIGRIVATLRSLKELRLWGCAKLTSASVIAISEGLPSLVLVDIRSRDKLEAVIGGPVALKCLIQTYRDTLARWEQAEEVGVFKRLPVCAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIT6</accession>
    <name>A0A8K1FIT6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIT6"/>
    <dbReference type="OrthoDB" id="163632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="549" mass="62722" checksum="471AAC5A4AEABAC0" modified="2022-08-03" version="1">MSSWKDKLRTAILLHPMEVELVVELPLQTFQAYRMSTLVSTVWINRLLASVIILNCWFSPFVHLVMRKYSAITRQLVCVAMDSLLDIVYGIFIPLAIFYPYWRDYDLTLYSFPFILYYRDEWFINAIAENQQLFVTSWMDFAATMSPGISLFVRLYEIQRILTAYRRSRAVHVPSRVLLGNAGRHVSTRLIAVASSEPKTLYARRSLHALLVLWGLVVAMLHLHSTVVAVRGADTGCIVEMRPWGSNKYTCTVFEVSCSQKHIMGRLDEMDKQFAVVNPDTLQGLVMSNCPVLEVPPRIQEFKRLLQLKIYNSTVIEWGREAGLTATLHPELQVMFMLEVNFTEFPMGLRWDEPLPVFFDFELSGTNLTSVPDEMEKAWGLLQILSIERAPGFTQVPPFVSRLSLLYMLLLASDNIVSIPDDLLKDSNLMYCMFNNNPVEEIPANVGNLAGMTWLGFPWTKVKEIPASWQQKETTPGAEGLPDSKTVELHLFDSPYCGALQDSLTPTPWLNGDLMMGWFETFCHEDGAAAVPYFYPVEAEHEWRARNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJB3</accession>
    <name>A0A8K1FJB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJB3"/>
    <dbReference type="OrthoDB" id="57748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="45"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="30000" checksum="569019E1DD617A3C" modified="2022-08-03" version="1">MTSMTTRVRLYLALLWWQLCQWVVRFVYVNSLAPSSQFFHKVVIIGDDFAAGLGDYVTMTSSAGLARHLKGVIAGNDKVRHRWEIINAGIPGSFSQDWLLNAPTKYFESVFSSNKRTSDAEIVIVMLGSNESRAKSGENAKEISRNLMSICDTLRKKGKHVCLATVASSTPLEPTVEKIPLNSMLEDFCASTKGDDMPVILGPRLDTYAFRRDNVLSFDGYHFNSSAYKLLARNTADFLVPMMTAVEWRTWKDQLQKVTYDKSLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJE1</accession>
    <name>A0A8K1FJE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-type lectin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJE1"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457246" description="L-type lectin-like domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="312"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="46001" checksum="A4C210715DB839AB" modified="2022-08-03" version="1">MRFLIALACVLAACVQLTLAELLTSLSFNKPFDTISADGEREVSKDWTHGGSTAVNRHFVRLTPDRQSRKGYIWSKEKLGRREFSLVLTFRISGQAQTWFGDGLALWITTSPSYVAGDNHGFTGNFKGFGFVFDTFVNQEHSGGHMDVTFLENNGSRTLDDLYYMPKVGCMAPGIRYHEGNAAFSPSLNMSRAKVQFANHFVTISIDAKNTGEWEECYRTELLIPEHWIEESTIGLTASTGGLADNHDVISVQVFDEISDAGHNDSDEKVRGLTEHLDEATSSVDNEARLRMLKRKYQQLVEDFEHQFTALKESTENTIKKLREQEAEDTARIQDLELWAEGKVAESVYRSVSEVREEVEDKLKKTVEETAKKTGSWKTPFFVLVLVLGGLCAVGYKKYQDLRKSHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJH6</accession>
    <name>A0A8K1FJH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_000790</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJH6"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW60748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="342" mass="38823" checksum="001372F955B90B12" modified="2022-08-03" version="1">MRCGTIVKGPHKRPPNAFDHRHDTLNMGEKDTRVGGKQTTWPKCVAAGIAALAVCIGLKQSVLATFAWTLLAFYLPSYLDGAEHTGERYWPAYADFCRSNITHGFPMTMECEEEIDPAKQYLFASHPHGILSAHHGVMMTGGSKPSFHDISPMDTRNHLGASVIFRIPIYREYLLWIGCVDASRATAERVLKKGKSLVILVGGIAEQMVSQVKDHTVYVKKRKGHIRLAIKYGVPVVPAYVFGETDLYTHSSFLLKFRQWFAKTFQMALLVAYGDNKWLPWKPHKGVDLHQVFGKPVPVEKNEKPTQEQIDKVHQAYVDELVRVFNKYKEKYGYKDYELKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJY0</accession>
    <name>A0A8K1FJY0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJY0"/>
    <dbReference type="OrthoDB" id="114950at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="75" mass="8322" checksum="55540F707CE7A207" modified="2022-08-03" version="1">MEAYASPNHQYAQNQLRSFVSLEDDDEMTQLILEELAMPRRSSFVNVIATMAASPSSKSENGLNAIVEEDQSADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK11</accession>
    <name>A0A8K1FK11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK11"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="327"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="578" mass="65431" checksum="183B178C8C3F9725" modified="2022-08-03" version="1">MVWALLVSVLLLFSSIATFLTMLHLRFRWDVHVSSVRWLFWLFFLYLWLWTSTRTAYFLWLSTAPAQDLNQDVLGENDTEISDLDVLYALLQIREIQTTWLTVVFIAGDIALLGIATTLFPLVYELARIARTLMDRGAELERQQTNLYMWCIHGFLMAFGTTEVTIAAVNGGYSSATQQCLVLIYVVQFCGLAYMIGWVIKIKRNGRQFETIHGAFVKSPVYQRLKRIMTVYVLFSFQFQLASVIVYIADPSKYPAVLIYVGVSRLLYSASGLALSITTSCSQACVLTAFSHCLPDDFEAEFSQRRLGRSPTAPMDEDLEAPTNDPVFVFTDIESSSALWGIANGAIMSQATEIHDNILRSTLPKYRGYEITTCGDAFQLAFHRIRDAVEYCMDVQLQLLMAKWPKELHGAIPATQRRHFGHRRIFNGLRVRMGIHDASEIEGRLIQDVHAVTGKTMYTGASEVTAQFVGDLGSGGQILVTGRVAAWLKYRLDDLSVDFVVERVGFYTVPQVNLSVDVHQIQPLVLAERMRDFPTPEQGRTRQHQLRPIWWSFSQLSAPESPKSTPYVSIDMIGSRTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE6</accession>
    <name>A0A8K1FKE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_003736</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE6"/>
    <dbReference type="OrthoDB" id="193467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="121"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW65971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="340" mass="38142" checksum="969192DE4235C14F" modified="2022-08-03" version="1">MTTSTHGSHVTAISPAITTRNAVMLRRALQTASLAGLSAVTAGGIALYVDAPDGDRGDGQFDPTRRHDRCHEWLHDLGRVPLFALATGVSKVYLKYLSNTTVEGFENLHKHLEERPANTPLITVSNHTATVDDPAVFATILPWKYALPWYARWSLVSQEYSYTRGRLLRAFFFSAKALPIKRGAGINQPMLASLFEKVQQGNWVHIFPEGKIEQRMILGGRSGPRTKEIGRLKWGVGKLVARADVRPVVVPIYHTNMQKIMPQDEDNHIISMIPQFGANITIRVGKPISFDDLFEKHRDGRVVGSVAEWETQEREEALYSAITMRIEESLLDLARDIYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL81</accession>
    <name>A0A8K1FL81_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72741at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1274"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="733"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="903"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="980"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1198"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1232"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1295"/>
            <end position="1307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1343" mass="149275" checksum="46788DC646FAC380" modified="2022-08-03" version="1">MNATESGSMGMAQPHNTVVGTRFTTQAPSLVTERANATPLFAVYRELVNCVAVWGGGRLRSDAGPTAATAAQQRRSSAPTTPSDGDSRRHVLVDEALGNASSNTNETQTTQTRDGPRRRDAVAMTSVVRGNDGVSVAAPTPSWIEAEMEAFFDVALARAIQERETNLVNVMHECFQQQLGEQHRALDTQRQLTTSLSARVQSYEKEMTHMQSKIDRRVAENNALRKDFYKQLLMLRELVNKHKSDPRTLRALDEVITTITLGKEKAAAFAAEAANSNHGKRSADTRDQDGLRGDGSGVSQSNSLTVRREKEKWEERAREAMMECQQLQEQVLLLRQQIDEGGSEGSHWFSSAQFGLGERQRIIDAVYKGRCSWENVGDAVVELLNNDMIWEAVEDSAYREKTRVSRGFEAMLLRAEVSSEAVDDLDLDPDVDGVGGSSRRTLNRRRSAFSQGGRLVLCRSCNGCGYIDATAMQNGDDLPEENDSYLRKTLAQVLELKTALEKANQQTVQAEDALRKVVMEGSSIKERLERIEFIKAHGVDSGLQTGLDAEEEIDIDEIMSTYSSGESSGSGAMGSSRLARRNDGRWKQYEHLIVELKNSVTERDTGLAELRSTLSNFQSKLVAVQKDSQQEQVRHQQEVQTLKASLALAMKSRNDAIEEKQAAMKVMLKKMNTKSSKLSAALFSAKKVTESDASSDDDTQSQKSNNSSDNTDDVAKDECDDEADEVKRSELIARRYSDAISRVQQEYDEQQRALKQTEVQLTEETDKRKRTNSIMLGNIAVTMTSHPRDLFKALSTAHNELTNLRRSSQRSSALQTDRLLTLTTHLAHMSEELCMVRKRTNTEIEYWKLECEKLHNTNKMGSAIALHAPSGATGLPSHYRKKIVRKILSEQEVLQRQRARYSRSFSPPDSSALSTGASSFESYNPEVAENDGWAGYSTYVDDNGHVVHFVEVEIDDDPQSSQEMSLNPSAVPTTTNAMIANTTSTGYSGPHASNQSERRSELTIQIPQPMPLDTEDSPNQQETRLTTVARPTHSAAIDRDPQVIAQLRDLLNHISTTRQALALTNWRILLSHLRAQREERRLDYISHQFKQAVAAGKLGSSQSLPTSVRCTIQKLVQTRELALDTAIHDRDSLRRNVRRAQAHLIHGVSSILTTLSRKANGRVQVPEAPYIIHTDPQRSPPRNPPSPVYRGRPIYPTTPINLSEIPDTQQVPTPSFPFNPADGGGENVFYQKTPPVSASSSPAKSFVSSTLAVNNQLPSLFENDNRFPQRATTFVPAGDSEEKSLTHSTSTILHPSRSPASSPSKSSILLDARRRPTRSADLQWTKSIVYLNARLDHNRRQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLI0</accession>
    <name>A0A8K1FLI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tesmin/TSO1-like CXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLI0"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tesmin/TSO1-like CXC" evidence="2">
        <location>
            <begin position="438"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="679" mass="70374" checksum="89BA764C3EBA9A7B" modified="2022-08-03" version="1">MESSAPPADADEMQRMWQFLDSTLSSGSTPNGAPPSAPSAPVAQAAMPPAAATEAPPLTDDDNGMYNELGDVFNMFFHLDTDDAAAQHANGAVAAPSAGHLVDPNAKVQLPRTTSSGSSLSEGISPGLGYPSMSPATMNWLQSLANSASSESLTGLVSPATLTFGQSGSAGGLSVLDGSSSSGSAQGGLPRSPSCEMIDWKAYNETYGAAEKTQKEPPKWRVIPQHGPHADPSATAAASYPANKPPPASAPAALNEGVDDGGGGLRSQFITRPFQTIKSTVASIVGAALSGDVTAVTGAAQPVPHQHPQVDPASSNGVPPVVLPPEIQQQYELAAKRMAEDKNKRKAIISPEYVQYGTTSSGVTTSSELPMGSVPPPYVGGIPDPIKYEPSLSGSHPQQYATQVADPSGRRPSKKSLHHAGPLSPTGSTQSRDDTVPGGPVRCKCTGKCRNARCACVKAGFVCGVHCKCVSCANPFVPMEREGINIQTMVNDVCLMQYLSKVKDMQELLDSTVPYDCCDGVVQVKFTVEKGFTCPTCQAHYTYSWCSHRLCHDQKKPRKHCAKCRRCGDHRNEHCDDCNHCYFAGVANSFSCSCKTGGKGGSLGSGVKSRSVVASLAGSGDEAGPSMSPTSSTTSKTDTGGSASHEGNASSSSGNGGAKTMSEGLSSNEAEKDDACPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLI6</accession>
    <name>A0A8K1FLI6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014832</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000046">
        <property type="protein sequence ID" value="TMW63872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLI6"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="8">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="36491" checksum="061926B5E00191F9" modified="2022-08-03" version="1">MCSYYNYRLGQAQAGALEDDPRLSVLQQEWFQGKRGIDVGCNSGDVTIAIAKRFAPSYIMGVDVDPQLISRARGQLRDLVQKQQVEDAFRAIAADPSADSQDKSSATDSTKDTEAKLLPKDGSAEEAAATNVFTDEMPLSFRLWKPPQQPKHHTPQDLGKASRGDEFPFNVVFKREDIVNDKHVGTGYDFITWYAIELELAFLLALTAALVVLLQFQCDEVDSSSERDEGIQKAFRLFYDLLAPGGRLILEPQPWKSYHKRKFTSETTEVNYSKIQLRPKEFPTFLVETVGSSRVRSSRSARRQPKASSVPSIWLRSNCVAYSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLL0</accession>
    <name>A0A8K1FLL0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008011</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLL0"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="117" mass="12782" checksum="65940932D837B842" modified="2022-08-03" version="1">MPYIKVATNLPRASFDADSVLKAFSKSLSDALDRPEAAVMVQLEFGQDLILSGSTEPCAFVNVRSIGKIDTERNPKTYAALSATVLEQFKIPANRIFFNLDDINANNWGFDGKPVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLQ8</accession>
    <name>A0A8K1FLQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLQ8"/>
    <dbReference type="OrthoDB" id="157595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="210" mass="23243" checksum="C6F1E067CDC3EDD6" modified="2022-08-03" version="1">MQRGIQVTKKRHTVDGFEATVGTNHIGHFLLVKLLQDRVKRVISVCSETQDPAERTGLPPPNVTSLDELAKGYNKFNPQEAYTTSKLLNILHVKELARRSPEGPEVIAYTPGFTPGTSLTREHPKVLVPIVMAIMRLVFWCRSVRVSSIAYSGGHMASIAAADSLEAHGWHSGNYINIDRVMNPSSLACDPVLSKALWGKSEEWVRPFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMK4</accession>
    <name>A0A8K1FMK4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMK4"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045335">
        <property type="term" value="C:phagocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090385">
        <property type="term" value="P:phagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002860">
        <property type="entry name" value="Rab32/ GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF39">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="35282" checksum="887705C296437FF6" modified="2022-08-03" version="1">MASLLRGRASSISVDVVGAFSAQTKMHRRKGSLAGDEFQALVQQTQVEVLGKDTEPSQAEIDALVALYDGDSDEYSDVDSMDDDEYSDVGPEEVIFKVLVVGNARCGKTSTIRRFVSKQFSDHYVSTIGADFVEKVIDYDDSLRLHLQLWDIAGQDRFAKLTRAYFREAKGALIVCDITRANTIDAVETWKNELDVCCKDLNHGETIPVVMLANKSDLLQDPLSALNLGVNMQKSVTRNGIVEWFRASAKSGEHIDEAFQCLIEQMVQAHRQQKRDTKETHPLDDDSHDKSSVIRLSQYAPPASRATDSDNGGICECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNF9</accession>
    <name>A0A8K1FNF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sas10 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001502</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNF9"/>
    <dbReference type="OrthoDB" id="1924577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018972">
        <property type="entry name" value="Sas10_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF8">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09368">
        <property type="entry name" value="Sas10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sas10 C-terminal" evidence="6">
        <location>
            <begin position="432"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="412"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="507" mass="57825" checksum="AF2A3C4964C01FC7" modified="2022-08-03" version="1">MGRKGRHTARTGDGGAELRLQKQRVKEAERAQKEAELEFYDDPSENDASDDAESDGSEFGNEEEVLQLGESEEEESDEQDGDDEEEDDEEVDEFGNEEEKKRIDKMDAKWGKSRKNFYSADTAEFELEDDEEVAKDEENAALELQRKQATMMDDEDFGLDEEEDDEEADEEDEEQAPVDDEDLLGDQLADISMLVDEGDSASMEQVRKDFSKMTKKDKLLIVNQTAPELLGLSAEMESTMKELKEVVTPAILKLKEVRRRTKAYNTGLQYLVTRQNLMLNYIANISFYLLLRAEGKSVTDHPVLQHLLSLKKQMNKLQEVDDAVNTQLHDLLTQEFPEEDEDDGLDKFFQQQRKRTNTQSSKRVAATEAAKPSKKAKKSYGVSQAEKDEAEQFYEAALREKEALDQAKKQFYSHEKPGLASSDEEDSDEDDGGKRGASFEIIKNKGLKAHKNKLNRNPRVKKRMQYRKAVIRRKGQVRDVRVGEAGRYGGESTGIKSNLTRSRKLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNL6</accession>
    <name>A0A8K1FNL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNL6"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF74">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4 HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="45257" checksum="47389E7EC117E4D1" modified="2022-08-03" version="1">MEHKAARGGRDARGNTKRRRTQGFVRKWTLYPPRRVAADSDVPTVAKTFRVLSFNVLADYIALRDTIPDAEEPWKYDWAHRCRGLLREIRTWRADIICLQEVDHYEDFFEPELKKAGYKGVFKKRTGEDTHDGCAIFIHSKNFDIVASVPLEYHVPGHPLLDRHNIALQAVVDWRGDGAEPQRFVVANTHLLFNPGRGDVKLAQLQRLLTSLHELREGEHVLTPSSPLPVLVCGDFNLAPHSPLYEFLSRGELDVSGLSKHLLSGQNMEYHQKRGHHAVEHDSARHHGHGTAWGRFQSDRAQRTYHRHFPKDTVVNHSLPLASAYAQMPNDRCTGEPKFTTFHEGTKCTVDYVWFTTDSLHCHGVVEMAPAGQLFKAKVLPTASHSSDHLSLVADFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQM5</accession>
    <name>A0A8K1FQM5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQM5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="31114" checksum="399C9FDEFF31429E" modified="2022-08-03" version="1">MVQGYIYTLEDSAKGTVLGMPTFSPDTDGDCWTVECLTDNGWAEDFLQVLDFNIKDIATKDCVTTKIDPRICVEDGIQLTKADGQVLFDKAVDEILGEVARMQVADDAPTPVSGESIHPEDPDDYVMVSSDSDTEPRQGRTRRHWSDPYQRRSTWVDDIDGYVHVLRPTSGRLTRAERRRTDRYRETERARTARIKDAKESKRQQWLDLEYYEDSLIAYKYRLLGAYSERDREAIAASERAFRKYQEVATAENKQKANQIEELLRRMRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRA5</accession>
    <name>A0A8K1FRA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRA5"/>
    <dbReference type="OrthoDB" id="10266268at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000067">
        <property type="entry name" value="COP9 signalosome, subunit CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0736">Signalosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="46"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="41076" checksum="3388FB80E62BC4E4" modified="2022-08-03" version="1">MMASNTKPAEEPTSFEDAAYGVDEEVLKDVRANKVWMQDPKYFKKVIVSPSAAMKMMNHAHSGVEKGIKNGGKPVEIMGLMLGRPSTGTDRDVGDAQTLIVTDCFPLPIEGAETRVLADDAEVINYMISLGEAVEQTRKERFMGWYHSHPFDVEVHSHCFLSATDVSTQLQWQRSEDPNGNPWLAVVLDPLRSLAKKRPEMGAFRVYPPEYTAPVNETPDGTIVTDETTRMERWGSCWNRYYTLEVDYFMSSLGSQIVNILSEEFLWMRTLSSNTMQERENRDRFSERIQLLANKLDGCESHLAPRGRNARIGDYYVPEKQNKESEESALDKITQAANELAIEHSHGQELQLAKKALFNDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FT10</accession>
    <name>A0A8K1FT10_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FT10"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="583" mass="65799" checksum="B6F536830F00AE4F" modified="2022-08-03" version="1">MRLSEDEAWAIAMMWQEPLRGRVRLATDKSDSMRLVKSYEWIRFDASSVTTEQSAQAFGATARYAAITWLALSYVPGFSCAENPVFWRRVFDTLQWQEDASQLQHRSECFMDKRTISAVTDAIRFFPDENKPFPRFQLALPDRPGDSDVVTFCRAFCGALDHHDEVSDASFQATLARLLPLINLKGANRVVDVGFLLRGLSPNTLSADLNTLVESCSANLETRSTVFQAGVRPQFSVRYVAFRGYLNIFESSHATDLLPLISNAAVEIDQIYFSVYDAVTRHAFASFVNCVFQVDEQAHAHVRRLSFPMNYIAEDKFDAICSALPHARSVRTLRLDRRSCSSRTIQSRDVAWLAYAIFHPDAAESSWKALDLEMVNVSPEYAAVFRTMSRGNNLLAFLDDTPPTSQAYHSARVTEGTIVYSEPRLGEIVLTLDDTSTRFDVCVDSDDVTAMDEWTLTALRISTTRRTNFSSSREALLSILKRLPSLQYLHWDGPSAQFRRREANPIPYVQARKESWERMDISSTSRLAIARGNFGLKHLIALLSVIKKKEAEDSPLAFLNQDLVNEIATYAAIARPRDLSVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2A6</accession>
    <name>A0A8K1C2A6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">23S rRNA (Uracil-5-)-methyltransferase RumA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013926</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2A6"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045850">
        <property type="entry name" value="TRM2_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904:SF2">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="124"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="798"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="714"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="770"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="854" mass="93531" checksum="11B0F37BD19DDE79" modified="2022-08-03" version="1">MATVMTSKDEEMTTPVSVPEAATSTVEAMEVVSDAPTADATPNAVETSEEEYKLIVLNYGKWKDAKSMEQVLRERQVAFRKVQKSRQLSFGFVHFHTQEARDAALPVLQTIEWNGELMDVKTALPKKSMKPVRSNKKRPRTETEEGGAEDKPARQSNDGDEHEASAEGAKEPPKNAREVVTPWADVPYDEQLERKEAEMKKVMIKIVRQTRKEYFKKEKRVANEKRNSKKQKLEASNEDEEGPFSSNAKAFIPTWLTSHGSLYVVADSVLYSRPHEADVSTPWSRIVDAPGVTAIVSFGSELVAATTENIITALKYGPTASYWEKLCDGPSVAIASLASLRGSLLCCTTEGSILKQEGAGRFATGEWKELAVVEGARSITTHNGFLYACCPGETSTPKWQRAPLTADALDTLEFAPYDWSIEVPQMLGMCSHDHQMILLSGHSLAYAAVEGAASVDTRPLSVGTSEAVLTGFASHKGLCCPMDSIHASPVVEGYRNKCEFSIGFDANEKPCVGFRMGLFRDGSVIVSPPKDCVSVSPIMEKVCATVQDLIESSGIPVYDVKTQVGVWRLLTVRHSERTNQLMIMLQVNPKGMSPEEKERLNQLVLEKLTDSSLDYQVTSLFLQEYEGVSAASENDPLVHLHGEKTIEEHLLGMRFSVSPNAFFQVNTRGAETLYSLVKQHAIANEKTLLYDVCCGTGTIGICSSKGTGKVVGIEICKAATDDAVVNAKLNDVTNVSFVNSKAEDVMRDLLKAKPTGEGDAELSRVVAIVDPPRAGLHHQVLRSLRSCPPVERIVYVSCNPTGSLIQDAVTLCGPKTKSITGNAFEPVHAIPVDMFPHTPHCEMIIVFDRVNKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2A9</accession>
    <name>A0A8K1C2A9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2A9"/>
    <dbReference type="OrthoDB" id="10266080at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="1">
        <location>
            <begin position="6"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="1">
        <location>
            <begin position="142"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="855" mass="97413" checksum="26C53474985D1D24" modified="2022-08-03" version="1">MELRLTLEDVARDAFRRRFFLDAFDDEREALELCFAFLLQVRRYKQLVGQREALQHLAQDVANIYLRNPPPHLCVFLPSPAIDALIKRILASVDGGRSPLDVFNGIEAHVKDRLERERFPTFLTQPQYQDLCDAIRTRREIPLGEILVDQRRTRYLEQFLQQTDPTAIGNLLFWVQVQTAFLPLIQTTLFSVALFEEIQSTVRRLFNLFLTEGSQFNATLVPDTMRKEILKRIMTLQGEPFSPPRYANLFRQAQDKIWQWMQTTLYSSFQNSAFYVLLVVEIENLESDRQLRRLSDHVQSDLSDKKNELKQSSVIFPVEYASEGPSVQEYSPSLPAECVLDVSPERLAILPELTDTLMTTLQLATMVGFTAKGRPQFQRDLVVCESQAAASDHFLEYVSELQDLSHARAAASPANKAQPSAPSPTFHSFVLPRRKGTSFGYCLTTWHSRSDEIDTSDPTKDEHSTERQHQHSLPRFAYCLFTQALDRVCAIKLLRQLQALDTLSPVPNVRELLDTISSGPLPQQPHRAFSQRFLDFYLESWVPSITFPIHHIFRELSHQTVVSVLGSLLCGKSLVMVSQRSGSLLLAGQALLELLKPIEWKDLFLPFCPLSIAPSLVEDGVFASPSKSPFIVGFRGELVHLKLKESTTDQRHRIRNSLYSTHRASLQLQCGSDMYPEEVLRSPAIVLDIDADDLYIPEQLELPELPQSVVRQVESWLTEAMLGGQVAHADSRLFRPSVSLSFLSDMAGKDALNIVDHPLSSDDSVRLAAIGFLEALFGDVVFHFCSFRKAVATQEAEPDETYVIFEADAYLEARIELGCRDFFRHSFQTELFRQLLMRYHKRFSLFRPANVSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2C3</accession>
    <name>A0A8K1C2C3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylmalonic aciduria and homocystinuria type D protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2C3"/>
    <dbReference type="OrthoDB" id="10263782at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009235">
        <property type="term" value="P:cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019362">
        <property type="entry name" value="MMADHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192:SF3">
        <property type="entry name" value="COBALAMIN TRAFFICKING PROTEIN CBLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192">
        <property type="entry name" value="MY011 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10229">
        <property type="entry name" value="MMADHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="22126" checksum="CEF251DA075FB09E" modified="2022-08-03" version="1">MAARRALDTLLAPTEVQPGFEVSVHNCPKLMLRELKHVFPAQFETKTIKNATMLAVITCQKALMDLSQFGVDADQEKDRLLETFVEFAQFVTTKIIEQQYWADFIDPCSGLPMLTLPSNKVYSEVDGVELLLRYRCLSAGMCKILLHPVWGGAVYPASLFTDAPFDVVRHAVLSFSSSTSETSQSPREREGEEPNGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C372</accession>
    <name>A0A8K1C372_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C372"/>
    <dbReference type="OrthoDB" id="168171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324:SF2">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="274" mass="31053" checksum="A9F57BB9C0D8C8AE" modified="2022-08-03" version="1">MTERKPWDGDAAVRHGKTSLDVLLAWLQQEGNYTRWRGESTTVRRESREELCREIVLGMQRHGLFHRQPRHVRTKINELERSYGNAIGWMDQAGTLLMDDEGGPEYVRSRLHRMCKHFSLLHAVMGESVPLQVSTEPDMGEGFPPCPADGNRSVVSPMTDDSAHEAADARVDDNNAAMTEDSTPDPTATKKRKACTLAEWIDVDLFDDTPLLTLAERKFKLEERHATLEAELLKWQVVQARVESVKKLVLTRVELRQAGVSEAEIDALLPVLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3I1</accession>
    <name>A0A8K1C3I1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoside hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3I1"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035459147" description="Glycoside hydrolase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="41531" checksum="6F4EB43616E57E43" modified="2022-08-03" version="1">MKTVVRATAFLALCALWASDYARADDAALCSISPSTYASAKTEYPKYKVAIEQLENRGIATWYTDREGSDEHTKVAKRLIEACDDSTRLTTVVYGLPNKDCEAGYSSDGGNKDSEEYETFISSLADIVGDRKALYILEPDAVGLLGNGEDSCAEKYGYRDNLKSAIRILSKNLNADIYLDVGFWRLANSVKADAIAKIVRNITSAGRVKGITLNTSNYRGTRDMVQMCTNFQTAYGSKDLGCIIDTSRNYNAYTGEEWCNVRSGGIGHPPTSKTGIDNIDYFVWVKPPGESDGECDGDGHTSDAMVGPSAGSFFAKEFELLWDQGYFVKEEGMASVGSKSGVSTGAIVGICFGVVAGIVLVVGGIWFKRRQSSRPIGTNFAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3L3</accession>
    <name>A0A8K1C3L3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">N-alpha-acetyltransferase 35, NatC auxiliary subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3L3"/>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="6">
        <location>
            <begin position="389"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="92036" checksum="0277A0444DC60576" modified="2022-08-03" version="1">MAPSADSAAAKAATTAMSQWQDVTELFGTAAKELKVGHLVHVESFNLFDSMSALELMDPKMDAGMALHGAAPLSIADRLQQKSIPLSFTSARDVLATMDLLFRHEAAWLNGQPLAQTLLTCVYMHRDVIRSLLEALVPRDGSEKSVEDRLETALQQLGGSVSDTLSLVMATFTLMILHTSSHVREVVVRADIYEEEDFSPGTGFDLSIFEWWTRPATEMLLIHTIDRLEKLLAEQRTAAASRGSSKKASKKKTGKAASGAQENNEKPVDSLQGLHTNVKISVSYCEAMLRRLRLRKVLYLVYNEMGLAETLCDLAHAREQFASAQELLKSFATEPLEFDPECLSGKPFGFDPALNRLISSSTPPREVALPTLDDALAIYQKLLEELVAVCSPGVWTTMEEVRVFLSDFSRKKPGIIARSFVLLYLYCDKKIYGKHGFMDWLTEEMVLNGVPSVLLSTQEGVQFSSRSIETVYESLKVYLFNRSRQRARIEYLLEEWGVLQLEASVIDERFTTEMSIPKATYPRYFTAWTLEQVVVLMLQYVSLGFELELYAPSEYSMVYWYLDYLYGSRLQNLNFTWGFIDKMKEIMKDHPRGRGKAGKEENQAGKDDTEETMDPTKARYLREMSYCEMQRSLMRAFFQAFAAMEREELVSATLPTYGTHAIRFQHRFAPFQSLQYPAPLVYEDYLKNSDFSRFAVDLIYKSVEECFKATRTHAEQALLSAISASTATEDETGDATTPVHGDEIKQALQVAIANAVRLARREQEQAAAQGKAGRKSRNHQVSTLNAPTTFSDAVEFSLHPYFPLLRLSRSGPSSERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3S8</accession>
    <name>A0A8K1C3S8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3S8"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF57">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="70"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="36306" checksum="815E9771F512A8D3" modified="2022-08-03" version="1">MGKQGRGRRLTDKERMEIIALTRQNPRIKHVELAVKYNVNESTIRKWRAQDNAKKIEARYHQGVTAARDLRQRGQAVRNAQFDAALYEWVSAMLKQGVDLAPVKVREKARALAVGHEGMEDFKASSGWYYRFCRRYGIPCGSLARVPHPIDQSALPITTSIGNGTVEIPAHSMASLQDMTSSEGTNTLSGNSPVRIQHSASHTDNDLLLNELQGIVNSLRNPPVATIPPRLPSSSAVVSSPGSLMMFTVNQTAITHASHHFKDILTPQARLRLVKHLSRTPGEAEMYLVMDDETRLEYVKEFSLADVAESGSMQHSMHENTSTSTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4E4</accession>
    <name>A0A8K1C4E4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008843</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4E4"/>
    <dbReference type="OrthoDB" id="27911at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="230"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="406"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="622"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="667"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="812" mass="89045" checksum="738395320BCA4A1A" modified="2022-08-03" version="1">MDATLEHVAVGCNAISNAFGGNSASPTSHGTHTSAFCGAFGAKNGVALIARQANRPALLEIRHMLQHRVSTKDSTRITSVYLHAPVDGAPRRVLAGDSEGNVFLWLQADESTEWTLHHLSSSEQTMHSVSAVTAVATRRRWLYVIAFSDGQLRVFEQRHESETVEPIATLSLSVKMIMETLSSTVWTQQGKEQEEEEEEDALVAAGGVDSKVYLFEIPSTKQAMNQLIALEGHRGWIRCVDFERRAASDSSSLLLASASQDQRVRLWKISSAPKTEEHVAPGYHAVGSTAVYTISFDSLLIGHEDWVTSLVWTLLPEAETSVSALVSSSMDNTIIVWKKDANVGKSGAWVPSLRVGEHGGNGILSPAVLTTSDYRLDLLALNFSGQLERWQQQPPPSKIFLPTASLAGHTSPVTDISWSPSGDYLLSTSLDQTTRILAPLQTTGSWHEISRAQVHGYDINCATFLAKTPSDHNDRFVCGADEKILRVFEAPDSLQELAQALKGETKSTEEDTESTRVQHAYLPELSLTNKTTVDQSDKKKKHGGFAVVDVEQNLEIPVGDTLARKTLWPEQRKLYGHGNELLCVTSNHAGTVIASACKSREERFAAVWLWNTTDWSVVQSPLEGHKSSVVQLAFSPNDEFLASVSRDRQFCVFQRQADEKYTLVDRVKAHKRIIWSCSWSPDSTLLVTGARDQTFAFWSRSSDSSKWSQLGENVVLPSAVTAVAFAPFALDEQSRKYLLAIGLESGHIQLFTVTVDDNNTLVSSLALELLLPQVSSATISRLAWSPSSTSTHGLLASASADHSVRLYRIALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X1</accession>
    <name>A0A8K1C4X1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X1"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="51"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="35134" checksum="1FB34C921EED5567" modified="2022-08-03" version="1">MVLLQLFDYLIVPTIQFARFCRGFHAKNVSIDEFEWHYIEREGCAPNETEPVIFVHGFSSWKESWLNVASRVDKKYKVVIPDLPGHGKTEPADPLMSYTIKEQTERLSKFIDKTIPAGQKVHVVGCSMGGLIAGMYSAMYPDRVRSVTLICPAGLTMPKKSDAYHVLENEGKNLLMAHTTDDVIEMNQYLGFKPLNIPRMIASTIAQHRKRTISVVQRIFDDMSTEPTLLEEYLHLIQAKTLVMWGKNDRILDFSSFPIIQEKLSNASKKYTIAFDECGHTVQHERYQECANAINAMISGNEPTAVMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y9</accession>
    <name>A0A8K1C4Y9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_006627</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y9"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="504"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="544"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="582"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="18">
        <location>
            <begin position="168"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW56617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="640" mass="68923" checksum="006F18D4FA02998B" modified="2022-08-03" version="1">MGKKKNNKSKAASPPKPAHEEEEKERNEESESQVVADPPQAAEKQEEEEEEEEEEASEDEEPMLMPPPRSISPPPPPPPQVHPLPQPPTPPTPPPEQPAAAAAAQPPSPPTEPSMSQPSRPTSQPPPPPPVLNPAVVLPARTNPPGREARKQTGETPAGKTKNQLQLSAWLIALSSFLWGYGVSVLNVCIVPDAVGSLLTEINLSTHEQETATALVLVGALVSALASGTIGDRFGLKTIILVNNVFFILGGALCAMATGKTTIFVGRFFIGLACGIVTNTVPVLLNEISPAQRRGQITSYHQLLLTIGMLVTGMLGFAVIENVPSGWRYLNAAMVLPAVLQVAMLAWIPESPWWLMKYKGKSQSRATLMRLRDASRVDAIEAELSEIALAMETNAVARASEWSDLREFKSTVAMGTIMVFFQAMTGINTVMLYSAKIFHFAGVTNPFLATAVVGVVNVVVTIFSVSLVDSYGRRPLLLGGTLMMILALIVLSLSLLYLNNDLKVQGAIAVVSVLTFVAGFAVGLGAVVWVVLADITPVKIRSRAFAVFMGVSYVCNILIAVYTLSAISFLGRGENPEKNGIAKLYLILSGVAVASLIYIYSRLPETKNPKDMHYSEEHAALLLGDQDDEETFLRSNRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C580</accession>
    <name>A0A8K1C580_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C580"/>
    <dbReference type="OrthoDB" id="165860at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36939" checksum="4310E1A2418639C9" modified="2022-08-03" version="1">MADGRTTLSLDELYDAHASKATYQRLVDVINRQATLVERLEKRVRTLEATHRDAVMAQQQSVHQLDVVVQQLQLVQDRYDTLQKKYDVQEITTSQLVEESREHGHGEGEIRDALSQLKRTVETSTKQIRSEMATMEMASRLEDHQSELNARLTSMERRVELKLDKSEMTRLDGVVAKIQAFAPTATELSGHVKTLQEHQTTVEHTLLQQMETGMRLESNLLDVSKLIADKMDKRDWMDFIRTQHKPLIARFETEVSELQDTTQQLVHRGASLESRHQTLASKLCSVSAAMNERLLQYQATMDAVVKDKLSNSPSARLWRFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5X9</accession>
    <name>A0A8K1C5X9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Folate-Biopterin Transporter (FBT) Family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5X9"/>
    <dbReference type="OrthoDB" id="153467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="61957" checksum="68B22B2A8F071222" modified="2022-08-03" version="1">MTTRVSLVERISYISSTANKDKEIDGGYISATTPDVEGGALRAGEAPNLLSKQSFGLLAQYAAVGLIYGTLPYTIYPFLTAYLNMEGTATTSASALLSIPWSLKVFIGMLSDNFPIFGYRRRPFMMIGWSVCALCLFVMAFMPMPDSYFIKPEYRKLEVEELIDGVHVRENAGSSGGKYIVLMMLASLGYVFADVAADAVVVEYAQREPEAIRGRTQTAIYTTRTFFMIIANVMLAFGMNGREYGGDFDYGMSFSNLMLVLAIFCLPVVAMTWFFVHEERFAKPNFKEYISNLWESIKTRAFYQVIAYNFFSGVFSSVSYVASSPIQIYWVEVTNLNYNLSSIIANGVMVVTLIVVGKYGLHWNWRFVIAVTMVMVVAMDVVCTMLVTWDVFRSQWFWLGVPIVENVPYSVNFIISTYVVVELAGMGNEGACYGLLTTVSNLSSPFALTITKNINASFDVWNKDIMSDTTHVRSEVTYTIMISYFCKLASLFFLVLLPSQKAATQELKRTGGSSKTMGIITICYCMFALIWSIMTNLFAIFDSTKCLKITGGCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C645</accession>
    <name>A0A8K1C645_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C645"/>
    <dbReference type="OrthoDB" id="165506at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="241" mass="26835" checksum="A2D852DC183B6841" modified="2022-08-03" version="1">MTALPSTSSKPSKPPVEVSKAVSSAFLTACASGDAEKTHGALLQLQRQYPETVDARVHEILPAIQELLGRGLVTAATQNHTLLLEYLVSGSYANVFRDGVCLTDAAFPAFATLQDHELRCCALSVRFVAFAALTCIDKLAFRGFTFFIETESLWGFEVTWCLCLAMRKALATFASNVETPATSYHPFILLLTQHYRFVIQEIHTFHERFRPSKDATDDELDQLDRLRALQASLLYEITLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6G6</accession>
    <name>A0A8K1C6G6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6G6"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14834">
        <property type="entry name" value="AP3_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000001">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027155">
        <property type="entry name" value="APS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="10">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18775" checksum="3987ACAAD18C6EB4" modified="2022-08-03" version="1">MIKGILIVNNHGKPRIVKFYEHVPDAEQQAVIRDIYTQVSKRPDTLCNFLEGTVRYWGDGVKLIYRHYATLYFVFAVDQQESDLGILDLIQVFVETLDKIFENVCELDLIFHSDKVHYALDEIVMGGMVLETNINEILTAVNEMNRLDSNSTKRALPGTSKARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C723</accession>
    <name>A0A8K1C723_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)(+) transhydrogenase (Si-specific)</fullName>
            <ecNumber evidence="4">1.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NAD(P)(+) transhydrogenase [B-specific]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_003147</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="12">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C723"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003957">
        <property type="term" value="F:NAD(P)+ transhydrogenase (Si-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF93">
        <property type="entry name" value="SOLUBLE PYRIDINE NUCLEOTIDE TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="50"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="433"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="247"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="561" mass="61754" checksum="4F4015644429E398" modified="2022-08-03" version="1">MLTSSTRRALLNGRQTALASRAINSVATIDVSDRKPLSEMLQELKASEHFDLIVIGSGPAGQKCAIDHAKHGKTVAIIDKKDMHGGVCVHTGTVPSKTFREAILHLTAHRHRSFYDGASKPQKRFGIEDILQRVRKVENAETDITRHQLMRNGIELINGTARFLPDPSQKMVAVLSNDTYETPTDTKRHKSADICKRVLTADKFLLAVGTRPARREDIPFDGKTIFDSDQILWGGIQSVPKRLIVVGAGVIGMEYASMMSIIPGTEVTVIDGRKEILDMADKEVTEALSYAMRQTGTRFYTEETIKTVEKADNGEVIVKLNSGKTIIGDGLLYTLGRQGNTDSLNLEAVGLTPDKRGLIQVDDNFRTAVPHIYAAGDCIGYPALASTSMEQGRLASVHMRSYKPVNKMKPGSENEMNDPQYMRTRMRSGEVFPFGIYTVPEISMVGKNEQQLTRENVPYEVGLARYEELAKGQMMGGVPGFLKIIFCPNTLQVLGVHAIGEGATEIIHIGQVVMSTGGTIEYFRNAVFNYPTLAEAYRVAALHGLSKIESLKKFGSQENHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9F4</accession>
    <name>A0A8K1C9F4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9F4"/>
    <dbReference type="OrthoDB" id="1607513at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02892">
        <property type="entry name" value="zf-BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00614">
        <property type="entry name" value="ZnF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="10">
        <location>
            <begin position="108"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="11">
        <location>
            <begin position="880"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="594"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="106777" checksum="7B6F293DA39F7F27" modified="2022-08-03" version="1">MDPTTLMAVPVPLEPSLHGKGKDATSEDTAVPLPASSQDQDDHDDDDQDQDHEHEHDEEEDDERAHHAASTTSASANAAAAARRRARGVGRMRVNDKGEPTMMLPSFIWDFFVKEANGKYVVCTLCPPNTTRFAYSGGTSTMNRHLRKKHQKYAPGKTAADYEYPKSAKRHAVGTTTTSVGVHPSAASHLLLATSSPASLTHHNVLLATGDPTAVALGAMMSGSLSPSDATRRHLIDLRNARRRATNAKRRKLLHGMMDTEQYTQAAASTPTTNAAAVTPSAADFDPSGFVTLTHATTPGASASTTTSGLSFPQGFELSDSAIDLAPHTTAASAASAVDVRLFDYAPSLTGTLGTLGYHAHARPRRNTPAHQKMLTHRLLKYLIAQYEPLDVSRMGSELGALVNGLEYPSPSLKLPSEDMLKLALANLYYSQREILKEVIADVEVLSLSLNNWKSVFGQNVLTVSGHWISQGFSRRDCVLEVYVLPLDETVNTVALLRDVMDKWEIPTSKVAALTMLTNGKEETVLHDEYPSLAVVNCFVHVLDNAVSAGLMKCAPLIRRCRNYVSYFIQNPSEYQIFLSLQRRVAEANLGAAMAGTDAAGEDHDEDEDDVDEQDPDKTTGSGRSPKLTGAVGGGGSGATVSPLPMPTLSVICDFEDRWNSTSEMICRIVELEQMLLLYKSNLESDTNPNRRPMQLRFVCCELSSEEWTNLKELARLLEPIEGVVHITSCEYPGLSIIYPLLHSIRKHLDDAELWVATSLGAAVRNAIANGLGNLELCTVGDTASTSPYLACLLDPRFKSLPFLDPSERTRLIAMLQRLHLELLGEKDDDQLTHDKKTDKSGPAGSSVVAASHKSKNAILHEFFPLEEPTNELDKLKTQVQQYLDSPSLPATDESENDPLEWWSRYQRTFPYLAKLAKKYLCMSAVSVPFFEAFTNYGQLMREKKARLDIEVAAQILFCRSVSRIPEMERMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Y8</accession>
    <name>A0A8K1C9Y8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Y8"/>
    <dbReference type="OrthoDB" id="10536883at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899">
        <property type="entry name" value="DOMAIN OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899:SF1">
        <property type="entry name" value="PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="249" mass="26911" checksum="CA6960E14A8C5534" modified="2022-08-03" version="1">MFAYPQRVITKASPQYSVGFTARASPSSPPSSPPSPPSSPTYCLSAVVIAWENVLFPLKWLTESAEFSLTQQGIEATKLKTRGNPFLAQALGAIEQQIIGTLSIIAPKVPVYIVTESCTEAVEAICATFFPGLRAYLGSTRGRVQVLPAVGKSQVEQMTSKLNQLQQICVASAATMEANKTQTPFKILTITADEIDRRVTTRMQQTMARFGAIQTMHLPALMANGKPLSLVDFHKQLQKVAAALAKEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAG7</accession>
    <name>A0A8K1CAG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAG7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="199"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="50729" checksum="59D12A33A901D3A3" modified="2022-08-03" version="1">MRCDCYVVRRSFPTHALPAMVSVVTKSSSRHPIPLDKALRLLRSRVIALLLNLNGAKLRGMVLRGGSVYAFFALMLGGFYDKPWELVEVASRMSFTIVRAIAAYVARGCKPLYPGWTLPFEVTRAVIRCSMSVYGDRLLVPSNAQFVRTQSEWVGTALGFLSSWQMGTKTEAFHHNGLEHMWVRNAKRSVTPNTRRFVVLYYHGGGFAVLSPRMYIHFANEMQTRIAKMLHEQLGDHEDDTSIQVEILLANYRKLPEYQYPVPPEDAYKMYEYLLHVEKVSPNQIVLAGDSAGGSLAMSTLIRIRDQQPTQPLGAFLSCPFVDLEVGGDERRVPHCLIGDKASDAIYTAYHPRNGPPSTWGDASPVHCDLQGLPPVYIQAAELDYILPHAQNLYAKAKADGLTDWTLDVHKEVPHVFTTFPTSIIRAADKGLDDMARFAATQFADSIRRPQCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK4</accession>
    <name>A0A8K1CAK4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK4"/>
    <dbReference type="OrthoDB" id="117324at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32677" checksum="AE9B244C00065DEF" modified="2022-08-03" version="1">MRFHGESVLDASLAFLDEIDELPDLPDMANHLEAALIDPTEMMLNELLGLANADEGNARIPDPSATTIVMSVKEETGKPIKTRKKGSKPIGMGTKAARKQEIEFLRTQVQELEGELSRLQKGLVPSTEPTLWERIAKRQRDVRKQHEAENTELRVLYQGQLKVARGLVRLLHRGQADMSSAWGNVKRRRIIEADEHSGQIFQSIRSLVARLVPVDKWMEESGFARIYDTFDDARVCCGPENDIFLEILLCRRFPFPFEATVEAVWNHLCAATIELETAVYGAVERSDMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBN3</accession>
    <name>A0A8K1CBN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBN3"/>
    <dbReference type="OrthoDB" id="91802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="40395" checksum="AA53FDEE456F174E" modified="2022-08-03" version="1">MKLFTPLTLGGKCEPIKLLHRVVMAPLTRLRAGGDGVPGEPAVTYYSQRGTPGGLLISEATNISATARGYFGSPGIYTQPQIEGWKKVTEAVHAKGGKMFLQLWHTGRMGHSDNQPGNILPVSSTSKHPVEIESKKVTTPHGRVPIGPSRALRADEIPGICQDYQDAATNALEAGFDGVELHAANGYLLEQFLYDSINDRTDEYGGSLENRARFLFEALDAIVSKVEAHKVGIRLSPYGIYFGQAESDPVATFNYVLSKLNAYNLAYVHLIEPRAYHSPNPLAPSEGAAHQFRGVYDGVLLSASGYDRMSAIDVVERGDADLVAFGRLFIANPDLVKRLQQKAPLNAWDSSTFYVGQEHGYTDYAFLHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCC3</accession>
    <name>A0A8K1CCC3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCC3"/>
    <dbReference type="OrthoDB" id="117310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="246" mass="28113" checksum="2C4EAED29C70D684" modified="2022-08-03" version="1">MAKTDLQSRPAVEDQAVVEDKKKQLREAAEAKMEDERKMMAEEDEEVDETFLALQKLLRALNGSRANVVVPMGAPARSGPSAANTQEANAPQSPEELLETRRQERERFRSSLMSAKDNQRYPTYYYYEEDEDEEEPSVESQISNRVISGSFSRLNVHIISRERWSTEEAERLPLVLLPKDGKVVSPAENPKLNIIFSREHEELRDQLVAALDKLDSENSSEQTRLLTPPQSTWTIQMRHFDSVASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCP4</accession>
    <name>A0A8K1CCP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCP4"/>
    <dbReference type="OrthoDB" id="64619at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="523" mass="59507" checksum="4680685F68B60C35" modified="2022-08-03" version="1">MSWLETELHDDPATLQAALAMLDEMDDSPSSSEVSDLSADLIPYGNDALEAENAKTTRMVTGNRTRNRQRNELLYLREKVAQMEETLAALRQSHGASGSENAVVVSKAARLWEDLAGQQHEHRRAAELENAKLRAMLRTQITTGRDLMRLIRKSSRGLDESSMLVRTRRRGDVGASASVDDLFVRLQELYSLTDTVFSNVPSGENITMLRDFTTSEDDPNTTTVNSYSTWTLPFPMERVVEATWQSVVRESTKAPALGVSEDDKAEKTFSTFRWDASEAFKWMQGEIHGRMGAKKFADHAPNEAVMGAITMEGDAFDRLYERLVVQSKPRSSKGGVKRKSKTLLKKTKPEALRRDEELSVDTATEASDPTETTLPSASEEPVDKESARQVLTRMRMRRNFHALSRQFRRHSLTLAVELIASYSIRRKLLRLRIKQRRSVWRPQLTRKERRRDKVQRGVRLEGIAARLHKRLQRDSDSTRDQDDTSKPFYVLHDIYFASPPPFHSKIHYKNTVDSNPVPPPPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD53</accession>
    <name>A0A8K1CD53_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD53"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024453">
        <property type="entry name" value="Peptidase_C92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46653">
        <property type="entry name" value="SPECIFICITY PROTEIN PHOSPHATASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46653:SF1">
        <property type="entry name" value="SPECIFICITY PROTEIN PHOSPHATASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05708">
        <property type="entry name" value="Peptidase_C92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="70"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="427"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="749" mass="84353" checksum="AE59AC8131C519F6" modified="2022-08-03" version="1">MSSKVKDGLFLGDIDAAQDAEFLQLNGIVHIINCVPRQVPNLFQQSLGLSYVTCDLDEILRRSFFDLRNREFMGIVQLIDRALEHTQSVLVHSLNGINRSPSIMIGYLMVKYCWGVDKAYEFLLTKRADIKPHESYIDQLCALETQLQSHYGARATEQQMFEWHPKLADQKNDELVLIHTFLNSTSPPTGAPKKLDENKNIVRRLTWVDHSTQLKKLYPSLLIKPERPPNHSYNDMLPANASSVACERSMRMMQRTLSFMVEVDLPTIRTSFVITASYRIFGITLGALNRAIVAIANANLEDRPKTSWSEDPSHLWLHVSNQQGTESAFLINSAGEIYGSTEQTCAQPAAADNSASMQLLLCSRCGIPSGCHCGWRSVHSLIPQHRDESVAHLLRQFAPSTSSSRDRQQNSPLYLRVTTQLRLPEMWLEAAVAAYKVVDPIVEAPRAVYSIKVEYKGKQWSVQRRYREFEGLHEELRGSLPTTVTRFMPRLPTKTWSRSLDESFLAVRRNALSVYLRDLLLINETQTSVAALAFLGAISTARDEAVALRREVLHLRVMSYYLDSGDLVLFQSCGPVSALQRSCTGSEWDHVALVMSSATSKKNYMLLEATGEGVTLLPMRSRLAAYSAYHTRRISLRKLQTPLLSYAVREDLLRHFATRVQSCPYGLSLSKLLRTNETSRSTSDYFCSELIADAYKAMGLIRPTLPSSNFWPSSFASGAFVDVELARHGASLDTEVLIDCHLLEVAFCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEB8</accession>
    <name>A0A8K1CEB8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEB8"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000004">
        <property type="entry name" value="Peptide chain release factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1660:FF:000002">
        <property type="entry name" value="Peptide chain release factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050057">
        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001859">
        <property type="entry name" value="PRK00591.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="5">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="40299" checksum="521B15EDB4D67CE8" modified="2022-08-03" version="1">MDLLSKRYDELSSELSSNDGSFTAERITNLSIEMADLEPKVLAVRELRDKQLAVEELDELIADKSDSSTDAAELREMAAEERRELLEQIEELETQVTRLMLPRDEDDDKSSILEIRAGTGGDEACLFASDILKMYQKVALAKGWKFEILSIGETDLGGVKECVCSITGRGAYGRMKFESGVHRVQRVPVNDVRVHTSAISVVVLPEVQEIEMNLDPKDLRIDVYRASGAGGQHVNTTESAVRITHIPTGIQAAVQDERSQHQNKAKAMKILCARVFDGIRRQRDKERHSMRSSQIGSGDRSERIRTYNFPQSRVTDHRVNVTLFGIERMLGGEHLDEIVDALVVNEQNELLLQLDHTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEG9</accession>
    <name>A0A8K1CEG9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEG9"/>
    <dbReference type="OrthoDB" id="168444at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="688"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="744"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="771" mass="87551" checksum="798051E3FE156EE1" modified="2022-08-03" version="1">MTTARLHDEETWRLPNWEEYSESGRSAWTEGDVSEDSASRVSDEEEDETAWGRRRVATLGDALAMTTTVTTPRRARLDLKALHQRYAQQRAQLQEESKASEPVKEVIDTSAIVTQQSLITTQLASVREQLQDFQQKWQLSVETTAQTSVEASEQPSAAASARENDVQKDLEAKEDALLQWLHLITQKVDVLASSFHHETTQLPIRYPLQPHVPEAGSDGQAPQSRAPTLSSWHVGASLQDHVSQASAERLLDLERSVACLVTATEQTTQRYVSYFEKIVQQIQELHQQRLRQVVEESLQEMKTQRTRYKKRVEQLETECQEAKKAMDVWRERAATLGNGTAEEKQRLEQLVVTTKEQAEVESSRLRNELATLKEKLDEVTSHRDRCTLTIEGLDRQLEQSQNEAREAQLQLRVVNADMERVQKRLGEQEERSHQQMRELEASNEQLRSQLFKAHENALLGRGDLEQKLRQELQVLQRDAEAAVLNRVLPERLELLQQKHGDALREVEENWRRKLQAAVAEARAANPVAQVMNTSTQTEMDRTLDDSMDTEDRIVRLSRRCRALENLLDKKFEVCSVASSPSRRSQRLNASYTSTHSMVSTSRDRSEFGIGALTLPLTDQSSYLADTTFFATENQYDDEDDDEEKPMRPPAWDASSPVGSSYLLKQASTPTGPTTEDVMALVRKLEMLARPEDDDEKHSVVQPDEEPELEKFSSRRTTPRAMVNNSRQAPKQSISTDRPPRATRKSPVPSASARARAKSALGRVNSVTSPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEL6</accession>
    <name>A0A8K1CEL6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEL6"/>
    <dbReference type="OrthoDB" id="108788at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="431" mass="49260" checksum="29F275DE03F1D516" modified="2022-08-03" version="1">MHPTCSADGKKVTILPDYKDWRVTSGPFAPFKVGPTNQWFDVMGLPGPVRDRMFYMVGKADSRQGLTLPTVKRQSFDRLIAQNTYGSTIADMMEISSGFSGSKHSYFTLYRIAGAMMTLPRLQFTFAVAGQSLALLAFMFGLAMRNGALNSYHLIHQILRLATFCIISIQLLYVLYYQIFSIGYVSNNPTLIDIYNKKIIYVAGVSYILLHQLDVRAAVTLWPRMANNDSYYFTRILWMISSLGVMIWSLKVKNPAHYVVATSSTCALGASECNKTDDFFFQHWWRRDRSEYSPRDYRHPDYLTSFEAYGCGGPLSDSYYYNTLVTRELPPWKGKDEPNYRTLQYLTCAKAVRDEGFVMLGGCYTLIRAKDIHVIMITKLLPRSLADNINLSGVVAHIQDHRLTPMRRVSYMSLWCVARRWDGRISYPDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFF6</accession>
    <name>A0A8K1CFF6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFF6"/>
    <dbReference type="OrthoDB" id="127884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="390"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="612" mass="69994" checksum="51E5A217D6BF056C" modified="2022-08-03" version="1">MSGRASVATMDRDDNEEQEVMATMEGLVQALTTQQEQQQEQWDESVVNKSNALRVASETPTTDATEVERADADQTETETEKTVSGERELDSVVTGGDVDKRVELVAALAIETTPPLPKPSYSVEALFPIVYEPATTATSTRRVSTRLPSAPENHNTDQIQQSQASHPPINTTKEPSTQPTSKRIAGPVDQRVQMLQKQVQSLQTSLHHHQIQFELSQSDRKQLAQRNARLKTQVRTLTTELTRSKAETAKLQTENELYAAKLPQLQQELLQETQQVDEKHAQSIQTQLEVTQLRAKTHVLQTRTANLEKQLEKMTEDTRARKKELRKKLTQFQQQEDKLKRVESELHELKTTRPQEMAQWKSRLASAIQRSDNERIKLESEMQRRHKEQLSESTLSLKKAQKARREAEMKSATLEQHVRQLQKTVQEQSEELRHIQKEARALQVLLRKAEETEATLRARVSGFQYERRAMEKRLRTHSETRYDSKRLEKTIRALKVVVSECEDDSEDGFDWERSELDPHDVARALCSCCAAIRDANPEKETETEKDQIQADTDPVPCEPCSRLQAELEKTREELMRTRELHSSELKVQANAYERVLASIRPTSARSTASECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT5</accession>
    <name>A0A8K1CFT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005327</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT5"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="60867" checksum="8FDB04F5FB79B71E" modified="2022-08-03" version="1">MVLQSLLETGEGMTSMGVNFATMGLLLVPIVLKAVTWLLAKSTDMHIGVANLPLVPPSTLPIINNLIDFVTRAHDIHHWLISLCEYFGGRPFVLRVPGQPDLVILSTPESVEDVMKKHFESFPKGEYQSEVLRDLLGYGLVATDGETWFHQRKVASNLFTARTLRETMTESIRKHTILLRQVLDKSSRTGEPVDVFKLLNRFTMEAFAEIGFGINMNSMEMETEHPFQTAFDRVQRLTVLRFIRPRWFWKLQKALNIGAERQLFQDMKTIDRIVLDIITQSFERRQTNEKRDGPTDIVSLFLDQYENSPEGKNGEFDPQYLRDIVVNFLIAGRDTTAQALSWFFMNMTLHPHVLTKIRTEIKDNLPQLMNGTIDTPTMDQVQQLTYLEAALKESLRLYPVVPFSSKLAMKDIVLSDGTLIREGQTVGFSMYANSRMKFVWGPDATVYNPGRWIDASTGKLVNYSAYKFFSFNAGPRICLGMNLAMLEMKIVVASLVSRLNVEVLEPEKLTYEFSLTLPVKGEMRVRVTPHKEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFZ7</accession>
    <name>A0A8K1CFZ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFZ7"/>
    <dbReference type="OrthoDB" id="116759at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="406" mass="44946" checksum="A1A670194156ECC9" modified="2022-08-03" version="1">MEPEELRAEQRWSSIPAQPTQSGYWPQHLDEELLVLVTRSTASRDRFPVGVNWLDISRSIGFSPVECVKRYAFLHDFRERHSSASQLSRKHQAHHVEEGEKHSEEVQAPFSGLSSSDDMGSPNSRAFLEYGSPVTSPRLESLENSGEFGVGSPSSPPPFALHLNRKQEASPSSPFRWETVAKEMSDSPVLLRAQARRRTAERLETSFGVRTEFEPGSDTQGTGNTGVQSPRIIHGTQNHSKFTDPTFAADIVSHAFKGLRMDDMPPSGTSPRLARVISNSEYPFLRAEDLSNTNAQATGQAPRSHVPRTASDPFLRASSPRVLGQASPLTSLSPTHSNDPFTESLTQSALEEAFLDMAGSRLDTSSMLFASRFGTQSRARLEQLQARPQQDRGQSRADHAWPSPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGW3</accession>
    <name>A0A8K1CGW3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome c oxidase copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005194</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGW3"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7573" checksum="E3630CCF6A348A3C" modified="2022-08-03" version="1">MAGKEGAQTNAAVSTTATTQPALGKSGKKICCSCPDTKKARDLCVVTNGEENCKELIEAHKICLRSEGFTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGY9</accession>
    <name>A0A8K1CGY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malic enzyme NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGY9"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="19747" checksum="42F1C8EC380F4EBB" modified="2022-08-03" version="1">MGLSAARGAFTQEAVEEMAKHVDMPIIFPLSNPTSVAECTADEAYRWTKGRCVFASGSPFAPVMYEGKEYAVSQCNNMFIFPAVGLACTVCQATRVTDRMLYAAAKALAECMTEEEIASGRVFPSVQNIRRVSLKVATAVMQCALDDDIAGFRPKIRRGASIEDYIASKMYYPTYHALVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHA8</accession>
    <name>A0A8K1CHA8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHA8"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="40183" checksum="011591BC1C3DEFC9" modified="2022-08-03" version="1">MFSFIADKLNVKNLGEMLAPTYTPEQELHAAIEQGMEDKFLSLLDEHNVSPHATNDGGNMPIHTAAYYGRVRMLETLLVRGIDVNTLGPRDNTPLHFAASQGHFEMVKFLINNNANPAKRNRNGRTPYDIAKGDGLRQYLLPLQFRHEDPNEAATMLPPGITPSVDPMAPRAEIAPPPMAGMYNPGAAPAPPQAAFNPLYAAPTHSAIPRGPASRIARPGEYRPIQADGFGTSVGNAELTAKYGNTREVKVTAPPPMLGGGAPVGGAAPGFPTPPVSSDGANPYSAARTAPSPTPPVAGGYPGFGAPPNSGGAPRAGPPQFKIFNPRLAANNNANATAAPTAPSGLYAQPVATASGPFGAPPPRAPGNTMYDGEEVTLSASASVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHB9</accession>
    <name>A0A8K1CHB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_002520</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Golgi apparatus membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPI-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHB9"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051645">
        <property type="term" value="P:Golgi localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000003">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="14">
        <location>
            <begin position="366"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="260"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="281"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW63579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="605" mass="66576" checksum="9DB1567FC4C40979" modified="2022-08-03" version="1">MVIQVDSRIYSKGGSHWKIQIVSRSPLVTVIVLSLPGKAAHDTETVVNWVDDLQSGMARIINAFFSFKTVLLRAFRAICSVTLISVLVARQFVEITRIRLEGLLTAFPKLLSSGSREHTFIDTESVRYVYQPLENFFVLIITNKTSNIVEDLHTIQLLAKLVPDICGSLNESAIRDKQFELIFGFDELIAAGGHSENVNLQQIRVNMEMESHEEKLHNMILQSKQAAAKDDMKRHTIRIKEEQRERARLERAGLGGYAKQTGFGSSMGNAFGQSPRGGGSDSYSSPTSSSFSSSNVPTSPTSYNKPAEPAAPPIKASGMKLGGASKSTGKSFLDAMAAEDDLKEIPPMSAPVQAVTKPEPTVTVSHDPIGVVVEEKITVVLNREGTLEQLEVKGSLFVSVNDQASACCRLKLRQSAANGITFQTHPKVDKRLFDQESVLGLKDATKPFPSARVAVLRWSLKTQDESFLPLNIVCWPEEQGGGKINVTIEYSMDRDMVLDNVNILIPLGSRESPQVAHVDGQFQHNSNEGSLLWHLDRVDSSNNSGTLEFSIRGDSLDAFFPLAVSFFSRSVYSDVDIEAVVKADDHSPVQFGFEKLLSTENYQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHP0</accession>
    <name>A0A8K1CHP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111297at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1795"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1756"/>
            <end position="1780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1937" mass="216353" checksum="98FE9E4258C8B8E8" modified="2022-08-03" version="1">METTTSDAMEANEMAMEVDARHGMLIRAINDYASMEAVAECSINALTTEITRLDLSETIRCDLAVAFLASGGFASVWVALEEFVDRKEFVESALTLLVEVLACTKRAESMIPPRRDWMPCAITVGRAIAIQSHDNVSILFLRVMELIISQTEGSSTSILQMDVVQPVVRALARRVDDPAVRQLLVAVRDAQEHYETADPPEQWKLFTNILSQHEKLPVSSRQVIQILSRVSKEHFEEGSMSERAFIEACAQHSQDDTRDGISMACQYAPVLSQRINYSEDIQVSPDLIKELVRVLRARTEPSELVLRISQLFLHLLTQESSYRNKLVDNGAVQVVSKLLYIYHDQDEEVFYTLSNLVTRISQALDVRHNSSILQTLGQKWKQSLTPPSDMDSFVESLELNCYVVAALCQVNDHGQAFIKNGCAVYYATLLRYNLQDRSEVSESTFQRVMECCLYALNTLVRLAGIEQADRIMNTTELLGLAIASVTEMLSQGQQHYPTLRRACTFTRSLLVHDSGLVDYCIESKLHNAMVSLLVKCTEPATLRSVLQITLSVVSGGLRFKEALIKEGFLQTLCDRLLRDDIQQVNESCVDLVIYVMEDLGQREDEVDDELSRISPGLSPPSSYTETLHTVRLASQDALNSLKTDPSSVVEPYLQTTLASLCDTLLSASRITVNGDQDASGLTWETAELVVSIRQRCPQYLHERFDAVAIALFRLTARAYRNSDPARCASSLKKLSCLVDASPTNSMLRIEYLNLLVMVGLRRLDRESVLESFDDICHHLRLLLCSLSNGDAGIQTIEMKASRFLSALGVKLVERWEAIEVAQVTTLLDILVSSTRLFKCLCEAIIGEPPGVDYLLAICIEVPSSSLQEVIVMFLAEHEIAISQATTRCGEKELKMVLLVIDGDPNAENPSRLTTRRRSEIIAGLRVLKVMISVQELAPLVNNLDGLAVLYDLLSCSTHDDLIFGLALDVCCAITQQEEAARAPHTLPMLKLLFLATEPRCHPDAFRSICVLLEQCTVLGSPSFSWTLAQLARTYLVKWTKKHSIELPIEGEESIIARLYQIQNDENQEKLKTDEAISDPEGCIPRDLVRQVTAEQLAIKSVILKYHQVVRCEMNDSMEVYVDVQTSAKTTGGVPREYVELQQAMCRLRWMLKDPLLCLNDVFCQEILPAICEIIILHSTTSDIVCIAVESLSRIAFVRPGRVIASKAIDLTALFAASMLHASRSLPFAIFAAALCENIALDVCDSDISTTVNIVEFLVSLLLYHEEDVDIISSCTFALSVLLPVVPSECLFEVHSNPLSLLTRALRNHAHDITITWYCLDCLRCVLAGTQSLEESVLDSIISSLVSIVKANVGHPFLVRSALETVELTHQKMKALARRALLETDVVDLLVRSLDTHQHNADITRVGLSLLLETQSAKAQSAINAEIIVQTASVVLKTCQRHIHSLDVCRLGLEILLRIVEGNESGESHGEVDAGHSDSFGVLLREHAAKTFFDEGGLRLVFDVFQTTHCEERDRLVGSALELLYDLTRDQEGRDRVASANGLYVIQSVIDRFAEHHDDELLLEAALDCLVNLACSNRPLRGWRSLIPWLIGLIDALQTRHSTTACLEKLIGILSRLAVYQEMGSDISHYGAYCILQTLAYTENNVFLEQALFTLLWQLCFHHADIPVLVTFDAVSITLERLPDHIDAPNEELLLHSLRLLSAIGSYEPCRDALCDDSLAVLLCVIRDSPSYTAKTRQLSKDMLDRISQREQVTRLEENSKLQQVQPSAQAPKEQDDRSPEVVEVKLTKEDRVHRELLLRGAVFRVRRNATQKKRDKMLINLAENGQYLVFRELSSANVQLERIFLSQVEVLPNVNDSTQPSSAKTSILLTRKLSKPALVRATSRAQCIFHMMIRKELMSLEASSPDERASWEHALAWAIGQVSKSTKLIRNSEDSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ73</accession>
    <name>A0A8K1CJ73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ73"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="199" mass="23431" checksum="7FC82062F87F6540" modified="2022-08-03" version="1">MKPSTRDAFRLPTPVNDAVPDDESCVKTERRMSTALIIHPLSMYSPDKTQKYTPEWYLAALAFQQHEMEQLKQQQPTVLQPSRRLCLLDYTCDDNVRTILSFLDGATLCMTRRVCRYFNELAENDELWLHLCKAEWALSPDQLRERPASYQALYKYACQSLRRMIREFFEEQCLSSLQNSFRIPRDTAISIARRSFEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA6</accession>
    <name>A0A8K1CJA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LRAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJA6"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46137">
        <property type="entry name" value="OS05G0310600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46137:SF3">
        <property type="entry name" value="OS05G0310600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51934">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LRAT" evidence="1">
        <location>
            <begin position="24"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="390" mass="44593" checksum="6C7DD8C6CE4B7B0C" modified="2022-08-03" version="1">MGGVYTKVQAIDSLRPGDHVCIWDYSRWPISYQHHGIILASGAVPAEVKVCHVWSPLEGYEEAQADSCFRVSTLEEFLYNRDEKHLRLVEYHTSGLREIMSRWGEVHLSKSDLPEVVLARCKYLLGLGRGDFNIFKQNCEHAAHWCMTGEQWCKQSLTKAKGRVPFENRVPKEAVDELYREIEEIQKLSRSVVDSVIKLSNTKVYLRVNGSHYVRILESGQVAVVPQGDDPATCGRTAFRLECYSKVYNCIKVSFYHEESQRYMFSRSTFSCFRDLRMKKAVFVRGKTGLQWEYSSLGNLKSMNQHRRYVGIRDDGLLVDVSMRGLAGRVEFVPCEPAQGTYEPPDIDKVTRKFDHQDLCSIQSRSMRDFEASMKSSDPAALPNIPPALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJZ9</accession>
    <name>A0A8K1CJZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJZ9"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="174" mass="19371" checksum="537792F16B771198" modified="2022-08-03" version="1">MPAYHSSFNELPAQEACGCAILPIKTRARGPAPPAPEGQDDIVDEIIQLFRANVLFTNYEIKGNADRVLIYGTLFVHLCLKKLDKCATKADAVRVLQQAAVDTFAIPGDSTFPLGGMVRAPTSANEAETIRGFLKQLREAIALRLPEEVYADGTRSKWWMLFSKRKFMNKELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK68</accession>
    <name>A0A8K1CK68_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerases I, II, and III subunit RPABC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK68"/>
    <dbReference type="OrthoDB" id="5585087at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.30:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerases II, IV and V subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7620" checksum="3EED60D07A886BD3" modified="2022-08-03" version="1">MDGGATPAPNAPGAGREAVTAAKDPEIKYICGDCGIVNYLSARDPIRCRACGYRIMYKARTKRLIQFEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL44</accession>
    <name>A0A8K1CL44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011586</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69300at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049052">
        <property type="entry name" value="nSTAND1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20703">
        <property type="entry name" value="nSTAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAM" evidence="7">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1321"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="1662"/>
            <end position="1708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1168"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1543"/>
            <end position="1574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1716" mass="192346" checksum="942E51D068DE5A46" modified="2022-08-03" version="1">MATDWAEWTTDDVCAWLERIGLGEHRQAFEENAITGDVLPDLTKDMLKDELGIAKLGPRLRIINGIKALTQPEEEKAPPVPPAPQSAPAALPPMVPVPQVTREANALDLVVLHAAPLIIKDREGRIFPMEKLDLAAERRAIVTSLVNEVLHKSIHLRFDVATADTLRSLMTAWKCKVLHFSGHGIGQRPALCFEDGVGCTHMITPDHLRQLTFSGSETPTPTPSTTNYLQLVFVNSCHSQKVASVFLDAGIPHVIAVHSDSLVVDASATMFAKHFYLSLFSGHTVRTAFNVAKGFVRASPMHKRAACCCAHLHEPNCQWMKDGSRHSHHNPKQCCCKGEHLPFPHDESSKFVLLGPDGRPDAHDVVLFGNVPNGKLVDHTPRCNSSIPSMHGQFIGRNSETYVLVRSLHQNAVTVCLGAPGIGKSSLVISVAHFVHSRRMFPDGVYYVDLEGQKVSTVRYAIAQSMGIPAADTDEEVFGELSSKRCLLVLDKAEELLDEDEGKTQELLEKLIAMAPNTRLLLASRRTLNISKVTPYCLSLLQLPLRTATELLCLLAQGCSLKHAKRLATICGCLPLAIRVVGRALANRTTLTPEQMIDYLERDEGRFDNIKELNQVGHKEGIDRCIRSSFCHLEEPLRLAFMALGFFRGTFDIAAVNAVLSAPRTEEEAREQTLRSNSSSPSSLFPAHFYARNTLRGRDDDTSSVNSLSSTLLSYDGYSIDNDGAMTSDGYDLLDLESSDEIRARAVNVTQAKDALRQLHQWSLVEYDSHEKRYRMHNLVQLFAEDEACRLGDQEFMEQNDPGSPKQPPGLDNDRIYVPLGKELLLAWKRRFVRYYCMIVAKASHDYRLEGTLVMFDKERPNIESAMRLAQELTVQSIDRVRELKIQRQRELFDSSATSVSDTVSTGDFSEFMSSSDSRNVRDSSIVDALLYTNLVARSRFIFRTRVEPKRRIQVLTACLQLSRETRSLNCSCGCSENDPSMLLWDIEEVKFERELTILDSLPSFEDRQAPIVLTGGCSCVGIRELIALEALILNDLGYAYCDATDWVAGEYYYLEALRLQREVLGWSEHAQVADILNQLGICLSTRWGFLAYNVWLLQHAEKLLKGSLAMRRRVLGETHSEYATSLNNLANFYRHCGPLKKKPPPSSKLTETVVDLNDARPIMSRSDNSIDLASDAGSDSVRSTQSSDHSTDDMDESEPDIESMYRRSLEIREKALGKNHPQVAQSLNNLALCLSGKLESKKLSSEEIETQRAEVGRLFQRALDIRRNKLGTSSFETASTLNNIGSYKRVLRDWAGAEKDIKEALEITERYFVGGSPRSARMYINLARVYKDQSRYSDAIDCFKKALEIRQQLFPDSREVGYCYEQIGKCMQQQGEKEEGKKIEEQGRQMRRVGLSAASEQQQLLSPTSRGDPASSHMFARVRVLDVVEPEALESRKFHLAGMLVGERGINLKRIEAISCAQLRYFGRWSSPSKDQLPQSEESYIQITYTSEQSLEKAKELCIALLRDIKAQWEQFVADGWLGATQRLGILMGVQCSCLQPRRKRPRRSSDDDPSIQDPFASRTDGDDDSDEEIGIVIDGMDERDGLLAPLKRGAKTAVGKDATMRRTSEEEVTTGLGTRLLGEEDVTPLGATEQRRNLDALRSYQQVTGIVDEGELDLECIMCLDTFSTEHPKVRSLCQCGMNRTNFHLSCLLEWMNRDANCPVCRQYLFYEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL71</accession>
    <name>A0A8K1CL71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein regulatory complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009165</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
            <location evidence="8">Cytoskeleton</location>
            <location evidence="8">Flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DRC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL71"/>
    <dbReference type="OrthoDB" id="7760980at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039505">
        <property type="entry name" value="DRC1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039750">
        <property type="entry name" value="DRC1/DRC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029440">
        <property type="entry name" value="DRC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625:SF0">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625">
        <property type="entry name" value="NYD-SP28 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14772">
        <property type="entry name" value="NYD-SP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14775">
        <property type="entry name" value="NYD-SP28_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein regulatory complex protein 1/2 N-terminal" evidence="14">
        <location>
            <begin position="78"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein regulatory complex protein 1 C-terminal" evidence="15">
        <location>
            <begin position="455"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="110"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="315"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW64998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="551" mass="65327" checksum="880002338D344DFA" modified="2022-08-03" version="1">MPGPRPRTSPRRNVMARMFHLSLKLRGGAQLGKAVKGRSKDGKGKKDGHETTEEERRLQDSIRRMEMNDYMKKLTLSKKALLKEFMAKEDKISRMNTLKIQNHWRKIMRLVKVEALRKEVEIRSQNHERDVDRKDAIIQMLDRDLEEAEEQFQMALRSHLLNIDEFIDLQDERLLGLEKEFEQDLRELEQEFLIEKEKIVTQHALEKNELQRIMNEVEQQEKEKEAETRQEHEQLREEIRNKNLEDINVLRITLDSMIEELEQHFETAHLNYLQNTDQRTQDFKYLTAKDQELSRDIELKIRKIERLQASIAHWRTKIAQNVKECTERNRALEEEKNAISGHFQKLKARMNRMRDENKRRLTELANNARDAKKTLDEQIELAERIIALGELVRKLETERERVLPFYHSTIADEREANELTENVRLAVRTEQVRDEEGENLIDFQSHGVLNGVAVSEWDYLDLFWKRYNKVLLDELAIQREKERYENENRELQAILKQYLDGISVNDNVMNNANPLLVVNGRLKLHQLEGVAQKSKPVIDANHMVATNRVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLM6</accession>
    <name>A0A8K1CLM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLM6"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF57">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="68"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="31674" checksum="C69F0F47B70D608D" modified="2022-08-03" version="1">MGQKGTGRRLSDQERMEIISKLEGDKPRASAAECARQYGVSSAAITKLMKMKDKIKQRFKENNAFSQQRKRGGTERHAVFEDELFEWINRQQAATGATQLSAAKIQEKAQELLKAHDLGSFRASKGWYYRFCRRYGLSRSSFGGDEVDQDDTMLGHSESEVDDPDTEEKLEVADHVASPALKPDEDDADKLTKKKRPHDATPKKLKQSSSRTWAGIESLQDTLARAANALDHPGARDYLGENAANEMLRSIQQSIGVVQCIRLKKLTGETPLTPAPSSPPTDVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLU0</accession>
    <name>A0A8K1CLU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLU0"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="266"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="581" mass="64583" checksum="95CEC477AB5C8F9A" modified="2022-08-03" version="1">MTIRKTTTTASASRATLRMPATAVAHTHGHGHRHAHNVVIVASPSRRTSLLQRQVSRALEIIELYDEHEDRLASAADGWRDVEDEETNDEDTSGRENASTANVAVHAARRLKQTSTMKRSGSGSLSMPSVFQISPNTIKRKRSHSMSSLTSGAKVDVQGLRVNIEQANHKRLAKVGNGRVTPSKRCSKDKKKKKQKVDVIERALKRFHADQTEDATRCFEFTGVCNRQFDDACSNRSETGFHRLSSSGSLDKTLDGEDQYKTMRVQVGVAAAQGARAYMEDRFSVTTRLFEDCEDDKLPSPASLLGVFDGHNGSMAAEYANDRFRELLSENDFLRDLCRRPPHEVLRAEEEEQIQEILRDAFAAVDEEVLDMTLGNNKRDGSTVLIGLLIAGKFFVANLGDTRGVWATRENEVQRVSVDHKPDLKVETKRIEEAGGKVIFSGCWRVAHDEVPLRLAVSRSLGDHPLKTNLPVSCSAPLVSVVPDIRIVDLTGQDDVIVFATDGLWDRLTDEDAIRITREQVASFCQQVSGDRNAMQHAANALVEHALHKRSMDNITAMVINFSTRSDSLDDVECDRSWAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMA3</accession>
    <name>A0A8K1CMA3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMA3"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF62">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="92"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="395" mass="45125" checksum="F295C2692B1AC28D" modified="2022-08-03" version="1">MHLEAGVKKDDDNKTLHRPQGNALHSNYYERWLKAIGFSLLAFWFVFVIVYWNISSDEPASAGRADVALDIPSRTNAVASGTFENAFPEETNFMVIGDYGTGSEDQVRVAQTLKMFAAAMEPKPSFVLSTGDQIYEHGIASADDPMLKPRFEKMYEHPDLRVPWYITIGNHDCEGSIDAMLEYARQKDSLWYMPRRYYKIDRPVAPKTILRMIVVDACDLVCGHEPRNVRCKDSMNKQSSEKTRVEQYQWIEEVLSAGMPAGIERMWTIVVGHWAVYSYAGNADTPELIRSLDPLLQKYKVHAYFNGHDHCMQHIKKVENGWTRNYFVSGAGGYKVHDLKPHARANPDLVHAAMVHGFMTVRMTKDLFRVQLVDKMGDILYAADVDYEAPWDKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CME2</accession>
    <name>A0A8K1CME2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003939</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CME2"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23279">
        <property type="entry name" value="beta-trefoil_MIR_SDF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431811" description="MIR domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="4">
        <location>
            <begin position="104"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="4">
        <location>
            <begin position="167"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="303" mass="33377" checksum="7B203A0A6E113AB5" modified="2022-08-03" version="1">MHRTSMPRVLAVGALLLALSGVQAHGKDAHCVRWRATAQCDPHGVREPHNDAACGQTIVKGLSGYCECENRRRVREVTCDHHEFTCEDACRQDASVELSYPQGFEYVTCGSSIKLVHETSRFRLHSHEIAYGSGSGQQSVTAHSARNDPNSYWLVKEADSASACSLGEKLQCGATIRLEHIQTRRNLHTHQFRAPLTQHHHEVSGFGVAGDGDAGDNWIVECEENQQCSAADKCEDDGLWKRGELVRLRSAATGHYLVTSARARFDDSNCPRCPINGQQQVSATTEKDELTFWSAGEGIYVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN05</accession>
    <name>A0A8K1CN05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN05"/>
    <dbReference type="OrthoDB" id="126716at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="316" mass="35040" checksum="7A1D227B80F4D76A" modified="2022-08-03" version="1">METTRGRKDAMRGDLSHLESVLQQLSKHEERTHRQSVERTSVQAQHRLLKDQLLSVQEELALAQGRKAELCETLGALQQAKEDQDKENRQLRVELQASREAQNTLLKKVAELETTTNQLKQQYIHSLTCRTKAANELLGKLHITGALGQLTDASIQTSPAQIKNLAGKPKHCVTCVKLQTSFDQVKQELAKELDAAKSSTSVLQEEHQQLKSAHEAILIGAEANAKALEETCAEVTQLQQKLNETKLKIPQTPVSDCAEPRDLADGEDMSEKVKVLEDNLAQLNTYADHLELIINQCASCAVKLQSEGTQDIDESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN35</accession>
    <name>A0A8K1CN35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Regulator of telomere elongation helicase 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_003693</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN35"/>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904430">
        <property type="term" value="P:negative regulation of t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010569">
        <property type="term" value="P:regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090657">
        <property type="term" value="P:telomeric loop disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17970">
        <property type="entry name" value="DEAHc_FancJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000431">
        <property type="entry name" value="Regulator of telomere elongation helicase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057498">
        <property type="entry name" value="Rtel1_ARCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF34">
        <property type="entry name" value="REGULATOR OF TELOMERE ELONGATION HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23109">
        <property type="entry name" value="ARCH_RTEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0862">Zinc</keyword>
    <keyword evidence="17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="7"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="1011"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="790"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00073810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW65928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1075" mass="119560" checksum="67BA07A6CE52B902" modified="2022-08-03" version="1">MVRLEICGLPVEFPFQPYDSQLIYMEKVVASLLSKQNAILESPTGTGKTLCLLCATLAWRQHVKKTMKKQAPASGSNLGYEVGSDGEEVAQEVDDQIPRIIYSSRTHSQLKQVIQELKNTAYKPRVAVLGSREHLCVNEKVSQLKGTRQNLACRSVVKNRRCGFKKGFDEIKARNKKVTLPIMDIEELVEHTKQKKVCPFFLSRTMLPDADIIFVPYNYLIDPLARRSIGISLENAVLIFDEAHNVESIASDAASYALSSNDIAGCVAEVQQFINALSEHRIVLPPNSTVSAESAQTLKALLLEIDKGLNAFPLSSSGGYTKPGEFIFDFFQQFNVNFDTCPLVLGMVEEIIEVMNQGDDQRTAASKLDALLSFVGTIFRNKDKHMAVAKNYRVHIQEIQERGSSKNPRLFNSSRQGKTRVFNYWCFHPGVSFEEIAANNVYNIVLTSGTLSPLETTIKELGIEFPVRLENNHVIDAEQVWVGVVGKGVTGKRLNSSYNFRSTEEYLVELGNTIVNFARLVPKGLLVFFPSYGILEESVGRWQKPTSKESTASIWDRLLQLKEIYVEPRDRLEFKIAVNEYDEAIKNNASGAIFFAVCRGKVSEGIDFSNDKGRAVVITGLPFPPTKDPKIVLKKSILDEAVVGPGELKLTGNHWYIQQASRAVNQAIGRVIRHRHDYGAIILCDERFALQQQQKCLSKWLQPYCRSYQGYGEAHIGLLRFFKGNQANQQAAITVTKKLEVTNGPPNTKFKPPIRRTEEVVKEKDAAHADFDSAGNGIGDGQSYVNPELLRQPPKPAPAPEKKPSMTPTYNKPVVPPRKRTLGSVLTSSRSAMVESTASIARPFVPPRVHIESTEATQVNVTETSTDANEGAPFSTSVNPVAAFPTVARSVLSPADVKRLYAIIRQLHSGENVDTIMKELCDLLREPDRQSLLELMPKVLNDGARERFVETATALGLNVHGDTVANIAVQSTTSARGSSGMASFFERLQQNKRRKQHGHEHAVAVVKDPQCVVCYEITRKAYASSCGHICCLPCWQKMEKDGFTACPMCKLPFKLDQLSLIRAAKTRDQQVAPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNA0</accession>
    <name>A0A8K1CNA0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNA0"/>
    <dbReference type="OrthoDB" id="150638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461354" description="Serine protease" evidence="2">
        <location>
            <begin position="19"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43189" checksum="55271E1DE3710542" modified="2022-08-03" version="1">MMRLGFLALACSMGAVHAATSPVTSLLDQLKGQIVGNSIAITNGTLTTCEPKQWTYYKRSAPYLSVHFKHFSLGDDDVLTISSPDGNETHKIDPPDGVTTFSSSRVPGPTAVITFTPGSCSPDNFGLEIDVLEYTFGDTVMKEDVCGGANQNVAAVCYKNREGVDPKVYTSSFAVARLIKTDPDGPRSACTGWLLGSQGHLMTNHHCIKDADEANRTNFEFMVQSPTCDNSCKSLGDCRDYGKEESIGSDFIYANEKYDYAIVKLRKKPCLLNGKYGYFSLRRAEPVEKEPIYMVQHPNGGGKMITFEQDIDNTGSGASNSGTMPAIVEVVNDENELGDFWTSYFADTEPGSSGSPVVSATSHQVIALHSNGACKNSGAPSHLIIKDIEANNLGLPADAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNI3</accession>
    <name>A0A8K1CNI3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6818 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNI3"/>
    <dbReference type="OrthoDB" id="128122at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049203">
        <property type="entry name" value="DUF6818"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34409:SF1">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34409">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20681">
        <property type="entry name" value="DUF6818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6818" evidence="2">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41065" checksum="8A6548609FB07FA9" modified="2022-08-03" version="1">MAGDAQSNTKRDAIMNDASSTPSNKVLVSLFYEEPSPENPHHRRCLVCGEKKARSFTTGYRNLVRHLNRVHEGYLEVAERCLATGQTKATRAMFMDTSEVAVTPPEGTSIKDASVQYKAPVRRGGGRGGGTQAYNADDIDALLTCVEDLLPCTADMWNQVQTRYNETYAKPNGRTKRSMTSMRVKFSTFLVSETPVDDPNCPSEVRRAREIKQKLQVARGSRPKAAGPTIKRATADKQLGTVSSDDETLPDDDLATYAAEYDSDYIPERSQVRVPKPKRPRLRKTSAPSQDLHKSLAARVSAMENEFLALRNEFKSIYEVALRTNASVKKEMTRTDVLLDAFVQYKRSMLRQQANSTGQEASEGTLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNM1</accession>
    <name>A0A8K1CNM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNM1"/>
    <dbReference type="OrthoDB" id="193965at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040283">
        <property type="entry name" value="DDB_G0292058-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31414">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0292058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31414:SF18">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453164" evidence="2">
        <location>
            <begin position="31"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="715"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="764" mass="82989" checksum="1EBDC3642138D078" modified="2022-08-03" version="1">MTRSPRTRLLAVVALGLCLIHAVLVPQVQAVPQSWDNNYFRGEQSRSLAAFSSPLEQPYAIARRLDTMGDAQNKAAEVGASVRKAIKQLRRGTNKTYTEIIVAIRVYALDEDPPADMPMTNAEAEAKLKKWVQDLGVFIVPGIILAVLGLLTLIFFIMCRCCCNRCGGRSPKEGGYTCMQKFLPVLFFLLFGIAVVVVAGVAFLYQKTLTNGFTDLLDATSGTLVNTTNQMVAARKPLQAMSAKVVSVSGEVQSKLAGTDFIETGLTGITTRLDTYALYTADRNVPDQCTPVAVDKCYHCIACSSLTDNVNAASDEIETNAGSGVAELKKARTAINEQLVSQATTIKNTIDDKVTLVTDLEGTIGGLDGDVKDTQKQYDSIDFLPKIIVPALFGLGLAAVAIGLIGVLFGLTPLKCLANIIHIGYFIGFIALIITFLLSSVLLGVSVLLGDVCEITAILTEDWSLAVGDQAKFLNACFRNESLIATLNLEEYLEFARGGIPFPDLELDKMLDFTKLYDFATDAKALTTDTTFNLDPNDVDASITSLNELTSQNIAGAGNCHPHVSYTIVNVLEPWTVTATARSPSDQTPENYIKNYYDDYDTPCSSGSNGAVAFTCSSGSFCSYSDAVVERFNLAYVYAQVFKYNVGFGTNIDTVTTYTTGFKTDIRNFDQTIKDIKADLDSTLIGYANEFEKQMYCTVVADGFYQMFGVLCGDLLTAFTMIALMLFLAGVFLFPVNICLIIACKRLKARGSGGHVMDNEMKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNX2</accession>
    <name>A0A8K1CNX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WSCD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNX2"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF5">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="110"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="431" mass="49361" checksum="5E238F3B5A2FA63E" modified="2022-08-03" version="1">MQAVLHGALFLIKAYLQLVLYVPRVLIELNLAWNPFFIIARKLFQRAFLTMEPASTSTKVPVPAATGSQSEDETVPLDVEEVAEAVAEGIAPVPKSEMRWLEPGEYNGEHIAIVSYPRSGNSLMRGLLEKVTGVYTGCDTRPDRTLSQQLQEFGMKGEGIVDDSVWFVKTHFPERVGWKSFNIQKAILVVRNPWDAIDSYFNMTLTNSHNKSLHESQYERFADRWDGMLRNEIEVWMKFHRYWTSKVDIPIIVVRYEDLLIHRAETLRRVFLFLTDRPSIEGTEWETRIKNVMETSGENSGPYVPRSGKIGASFKHYSDEQFQHILKVANLPLRGFGYDPVTQNFPNDIQLPRRQVKPGKTPDAVLEVPIDPAQEIRKRNDAYGRYSTWYRKGLTDPVIANDGTELNMDEVLQARQKAEEDKAKAENRNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNZ7</accession>
    <name>A0A8K1CNZ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_004158</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNZ7"/>
    <dbReference type="OrthoDB" id="69720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="125"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="332"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="14">
        <location>
            <begin position="480"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="910"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1085"/>
            <end position="1113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW66393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1184" mass="132924" checksum="587041E30388C85E" modified="2022-08-03" version="1">MMNDASFVAMTSPMGRRAHSLIELSSNVERLETASQVDRALCMDSSVSENERMTGDGHRVQFNGVARKSDRSSHVSRSDMGRSLAHVYEPTLQERAQHFLEGPSGLYLELVNFAFSVLIFALYIAELYHPNLGGLVTKRAIELTLTSFFILDLGLHLFVAPRPLQYLFSIYGMIDVITIIPSFFIFFVTRTKSQAFFVLRVLRIFRSLRVLRLKRFIKFKRHGFNYELSVFLLSSIAVILCAAGLYHAMEEPHYLNDNGAFRFHEALYFILVTISTIGYGDISPQTSLGQVFVMLLIIAVFTIVPQKAAKLNDLAKLNHAYDGDYTRRDSRSGHVIVSGYELRMDSILDFLDEFYHCSRGNIHLDVVFMCEAPPSPEVTRLLATDRNAIRTRYLRGSLSNAIDQQRARLGESTAVFFLANKLFRSYSAQQDAAMLLHTLSVRNFADSSGKCLDIYLQLRSHDPELEMTSQLLGGNTTNTSELRTMILARATTCPGASTLILNLLQSVSTAEYMKSYQGSKLWIEEYVDGMSFQLFPIIFTKKFQYEKYDDVVRNIYERYNALLITIRPRRSGRSSGEEEMEDPELRIAPFQTTIRVGDVGIVLAKTASDVLHIATSYGYWSEEMGCRVTTSQLVRPVRVSSDSLIKRPTNSFWSSDSWSIPVMDAYSTSIRRSVAMATNPSPMARSPRTSLGKTDEIISATTPPSIVMMPIIEAVRTKQIDLVQKILEKDHFIFDGKHLEGHFVVCAGRLRETLSIVAFIKHFCALEQRVRPGVVAALASIHVGSVPRYNSDPTCVLLVENLPKAEKLAQVLKRIEEKGEDISSLMQNVLFLEGNAAKVCDLGNAGIQSARRVLLMPSQAEAARFKFNPTSPDPSSATRHVTTPRYESLADFGVINSLLVAEVVRDELSSQSSGRFSPRRRQSSRQHLNGENSESALDFYRRQEEQGIPLESIKLRMLERFPDMDPRAFDDGDDMIGDALQLYDQSHSQPDDGGIMDANRDRDGADDLDGLNMIAMLHHASSARFCRPQDPAVCHDEFPYLSPSFASGNVFLSSVLDRVICQAFYNPYITDVVRALAVGHDPTTTFPTIDETRPEQSQNPGAARKPSGGSSQNTSRRLFQVVVHESYVGSTFFNAFQDFLSINMLVIGLLRYPSPVLENFRPYVYTCPAPETTLHSNDRFFVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP76</accession>
    <name>A0A8K1CP76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP76"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="649" mass="71962" checksum="D95E024B19967CD2" modified="2022-08-03" version="1">MMNVAGNGAATPATAALASAPSLQEKQKENLLRMLDFNAEASDSTLDSADRWGDQWKVLIYDRFCRDIISPILKLHELRKKGVTLHMLIDSERDAIPDVPAIYFVEPTPANIQQIIADCSKELYATVHLNFAYPLSREALEMLAKLAVERGCTSMISKVYDQYTNFVSLEPSLYSLNLPQSYRAYNDPTMADTQIEQSMTSIVRGLFSVLATTGKVPVIRCPNNQGPSRMVAEQLNQMIRDYLTARKGVFADANSSFQRPVLIIMDRNEDLPSSLHHPSTYQALVDDILKISLNRVKVNVKTSGDEAGNGSRNVEKIYDLDVTSDRFFELHAGSLFPDAIDANEEEMKQVTKKEEQIRAKTGGNEALLNGTKDLVAAVDTLPALLEKKKMLEVHTNIFHAAFEGVTARHIPSYSMLEQKLFDGSHVDKQEVLQLLSGPETGTLADKMRLLMIYYLTSGATTAEIAEFEHAFQQFASTSPAGDQYARAWNFIKKHTAFQKHANVGGALQTEGQTPPGTTAGSVNINKFKGLAQGFLAQAAASVKNFLPENKKLHITRVTDAICDLRPNTEDDSFLYLDPKIKSVGDGNVPRQRTPFREALVFVIGGGNYNEYQNLMTYAKAQQPPRSVWYGCTELLSPEEFLEQLGSISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQQ7</accession>
    <name>A0A8K1CQQ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007467</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQQ7"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="407"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="804" mass="87143" checksum="DF6912133794E167" modified="2022-08-03" version="1">MRRSIGELSYETRGGTGGPLEQPLGRGQVVVPATDNDVLDDDEEEEAEVFEVELGGGSSPWATALLECASEGNLETVKVLLDEGKVELDDVDVDGFTALMIAAAEGRTHVAMELLRRGADVSVRTHEMRSTALHFAAKSGVAEVVEAICTRDPQSIDCQNFDGDTPLVWACTEGRVDAVRVLVKYNADVNVVSHRAMSTLICTVMLRDEDDGGSDADRAAILRVLLTKNRKLVNYQDRDGSTAMHLAASHGYLECVKALLEFGADITLRNAIGQTPLEEAQDTGVPECAPCIDYLRDIWKRLEEEAAARMMSMLEMEESLASSNPSNGSSRGKKSKKKQKKAKRKAAKSTNALDSATTAPPTEATSSGDESSGDERGDKVAFGVQTASQDAPLVQLAVDEAKDDTGAWTTVGRKQKVTEAPKTESEAPAIDDLSQPSSEKRSPHTKVVPVVAPVRTPPKSVPQADIQVSTKSTPAAPNATSPTIPPAPTPAVPPFPESVGSPFSTFQTISHSSRLYERYAMPQAPAIDRLRGFTGGSVTWRGSSELSSLPNSPSLTAEASTTPLPSLSSASIWKHASSMPSERLSRPSVRSNSTIGATRRRWTHDRIQRSSESVQEVLEFLACGICGELVNDNVQCGSSQQCPQLYCAACLMRAMSVSPAGFKCTRCHHVVDPKTVQRNEFAQAQAAALGLASRSHSRDDEQPQRSLAEMKRHMDMTSEKAVCVDLDPFHLAPGADLTTLSNGQLDVLEEMHEMALRHIMATRLEIARAQERLRIEEWLKTRRDLLQFTSPPSAMMSEQSLQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQQ8</accession>
    <name>A0A8K1CQQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQQ8"/>
    <dbReference type="OrthoDB" id="127244at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="364" mass="41420" checksum="34F4F099C736042E" modified="2022-08-03" version="1">MGIGKMKSHRTSSESDNDSVHLVAPRPLKKRRNTYDSRKDEVLALRKEAEYLTLKLKQIQCAMLPGMLRLQASLHQNMMLKLQIKEMNEALGAAQCMFANDQMLRNRNPLNSFIHLPADSMERRQLLLSMKEQKLFAAKRFVEERISGLDLYRSRQQSESYDTEEGDRILVQCDVIPFHGATSVKQVYDESLVALGLMEFSLWEHLGVTAISESDDFSDHVPVSQHRVLSTTVDGIDVEKNMTTFKSFVEADPESDASSYGLITLDSVDQDDLYPYQTHTRVRKDLSAVVLICRSPPKPGREPTVSVVRYGYARLHQSQCGLATDKESRLIESMPRWGEVIRSVLNEYVSNRLQYPQMSPISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQS7</accession>
    <name>A0A8K1CQS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein S-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012055</name>
        <name evidence="8" type="ORF">Poli38472_012058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQS7"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="29717" checksum="78346C2F01EB8946" modified="2022-08-03" version="1">MVVTGSVVLAKPQKEPAFSKKHEPSGLSTLFKPQPEMIMGVWAAWVILFIFFHVVVWVDPVYKFVVTDWEPFLYTLVGIEAVFLLTWFRLATVCPSDPGVIRTFQVDITQMLANAATGVVPPEASYCRTCMIRKPIRSKHCAQCGVPLVADHLLALMVFLWGIGTVIGLSFMAVQHLGNMARNLTVNESINWRRYPYLKADPKNNSKAADKLPRLLNPFDKGGWHNTLEFWTRSGSSALDYRTVFRLPNAVDEPEEPIINVQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQW0</accession>
    <name>A0A8K1CQW0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQW0"/>
    <dbReference type="OrthoDB" id="72790at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="335" mass="37129" checksum="30F8F5B5F9E9CD2B" modified="2022-08-03" version="1">MDSVMPLVAREHDVTTEIKGEDAAMELALAEEELLQGGDGEEEDDDEDVWDDDFGEKEGEDEAPVRPSLHLVTSLSEENRRCMEDWADNDEDEDNWKDALQARVNQLELVVPSKSETSMLVASTKEEPMYATPVDQRATLTLVPMMAPITRSTSAPAAAETTRIPKAGCKPHQRTKETTTSKSATGAGSQTQARKRSNSRDYLTRTPSGSGAEILRPIKALHTDTAHARPGASSNVFVRAVVARGNNAQRSTSSEKRGTAVKHEEDPFAMPSDEMLALSDAEMIRRFVLHDVKKMSIERIVADAKRLQYLEDVHRRHHSVSEDTTHTARLIKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC6</accession>
    <name>A0A8K1CRC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC6"/>
    <dbReference type="OrthoDB" id="164695at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="155"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="427" mass="46894" checksum="7664D701B211F66D" modified="2022-08-03" version="1">MASSGSGVANMTRLLQVRPYGDGSGSYPDVGTGLRPGVPTLAPWNSSVTPTPTEHPTNSTSPTQLVIIIVTIVIGVVIIGIAIFATIVWYRRIRKRHPRPSDAPPVFKAKSTSRATDTTSSTPRGPGAGPKTTQLTGSLWNDEELLSYHMRIDDLQDVRIVGSGGHGIVYLVKYRDSRLLASKRLVRDQLTRQKSKALLAEIKLVAKLQHPSIVEFVGAAWTTETDLQALFEYMPNGDLRSYLDKTPQAPWDQQKELIAADIVEALVYVHSFSPPLVHRDLKSRNVLLTEDMHAKLSDFGVSRYQSDNRTMTGGVGTSRWLAPEVISASGEYNHMCDIYSFGVLLSELDTHIIPFSDLRSPQGNPYPEVGILQLVSQGKLQPSFSESCPEYLVTLAKRCISFDPSLRPSAIEIAYVLRTAGNAAFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRI4</accession>
    <name>A0A8K1CRI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRI4"/>
    <dbReference type="OrthoDB" id="157595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="33159" checksum="3CD572C1E0B64FB3" modified="2022-08-03" version="1">MSSNAKKVIIVTGGTTGIGLECGRALAKYDNVHVIITGRNKQRVDNAITEMKQTAAASSIVEGSIMDNANLKSVRDFANSIRDRDLQLFSIVGNAGIQATKKELSADGFESTMATNHIGHFLLVKLLLGRTKRVVMVSSETHDPAEKTPAPAPDMSDLDQLAFGREKFHGMGTYGESKLCNMLHVKEIARSHRKEALAYSPGFTPDTEFLRPHPRIFAALFKFFARLIFPLLLGIRVNSAKSAGEFLALMATADSIAANGWRNGDYILVDMVHKESEQARDPVLAKQLWDKSEEWVKPFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS51</accession>
    <name>A0A8K1CS51_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RAVE complex protein Rav1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="3">
        <location>
            <begin position="842"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="2062"/>
            <end position="2095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1623"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1831"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1623"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1840"/>
            <end position="1852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2171" mass="240824" checksum="DB7F021CD0E350DF" modified="2022-08-03" version="1">MVAVASPALLPSEVSRRRFCTATFDGTRYMFYAVDTFLVILSENHEQAIHNNPRSEAKRCSQFDLRQVWSVQAKVNCVAFNPIGKRVARGAVALCIDDKRIVLLTPTGAPTTTPVAAAAATAMASKLAVKTSDADLQPVSKRRPSVFTGRTSTDVSNEYAKVHLYLQLPTWKESIRWRSEDQHLDRVKWVESGDDLLLVGAGEKISVWKIVEESGLQAYLQHSFNIGEPEHRIWHFDVTHTGRYVASAREHDRILKVWSIGELAHDGKPISLFLPHQRALVSVQWAKNWHSYKIRHHDPLMPRVEMLYALDKNGDISIWREHVASSHRSFVLWRRFTTQDFLLSSSCTVDSERVDDGSLQHVLASRLRSFGLVQNNWGRPTPRAPMTITDALLERNTVLSALSLFHYGYASIDEVRRNELTNQRMDGIGKIHSKLLGDRRGMIADTHSGETLLNGNTPLNKTFVVTLAYAVHENGDFSLFRVESVHFSAVAPRVALLCVFSGLREQLVDATVYSICSSDYKDRENGSSTFIVEIVFQPQREERHAKIARLKFQAESTVFGARDSRAMASYSVQISIGVIQLDSTSIEGSWKLGWSSSRFDIKPRGLSSMQAYPNALVALDAGIARLDLKDFSQFVTPESSQTVLSGVIANAVHPLTLLFLLMRGSFKSLDQIVVHIRKSIVEHEKTCYLKMTENADLRNLPLLELENLFGKPVNTTQEDERPLAYRNGKGASQGTAAAAVSSAPARASDLFAMDFGSSRRFGRDRAEDLFAPRVPAISSDSTSSTEASQVPDKLELESDGLLAFFDEHKGFLAFVPDSYRPVFLNIIKNAKKIIQWERNTGKAKDEAALRFITSLMWPYKSSDVGPKNSVELESADASDSSPSGICSEQIAWAAVSDCQAELLEECFPPTMTLSMKDLTQLRLPFWVKSATRLTQYAEKVAQAEYASTRDPFRVALLYVLLGKIKLLSNLFNMGNEKKIAELLRNDFSDERWKIAAVKNAYVLKAKCRYELSATFFLLGGKVQEAMSVIENEDPSLVLSFLIARLSEKWDLGGQGDESGGYNAFNDASFTGLSTSLRSFGADGGRTGSNCKDVCKEYLKTTVFEKAQRCGDIYMCFLVKYYIGETANAIQCLLTVPKVEMRCVFDGPPSTGSQLGDSRLYWGVFGQSLLGAIDLVRFLRPIIRPLSTSIKTQMVRTQALTLNRLVGSGWNVMALYQQQDFAEQFKQFCRDNASDSSLRGTFLSIRNRILCNIISEQTVSLAISTAKRISQSLNQRASFESSLPIEQRLKAEIMCLIRRSGAFSIDEIEKSKDDTVEQALRSAVVETLSHSDQNYLLDFILQEWSSKDPARSPMSNPLPQLIEKIVDNLSWIASGDLTTLGTTHFHSRRIDQLCSELLTSAESLLCWLAYYFAKPTEERSVFHSSAEYIRVISASVYSIICVCCRYIKSPCCLHRALTAIFPHMDSLPKKILDEIKEISLADVCANCSTSRVGADAEASAGPPLPSLQQDISVLYQVIQMLQRDLNLFVEEVRTNRLDLMPPAASQFTYCQYWTLSVMLAVSGMPTHISRVAVDGANPHALSTTLAKRLVQTWITHNANMSKYATRLLLCELIESYFRPFDLQRPSTPTGASSKDNSGGTPTISPTAAGMANVISPNHRDRRESRQLLRCSCDRCPWLLILKIFADKDELLLRINSQLECCSEKIKEDISWGHLPDFPSKKSVFTRSQKILLSSAGAGKAAEITDLLERRFQHSTPAITVSTNCIYRSEVSIKSLCFNQSTETGEMVLCSSKGICRAASVEYSDGTKYQFKGMYANPQAAFFSDTNAGTSGIPVSRRRSADTSLMSRGTTDSPQKGLDSPSLLSATGLSEMKTPSFKPSAVESHPFLPLFVSGNQKGKIHLWSYESLSSVCEFQTKEVVTTYQLSPATSSRRDIKRLQFDSLGQQMGAVDTFGRLFMWKFANLEREACYREIECHDKGAKALKFINSGTIVATVGTSTDKRSMCMWDLLLPSSKALIAAPTCHPAGAASLAFSQAHQLVISGGEGGSISVFDVRQRRVLHTISNAHETAITTLELHPSGRCVLSGSASGDVKIWSLPIFRELVSVSKVHAKPSFLGDAASNLLGDAASNMAINVTNSSWGVTDAVATDDYFFTSGTDGSVQRFKVPSFDKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG3</accession>
    <name>A0A8K1CSG3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007567</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="838"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="862"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="945"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="94"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="411"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="721"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1041"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="657"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW67895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1290" mass="143763" checksum="A34BB4D3F7779CB9" modified="2022-08-03" version="1">MKSYATFDKVGLDEAHPHPYTQASWLSRALLSWVTPLLKLGHQKRLESDDFWPLQHEHQAKVISDSFTQDYSRSHSLSVSFFRLFGWRFLLTNVAFFLVTAGTLAGPFVLHQVVTALSTGDYDVQALVTMVFGLFGAQVVQALAENYALFETAVINMQLATAIKHTIYVKSLKLSNVSRREKTLGEIASLCTSDCGTITHVVTYLYQTWLIPLQIVIVCVVLYQLLGIASFAGFAVIIAALNINRFITARMCVFYVAWVTSKDSRMRRVVEAFKSISIVKLNAWEDKFRERIGGERAREVSSIWWYLTFNASSVVMLWGLPVFVSIVTFSVSTALLNQPLTPATVFTSITLFQLIQVPLRDVTLVVTNIIKARVAEDRIQSFLEMPELDENAVNSMEHRNPSQHHQQNVVIAIQNATFGWDTDSSVLRNVNFKVHTGEFVVIHGPVGCGKSSLCAALLGDMNKTSGNACVEGSVAYCSQQAWIQHMTVRDNILFGRPYDRKKYEKVLEACALTKDLRSLPAGDRTEIGERGVNLSGGQKARVALARACYSDASVFILDAPLSAVDAIVQNEIFHKCFLGLLRNRTIILVTHNPEIIGSEHVTMTVTIDGKGELVETRSKQTRPQHDSIISPLAEHEYTKSRFEDDFQASQSSLRVNTELLGADPSRNSASPPTRSRISPPEQDPVAEEHALVKQEERGDGRVGFRVFMAYYRAIGGFPVVLLVFGTQLMGQGFQVASDFWLGQWSSAASSEDAFSTDYRIGIYTLLGLSAVLMIVIRTLVFSWSCIRASTTLFDRMTYALMHAPLRFFDANPIGRILTRYSTDVATVDMTIPQRLNRFLGNLVILLFTMGTTAVIIQWRSVFLLPVVIIYVQVGSFYLEPARDIERIQKTADAPVLSHLSESIEGAAVIRAFGSHQVRRFHCMNDAKIDATNQVTYTQLCVSQWFALRIQLLGSMLGVIVTYSLVLLRDQLSAAIVGLAFSYVLKFSHSMERIVSSWSSVETIMVSPERMQQYIDIEQEAPHKIPTFDPPASTAWPSAGAIRFENVSFRYKDADQLVLKNLSFSVQGGEKIGIVGRTGAGKSSLTMALFRINELAGGSVLIDGVDVGKIGLKTLREKLSIIPQNPVLFKGPLRRYLDPFSEYSDDALWSSLRRVGLSDRITSEDDKLECMVEENGENFSVGERQMLCMCRALLRESRIVIFDEATAAIDHETDQKLQRVIREAFVGSTVLTIAHRLDTILDADRILVLDGGEVVSFACPSALVSAGSGHFYDLMREGGYLNKFKEQTKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSS7</accession>
    <name>A0A8K1CSS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSS7"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035489108" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="4">
        <location>
            <begin position="90"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="335" mass="37794" checksum="51C97E2A99B51CFF" modified="2022-08-03" version="1">MNHLRVFWVVVMITLSTVMAEAIAPCSVGGIQFTGLLQYLAGQYRIPGSIYADCVDGQPICYEDDGISDTTDRVISCDNVNLESRRRRLGVYIDQNFTWPNRVVCVNWTQPFSKETHVAFDKAIKEYYQMTDITFIDVNLCRRSYGKKTAVCDDCRTAVKIQRSEKGCFATVGHINSMDRILNLAQSCARYDTVLHELGHVVGLSHEHSHPQRTVIVLRNKISATKSNYLKRPDFETTDYDPNSIMHYNGKALCIPRDPTINFCDINETKADGCVVPKEEHCDRSKQKLFGQGKDLTAGDITTVRKLYMGIERPGRPQSLLRSASQSSPIEQQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CST7</accession>
    <name>A0A8K1CST7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007747</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CST7"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000295">
        <property type="entry name" value="Glutathione S-transferase unclassified 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051369">
        <property type="entry name" value="GST_Theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917:SF8">
        <property type="entry name" value="GH16740P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25549" checksum="2AD3FEFC3F215AF9" modified="2022-08-03" version="1">MSLKLYANLISQPSRAVAWLLTVKNVDFELVRMDFGSPLFKSEEFLAINPNGLIPVLKDGDFTLFEGNAILTYLADKYGWEDVYPKDLQTRAKINEYLHWHHTNVRKFTPQIVAPYIHKATNAASEEDLEYIKNAPELIVKYTTLVEKFFVTDFVARTSEPTVADYALYCEYDQLESLGLLDLSKFPKTAAWFGRMKKVSKHDELREEMNGAFKHLGIFARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTN2</accession>
    <name>A0A8K1CTN2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTN2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="93" mass="9796" checksum="B3FAAF9D49A6BD92" modified="2022-08-03" version="1">MRVAHRGLYSSIIEANSTDSSTTSSGDDSCSQPELVEGCLVDVSCQTCLLRAGCAIETSTGNSSTGASCKCHVKRVWNARAVQLNQQLANVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTZ6</accession>
    <name>A0A8K1CTZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal eL28/Mak16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTZ6"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="4">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="139" mass="15583" checksum="382285CE6DDAEAE9" modified="2022-08-03" version="1">MSSDTLTWLLTKNTSSFLVKRSGNEFAKEKFNLKNFNSAKFSGFANTKAVDISLDDKKVTLTTKIAKAVRKPVKAENVVPLRKGARAGGNTIRANISRNFYRRDLKKAALARWSRLSTVAKVEKGVLQKKAIRNRRIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUJ0</accession>
    <name>A0A8K1CUJ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUJ0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="12569" checksum="A5A0B65CC60A38C2" modified="2022-08-03" version="1">MVTASIAPAPDLTSDASPRTFQPTLTAKKLRHLWFVVFIVQLLYTFQLVMMADMYIRTSWRAFVPFLTFLTETFLVTNERRFITHYATLIGASYAMLATCFTGLLFRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F993</accession>
    <name>A0A8K1F993_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F993"/>
    <dbReference type="OrthoDB" id="444255at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW54990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="31115" checksum="4E9BFB0C9A5F8405" modified="2022-08-03" version="1">MQMRAASLRAKWPWTRAAMLSLLWTSLLWLVVASNARLLLQLMLQSSHSSFSLRGASLMTRRCSPIRIDTTTLPTATKSRWTQELQSVRLPPSPVFQDDRHVLCDATNADQLAWGYCLPLGHLQTPTTCEKADRMGLLQGKRPVCRASVQHMLLVDVYDALETLAFSPALLSNATNATTDTSRVSYVESNATHHMTQTLRARGYHVFQDDDWRVCVAPTHPLAGLLYDPTKTIPVDSRSTPHIQLLQRTPSESQELLPLQLHGDTLLAMPSASSSSTSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9Z6</accession>
    <name>A0A8K1F9Z6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010622</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9Z6"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="79"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="476" mass="51995" checksum="7EBA868D0950697E" modified="2022-08-03" version="1">MATYGTSDHQPLPSYSPSARNSLTRSFGNTSTAPGWPVTFEAGVETVLQSPATSRRDSHDAFAEHSHILKTESGHGRGTSTFREAVFNSINVLLGVGVLSSPFAMRSSGWLIGVPLFLFFVLVTNHTGKLLGKCLEYQEGMMTYPDIGEAAFGTRGRKLISVMFFAELFTVCVLFDILIGDTLAALLPAYTPSQLMVAGFVVVMPTLWTAHLSMLSWFSLLGIISSFFCLYAIFFVGFAIDYEAPDYTMGSLLRPQPTELIADADRIPLAIGMTMVAFGDHSVFPSICSSMQNRADFPAVLDIAYVVTSLVYGAIEVGGYLMFGNSSAEEITLNLVDVYPGTLMTLMIWMVAFNPMSKVPITIHPVALAIEELLFTPQELHHATYRVKFYRALVRTTIGVLALLCALYIPSFARLTSFLGAFFAMFASVFFPCVCYLKLFGHRLNRGAKILNASLAVISVFLTIVGTISSFVSPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBF6</accession>
    <name>A0A8K1FBF6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBF6"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF36">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="538"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="69182" checksum="E7890B3EAE6615BE" modified="2022-08-03" version="1">MTSGALQMPQKRTEDTQQPQDEACRLEMAGDVACDAELMQTQMAAFVHEELLDSAQVLGELLMALANASVDVQQKNEMLASREFHAKSCRLFGDLLMKKREFKRAIQYYKRFWKLHVGSTAAALHPDAVQVKVKMAKCWMELESPQQAVEVLKSVPAVSRTLSVNLLLGKLYLLDGLAAKAEEAYLAALQLNPYAVEASMALADIQASREASALLSSASSSNPSVVDGVANVLFWERHVERFAPAARPQSSSTISPEVDAKWLQALATAHIHTARGRYRAAMECFDAIEKVFPNNLHCLLHKGKLEMDQDFHHQAHLNFHRARQVDDLNLALMDAHADCLRKNDARVQLNNLVHDLFAISEQHVEPWLAAAYFSEMKGEYDTALQLCERAIITNRHYAPAYLFRGSLLLQMQRPDHALMAFTTSCKLNKTLEAYGGVIMSYCDLCMKGLNKYKEALTTAKTVVKLYPQKSQSYTLLGNVLALRPEHTEQARKAFQRALSMEPRKLAAVFGLVDLLVRDSHFAQAIDKLVNVAEQFAREEVFTKLADVYTLNKQYGEAMTYYHRSLSLNPASADAARGMERLEKIMRGEDPDELNTTMEHMDQDEQEDSMEAGEYGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCK2</accession>
    <name>A0A8K1FCK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIH1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCK2"/>
    <dbReference type="OrthoDB" id="545063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="53632" checksum="CA294A8F9A77023B" modified="2022-08-03" version="1">MNFGIINNRRPVKAREGGNISNPLFNDARLREIAKQMGLDSKDFGKEAANLWKMLDEMAENDPKAYQEFIHEQIKDGPPMAASTNETGTPSASPRYFDPLPGCVVKCTMVDVQQQEQKLFVNLCAHEIVDMPKNPNSDRDVPRDTRAVPHTSNLQIPLVIGSLRKIHDVSGAACHAVDVVFHPWVLERCEWDANFKREVLKLAIEWIQQDAKIKLTTPTGKFIKSRYKGGLNVGDEIITAKFLIDPETQAKPGSNQIGQRPLSTEKPVVAKLATESPTDLLKEISLRDSDERIPKDEFIIALAGEKKAQQCDSKPQVCQDEVKHVPRPISKKLIEVIEPMQDNQKEHMQKKKPSSVVKKGFLNSSKTSLYPKGSNEGKPASAYVNLLSRSKVVDMNEMQQQRKKTVTDEFQFLKPQTSADRKSTDGEIDHGDHEFEQLCMDADPDLKPRHGSEDKTSTEQLFGDHIDEFAKFLTSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD45</accession>
    <name>A0A8K1FD45_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD45"/>
    <dbReference type="OrthoDB" id="192312at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="492"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="731" mass="78802" checksum="2A229B22E88F8990" modified="2022-08-03" version="1">MMRDICARFKYSEQDEAMTSTAVATPTNASATRASALDTAQAAASQEPALPLENAAVEAKAESPDEPSTPRTPLPLPTPTPVDCPPRELIHKSLRRYHRDMESGSADLATVEKRIQDDLAPYSVLKLGGFSLGNVAPKLLGAVLINSDKLRTLDLGFNRITDRGATILAQALEQNASLESLYLSGNDIGATGAAAIATALTKNHTLQSLHLSGNNIGEDGAKELAEGLKRNTGLRSLYIGTNGIGSKGMQCLAEALQVNRTLEELTLGQNKVGSEGLKHLATAFAAGNVRLTTLEIGKNGIESDGVLALAKALCAASNRLQNLYVDNNPIGDVGASAFGALLAKNAVLRVLDLSYTQMSLLGLRELSMGLSYSSSLLCLLLDGHDWASTQYMKKTNGLTGMSLSAKGANNFAASCIIGAINTNAKSVLFKLTGVDLTLVLGSLPLSASERDALVSQLYRASDPNGGPRRPIDLLARNERVLKFLQTQRLNIANHKRKSVESDERRQQEDKETAEPQAQRQRTTAAPYQQLSVRTDAQSTQPVTPSPPGAAAFSHPSGIPTRPGIVRHPLPRPPSSSAEKRLSIKSPRYESTMEVQVRKVITDLAKLPFNGDEYASLQTYYLGGCTSPKVHEARENFEENNTVREPAPEKATEQVPCPACRSSRLARYPRTMVLKAEMETHPGPDARILTLLRQLHYLTSVFQHVEHAEQKIDAILTSLHGGRQPSPEPRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDK6</accession>
    <name>A0A8K1FDK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-coumarate--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002939</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDK6"/>
    <dbReference type="OrthoDB" id="16262at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="52"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="464"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="61451" checksum="79F19816EB7D3A41" modified="2022-08-03" version="1">MLLRRSLSIARSQRLPRVGLHAVGATRSFAEIIHKSPHPELHIPNKTIWDIFTEQLDDHKHRDALICGLSHEKVTFQELHDDAQRVAVALAQDGVKRGDVVLMHSFNCMEYPLVVLALTSLGAVCSTASPMFNAQELAAQAQLANAKFIITNRALEKVAIEAAELSGIDKSNIYTVGASAEPKKLKCINEVSKRDFESFSFEKIDPEANLLLPFSSGTTGTPKGVALSARNMVANTLQVTHIEDFEGRMVSVLPFFHIYAMLLMHVGLYQGASQVVLPRFEPESFLDALSRYKIKKANIAPPIAIFLAHHPLVEQYDLSATKFLVSGGAPMGKEVETLVKKRLNVAVKQAYGMTEASPAVNYTEDDLRKPGSVGRIVPNTELRVKCTLTDKDLQPNQHGELLYRGPQVMIGYLNNEEANKKTLTEDRFLRTGDIGYIDNDGFVHIVDRVKELIKYKGHQVAPAELEDILNHHPGISDACAVRGYDADGQEIPKAYVVLKDPSSGLTPEAVMEFVAERVAPYKKVREVEFIDAVPKSPTGKILRRQLQDVENKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDP4</accession>
    <name>A0A8K1FDP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDP4"/>
    <dbReference type="OrthoDB" id="162896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441681" description="Protein kinase domain-containing protein" evidence="5">
        <location>
            <begin position="29"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="448"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="747" mass="82806" checksum="2FFF083A16530234" modified="2022-08-03" version="1">MMRVARRIRELLALIPVLYLCLVRLTMAQDASCATYGLTAAPDTPVLMKDPSDATSAVVVGTNCVAMKKTSITVTDDGDRSLRLSSLGIGKLLSYPPVEYLYLDDNKIEGFDFHNDTKLFHIQLKNNRLSSLESFQFPPRLAELDLQANTISNVESDILPDALKTLILSENNLTSLDNIELPTSLQELDLSKNKFRTLRTVEFPAMLTKLILSGNPLTGTEKAVLPSTLQTVNLQNCGLEFVRGLKFPSQLEHLLLDGNDIKLIEIRDSDVSVLKNLLYNLPAIDDIECEQGTKMVVKETTAVCVLSDDAFEELYGATSRSSAKADDTDATSSNVKPASMGSGDGNQSILLIALIVGCVILVGVIVFGIRTFWRKGRGNANDYASSNSLRMLSNPDSRSYKDTPNNFIVCTSSGPSLEMITPAGGDRSIDDVHYDEELVKLRIPSQHIEKKRVLARGGFGLVFLAKYNGKHVAVKQLQRDQLRQPIFDNFLMEIRLCATLNHPRIVQFLGVSWNTMQDLAVILEYMPRGDLFSFLRQTRKSSEGRTKDNKKKGVELVWFPMSDSKRGVTVSKAKLAAQVAEALIFLHGQETPVLHRDIKSKNVLLTEDYEIKVTDFGISRMQTLEETMTREVGTVSWIAPEVIKGGRYTEKADIYSFGVLLTELDTCYPPYTVGFGPNASKRTNTWIASMVSAGALQPALSSDCPMRIRELALKCMSFVPECRPSAVEINSQLKLMMKRSNSGEDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDT8</accession>
    <name>A0A8K1FDT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDT8"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001102">
        <property type="entry name" value="Transcription factor IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002088">
        <property type="entry name" value="Zinc finger protein ZIC 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002155">
        <property type="entry name" value="Zinc finger protein ZIC 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="28034" checksum="006B2D3D1623D65E" modified="2022-08-03" version="1">MNMETTYHLAAFDAPMDGVVDMMPPHQQPPPTVYTPTYHASEQLLHQDEGTTSSASSPAGGEDSNKEKWQKRHVCDVPDCGKGFDSKWALIRHIRVHTGEKPFPCTFPDCDKSFAEKSAMTRHLQTHSRDKPYKCTYPGCTKSFKGKDYLEFHLKIHAEGNPYACEHPSCSKTFCSPKSLKKHIRLWHNPGGKSTSMEQQLRERIIKMATRNKEKTRKFEATIRNLMDENEALKRRVAELEARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE77</accession>
    <name>A0A8K1FE77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_006352</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="973"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1017"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1053"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1086"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1124"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1186"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="195"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="562"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="784"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="976"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW56342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1388" mass="155027" checksum="D57169D185BE31EF" modified="2022-08-03" version="1">MGEDDGARVASLLAAMVDNDSAAFVTAFDACMANAVHPNGQSWLHLLAKTEMLDALDVALKYCDQSVEDVFERTPLMVAAARGNTDVCVKMLATGLVQDEDIANSLRVALRHNKSATCRAFVTQVPNEVMQVLLAAINRDDALEIQRLLEAGLNPDAGCTTGKRVQFAVHEAATRPAVLRELISHTVDVNMKDSAGRTPLSLAAAAGHAMACSILLDAGASWIIKDHQGRSPMYHACEHERDVIIKTFLKLGDSVNTTDSLHQTPLLYHAERGNMSGCLLLLRYNADVRHQNASGWTAMHLAAAHGHKSVCRALLSELTVDLAEANSVNEDTLCRPVLGLTGWTAVTVDALLRIYGELITIGAKATRLKYGTLMIRDYAMNTLLHLAAIHATDTQCAYLIRCILAIEAIPANIQNCYCKTALDTVRDRQMRFSVNLLLNLEEQQMSRGSSSFRVQLGSTLSRSVAVATPSSVIAEFTECSRARLLQLCRGIENDVYSCGTDEIVCQTDCEHGDSVLHFFIRDYCRRGSFPSVEIQRAVLLSASWLGTDSRMLRAFINKRNWEGKTPLHLAAEVGALGFHQALLEKGAAVGEECSGPNKRLLDQPSQNIQFWKPVNFAVAGDSSWSILPDTESQSQRIQLIELLLRQPDALPTDESALRHCQDTIHQRFPHLLPKFLQLKEDFYQKEDMATAKELYLRFLDECYGAYPIATTLDPSGVTLHKLFLDTESIGIHVLDKYVVNQCIIESTGDTLLHLVVAHGHSAALSLLRYLITEGSMDINRANKQLQTPLHIACDRRNAEICLFLLSNGADVTASCQNLKEPTVNPWFTPLYSALWSAEPSYEIIELLLSTPKSIIDPRNPRLGRSDAYTSANRSAKDVRWNDVVLKRLTEVHPSALPLFLDHFNVEVNRLSGGILFQFMEVRQACENLQLVLSPSAMASSKYSPSSCVTHPVIRNAIHLKWKLFGSRSHRRQLALYSLMLVLFYLSNVILPKLEVADPGVAKTSRFKWRDFESTVDYVVAVCKAACWWLALYHLVYVELFLEWRSDKGRYWRSLWNLLDIVTYLMMLVTIPLEVLNGWDTLRECLLSILSILLCVNLMQALLVSSFFSVLIFTFARMCRVVAQFIFHYLLLLVGFTGGFHLLFHGKGPHMNFMSSMRVVFLATFGELNYEQNFLSPDNEPARNACAFLLLVLYVIVVMIVALNLMTALMTSEYENVRSQAEERALLELAGALHRYEQWLGADVIKALYDSPRGEALLAASKRRIPMEQVRRRFGSRHASVDSFDVHPLTTRWKRALRQPAFTSMIHDKHIVPLRSNGVDGDVSSELSRRWSEEVGVLRREVASKLEEMKEAITAVSTRVNANGTSDVLAAKLDAVLERLDSSHWAKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEM5</accession>
    <name>A0A8K1FEM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEM5"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="64"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="339" mass="37337" checksum="7A437FB9410ECDAA" modified="2022-08-03" version="1">MRETPGSPVAATKGFRLQRHVDALYTLSKHFPADSKKTAQISTGISVEYAIHTKEMPGATKDEHVVMIMGFSGPKEAWAQTVDQLLQHWPAAGRNKNLRILTLDNRGAGQSTAYWGRYTTSQMAEDVVALLDHLGWKNAHIVGVSMGGMISLELAANFPKRVKSLSLLVTTRGNYVNDKGNGNIIRMLLSRDADTMAELVVGILYPEAFTAQKMADSNETIYTKLFTYHRDQINNAPPSSLSSRISSLSGWVGQGLAVKTHYVSDERLAAIGQAGFPVLIIGCREDNLIPGRESEILAAHIKGSHVKHILYEDAGHGFYVQYMDEFTQELISTFMRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFR4</accession>
    <name>A0A8K1FFR4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009443</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFR4"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="122"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="8"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="132"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="27428" checksum="CAA423A4ADFE9B17" modified="2022-08-03" version="1">MTGFDGYLADFESAREEAQQAIDKYEHCGDARGQEELLVEARSSVDEVERYIRILENEANEGKKSASDKRKLGDKVRHCKTQHQSLRSHLEKAILVADSRAKTAESAVATDVDGKQGAVRYAERLDRNGRHLDEAQRTLAETEAIAANVANNLLQQRNQLERAHMDVDQTQQDTEQAGSHLRRLTRKALTNKICLIFVMLCLAVAIALVSYYKWYPRNKKDYLGILPNATTVAPAPVPAPAPASASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGC8</accession>
    <name>A0A8K1FGC8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGC8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="301" mass="35571" checksum="260B832DBB60A982" modified="2022-08-03" version="1">MTEPTRMPLKNVSRKRMKAKMHYLRVLAVQLEKERDRLVGQVCHQYIESPREVAEDEYNKRLEAEELNAQLHDKLKEQTAIVERLKEVISRLACRVEDVHDFCQLQLDPDLFNRLLDDIHEGYRMTDGIVDTVDWDDEATRDVNSWNYSTRYYLTSQLEIDELVSQEKALFVRYRRPSVYRGKAINMFFTHLTKRFVETSREVRTWRCQIVGKSDGDESFMRVDVVGWLVIQPVEKDIVTRVCAHFVPKALETRRSDLTREENQDHVQENAHYAARMFQLNITRAIVETHSIESAPKVMHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHB0</accession>
    <name>A0A8K1FHB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHB0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="290" mass="32836" checksum="2B2FC1F2A249BDA1" modified="2022-08-03" version="1">MKTSRFSFRSPKMRVTGSNRGLTSLFALKARKSSLEDIASDPRDEHKAKTRTDHDEEEEEDDERRRIQIHRRRASSAPLPPTKTVEDEDEDEEEEEEEPHTSEEDDDEDVRATHPMPSDVLALQEELRLLERAKADAEHAWRQENTRLRTLLAAAKDREAKQQSHVEQLEDQLEAYSLELTRQQLDKPSGARSSTASCSTSSSPSANERVLLRLLVQIVGKEPLRALLAQTSPSTTPAQLRRRLITQTQTLRRRQPPASDASISPPSTSSASPPRLPRPSTKQYEMSDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHU5</accession>
    <name>A0A8K1FHU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">PIPK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_000164</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor Fz/Smo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHU5"/>
    <dbReference type="OrthoDB" id="70770at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00139">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="11">
        <location>
            <begin position="180"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="12">
        <location>
            <begin position="719"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1138"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW60122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1190" mass="133378" checksum="318ACDB462783711" modified="2022-08-03" version="1">MDLHIFRRNPEVLCSTGSTRSSSPRLRVPADEAPEPETVISPRPFHGLVTPSPSAFSIFSRIHSPYQPDDQIVEVDEASGYGTHGRRYSSNMGSPITSPTSVPRHSTTKQFRDPRRRSSLQITTSLRATEKRREPLWFALGFGWRPHRSLLRRIYFWFGAIGLFLFCFALIFVLPQELQRLAPNVIGSLLSFISSLTILVSYLFQPQNRRYPNELLVYVAICEFGLALLALVHVMVFCADSTTCEPMGFQSCSIMTALEMFLLIASVGWFGCAILHLFVSVSNPFANYKSQLKRYHLLVWGGSTILTLIIPLVMFSSSIQTRYEMSGAEICRAVGLSFPMLPSFTTDDERNRRISQWQVLNLGYWGSLFTLVVTMVIAAQFILAVGWWRSNSGTVIALRARRRMMKRMTTYVHTLNATWLVILVVFFTYRSNESTLDHLAAVSSASSASWNAAHAETSDVQIDLLDAIFHFVLAAKGYFTCVVWVAVNRHCCAFGPTLRGDVQRGSESGNCSSDEEEDEEEGNQPASRLTLISASAASQVRGPPRSLGITPRLPLTSPRFPGTPTPLHSLVSSSASQNNETLQREIIYYTVCGITKSILRSAQNPDTDVFFQQLMVGADRESAAQNESFISRAQSMGEYMSSPRAYCFASSHSSSFSTSVGPSVSFSAAQGARDDASERLDDSISSLASSSHSYANSTVSIPTPSTSVSNQHRSTFQRYSMYPVSHVPFELFEEEIELQSHGSPEEPLSLSPIFANLRRTATALYNHPKGRGIENPRPKMFIDYAPTEFRAIRKAFGISDENYLASFRSTAKERVSAGSSGAFMFFSGDNALIVKSMKERECRKLAKMIPAYADYITCNPKSRIIRFFGCHRIRLYGRNFYFVVTSNVLHSNGHTATITEKYDVKGSWIDRQAKLPQPGDLVTCSQCNATYEYGREDASTSFPFHVHRPDTILKDMDMKRPLHMNKGMARELYDQLVMDSEFLNAMGIMDYSLLIGVHKCSLQEAPWQREFRTSMSFLANSGEFHDSSSGQSTPKCGCHLEPIPEDDEHPEEMYFVGIIDILQEWNWEKQLEQVGKMLIGKSSSGISAVAPDTYCERFKSRMAQILQITEQDSTYNRLRKQVSAPPILSRYPENMEFHVVVEESVEDSEEERDVLEEAESSEEDELDAVLEFDAEVQAVSFDLDAGPPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI12</accession>
    <name>A0A8K1FI12_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI12"/>
    <dbReference type="OrthoDB" id="127950at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="54937" checksum="EBFE661A79FA7158" modified="2022-08-03" version="1">MASNKVEIMCAEYDEGDVFVLKIEGIAQVQELREAVYDSQRYKERYLFDTSELTLYMARAKNGEWLKDDRELGNLLRRGVSADYDKMQPEWTLEECFGKDFTSGRDDVQGADDSPCLQSTLNASTPTTALQLANVWESYEVSDIFRPDSPVVACDELMVMMKSFLYMCNAPPPDSRTKHSWVKYYEALLRIPLAMCRAKSIYFHERRHDASKRPDWVLLYKTLVLMRAEERSEGSHLHGTMIDLVTKMSRWNLVFYENLPYILAYVTAGDDIQVVAIERSSGPCRATPIVHLNLFQRGGEALKVFYNMSMLLYLMAKTVKRDHPCGLYPYVPDIKEHRTLVLLDGVIERTITRTQCDSNKDFERLVQIYTTLEELMRSGSDATHLLTVGELTVKDWTMVVELSPVGSRERPEVDQLCLWLQHLLTALKHWHALGYCHGDVSWRNVVFVPQDSFGYWVLIDMDQSHAQHEGDRLASHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI57</accession>
    <name>A0A8K1FI57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI57"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045335">
        <property type="term" value="C:phagocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090385">
        <property type="term" value="P:phagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00173">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF39">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SH2" evidence="6">
        <location>
            <begin position="502"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="608"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="401"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="611"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="746" mass="84318" checksum="8FBDC28CE010631D" modified="2022-08-03" version="1">MHTTKGSSTPSTPRHGANAASNATGGVPSTHNASPQVNVATEAATSSWMKMISSTLLGDPTSLFTRKPTTPRTAAFNAAKKGRSKYDVDDTRTFKIALVGGSGVGKTSIVRRWFQRSFQSTYSPTIGVDVFTLPFTYHGEEILLEIWDVSSMEVDNTQSSLHALLCEDLDGIFFVFNVHRVSSIAAIDKWRYNLAKYISAKELPFFLLAHKADMIQKRIMSSDDIAAYSKAGGYRGWIWTVGRPNFGENDKHPPVMQALDRMVECIWHERERKPQPVQTKGLFDSETQRRPLPVVHVDQDLHDFSTSLLRLPMKAITTLPRDENLLPIDEKFETPPSRQSFSNKPAAPGFASTWILGNEKAAFLRVTEDSVLAVHEDETDDESHDGWRQREEFAKGGKMDESEEESEEEEEDSDEEEESEEEEEEEGEEGENDDKEENEDDDEDEDEEEDAKSTSTVAEQEQAAEEQESHPPAMARRPSVHGLSEEVRRAQQLQNDLDAWRFFAGSISRYRAEEILSGREEGTFLLRRKDAQTLVLSYVGPDHVHHALIEYSNRRYFVGSSKSAQASFSTLYRCLRSVRRYAYRGLIFTRNVDFRVVNKEEMALEEDGVKPTQTLQVNTHHATSAWRSGSANSTPNRRGASPKKRNTRLSSGLLAHQEHVQVPPKSRIDEIGKTFYDQITQRLQLSSSQEHDSTSPISVAGLLEMVEEEKAELKGMRATDTEAQWRQLVKNMEVWNRIIVNLELQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIX4</accession>
    <name>A0A8K1FIX4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIX4"/>
    <dbReference type="OrthoDB" id="100955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008983">
        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="TNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="654" mass="69486" checksum="B9910F4067166A91" modified="2022-08-03" version="1">MTTKPSAPSSAPSAGPPDTASKPTPPPQIDAGNDGDKASTTATKPETTAAQPKASASTQLSGMGFANYQFHGFKTAPYAPMPPATDKMPPPPPVGGKKPETKAATATAAAKTETATGSGFGVSFAKAAASGTESKPAKSGFSFGLPLTTNVVAPETNSSSSFSFGAQPAKTTTTEAAKGFSFGTQAPTLCQLESAALKAFPPGTEIPKGFSFSPPEPPKPTQSGVFGTSNPPGATSGYRFGCFPTPPAAPAPTFGGDRGAGFPQDAPRPSLFGRAYFAPTSAAPAAVPVSSLFGGATSGTPAPSLFAQPVTQSGASGFVFPTQPVSAATPTATPVTAGSPDSTLYMMCYREPNVVFFPSRKNAQYRYELTVEDGKTVQFWLEDRETKHQWESDKLKLKDFVNEKNTIPQASIEDYASCFETCLNSVIVAPVDPIRDLLPHDTDDWELQLCVVNQVFRTTWTLQYSFILKKVDLDPMTLLQSRLRDQEAKIQALESKLQSLSTSNTSSQGFGFRSISTQPIVPKLTFVRALTRHHTVTGRALVWERDSMTTWGSFLSEPEHIQFLSNGNIRILQSGVYVINLVVQNQNSNNGLAFELQQNQRVVASCTDSNPSGHRNASPLNHVLHLVMGDELLVIYKGTNIAESGSSLVMHQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ67</accession>
    <name>A0A8K1FJ67_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ67"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="446" mass="49802" checksum="D1D500F40AA32BD5" modified="2022-08-03" version="1">MDSKPMDHAKRIHEDETRRADFEAARKRFAVYGKQNAHVSHYDSTSPTKAIDEKKKLKKQRDAVVMRSPQTKARARGMRMETDVSTVALKNSMLLQENGELATHLDDIEYHLDGILQHVSPSGVDADRLNTMTQSVIALTKLIRLEHVQAVLKVSKRGQAEQSVLDRIRDVVFLLTSIDDELLRLAVAVFAYFLTMSPDVDEVFTPEVIDCVVQCLSREAKRTGDHTAILQANHSSTPAHSEAPAPTQKSCLKRKKCGSVADQSSDVSSPNTKASGRATHTRQELASLLKAEEVFMVDNRPQLALVDILGMVLHNTLQIGGAQSSDQLATKSQPSKIRVQHAQEWAFRQHQLGVPKSNQEIGFRDETVFNWLGIADAFMRRVHVRLMVTVIVASSSSVHSDRGLVLVLLQNLMEDTLHKGYIPFQSLLRCSPVHLRVQHHGKVQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKA7</accession>
    <name>A0A8K1FKA7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKA7"/>
    <dbReference type="OrthoDB" id="10692358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035439982" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1192" mass="114348" checksum="351AE59C38856424" modified="2022-08-03" version="1">MKVFQTVVVAALAASVVSGITFDEADGGAYQNGDVGQRPPTPAPTPVVTTAKPTPKPTPKPTPKPTPAPTTEKPTPKPTPKPTTEKPTPKPTPKPTTEKPTPKPTPKPTPAPSSGKPTPSPSKPTGGDGETPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPSPSKPTGGDGETPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPSPSKPTGGDGETPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPSPSKPTGGDGETPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPSPSKPTGGDGETPAPSSGKPTPAPSSGKPTPSPSKPTGGDQTPAPSKPTGGDDKPTPAPSNGKPTPAPSNGKPTPSPSKPTGGDQTPAPSKPTGGNGDKPTPAPSTPSTGKPTPAPSKPTTPGDDDSDDTPCPSLPQKTPAPGDDDSDDTPCPSLPQKSDKPTPAPSKPTGGDQTPAPSKPTGGNGDKPTPAPSTPSTGKPTPAPSKPTGGNGDKPTPAPSTPSTGKPTPAPSKPTGGNDDKPTPAPSKPTGGDQTPAPSKPTGGNGDKPTPAPSTPSTGKPTPAPSKPTTPGDDDSDDTPCPSLPQKTPAPGDDDSDDTPCPSLPQKTPAPGDDDSDDTPCPSLPQKSDKPTPAPSKPTGGNGGKPTPAPSKPTTPGDDDSDDTPCPSLPQKTPAPSKPTGGNGDKPTPAPSNGKPTPAPSNGKPTPAPSKPTGGDQTPAPSTGKPTPAPSKPTGGDQTPAPSTGKPTPAPSSGKPTPAPSKPTGGDGETPAPSSGKPTPAPSSGKPTPAPSSGKPTPAPSKPTGGDQTPAPSSGKPTPAPSSGKPTPSPSKPTGGDQTPAPSSGKPTPSPSKPTGGDQTPAPSSVKPTPAPSKPTGGDQTPAPTTGKPGKPTPAPSSGKPTPAPSSAKPTREPTPAPTKPEEDYKQRSFFSNWDESYNAGRVGGEDNVDGQYRYLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKC4</accession>
    <name>A0A8K1FKC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKC4"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487127" description="5'-nucleotidase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="56"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="5">
        <location>
            <begin position="314"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57483" checksum="E58597BE10DF9967" modified="2022-08-03" version="1">MKVFGFTTVLVALFAVSSAATPRKPNAVIDLLSYNDVYEMLQDDVNGFKLGGPSRVVPIAKEMRTKNPNSLVLFAGDTMSPSLWSLQFKGMQMVDAHNAIGADFACLGNHEFDFGIDAFFNVSKASNFPWLNANCYENATSSLLRGTQPNAVKTLTHPEHGNLTVGLFGVMYDMKLPGGKLYWTDPIVAAKEQVKILKDEKKVDFVIALTHQVLDDDNRFSKEVKGVDLIVAGHDHSAMLQTNFGTPYIKADLDFRTIWRSQVEWFAANGSTAAFSRMNHKLVAITEELPTDSEFDKVLANYSTVVNELQKRVVGKLCEDLDLRQTTVRASDCAIGNIFADASINNYGENYADVALINGGLIRSDKIYPAGEFTLGDLIAWSPFGNTLVVIETNGASLKKFLVAQMLPSCQGFLAQQGSYMQPAGIKYVLKCTGIQQAELQSIEWFKHPTKTGPVLDDDVLKLTITNYFYNTNWAAVPGLTVSNVVVSEAESVRIDAALEKYVKAQPDSTLCQKAEGRSSVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLG3</accession>
    <name>A0A8K1FLG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maltase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005271</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLG3"/>
    <dbReference type="OrthoDB" id="96599at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03423">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035435398" description="Maltase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="8">
        <location>
            <begin position="46"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="9">
        <location>
            <begin position="186"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="7">
        <location>
            <begin position="391"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="670" mass="74677" checksum="D1C4F4FDAE83F31C" modified="2022-08-03" version="1">MVASGVGRVTQLLVAVGCFAAAQAQELIKKDDGSGVLTMLFQQPLWATPNIHFNDFKGNGWTAVPGFAMNKSSYSDDFAAANGWWQYNFENTSQLEFVFNDNNGTWDNNESRNYVAYSAGVWAVVSNIEPAKPPPPAFINGTGYTVTSVEETGNHITLQLLANPTTEPEQFGADVKELVVDITKKEDSVRVKITDKNTKRWEVPLDLYSKGDLSKDSGNGGQGQQGQQGQQGNAKSNLDVMYTKNPFTVKVTRKSDGYVLFDSSKLDLVFKDQYLQIATAVPTDLSVYGLGESTRGSMRLYPGDRHTMWARDQASSGEKINTYGSHPFFLGLNGKGKAHGVFLLNSNGMDVALEDGRLIYQVIGGILDFHVISGPKPVDVVNQYTSLIGRPKLMPYWSYGFHQCRWGYKNVSMLRDVVDKYAANQIPLDVIWSDIDYMSKYYDFTLDPVNFPQEEMAKFLSDVHGKGLHYVPIIDPGIPDEPTDIAYSRGLELDVFIKDTKGIPYLGQVWPGPTVYPDFFHPNSTTYWSEQFDRMHKMLEYDGIWIDMNELSNFCPGTSCKRYEGRQCPDGSSCCLQCTDDKNKWNYPPFAINNGNSYDKLLNKGISASSLQYGGIRQYDAHNLYGFTESIATNAIVEKIRQKRAFVLSRSTFPGSGAHVAHWTGDNAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM5</accession>
    <name>A0A8K1FLM5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="78" mass="8878" checksum="870CEA7F21B9A938" modified="2022-08-03" version="1">MARETQFRGSVKGSDVQQTVHPIRHCYPSIPRPSIDIQVSNGSPQPSNNTSTPQERGIQSSWKFVKRNLVKIHKTHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLN1</accession>
    <name>A0A8K1FLN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW64007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLN1"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="25170" checksum="8CE7094F063DCC2F" modified="2022-08-03" version="1">MIPRNLWHMASGLVRRKITKPEPGALYLYPSVWRSRAGLKDCNFGDKLTENAFLRHMELSVWYACGSMGLLHACARNRWYFVFGSQGVRVFKDIKAFQAYEVHSRVIYWDDDWQFLLAQFKCPETGELYAEGMSRVMLRQGRERVNPRLLHEDIGLPNLVDKEEVPELVQKFLAWDAVADKSMKRTADMNAIRYANRKGPAVLSAYSMNLPFAMKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMP0</accession>
    <name>A0A8K1FMP0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMP0"/>
    <dbReference type="OrthoDB" id="104149at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="44455" checksum="92205D767F614DC6" modified="2022-08-03" version="1">MEVELRVTRAHVWLSSALVGRQETFLALLRVDSEPPQLYHGSLEDSVEVPRGRKRWQTVPIRWLDPTRQSKAAQGSTLKLDETLPSVDVAVFAVLRPHETQADKEQIHLVAETTWSPSEKDVNAIRGSQEVVIASTLKQQRGTVEVCLRQRREETKDAVELTSDEARGSFSMHWTPSDALEQDLQAKERERVAHEKKLVRRLESTLSKARRLEVMRDEALVMLQRRRAAQSIQREYRRVLDKRRELRDAEKKVLEAQQRAKKLAVRAKVVERSERRTREMLDQLKRRHQPPRLRDERVEGPIIQTRDLTQWRRLEEAKTYHKLYEKLQRLEDERQQKLAELAISESIPEIRQVRTRYEPGRDLDDALIRAIHHVHLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMT5</accession>
    <name>A0A8K1FMT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMT5"/>
    <dbReference type="OrthoDB" id="46760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24134:SF9">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24134">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="181"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34135" checksum="20E3692901D38677" modified="2022-08-03" version="1">MVKMLLDYGANPNAVNQNGETALFIAAANGHVEITSSLIARGADPTITDMIGGTALHSACYAGKMSTVRSLLIRDLDVNVQNKEGYTPLHLAAARHTDVAELLLAYGANAKAKNQCGSTPLHEAIRCSKIPCMNLLANHVDLDEGDEDGATALFIAAKAGRRDAAKWLLEHGVDVNKANKKGSTPLHEACKNASLELVTLLLAHNAGVNVANEVRDSPLAVSLQWDAEKSSCVPILKTVYVLMSHGARVDHSEENYPVVTNSKVQGSASVILMCVQHWAEEQKSKRPLTKVEEHILVRGPQDVEAFLQAKNILVGDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN02</accession>
    <name>A0A8K1FN02_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L18a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN02"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="6">
        <location>
            <begin position="4"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="20591" checksum="1AD8D2831E19939B" modified="2022-08-03" version="1">MPIRQFQVVGRKAPTDKEPNPPAYRMKIFAANEVLAKSRFWYFLHQMKKMKKTTGEILDINEITEKNNRVVNNYGIWIRYNSRSGTHNMYKEYRDVTLCSAVEQLYAELAGRHRARPRSIQIMRTAIVAAKDTKKGNVQQFHDANIKFPLSHRIPRPSIKNHRTVFKASRPCTFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNK5</accession>
    <name>A0A8K1FNK5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GlcNac transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNK5"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035468050" description="GlcNac transferase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="59798" checksum="46258BE853730B32" modified="2022-08-03" version="1">MVRLAALLTALLAHGAVVSADSDAPPTLHVANGKGKVELDPTVQHIPLKPELKNLRPPPARVPSTFDIYVGMSVFRDGVRCGKTLLTGFKRATKPDNLYFGIVDQVYDGDATCIEEYCKLASVEWPEHGECRYREHIRLDKRNAHDSRGCAPARHYQQKLLRDEEFCLQIDGHSIFTNNWDENLVADWKQTDNEMAVLTTWLHDIHDFVDEDGNNNVPDFLPHLCATFRGGNGLVRTEDASMISGSTVPQLGTLLGGGFVFSKCHAERRVIVDKHAVWMSDGEEFLRGSHLWTYGYDLYSPSPLGSVVYHNYSRVPVRFETVKIDKEQRELEIEMGINRFHMIVGKDFEGYVDAKEMDKYAYGTVRSFQTYLNFSGVTFEDGKKDQPRYEQLHWVPYENPEEIEKLVGGGWKMYPTPKVTERPRSTQREVKEPKIVVLGKRPEHDDEAQLRDKLAGHGAVGGEPKEANLRQELADLVRLDAAKTDGSIDIGNVLYLLFFAGLLLMVAFSYKDLRRQCRRKSYDRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNW6</accession>
    <name>A0A8K1FNW6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNW6"/>
    <dbReference type="OrthoDB" id="73372at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36252" checksum="485A893DA110AE13" modified="2022-08-03" version="1">MTLKCWTSAIREPQPTDDVTEMQYSASSGSSGTVGSATIPAPSGPSTISIVTTSARPHPTSQSFTEFRRRSVGFIHTTPLVPDDGLQGLAMTPTRNYHKANRYRSLSSNWDKMDSDEDSEVSEHEEKHGENGSTDQRRRDLMFTPMTSIGRHFSNNQTAHHDFHTRRRAHGPKSARNRRRRTMSESSGSASRRVRILSPASSKVFFCGWVRGQSAEVRWEVVDKSVQSVRIDVCNVAWAVPTTIAHRVPNDGYFQWKRVYWGMPITDGYYVNIYDVTDLPPEEQQTESSAPQPNQQENQDKDKTEKIELALLARSECFAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNY2</accession>
    <name>A0A8K1FNY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Poli38472_004112</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15614">
        <property type="entry name" value="PHD_HAC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038547">
        <property type="entry name" value="RING_CBP-p300_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47040">
        <property type="entry name" value="Kix domain of CBP (creb binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 17" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="20" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="23">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="24">
        <location>
            <begin position="695"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="22">
        <location>
            <begin position="1289"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="26">
        <location>
            <begin position="1555"/>
            <end position="2041"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="25">
        <location>
            <begin position="2043"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="24">
        <location>
            <begin position="2111"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="523"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="809"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1028"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1091"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1155"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1503"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1804"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="2086"/>
            <end position="2116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="2220"/>
            <end position="2244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="20">
        <location>
            <begin position="919"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="20">
        <location>
            <begin position="1361"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="812"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="834"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="893"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="21">
        <location>
            <begin position="1028"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1062"/>
            <end position="1077"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1091"/>
            <end position="1109"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1163"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1513"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="1806"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="1824"/>
            <end position="1838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="1857"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="21">
        <location>
            <begin position="2094"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="2221"/>
            <end position="2233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="TMW66347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2244" mass="248423" checksum="BB032BCCFA174E50" modified="2022-08-03" version="1">MEARYDAFKDPKIQGDPYATLFVGRLAYTTSEATLERFFSSYGHIKHLRLVRDVVTQQSKGYAFVEFKSERSCLRAYQDAHRQELDGRVLLVDYERSRIAMDSQSFVGDFNLGLPGDNRYMNGLNLGGGMTGIGGTNDLMNPTGLDFSMMMMDSSIGASGSSTGMIDFPDELNSPRNSNNANPTGMSTGMAVSSAGFTASSVAPTSAVNVSSTEAIPFPASLANENVSSLSMNNTAARQGGVSTSVPNLSSNTTFGDVELGGNNFGGVNMNPMGGVNMNLNGAVNMPMNPGMNGFMPDMNMNMNMMNWANTMQPQQPNGMMMMNMESQTYFQSPQQQQQYMRMLQQQRYFASMQQAALQQQQRNMQAQNGGVGVGLQPQQMTPQMQMAGQQMAGQQMTMPNGQHTQGTAPNQLQVPTTAVSSATQRPTVTPGVATTATTTAGAAANATRQPWHSPADQALRKEMLNHIMRVLQSQRANAPANWLQRLPEMARRLEEECYRISASREEYANTSTLQTRLKNIVRSAQQRGRTPTSAGVSSGLSTAQQNTAPAPAQMTAPAPAPMAIPFPGADAVAPTASPPINAQPMQMPPELQDPSPAPPPMKPDVSQAIAMPLELQDPVQPPNMSMMGAPQQMMDATAQKNAAAAIAATNQNRSAQILRQFKARAQQVTSALEEKQTREYHNKLQSMTTSESMTVNSKGVLQRQQQRLLLLRHAMWCKAPDGTCAATPNCGEMKRLWQHMGNCQETTACSYPHCISSKYVLSHFQQCENPKCLVCQLLRYPVEVKEKNGALMMDADRALQQIQVATERRLQQSNGQNPAQAPQGMSHPPSVAQPMMPNQPSQPSVSGPIQFPGNMMTQQPLAMPQQQQPQPGTTLGGTPGTTSMMNGTMQNPVSTSTQPATAPSASPTRPTGFVPGLSEEENRQLAQIQARLRGVSLEQLNLNCKKLEGYAEQVRSQVNAIMNEIRQLLQMSNSTQDPNLKSQYDAQVQAKRTMLQDLNQRYKKCSSQHRIVKHVISARINAAPLTGIPPPANVPPPAPTPAPVPVQTSQPMNMRPLEMPSNLQGPTPTPPVANNQQVPVTSFTAQLQQANEDLRRSQQQLIGQTRAQSPDDILGEDMPASVGGAGMGGAMPLEMPSDLRGDAPAPAPVPAPVPMSSPTPAPSALAITAPSAGTAPQPPAKNEPTVNPLTMNNSKLNAMMQEYKKLGTPRVKAEPAVTVNTSEVAAIQPVPSPPVVTAAPTDVPTSMLNELSNDDLKKHIDSLVKHYNATMPPATLKKRLEGMLKGMMEHKFGWVFSSPVDPVALSIPNYFKIVRRPMDLGTIKKKLDAGIYKHMDQFAEDVRLTFNNAKTYNSEDQDVYNLAKDMLNDFNAEMRKLEAEVHEEEAAARAKESSCRLCGVERMVFEPAVIYCNGECNSRIRRNCYYFTAPDNKYHCCQQCFNVLGDSVRTSEGKTFRKAELAKKKNDEVHEEPWVQCDKCNRWVHQICALFNGKIDAEKKPQVVKSENNKVSAPGAPGSSHSISSTPGSEFLCPECLLDHRIKEPEKYVVGKHAFSAKDLMRTKLSDFLERRIYKTLQEEREDEARWTNKTVKDVPTAEHLTVRVVSNIEKQLMVRDKMYQRYRESHKYTTEHRFKSKCICMFQEIHGVSVLLFGMYVHEFDEQEANCNARRVYISYLDSVNYFEPAHLRTKIYHELLIAYMEFVRQRGFHTAHLWACPPLKGDDYILYCHPEAQKTPKSDRLRQWYVDMLTVAQKEGVVKHITNLYDEYWRQDNTACVLPYFEGDYWVGLAEEVIEKLEAEKPKKSKKGTNKRKSSTEMKKPSKKSKAKKTKRRKTSSAGTGTDAEMENATGSDGEGEADEGDDGNESVDEAMPSVETKERVITSLDDVDRTVTDPLMIKMGEVIEPMKDDFLVVKLQPYCQLCNTPVLNGTLWKDPTTSTELGLNPKIVQTCLCDGCYQKAKATPNAKVQEQLKVLQPEPVTWPEKCADPDEINDSEYFDTRQAFLSLCQGNHYQFDELRRAKHSSMMALYHLGNPNPNAYVYECNACTRDIVSGNRWHCNTCPDFDVCDACYAKEKHEHPLEKIPTSGVGAPGGKGGQGGAHGALTEQERREREQRAKNVRLHMQLLVHASACDGSCGSANCDKMKELMRHGAQCKQRALGGCTVCRRVWALLQLHARQCRQYECKVPRCHDLRQHVRKLQLQQQLMDDRRRAAVTQQYRQMQNGQSGQQEGGDDDPAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNZ7</accession>
    <name>A0A8K1FNZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methionine aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004157</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with zinc, cobalt, manganese or divalent iron ions. Has high activity with zinc; zinc cofactor is transferred into the active site region by the ZNG1 zinc chaperone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Associates with the 60S ribosomal subunit of the 80S translational complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNZ7"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031615">
        <property type="entry name" value="Zfn-C6H2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15801">
        <property type="entry name" value="zf-C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52013">
        <property type="entry name" value="ZF_C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C6H2-type" evidence="11">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="41929" checksum="0C6AA5B100BF8989" modified="2022-08-03" version="1">MGGDACVTPTCNKSGTLVCPTCKKLGIPPAMSTFCSQDCFKGYWSTHKALHKMFTQMVAEEQTQSSASGFDGFEFTGKIRPGKISPQQTVPDHIPRPDYWQTGVPVSEQQSDNSIPVYTKEQIAGIREACKYGREVLDIAGRAIRVGATGDEIDRIVHDACIERGCYPSPLNYYNFPKSLCVSVNEVICHGIPDSREFEDGDIVNLDISVYKDGYHSDLNETFLLGNVDDEGVRLVKTAFECLQTAMNLVRPGTMYRELGKHISAVATAQNFSVVKTYCGHGVGSLFHCAPNIPHYAKNKAVGIMKPGHIFTIEPMINVGTWRDKTWPDDWTAVTMDGSRSAQFEHTILVTETGYEILTARENEPQMVWDISKVQRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPH3</accession>
    <name>A0A8K1FPH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription initiation factor TFIID subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005837</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPH3"/>
    <dbReference type="OrthoDB" id="341924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="23908" checksum="71544CEA00130DA6" modified="2022-08-03" version="1">MSTASGATKSGKSAAASKSNGSAGGAALKLKPGKGLQEDDGKDSETEMTDAVPLDVAVLQRILESMGADKHEPRVVNQLQEFVHRYVTDILIDAQEYSLYAEKQAVDADDVRLAIASRLNHHYANVPSRELMMELADKRNSVPLPPISNEYGVRLPPMQHQLVTFESERHHDGPTSPLSIQYDASADEDEPMTLASQREGARNKKIARQQIPIHISQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRC0</accession>
    <name>A0A8K1FRC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006305</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRC0"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rhodanese" evidence="11">
        <location>
            <begin position="154"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="869"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="971"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="1005"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122900" checksum="3860CBF46DADADC7" modified="2022-08-03" version="1">MVADPPLWVECGVWPLRVSAAPPEELNKVEMAAAVRVCVPQADAARVDARVQEMLAVVDAAVQRSTATDNGEEWVFTNASTAEKHADQRVWTLSTACFLYWTLADVQGLSVAISDANDATWTSLNAILNLETTGEEAPPRVRALDASEAAELIADGEIQIVDCRPQDDFYGMNDQSSVSGHLDNAISIPFVSVFQEDQSSFLTHEELVELLESAQVDFMKDLVVVGSCAVEAAAVATVAMLAGHKGASFSITTLTQSFVDGLPQSTRSGIFDAKEVLFVEEDGDFDLSPSAASPAKEDVETSKDVVKEYDEFLKNPVKDKTDDEDDDEPQAREEIVWVSEIGHRYFDMPHPVDKHLFVATSRDIYRVVSFVLAPFGFPSTLQERFTVSEVKARCSSLYQDVIEVCSDLVYHHRDLNEGAMAMSVHKWVEEKRDPLCSEQVRKINELVDTLYAPPRFVEVPDLSESRVMEITEELHTRLLEAARKRAAWAFDVAAENEEDEDVEETKDTGFSGWGQSFYPSVVYTLGFLPQEPSSNHKKLSTLQIKTFIQVVAEAAWGVIESESLTQVEFQALCDTLVADNREVIAKIKESAEKALYVVKHSLTQSMEREEDLEAQLLAVQRATDEGERAVRSGRHQVALATFANAFKHLPIFHKETAPLLVGRANTFIKIGELGRAREVVQVLLKLDPFSCGAYGCLGEIEEKQNQPDSAMQHYVTAFILDGSRSPERAADIDRVARLVGRNVARNIFKAMVLQHELPTQWLVESYFDSFEHDVDNALRIPIEVEKMANTDASELTGDQLVQRAFFLKRKKQYRASQADVRAALDRPIEDESLRAVALNLHASFLYVAGDVHAAVEAIAESLELQPESVNGLVKKGGFLSEIGDMEEAAECFNQAAEIDPNDADVYLHMGQKDLLEGNYYQAVQTLRRSISRSEALPVTHVSYGMALYKSGSVFQAIDVFEDAAKAFPNSPEVHLFYGEVLADQGDYASAMKHFLRGFELSPLCPLPFLNAGRVYVSTNDPMRAIAHFQQALEIDPRCSSAHLDIAQVLFAQGRTTEAFEHFDTAAHCCRFLPEVEEVCAAQEMAKMQERVTDILGVDLRHLMRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRE3</accession>
    <name>A0A8K1FRE3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7726 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRE3"/>
    <dbReference type="OrthoDB" id="2592504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056143">
        <property type="entry name" value="DUF7726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339:SF1">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24852">
        <property type="entry name" value="DUF7726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="88"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7726" evidence="2">
        <location>
            <begin position="200"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="33692" checksum="EAA49008487820D8" modified="2022-08-03" version="1">MSAATDATLAAMAPFAVGGLTVPVIPSAASAPAQPAPKKTTTKKTAAAKSSETRVTAEAAVNSINFDFTDDEEEDEEAQAVLFQELARKTNCDALRRKIQRFLAEKTMTQTAFLSKIGVNSNSFRRFMQYKGAYRGSDNGTYESGLFFFHKLEKKLGTARGKGKAKGAAAAKGPSRGEKNAQAQELFDKIHVVTLEEPVYVYDDCDDIRKKLNELIASKRVTQAALLRELDVNSNSLRRFLTTKGKRDGCSNGVYMAAYCFFEKLRIAENKPKSGKRVKNEKEMPTGYSLERDPTHFWVLAGERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRN4</accession>
    <name>A0A8K1FRN4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRN4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="84" mass="8838" checksum="717ACCA94860C0CA" modified="2022-08-03" version="1">MPRQIEAHGNEDETNEAGVWVIHSLILAFDAAASFPHTLTNSNLSRMPKGGKKGGDKGGETKQAEKKEAPPAADNKKGGKKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSB5</accession>
    <name>A0A8K1FSB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSB5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="48544" checksum="CD4E19C8F88E7576" modified="2022-08-03" version="1">MDEVEVELECAVYGEGSVFPVKIARDAKVSALQKAIFDDQRYHERFSFPPSALTLYLAKKNGAWLADDDNLDALLGGDVDKQYMKMRPSWILGEDYLGANFQPGRKEIHVLVELPEAAAGEKSVTAEMDKKLDKVLEHIMQPKRKRYVHSEMSSTKGNALLQDLNIRLKFVGTVPFTARYPAPVEGFKWESIDDGRGQNIAFTEEQQRERYRTYVEDNIGDVLAEKKLCVLGVEKGKNILTATVPGHDIDLVGRTDILVLSALAKQFPHYVKGLPEVKMLIEVKRNVKGGSMFQALSELIALDILVADPVMALLTNLTDRWQFFWVSEKNNNYVNIQTTTITEPGAAFAVIRTLLAQSPNGDADITLPYFEGPVKRRKLAQLLPSIGEGGESSGIREAIERYYDIASVLGPDIDMARSVAHQIVRTIPTFSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C233</accession>
    <name>A0A8K1C233_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C233"/>
    <dbReference type="OrthoDB" id="158256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="569"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="611"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="71397" checksum="CC9A000406010E60" modified="2022-08-03" version="1">MTDRGKKSWSFISEESFSGRSDNPLNLVDFETLDNNLDHDPDQMDLAADMLRFQERMQQQPTLPKPAVTTREPRSASTPNTRRKMTVTFKDDRDSIPVVVRRSSAPSPSIQLLEEPLYRTRQRSNTPQNFFNHALYSSLRTGDTVEPFSKDYLGLIFTGAASGFMVPFLAECFHPLLSVYLNFNGDQVHATERFLVLPGVISFFIGMLSDFYPLWHLHRKAYIVGGWVFAYLNLMALVVITMIDDGTDLRGNNVRTFYGGIVYVLLMMGTSLGVTIASVTTTAFLVELSQREAIHERGTVMMKYLITRRVAMVASAVVTVASMDFDEATGRTRSVISMKVMVLMMAFVSLVPIPAVLFWLTEEKREIKVDSVDRSSLSHQLWNILQQQAVWRIILFICATFFLVYFQFDNATLAVKFWANATPDAVREGEIPKEAIALAVLIFYRLYLLNYSWVRLNIVALVLFVVTSLVSGLPVVFNGARSPWYYVPVESMDGVFEGVLTIISTLPLIEIAETGIEGATTGLVASYDVLIRSVVATFSDAIGKSSTSLVHDFSPEMLQMDKSGTRWQVAGFILGNAAINLLAILPILYLLPHQKLDAQQMRTYGGYNQSAGIAIATLFVLLVIYAATMNILALVHKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C234</accession>
    <name>A0A8K1C234_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW55008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C234"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453523" description="Thaumatin-like protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19311" checksum="CCCC6F31E5E8BE77" modified="2022-08-03" version="1">MVQLIRSLLTLSALLLVTPASAVNVRFTNNCPKAIDLQHASGMFSSFKTIAKIPMGGARAQAINKGTHSFRFAGSALVRLLYTLLDRAAEFSVTATGVTYDISVDPSAGQCNTSECAIISKLGMDIAPKKASGASCRPVKCPKTDKAACAAAYDKEKQACATSTDIDVIFCSKGRRLRSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C249</accession>
    <name>A0A8K1C249_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Parafibromin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013802</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C249"/>
    <dbReference type="OrthoDB" id="2186602at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032041">
        <property type="entry name" value="Cdc73_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16050">
        <property type="entry name" value="CDC73_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Paf1 complex subunit Cdc73 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="7">
        <location>
            <begin position="257"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46975" checksum="F657F153B2523428" modified="2022-08-03" version="1">MAMPEDVAVLQALRAHVIKGRTLKVDGEDLVFVDVNDQELQRQPKHTATAYHAKSSKKPYDLLAVWTCYKYASLTFSDYVTKCRAEKAAMVSTVDKKELMAYLKGDIETSAQIHAEGEAPEAEDAEPATKSGDKRAAEDEKDGGAEAAKKRRVEAEHRREKENKPAKTTTSSASTEDKEADLELKKVLDKEYTHRNRTTVLLAAKKNFENVLKSVEASNAETKEKIEKASKEKIVAPVAARKEQQPLSKLVQDKIHGTPIIVVPAGFSDLLTMLNVKDFLCDGVYVSNMQKKSEGQRKSTSITIQHEENGEKYTFNIVDSVARFRDKDWRCVVAVIVSGQQWQFKGWKWKFPVETFKRVCGVHVYTQGSQLSDEIKQWDVKLLMIHPDKRHLDKVASREFWRYLFEFLKHKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2B8</accession>
    <name>A0A8K1C2B8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2B8"/>
    <dbReference type="OrthoDB" id="78299at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="39748" checksum="279FDF5D0BCCFA93" modified="2022-08-03" version="1">MSAKGELESLEFLQHFSELPTPGASTPSHLQAIAGEWTATASGNGPLDLTPTSGDGVMLLPMTTKRANWTRRLVVTKQPASEFYKDEGGKSNALEVEVTLVEFNEHGESARSPDEEFVDIPLRILLFFESGKRVDDTDQEIFRFVGNEYDSVVIRAATRKASVQFRLEKVSRRKDGQRFKLRIEVDQEQCTANVADLTPIFTNAICVLSKRKHHTQAADNAANRAKEPPIKILKRDLTKIEEKMDQHMNTVLEEMGRVHRQLQLQNELLAKVFMPSASSISPCHSHPGESSTMEWFLKSGVMEEILATKPLPLPLNTTGLSYLTVSDSDDRDTQSSPTSSDASVVEIPSLSAVSFAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2G8</accession>
    <name>A0A8K1C2G8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2G8"/>
    <dbReference type="OrthoDB" id="125270at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="311"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="499"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="564" mass="66970" checksum="2511023A0F0E835D" modified="2022-08-03" version="1">MTDGEAETVHLVPSHADEQQHDPNEEINQLRRYIMDMMHSEMEVIESIRQNEENVVTLDGRIEKFKEAIESEQYRNKNLCRLLREDQKDLQLLEDKKTVVELKHRQFQESVSAREAEVDSLRSRYACLRKHWQSLSVQRNDNERVIQELCKAEGHLNCRMREVKEKIQSLMNSISDHAELQKVRAKRRYIDEHSAHIKKDIGELDERRTKLVAESENLSSDIVRLRITIRAAEEEGERQLEVYREELRDTRAQIDRNRKKLIAKQKKFRIKCKSEHATLRRRITFVSTDLETNLMANEDILSSIFPLVEEHNQTEARQRDMETELKETEGQISDLIAQVQEIESCRGRFDTKDMQKKLSQKRQELKDMMHALRAKEDEVKQHEDNEKELKQEIARLDEVLSNQTTVELERALSAQRAKMKDLESEKHHLDELAKSLEEKNSLITTETERQQRRRKALKRELASLRKRQKQLASTCTELTTKLEIKKKLSTELASGIKLHETLQEEVYQMKQKNERERDLRTQALKEKEQCWKRECLEEETRLKAELQEWTEKVNSVKEQLAFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Y2</accession>
    <name>A0A8K1C2Y2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Y2"/>
    <dbReference type="OrthoDB" id="6344460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1470.10">
        <property type="entry name" value="Photosystem I PsaD, reaction center subunit II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053233">
        <property type="entry name" value="ABRA-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715:SF0">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="743"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="880"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="998"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1092"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1257" mass="141898" checksum="D58052955283D3E0" modified="2022-08-03" version="1">MDASTPEFQAALRDHAKSLGVDPDKEAALMSLVQEALLAELPDDWEQGETEDGTLYYFNSNTEESIWEHPLDGHYRDLIKAKKKELSETKETKPAVEEKLQPAKALAASNPIKTEASNVEVYSFDDVSDDDDVKPMSSKPATTASKTGSGGLSRIDSLFPQPAPSFSSATTVSSIKQDSKATSSIKATNSSRENTTSGTGFGRDRSWLLDDEDGDSTPTPFTKPTGASASTTSSTIESLRPSSALGSSSLTSRNAASTASSLTASYTSRLFGANTTSVPTSVSGSSSTSSVPAMTSSNLDLNALGSALSSQQNVVSKTSPTRASIASTIKGPFFQEMNSSAPTAATTTSITSAADLNKIKELEKANNELTKQVEQLQRDLTTTKQQLETAKQDAKEANYLKMKVNENKTKLTEKETEVQRLRDEHTTQLKAIQDQLQSVQRENDRLKSSQQQQATQSQQENIEVKKATTELRTELSAQQKQYEELQQSLLQSREALADCEKKYQEGVKTLDRTKEEHARELTLLADKSESARRQHESELRAIREQLESVQKEVADRDRQLESVEKELTDRDRKAASLTVLQDTIDHQAKSVKELEEKVKEAAIKLTDIEAKEANADRDLRLKEQEVSSANRQIERLTGDLENRGKELRELSDRLRTEQEQTKEAQSKTFSWKRQEEEWDRKVKLLEHERSGLEAQLRDRSDQVHAVQTQLKKAQEEHITANSKLHSESHELHVQLKTIKSQEVAPLEKQCDQYQHDNNRLQEKLMAIEKELRSTKSELATESSRNHQLQVEIEAWKRKEQQQKAQRDAYLQEKLSLEKQLTSLEQETSSFRHEKRLELEKLAFRQRELESLVAQKDYEIVRVEERFTKAEAWRLKESRRVEERELQLLELKEELAQLKSRNIDAENNVIIQELRREKEQIEHRVRQLTQELEEERVARQVSTQKFQDDVASMQKSLEWQIPQLAAACVNRSSEEWVRKCHQVVKTLRDDYNMKTLTERNELMTKIKEAQESRDHLEQKYKNTIAECEFLRKEVHRVEDNNKVLLDQLHTIRVYMTQRPLAAHGLNSTASMHASNQPPTPPAAPMAWSSPSQAPSPAPPPPVHAGMSFVSPSSAYSDFAAVNQLNTQLAVLHAQFQQLFDATERRPAVSTTSFSSHYSPSERFEIPSSPLAATKRPNSHEKPHDTSSSSLDTTLDSLLDQSQLSVSKKDLHKEQEQLLASLEAIGTPTAASFPPAPIVPVSSDSMWYQKNYWRAKYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C331</accession>
    <name>A0A8K1C331_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C331"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000006">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000002">
        <property type="entry name" value="cullin-3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="6">
        <location>
            <begin position="363"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="798" mass="92514" checksum="EC1B9107F01DE2A4" modified="2022-08-03" version="1">MGMDLTRAQEIWESLRKAIDEIFSHNASLLSFEELYRNSYNLVLHKHGDLLYNGVIGVITERLERIALDVSAVSDDLLLVVLNQKWTDHQIIMTMVRDILMYMDRTYVQQKRKHRIYDSGLYIFRDVIARNPNIRERLRHLLLRSIDQERQGELIDRSLLKNILRMLVDLGVQSNTVYEDDFECYFLERTLDFYRVEAQVLLDQSTCPEYLVIAEKRLLEEANRVTHYLNASSEYKLKNIVETQLIKNHAKTLVEMENSGCVAMFRDNKVDALRRMYSLFRRVPSTLHDMSECVLQYIKTTGEELVKVQSNPETAVDTAQFVEKLLSLRHTFVHFLSECFVDDPQFYKSIKQGFEGFMNVNTVCAGYLAQYLDELLRSKTRYEEELDTRVGDVIALFRYLQDKDVFEEFYKVLLSKRLLNGRGTSDEAEKIVISKLKAECGYQFTSKLEGMFKDISISKDLMELYRKFMHSANSVAVKSEFGGSADYSVDLSVAVTPLTVQVLTSGFWPTEVPQAVPDLPQELLHMTRSFEMFYVSRHNGRKLAWMPNMGNIDLRATFFGSVEEGKHRHELNVSTYQAIILMLFNQRPTWSFKDIAELTRIEKSDLKRHLISLCTPKFKILIKSSKGKRIEEEEDSFTVNDGYKSKLYRVRIPLVSQKESSLLPMVASNGMSNSAEDLPPTVAEDRKHLVEAAIVRIMKTRKQMQHNNLISEVTKQMSGRFTPTPQLIKLRIESLIEREYLQRSAMDRRVYNYLASVQRDIVALLASGITSLDLSCSKKLAETGQRREKSQLIQSRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C351</accession>
    <name>A0A8K1C351_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C351"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471426" evidence="4">
        <location>
            <begin position="28"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="550" mass="61344" checksum="03B7C560B98FBFE5" modified="2022-08-03" version="1">MQWKVSVWTVMMLSVLVLLMKTTIASAEAVADAFPLASAVQSELYIVLVSIPVLDKVLPLKNLAEELLHRGYRVGFALPENCWHWVSDLEHHEFISLGNIVGKGRATYSDHQELQTLGVYESYATTLRYYASFQRPMFNALVEDLEEDRPDLLVVDRYTFAGFDAAQRLDIPFVVNNPSLLTDIDSPPAYVGAPFSNISMHTPSAWERCLNSFYRLRFRLAMVQVFKEVNQNRRDQQLPPVESKEELYGGTLVLTNSMFGLDEPRPIAPQFQMIGMLQSPHHRPTPPLPIDFEYWLATNPLNKPVIFISFPSNIPLAPEFVTTLMDGLDNIGARVVWRITLQEQAAFDLRSRSRASVFFLGDDVDETLVLEQTPVSLLITAGDLHTMQQALVVGVPILGVSFSAEQWEAVNAIVRAGAGLHVMSKTFSETTVREATDQLLHKPSYSVAAFHLGELLKTGGGTQRAADHVVSVAQFGASHVLPARNLQPLYKTYLVDVYFIYGVILCGAAVILRTCFAVLYSIFQIAPDVHLGVTLDPPDEPVTEPREKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E9</accession>
    <name>A0A8K1C3E9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3E9"/>
    <dbReference type="OrthoDB" id="93876at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="1">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="170" mass="19230" checksum="5656A34CA4A77D48" modified="2022-08-03" version="1">MPYESFATEQVVKITEVVQDPTTNAWMYMVRVQRGGIRVCDEEEEDGFSHEYMISRRFSEFKQLHTELAPIMGDKLTPLPADGLMTLIMADNEELLNTRKEVLEQILLDILNHQDAKELPEVLEFLGFESLGAKIMPPLFNSGQCVGSIRNTSSPCWTTMNPSRSSIVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W8</accession>
    <name>A0A8K1C3W8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3W8"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="34950" checksum="FC090E386232FDDA" modified="2022-08-03" version="1">MERTVLLFCHAVSLNGTAWNPIIRRVASSPLLQRFPCEIVTFDYRYHGANHDFSDLGKISFLNGDKKAPRADHDLRLWTSWGAEELEIIVGRLRADDDKLSRKTRIIGIGHSLGASSLIKLEILRPGLLDGIIAFEPVCNCEFMPVDANALITMMVANTLRKQDKWNTWDEVLQHFSSAKHYSRWDKEAIAAFLESGVIQAPDGSYRLACPPSQEAAAYCHTMLRFTEEDHQRMRCKVFYEHGEHTKLFSPEITLDITKSVRDKVIVAPAVKDAGHLITVENPAACAERILADLREFPAFQSNRVTSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4N2</accession>
    <name>A0A8K1C4N2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4N2"/>
    <dbReference type="OrthoDB" id="58218at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="26881" checksum="E47A845A7571EB6E" modified="2022-08-03" version="1">MTSLADPKRRLKLLLVSDLDGQILRVTTLCEQIVCSHDSDVDAVLVCGGLVSESAPGAYRTGESKAAAEGDMMALISRLETIVCRVLYIPSSNDPPTTRLASPNLTQYSINCHSRTEQLTDGVGVMGENRYTKLLGDGKDPAENWELLLVLRDTSAVTALPAPTFAAVVLTLSMQPIDDASLFDYHHLELIGGPHQSTASKTPVIFPGSLRQGHFTTLELVKSDTDDSWSIHAVHLHDLEFEPEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Q7</accession>
    <name>A0A8K1C4Q7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Luminal-binding protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006506</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Q7"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000016">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438475" description="Luminal-binding protein 5" evidence="9">
        <location>
            <begin position="20"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="641"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="654" mass="72203" checksum="F11E26875AD60B34" modified="2022-08-03" version="1">MNVLKVLALAAMGMACARAEEAKGPRGPVIGIDLGTTYSCVGVYKDQKVEIIANDQGNRITPSYVAWDSSDERLIGDGAKNQATINPEKTLFDVKRLIGRSYNDKSVQADKKLLPYEIVNRDGKPFIQVTVKGENKQFSPEEVSAMVLTKMKQIAEAYIGREVYDAVVTVPAYFNDAQRQATKDAGTIAGMTVQRIVNEPTAAAIAYGIDKKDQGEKNVLVFDLGGGTFDVTLLSIEGGVFEVLATNGDTHLGGEDFDQRIMQYFIKKWKKDKSIDIGKDKRALQKLRREAERVKRALSTQAQARLEIESLLDGEDFTESLSRARFEKLNEDLFKKTLGPVEKVLKDGGVKKVEVDEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGVNPDEAVAYGAAVQGGILSGEQDSTLKDILLIDVVPLSLGIETVGGVMTKLISRNTAIPTKKSQTFSTYQDNQPAVMIQVFEGERAMTKDNRLLGKFELTGLPPAPRGVPQIEVTFELDANGIIQVGAEEKGTGKAEKITITADKGRLSEEEIERMVREAEEYADEDKKVKDRIDGRNGLEGYLYNLKNNVEDKLADKIDEDDKETVLKAVQDAMDWLEDNQESDKEDFEAKQKEVEKVANPIMAKVYQSGGAPEGDDEEEDDDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C500</accession>
    <name>A0A8K1C500_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008865</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C500"/>
    <dbReference type="OrthoDB" id="47179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00660">
        <property type="entry name" value="Topoisomer_IB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.15.10:FF:000007">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018521">
        <property type="entry name" value="TopoIB_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00176">
        <property type="entry name" value="TOPO_IB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="10">
        <location>
            <begin position="316"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="664"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="744" mass="84577" checksum="704E90583419675D" modified="2022-08-03" version="1">MSSSEDDLIPIAQLKQRAIKRKMKREDDDFENGKASVKPAPPKKRVAVIDSDSDSDEMPLVQLKKKAMEKKKQEVSKKVKKEETKKVKKESSSSKTTGVKRKTPTTTQKSASKVSKTSAKSSVKDEKSARVKRENGGNVRKLKVHSKSERLDMAIKAYRWWKAEELPEGIQWRTLEHNGVMFPPAYVPHKVPLVYNGKQIELTPAQEELASFYAAIPKDGPQLGNPKTAKIFNKNFFTDFKKVLGRGHEVKTFEQCDFSLIAAHLEKLREEKKSMTKEEKQPEKERKELEQFTNGFAIVDGHLEKVGNFRIEPPGLFRGRGEHPKTGTLKERVMPGEVTVNVGISDRVPICNVPGHAWKEVIHRDTVSWLAYWNENVMGGIKYVWLAASSSFKGKSDMAKYEKARRLKKYIDKIRKDYQKGLRAKDSLTKQRSTAMWVIDILALRVGNEKGEDEADTVGCCSLRVEHLSFSDTNCALTLSFLGKDSMPYNNTVELEKYGDIGKQVYANLKKFCEKKDKNEEVFNELSTSELNKHLSSLMPGLTAKVFRTYNASVTLEQELPHTIDPNGTMESAPKVVTYNDANRKVAILCNHQRTVPKGFDEALEKMNDQLDQLKSQLNDLKQMKILVAKGKSKSLKLRTGDMKEEDAATKKAQAHLFSRVPSEEQVDKKIDAWKKKIQGLELKLQDKSENREVALGTSKINYMDPRISVAWCKRNEVPISAVFSKTLREKFVWAMDVDPEWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5X5</accession>
    <name>A0A8K1C5X5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5X5"/>
    <dbReference type="OrthoDB" id="150239at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="32477" checksum="42CCFB3E29CC50AB" modified="2022-08-03" version="1">MVTTTDEERELHAWKEETRRYLLKTVDSSIDEALHELERIDFLWGRIRLSKLAVGPGVKADIRVEGHLVVSANLELKLGKPSRSTAISCALQQYCVLNQILEFHSIMQAQLSRLQLLKAFLQGEHDDLLGDDPQCDVDFFLDVARKIFQDLTKIIHDLRNAANVLRLPSRRRFPYSAYVDHSFKPSLPPEVVIEFSIHRGELLMEIFGLGLTQRAVVNIPDGCCTKKELVGCVCMCRAQKVEIVDYISVSVAIPQVEEMLVHVDTQVATLVHIRDNIKALMDCFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6A6</accession>
    <name>A0A8K1C6A6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TBC1 domain family member 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099041">
        <property type="term" value="P:vesicle tethering to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039755">
        <property type="entry name" value="TBC1D23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13297:SF5">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13297">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="6">
        <location>
            <begin position="89"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="709"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="798"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="1117"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="655"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="899"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1197"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1309"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="913"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1216"/>
            <end position="1228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1459" mass="162558" checksum="D66A6B1BC220780F" modified="2022-08-03" version="1">MPPLRTASPRAEFATNDGEKDGIFGSEPHKHGAIPSTLSEIQTSEAGTPVDYEESDTPREELQLQLEREMLKRRPDRFMIGVICRSLGGVPDRFRSSIWKELLGVARNERLHLDESISRVEEDLENQKVISADACRTRGHDAFFKQPQTIELVTKLLTFYCKSRNIRYKQGMNEVLAPFLMLEQNPPMPDSVVFQLFYALIDKFLPHVFIDREFKSLQCSFQLYRLLMRYHDPMLCNYLDQHAMTPELYVTPWFMTLFSRNLSRELVLQLWDFFILHEDPYLLHFVAYALVEVHRDAIFQSDVAMLPQVLSNITFETRERMDLVCQRALTLMETTPQSFKRDLYSVCYDGYSDAMVPFLRQLMGVSSLQVYSDELITNLMSRIGKAGASMPSPDDASAPQLLSRLLERSASFSSERFASRSSVYFIVLDCRPIEQYRECHLNLSYHIDPDVVASPDALSVLIKGFTRMKGCHFCFVGPSVPPSPPPRTSSVNPFDAISKLTRGGAGENKPEAAPTTPKEGLHYEHITVTRLVLMFLQKGFEHVSRVDGGFDELKKEIDSKDEFTKEQLLVFADKNASNTESSGFKLFARKAFERVRTMSDDDPTSAIVLPTSNEEGATEAPTPPASNPSNLAAKTKATVSTLSQKLQNFTSAAKDAVTKAPNGNEGQTHSIETEERRVVGEEEWMEVCVRTREALEKSMSYKDVVFQHGSLGILFNHSRQKKYQTIVDSLVPESQASESQQIEAGDLLVAVNGQDVSNISFADTIELVKDAQRPLMLRFHTPKKKNRVFDPADAISIPPLPPIMLSASHHSICVSWTKLQGSSTRYQLQYAKQSDYNFHPWTSVPMKQEQSAELDRSGITQCHNGTLVGLDPGVSLVFRVRCGLGDKWGPYSVSSNTMKTREKSLTDDADNVSMSETASTSSSSASPQHSPTHTAVFLPGECPEFAERGVFYFRVVIGLRARREPAFDAEKCDIILEKGTIVKCSERLIAPGTNQVFVRLCSDWNIAGGRKAPRSSLLSVGRPSVDASATSTDLDEDVDVWAFENTPEGAVVLERLPEFTETPAVPLQEQAKSLVSSILSASGIKSNPTSASGMATPPMQQQELTMSVPASSQPLGAPRITVVSAVSSTEIEVAWAPPSESEGVTRYQLQYSKNRFTAIWWSVKQDIDAETRLWRLTDLVPGTTYIFRLRGGRTDQWGPFSEGSEPCKTQDLERTASGSNLTSTSGRQSPPPLRTGSTFLDKAVAAASKLSRGRPKTPLNEASAVLLNPQEGDLVDVAAWKAELQASQPDAQIFTAIRYIPTVMTPEEEELELERKSEATPLPPRLNESVLENGEDATLERKRSHSAPLLTWNRVGERELVVTKTSLFALARPSSALTIDSTAVSERSTDALVETCRSLASLVRITSKKTIKNSVVFHFRRDAEDEADAQNQTEQLCFVVDDKETCVALVKQHYQQRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6G3</accession>
    <name>A0A8K1C6G3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6G3"/>
    <dbReference type="OrthoDB" id="71311at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="158" mass="17889" checksum="B8DCF2C6D9930BAB" modified="2022-08-03" version="1">MRMSLFCSCLSRRRSDHNERLYQEQFERIRGVYPGTDYACLLNAASGEIIAQTEIPVVNTEELARTIVTLKRAAQQFATTLTQVESQVVHVKGDDRMFSCFGGEGTILAFYTQMPGVNLELFDCNEADKTVHMINTELMRLAGMTSHHALRRAHAHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6I2</accession>
    <name>A0A8K1C6I2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6I2"/>
    <dbReference type="OrthoDB" id="6418787at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF23">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="139"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="45007" checksum="48C2193F127B7780" modified="2022-08-03" version="1">MPPRADRSRRRVSIQEATHDVEMDDDMTEREDDEQTDQSSIGLSSESPRNQTMPHSPPLAGPSAQWSPADSVTLATEDDDYRSETSSSETYSRDSSGTLTPKNVQSSYSNHRDLSTRLKHAIAGDKWTGPMFDESMIGTDVVLCVRSQQLDDDAGAVVQRRPGEGHAVEEKCFYAHRFMLAASSVPFKVMLTGHMREAVERKVEIYGMEPNIFEKVLVFIYTGEVTVDLQNVIGLLIASELYELAGLREICKSFVLYHAQEVFRDPEMVQIPEKVLIEIVEHDDLQIREVTLMEALVIWGESRVARADRPVLDILSDVMENVRFLTMSVSDLYGKVRPLVDDGVIRESLLTEALFYHLKWGTTAQGAKASQRRRPRAGTAALRKRKRVSFIQHVSFVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8P8</accession>
    <name>A0A8K1C8P8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8P8"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="572" mass="64155" checksum="9862B7096BA6B533" modified="2022-08-03" version="1">MPPRHATSPASAPLASRTKDTGLDASIVALFVGSVMLKMLLIPSYTSTDFEVHRNWLALTNSLPQKQWYHEVTSEWTLDYPPFFAYFEYALSFVAKWVDPELVQISATPLFSLRILLFQRFSVILSDTVLFYAIYTYCSSWPSVTTTELAFTPSKRRVIMLLTTLDAGLLYVDHIHFQYNGMLLGLLILSAAQFRQQKDLQGALLYAVLLMFKHIYLYAAPLYFVYLLGHHCYKPNASTADEEQRRKRSISETDVHPTIQSQHEGKASFSFFNFLRLGVMVLAVFAVAFASVLFGHPDPIAGLKQIFSRLFPVQRGLCHAYWAPNIWALYAFVDKALVLIGVKGRAGVALMSGGLVQEASFAILPNVSPLVCAALTFLSMSPVLYTIWRYPDSSLFMSALVYCMHCSFLFGYHVHEKAILQVLLPLALMAAESVNDMRLYRFASIVSSISLFPLLFTPAEQGTKILIAVAHALLAYVTLDPLLKDSLKKRRIMATAVHMHIVEKLYLGLLIGVATLAALFPFIPRIGPKYPFLPLMLLSVSCAVANLYVGGYALWLHYRKLAVVKSYLLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8Q7</accession>
    <name>A0A8K1C8Q7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8Q7"/>
    <dbReference type="OrthoDB" id="153467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="555" mass="61983" checksum="9230ECEA5CEBA303" modified="2022-08-03" version="1">MAAKLDLAERASYISSTTKNKDLDGAYTKVATPDIEGGALRAGEIPQLLSKQSFGLLAQYAAVGLIYGTLPSIVYPFLTAYLNMEGSATVSATALLTIPWSLKVFVGMVTDNFPIFGFRRRPYMMLGWSVCALCLFTMAVMPMPEPYFMKPEYRKMKVAKLVDGVHVRESAPDAGAKYIVLMMLASLGYVVADVAADGVLVEYAQREPEAIRGRTQASIYATRNTFMILSNVILAFGMNGKEYGGDWNKGMSFANVMLLLAIFCVPIIAITWFFVEEERYERTSFKAYLKTLWEAIQTRAFYQVIAFHFFANLFTNQSYVASNPIQIYWVKATNLNYNLSHILGNVVFVVMLGFTGKFGLHWNWRWVIGITALCILTIDAIFSMITVWDVFRNQWFWLGGPIVENVPYAVQFIIATFIVVELAGNGNEAACYGLLTTVMNLSQPFAATITKQVNGHFDVWNKDIMTDTHHVRTQVTYTILIAYACKIFAFSFLGLLPTQKAACQELKRNGGSSKMMGIFTVFYCSFALVWSVMVNLLSIFESTKCLAITGGCHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8S2</accession>
    <name>A0A8K1C8S2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011871</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8S2"/>
    <dbReference type="OrthoDB" id="67445at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050500">
        <property type="entry name" value="Phos_Acetyltrans/Butyryltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004167">
        <property type="entry name" value="PRK05632.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007233">
        <property type="entry name" value="PRK09653.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356:SF3">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="8">
        <location>
            <begin position="258"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphate acetyl/butaryl transferase" evidence="7">
        <location>
            <begin position="427"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="764" mass="84251" checksum="62583DE7051A4211" modified="2022-08-03" version="1">MWRLRRPLARVAPTSSAVFRTPLRRLSSALGDGKVPADSLYVTSTDMIRKTSPVLIGLSHILEQKFTSVGYFRPIAPAEGSLNRDHHVELMKSELELSQPVDELYGVSSDHALQSWLEGKEDDLVEEILTKYEQVKQKHDFMIIEGAQIMQHETSMSWKINVDLAKALGSPVLHITDMGRVVLPEDDMVREIVSRSMLGKEQVDDAGLNYFGTIANRVNTKDPKAFGIRLRAKLGAEKMPFLGFLPFDDLVASKRLNEVTHKLGAKQLFGNKQIANNVVVSDAIVATSHLKDLFEHMKKRKDGLLVIASADRSDVMLGLLASRIPGVLPSVAGIVLTNGDYPQSNTQEILRGVADFDKTGLSIPIFSVEEDSYRAANKLSRIASDILPTSVHKIQQCRNLFDQFVEKEALIGELNQGYVVNRSPKQFKHFVFNKARNVQRHIVLTEGEDIRVLQAADEVLRQRLSKVTILGNPEEIRLHAKTLNLDLSRATIIDPAKSDLLDKYSKYFYEKRKHKGVTPEYARDTIAEATYFGTMMVEMGDADGMVSGACHTTANTIRPALQLIKTLPERPLVSSIFFMCLESGVRIYGDCAVNTDPTAEQLAQIAVTSAESAEAFGMIPRVALLSYATGDSNTGPIIDKVRQATKMAQEMRPDLDIYGPIQYDAAVDESIAKTKLKAIPSGAKVGGHANVLIFPDLNTGNNTYKAVQQSTGCIAMGPMLQGLRKPVNDLSRGATVKDIVTTVAITAIQAEQMIAKQKPTDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA86</accession>
    <name>A0A8K1CA86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA86"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="209" mass="22774" checksum="CAC7815E712A1BE1" modified="2022-08-03" version="1">MAATTPKIFTPITLGGKANPIQLKHRVAMAPLTRLRAGDPGVQPDYAAKYYQQRSTDGGLIIAEATNITAYGRGYLGAPGIFNQEQIDAWKPITQAVHDKGGVIFLQLWHTGRISHPSLQPDDVLPVSSSTNMPIDESRVVPTKDGRLPLVQPRALDAEEIPKIAKEYRTAAENAIAAGFDGVEIHSANGYLLEQFLFDGLPRHKKIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBL5</accession>
    <name>A0A8K1CBL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000091</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBL5"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="556"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="557"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="580"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="608"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="792" mass="88356" checksum="5C4BECA1AD11B4F9" modified="2022-08-03" version="1">MVSAERQQMLKAVAAGTSSGLSIVGSVYILGRYWYGRRMRARASPGSAIHHVDVTKELIHVLAWMDLVGAIGRVFGVLPTKSYSEGETVSDICKLQAYVIAFGDLAPIVWNFVMALNLFRWVCIGEDQQMLKRKIKWYIFGAVLFTLTVNTVALAFDTFAAAGLWCWIALPNDHTAETYWKLGVLYIWVLLGALAMVVLLVLVKMDVQERLKGVDNEDARVAYHGVVQNLTIYILAFIACWSPAVLDRGYQAITGQEIFTLSMMHASFVPLQGFVNAVIYGKFHVWIGRHVQRGRASTKVLQRESNRPWDANRVAEERQKERGHFGSATIFVTSFDMNWSPFPPNLDDWIPANNDVYVFSLQHCLGVQQVEQAIRRHLLKINYPTGYRSITSLAGSQYRGSSQDAAVCQIVFVNNADIASGNFQFHASEDKSPCKDLFLDSSEGLNEQPSYKDRILHHSLPDTKDRIRNVKYWLCEEILTSSHKPICSIYELEVDRFFAFKNSEAALSDRKAGNMALREKKDVQEFKIKLVNLDANIWTYQTVQRPNNPLWRLRTAASESTGEQQTSTKSGVSAGDIESSYDNVQSSTEGKTRSFSQRFGKKKRMDRSNSARSIGRQSTGSSHGGPSFSNAKRGGLDTDDEPQVELVPIDPSSISTLFPLPSEDVYALQRKVYEVAHSVQSGFQTSAKDEESEESLLAYTNFRTVTWKEASMHGVMHSAITKAVNGVIHVAIKVRGGEKGQGGQGVLCIQEEDLIKRATPVIGEAEPIPFDIQLTWGGKHVGYLHGDILSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDI6</accession>
    <name>A0A8K1CDI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDI6"/>
    <dbReference type="OrthoDB" id="69901at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="311" mass="35200" checksum="0E8F4F341264B117" modified="2022-08-03" version="1">METRSSWSMRELRAIAADRGLKYYRHLSKPELHALLHRKAGGALSAGDGEQQHGEGKESSVREGEVTTTKETETTSTKEKKMKATRCSERISALKRKVEDDEEESERERKKAKKVINTLDPIMLTELGPHTFEFVRSNGSIVVYNVDSLVQYILATGDFSEPETRIPFSDDDLRRIDAEAKRAKLDERSVLEAKHNKHLFDEQKVKRDGLLGLERCAGEFITQMLEVVENDDPEEGEMQLIMTLFPSFSSIFEQIRSADKEYAKHSMNHFKAYLRGPKNRPTVDNSGLLSVILGFLDDVSNGRQAASAFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDQ2</accession>
    <name>A0A8K1CDQ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of a tri-snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNUT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDQ2"/>
    <dbReference type="OrthoDB" id="21368at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013957">
        <property type="entry name" value="SNRNP27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077">
        <property type="entry name" value="U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077:SF1">
        <property type="entry name" value="U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08648">
        <property type="entry name" value="SNRNP27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein" evidence="9">
        <location>
            <begin position="147"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="23862" checksum="CE6836AD5ACF113D" modified="2022-08-03" version="1">MDRRERSASLDSLGRRKRRSGEKARGRDRGRSRSGSSSSSASSRSRSRSRSRSRRHSDRRRRSTRSRSRTHDRRRRSRSRSRSRSHTRRHRRSDSRSPSRQRRQDDRETRKSQDEKTASSVAAKSTSESKTKEETTVLSAAHQQLSEEEQMRLLLGFGGFDSTKGKAVEDNVEGAATGAVRKDIKREYRQYMNRRGGFNRPLETPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE60</accession>
    <name>A0A8K1CE60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE60"/>
    <dbReference type="OrthoDB" id="164415at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476025" evidence="2">
        <location>
            <begin position="21"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="27553" checksum="099DB2DBDA163B7F" modified="2022-08-03" version="1">MTKSIALATSSALLVTSVAGHGYMTTPLAEFKGDVMKTNYVATIQANSIFQGKFDDSPQANAATFTAAFKSSQYKTLQDLVLDKGDPCGTTNPDAAPKPIPQDGMIVWQNPDTGEGFIQSHTGPCEAWINDKRVFFDDDCPTHFPSKPAAKIKIDFSSCTGKCMLKFYWLALHEPKWQVYKNCIPLQGAGNPNPAPAPTPSMNPAPGPTDQLPGTVRPPGGNNGNNGNNGNNGNNGNNGNNGNNGNNGNNGNNGNNSHGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEL5</accession>
    <name>A0A8K1CEL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_012784</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEL5"/>
    <dbReference type="OrthoDB" id="435607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041672">
        <property type="entry name" value="Bap31/Bap29_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18035">
        <property type="entry name" value="Bap31_Bap29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418972" description="Endoplasmic reticulum transmembrane protein" evidence="13">
        <location>
            <begin position="16"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="14">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Bap31/Bap29 cytoplasmic coiled-coil" evidence="15">
        <location>
            <begin position="183"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="139"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW61593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="273" mass="30337" checksum="BAD9C6E36BBA746E" modified="2022-08-03" version="1">MLLNHLLFWMMLSEAAVCLLLSLPVGQGASQAVIRFLSARLGGPNSTASSIGKVLLTLVALFFLSDVNTVYKYQSSDAMWSDGLRIRLLTAQRDMYISGFCLFLFLLLRLVYHSMEKNLRLEKSLGAMKKQAEGAAAGYKQLLEESETSKAQMDKLQKLVGADDKDGVVAMKKLLDENSSLTKQVESLKKELKAAEVKVDSVKKQAEGQSAAFMKLMDEKTASDKQVDSQKTLEATIAQQKEEIKALKTERDSLKSQVQDYDFMFADAKKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFB3</accession>
    <name>A0A8K1CFB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arabinogalactan-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFB3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442876" description="Arabinogalactan-like protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="11890" checksum="828CB199CB531C4C" modified="2022-08-03" version="1">MQLTRVLFALALVAGLASAKVHVPGKESADGFAPKKTIPKFHVARNLAGSEAGSAAAATGSVAGSGAADTTITAPAPVSGSAAGSAAGSATGSSVGDATVPSPAPSSAMSIATVGPAFAAVAAVYAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFN2</accession>
    <name>A0A8K1CFN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">KTI12-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005219</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFN2"/>
    <dbReference type="OrthoDB" id="9972657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30545" checksum="D291DE9B13B2DF5C" modified="2022-08-03" version="1">MPLVVVCGLPAAGKSFVATQLVDYLKQYVQEDVVYITEATVNVNRLEGYKNGHIEKMSRGALRAGVEQALNSKSIVVLDALNYIKGSRYEFYCKARAESTTYCVVYVDTPLELALERNASQEAQYDPELIKSIASRFEVPIEKNRWDSPLFHLTPEAIAKDGLMLDKIAEAVQFGKAMKAGLATQSAPVVETSFIQELEQVTTLIVDALIAHQRDGGVADALKVPKASIELRLNRNMPTSEARRHRRQFIKISQLHPCAVAAIGDLFVEYMNKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFR1</accession>
    <name>A0A8K1CFR1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009702</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000123">
        <property type="entry name" value="Mini-chromosome maintenance complex-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="831"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="875"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="963"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1066"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="179"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="512"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="831"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1156"/>
            <end position="1390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1398" mass="155531" checksum="ACE951A0870AD7D5" modified="2022-08-03" version="1">MLYKAHPHEKRWVKRMDDSDEWLVPFLNWPCGRQAVVMTKDEDTAYVAVPPTPQGDLREPARSKKKLTLAEKYALEPPFRAREHPLHTASLLSAYTTDWFQPIVALGYQKVLEKDDIWPVCPGDTCDALEERFKQHYDILSEQQTDPATRNGNWWVSRFGVALLRTFRMDLFNIYGNYALYVAMMVLQPFIAQAMLDYLNDEENIFHIKSGVVLVFLMTIVSLIGVSCLNYGFFVSSWIGANMRSIIMDVVYQKALRLSSTARQKYTTGEIVTLMSVDAERIFGSVIQGPWILVSPLAFVITIVVVAILYGIVPAVAGAVVMVLVLFCSVKLGDRIGEVQLKLLNVVEERVKVTSEALQGIRVMKFYAWEDSLARRVEKMRSIEVGLYRRFHYLNVINISLLFLLPMIMCAVIFGIYAALEGTISVTDAFVMIAMVNISRYGVNQFPLAIANLSQAKVAFRRLDTYMESDELGSSRSEGKLSNGAHSENGSISIRDAHFIWTESNTSSVPEVVVDDIDASTAEAVPEGSVPSLVEAQNVFSLEGVNLEVEPGSLVMIVGTVGSGKTSLLNALLGEMKRMSGVCDVNGEIAFVSQESWIRNASMKENILFETPFDPQRYEQVLEATQLALDLHALPNGDQTEIGERGINLSGGQKARVTIARAMYRENYDILILDDPLSAVDPHVAHAIFNECILGLAKDKTRLLVLNSHYDLLPHADKILVVQHGRIVGDGKYGEILAQFPDLGVQTQKMNSTEENVIDEHESVDVEKVQGHAAAHAAATAVVVTTPVVVSGDEEAKKDEPARLVQEEDRVKGKVSGQTYRTYFDETGYNGVLVVVVLVLIFGIAQTIKVGGDWWQGYWAKQMPRRGVDSSYSDVWYICWYIGLIVVCTVVTLARGVVLMESCMRSAKNLHDELFRRVLNAPVNQYFDITPVGRILNRFSNDLDQVDSNLPQQYHSLFQAATLVLGCLVVCGVASFWIALSYIPMIFIFVITGLYYKRSSREIKRLEGITRTPIFNLFSETLNGLDTIRAFQMEDKFVALNKVAVDDNASFYFNYWGAGRWLSVRLDWLSVVIIFVVSLYIILSKGSIAPTVAGLSITYSLMLTSMVQWCIRAVDLTDNAMTSVERLLHFRTIPAESNDSDCTPINPEAWPSTGSIQFDNLCLKYRPELPLVLRGVSMDIAGGEKVGICGRTGAGKSSLMIALFRITEFESGSLFIDGVDISQLKLRELRRSLAIIPQDPVLFSGSLRENLDPYGDYSDEAIWNVLKQVHLADAVTKWGAGLEFIVSERGDNLSVGQRQLVCIGRALLKDSKIVVLDEATANVDSATDNLIQATIKETFRHKTVLIIAHRINTIMHCDKIAVMDAGKVAEFGSPAELLRQSDSIFSSLAQRSAGATEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFU4</accession>
    <name>A0A8K1CFU4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009559</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66977at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="876"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="1128"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="673"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="692"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="730"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="806"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="829"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1918" mass="214848" checksum="0BFD3C7E801F0FA4" modified="2022-08-03" version="1">MGVRGLARYCYAHETQTALAYEQLTDVTLAVDFVGFQFFVCHEVAQEIETQRHMPTALWLLLGGCPMRLEQWVEAWLARLRTARIHLVFVADPPQCFLGRNHSKTPELLDRAQQKADKLKELYSSLFDMKATRGRESVRCELKTAQQEQMRQYLQETQGCIPFSREKLREILKKHGIPVTTATREADEALGDLVRSAQAFAVLGNDSDFLCMRGVQYIPFSRLRIDERTGRVSAHIFFPDLVAASLQLPSHQLADLALLCTNDATQQLDAQFKLAQELGFPRSTSPDAFVTPEAAATWLRKQKLPILDNKKLLALLKRHTRLGAALLDFYQFYGLGEEVRQRIRVSNNATNGLHPKELERLRGLIDQHQLSSSLVDVLHWKARKLSAHFDLLPVIRPGKNVLEMLSPARRLLYHALRVDTVNESFYDGIARQVKELTVSTPRLVFLDKFTVPSANRSLAEVEQAWRSLIFTLVYQNERGMGNATFLWKLMSRQSTSIKSLVASLLVLYKCDMSYLDASDRVLSTEQLEVLLLTSMVCQAMKPGRLAQAYDFEPVDFTLDWRVYVSARSFIEVLRAMHFVRVLLGEPVALSSCDSIFSAEIFLAVYTIISSTREADTTSGDAAPTSGLTRSQVDSVLCYYITDMKDDERHSKWDDFCQIRAALSRLVELVPATTPEAPVKTVQPKREESRGEEAEEEADEEEEQENEKEEGTDDEEDYYATFVPGFKVPGEKPPVAPSPDQLPPPLPASNGRSKKKSNNKKPAEKPASNGRSATPSAPAAPPTTPLSILTPSSVTKKMTASQRAKVSTPRSSGRRSPASRDSNARKSSGNTPRNNTLTETTTIQPPLPPGDAIPQPTNPLQGLLETLPVFAHREQILKNVASNQLTIIQGETGCGKSTSVPQFILDESLRKTGSERPVNIFVTQPRRIAAIELAKTVSQMRQNNEFGEDGVVGKVVGYRIGQKLCATEKTKITYVTTGYMLERLIHDQKALENITHLVIDEVHERSMDVDALLLLLKLQFEKHPHLRLIIMSATMDAKVLIKYFSSSLPMKLIRKSPLFVGSKLFPVENVYLDDLMAMYPDLLLSNRNELLRIGDELARVERSGAGANGDLGQSVLLNVHDAQLRLIPTMLQLLIAYHHQQSAQPQCILVFLPGIGSINRLYEELTAAFPPLWHGIHMHITVLHSTLELEQQQMAFQPLGGRSSKVILATNIAESSITIPDVTHVINCGIEKQIQMPNAGSTHAEVLIDVWCSRASVQQRSGRAGRLMPGVAFHLFTEDFMQKSMSEFTTPEMLRKPLDRIVLQLKGKLHQFGVPSDLLKQALDVPDLHHIDGAYKLLALHGAIDGPDEESARITAFGSFVCHMPLSMELCRLLLTGTTLHSQSMSPGRALTTPYMLAHVVILSAILANPDLFVMPSWYHLQSATKYMSEMKQNLKAKLELDGGIWSEPLAIWRFYMKTMGKHTLTSRPSLGSALKDYGLSFRRFQALNLLISDTCERLATLARQGALQLETTSIDMLTRLDSYASSQIIDRELMAFAESANKPGCYELEVLRFLVIHNYSDQLMGGIIPESGHYEEDEDLSTYSDRVDLSVIKDHMLAFFSLSNKERKDLFTQLARKAEGAAEEFTSIAYADSQVSIYTTAGLELETPIDEVHSFDGVLERMSFPISLLYYIQDHKFPVNFGRMVESKGEKKEQTFRFRVKGSSGGSVNWTQSKDGVRVTIGGRSLFSLPVRSLDDDELDVITPRRLLAVYTDRLFTGTEARMFCSKCTLLPPDALGYHAMVLLASVRAGTNIWVQIDKKGEYLIDVRIDQQAITLPKNVVLLASMLKKVNVLRAAFSAALQGKSSTESAGSSRQRLPVEVVMDLCDDENIAQEITRADARSREYELRKVMMIEPTQAELRALREENRTPPRFPELVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG37</accession>
    <name>A0A8K1CG37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG37"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="35654" checksum="9A70CB17E7BDED79" modified="2022-08-03" version="1">MLASLSFGARSTSTSTSPTAATQPKMGAERQRDVLFGAGCGLLCFGLFPFRTLATTTAESTVVEHAAGSVVETGFDEATQLLSLAFAGLGLMCATLSCLAVPRAALRWMLPLLLLPLLLTSTVSTLRIYHHFTASDLVGMVSKSGFSVNGELLLEARVNHLYCSASIQNVCARDTVDQAKAAFPTLQWPSNAGEEMTVAQACARDFVMRGPTSLSTGCRVCRQEPVIDSDGDVVLKLIKPSPAASKWCGEYLTHSHMRGTRRGTPYRHHRSQVLDNLDVLYANRVSSVRLMMVLEWFAFPAIVALLWWCCVLSGKTSTSSARIQLSSNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGD2</accession>
    <name>A0A8K1CGD2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005657</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGD2"/>
    <dbReference type="OrthoDB" id="588261at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="17254" checksum="A692717FC121135F" modified="2022-08-03" version="1">MSLQVLKQTATKASLAKTVATASLSTSAPTYTERQARLGRPVSPAVTIYKFPITALSSITNRATGVGLAAGFTAASALAAVGVDLPSVIYAAQDVIPGFAPISKFLVAFPITYHSFAAARHVVWDKNPELINKIDGPKSSYAIFGAATVLSLGAAAYTIKAPEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIC7</accession>
    <name>A0A8K1CIC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WDR5-like beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002716</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIC7"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059122">
        <property type="entry name" value="Beta-prop_WDR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25175">
        <property type="entry name" value="Beta-prop_WDR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR5-like beta-propeller" evidence="4">
        <location>
            <begin position="15"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="178"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="352" mass="38358" checksum="AAE9159FDE020933" modified="2022-08-03" version="1">MASTTTPTWTAQRSITAHSKPISSVKFSRDGSLVATASADGIIKIWSTTALLDASSECKPSVTFHDHDQGVSDVSWSPDGAYIVSASDDKTVRVWDVEQHKAVSVLGTPTHSNSVLFSGLPMDSDALAAHAGDDTDDGHTSFVFCCQVNPQGTLIASGSFDETVRLWDLRSGKCLVDLTVHQEPVSCVDFNCDGTLLATASYDGLVRVWDVATMQCLREIILDPSVPVTQARFTPNSRYLLVGSLDHQLALWDYTTPQKPRCVKRFQGHVNQKFCLSAACFQDPEGDMTRACVLSGSEDGRVVVWDIEMEEKRDEWVVPGETKEPVLGLSVHPTEPIVVTGSGRTLTLWRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIQ4</accession>
    <name>A0A8K1CIQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIQ4"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="27"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="37371" checksum="80089EAD6B747E6A" modified="2022-08-03" version="1">MAANTNTTYAAAVPATYRAYVHEHFGELAQELKLRTDVPQETLKNDQVRIHVHAAAINPIDYKLIEWGARMLPFAPTPERPFRIGFDVAGVIAELGSDVTDLQVGDAVLAMGDFVTKGTFAEYVVIDAKYVAPKPAKLSFQHAAGLSLAGQTSYQALVAQGQLQQGHRVLVLGGSSATGSLAIQIAKALGASFVAATTSTRNVEFVQAFGADRVIDYTTEKWVDVLDANSIDLIFDCGVESASWNDDAQRVLKHDTGRFVTIGQEITPIESPVGATYIRFRTQPSGADLLVLTGLVERDELRVPIDSVFGFEDLLGAFKSVKTGRSRGKVILEVVAAAQPRALSLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJE2</accession>
    <name>A0A8K1CJE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJE2"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047767">
        <property type="entry name" value="LBF_2804_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="758" mass="85669" checksum="34E1EDA8BDFAB41B" modified="2022-08-03" version="1">MRPAGRRVALAQRLSRTGSVVVKLGASYLEGLMEFFQLCDADEDGKLIPNELDLLLAMLGVLATKSSWNLQRSPSKVFSCTTFDQFLVQYGRRLHSEAAPLPPVHFLRSCKQLKSGFKRCDTDGDHVITTTELEIALQKLDVVVTDEILQHQLALLDSNNDGTIEWSEFLRAAWRNASSHAAKSKSTVLLLDTLRSVPAPAIVHRRPSTPQGRGSGRALADSHGRPPGKKQLNKSSNASRLLYKLALRAHLIWQQQPDEVLRPAEPAQDTAARRHRTLPVKSRVEHIGVRILTRISMQQVSNMKRVKQDHTNAAQRRGARATLPARGPHSMALPSRKETRTRLSPDVRRRVFAIEFIAVILSALAGIVSGLVSIKIESVVPIMRQFDILSGTSSYYLVVLGVNIAISLVEVNLMYLTSVICAFRMTVATRLTLYPQDAEREFLTRAIARAALQVSHRTEKLFGLDPMKDSPRLVFFLSFLMFRSKRSVIKLLLKLFIRRVFWRAAAKATLSLMVLPLNAILNAWTLRRVMRNCRVTIIGPPCVTALMEEFFSRHNDQLRPFQRVDYLRVLGCAIVCKRSIHPNLEIMVHQLRNKWVTTKQWALADGCVCISQPDDPCPVHQLDDTDRFFASLLLYSSQRHLPITPDLPVVQHEQSMLCLLILAFVLDGNLTLTERRLYLRACQVARIESDWPGVFRIMRDFLNGKGIRLEAVYAMLKPVPRWQIPKDELSVKSSKWEKMSLTEFGLYVADRLSSLIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLJ1</accession>
    <name>A0A8K1CLJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 16">RING-type E3 ubiquitin transferase RAD18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_009032</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RAD18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLJ1"/>
    <dbReference type="OrthoDB" id="206574at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097505">
        <property type="term" value="C:Rad6-Rad18 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000172">
        <property type="entry name" value="E3 ubiquitin-protein ligase RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="28"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="201"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="362"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="412"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00082369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW64865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="445" mass="49054" checksum="131202099CDED9E5" modified="2022-08-03" version="1">MDNMDDMDEWLWPEAYGELRQLESTLRCLICGDFFHGPVLLPCSHTFCSECVRRFLQSRGAHGCCPECKQPCAPRDLVPNRSVEKVVTLFKQVKPKVLPVLSNTKQAAVTSTTQDTTQSRRKQGGASSKPPDRMPLLSYNMMKEKEIKKLLESIDIRVPIKNRDDIIQIHKEYVLLANAQADSSNPKSAAQVRDEVMRNYRARQQEKKQSSRKSTEAGGLSDQMKANFEKLKQQVAARKAKQASGGDGGDEDDATKEDQEEDAEDHDEEVEGVWRHVKALKTNTEFYIHSTTHEIRLEKPAEFEELQRRAIAEASSTSVDEIDLTGPSTEDVKTVDNEAIAAATASDDDDFEVLSPSKSIPAFHISPATPLSTTKTPHRRAAPTPTSSGKKPRLGNSFFSPGSGASTPIQESSAQHAQTFTASASASAEEDMVVMMPSASPSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLU3</accession>
    <name>A0A8K1CLU3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLU3"/>
    <dbReference type="OrthoDB" id="10660108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="26482" checksum="47ECA9B4C74C052E" modified="2022-08-03" version="1">MTDDEPLFASQDTDYDETSSSKPPVARSRGRKTTSGIPRPTKIPRLGKQTSVVSAEANEATPSVASSRETTPFSSPTRGSRLRGPGWISRKRPREEHGTVEAAAERLAQELSHADAESVQEDEEQRRERELTVAKHLQRSLRRDAMRLKLKSDHLQDECEFYYSMLTTLENATAAIRATHVRRITEGDEDPQLLHVCELADRIQTIITAPQTTQDVDTPPRTTQEHNDDANAPTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM17</accession>
    <name>A0A8K1CM17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Golgin subfamily A member 7/ERF4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM17"/>
    <dbReference type="OrthoDB" id="161885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="3">
        <location>
            <begin position="50"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="203" mass="22975" checksum="A5A067F96795378A" modified="2022-08-03" version="1">MVATSFHAASAENDRVIAPTTSVDGQKGAEHEYGVIKLYPTQVRFITGIARAYDDDFPPELRLLVKEPDFETAINQINNTLKDYWPCFFCICCGYTFCPCTLGVSLVCPNLCIKDAEQYVHALIGRINKRHCFQRVGVEWRLARSCGRSWIEISYPMTQKPITEFAYQTNSLHANTIPVSLYPPSYNGPNTRRTAESRLIVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM48</accession>
    <name>A0A8K1CM48_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM48"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="137"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="398"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="524"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="63298" checksum="1DF427CFAABDBAF5" modified="2022-08-03" version="1">MGNGASHKHQYQERHSDSRLSSIRLDGSTVVVNGRGESNTVTLRLPSHPMHSDENGPHAVRMRTRSLPLPDSARLPNALQPLHPVKETREDAVSSSTSSPGGSSYDIVASQEKTPRPQDDDDDYEDEQFEEEDRIEWKKAEALGSGSYGTVYLARDENTGALMAAKEILVADESDADVQNASREVSLLRSLHHENIEWVPGGNLEQNRKRFGGSELVVRRYARQILQGVAYLHSKKIVHHDIKPSNILVDQYGVVKLADFGSSRLMSTSTVVNNESLRGTPNYMAPEVIQQLSRSPKSDIWSVGCSVLRLLTGRALWGDKRFDSQIALLYYIANLSELPSLPEDLSDSARSFITACCAIDPTMRPSAEELLLHPFVNGSSHFPTVRAATAPIDTKHALVNPHRAPSTAPASDSPKTTDIQSLRTSSKSQLVSSRFPSLGIFDEIDKATVSSHRTKSQTKGGEPTEPPTRVVGTVEHDEDEPMYTLDGFVDPSIVTGRSQNQMTLTSQLDQTSNGFTWEDLPIQTDAARVELERQRERAAEAQRKREERERQYQEELVEYRRRMLQPVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMB1</accession>
    <name>A0A8K1CMB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMB1"/>
    <dbReference type="OrthoDB" id="10064407at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018717">
        <property type="entry name" value="DUF2241"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39199">
        <property type="entry name" value="BLR5128 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39199:SF1">
        <property type="entry name" value="BLR5128 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10000">
        <property type="entry name" value="ACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2241" evidence="1">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR ACT" evidence="2">
        <location>
            <begin position="74"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15095" checksum="90985248778A6A1B" modified="2022-08-03" version="1">MATGETNLSTLLRSMAPELHEGDYVITNVTPKVFATLDTSSVLCMFRESPSDITVVLGEENAKRFGLPTTPVFGWITLTIHSSLEAVGLTAAFSNALGAAGISCNVIAAYYHDHIFVPKQDAQRAIEVLQELARFHGADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMP7</accession>
    <name>A0A8K1CMP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMP7"/>
    <dbReference type="OrthoDB" id="157595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="32795" checksum="4DDE0FF037117FE8" modified="2022-08-03" version="1">MTATKVFLVTGATSGIGLECARTLAKIPNAHVIVAGRNQQRVDDAVADIKIAASRNTVVEGGVVDVSSLQSVRNFADTLLQRNLQIFSLVCNAGIQVTKQSHTVDGFESTIGTNHIGHFLLVKLLQDRTKRVITLSSETHDPAERTGLPAPNVSDLDQMAKGYAKFNPQEAYTTSKLCNLLHAKEMARRFPNGPEAIAYSPGLTPDTGLFREQPKVVLKIFMFVLRIVYWFRGERMSTSVYSGAYLAGIAAADALEAKGWHNGDYLSIDRVVNASDQACDKSLGKALWDKSEVWVRPFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMW2</accession>
    <name>A0A8K1CMW2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMW2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="199" mass="22142" checksum="A5328608368CA761" modified="2022-08-03" version="1">MLALSASAYEEHKLNLKKDEVSPSKVCGGYCSNYVNSSGTSELGMHAYQAPYVMDIHSIPVKPVPEATSTAFHDVPPKLESAADAQQTYRVVRDAIVSQAYAYHCFSDWRINAAVMVTGEELEIHVAVMRVVPSNCIRVDFHLLQGDEMQFLYAVTTIQKQCRAIDMRHLGGPDSRRNVTLPQWSLRSDEFTTSSSLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN01</accession>
    <name>A0A8K1CN01_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN01"/>
    <dbReference type="OrthoDB" id="59758at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35691">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35691:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="103" mass="11597" checksum="C562735AE24E8C5B" modified="2022-08-03" version="1">MFLKRLEPEDKPKGNEDSTELQKMLTSCMVNRQILCCVAGVLIGIPISIQRKSYKPFAILGVLGSFVDYSIPYTNDCRMIHNAMQLALQQERQRSIEGSDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN04</accession>
    <name>A0A8K1CN04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN04"/>
    <dbReference type="OrthoDB" id="77369at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="203"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="854"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="876" mass="101583" checksum="407BD811393F81F8" modified="2022-08-03" version="1">MTQVVEIAGVGRVEDVLSAVRPLFQDLEDVKPLCRNIHGRLERLWERIRGDDARGRTHAFVMTLRAFQASVRRQYAKSAVVQIVTGVWFLRQLDQCHEEILEMCRDDEGLDMNEWMEDWERHRQTIEHAFMRRVANKDMLRGELVDEDSTEILGLTLYQQRKYGKEAAYLDKLRDLLLQDPTVNASVKLPSWFLSTDDVAFHPDPFVCPESGSLGTVHHGTWNESTSVIVKCIELVVPTADRVKKDWKEVDVWSTLQHPNILRLYGACHVSRPAWIACEEAAHGNIREYLDNDSTRRSRLWRLFHDAAIGLTFLHERNIIHGNLKCSNILVGDDGRAKLADFGMSDLQQAIERRSWLDGETRQWRERRSSISAYPTSSWQAPELLEAAKRGEEIVTSFASDIFAFAVCILEILSLEQRWGKNEQFLAKCLNTVRRPQNISDEEWYLIKDMCSPDPSQRLSIQRVKRRMYLLAEAEARRDFQVHQTPGEEDDIPPSEDVDKHRKEHEMQRAAQRLQRELEDLRRKVREQERALELALERRRQAEGGEKTRRKDSVEPKSTRTRRGDVISVSMTTKKLLRYLRWGTPEEQSDALDVLVDNPRVHDAVNVARHNGLEVLIAIIKHGHSSEFRITALDLLQRITTVSNGIYLNAVLEHGVTQILMSVLHYRLVPVEQRRAAQFLLVLSVKSARARSFFVQNSGVELMLKVLYESHQILIDEQFRATCDHALMEEIHKFLASQAESRAREADKALENRQANRELAAQKYTEAIFLDHRNGRYFARRSEVYSLLCKYEYASRDALQCIKRLPDYGEGYFRHAMALYGARDVEQAEKALRLGRQRDPHYFTRDRLQQLTFHVPQQAKPRQETKKRSEAGSVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNB1</accession>
    <name>A0A8K1CNB1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNB1"/>
    <dbReference type="OrthoDB" id="158074at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="110"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1075" mass="119517" checksum="94ED5E7A5E15614F" modified="2022-08-03" version="1">MDSSTVFQQGRSLLNEALSPSSKRLLQEFFEAAETDVQASTVLEALVESNARETAESAPGSRSSMGSLRDTGRDRADSTRSDTRGRSQSTSSAVRKMVATSVFAQNSRTFVQIQCDKRPFGLELDVNGRQEIIVTSLVRGSNGKGAVERSGLIEPGDILVAVNDDMDGLTSVEATEAVLARAQLPAVLTFRRVAVVKPALGEYTRKQIARHLQIHENSIVEKYGADDAAAMIKACIDVLDDRKSITPLMTYVGRVEQFLCPSFATPAVKRQTDLVTWMDRIHAYVERKHKDQVKKWNAMKSSNFKRIEILGKQRESIRTKLESMRSSPEMLHPDNREVWQEFIELRHLSSQMSKSIEQAKQEHFLPDFEHYALRFGSEGVYIGLGDLWISSFRAKFTVETRSNAPHIFFHLSTPSSSGLQLRITNFKLSTEGRLPSFQCDELNIEAQLVADVPFVFDAISGWSVPADDLHVKLESLRYFERKATSVKHGVDHDTVMKLFINRLLPIVVRQAAQNLFAVEIGPLLETRDAQIVVTGEINIQGRPLDLYDAPLNTSKTGGSDHELSEEARLLVGLSEDEGDAICKVLKSVETGFKKRGHVTNEHGNLSIRVLTHYFDQFRAFPHLKTLLLVLWQQSIELLLSSPSESESFPSTSSFAMISSNLAQLQQYPVDISVSLSDLTFRLDLCEAAAVYYTTLQRLIRNKMDSVSVGLSNMEAMKDGTYLQNQLTSLDSWYNKITRVLSYVTINVDDLGVVFRGGFPAGVQSPVLFEAQDLACKGPCTGSFTIPLTDLAKLQAPRPSEAPQSSAKTDSLTALLHENNALIFSKFFLRSSEDDASDDSDQDGFLRRLFASDRVSVSVQNTSARVLFEVPTGDTALSPGETYVPFAFTLATGSDDQPTLRIETGEHAKCQYKAEQIRVNGTIGELLGPLLSSSSVWSEYADSPFFSLRFHFFVSCQVTREHIFWSLRSASLSQPKVAQIRHRFSLGEFLQDLGMVSLVDNAGDAADKNARRREDARFRRALHRKLGTNGQVAAYTTLSARETLFSATTEDMEQRSEAFTTSEMDSDAGQAASTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNB3</accession>
    <name>A0A8K1CNB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNB3"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001158">
        <property type="entry name" value="DIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00778">
        <property type="entry name" value="DIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="1">
        <location>
            <begin position="219"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="395" mass="44137" checksum="9D74E0F4B5F96D94" modified="2022-08-03" version="1">MANAGVLCRYFFQAMLVDEDAPPEDYASSLLLSPQPTLAELRRAFPFVGKYHFRLQLATKDGSYCWLDLTDDKRVLPVTRGEIRVKVLQVSAEADESEEEGPEWVDIPEDRLYDAYFQTHYPANGRRVDNNNYNGGGSSGLSSTQDVGAVLSGVKKALASKMKQSGLGQTLQKQSAKMWDKVTGGVAGSSNSPPTAAALSQLAKLVGAMKAPLSEANREHMELLSRLWQSCFEPQPFAPRGQAWAQLGFRREDPLQELQCLLPLQCLVFFHEVHRNVALPMLNEQAIPNHPDTYAYGLVASRIAYVVADILQLKDGACLGLERPFWRLFEDPIAFFELFSITFRAFDQSWKTRSGKSAEVGFHLDFAADFAQEVLRRGPESVPVLVDYAHQMLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNF9</accession>
    <name>A0A8K1CNF9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000021">
        <property type="protein sequence ID" value="TMW66565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNF9"/>
    <dbReference type="OrthoDB" id="166529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="155" mass="17953" checksum="1F1ABD7777CB325A" modified="2022-08-03" version="1" fragment="single">AQELESIATAITRQQLSLHKQLTTVKNELRSVLHDLAASKEELREAQSRLNEIDAFLDDVAVELEELQQSEDANEQHLAAKENEQEQLMMEREDEVALLVQLQNVHDLHLSVATHLRQMLVHLMRELTKMRNQEQLLAMLALRSGVFKLMRRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPG5</accession>
    <name>A0A8K1CPG5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPG5"/>
    <dbReference type="OrthoDB" id="27267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428803" evidence="2">
        <location>
            <begin position="22"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="349" mass="37492" checksum="291F94F5E38EB113" modified="2022-08-03" version="1">MRSFVPIVLSLVALFASIVRADNCSYALTAFSGSEWKITCDNDTDIADATEFDPSLLTTIRIGKYENVELSPKTAPQPVEVHVPTSFAHVGPLVSSKLTIFNLQRDAGIKMTSAVEFDAEAFAQMTALQKLTLGFYNISLTEDSWVFPPSLNEITINHGALTTFEATGVNGATLNITKLNLRYNKLQRIPTVVFTTRSLIFADLFGIDFPPLQMSRRRVARLLRLIKQGKILLGKIADFTDDCKGEKQTIAAPSGNYLICVSESDDEGDDLIVEDDGSATESTEASSTDGSKPIAATPTSSSDDSTAGAPSSNVETPTPSAGRRCTVQLITALAASIVFLAVHCLPSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPK4</accession>
    <name>A0A8K1CPK4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galactose-binding like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPK4"/>
    <dbReference type="OrthoDB" id="10052260at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16160" checksum="C858E29BE19A3FF5" modified="2022-08-03" version="1">MSPRSLVSAPTTCRVSSVLDRNKTLYGADHMLSSDVTTCWNSAQGSPQQILLQFHRAVRIERLDIMFQGGFVGQDVDVRFKRSSGAEWNTAEHVDVDPEDTNDLQTFACALDDVDALQLVFKRSTDFYGRVIIYRLDVLGEDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPK9</accession>
    <name>A0A8K1CPK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_011052</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPK9"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="334"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW67432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="43367" checksum="AE8578BB1E865D30" modified="2022-08-03" version="1">MPMTTTSGFPAAGACAELLLADQKDVVYENEVKNLLRELLERCCGTHLLSQLLPELTSLSSLLYYLLVLGRKRPQQTLGEEYCDMMRVTPVQEGAQQLPAVRNVRFARHLLWIALAVVPQYLSSRSQTGWLRLSQLTWSPRERMAQQLRERQAAAAAAAAANGEDAVRAPAPKLTLTKSLLSLLDRLVAAIKEFGSRLEKKLLPSTYEFALAPLQNWLSQVHLAAFYVAARYFHFSKRLASIEYVFVRKDVHPALNLSLLGYLMFVRLFSTAVGEMKRLQKLYKDDARQRLGEMLMPGSQGSSARVPTSPAESSLAPEPVPSSSTSTSRSRRKCALCLGERTSPATTPCGHVFCWTCIVGWCQKNKAECPLCRQETHPQQIKCIYNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPV2</accession>
    <name>A0A8K1CPV2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPV2"/>
    <dbReference type="OrthoDB" id="157379at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26287" checksum="14C9F0C05C426DDA" modified="2022-08-03" version="1">MVASKRGAALHALVLGGLGAWLTFAFTNPLGQSWTLKDYVFVLAVIVAVFYNRLSTMKYENLMQIEHRKKRQSVQSLQRIEWVHGLPRQIELNKGTWCKDSRAALKTMEKLRQVFTHGGVQFVALTQEKREELAAYEEKGRGASDFQPLEEFSFSIAIEDGLMSKEYLVRFDIYHIPHMFIIGKDKVIHWYGKPSEKGIEGRIRDCLLADNTPLNAESFAVADVHMKKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRB4</accession>
    <name>A0A8K1CRB4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264753at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1377"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1421"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1513"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="1795"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="262"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1264"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1307"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1757"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1264"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1280"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1307"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1332"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1768"/>
            <end position="1778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1950" mass="219079" checksum="2472CDB3067882AC" modified="2022-08-03" version="1">MASVMKPPERVNAVRRLSKLPSRAEMLAVTALGISGSPGDTSKRRQSISAAPSTPAPQQEEKTTEKSSSPTSKGTHKLQQLTKLKIMTRSHRRRLLRKRNLSSTAEGEDEDNGLPGELVDPPEPEQKTERRAIGTFETKDVTWKAVIQGELEKFMYPSLRLESLYDTKHPPPSRMHRNDPVSASMPSPDQVDAVMANATNMQWELEKRYKNSTQSGPPNGHIRLDEDECKRLQFDRQLDTAEGLLRKQEVMLLDAKRQQRALESLSTRNKVSSSETRSNVSEQETETTNQRDRGFSLYEPHIVNTPQLIPRLPHTRKIIKEIQRHSSKQGQIKYYADKHHLFAKWKKLQVSELHKIPATTTDNSDDGDEEVDDTLQPFGKLSPRSLFFHECAKKNVLPEPIFSRIQDEEVTRPVLPTRKPTTFSSIASTLIQAVHEKHTNHEDLVPTADGKYSAKKHHLALHLQHFGLGDRKLDALSTSLQHFQSIHALDLSNNRLTDASIIKLLESLEVASTVRPVTPGSKRTRLGNDLRVLNLSQNTIGVAGCAQIARFLGICTSLTRLDLSHSSINGVEGIGPLTAAIESHRTLQVLNLSYNNIGYICATLVGDMLMQPSCAVTELNISWNKICKGGAIAIGRALRTNTNLKTLNLAMNRFSDDGAEQMAAALSMNSSLTELDLSRNNLGGRSAIAFGYYLRTNRSLQHLRLQDNRLGAAGAKALLHAVSLGSPCEFHMSAHDVESLTGQTEAIFDVMLPSLLSPYKLNLGDSPYDSAVAQELIDATAIHKRCKLTDVTFTDNRIAKKPVITTLTTDITRGCLVDSNGKAWKLPDYGVLSATATYSPPPLQATTHLDETACFALIRIIERGFSSRERTSLLNLALSDLWMSTKLASLFVSRLRSSIDVVEIVGRLWSCLVDGECVFDFLQTHLTAPERRRLIDTFGVSMIQFTCANPTGHWSLDLGDRGQRKLAMWFTIINAHEANISAEIHSKRTDSSQYGKSFNWRNVRYNRKNMRLTYEFFDRLPFTGLLEFDYVSTVRHEDFVAMNATVVELGDEQLEALLQRVGAEVCSIYIPLHKRKDLKYQLVFFHIAIANKFLTSTQAHRVLQYFPKNYETLRFKMLLAMHRMLIDMENLCDLLERLTLVDRKRLYQTLGYLNVVSPLHVDMDFEVDFERDDEKMLLRALVDLSMSCPMDMIRIESERSTVLVIYSMYQTNSVPAEGRIFFRYVSHPIPSRSDFLRVRLQLARHFLCGERLRLYIENALSTPSVASSTPLAPTNAGTMASPSASSGPDDAPLQVAVELIERDAMAKMTEDKKHARDETEDATATLERREDAQDEEDDDDVGPMPMAPAPAAKKRRKLQFEAEYLKNLPNAAMYERSYMHRDVVTHVLVAPETQFLITASRDGHVKFWKKMSKGIEFVKHYKAHLGEILGLSVSNDGLRLCSTSTDQNIKFYDVLGFDMVNMLQVNDYIPSECCWVYKKGAIDAKIVVADRDGPSLRVYHAEQATAEPLHVLEKTHTAPVTVLAFNPVFSCVISGDQRGHLEFWNTETYKSPGAGVVKFKFKGETDLYELAKSKTYATSIDVNSKGDSFVVTATDSQIRVFRFATGKLRRKYDESLTVFEDAQAEDSLNLDAIDFGRRSAVEKELAHVNAIGNCLFDESGHFILYPTLLGIKVVNLETNKLVRVLGKVENSDRFLRLALFQGKPKVNTQLERQLNASKGLKSEPIVMSDAASRQTLIDPTLFCTSFKRNRFFLFSSREPEEDDEEGEGTGRDVFNEKPTLEETDVVAQASTAKKLGETVILHTTMGDITIKLFTKECPKTIENFCTHARNGYYDNVIVHRVIKNFMIQTGDPLGDGTGGESIWGGEFEDEFHRSLRHDRPFTVSMANAGPGTNGSQFFITTVPTPWLDNKHTVFGRVEHGKDTVSAIENVHTDKHDRPTEEIKIINVDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRJ0</accession>
    <name>A0A8K1CRJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRJ0"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF39">
        <property type="entry name" value="GLUTAMATE_PHENYLALANINE_LEUCINE_VALINE_L-TRYPTOPHAN DEHYDROGENASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="659"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1051" mass="116833" checksum="C34CD36BE3E4261E" modified="2022-08-03" version="1">MLQATKFRQLQPVRAAAQSRGAFASLINAFSTQSGQTQEELLAALNGFQREAADKTVPWFMENMPAAYFRAINEKERLQHLNAITALVNAQQPEVMLRSSDNKVYSYIRSGANYPGLLANVIAQLPKSVDGGELARVKIFTSMDDTLGVDIFRFGYQEPFTGKTEAEKSARDSVQKFMADLQAGKYKGQEGYPAPGPYFTPEAVDEYLHRCNSMYVQFSNPRRIAQQIELFNRVKGTEGVAVDVEHGWENRSDENKLSGGNAPQTMLTIAASNVLARSAMQKAATYLGLCDLNVVRAHLDVVSDHEDNNGHVSMIRILVTPSEEAQKSGKAFEWDKIVGNLKYLKWLDDKPLRLVLKYPDLGVSRAEVIYAYSNMLHGVLAKKDPFAYSINRILEVVEHPQHLPIATQIADLFMDKFDPTSPKLSDAEQEERVSQLKVDIRSNVEAEDAILLLNTMVDAVVGTLRTNKFIRNRYALALRMDPKVIGYGTVGKDIPYGVFFIYGRRFKGFHVRFRDISRGGLRVVYPNSKDAHALESARQYNEAYNLAFAQQLKNKDIPEGGSKAVVLCDPIVGPIGDIAPRDFIIRKSVKAFSDALLDLNTTDPEVKKNIVDYYGKDELIYLGPDENIIPADIVWMTKRAGYRGYPIPRAFISSKPDAGINHKVYGVTSEGVAVFADVALRSQNIDPKKQPFTVKITGGTDGDVAGNVIKILHREYGSNVRVVGICDGTGVVENPDGLDMDELLRLVEHSLPLSDYDQSKVGANGVFHGVDNPEGIRARNSLHNRVKSDLFIPAGGRPNTINENNWHEYLDADGNPSCKLIVEGANLFITPEARQLLFDNAGVVIVKDSSANKCGVVCSSYEIISSMLLQTEEFMNVKQELVEDVVVKLRQLALVEAQLLFREYKKNPEAALPPVSERISRAIIRVHDAVLEKFDDVADEDKKVLYTLIEEHLPAKLKETALDRVHREVPLSYIKCIVASSLASKIVYREGLQFTESLPDSNLANLAVEYLKQEKKVQKLVKDVLASDLPNKADIEDLLLRGGVRAGVDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS61</accession>
    <name>A0A8K1CS61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS61"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF130">
        <property type="entry name" value="SERINE_THREONINE PROTEIN KINASES-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="474" mass="52379" checksum="10DB6FB955B886B4" modified="2022-08-03" version="1">MFALVEGQTLLGRDGRYRFLSRIASGTFAVLLRAWDSVTDSTVAIKCIQDPAFNAIGEREAALLRELNTRDAMGNVAVVRVLDYFVEQSHCCLVVELLGDPVLDVERWGSWRQARVPFLSEHEQEPQHKLYALLRRQRRLHDGNTAPVAVEPTPVAQVDPLPLHRIRQMAVELCAALAFLHDQGVIHADLKPENVLNASSDGASSAGLKSVKLVDFGNCIEQQQIALYYNALEEEGMQGFDIQTLAYRAPEIATGLVIGPAMDMWSLGCVLVECATGSPLFASYSEDSTSMPGTTADLLEQIQWTLTGGKALSTVCPSYRTARYTTKDMIKKDSQSPPLRVRLKQSRPRDVAEGEWHQFEDFIERLLTIDPTPRLAAREAFLHPFVQAMFPFQLIFAPSLSSFPPISTFPAVAEDSTATTTTTTASIKTKRKRTEGARTTAKTLRFETKIAGQRRVGLKAALKMIPSALKDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSN1</accession>
    <name>A0A8K1CSN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Mre11 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_007880</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSN1"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000019">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="18">
        <location>
            <begin position="302"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="508"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="606"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="662"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="688"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="749"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="817"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW68208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="881" mass="97794" checksum="D9A246E57F99B562" modified="2022-08-03" version="1">MATGGGIQTQNTLRVLLATDNHLGYAEKDPIRGDDSFRTFQEILQLARHERVDLLLLAGDLFHENKPTRKTLYQTMRLLRTHCMGDGAVQFQIVSDQSINFPNFGTVNYEDPNYNIHLPVFSIHGNHDDPSRDAGGADAQATSLAALDLLSAANLVNYFGKSEKVDAIEVFPVLMVKGSTKVAIYGLGNMRDERLHRMFAQRKVVFRRPAEAPESWFSIFVVHQNRDDRGRGTKNCLPESMIPDFIDFVVWGHEHECLIDVEESVKGDFFITQPGSSVATSLVEGEAKAKHVGVLEIHQQSFRLSTRELKTVRPFKMTDVILSEEESLDPNDPDVTGRLQEILEERVRELLIQVDEEERASGQKRPPELRQPLIRVRVEHSGFPVLVNQRFGGRFVGKVANPNDILLFYRRKKAQTSATDKKDGIMTGAEKKRALSLLTEPIRPTRLDTVTIEDLLTKQLHRPEQSLVFLPEAPLAIALEEYIVKNIPSALDDFVTQVLEDTQRDLVAKKDAKSKQEIASEVEKKKERVNAAHLVDEEEGRTPTASPLRSQPLSARSRLDSLDGSDEEFKSEDTRKTTKSSSARVTKATPATARSKRATKPAASVNEEEDSFGSDAMEEVATKKPAATTRKRTTPVKKAPTPRKAPARTATTKRKAQRDVFSDEEEEVDNDGDEDYEFKGDDDDESEAFGRGKGDGKARRQSPVAKPKGKTPPRKRLRRATSDNEDDDDTFSAGSKQATVGDGEINLCSSDSDATASTAISSAAKPARKRPTPQPKITDMFMKERPAPTASVVADEHDDVESDREFTQIATARRPAAESQFEVASQSQSQSQAMGGVKKRKLPLSMLSASQSTMATPKLKRDGDPASTASALRKGWGRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSR6</accession>
    <name>A0A8K1CSR6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSR6"/>
    <dbReference type="OrthoDB" id="70595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="635" mass="71423" checksum="36007A39AA6032EC" modified="2022-08-03" version="1">MADRVYHELLAVPTLEQLTALQLSDLAWKTREQVFIALFQEHASSSEVAEQLRSRSRDRRLERKTEKVENAERELIRKQEERFRSEFMQIVATEMARLGAPSMVTWQKLVFDKDCCVQAFRILLTKIKSSRRSSSSSSVAALRRSVASASTFTGQIDQLDPAVNDEGDQEQTSPTSSSSDRVLPSLPQRTQALARATRRVSKADMPEWNSDTSTKEGDTVASVSTPREREVMTMGEADTGITIQRTKRSMQDKSAVAALASKVKKNQMETLQVDIAALTSENMKLRDEIAHLEELVTTLQDESSSNQSRQDDPLGQELRIRHLQAQNVQLLRQLRLMQDAMQDREYAESTLLTALGHWREVVEAGRQEALSAGAATQAEKGGKPVQWMFAVPEKLLDELSRVEQQIYHAKKSMSTAYEAKLRVGSATASFLRDNNASSIRFTDVFQPGYGHLRLDRVKKLEASLAHTASRLFSIHEQLLNSFPAQVNGSSASPTQSPGISDALASIRSLTLEMGALGVVVPTLKTRAREVGQHPQQMTVAQVLKMLLATANGGLTGKERDKTLKSMLKQLQASEHAVETAKDMYQREAEYWKNAWQMQEQLLLTLMHRVRTVGDKKMQWRHSKKLDSTRTRIYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTL3</accession>
    <name>A0A8K1CTL3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTL3"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="302"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="367"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="470"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="631"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="664"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="697"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="730"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="862" mass="94330" checksum="3FCD506C3ABEA4EB" modified="2022-08-03" version="1">MPLASTAKELAFLTAARTGHLDQVRKLVGAGTDLFVTTEENESALHLAAAAGHADVVRYLLEADTDEKLVFMRNDHFQLPTEFAAIHRHVEILHEFARLSDGKTLLERALCNCAERGDIQPVELLLTLGVDANATEWGESVLWKAAMLGSVDIGSMLMHFGADVDWQMSDSGRTALHAAASAGEIAVLDLLLAHGATVDTRGVDGSTPLHAAADEGHVRIVQTLIEHGADVNAVDETQITALCAAARFGHADIVAFLLQHNADTSVVDKSHQTLLHHAALGRSLVVQMMEGYGLDVNAVDKDLMTPLHNACKAGHYGAVSWLLDHGADVTARAKSGETALHFGFWHSYIVKMLLAHGIERDVQDTKNGATALHLVCDDLVEAEDSARQLLEHGFDVNRRDMDGQTPLVRACFRGHYTVAMQLLQHGADPDASDGEGSTALFLAIGNNTPAGLVREFVARGADPHQLSRGFEYSLLHQACSHSNLGVVRVLLEFGVDATISDINYWTALHHAVDNSAERSAGIVEALLEYGVDPHERRIIADDPLRMATEVGNVEVVRVFLEYAPFLEKNERYFARALETACADNHMDVATLLLEHGTRASYRILCAACHSGNVELVQVLLVDVEPTQRSGFQKVALHTAASNNHPTAIQLLVANGVDINEQDQGGGTALQAAAKQSHTPCVRLLLEHGADPNHADRNGWTALMYACMKNELNTVEMLVTSGADVYYQSPEGTTPLHVAAMNHSLLVVSYLIKLGVNVQARERRGGFTPMMRCIQRFETTDMLKTQTAMELVRHGATYDLIDVIRHEWAPPMWVEAFAFLVQWWVNERNEGKTLTPVPEELLARDRESMEEYLIGQARKRAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTL6</accession>
    <name>A0A8K1CTL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTL6"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000016">
        <property type="entry name" value="Asparagine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003037">
        <property type="entry name" value="PRK03932.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="8">
        <location>
            <begin position="126"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="55647" checksum="5794D15BE5308DF1" modified="2022-08-03" version="1">MDAVLPPPPPTTTQTLFRRNRIRIKELFAAGLAMEGQTVTVKGWAKTLREAGAGAFAFLELNDGSCFTGLQIVITREDTEGFAAALESGGVGASFSVTGTVVKSPAKGQEIEVKATKVEMYGNIPDPGTYPMSKKRHTLEHLRENAHLRPRSNIHGAAMRLRNAMAFATHQFFQTRGFLYIHTPIITESDCEGAGEMFAVTTLLSQHPDGKLPVTAENKVDFKMDFFDRPSFLSVSGQLNVETHCCALSDVYTFGPTFRAENSNTSRHLAEFWMIEPEIAFADLNDNINLAEDYIKYCVQYALDNCKDDLDFFNKNIEKGLLERLTGTVAAPFERITYTDAVALLCEPQHLKAGKFEKKPEWGVDLGSEHERYLTEKVYKKPVVIYNYPKEFKSFYMRLNDDQKTVAACDVLVPYVGEIVGGSQREERLDILRDRLVESGANPEEYQWYLDLRKYGTIPHSGFGLGFERLVRYVTGIENIRDVIPFPRWPGNAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTN1</accession>
    <name>A0A8K1CTN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTN1"/>
    <dbReference type="OrthoDB" id="123721at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439:SF440">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="508" mass="57656" checksum="273EEC142FC1EB16" modified="2022-08-03" version="1">MACDEKEQWLKAVKAEFDAHSRNGTWTKVKRQTWMKVIKTKWVFAKKFNEHGDILRWKARLVALGFLQLFGVDFFETYAAVASMGSIRIFLSVCCAAGYILEQLDVDTAFLNADLKEDVYIEPPEGLKVDGDRVLKLNKALYGLKQAGNAWFKTIHGALIDLGFKPCGSDTCIYVGRAGGDTTYICLYVDDMVVGGRTQTRVDEVKKLIAARFRIKELGPVKHLLGMEIVYDRVKRYLSINQAHYVKTLVERFNQQSCRDVTNPCEQSLKLSKADGPRDDQQKAEMSKRPYRSLIGCLQYVAQCTRPDIAFAVTHLSRFMENPGPRHWTAAIRVLRYLKSTRDYGISYGGDHEENTPVVFCDADWGTSVDDRRSVSGLVIMMNGGPIVFKAKYQSTVALSSSEAEYLALSLCGQEVMWVRTMLHDLGINIKKPIQVWEDNQGAIALAHNAGYHARTKHIDIRHHYVRDLVADSVIKLSYVETQRQLADILTKSLGTKRFEFLRELMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTS6</accession>
    <name>A0A8K1CTS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTS6"/>
    <dbReference type="OrthoDB" id="5925at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="366"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="588" mass="64933" checksum="A4D264B246E4E1FA" modified="2022-08-03" version="1">MRATVRSWRLVRAAPKQSTRAAASVLNGAASASHNGPTSAVEVMLKTNATGAVATQAVETMHSSSSSMSFAVASAIAAAAVAVSGQDAQAEEAPKEDEKRLEYSEVVEILREQVSEFRTTLKSTESRIPKAYPIQKIAISRAHAPNGVSTIRIEFVCPPFVDQEAILGRFLLKLQEKTSSQRQPVEVVGVQSGDVDSKSIVESYDLPSVSYLYADGHGSFQFVRDASMQRNKGAKFVFYKDEYLTPGEVDAVVEAYKELYSYPNVHAFFNHEHNQMRRRMLEDRGRKGPNLTVPSPSKDEAIQQLQRLGIDVFEPADSESGLNWDSLAGYDDVKLEIEDTIVLALQNPELYDRIARKTRCRYESNRPRAVLFEGPPGTGKTLSARIIAQQAGIPMIHIPIESVVSKWYGDSEKKMSAIFDACEKFDGAIIFIDEIDALAGDRAHGSMHEASRRILSVLLQKVEGFASAKKTTVICATNRKQDLDSALISRFDLCIRYELPNESTRHAVFARYAKQLNSNELAQLASVASGLSCRDIKEICEYAERKWASKVLKKEVTDDLPPLQAYIDATKVHIVGISNEGSQNDVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV83</accession>
    <name>A0A8K1CV83_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV83"/>
    <dbReference type="OrthoDB" id="61473at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="220"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="39439" checksum="789FD6F1CAF2DEEF" modified="2022-08-03" version="1">MKRTNSKGQRTEDIIHPEEDIPREQFFKSVPLMKLRVDGTSHATSLLSSAEHKVREQLLIASEKGKKHAVYLLLHQGVQQSRCRGMRGFSPLHHAATRGHLEVLQLLLNFGWGANIRNDFQETPLHLACYNGHTAIVEFLLDKGGDINALTSDGETPLFYAARKNHYRIVRILIRRECNLAVRNRFGDVAEDEATTEKTQVEFDVGKEDASRLYHGSGATSGEHAITQKLREQVLAYLDLKSLCRVAQVCYRWHRASDSPSLWRNLGISRWELSLQTTVGIGAISQMSMMSLGSSLQLNLTSTSGGSGTRRPSSCDQVSSRVLFESKSARRASGGHAGIILGVGRRPQTARTLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVT8</accession>
    <name>A0A8K1CVT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamideisomerase</fullName>
            <ecNumber evidence="3">5.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVT8"/>
    <dbReference type="OrthoDB" id="446074at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000110">
        <property type="entry name" value="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="257" mass="28605" checksum="3D310225DF383930" modified="2022-08-03" version="1">MRFRPCIDIHAGDVKQIVGSTLTDGQEDPVTNFVATMSAGAFARMYKEDNVPGGHVIMLGASEENKRAALEALREYPNGLQIGGGITDENCQFYIENGASHVIVTSYVFRDGQIDYERLEKLKSLVGKDHLVLDLSCRKKADDGKFYVMTDRWQKFTTTAIDEALFHKLSAYCDEFLVHAVDVEGKRCGIQQELLELIAQWSPIPVTYAGGARSLEDLEFVERIGNGKVDLSIGSALDIFGGDIPYKDVVTWHQQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CX03</accession>
    <name>A0A8K1CX03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_001944</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CX03"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="116"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="235"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="328"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="429"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW69788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="523" mass="58352" checksum="BF8EDB9A08E6D821" modified="2022-08-03" version="1">MLARRARRITTDPKHHSSFLLGLTPPLAFFLHTAHAMSSPKATLVRRNSRLTVDQMLRDAFDRVDVNGDGKVDALDIQKGLRTAGARLSTDEVSALMQKLDPHNRGQITFDDFHAIHEAFISKTFKEFDREKKGYLDDASLQEAMQRLGVQVTLAEAHSMIEELHPADARRVQENDFKYLYLLLRAKMYSPSGFEHLLWDPDVRHLSKHWWKASVEVGEGGLRAPLPQKKEAKSVSPTIKFFGGALSGVIEALILTPLDVTKTRLQLDKTGQYKGFVDAGKQLFRSEGPKGLYKGFTPWTIHVVTKNGTRFYFNAIYRRMLADKNGQVSGANEFIAGALAGATEAVLIVTPFEVIKTRLQGQNVIKGQELKYKGTIHTALTIMRNEGPFALWKGVAPTIGRQGLNQACSFWSNNAIKKHVWRLEDGETLPAWKSGLTGMLGAIPGPCLNCPLDVVKTRLMAQEAGKGQVAKYQSTLHALRVIPQEEGFAALYKGLIPRLTRLCPSYGIQWLVMDQVTAYFSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9V8</accession>
    <name>A0A8K1F9V8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010517</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9V8"/>
    <dbReference type="OrthoDB" id="10051896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436590" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="48"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="28300" checksum="028C4435E42E6CC0" modified="2022-08-03" version="1">MKIAIATAGALLAATVAAEPLTYTEYLEKTQMAALFANETESAIKPLILGGSVVPVGSKLWTTGLRQTQTGSAFCGGTLITPKHVLTAAHCYGYAKYVAVGSHYLSGSSDGQRIAVLKETRHPSFSSSSLTYDFNIIELASTTTVAPISLKTAEPSVGTTANVAGWGTTSSGGSQPRELRSVDVPIVSDSSCAAVLDITPSTMICAGGQANKDSCQGDSGGPLTVKSGSSDVLVGVVSWGNGCGLAGYPGVYAQVSVAKSWIDSTLKSAGYSATWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAR4</accession>
    <name>A0A8K1FAR4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pseudouridine synthase I TruA alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAR4"/>
    <dbReference type="OrthoDB" id="25767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF5">
        <property type="entry name" value="TRNA PSEUDOURIDINE(38_39) SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="273"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="483"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="59312" checksum="3AB474153FADA969" modified="2022-08-03" version="1">MDRTMTPSDGLNDAALGATALALNATEATGEKAPVLDTNVDKAKLLAILEELRNSVGTKAVDDAVVKVLSDPSASSLLPGQRSNKRQKKGKKKEKVKREFQMDNYAQRKVAIKFFYIGEKYDGFARQGHTDETVERYMFNALVQTKMIKDIDSSEYTRCGRTDKGVSAFGQVISLKVRSNLPVNGKLLDHESIDEVPPGVKFRVQMPKGDIRNVTEVDYTVAINRALPDDIRVYSVVAAPSSTFSARFDCDARMYRYFFVRKSLDIEKMRLGAAKLIGEHDYRNFCRIDTSKHTFTRAIRSFEILKCEENVTPSESEQIYRFEIFGKAFLWHQVRCMVQVLFLIGEGKEEPEIVDALLDIEANPRKPQYEMASDAPLCLQDCLFDGVNFDHTPLAMYHVYDHLSSLWERSAIKTAMLRSNLDMMAPFTVNPKRVIEELDHYAPKLEELMKERGYMEAESVLWTDVRPLLPLSARTKYFPLLTRNTGDSVQEKKDKMSERKRRRQGPDDEDDEPDAQRHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBP8</accession>
    <name>A0A8K1FBP8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="206118at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="370"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1298" mass="148004" checksum="B345C42FF13F6ABE" modified="2022-08-03" version="1">MVGSYVSDTLLAVQDAEFQVQSAIAVREQYKAKLQQLLDVLVPSGLKISSPVGLKASKTKTKATLRPTEGRDAIAERLRTRATLPQGKEMHVLGDWLLLLRAASVNVVESIQEWRHVVHQNRPAPYESTEVPSNYLLHMCNDVDFLNQCPDLVEWLGFRLVRNPFIIRDGLDPDVDNTVNTQVSTIALMSPQYRIKSTKQSQTSAPPAALVKPLISILPDDDVVDGTRIAYAQSILQQEEALYGRRELFINVTKYVEHRPTDAEKPILAGDTAKMATVYDEIAVVSRRLRVEKVKLSKEERNLDKVIQLRHGLAQQISLTTKHREQDMVKDHRVWRMQEQCRQETLRMVEAWDRALKQREDELRLAVGHCQEIVSKREKELQRLEQQQTEARQNRRDEKQQKVLKEAEKRRNLRQKTVARNQSIKVIRRRRRSESSLTETSNPLDIIEPLQSPGDDYAVDIVHPPASPVSDRRLELDAKRIENLERRDVLRLHRKRTQEEEDAEMERRRRENAQMWMEDARAKALERRWKRRIILKAEKERQQRIASIPLFSTMQELGGNNRKKFRVSVYPYRAKGYALDGLRIAAYDPATSNTFSLIMSQREYGSLGYGRTLEGFTAFCQWLCLIYEKRKRQFRLIWSGAPCPPPLRIKEYDQALVCVHKEGIRVYSSVYCLVAAYIRTSDPGVVRFVVFGGISGQEPSTWVEEFAVTASELVPTASIVNRTDPNGYQYAIWLHDAFQTHPFDESRPGTAISTVEHEAKRVRVFSGELMVEGKRHRAHIYDVSETECVLALSQSKETRAQAAETVLLKHDVNPYGVRLPHSAFGDLLSCLQLELDGESQCKVTILPRWRDRLAKFVRVLRMARFGCKIDGVFHLVTLVLVQQKTEFRAHLLLEMTRVGNHMTRHSLSIRLSEFLRCPDGFWRATKSNDSSHEDLECVECLDNRQALDAELHAHNDVTTLHESEYDVPEVCETCPSIQAHRIERVKELVTTATLSDEALQYLYYASCPSCDTLPQPIAIAVSSVVQGTNDLVENVLSHYFSCFNVGQLPTIAADVRHTLDHSRIIVLYDVPIGAMVDSALAFLEHLHWSLYPEEYEKMPLHVVMCIDDIVQRAIERDSHASVTTDVALHDGMRGLLDAITTIGSVHSSQDSDELLNFDAYLVSEALLVEATRVVMYPEHAWRMPGETIGASSWGTACEYLIKPQIFCQELQSRVLQSFGVTNLAILRGYEGHPKWPAQYEDLRPQFHALLNVMLHILHVHSVIEHGGGLLHQLAEASVQENSVTRLPSNVSIVRIAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC09</accession>
    <name>A0A8K1FC09_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC09"/>
    <dbReference type="OrthoDB" id="67991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="40393" checksum="AB8A748FC06EC473" modified="2022-08-03" version="1">MKRLWVQVIDDHGEEVTTAKQICSESLVRIVDLRNAMRPHFPNVLSTVDNFELKMYTRSENGGKEGPLDATSALDGLGQDEENALLVEAPPHKERPRYQYLFRSIGPKLRKPHLVREKLISRIHASLYESDNRFVFLSAPPQSGKLTALFLFERKYPEVDCVGISAANPIFHPICALERYCGIDLNTKSTTLNDGKKHVVMINQAEQKYSDSQFWKALITEAPTWLPSNIRFIISGRNTAECPIELSSLPTFGPKDFTLSDKEAKELLELPITGLPRRLRHNRLMKLVIRECNGLVGALTSSASGMDYRFLNEPTPTESELTAYYFSNEFLKRVPDCFGENAHHLLLRARRFVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCW9</accession>
    <name>A0A8K1FCW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCW9"/>
    <dbReference type="OrthoDB" id="119067at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43021:SF2">
        <property type="entry name" value="CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43021">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478543" description="Cation/H+ exchanger transmembrane domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="67"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="293"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="913"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="923"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1025" mass="112304" checksum="FD0E30E68A4C4262" modified="2022-08-03" version="1">MQRRLLCALAGLLAMGLPRVVAFEDDDDHQHATRRLSTPFADSESAKDALVYGLAFIMVLIAAHPLGVLFPKYLKLPLITGYLIVGIIAGPFVTELLPTKLVDMLSSIVSALALSFISFQAGQEIYLPELKPQIKGILQLLLVLYVTTMVILTGVLMLGNNPFFFDKFESSCQLAIALMFGSIAVLGSPATVMAIKIELNSVGRFTNLMLGATMTAEFVVLVSFSVSRVVSSIYCAKLDISVANLIFTLAIVLANLVIGAILALVIIAIFLIPGGPDHDEHSAALLVHQDSVSHQGSTPTTAAQYLQRRNSRSRVSLRKELESITEEGEAHYESGATPMANQRRGDLESGISRQQSNSSMSSADNMPHPHNAYVEVDLEETAKLSFREHCMEWIGSLFFKGFLWLLMGHAFYIGTMTISEATIAGYGHSWDVKFEPLLVLMTASCLAGHYSSIRHDMHIILDTAAPYIFLPFFVMTGAALKLDQVVDAIPLMSLYVVLRFVSIFIACYVGGRFVLKLSPEQYNNLWLTMTPQAGVALGLANEVKGLSTEPWAAEFASTIVAAVVVNQIIGPVLCAIGLSRAGESLASRMAAKEGEECAAVNGGVDSDGKAKQMVQDSVMVQGNGDPRPLLPFYKVQNAVVIGEDEVAFEVALELSLYGAHVNVPLLDEELAEKWHQINDAILARTANGDLIKYKNKLQDSKHGTNEHIEGLTALTDVVIFTGEPERTIEHVKTMQATMGRQNCPRLIAVIPDCTQAKTLKDMGVLLIQPSIALANILTRMALLDLHLAQQLSNEISTTSNFSTASYFLRHDADRDSEHSISEMRLNTRRLALGRSVVNHHNVNYEKVAEALMAANQPLPPPPPRVSMFGTTAPGYDPFAKRQEGISAYEYYAVDDDLLPDDDGQVFEEQFMSPRDAGQQPLFQRSRSQRSSQNSQTRAVRRSRSRSRSGSAYVRTNSSHTPNYLPRLQLTRTAFAVASSIRMIGEPTSCSCIILHEGQLGHAAPVEELPIRCHETKEKWALCWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDC5</accession>
    <name>A0A8K1FDC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nonsense-mediated mRNA decay factor SMG8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDC5"/>
    <dbReference type="OrthoDB" id="63589at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019354">
        <property type="entry name" value="SMG8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13091">
        <property type="entry name" value="AMPLIFIED IN BREAST CANCER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13091:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="51423" checksum="64CA53AC84390B2C" modified="2022-08-03" version="1">MPSGRRPTPRHHASPPLPPPTVPPLEDLCNEPVRIYPAERTRGASPASAAAKSPGKDDTADGKLLLQSLLAVSKPVAIVGFLGAQTSTSQGLYTFVNRVIGRVAFMDENADDSALGKTSPLLASIQLFYDESRAIAYLVGVTKPEGDVLKRVLLGDGHTDPREAATATLTAYQREKLKMELLLYSCCNLVFHYNESGRVTTNILKQIRQLAIEKQQVLAQLATGSSKNTKQREKGSGVVNVFAPGRCVPLVLFVVPAPEELFQVTSKQVTSMKSRSSTVAFCKAQEATLCTLFRSLRGGLVGSLRSRDAVTPTNLSKERRLFHVDPSHCVVVVSKKASSDEGRVERRFESVLDQLPWDLSTMEQPWDLDALLKPLEEDDIGFPNAIQQMNRFVESVFHASSSSTNDRSNKEINAKVELLTLSQWLKAFQSLVKTMHRVEAKKKQEMDIGNDRENTRLAFDHIDLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDN0</accession>
    <name>A0A8K1FDN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDN0"/>
    <dbReference type="OrthoDB" id="93327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF2">
        <property type="entry name" value="C-TERMINAL OF ROC (COR) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="58703" checksum="653F890BDF17DC00" modified="2022-08-03" version="1">MDIVAVCVKHWADEQQHRKRALTEIPFEILIRGGETIETYLKEVRESSEEDLVLRRKVCIVGSSRAGKTSLVKSITSMSSTLVADDDHTISVDLFHLSFTEEIEDKDSRAGKKYHDVSFWDFAGQDEYHVAHSLFFSRRMLYLLCVDVTAFNNEVEKSRSHKDQDNEDAAEAVIDAFVRERVWRWFRMIFTRQPDAEFVLIATEADGVGNNGEERLQELAVELFGVLDDFKSSFMDEMEKEIEILRKRTSSETDAETQQVSKSRISELEKLLMQLDESLPSSWTPLNVCDQESIQHARTVIERVVVDSGRSFLMPKKYSRVLEAIQELRKEKPNQTTKKRIKQIIVQLPTLRKQLMQSVDELAEKECDTILETLHDLGDVLWYARDGLNVLGETVILSATLLIEFIRQIICHNPSESGKSMDNQLVEELQQHGKVAHRLVESFSLWKRLTPKQMLQFKLLLQHFRLAFPAGATDMTAESDLIVPAYWHVRQNQVDLEALEALSDKITQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDS7</accession>
    <name>A0A8K1FDS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDS7"/>
    <dbReference type="OrthoDB" id="6268344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039872">
        <property type="entry name" value="KIAA0513"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13663">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 6430548M08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13663:SF2">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 6430548M08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCH" evidence="3">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="743" mass="83971" checksum="F39592C5040B258A" modified="2022-08-03" version="1">MERTFGMDDNKLENHWRRTFCQMPFPAIYEHAENGKRSLHRLVEFFRRKAEAERSASEELRSVLHTPMDSSTTAHLEDLEEHGTSIRRALAEVKNYVDASCHQHLLLARVLEEQVAEPLVSLQDASEMYIRTLKDEIRNVNDEYMQALNTHSQAAARLQRASDDLTEALERQHIALHGIGVPTFELQRLATRVAKCEEEKAQALFAKAQAKTHLYKRIVSRDEMAMAVSVAYQRAEEERLDQLHSCMQRFLHIEKERAKATDKMLKTLEQQIEHMNRSEDIQMLIHNHRNADNMHFQGKALALLDWHWGKAIAERERHHHHHRHHDKPHHERVGTDNGHDSTVHTAPAGQQDGLLADPIEIPPLDGHVNDFGNEPQRSPHGALADTPMGQALHKLFAEDSRPSSPVNASMVAPLPRSESDTSSDASSVSEEDSPPPSAAATAESGDVDVELQQVAQLLEEQVALSESTESPALPSPTTKAPSLPALEEIVQSACETHKGRALFVRCLNRQRSLETRLRDRQAFDALNSCFNIFLDRCIRDDDVKAAKTAMILAETFYVARDSENESEDSPSEASHERRERGGSWGFAPRHMGRGASRIYCQVEVKKHAIWKSPSFWEKALLHAIGEELQKTPQPCSWEDLPSGITRTASQSSGLSEQQHRSSPHSNGPVVIPTREEAVSRVHNIVFGQLGSFTLSMLEFEVPFTQIESFVETMCDAHELTEDQRFLLRKNLQEICVALQYKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP6</accession>
    <name>A0A8K1FEP6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP6"/>
    <dbReference type="OrthoDB" id="2357150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00835">
        <property type="entry name" value="RanBD_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF183">
        <property type="entry name" value="RANBD1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="153"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="31444" checksum="F2691CF8A9CF6220" modified="2022-08-03" version="1">MATNLEHEKPESDVQRTAKKVKLDDDAVSVDSNTVVETKAESVDSTAESEQQKGSDDDASVETADEEDASTTTEESKPASSGFASFSSSSGFASFQNTASSGFAAFAQTATSTSTGFGAFAQTASSSSTGFGATASSSADFEGFGKTFEKKTETTGVAALADAELANGEEDETILVEKRAKLFKFVDSDYSEVGVGPFRVLKPKDAQDDDAAKASARMVMRRESHPHGPGTKLLLNARLSACLSCVKKAEKALMLVIAETDEADKIKPTTFLLRFASQEDLLALQDAVKALLPAHATTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFF3</accession>
    <name>A0A8K1FFF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFF3"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="98"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="100"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="36202" checksum="D22A49766A55A7A9" modified="2022-08-03" version="1">MTPLLTPSSPATSTDSRADDVAVLPSPSKLPGLHFAITHRRADLRLPSLASQTGGALHLAMPQCETPHYLPGVPTCPETSPTDKKLSDMKSSLDAKKRKKGTRRGTLNADAKNVLKAWMFSPEHFAHPYPSEEEKEELASEAGIEVKQLSNWFTNARKRLWQPVLRQSGVEVKNFLSTGRGGPRGNKLDVPPNFQHLIAQKDTPPSSPGRSSEPTTMNAASHIKRSWSEMQSSPAPSSSTNMDEVAPKKKKSAQRKCKDNITDEPTRSLTHTATQLSHELRLALNNNTYPHTTSPSRVMTVASNMATFQELEILAAASLIGLHQQYQPVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFR1</accession>
    <name>A0A8K1FFR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFR1"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="19"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="35587" checksum="68DE5F55AB1CE843" modified="2022-08-03" version="1">MTDAVPQTFRGYVYENFGDALQEVKLRSDLKQAPLAPTLVRVKVHSTAMNPADYKMVEFGAAMSPTQPTPETPFRLGFDVAGTVVEVGSAVEDVIPGDAVFGMSYVSFGPNGTFAEYVDVEATHLAPKPSNMTFNEAAGVPGVGLTSYQALTTHGNVKIGQSVLILGGTTGTGLFGIQIAKALGASFVAATVSSRNIEFMQGFGVDRLIDYTREKWWDVLEPHSIDLIYDCGVEPTAWVDGAQRVLKKDTGILVTIGHSEEPVPSPIGASFKRMRVASVKQDLISLTKLIEAGKLVTPIDSVIPFEKLHDALKKQKSNSARGKIVIEVISSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFV2</accession>
    <name>A0A8K1FFV2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFV2"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11559">
        <property type="entry name" value="W2_eIF4G1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="295"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="51841" checksum="057CA98AB742CE96" modified="2022-08-03" version="1">MARRGKKMNLGEFLGDQTAAYIPEAALPTGPRARDEFEDSRGGRGGYGDRRGGFDREASRSEQSDQWRGDRGGFGSRDGGDRFGGRDGDRFGSRDGGDRFGSRGGSRFEESGDNWRSGSSRDMGSRYDRPARGDFRDREPEERPAHMRLNLQRRGESSSASDEPSRGGASDDKWSSAFGSRGGSSGRFGDRGDRFGDRDGGRFGDRGDRFGGRDGDRFSRDRFDDRRGGRFDDRREESVSSSFNNLRVNDDKPSQAAPADEELDKKARAQKLREERKKKAEEERLAAEEAKRKAAEEKKAAEEAAAQKAEGDRAIIAEVLASGKTGEDLAKVAKTVFAKSGRPSGAVIFEAVTKQAESVAKASANWIAPQQYGELLKFAMADAEKDDQVKALYALQVFLNTHDFPKGVMEKCFMALYTLDIIDEAAFFEYKYDVDSDVPGRMKAIVQTSNWLTWLETPEEESEEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGH3</accession>
    <name>A0A8K1FGH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA nucleotidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010714</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGH3"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000019">
        <property type="entry name" value="tRNA nucleotidyltransferase cca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="34"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="7">
        <location>
            <begin position="199"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="59835" checksum="E0AFDD590064A91B" modified="2022-08-03" version="1">MSSEHSAITLTPAESKLFDFLLYIRHLYAPTTQLRVAGGWVRDKLRGAESEDIDIVLDNIYGKQFANHITTFQRQRKLPMSSVGVVKANSDKSKHLEVAQVKINDLMVDFVHLRSEAYTDDSRIPEATFAAPTEDASRRDITINALFYNIHTQQVEDFTGQGLDDLANRVIRTPLAPVQTFLDDPLRVLRVIRFACEFGFSLDTEILDAMHTHDSIRDAMKRKVSRERIGIEVRKMLSGSDPSRAVGLLADFELLEIVFDHEQSEQPPSTPTPLRDTIVWTPEQMEQSHKHVQYLQQTRQAIDRHQISYVESTAAMLAPFFLPSGRVQELSTGLESFVSTSSTWMEKVDDETIIEISMQFLQQREQVLREFPKEELIELLKISVKWPKPVAKRVALTLEAILAFPSTISTQDGVQNHIQLFLWSRRYHDVLAIAIPTLLTNLEPEEDREKLVMALHALTQRFIQQSESDKRRKLDGKVVRDSLGGQAGPAISHALELLSVWELVHPEGSRAQELEFLDRLRLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGM1</accession>
    <name>A0A8K1FGM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGM1"/>
    <dbReference type="OrthoDB" id="165256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="860"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="960" mass="110031" checksum="68B043E1DE34B092" modified="2022-08-03" version="1">MIATSSRAFNAWRLLLVPMSSSSSSPRKRPPSPVKLTPLEKKARDRERLHEQAARRKQRIAALFDGTRELLLAQSESAQWHEQERLEEELVLRRLERDLIDPQKLHPSVAGYRFSPSSAGCDATRTSPVFQGHAFAHCPSSEQVLRPPTHCHPSFMGYTITHHTDTTQLSPVFFRVGFQKIPLEEISLEDEESDASSDEGEGDEARTQEQFLSRMDARTRHPPTRAKLTPTEQKQLDELLVSRLEDDTPCAICENRRVLGCPGCFSFDWALYRKIQADKSTQRLKTPKTHTQEAYEFEERHKGLQRRLMGFEKAEERDERVKTPSKDTKWAYYAHALADDHAIRKHRILNNNVVILHIKSLPVGNLITLQVDVQASIASVYELYRSNHENPNRRIHLLLPTTTGLFYLDDALEDATDTRTGLVNGAFLLQDFHLTSHQPSSPLRTRAPLEPSTTITEYMLFSVALLSDESTPLLVRQYLQQNFHLADDFHQRLAIERATVRLPHAVALDACQQRLIPHVHRMKAFAQSTQRLDHLERERERERVLWIAYQEKKRAKLEFKKRQQQLGRAGRGASRIVMRAVAYLDYVCESTSNPRRARVAEERLGKLWQCFQRFEEWKICKSGRLLDAESTEDTLKLLQRHQDVTVAAFDTVMKRGPGSGPLLYPVLCVGGSTTRRLAVKIGNRFGLSEADNYEYGLVLDVEQDFSGGSTSRVATLKRDFTKKQLLAQQEDDQRQRDLEASWRCADLEWRIKNGSTPPPMLFTATDLLRPPFYQFPWHSMAQAYQFTLQSVAFQVAKLDEFNALARVLQHEDAILSKAQIEKWGQDVDRFHDELVAQAESTSPLLKTSVLLAATRRVLQKKGLALLKKRLKQRKQRLREREAELERLRLLQEENDRPKRSPIELMKDAFVKEHAPKLLAVLELTPAEKLLLKAEQLVGKVATKAASAAKAAKKEYHVRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGQ0</accession>
    <name>A0A8K1FGQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007082</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGQ0"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478823" description="AAA+ ATPase domain-containing protein" evidence="12">
        <location>
            <begin position="26"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="210"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="47286" checksum="D6A6ACB2E25CFCF1" modified="2022-08-03" version="1">MRVPTPRRVLLAIGVLVVLRKGVQGVREALLSWLQGSGDSSAVVAAAAASPPWRLFSAFLRDLRDDKVSKVLLASNFVLVQGKEGLDTYKVLVPPRTENTYILDTLVRAGVEFGTLQPPATRKIFPLVMALIPFIYLGLTYRMLRGLFGAESGGVGKDGSQKKGLLRRASGSNRISFDDVAGIDGARQELEEVVDFLRNPARYEAIGAKVPKGVLLCGPSGTGKTLLARAVASEAGVAFLFCSASDFVEMLVGRGAARVRDLFTQASQHPQCIIFIDEIDALAKARGGLNSNDEREQTLNQLLTEMDGFEGNVNGVIVIAATNRPEVLDPALCRPGRFDRHVYVGLPDARGREAILRVHTKNVRLDDDVDLTVISEECGHLGQQSGAQLASLVNEAALLAVRHGDTTVKHCHFELAMNRAYEAHCKNLTGAFDFEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH28</accession>
    <name>A0A8K1FH28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH28"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21662" checksum="624048E17637A02F" modified="2022-08-03" version="1">MSSPIKLTYLDVTGRAEITRLVFAASGIAFEDKRIGYPDLPALKHTLPLGQVPIIEMGGKTYPQSMAIARYAARIAGLYPTDDLEALNVEVVLETLVEVAAGFGEIIWGTPEDAKAAKIKVWTDDKLPKVFSLIESSIKGKFLLGDKLSVADLRLFDLFANSILLAIPDYKLDAYPKVAAVIENVKAVPNVAAYLAKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH35</accession>
    <name>A0A8K1FH35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH35"/>
    <dbReference type="OrthoDB" id="286233at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="34074" checksum="48E049CBE533B7DB" modified="2022-08-03" version="1">MTEYTQSPIFMISCGQLDHDLVTASLSVVAPPLVSWTEQDASSFFLTEIDAKVVADQWTVARAIARGSHHLYAQDEFQRAISAFGEALPLAEAANDKALLSLLHHHMGVAFKEEGKEKWALLMQKKSLELAQECHDLRLQGRALKALGVLFLDRRDAEKALDCQQQALQIATDTKDKELEARVYANLGNLGSAQLQMAHAILCHQRDLTASQELDSAVGQARAHRNLALVYAKLKRDAGTKARQLDHELNAARIIATSAFETDMRRHSDDSVGNIYVQITKHDSRMAEMVASSLQDILSEKTERSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHH5</accession>
    <name>A0A8K1FHH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nuclear-export cofactor Arc1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHH5"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042450">
        <property type="entry name" value="EEF1E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44490">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44490:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear-export cofactor Arc1-like N-terminal" evidence="1">
        <location>
            <begin position="92"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="19563" checksum="6EE910ACA39BA10C" modified="2022-08-03" version="1">MSLSLDKSPQAECLRFLARFCGVSTSSAASGPIRVRVAKNNELYQVNTIAKFFARQADREAELCGQNAIEKAEISMWLDFALGITRCPPAVAPAHWKVLESTLQQKTFFAGNRATLADAAVFWVVYDAVKGFSAKQRTEYANLTRWFDQIQHTVGVRGFRDLDVVALAPKQYALTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHJ6</accession>
    <name>A0A8K1FHJ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHJ6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="211" mass="23738" checksum="7397B33A4F7ECCBE" modified="2022-08-03" version="1">MYNQVDAVLSAHVSPHKQSRDTRLVFDSNVGLTMQIVESRVLPFSFKATADALWTVSVCHEYQTVCRETKKVDIHTATSDMMSKSFEGMLVVPQKSAEVHVKIALQRFNEPNRVILVHHILNDPKNIAGKPVCGAMMRHQSWTVLEQGPHDSTLMRVYHTATPDVYGPTSEVQSTLYTLTNFVLLVVQAHLDLDLRQLEDLLLCSDNALNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW3</accession>
    <name>A0A8K1FHW3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="24853" checksum="17B6423E4A072CDA" modified="2022-08-03" version="1">MCSTLVGIYFAYDDIMNICVFKYGLVDGQREMTPTSPTVLSFYNTYYRYTYGDQTNDYDALYFIDKPLVKITVYGMLFSVSAFLLRLVLAVVYKSYKGVLVKDVGAIWRTYQRNSAEVFMNTPVRANALIRSQQILSYRFGKAVFIRPFVYLEQNFYITRGKFRARPAIPFLTNEDAEVGADVDTKSYMLQGVFRDENSSKLQRAVSGRDVQIPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIA1</accession>
    <name>A0A8K1FIA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIA1"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000057">
        <property type="entry name" value="6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF49">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="5">
        <location>
            <begin position="60"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="514" mass="58197" checksum="79D1F34ABA1DFCF7" modified="2022-08-03" version="1">MSTDVDSISSLERRSSSDSDSARPPRAPSSTQSSPERTTAKSSNLAQHRSLSERRLFTPTADKLLLVMVGLPARGKSFIAKKLAKFISWKGNKCDVFNVGQLRRSRCPGTQDHTFFDPNNTRAREERELLARQSLQQVLDWFLGDGVNKGGEIAIFDATNSTKARRRVLLETFADFGKKHKFSIHVVFIESICTNEAVIHANMMQKVSSSPDYRNMSEEQAIADLKQRMKNYEAAYEALDDDEGISYIKLFDLQSRVHAKGIYGKVAKSVLPYMMSFHIVHRPIWLVRAGHCTEVRKDFQSISKDPCVASRSARLSQLGHAYARRLGQFVKDRSAYFSEQLRVEQETTGDYEENENNECPCLILTSTLPRAIETAQYLPEERRSQMASLNPLDKGECYGLSMDEMRQQMPEAYYAYMKNPWKTRFPGGESYYDLMLRVESVLIDIEQHTGPVAVVSHISTLQVLYSYFLGVPIENCSDLEIPFHSVLELVPNQDGWTTTVFNLRSDSSMASPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIE1</accession>
    <name>A0A8K1FIE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar protein sorting-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009057</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="453"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="6">
        <location>
            <begin position="2635"/>
            <end position="2951"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="6">
        <location>
            <begin position="3077"/>
            <end position="3307"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="7">
        <location>
            <begin position="3914"/>
            <end position="3998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="402"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="483"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1055"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1348"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1633"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1879"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2076"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2253"/>
            <end position="2280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1084"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1095"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1117"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1356"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1653"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1880"/>
            <end position="1889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2107"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2269"/>
            <end position="2280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4121" mass="457723" checksum="24F84E6135623FEB" modified="2022-08-03" version="1">[encoded data, 4121 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJA1</accession>
    <name>A0A8K1FJA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012768</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJA1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="255" mass="28943" checksum="7F413B15E1E8AA85" modified="2022-08-03" version="1">MLANRYRVQRTVGQALYGDVWLCEDTKCENELVAVKQVSLGRAKRALATYKHMDNPFDERRIAVHLMELDSHDNILQVRHEFLENGSWCMVMEYCEGGDLLSRIQDLPENRLDESLALHYFRQVVRGVHFLHDSGVAHRDLSLENVLLKNGVCKICDFGLSTEANRTCSESVGKGYYMAPEVLSGEAYDPLAADMWTLGVMLFIMLTGSPLVPCASREEKAFLALETFGVEKILELRQLAPVIDFDKSIQVENRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJQ5</accession>
    <name>A0A8K1FJQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJQ5"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF77">
        <property type="entry name" value="LD25952P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="110"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="256"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="46534" checksum="7F8EBD73A38706B4" modified="2022-08-03" version="1">MPTLSSSVGRPHGASTPHQYAAAAAASAPFLGSLASQASAVEHARSRFLSSIHVSTASSPPSSIGDLDEDVAPSPVLRRGGTPNPFQLHTQHSDHHSHQQPHTCDACGDLEAEFAAAVVFVETYQGPHRILRNENSGPKKEFYALYQQASVGPCPPLPLPEGQSKLELARWEKWRSLGQMTRQEAMKRYTTVLDNLVDDWRRSAGLKNGNDAQSASYVSTASSAGSVTSSLSPFPRPQVKKSTSMFERLPRIYDEFGELQERVEEEARKREELEAQILAFTQDNRLLFSRELRQIDQMRANLTTLVQSLEEDVALHYNELQQLIQQRQDLQELVDRSVTLAVERRLRRVYDIVKGWIANKAVRGVLFVLFVLRLWNFLRQRRLPQFLARFLIRLIATASSLEGGNEARRAVITSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK36</accession>
    <name>A0A8K1FK36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_012539</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK36"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="18">
        <location>
            <begin position="110"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW61348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" mass="59528" checksum="56C26697386C989C" modified="2022-08-03" version="1">MQHSQSEVTLGTTSGSWADLKDGLKKRSNTAQNLIFYVEEQKRLYQELPFMALPGMRRQSIQRERSFSNLKSRSSWGSFTNLVQRGEDQPLLGDADEFPEPGYTWPLLLSCCVALMSAFQFGYNTGVTGALTPELVFPGHTELEWAICVSIFAVGGPIGSLTAGGLSTRLGRKKALLVDSFLYIIAGLLMAFAPNIYVLIAGRFLVGYASGTVSVVVPLYLGELAPPNLRGALGTGYQFGVVTGILAAALLAFGFNGPSEGIEHPGWRFMMGFTTIPAILQIALSSLLTESPRWLLTKNRPREAADILRRLRGTAEVYEEIDSICSASDNESGDMGIWAVLRDPTIRLPLIVGVTLQVAQQFSGINAVMFYANLFFKNVGLQDPLMGTTLVGIVNVVSTGVALVLMDTAGRRPLLIYSCVGMVVSTFILTLALLKLLPFSGMISVGGVMCFVWFFEIGLGPIPWLIVAEMFPAQPRPTAMSIATMVNWICSFIVGLVFPSIQSSLNELSFVPFGVCLVLSLVFVLKYVPETKGKTIAEIQTEMHQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL83</accession>
    <name>A0A8K1FL83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007637</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000362">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="783"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="860"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="883"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="966"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="99"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="414"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="749"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1062"/>
            <end position="1296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1310" mass="146311" checksum="186F5208B6FD6B37" modified="2022-08-03" version="1">MATTKLLDARQSPQYATFDALERSYEGIKDKRGCVSRLLLSWVTPLMVLAHEKQLEAHDLWPLQREHQAEVNALRFTRDFQETQSIPKAFLRSFGLRFVLTGVAFLVSMLCNLVGPMVLKHVVGALTGQDFAVMTVTEWIAVLFVSQVVQAMVDNYANFDSELIAIQFVGSLKSLLYDKTLRLSAKSRKAKSTGEISNIFTSDSDSILQAAYLVHQAWLLPLQITVVSYLLYDLLGVAAFAGIAFIMLLLFINNRVSNLLFGYHRVYRSSRDQRMKRINEVFKGISIVKLNAWEEKFMERIEEVRKDELKNLFRLRMMASISITLLWGMPMFISIVTFGTYALVLKNELSPSIVFTSLALFQLIQGPLRQVTNVIIMLIQSKVALERATAFLEMEEIDPSNVQTIDSPVADQYIMKNTIIAIEQGEFCWDEGAVQLRDVNLNIKAGEFYVIHGPVGCGKSSFCSALLGDMVKTKGTVYVGGTVAYCSQQPWIQNMTVRDNITFGLPYERKKYEKIIDACALTKDLSSLPAGDMTEIGERGINLSGGQKARVALARACYSDASIFILDSPLSAVDAIVQNEIYNKCLLGLLRHKTIILITHNPEIIASEYITHAVTIDERGKLVETHRIQSRPTHDSLVSPLASRVYTMETFEVAVDKQGCREMNQDAVIKEEDALEQAEELPIVSPFKRANRKSFVEIENDTDSANKEAGRLIKDEARAEGRVKNHVFAAYYHALGGLPVVMLLLLPQVLGQAVQISSDFWLGSWSSDSLSGSTITTETRLGVYSLMGLGVAVMVMCRMVLTAVFGIRAAKSLFDRMTNALMHAPMRFFDVNPIGRILTRYGGDVFAVDAALPFMLTRSTAIVLSLTSITVTSAVVIQWKGLLVIPVVILYAKIGAFYIEPARELQRLTKTIQAPVLNHLAESFDGIAVLRAFGTQTVNRFRTTNHIKLDESNKVRYAQLGVSQWFSLRIQLVGTILVVLVATSLVMLREELAAAVIGLAFSYALRISNSLESIVQLISRVETAMVSPERMQEYIDIPQERPHRIPSLDPPSHSSWPTQGSIEFKSVSFRYKENDHLVLHDLNLSIDGGEKIGIVGRTGAGKSSLTMALFRINELANGSIVIDDVDVNTIGLKTLREKLSIIPQNPVLFKGPLRHYLDPFEQFTDDELWHSINRVGLRDRITAEEKGLWCLVEESGENFSVGERQMLCMARALSRHSRIVIFDEATAAIDHETDQKLQRVIREAFEQSTVLTIAHRLDTILDADRILVLEGGRVVEFASPAELVKKGSGHFFELMQEGGYLGKFLAQSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLB3</accession>
    <name>A0A8K1FLB3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012024</name>
        <name evidence="3" type="ORF">Poli38472_012027</name>
        <name evidence="4" type="ORF">Poli38472_012030</name>
        <name evidence="5" type="ORF">Poli38472_012033</name>
        <name evidence="6" type="ORF">Poli38472_012046</name>
        <name evidence="7" type="ORF">Poli38472_012049</name>
        <name evidence="8" type="ORF">Poli38472_012050</name>
        <name evidence="9" type="ORF">Poli38472_012053</name>
        <name evidence="10" type="ORF">Poli38472_012056</name>
        <name evidence="11" type="ORF">Poli38472_012059</name>
        <name evidence="12" type="ORF">Poli38472_012062</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLB3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272200" evidence="1">
        <location>
            <begin position="27"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="115" mass="13111" checksum="ADBCBDC22B864855" modified="2022-08-03" version="1">MVSASKIATVCCLAAASAVMVSTVSAYGYDDYDYGYGKNDYDYGYGKKHHKHHVRKHHKKDYGYGYDNYGYGYGGYGGYGYDGYGYDNKKYGNNYYDDGYGYGYGYVGKKYNYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLD1</accession>
    <name>A0A8K1FLD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polymerase nucleotidyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLD1"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="5">
        <location>
            <begin position="291"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="4">
        <location>
            <begin position="477"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="66823" checksum="A51C35E2F620F484" modified="2022-08-03" version="1">MRMQMLIQLMSWRFEEFVTSVEHEEFFDYVKDKLVSKEAPVKVQDFVSAKLPELVEAVKCEVEFQARVIFETSTIAIQDEQEWGPLDAVCLETDDGDTIAIRVYDVTQSAKKLVDSVIVSSDEDECSKASTLELNVEFVSPQERRRRPRTTARGKQDEELRSHHLDVMLHGEREEERVTKGVASMEISSPKAGVAVVQSDVDAEKSTKASTGSEPETTGRKRTMTKKRESYVDGVGVLSLPVPVWLDDNEYVNDTVIPVATRLGQEMVWYCEYTQARIDEVHNAIEDAIWNISVEVQAIWPDAHVACFGSFSTGLWLPSSDVDVVVMDIPADVFEASERAYGNGGVTPKKRPFVRGIAELEEIATRLRSQPWIKHIEVVRGAKVPVAKVVLADRDLRVDVSIENHHTRLGIEASVIVRDYITAIPVLHPLIMVLKQFLREKGLNNAFTGGLSSYCVSLMAVYLVERQGATNYSGADVGQLLLDFLEFYGTIFSYATTGISLKAEAFGEYFLDLTLGANGVPLLMPQLVIDDPVYEDGQHNAAAGAFAIARAIAAFENAFYAVTYHRPTKFTPTPLSQLVHWSGHAAEGAKTKPVTPRESTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLZ8</accession>
    <name>A0A8K1FLZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011316</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLZ8"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="77"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="663" mass="73166" checksum="58B6D95CC3A09648" modified="2022-08-03" version="1">MGASASTELPMSEIDFETYKGARYSQEVPNTREANRGPIYVTKPRYVDEKKLTLYENLLTGVAIQNGERPCYGTRTKVNGQPGPYEWLTYNQVLAHTETVASGLTKFAGLQRAGMVGIFSKNRVEWCLTAHACDRMSYILVPLYDTLGPDAVPYIVNHTELTTLVCALEQFDTVLKCKDECPTLQYVVQFENVTEKQRQQAAQKGIQLKSFAEIEELGKSFPVPADPPTPQDVTTICYTSGTTGNPKGVILTHHGLTILGYLTEQRLQLHPDIVHISYLPLPHVFERSVITSAVHLGAASGFYSGDVLTLMDDIAELKPTIFVSVPRLFNRVYDKIVQGVAAAGGLKKVLFDQAYAAKKAGLAEGHKTHALWDALIFSKIRQVLGGRVNMLLSGSAPLSAEVKEFFTIVFGCAVIEGYGLSETCGGLAVSGPDMPMGAHVGAPLPNLQVRLEDVPEMGYTSNDKPRPRGEIIVKGPVVFEGYYKEPEKTAEAVDKDGWFHTGDIGCWNADGTLSIIDRKKNIFKLSQGEYVAAEKLEVIFSRSKFVAQVFVYGDSFQSVLVGVAVPDPEVAEAWGVSKGRSKEESTVPKLIQDAEFQKEVMADLNRVGKDAELRGFEFLKKVHFHPDPFSVDEGLITPTFKLKRPQLKAYFQKQIDEMYASLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM08</accession>
    <name>A0A8K1FM08_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM08"/>
    <dbReference type="OrthoDB" id="127285at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008833">
        <property type="entry name" value="Surf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34348">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34348:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05477">
        <property type="entry name" value="SURF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="39641" checksum="B228F09C95BB09A1" modified="2022-08-03" version="1">MTGAVDVQALSRRELQYLAREFNLCRGNAKSETIGEHVTEFIASQADGLSRVQSALAQLSGDAKSPAAPAKPAAPVNAPEAKKTKAKQAKEPVTPKKTADAVAAKSPVEKKKTPTKKDATPAKKDATPAKKEASTPAKTTKSPSKATPVKATPPKSAATTKPESAKKATPTKATPAKPAAAKTARSPLATLKNSANTTVEALVESLDDIVFVGETRVKCITTGHEMKADRDVINAYITGKRYLRARNLKQSFASFAPMFVDHPDKDKTHLLWCNVTQTAVVRDLERVNAHINAARYQKELPVWQEEEAAKQAELEAQKEAAEKRKAQREAKKALEEEKETPVKKNAGKKRRASTTPNDGSKAKVPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FME6</accession>
    <name>A0A8K1FME6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plus3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FME6"/>
    <dbReference type="OrthoDB" id="166375at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115:SF8">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Plus3" evidence="7">
        <location>
            <begin position="375"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="694"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="552"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="790" mass="87274" checksum="2C50F1FD4EA57992" modified="2022-08-03" version="1">MPKKPRVIQESDESDGGHSSASGSVSSRSGSGSGSGSESGSGSGSGSGSDSDSGSGSGSGSGSGSDSGSGSGSGSGSGSDSGSGTGSGSGSGSGSGSGTDGSNVSPKKKRTKKARAPAVKKDKKKVAAKAKTPAKSRKKGGKDKTTLAKVAEEKSAEADDEDEGGRRKRGTKRLKVDDEDGEEDGEEAEDLKGLTEVEKEQRLLEKYEAEEQKNKEKELKKRLAASQGKAAEGTDEEEGEYMPSRRGGRSRESDRRKEALANLKSNKSKSADKTRSMLSDRLGNGSDSDEYDGEGRHDLAERRRKRQELSRRSGRHSDDDDDYSDDDGASRRKKSKLEGDEEGGDKNIKSALLMSLEGPKVDDVYEMKPQDMVPVNWAQANHYLLKKRSFFEQYFFEPYFEKLVKGVYVRLPIAPVDGQMVYRFCEVIGVTKGPKPYAFCGEQTLKMLVCAFGKSRIEWKISNVSGHSLREKEFLVWRATLNKERMKLPMYAEALKLVHDKKKIIKSHRYTDEEVNEMVRRKKEVGGSTVSLAAQRVRLERDIKAAQDMKNFDKALKLEEKLQKLLAEHEARLKDKSDEVLRINEINKRNREENMKKDLQAQELNDAMRDRMSHAEKLQFIRANAKKMYLSKDKIEKNLADGRLIRMEDGRILTLNKMHEIEALPDNFGKIKGNDVKDGGLEIDIDKLLAKQRERQEKEASKQDDSAGLGSKTDSKVEFVGAAPTSVTDIANSTIRIQDDDGTWMTLRAANKIVEEQKNKAHVPAEAKAGRRGITVKEYFDRVKKRRVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FML8</accession>
    <name>A0A8K1FML8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FML8"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF22">
        <property type="entry name" value="SLL0786 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="16995" checksum="F2FD405B33109D79" modified="2022-08-03" version="1">MPLEVTLATIDQGFDMCKKLRYQVFILGRGFDPELDVDEYDIKPTSYHFLGRDTETNEFVAVARCFADPESRIGKVGRVGVLKEYQGKGYGAAMMEAIESTVKDECHTIVLGAVMDKIGFYKKLGYARINDETFIDEIEQCWMAKKISNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP28</accession>
    <name>A0A8K1FP28_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP28"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF274">
        <property type="entry name" value="MYB-LIKE DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="31"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="420"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="51257" checksum="1BC901DD8EDF7F38" modified="2022-08-03" version="1">MATRMQERVMSPQSSSSSEDGEKRGSKAADKRKQWSREDDLVILQFVKDYGIKRWSKISELLPGRTPKQCRTRWLNFLDPSIDKAPWRTEETQIIFAAQERMGNKWAEIAKLLPGRTDNAIKNHWYSTYRRRCRQAAKGKEKGGDEESTTVSTSVKHKADTSTIPTINTSNNSINLTSQQTLKREDPSQFEADAPLYPSKRPRKSPTDHEQFFSALSYLSPSPHGRAPYLASPATEAQGSPVLASKPATSPAFRSFSSGSRTIPPLNTNQSAREPPTPSPLNGMLFRFLTSPSTTNMFQFPDEPAIHPSVSTRESTPPRRGFNLQNQLSAWKDFGVTLTDSETTSPSSSTTSPLQLKDEDKQPECNQDNVHSIEADRKENIVPSASFFDKSRVAMLRRGSAVSRQRSNSADLFLDCVEMLSTKSNGDDRNTTPTSTTSESEDNQSEAHGPSTTKVSLSARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP82</accession>
    <name>A0A8K1FP82_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP82"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="118" mass="13276" checksum="5DCC9DBFEF9BA296" modified="2022-08-03" version="1">MNGIITINGDLNGKNLIILALCRRHTELRRHRSFLIKQRTFKMPFVKVYTNVKRAQVDSKRALAAFTTALAAAFYRGEAFVMVKLEPELELSMGQSTEPCAFLQVRNTACSTTTAHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPI9</accession>
    <name>A0A8K1FPI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPI9"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="3">
        <location>
            <begin position="202"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="30026" checksum="EF2E14ACE9CAC120" modified="2022-08-03" version="1">MNEMTPLMQQVPYMVLPGNHEAECHSPACLLSTFKKDHLGNYTAFNSRFKMSSAESKGVKSMWYSFDYASVHFTSLSSETDYPDAPSNSYTLTHKNGGFGNQVAWLEEDLKKAAANRANVPWIVVTMHRPIYHLEQVDANGAPTDYSKNLQSAFEELFLKYNVDIVISGHRHRYERQMPIARNAAKTDGVSSDKKTYTNPKAPVYLVSGGAGNIEANELNNNKASWHVVQSKDYGIMNVHVGPKSMQWTYINSDSKKVVDQFTITKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRL3</accession>
    <name>A0A8K1FRL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRL3"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="126"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="294"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="602" mass="66857" checksum="5250255DB878DA5F" modified="2022-08-03" version="1">MLTSVVPSTPSKPPGPALGLVSMKRPSSKRLLDVASSITTPPQFLSRSSSTKRGITRSPTRRSLGAVKREIPPHLVKLLQKTPEQQARVEAVKAILADEPGHRNELSLDIVYDWMLHNCKQYSNNIFGSAPEYIRREICRQMRLIKATTNQLLIRQGDTGDRCYIVIDGLVDVYIKKETRPSVDKSEDQQDEAPSPQRTSSRRGSIIGPAMMDPAALTKEYGDMVANLGPGAMFGEVVLMNPSARRNATILATQYTETCELIFLERADYIRLVRGASMEASHYNQAEILDHMYLFHGWSKHDKMRLVSGMRSLHFATNDYLYRAGSDAKWMFIVSSGEVLERINWSVASSASSNSLPSSVKPGDVPEKKVNIDLLIVGPGDIVGEFPFVKSKWSSTSDIRALSDVHALALDRRVYEHMIVQATPESNRAAVMTYQRLQRLCEEREDWRQQRLACGVAYPSAPISMTWQVMRMSNLRCPRCGQRGHLAGDSGRCSNPSPKRLNGANSGSTLPLVALKRRSVHASRRASGIGSPAKKVVSETATSLLKELFDETYLPSAQEQLAQCRLEHERRRDGQSGTGPVLPSQRSASFPVQQSTHGTRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTB9</accession>
    <name>A0A8K1FTB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001589</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTB9"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="148"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="188" mass="22205" checksum="EC28103BF344112F" modified="2022-08-03" version="1">MVSLKLQKRLAASVLKCGKRKVWLDPNESNEIALANSRQNIRKLVKDGFVIKKPQVIHSRARFQKRNEAKRKGRHTGIGKRRGTANARLPLKVIWMRRMRVLRRLLRKYRDAKKIDRHIYHELYMRSKGNQFKNKRVLMETIHKMKAERQREKTLKEQSEARKEKAKIARERKEKKAAAPAAAKPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2S9</accession>
    <name>A0A8K1C2S9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2S9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="821" mass="89993" checksum="F40585D7606383CE" modified="2022-08-03" version="1">MAEYDDASATESEYYEEEENEDVVLIGSSSAPSKELSIAPSLVSSNGVQASKPTKETTGFHRPAARKSVVSSHMVRGLPTKEHTKHTQAHAADTSSPVSVDAFSAMLAQVRANAVPSKFSRAKASKQQPAQDTTTQQAPTNATDTSSTHGPSGFDGCPPPDTGDSSLLALSPSDAAGKAVEAKSTTTTTSCKHCSAQIQSSDPLAGGADACASCQPKLLGDLQPHESIQVAENGEEEPTCAVESSTNYVPEPPSTHTECRHALAEDGCAETKPQQVDDSVCIKSVDDQDHQPKRESEKQEPEGMTKVKKIDQVNLQDPVPLSPAEAALKGSSAEGEQGAKGDTAIPKETASVSPDLIAVESKQNTLNTTNMEAQAILQIVRYLVSKQTSAMWADHGRDHSVHIAIKRNNDRFRKERLSIVSKYANLRRQSVFFPLSLDERLQMRREQNALLEHAIECATIEIVGLSYLLRLCGSNLPPDVVDFVTRYSEERSSSTPGLAEFIPVITDKPTPVFTSEADEAASDAMLMSSEPIGIANVAIARICPSSTSLNTPMATGVTNTSKCRANGKKKKKARPPKCPKCRGHFCISVTKLLVPTDKMFCDCCVRLLPEERFTASEWESPGSRRCLECTGDLDEASTQELKKIKMIEVEIKHGQGLFPALRRAWMAVPTTGQIALEADHEVLQHPAFKTHQDRLIKSANHWHGMRMRYRELVANDSSAVMLKRDRALYYIYREARRKESDLWTARLELYSQLMSVIRFRLRQDLATERSHVMTQQAYELMAKQPSEDTRPTKRPQDAPEATLHASKRARVTALDCETVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3L2</accession>
    <name>A0A8K1C3L2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase assembly factor 3</fullName>
            <shortName evidence="6">SDH assembly factor 3</shortName>
            <shortName evidence="6">SDHAF3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008473</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the complex I LYR family. SDHAF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3L2"/>
    <dbReference type="OrthoDB" id="278329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006105">
        <property type="term" value="P:succinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20270">
        <property type="entry name" value="Complex1_LYR_SDHAF3_LYRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008381">
        <property type="entry name" value="SDHAF3/Sdh7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137">
        <property type="entry name" value="DC11 ACN9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137:SF6">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="105" mass="12508" checksum="890F7FDD50294208" modified="2022-08-03" version="1">MTTRAEVLGLYRRILTLHRRKLEPRMRVLGDAYVRDEFRRHKDAADKFVPLFMQEWEQYVTMLSQKQDRFGRELSESERALMNSEQQEKLQSLRDAAKSVGESMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3N3</accession>
    <name>A0A8K1C3N3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3N3"/>
    <dbReference type="OrthoDB" id="79589at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47284" checksum="3BA5C715932BBD22" modified="2022-08-03" version="1">MSETARDDEQDDYDAAYADDHEDPDDDGDENEEDDAELAEMFAKVQTIQQNEGIRPKSSRSETADSPLQVKIPPRTTSGSGITPHSSRSSPVSSAASSNGSTRSPDGITTISRKSLTTNKNRAAVDVLLGVKMPSLFQDKLVETAKRNSQTLEQMKQKVVAAPPAKIAVRSDMKSGQVKDSFLHVHAFKQRVETLAAPKRADSGRKFATDDEEKHCRFQPKKKKGGSANTRDDFDDDDSGGGDRTHEFIARMEAAERNRQKKLELTRGEKDYLANLSKKYCPNCQVPQSYSEFRDKKKRCQMCGAEFRLPHAWGDIGHEFINRISDDAKLREERKEQIRAHVVTLEATHGRVPKSSTQQYYEKQLRQRQDPKSFLDRNYYTTSATASTSASNSKTRLAQAQLQMQIQAQRAKLLTSAQPPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4F1</accession>
    <name>A0A8K1C4F1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4F1"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ras-associating" evidence="6">
        <location>
            <begin position="147"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="293"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="5">
        <location>
            <begin position="425"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="65251" checksum="63694557BC61B526" modified="2022-08-03" version="1">MELLPVADDDRSRDSARFTRPSDTNRGSLVSASTSAEQNPRVKRSMTSTSSELDAIAMAAEATSVDDDEDVSNAVDLAQTISLGVTEDEHDDLIPRGTPRRRPTDTISLSNPSTSMMAPMRRNDSDRSISSTSSDRKRNYLVKSEDRSGYARIYFENQSFTSSTVFKLTPTTTVLEVRKSMANKIKIPSADFSYYVIVLVYPSDNARSMSARTLRDDELVLPLVEKLNRARASIASSEDMANPPRPKPKHRSRPPLKFILKDVRGAPLDLDEDQVKKETTEAPGLTVPALIGKGVRSGYLQKASVKDTNVWRKRWFVVKDDQLLYCKSATNQRDVTAISLLGAYLAKARPEVKVPFSFELRTPRRIYQLCANSKEDMVQWIHALHVQIGISTENHRLYEAEILITEDAVSRNEEVNFSPLSEPSLLQRVLAREDSLKAFRDYAYAVGAQPLLDTWIQCELFRRNCLEREIGGAGGSGKTNKRSAKEEWEHLGAIIEATEALSMINAAEVKQLRESFQSELINRRLSLALHASMNIEYPRVELIAAVHQKIFEAIENGPFKQFLNRHGYRVLLERVMGRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X0</accession>
    <name>A0A8K1C4X0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X0"/>
    <dbReference type="OrthoDB" id="7250310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="514" mass="56273" checksum="A0B6C9B894558DBE" modified="2022-08-03" version="1">MKDSRALASTISIDNRCFGSNFLTDLLGKVLNLPSLSTRELNALQCKRCCYKYPTLFGWDYDTSCPQRKIWWSAPCSLECCEDMDPSTAITATVKLTASVTTANTAVVAGLSTPVKLDGKTVHQIITCTSFTAGCTYTHKLSELFVRSNSWGASVASKYKVTDYVTWRYTVGVENWKPWNDADKLTFKDAETVVYVEAWTPCGRAFQDSFKVVLHPHASHNACADFPAMWVENTAKPRTVASHVCAYPQSDFVLMSFKFDSDNCKPQEASTVKGAYTDVRCFVTLAESGALDKVKEVALPLTVTPDASTGRIQLSKQFALELVHELTTASITDVRVRCDFKYTHYKATSFEMEPCSYSFSITDCDPPEVETKGQEAVCKASECLDSSGIPGPFEACKGTVFTTTSSPSLATVVKTLTGQCCAQCSKLLTCAAVPETIGTSGVMRCTPPKAVAVLIMHKAHEPVNDPQFFLLLAVVSAMLAVLALLVLKHRRRNASAPKEPIDDMQMPRLTADIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C567</accession>
    <name>A0A8K1C567_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C567"/>
    <dbReference type="OrthoDB" id="98643at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="30074" checksum="9F06A3B25567F331" modified="2022-08-03" version="1">MVTEMAADSCVCLCYSPIYSIKNTFLSSSISGIKNTFSMSHPHLAHKLPWAELGRVVKRVATPLPGNPKFRLQADEEKVVDHFAKCLASTIAEFAATDKSSAEVKKYFDPEQAWGGSPWNGEVQAHQNFYYPGYLMTIIHNYIVFNLIVLEPDVFVPLIMTNDGRPSHLMEYAYKKSKGHPDWLVEQLIPAFYYHQDTRGYKHLRLKPVTAEVLDILREQCKHLFRCLYSLSGDNASSDWVVVRRSMAINFFHKKYLREYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C672</accession>
    <name>A0A8K1C672_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C672"/>
    <dbReference type="OrthoDB" id="10579076at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="20480" checksum="A6EB5F541497ADD5" modified="2022-08-03" version="1">MALFRSFDVLFSVSECLAGIILVCDLHCWDYRCVNVITWVLWFLWVLCLDALTPPARHYLRFKKFAATPIQLFLLYAYLGVPLVLYVFVDPKLTSRLVYSVNSVEIRTDTLAVARMLTLALWQTRLLWDLGVRDDSEFIFLRDLVEYTVPRDVASSSDDGLRASSANAIVPRAVVQPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C824</accession>
    <name>A0A8K1C824_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C824"/>
    <dbReference type="OrthoDB" id="67445at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050500">
        <property type="entry name" value="Phos_Acetyltrans/Butyryltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004167">
        <property type="entry name" value="PRK05632.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007233">
        <property type="entry name" value="PRK09653.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356:SF3">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="8">
        <location>
            <begin position="254"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphate acetyl/butaryl transferase" evidence="7">
        <location>
            <begin position="423"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="768" mass="84107" checksum="AC94103EF92DAE5F" modified="2022-08-03" version="1">MWRLGRAFHRVVPVTRSPWRQLRPLMVSADGRVPVDSLYVTSSDMVRKTSPVLLGLSDILEQKFKSVGYFRPIAPPTGSDHHLELMKSELDLPHEINALYGVSSERALQSWLDGKEDDLVEEILTKYEQVKQSHDFMIIEGAQIMQHETSLSWKINVDIAKALGSPVLLLTDLGTSPAISDALLAREILTRSVLGKEQVEAAGLTYFGTIPNRVQASDRDALRSTLRSAFAEKKLPFLGFLPHDELIASKRLNEVMEKLGAAQLFGEKQIANNVVVSDAVVATSSLKDLFSHMKKHKDGLLVITSADRSDVMLGLLASRIPGVLPSVSGIVLTNGDYPQSNTHEILQGVSALDKTGLSIPIFSVPEDTYGTATKLSNISTDILPTSVRKIQQCRNLFNEHIEKEQLIGELDQGVVVHRSPKQFKHFIFNKARDVQRHVVLTEGEDIRVLQAADEVLRQRLSQVTILGNPDEIRLHAKTLNLDLSGADIIKPCESPLLEKYAQHFYNKRKHKGVTIEFARDTLADETYFGTMMVEMGDADGMVSGACHTTANTIRPALQLIKTSPDRPLVSSVFFMCLEDGVRIYGDCAVNTDPTAEQLAQIAVTSAESAEAFGMIPRVALLSYATGDSNTGPIIDKVREATKIAQEMRPDLDIYGPIQYDAAVDESIAKTKLKAIPSGAKVGGHANVLIFPDLNTGNNTYKAVQQSTGCIAIGPMLQGLRKPVNDLSRGATVKDIVTTVAITAIQAEGIAAQRELSKQKQTEDVIMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C861</accession>
    <name>A0A8K1C861_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C861"/>
    <dbReference type="OrthoDB" id="186607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="330"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="616"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="953" mass="104769" checksum="516A07F24372381A" modified="2022-08-03" version="1">MPPKGRGGGGGGREGGGRGRGGRDGGGRGGRGGEGGGRGRGRGAGGGRGGPLAPPQRPVSSAKSTQVTPPLPPAAPVVVRPLTTEVAQLAEDLEEKASVSEAVVSRTTGSSDLPRRPGFGTVGRPVELYANHFRVKWNEDMGDVYHYDVTITEAGGRKIGTGDLPPKSLAEKIMRALVTAMREQYPGVAVVSDFRKNVFTPTRLPHGAVLFENLDIGERRGADQTPRLYQAVVKAASPVEVRMHQVTELLNGRLNYTPQDAIQALDIVLRYSAALRYTMVGRNLYSAAGAVPIGEGAMAWRGYFQSLRPTQNRLVLNLDLSTTAFVREMEVLDFVAEVVATRQSNAVPQSLRPHQYAAVNKAIRGVKVETTHRPGVRRTYRVNGLSPKSAAETFFEDDNGRRQSVAQYFAQHYRALRYPQLPCLHVGAVNKKTYFPMEICKTVAGQKCPRKITDTQTAEMIKVAATKPQDRKAQIESKVREAHFDRDATLRSFGLEVDPNMVTTQARVLPPPKLAYGRNATVNPDANGTWNMRGKSFVQGQQLKSFAVISMDDRLEEHLVDEFFKMVLNQARELGMGNLTRSPPVVWPSGRNPSVRALFGQALDEARRVYGSPAQIVWLINPRQDARTYGELKRVSDTELGIVSQCMLSKFVMRPNPQYVSNILLKVNTKLGGRNATLQGSMPQIVDRTPTIIFGADVTHPSPGDKSRPSIAALVGSLDRAFTKHASVISAQGHRVEQIVNLRDMVVDLLREFYRASGGTVQPQQIIFYRDGVSEGQFDMVRNFEVTAIREACALLSPTYQPAITFIVVQKRHHTRLFVSNPRDADKSGNVKPGTVVDRGICHPTEFDFYLMSHSGLQGTSRPSHYHVLFDEIGFSADDLQTLTYRLCYTYARCTRSVSMVPSAYYSHLLAYRARFFTPDGMDSTSIGGASTETTNLEMAAVHPSLKPIQYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C977</accession>
    <name>A0A8K1C977_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006934</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C977"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="6">
        <location>
            <begin position="306"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" mass="60330" checksum="6507FCCB782376DD" modified="2022-08-03" version="1">MADDLAAAAARVNICLGYEQRMLEKNAQQRKLPVTVVSGFLGAGKTSLLHHLLANRLNLRIACAVSDLAAINVDELLVTDQTLFALQRSQSGVAVASAKGGVAAQSRQWVKTYKHNAEVYGVASRSVDAFKDVIWEILQEHEEPFDYLVIETSGTTDPTQLISAVQERFGKMTRARLDSVVIVVDGDAMAQDAKQGRTPNNVAIYQLECADVVVLNKVDLMTEEDKQRAHQVIQQYAPGARVYETTHGQVYLPHVLDIAPPEGVHDAVSHEKVEAHWVCGSDNATRRLRRDDVALSSRSGSSSSSFSSVAYEQTEAVSLRQLHHYVRCGLPRGVLRMKGVVCLADDGRRHRYVVQLSGRQRLEIENTGPWTTAPKTQLVVIGTGFDEDAVRNDLVSILTASVDEPALSTETVQSVDKLRADPRFDVVQVLPRAVQFRLRIPSTRLDEATVKHYDHVDLNDLIRRLVHEVNALGGGAMLVPVVLKKEELTANDGNHHHHHFDDGLEVVAMAATTGETTLVDMWDAVDARAEHIVMEVKEKLARCMCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA60</accession>
    <name>A0A8K1CA60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA60"/>
    <dbReference type="OrthoDB" id="64619at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="39403" checksum="1D30D39EC23EEE1E" modified="2022-08-03" version="1">MSEVARAIALIQELHGNGSTTDTAPTPQTSSLTEEQTSESVKRELVYLRARVRKLEAERTSLEERTKATRVWKQVADRQSAQRYAAELENAKLRVILDTQLQMGKQLMRVLEHESPQLVPSGPHFHISFPDVLMNSRAEQTACVDKLYQQSHDVFARFPDGLTTIVREMSVEEDADGVITIEARMGWVLPFAADRVLDVMWRLTRTQVEERGHVTEEHGSLFVEFDAAKLRAISAAGWQLTKQYASQDGVPVTLVSQSSAKFTKPSKGTGVAVGVQYQGESWVRLVGSVLNDQAMTSIQVVRRDRSAYVTDKSSAQQAIAGTSADHMLAFIDLELTRVQQCIENLLFAPSTEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAC5</accession>
    <name>A0A8K1CAC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAC5"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051262">
        <property type="entry name" value="SMP-30/CGR1_Lactonase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572:SF5">
        <property type="entry name" value="BLR2277 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572">
        <property type="entry name" value="LIPOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="29849" checksum="93134E839576070F" modified="2022-08-03" version="1">MDVIRCKGSNICSPFTSPDPHDVAIYYVSAGTGEIYAYSPPQGTHTSVVFSGGEPYGAKFDASGRLHIADCAHTALLRVDDSGQPGVMVKNYEEKSFRGPSSLAFGENETIYFTDSGPMGETTLERPRGSVFCISPSPSGGQMLRPLAWECLAHPSAIATSPTDTKVLYVAEQMANRVLRLIQRPANTYHTSVFHQFAGGLGPSCVTVDRHGSLYVGHFDYSGPRRSQGKISVLSSDGVVSRTLDVPGIEITGICLSADETTLYVTEASTNALYRIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAV8</accession>
    <name>A0A8K1CAV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAV8"/>
    <dbReference type="OrthoDB" id="69983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="48482" checksum="D90B4547A5EB45DD" modified="2022-08-03" version="1">MSTETWPADDGEDALTAALAFVDEFHAPATGDADPLDGLWDDDALLTELELVGTLPELSSSDASVGSPSQNSSGKEAIPTAKQGRRRTARRDELVYLRSTVQELETKLSSLTETKTSGYPIQDTWERMAQSQQQQRQDAEVENKKLRVMLQDQLRLAESLEGLLKKRSRVAFTSTAPEGSAKRLRLPSATSSLDNPKINDELAQIVTDMHRELDTLLADPRLQMMSTTPRRFVELRNDDTKGTTVESLESRLLPFDFKDTAEATWNIIINSSGHGHNVNRQMLQEIKMTEHSFFKSLERPGDTPLHTKPFRSKLTCRRFILPDRIVIAGCALNEGTEAPGSPMEGVCTRTRVWHILRPAPPQLTQDPSKPATLRQIVHVVSPEAIPTTDKDGETRHKVGVLTNFVLKGADHHLNSGNQLLENALLEKMSNLGLGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB48</accession>
    <name>A0A8K1CB48_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB48"/>
    <dbReference type="OrthoDB" id="75145at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="28658" checksum="2EAA9ACD74D4B78D" modified="2022-08-03" version="1">MSLTFLRHSTRRSFDHLPSVPETLDDSVGAKQKRKRSNPRLELLNLRSIVSALETQLSELRQLRRDPETFSADGVLLSSVWEDVVSRQLQLRQDAEIENAKLRATLLEYIRVAKAFERLLRKRNSIELVPAPIAFVRKRNRLYQQKNPLDEEYIMDELSHSLIGMYSHVDVVLRDKRFENSGRNPIRDFGLHPDTSTGTSLEILGRGYSHSISKPQLTRYGGSRIAKRSIRCIIAPMQVNQRLQQTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB58</accession>
    <name>A0A8K1CB58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB58"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="411" mass="47537" checksum="ED4F0AB017B0D7A5" modified="2022-08-03" version="1">MAEDGDDVLDATLHAALAFVDQFYEQQDMSIDLDVAGYHPDKDLNHYSPREDTVRRRRHRKRTKEQLGELRARADVLERVLNSMKSAQYGDDDVMQSENETRENIDHHPEWEEISKRQEEERKQSTIDNVKLRDVMDDQLKLARTYDGIIRKRPNPEEFMPFHIRDKRQRTMEGSKWLNSPELKEDLLQTVGQMFTELNGVFADPRFDSNANAGRFRIVGSRCDEGIVESLDSCMLPFDYMDTADAVWNVIQSNRETRIWNVREKLEQKETVTTEILDGVLESPLKNGAFHGKLVCRQIIEADRVVILCAMAIDMDEVQGDIVRNMHVRSRAWHVIRPARVNTSGKCTAAVWQAVHLIGPDRRGEDKVASCHQRLCPLVRNHMIAGITAMLEGRNQLVENRLLDSMLMRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ6</accession>
    <name>A0A8K1CBQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="2">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000151</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBQ6"/>
    <dbReference type="OrthoDB" id="686384at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06155">
        <property type="entry name" value="eu_AANH_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000194">
        <property type="entry name" value="Diphthine--ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1490.10:FF:000001">
        <property type="entry name" value="Diphthine--ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthamide synthase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="737" mass="82110" checksum="1AAD4D1B96276817" modified="2022-08-03" version="1">MKVVALVSGGKDSCYAMMECVRHGHELVSLAHLHPPLHLAPEEAEIDSFMYQSVGHNVVRLIAESMELPLVTETITGTAIKTDIDYATTTEGDEVEDLYRLLQKVATQFPDVQGVCSGAIFSSYQRNRVENVCARLGLTSLGYLWRRDQEELLDEMIESGIEAILVKVAAIGLQPRRHLGRTIGDLQMDLLGLQEKYQLNVCGEGGEYETLTLDCPLFKKRIVVDSSRTVLHSDDFFAPVAFLVVEQCHLEDKDEAVDASVLQRSLPPLFTPVATEITSPLVTPRTLAFDENPERALLPSIGSFRDQFYVSGIMSTKSAELTLEEEMQDVLEQVKRTLAEQQMTLDDVCFVHLYVRDMNDFARINAEYCQHIPQYMPASRSCVELRSLPSRVLMDCFALRGSGVTKLEKPRVQRDVLHIQSISAWAPNCIGPYSQANILHKSLILLAGQVAFQPETMQITGKDHVEQTKQCLRNAGRVFEALESNLRHVVSGVAYVVAPGDEEEALKRTMQTCHEQLITNADLRDEFENVPDSGESDNGVEEEELDHAALARNTPLLAVALSHLPRHALVEVELQSLTHRAFTHTHPRSSTLPPKEAIGWRIQTQTSSIPRAMSLVMSTAEALAGNTSTPVPTTELETLCTMLMQHVDDALMAADLPWDRLFHLRVFYRPQTFPSELEIANALSRVLARGIDAGDLRLPALTFVPVEAIHPNAQLAIQATAQDLDKLETDLWLQKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBT7</accession>
    <name>A0A8K1CBT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000196</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBT7"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="295"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="367"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="433"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="457"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="723"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="765"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="824"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="872"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="888"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1013" mass="114478" checksum="99E5AA040A8D0A43" modified="2022-08-03" version="1">MGLERFPVDEGALPRVTISTKRLDEWKEVARDEIMRALTNRHSWYNAFTEKVRDGYEMMADRPNMKAFLRGVPNSADKNVLIRSTLENTTLDDIVYGTYCETTFDVRCQFAHMYEENFLDGGLLHTHETRTPEDPLHFVGIKWIAFRSPAPAIVTSRDFVFFTYDGSAVDAKGQRVLFRFLRTMPMDDVPVDSSKLPPLVRGKISNIHFYRESGNNVEAFTKAMYSNAGNMPSWVVTKTISFIYPGVENIATVGDARALMINGHTHLNGARLSGQKNSFGSSSSSVKSSRPTPSIAASNTCGVCYQKFSLTRSKRPCQGCNQTVCKRCTIQLCLFDEQKQISPTSVARVRFCMNCVRSARNEANMSKLNLPSTTSLTSLNSSKSSESRFGHSQFSESMRRVPSQSSFVSQSRSQGQNPEFDSFIREIHDEEYANPSAAPSPLPVQRAPSPMRPPSQPQYHQPQYVQSPANYQQQQPQYLQSPANYQQQQPQYLQSPANYQQQQPQYLQSPANYQQPHQPQYLQSPANYQQQQPQYAQSPAHYQQQPPQFQQPPAPYLQPPPQRPVGPPMPQAQYQRPVGLPPQQAPQFEEDIDGRDTFSEFHDFGRETYSEFHDDRETFSEFHDRDTMDQFHDRDTMDQFHDRDTMDQFHDHGDEEYDITDVENFRDSHYDRNSELVVHAYGSQAGAKPTTQFSEKYRQSEEFSISGSYEEQSGPLGAAVDNVIEEGDEEEEEDEHKGRGSFIPLTLNEAPSTVLSMSKRVSDVPQQSQAYQPQYQPQEPQYQPQQPQYQPHYQPQQQYASPPPPPPMQPGRKFSMPMALDDLNGSQPMSMNRSSNSPYQGQQKQMHSSYGSSPFQGQQNQMQSSYGSSPFQGQQSQVSPYQGQQKQLSSSYDGSQYQGPPQQDMTDSVRTATRHQSTPNLLASYRSHKRTNRLAGPGTAPLQGFLKRAASDDTGTNTGNTYINEDLSASMRTGLNLNDSSRANPLANSYSGRAMDKPVATYNAPASMRGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBZ6</accession>
    <name>A0A8K1CBZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBZ6"/>
    <dbReference type="OrthoDB" id="30343at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002461">
        <property type="entry name" value="Zinc finger matrin-type protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="6">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="241" mass="27035" checksum="45D4ABD2A7A8C3D4" modified="2022-08-03" version="1">MSGIKKGVANVTRQTWDKQEYERLAQMRANGELPLEEEAKKVVKSNKQEFAAAEEGAAGPVGSARAFLKARAQRVTLEDNVGTVRVMKGEDAAKTNGYYCEVCEITLKDSVAYLDHINGKRHLSKLGYSMRVERSSVDQVKSRLQSAAKRKYDPVITKKLDAMEEYEKKRRELEKEEERRKRQRKEEKKAKKNAETAPVDVETTQTEETTGEASTEPQVSAEEAEMMAMMGFGGFGGSKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL4</accession>
    <name>A0A8K1CCL4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCL4"/>
    <dbReference type="OrthoDB" id="164533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="221"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="488" mass="54887" checksum="F5ABC724CABC44E7" modified="2022-08-03" version="1">MEVIGAAAPVLGAAAKLTVELYGSRKMCLALIDDVKAMESRLETLQDHDAVVVRDALDQYSLLVTKIRDTLECHVKRNILHRLFVHWSLTSSVAQFYKDLEKIERLLPLDHMIESANRHEQNMKSHDAIAASIQETNEAVINGADKILRTLEEHREAFAQELKRTDFDEEDVADFKKYIKRVRDQGKYTQEEVDKLVKLLRSSSKVLNIAEPSVPKWYLPRDDISYADADPFATSADQLRAMYHGTIYGGSRVVIKTVRATGDPADKKHFDREADILFSCKHPNVLAMYGATSYSDPMLIAVAFAALGNFRDYLAVHNNRRRVWALFLDAARGLAYLHSHNHKIVHGNLKCSNLLVLGDGTGVVSDFRFAFVRINSALSVKPVTSSHNWKSPELFNASDHKPSFKSDVYSLGMCLFEAFTGLVPYADIDVDEAIDMIIDGQLPAIPAGVNVPDEAWDLITRMCRKNSKERPTMQQVVNEIESLARQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCV7</accession>
    <name>A0A8K1CCV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCV7"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="145"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="253" mass="28452" checksum="A1AE893ED0859ECE" modified="2022-08-03" version="1">MDFRRLLREERQRALQRKSQGDETAAPTENEESASNDEKAAEAELSNEPLTGWRIRPQLDLTQFRVDGIRSVYYVPEWLTQEEEDAILGRVYGAPATMWVSLKRRRLQMYGGQVKAPFSPEPLPLWLTQIASGLVDAGVFVEATRPNHALINEYGVGEGIMPHEDGPAYHPMVAIISTGADARVTFAPHRKWTAETPDVPDTALTEVSFMVRRRSLLLFTEDAYTEYLHSIDGVELGKRVSLTIRHVHVAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDF5</accession>
    <name>A0A8K1CDF5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDF5"/>
    <dbReference type="OrthoDB" id="59124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="108" mass="11961" checksum="CDC9CA1D6ECE590A" modified="2022-08-03" version="1">MGPRSNLTAAILSGVTGMTLAGVSLLAYVRFAHPEQFAETSVRMSHPELADEVSQKWGLFGTGLADAIPDVVKDALRIKNLPERIEAQKKKREEQIRQTIEDFRPKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEI0</accession>
    <name>A0A8K1CEI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEI0"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="281"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="42461" checksum="E7DC00681AEBA3B5" modified="2022-08-03" version="1">MASLAASRPVVSVLSIEGETATVAGQVVLPAVFTAPIRPDVVNFVHTNMAKNNRQAYGVSRRAGHQHSAESWGTGRAVARIPRISGSGTARAGQGAFGNMCRGGRMFAPTRIWRRWHRKINVNQRRFAVASALAASALPALVTARGHRIEKVAEIPLVLDDSVESIQKTAQAVKVLAKIGADADVEKVKDSKKVRTGRGKTRNRRYVTRRGPLIVYANANGAEKAFRNIPGVELANVERLNLLQLAPGGHLGRFIIWTKSAFEKLDSIYGTYSKKSAEKNDYSLPRHIMNNANLGRLINSDEIQSVVRPGKYSSFRRHHKKNPLKNLGAMVKLNPYTLVARRAELRAEALRKEKKAKAVATKRNTKNDPKRKEQSRALYAKNNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEP5</accession>
    <name>A0A8K1CEP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEP5"/>
    <dbReference type="OrthoDB" id="66207at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="99" mass="10709" checksum="A2833483098BD38D" modified="2022-08-03" version="1">MGHYGLPIGTILEAAKAQGMLTGMIVTCRVTHATPASFAAHVADRNNENEIARQYVANKNLDFVLGGGLRHFTDPMLANLTASGYSIVRNYAQLLDYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEU0</accession>
    <name>A0A8K1CEU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEU0"/>
    <dbReference type="OrthoDB" id="203703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="95"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="440" mass="49060" checksum="1110763BF716992E" modified="2022-08-03" version="1">MGAGSSSAISTRALEEFADALADPNQQTLVITHRDLLVIPPTAIAQALHLRELRLISTRLGSLPASFGCLSQLERLSLERNDLQTLPLSFHELSRLRVLDLSHNQFQGLLGNFCNLVQLQQLWLHRNELKQLPIEFGNLRELVLLDVHGNRLTKLPKSFPCLVSLTRLDASGNRIKTLPEAFGNLQALDYCNLSGNVLGSLPDHFGMLERLRVLLLRQNALIDLPPSFGNLQALENLALSGNRIEVFPSASLGRLNKLHSLTYAENRLKAWLVGDSTDEEPVGGLFGLTSASFVDFGDNVLVSLPSTSTGWTRLTHVIELRLHHNKLTSLPDGIAEMVRLELLDLSYNRLSYIPPSLCRLARLRRLDLRANALEALPDNLNEFQTLEVMLLQKNTSLITLPDSLTTVRTLQWLEIDKKCFLALSESLLTFCESLKTFSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFV5</accession>
    <name>A0A8K1CFV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFV5"/>
    <dbReference type="OrthoDB" id="45882at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11369">
        <property type="entry name" value="RNase_PH_RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000017">
        <property type="entry name" value="Exosome complex component Rrp42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033196">
        <property type="entry name" value="Rrp43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="10">
        <location>
            <begin position="47"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="208"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="31100" checksum="3FA3918D831C8B27" modified="2022-08-03" version="1">MSMVDQSAGVALSFDSDVYRKLFPREYVNKCIENNVRPDSRLLEATRPVHIQTNVVKTAASSSLVKIGNTSVMTAVKLTVGTPAVATPDQGEIAIQVHLTPLCSTRFNLGRPSEETQSIGSQLTRIITGSRVVEMSDLSIERGKSAWKLMVDVYGVDHDGNIHDAALLSVIAALKTLQLPAVTINESDHVVSIQPDGELMPLKIQHTVYSTTFGILNNRVIVDPTNEEELLASALFTITYNSNAQLAGVHKPGGSILEPQTLHHCMSIAKKRAVLLAAAIDKAIHTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFX9</accession>
    <name>A0A8K1CFX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFX9"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475069" description="Expansin-like EG45 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="49878" checksum="0F504C37E691C7A1" modified="2022-08-03" version="1">MIQCWRLVIAVVLLAARSTLAVDVNGVVTQYEMPKPDVGSCRLKGIDSSSDNFKYYASVSAQNVKSMNNGCARCIKVTKDGGASVNAYVLDVCQGCNDGEIKLSKTALSELSINPNSNNATVTYKYINCPSNFVKGNVKACLMEGASNSYIPLQFYNTQKVLSKVQINGNDVKQDKYSFFYYATPQQGNSPGSTWYKDVRVTLTSYDNETLSGSFSFDGTTGCASSAVQFSAASTADGEDDEDSSTSDTGNKNSVIIPAALGGVGGLIVIVGSIFIIRRRRRTPQDLNADDIDNQFLSPKSKPPSDPAMEYYHRDSSDGPTDGEASSPAAVYSHAVSPTVAAPSSVPRPAPRPTSETPIFQQQPQRYTAPSYSNSKPPSPVGRPQNSLNTLTRDLPVIHSAPSSVHDESDEEGDYSGSFDVDRLRHVEQNRPQHVAKNDFSSDTEVVVTSPQSYQRAMSRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG72</accession>
    <name>A0A8K1CG72_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG72"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="126"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="429" mass="49349" checksum="3C6208C3CC0C602F" modified="2022-08-03" version="1">MAIPHPDHEEAHDARMLDDAMARESNNGVVRRRSSSKSSESAEEALRKAGFTRVEGAPEPLPIAMPSFSVKELRAAVPKHCFERSLTTSLYYLVKSIVICAVLFVVGAKFQASEYASSPLAQVVFWPTYWFLQGSHLTGLWILGHECGHHAFSPYKRLNDLVGTILHSGLLTPYYSWQISHRHHHQHVGNMDHDEVFIPMTRPEYESWTDAIEETLEDTPLYNLYRVVGMLVFGWMPGYLIFNATGPAKYQSSSRRSHFDPYSVLFTDKERHLVIWSDVGVGAAFSFLSCLTWTFSLRVMAQLFFIPFMLVNAYMVIITLLQHTDTFVPRFRDDGWTWLHGALCTVDRDFGWFLNDVLHHMPDTHVCHHIFAKIPFYHAEEATEALRPLLGRYYLRDSTSIPVAFWRCFTQCKFVEDDGTVVFCKKHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGY5</accession>
    <name>A0A8K1CGY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGY5"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24138">
        <property type="entry name" value="TtcA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="97"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="3">
        <location>
            <begin position="813"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1082" mass="122124" checksum="328D5344CE442B05" modified="2022-08-03" version="1">MNSRRPGQRRASAEPTASLPICDDLCSQRYSLDFMEEDIVEELRFKDLDHDEDEDQDIRSSVATWDESQTLIQDINANIIGRNRVFDSPYGMRAILYADYTASGRALDFVEDYIREEVMPHYGNTHTTTSITGLQTTCFREEARQIIAQCVNAKISGKTSEDCVLFTGQGTTSAINKIVTALGLMLPLPSNDPNERPIVFVGPFEHHSNILPWRESCAEVVQVPENADGKLDVAFLVEKLQQFASRPLKIGAFSAASNVTGILTDVDHISAVLHMHGALAFWDYATCGPYVKIDMNPVVHGAMRPYVYKDAVFMSGHKFVGGPNSPGILVCKKRLLGNAVPTAPGGGTVFFVTKNDHRYLSNKIEREEGGTPDIIGSIRIGMAFELKQRVNPTNIMKMEAHHFQVVRESLECNPNIVLLGRNDLKKLPIFSFLIRCGERFLHFNFVCALLNDLFGIQSRGGCQCAGPYATRILGITDDLLISFEKAMVDKQIVLRAGFSRISFPYFMPDNEVDYILQALHFVADEGWKFLPFYQFNHKNGAWKHHTRFNKFPNRKWISNFTTRKATLKKSERLSDADLVEHYEENMMHARLLADQIMDGTMVMPGINTFGEIKDHHYDTLRWFTYPSEAYAAIKAGVKPATTAIIAGPVQPGKYHDRDPELAFSQGFAISNYAPRVIPWRDRNLSSDIVEIHNDEREHENVPLTMEELLGTQTNRSADAQSETSESSHEEHPASTDSGSNERAQDEKRPLRSTKDGLAKDTSSTHFDHVHKSTSEIMQKVNSARVFPTPPPSLMKWVGLAVSHWKMIEEGDRLLVALSGGKDSMGLLHVLLHLQKRSPIKFKLACATIDPQTPAYDPSPLKDYVKSLGVPHFYITEDIINRAKRKMNGNSILAYTSRIKRSALYTCCRQNKYNKLVLGHHLDDVAESFFMSATHNGQLRSMRAMYLNEKKDVTVIRPLAYAREHLLKQFAIDARLPVINENMPVGFEEPKERQRVKRMLSQEENLFPGMFGSLRRALHPLMSGEHETHKSSRDSIIDLGKIPSAMHDDAQEQLDIKDMSKGELRKRDKMRDAVRGLLRSIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH89</accession>
    <name>A0A8K1CH89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH89"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="384" mass="42306" checksum="59C360967F3BABE9" modified="2022-08-03" version="1">MPFKLAHPERRVNATASATSSAAQQYYAGDQAATYTTESNALIQRELTVYTLELLQVLGSFRANDDASLFTLLDLGCGSGLSTAAAAEWLGEKGTDALTIGFDISASMLSLTNGKQPDENDVRGNVLSTFYCGNAAQRFPMRPGAFNAAIGISMLQWLSNEGLQTCFSSLFKSLQTSPGAVAVFQIYPTSLEQVNAMEELAVEAGFAYAEVFITFPRSTASRKWYLALKKEPHPPAGDMTKRDASLCSFACRHFRRCAWHLLADQQGEAVGSAAALRARLGKEHVKEAWHIWRKYRRSLEFQAKLTAEDGAKPTLHAKALRSLELRPNEKAIGEALQTYFMSWMDPSKVTFNDMMERMEEVVNVMHKAFSASVAQDRAVQTPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHM5</accession>
    <name>A0A8K1CHM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002503</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75276at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="392"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="814"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1863"/>
            <end position="1977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1521"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1661"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2040" mass="226776" checksum="AFA9F481A2E2A41D" modified="2022-08-03" version="1">MAVSGVGATAFTPLLAPSATLKRHPTALQGLQTDPPAITALRRQLLLSAIAKTPRLRNDLDLVVILQYLLSVDAFMSVSPQALHYIATECTHLVLRDGDVFCYQEDLIHDSSTALLVHAQEHTYAVAFHKDTLDRVVSKFGLTIERGSLSSTREITSTDLSHLAIFSHFTDSMRNTLLHTASRRVVPRGSTLFGPSFSFDMPTFPLQSFVLVLSGQIDVYWAGDAVIDPQSLQDTSVEEGEAESESSESEEELTTEVTTKDTTTEVNRTRSVLGRTPLYSIRRGHTIGEQSLGLALDDLYDSSSDTRTPLHHLPVRLVSGEDTTEVLLISKELYFDKREQDHVLQCYNSSQTSSFSDWVAKIFAGHPPLERSPLVIQEFMWRIRTDRVLSRTVFQFPPRVLERITQTVIPLHYTNSAPEQLYQSGSELLGVDIVLEGSIRVLGDQESNEETSVYHPGDLFGAIEVMGRRACSCTVYVDPGTTILRVPKVTVDRWLTPVRQSLTFNIGTLFYQHEAFSATYRPSQYQNMTYLNDKRKSLTAMARRISAGAAPHDNEDDERVVLPHADALSAVFSRMGLMTAVPRFLLRELLRHVVIVRKHAGEVIFHENEVCTALVILRHGFLAIYSLENLSTTAEMFYRHPFCQFSSLHHLFTKANIHKSGITEDKSVSPTMTPPLTRHRSAMYGVHLQTLHPPNAFRVGVLKDNNACPATIVAHSDCELLVVDQAIYDELLKKHTGVVDLRSFDYEKNAPSCSNEEGSKQGENATTVVNVSTRAIQLGPRWLTATAPSVALRKHLEVIKLPWLTTSDAKLQLLLRSIKVLTLSPGDRVLRRGDVVGQLLIVLAGSLTLYVRQDQNQARNVLDASQRSVRSLMLERNVTSNYSTTSHQLYTNRDSRGIQHKRAFLKHRVNRMVTTSNAKDAGEVTSKTADPKETKKTSPSMFVHSVLAAVRDAKLQQISVTATDEASSSVNGGVSPKRKTSLTFQSVVSKAHLLHRMDERRRAIDTPPSSSGFDEVSNASKTTRELNNTSSGSILFCHLHPGDVYGEECLTLSVVYCSPHDIFAELDSSAPTSTSNLVQLLSLDRRSYLEVVAKSDEEIEKELQGRASAARAKWQLVERKITRERGSVTTPQSTRLSTIKTPKLFDLLRNILNQRYYVMMRAISEIPVLTDIADTAKQELAAAARFEALERFANAYKDASPSSDVLPRYFIVLNGRIGLYPKTLALNGSGIGSSSMASSFSPSQNTTTATSAVNYASVAHNPELCLQEIVTGQGFGEFEILLPEDASRHHLLAFALEPTKLLSIPGELFVRHWPLIEMIRANIEYLRHEVQFFSRLEVERVSYLYHSIRFSAVYRGTKILEQSQVLPKGELFLIKDGECAIKAKVTVHPSAPGSGGDSADQQLADGPAGQTVTVLATIADVNKGHLFWIDRRSLQFTLQAISAQVTIAQITIDRLRLLLPKTHLFNIEGRCNQLAERFRNQLQLAQQTIVRLMNEKRAAELGQAKPSAYLPLLHYAMQAKPVAPPTTNPATSRLRRRLKKEEPTTKRPVTSAENELIAGKPPAIPYSRFLASRPIDLQSLPVQFETDCLSVEEITATREISNQLQPQLQNPLEHYQLSEAANNQHQSSLMNPAVLRGSFHGTSSPQSGRLPRLSRPLEDVNAKESQTLRVEPVQLVATPPMRPRSTGRKSPSSAKATRRVSEPPLLRLEVTLPGVIRATPPHERELDQPQARLSFPFNQVIANNTRAEREAEDVDEILDLRTLLAAKLQSAMSPLRSIRLKPSQFKMHSLGKYFESPTVSPHRNQQRQAHLAPPMASTGEWRAGRPRVSSVSTSTASAATHIHKVQTITRKQGFLRIVKIPSSITELAALEKQLDDAGRHLKTRFFAIVDNRLLEFPENVRVDENLLQSPAISTIDLTQVHVQEAPVVGTTSEVVLRHSFVLSVSSQQDESIEHLLLTCSSLPERKQWMNALETAALLGETPSWTRSVPSVAHGAPGSPRHRRASMVKLTGSPRSQGAHGIANTNERIEDDVLHVQFRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHX3</accession>
    <name>A0A8K1CHX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005653</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHX3"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="640"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="74"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="673" mass="74434" checksum="B34E2B2594906B7B" modified="2022-08-03" version="1">MEPPQSPTTAFSIVTDTPTGKPLTGTMGLTSAAVADVSSPPRDTVIRMERAESAMDKLPIPKLGISWNNVCFSVKIKDPKTKRIDDKPILKSVSGEALPGELMVLMGPSGAGKSTLLDCIAARNRNCTGSILVNGKAWSKAVAKHSCYVMQDDLFYANITVLEHLTFQARLRMGTRFSPQDREQRVAQIIRELGLTKVINTPIGDVQVKGLSGGQRKRLSFATELLTNPSLLFVDEPTSGLDSFMAETVVMQMRDLARRGRTVIATIHQPSSELFELFDKLFLLVDGSTVYNGRASESIPYFASLGLQCPAYMNPTDYFMKQLVVMDDNPGSKERVHMLVSAWDERAKKSLDNGSALVSSSTTGTSSDFNQPQSQDDDDNSISVEGAKDHAPSIFVQIDVICRRNVLRLVRDVIGFKARIGSTLFITIMIGLIFLQLKRDQKGVQDFTGAIFFIAVNQLFSSANPEFISVPLEIPLIMREHNGGLFNVLTWYFAKNLSELPFQLLFPAIFVLPCYFMVGFGNDAGVFFSFYLIIVLLSSSATGLGYMVSCLAKRVDVAPILGILFILPFLLFGGLFLNSDSTPDYFIWLQRISPIKYGFHGLMRAFWNSVDTIHCASGAKCIFTTGDDVLDLNSVKRGQMWLDCVVLVALNIAFRLLGGFFLWRRTEKRNQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI68</accession>
    <name>A0A8K1CI68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI68"/>
    <dbReference type="OrthoDB" id="126480at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19327">
        <property type="entry name" value="GOLGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19327:SF0">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="56700" checksum="CDDBDBFF0377FA35" modified="2022-08-03" version="1">MRRHDGDDAERKATRGSLVSIAKVAAEPSEGVGALADEVDALTFATRRSAGRESERPEDGDSHQDAVVKQIKRNFVLEAQSYRTRILEATHAAARARERVDDVQNESVRLKKKCFKLQKQLQERDSRIEMLQEQLDFKFPMLMHETMRGLNQVMEDNQDIEPLRPPSTASIRRSLEQAEIVDERIYEYEKQVAQLYEELATEKQKNEMLTECLHEQKQAKAKLMKACKYAKKEIEAMKNSGMTQLLEDLQSRCRGLEADNTRLNEQIASATTNEGELQSTISEMRSQLMKHELEASSWNDRLRAKDDEIEQLRAQVREQQFALENYQQDYDLVIGRKHSNDSNLSRSDLQDECDKLTRVLQRERTRVEELEEELAAARARSADLTDRKLEAYEHSDVPSDPTVAQGLREVWHEVDQVNTKLSSLQTQLVEFGEPALLGLASHAKISSLAPTDWPASDALACVAKVRSALHQSNVVIDGMQQFVEDSYARALGNNCAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIL3</accession>
    <name>A0A8K1CIL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIL3"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="157"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="312"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="738" mass="83442" checksum="569C9E964FC0C265" modified="2022-08-03" version="1">MASPAPSRPPTRLSVITTAEGGTGSTSTPTTPRTPRRESKDQLARGVRKPVKPSSTASGAASNNGTENTLITAAALSSATSASMEHASDAHSKPKIALSKRWGLIRKEVMPNPGLMKINERVLQIIQTLRKPPEDRSENDIKLLYTWLMNQEKISSLFTTMSEVSAKKLCKEMEFLHLKAGDVVVNQGDKGNTCFILLSGLVSVHVRSADDQKKYHRVTRASLDGTSSRQLVDQGLITFGPKVVSLTPGATFGELCLIEPDSKRSATVLVDESAQVANFIVLTAASYLRMTRSQTIEGTITDHMAFLQHTLLFRKWTKMQLMHLVNSMKLLTVPAGQFITRKGMDADSFYLILRGEAHECLRLVLNENSEVSMDENRGVQHCITVELTYLGKFDVAGEYLAAEKKIVVCPIDIRAVSDVDCLVLSRKLFNLHFGGKDMKPHALRAFNRLRSIGTQREMWRETRLNQALQYPNFRVPITRKLMRLSGNICMTCGRDTHVAGDELCMELTTYRMEDEKRKKLEQQRETRTRSRHRISVRPTQTQVSTAAKRAQQDKNKHLPSLNEDDEDDDSDHLSEEDELETRKNKDDDDTAERMSKRLGLRLVRKQWRAARQAGLLAPAPQRPATTPAESPTTSPHTRLLRITSVTRSMHLSRRRLLEGEQKERTVEIEREIQRIRDAWPYNWKDLETHSDEDEANLPRYEILYRNMPRSPRQTATPASRPDQTPTKLSTTRRPHTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIR1</accession>
    <name>A0A8K1CIR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="437922at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058541">
        <property type="entry name" value="Ig_TPPC8_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058540">
        <property type="entry name" value="Ig_TPPC8_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057651">
        <property type="entry name" value="Ig_TPPC8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24545">
        <property type="entry name" value="Ig_TPPC8_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24546">
        <property type="entry name" value="Ig_TPPC8_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24542">
        <property type="entry name" value="Ig_TPPC8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPPC8 first Ig-like" evidence="3">
        <location>
            <begin position="718"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 third Ig-like" evidence="4">
        <location>
            <begin position="985"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 C-terminal Ig-like" evidence="2">
        <location>
            <begin position="1258"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1394" mass="153692" checksum="7D5F9629D1F3044A" modified="2022-08-03" version="1">MEGMEQWIRETFAPMVLTCTTPEVERLAQKNNVSFADLLNGFSILRNVETPIRSVSHSYTLTDFYFRFLSSTQFGVLPIADSMRLLNQVVLQHPPPVANSVIDLDMPTVCSVDDVPVFLRAIGAANNTEPLSWYREFKRALMDTFRCEEYSMMWQPAAIVLVVSSTDSNPRSCFEQLSSSQNLPPGFLQGLYDPNVPKYYLVVHDVVETDGTTIDPDAILHNLGIPLSTGAVVRINSLPVETPTDTNQSIWTTHPHVRAPLFSDPNSGNYPYLTEYVGGFLANDDLMRIQAFVHEFGLRFVLPALETRIFQLNEVVSAMKKGVKNVFKSWLRKPKDLSARERSSSNTVTYRCDSIEAQTRLLADTAFMVRDYELALQMYRLVRDDYKSDKSTYHCANANEMIALCLLLTKGSPVQMSNALDAALSTYYKVSNAATCRLAVRAAVIAGEIYNTLSHSGLFTDYMDNASAALIRGSTMEQGICSAVLMERAAMCDIQARLPKFRKFGFRMVMAGHVYDSLGHSAHSARCYSLARAIYNASGWFQVEDHINFTLAQQSNRLNDPMASINLFLKLIGTGRNSASQQEALLYEFGMIVKEFLSNDTAVSKATGARSGSVMVKNTSSAAKKLLVRDLCMPELDDKSTVVFAPVNAFGIDREIDGNAAELDSWKELEQVIEKQNQIHRHASQQSESAVSRDAKRETNNVWLSPISSFNVQYRGKKNGQVKKPEQYALGEKIYVEFEMKNALSCAVDVENIHLYGKFEPRDGSEAFDVPESDEPSNDRIAVEHVNLQLLPVSEERVRLAICPRIPGTLRIIGIRWSICGGDVHGEHAFNIPGPLLQDTRANKEARARAPNTTLIADVVGDMPWLGVKVDYDPSDAYVGEIFRWRVSLVNSGSADLGGLQLCCSDLSLCASESEAQMAGYIGANGQVVDLSHIQLKPGESRDLVVWAKSSRAGKQQAQLIFRYSRLVSGEDLEKAPSRTVKMKVELNLLRCVDVVYSIEPSYAASGEYVLGLSVTNRRRDSQNSDSDVQLERLKCISKTWDILPFSHPPQVAGVRTSYHLSFQESSTSFFRVVPKSATSLDSQHSSVELGSAATGVRSKLEGLPLEQLLCLDHALELVRNADAAAAEGLGGDRPGGIRSIQSVRRENKALKNTSESNAGDTKRDPQPTSKDALLHSPDIDAHLVLVWSASKTISSRQPQQMNGVGAPFAIGQTNLTSIRVRSPLKLTSCPLTITLAYKDSVTLRRVPSPHSTSSLALAELDVAMTIRNDSTLISNPIDFIVEMLHPEESKPMPIAKHGSVGPPPAISLAPSPHFFWTGLTKKKVSQFQPNATVVVQLKACFMAAGIYDLNRFRFLVSPSPSADGPSPTPPPAVFVFPVEYLVNVQPPVDTGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIT7</accession>
    <name>A0A8K1CIT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIT7"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="76"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="458" mass="52375" checksum="05440DB1EAA19E32" modified="2022-08-03" version="1">MDQWKQVQTESRELFMILRDQYTRHGAQYIQDLFPCVERLIHMTSEQAQLPDTTETRSIRWAYPLICRSLWAREMTVVMRGYVECAEWRALWRNQRREYLCLCDGATLYFFTSKMQCEEYLFELTRDVDDEDSKESETHKKILKENAPQQCIELGRNKWSIRKGEKSIDPDDAPDMRHAFALFDAQGKLKLILDVASENEANQWLGAIKSELNRSQLYAKIDQREYSISDNGTGGLKPSIAFANGSSIQDVEIPLRWLHRYIDELSSGSATRGRRTSSTMTQAKKDVRRDRLCLNGTLLTAMSLEDIVQALLIQIMSATKNAIAEIEAFQFAHLLLISSSRTQGGGDILDAIQLIFPGSHFCVCPDANVMEPILLDLSYDTNQTGDRKLVAEIRICMGYRILHAGQDDEGVVEMVKTDGRAIAQVQGQYYRRLVCDQDEWNCLEGVIQLQVIAQGEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ40</accession>
    <name>A0A8K1CJ40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">KHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011389</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ40"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061118">
        <property type="term" value="P:regulation of positive chemotaxis to cAMP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17073">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001763">
        <property type="entry name" value="Ras family gtpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036572">
        <property type="entry name" value="Doublecortin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021789">
        <property type="entry name" value="KHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11834">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89837">
        <property type="entry name" value="Doublecortin (DC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51490">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KHA" evidence="7">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="30369" checksum="56BB179E77907BE2" modified="2022-08-03" version="1">MSDKRLFIYKNEAGSEGKVMNLKARDTLTKLKKGASKKLGIKAKRVFLASGAEIQDVDELQNNDTLYISQGEGFYKAVGNSHGQETFHVSVLGSGGVGKSALTLRFVRDYFVKDWDPTIEDAYRKALTVDEGLCMLEILDTAGQDDFESLRGQWMMDKDGYVFVYSMDSRLSLHELQSFFDLHLQINESRRPLPPIILVANKKDIVEQDPSRCQVTTEEGRRIAHSYNATYIETSALTGVNVNAVFENFVREVRKRKVPKPKKSSCQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ67</accession>
    <name>A0A8K1CJ67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ67"/>
    <dbReference type="OrthoDB" id="168421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="22467" checksum="497BE5AB3FCA00BC" modified="2022-08-03" version="1">MAVVASRTELTLTWTPPTSPDSVCDLIGNKRKHIDEAIEMEKANTRKVDDVHDEKSDSDATSITPLSTSEQLEYLTVNEYKWPSLNRKRQRMSEDERKARHREVQRQFMQRKLAKLDEMRHLVVVLEKQYLLLQLSQERARLEHENDYLSRQAAATPPHWSLPESQPRAPAPAQTQTSAALPWDEILEAVSEANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ86</accession>
    <name>A0A8K1CJ86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ86"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="435" mass="47533" checksum="BE54F14112099EC9" modified="2022-08-03" version="1">MRVTAISPQAGEVSGGYEIRISGRGFWSSDDLTVRFVPLTEGRLPRGNLAVFDEHTGDVVCRVPKFSLSGEFAVEVAVDGKHFTSDGHRFEAFKNPVVENISLDDAQFDGGDELTIAVAGDIPVCCTQPMLRLIQDAAQESVTRVEKTTSFLVTGSGERGVADNELSTISFVMPAIEPCDDIMRFTMEISYNNGLQFVPIISPGESDSSEDYKPHVISFHNARVIRCRPNSFLSRALPQVFTITIHHLLGDHLDRVSVGLEVTELNISDPEAEARVDVSLPIVKLGGDSITSEETINLEDREEVTIFVALDGVHFQMDSSLRFIYCIAPEIHEISPVEAEPGTKMLIRADRFASSGAAWVRLTASSLGISHIVPVEVVENQQTAEFVLPPLPIPSEDTVFVAFSIDGQQFGIRPGATDGDSTSRESALSFRYRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJQ2</accession>
    <name>A0A8K1CJQ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002418</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJQ2"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1190:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="169"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="532"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="607"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="667" mass="76145" checksum="81FBF4676DB2E533" modified="2022-08-03" version="1">MVVYNFKKIQTVPSANDFIDIVLTRTQRKTPTVIHPTYAISRIRAFYMRKVKFTQQTCQEKLSQIIDDFPRLDDLHPFYADLINILYDRDHYKLALGQVNTARALIDNIAKDYVRMIKYGDTLYRCKQLKRAALGRMCTLLKKQKASLEYLEEVRKHLSRLPSIDPNTRTLLVTGFPNVGKSSFMNKVTRADVDVQPYAFTTKALYVGHLDYKYLRWQVIDTPGILDHPLEDRNTIEMQAVTALAHLQASILFFMDISEQCGFTIEQQLSLFSNIRPLFANKPLIFVANKVDQVKFEALSADHQQMINEAVETTNAKFFTMSNHSEENVSDVKNYACDELLKHRVNTKVKGNKVADVLNRLSVAVPVARDDVKRELSIPASVLESRKNGGSTATRVLQKELMNANGGAGVYAMDFREHYKGMLKDDNWVFDSIPEIWNGKNIADFVDADILKKLDALEQEEDEAMANAPMDMEDDDDVSDLDDEQKDKLTRIREKKAIIVAEHRMNKNKNRSSLPRKALAKMRTLTQTKKELEELGVDTSHMKHAEAVVAKRAADDESRGRKRGRDEMDDDVDMEDVDMDEKPGARARSKSALRSKSRNRSQSLVAPRDESGFANEEAVKDARRVMRLAQRKPNKRARAGEADRHATPKLAKWQNSGKRKNGTTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJS1</accession>
    <name>A0A8K1CJS1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJS1"/>
    <dbReference type="OrthoDB" id="93166at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="26511" checksum="99B17F37C6DCCFCB" modified="2022-08-03" version="1">MTGIMLQRLNSVEMMRVLPEDAASHMHSPSFKAPPLCPKLMEPARLSKGADAMHRLENIRCIEISHVVERENHRYYVINIYMQHGQSRIPTNQNHEMVDHMTAQIQPDFQVEKRFSDFDKLYKQMWDAVHRPHGMYCNYCDSFMYNLLFTRAKPSMMTKVFCSPETRIKVLNKFLHNVMIQVRSKWHRCRTMCYGHEQVPCMIRDFLFEDHESPLSPRSSLLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJU1</accession>
    <name>A0A8K1CJU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJU1"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460616" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="4">
        <location>
            <begin position="24"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="139"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="45528" checksum="1619FB819EC53020" modified="2022-08-03" version="1">MFGAKSFGVVVVAALGAVALSSAEEPAVPNAVQIAQLEADWVKTLHQVEDAISDFAKKHNLPVNDPLFPWLPSGDQTPAPSSTPPAPTSSTPLPTADQGQNPGQGQNPGQGNPGKPKCTIKVTDEHKVDVSCPKTDRVRFIGLGDWGEKFIAPYVLAVRDGILKEAATGNYDFILAAGDNFYDNGVTNTTDTLWRTTWLDRWQIGSNLTLPWLSFMGNHDWNGNALSQVEFSKSQLPGAQYWIMPSKYYSIDTTVSTGKKFKIAIVDTQTINTTAEFDWVAKEYTDPTAEFVLAAGHHHIYSAAGRGDNKNAPIVKLNQLVQSSDKVKAYLCGHEHDMQFMRAANKDYFMFGGGGRTMNEGEVGPGTAADVIYFKKKYGYAIFDLQVGTRTMTVTYHVFDNQGKEIDTPKFVRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJV9</accession>
    <name>A0A8K1CJV9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJV9"/>
    <dbReference type="OrthoDB" id="160172at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="221"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="518" mass="56117" checksum="3934EE422D60C09B" modified="2022-08-03" version="1">MTAAAEPSTCYPPVVILGTSAKPQACAGLPITSSHVLVHSQCAKAYEQLTSAFLMVLDDDDDGSNDEETRLARTDVTKIEAVPLQGGKTIHIATLKTPLQATTTLTLPLRTSYPVPLQNDTEATLISVDLATFTIGRVDSVVYVDSSLCDQPVCLLPADIDSRDVNQQSKHWSFLLKHNPNQADGYRLLGLGGSSVTNQDGIWGFSWLPQQLSSSSFADLGVSGVKTVTVTNTEAVPWGTSYMNEDIQYIVELRSVKSGATVCLGSLIASRWVLTAANCQRSNIKLKWAGLNAMRAPSFSKDIEIIEVGRTIAHPSYRALRTINNGREQITYYNDVLLVELKRATTRKPIKLLTETSNAPKEIKQAINATVFAYIMVNNSDALLPMTLPLIYGRDFCNGLVGINMSVTDEEIVCVGGMPWKETCFTMFAGGGNPLVLLRNTQHQRLLAIGSAGVACRPGQLYSAYTRVTGSLPFINKYIHSSTPTTSKPNDASPPPVTRTPPPTTKKPSKVANFPPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKW9</accession>
    <name>A0A8K1CKW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKW9"/>
    <dbReference type="OrthoDB" id="303107at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031213">
        <property type="term" value="C:RSF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056522">
        <property type="entry name" value="KIAA2026_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028938">
        <property type="entry name" value="Rsf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296:SF3">
        <property type="entry name" value="DIKAR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296">
        <property type="entry name" value="REMODELING AND SPACING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23450">
        <property type="entry name" value="KIAA2026_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uncharacterized bromodomain-containing protein 10 helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="WHIM1" evidence="4">
        <location>
            <begin position="309"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="500"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="500"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="67105" checksum="E350A6CA74C819FF" modified="2022-08-03" version="1">MAKPKQTTTRARQPAKTGEAAQRKRKGAAGEDGAKKRARKVEAGNDEAPETNDAHAVDVDNDASHANEGVADADPAEDHGAEMNGHQHTDEEVVATPTKSKPKKTKSTKQPAKSKPAAAPKKRKTRTLEDKQRENAPMNKAFYVETGEDWHATNVDFDELTELRAMWQLPAAAHVLWLLQQPLTLRACNTLLEYEAALLSPESSTLLEDVFTKLLLKKSERDCLAPGIGLKYEWWNKQLREYYLALYDKWYALLRKAGDKVPVTVSFLESSESEEDLSDSERDVELSDDEWLALDILKSRLEGLGAECPLQHQSFGELTVQQRCKILLNLCEAVVDDPANTDYIRQMEEDDLRNEPVGRDRAGNWFYFFPQFYQERRMYRVDVKTQEWTLWAKGDDAFRQMLTAMRAIRGRKLGGEQELIDHLEAIVEQIEEEAEVRAKQLEKATRKAILEAIPRKRSLRIQVKQIEQLEKQQEEVEAKKVMSQEEIAEMKRAEFLRKVEQDAERESREREREARRQAQEEQEREAAQAEREMRRLRRLEKEQHEEVLQQKLEEERKRQEEARKLRAMQRQGDELEFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLZ6</accession>
    <name>A0A8K1CLZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLZ6"/>
    <dbReference type="OrthoDB" id="204376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="27"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="28"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="168"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="201"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="235"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="367"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="571"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="637"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="670"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="769"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="802"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="835"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="941"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="975"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1008"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1041"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1074"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1107"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1140"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1174"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1207"/>
            <end position="1239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1269" mass="132518" checksum="C077DA4E3A9BD6A3" modified="2022-08-03" version="1">MSAADKEEQTLAALLRQKLTLQGAEEEEAAAAENDASPLHEAVMNGDLARVKELVAATPESVLVKNKLEATPLHIACVEGPLEIVEALVDAGADLEAIESFQLTPLFVALVSNQLEIAKYLHSKGASVDGRVDRVGITPLHYVAGEGELSLVEWLVENGADVNAARQSNGPPVLAAAAKGHLAIVKYLVEKGANAAAQNLEGSTVLHAAAAKGSKDVVAYFLENKFVDVNAATAGGITPLIAALQREDASEDVVKLLLDAGANAKTEAVLDKATPLHCATQTGNVALAQLLLDAGADVNAQTTMQATPLYLASFFGHLELVKFLVEKGADVNLQTTEHATALYAAAQNGHGTIVEFLITRDTTWKNAQQPALLMPAQAGHLEAVKALVAHGADPNSADERGVSALILALSFDHVEVAKFLLENGADPKVGAGVKGSTCLHTAVSHQQLELVQLLLAKGANVNAQMTDGFSPLHLAAQLGAVEIFNELLKKGADATLTAAANTFLAAHYAAQLGMLEMLEALEKAGQLPNWELPTTKDGLSLLYLSAANGHENVVRHIISKKGIEIEGHAATGATPLYVACQQGNVGAVKLLAEAGASVATPMADRSTPLHVASQNGHTDVVEYLLSKGADAKAVMNGNATPLYLAAQQGHFEILKLLHGKGADVNAAMTDGSTPVLIAADKGNEEIVSFLCEHGANVAMAMANGMTPLYAAAAKEQFKIVEILLDAAKPGALSSAEINTLLIAGSDGGRIELMQKLLDLGADVNATNQSRFTPLFRACGSGHLDAVKFLVERGADKEAKGVNEMTCLHIALSLRQSEIVKYLIDQGANAQAQAVDGSTALHVVAEAGDVELFGLLLSKGADAYAATSENSLTPVHIAVQHGHLALLVKLQKMGLLTDLEAPTKEGGVTLLYWAIAHKQTEIVRFLLSQKDKKVNVNAAAQNGSTPLFVAAQVGDLEVVRLLLGAGAAAKIMLENDQSSALHVAAQGGQVEIVRLLVENGADVHDTMGNKATPLYLAAQQGHLDVVKFLVSQGASVDPAMQDQSTPLLVAAQNGHTGVVKYLHENGANPATHTASNATAIYLAAQRGHVEIVKYLLTLDVPVDSSMKDGSTALMVAAQNGHFELVEALCAKGADQTAKMAVGATALYLAAQNGQTSVVELLLAHGKVDKEATMSDGSTALHIAVQNGHVEVVQLLLAHGASANATMTDGMTPLHIAASCGYVPIVMMLLVARANIEAKDDNRMTPIDYAAMGRHNDTVEVLMANGAILRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM97</accession>
    <name>A0A8K1CM97_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003879</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM97"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="31214" checksum="E7EC7331113A1E1C" modified="2022-08-03" version="1">MAAAYELSKPLPSGARIPTVGLGVFQATNPHEAYEAVLAALKVGYRHIDTARDYENEEEVGRAVRDSGIPREEVFITSKLFPTDWGYDRAIKCVKESNERIGLGYVDLFLLHAPGDRTKRAETWRALEDLQQQGVVRDIGVSNFGADHLEKLAETSRVKPAVNQIEVHPWLLRPEVVKYCEEHGIHIQAYSPLAKAKRLTDQAVLDIAKEVNATPGQVCIAWSMAKNFITLPKSFNPTRQKENLDSIYVKLTPQQVARLDALDEYLVLSWDPIKNEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMC6</accession>
    <name>A0A8K1CMC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMC6"/>
    <dbReference type="OrthoDB" id="70760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033749">
        <property type="term" value="F:histone H4R3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106140">
        <property type="term" value="F:P-TEFb complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF22">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452650" description="JmjC domain-containing protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="4">
        <location>
            <begin position="411"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="627" mass="70666" checksum="80F84586D0BA2DC4" modified="2022-08-03" version="1">MSMRSFVYDMFGVLLLLGSYGAATSTVIVSGAITPSPSVHDVNAWAFETFLDVRDPNGEISRVEFRQHCCDSLQDVTSAFCHEFRIPPQDCGRLGEFLLIEGPKNRTECQCQPQMKAKKLGTLSVNIFRADVDRTESIRLSVHTGDLEMLETRVESICTRFHLSPEACDDIQGFIEKKVLELEITEAKASLNLLASAVRGNEVVVTAMATMQSAIAHLERVNAELRRQLIQKANAHSRLYWQSIEKKHKMERDLRRCTRTQSTNTSLPRQSPGRTVRLSLSSSPDGSGKPQVKVARSFLPYTMRIPRVHIANFSYAQYLEAARHSEPIILQGFSTTQGRPGLPSWSLEHIRNVCGNFTVPLKKVPSSTDRKKTNEVVGRVWAGIEQVTEAPLHEFLRDFTSPESLAGWPSSYADLYLHDVSIPSFCPELLENFVVPRFFASDKLQLLAKSTQKDYWPSLFIGGEATASAMHADWAKTAAWMGLLAGRKHWLIAKPSAKAALYERIPTASAPAEGRFRADLLGKHSDMEKLWRDDEVYEDVLEAGEVLFIPADCPHQVKNLEKTIAVAANFVDDANLPAFTEYLEHWRDFTVQERYRVNGEMLKTLQASSPVEEPRDLSFYEFKTQWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN36</accession>
    <name>A0A8K1CN36_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN36"/>
    <dbReference type="OrthoDB" id="99548at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="724" mass="82495" checksum="2265CD15168288F2" modified="2022-08-03" version="1">MMMRGLVCDFVLDDGCEHPEHRLFAAEYKRSNRSRAAKIVRCFPHCCPDHRGRSYCGSPLHVKITLDTDEGEPTLEEQSRLSGDLFVFGRFEEEEPSADDESLQYGQRIHRDEIVERDLAPHAVIWHPAEEIVGGGQELSSTNAESKRVFTLTGSGNGPFHWEYNWNSGTSKRARATLHHFRVYVFAPVAQRGRRATAKNTMWEVVGIATSPTFVFTVYRKHHDIANRMVYDMMEDEEELHEDEVEFEDEEETDDPMESLETDTQFVSSPVVDQGVLWHIQQRATVRRSTSFAILIRFGQMTDASWLSQHRNMMLELLSSYDAAPEHVLLHYVAHCVPSLVNALSPRICKASTQYPWLQRFSESKWERTTNLFGRVLCYIFTFERWNQLRAIVVAQACAALEDVQMQDVFVQWVASIGEEIDLFLRTQGTSLDAFSDDIVTAVLTEYQSDEDGDHDEDVQQMRQLLRNTSALGLYSFRDHLRRLRTHEQVSTPPRIDREDDENPPKWQGKWICRRISSSPCVKASIRRHSWPVKASDDANSSAQGTPGLGLLPVMLTSMVAFGLELQYETKDKEDADQRLEIRGLASPVGDIIARIRLDGIYQSLEDVVSPEWFAVFQMINGDDVTAWTARGKTSDEGFEVDLVSSVAGRQWVFAFHTEGVGDSPHRSSSAFVLSRQQQLRVSVRLDEALEASISSNNGAKEAHETQWEPRTRFAMSYCKVSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN41</accession>
    <name>A0A8K1CN41_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN41"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000116">
        <property type="entry name" value="Leucine-rich repeat-containing protein 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="137"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="664"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="723"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="740"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="763"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="826" mass="91829" checksum="ED661CDD643F27D6" modified="2022-08-03" version="1">MERRNGLSLREAMRRNAQQKRQQEMQGSASGGAGGGAGQGLARAYRQARQTGQLNISTRNLKDFPMEILRLHELVEADEKSWECLALQKADLSYNEIPMLPPQINKLQYLTSLKLRHNQLVEIPEELFELTKLTSLDLSNNRIEGDISERLSDLVNLRELALEGNKITGLPDSLGQLENLESLKVEENLLQFLPENIGQLQRLHTLALHSNQLTELPASFSRLTNITVLDIKKNALVTLGTAIQQLNRLKFLDVRQNRLQEFPIMPSGNPPLDQLMLGYNFLTVINEESILGVKDTLTVLDLRDNKLSALPDRFAHLYRLKTLDLSNNDLSDLPPGLGYLKYLNHIVIDGNPLRSIRRSIISAGTQALKKYLRTRGSPPEGVEALEEEFDEFALRDKQQQEEKQGGFVMDGNAEASSEYEYLFRDAASSGALQMVDMRLQSLPDQVIGTGKYKLAETLIQLNVSKNRIGSLPKAIGELFALQTLIAEECGLTSIDSSITMLNQLQHLRLRKNFLTADAVNAFFEFGEQANCRHSLKELDLRNNYLTEVPSRCQVLFTVDTLLLSYNRIQTLEGFPWASMKRLSVISLSDNQLESLGTVYELPLLTSLSVENNNLRQIPAELGNCENLRALYIVGNPQRSVRLNIVNEGTESILKYLRNRLPSPAIPSPAKPGFGESTVGPRTHRFTSNPEPPSCSFASPNPADYKRARRSSAVSPGAHVDMRQISFPPDNNTVAPPPAPVNRAAINRPEPTVSTPAPAPVAAPPAAAAPAPSGSDEVLKGYDTRIKTLEGELDDFAISQAKRFALKKELAKVRSLRIRHVRAAEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNC0</accession>
    <name>A0A8K1CNC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNC0"/>
    <dbReference type="OrthoDB" id="167847at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="31297" checksum="B6B45DCD24607486" modified="2022-08-03" version="1">MSLRAASQTTCVLRIDRRRSVKRPWHRLMDEIVVIHALTFVSDLERDVYDYRFALRACSRASQPSVAFPTTLVIARNDSAVHIGTFTVIETSRQPPQELPSEPVGEFLFVLPVVVMITIAFFAWVALKRDTRPANTSALLEVRHRSQTGIPSLSIDEDVDADYPECISVTSNEVSDVDKSLLMPDLPSYNDEVGWRQFFDAQIYRRPEPTPHTRPRPLLTRPSAGLRPRSRPTPAPQASTTQNHVSPTTKSPREQPKTAKSEVKTPSADEFGEFWQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPB9</accession>
    <name>A0A8K1CPB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014906</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000023">
        <property type="protein sequence ID" value="TMW66558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPB9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38056" checksum="7A332E44F854A6AE" modified="2022-08-03" version="1">MRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIEMNCLDAEEEHDFQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVILAYALARATHVWGPDATEYKPERWVDETTGKVRNESAFKFFSFNAGPRICLGMNLAMLELKLVLTSLLTRYQLDLVPGQTITYDNALTLAVKGELFANVNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPK2</accession>
    <name>A0A8K1CPK2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPK2"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000019">
        <property type="entry name" value="DNA excision repair protein ERCC-6-like 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="456"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="867"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="368"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1067"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1150"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1077"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1091"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1162"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1179"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1207"/>
            <end position="1216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1225" mass="137336" checksum="D654622146904F32" modified="2022-08-03" version="1">MEGALFGKVRFPRFYCALHLAITMAELLSSSDDESLVGENASKMAFANVRASPKKRNEGVAAKSAPETASSSRSNASSPKRRTTRRGEPDEELFESLFLPEKTALMAKKREKEVLADFEPWTKSPPSDTMSQASAINVETRPRVTKKPVISARAMLMKFLPSNNTTPPSLLQTTQSSSPSQAASKRQAPESNQEEGSWRKRAKPSASELIAKKYGLLPSSMTQQTTQEEKTTMVPVESQEPEELREESVKKPSPATKRSTWNALSHDAERAEADTDNVQYVSPFNDRRGSFTNMRQRRQRGAGIDKNVIYNDEGVEGVVNRPQHVIGSKIAEKLGENDGDGWLSDAQDLDSDDEATAHAILDKKKLAGSAVSGDSKTRRTASTGRRSKRPRSGSLSDDEDEDVNEIDRWPMLPSPEVSLDPLVLKSPIEGGEDLTVCANINSYLFSYQREGAQFLFNAYAQHTGAILGDEMGLGKTIQVIALLSAILKKQGDYRDKESWRQLRTERRARRSENGATFSENDGPNPLLIVVPASLLHNWESELHVWMSCATVILHGKPEERERLLDQIERGEHEVVICSYDILKITLDRIRRTPWDAVVFDEMHCLKNPESKLTQAVKNIPCKRKLGLTGTLMQNNEKELHCLIDTIAPGVLGSWQQFRSYYGDDIKYGRKKSAAPEAVERSRKKEKKLRQVLVPYYLRREKEINPSFQEVKKRDQVVFCDLTPYQLAAYERILEMPEFELLRRGEELCDCGRDSARKRKECCYQTPASMGTNQRALLWERFHSNGEACNSCPNCMGLVCMAQLLKLSNHMELLKVNPHDPPELQEYQAQFAATALGEDSDAVGGVNQVTTFQEMRDIGSKTCGKMVVLEKLLAVWKRKRQKTLLFSRSTRMLDILQLFLISKAVSYLRLDGNTKVEERLQLVNRFNDPESNISVFLISTRAGGLGLNLPTATNVVIFDPSWNPAHDCQAQDRAYRIGQTKDVQVYRLITLGTIEEMIYVRQIYKQQLSDTTLKGVKAPRYFEGVQGDRRQQGELFGIRNLLCWKEGGVLKGIQDSYRRDQDGLVIQETKVDYDQSKKPRTPRKSKPKHVDGEDEEEMVEVAEEMTTGMISPLKPAKPDKTSGGEAEDSGDDIDTQNLLPQGARTLMHEAIIGDEGHGGDLSSDSDEEEAEYVPDKPTRNIPSSASSPVMVETSNTKRASASGATKTPPKDEGEPIRRTLYIPKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPL7</accession>
    <name>A0A8K1CPL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WASH complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPL7"/>
    <dbReference type="OrthoDB" id="268027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015">
        <property type="entry name" value="PROTEIN AD-016-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="49300" checksum="986CB77F58DB47F2" modified="2022-08-03" version="1">MPPSTALVVANGDGDTAARPEEEEVDLPVDLSQLSMIPMPKTLLLVNNFVANTTRFLNHFAHECEERITRVSTNLTRVEIMLAILEAKLNSIPDLTVTESDIDAVDAGDSPATMTPGISIDRDELPSTEPPQGMAPPPPPPPPPPSDFGDGSMPPPPPPPPPGMDSTALVVAPDYALGPGGEAESNAPAILKLKDDPLYAKYFTMRRLGMPDGAIEQKMLMDGVDPSIISMDPEGPSPSGNAAPQAATGPPPLPIVDGNSGPGLPPPPPPGDWQDGQAIPPPFPPPSMPLSPTSSTSSRGHAESLFGDGPPPPPPNLFPGGLPPPPTNPPLPSDDDDSSSDDETVAAAGGGVLKLKDDPAFAKYFAMQKMGLPEGAIRHKLMMDGVTLDILSMDPDGPSPNGGALTMSAPVGGLPPPPLPPSGLPPPPPRPGLPPPPVRRGVHGLTIILALCFGIGHLLYNCEEHAEQVDELYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ03</accession>
    <name>A0A8K1CQ03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spondin-like TSP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5964156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039942">
        <property type="entry name" value="SBSPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044004">
        <property type="entry name" value="TSP1_spondin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20920">
        <property type="entry name" value="RPE-SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20920:SF5">
        <property type="entry name" value="SMB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19028">
        <property type="entry name" value="TSP1_spondin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="29"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="22"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443364" description="Spondin-like TSP1 domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="2431"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="88"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="324"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="513"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="870"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="1070"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="1626"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="1821"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="6">
        <location>
            <begin position="2312"/>
            <end position="2362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2431" mass="266598" checksum="6113B0C9C796C357" modified="2022-08-03" version="1">MRNSRWALAASLAVTRLLSESDATPTFIWPQFSFGSNTNNYGSTTATSTNSYGTTTSTSTSTSTNSYGSTTSNPYGSTSAYGSTKQDCVVGPWSDYSDCDAYSNKQTRTREIVTRPANGGAACPSLSETVVCVKKDCAVGPWCDWGACDDKAGLKSRSRSVTQQAQGGGRACPTLTDTAKCDKVDCAVSDWSDWGVCIGKKRSRTRTVTTPAKYGGTGCPDLEDTKRCTPKDCTVGPWGVWVVDKTVKRRTRSIVEDADGGAPCPPLVEESPCVKVDCVVSDWRWSGECNASNQRKRVRTVVTPAQDGGKECPALTDTVTCGDCQVSNWGDWSKCDDYSGTKSRSRRVVTEPKNGGDACPALLATAPCDKVDCVVGDWSDWSACTNKQKVRTRDVTTPVAYGGKACPSLRETKTCTPKDCVVGPWSDYAVTPDGSKRRRTRKCTQEPDGGEPCPPLYEEVPLEKVDCVVSAWTWAGNCDTYNQRKRTRTVTTPAKNGGKECPALSETVPCQDCQVGAWTAYGDCNPGNGTKTRTRTVMQQPQNGGAACPVLVDSAPCDGVDCVVSDWSPWGVCSVKDKLRRRTRTVTTPAQYSGKKCPTLVDTQNCNPTDCKVGPWSEYQIIGTKKRRTRSVIQDADGGSPCPPLEEEVPCQKVDCAVSQWGAFGECDLKTRVRTRTRTIVTSPQDGGKECPTLIDTTPCPAVDCKVSDWTEYGPCDDYSGKKTRTRTVISKAQYGGASCPDLVDSLVCEKVNCELTEWTEFSRCNSKTKTKTRTRGVITKPKYGGQACGPLKETVDCVPQDCVVGPWSEFSPCEVVVDAYGGYGNAYDPYSSKSSPGKRRRYREVVQQPDGGAKCPALIEEQACKRVDCAVSNWSEWSECSPESRTRTRTRTVTRDAENGGRDCPALTQSQPCKVQVVHCKVSDWTDFSKCDTATKTKKRTRTVLRDPQNGGRACPDFVDTRKCEPDVDCEVSEWSDFGLCNKKTFRRTRTRTVTVARKGNGAKCPALRECQPCTPVNCKVSKWSKYSACDTYSQTKKRTREVVQQPIDGGAACPALVQEVPCKPNVDCVVSDWGEYSACQASAYGDRSVRTRRRTVVVAQSGEGKQCPKLEESVPCAAEDCKVSGWSPYSACDSYTNTRKRTRSVVQEARYGGKACPPLEDVKSCSAVNCGVTPWTDWSECDPVTSKRTRTRSVRVPAAYGGTPCPPLTEERSCAAEQKCLVSEWNEWSVCDAKTPTRIRTREITQAPTYGTYGSYGSYGSYDSCPALTEEEPCEKIDCVVSDWSNWTDCSKDTYMRTRVRTVTQPAVRGGEDCPPDLTEEERCPEVDCVMGNWTEWTECTLTTPTTKRTRPILTEPAYGGQICSRTEEEEDCPPVACTATEWGSWTECTATTPTQSQQRSIIQDGVRGGAGCGDLINTRDCPAIDCQEGTWGDWGACNETSGMKTRTRPVIQEALHGGEECEALEDTQPCDPVNCLVDENWSDWSTCDSTSGKRFKYRSILQPQKYGGLPCDSTVQDKPCDPVNCAMSAWTEWGDCDASTGKRKRSRTILQKPLYGGMECGDEVEEKKCEPVSCVVGEWTPWSVCDGVDPKSRRSRPVVQKPLYDGAACLETEQEVDCPPVTCAVGEWSEWGPCNEDKGVRRRTRSIVTPVQYGGSACPDLFEEKMCDKVNCDVGPWGDYGECDDVTWKKTKKRSITRKPKYGGDECPALENDLVCEPINCELSAWSPWTCNATSGKKTRSRKVLTNPKYGGDACEALTEEQPCDPVDCKLGEWSNWSTCKDTDLTKTRTRPVLQATLYNGKACEPQREEVPCEAVNCELTPWSDWSTCDHSCGKKRRTREVKQRPLRNGMPCGALEELAPCDPIPCKLSDWTPEWSSCDASTGRRYKTRTILQEAKYGAEACEDTKMSKPCDPVDCAVGNWSDWQACDQSTGKKTRTREIVRVDLYGGLACSSLSDDATCDPIPCAVSEFGEWSVCTADTPTQTRRREVTQKALYNGAECLPLEETKPCPPINCVVGEWGPWSDYDAVFGIRKRTRQIIQPAVRGGAPCDTCEQTERTPPVDCQMSAWSDYGSCDHSIGKQTRTRSVVVPARYGGSACEADSQQKTCDPVDCKLSAWSNWGPCNFDTGKKKRTRTVLQEPRYNGVACGPIEEVDDCDAIDCVASDFGPWSSCNDAGVKTRKRSVLVPARYGGCECPTLSEDSTCEPVQCKVTLWSDWTCNDATGKKTRTRTVAVAPKYGAPECPTLKEEAPCDPIDCKMGEWGPYCDCSPTALIKSRNRSVLTPAKYGGVPCLPTYEEVACSVTKVNCAYSAWSSWSKCVNTSGTRFRTRTIVTQPANGGTPCSTFLRDESSCAGLQCTMSAWSDWTTGCDDYGLQKRTRQILTDPYTGISVCPATSETRQCPYSSTSKDYVPPTAYLLTMEAQAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQC2</accession>
    <name>A0A8K1CQC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GATOR1 complex protein NPRL3 C-terminal HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NPR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQC2"/>
    <dbReference type="OrthoDB" id="18648at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="4">
        <location>
            <begin position="529"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="592" mass="65417" checksum="CA110AD4F694D621" modified="2022-08-03" version="1">MTRLLGIALVVDDIHKGCNLAFRYPAPRTTQDHGSSFHKLSAALLAKLFRPKNALCNQSFELVIDDLRFISHPVLVPRRAVVGGSNNAYQTQRGASDANSAGPTHETTMFNVIFALDERHEDPDHDQDDAASVDAQDGLASGGDDQEAHRQRRKRIITAYRNVAAQLANGMLHEELRSGFVTQQVLELLHIRDELIQNERLMASSNGNGNGGNAVNGTSGGGNNSINSSSGSKDNGGSGGGTDSTNASVQVDPQTLIDVSLGKSVLANDLKGVFHGLEESGTAHVVINSWVKLSLTLTDTVSLKLQNLRPYHTLLLLSEEDKILSALPADHSYQLRVLIAAANPLKSFQDLSLETGMPLHQLFRLAAHLVYWGYGRVIDTITMHNIYQVHPNCSLRVQSACALEFRRKFPPHELCEILSSYAGSRRIGEYVKSLSSIKKIEYIHMLIWLLQHDFVIQLHRYVYFMVPSDHDPLSDSFISQQANENALALANRRRLSSSAAPLLGISGNGDALLAKSIQPSNTSTVGFSDQERAYLDKIATTNPVFTLFKRLCVYFHGQYHLEEIMWRENVSRSELRTVLSTYQDIIVCCLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR50</accession>
    <name>A0A8K1CR50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011078</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR50"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437200" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="30"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="45"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="276" mass="30365" checksum="C6F72F3DDE03F2D6" modified="2022-08-03" version="1">MRTIPSSHWLRVMAIASAVLACFITVVSPDPSPPLSFEALEQEDTAHPYFRPSDQVVSGSPTNNVAAYHRSPCPALNALANHGYLPRNGKNLTPAILKKAVMDVYNVDETLGQSFVGRLPPTLTLADLSVHNFVEHDASLVHDDLYFGYDPAVVNATLVKKILARTDPTTQRITKKCLASLRRDRENESAKTNPQYVFGSRQQAIAYAESALVVLAFGDYYKETISVDHARTFLLKEKIPETWTASPVPITLAKMLETGRQILSLVPSQSALASEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRN3</accession>
    <name>A0A8K1CRN3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRN3"/>
    <dbReference type="OrthoDB" id="114149at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="316" mass="36241" checksum="CA3B2B3F2AE13A8E" modified="2022-08-03" version="1">MDAILSRLDPQQLRQFCADAAQQELRDAVDLLFRTLTATKRLEEVQDAALKLRFAVFRDEDALRAQLEELNAIRTPVVTSLDRIMQLQAITEPSRFQKATLDAAIQTKAMMRTPSKERSDAMEELLSKLLAAVDTCCWSSKAERSASMSDLLNLISDYLVSQLSKHKSNITQERLLKLSHGMQREQSKWGVFEKAIPALKTHLYKNFVVLPHQTDKFKARVEKAIEIVGGWEAEGRPVCAISEFMEQMEVLREVMTCQFKAWHPRGDPNVHKLTNLLWWKQCEKTKKAGEKAKKAIANHQFAQRKAKKNKKHKNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSW4</accession>
    <name>A0A8K1CSW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metalloenzyme domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSW4"/>
    <dbReference type="OrthoDB" id="113620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16011">
        <property type="entry name" value="iPGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004456">
        <property type="entry name" value="Pglycerate_mutase_ApgM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00306">
        <property type="entry name" value="apgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31209">
        <property type="entry name" value="COFACTOR-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31209:SF0">
        <property type="entry name" value="METALLOENZYME DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10143">
        <property type="entry name" value="PhosphMutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006392">
        <property type="entry name" value="IPGAM_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="6">
        <location>
            <begin position="14"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="446" mass="48825" checksum="C267860B68BE0674" modified="2022-08-03" version="1">MTTMETTTPRTRAVVFVLIDGLADVSLKQLGNKTTLEAANTPAMDAIARGGLSGLLDPVAPGYACGSDTAHMSIFGYDPFIHYRGRGSFEAMGAGLHMDKGDVAFKCNFATVKKNDSGELIVERRRVDRNFPEWGIDLCSFLNGVHVPECPEIHVATKYATEHRCGIVFKGKGLCDRISGSDPLKDNLPLLRSKPLDDSPEAAYSSKVLNEVSDTIHRELRTHPINVEREKQNLPPANVVLLRGPGERIDVSTFQEVHGMKPFMIAPTCIIAGLGMSLGIELLKVPGATGDYHTNLLNKAEAALQKFETDPTYEFCFLHIKAVDDAGHDKDVAKKIHFIEKADEMLGQLLRGIETRLPNHEVSVILTGDHTTPVLYGDHSFEPVPFAITRAGAALKVLEDKPLPPASALTDQVETFSELAVLHGALGRFSGDQVMKIVKNFREYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT38</accession>
    <name>A0A8K1CT38_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT38"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006626">
        <property type="term" value="P:protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051982">
        <property type="entry name" value="CiliaryAsmbly_MitoImport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984">
        <property type="entry name" value="RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984:SF1">
        <property type="entry name" value="SPAG1 AXONEMAL DYNEIN ASSEMBLY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="410" mass="47740" checksum="B9D57DE19834F5E2" modified="2022-08-03" version="1">MTIPMRYDGTPEVDFFSLHSRKKKRIDVEMLDYGFVQKCEDVDELKGILAMLRSGKEGRYPDLERATEDRILAVLPEKERNKIITMRSGPSRSELKVEQEELKSWTKQIDEKNKALQEHKKASRSIPPVRGQAKTEKTPMNQPLITEVTAEDRKKQAIPAYDFRGWEKYDVEKAIAEVDQSEELSKEQARLQREEREKREKERKKELASLPSYVDLDELSKAEREVYALHEKQKGNECFKANENEEAVLYYTRSMAFDDSNAILYANRAMAHLRLKNFAQAEDDCTRAILLDANYCKAWTRRGMTRFRRGKYAGAIEDFQESLRLDPTSKEVKKLLSKTRSKWKEVDGTIQNNQASNDMSTSEPPAPQSESKPFKRFEIIEDDEESDEDDDDKDVPTPSKPFQRFEILEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT53</accession>
    <name>A0A8K1CT53_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007828</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT53"/>
    <dbReference type="OrthoDB" id="283575at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007173">
        <property type="term" value="P:epidermal growth factor receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045840">
        <property type="term" value="P:positive regulation of mitotic nuclear division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10740:SF14">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10740">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441284" description="EGF-like domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="31782" checksum="6570FAF69327DAFD" modified="2022-08-03" version="1">MRSMLTRGLVLVVAALAVGVHADLGKECNSNYDCPEGAWCVAGDSEKAVQRCVAGTPCGGATLGSCPGDEVSGQLACIWRPDAEVCSKTPGGCTEIDNKLGIYKCISLDRCDLYFGDSQCSGSCNVNGKQCNGRGSCQLTSESGELPTFKCACENGWNGTRCDNVVDDSCIVDVGQCGDHGSCVKNACECKNGYTGVQCEIPPKSSSSGSGSSTISTSPSPTTKDSSNATATPASQEDKKDGGSNTLVIIIVVIVAVLVLAAAIFVVIARKRRQQQEADGSGFSRVDSANGDAILGGGPPTPKGRIVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTM5</accession>
    <name>A0A8K1CTM5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTM5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="336" mass="39034" checksum="2394807C222EBC3D" modified="2022-08-03" version="1">MPSMERVTRWTLDAVFDRHYPVEQRIYVRMYADGTIAGVVEVDPATEHLDPVVYGGPAGFQYYLYDGTFQWDKKDPTRCELSFMLLRHATRLRIGQPMFCTAYVSTAPPAETETRDRFFNSLRLSTSFDHMPMLHDLDVPRRVRFKAVQHEQIEIPPLVACILPGRYDLHGFSVSADGLLYRCAMVLMINADGTATGESNERIHDDRRHSLVVGTWTESVVRYHLVNPETNKQHSYTYVVRPFIWGFRGSWFLESDLERRQKSQHGQVELTAMRSIRVWSPEANRVYPRVFRDVVRLCVHGTIQTKSEIRFVLPSGVWINVFTFCRFDDVFEDPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTP5</accession>
    <name>A0A8K1CTP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTP5"/>
    <dbReference type="OrthoDB" id="167134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="48531" checksum="1E5E3CECB11C43F0" modified="2022-08-03" version="1">MTVTLFCTVVGVGSVFPVDIDISRTVGHLKDKVKEKNPNSIGCDAALLKLYLAREGDTWLNSRDEDIKALKKGEIPDRIKSLMQEELLLDETWDLNDDAYFGNNLERVKGDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLESESPQDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNRLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKVEIFVKVLDKQCKDRVFSRLKEGSDQTDDPLVMKTFVHVESPETFCFCLRWKHEDNDARWRSFLSMVPAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUE0</accession>
    <name>A0A8K1CUE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001870</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUE0"/>
    <dbReference type="OrthoDB" id="2018507at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="300"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="487"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="545" mass="59469" checksum="DD49079E07108944" modified="2022-08-03" version="1">MGNVQQYIGKRVEVGQYQVEVVKYIGEGGSSFIFLVKDVQRESARPMVLKRLVAENDAAYVWIQREIEMHQRFRHPQVVEFYASQSVRKGRTEREVFILMEYCPLGHLHENLTKMGEKRFKEKDLLRLFRSLCVPVNLLHHNDPPIAHRDLKLENFLMAPNGVYKLCDFGSCVEGPQSLKTKEDRVRETEHVLKRTTAMYRSPELADVDGTAMFGSGELTEAVDIWAMGCVLYTLAFFKPPFPPEGLRTERYTIPKESKFSADLHQLIARMLQADVERRATMDHVIECIDALMGDRPLPKNLGAASPRKAPPASAAPKKPATASGPSSRENSSGAAGGVKKTTEARKESVPAQKPASDLLEIDFNPTITAPPPLKTASSGSDPFGAGAGWTNAAPAGGFADFASFPASPSKFGAMTTPMPTPVPSGSSSFDAFGFPASPVKTTPPQQQQQHYPTGMTQPQGYGFGAAPAPPAAPVDPFEGLGGLGGTASAPHAAYPRGPGQPPHQIYQQGFQGMPQQQQPMWGQQQQQQPMWGHNGGNPGYPRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUG4</accession>
    <name>A0A8K1CUG4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001017</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUG4"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="227"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="227"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="230"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="401" mass="44967" checksum="4CE53C0EC618A014" modified="2022-08-03" version="1">MSVFHRMFGSGNQSNNESSLLVPPLHEMTPMVPPPPPRGHLSTPQHAHMRQYHELPRLQVPPLSLVQPQQPQQPQLHWKIQGPAAPVPPQQQQQPVSRMRMMANFFTTGNTAPPQPPSPPPPTSNVLPSFGEILARTKQLYINPAPVSDETPMENIHMDNAIPEGQPVEMMETMEQPTFQPTYAAARYSLQPPLSIQVNTIMDDVDTAMDMPSSPSGSMSPTSQSGKSSKRRERWTEDEHARFMEGLNRYGRKWKKIQAFVKTKTAVQVRTHAYGYFAKLLRNMPEDDAAWELAEEMSSLPGAVLKGPSSGKRRSEPKTDEAGMEVLRRFVFSKKKTDMQPKTENAASTEPSQLSAPAFNQGQNQPPMQYPAQVWGSTENWNAMESQASSVMLDLKRQRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUY2</accession>
    <name>A0A8K1CUY2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUY2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="738" mass="83096" checksum="A005E4E930490C2C" modified="2022-08-03" version="1">MGNQRSRLERQEEGPRRRGDSQRVLKKVDARKTVFAWTAELPGCCVRLGVDDDVRSIVKSYEWVEFDFSGGNGDLQELQKRLKAARAASISWSALSCCQGFGGHEDPFFWKLVFNGYGSKSWRDPKVTDTKHFFKFSEFPRYRLVFSDSLPMDNFQSLCRLFFDNREDRRMLSPLRSNLRRLAPFILPERVDRDIQVSIQVPYSNPHEFVPGLTSLLESIEADVAAQTVEASGTGREPHFRVHEVGFDTLKLENDDQVSAIISFLKTAAVEIPHLKCELGSGLSSDIIARFCFAACNVGAFKTRATVQELTLTCASMSDRVICAICSVLPHTRSLRGLGLQFHPLQVVDDTASLDHLWYWLDYALRQPEANESSCRHLRLRYLSATAERLEFLRQIGGMTHQRSVQLREGTEIREQPSITASVLMPIRETGSGEVCEWVMQAKSTPDSWVCIITPGFGRGWVKSEDIIDEKAESEPSTPCLTALSFTRSYNGSVSCEAAVLIELLQRYGQETRYLRVSNVPTTDDQIHSILQATPRLESFRSDHDASFWSAENVRKLELRQPLALRELAIRSTGALPSQEAFDGPLAKLTTLEIWGEPSSPFAIEPPSTPCEELGGILLLNRRIQFLHYLDRSVPRDIEYVTTRAKSRSALGIRDGEDSAMALAPMPLGCRVAFCSVIKELVERGTIADHCDPHVMSRIFEFASVQVPRLVWVETMANRATLAQMESVGPFHARSRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVE9</accession>
    <name>A0A8K1CVE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001497</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVE9"/>
    <dbReference type="OrthoDB" id="27095at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477509" description="ER membrane protein complex subunit 7 beta-sandwich domain-containing protein" evidence="9">
        <location>
            <begin position="25"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="10">
        <location>
            <begin position="36"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="201" mass="22127" checksum="417FA486A3D4C7B0" modified="2022-08-03" version="1">MTMLRVVQAALVALAALVVGGSSAYEIKGTVFIGEAEKVAPYRILLNGGEQVTYARADGAFVFRDITPGRYVIDIPAEDRLFSQYKVDIAEDGVVRAIEYQYPGAPKARAEYPLAVEPVAEFEYFEEREKFSILQLIMNPSFLTIIVPVGLLYLLPKLSEAMMDPEEFKKAQEEMGTQDPSALLQGMFGGGQQTADDSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVM3</accession>
    <name>A0A8K1CVM3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVM3"/>
    <dbReference type="OrthoDB" id="162834at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="212" mass="23388" checksum="AA353C3A8ADDA8DD" modified="2022-08-03" version="1">MDKLPEDEAVSYLPTSTEMAQAVKWVKKNPALAIGVVAMGITSLSVAKYLEEDEEQNQPDEESQEEPEDSADNPQPLPEPMEPVLTLKTYKGRGVRTQSDMTVLCEPCPKRCRIVVVPAAEEIRQHPHQASMTFYRARVRMTRAMTRAMARSGNKQTNAATIERMIQNSKNRFGGAIGAPLATALSTAIDTGLVFHSAEFLFFNDGEDDDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F999</accession>
    <name>A0A8K1F999_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Osmotin, thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW55005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F999"/>
    <dbReference type="OrthoDB" id="73819at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423397" description="Osmotin, thaumatin-like protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="28025" checksum="BCF5327F829E1946" modified="2022-08-03" version="1">MVKVTASLVALSALVLAAPASAVKINFLNKCSHEIDLQHAQGAVTWKSIAKIPTGGSHTHDTIGEAHAFRHGSSTQSTLAEFSVPNNWPWYDISIIPPMPGNCRGYEGCKAATKSVGFNVAMDIVPKSNANGANCRHLKCPKDDKNACADAYHFPDDTKTHDCPTGTDFDVIFCPNGAPPPAPKPAPAPAPAPAPKPAPAPAPAPKPAPAPAPAPAPAPAPKPAPAPAPAPAPAPGPGGFKYVGAPRPDSAALDVWCNQNCPSFCPGDMCGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FA89</accession>
    <name>A0A8K1FA89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0598 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FA89"/>
    <dbReference type="OrthoDB" id="10260024at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028108">
        <property type="entry name" value="DUF4505"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31449">
        <property type="entry name" value="UPF0598 PROTEIN C8ORF82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31449:SF3">
        <property type="entry name" value="UPF0598 PROTEIN C8ORF82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14956">
        <property type="entry name" value="DUF4505"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="25777" checksum="890CB3DCD068D798" modified="2022-08-03" version="1">MHRGLCTAADEDKYLELKQLKDIKSEEFYDEQGVHRRYFYYIDLQGRLFLENTRPKNIATSLKSAKFLRFFYSQLRPNRLKQPDAPRDEEINEIVPFLEYPYRSPCGKEMNFIKCADRPLVFEDLRRSDATDKWEFVFGGGELTMPFDPAALKISLTTGRLYHDVETKRFPRGDVESIGLVRSQLAVELGKTIHLLDDVEDDVIGEFEWQEQLYPIHSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAS8</accession>
    <name>A0A8K1FAS8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAS8"/>
    <dbReference type="OrthoDB" id="163711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="65320" checksum="38C96692D01120E0" modified="2022-08-03" version="1">MKQYTPEVVYHEPPHRQHHLYAEPAPRAVHGAPGDYQIGSNHHHTEFATLGSPSRQPTMYSEEDGGVIPSGRGYLTGEHDYNHEMYGSLRKGTVHRFFSREMIGFIAAVFSSAFSFQVLQGVTRPLMGTQLGLTKEQNVAVQRLVELPMTISFFIGLLSDSYPIKGLRRKGWMVIGLIINAVSVFAIAGVSAHFEAQKTKERSDLIVVVALLLIGIASIGCIITYVCIHTHVIELSQCEPLRRRGIFQADYFIFRRLISMTSSTFNYLTIGTGSTPNVSLSTTSMLLAVISIIPLPVLLKYWKEEHYSLPMAFRVRANIFWKIMQQKAVWRVLIFISFFGLFLAIKFNDSMTVIRNWAGGAANDDQLLTKSIQDLVMLLTILAWRMFFLNTPWRRFFAWAPVMMIFPQLLASMFVAFDFVRDRYLYRTLFSISYISDGITTLNLVVPLTEIIQEGSEGATVGLTLSLQRLISVFVSTNAQGLFRGANFYDVSAVKADGSGVRSDVFVSLVYNFIINAVAFFGLIFLPQQKLDAQQLRMYGGFTKAASTIIVVFSIALFVYSLVINVMTFVPSLSCHPLAGGSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCF8</accession>
    <name>A0A8K1FCF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Katanin p60 ATPase-containing subunit A1</fullName>
            <shortName evidence="7">Katanin p60 subunit A1</shortName>
            <ecNumber evidence="7">5.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">p60 katanin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">KATNA1</name>
        <name evidence="10" type="ORF">Poli38472_010666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCF8"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03023">
        <property type="entry name" value="Katanin_p60_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028596">
        <property type="entry name" value="KATNA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF19">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="294"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="302"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="552" mass="62115" checksum="56A3586808647081" modified="2022-08-03" version="1">MKHRLLRARELCLLGDYDVGVPEFRRVMQEIQRESAFASPQVRQFLQDLQEEYATLVQYEKTLHDLKAASERVQGQIKLQRRKVRASWDSSPSEPMDIDQRGSSRSRPNSLSPQFVKAQEKRLPPWAKTTAKQPDPPRNRPVTRSATARRVPVTSSQPRKSIRDRGKENNSKNVPARSSHPPMKSTAELALTRRLNRGSTGSGKRSSLDPPAKIPNSEENDTIAGKQKYSDIAKEAGWADQELIESIEREIVDQGERITFPDIAGLEHTKQLLQEAVMLPQIAPHLFKDGLLKHCSGILMFGPPGTGKTLLAKAVANECGLTFFNVSASTLSSKYRGDSEKLVRILFDMARYYSPSIIFMDEIDAIASARGAANEHEASRRVKTELLVQISGVPSGEAENAHVMLLAATNLPWELDEAMRRRLTKRVYIPLPGEEARRALFNINLKKVELAPDVDIEDLVANTDGYSGDDITNVCETAKRMPVKRLYTPDLLSQLSRRVMEQGADHSMRDLEQERLIVTKDDFTEALQNVSKSVGHDQLVRFQEWENEFGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCV5</accession>
    <name>A0A8K1FCV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cleft lip and palate associated transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCV5"/>
    <dbReference type="OrthoDB" id="378564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="68021" checksum="FB913C85B4EB0B14" modified="2022-08-03" version="1">MGAITKWINLTSISVVLFAIYFGFTVQQFYQIMYPTFINTEGPTLDPLWPESQALHAEFYLSPRAAWEVSDFNDPQVVVVGNFSELSYDWQDNERSAELEISRSALQAFAEASRPDEQPVVWRAIRSNNSVYLHVHVTHNRYDANPSATNYHRLATVHQSHPLIKFAPRPNAKNATYLLEPYFPHWYPPPPSHSEQYDEFDANHDFEKVDPTHKADVISFWKPHMAIRLVTDFKQYPYQEIPALVYHNLRYEQMKDKSYKYLPSMYLDDMGLTMEKLVPLNQTVRALPLKISYEPMSYARWQVLLTMEMAFKSQEAMGFANQDLDSMRSMLADTNPYLLAVTMTVSLLHILFDWLAFKNDISDWRQKTTEWQMVGVSLRSMVITLVSQVIICLYLMEEKATLLILAPSVLSLLLLVWKIFKVWRATRSAPTKTTTPTTSAVSTTQQADAMATNHLLFVLIPLVVGYASYSLIHKQHLSWYNWLLGSLTGAVYAFGFVLMTPQLVINYQLKSVAHLQWRYLIYRALNTFIDDLFAFIIHMPTMHRLSCFRDDIIFLIYVYQRWIYPVDTSRKFDDDDGSDAAHSHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDZ4</accession>
    <name>A0A8K1FDZ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDZ4"/>
    <dbReference type="OrthoDB" id="93514at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="33741" checksum="FBD08AD1478602B6" modified="2022-08-03" version="1">MHAEEKEDTRSPGPREKPKRKDANLTGYGTMIENPDVIRLCTELGMSRQDVWQLRKEFNDEDSDSTDTITLTSFFFLIQEQNRDLTKALLRLAVKEGDQPPTRRLTFDEYLRCVVTFSSFTEIQVFQFFFQVYADITQQRSGGTTVITVGEDELVQLSQDLQMLQFAFAGNIQVAQAHFAPPSASPIGTSMENWTFTDFESFARQHRVAFYPLIRVQHNVRRAGGFSDGYWAKRIKERQVLAHVLTYMKKNHGLLPKLPWRDRIWSAVMQNPTTVKRVHDRAKNFYMSSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE13</accession>
    <name>A0A8K1FE13_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003404</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a cytidine in 25S rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47780"/>
            <dbReference type="Rhea" id="RHEA-COMP:11911"/>
            <dbReference type="Rhea" id="RHEA-COMP:11912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE13"/>
    <dbReference type="OrthoDB" id="435282at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000164">
        <property type="entry name" value="Methyltransferase NSUN5, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049561">
        <property type="entry name" value="NSUN5_7_fdxn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048889">
        <property type="entry name" value="NSUN5_RCM1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21148">
        <property type="entry name" value="NSUN5_fdxn-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21153">
        <property type="entry name" value="NSUN5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="8">
        <location>
            <begin position="129"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="447"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="223"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="511" mass="57962" checksum="0F3027B3A5A14B44" modified="2022-08-03" version="1">MSELYKEAAELLQKLERRQGGLKSLAYAENVQHKRSSFALVCETLRYKPLLQELLTAVPQFKLQKKLKDTQRALLLVSLYDLLFGRQKIQGGGHLKKELVQHANAFKTALVRMKIKAKVSTNEALLPKENRRLELALPRYVRVNTLLITREETEAFIKEYSAKQDEHLRDLLVLPPGTELHEHELVKSGKLILQDKASCFSAFVLHGERSDKPGRAGDVIDACAAPGNKTSHAAMLIRQKPEIYEGCRVFAFDRSAKRLDLLKRRMKLAGADEVVEPCCQSFLDVKVDDPKYANVRSILLDPSCSGSGMTNRLDHLLDIASSQDQLDTAENEYEEDVASRLQSLADFQLEALLKAFSFPQVERVAYSTCSIFQKENEEVVVNALQSKQNRSAKRPFVLLKCLPTWHRRGMVIPGLNEEQAQSLVRADGHEDSTNGFFVAYFERTDRADGEEVADETEDAEEEAEEDDESTEAVGTKRKQLSDAQKEARKRRKKDKLKRKKEQQRQSTTSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE42</accession>
    <name>A0A8K1FE42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE42"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000848">
        <property type="entry name" value="GPCR_cAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00247">
        <property type="entry name" value="GPCRCAMP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="360" mass="41417" checksum="CB405AF52DCF65C3" modified="2022-08-03" version="1">MTMTMRALTATEEDANATLHVVEEVLLIVSSVVSFLGCAFIFMTWKSFSLPNYLSRRIVASMGLAGLITAFGFSLSIVVNGLGTQYLRHEALCYTQAFLLQYFYLASYLWTACFAFHLYQIIVVRNEYPERLLWTYRVIGWGLPGLPLLYLVLRQLTGHLGVGATDRRWCWISVHTHEEADAWQRSGAWQQLLLFYVPIGFVFVFNSVMYRIILKYLAMDPMSARLKRRVVLYLVIFFLCSIWGVINRLVQFGRADHQPNTFLTVMECICDPLQPLLNAVVYGTNRSMLDAYKERFFSSWFYTSLVSSDDEESGLDKSTSLLSHEDSTEDVNGDDSAFYYQDMLQRKLTYPSPEDEMNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFB3</accession>
    <name>A0A8K1FFB3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFB3"/>
    <dbReference type="OrthoDB" id="158114at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="794" mass="89643" checksum="36F3F05057DE25A2" modified="2022-08-03" version="1">MAQVLSPLPFASPASAMDRAARRRSSGDSWETSVSLASLTSLTSSSSGVPTSQDDSNTKKHSTKRSSRGPDLVIHVQGCAFGVSSYLLKRKCFVLYNHLRRLRVQSSSGSDLASDEIDALQMRGPAARGDPVFVLRQREQGRSTRNSLTPPRAITTTACPAAPPQQAPGDRKRSGRFKHVTCLNHKKKPEEASDTAKTVRTGTRIPSLSSTPPWIAFQRMQQQHTPPPRPEQAPTEIELEGADAEAVATLLEFLHSGKSTSLQESSAAQVVALCRWLCMENQLLYAAMVKLIDGLQSSEQWITLLLKCAKLQNAPNKRLLIDHLLVRFLQLSPEQAVAVVEAMPLQRLAVLKDPDLLARVMVCLFNHARHLEIWKRMVFVLELWMSTLGRRSLSHVVAVPLPPMPLPDFHDRFAEWHPVARLESLEVSGPHAYVSPTTLFTFGSYAFQVRLEREGTTLIQWRVMKAKMSVNQDNAKSEPPFTLRGRLTIRYRSGTYGALMEEDVPILYNHSPQQASSQWKVLLRAASKRARRIEESEEKTEEESSEEQPEQLPPPSTNDNNAEDEDEEEEEEEEEDAYARTYIKAIFPVRSKQLEPAATRSKAFDLMTARFSGQCFAWGHRICNLYHYLLLVTLFYQSPVGAPREIVQQSAVERMKKLPVETLLVVLESDRLRIPGGETTLVSTLTALCLNEEGYDNYSVEQIRALFRCVRWCFVDLEQIMQTLEQSRRELELYELIDDELDPAHLLTVPRRTPWGKDDDRRWSPYHAVTTQIEFEIEAGDRSLSPSKFPSFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG58</accession>
    <name>A0A8K1FG58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG58"/>
    <dbReference type="OrthoDB" id="73247at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="402"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="71205" checksum="01E9CEF19312A815" modified="2022-08-03" version="1">MSPAKKPTLPVSQAMLFASRFPDEDHAPQPLRRVQMAKLQQNTLPPPSPALSARDNAKPAQRRRQRIAHLADSRLWGFSVQFSPTEELRDDWQAAQETETKRQAQIASEEQARLAQEQQKQQFARDRERDYAVYLYFASRYGALDAVLYCCTPFPGRIYALQVEQAAKRLQHWLRERLLALRRYWIVMLARQVTQISFDNGLALVQRAVGNQKRAAIFLTRLKWRYAAMAFRSWYTVTQRQIEVRWRFRFAQEEELRVRFQRWRERIQAICEFKHQLKHVARRKQMVAAFVQWQEWQTRQEKLRLHLQKAWLKAQRDVWAVWKSYVVGRKRAKHSAQLIQRIWRGYHGRKRCKQYRDAGSCMVRVARGWRGRVAVRRFRDTMEIAQSLERIVDLLVWQEYCSAVHEARQQAVEEELERVQRQQAILLEAEREAEARVNAELAKVVRNDMHRQVQEKLQVIQQQVDPEQISERRASLRDLERKAKQLVLQGAVKTAREDALTAFYARDEGNRPVWVTSNCCVVCLASKTHEDGYRELLGRSQLCCSHLTSALTTNTIVDHLTIIYTAILSELHQNDQAFQTTLATRLIPIPRLWQRLERATIAMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGK8</accession>
    <name>A0A8K1FGK8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGK8"/>
    <dbReference type="OrthoDB" id="127101at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="51580" checksum="4011A2BA760E0BA3" modified="2022-08-03" version="1">MSAATREIESLGHAVWMPLTLLINFSLFQYLLTIYFRRRWELRVILLLMCAFIGFVTLIPFAHTNERLVSGLNEISETSCTLTFLIQIVILGRDVLQNARIRSLHYLTFIAELFCLFGLFVVIQNLVEINMQRLDPSPLDGIMEDGGLAFVFIVRFFFLTMIIGLRSWVIAQYYSGMAWEDAQAVWIRFTMILLSFDRLLSTSTGSARHAFALLCVVGFVTLIPFAYWDEEFVGDLNDVSESCCTLAFLAQIMIIGRDITRKVPIRSLLYLTVLAELLCLFGLFVVIKSIVEACAPRLDLSALEPLDNIMENSGLAVVFVCRFYLLAMIMGIRGVLRSKRLELLAYFLFVTHEYPWAIAENYTGVTWEDAQAVWMRSMMIWCIILTIRDKIKLNNSKVSQNTTSGPKEVSFHPTSIKSVGPKPMTVQSPSVKVINVGKLTVTRTPSAAKVTPKAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGM8</accession>
    <name>A0A8K1FGM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGM8"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40849">
        <property type="entry name" value="C2 CALCIUM-DEPENDENT MEMBRANE TARGETING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40849:SF2">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="61019" checksum="540A3920C1D06057" modified="2022-08-03" version="1">MSRLLWHTRLFYGVAAMSASVVVFSFLQEREEQEGREQEAAEMVVSSAHFFQAMESLQLTTQQKIEMRKFWRNLCNRKVQETRNEEEAASEASKTTEGDGETTLATAMAPSDPNLQLRVWEIQHFAREYKQVFPEIFPDEQVLAATRLAADAASQWNGIVQSTSSMIRSTGKRFHGLAMDTKDEMQGAMQRTVRKYLERALDVVADRLKHSLKDRHMPFYLQSNIDLAVDQFMPDVKVEIFRKTRDLFTQDSAAQPVPALTEIADGVRQLSIFGRLRGHILYHIFPHDKSIWMCFRDPWWIIYGCIGIFPVVGQLWWLFLFLIKDKTDEHQLCQFIVGFKAAQFVSLGLFSVAFGVSRYIKCIVSGALESCREYGPALQPWNASFFILQIALVWIAFFRLPYTVRPAEEKHPLLYRTSSMERREQRVFRDIFGNQLHLNRGGYLMKLCGYETVSFGIVVSLAAVILWFPFEPWQRKALFYWLRTAYGLFSLPFVIFKIPVLANVLMHTRRMGYNQYGDTVKIKKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGR9</accession>
    <name>A0A8K1FGR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGR9"/>
    <dbReference type="OrthoDB" id="165832at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="209" mass="22817" checksum="9149DBECDAF037EE" modified="2022-08-03" version="1">MDVPTWHPANEDASLTRQMLAKTNDTSSQRTEFKVMPGSTADLSSDAGRELLHELTNGGDGGSAAVEGRGFFDSSDRLYLQEQTRLEAERLSKQRADEEAELQRFRQNALKVQAQKAKMAVAEAIGAPMKETTTATASVVVIKAKKRTASSASTATQKKEKQQRKEEPKASTPSKMKSKDKSESKDEDKKPTPSLLMGYSSSSDDGEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI39</accession>
    <name>A0A8K1FI39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="8">HIU hydrolase</shortName>
            <shortName evidence="8">HIUHase</shortName>
            <ecNumber evidence="8">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI39"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="142" mass="15792" checksum="330ACE6439EF7D56" modified="2022-08-03" version="1">MAASASSRRLHALQSHLATSVVMSYKSPITSHVLDTSRGRPAANMRITLQALDASSGQWHQLNHGVTNEDGRVATPLVPEGMAFQPGTYQLVFDTKSYFEQIGVTEYFYPMATITFEIKQVDQHYHVPLLINPFGFSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIM9</accession>
    <name>A0A8K1FIM9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIM9"/>
    <dbReference type="OrthoDB" id="129052at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="133" mass="15127" checksum="E3687BA29B35770F" modified="2022-08-03" version="1">MKDRAVSLPQVDSTGDLRKPLASSGSSDSLNNEPKQASKDGLARRSQNRVTERKRTEQERRQEQEKRRLKKIEDDKLRKEHESQLKHRRRAEIYALNAILRQLQQEKLAKFIAQQQQSGGGDQNAGVAPSIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ81</accession>
    <name>A0A8K1FJ81_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ81"/>
    <dbReference type="OrthoDB" id="116571at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="244" mass="27019" checksum="F8C9722A82A70168" modified="2022-08-03" version="1">MTSMFRVLKGTKFLFEGRLVQKEEAPAQLRRLDVRADEMDLLAGVEITITKRLSLAEVDRMISCCRQHPPQCVITPKDPTNADQLAAFKDLALYLTQRGRAGVGTLSSGLLALVTPIADTYDYMRCLIVNATATVGDIGAELPRAITIQPLSEPQTAPKERKKQKTSHRRDEQPRAMTDNQAQERPDTADVSHVVQEEPSPQVRTDVCRLLKVLKVRSIDFVVGSDTPSSAARCISSFSSDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJY1</accession>
    <name>A0A8K1FJY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004305</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJY1"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="205"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="527"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="781"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="791"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="803" mass="90304" checksum="424DAFF24CE6F23C" modified="2022-08-03" version="1">MSDFSDDGVSEITAYAVVDGSSSAAKRAKKRKKRAQSGVSANGWQKVDLDDVHVQGFEDGCAYELEELTDYTIQKSETGAQILVIKGNKVEVDGFDEENAVNEQPVSDDQPKKKKKRSKKKKNAKAQEEADAEKKEEAEPVEEEEENVEMDEDEVEEAETAAPAAPVKPVNLPKWARFKLHPRLLQSLHECGFTAPTPIQEKTIYPALVDNRDIVGAAPTGSGKTLAFGLPILSQLLREKEQRGYVMNCKVLILTPTRELALQIQHHLEKMVPNREIGIVSLVGGMSMQKQMRVLSYSPEIVIGTPGRLWDLIDSNNEHLDDLNATLRFLVIDEADRMLQTGSYPEVEKIFDVLRKGKGKRATDELADLSEEEDESDEEDEGDDATTGEVKVTMLDDVLRMHQKQQEQQASEEGDEDDEEEATQVTPVRRTRQTFLFSATLTIPEGGRFQKGPKKHRHALTVLESVMKRVGLRGKPAVVDMSIDDASVGPQDSEAKRKRVQDNVALSLPAGLELCQHEVTEDSRDSYLYYFLTQYPGKTIVFLNAIHQVRKLANLLGLLRLPVFALHAEMQQRQRLKKLDGFRSNPNGILIATDVAARGLDIPSVDYVVHYHIARSTEVFLHRSGRTARANKEGLSISLVSPADSKYHAQICKMLQRPTGLSDFPFDHRFLPTIDERLRLAKGINDHENVTSKAKSEETWFSQMAKEADLDLDDNLLSEIQSKKDKGASRKGKNGESVESMRMELSRLLTEPLRPIGSVRKFRQLYQEIGSELTTDGEYRKRNASDDLVSKSKKSFKRFRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK54</accession>
    <name>A0A8K1FK54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008313</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK54"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421152" description="glucan endo-1,3-beta-D-glucosidase" evidence="14">
        <location>
            <begin position="21"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW65671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="304" mass="33696" checksum="45995787245E3C04" modified="2022-08-03" version="1">MKSLLLTIVAGVASICSVAAQGVCYDPDHVSPVTTDSINSDLATIRNQGFKAVRTYTVQHGNNNLGKLIVQNGLNASLTIPFDNANPSNSEVHIKAAIEAAHFTNGAARVTHIWVGNENLASVNEVPQPMFDFIGWVRSSVPAGVLVGTVQRSTEYLEPSRAGIYRWNDLIATSDVAGINIHPVFNPNTRADQAIGVVDSQWGRLYSEETRQRFPSLTWKLVITEVGWPTEGYWNGNSGSKEGAMQFMNDYKAWRAHHIDAQRSFYFQAFDLPSRSNDGPFEAYFGVMYADRSPKYNSYTYMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKB5</accession>
    <name>A0A8K1FKB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_005275</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKB5"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000007">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="16">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW62657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="527" mass="58771" checksum="999BA4082F6DE9F9" modified="2022-08-03" version="1">MEAAIVAKGDEIRALKEAKDPNNADKIKALVAELLGLKEQYKKETGTDYVAPAAKKSEKKAAPATEEGAEGKSKSQLKKEKKLAEAAAKKEAKKKEGGAAKPSQKPAKPSESAKPADGAAVPSDAELLLRQIDFNHKVASSGNSDNQVVTPWDVEAENGVDYDKLIVQFGCSKLDDALIARIEKLTGHRAHRYLRRGYFFSHRDLNLLLDAYERGEKFYLYTGRGPSSGSLHMGHLIPFTFTAWLQKVFDVPLVIQLTDDEKFLFKEQTLEESRKYMIENAKDIIACGFDVKKTFMFANTDYMGHFYPEVLKIQKCVTYNQARGIFGFTGSDNIGKAAFPAVQAVPSFPQAFPIPFGGRTDLRCLIPSAIDQDPYFRMTRDVAPRLGYFKPSLIQSKFFPALQGSSTKMSASKANTTIYISDSPEEISNKIKKYAFSGGGETKADHEKYGANLEVDIPYQYLSFMLEDDEELAHIGREYGSGRMMSGEVKQRLIDIMSEFAQDMQARRAAITEEQIAEFMRVRPLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKG0</accession>
    <name>A0A8K1FKG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKG0"/>
    <dbReference type="OrthoDB" id="160092at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="45390" checksum="F0B6277C27554F97" modified="2022-08-03" version="1">MSAALDWLLFENEPDAAFTSTESNGSAGGESPIKIEELLAEPTIELDEKERKRLRHREYVKKSYRKKISTIQTLRDQLDTLERDYHSMLGKRDNELALPAPTATNNSSPLMQKYFELTEIKNRLQRENEHLYAANAEFMKAEGRFQQLLDSDIQFPLSQPRFYISKLPPSDYAKIIADARDDVLKFAYAKDTLSTGYSVFGWTDKRKVTSEEIKFALVKDFPKISAYDLLMRCWGIFTIPERFSSIYNPGFITKFYPLQTIDDDTQLLFRTIQIDGMDFITKTVFLLARIKIDEGYLILFKSIDKDSVQFRESEINSIIEETRAIVTKKSTPKREMWVDKYIWIVIEDKGFEGCAFHFGGAATTNIWIKEVLFIALRWENLAVGPQFTLAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKI6</accession>
    <name>A0A8K1FKI6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">MoaB/Mog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_012271</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:31331"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKI6"/>
    <dbReference type="OrthoDB" id="4349954at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.190.11:FF:000001">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.340.10:FF:000004">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.980.10:FF:000001">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.980.10:FF:000002">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="entry name" value="MoeA, C-terminal, domain IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.10">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.190.11">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045515">
        <property type="entry name" value="Glp_gephyrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192:SF5">
        <property type="entry name" value="GEPHYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="MOLYBDOPTERIN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="MoeA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="MoeA N-terminal region -like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11 13" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="14">
        <location>
            <begin position="177"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="MoaB/Mog" evidence="14">
        <location>
            <begin position="443"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW67155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="611" mass="65163" checksum="62DBB4B1D9C644AA" modified="2022-08-03" version="1">MMRVDEAVGVVLSHSETLGVEEVNAGEALGRVLAERALSTEPLPPFRASMMDGYAVVAADGVGKYPVINRIAAGDAPTGAIRAGQVAYITTGSPVPDGADAVVKIEDTDGVYSHNSEVAVKILKAVKPGQSIRDIGSDITPGEVLIDAHEEVTSAEIGLLAMTGVTTVKTFRQPVVGVLSTGTELVAPFAPTPPGKIRDSNRPMLLSLLASWKVKTLDLGICGDQKDALENTLRQAFEKVDVLITSGGVSMGDHDLIKPLLEQIGTVHFGRLFMKPGKPTTFATVLVDGKKKLVFALPGNPVSSFTTCHLLVRPALKKMQGYPDSKCRHTQVYATLSHSVRLDPERPEFHRATVVWDAKTHKLVATSTGRQVSSRLLSCRHANVLLSLPTGTDIREGDAVPALLLDDTFEAVAHATSPAPAPRKEAPAASTQTPAVVKTFRAGILTISDRVSRGDATDLSGPAMADVLAHVKRVKIDVIRSAVVPDEVDAIQKVVTEWTDADHVDLILTSGGTGFSPRDVTPEAIKAILHKEIPGFVIAMLESSLKITTKAMLSRPVAGIRARTLIVTLPGKPKAVLENLSAIEDVLPHALHLVRDEPHEHHRASPQLLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKS3</accession>
    <name>A0A8K1FKS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thiamine phosphate synthase</fullName>
            <ecNumber evidence="2">2.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002063</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKS3"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="10">
        <location>
            <begin position="10"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="26390" checksum="3939B5EEEE10DAFA" modified="2022-08-03" version="1">MTSPAMQRGLYFITPSIGRRVRATEVVDIVKDAIVGGAQIVQWRQKPSKADFEALPELRREWDEQQASGFLLPIARQVREITKEHGVPLIINDSFELALELDADGVHVGQTDTNLRDIIAHLGTDKKDFIVGVTVRDGIQAQAACSHGATYLGVGPVFTSSTKPEANDGNTIGLQGLKECVAVASTFEVPVYAIGGLSLTERRIQRCIEEGGACGAAVIAAISDAQDRRLAAAEIRMEIDRALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL59</accession>
    <name>A0A8K1FL59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Origin recognition complex subunit 5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL59"/>
    <dbReference type="OrthoDB" id="365981at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="2">
        <location>
            <begin position="479"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="635" mass="71381" checksum="68B28ACAEAFBF1CB" modified="2022-08-03" version="1">MAKMLHVPSVVGRHAQLEELATVAGLHAHANEDGGRIYEPAPPLVVVYGGVSTGKTVCVAHALRRHASTFAMLDCTGVLSTRVFCRDILGQLQANHRARQREKNLGFHDGKPMQEIELAEDDGITITDAPKPVVRVKPKRSVRNRKKPQKKKKTQQTRGRRRVEDSEDGDEESEYEDEEDDEEEEEDEELSDGLDEDDELDGVAPMMTDKPVGLESQKYTSLNFLAFVKALRLFMNSVIKDDADTTSSRHRRTMYIALDNVEKLMDRNLSRLLTCLLAVNDQLDYMHILDPDGAPWSLSVLLIARAVSLRFELFLETSHPSFIHFPPYKKEEVAEIVAFQIERASTGESIDPNNATLLRKWLVYMYDLLPHAHNDWLEFRHLVVQMLPSFHDFFDIVSANDAELPQLVRAKSPANSSTTKSMSWKQLQNMSRESVSVLEKSRRRHLFGYDMVGSVDGDPTITSGDPMAFITFSKLNRSCLLLIIASYLSSFTPHEADSKFLSSSSGVKRKKRVMKAASGPAKTTGKKARSDIPQQMIGPKMFTLTRMLAIYSTLQVENDAANGLTAADTPVLSRSRADIFKHLAILIRLRLLQRMSPPNALDQLQFRCVADIRLVEEVARHIGFPLDAYLNTHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL93</accession>
    <name>A0A8K1FL93_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP97 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL93"/>
    <dbReference type="OrthoDB" id="2163395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038792">
        <property type="entry name" value="CFAP97D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029488">
        <property type="entry name" value="Hmw/CFAP97"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33768">
        <property type="entry name" value="MIP11318P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33768:SF3">
        <property type="entry name" value="MIP11318P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13879">
        <property type="entry name" value="Hmw_CFAP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="587" mass="66592" checksum="46BA6E9DAD2DC59B" modified="2022-08-03" version="1">MNKKIAFDNRLCYERDVIRQHDIHHHKLQTMLPTCQSPSRVYLDSNEPTRRAHLLLNRKRQQLEKEKQMDIYTQNQRLATKMEHILNRQENVILAAGTPQTPSLTSPRGGTKASTTVSPRKPVHSPAYVHMPGIRLNANQTPMVDCYLSQEFAMGRGNACKKDTLVNRGVQKQKQRRIAEENRRLKQRLKTQKPYYNTKKWDTQWQESSHKFQHLHQNTTVGHLLPKTSPVNKQHGGIARTSRSPLVGRRMKARHDLPTITTTPPMSTTGGTHSNASEQSVLSSGRSKSEEDDGPDVTEYPPFVLLEATTRKGVELTVEELQIEMCDPSSGIVQAGDRGLVVRGQWRDNVQGECYVGKDTLEKIAQEIDDLEMMIKLETISSLAGIGNFPRLSALLTEDELQQLLLKLVQVMNIQVIEESNELVITSRFIRSPKAVADRGESKSPYRAIRPRTCPSTIPSDVAPVPPDEYCSRQYDGNIEDIERNDQEIARFQAVLAKQLALVLNQERTRAGIRISGLYYTARYWFDPSASTLKATVTPTDPSKPLYTTKIPFSIKDVTTSLECINSEAQHPSIVAWERIFEWLEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLB7</accession>
    <name>A0A8K1FLB7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLB7"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="570" mass="64524" checksum="609E9CEF6323FEEB" modified="2022-08-03" version="1">MVTHQAYWAGAAHHIQIQTSDCLAKPLIRNPDWQWSLLEVQSKDQVSDIVLALPDPGWFARVISYLYGIVTLVMIARGLIAFLLQNRVAWYIPDKIRYSKDHRLFRYILPFMPFAMLLGDEDRAIIPFKGSLLIASDVWMNHWLYITLSILDSVANIRMAYCAIHLGTSYVMLRITLTNFLFVCQALTRMTWITCMIHTILRLVFKITVHSLRSMQLIRSVTRDKLIRLIDGIAMFLSFKILMLFVVQPRRVGLRNKGQSTDPILCLCLLSGVKQNNILLCVILYTMMKITNKTTFMTRQTPYKAGNYGGIPKIGNFWRSELMCDFVTILLMLTACGHVLGLHLMLTPFRKVADNGVMKQLQKRYFWVGWDRLMVAKMLGRDPTKPGVIVDGVARTQCPLGTLIQLMFQSGPSAFVHLAGDYIFTGSGFSNEPRTFKFPVKHATAIGLCHGRKSSVYRKVIATHATEGESTTTIRRRSVPLITPIDSSITGSRTGSIIQREKASICDRELKLVADGYLGKMLLIDKAKPDVMTTNKDTGLREFIVSDALTSISILDIKHLLGNEKTLRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH6</accession>
    <name>A0A8K1FLH6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH6"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01167">
        <property type="entry name" value="LPXTG_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431284" evidence="3">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="35767" checksum="0CB2E1A9C0F19EB4" modified="2022-08-03" version="1">MWRSVKLGAIAALAAAHADATKVQVTNMCSAEFDLSHLGQGSIISVEKLAAGASVTKELFDPAVSQLFKAGVGAQATLAEVTVKNKQVWYDISIIPTGNGVGPEWCSTFQECKLSTRGTGFNLPMQIIPSGGANPECTPLSCMEDGCPDAYLFPKDDKKMRDCPMSTNLQIIFCPGGPGGKTPPPSPTPTPTPSPTPTPSPTPSPSANNSSSTVASLEEGVILASSSAGSSARASKETRSMDVSDEEPSAGETPAPTPSTTAAPVQAPDQKVKEVNTQSSGETSTGAEVYVLAIMGAVGVMAGAVIFVVRKKKQELEALDVKSPLPTGTRDGSLMMVTPGEAKVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM9</accession>
    <name>A0A8K1FLM9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM9"/>
    <dbReference type="OrthoDB" id="118048at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="21347" checksum="AE81B478FE52D625" modified="2022-08-03" version="1">MKSTPSRALVSADSFDERLRNVFSLHAATPVLNEYLSSIQIDDDDPGFVLSWDFDNLNAFVVAANAQNPARAPGWLQTRPPQMTVDSFTDDLVHELHQVAGGRCGRVLLAPKRPDQFLAIGGGGGGGGTLIALQDDDFMQDAAQVALPVLNNVERYIATTYYLTDTKAQRSVENNLPPTRRNGQPLRRICRIVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMD9</accession>
    <name>A0A8K1FMD9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMD9"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="76"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="235" mass="26834" checksum="37FADFE32ACC64C9" modified="2022-08-03" version="1">MSKKIAAQLEKLRGEEWDSDSEHEQDATFENGGDFVDFEAKDDVEMESEEPKKKKATPARKAAAPAGGKTKLKESNVIYLGRIPHGFYEAQMRGFFEQFGTVSRLRLSRNKRSGKSKHYAFVQFEEPEVAQVVASTMNGYRLFDHVMTCHIIPVSAIHERMFVGANKTFKPLPWRAIARNQHNAERSYEQTVARNKRLVKKDNQKRKILQALGIKYDFPGYAAKAAPKQKHVVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMN2</accession>
    <name>A0A8K1FMN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">folate gamma-glutamyl hydrolase</fullName>
            <ecNumber evidence="3 8">3.4.19.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:56784"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="EC" id="3.4.19.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.9" evidence="3 8"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMN2"/>
    <dbReference type="OrthoDB" id="64220at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034722">
        <property type="term" value="F:gamma-glutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046900">
        <property type="term" value="P:tetrahydrofolylpolyglutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000054">
        <property type="entry name" value="Folate gamma-glutamyl hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015527">
        <property type="entry name" value="Pept_C26_g-glut_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315:SF0">
        <property type="entry name" value="FOLATE GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315">
        <property type="entry name" value="PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51275">
        <property type="entry name" value="PEPTIDASE_C26_GGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035459346" description="folate gamma-glutamyl hydrolase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7 8">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615527-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="36323" checksum="A4D04DB757DE0034" modified="2022-08-03" version="1">MSRLLLSFLAVLGVALHAQCTVAASPRGPIIGVFTHPIAKHGEYLAASYVKWVEMGGGRVVPIPYHAPKEYLKELVPQLNGLLFPGGAADVNEAAKTMYDIAIELNDKGVYFPVWGTCLGFEWLVQLTADDLKALESGFDSENITLPLNFTDLAPSSRMFSKAGDDIYSWLANKPITMNNHGQGITPEQFAKFSKLNEFYNVLALNVDRKDRTFISAFEAKKYPIYAVQFHPEKNSFEYGEYENGMPYEVIDHSYEAVLMGQYFANFFINEARKNDLKFADPKIERKALIYNYQMSTITDPGFVESYIFKHDQETNFWRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNG4</accession>
    <name>A0A8K1FNG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNG4"/>
    <dbReference type="OrthoDB" id="168113at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="754" mass="82794" checksum="CB2F982420C6A29E" modified="2022-08-03" version="1">MSKAPKQRKAQLHYQPYQASSASSNGDGSGLDFHGADLPMMDPVLAGFSSNLSRNLWDDWNESDPNLVKFDMFTDDGSSMTATNTRVTQTMTQGNVSMHQEPMHPMAASQQAHGETSHHVDHHSVSMSAGSGSFEPMELDSARHASGGFSAQMQGLPRMHVKRSLSEDIVSMLDDETQDPFGHHARAQTKAMQQQQQHRQHYTPTSSAQNKTSEPMNTQESLMVQNSTAWMSGFAQEVPVQGPPSPRTQARIDAHNSRPEPTPLERAAAAIATTMVAVPNPCKEKEAPPAPEPSASSTATSNVMTPSPFNAFSFMSAAIEGKADGSDGKNGDKNVNMFGNQGMMMPGFMMYSMPMMGNYQAAAAAMGMMPMGMPMGAMQMSMGMPMNPMGMAMGPMGAMQMPMGMPMMPMNPMGMQMNPMGMAMTPNGNATADGNAGTLSANSATAPGATTPANGTTPDGLALLKGKPLIASKDPRGPGFVSIARKPEEPEVSTILKSLMEEEAKKKEKKLERNRDSARESRKKQQTYVETLETGIKRLQINRDLVHSYRWGVTGPSSLTLASLSSTSPGNDTHNRNRELVEWKTRVNVVTGASESFSNLQNPAGFQSLMRVNRQRRALGFSRDEKERAIWKCFVCVGKQLAALRQRILELQVFRTLETNPLTADLRDQLQLTEQQRLALQCHSNRIFAQEVEALVKLFKVFFALRDQALRFNLLSPSLEQYFRETCAMDQLQRLLQWTETYRSTIQDTLSLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPR4</accession>
    <name>A0A8K1FPR4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPR4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="24882" checksum="116CF235F9ED6348" modified="2022-08-03" version="1">MASAQQRALFDAAVVGDLEGVKHFFSDPSVASNITQTNTRHREIRERELEGNRSPFRFFPEPGAWYRYVPGEDESPPFRYCLFHTILRHNHLDVLQWFVSATGCESIADTMRGLVDRVANAIVRHCRDAAPLEILLGSYLFTELLTPLERKFALEELEETIDRHGKDDLLRVVVAHGVEIDEFSEKEKEPEPTFNDSPMVFPPLFIEFCERWACEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPT3</accession>
    <name>A0A8K1FPT3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPT3"/>
    <dbReference type="OrthoDB" id="166605at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41629" checksum="B65620D3A55F8DF7" modified="2022-08-03" version="1">MDSLEDRMTLEAVDFFLDNVTSSDSHGAASDSSPQSVAPARPVARKKRKPTYYVRKEQASELQDEVQTLRERLAELEAKHGGGDAKLSSTVTQNLRMRHHVLQHANQMAGLQSMLSSYHASGAYCPLESFIHLPLDVDSRRRTLLALKAQKVREAYAYITERIRHMDVSRSHFAVERFETPEGHFGFAHFDVTPFEGQTLRGVYDALRFFFDHQEMSVSENLGLITIRETEDEDDEPVLQCRLVTTLPSGGELEINSAMFLDFCEHKNSNGGPHGIITLDFVNHDDMYPYQPDLRSRLDLNNVILVVPVEPSDPNSPSKPKIALVRACFGRMHRAANGISKSMENVAQDFFIRFGQVMLQVVQDHLGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPU2</accession>
    <name>A0A8K1FPU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPU2"/>
    <dbReference type="OrthoDB" id="166620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="429"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="544"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="630"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="562"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="651"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="745" mass="83528" checksum="2D371D237225A5EC" modified="2022-08-03" version="1">MLIADAVFQKDSSQSDVFHSVEDCIDGLLAGYDCSVFAYGQTGTGKTYTMSGLPPNKEMSVESDEDFIELIQRQSFGIVPRCIQKLFDQIDKARTEEGSGVTFTVYCSFVEIYNEKIYDILSANLVALSPSSKRQRDVRNLDHRAGWNRPQPTKETPSLPIRQKLDGSVFIDGLTSRKISTRAEMLQAFCEGSMNREVRDNLYNQHSSRGHSIFQITLRKNIESEHGTKSSPRRERNEASNAGAAPKSRLSRLFFVDLAGSEKWHVNGSELSDKYASELASINKSLSALTNCVLALTQKERAHVPFRDSVLTRLLQSCLQGVGRTAFIVTVSPAKDSLEESFATLRFAERLKTLRCRPIRKKVFSNELMGEQRMYYERQIQNMRLEVARLRELLKKAQRRNQEITENTATVANLALTEENRRLKELLMHSERNRLSKRDEERVGRSSLHAATVSPQQMTGKQIVSPRPFSEDESSKSASLDDSSDGIGGSSTPQPRTSRRADVVDVESGKAATGGDQQQYSTLVNQLQDQEARLNWMLEAEMEAQNTRTRSQTVIEGEEAKQTSVTSPTRKPTITRSWAVERALQRNLPTIPQPVRNPHGDGKDKTPVPSESNAALIRQRYMINEEAAELRRRKEDVVRDPARTTDKSRISSHASSDLAAASVSQSQTKHTPPTRPIAPSRPARGIEGHTNSPKTTDQAKSSSILKLFGTGTPDQLGKSKDELVDQYKRARRAELEAMLRTMVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR62</accession>
    <name>A0A8K1FR62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR62"/>
    <dbReference type="OrthoDB" id="151325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="46"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="27409" checksum="CA851B1BE84C2265" modified="2022-08-03" version="1">MTLLEVIVPQLLTHAPTTLTDRNRDFNVNLCNFYGCYSRKKSWARCMLLNVAFPKSLVIASHLFRRSNEYLSLVVMQISNIDDERNGLLLLKPLKYAFDHFQISFIRDDTDAFRLKLFDPSIRSTPLIDPADRNGNKVFSTEQTRVLLSNVALSKKRCRFDVRTTFGDVDGSALTFAGLERPFCRCLNLQARLARMVALKKIWIDATYDFQDFWSEVSLDDKMEMFHRSILKSDAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2J2</accession>
    <name>A0A8K1C2J2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2J2"/>
    <dbReference type="OrthoDB" id="162906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="124" mass="13137" checksum="FF546269E2DF921E" modified="2022-08-03" version="1">MDPQKPPKEAPYDGNMGVPVAAPAPGYPPHAPQHPYYPPGAPAYGQPAPVDAYGRPIVNAVPLQTQTTVVANNANIRRDAAGNALCNKCSTPYPLPAGATSWRCRNCHELNNASIYGDECCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3A9</accession>
    <name>A0A8K1C3A9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013253</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3A9"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462722" description="Endothelin-converting enzyme 1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="37"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="472"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="75511" checksum="EA0E4B5384E1ACA1" modified="2022-08-03" version="1">MTIFVSSTLAIAALAAKHVNAEFPPEVIEKLDTSVKPCDDFYQYTCGGWMKNYTLPDDRQFYAYSFTGVEERNEPVIEEILKEDWPLIGELWDSCTNVDAITAKGTEHLQKDLSRIAAVSNKKDLFVLGGDLSSIGPKFFSGASVTADAKNVSTNALYTGVGSLVLPDKSIYLDKATFTSVEPFYRKYISTVLTLAGVNPSGNQQQQNSTGSTTDAEDAIINIEKKLAAILPTDEELSVENSYNAIKYSDAAKKWPLTFGALADGLRLTEQSSLTDNSNVIFTTPAYFDRAERLVDTVDVKDLKVYLSFLYVNNYITYLGQPFLDAQFELFGTVLSGSTAMPPRERTCTVAQIAFFPDLIGKYYFLKMFDVDREENVNSMVKSLESAMADHIAKLDWLDDQTRAKAEEKLKMITNLVGHSAQKKNYPFTLKRDDYLSNVLTIKSSNWAESLKKVGQEVDRSEWSLSGATVDAFYTPALNQIIFPAAILQPPFYSGGSHPVQNFGAIGAVIGHEITHGFDTSGRWYDGQGNQVNWWTEATAKEFESRAQCMKEQYSSFTAYGNSGKPVGTVNGNLTIGENIADNGGVSLAFDAYHTWAKSNVTFDSNGVKDDEVDKLFFVSLGQMWCASIRDDYAKQILSVDVHSPPHWRVNGAAMNNDDFAKTFNCPVGSKMNPEKKCKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3B1</accession>
    <name>A0A8K1C3B1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.160</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:23324"/>
            <dbReference type="Rhea" id="RHEA-COMP:11106"/>
            <dbReference type="Rhea" id="RHEA-COMP:11107"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:76596"/>
            <dbReference type="ChEBI" id="CHEBI:82883"/>
            <dbReference type="ChEBI" id="CHEBI:85027"/>
            <dbReference type="EC" id="2.7.1.160"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KptA/TPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.160" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3B1"/>
    <dbReference type="OrthoDB" id="419694at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000215">
        <property type="term" value="F:tRNA 2'-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="entry name" value="RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042081">
        <property type="entry name" value="RNA_2'-PTrans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684">
        <property type="entry name" value="PUTATIVE PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684:SF2">
        <property type="entry name" value="TRNA 2'-PHOSPHOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="25976" checksum="6C990A392D7D6D5B" modified="2022-08-03" version="1">MATAALKQAAKKPRRRLGGRKDEPMEVRISKTLAYALRHGAEDLGLNMRASGYVELQELLSKPLCKEITEEQVEEIVRTNTKKRFTITTDESGAVKYIRANQGHTLQLVSDDALLTPLEDPSELPYCIHGTYTKFWESILDNGLSRMTRNHIHMTPTEVTGGDVVSGFRTNCDLLLYIDVPLALTDGIRFYRSSNNVILSPGVGESGVLERKYFIKAVKRDGTVVFTREATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3D3</accession>
    <name>A0A8K1C3D3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4954 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3D3"/>
    <dbReference type="OrthoDB" id="118763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032533">
        <property type="entry name" value="DUF4954"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16314">
        <property type="entry name" value="DUF4954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4954" evidence="1">
        <location>
            <begin position="40"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="641" mass="70267" checksum="B52017F5242AC757" modified="2022-08-03" version="1">MSRSVTSNTSIAALADAMTRSELLTYVQQSQALFDLPFYPLSTQEIEKLKRHGNTAEQWENVRKTRMDAHIAASRIRDCHFQGKVVLGLFDRDHEVDGVTFPSGCYRSTLKNVLVLDNALVKDTTAISNAIVDAHASVIACGSITCAKKTAFGNGVTLSVGVEIGGRDLRVFAELPFDVAREIAGNRADTNLLEEYNEFVQQYTSKVTSRFTLVSRHARLLRCPRVDASFIGSFAVVEDSDVHGSSILSTQSEPSRVRCKSIVRDSIVQWNSVVEDLSFVERGFLCDASHVGRHGIVMSSLLGPNTSIAEGEVTSCFVGPFVGFHHQALLIASYWPEGKGNVGYGANVGSNHTLKAPDQELFPGEGVFFGLGCCVKFPSNFTKAPYSVIATGVATLPQSVEMPFALINTAGHNIPALSPAINEISPGWVLAQSVFTVLRNESKFATRNKSKRTSVSAAIFRPEIVQYMTEARKRLGDAAGKAKIALLSGEAIYTDRQVAGLGKNYMREASRVEAISAYTFFIHMFALDGLLQWLESQRQSNQPIPTRLQELPSASYELETLKAEFPPETLITDALKDLVQKRRAIVKNAISGKSRDDARGKRIIPDYALVHSRVEDEAAVRYAQGVTDNTEKRVSTFISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E8</accession>
    <name>A0A8K1C3E8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3E8"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429567" description="Ketoreductase domain-containing protein" evidence="4">
        <location>
            <begin position="17"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="35299" checksum="D1267CE8904B4128" modified="2022-08-03" version="1">MLLLWVVALWAALTWALRSWMYRPFSLDDKVVVITGAGMGIGRRLAEKIYLTASNVTLVLLDINQDALEKTQRHLQELGKKSSTVRIYQCDVSDESAVERCIQQVIADVAPHPIAVLVNNAGIVSGKSIMELTPSQVRRTFGVNLFAHFWLVKSVLPSMKQSDDAMIVSIASVLGFTGGARLSDYVASKSAVIGFHDCLRLELLHDQLRHIRTLLVCPLGIRTGMFDGLFDSDHGLFNLQRIFAPMLTENEVVESIHGAMLRGEHQVVSCHPGWLGTFLAILAPITRVIPPVIRDQLSLAVGAVHGMDTFVGHGSKKKATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C423</accession>
    <name>A0A8K1C423_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008707</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C423"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF547">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="72"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47713" checksum="E7CFD1C833683CC0" modified="2022-08-03" version="1">MEALHQVEFAYNRKLGRPTYAEVMHRGQPPRYPPFAVQVPVMFLPWDEDRGGVMCFIHPGHQRVLETPQETQDDASNIGICRCGVVKYGKYFQRNRLAEFGAYDVAVKIMNKGQLLLQRDDVLNEVRVMAQLQPPGFSGIYSSPHFSQWECCTDAYNEYIATDLAANGSLVQYVKRRLTDYKRFAVQKLVQTMSSLGNIEAVVNAFVAEAWMAEALYIFSGVMKGLAYMHAQSVCHLDLDPCNIVIDKNFVPRLIDFGSSEIMDNNGFAGQDDRLVKFKPLYVAQEVRDHNHHEPPRPGFLGGAADMWSSGVLLYQLLCFGYPKGHLALICDQNWRHNLMCHAQEGYGACLGEQGCLICFRNIQFPPLVYDVFLDLLVPDHPAARISAAEVVLKLQPLVEGYEPDFMMRADATLELVLQHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4T6</accession>
    <name>A0A8K1C4T6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4T6"/>
    <dbReference type="OrthoDB" id="10264920at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027012">
        <property type="entry name" value="Enkurin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052102">
        <property type="entry name" value="Enkurin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490:SF2">
        <property type="entry name" value="ENKURIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490">
        <property type="entry name" value="ENKURIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13864">
        <property type="entry name" value="Enkurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51665">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enkurin" evidence="7">
        <location>
            <begin position="237"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="41218" checksum="F1D9395B37D95CFF" modified="2022-08-03" version="1">MSAATGFRLRDANASDAVAALLHPNMGYRYVGYAYVEFGAVELSERLYREQLRRRGIEPKDFEKANRLQVKRLQAEKREQRRREEAAKREQFKLTRFKSVQPRVYEEKKPAEVDQPPKRHEFLRRGGSAAALLKNKRLDQPASTLDSARTTAGGSQSLRCPSPARPNRHVKPPVPTRKELEELNEKLAKLRHKESVDYVNSNAWEVIKKSPPKPIQDDNGQNQVHSSFGRIPEYLLQRKEQWAFEEEERRRNAPDPDCPPGMVRLDEDERVKTLGILHQSYEAARRQMSALPLRIETFSQIRRKNELEARLQEIEDAIKVFSKTKVYVAKPIEDEAPPVSSPSPVRSNRRRPSNAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y8</accession>
    <name>A0A8K1C4Y8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y8"/>
    <dbReference type="OrthoDB" id="20035at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="279"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="607" mass="68523" checksum="A27B9BD3EB89D45D" modified="2022-08-03" version="1">MGSAGKFPLPVDFFPEIVCTDEQIQSLQYEADKQLRDVMKAVKWEMHYEDGTQGWKLSSSKKHFRENGVRTYSRKPDSLTERKSRRLDFKCMGKVAMPLNQTMEAMYSDNTMDYRRHLALMLDGCLDAAVLHMIKGQTDKNPHQYLGINWLALRNPGFLGKKRDICFLRSTGITFDAKKNKLGYLVIRSIDVPECHSLEHSHGLHRTKMSAVMLLKEAPDQRSTSIIIQGTLPMSGFSSSKLVDFVHSAFMSAISNFNVFFVTKFISHEGDLNRIGNGSRDSKNCYLCTKRFSLLRPRHNCIACGESMCRDCEVSRRTSNLERNTIDIRKTMIMEKDGVQRFCRKCVVSARQRMNDRSYSPKAGVEFPQTDSSNITSGVSSVASSPRGYDIGERISTISSNSSQCSIQLTWPDLKQPKKSRQSFSAYGSSVSAVPAGRRPTSLSTSQIPESPLTIRTKNYDFGRDRLETDPWEDYDNFEHPDQSFGADSESGQAYASRNSAFSDKDMDLATRLREMSIRAQETLDATKRNSLMMSDTNSIPRTSEHRPFQDLDKSIAEQADLLNVIGFVSTGRVYMEGSESGGVRMSESSMASIDESERFEVLDEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C606</accession>
    <name>A0A8K1C606_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C606"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="6">
        <location>
            <begin position="77"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18285" checksum="83CA93E7FC91BC21" modified="2022-08-03" version="1">MLGALSRRGARLVARSSLRAASAHAVRRPVAVQAVRGFATSDDGSHSDFQPKFHAAVSTEKDEILKMIESHVKTYPIMLYMKGTPSAPQCGFSMQVVRILHAQGVSFDSVNVLDHPEIREGVKDYSQWPTIPQLYVKGEFVGGCDIVSDMHKSGELNDLLAEFKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C670</accession>
    <name>A0A8K1C670_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C670"/>
    <dbReference type="OrthoDB" id="166340at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899">
        <property type="entry name" value="PAPAIN FAMILY CYSTEINE PROTEASE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899:SF1">
        <property type="entry name" value="PEPTIDASE C1A PAPAIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10850" checksum="F0E1A45BC888F663" modified="2022-08-03" version="1">MQQQLDATDTTMQAKDVADAVVSNSAMSHCGQLPHKFAVEQVTPLKTQDNRGTCWDFAAVGVLENSYRAQGVHHGWLKENEYIPISEQAYGAEVLRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C692</accession>
    <name>A0A8K1C692_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CFA20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C692"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="2">
        <location>
            <begin position="6"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="32267" checksum="DCA92E3F8842DFC8" modified="2022-08-03" version="1">MTSPRPVWQEPYVEVLRHGLAHRSVGWQQQGDVEQVSDALIHKNVFKIRGTIAATNYMRIPRDVVQGTYGLGLTGRYVYIQLRRVRDLPLLLHMDLVTSKKTTLRFSLSSMYTALRSTGTVLRVPLQLNKSWTTVVIDMVELLACHTFNDYCRENYRCLKAVTCCAAMNLRNVFISSTLYTTETLPVALALPVAYAAQGGPYVWLSLPADEMKNHAASHRKTPTKARQRNESDFEEVEDTTSETEFFVMLDSQSDHKNTPLSQVLITSPLQENQNLRLPLPPGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6J8</accession>
    <name>A0A8K1C6J8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6J8"/>
    <dbReference type="OrthoDB" id="73161at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="108" mass="12297" checksum="FEAAEEADD0C34FEC" modified="2022-08-03" version="1">MIMEPATHVQYVAGLAEHWQRMGQRDYLTKTLYERARGSVVAVSFVTPPKALVGLVCRNFYTASLRLVQYNVDGSVSVLLDNHSLMQYANCEDDAQKWHVIHLDKVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6U6</accession>
    <name>A0A8K1C6U6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6U6"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="61"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="36485" checksum="6FE39531D301596F" modified="2022-08-03" version="1">MQQTANTSARGFRLQRHVDSLLTEPKHFAPEHKRMAKISTGVNVEYVLHEQQQPGATKEERVVLIRGFQEVKEVWTPTVDQLLRQWPADSNLKILTFDNRGAGRSDATWGRYTTSQLAADALALMDHLEWQDAHIVGYSMGGMISLELASAAPERVKSLSLLATTRGKYTSDKDDGTALRMLFTRDPAALAEFMVGILYPETFKSRKMDDSDEIVHHQLIAFHRHRFENAAPSRFIGWIGQLLALVTHYVSHERLATIAQAGFPVLIIGCGDDDLIPGRESATLATHIKGTHVKYISYDDAGHGVTVQYMDEVTEELLATFRRAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C734</accession>
    <name>A0A8K1C734_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C734"/>
    <dbReference type="OrthoDB" id="1703270at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="205" mass="23425" checksum="C7EEC055733016E8" modified="2022-08-03" version="1">MGISRDSRHKRRETGGKRKQYRKKRKFESGRQPANTKLGHKRVHTVRVRGGHTKFRALRLDTGNFSWGTEVTARKTRILDVVYNASNNELVRTKTLVKGAIVLVDATPFRQWYEAHYGTKIGQKKNAAAETADETKKSDHVVRKIAARQRTRVLDQKLDEQFASGRLFAAISSRPGQSGRADGYILEGKELEFYQRKLATKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7E9</accession>
    <name>A0A8K1C7E9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 19 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7E9"/>
    <dbReference type="OrthoDB" id="160168at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00325">
        <property type="entry name" value="chitinase_GH19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.20.10:FF:000001">
        <property type="entry name" value="Endochitinase (Chitinase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.20.10">
        <property type="entry name" value="Endochitinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016283">
        <property type="entry name" value="Glyco_hydro_19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595:SF79">
        <property type="entry name" value="CHITINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595">
        <property type="entry name" value="CHITINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001060">
        <property type="entry name" value="Endochitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0611">Plant defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035465296" description="Glycoside hydrolase family 19 catalytic domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 19 catalytic" evidence="6">
        <location>
            <begin position="65"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="128"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="256" mass="28029" checksum="20F335E4375BAA7D" modified="2022-08-03" version="1">MKLSVVFTALCALAYGHELVSANNSTETVDTVDVPVEYETAAAAAATGISRYMTEAQFKSVFPNAIALYTFKGLVNATKKYPAFANSNDATKNKRELAAFLAQTAHESDNFKAAEEYNHASYPVSQYCNPSQVKCASGKRYHGRGPIQLSWNYNYKAAGNALGVDLFNKPELVAKDKTITWQTALWYWMTPQKAGRIIHNVVTKDDGFAQSTDIINGGLECGPSAPNKGNEQQRIKYYKALCSKLGVTPVKKVSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C803</accession>
    <name>A0A8K1C803_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C803"/>
    <dbReference type="OrthoDB" id="123702at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="32911" checksum="AE3746460146FF69" modified="2022-08-03" version="1">MGGHGRALELLQDVLHRHRDQKTDAKALVEAVDNALQPLLADLFASRFFLDVDACQGVLIDILSCRGFYIADTYHFEDLRRLGFFRLDGNNAKKRLGCAFLVFSKLLGQLARLLGDDGEFEESLARIERASYDFDELMVFHLQLKTLVYRNKRVLLSIFHAGTGMERIDSVSVYDAKMRKVVAMNKSNSGGGTLDAIVVDSSSKELVVGYHNNGEPSKDVIRWHVGPPDEILDEALYTAELKKANVVVDSDVFVLVTTARVSEEFDLPPCCGLVTGDMFGDYFGPLASLVELSLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C811</accession>
    <name>A0A8K1C811_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C811"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482138" evidence="2">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="16215" checksum="4E65F7BABE316E1B" modified="2022-08-03" version="1">MRCAKLTALALGGLCALWASNASAAETFEFHDGDGNVVDNVSLENILSILGYEVDEASGEVTARITKPPVVKDGSSDDDVLPGVVVAPSTKPEATAAASTTEGSGSGSRGANHESITVGSPEGTSPAPEPTPAPTLISPQEQCTAEELAEVEAFRKANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8D4</accession>
    <name>A0A8K1C8D4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Anamorsin homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Fe-S cluster assembly protein DRE2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009904</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the anamorsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8D4"/>
    <dbReference type="OrthoDB" id="311633at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03115">
        <property type="entry name" value="Anamorsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anamorsin C-terminal" evidence="10">
        <location>
            <begin position="228"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site A" evidence="9">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site B" evidence="9">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 1" evidence="9">
        <location>
            <begin position="238"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 2" evidence="9">
        <location>
            <begin position="249"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="29766" checksum="E1BA50DFF99C4BAE" modified="2022-08-03" version="1">MELDGNIIVFIRLEGESPVTVFKEDESQVSNVRVLPVSSSSNLQEVVAEHLGEHDVLDGIVAFNEDVNALASDLGVLTPHIKAGGTLHLYVADVDDESKNSVLMGLMIAGFVEAEADAEISGYPGLPTARRFTSKKPAFESGSSAAIPLNSNGTKTAQPLKKWKVVSDDFDGEDDDDVIDEDTLLDDTDEVLQAAKDDCEVGKDGKRRACKNCTCGRKDEEDKPVVSDAELTQMVSSCGNCFKGDAFRCGSCPFLGKPAFKPGMEKVMLNLDDADDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C923</accession>
    <name>A0A8K1C923_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C923"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="51826" checksum="FEFA8A85853E3C44" modified="2022-08-03" version="1">MDKAAANGHLDVVKFLHGNRQEGCTTQEMDEGAANGHLDVIKSLHENRVEGCTEEALNKAACGGHLEVVRFLVEHRNEGCTGSAMEGAIQYGHLAVVQFLHEHLCCNDEITFSANNAANAGFVSVVAYLSKHFSSHLSVHEIVHCTESVHLMATIRMLEHGKVEDWTTLVLDHAASVGNLEAVQYLHTHRTEGCTANAMDGAASAGHLEVVKYLHENRSEGCTKRAMDGAAAHGAVDVLWFLREHRKEGCTSKAVGNAALKGHVDVIEFLLEHYDVPVTARALENAVSSGKVEVVDILLPQNPPDNLSKLMCLAAGKGNRQMFKYLCELTPADTKTLGQCIVEVTKTGDWHFVKFQLPKVTGSKWISSAIEEAASMGDLDIVELLLSRGKPFEPNQPFAFMNAAALGNFDLLQILETISRAEVVKDEKSRRAFLNRKKFERLTQQGRFSPDQRAKQAEEGYNSGDESDMSSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C936</accession>
    <name>A0A8K1C936_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C936"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24002">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24002:SF3">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="13"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="433" mass="46903" checksum="67736343603D805D" modified="2022-08-03" version="1">MTMLLTTTTTTTHWLRAYVLYVVSFLDLMAVSMIIPSLASYIKGMEGGTLAFGYIMSMYGFIQFFSAPIAGSLSDVYGRRRVLLACFVGASLGYLILGASWNIYLVILSRIPPALFKHSLDIIKVAVTDGQDPETRSASIGRLNAAANAGFIIGPVVGGYVSAIPNGFNYTTLLTTAIFALNYALISFFYVDHMPTKAHDDDQDATPAEKKSVHYRQLVLDTKNKLLEFKNIIHETGPAQTLLLARLLLAMAAILYRTHFSTLLEDKFGTDPKSRGFVLSYMGVLGAFGSVAVGVVTRFVRSERLVLQVSSLIYVATFLALSHATSLRAVYILLVPQVVSISMLRASSIGLQTTFVAPERVGTFMGISSSLTSVARTVSPIMSGWTYLVSVDGPAYGAALLAGLSAAMFCFSPHFNSINSIKHASNEKKSVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9L3</accession>
    <name>A0A8K1C9L3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9L3"/>
    <dbReference type="OrthoDB" id="68267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="25605" checksum="D8E7E3D12EE726B8" modified="2022-08-03" version="1">MTKTVLITGSSRGIGLALAKQYQSDGWNVIGAARNPSTAEKLQALKPYKVVQLDTSDEDSVLRAAKDLEDEAIDVIINNAGIADIYETFETMTKESMMKHFEVNTVGSFLVSRAFVPHLKAAVSKNGIAKLVQISSSLGSITLNDGVVGFPSYRVSKAALNMAHMNITHALKGENIVCATFEPGHVATDMTNYPPELKIKPSLQPWESAAGVSKVIAGLTLNDMGGYFDYLGERLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAF9</accession>
    <name>A0A8K1CAF9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAF9"/>
    <dbReference type="OrthoDB" id="66697at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="522" mass="58554" checksum="1420980AA815D672" modified="2022-08-03" version="1">MGRRGNKRKRERSQEEAVVDAALSEVNDILQGDDRSQKETWQIGKRLKKLMEEHPKMTQKQTLDAFFLWGTALARLASQNEDATLAEAAVDKFQEMHKLSGGDEAAMGPVGYSLWASALLIIATENQDREVLDQSLEKFQQAVEVDGGTTFESRFQYARALKEGADLVKFLETEAAQATGTARQTDHRSYYKRALELCEEMERIYAEEATKPKEDAKKGDGDDDDDDEDSEEDDDEDEVDPDDDVVHVDDLAEVKLLEAILHGMLEEDEDDDTVDPVACFERTFALFKRALELNSENPGVLMEMASYVGKKCKARLQIEDLHNVGWGKILSFLEEQYRIALASVDFPMTECHEICVRKDTRQEEEPEGEENTDAQVPHLLHAFGRSLVGFLIGEAAKPVAKPTLAALMKLKKNKGKAKATSSSQAAGTGHPRYIQAVEALRSAHHFHDKLGCYPLACLYAAKGYENEEQCRIWLETAETYGVLDDEFVVEDFAAFQDKPWFQKFTQPVEEIAPGAETAQVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAR3</accession>
    <name>A0A8K1CAR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAR3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="218" mass="25307" checksum="AA6E5F64D0CB5A5E" modified="2022-08-03" version="1">MTAASASIDFGQLRIRKTARKDVTLVGEILVDGFHDDPFWGCIDLHSKYPKAEKFFFKRWARIVRKTSFVVVYKDEIIGHYYITPPNDPGPTFWKLMQYGLYQLPIRFGWTLTKRTIDLLDTDTAARNLMLDQRPSSEVLDAFVIKSEWRGRGIGTHVLEEFILKDRPRLALFAHKKKVVELYEKVGFRTLDQRMVSTGHGHEYESWGMEYTAPAKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBM9</accession>
    <name>A0A8K1CBM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit STN1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Suppressor of cdc thirteen homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBM9"/>
    <dbReference type="OrthoDB" id="77828at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF33">
        <property type="entry name" value="CST COMPLEX SUBUNIT STN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41927" checksum="7C6360AAD28BECDB" modified="2022-08-03" version="1">MAMLQGGIPTDSLTWTYVKLFGRQLVEHVTDWKAIPNSHAWRRAAQSTPTRVLTKAQVMGVLVSIQMRADRVELLVDDGTGLVRAVQWTTTWVGRVVLGDLVLVEGKLNADTSWGDTPGSTRELRVLRISKVSDPNEELLQWLDVVELTTSFYAQGVASRQTSVAEARPLTQRADTTPQPKPTGWETITRRVFLECLVPEDEENAFLSRSDAAPCDATLMEVLKRLVQRQKQLTTAREQHALHITFPELLNELLREKDIPVERALHHEITRFLRQTFAKLRSVGLLALVDQETDRHVFLSFQFALAPILLAFLQGHDDGASVAEIAEHVIAQAQWRRLSFEWLECALQRLVEERKITQRPTDKRFQCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCR8</accession>
    <name>A0A8K1CCR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Triosephosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCR8"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="27360" checksum="895A9A8C29D21EBD" modified="2022-08-03" version="1">MAAVRKYVIGGNWKCNGTKQSVRELIDVLNKVEIDTEQVEVIVAPPALHLELTQQLVQKNIAVSAQNVSATGLGAYTGEIAAEQIIDFGLKWVITGHSERRAYYGETDEVVAKKTKRALDLGLNVIFCIGETLDERNADQTLEVLKRQTQALASIIDAKAWDHVVIAYEPVWAIGTGVVASPAQAQEAHKDLRVWIAENVSVDVAQKVRIIYGGSVNGKNCAELIALHDVDGFLVGGASLKPEFTTIIQSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD87</accession>
    <name>A0A8K1CD87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="2 9">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013732</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="2 9"/>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD87"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.120:FF:000035">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="38314" checksum="E6971B427206648B" modified="2022-08-03" version="1">MHGRVKSVEREQEAKKTDEDRREELTKVRMYHEVADKVLALRAQRVLAAHLLPLTSHVLLLNPEFHVIWGYRREILLSLLDKHAQSATEEAMTPEEIAKTELKLTFEAIQRHPKSYSSWFQRQWIVDKGLCPDLKKEIALCNRLLDLDERNFHCWNYRRHVCQLAGVSREDELAFATLKIEQNFSNYSALHHRSITLPKPLTREILHDEIGIVQQAVFTEPDDQSAWFYYRWLVTSMLDVVQSEPSEAVEFLDSQIQWLLELLEMESEAKWVLVTLADLQRRLSVAQTEDEASASQAKEQSRVYYKQLLSVDPDHAQYYRDMIQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD97</accession>
    <name>A0A8K1CD97_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD97"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="39313" checksum="A777404A6AB0116C" modified="2022-08-03" version="1">MATGVELNDALLRRYNVAKNLVPQEEEERDAAMTAISFHQQGDVCVTSRNDGVVSVINCLSGMITKTIFTKRYGVDLIKYTHHPDCILFSSMNDANDFRIRYHSVFDNKFLRYYSGHTNRVTSLMMHPTADEFLTASLDGTIRLWDVRCADTVALIRTDHMPVNRVCAAYDQEGVVFGVYTDDHLIRMYDARNYQEGPFAKFSLYDNSILRVLEPHLAQLQAENLNIKKLHAVDIKFSPDGNQLLVTTNRGVFLHLDAFEGHLLHMFHQHASSQTASIKLGAAYTPDGMYVTTGSEDGHVFVYRAATGELVHKLPRGHQGDVTDLQWNPQRHLLGSVGGNSTVLWTPGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDI4</accession>
    <name>A0A8K1CDI4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDI4"/>
    <dbReference type="OrthoDB" id="159388at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="518" mass="54858" checksum="28CED8669329C04A" modified="2022-08-03" version="1">MTCVPSLVCAAVANLLEGWHELPMGSFRNPPSSYHRVLMLQRLCTVTALLAAAAAVGDAVHVHIKVHHPRAATNATTATNATATNATATTSGSGSAAGNSSAWHMKPVVSIQARVQGDTPLWDATKKAYVSSYGKTFDAQYRGVLDTVNTASVEGALMYVQAEGINKREQSVECERKNKMTNIVFYEITMVQPTPAIAYYNGKHSTPEYCPFVAMDGGKCTEAGSDIPDTCKQFDGLDGLAKVGHCVGANEQTTDPRAPYPGNYWFSFPNNCVTKKWADKTDECRTEYAGGLCPFGTKPDGETCTFSYKILGYLSIDDLVGITDGTAADGTKYANFADFCKAGHVEFDAENTGKGFEVKESIAFWEDPSDPEANSDRTKQMIEKYNELAPKAKNGTMTALPVLSELTASNPPCYESSPECATAKNGCRRTLYSQICQVCESASADCVSAPATFKFPELPVPEGKKAKLESGSGSGSVDGSGTGKNTVDGKAPVPSSAITSALLSTAAVAFSAVAAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDM8</accession>
    <name>A0A8K1CDM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDM8"/>
    <dbReference type="OrthoDB" id="1739143at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425204" description="Isochorismatase-like domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25867" checksum="F6B1DD3ABBA1BE88" modified="2022-08-03" version="1">MVQLSSLAVVMCFLATMATTTSAATTIRSVATADPVDCRVGEFCVSPDPFTAITHQDVVNGLWKPRDETLKDYVLAYTSALESSKKFVLNIWPEHCIIGTPGHNIVSNVHAAALEWAKKKKMGIQYVLKGTNSFTEHYSALRAEYKLSYDPATKLNQELIDNLAKASKVAIVGEALSHCVNYSVRDLVANWPASRRKDLYVFTDCSSAVTGFESVGEEFVADMKTAGLNVIKSTEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDW8</accession>
    <name>A0A8K1CDW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Barwin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW60995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDW8"/>
    <dbReference type="OrthoDB" id="147725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001153">
        <property type="entry name" value="Barwin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044301">
        <property type="entry name" value="PR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46351">
        <property type="entry name" value="WOUND-INDUCED PROTEIN WIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46351:SF3">
        <property type="entry name" value="WOUND-INDUCED PROTEIN WIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00967">
        <property type="entry name" value="Barwin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00602">
        <property type="entry name" value="BARWIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51174">
        <property type="entry name" value="BARWIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474135" description="Barwin domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Barwin" evidence="3">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="144" mass="15561" checksum="CA2AD4DD44911E6C" modified="2022-08-03" version="1">MISWIRALASVALVAALSAPAAVEATTATYHDYGSVKPEQTFCNIQFKSPALITAYANLGSDLKCGDCVEVTNTRTKAKVVVKVVDKGGNVFDLSIRAFNAIDTDKNGYARGHMDITYRKVKCSRRLEENVVPGFRGADEEAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE56</accession>
    <name>A0A8K1CE56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE56"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="124" mass="13600" checksum="6C9864E55F1E5A97" modified="2022-08-03" version="1">MAATSNAKRNLYVGGLDRQVTEEVLYAAFVPFGAIKQVQIPTDFAARNAAPGKRHGFVEFEDADDARAAIDNMDESELFGKTLRVTIAKPERAKLGSKKPVWAEIDESKEAITPEDANDDVEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF97</accession>
    <name>A0A8K1CF97_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sepiapterin reductase</fullName>
            <ecNumber evidence="4">1.1.1.153</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012669</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sepiapterin reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.153" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF97"/>
    <dbReference type="OrthoDB" id="153074at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004757">
        <property type="term" value="F:sepiapterin reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000259">
        <property type="entry name" value="Sepiapterin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051721">
        <property type="entry name" value="Biopterin_syn/organic_redct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006393">
        <property type="entry name" value="Sepiapterin_red"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01500">
        <property type="entry name" value="sepiapter_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085:SF2">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="32206" checksum="926299C2F7F7BDBB" modified="2022-08-03" version="1">MRSVVVITGASRGYGRCLALDFAREIEQGDVDMYLWARHEADLAETKRLVHEAWQQSKGALDVATQVVDLSLQADYVPKIETLIVQLQSKSYEQVFLVHNAGSLGDLGYTNELSSPAQLSAYWELNVNSVVWFNKRFLDVFGATREELVASTAVSTKPATQATIINISSLCAIEPFATQGLYCTGKAAREMHFRVLAAEQQQPRDANSPDFSKVRVLNYAPGPMDTEMQQTLRESTTVRRDFVEMFAKMKAEGTLIPPATSSGLGVRLIVKNEFESGAHIDYYDIAPNTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFE9</accession>
    <name>A0A8K1CFE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NECAP PHear domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFE9"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13228">
        <property type="entry name" value="PHear_NECAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="6"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="22702" checksum="1B8DC88BC167F944" modified="2022-08-03" version="1">MADKGVQRVLAVINQCFAFRIPPQVSAAGHRADSWPSDPAWTGRLVINASDDEASIELRDPNTGDLFAACPIKRDGPPAVQKVVDSSRYFVLRVVDQKSGRHAFIGIAFENRSDAFDFNVAIDDFTKELMREQVAAEEALKAPAQSKDYSLKQGEKIRIKINTTRKVKDTTDDDWESSGGSGKQSSGDSDLLGFSSGSGQAASNWETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG05</accession>
    <name>A0A8K1CG05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005265</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG05"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03423">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426534" description="alpha-glucosidase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="12">
        <location>
            <begin position="34"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="992" mass="109748" checksum="3A978854B0516376" modified="2022-08-03" version="1">MLSGIGSVRLAQILFAIGCLTAQAQELIKQDDGSGLLTMLFKQPLWPETNIHYNAFNGEGWTGVPGYAMQKSSQGGNYSATDGWWEYSLKTSQLEFVFNDNNGLWDNNDNQNYKVNSAGTWALVSKITEAPKPPPPTYISGAGYAVTGVEETGNKITLQLLANPTSEPEQFGADIKELVVDITKLEDSVRVKITDKNAKRWEVPLDLYSKGGLSKESGSGGQGQQGQGNTKSNLEVTYTKNPFTVKVARKSDGYVLFDSSKLDLVFKDQYLQIGTDVQSDLNVYGLGESTRGSMRLSPGEKHTMWARDQGSMDKNLNTYSSHPFYLGLNGQGKAHGVFLLNSNGMDVTLEDGRLIYQVIGGILDFHIISGPTPSDVVTQYTSLIGRPKMMPYWSYGWHQCRWGYANVSALREVVDKYAENQLPLDVLWADIDYMNKFYDFTLDPVNFPQEAMTKLLSDVHSKDQKFVPIIDPGIPDDETDIAYKRGLELDVYIKDTTGKPFLGQVWPGPTVFPDFFHPNSTSYWEEQLERMQKMIDYDGIWIDMNELANFCPGTSCKRKEGVACPNVGSIDLITTCCLECTGDDNKWDNPPFAINNANGRDKIFNKAISASSLQHGGIRQYDSHNLYGFTESIATNAIVEKLRKKRAFVLSRSTFPGSGAHVAHWTGDNAAQWNDLQWSVTTIQNFGLFGIPMIGADICGFSGNSNMELCARWTALGAFYPFARNHNNLQSIPQETYVWPEVAAVGRKFIGMRYRLLPYLYTLGYQAHLSGTPIARPLFMEFPGDANTRSGMAVERQFMLGNALLVTPVVYRGATSITGYVPAGTWYNLFDYSHLNSTGQDAVWNVKLDDMPVYVRGGSIIPLHQAGAMTSTAARATPFDLLVALPSDGKASGQIYLDDGEDIEGVSKSTVVEFRVESGKFTSKVGLNGYKDAKTKNVSKIVVLGVSSAPKSVTVNQGKPSQDFKYDGEKQVLEIDLKEKFNIAQALTVSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG51</accession>
    <name>A0A8K1CG51_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_009628</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG51"/>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000129">
        <property type="entry name" value="Two pore calcium channel protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044581">
        <property type="entry name" value="TPC1_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46988">
        <property type="entry name" value="TWO PORE CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46988:SF2">
        <property type="entry name" value="TWO PORE CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="729"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="793"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="953"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="984"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1015"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1052"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1081"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1167"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="16">
        <location>
            <begin position="624"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="16">
        <location>
            <begin position="947"/>
            <end position="1195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW62135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1232" mass="135995" checksum="0466B9D7B45C7C09" modified="2022-08-03" version="1">MYGATEDEIAAPALRVVPRQATNDSIDTTVETLGEEVDDQHHPFREFVPIAVSFCGVVLFLRLGTIVGSLGLFYTWLVISITFVVTAFTVGSLAALATGHASARKETHLFPSIRHTVGLKTSRFIAGLCNLSFATATAYYNLAFTEVCMDFLGVHPAKYSLPWNGSWVAALVASGVNLVLALGYWRGLSLSKRTVWVAFGVITLTLGCGILFLLLPGDPLATGVSMTHLRDNRHAQRPSTTIGTVGKFFPAFTGVLAGVNLAQTIDDAPKTHVVAGVGPVRLVPSIYRGLVFALAVYFAMSLLLASCVSPEFLLRDPLVLQIVPDAMLGVPVIHMGTAVMTLFASFSNIMAGVASLVYIRTSKNSVKAGDAVPSPHIDAPAVIWTWALSQMAVLSGSVDVILPFVSTAFLLVFAVVNFTCFYVSISSPSFKSSFVLSSPWTAFAGFVLSLGMLFVQHPAAIGIVVFTSLCIAVLHYPSLFAHLVGAARDLKSNRSETRRVNEKAPLEIRTSAPVALQVIAEDTANELQLHPSGKSRVNRDAIQLAALHVRDAIHGRFQGGVYDLKAPEALKILRWLHVVKRGRIGVMAVLFGLSFFEKPSWCFYEPSCGDPTQVKTWNLPVLSQPVSTVIELSALSLLTMELVAKHRYLGSQHFFLNKWRIVQMFCLTASVVSAVLTPFLLDDIPADSDDYTPPPFSQLLRPVLLLTVSERLRSGFLSLARVAGRVVDGLLAVVVLIVLYTIGGMMIFEGTLEGATYFANFGQGSLNLMIALTTANFPDVMMPGYDQTRISSLFFISFLTIGLLLMMHLVFASIYQNYRIEVSQRALEFARQRQKALKAAFQILYDSESHAGDLPEEKKVTSKAFEALVSELLRPVFSYFLDDASSSRVPSVQVGTHVRDMNFDQFVLNVKAFVARERLKPTIHERIGQQNDVESEANWVRQRVRSRWFEHSVDGLILVNLVVILFQVQARIDGDTVTREKLELYMPIFSCIYLVEMFLKVYTFTLSGYFARRKNIYDCFVTLVIFIAEISIRVNYSDSTDLQANRIVLFLRFLRCLRLLVALQSFSVMFNVVVRLLPAFTTLYGMMGIVMMEYAAIGMLLFGGKLAEGDPRLAETAYGKANYYSNNFNDFPSALTTLFELLIVNNWFVTMDGTVAVTSAWSRLYFISFYVIGVVMVLNLAIAFIVEAFFDQMNDTKAPTAPTPIKMNGAEDNQHAVKMLPRADSVYIGSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGC7</accession>
    <name>A0A8K1CGC7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGC7"/>
    <dbReference type="OrthoDB" id="45251at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35512">
        <property type="entry name" value="OS11G0550900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35512:SF1">
        <property type="entry name" value="OS11G0550900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="23403" checksum="192C6F5818C2AB22" modified="2022-08-03" version="1">MVSWGEILLTVTAASYLLGRKELPKLGRFVGLYSGRSVGAIIRAKQEFFDATRDHEIVKLQREFQRGLNELNEIRSELTSVGNMSRPHQPVGSVESAQEKAARPAVAAAQAAAPFTPSMLKAAGGSGSSVTPLNTTSDGIRPSVASPEYIAALSDKNVQRSEVASLALAELKLAERGSYATRIESLEGGADYVAASIVDSLLLEPVGGPKPSAAAQKGKPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGE2</accession>
    <name>A0A8K1CGE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGE2"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="113"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="34919" checksum="7DBDCDCFA67F9134" modified="2022-08-03" version="1">MLRVHESLFIRTFSLIPVAMVAVITGLEYYIFMADHLIPSFANKERIVWNLIQFAALHATVALMFVSYIRVVSTDPGYVTEHTIERIRDALHSAMEASSFSFSSQSTGDGMPHCRRCKQAKPLRAHHCSFCNRCVMKMDHHCPWVANCVGEGNYKYFLLFVWYAFLALSMVVITFFGKFLRSVTLNDPQSVSDDQLSLMGLVAFVLAGSLSFCLLIFVVVHGSLVLFGSSTIECHIYGHRSPYNRGWRKNVRSVFGDEPVWHWLLPVPPVFHEDTRSELDRMEAKQLRAEQVLDDSEDGSAEDDQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGG6</accession>
    <name>A0A8K1CGG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Basal body-orientation factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGG6"/>
    <dbReference type="OrthoDB" id="441129at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14845">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING 166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14845:SF0">
        <property type="entry name" value="DUF4515 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="247"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="62988" checksum="68730274E323A37C" modified="2022-08-03" version="1">MEEGGPTERRSSVVGSTGGVDASGSLGANPATAPPTASDLFNRQVDLQKIEFLNDRVLQLQAENEALRERHDKREQETHEFVAYFQKEIQTRDKQITKLTEELAALKLSHALELEASQQAKETESQQLQQYYSNKEESFTEQLFFLKEELNQLETFKEMKETIHDKMKNLEALLTKERDGTKEQIGALERKFLEEKARLQKEHEKKIEIVKQQAKEDARNGLDADTRKIMTDNRRMGEELRFQLQMTEELEKEKTTFEAKAKKYHMEMQISKSKEEEYAAAAQKQAREIRQLRATIRDLEKQMSESVAALEREKYVLENKSEKEIEEMTLDVEGLRRLVRLKNKELRNLRRLAQTILDQRTDVEIFFLDALEHVKREIETERRRQKEQEMERYHIQMHKASGLKGLPLRFPLLSSSGDTSPAHVLPSGSRDSDSRHFSDKVDLRQLTWEDKERVLRLVFAKINGVQSYADATPQEPSPQLPPEAGRKRSQNQEVGGQGPAVYFATEPTPPTNSVSTANLRDGPAMSMSLSGLAIGSTPQPPSGRNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGY3</accession>
    <name>A0A8K1CGY3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGY3"/>
    <dbReference type="OrthoDB" id="204260at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183:SF1">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="234" mass="26506" checksum="E0527C6F5C81D654" modified="2022-08-03" version="1">MTDVPSYAALLDDLVSMQYAEREECLEETALDLVLDGDTEAFRQWLKVTPALAINARSAKTGRSFLHWASAEGHKEIVKILLDETEANMMLRTMLGGCTALHLAVTNNHRSIVFQLLSHGADVLARDKFGCAPMHYVRSVNVAKLLTQYGGRVLDYNAKRRNALQSVLLQAELDRETDCIEIDPAVTKELQKYLQTQADLEYKAKLTQIRELKQRTKAQQKAEDKRRKKTLKDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI63</accession>
    <name>A0A8K1CI63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI63"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="1">
        <location>
            <begin position="10"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="224" mass="25736" checksum="DF1D1ADAB28EF838" modified="2022-08-03" version="1">MVETKTSKRRQLTDVLLEFLEVVVHEFLYQWRVYPQEAFTKRVMYDVPVHMNRHPQLCEYVHSMLVGCREWIHDGVLEKLCIAVLAANGKIINTLVVETSWTASLLQDRSAALGRQEDDEPLPLRAIEDHFRSTLVGVTATPVVYASNRESKHAPASFRLLAHTSEDSSRPETAVNGQAPANSWVLADPFWYKRGEGKTEHELLPVKSVRDDQFPFRLHVYLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIX7</accession>
    <name>A0A8K1CIX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIX7"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="25974" checksum="F21B2D9333BFDDB0" modified="2022-08-03" version="1">MSACCPPESEPARPTSPFVGDIKQFGQTSLYVAGSATAKEDADRLGQEGYVVVIVDVTKGDYFKEDDDIKVLIGEWLIRTDYSTVLKPSIDDAIAYLKQEAQVDHILSYGYCYGAWIGARLSTDSPPRIEGHVSFHPSWLTENSTNGGPGTMEKMTEAIKVPQLLLSGSNDPAQFHPGNSVEKILKANPTIGVLSQVVDYEYVKHGWVNRGDLSDEKVKAAADDAWSRARAFFASVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJH3</accession>
    <name>A0A8K1CJH3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJH3"/>
    <dbReference type="OrthoDB" id="164705at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="31772" checksum="423BEE277990B8F9" modified="2022-08-03" version="1">MGPPARKRDGNARADANQPTASTEVEWSSPTYIRPRTRPSNLRSNVRVSSSFPLSTRSSDRGSDRGSDRSEGPSPRVTGPRGQSTRSTQTSEPDRLIGATALYSSATQEHGVDAPVRLGAFGEVRHMTLETVEFLIQVLEDRRQELCVDAPPDRVQNRKQPKPKSDRATNTHREEHKRSLNGNGKSRQDAYDRFPVETEGHGQEEWEDEPSSRLVRSRSYEALVQLESILEARHQQLMQHGTLDPNSALLAARDAPPPSPAVVDVEEQIRKLQRTLSLNTVASRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJJ8</accession>
    <name>A0A8K1CJJ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_002328</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14892">
        <property type="entry name" value="MYSc_Myo31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025939">
        <property type="entry name" value="Aida_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF845">
        <property type="entry name" value="MYOSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14186">
        <property type="entry name" value="Aida_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51911">
        <property type="entry name" value="C2_AIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="12">
        <location>
            <begin position="13"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="11">
        <location>
            <begin position="67"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="1310"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="1458"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="1588"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="1627"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="domain" description="C2 Aida-type" evidence="13">
        <location>
            <begin position="1693"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="663"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1372"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1413"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1379"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="159"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW63387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1843" mass="209325" checksum="B9921D3B15AA9A10" modified="2022-08-03" version="1">MADEPVKKRVQRREGEKVWCPDARNVWVLGTVVEDDGEKLHVLLPEDDNEQQFPVDQVHPYDPTHSLNLENIAEMDNLHQAPLLDLLRRRYLEDLIYTYTGDILISINPYKNIPMLYNFPELDSIGKLENPVPHVYSTAHGAYHAMTKDGKNQSILVSGESGAGKTEASKYIMRYLANISVIGKKAPKGAESKPAGGSSVEQCVLQSNPILEAFGNAKTIRNDNSSRFGKFIKIFYHRDGTISGATTSHFLLEKSRIVGCGESERNYHIFYQLCAGLSAAEKEALKLKNAGDYFYLNQGNCIQCPEINDKKDFKELVEAMSTIGIDADLQKTIFSLVAAVLHLGNLEFTENPKLESQIARPDDVSNLAELMQVKTSELEFALTKRTMSAGARGSVAEIALSAVESVKSRNGLAKDIFSKLFDWLVTQINASTSTITQAGASGGMNGAGTERFIGILDIFGFESLQFNSFEQLCINYTNEMLQQQFNQHVFVYEQEVYVEEGIDFSRLAFQDNGPCLDLIDKKPMGILPLLDEQAMLGRRASDENFIQKLHQTHAIQGKIPDGTTVYYSKPRFANDQFTIHHYAGEVTYNVTGFLEKNDDSLHNDLISLMHSSECEFVRKLFPVAAPAAAGAAAPGGARRLQRATGGTKMTGTMTVGRKFRDQMAELMQELRATAPSFVRCVKPNNLRFPQGWNAQLILNQLVYLGVMETVRIRRSGYPVRRTFNEFYQRYQILARQAKVSKEKRATMTDREWCEVILKHLERENWQLGHKKVFLRDSQLRTLDNEARKITNQAAIDIQKHARRMVQRKRYLIMREKVVKIQAMVRMHLAKIKYQRMRRRVTLLNALARKYVQRCKYLRIRKSTILIQSRVRGKIARRHVWYLRNAPRAATKINAHVRGYLARKQYRRQRHAASVIANAVKMRKQRAEFVLMRKAASIIAARYKGYRGRRKYQDMKKSAIVLHAVGRGFIARLKYGKKARERAVRRNKAQRQMARIIRGFLARRSYQRARKRIIMIQARVRANKVRTEYLRGREATIRSQAMIRSALVRRRLNHEKKMATRISSFGRMIVCRQRYQDDRKRIILVQSLWRMQIQRRRLKKQLGQITLLQSVWRAHYQSKVYRDTRQKAVRLQAFTRMHIARNQYVKLKAATVVAQSAVRKYLTRRTFIKSRRAVIRLQARTRGFIQRKKYKRSVGYIVLVQSLFRQRKAAKSAMSRRQAMARVMAVIRIFLSRVRLRNRTRQMFQAADAFNLTEVLHIAQEIPGMLRVRDRNNDMMSLIHVAAKNGDLNLARFVLEENSQMEDLVYGKDSAGSTPLHYASRLAHVDMVKLLAKIANRNSGGSGLQDFYGARARSASGSSISTDEPIEKLRSMSTLSNNTPSARSPSSPSRAGLPHLRGTSSSISSAASFASFSVQPGARGADPKKNGRRTLVSSTPSAGAGRRLSLSVAPVLPTTVQLQVYKEGFLKKASGNRWATKRYVVVDEVCLSYYKAPKEKIPLRIMELSDATIKRISQVDCCFEIYSPRLKCSKNPDGIVSFVADTEEEVHEWMAAIRKVPGVRVKTSIPPFQNMICIDTSLRREYMNMKNKAGFTPLHLAVQNDDDEGFEAAKVCVWLVENGADPNAFDNNGDTPLHFAVMLNRYDLVETLMKKGADPTVKNNKGLDPVEVAEEDDMKEILDPATHAVNDPLRLPLLKPPTRLPDSTYISVFLGAIAVATGPVMETPHFNLYVLDFKGSVVERSQHTPNSLIQAGGNYWWFGNTWNIQTPLEHLKEGCVAVMELRHRSLVTEENEVGCWTFFRLDLGRITSAPVTFEMYAPPVDPFSKILARIPGDSFLQADINVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL14</accession>
    <name>A0A8K1CL14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL14"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="43"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32490" checksum="F17D59887585E85A" modified="2022-08-03" version="1">MMEPEHVSEEKPLLSESSNQRTQDGAEGSSDLVAISIQDDDLLVLKVKTLSEKPIVVEILPSESVGTLKEMIKKQANAEGKFLRLIHQGKMLSDDKATLESYKIKSEDFIHCAITAVPPKAVVNQMSAPENEQEDQDDPSRRRGFDRLRDRLSREEIQALRLYFYPQLSQYISQAERVPGESSEDRIYRLEEEWMASQGPHSEFALNVVPTARIAMESQMDMNGSILAADNEGTGTEFLWGFLMGLLLGVFMLLMLLDRSVPRKQKIGLLLGVSMNFFLSVIPKAVTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL51</accession>
    <name>A0A8K1CL51_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL51"/>
    <dbReference type="OrthoDB" id="168442at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="44775" checksum="1BED8497F8D46F0A" modified="2022-08-03" version="1">MARQDRKMLRLHFEMAANCIQRTFRRNCERRIHRDVMQKSSRPMYLRAKQQSVSFRERYYLPIVRSAASVIQSTWRKYLRRKRRKQQRGDAARILCEWTRRCIRLSRWKHAASHLAQQANEMRRDQAAGKISRWMAQQLDRHHCQNAQVAASMAQQLAEMLRAAMVIQRCHRRRHGQWRGVINSVMTEMLPRSRLATHCIQRAWRCYCLKQADRKALATVVQLQEQRRVQEELHQQHSQAASRIQRAYRRLVDRRNGKLLLKRYKIFYQRELLRKQQRQVIHRYLDEQQTKRRSQHDKSAQSTNPLQPMTPLPFFLPAAVASSSSAHPSGADPIETESGSTASDDTDVVKCWSDEYQRFYLYNARTGESTWTDDATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLB7</accession>
    <name>A0A8K1CLB7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLB7"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="256" mass="27969" checksum="FADD06B4DC86FE31" modified="2022-08-03" version="1">MSSCCPPNSEPAREASPYVGSSKVFGKTCLYVAGPATTRVGVLAFPDMFGCDSGRTKEDVDRLAQEGYVVVLVDLTNGVWPTSSEEVQANLAEWMRKTDYDSVMKPSIDDAIAYLKQEAQVEDIVCYGYCLGSWVGARLSTLSPSVIKGNVSFHPSWTWENMVNGEGALEKLTDAITVPQLLLSVSNDPDAVRTGGLVEKILKEKSDIASLSEVVDFEHVKHGWVNRGDLSDEKVKIAVDEAWGRARAFIKKITTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLF2</accession>
    <name>A0A8K1CLF2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLF2"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="600" mass="69158" checksum="52E15CDB995AECFB" modified="2022-08-03" version="1">MASPSRGLFASLRRFLPSRRRAPRVVVQPTPTQPPPAAPLTNAANLLSALAASHPGDANNIPEQPVATEVRPAPPKEEEQFEDVDDEEDSEGDGEQADRVGDGVAAKPGKSKAKKKAKRRTTWVRKLLDQESAAPKDRVHRKKRKPRTDTESGLRRCHVIHTRAVDEHLKLLGCVMNFLEPLQPARRCATVNKVWAAAVAQYYTRYCTPPRPYAFLKQFMFNQEHAKNGLLRRTLEFLSVPDRIHASETSHVFQKVADTLSLAFIGSISANRFLTLISYDRINVRFPQTRKLEFDRVSIVDTARILRYMSESDDEHFVSVTELVFKRLRGIADEKQFLQLIQALFSDSISRQLERLVLSDTSLEDMHFRHLARLFYDGRFPALQHLDISKNAFSSRFMRDWSRCFHEDRFQALRALDISANEIPSHSLTSIADTLFEANCVALHALNLARNGPTRSLVRFQQLTRSHKCPSLACLQVSYAQSESEGYAFVRHVRARMSVEELRRRKQLKFEERMRAIEANNRIKACRAEARCKRQGRCLREMYDHMESEADRALRRRKRVRKSTHLHIHEEIQRLKQDKYHERVCRELERKIKGNVAISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM59</accession>
    <name>A0A8K1CM59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008256</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM59"/>
    <dbReference type="OrthoDB" id="167993at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035329">
        <property type="term" value="P:hippo signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051583">
        <property type="entry name" value="YAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616:SF8">
        <property type="entry name" value="TRANSCRIPTIONAL COACTIVATOR YORKIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616">
        <property type="entry name" value="YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="488"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="8">
        <location>
            <begin position="576"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="695"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="428"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="695"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="716"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="758" mass="83179" checksum="595664CA3D807573" modified="2022-08-03" version="1">MASEGGQHDENTHWSASHIAQSDSAHQDLSIEPSAGASMGSERGNTPHRLASTMASQNGSCRRARSVKEQQLIARGRNLLRAYQSKRSGKGETSAAMCFVPTESRVDAGSLNGIKSVWHAQTNGFDFGHEEKAPETQGTPSVSVDWHELIDQQSQSVKLSHELEGKLEQLWAVLWAESAGLLSPHTALLRGTITELMAQKREVDVQIDSATATVRKELKNGPQQTGSARLSHEEVQRLVTQETLKLQSELETARSTIAELTTKSAAHHFERNGITKGHGSNGVVRQSPLTRTDANGLNELEQEVERLHVELQEKDELLVSLRTSLEHVVQDHGKLDRDLRKARSVIERLEIEKSQMEKAASDKRTLLRRAYTVKTKQLDQLCNNIELPASWERVTDENGIVYYRQNDRACGPELEDPRVEVAAKLLGAAPASPSPQSSPRSASGRMEQGAHASARNSVASSFDSSVSCEEFSVPPDDGTKHAVDDFETPLPEGWEMRVTTAGSVFFVNRNTHITTWKDPRTLKGSKKGSGRAKRWSADAASNGGLRIEIPSARRASVGDRGVFNGEPTNSDNGSSHFDVVFEEKGPIGIHFQANVPDASATVRRLLPDMAAARTEMIQPYDRLVAVNKNSVATAPFRHVMLLLQGGLRPLTLTFVRDMLRRSNGSDSIESMTEALVEGLDEELVVDFDISDAAPDARWDDSNGQDHVDLDTRRRSSAASSVGSSVPAEDYSISDRIITNLFSMFWTSPEPVQSQVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNE7</accession>
    <name>A0A8K1CNE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNE7"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_bS18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="128"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="42212" checksum="160CFEB08D27E424" modified="2022-08-03" version="1">MVRVWLRPALAALRRSNVAVKAGAQQQQQVLALQRLGDSQCIASIRLFSSKKDKRHEKKSLHDKFDDVYEDILDVPAEVQFLSKELEAEGEDDLELDPELLKKLEEAELVEVDEEDLDAEELKRLEELLEGGDDDDEDDFLLEDDEDDEDDLLLEDDEDSELSDAEWAKKYEHELASWDDENPREIEDDRLYIEMPGYDSSLGMASEGEMSESESDGPDPFDGWKQGMAYTPEMLNWMKPKNERSPLTKGKEKPWKYFVRANHPDVVELALDVELLRLFISPTGRIRPRRFTGLTAKQQRKLARGIKVSRQLGLLPFLSRYPEPSPEQWRAMEEEDIANLMALAEADDGTTVDDDDDDEDFDDIDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNU4</accession>
    <name>A0A8K1CNU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Myosin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNU4"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF11">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44984" checksum="4AC059DD53B7698E" modified="2022-08-03" version="1">MLPIEVDAMEMEVVRPSADYAYPASPKDSMTTPGGQARMRLSSSDRSPSQRLRLSSAEEIFQKNFVGILNKRGYNVRDSSLGPLTGQEISETSTESMTSTSSSISSVILSLREPNHGQGPLHIAVRKGDLQVLDALLENECADEMINLQDNNGNTALHFACGSWRRPQCASIVGRLLATGADVNMKNKRGLTPIAVHMLTLHVDLPAVIAQLLESGADPNTEIDGETLLHIAVRRNLSTICGGLVAFGASLTALNLDGLMCYEAAPTRLKHVMINHIIHAPPFLSPNQRSRCMRCGSGLLSTKRVFVNFLKRILHVRINSHQSNCYHCGLLFCSQCLQHTSVADTLPASFTRSRVDDLSKVKTCPLCEGVIKERLQKLSMNMRPTDERSGRSIDERSGSTVRASSMRFGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNW6</accession>
    <name>A0A8K1CNW6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNW6"/>
    <dbReference type="OrthoDB" id="105915at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="97" mass="10721" checksum="F2943B177A7BCA7E" modified="2022-08-03" version="1">MLGRVVATASRAAFAPLTLSNAAVNASVRRPVAPFNLTSVTDAFAHLRVVEEPLSSNSIAMELLNRNARRPKKANHGKRPCSNFARRQKRLSRRNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP40</accession>
    <name>A0A8K1CP40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012263</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP40"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="212"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="107"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="40130" checksum="8373F08B71BAB0CB" modified="2022-08-03" version="1">MTDPLAGARLLYAAAHDDVDSESEGSRMAVPLSARHLYPMNMTVDFTKLRANALRRYMAHHGIQELPGSSKEQLAIVVARHFNDECKLTDEETSIAAFLSYIKGSHVPDSDGSDSDVSGARSNRFTGAKDVEMRCSNEAMEEEDDDSDSDDEENSLDDETSSDSLPTKRRKSSTGGYGHTLPSSRSRSVTKSSSSSSSTQHNKKNKKKRKTRLYCVCKGSSFGDMIACDNKTCVDRSNWFHMSCVGLDPRRDPPETWYCPSCQDNEAADIPENQYRKPVASVTYGDMISHALTVLPDGKGTFKEICDFVEKQYESQLNWKLESDQRKSPVWKSSVRKILFSNVRFRKHPDDKGLFCLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ19</accession>
    <name>A0A8K1CQ19_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ19"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF252">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="236"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="325"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="49231" checksum="8981C7BE9C6427E7" modified="2022-08-03" version="1">MALPSPPTPTSTPTLALTYFDMPGRARVLRRALALGGVRFEDRALSRDQIAALKPTLPYGMVPVLTLLPDGLVVAESQAILRYIGRMTGLYPPFKEDPLAAALVDEVLDSFDDLNERLLIPTYQEDDPEKQKALRLKLVDGALRCALELLDKRLEQLQNLPFFRDASRLFVHELVAWDYAIKFKSGGLDHIPATFIDQFKTIVAIHGKVEKATSVAPAPAVTPSGPRLPAKLKLVTLADEGASAALGRAVAVQLALRIAGLAFEDQRLSREEFEKQKHAFPNAQLPVLIVVASEGHTEEIVLAQSFAMLRYIGTLGGLYPAGDDDARRALKIDELLSHMAELYFFFDPVYQNLRPDETTGIHQALAEDVVPESLEALEKRLTQWSSKGENASPFALGGDTLTVVDLAVFALVEMLTSDAVAYIPNAIVAPYKRILCAHETVRQYPLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQE1</accession>
    <name>A0A8K1CQE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inositol oxygenase</fullName>
            <ecNumber evidence="4">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_014103</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQE1"/>
    <dbReference type="OrthoDB" id="5151075at2759"/>
    <dbReference type="UniPathway" id="UPA00111">
        <property type="reaction ID" value="UER00527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050113">
        <property type="term" value="F:inositol oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00257">
        <property type="entry name" value="beta-trefoil_FSCN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW66791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="571" mass="64754" checksum="0108126ECEF5CF64" modified="2022-08-03" version="1">MSMSRSRSMRLGEQSVDVTEVLAAPTAKFRLEFTHDVRAKEMRWVLFTSVKRGAVGKLIFTLEKDGSSAHVKSIAINKEWRGYGLARILYLACISTLAELKVQELNLEAEEDSKRHGKLVGLYRSWGFQEIPDAKILFLYNDNECFRKVPMTLSFRARDFFPSQPQKDTWFCMLTLKTSDGTCLVAAENGAIQARKEKTADALWQTLLGRNGEIFLRSAHGKFLCVEDSGTVLADRPWNSTWETFQVVPYHDELDVFEEPVPSNNDQAKHAIGGVALKDFHGSYLCIDSNEHKVVSSSVPVPWDGGDIMSLVCDKTDSTPLYAKIMRKYQTLEFVKKQIEKHSAFNHASMSILDAYQALMVLTGDSEAPAQSWLLHHMLATAENAREDGHPDWFQLVVFLRGFGMLFLLWADDENGMLRSISANEWMVSNSTWVVGHAIPDQIEFPELNVLNADHCSAEKNPSSSAESGMHSVFLPWTPDEYLYRVLDFNKTSLPSEAVQALRFWSLRVWHRGGCYEGLCVPQDADTKEWLSAISNYTFASKEKMKNVSPETLMPYYIGLAHKYLPEQLQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY7</accession>
    <name>A0A8K1CQY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY7"/>
    <dbReference type="OrthoDB" id="75107at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990837">
        <property type="term" value="F:sequence-specific double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053031">
        <property type="entry name" value="Cuticle_assoc_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34396:SF25">
        <property type="entry name" value="BOUNDARY ELEMENT ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34396">
        <property type="entry name" value="OS03G0264950 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="953"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="959"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="995" mass="109051" checksum="D4529C3E3349CC87" modified="2022-08-03" version="1">MGRGRTMDEWVHFEKIPDEGRVPNSSYWYVHCRHCVRGFEQKQLVNAPTRITGRRSAMRAHLKVCPMYSTQYKMEQRALAAAAAAAAATAAAEARATVPLTNPVPAAAADETSTLVAAPVAVPTIAVTKLEGSVGEKRKRRGDEVEVSGPRGGRGKHCMMEEWDHFIRLQDEGYIGKSNFFFAVCRYCHKEYEEASEEKKAEMLPPEKLVGRREKMRKHLSLCPYFKGELPPLERRAAIAASGSGPSAYLSVNTPEGIKIVPTSVLMTGSPVDASALGLTGATSTPASVTGATTPTPAVPTATTPVTTPGRGPPSRLALDEWQFFTRLQRKPDSAYYFARCNFCQQAYENAPEALKGSMTPAIVMGRKSNMQTHLARCPYLPNDTTIFGKTSAAALSGLESMFPGAKRLKSGITVDTTPLFGAIMEVTIQHRLPFDWVDSASAKKLFKLGLPALPEVDALLPTADTLRGQVLDEYYHNILSVELEKLKQTVSFSTSEPGQSVSASWPVVLKVSAVKAQKNEALPSLDCTLSTEDASVPILYLHDRKTVIEDDLVTGISDDVSLSYYHGLDVARWIDTQLRQALNDEQVTTGVVVLPPSPVNQRAVGVLRSRWPNVVFAWNFEDLVTYCLLKVLQDSKVIAIADSILPLWDNEEVKELLKSIAEPTADFAAFADFAQAVLSEVSVALPELLGTVDRDTLSQVSVLLRAFAAVNGSLITGRVSFADALTHLGTLYHASAEFPSVREALEAVWAEFEQPLCVLGNAMHPHYRMRSLRLTDVTKLSALSDSGVTYFTQFFSHKPVSLRGDLTAYLHTSQHVFSDAFISEFPVVDDYYRYLSDNYGELAALMRLTSSFSAMGSSVKAAHEDNAPFDATLYTEDERHKLATLEERWSLHQPSDKDSITVEAQDATTLIGGWMAKLEGDLQTRLVDFSILENKESTEDSDSEVLVADESALLPLPSQATDDLTTYPSTSLKGPRSKKIRLDELFSTEQAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR14</accession>
    <name>A0A8K1CR14_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR14"/>
    <dbReference type="OrthoDB" id="67322at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="177" mass="19946" checksum="B74DC0C2B98FE789" modified="2022-08-03" version="1">MESRLSATSNSIKNMKISMESERMFNEMDEELSPASPTRDIRSRLSSRASMSPGGSGGPSSSSRVSVKDQLYALECKVQSHEDTIQKLMSIHQADKTILLSKIEEITERMGEELHKLRVDYQKKLNTASEEIERLNKCLNVQRGHITTLQEQCQSLHKHVVQVDDDVTKLATEVLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR40</accession>
    <name>A0A8K1CR40_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR40"/>
    <dbReference type="OrthoDB" id="167565at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="123" mass="13844" checksum="E661E7BAF137B5B3" modified="2022-08-03" version="1">MWITKTQWKAFKAWMTRTNNLLIILGLFVLDIRDIYYKIAWLGPYETFSFRACSTSDFNPNPLVIVDAQQPTPGASVEFGSGWPSFLARCERLHALGANKGPFFLSALGVNCILRGATQLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG0</accession>
    <name>A0A8K1CRG0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_007857</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG0"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="411"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="17">
        <location>
            <begin position="47"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW68185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="55673" checksum="15629D0EFF61CA8E" modified="2022-08-03" version="1">MTVSTPKSSSPSSAFNGAASPTAQKQAEEAKDVNDTSVYASLRVNSILYVCVAFALLLPMQFGWSVSQVNLSTFNNQADCDARPVRPGTCLMFPGHSKGDWMWVVNTWIVGGMIGSLGSGQVSDRFGRKKAMMTIAAIMIVGGVIQAASSSVPVFTVGRFISGLASGASTAVPSGYINEISPPHLRNRLGANFQAAVSLGIMLVCCTFFFANTSSGWRYIGGFPIVIGGAFLVGAVSFLVESPAWLLTTGRKEEAERELARLFGEENVDVALSWLLSARDESVELEEHGRSIKDETSSEGSTVQENPWKLLFSPDYRMQTIVAIVVALCQQLTGINAVFFYSSSFFKDAGLDDDRIGNVIVNFFAFFPSFFAGVLSTRFGNRKMMIAGHGVMLAAAVGMTVALLVESSVASIVFTAIYVAAFSVTLGPLVFVIVSAVFPSSLRATGASICLFANWCGSLTVGIGYPYVADALEDLGFLPFIVLLVLFGLVMIKFLPETAGKTDDEILAIFRSKRKAKTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRJ8</accession>
    <name>A0A8K1CRJ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRJ8"/>
    <dbReference type="OrthoDB" id="167718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF12">
        <property type="entry name" value="EUKARYOTIC INITIATION FACTOR 4B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="688"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="642"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="765" mass="85269" checksum="5701823F74469A51" modified="2022-08-03" version="1">MEHEAVYARILTRVERAELHETCQKVADQEAKLVLRRIRGAEGMLQNAVDVTAATKRVEVSQKRKLSTKNVRLLNEIAEIQRRVSKRVDLLLKNAGVCKVALIACESPQKRQADDDSTDALSSHTPCKMVSSNVSKAKLMDFNSDGCCVEGPTIVTTSSVVVDDLSPMELDVLDSDSDSSGPTCLQVARQLEKQSIHSQIMQLPALIRRFKREFSLSSVEDWIPVFASIVSMLTKLSISDGTRIQSSIDELEQVAVDISSFTGESSFAVFHSRLRSFSNSIEQARHRTTSLDSLWDCVTKLQAESSAAGDTRTLEATDEPFQILQELLQPHYWQWSESDSEKTRQSVQFLIDYIQGIPTHTNSTQARQKQLETWQKALETVCQSTIMSGFERILARVGGDALRDYCSSAIEDELNNLKTKMQSCLETVEKAIEVQDAIQKLNVPLSEDNVATFASIQKEYQQFSRDLLTFMDEQKKIPVETASTHKATRRMRTDSVASSVDTNLSALGESQRLAKLVSKIQHRLTKKHTNQTWILKNIRDMQIIASIVKTFEPEKPQRKEIVLALDHFISAVLIFPTTQTGDLAKLTVVLDELSLATQEIGDFAKSSRTFVISKLESSRQPSYSQDSNQHHQSVGADAIDSNATENASDESSEPSAKRQRIDDDNVTIKVERQQQDHASPMAALSSVHDVYVTELPWGTTQSNVESYFSVLGSIVSVRMPTMDDGNTVGVAMIRFATAEGMNAALRMDGYHFQGKPIRVALPKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRP7</accession>
    <name>A0A8K1CRP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRP7"/>
    <dbReference type="OrthoDB" id="71407at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STI1" evidence="2">
        <location>
            <begin position="158"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="2">
        <location>
            <begin position="265"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="36815" checksum="CB749D8940637502" modified="2022-08-03" version="1">MKTQRQIDTRSAALNEDEEPPLLLEDHEQDNQLHEMTSNDENEASIMDEMMAIAQQAKATKRKQQEKERNSKAFGSGLKKGFFNAAPKKTSKATASQTTGNQRLDVDDTKRRNERLQIVNASDSKKTANQSRDDSFVFPEVQAALESMNHLNPNEWMNEAFFEKISKHPNLLQALQNPRFTQAISDLQKDPKAAMLKYQKDEAVSTMLRDFLGFLGDHFEQLDKQMKQNEEPPSSPAVPAPPAIVDLDETRREAIANMPRSSSEEAQVQQILQRPELLEALSDASLMDSLRHAREDPRELHRLRTDPVLGAKLRLLVDAKLVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS76</accession>
    <name>A0A8K1CS76_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS76"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="548" mass="60293" checksum="F33C427085C04A30" modified="2022-08-03" version="1">MGRTPRSSLKKHDAAAESRASKARRQRTTTQIRKDKRRETVQTKRRRLMSNDDIAVTGRSIAELMTILRGSDASHQEQYDVLREVRALLSAHENDYETVEQIIESGIVPVLVELLEQASPLATSTRTGGEVYKEILWCLTNIASGQYEHTKLVLPAVPRLLQFLEGSNATLAEHSAWVLGNIAADCEEFRQQLIKNGAVVPLTKQLTNVAEPELAKTSAWALSNIARGHETSAKAFIDAGIVPIVVTGLQQGTPKSFTEGIVVEIAWLLSFLTAREEEYLKLWLENGLIDCLLPYFATTNELLLTPILRVFGNICCGSMDHHTDEWQMPFVHHLLRSDSVFLPKLLEFIQPNVGASHAHLTAESAWVLSNLATLDVQVVDLLLHAGFLPLLVQHFHTGSYEVRREVAFVVTNVALTSPAHLEQVLSFDVLKGFLQLLSAADVAVVGNSLRLIENVLRVAPNGVSVIESHGGIEALENVQFQSQEAHLSQWAEALVNEFYGENYGINSPPSLAATGGALPEFSFQLPPPAPDAGRGRGAHMTMPAWKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSQ3</accession>
    <name>A0A8K1CSQ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSQ3"/>
    <dbReference type="OrthoDB" id="74787at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="376" mass="42141" checksum="637916D1C23FFBC1" modified="2022-08-03" version="1">MTTGNGTYMETVSLNDDEPVTIDTLEAQTPRNNGSAVKITKYTGLPTPISEIEDEDDANEDIVVVVDHSKHEKPRPTPPSLPPLRVAGLSKQFDDEPEYVDPTLFSPEVSRHSMEQAHRRARNLETELKEMMILEPGTAQQKPAKITPGEALSVISSAFLSSITRARQLVTGQETEYDLLSGSSPSSKVDDLDTDGDGLQLSPDAEKGDGKHFQTPRVRPALKRISAYSTIDKEKKPTQLKKKKIQWDEDVLDQDEEFVEDEEDGESEAFVNGGSTALSERQPTPRPRTRKKRKKLIRTVMRRLTPREKEELYKERPDLMIVPNWAQKYREEMSEGDSARWGFWLLTIIGTLVILLIILILLIAHDKGASAASSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTV4</accession>
    <name>A0A8K1CTV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_007855</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTV4"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="424"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="15">
        <location>
            <begin position="63"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW68183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="58169" checksum="329BE1DC98912E02" modified="2022-08-03" version="1">MPADEQRILPTLRPSISIPIADDDSPTAYAQVLTPLATAVPIAQDEAVESPKIVQVKKLVYTSAYLAMMQAMLYDWSLSQVNYVKFNNKADCERRPIAPGTCLMFPGHTSTEWIFVVNSWTAGGIFGGLLCGLFSDRLGRKRTSTLNCVLMSVGAIIQAASPSLPVFCVGRFITGLATGTATATCNGYVSVILPPHLRSVLGSVYAVAIGSGVVLVGLTPFFAATSSGWRYVAAFPIVLAVVFLSLSPKHLVESPTWLMTHGHHDEAIQVLIQLYGEENVDLALSWIRRPAPEPTNSTPSPVLHAPLQALHDIQQAAPAKMSAIQSLVSKQHRKKLILAIAIALTMQFSGINAVFFYSLSMFKDAGIDDSRIGSLIVNLFNLLPALVAGAVVKRIGNRLSIIGGPSGMLLSAISLTVARVYHVYALSIVFISTYVIAFTLCLDAVGFAVGTSLFPHSLRATGTSIMMFINWCGAFTIGVGYPFLSSSLNEYAFVPFIGTLTLFISFFYAFLPDTTGKTPAEIQELFAYEHVKKDESSSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV16</accession>
    <name>A0A8K1CV16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Apyrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the apyrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV16"/>
    <dbReference type="OrthoDB" id="25028at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030166">
        <property type="term" value="P:proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.100:FF:000001">
        <property type="entry name" value="Soluble calcium-activated nucleotidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.100">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009283">
        <property type="entry name" value="Apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036258">
        <property type="entry name" value="Apyrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13023">
        <property type="entry name" value="APYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13023:SF3">
        <property type="entry name" value="SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06079">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101887">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR609283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="49183" checksum="E21A81D0D078DEDA" modified="2022-08-03" version="1">MLPLLVGAPEKKRKSSSIDPNVMWTDSRAGPSSAASASAALTRNRAFLLMLVLMVFMFFSMSSTTLLQKATESTTRSRLRGPTEDGVVVTGTNGNSHVMTFPEAMAAAAATQHPRAPSDVTKATRPDSFGIVVVADLDKKSKDTTSKKPLFFSYLQHGTLKIARRGEREEYSVEWGETQKFSTTMNEAGRGFELSELAWFNGKLLSFDDRTGIVYRLKNFDVGKRLQAIPEHIIMEGDGVASKGQKHEWATVKDEELYMGSVGKEYTDNDGNLVGDSNLWVAVMDKQGDVRHEDWTSNFARVRKALGADYPGYVVHEAIEWSSVHRKWFILPRRVSKEAYNDELDERRGSNKLVIASEDFSSIEVLEVGKITPLRGFSSFKFVPRSDDSVIVAIKSVEIEAEQSQTSFLTVFDIRGNVLLEETELPGGHKFEGVAFSHDWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV79</accession>
    <name>A0A8K1CV79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV79"/>
    <dbReference type="OrthoDB" id="163036at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429641" description="PX domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="2"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="43133" checksum="09703036BF711578" modified="2022-08-03" version="1">MSGVVHVLSATITSALAIKPSTVYVLRVENTATQDVWHIRRCFSEFCDLREKMVVLIDGQRGAPQVKEPPMNTGGGGSNPSTPSPTTLLQRRLNALYPIKETTFSPRVPSHGSTTSSASSTGSGYSVSATPSLDVHERFPYLYSKFPRRQFFGSRTKKVIEHRTVALNQFIQEALWFIREAKTHHHIAMYFSLMTQLETFFDCARHARPATNSFLNTPTEATAPYMLPEVNLVAKNAHEALLARAMATHGFWRPATELSTASNNQIGLYDDDDESDEEADDYEERKVLKKTISCFMEREVRERSLPPAMTRASERDRRVSAAEAWAARVEIAGIPPAAAAALHRRREDNQNPARLFQQQSMPARFSSKASNQESVQFERRQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVJ1</accession>
    <name>A0A8K1CVJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVJ1"/>
    <dbReference type="OrthoDB" id="93327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="27714" checksum="3C54AF710F34FFEB" modified="2022-08-03" version="1">MVRNVHEMINEVLNMFPNLRVSLNSAVSGRHSSLDQLVTKLQIAWQDFFDFLWLPGHVAEWFRRHRDDETKPATNGPDLSEVLSKLTSMNSKMDRHHEAILKAMATEAQRRVPRCWTIECVSDYSLIVKIRSELTGKCYHEPIEIIKAPEFFEKYKKHIQIGLNVLVGLLPGTFANGILDGLQPELDKYVAVVSVTKDLDLQRGDEIDMESTCSLPPDSIDAMLQDLLQIKFQDYANKNFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW09</accession>
    <name>A0A8K1CW09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor-like protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_001797</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW09"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04157">
        <property type="entry name" value="Arl6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000457">
        <property type="entry name" value="ADP-ribosylation factor-like protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041839">
        <property type="entry name" value="Arl6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 16 18" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="15" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="9 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW69641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="188" mass="21240" checksum="862D84555B7EC2F0" modified="2022-08-03" version="1">MGLFKQLANALGMKKTEVRILVVGLDNSGKTTLVNHLKPKKSQSREVVPTIGFQVEEFTKSNLNFTVFDMSGQSRYRSLWENYYSDVQAVIYVLDSTDSIRMCVAKDELEQLLEHKELAGKKIPILFFANKMDLPNALTPVECMEQLELEKLPGKTWHITASNAVTGRGVEEGIAWLAEQFSRAKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAX8</accession>
    <name>A0A8K1FAX8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAX8"/>
    <dbReference type="OrthoDB" id="69756at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="30913" checksum="D98B8882BBCFD597" modified="2022-08-03" version="1">MERVSADARLPLHPRKAQELFFELIEAGQYQQTSTGPTQKSIPDRLGRFQAFYATGIRDLKRGRWVRRSPTQEVEASSEADGLVYFRLCQEGKSIEILQRTDPSTWESNEEESDRQNHLALVSRITLQSISRLWLLAGSTFRLEINSTVEHSESETTKAEGKPNQDEVIASNSNVFEVDTDTVLRQTILVLLSGRYALDLKSSAQRAKTEGVLWQALRLRLFELSEMLPFHQALQLVEDAFQVISVRESECELPDMKTRFLLHSDTSIDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB42</accession>
    <name>A0A8K1FB42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Myb-like DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB42"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000016">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="40"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="85"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="89"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="136"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="48795" checksum="F4758EB8696A7DD4" modified="2022-08-03" version="1">MADVIAKRERPDDDDVTLDGLDPSDAQRVKTAEEGAAGKRWTPEQDDALRAAVEEFGQKNWKSIATRVPGRNHAQCLQRWNKVLKPGLVKGHWGHEEDLALQEMVLQGCHSWSEVAAQIPGRTAKQCRERWRNHLDPSINRAPFTPEEDNIIQQAYERLDNRWTQIAELLPGRTEDAIKARWKTLNPNQKTPFGPGRPRLKQRNADLDIAKMQRPMVDGVQPQAQYVYQPMYDTNGALLPGAVPAPMYASAAPASSEYPEPSIEPLGDDFHDSITEKDVALLKEFLRSRSNSLLSFGSSKGMGSIADMSPDELLASGELDEMLRAVSLVNEGSVTRSSLGSLRLSNSFSNAQSLSEALASMDSQGKHVFQELIEELRAGGVIAEAGQVPNDPNVYTHNANGQPTTISIDQDYTQAAADTDDDLDDLLDPNLMKAFRKGKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD6</accession>
    <name>A0A8K1FDD6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD6"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="2"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="725" mass="80725" checksum="FDF99223654FA0A0" modified="2022-08-03" version="1">MTPTLQALPSEILRGIIAWLTGFDRLRLAHTSARFYRELLVDASHWSDAHDVTASQAKRAYVQASSLQFPAQTRAGFASGERGACVPVLRFFPGRKYGRPTSELFLPLSPRFFSIDLWFSLLPSAQETDVLPGGVLLGAQSVRLQDAFAYADYHQPFVWVDPSLTLSCSILDDNVEAHEAVVKPTLRTQQWYHLALTFDNGVQSVYLNGELLHTRHGDLHRDWRSLYYMQLGSGCVTGHCIGLDTAASATGWYGFHGVVDNFRVWAEALGVDDVRRLAQGHGLTASTPLSSLEECNRADWCGPVKRVRCSRPYEQVCILDTKGLCGLHIVTCAHLGVVYLKADVDYIVSCSYREELFALEKDAVTHYSWRRTMKLAKASAQRLKAVIVEYDVLCSTRIGQASASMQKAPVSASAQRQPAQDKPPSVSTMFLSDVRSMLKDLQQDSTGKPWIVKDRLQSLLQGLPAQMVDRMTGGAEPTASGGKEQSEDAMYLEKQLASATAEMQRMKELKAAAQQERRENEAEKGNSVRDKYLDKLNLLKAKANARQQQPQADASDFAGSSASSTQSVSAEEAKTRGLTTWLVNEGANELMSYSDLRGLFRIVIPPLSPLQDEEFRLFTKEMEGQFDVFMTKDDQKRFPDPAPILAICEQLELKPLDLMIVARHGATLKAARAAGANACHYMPEENAIPNHTADHHLTTLREFQHLIEDFNGISYRSRTHIESMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEG1</accession>
    <name>A0A8K1FEG1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006607</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEG1"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="8">
        <location>
            <begin position="249"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="717" mass="80643" checksum="BFF893ED7400FBA9" modified="2022-08-03" version="1">MAKKNAKAKEAAAATSGSDVDKKPAASKPVAKEASKKSSSSVLFLVLPVLVALVGGLYTTFVVPPTDSALATTTQSAVVNTSVTVDPLKKYPQLTNKYASQMIQIETQQLLTPHTAACPAFEIVGDLMHVEDAMDKTAEQLRQEQLVFLMLNGQNEGLYVKWQAKDACLRELALFAGEKLGADVDVLANGVKLFTQMGLPITSVEQFDQEAGRIAHVLLDFQIWVWPGIKVGHVFEVEGTTVKTLSMRPKVFGVEGFFNEEEAQEIMRQGIDRLERSPVDSAEAVDGYHSDRTSFTAFLHDNEFTRDFRARTAKLTRLPSPSFVERLQLVRYEKGQFFRKHEDYFDSKQFLPKKEIANEDYKLWCTWAVAKIQELVTAGADVPADFLEGGKMYPNYEDKVAFQHAILEAFMEDAKEVDFFREHADVEWGEWISSNLENGARDIVDPLLRDKGYLLPHIIKSWEKRAGFKELKFTIPKRPVSGVTHYFRWIRWVKEHIQNLLDQDASLVPAEFKPEGDMYPTYHISYQNRILKYVLEDHTEEELAAKFGEEWAKWLIANKDSSDVLWQALKTSSEIFDLVVESFTKRAGEHFAYSKPTHLQHFEPNRFVTVFLYLNECLEGGETVFPYSKERLVTNIEREGMAECSEGLAVPPVKLTAAMFYAQSPENFPDPASLHGGCPPARGIKYGSNSFAWNADADEGANAWGLGSDLKADPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEU0</accession>
    <name>A0A8K1FEU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEU0"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477778" description="Amidase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="179"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="616" mass="66484" checksum="03DD6FFFB2F0C0AD" modified="2022-08-03" version="1">MTRGATVVVALVAVSAALLLLGEDARLPEYDVLTQPKNERDYDLVDLDAPRLVGRSLEFLAFAMRTPVMGRIISKVTYRNNNMLEVRRVAALIPDMPVYYPIVKPPQSSLDQETPLDLVAFSQQNLNVKTTTTNGFKHWSISDYTSRYASGELSPAQVAKAVLAAARELELGEIPSCIFIETFDDELMAAARASATRYAEGKPLGVLDGIPVAIKDEIEIGGHEMSHGTTFLGELLGKAAKDPASIARLRAAGAMIVGRTNMHQLGGGVTGYNNHYHTPRNPYNQHHYPGGSSSGSAVAVASGIVPLALGADAGGSTRIPAALCGVVGIKPTFLRVPPLGVSCPSLSNVGPIAGNVRDAAIAYAIMSGGHENLPHSLPQPAVQLHAFDSSSSLKGLKIGYFDSYLNHSSPEVAAAVRQSMKKLEALGAELVETKLEYLLAIHYAHSVTVSSELAQRMDKFHSRLSEAGPEVQFVVGFARHYSAMDFIAAQRMRGFAMRQLQEKVFSQVDVFVTPTTGITAPEIPLDALERGELDAQQLSDIFRFTVYGNLAGTPGVAVPIGYDTQGLPISLQIQSAHWQEDVMLRVARATEVLYEETQRQPQVYFSIIDEAKKHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEV8</accession>
    <name>A0A8K1FEV8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEV8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="274" mass="31226" checksum="D619A8AD28D882A8" modified="2022-08-03" version="1">MLEVDDDPKTLCALLDALDEALEAHTDGLDDGNEESHQCTCSHNRTAKKKRGISSFARQRQQILDLQQEIQCLEGVLAAQKQHRAISLVHSERQKLWKAIALRQRRAQERAEAECAALRGYMAARFRLEDGNARAILAGAGYQVPRPLDLDVLRLPVDEAFARLHHLSQHTHVAFAAQCFSDGSQNFNHVEMMSNSTEETVIDCRNAWVLPFSLDHVHRSLWTYMNRMSMMIPDPDYQTDQLTTDDSVVNAYFFQAKMNDPAFQARDVTKNFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF03</accession>
    <name>A0A8K1FF03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013573</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF03"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44042">
        <property type="entry name" value="DUPLICATED HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="44081" checksum="707F0B4060D7EB03" modified="2022-08-03" version="1">MKASSGFMTHSGRTAQPRVDTMATAPSDGPPWTADEHQRFLDGLEKYGCGQSTSVFAAWHAITAVVRTRTLPEVKAHANHYYLQLQMINTQKRKEYLTMQHIDTRWTPQEDAALEAMLADHSDRVSFPWEELAARFRNKSARDLRDRYQKLCYDVARIEAGQHVIMHLGQQPRKTSQHNGIPLSTPRSQQSASETHSVDCNLMLTTAETELLLRALEQVPVPPRASPDVLTVVASAVAALACAKNKRPPQRTQPQFTLEDARNALEDTILMEPRDAEQVLEMLARDLHVLPTQTQYKLEDTMHGSHVNMTPRLASNLSPSASAYYLTSPPGLAKEDTRSAEDLLTLRTSPVSRDGFLQRSHADTVSNSVFSFTPSSLAHRPSPPHDHDGALGYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFM7</accession>
    <name>A0A8K1FFM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFM7"/>
    <dbReference type="OrthoDB" id="75885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="35483" checksum="6985ED19FC8811CD" modified="2022-08-03" version="1">MSVVMLPSIHSATSALSQLKTDNAYLLPPRPDEDPARRAKTNSERGKEFRAKRKKYEGELETAVYRLRAQVADLTLSRSVWERKLLETRQCETGSLVRLIRQYFDMFRFGLRDSTHLAGTKRTLMPSDPTADHIRQQELFIRQVMDQNVSVGDQAGPEASIAQWRMYTISHDSLRNEPYRIVTLGSEELPVVEVYSKVRARISRNTFRFMFPSALGREDLVQKFLHREVVYDSVFRFQFTEEGKIAVESADIGFVDGLLAAGFSLNEITELMQLSVVTPQCMIPEPVEVEEPSPSTSKLNVGFLLTADETEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGI1</accession>
    <name>A0A8K1FGI1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGI1"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1138" mass="123323" checksum="336904CEA3EA4DDE" modified="2022-08-03" version="1">MDKDHEVEEPLLPVGASPVKRRAPWHQRHRKALLVLGGVSAVLLVALVIVQTQIHRIATNAIAATEMSIQRMELTQPLAHSLTLSLALLIQSPSFFTAELAATNFTIRYQEGVVGVFAAPSMTVKQGRNLQQFANTSLEIANRTTWDAFARDLMQNPALTYEINGQLALRVKILGGLIHLSASDIALVKTMSSDGMNGLKQMEIADIQMTNSTQKQVIATIKTCLYNPSVIVLRPVGRICMNAHYPRIGSASHVASLLTNGVADIAVDRNSASHPYCASRSTDKKDMRSGYNLLELTGEMLSTNPEAISALISKYLSNTPADLEVVPCHPQATTVDIFNIAMQDLKIPTILPPRVEPLVGKMFFQSIRLDAPRKEDENDVLGLSTGVTVEASSPLGPNSALMLKEIHMTVGLYAVHEQHELFLGNLTTLKVDITNGKLVETSNISVDCVAQLKFDSHGKPFGSFVRESVVQNEVKLHLKGSMNVIAKGALGHLSLTGLPLDVATQLQGMDNLQRVTIDEFELPGKAVKPRGEALSTKISIWNPSLFSVSIGVVTMQLNLAEGSSSDRYLGELTGNMVLHPGKNKLHMKGELKPHLDAQGRVSDGVAQFFSKYLRGDESRVSVIIQGVQYPDCTWMNDALVGLVITTPFPGVAPGFQLISNLQMRELDVSLAPRPANIGSPASNTVMKVRTDLTATVKMPDTISIPISIANVSVNLRLEDEGMSVMGALTSDREVCEFDQAKDGYFRLDMHKFYPISFNHPSEAGAMASFVKYLLTQSGNVTLRLVSHADADEGAFPYVNTRMGMLPLLDIPIIGAPQLPAMNSFRDPPIKILKVDILGGSDSAMYLMMEFEIRNPSVVKTALGALSLEVFSSQAKMGTATIADFKLECCGKATVLKGTFLFQPAPTDRLASSKFLSNFVCGYFTNGTAQEISIAGTKESTPLDLLQPALAALEMPTQLPTLADLFPSTPTLVTSSLLYTPSIIHLDRIPTSLMLQNPFSENITVIGVDLLLYPCEVQAKVNDTLVCHSYYSVPLARFAPEKFDPIFIPANSDGCHSCCQGANCEKKTAPLCPNASIGQCMTANVQGLISAEAIAAIFHTATTGLLMKVNGTIEAAIGAYNSELFYRQEGLLVTMAKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH32</accession>
    <name>A0A8K1FH32_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH32"/>
    <dbReference type="OrthoDB" id="10647759at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="31806" checksum="AEF24DCE7BDD2CA1" modified="2022-08-03" version="1">MARRTPARSSEEEEDVVSNSESESVGSSGSGGSSDDEASGEDESTSDEEEDEEDKAVAKHALVENDLMEVRKMIEEMERIKARLQFRLSRERENGSISSPPTRRASVEDIIVPPTVSAAVQTNWDMTKMFEVEKVVSSPEIPPPQVAPINKTAQLSMEDLAQSYGMERLRKPTLPTISSDDLRTPPPYNSVSQLDEAIGKQTNPLDTLATQDSHMNGTGRSKPDTIQYTSPRESSFTDPFGTSVNPPASPMNPAHERSDRRGPQELAPGLKQEKTTAQKEMEAIRSLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH74</accession>
    <name>A0A8K1FH74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">glutaryl-CoA dehydrogenase (ETF)</fullName>
            <ecNumber evidence="11">1.3.8.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_002541</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13389"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid metabolism; lysine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid metabolism; tryptophan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH74"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01151">
        <property type="entry name" value="GCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000003">
        <property type="entry name" value="glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000006">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000008">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="41"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="156"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="261"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW63600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="418" mass="45573" checksum="84E7C6F45AD517EB" modified="2022-08-03" version="1">MFVTRLATRHALRPQQTRAMASGGRVAFNWKDPLQLDEQLTDEELMIKKSANDYCQGKLLPRIVEANRNATFDKNIMKEMGEMGFLGPTIQGYGCAGVGYVSYGLIANAVEQVDSAYRSAMSVQSSLVMHPINTFGSDEQKEKYLPRLATGELIGCFGLTEPNHGSDPSSMETRAKLQGGKYILNGAKNWITNAPIADVFVIWAKDDEGDIRGFILEKDFPGLTTQYIHGKSTLMASATGMIFMEDVEVPKENMLPKVKGLKGPFSCLNSARYGISWGALGAAYSCYSIARQYTLDRSQFGAPLAANQLIQKKLADMSTEIALGLQGSLQVGRLLDAGQAPVELISLVKRNSCGKALDIARAARDMLGGNGLSDEYHVVRHSINLEAVNTYEGTHDIHALILGRAITDIPAFVPRMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH76</accession>
    <name>A0A8K1FH76_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004516</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH76"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="462" mass="52311" checksum="9C77FE26C2534ADB" modified="2022-08-03" version="1">MHKAPSSSHSQWQLWVVASAAAVTACTLTTAVIYLTVLRSQTSKHKSHKTSRRRRVRSSSSEEEEEETKETMPVEENKPVVYLNNADACFDYVVGKNDADEFEDVKTVAKAICPEWANADADDIAVKIVSGGITNRLFRLIWREYSVLVRLYGDNTEAFIDRSVENMLFALLSKQGFAPTYHGRFTNGRIEGWMEARPLEPYEMSMTAPINFMNLIGKELGRMHLISVPLDHAPVLWSKIDQFERLAKDIVFPNDAAKRAGLENLNLASVSEDYAWLKSILPSALNQNGKDLVAALADADEITKQAFAFANEVVFCHNDALSGNILHNDAWDRVQIIDYEYGGYNFRGFDFANHFCEHCGFEMDLNLYPGPEAQFTFFRGYMEAAAPELLASLEANKESKAFFHALYPIVNRYALASHLFWGFWAVVQAAHSKIDFDFLDYANKRFSTFRYHRTFFAAASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIN6</accession>
    <name>A0A8K1FIN6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000974</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="726"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="768"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="875"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="954"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="991"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="74"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="407"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="728"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="651"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="681"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1297" mass="140377" checksum="E9AAB5D4353B73D9" modified="2022-08-03" version="1">MATRVEDVAVEGTGDYVAVASPSHQDKNRLEVAFDKVDNVQDSESKQQLSADGKLVSMSELFQFADATDRLLMAVGTGAALLAGTSQPIQIVLFGDAINSFNPSAGAPTDPHEFRAQINKVSRNFALVGAAVVICCFLQVACWSLTASRQAKRIRSAYVSAIMNKEIGWFDVNDPMQLSTRVADSSVTIQEGMGRKVGDGLNFGSMAISGIVIALIKGWKLALILMAFIPFIAFTAFLAMKVLSRATQAGIESYGKAGAIAQESLSNIRTVHMFNSISHFVKKYEDALTLSTQAGIKKGFAVGWGTGLMFFTVFCTYACGMFFGALFVANDRRDECTHDCYNGGRVLTVFFSMIMGAMALGQAGPSVQAMFSARAAAYDVFAVINRKSLIDPLSDDGKKLDNVSGRITIENVSFAYPSRPEIKVCSNYSLTIEAGETVALVGPSGSGKSTVVSLLERFYDPLDGLVKLDGVDVRELNVRWLREQVGLVGQEPALFATSIMENIRHGCPGATDEQVIEAAKMANAYTFITEFPDGFQTEVGERGAQLSGGQKQRIAIARAIIKNPPVLLLDEATSALDTESERVVQESLDKLLAASRRTTIIVAHRLSTIRNANKIAVHSGGRIVELGTHDELMAIEGGHYRLLVEAQNRKKDDDMDEMTEMQPHRLKSESFSSSRTNSYRLIERSGSKVSVKDHDEQTENSDVTDGKAPQVSISRIWKMSLPEWKFLATGALGAIVNAAVFPVWGVLLTKITVLFFQLKPRDELLTDARYWSLGFVGLGIVFGASITLQHYGFGVTAQRLISRIRLKTFTAMLHQEVGWFDLEENSSGALVSRLATDSATLQAMTSDTLNQGLVNLTSLAIGFGIAFYYSWQMTLLLLATSPIMGFSSYIQAQMMSGTINNKKTNDADTAAGAMLSEAISSIRTVASFSMEKALNVAYVAFLDASKAADTKAGIVGGAAFGASQGMMFFNVAFLFYMGGKWVSEGTITFEGMFMVIMVIMLSMFAVGMAAQSATDQTKAKKAAARVFSVIDRKPEIDSTSGTGEQLTHINGDIEFKNVVFTYPSRPDAQIYTNYNLKIKSGQTVALVGASGSGKSTAISLLERFYDPAAGTVTLDGADLRKLRLPWLREHISLVSQEPVLFAGTIAENIAMGKPGATRDDVIEAAKKANAYDFISNFPNGFDTDVGDRGAQVSGGQKQRIAIARAILRDPEVLLLDEATSALDNESERVVQESLDRLLSLKKRTTIIVAHRLSTIRNADLIAVTKDGAIVEQGTHDQLMALSNGVYKGLVARQMGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIQ7</accession>
    <name>A0A8K1FIQ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIQ7"/>
    <dbReference type="OrthoDB" id="120613at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="187" mass="20335" checksum="0D1AFC61B617606A" modified="2022-08-03" version="1">MDIQLSSLEDLLSKKQEDRGAQESFDVMNGCRGTVYEDGQPAPEYKYDTDISVKLSVQSPDAGKMELNVVKKKAENGKTTYGSVQNLLTDGAFGAVNGDVEKKVKIPTSVTGCDKAGECALQFSWKTNSGRSFVTCSDFIIKAPTPAPTPAPTPAPSPTVTPAPKEEDDNDFRGRLRDYSRHIQARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ96</accession>
    <name>A0A8K1FJ96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ96"/>
    <dbReference type="OrthoDB" id="115781at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422465" description="Transmembrane protein 198" evidence="9">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="10">
        <location>
            <begin position="45"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="31529" checksum="66F6F3BA524BE970" modified="2022-08-03" version="1">MTLSTMWLCVLAMLLPAVNAENASDAVKTILTTAEYITVFGAILAAVAIIVGVVMLVSGYRLFRVAIFVSGFVIGGLGVASLLEYIFENKSWIETASWIGFFVGGVIVGVLAMSLYSLSIFVAGAAGGVLLAFTLQTTFAYRIYPSHPNVVLIIIAVVLGLICGFLAVKFEKPVLVIATSFFGAMAIAWGIGYYAGDFPNGADLKHYRTEESDGHWIYSIPDAWWGYLAGIVVLFALGLFIQFRKTGRDGNYHKVGRRHHATNAVPQYNNLDTPPVHAQGGNPRYGNPVSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKL5</accession>
    <name>A0A8K1FKL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ParB-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKL5"/>
    <dbReference type="OrthoDB" id="58047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16400">
        <property type="entry name" value="ParB_Srx_like_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1530.10:FF:000008">
        <property type="entry name" value="12-oxophytodienoate reductase 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1530.10">
        <property type="entry name" value="Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="ParB/Sulfiredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB-like N-terminal" evidence="2">
        <location>
            <begin position="186"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ParB-like N-terminal" evidence="2">
        <location>
            <begin position="469"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="607" mass="69006" checksum="FF0901470EC3DC7C" modified="2022-08-03" version="1">MAPNLRLADNATTENNAKTGVMENSPAQQPRRASLSGIRQPTPSQSIKEEETPVIDGESSQDEEEAQSVPRRRKRDVVRQISLRLYLKGKDIAGDVLRNVRGEGVEEEETTLSRTTRRPLWMPKTQDDSVLIRGTPMETLTARAQEKDHHDVDAFFSSRVTDPTSYFYRFHFDDYRHLTPQKAEVQLVDINWLKPHEQIVSAERVSGLKKATINWDAYTEPLLVDIKSGAILDGHHRYNVGLQLRLKQLPAVLVDYLGDDTITVDVWPECGRTKLTKEEVIKMSLSPNVFPPKTSRHRFTESLPPISIPLSVLRQNPTPINDLTLSIPMNPKKATNEAADDNETSKLNRVRDVSINLISTAQTLATTVTKSLFRNRLRKIDNTNRETTQLDMIKRPPMDSSDFFTAIRENDPTSSFCRQKAATFEDLLSSDASRRKSFYLTRIWDPTSYFYKYNFDAQPERHPKKIAVKLVSIKWLKAHEQVVSWERVDGLRRATVKWDAYLEPLLVDVVSGAILDGHHRYHVGKQLGLECVPCVLVDYLGDDTITVDVWPNCGRDSLTKQEVIDMSLSNDVFPPKTSRHTFSDDLPPISVPLARLRVAIAENYADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKN4</accession>
    <name>A0A8K1FKN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Calreticulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_010951</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 14">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKN4"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000002">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009169">
        <property type="entry name" value="Calreticulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF2">
        <property type="entry name" value="CALRETICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002356">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00805">
        <property type="entry name" value="CALRETICULIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 11 14" id="KW-0143">Chaperone</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487393" description="Calreticulin" evidence="14">
        <location>
            <begin position="20"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="206"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="359"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR002356-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR002356-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW61888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="47693" checksum="650E5BA07D51FCEB" modified="2022-08-03" version="1">MLMKSVIGLAAAAVAVANAEVYFHETFDDAAWASRWVASEWKPASEVGAFKQVAGEFFTEPSDKAIKTSEDARFYALTAKFDKELNNKDKDLYLSYLVQHEQKLDCGGAYIKLLPKDTDQSKFGGDSPYSVMFGPDICGSTRKTHAILNFARPGKDAVNMDHNTEIRAEADSEAHVYSFVIKKDNTYDVKIDGLSVKSGNLAENWPFQPAKQIPDPDQSKPADWVDDKMMADPEDKKPEGWDDIPKTIPDPEAVKPEDWDDEDDGEWEPATIDNPEYKGEWFPRLIENPDYKGEWVHPLIANPEYFEDDALYNIAKNVGAIGFELWQVKSGTLFDDILVTDDEEAFKKHEEAAVAKAKAIKEKKEEVEAAERKKAEEEAKKKEEEEAKKKAEEKEDDDEEEEKKEEAKEEEATEKDEKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKX8</accession>
    <name>A0A8K1FKX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKX8"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01122">
        <property type="entry name" value="Twinkle_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="entry name" value="Zinc finger, CHC2-type domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="T7-LIKE MITOCHONDRIAL DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873:SF0">
        <property type="entry name" value="TWINKLE MTDNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13155">
        <property type="entry name" value="Toprim_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56731">
        <property type="entry name" value="DNA primase core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="2">
        <location>
            <begin position="383"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="756"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="795" mass="87805" checksum="18D65BF27537C532" modified="2022-08-03" version="1">MSTVGNSSTFVSSYYQLDDATEILSFMDRKGLVRRETDSHWVVKECPFCHPTRGKVDNLFKLYIHKSKGVYKCHRCGAAGSWFDFKQKLQGNVSVGSVGGMLHGDGGPGASLDPREAKVISVLDNQKAMAIQRNLFDDPDFEPIRQYLIEKRGISEQVLMKYGVGAIEQPFRNENGEQVVAKCISFPWMARQGDLDTMGVLRSSSSPSSADKNQFDVIRLKIRALEDKSQQRLVPKGGSWGLFGWNTVPTSAEEIVVTEGEFDAMAVYQATGMPAVSLPNGCQSLPPNVLPLLERFKKIYLWMDNDAPGQASVEKFATKLGITRCFIVRPPADSKKPIKDANDALLAGADLKKLIHLAEIIPHDQIATFEQLRRDVYEEIVNPIRACGVQSRTLPSLNRLLKGHRLGEVTILTGPTGCGKTTLLSQLSLDLCGQGVNTLWGSFEIKNTRLIHKMLTQLAGKNLRGDVNAFEAVADKFEALPMYFLRFFGSTDVDEVLDAMEYAVYAYDVQHILLDNVQFMMAGQGRGYDKFERQDAALDKFRKFASQKNVHLTLVIHPRKEQEDVDLTLTSVFGTAKATQEADNVLILQRTRGQTKLDVRKNRFDGTLGSLPLMFDADSNCLKEYGQETMDENVASIHLEAEMQLEQKIRQQRLDRETTNVDTPSNDLHVVMATPQQEETPVSSGVVRFEYTSDEYSDEAGERVSQYSLRAMDDKPTSVGVNGSASSYHVNGVNGINGVSSDDEDRPNGMHGGSLNGSSSGSGRLNGSGPSRRGPNGTHSSGGEPFSAFTPIITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL41</accession>
    <name>A0A8K1FL41_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBX domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL41"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="84"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="190"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28481" checksum="EF5AF7564CC9939A" modified="2022-08-03" version="1">MPNIVSFSSLRDNNGNDDERAPNPNQYYAGGASQQGGGSGLSVIGPNDGQQSADFVANIIERARQQAQEEGAASAAAAAGGSGQPRHVITFYRDGFTVNDGPYRARSDPANRPFLSAIERGLVPSELEGENRSEQVEIELVDRRHEEYNAPPAPAYTAFSGAGQAIGSTSYAAEVVVSGDIPAQRPVIDDKKPTTTLQIRLHNGSRLRETLNLDHTIRDLHAIIQLNNAGGQSYTLLAGFPPQPISTHLDQTIEAAGLKGAAVTQKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL62</accession>
    <name>A0A8K1FL62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL62"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46930" checksum="FB955DC231E8F5B4" modified="2022-08-03" version="1">MELDADPATLDAIVAFLDDYQDADASAWPGIVGTESSSSLTSSDGVESAKRKRSTRKAVNSNRARERKKREFLRLQQAADELDRQLTSLLQAKADRMTRAAQESAKRSLELHRERMSAWKEMAVRQFCRRNAAEAENVRLKELVAEQRDVLCGLKRILERQLANAKFNASPHVHVGSWSSSCHGDARSMMQMVAELLAGLKSAYSSTDACLASTQSMRAAGLDDETRLVELSTSQFAIEIVNMRFFPFDPHRVAEAYWAMGLNYYYREFDIAREQAEVEGRETIFLDQISQDWATGRVNGRKHSSVQRFVEKDRVVAILAFRYNTIQVLEEELSETVCSGYHWSVFQPPEVGASDACHWVSSVRINLHIHDGLTLSPEIITVLYEYFVAKLKRDVDTMFELMEDWLLQTPGGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLF5</accession>
    <name>A0A8K1FLF5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009371</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLF5"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412">
        <property type="entry name" value="KELCH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412:SF489">
        <property type="entry name" value="RING FINGER DOMAIN AND KELCH REPEAT-CONTAINING PROTEIN DDB_G0271372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="50"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="567"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="609" mass="67850" checksum="C178BA32A0F94F63" modified="2022-08-03" version="1">MPKDTTPSAMRNSVLAMTPSVHSASCGIGEGQERSQRHQLYALLEQNVLTDVELVVQGECIAAHRVVLAAASPYFHALFTSGMKESHERRIELHELNAAAFRELVVYMYLGEIHVTGDTVLAILHTANQLEILSVVEICCRQLMLELNVSNCVDIYVSCEGLQMRQPCRILANAALAMIEAFLGDVVESDAFMQLSLPSVVRLLRHLMISGRTTACLRAWRCYDPHLRHHELKQLLPGLSSCQLERVNMSKPLKIPVLFALGGFNGPNALRSVEYLDFGTNEWFLAASMHERRSYSGIVVTGDEKIVVLAGSCSSRHLKSVEQYDPERNRWELLPSMRKARSYLGAVYLRGYIYVIGGFNGLSHLASVERFDCQTRQWEDVAPLCIGRSGLAVVASRDAIYAIGGYDGRRHLRTVEMYDPIRNEWTLLPHMMRHARNGPAAVFAPHKESILVYGGECRHGMRMDTSERLDLNTGVWEDMDHLVDCRSGHMAMSMLQDSFVFCLGGSNKKDEYVDAVHRYDPLNKQWMVHSRMLSQRCGLSVALVHVSRDADCFHSQPPSNRWKLRSDLPSPSTETLSSSPSGVESVHAFAPTPVSSSASVSTTAAAAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH0</accession>
    <name>A0A8K1FLH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007907</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH0"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="410"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="153"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="962" mass="104992" checksum="B002BD64F21830D2" modified="2022-08-03" version="1">MTQWFLLRHGLVQTSAARGSVLTLSSAPSVWSVASGRCCVASSHWMRRYSTSSVPDRRKRNHFKSNRDHKGNSSKSKPGNWNLFDSTSGSRVGGSAATNTTNATGGAQNATRGKPAPKKNRNVARRGNAAVEQKQEPVFTNKFQNLLSFAFDEEDDEDGGDKPVDSKESGKSLLRSTSLAPAKKLSGVLKLQQRKEDEEEEEESDEDDIFTSEGTNDLAISALGLDMDSTNDDSAPASLLQKQKKAKPKTDATDTTGKKKLLKKQKKKDGRSLLKNFKFENSIFGGDDDFFGHVDWDERDTENREERRFKRQQRKKDKEKPKLMLPPQEVEIPTRVTVKDLAERMCIKSKVLIKSLRDLGESGLTDDSIITNDIAEVAVESLNMIPILLPPEFVDAELTLPPDDCSSFPVRPPVISVMGHVDHGKTTLLDALRKANVAASEAGGITQSIGAFTVDLGKKFGKLGTMTFIDTPGHAAFSSMRSMGSEVTDIIVLVVAADDGVRPQTEEVIRLAQKNNVPLVVAVTKVDMHAHDQREVIDRIAGELLNLGVVVETMGGETPLVCVSGKTREGLDTLKETIALHAEVMDLRADTTVHGEGVVLEAKIARGVGAQVDTIVKWGTLKTGAIVICGQEYGKIRALVGPDGKRLKQATPGTPVRVIGLKGLPNAGEPLLTVGSEERAKEVVEGREELLQWDLLAATEEAEAEVTGEIAHFRKRRYMGAMAKSREIELRRRQAEEEAKRVASLKVGEDGYVAKVVPIIVKTDSVGVITAIDDLIATLPTEEAVIKRILGAVGPVSSSDLALAEATGATIYEFNVRHPASIDQEALQKNLSLRHHNVIYSLLDDVTELLRENLDGVEETEVIGSAEVIQEIPITKSGRRTVSIAGCRVTSGSMTMQAKYRLLRDGEVIIEDVTMESMRHFQEKVSEVTKGQECGLQFQGIDSFRPGDVLEAYTVKVVKKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLK9</accession>
    <name>A0A8K1FLK9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLK9"/>
    <dbReference type="OrthoDB" id="119845at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="706" mass="77681" checksum="AECBE9CC6E5CB444" modified="2022-08-03" version="1">MERETFVAALIAALQENEALANGVERVEETEGDAAMQPMGLFEPPRVQSSTDPTQAMARTAYEALQFDFPVVDDASLLALADIYRGIADGRVSDVALAADFALSTTMIEGVEYLNNVEPSAAKKRRGSEASGLLAAALLLCIPAFCLANPQSRVVAGLLRNLHPPVQVKTLQPLPPHAEQLMRDHAALEAAETDGEGDAWKTDGDFLEVFAAEEDPDDLSLVYEGDVPSQRLSMWPGPSSTSTQLLTASREQQLQFLASKTFSTTFSMISSEKWSSWGLNDVLFCVIRTLVTMSDENHESGVETPLCGPSGEWQRYLFVLRDHVLRLVTTSDVGIATLCKLVESFQPAKTTASDPFSFSFAKKTETSTDTASVRVVFRVLAELAVAKEFHGSTTRRAQHTLAVHLTQLYSVILAQLQSLTPDVSNADFATQHGDFLVVLLQLLHFVLDEATETSASGVVTRLHESGLLRVWLTFLPTEDDTLKTETPVWLTPLLRLLAECSLWLGELTEYLFRVLKFKALLPTIYDQLPAECALFWLATSQHRVAFPTIVTMPSGLVVWELVSSERVFPSSTASYLESMHKMSDALFLLEGLSKALASLQPALVNDLRTHLQKLYSTRFTTAFQYPGFAVPVDTEASVPHEEPEPPPTKESQLARRNDAEQEEEKEERGRAEALQFIALRNRLRQCAKTILLARTGSAAGSSSKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLZ5</accession>
    <name>A0A8K1FLZ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012959</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLZ5"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="575"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="740"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="877" mass="96944" checksum="917F52892E9D196C" modified="2022-08-03" version="1">MTMPSPLQISVAVDVDAEQQLASPHARPPPLSPSAHARARMVFETPPLRRETRLNNIQLPPYENSPGHGGGKHPVTEMTGLLGRSRSFPSSMGSYSPTVSRSPRMTREKTAKYESKWQRYAMDAVHATPCVIIAIALNLMICVPFGLSFFPAEWQDLPMPRAVGIQMFLLTTAICQFVFVAKSSFDGPIGMMMVENVPFMHTLSMSIINELGPKDPRVLPTIMVTYALSSVVVGVIFFLLGYFKVGNVVYLFPKHIIVGAIGGIGVFVLQNGIENATGHPFDWTQEGLLSLFDESVVWLWVSSAFLAALLALLTRWIRSPVFPPVFFVSIPPLFYLALLILGISPKDARAHGWFFDKAPDVEFYTMWEQFQFGSVEWSVIPKQTGTILGLTFFSLMHVPINIPSLSLTTDHEADINDELVAHGISNTLGGLCGSVQNYLCYSTSALYYKCGGGGRMSGLAVGCAMLVFFFIGPNAVAYVPRCMAGCLMIHISIDLLKEALIDTYDELDKMELATVWVIAAIMTFWGMNQGIAVGVLLACITFVMQSASLPTCAPIRGSMSASTLRSNAWRTAEALDVLDQESRSIHVVQLHGHLFFGNANKLTEYVQTLFEPKAASPHPLASNSSTTPVPISYLLLDFTLVVGLDSSAADRLTKVKYVCDVHQCRLVFAAVPSIYRRFTEHLSNIFVDQSMFYVASDLNGALEWCEDSILQSCTASRDLKTLVASSANDECAHLRSLQQLMPDQPLRIIHDMLEYFELEELDAGQVIWKQGRASDRALLLIDGQLQSIIEEEAGTTEDIAVGAIVGELCLLTGEKRKTTVVAKERSVVYTLTREKLEEMQTKDSHLAFLFQGIALRYTSHRLQYVGNRIWETKCLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMG5</accession>
    <name>A0A8K1FMG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007893</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMG5"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF75">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463712" description="PA domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="690"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="69"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="788" mass="87824" checksum="AB2F89FA4338E522" modified="2022-08-03" version="1">MKTFLGLFVWSVASTVVRADLGSSMASAVLTIKDSGLTFFGSSAEDSNWGAPLAQQQAVNGERRSFHPLVFTTDSITDRFGCTPRSNLAKANSKFSVPSTPFILIVDRGHCSFSEKAFYAQQLGAMALIVTDTPEEAYNRTRAENVTTEQRDMEFSCAHGEAEAPEGVNLEDFNKTGWSDAVNVPQCNESSTCESSICIPTGKSRQVCCLWDLPDEMGFATNDVVRSVDDITIPVVRITIRNGRALKNMLAESKDKEFLVSLWKRDPPIMDPSQFIIWLLAIVTVMIGGYKGATTERERALRKQEAALMPTMTVTASVDFSAPAQSMSPTSFLAAEQAAEQNRTAVMNTDAPESVQTRTTYQEEELDDDEGDTLDLTIYHAIAFVVFASAFLLILFYWNIVIVIVIFFAFGSISCTSHVVWQPLFNRISYLRGQPFEKYESKGWIADFAPETWTVADLVAFAWATAIAVTWFVFRHHNFAWVLQDFFGVCLCILFLRTIRLPNLKIAAFLLVLVFCYDIFMVFISPYIFKESVMVKAATGGSQAAPTVSDGYCLRYPLDTEHNCVREQMPILLRFPKVLDWREGQSMLGLGDIVLPGLLVVFCARFDYATRGQLCGRVKPHLARLKSSQNLEAGEFSHAEQHRLPTPELSSQNIIVAPRRGLFGIMMWGYALGLLLANVGVALMKKGQPALMYLVPCTLGVLCLVTWRRGILKKLWNGPDEFKSYCARLAASRTITEQQGQEGYHHEQHPRDSDPALVLMADTTTPMSTYSRTDDTPKYDAQGVTTYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNC8</accession>
    <name>A0A8K1FNC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Armadillo repeat-containing protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNC8"/>
    <dbReference type="OrthoDB" id="449062at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895:SF0">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ARM" evidence="2">
        <location>
            <begin position="302"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="54912" checksum="739259C696EA6B7B" modified="2022-08-03" version="1">MKKPSGAKKAQISQETFDEVVQENVDEFDMTLEEATLDAIAQFESQGVDLSNIIKSVGASVAASGAAEDDAGDVLGRLKKLIETLKTESQEEDVLDALQQLSTLCDEVPEMKVVAGRNDAIDPLVNLLASPANDDVTERVCTLLATLCTDNTDNQDFVGQRGVEALAQLLTSSTGKPTTTIARLLMTTRVVCTKHEANKAHFAKAHGVEAVCEYLSTATQDETLSKQLAATLRLLTINDDPKATFSQAQDTIKLLIAKDLVAYIIDTIKHNNDKPEVLSSWIIVLKQLAITEDNCKKIFELSGLELLFQTMLQHERNLTVVKRCVTVFRNVAAADELKEYIITSGGAAQILVAMQTHIADASMQQHACATLAAIALRSPENSTRLVDLGAPRQLAFAMRKHSSDTAVLRQASLAIRNMVARAPELRARILDEDVEELLREAQKYRGCGDEAYAALRDLGCDIQLSSFGTGAQPKAQFNPVHVESRKLLDSVDEAAEAPFARMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNL7</accession>
    <name>A0A8K1FNL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc transporter ZIP11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Solute carrier family 39 member 11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Zrt- and Irt-like protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003767</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNL7"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF211">
        <property type="entry name" value="ZINC TRANSPORTER ZIP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="312" mass="32857" checksum="ABCA467F24E85BC4" modified="2022-08-03" version="1">MIPDQHPVVQALLGTLVTWGLTALGSAMVFVLDVDNKQTSQKILDGMLGFAGGVMLAASYWSLLAPAIEIAEESELYGPDGRWAFVPAAVGFGLGALTLFGTEHALPYIEKFLGRPQDFSKKDDDYDATRAYNVSPVTSRGSTSDPMAHYGVSSASKTNSFRRVLLLVIAITLHNLPEGMAVGVGFGSVGQSTSASFANAVNLAIGIGLQNFPEGLAVSMPLRREGMSPFRAFMWGQLSGIVEPFGGLIGAGAVMYVQPILPYALSFAAGAMIFVVVDDLIPEATQSGNQKLATLGVIIGFIVMMSMDVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPN5</accession>
    <name>A0A8K1FPN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM RBM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPN5"/>
    <dbReference type="OrthoDB" id="442677at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12394">
        <property type="entry name" value="RRM1_RBM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12395">
        <property type="entry name" value="RRM2_RBM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034221">
        <property type="entry name" value="RBM34_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF25">
        <property type="entry name" value="RNA-BINDING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="151"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="259"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="345"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="440" mass="47584" checksum="9D33C62424F64B2E" modified="2022-08-03" version="1">MARSKKRSAATEPAAEAATAAPVTITTGASLADVFAQSAAFFGKKASYASAEDVQPKPTEKQTDAPAEPVSNKKQKKNPVDAPVAAKQTPAASDAQPKKKKDKKKKKSKQPESGDKTDTESSAAKSEETSEEAAAAESALTPANDPEKSDRTVFVGNVSLDASSKDVKQFFSSCGKVEAVRLRFLPVAGTAVNEHGNQKLMMKVCANKKIFTDKRDFCHAYVTFASKESIDAALKLNRSIFMDKAIRVDHESPKVDPQRSVFVGNLSFRVTDEAIWAFFDKQLKSDEEPAPVENVRVIRDRDTGEGKGFGYVLLKSKALAAKALSLQGKKLEQRELRVQVCGKRFKNTKGSGSKSERTRASPGAASRIAMKRKAHGDPRAEVKERKSFEGAKSKPTKPKGKVVGGKRRRENDVPATKPKKPKHAARKARQAAEAAKAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ54</accession>
    <name>A0A8K1FQ54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ54"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF43">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="12689" checksum="50AA47EB0D091720" modified="2022-08-03" version="1">MYDFCLTLPYGFLLGVGGIIGYVNSGSTTSIIAGGASGLFLTLVGYASLQEYKQSPVTSKLWPALSLLVSAPLTIVMGNRYNKTDAFFPAGFVAATSAGMSLFYVAKLIATPKPSYKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQN0</accession>
    <name>A0A8K1FQN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LMBR1-like membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQN0"/>
    <dbReference type="OrthoDB" id="73273at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652:SF0">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="58508" checksum="314CAD6CEF8C33F5" modified="2022-08-03" version="1">MSVDWFLIILVIIMTVILLIANVYILVHFQHDDDKNTAYFPKALVIFGLFFTQATVLLLPLDVANNSTAIGCAEGWNKTCGNINMDLLWLIVFGCIIVFIIVLLPYAIYYYEADDGEGNMNNHQWLEALKLEIATVVCAAIIIVVLYVTVSKSHVPMKAMTLQSTSTNHGFQEYIDGETLSTAVLDHAALITPQKITVTLEVSFPIYTTGLVSFIGWFAFTVFTGIGLIALPLDLILAFVYRPKFISADVYAHQKLCLQRRSQELLEVGRNIKASMELPGAKTRKQKKLDFVTLNKFKQSVYLLEEDMQELKLCHEDFKNYNPLYSVAKLVLGIVGSVVSCMWIFHIALYMLPPTPVLPFLNSYFIWFDQWFSLFGTISVGVFSAYLLACAVKGCFKFGMRCFCFALHPMKLHGTYMNSMLFNLGLVLACAIPAVQFCDDAFKDYGRLTSIRTMMGVQIHHLQGMSVFWEYNIFVYGILSFAILTAIFLSIRPRDNASPVDDIRKKIERQVRERNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRJ4</accession>
    <name>A0A8K1FRJ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001218</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRJ4"/>
    <dbReference type="OrthoDB" id="167134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="48680" checksum="0DD0772DAEA7BE3E" modified="2022-08-03" version="1">MTVTLFCTVVGVGSVFPVDIDISRTVGHLKKKIKEEDPDLFSFGAARLKLYLAREGDTWLNSRDEDIKALKKGEIPDRIKSLMQEELLLDETWDLNDDAYFGNNLERVKGDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLESESPQDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNRLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKVEIFVKVLDKQCKDRVFSRLKEGSDQTDDPLVMKTFVHVESPETFCFCLRWKHEDNDARWRSFLSMVPAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS63</accession>
    <name>A0A8K1FS63_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS63"/>
    <dbReference type="OrthoDB" id="69430at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="102" mass="11747" checksum="23E8536BFF963B0D" modified="2022-08-03" version="1">MTDEASRCMYPSKPCSNPRAVKVGGELHKLCEQHRRKANLNQQRSQYRKRLRELEEMQQRMDEDFADAQRLIEETDALVGAMGPDDNLTDEDLAILIALLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTS0</accession>
    <name>A0A8K1FTS0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTS0"/>
    <dbReference type="OrthoDB" id="74661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="430" mass="48160" checksum="BAE7B9F862A50563" modified="2022-08-03" version="1">MDEVEVELECAVYGEGSVFPVKIARDAKVSALQEAIAGVVSTEQHAVPPRLVTLYLARKNDTWLKDDRHVKNFLQAGKSAEYEEMRPSWILGEDYLGANFQPGRKEIHVLVELPEAAAGEKSETAQMMKEIHEHVVRPKRKRYVHSEMSSTKGNALLQDLNIRVKPADSVPFTTEDPTPVEAFTWESVCNEHGQLIVLTEEQQRERYRTYVEDNIGDVLAEKKLCVLGVEKGKNILTATVPGHDIDLVGRTDMLVLSDVAKREPDHLEWLPEVKMLIEVKRNVKGGSMFQALSELIALDVLVDDPVMALLTDLTGRWQFFWVSEKSNNRVIIRTVIISNPSAAFAVIRTLLAQSPNGDADITLPYFEGPVKRRKLAQLLPSIGEGGESSGIREAIERYYDIASVLGPDIDMARSVAHQIVRTIPTFSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3G7</accession>
    <name>A0A8K1C3G7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3G7"/>
    <dbReference type="OrthoDB" id="7318948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42511" checksum="341C1CA73EDB9B01" modified="2022-08-03" version="1">MSMEPETESGIAASHEHTDALTTGPSLLHRLRKKAYKFSSYAREDHGKAIYAIAFCDLLPLYEKHFAAAGGNRVTIYECLENGGLDVVQVYVDGDAEEQYFTLAWTIDVLTGSPLLAVAGFRGHIKILNVITQSVVTVLSGHGNSVNELKFHPVDPSLLLSAGKDESIRLWNSLTGVCVAIFAGHLGHRDEVLSADIHLTGSCFVSSGMDNTIKIWDLEDSAVQTAIEKSYKEPRPADRPFDTKFIQFPAYCTSKVHADYVDCVRFVGDLVLSKSTGNKVIFWKPNPSRGKDAVTVLREYHYKDAELWFLKFGLDSRLEVMAVGNKKGVISVFDLDSDAERALCKLKHSNCKSTIRQVSFSRDGHSIVCCADDFTIWRFDLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3I9</accession>
    <name>A0A8K1C3I9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3I9"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF13">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="444"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="636"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="649"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="820"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="833" mass="94806" checksum="97ACC3E8DA440AD9" modified="2022-08-03" version="1">MHRNPRFNTGRVIPNAMPPAGESTGDTASMPSTAASETQPTPPAEGETVPKKSPARKNASVRFGLRREATFRSINSLLLMSSGQANINVLRTSLDEIHERVRYHWVLHPQSIRKTLWDVISAFVVVYYSWMIPFMLGFDWYVMPSSTRIFFRVLDVWGFLDIALRFRTGIIEYGAIVMNPTRIRKAYMHSLWFPIDILSTIPFEYFFTDPTNVSTRKTIKMIKYIKLPRLLRIGRLWKYVKKYKRYSSTIITLNALLFISHVAGCIWVALLQPCSGNSLDSEPRCKAGEEMRIYWIAFHHGLVSLLGISVNHIESPYQLLSGGYHRVPDDPISPTLYIWSSFVSILGAVLTASLFGTIISLVQSWNRAENAFRKKMDQITHEMDALSLPKHIRARVTAYHDYLWLNSRTFSNELNLLKDSGMSLALREQIAVYLFKDYLQKIPFFQLATDNVLGMICMQLHQVIYMPEDYIIREGEIGKELFMIVKGIVRVMPPKNCFDKNESKKILLGEGDFFGEIGVVMEVERTRSVKAECMSELCILARSGFEKILVEFPEFATAMKRLIIKRVSEMWQDDGRERIEKMTKLADYQMKKTVASYHRLNKLRGTAHAIQTFYPRLSKKVKELVPPDVLGIDTATLPEARVSPSPELESIEEQDQEEASAEDHLQRSSEVGLRARQSPPEPRYNIRPVPYENDRPAGIPEGDEDAPSAPNTPRTSAPNNTYVSNTRRSSVPVDDGEALKRIKKVKKQLVALDDKLETRMVEMERNIARILQTLTPTRSREDDYTQQLDGDMLSDVSPMKARYGALPPILRHVDADVPGGSTNETTGAAQGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C435</accession>
    <name>A0A8K1C435_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C435"/>
    <dbReference type="OrthoDB" id="10052321at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="356" mass="40082" checksum="700F3363C89E62BA" modified="2022-08-03" version="1">MLARSSVARCVAAVAKTSRHGMAVSVKKATMPAVVARMQSQNAQVRLCSSSRFLSLADEEDGEKKRRRGGEDGEDDGEDNGEEGLEAAEGEAAAEEGEKDGDLELEDEMYKFCVAETDDLDSEIMELYMSDPLKWTPERLARKYHLSKQRVEATIHFQAEEAGLSPEGFVAKVEDAKTLAVQRQKDGAAKLASAEARGDEQEVKRLQKRDRQQQRDVDEVDDEVLTAEETAAALGLDDERYRNPDFFFLNDEFEGYPPLTRRLGKHKSTDKLYPQEAIEIQRLATNNKIEELKSFAKPTDVKNRWKIAVKDTSKNKLPLLVRTEDRSLRLATKEEVLPRSWVRRPAFFAGLSPSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4D6</accession>
    <name>A0A8K1C4D6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4D6"/>
    <dbReference type="OrthoDB" id="108900at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455363" evidence="2">
        <location>
            <begin position="18"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="29219" checksum="8755601B65BE4C35" modified="2022-08-03" version="1">MSLRSLAIVSCVAATLATPFVDAHARVYEPAPEYTISDRNKNWSPQAFLEKQGFKTSNDFVGYLKQNGYETLRDFMDKPGVYKPEKGATFECGWSNPNATAKAIPNSKMRLSGYTHDGPCEVWLDDVRVLHGDQCNKEFTGQEMKIDYSSCKQKGCMMKWYWLGIRPFKPVSWQIYKECIPLKGTGEAASDNDSVPTTKPTTKAPVPTSQAPAPTTKAPAPTTKAPTPTTKSPTPTTNAPVPTTTDPDTTAAPDATKTPSCNRRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C558</accession>
    <name>A0A8K1C558_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C558"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="230"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="44631" checksum="B78B3358E7006EBA" modified="2022-08-03" version="1">MEKTLVFVKYAYAGDLTNLLATIKTDKVDPNVQDRFGMTALHWASYGGKLDCVQELLKAGASVTIVDQNGRNALHHACRKDHDGVVRFLLDDGKMDINAVSESKDTPLHKAVTGQSIKCIEILLQLGADPHLRNDQNRTPLEELDADTSAVKDEMPEPVQTARLGEEIATWRRQSLTESKSSTGRTESLTMLRFVGRRGSTEASAAKYTSSGRAVAAETTLVTSFRNRLSEFSSRGSSATDLTSHRSSNGAWASPASPKGLPTQSETDTPESIGRKNGANSSTATVFPLNLQSLNAPEHAPVDATASYTASQQSIPSLQSQRVESQDLPQRRAVQKKLKSAGKRVIMMLRVKKNMTGEDKRQLIRILLEKRMKAPSKADQSNPNDTSNDRKPLVRFTSGVQISLPPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5D5</accession>
    <name>A0A8K1C5D5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006613</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5D5"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045148">
        <property type="entry name" value="TCRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377">
        <property type="entry name" value="TRANSCRIPTION ELONGATION REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377:SF3">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="5">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="51172" checksum="DAAC0563AB65FC17" modified="2022-08-03" version="1">MTAMTTDKAPMNAKKDDQEQYLLNAISVVGPWSVHDDDDGRLFYYNHETNESQWTAPDGFHGLEGEFMMKLMLQEAIARSGVWSAHDAGNGTLYYFNEKTRESVWERPADWGVETEADQKELPPPPPPLPPKKQREERTLEGKAPAKAKKEKKSKTKKHEEQPVEAPREPTPEELALQQRREEDRKRYSEQFCDMLRDKKIMPFCKWSVAFPQIATDPRFLAVPTMDERREIFEDFVHHRRTDLKSEKKQKLKDAKKRFTKFLRDHFAAQRLNGAFDPKLTLSLFLATWEDIIDPGQLKAVKEEALAFLPLAVQEKLWDKEMSAFLESTKVEREEEDRLRAYLMDKLSDRQYISWDDLVIQDNVRAFYSTQGATATLSEALQRVVVNQSRKTRRTHRETTTICVLVTFSISIALEFKTSLISIPFSLLISIAIAIIVTFPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5P7</accession>
    <name>A0A8K1C5P7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5P7"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="816"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1198" mass="135147" checksum="819AE247935CABDB" modified="2022-08-03" version="1">MTTYYKTRDEGTGGFYVSISMMKQHASSSVEELRWRSAQEGHAALLRRVSALLAKPWYSVVSTASHDKPQWWRLFQEDECKLIEWIEDFVVHVTLETLREAVGRHLLRLYPVASRVSKRRAEEGGKTQLSDLLDEWTCDFAGVDPYDRVTQACLREVFETNALSWPENWGRDECACSNLQPLVDENARRCLCLIDSSAPVEDLNLEVFLNIIRADMEKVRSRVQDVWKLSIKPDVVEDIVPGPVDHFFLTDSCFLGSKELSLLESSLGSSSHLLDIAIADDASVSILGECDESLEALRSILPEIMTLMERSLLSASKAKQMPPRAVFKGNTHQVVLRMQSSGEFSAAPAWVQATYDKHRHGPVVATALVVLNADQQSPPVVQLRPEGDTTDRVQFFENPSVACCPRGGVQAQVTGYCGRVMTFPQQLPYRIVEASDTHGLTKLLTVQVVEPVEMSDVDDLDEYVVSWNSVWSAEEQRLAHKWLHQGENLSRPQSALHWKITPTKTWPLSFRKLELDRPNPLSSLETAFQSWLGRIIDKPRWWESVYGSSDELNELVSTFRTQYTRLKVKDARDKCLGELKSLVSACAKQYHVTHIPIACWREVRRRFPHLAWFEALCESDPTSTLYYPCHYEPTTVIDTVAPVVTGISLPFMNAYASYSVEELRFQRLPKVSDIRNQGIVDPYTNLVWLVAHTKLLAVVARSEDLPEHLEALEKFNFLPSIPTLTWDAFENDVESAYLPDEVMKLLMVECDEISELSVPKIESALVRAAGGSVPDGVLDEMLAQALAIQHDFTTIRTRVNSLVCTMANKSEKDTFTQDETLERVVADGLVPNDVNEAIQRHCDVLSTRFSADCDAEEQEARLLVDPCMYSTDKSSTKHLPVFTVPRASTTAEMRLCFDRLIGKEGDIIHSTIRQWIPADVRIRLNGSVEFLSYINNLHPHRDQQMYLLVARVFAAMVPLLERVATQLTGPSPKPVFLRSNPTIYHTTTREFDEPARFIRSFSLRGRVVQAVVALHEVRVDGSNCLGDVEVWHRDDGSYNGLLATGLYVVETTGFDTTPSWSFQRPIYGSNGSKLLKVTEEIPSITCHSGRMVVLPNYYRQRMLINPPSSQLGRVRVLAIYLLDPTQPKVSSAEIPPQQREWIYDAVVLPVAHHGNLPSDLHNTLKEMIGDVGWSHEDAVSKRGSARGCYLRPKTHTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Q6</accession>
    <name>A0A8K1C5Q6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Q6"/>
    <dbReference type="OrthoDB" id="124329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006:SF2">
        <property type="entry name" value="ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006">
        <property type="entry name" value="THIAMINE-BINDING PERIPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13343">
        <property type="entry name" value="SBP_bac_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035435874" evidence="2">
        <location>
            <begin position="21"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="40869" checksum="2CB50D73F75CFF32" modified="2022-08-03" version="1">MKLLRILAPLGAILFASASAQLHEEAHWHEEETKTLDELHADAVKEGGKLVIYHGGDFAEQQDLTVDAFRKAYPDINLTMVIDYSKYHDVRIDNQLATDSLVPDIVALQTLQDFTRWTKEDKFLKYKPAGFSKINGPFKEPNGAWMSHVCFSFSFFYDEALLNGTAPPQTPADLVDPKYANLIASVYPHDDDASLFVFARYLEKYGWDWVKKFAAQNVEFVRGSHVPGELVAQKRKAIGLAGSEPSGIPTAKVIRGNGTDFLTWAQRIAILKKAKRPAAAKFYLNWLLSKDVQTNLYGSWGGSTRVDVKPESGKALWEIEGASVPEFPKFMEDRAKIEQLKSTFALYFGEVRGEPTPGQLGLHPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6F5</accession>
    <name>A0A8K1C6F5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6F5"/>
    <dbReference type="OrthoDB" id="79466at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020266">
        <property type="entry name" value="Tom6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17112">
        <property type="entry name" value="Tom6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36721" checksum="EF76435D8498564C" modified="2022-08-03" version="1">MKPASRLAQPPDLLAQQHRNPQDHQDNAPFAIPVSYPRANAPPRSTTTATTTTPFYFDPRPLAYRGRYSEPWAGRSVLYKFVRSTGKLALFHLMNAFLGYTAFCVCLAGLAGSIGLLPLCCFGVVIFRVLLFAVYGFAQLDVMLYNSIAPVDQHVYVQVPQNPRTAALSGRRLSPTLTTFSPISMAALAYFLTVKFALGVLSTICFWAAITAPISLISSALGSGDNTFLQISFGPDDIAEFKANPVLFVLLSLSLFVIGVAFMHLVARASQKATRFFCCERFSTYRYIHQQYDASVPYYPVAINAYGSVAHDAPSHRQHYSDSSYSNTSHNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6H9</accession>
    <name>A0A8K1C6H9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADPH-dependent FMN and FAD-containing oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003265</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6H9"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000015">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000032">
        <property type="entry name" value="NADPH-dependent diflavin oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF10">
        <property type="entry name" value="NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="10">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="217"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="67890" checksum="2263520931EF83BC" modified="2022-08-03" version="1">MEVPRVLVLYGSETGTAQDVAEHIQQLAWNRHLLDAQSCALDEFPVAQLLPKCSIVIFVVATTGDGDAPDNMRMAWRALLRKNLPTNWLKDVQVAVFGLGDSSYAKYNAVARRLQARLVQLGATEIVERGLGDDQHALGFFGALNPWLERLWTAVLQRYPLPAGFVVNDSPKAIEPKYKLTLEAAGSDAVRLASEFDPRSDKSTFYAPPSTAIHKDTGLRMAKVVENRRLTAADWSQDVRHLVLDLGTTPVAYSAGAIAVVYPENTTGINELLEYVDLPGDTVVSITAADGLDQDDFPSPTSLKDLFSKYLDIQGTPRRTFFARLSLFATNEEEKEKLEEIASPEGADLLYDYCIREKKTYVEVLLDFPSVKVPLDLLVQFIPRLKPRSYSISSSTLQHPGQVHLTVAIVDFLTPYKRRRCGVCSAYFQSLDPTKEDHFLPIWIKTGLFSVPDPTESMLLIGPGTGLAAMRAIAQERHVLKQQASGTDLGSTSLYFGSRHQAKDFLYGDELTAMVANGALSELHTAFSRDQSHKIYVQTRLAEQKERIFELLMNGTYVYIAGSAKRMPSDIYEVLRDILRSVGKMSLQDAEKIMKTLVRTKRYVVESWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C771</accession>
    <name>A0A8K1C771_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EML-like first beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014318</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1935234at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF3">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25828">
        <property type="entry name" value="CC_Cfap43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like first beta-propeller" evidence="11">
        <location>
            <begin position="170"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="347"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="566"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="672"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1212"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1407"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1454"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1485"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1655"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1735"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1834"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1934"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="677"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1407"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1433"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1458"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1487"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1670"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1685"/>
            <end position="1719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2035" mass="227400" checksum="488B924659F6E639" modified="2022-08-03" version="1">MSESMEGVETHEEEEAVQEPEIQSTPENPEDADEETEGFVVPAPMDDDEDDDDDDEEDEEVPVEVPSAPLPPGEDPLLLESSAYDVFDLARPLQRCEIARDHVVFGSMCSLDAGKRHILHLLEPPVESVHGGVVLVAAGNTIQILKLGTSLGTNNIVDRKYLFGTSGSGIGSLAVHPSRRFFAVAEKGVKPNICIYQYPSARVCRILRNGTELAYSSVTFSQDGETLASVGCAPDFLLTVWNWRQEQTILRSKAFGQDVFSVRFAPQDSGFLTTSGVGHIRFWKMASTFTGLKLQGDIGKFGKSELSDIEAFCVLPDKKVLSGTERGVLLLWDGNFIKCELLTSRRHLPHNGRIHVVQYDAESSLIVTAGSDGFVKFWSFEAIDRADLPPDDTVALVPMKRQILIHPKMDIRAVVKLSTARYLVQDACGSIHLLALDENDDTAFEVLTDYVPNATGRTTGVVASPYEHLAASCGIDGTIHAWDYTTDRCLFSATTTVFSKDSDGSPRASSAAATAISWVPNASAFVTTENQLVPKSRQVIVGFSDGVVRVFLMDLIKRAWVRTNVFKPHRARVSTLAFSPSGVYFVSASDDDATFFLFKVVPSGKTSKFTKFPPDYLPLGFQRVGESGVRAVSWREDDEALLVTLTNGRVIEYSIPMDGTLEALAELKQRHAAATEMETESREDDDQAKENETYELKLTSREFPALTRRRPMATPELDALEALNPNGNPQVEDKIRSDFHVETRVAPVMAWTAQYQTKDTFFLSLQGGNALPSASNALLLCQWGSLTPLLEYATEDTTPLTTLVTSSSRKYMLCGLGNGKFQLRSLPRPYAFLTGEFHDVASDSNVLSTRVVMSFDDSYVLTAGGDGNLSICRVHSEQLELAARLLMEKYETLQVEGKIAGEQAQQKQQAQCDMLQKAALDAKNSEDGGGSTLTAPGNELTMLPKYQRARAYAAYIETHVDEVAKDEESFRGVVRLLTDTNSTLGMSLAGMPRVEEGQSTALLALLETLDLANPSEAYTIEDAKRQSEVDAKARATQSKQDRTRDVLFKMRAQLLELQAQDASYPPESRLDDDEWEIDLDYGEILAQQGEQACEEVRRELAFAVEKEELLLMKMRETYVNQLAVELITLRAFESGLCVQSFRTMKMPPVLQKRLNEIYTSEAGVSKGETSASSTISRRPSVLQIMTKDSALDETFPLKEDERMMILTANSKAQGAHPPGAPMQTDGSHASGPVHGFEARKRLRAERKDRLQQWMTHKPGEDADDPRDLVAIAFAQRNMGDYKLKTESNYVVPEDQRVNAAKKRRQMALLEERIYEARLTFNAKVLELRELKLLLVHEMKQDAERLEALGVALQREDHEASLAMDDEKTAAKTTPVDVDLSEWPEQRERASDADIELYLREKKVLSVSTASQQQQHQMASSLTHRRRSSVHQPVKIDGKRVDAVDPSITAVSRRLMHQQSDSGGQDTSSLSTSSSFRVRHMPIDPSAIITSSPQANSSSGRKPTGDSDARAIRIYQIKQEIHRLQRKQRDEIRAFDDAVAHLRREKMRLDVVFKQCELRLFTLWHELSLLEQFESRENLLSSKLDKSKSEKALIVAEIRDIQENMSHKKKDVEEWGKQERAIQTEFLTLVNGANGTTPHPQFLALQKIFKKKIKRAKKKNQGGKDGKDGTGGDGNGGSGGNGEGDPAQDDDDDNDDDEEEEDSDYDDDDDDNDDDDEEDVCPLGCDLQLYEKVLALREKRADVDDALSDLAKALEELKKSNERQVAKQRQIDKELHATEQDIQLFQSEKQTRFNQLDVVVALSKQQIRSLVPKATSQPSNASSRWELPESASNCLVFTSRSFEALSERIESLQRENKSLRQQFKDLHKQQNLLAKEKKVQQETIAQIQHKCEQLQMLKFGQLVDIELLDKACDTTRVSELQAKVRAKEMDTERELSRVKQTQQQLKLRILQATEQNTALLSRIAALNERQFALEKELNQANVGQSVLNDDAELLEQELRERNKLVKIVKLQAREVEALKQEIGLLRGKDGKVYAPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T4</accession>
    <name>A0A8K1C7T4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="24103" checksum="7494B9A114CA0891" modified="2022-08-03" version="1">MATRQFHALEKSEAENARLKALVAEQHAQIQSLKRLVMKKQSKLLSSYRVDYPLWPYQMTNDPFTSPVMDMTMEQDLLGMLRGIDRIVADSRYPVDPRESLNVANLVATDSSEHPTIEVLISRPFPFEHKAVAGALWDIWSMQPATPIFVIASTSQTSACDVLRTLALMPSVKGSHFEPSSSAVVLLKGTEPPWRHQYSSSCWTRTGRPGMGSPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8C8</accession>
    <name>A0A8K1C8C8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8C8"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="766" mass="88663" checksum="E443102F0E8DD8C0" modified="2022-08-03" version="1">MTTSILLLAGDEWFLRELVSFLSHEDAVCLTLLAIECKWTSLTHALLYKPLPTRAISTQKLADYTAERGWWHLLALVREQDVRLCLGNKRVSLDVQESAFARCQRIQRSFPRPFPAKVMYAAVRRGSLDEVKWLHTCTKIQYGCFYWYEHNTSERESIYHCAIKAHHLDVLEWLLDLHERTAGGLKVMLRLKDSALEVVCWRKGQYLHAAISDEHLVQHVDITKHWYSSPIELCPLMDWAAMRGDLSLLEKLHSDPILTTTCTYRAMCHGANAGHLDVVCWLHEHRSEHVNHISEVLTMATSGEQVAVLDWLHVHFDLQEFVAKIYRKTAQPRRFKAMIWFLRNFKNIMRHAEPPPVYELTGAPLELFQLLFDMYDLSVDAQSVKVAVRSGNFELVRWLVEKDAQAVVGNDADRFKLLTFAIDGGNIDLVRWCIEELDTWFNGCALQATTKKHVLMAKYLWEKLRERNEVIHNEDQMLLTAVQRGSLELVQWCVEDLGAWDPSVLQQAVSCGNYAIFKYFVAKSEERGESDTTMHLKQNGVDARCIVRMLCDDRVEDEMIDWILTNCPDTGYQVRALDVERLKRKPWHTLRKMLHYHPSLCYHIRNLPLRAVQEGSLNDFKRLEAIKYPRLFTKKTLNAILDNSRDEILMCWFLTRSGISLVKDQRITKWAAKYGVVQLLDLLRDAARGMSDEGLFIKFLGTVVWEAIRCDQVSTLRWVERQELSQQARARLWTSKLTKLATGCAHLASLAWLRDCGLLNVDNKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C960</accession>
    <name>A0A8K1C960_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C960"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="50145" checksum="B108F0D7F9913EEB" modified="2022-08-03" version="1">MKFPLPRNPYPSFQLSPAYIQQLEVLTNALLDQGVEEYEEFVHLRNRKVDAKKWKHLKTRENLSVYRAFGDHSDDKHLNKLELLMDATSGCDMPTSRLNIKGNNRLLGVGSIVGTLPDLLYCASTNSEDEMQVRTAYCDDECVDWQVLYKLRDGSADNPFRNHGIKWYVKSSPSLTKYVVRPRDVILLDCMGEMSLPSGERVGYILYHSLDIPGCEPMDGFVRALLSTLYIFRSTENNSIEVYMRSMCEMGGNVNDSIVALSVANALIGVWKMPWGGLNKKLTGMLMQQRKQGKKPAKLAKSSHCGLCKKGYSILRTATECELCRHQVCSSCVTVRMICHVRSADGDLHRLLCELHNPSVAVGRDRNYSPSMVRIETEDDWQRQYQLVSKPSSVESSLVSQSLSSSMDSHKLHLVAQMSQLRLAAEQTYQITKENERVMNSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9M4</accession>
    <name>A0A8K1C9M4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9M4"/>
    <dbReference type="OrthoDB" id="165487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="279"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="662"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="748"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="878"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="935"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1089" mass="122529" checksum="6F865BB434DA57FA" modified="2022-08-03" version="1">MLEFPLPESFFPQIALNADEVKYYKRLGKERLDQLMRIAEDADYAYKWTDLKTKYGTSVQKTQFLDFRPANKATYASVLVKSSVLIRDTRPEEILQAIAKTKTKEYRKSMAYLHGNSFADGRTLFKFPSAVANKRPDYSYRAIKWCAYRGKGRDEAKSLDFAFLEYAGKKSPTPGSMVVGFCLQESIQRERQLPVLEGYGIVRGFMSRTGVIISRTHHANAYRVTSICQIDGDIEPVVRSFLEEVLQESVGAIVRLQGLLDRQRVSSMKFLEQWEWVANSDRKVCAVCTKGFFFHRKHHCRACGEVVCSSCAPLRELDEPVYDITQLRICQSCMVLAGSKVVESNNLINETVTSSENANSHDTGKVTPKNNPMDDRRFQEMENNDRAHRPSDAARMLLQDGTPQATPRRRRLSSMSNFIKDPQGATQTLVHLVDQIRDARDTINITISDGGESHSPFGEEDAYSELYDQANRLRQTVEGDHDADGHELDDDASDLFGSVMDLTFQAARATRFAGEKVLSSRASDFDDFEEVEDVLNSPSSNPDDFSGSTDPYAPSNYNRLMKYGAQQERAAAARAAEQARLAPPLPPRRPPVRPKPRQDARQDPKVRLLEKKIMDLERELRDAHRKLSFFEVDEPEPEYNHLPVLHEDPYFDADDFLRQTQLQQEPRDGGKPRPKSDGTLKPNLPPPIGIDFDENHPRDIASAPRPPLPPTSGRGGGRANTIGRAPSTADMVSELHGVMNSIEMVKPRRASASTMSPPPQPGSNRSSLSRSRPPPPPLPMSAKRMYIDENGQLVEEVQTPKASPKTSGLEKTASSTASYQHFLNTSFDPSVDDSVLDSERYHELMAHNDVDPEDQMDLSFSEASGSHHNFFGQHDANPAFFGNESMPSNRPPPRGADVPPARPSPVLRRGPYDETDELRALADGLTRPRSISAPFRSNSQLGGSPTQERGQRPVWSDGASVRREAAQTQVLPRHPEDAVVEIRACLASLHRECPSQWEHHRKLVSVFKILKSLHRDGARSRFRSLNYEDIRYEKALQETPSVIKLLKLAGYISLPQKLTMRNVDPQYLALFLTEIDFEINEMQASQDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9S7</accession>
    <name>A0A8K1C9S7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9S7"/>
    <dbReference type="OrthoDB" id="416441at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="3">
        <location>
            <begin position="427"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="736" mass="81997" checksum="C945EA4C6393E260" modified="2022-08-03" version="1">MAGDAAPAAAAAPAKTSNAGAYMKSAFFSMISVTIATSAAKFLSGQEDYIVCSANVNDNSWLPSRYFSVRYFNPQETHHESQYVAMSDGVELAVDTYLANYLWEKQQPVPTIVYYTRHGRGYTVDFPFNLFNSYTSPRTTAYTDRFIAGGYAWVAVDVRGTGASGGSKKHDFSDEEVQDGYELIEWITKQPWSNGKVGAVGHGFEGTGALLLAASGHPALKAVSLNGAAADVFNSAFFPSGVKNIKALKDFGSFTYDLDRQIRWREIPTFKGRLMMKHFGGNVYPVNKDTAKLNQLVADHFKNPNITEELEDVHFRDDVLKTVGVPVSQLDATRFLAKIAASGVAVHSFGGYYDMAVARSSILLHQYLTNTLDADTASLLPELPEGAVREPGHHRLTLGPWSHAGVDNTDPFAQSKQKCFWHLDEISRFMDHHIYEKRRKITDLEEEEPIHYFTMVHNRWKTTDTWPPAHLGEQTFFLGLNKTLEEVNAPEGEETLEVSPVSQFDAVTRWDMVNHMFGNRPFYYHDRAPMASEFVTFLTPEIPLTEITGEVELRLFFSVDKPAVNLVAYLEDSDYMPPFKNENKRPGVTYITEALLNPVHKTIRPDSSVHSFLKKDSREIVPGVVYEAVLKFQPVSYVVKHKHQLRLSIGVATSKDFAPAGPEQATKLTVHFGGDYPSSLKIPSFAGLNFDSVVPKEGAPAGLESEPVKPVEEVSEEDEFAEETEEVAKPTEKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9X3</accession>
    <name>A0A8K1C9X3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9X3"/>
    <dbReference type="OrthoDB" id="77835at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702:SF1">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035435658" description="PA domain-containing protein" evidence="3">
        <location>
            <begin position="30"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="75"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="191" mass="21404" checksum="C642AD6F887675BF" modified="2022-08-03" version="1">MQRTYRRLRSYALLAVLLWLCVATRRAFAVASYVQIVLAEGHGVMFCPECDDPLREGSYVPALSTFFNPSGYFVIGELVYGVPNRGDLELMNIDEARGRVVLFDRGKAPFARKVRHAQQAGAIGVVVIDDLSERRIETEVPSAFLQDDRPTAWQGVEIPSVMISATDGERLRSFMALVQMEIMGEMHYLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBI1</accession>
    <name>A0A8K1CBI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBI1"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF6">
        <property type="entry name" value="THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48222" checksum="088F4E0A1A7021C9" modified="2022-08-03" version="1">MARASASQGDGYGYAVAMLISGTFSTVIMKTEYGIRAEGVELCADPANPGATTTNCPFDKPWFGVLQMKLAMALCLVFLYLRKVVKHTDYLETPLLRLRKHGNKYLNTPEATAVRNKQRGRQTSQESTSLLRGDDATQSHVSLKTMAAVALPSLLDLLQTVFANVGLLWISSSVYQMARGSVIIFSAIFSVKLMNKRLYAYHYASILVVAISVVLVGWAGTKSSSTSSTGSDSNAIWGLTFIVMAQLLTALQIVVEEHMMIALNVSPMLLVGLEGLWGLVFYIVLVPVLTLTPPATTAFSKIWHEDFYDSIVKLSNSPPLIALIVCYIIAVGTLNVTGNYVTKHLSAVMRSIAETLRTLGVWMLGLFVFYVVQWRGPNSPGEEWTTSSWIELLGFVLMVYGTLSYKKLIQIPISGLYAAERREHAAATYKSPFMSGMHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBL0</accession>
    <name>A0A8K1CBL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBL0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="80" mass="9208" checksum="5B1878FC46633F5C" modified="2022-08-03" version="1">MRGVVMRHRTWVVVERTSDDFTPLKTFHIGTPQVYDATQGHQSIVCDLANFLLLALDKHLDREQRELETQALMGSRVTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBU0</accession>
    <name>A0A8K1CBU0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBU0"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016071">
        <property type="term" value="P:mRNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028322">
        <property type="entry name" value="PNRC-like_rgn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15365">
        <property type="entry name" value="PNRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="537" mass="58660" checksum="64395F8033EA008A" modified="2022-08-03" version="1">MSSRDLIGRPLVPFFDADENVNTDLEVDPTTQSHENLDVDARVWDKELGYFVYPSEEPKPTLSAQRPSIGSTPIAIRRNSGANGSPSTVANGGSSKLLLTPDMLSKSAPDTSAMPRVEATPISDNHNGRSTPRSSSAKRASRQRGTPSKSKNKATKNDSQSSGEDKPNTTNTAVRENKNGSSTPSKKNKNKQKTKEKEKEELSANGKWAWSAFQSSPDPKSLPLPPFVAGGSPGFGASPPPLDPPKIYERLDPPGVTEPAGQPRPPSVPPEVSAMSVEHSMTQDLRRMLNIGGDLVDGIRHGQGAIVFTNGDRYEGGFQQGFRHGHGIFMSERGTRVYDGEWRRSERSGTGKERWATTGDRYEGEYLKDRFHGKGVLVTGSSGSRYEGEFMNGRRHGYGRMEFGQQSASRGLGDKTDTVGAVLSMGMSKRSNATNSTIATRSAVYEGQWRDGRMHGEGKYTRIDGGFYEGTWVDGLAHGIGKEVSMVTGEVYEGNWKKGQRHGEGSVIRNGKRRKGLWENGQRIKWTTAEMPVVIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC37</accession>
    <name>A0A8K1CC37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC37"/>
    <dbReference type="OrthoDB" id="441724at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431470" evidence="1">
        <location>
            <begin position="21"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="501" mass="55952" checksum="D6F7EDCB386B6011" modified="2022-08-03" version="1">MGRWTRWTCGVAALLGVSTGVPDLPTTLKMKYSNPVLPVMIEGHEKNLILTTDIDGIVLCTDRPDDSSFASDMGFDYSRKLLRYQLQGLVHGFVVAHLEIPSLKYSTQMPIMFFDLQQQWLSPAALRAVFDASNAHGFIGVGYAYRVPFSPLWSRLLMSTTRYRYNAEATWQEKNNKTAHMAKVAHEGDNTTEWDWSEPCASVDQIEDDASNNQGLTFPIQHASFSCQSDESSANATETRRVDMFGEYTSNWDVVIDFNAPCLMLPEEFYDSLAGWTGLEFNDELRLSEIDDISQLPTLSFSLGHDGPVHQLPLQDLILQNYSGTSTSSDSSAWVCIERSTSIIHAGSSLFSAVEGDVTATQRYRLQGSMSLRVSNMYYSPIVFGQMVLFSLGDMLVDGTNKQVAFRKPVNLTSTRALPICSQQTDCVGAQVYSSSRNACQDPDCSRYYFQSLDEETRQCVVDPDWLVFLTTTVAVFAAAEWGLAFKMKSLLQRQVQQSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC56</accession>
    <name>A0A8K1CC56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC56"/>
    <dbReference type="OrthoDB" id="427777at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039589">
        <property type="entry name" value="TBCC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052:SF0">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="435" mass="49084" checksum="08C747273C4E746B" modified="2022-08-03" version="1">MPRIWLRLELFEHGLLQFPSKYSSSLTLANVKQSLDALHVRLQEDQQRIVASEGDVDMEDTAPASAVYTESDNIRVVSFPVWKETVAPIFQWREQDYKAFWLLLVQFHRQIPVKDVYVVDSAVLFDETQCLVHQTIPLFKLAIFLFIQTVKPHSWKNKYSIETFNATWYREDFAALGQAGTAPTNPLAINGNMSPQFKGNMSPPPPQSPHTVGMQDRSTSDAYYLEFIREKLEDLFSLLYPSAELNEESTTGISAEQLDLLGFLLCAGGRSMLDYSQRVSTVYPKWVPSGESPFSENYKGDAATRMENAVKLSRFFKKHLYLNETLYPPVGFSLNALQSGSYSPVVTPSTGPAFSLADAQEPADDESNVLQRPTVLSNLSKTTVVKRAEEFADQDGNSDLVIFSCHDAYIYILGPVRYPFQRLNCLTPFVCSFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCF3</accession>
    <name>A0A8K1CCF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_000607</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCF3"/>
    <dbReference type="OrthoDB" id="197980at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="784"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="917"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="959"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="987"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1015"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="342"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="375"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="834"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW60565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1099" mass="126348" checksum="56AA26DBC2735E35" modified="2022-08-03" version="1">MTHGLTEPEFASLTTNSSSAPAKRALPPIETHHKADKDPRYDRDALLAAYRNSHRHRKEIQKAQEKLVIIENVRKRPPKLLLRETTPKTAHSHQHNDHHSHSSKKRDAGTHQRGHYFHGFAARFLPPQFLNRDLETERTDDWAAVRISRAMRRYRMVRELAASRLPQYLGVQCKKVFDECCKCTPLAQGPLTSEDGVYQIAGPNLPKILGMLRSRKNVGMDLLQPHGISQHTVTHVAAQRGYTELVRELLTHWMQHHPMESPYQPYSLALLTRLLHHVRQLRAMKTLVSESNSELRDIIAQIGVVSFSHVSDALDKLHEQDVTLADLIRICGHPLVLCKDAAGNTPLHYAAEGGYLSLCQLLIQHGAHINAQNQAGETPLHFAISSMHEDVCTYLVQRKADVSICRYVSLTLLNNVTIRGTLVEAPEGTAVCKVMPILHARSNAITALLTEHRVPKRSIWLSPWRRKGWRRRRRQPGDPKKTTATVTPASVVSSRASEGTTSEFIAPTEAGIRTSPTSTQAKTPNTPLPLTGNLAEDGMFTRVDSLASSSLFKDCHARDILYFRTAPGNSLMKAHVLCVLMLGEHVAASEAIKARSKQYKGKLFHLLIKNLPQVAVVAMDSFRTPLFRCSLLKDVRERNQRWILDNALKTRREKREALLVLMKGQQKAGKHRRKKQRSLSLAWITHKLYHVWEVLMRVRHFVSVQNVFATADADREFKNNIICEPKGILYEYVYDHAELRGGLSPTLALIIKTECKELLDHPWFSQIMDHKWNAFARQTFRREFHIYTLYFVSVFIATYLHVGDPYLGMPVGGYRSNSFTAHASWIEYFRDAARLVYSLINAHYTYEEFRSYREQGSIKAYLRDGWNWFDLVQITCVWMLFVTEIRGMFGAETFSSEDFELVAFRESYYRVKTWRRYHLRTTLMCIVGPQIFIKWIQFARGNRTLGPFVRMIFKMFHDIFVFLLVFCVFLLGFGFAFFILQLDGCRTYFSAIAMVLQISLGAWDWDAIEEGGPIAIMLFILYAIIGTIMLLNLLIAMLGNTYDKIWEDRLLFFELERAKATLSIQMAMDDDEYDERYWCQRLYVLEGDRPIEGIQFQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCI2</accession>
    <name>A0A8K1CCI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type E3 ubiquitin transferase BRCA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_000170</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCI2"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031099">
        <property type="entry name" value="BRCA1-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763:SF0">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="21"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="16">
        <location>
            <begin position="581"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="16">
        <location>
            <begin position="687"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="295"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW60128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="793" mass="88472" checksum="88381A36D638D64B" modified="2022-08-03" version="1">MELLTAEQREAVRLVREELCCILCGNVFEDPQCLDCKHNFCRECIYEHLRKRESFCPKCRLPTCPSEVTRNQFLQSILVAWKTVELDLKKFQNPEEQEEELEDKAPIPMTHSVSNGYANGSMELPMTLSSRGPVANSKWNIDTAGLKQEEEARQRREQAAALFSPSQRIAAKNAALNTQNGQSAATTPGGTVTATATTTESPAPARTTTAASQVFSPAGASPVSMMGSVMGTQELNGYMNRIQAQNSFLTKWTAQNQVNAQRKEQLRQAAASPRTRAKPTISAVERVQEIMNAATTGSTVGKRKRRIFGSDDEDDSEGDESQTQMPSTIMDSPDLLGRLKGTTLRRKPATPRRVITQLNVESDETDDQEMKGDDDDDDEEKEKEPVGWMGRRRSPAPKPTSRLAAQSPPRVKQTPQKKSPALKTRVLVPSSQPVDYIDMTLDDDDDDNNEDEDDEDVVEESQLPDLTVQHLRQNKRVSQDFAGAIRAFQSNSSNRLHRLSGMLEEKSAPRKPSEAPIGRGIAMRCTSALPSRAPVVTTSKPPLASTSDTSRATSAISPGDFVFVGTDLARDESKMVLIACQNLGARFGREFDLKRDNHTGALTTSVTHLITKAANEDLSHGLRCKRTAKFMRALAEGTYVVDFSWIQASLAAGRWVPEEPYEMSGDIYCDAMGKPRESRLRRARTGQRNDIFQIFRFILLCPPEEFGFQVESLRSIVTHFGASVIMVEDFARMSEERRTSNGKTPIGIVSKELPPEEARAVWNRYRIPIVRVNWIFDSISYLEVLPFDDYYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM6</accession>
    <name>A0A8K1CCM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="192163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="328"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="428"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="559"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1817"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1936"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2152"/>
            <end position="2186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2431" mass="285084" checksum="026016ED6CEF6751" modified="2022-08-03" version="1">MGAKGKSRKKKDEQKELEEEAMAEWLARGFNLQDFTTEKMMAVWMEEDGADEDEDGEEALSAKQELIRSMNVLGPVIEQAKETVARVKETVKEEAIHAVQTAWQYAEIPYFKRRRLLREHVVHVHEMDRESQKYSIIRQRVNDDWESAQEAEKELQFGLIKRNQRKAPLLHRMREMKEEADQEQHARIMADIEQKRRERKDKELAKKHRLRVEREEFAEKQRVHRRQMNMRFWKKQYTEAKEYAEQHSLAVDQSRQDAFDAQVASMKQEIAEMNGEQAEDERKDLDRAVMSSSLGLYGTALAPGEWNSAIDGDDREGTDENTVGLFSARGYQAENELLRIELMEADSKVMMLREKLEQLDQVKTNLLADKRTLMDRKDMVLVEIKQINQENEELNRLLAGPPRRDPNEEDRMQFHLLMTRRGAQTKQLQELNTRQANVQKRMELAERSEKALIVMLEAAESRAGELQEQVQRIDAKQTDLPVVIGRSIQHNNGVLTNMNGTDCEATQMTASVVNPTQLYTQVTMASKLEILKEAAQPVKEHFKKVKNISIEDWKTRELRTLEQQELEVTKNRLANLRDQLINHRNDSLRADLMQAIIRFHQGPLKLRACIFPVKGRFEWWQYHDPKRSFGLTHVEERGLIYLEPSVRSGQIRGCIRLPKSCFFRIALRIVAAQVAENGEVIVPATEDDQDEIAAQTSEILTFYVGSDYDSLQEHIFRDISGKALTTGYLAFEFFGARLCFCFEFKHRMGNHPDKAAYRLVVVSDAQYEERLQDFREEETRMRLVQKEKHVVSQLVKTLRMQTKKTSSERCAGLLQELIEVEKSKAKMWDSTLLHGHQQRFLRLEYARMLRLEIKRELAHQIDEDVLRRRGRLPTVLEQSVDSTRDTSESTGAQVEKENRKDASRLEFLARKYALVEPQYLKEKESLGEYCSFKTIESGAHKRSSGDSISYRKEALIMGLRFEWREGRTKLHVMHKLCGPTTSASRSDTSESSPAVKSEWCPLEKVNAVFLQSACAKALQERRQEMSKERTLVEKREEQVSQLQRETQATLQLEREAEKREKWEDTQLHKQKTGDLARREKLFYADAIRTTTYNQQVSSQMEFLAQRKKSVVEQHSSTAAAQNYSLRDALNEVKEEYAKQFVDGRLALVRKTWERKEKRLSDKRAQERKERAFRIQHEKELVEEINASNEKELQSLQAEQLQRAKEQLNIPNFQLVARGAFRCEHRELKAWGSKYGSGQRCKQCGKEMAESFDEVDHERGADPQLDRDIAQDRGMVTGGPVLRLRHGDHFKQVEAERVRVEKEAREQEHSEALLYDRMDPKVIEAFNFRHGMQRQLVETDGSDPLYQRVIHEAHRADFQDEILFHGRLRNYHFRIHQINGQHAETTTMLAVQRDFLASAQEENETVLAILPLVERDHGRAVALVEEDRVAHQALEESRQTLKKTQRERERAYYALEGVEEEAEFAESHAPALIESSGEMTQIVERMRDQDALTSEQLEKARSRFADSIQARDTTENMLSRLLLRTTGTAVRTRFGFAKVLYYRQEDDTVVVSPSRWEATIFIPVEELILLETMHREGEISMMESEESSMRSVLSKERTREKAEQVLMAQEDEEIRVIVAWRTKKEPEEVLVRDTICNQELAAQFEYEVTTRKELWKAATAEAKRLHQFSRVSFKRRRQVPGASHPRPNKLDVLRVTRANEKRLAMEAMEQALLQRDKALRKTFVHEHDQIFQRNFGDDVFSRALTEIIAELCREAVEAERYEAKELHQAHSHALMVSPMMPSSMIPTRVSIGYDHLWLMKKKQCELTFLAWSKELKKLDALRLELARREEIRRLEEEERQRLERRRKEMLAEERHCREFYMAEMAQCIRERKAMASAEMEMREYLRQLELEAMKAKYAKMIEERNKANDKAARRLEIKLGKNEKHRLHREWAQIKVEDALAMQIREEERAREQAEALERQFDQYLIQQSMEGKIAAEREASRLAERIREAQRIAEERRAAFEAKLVQERMMITVETYYQVAKVELEWMIAAECVAYWERQVEPLRSNLKQMEVELKRILSEKDHVVADAQAKREHAEKCKQRAHTADLELREALQTEEEYAKTYKKIHMLNATMDSAVLHGRPQLFRTIYIRDQLHKRYFYLLTESIICRSIVECSEREAARLEERLRSLETERAFKIREINVLKRKRRRAFHMRLRRSELGKIMFGGTQRRLLKLRFQQWVQIWSQRVTVRASFEVKHGLLMQQHRIREEQTQQAQQEVTTKLSILHTHQKRRLHCRLCKQEYTEEQNNRYACSYHPGAYELACIRSCPTRQLAQDVFQTTSVSEACMMHRARRWLCCDVTDEGRYGNNGCATRFHLAVRENPALKQLAEKKETAENGLLSQFQQQLQELKERNVVGKAKAATKAVVKKIEEELSGKRAIAAKYHTLDQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCN5</accession>
    <name>A0A8K1CCN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCN5"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="551" mass="60981" checksum="BC83585D72D36CE7" modified="2022-08-03" version="1">MRDSEPSSGRLSLSTLNQLDDPDRQVRIWLLSAADVKGTTFYRIAGRFQTSLQTWQVDRRYSEFLMLRDTLVKYFSRATDTCPGCLNYLHAIKSFSFPKKHMFVSKSRLVINYRIKALRSFMNLLASWSFSNSPKCPTCGGFAFEIVRNFVVEGAEPVGESNMSYIRDSFVVSTFTNADRRSSLSGTPLSLRGSFTPGSNVFLSQRQESARNRRLSHDRNTVGGGTTDANAVAYETFNDYLGQQPRLSKTSSGRSTINTPNHQDPVSDNGSGSSGSSSSSQDRKYGKVRSGSYNAYASLYPEPTKPKRAARAFSMSAVAVVPSSIPEKHTVRIDRTENDSYISLAASNTSVEPEEYMVMVPDNSVASSRQGPHQKQGYYDSFVDSYVSDSFADESLRFDGMPSDVVDKSDDELDVTGVDLGVKGKRPKASSADGLWQPWELAKYLGLHWGSDQLLCRLPTHTNSQTKIYCAAPPHTRATGEEIATRLLGTARASTVPALCIGPAAYYRSRRRFSHERVGAGSRVLDPFSVRFESQDPLSALNTSRNILCHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ5</accession>
    <name>A0A8K1CCQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-isomer specific 2-hydroxyacid dehydrogenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000100">
        <property type="protein sequence ID" value="TMW60969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ5"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="2">
        <location>
            <begin position="59"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="148" mass="16475" checksum="F2E9D1DC91AF9211" modified="2022-08-03" version="1">MYAKRIDVEGSLFKFLCRTQAPPLPPNQPANHEDRLLLHTQLRHRVDEQHGKAEGVLPEHQFEYFTTRLNAQTATLAEGCEAVVIFVNDTADAAALRKLHAGGTRLLLLRCAGFDMVDLEVAKELDMPVLRVPAYSPYAAAQNTPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCS5</accession>
    <name>A0A8K1CCS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homoserine dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_000593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15763"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCS5"/>
    <dbReference type="OrthoDB" id="67851at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000006">
        <property type="entry name" value="Bifunctional aspartokinase/homoserine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_Aspkin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070:SF3">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Aspartate/homoserine dehydrogenase NAD-binding" evidence="12">
        <location>
            <begin position="10"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="11">
        <location>
            <begin position="171"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW60551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="40018" checksum="C0C7690E35505021" modified="2022-08-03" version="1">MKRIGVIAAGAGAVGAQFLRVLEERFCTKELTVCVVAIGDSRGFVCNVDKGLAWSDVHAVLQHKSDGQTIPSWKPSDLNEIDTLDTLVAVVDYITSRPRGFDDYIVIDCTSSNQIASALVHASTNDFAVVMANKLPLSGSMEQYRQLAWSSDGTVRSQRVRYEATVGAGLPVVDTVKHVVASRDTIQTIQGSLSGTMAFIFSKMTSGSSFSEALLGSHRAGITEADPRDDLSGVDVARKMIIVAREMGFSVEIDSHVDIEPLLPPAMFELPIESFFDKLSKFDGGFAQRMQAAKAADSTLAYLGSISPDGRVRVGLEVVPLTSVFAQTTTTENAVVLHTEWFPEPLVLRGTGAGIHSTAAALASDVGAIVAGHND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDY2</accession>
    <name>A0A8K1CDY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010722</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDY2"/>
    <dbReference type="OrthoDB" id="79871at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047335">
        <property type="entry name" value="RUFY1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45956">
        <property type="entry name" value="RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45956:SF6">
        <property type="entry name" value="RUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="157"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="352" mass="40796" checksum="8C9AA8F4C83CFFFC" modified="2022-08-03" version="1">MRLFWQKKKETTATIETTSHGVNDADQEWQRLERERQKEQKRAEKERKKAAKRAMKEMKKHAKAARKERKRLERETKRQARTVQRIQKADEKRRNRLVRKRKKEEKRRRKQQAKEEKALRRRAQQQQQQQPEVEVSPAQQRPGAVPSAALPLAPPTFKERENCSSCHTRFGRLPGRRRHHCRNCGDSFCHKCLSNVKRAIPWFKLDKPQKVCYTCDVTVFNGMGGASRPGSGQVPPVTSNPSPVAAPVAPPQPPSPQLVSPQSDLPRPPSSGRLRISLRPRSRRENGSSKSKKGSLWTFPLRPLLKRKESAEQLRKRAWDLDLHLEKAELLARQRTARMLVLDEQPQFARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEP7</accession>
    <name>A0A8K1CEP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEP7"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425060" description="Glucanase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="38294" checksum="5A1012C660901EC5" modified="2022-08-03" version="1">MRFTAGILSAILAISMVKAEMPICGAWKGASYEAAKTQYPELKDAIDVVQQYGSVPWYTDNQGVADQQKVIDTLKGCDPNTKIPIVVYGIPNKDCEANYSNKGINKSEQDYQAFIVRLTAAFPSQNMIYIVEPDAMGLLADSKCAQDNMYGDRVRYAINELSKNPSAELYLDVGYWTLANDAQRKKIVDAVNAVWTPGSKLKGIALNTSNYQKTEKILELCDKFATESGRSDAKCIVDTSRNHKGPTSANEWCNANNAGIGQPPTMQTGNARAAYYLWVKPPGESDGTCTEQKSGESMIGPDAGHFFKEHFDLLWKNSYFVEKGETKPKPQTTGIGFDMLGQNATTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CER3</accession>
    <name>A0A8K1CER3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CER3"/>
    <dbReference type="OrthoDB" id="91590at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="160" mass="18069" checksum="B993E8B2E8626038" modified="2022-08-03" version="1">MQVGTFVWQKWRDAWFMATVVAQNDEDQVQVHVHGEHETTDRWVAVSSATLVRLRVIETDVTAIGVFPHVGDTVELLVMDEPLASAWETAEEPSRLLTGVVMRVYPARDASLVDVEYPPHDVADLPPRRRVCVGHGYIRLRTHPDDLHPSELLAHTRSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEZ2</accession>
    <name>A0A8K1CEZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12 13">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="2 12 13">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_012771</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:23732"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="13">Steroid biosynthesis; cholesterol biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="2 12 13"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEZ2"/>
    <dbReference type="OrthoDB" id="10253702at2759"/>
    <dbReference type="UniPathway" id="UPA00063"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000080">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000005">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053859">
        <property type="entry name" value="MVD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977:SF3">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22700">
        <property type="entry name" value="MVD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="13" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="3 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Diphosphomevalonate decarboxylase-like N-terminal" evidence="16">
        <location>
            <begin position="11"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Mvd1 C-terminal" evidence="15">
        <location>
            <begin position="191"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW61580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="47325" checksum="BFD0BA859E469DD3" modified="2022-08-03" version="1">MTALRVATCSAPTNIATIKYWGKDSTALNTPLNSSVSVTLHQDDLRTKTTIAASPAFATTHLWLNGKEQSINARVQAVLREMKALAHKQHGEQALHSWHLRIVSENSFPTAAGLASSAAGYACLVATLAELYKVKDESPGQLSSIARQGSGSACRSLDGGFVRWQKGVNADGSDSLAVRVADEHHWPALRAIICVVNDREKDTSSTSGMKTSKETSTLLQHRVASVVDGRLEQIEAAYQARDFATFGELTMRDSNQFHAVCLDTYPPIFYMNEVSRKIIHIVHRFNTFHGAVRAAYTFDAGPNAVIFLEDKDVAAVLALLQTYFPTTRDGGSLPIQTVSSASELHQWRNASFPADLRAMTQVSPSPGGIKSLYVTRVGGGTRVLATNESLVDLTTGKPRIPRVEKTKEEPAPSPSRGPLAVLTALVGMFTLLSVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF32</accession>
    <name>A0A8K1CF32_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010927</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF32"/>
    <dbReference type="OrthoDB" id="164313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="543" mass="60482" checksum="7BFEEFF70C7BEF87" modified="2022-08-03" version="1">MLSTKDTRVTGHSIAVTDNDDDVVFMAQPATAHPDRPSSLTLQGRFVAGEAFFNYAAFGSLREGLPAVNLATQLYGGLAVHAMLAGVNVSLFQYAFRPLLVAFLLEFDADQIQAGESLVQWMGTLSVFIGLTSDCYPFFGYRRKSYMLLGWIFACVMYTTIAILHATGNRDGYTYLVVTTLASLGFQVAWITSLALTIELAQREHLYERGHLQAFFFVLHFGSALLAQVGIMTTVFPADDGVSMLPTTKMHMGECATALAIVCILPLPFISRYLSEPPANCSSRLTLTIRLRELWHLLQQKVVYCIFFFLVGSLFLLGASSPSVTQAIMFWSGIMPSKMQYINFFTVLPKLAAVLIWKSVLVNWNWRRMWLLGLTIFIVGQLALLPCVYFSAVRHEWYFYVMILIAQLPQGWMDLLVVIMPTEIADIGREGVMIGLVNSFIVLITIASGSLWTSLNEAVDMNVSLEDILEDSAETRHQIFVAALIYGAINALGVFTAWFLPAQKLDAQQMRAFGGYNRMARNAILFVFAALLIYDLVENLAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF66</accession>
    <name>A0A8K1CF66_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF66"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1155" mass="129524" checksum="E4A452C36EBDBC32" modified="2022-08-03" version="1">MWLRVVATTASPPFKLISFRRATAAAITAIEEMPSPVGQAKMSAAPAQLTKPAGMAGESTLRGVLLPSLPAMTRQARTQELVFLFSAVEQIQARGILGCADKIFKIHDATLDFQTNMSLTGSSCLRKWLELLVLTGNEERCRHEAWTSSSLVVTLSLVAAWCSFDVEFNRTVHQFVRVGSKQVLNRDALHAVFEELVSWVWVKLDEYLRCLNWSLPALLQKLIVIFPATSIGSHESAFHSYPAQVREGVVDQNVRLDRHPGSFEQPNNTKNSSFSGIWTMGLQDVHLRRLEPSYDGSAGVQPLTLTTLLAFQRQLATISTSFSPSNQHFSLVSLLFAEKGTQLRLDMRDRWFRRFPAVPVKSCPTPCQQPRDRTNLPRGAKILRCFPHCCPDHLPRGFCGSSLTIRVEFTVPQADYVIPAGLFVFGRFHLSHSAEFRVGDRFKLSDITASLQYEDSPRHSWVAANELPSASMNTWLFELSPSARWFYNWDSGVAKKRRLQAHALSVAALTPILRCFPHCCPGHMDRSFCGSPLRVRVDGQANALSTETELLVLARFRLAQSQDLNVGDCIATSDISASLQSDSNPNGEWIAADEQIDCAQNCMANTHPIPSNSFRQACSRFFLLNPTARWFYTWESGVAKAHRLQQHTLSVVVVAPVRLSSQSRSSGAKWLRIVAVLSSPPFKLISFRRATQAAISAIEEMSGPGSSSTKSTKVSEACGRPRKSAATLLECDSSCDSTPRVASLPSMTAIARPARVQGLALIFTAVGRLQVRDILGWLDELFRIYDSTLAGRLNQTKPPPCSLRQWLEPLVLPHKDDRYRYNHQTPSPLVTTLSSVAAWVCFDVEFNRIVNQFVLAGAKYILDRDVLHVVFEELVSWVWDKLDRYLRRLNWSMAALVHELMTKSPPNAVSNDIEVGYHRFLVQVRECVVDQNQNGRVRHVEPGLHIEQHLSTSFSGTWSMRLEEMQLRRLDHANEDTPAVPSLALTTLLTLRRQLGTINTTYDSTKSQFSITSLPFAQDATQMQLRLDTRDRWFRHFPAGESTLAVGIHGYSFGDYVGSHTPQRGEYECECELHWNLYAWPEDDENHVALCFHVHVTASRDGASLGVVVQVIQGDIDADTRRLVTFSTLSLREKLCLVPHWTLTLHASWIHSRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFJ4</accession>
    <name>A0A8K1CFJ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFJ4"/>
    <dbReference type="OrthoDB" id="93140at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="720" mass="81320" checksum="824C5B6C9098E5FF" modified="2022-08-03" version="1">MPMDDAAFAALLEPWWREFPSQSLKIAVKSEPSDFYERYYALNLTLTDRVELWRRQYDAVEILLLASLVKPPKFKEMMWKMCGSMGGRSSECFDPESVMPCRFDVTVIPKGDRSRWYSGALEELFSFPTERSERFEETRAALVAQRSEKGLALDQVAIPVSVLLYFQDEQSIIQAIDHLVDLQRQRLKDTTHFYPFALEQVSVTVTRSPVSMELAEAINRFKATPGLQLGNLWHCGFQWDPVAPTIGARRKAVWRWATTATAVPNHRTIVPQDVVHPPGDQLSRSDTVKCHDPCPEHFLAVCSSLMYASHVNKLVIGLDSSLDSSSSGLKWCWLFYALFNSASCHSVAELRIEASEIRMDDIVRVRNLIRSPRPLEMLVNPVYEENTMSKRLDSSPTQPSQVVLQDGAMIYLDNARSEEPLTLSSGQQTFNVIHALDDGYEIMVPGYGQCWVDHQGVATEIPPSEENATNQWRLTTHSIAKLSIRVDCTGLEDQEGGIRVLLKLIGTPLLHLSICVPYDLLHHSYFDLAWTYCPSLISLSFLRTNVDSFDDVMEAYATGRCRVSELAMEECRVRDPASTFDFVHALADPSTTLAKTLRQLRVSFMNESEEVVIEDELLETLYSMLATNEQLRFLATTVSSDQFDRFNSRFDVFRGQPIRYLVSLSAKCAFLSVVKHAQLAEDGKNSATQAIGLVDSLVLSKIFFYASEPASRTVVLHTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG22</accession>
    <name>A0A8K1CG22_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG22"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422993" evidence="2">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="71" mass="7805" checksum="02695B3DF0F121A1" modified="2022-08-03" version="1">MRFYVLLAACAVLVSATTVTAMQPGRSYTMKDIQKRGQRVKDNERAKVKPANSTFAEPTILEGNDVFSGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG44</accession>
    <name>A0A8K1CG44_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG44"/>
    <dbReference type="OrthoDB" id="76387at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.395.10:FF:000001">
        <property type="entry name" value="Sentrin-specific protease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-SPECIFIC PROTEASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="243"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="452" mass="52913" checksum="30EA4554FEA4519D" modified="2022-08-03" version="1">MEIQAAADAWHFQQRRRDAEIHSQNLVRDLPSTLIKPLFSSSQGGRREPQTREEFFGLLQKVAGDQYGAGAASTELVSLEKEDPLKAIQKQHTDLFRRLRQTLAHTIDRPRSGKIDKRLHADAYAKRFNRKTRAIEPFGIKKNHKLKNMDEIEEIERKLRDYRIARTSAEVDDAFYSRVAKREANLLLEEVLQDELWNLVEETYDEVEAASGKRELPEELQQIVHDALYEGLHQDVLIQKYNVDITRRHLQCLLPQQWLNDEVINFWFQMLMDRDAELVKSGVLEKPSHFFSSFFYTKVSEGGYNFINVRRWTRKIDLFSMDKIFVPVNVSNTHWCLAVIFMTEKRIQYFDSMAGPGTKCLEVLLKYLHDEMQHKKQQPFDSEGWELVETVPGTPQQENGWDCGVFTCLFADYLSQNLDLSFSQNDMEFQRNRMILRIVQGSVPEEEDDLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG76</accession>
    <name>A0A8K1CG76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG76"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="115" mass="13341" checksum="160A103600363CDC" modified="2022-08-03" version="1">MADDGQDMALAFKEAVRFFRRQERIYDDAVEALSQWKQQHRNFTGREPGYLQLERMQDKAMKDLKDTASIMNAARKAAKVWKSIVFMDKFWTPLTSLQALLGLSTPSKRKQVKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG98</accession>
    <name>A0A8K1CG98_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Poli38472_005283</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="287671at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000011">
        <property type="entry name" value="Hybrid signal transduction histidine kinase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000077">
        <property type="entry name" value="Hybrid signal transduction histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000375">
        <property type="entry name" value="Hybrid signal transduction histidine kinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001294">
        <property type="entry name" value="Phytochrome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01033">
        <property type="entry name" value="PHYTOCHROME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="118"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="193"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="239"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="312"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="358"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="432"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="478"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="552"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="598"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="672"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="718"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="792"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="838"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="912"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="20">
        <location>
            <begin position="958"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="21">
        <location>
            <begin position="1032"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="18">
        <location>
            <begin position="1088"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="19">
        <location>
            <begin position="1341"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="22">
        <location>
            <begin position="1688"/>
            <end position="1786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1631"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="16">
        <location>
            <position position="1392"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="15">
        <location>
            <position position="1727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="TMW62665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1817" mass="202337" checksum="104DB1275AEFBE07" modified="2022-08-03" version="1">MLAHAPVPAVALALNGDVLFWNDVMAEATRIPAQDIVQQSLRSVLDCSDSDVTSQIVQAASTAQDTTTWTHECRLVFRAFKPGFHAVMDFSLTIHQDHNGKPWGMAGIAKDMTGVLFLDTQRKRVLNAANAPGFELSVDLKVVILNRKALELIEYPMEEIKGVDFVSHLVAEDCREQVTAVMKRAVEDGQETPSYTFAVMTKTGRRVEMIMNATPRYNMYGDTIGIYGVGQDITERLVLEREYNHLIDTANAPMFALDKDLRIIMWNREAAAISEYTTEDAIGASIRIFSSNKYRDKLDEVLHKAMKGEQTANFELPWITKSGRKLDIVLNTAPRYDQCGHIVGVIGIGQDITDRRAQEHEYARLIDTANAPIFGVDIEGRVNIWNRKAALITEYSLFDVLGSNLVEEFIPADYQKKVGEVLSKATQGAETANFEFPIITPTGRRIEILLNATTRYDEKGDIIGVVGIGQDITVRIAQEQEYSRLIDTANAPIFGVDMGGLVNIWNKKAVEITQFTTEDVMGRDLVQEFISEEYRFAVGLVLSQALNGVQTANFNFPLITQSGRRVEILLNATPRYNELGEIVGVVGIGQDITDRIAQEQEYARLIDTANAPIFGVDEKGHVNIWNKKAADITQFTPSEVMGEHLVEKFITQDYKEAVGSVLSKALSGTEMANFEFPLITKSGRRVEILLNATPRYNEHGEVIGMVGIGQDITERIAQEQEYARLIEKANAPIFGVDRNGCVNIWNQKTADITQYTRAEVMGEKLVEKFISEEGRDVVATVLAKALKGNETSNFEAPFLTKMDRNVNFLLNATARFDQHGQIVGVVGIGQDLTDRIAQQEEYARLIDTANAPIFGVDRNLCVNIWNKKAAQITQYSTSEVMGENLVETFISPEYRPIVADVLSKALNGVQTANFEFPLITRPGTRIEILLNATPRMNVQGDIVGVVGIGQDITDRIAQEHEYFRLIDTANAPIFGVDTFGCINEWNQKIEEITGHHKSTVLGISLVDAFITEESRPLVRKLINQALIGIDVGEMELPMTTKSGRAILLLVNASSKKDMHGNIRGVIGVGQDYTAKKHMEAAKVTFLASFSHELRTPLNGVLGMLELLREQKLDQVTQRYVHMAFVSGSLLLNLINDILDLSKIEAGHLEISKDPFLMQDLLDYVIEIFNFKAREKGLTLALECSENVPKIVIGDVARLRQVLLNLLSNAMKFTTDGSITIKCSAVPSPKLPKSQVKLLFQVIDTGIGMDNEDTSRLFSLFTKLERTRKNNPTGSGLGLAICKQLVELMNGEIDVDSELGEGSEFFFTVVVERGDENAVIDPIPAETVANGSAIDVVPTQARILVVEDNEFNWEVVKCFFAEDNHLLQWEQNGRDAYMAYKEHHDLYDLVLMDCEMPIMNGYTATRSIRQFEKEHNLPRIPIIGLTAYAMSGDRKKCLDAGMDEFIVKPISKGGLRAAIRQWMCVRYLNQKTVCRELSALTEEIEHTDVNLVPAATHNEALDLIRAISDLELEDPMMIRRESGIPTSATEGIVPMPALRATKSAYSLTGTLSVSVGDQSDSESVNELSHERLNEFFTDSPHLKTVEESPPSLTSILPDELEDIEEKSSLSLTSGDIKEALSQSRRRFSIPDFEEEDSLVSDNQKHEEADAGAFASSPASFMSSMLPEEVVIPDGDPVNYTLGVDQCGGNENLFFSLLEKYASVIEEYMRRIEGAFISHDYVVLRREAHSLKGSSAYVAAMRMSKAAFRLQLASERVMERDIPTLEEATSLLNAYELLRKENRLVVGYLRRNFSFRRNSGNAHPELSRRGDEPNACVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH09</accession>
    <name>A0A8K1CH09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH09"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36294" checksum="9260F0DFA0006D73" modified="2022-08-03" version="1">MQNGVSYTSVQDGENGGLAASNEPVLATNGSVARTHRVHMHPAKSKLLHALGLGGLLGCVLMLVTMKMVITPLERLDEPDQSVYTQFDHLYDQLELLRNESIKSSQQMQLLLHQLQQTHAAASTRTALVEQAAKQSYRELAKEYLRESRLTIREGMVLQASQKRQIEAVQRERGRVSASELLDMLTTFTAPVYQSLERTQNMTLSDRIVALRSAVLQQNLPVSGREAVLLLSSPLFDTELTKRQRFAEAQKHKPYAFFVFCVVFGFVGTWLWFAVADEFARARSVLRNMQRVVKNFVNTFVVVEHVESSSMKGYETSRYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH48</accession>
    <name>A0A8K1CH48_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH48"/>
    <dbReference type="SMR" id="A0A8K1CH48"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="136" mass="15402" checksum="848CFD2EACA3A6CB" modified="2022-08-03" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPTAGGVKKPHRYRPGTVALREIRKYQKSTDLLIRKLPFQRLVREIAQDYKTDLRFQSTAILALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHC5</accession>
    <name>A0A8K1CHC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHC5"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF525">
        <property type="entry name" value="MAP KINASE PHOSPHATASE WITH LEUCINE-RICH REPEATS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="231"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="295"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="409" mass="46565" checksum="D8FCEEAE19F0A02C" modified="2022-08-03" version="1">MPAAWDRLADEEELDASTVDELSHKDEELHDDDTTSSSTNSQRSGQRHSFQKPLRLRLLKRARVPRPSVPSISPTSLYNRLQTASVVVVDCRSAEDFDKSHLYNALHCAPLRRRGAAKPKHKKKKTVEDVLAAYAPESDVVRKLANRDMMEIVVIGSNRTSSPLLYRMDWGYRFARKLLTEGRVYSVVFLSSGFADFTSKYPFLLRGTQYPDAPVRSADPQRKLSDAPPQYPNEIINDFLFLGNFWQANDERTVRDLRITHVVNVGAITENRNKFDHIKYLDVDIKDNVDVNIGDLFAPTVAFIQRALREHGRVLIHCVQGISRSSTIVIWYVMIHTRCSLSAAYSYVLKRRPLIFPNRGFMTQLMENEKALYGSESVLPEDVDLLQNGLLAPLDRKGSNLRLSFVNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHT7</accession>
    <name>A0A8K1CHT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHT7"/>
    <dbReference type="OrthoDB" id="74460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053002">
        <property type="entry name" value="Metalloproteinase_M10B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021917">
        <property type="entry name" value="Unchr_Zn-peptidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054:SF2">
        <property type="entry name" value="MIP04191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054">
        <property type="entry name" value="ZINC METALLOPROTEINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12044">
        <property type="entry name" value="Metallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="398"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="555"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="984" mass="108974" checksum="74FF967EE922AAC7" modified="2022-08-03" version="1">MMATTDAILVHNVTEYEVLPHPLVVLDGVVNAMPSLMLSPEEWFIEARLDASRFCYFPVTATGRFKALVLLPAPGKYEVTLRMGMHCSRVLNIEYRPPVSRYVVKFYYQKSADGHSHGFDAPPGTDNSDRAAMDKIRFNALLLQTATAEMFRNAGLPRKTFAVEFATDGLPMVHLLQTTFTNEHARSIHDQELIKLVEKDIKAGGFDNHHELEFKHAVILGCSTFNPSTQKPEGHTALGGGKVGIFGSCGLHTWPRHLGEVSACCLNNSRIDKSHLFDDSAYRGTFWANFSTGIGAFIHELGHTFGLGHSTTGIMGRGFDDMNHLFCAFEADHHVHEPAFYHDFGDGRLHLNHQVLKEVTGPNGAHWHMGSALQLIHCPWIAGEAKRSTRGPSVRWNKNIRGPVGYGTYDGEQKDFNQKHEDVERVDLGAVKIRANSFMEKIKCYTRSQIASKSAKNIRSTDDKYWLVLQDNEYVTRVEVRAMCWIDGMRIHTNLRSTRWFGGFGGQLHVLQPDEGFKIHGFFGSRGNSYVGKLGVYCSPITENAPTLPGSRSYVPVSGTIGTIDKVGLGYAEGPHQDFSYRDIPIAAVAIKCGDFVDNIRLVTPEEHNAGSTETDRETYVMGEHVWALLPGEYIVNVQVRSGHWLDAVRFKTNLRKSPWFGGDGGEKHKLVGPTGTRISGIYGTRGASVVDSLGGFYCAITNSDSVPLPQVMHQLSALSDIPFSLLGATQQVPPIIMGDAPFASNARGVVVAVQDNRVQYVNSFDSMEAKQNLVRELETFVYAGAQLFSFSLRSGESLIQMDASVDYSTGSPAIVGVCFHSSTRCSSWFGTYIDTSLHFVMAPHGSVIKSVRSSPGASSVVDLLGEFSPRSSPSSVEMYEINGVREDAGTYDIRLVSQSDFGIESVLLLKKRNDEDLDHHAWQWKQPHVPYPQRWCLPQKMLEYHVHDDREGTDKKTLLHREYVVGGVDVGGAFSKAGSPPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI20</accession>
    <name>A0A8K1CI20_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI20"/>
    <dbReference type="OrthoDB" id="108146at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="64795" checksum="EE8D4044CF01041B" modified="2022-08-03" version="1">MPWRQMLRRAVEVWEKYQVELQGQYSVERLYDLERYSAKTSPLRVAVVLLATPLPCLAVVTLADMVPLEDPSRGLAHSHMFWLRTAFTTTLFGVFIVHQFRFCIDDLHMNNAQLLLISILSGCGATAVGFFLSYLIGFPMPFIIQCAGPSFVVILVIAFAVGWGRLFSHNTRARHQLRNAMGILMVQWYLTLVYPVYNAVFVRLDGARQATFALVLPIIKLGGKNAMARFCKDMEDATPEVVVMNIEIFHALFTTYCMQGTSSMLTVAMIMGFDAVLAWSSLHEVDVLASDIRRIGDKPRSLLRVSDAVASLDKSRIRPVLRTVMRIAKTDPLVRDSGAVRLASSTRSRKTTPPSLIRGRSIVPTENAQSLPLAVASDRHTTVMNSENGQKSEETAHGSSVSPIRVDHPDLLLMKSGIDRLTPQERLEYVQKTLQLLHLTEFVLLVEFVEIIIPLIYGSYLLICFQLPIHEYYTQLHDVSPERLRQILKNVLIYALLEFISFIMLHHLLRRKLRLAPIYQLSFVLETQWSVIQSKLPLWMIFMVQQGLEHFGVDYTFQFKWLRRSHTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIL5</accession>
    <name>A0A8K1CIL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EFHB C-terminal EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIL5"/>
    <dbReference type="OrthoDB" id="2096280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057428">
        <property type="entry name" value="EFHB_EF-hand_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF12">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25325">
        <property type="entry name" value="EF-hand_EFHB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EFHB C-terminal EF-hand" evidence="6">
        <location>
            <begin position="336"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47745" checksum="30BAEFB6F7BC8CB0" modified="2022-08-03" version="1">MKSSHTPPRIAGKVFGDSERASSCLTFDARPVTPEEVRRYRKSYFAEPGARIAHPGLINDLKQIDPLTKHGVSTSGSHHVPDVLANAPATEYQRMQQQRSESTYASLKREPLGRSYSRGHTLPAHMTKPEYAFGISGTFGESAKELLYPSTTLNNKQDDELYKRSHGAVAPGEQKNRQYQWDNAKIDPAKYRFGVKTISLGSDGLGAATCLRPEIDENANKPVVTVKQVEEMRSTYDQLGKPRHVSAAATNLPSDHVFGVKLSKDDETARGCIQGYYTEDEQQPDADLGRPVSYGWHNVTPETRSFGVPSIRSDIPMPSRRSIADCQNYGDDSSSKELLYPEEFASSGIQDSEFAVPRDKTQLRAMFEQIGYKLSDEYFALVWKDTSKSHPNAASLVAFRDALNRFLAAEDMGQSALEEWRQRLESAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIS9</accession>
    <name>A0A8K1CIS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tyrosyl-DNA phosphodiesterase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIS9"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="55169" checksum="CC37AD777CA2D4F5" modified="2022-08-03" version="1">MGASVVMAEPPSKRAKTAAPSDTETKAERLQAAVDAVEEVSVTEDASVDVLFRLTRLKDAPERHNRYAIGLQELFEGEYTQCLLTNYMYDLPWLFASCPRLHDVPVVLVHGERDRHAMTQECKGYGNVTPVAPYLPIPYGTHHTKMAVLLYPTKARVAIFTANFIAIDWHNKTQGVWFQDFELKALGEDDASEEKKQHQKQAAVADFERDLIEYLSTLGTPVVTFCKELSRFDFSTATVALIPSVPGAHTGKAMHKYGHLRVRALLKHFAVAPSDHPLICQFSSLGSLDEKWLFGEFAGSLMPGPTQLASGGSTLPIKALHIIWPSVNDVRNSVEGWNAGRAVPCPLKNMKPFLHKYLRKWTPPSALHRQNAMPHIKTYARFDPKRDGCVDWAILTSSNLSKAAWGAYQKNQSQFLIRSYELGVLFLPSASSHQHLSVVGTPAANTEDSIPTRLMPLPYAFPLTTYNPKEDEPWVWDLVRDEPDVYGNCYIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJJ5</accession>
    <name>A0A8K1CJJ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJJ5"/>
    <dbReference type="OrthoDB" id="106209at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425205" evidence="1">
        <location>
            <begin position="21"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" mass="57922" checksum="05DD82D62D09234D" modified="2022-08-03" version="1">MVQLRFIGLLVAAVALQANAQYAGDDDVVGKVIPYGAAAYENREGEQPLQHWVGPAIPAAKDSACYRKTYRTKKCPVGYNSDNIATCWAQCPVDYPVECGMECLPQNADCTKAILGKVTSVATVALNAASSGMFGKFLSAGKGVQQGVKCGQQIFATVQKVTGYVTELEASGTGNTTTDQFQVLLEKSDLVTYDLPAAVATCLGKPIPAGLEKGNDIMDKVKAVTGQVLEAKKSGTNLLEPTNFIKFVADVGFSSAIPTLKSTQDVSSIKDAVSRGLGCGDAINKVVNRVIGMVQEIKTKDASTTVEALRVAVMGSDLVLKELPDAATGCFKVNMPNAFQKRDEVLKGIHVVLDGVINAASANAPTRTRGRALADEKPLSKADYALKVTEMGLDAISTFDPTGIADMAKEFVQPICGPTLFVGDIDDGPADQALGLRTMEKAFEGSVGDWKKQGDGQIHVTFKSTDSKDVEVVIKAGGQVHSKVKVAKGQTVEWSKPLSEFQGKTLYMDRWRSAILGVPMSSGGSLLAWIPSNAAGTLKLDVNLNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJS3</accession>
    <name>A0A8K1CJS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJS3"/>
    <dbReference type="OrthoDB" id="69682at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF10">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="128"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22095" checksum="D66B8C5691DF1BF0" modified="2022-08-03" version="1">MVEFLLDQGADIDAPGRDGTTALCAAALWGNDAMVSFLLNKGADPNARNEGTGWTALHAAAFQEHGKVVRYLLERGADPKARDSEGRTPVDYASISEAIWPFFAARGCVKSVKSDLVTKGIIRKIVQDQPEHGGGSDYSSESLSAFSRPGSSYTRAQFQPPVALKRQGSLKSSAGRPTGPIDPLGDEAFDSRPSSNQRRPSFQGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK10</accession>
    <name>A0A8K1CK10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011555</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK10"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429842" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="30"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="254" mass="27440" checksum="C1FE1A695A456EC4" modified="2022-08-03" version="1">MVSFFSKLAVIATIVASSVSGLEIGEYSRPSGAEVSSVPGATAPYLRSPCPTLNTLANHGYLPRDGKKITSTMIADAIVEAFNIDPILAKGLVSQVRAKGTIDLAFLSTHNFIEHDVSFAHSDFSYGDDMSALNVTMWDDFSSRAVNNVIGIEQVAATLEDRVKVCNNKPEGCDYGIKQRVTGAIQAAFVLRAFGGKNEETASLDNIKAFFVDERFPDGYAKPSTKVSITKLFSTAIKVGVKTSWLELLEFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKB0</accession>
    <name>A0A8K1CKB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008992</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKB0"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="11">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="141" mass="14977" checksum="E060DD3DAA03296F" modified="2022-08-03" version="1">MSGIFSGGKGGKGGKGGKGGKGVTSKKAPQSRSQRAGLQFPVGRIHRFLKKRVANNQRVGATAAVYAAAIMEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPYIHKSLINKQTKKKPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKJ8</accession>
    <name>A0A8K1CKJ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKJ8"/>
    <dbReference type="OrthoDB" id="129958at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035430098" evidence="2">
        <location>
            <begin position="24"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="878" mass="83019" checksum="EC537303A5D8ABAD" modified="2022-08-03" version="1">MIYGKKLFKAIIAISTLATAAHANPAARESKWDEYGNKHGFGQGQQGSSYRGRSALDTVLGADAVDPAQVASPSNYGGRKRNGNTGLRGVISPKNQADKFSVASPKNAATPCPSSLNAAHPTPAPTTAKPCDKNQIKPTQAPTPVNGGPGKGGYNPTQATTPAPAPTPAKGSDKGNGGKPGAKPGKGGYNPTQAPTPAPAPTPAKGSDKGNGGKPGAKPGKGGYNPTQAPTPAPAPTPAKGSDKGNGGKPGAKPGKGGYNPTQAPTPAPTPVKGGNGAGGDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSGNGSGNGNGGDKPVVPGKGSNSGNGSGNGAGGDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSDNGSGNGNGGDKPVVPGKGSNSGDGSGNGAGDDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSGNGSGNGNGGDKPVVPGKGSNSGDGSGNGAGDDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSGNGSGNGNGGDKPVVPGKRSNSGNGSGNGAGGDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSGNGSGNGNGGDKPVVPGRGSNSGDGSGNGAGDDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYSGNGSGNGNGGDKPVVPGRGSNSGDGSGNGAGGDKPTDKPTDKPGNQGPGKSGSGSGHGAGGDKPTDKPGKGGYTGNGSGNGNGGDKPTEAPTSAPTPAPTPAKGGNGAYTPPTSTPGKGTPGKGGYNPAPTPAPTPAPTPAPTPAPTPAKARTRHQRALQAREPQARAATTQLQHQQRAATARTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKP2</accession>
    <name>A0A8K1CKP2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKP2"/>
    <dbReference type="OrthoDB" id="166612at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479035" description="TRP C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="698"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="742"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="835"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="914"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="TRP C-terminal" evidence="4">
        <location>
            <begin position="675"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1019" mass="108172" checksum="0F9BD9826FF48155" modified="2022-08-03" version="1">MRVMRSSVVATVTLLGVTTARPTPPDAIVDVQLDELPHQVQNGPYKQVSEELYVRQLEHLGVYFTLQRQTSKWTLSGYQCVAPETEQGGVCEQIAQSEVTPLAVNVGEHPVPYLVHPSTVSHGRQLQFSNPGLPEPPLIDGMPVYYNCGYSGANDWCCSEFNAAAGGANCWNLNTCTEDYMFWSGQNMICCSGNMGSCVLTYQPPMPATPAPPPSSASPTSAPPFSVITASPTTTAPPATSPPSTPEPSTEAPTPPPTTEAPTPPPTPPPTTKAPTPPPTPPPTVAPTPPPTPPPTTEAPTPPPTTETPTPPPTTEAPTPPPTTEAPTPPPTPPPTTEAPTLPPTPPPTTEAPTPPPTPPPTTEAPTPPPTTPPTTEAPTSSPTPPPTTEAPTPPPAQPPTTEAPTTPPPPTEAPTPSPAPPPTTEAPTAPPTPPPTTEAPTPPPTPPPTTESPTEAPPRPTEGSTPPPARGKELAKRVATGTGTISSDMSESKDSSGSDHSKRSASSEDTEEHDENAADLAHLEQSLVDLADATRHLRERISESANILVATAVTVNVVSSVITAVTSGTAAVSSVASITSIAIAGSQGLLHIATGPLSQGFPAADLSGLLMMLNYLQFIAAGSHLSLPGAPDFFFEFTDSLGWSHFQPISRREAEPEGVSSQHMGNFSAAEGDIIAGVLAYAERLNVQPEELFTKTIIAFGTVVGSVAAVVAILYALVRCVARKRLELVIQRLKDLPRAKLLLRLLTQSCLSVCLMSEYALSMTSSFQMRYYQQNTGGYGAFATATVALIVVCFGLIVLGVVKLWNKSEKELSDPDFKFAWGAYYKYYRFESRYFFVAKMGAEILSGVIIGLVSDVPSQLTLLMGLQLSMFLYTVESAPYSVSFQTFCSSTAFVMKMITYALISSFLTPSTDVGMRDCVGTLVIVLQVTLLLLFNSRQLHILYKQVRYLWALRQQTRQLKRLEQAERDEQNAMMLMMSTSTALTPTYDTTPAEFGLLKSKRNAMTVAAPPPPLPVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKP8</accession>
    <name>A0A8K1CKP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate dehydrogenase assembly factor 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKP8"/>
    <dbReference type="OrthoDB" id="201362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524:SF3">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="124" mass="13638" checksum="F813EDB7C819D414" modified="2022-08-03" version="1">MAMNGGKRVVTALRAVSRAGVRQSSPWSARAVVGQRWISQSPLRLHDDHDHDFVPLKQGDGAAKTAVLHTEFDDDDDEDDEDMVSVVAVGPNGDLEYGGPTHGGKYKEPTRFGDWERKGRCSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL98</accession>
    <name>A0A8K1CL98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL98"/>
    <dbReference type="OrthoDB" id="4703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052416">
        <property type="entry name" value="GTF3C_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15052">
        <property type="entry name" value="RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="413"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="35"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="635"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="696"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="799"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="975"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="645"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="709"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="817"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="865"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="980"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1032"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1075"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1085"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1120"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1136"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1188" mass="130271" checksum="31472EE909228BA7" modified="2022-08-03" version="1">MMDLSEWCEQVPHGQYFQPIRLTLVGVDAQDKWEEDPATLKTSGVNAAEQEPPAEELNPAEPQTSSASPDKASTQKRLKQRKKDSKAQPAVVSSEKSQTVERDDGSVVFIPPFQSVSIGGNHTALNAGGPVWAMDWLPQPSHADTTTVPESVPATKKGKASKENNTRKAGASSDNSSHRAQDNSAMSTWRLLALSTHPPCKVVDDKMVKVTPPDHYFDLPESGRGLVQIWAIPIQSASTDKSAEATQPRRLPRLVYAIDHHSGVAWDMQWCPLVHKFPRSSNIHDKQLLGVLAVCFGDGSLQVFEVPTVPAEKLAAEPKEDVVGRLQPILQGKVDSVIQLTVRWSPHHWNLMLTGSSDGSVALWNLQEVYGSSRNTESDQRQRNELEPQRRFQDADTVGKQEAFDWGWGWVAIRAVCWSPYDENLFVTTGNDSMFKVWDIREPRISFRSHRIRSTWGLALQWLDDTSVHISGDQGSIYMYDILSGSYQKLHFHPQIDSPVWDMQLARRAALPLLISSCAAGSVRLAPAKKLFRAPQYSIEICRLHGEKDANVEQPHKALTLDFTRRIVSVSAEAISPATREFCERDASLHRLRVSTFMANEFPCYVATGGHAGLIIIMEMQNELDQVMDKHFIASNKKIGRPRKSQASSTKKGWNLSQIGQAKPKKAKTEAKAKRSSGGVKLSSFVKAKKMHTAISKYKPKQSMKAEPIESEAEADSPSEPEYQEEEEESESGSEELSLADDNSDDDHARESDDDFDTDSDHVDSPQTAADARMRSEYQLDLSEEDAILLAIQMSEMEQRRSLEAQKTSRKSTDNGAATKKSTKATSSTPASRSKSKSSDNAAVESTRLEKKITSSAGKSKKTPLRSSGRGSKTNTPNGTSSGGVPSTSASKQSAKSKKRAPKDESSISPMVASAAADDGDDSKSRLQATKVPSGASESQEAKVGEEMDQTSIQMLIYQKGMSEEDALREAIRMSEVGHMRRSNRKRKAPTPDRDGEVDLEMTAKPVPSKRTTVSKRSPEQIVLVAVSENEEVTRRLEFGRDGGASQPATPEQVVVAPPAISSDVKLPAPKHMTPPKSSAASKSSGKKPAARTSTTKKAKKASYSEKPSEPSADSVEPELTSSFSTPTAQKKATKRPSTSSKSRTSTPSTSSRKRAKSTKRSDNSLADLELSEEELLALALQTSQIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMR4</accession>
    <name>A0A8K1CMR4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMR4"/>
    <dbReference type="OrthoDB" id="70598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="16650" checksum="C87A6C0BE8DD406D" modified="2022-08-03" version="1">MLSLRCALAARPALAKTATHRFLREEARTGVRFLSSEPSIRRPKALKVKKSEARRRVEPKPKADNNALVEQQEQAQAPVEYGHGPFTQPQAPQTFGGMMKESFFWGFGMAIAFTFVGVIFSAMEETDEAGAYMATEVISTADEHRDEQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN93</accession>
    <name>A0A8K1CN93_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN93"/>
    <dbReference type="OrthoDB" id="65833at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="41877" checksum="9DE572C6A5157418" modified="2022-08-03" version="1">MVTQASEGRTIMMLRELETSLGNEREWHNIQKTVVTAFVKVVSVLSAQASEISALKEQLQRVEAARKKQEEEGKYITSRGLEKRCVALMRKWAEEHAADDLKTREVVKEAVAAERRKIEEYQCRLHEEWTSWMSKMEEGAKEMRQKWSDRSLRRTSDRKEDEFATRFDELESETRRLEDKMDRQFSLWRQEGVKSLIMKPDRAEVVSIIEEKTAEAVNTALQLKVTSLEVIRAELDQSKQQYKECYDAVRSLTESKAAKSDVTQLKTDLRDLLFVIEAMQREQGELREFVQPSNQRPRHQNDTDKAMARVNEALKQIQRSMEHTAKKGVVDDLMEQLTSVRRQLRSEMYQARYVRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNK2</accession>
    <name>A0A8K1CNK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_008324</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNK2"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000092">
        <property type="entry name" value="Poly(A) polymerase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="17">
        <location>
            <begin position="12"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="16">
        <location>
            <begin position="211"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="15">
        <location>
            <begin position="359"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="15">
        <location>
            <begin position="417"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="492"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="104"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW65682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="61062" checksum="54B779A83443F686" modified="2022-08-03" version="1">MTGASRTARSLGITPPLSLDGPTDEERDLQVQLDQALKAYRLRETDVELKHRETVLAKLREVLQEYAVHEGCLKGMNEDAAMDKKVQLKTYGSYRLQVHSPEADIDTLCIAPKHCTRASFFQKVPILLEATPGVKQVLAVPDAYTPVINMKIDGIAVDLIFVSLPMESIPEDIDVLDDKHLRNLDESSVRSLNGVRVTERILQLVPRQDRFRSTLMAVKYWARLRGIYSNKLGFLGGVNWAILVARICQLYPNALPATLLAKFFRIYHLWAWPNPILLDVASNTPNMGFPVWNPMTNPRDRAHLMPIITPAYPAMNSSYSVTQATLQILKREFGKAASRSFEIETKKGKWGSLFAHPVFFQRWQHYLRVQITAKDVSDFSKWFGWVESRLRYLIQRLECVQHVRPHPFARFYDVCDEKGEVASTWFFVALSFHVPETTVASSPSPAFQLDLTTAIRDFASYVDQWDQRRGGMDLEIDHMQRQQIPEWVVQATEGGSADGKTTGKTRKVEQCYPDEDTPHSRSTTKRAKEGAKEVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQF6</accession>
    <name>A0A8K1CQF6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007584</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQF6"/>
    <dbReference type="OrthoDB" id="70398at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="13"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter family G" evidence="9">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="8">
        <location>
            <begin position="271"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF19055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="555" mass="61782" checksum="609D505995664221" modified="2022-08-03" version="1">MDVIAGRKTGGKIRGQIMFSGHPATDLVTRRSTGYCEQMDIHSDASTFREALTFSAFLRQDSSVPDSAKYDPVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLVMGGVRKVADTGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGDRAGELISYFEKVPGVSPIEEGYNPGTWMLEVLGAGVGSTANEDIDFVEVFNASEKTVLLEENLSREGVGRPSPQVEAVLYKSKRAASEWTQSKFVTKRFLDLYWRTPTYNLSRFLASIFVGLMFGLSYLNVAYDTYQGINAGEGMVCITAFFMSSITFNSVIPFAAQERASFYRERTSQTYNAFWYCIGATVAEVPYVFASCFAFMVLYFPMAGFAGEGKFFFYWFVVSLQVLLFAYVGQFLAYALANIELAMIGSVVFISIFFQFLGFNPPPSALPTGWKWMYQINPPRFSFSVLSAVVFGDCSADDPGAIACQKMDNLPPTVPSGLNVKEYVEVVFRDKYDDIGFNILYLLIAMAVLRVFALLSLRFIDHQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQN5</accession>
    <name>A0A8K1CQN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012051</name>
        <name evidence="5" type="ORF">Poli38472_012054</name>
        <name evidence="6" type="ORF">Poli38472_012060</name>
        <name evidence="7" type="ORF">Poli38472_012066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQN5"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="3">
        <location>
            <begin position="202"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="30036" checksum="BED3384CD8362111" modified="2022-08-03" version="1">MNEMTPLMQQVPYMVLPGNHEAECHSPACLLSTFKKDHLGNYTAFNSRFKMPSAESKGVKSMWYSFDYASVHFTSLSSETDYPDAPSNSYTLTHKNGGFGNQVAWLEEDLKKAAANRANVPWIVVTMHRPIYHLEQVDANGAPTDYSKNLQSAFEELFLKYNVDIVISGHRHRYERQMPIARNAAKTDGVSSDKKTYTNPKAPVYLVSGGAGNIEANELNNNKASWHVVQSKDYGIMNVHVGPKSMQWTYINSDSKKVVDQFTITKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQT1</accession>
    <name>A0A8K1CQT1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQT1"/>
    <dbReference type="OrthoDB" id="129194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="719" mass="81751" checksum="BAD632BCC0B78271" modified="2022-08-03" version="1">MATEPDGSWLYGRYDDLSPFINHHDHHACSARSDSGECKLSLVVSKPLSGRSPQYYRQLRNDLLVAGTLGFGSSTSAPWNQAVQYHTNDESVPNSVTRTLTPRITFDFGFVTARDLEWKNTLCHLFGYDGRNSEFLSECKLLQEQFPDNKAHLPSIPIRFIIPTWGVDSLGDQLQILQKLIILVQRTLERTKQAEESHPERPRFKLETMIIEVPDFYLTSKIVRQLQALMTLDVKIEFLVPPKKTVDENNVEIPGWRSAWASLLFTVFGHPQATIVSPKPVEKFVLTFAREAPVTMYEAFFSVVVHATSVTKIYVMREYSYVSPTQWRWLLYALFSRASTTSVKEVGSLTHPLLWTFEDVDVASVVNATHPVTQLHPDSTSADDKYLGIVRLQQGAKIQISKDPSDTIEVTNPDGQSFEIIRRGASGLICILVPGYGYGWVDRATTYEKRMRFSSSRPSPSPSPSLSQSAVECIEAGERDFYQHEPAALVQLWLPHIGRHLKDLRVSVARDAHDEVLQDILAHCPNLESLTIGNFELKSLQLLQDAFEKHACQIKSLIMDWCSTDVMALATFIASLADRKTVISKRLQRLELSQQMACHDLPMYLLCVLHFNDRLHHVRAYMWPCQVRWFNEMAVKDDYDLRTRIVGISLPIEAKSAFLSVFSPINTASCTVKTALDRDVISTIFEMAARPVQRKVVIEETPHEEEEPDHDHEMHEHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG2</accession>
    <name>A0A8K1CRG2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG2"/>
    <dbReference type="OrthoDB" id="124765at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="435" mass="49080" checksum="F4F0C32E93C66D6F" modified="2022-08-03" version="1">MSSRKTTKMSEELSDVETLDAVVAFIDDFYEADAPLIEGFSSSSEDAVPNATSSSGGDADASSEATASPPQTTTTRRRPAKAPKRQNHNRARDQRKEELSLLRQEEEALRVRLLQLVMAKATGEFERQRSVEETDTRPEALRQEMLAVWKDMAMRQYGRRKTAETENTRLRDQVQSQRKVIQSLQSILVRHEKPQLAPTPNWLAYTAGSDSVHRTRVFVELLTDLKQAHSVTNAWLDSSRANPLTGGKFDDTRVATLSPTQHALEMIYARLLPIDFRTAADTYWHTGINEHCQMFDIYREHAKVEGRDTVLYSQIVHDGDKSTVRLHTHVSVQKFEEENRIILLIAARPEAIHIDGERVTDVTMTEQYWVVFQAPEGKPQNACLMLSFGRANFKLDAAVASATHAVSTLSTHVHERISGHLNSAVECMEDRILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC7</accession>
    <name>A0A8K1CSC7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006133</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC7"/>
    <dbReference type="OrthoDB" id="192247at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050804">
        <property type="entry name" value="MCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46236:SF35">
        <property type="entry name" value="MATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46236">
        <property type="entry name" value="TRAF-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="F-box" evidence="9">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="145"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="593"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="682" mass="77190" checksum="5518525E255382F8" modified="2022-08-03" version="1">MTNADASKQHAHASHAKKRHWREGAGGAFVRPASPVRSDLKCVVVDAKPRRPPPSFVQLLPLEVTALVLAFLDGHSLLKCSAVCRVLARLSHDRHVWKNICVKTWPTLNTQTLPQLPGAPDYDLIRLYGGSWRRCFVEQHRLNQRAELRVDIPNFSQLPPGDRVESETFVIGEHRFCLWIFPHGNPNEPQYAGRVLSVYLVLTDLDRRPADWLTCAVFSLCVVNHKDPTQNIEWHSCLVDNKFDARLNNWGVHSLGALKTIRNPEMGYMVNDTLSVSVRVRLMSITFRVVMEDDLKRHHHLGLTDLTTTKTITLPFCASLQDLLHKLESEFEVDPDAVNIWCFNQPVISGQALRPRKLLTSTKATKTRPMFGHLLADGIDIDAYSCCQIYVERKNEDDAPLNASSMNDSATDMDTSSDEEEATESLPSASRYLFVKALHPHTQKLDYLGRYCLDDTEPSTSSLYESIAARLGCEATDLLLFKEEITPVVFSGPITASPCAAVTSCFDAADIVIVAHKRSVGDGSFDRVLRSLLLSQYHAAEDLLFHRLQPPTLEQIENLAERLDIPKFRVRSAFRKCHEDGQSTLRYIMEGRHLGFICDCCGETDFQGPRFNCTSCSDYDLCRNCHVTSREVSHRYANVDGKWQRIYDFREHASTHGMREMLPVFFQYEAQVPSQHQNAAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG2</accession>
    <name>A0A8K1CSG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007589</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1116"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1186"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1253"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1351"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="81"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="774"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="714"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="722"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1377" mass="153652" checksum="E301D9A5698EF618" modified="2022-08-03" version="1">MTEPEQPLKPTIEYTSGKALMVHGPEVLHSHVSSQLETALGRAMHQMEVRFHDISVSADVVMASSKSTTNELPTIANELRKSVGGIFTKNHTITKNILKNVSGVFKPGTMTLVLGQPGSGKSSLMKILSGRFPMSGHVQLSGDVTYNGAPTDEMRKRLPQFVSYVTQRDTHFPTLTVKETLELAHEFNGGVHFSKRLASTLSKTAPEETKAAVEAVQQLSEHYTDVVIQQLGLENCQDTVVGDAMLRGVSGGERKRVTTGEMQFGSSLVTFMDEISTGLDSAATFDIIKTQRSVAKNLRKTVVIALLQPSPEVFALFDDVLILNDGEVMYHGPRDQVESYFADLGFVRPPERDVADFLLDLGTRQQRRYEVTRRDASQLPRKASEYASIFRQSRIYNDMTQYINGPHDPALLEDKKELFELVPEFHQSFWASTRTLMGREWKKMSRNPAFYIGHLVLLGIIGFLNSSVFWQFDPKDPQVVLGIVFGTVQFLGFSQTAHIPIYMAERDIFYRQRGANFYRTSSYVMAHLACQIPMSVIEAIILGTISYWLCGFVAEAGAYFIFLLILVLNSLIFTAMFFFLAAISPDLHVAEPISFVWLLLFALFSGFLMAKDQIPDYMVWAYWLNPIGWGVHALAVNQYRNDHFDVCVYDGIDYCKEYGMQMGEYTLRLFSVDPARAWLWYGILYLAGGTIVFMCLAALFLEYKRYESPHNTMLNNEDEVSSNKSTMTDSDSGAGSGLESPVPYGLVSTPRADGVAIIELPSSYQHRRVTPITLAFRDLWYSVPNPTNPKEDLELLKGINGFALPGKMTALMGSSGAGKTTLMDVIAGRKTGGKIRGQILFNGYPATDLVTRRSTGYCEQMDIHSDASTFREALTFSAFLRQDSSVPDSAKYDSVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLVMEGVRKVADTGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGDRAGELISYFEKVPGVSPIEEGYNPGTWMLEVIGAGVGNTANQAVDFVEVFNASEKAVLLEENLSREGVGRPSPLVEAITYESKRAASEWTQAKFVTKRFLDLYWRTPTYNLSRFMVSIFVGLVFGLSFLSVEYDTYLGINAGEGMVFMTSLFIGAVTYISVIPFAAQERASFYRERASQTYNALWYFVGATVAEIPFVFASCLAFMIPYFPMAGFTGAGNFFFYWFVISTLVLFLGYVGQFLAYALPTVELATIVSVLFLSFFFNFMGFNPPPTALPSGWKWMYQIDPPRFAFNVLSAIVFGDCPEDDPEALGCARLNDLPPTLPANLSVKEYVQTVFKIKHSDIGINILYLFIAIFVFRLLALLSLRFLNHQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSW3</accession>
    <name>A0A8K1CSW3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 69 ARM repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSW3"/>
    <dbReference type="OrthoDB" id="191673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048732">
        <property type="entry name" value="CFA69"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048733">
        <property type="entry name" value="CFA69_ARM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21049">
        <property type="entry name" value="CFA69_ARM_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="2">
        <location>
            <begin position="35"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="2">
        <location>
            <begin position="260"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="2">
        <location>
            <begin position="608"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1048" mass="118093" checksum="3F22C26D986DB220" modified="2022-08-03" version="1">MECARHRCSASVPPLAGPAERPPSTESTEEGFRKLFAAVADPQTQELHQRHLALTKNVLYQNELGWKLAELPLVNDLLVLLRDKVLDGVEAFDEQLLAALELCSRPFLRQKSNEEISNPTLLVGIVPTLAQLLSFHLVDVQVAAATALYQFAIGACLSRPSSKTKSNNLTEADDLRTPTRVFCQNLMEETDTIDLLVAVFHDLFPDDEEPDDELREQVSKQVSHEIRPLTPSTATDDPSGMGSELLAQRASRLDRLLFPLVELVHELSSNQRCAEVLVVTGALHYIVFLLDGIASTQDELLPLCLTTLWNVLELCEDKMKTLTTCSTRRELLIAFRLRNATYFLSNEFTLQTLLKTLERLLMQGYRRQDKEMRNECILIFMLLAKRVRSLELFHTSGLTTCLLTYATASEFARKKTNGSNSQNASSTALGSAIVADFHHYATNSDEDLEFKQSVWLLLSIICAGHEGNLHTLVQFRFLDVLLNYATMNEATQQHRKTLGATTKNPSKTASAQTYSQAQLQLLQTTALTVLNSIGGLMLEHFVEINGHRTMIEFLHARNASEEIQAAVWMLFLQLTPSERPIQDALGHLGALELALSTFQSPPSRHTFMIRRDAILVCSQLCWNNEENRRRFFAAKGVTSVVRYLEYDSAQSVLHENILVGIIEAVRACIIGHSDSELAFLRADGVLRLLDIVETAPKVIRNQALAALAEICVNPGAIPSYAAWRSERREASYSTANQMLLRIYADEEAVEDKQQQQRSESDAEWNLVSSTNQRSSAFQSITTCKSPFVIYADGTNPAEDTASMERSASPAFARLKEALKAAQTLATGSHATSPRSLFELQHDEFHPQLNLKAKIHSVLANMSFNCPQDVEMTAKELVMIEIAKEYPTFQIGEMWQNVELTLHAEGVRPIYADALYIRRQIEEAYNIAVCTKNAQQEVVSRELQGQERREQSFYEGILRQKQQEEQVEAFHRANRRQNSTMKLHLDAKRTRLEFMKKQDPTAFAAYEREMQRTIQDPPPVYMEELSSVAQKEKELRGRLSTIVTARSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU96</accession>
    <name>A0A8K1CU96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein 54 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU96"/>
    <dbReference type="OrthoDB" id="756370at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049546">
        <property type="entry name" value="WDR54_beta_prop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21031">
        <property type="entry name" value="WDR54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WD repeat-containing protein 54 beta-propeller" evidence="4">
        <location>
            <begin position="88"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="286"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="41385" checksum="8982E5BB0544459A" modified="2022-08-03" version="1">MATSTLNDHVLLLGSNQESELFVADAATGGQLYCFKNCKTSRFGVQVVPRTDHFVGIQDGKLALHIWTWSKDMPVLKCHTAEKMGPTAVTKCGNFFFAGAQSGKMYVWDVKTGELVMVWDAHYKGVSAVALTSDDSHVITAGEDAVVHVWRLMDILDEPDVTASFQQGLTPLVSWTDHVLPVTSIHVGLGGVNARVYTSSLDRTCKIWSLNSNQCLFSLTCPSFVNVCLTDPMENRLFLGCGNGKIYVVDLNAAASSLTAATARLVSTNNDNATPWGSDALQPDAFEGHEVGVSTLQVSQCGGFLVSGDESGVVRVWDSVSRQSLRTIKLFRGAVSSLLLLPKPRNLYHKVKLSATARLSEPVALPIAPFRKYMGAGNSAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUG9</accession>
    <name>A0A8K1CUG9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUG9"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026">
        <property type="entry name" value="PIGMENTOSA GTPASE REGULATOR-LIKE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="30717" checksum="FA17F197EFEEB3D9" modified="2022-08-03" version="1">MADNIEDSAVNDFLLILEEHRKNCERQGKYVEADVAKKRLEELKVHEENRRKEAMRSRQIAERLGVEEAHMLEFQQFNQVWDRKMEEYERNVEELVVNMREKHKTELLEYQKKLLEKQQKPKFSKDLLNLRRIEEHLARQKDYNEAHKIKLKADALEAWELEKWKNQKQQEMLQREVKFKQRQKQDLDALLKRIQSGREEQKKQRQVDLERLLQRYQNVKAELLQQQNLERIRYEKFSQRPGATQAILQGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUI4</accession>
    <name>A0A8K1CUI4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUI4"/>
    <dbReference type="OrthoDB" id="9974232at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028131">
        <property type="entry name" value="VASH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750:SF2">
        <property type="entry name" value="VASOHIBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750">
        <property type="entry name" value="VASOHIBIN-1-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14822">
        <property type="entry name" value="Vasohibin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR628131-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="482" mass="53608" checksum="7E6D0FB325755FD4" modified="2022-08-03" version="1">MGPLSEPTPPKLPTFTTKTSIKTRLQAIQNYLNALEYALRMVKQTTLLLFTCSLRDFDRYNYTGTLYFDVNKNRSFKSIVSTAKDIVSEMLPIQCLEAVFLAAYLTSNVADLERFPISFKTEAGSSVHRHIILAVRHQNNKWGALGLSRSEKLMYKELRFNSMSELVQEYCRCFESVCHSVIKLYIGFPFPHDIHSSEKVEWRALNLSMTENPWTDIASHLDAFAKEAADILSFKRAKGTLPSSFLSKFPLHTPEAEHGKKSPEKRKQLSANSLDFPPVMLCDEDETASPPPAAITPSPEKDDTKKPILVAPDQLVFKRAVANQAHMLPTNIFLQNTTTSAFSIEVEDPSGQLEVVTKATAPPAKSQQEETAKSDAPVKPTFRVSARGMIVIAVRCKQPTETPATACSDSSAQSTQRKTTGELKRTKTPRGGTQKAAEALVPDQNALRFTCYRLLKSTEAEQSNEAESTETYTTALPFIITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUM6</accession>
    <name>A0A8K1CUM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED6</name>
        <name evidence="8" type="ORF">Poli38472_001318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUM6"/>
    <dbReference type="OrthoDB" id="344220at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="256" mass="28899" checksum="A636756BA98ECAAC" modified="2022-08-03" version="1">MEAVAHVDDYNASFHDTIWLQSFPLNAQTVLHYFALSPFYDRSCNNERLKMQRLGLDQLKNMRGIEYELLPNAAKQLPQQLFLIQKQRRLGRTQVKPLAVYYVLDGRVYQAPNIHAMLTSRLKKCSHRVNKAFHALAAGVRFSPTEGYAWDFSSEDNKAPVIPSEQLQLKLKQKFEKMEKQRENSARVDSILIRLMKKHAPEIVEKIESRDEAASQIAAGVTVTPATAAPAAGQPNAGTKREADQGQDAAKRQKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUW4</accession>
    <name>A0A8K1CUW4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUW4"/>
    <dbReference type="OrthoDB" id="75067at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038863">
        <property type="entry name" value="Put_Complex_I_su8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36401">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36401:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="131" mass="14304" checksum="686406E34404BC45" modified="2022-08-03" version="1">MSSRTLSQALRGGVCRATHMTRGGGGHHHRPPPPPFARLPAPAQPLHEHAELVWNDGVAPETLIDFDAPHVPQYRALKHLGYALGALATLMGVVTLYEPNSLRQAAKRGDHLPDLKWELGQADEPEGEMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAU4</accession>
    <name>A0A8K1FAU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial splicing suppressor 51-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAU4"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF2">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="1">
        <location>
            <begin position="46"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="28800" checksum="90FDE6E48DA03A7D" modified="2022-08-03" version="1">MTVLTESRALTLIECVKRLKADDYSESTGLSSVDAKNGAPSVSNLLTLPVDGTLTIHLVGADHREGNTVAETLGIFDQFFQYLAVDDRCYETLQLVLVGPNIAHKLHNDSHESTHIDTTATLEAKATAAAIQIELSYYVGSFDDYYGETDQYVRPDLAVCFNAGIWGYDQWLPTLRLLVHQIQTPLLITSYNENEASDDEDVLDDSVAPPRWFWRAEKNPFGSLTHRSTRNEYGSILRENDFWMCVGPSSMQSVVVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCZ3</accession>
    <name>A0A8K1FCZ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW55007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCZ3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442879" description="Thaumatin-like protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18028" checksum="DA2B2E1838251E56" modified="2022-08-03" version="1">MVQLIRSLLTLSALLLVTPASAVNVRFTNNCPKAIDLQHASGMFSSFKTIAKIPMGGARAQAINKGTHSFRFAGSSAAAEFSVTATGVTYDISVDPSAGQCNTSECAIISKLGMDIAPKKASGASCRPVKCPKTDKAACAAAYDKEKQACATSTDIDVIFCSKGRRLRSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDP3</accession>
    <name>A0A8K1FDP3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDP3"/>
    <dbReference type="OrthoDB" id="161325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="40445" checksum="458FA79C2D333D21" modified="2022-08-03" version="1">MDGVRLAASKVALLVGLHEYGDVSEAILDYVYQGHEELLESDAKTLQLRIVSQDEEIRSLVAKTGKKLAPQLKEILLWTEQRKETTSLETAQELLKGVDGLVATAQKKQKLVAEEAAEIKRLISERIRLSYGARNEDVALQTYEKSTGCTVRLTNELFYFLLFPNVDDSSTELDFSALERQIRTRVVSKGQILRSNEEESEGDAENSEGGAYFSICGMVDGVTDTLEIMEDDDWQLVPIVIEVKNRMRAFRVPPPLYDHIQMAVYMKMVDVRAGDLVQCLNNDRTSIHISRVSLDAYPLSSSSMASAGLWVSVLLPRLYTVAQTIYKFRRNDRLRLAYLNGSESERMEMLRRECDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGJ9</accession>
    <name>A0A8K1FGJ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGJ9"/>
    <dbReference type="OrthoDB" id="10254304at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03483">
        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000109">
        <property type="entry name" value="Related to MLH1-DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="235"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="513"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="824" mass="92948" checksum="5A82CBCBC4E9318F" modified="2022-08-03" version="1">MGTTATSAPTPLAAPQRIERLQADVVNRIAAGEVIHRPANALKELLENSLDAGATQISVTVNQGGLKLLQIQDNGKGIHREDLEIVCERFTTSKLRKFEDLRAISSFGFRGEALASISHVAHVSITSKTADQPCAYKAHYRDGKLIAKQPGGSKDPVPCAGKNGTQIVVEDLFYNLSTRRQAFKNTSEQYQRILDVVQRYAVHFGSRRVGFVCKKHRDPSCDVNTLNASSQLDVIRQIYGNKLSTELIEFEFDHPATSTAQRDLEFSVHGWVSNANFNVKTSNFILFINERLVDCTSLKRACEYVYSLYLPKHTHPFVYLSLRMPPHNLDVNVHPTKREVHFLYEEIIVETIAKQLEAKLKGSNESRVFVVQPITSMMVKSELKGKGRESLPLTASTQARAVESDDEEEEEDEDEEMAEQEKVSGKKTGRKGVQSDGEEDDDDDEEEDEDVEQASQAKTASQAIQINLSQKATPNSKKYQPSKAPQKLVRTDHRSNTIDMYYFLESQRSSHASLSQTAASHAEDEETELADSPSTNGKKRRLSETWDEEHGEPEASVDSSRRESVEVATQSPQLLTSVQNLLTKIEQRKSKALEKMFREHSFVGVVNRQYSLIQYRTKLYLVRHRDIAYHLFYEKVIQQFGHFNAMQLPVPLSVYDLIYDALSNPRNGYDEEDGPKDQLADDMKQLLVANGPMLAEYFALDIDSQGMLRSLPRLLGSHEPSLHSLPEFVFHLATEVNWDEEEPCFENVAQVLAQWYSELWYPTKPEQSALVLEHVLFPATKLSVKSTSSTPPTSGFSPPNELNDSAIMRPIACLTKLYRIFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHR7</accession>
    <name>A0A8K1FHR7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHR7"/>
    <dbReference type="OrthoDB" id="91802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="376" mass="41408" checksum="3AC180E767174CC1" modified="2022-08-03" version="1">MISKLFSPLTLGGKNPIQLQHRIAMAPLTRLRAGDSAVPPAFVAEYYAQRATPGGLIIVEATDVSLSARGFFGAPGIFNQEQIDAWKVVTEAVHAKGGIIFLQIWHTGRYSHPSLQPENVQPISSSSNMPLDDTRVVPTQDGPKPLEIPRALETDEIPLIVEDFSKAADNAIAAGFDGVEIHAANGLLLEQFLFDGINERVDKYGGSIENRSRIVFEILDAILETIDSSKVGVRFSPFNITCTQRDSDPATHYKYIFEKLNEYDLAYAHVIEPRVPHYPNEMAPEEGATAYFRKIYKGVLVTASGYDRQSALDTVEACHADIVAIGRYFISNPDLVKRFKLGAPLAAWNDSTFYTPGEAGCTDYPFLDEEEIKSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX2</accession>
    <name>A0A8K1FHX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHX2"/>
    <dbReference type="OrthoDB" id="31154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437:SF1">
        <property type="entry name" value="PROTEIN SREK1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437">
        <property type="entry name" value="SREK1IP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="29846" checksum="5E02756DD9313DEA" modified="2022-08-03" version="1">MPASAGRVRMPHNNRMHSSAALKMTGIWTNTIGYDPYAAEGEEKKEVSQSSYEQAQGLMALAKLSNKSNDVRGACKKCGMLGHLTFQCRNFLDTSEKVQAPSSSDSSSDDSSSDSESEAEKRRRRSKKAKSSRGRSRRSPSASPESRKRRSRSPSGSPRRQSRSRRERSPIRSRSPRARRADSRSRSRSRSLDRREDRRSPRHGKRAARDRDEERRRRSDSSDESPERRKKDKKHKKSKRSSKKESRKHKKSSRKSSRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIB7</accession>
    <name>A0A8K1FIB7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIB7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="478" mass="52824" checksum="0255FA84D4F13CCC" modified="2022-08-03" version="1">MESDNVTRVMAQWCLVPTTTTTTVKTVVETTRLAPKMLMLALMYALAQSDIPKRMVLPMACRLVAKSLPLPLQTLLVRFLWKLRVSQASPTPEQAKTKTKMTSAYEKTADAEVAALTVTMEVPQAVEDTQDAFAIQDIDMVPPTTEDEEQSHDVDGDGAGFYTMESSSPPVCVPCMVAVFNARRRLPGDPVVEVKPHKSCNRARVPARADALVLPLPLQVKPFSVGEGVSVVVDDDGVLSDAETEAETDVESDFESESKSKIDLEAADDAQAPLIRFLLDFDAARAATRTAYVAYATAKDHLKTTLGHGEDDGKRKRYPRESVRSMRLAVQRARQAHERALAWKETVMSDCPSWTSCDIGKDEDVNGYCKVAVPEQLVTLRYSILVALAEDRVEEARLVLDEAAEAVAVGAKPRRPSTARAMKTNKSVHCEKPRLALGARYCAFQRYLRARSVLDRAEDELHGYRSRLLPCRSIGEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIU4</accession>
    <name>A0A8K1FIU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cystathionine gamma-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIU4"/>
    <dbReference type="OrthoDB" id="10047078at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051750">
        <property type="entry name" value="Trans-sulfuration_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="60062" checksum="BE17126E44E70A95" modified="2022-08-03" version="1">MTSYQNAAALLQAMPLPLGTSLPPNDPHAVSVSMPLWEHVVGYEEGRPEVMNALACGYPRFFRHPFVQKLQAHLQQTLDAYKEVSKTSTDDWELMVVPTEATAQRLRTFLVTQEDVSEASKANVSVHNVQNGLVWAVVFQKELLTAASRYWQHTGEILTSRHAEAVLKTLQSSDQATTLRLKNTDAHVALRQRIAGLYFDDATAAATASRQNVFVYPTGMGAIFAALRLLTHFDPKGKAILFGFPYLDSLKLLQRSQWCPNGVHFFPVGGDEQLKQVEEILKTEKVLAIFTEFPGNPLISVPDLERLAQLAHAHGTYLVVDDTVGSYNVNVLQHGTTDIVLTSLAKIFSGSCNLIAGSLVLNPQSAAFSKFSHHLLTTQDSFLFEDDAKALVQASHDLEPRLVAVNATANVIVERLSKHPLVKSIYYPSVADAAAIARYSHFVAPSRKSTKSQGYGPLFSVVFHGGNPVARAFYDNLHVAKGPSLGTNFTLACPYTQIAHFYELDHAEACGVDRNLVRISIGLEDTETLWQAVEVALKAATEAQSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIX8</accession>
    <name>A0A8K1FIX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIX8"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="276" mass="30236" checksum="42E048EA01C053C2" modified="2022-08-03" version="1">MSSIATKTLPSGALIPVVGLGVYQSEPGAETYNAVLSALTLGYRHIDTAQVYRNESDVGKAIADSGVPRDQIFVTSKVFSRSWSYDGVVATVKQSVEWIGGGYIDLYLLHAPGSPEGRADAWRALEDMQAAGLLRDIGVSNYSEAHLKKLAETWRVKPAVNQIELHPWLGRTETVQYCESQGIHLEAYSPLARAQKMDDPVVNTIAAANKATPAQVLVAWSVAKGFITLPKSVKESRQKENWEGYNVKLTDEEVKTLSALDAYFVTCWDPIKDHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ03</accession>
    <name>A0A8K1FJ03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Condensin-2 complex subunit H2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND2 H2 (condensin-2 subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ03"/>
    <dbReference type="OrthoDB" id="10038475at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051306">
        <property type="term" value="P:mitotic sister chromatid separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031737">
        <property type="entry name" value="CNDH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009378">
        <property type="entry name" value="H2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031739">
        <property type="entry name" value="Ncaph2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14324">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14324:SF3">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16858">
        <property type="entry name" value="CNDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06278">
        <property type="entry name" value="CNDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin II complex subunit H2 N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin-2 complex subunit H2 C-terminal" evidence="6">
        <location>
            <begin position="553"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="489"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="613"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="619"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="712" mass="79966" checksum="8F7E2FB27E1A6E02" modified="2022-08-03" version="1">MSSESSRFQHLLQPIRDLSKNWNIDLAQELEEYLDELENLTIAFDANEGPSAVVAKKSVASQVQLMNFAEAALLIQGTSMIYSRKVEYLYALVFQTLAHLSKQQEDTHANLQRQRRGENPEDDGDNANGGDDQDNSDSHLDILANPLPIYEDVDEARNITLKRPSSSVRNAGQSRPDALKTKNSIQASIALMGSLVPDERDHGETFKLLSCHLHPSGVLMLDEASRKYLKDEVTYAGASKRMPPTPAAPRTSLIFDEPWALDDNRTSLDHGTKLDFDGVASDDDGGDDGHYDFDDPADGGDVDPFLAPPEEVRATTTTRTRRKTTAPDAKDPWAPLDPYDASKSTVRPFRKGRSYPVRGAAAKKLLARKNKKLEEDGVDGVDDPAFKERFLLGANRPQWSTWVWNELDERALEQKFKKKYCKAPCLMTSCDALWRLETKWKGLMRRSTASTTQSAQAILLQEQTEEEQEEMHAMTLESGLINDAYVMDPVTDDVNNDDHGGDDDDYDDVDDHAVDFGGDEDAWDSAPHRASMSLLDGATSRSNDAHDSEKGLSYEEICRQHLEEFMKGTEKYMRETDLTRQVNEWQDKLDPILKEQNSHPLFDIHHYGREILGHLESKKPKRKAPKRRKRPDDERSDEEQDGDETAPIPFGEIVSGLNQFEVCRMFLASLQLANNGNVHLVHGNTAAEQEAVPFEMQLLTTDDVYNSLQGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJF8</accession>
    <name>A0A8K1FJF8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000745</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJF8"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000006">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF25">
        <property type="entry name" value="DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="141"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="380"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="605"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1064" mass="119616" checksum="05001D6672F71C52" modified="2022-08-03" version="1">MADEELDLFSAFDAGETLTAEEKVAATSASKRKEAPAKSTEDDVPPSPKAKKQAQDDVEKISAKLSTDVKIVQGKYIDATPVDKSDDGTGVHVATGTTQKNLISFSVYPPDYEVQNVEGRSNANPAKTYPFTLDPFQQSAVDYIEAGESVLVSAHTSAGKTAVAEYAIAKSLRDKQRVIYTSPIKALSNQKYRDLEEEFGDVGLMTGDITINPSATCLIMTTEILRSMLYRGSEVMREVAWVIYDEIHYMRDKERGVVWEESIILLPHKVRFVFLSATIPNSKEFAAWICHIHHQPCHVVYTDYRPTPLQHYVFPAGGNGLHLVVDEKGKFREDNFQKAIATLTASATNDSEDLASYGSSTKKKKAKAGGASAKKKVGADVYRIVKLIMERQYDPVIVFSFSKRECESYALLMSKLDFNTEEEKQMVDQVFKNALDSLSDDDKTLPQVDSILPLLRRGIGIHHGGLLPILKEVIEIMFGEGLLKCLFATETFSMGLNMPAKTVVFTNCRKYDGKDFRWITSGEYIQMSGRAGRRSVDNRGIVIQMLSEQMEPQVAKGILYGQADPLFSAFHLGYNMLLNLMRVEDADPEYMIKQSFHQFQNEQAAPALEDALERAREERDQIVIKNEEEVAEYYYLSKSLVKLKEEFLAVRNKPEHAVRFLNAGRLVKVYTRPNDGNEKKWDWGVIVNFTTKNAADSTSPTPDHVVHVLLNCKSSANGKTNEAPNETPEPAPIGTMGLASSTTAEMKICPVPLEMLDQLSSLRVYIPKDLRTLDSRQAVGKSVKEVLKRFPQGVPLLDPIEDMDIQDESFGRVISRISEAEEKLKASAFHEAKDKDSRFALYYMKMESETKMRELERQIKESKSLVLRDDLRRRRRVLRRLEFVDKDMVIQRKGRTACEISTADELLVTEMIFNGQFNDLSVNETVALLSCLINQEKAKEGQKPPLADSLEAPIRQMRETARRIAKVMHDAKITIDAEEYAESFNTSLVDVVIAWCEGAKFSQICKMTDAFEGSIIRCLRRLEEVLRQLTQAAHTIGDIELEKKFAAGGEKIKRDIVFAASLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJI2</accession>
    <name>A0A8K1FJI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor IIIC 90kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJI2"/>
    <dbReference type="OrthoDB" id="6021743at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044230">
        <property type="entry name" value="GTF3C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024761">
        <property type="entry name" value="TFIIIC_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024764">
        <property type="entry name" value="TFIIIC_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12657">
        <property type="entry name" value="TFIIIC_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12660">
        <property type="entry name" value="zf-TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="5">
        <location>
            <begin position="62"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="485"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC putative zinc-finger" evidence="6">
        <location>
            <begin position="827"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="923" mass="100713" checksum="B172C6C5CAB338D8" modified="2022-08-03" version="1">METETSEATSATSVEATGAPTASTRSPEEAEAPVVAASKWIEPNNTRERIAGSPLVPNGVQWAEDGRVAIVSEASIMISTFMSRELEMYIQNSPAISKSFVFVPESTATDRVPLSIPVFNEPTDSHLPSGSLTYFLLNEKDRHQYNPKELSLSKNDGKVFVSATWGPRGSGPNSSCALLALTSSSRLSLHFSSSFHLSWKEVAVFSENIFDYLETRQWTLKPSKEAKGTPATKPEAVSQPPKTSTPGKARKTATPGTGSSKKRKREAQTVATTPDADDVPTISMAQYTRRSALVSTLSVAWSPFVTNTEQHTTSLIAFSGRAITTVWGYDYPSFDVFAAAENAASASAASSPTSPSSRASANSLFLSSTPFVWLDTEKHGWVTTSVWQQTRREVGQVHSTLTLAMGTTEGNVLIASIPVMPRDMHVSEVPIDRVIVPPHSQPVYCLCLGSKSTFGNSKRNDLVVASGSRISVWNLNKKRGPQVSWKAHRGNVTGLGVDYFGNELFSCGIDGVIRLWNSQTGEELPFRLGGSAGASTNESTSRAQSDQSTKCPMFGLAVSPNSAQIATISIIPPAARPNRKSQADVSYSRVSCALEYLPSPYATKPETFIDSICQILTNSQDMSTLTDVVWFCHEDNASITSLNGSADMTLPNLLNKLKGVSPGPDGTGSRQPLYITLCEELEKRYYSSETPAETIPFFLQASYLIRSCVSPVENHVAIRDEAMQKIKRTLYIYWAERCLKELLASHSQVQNFADISETERISALLMADYLSVQRPMSETSERLVTTIYNRLGSKDNIDRWSTYLQERVPEAATPPPDLLPPTPPPRQSCFICDEPVPFGELELSCASGHVQDRCFLSFQVISSMDMWKCMGCGGSACEIDFSLGRSPFYLLESHSKKANSAPGGSTLQVVCRLCGNYCSFMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJT1</accession>
    <name>A0A8K1FJT1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Exonuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_004155</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJT1"/>
    <dbReference type="OrthoDB" id="26491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000002">
        <property type="entry name" value="Exonuclease 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF65">
        <property type="entry name" value="DNA DAMAGE-INDUCIBLE PROTEIN DIN7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="19">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="18">
        <location>
            <begin position="142"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="369"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="560"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="624"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW66390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="72023" checksum="61B43E20CAAA7CB3" modified="2022-08-03" version="1">MGISGLLPVLKSITVTKDLREYRGETLAIDGYCWLHRAIYSCSQELCLGQDTDKYGALYIVYFTDRVNALLQNGVTPYVVFDGGPLPMKKGTEEERRASRAKNRELGLKYYQQRNYAEARKCFVRAADVTPYMAHRVIQRLKAMNVQYVVAPYEADAQLTYLMKNGLADGVITEDSDCLPFGCSKVLFKMDRDGVAQEVRTDNLGKNKGMSFHMFSDDMFLEMCIFSGCDYLPSLPGIGLKKAYSLLKQHGSVSKMIRAVRLEGKTRVTSTYEAEFERAFLTFRHQRVYDPRTKKIVPLTPIPSELLEKDAAMEFLGPDLSDDIAQAIAEGDMDPITKDRFAPASTPSGTINSYPPAVHSQEAATYATSKSVAEVPAQRPTVRNLPSWASKKTPSPLKQQWQPPQRQAVKPVTPTSRTISHFFASKEKKMSPVDESHKSTQNEPSDCSSDLTYQSQDQTEVDVTRSISFSPMDEEVKAVPHVPVHTDKENQTPESVASAPTSISKPPGTENAFARMMRAGSAPSKNPLKRKATSFSSRVGRFQGGGVMRHHESALERIKKHAFGPVETRPLSQISKEPAIESDLDEPEDEPNTESNQSRDSASQCIVRSACLQERLVVKEERKALTTATSRPPTKDAFAQFRFVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK55</accession>
    <name>A0A8K1FK55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK55"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="8">
        <location>
            <begin position="852"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="135"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="391"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="549"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="817"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="915" mass="103463" checksum="E479EA52075AA8CB" modified="2022-08-03" version="1">MQRADGWRASTPSLRRAATLKQVVEAVAMPSRKSGALSWRAETTPRVHVRPATLDVFEKAKAELQIELPVVVEDKPEKTSRWNGISRLLSRITAAETEKSASEETTTTKTTAEASASTDFMSVVMKEVQRVRAMRARAEASSVGLQERLARTEEQLAQATQDVRQKTALVGSLEAKVSQLTDELRRLSSADVHVEIEELRTRKQELEDELAGLRQGNTGGAGVEELTRELEAARAREVELQTELSQKEALGAARDQQLRNLELLRNAKNAELDRLLLEKSDAMEQLTAALTARDDLMAQSEVLRDELDQEKQRSSTLEARLTELTSELEALSAELAETKTALSFQTALASRLQSENIGLTNQHAELVERVETLLRDVALSKEAEEESEAKVKSTMEVMEQIRAERDEAARRITELSQELERQKAHWSDLLEEQSDKLKAELATEQEARRIEVEQIQSESEAMTELAAQALFEKENEVEQLSARLNELEGKLRAEVAQHRMTKDTLEEKLWILRQESTQHIESLMAQLTGSKKQVSEHHDDMNMNVEALIQGLEAAIQHSEDLVAQLAEKDKELDEMHASRKALKSEVTELRDQLTAMESGLRLATDGVETYVTQAEEAEQRRRQAEEKLTRARMEMDAIHGQHKKQLELLRGEKDAELERVQSEKSSVTKQLVVANAARARAEGEMRGVKTAMERLLTEREEAAREVQSLKADAEREKTRLTEQLETQAKEYQVSLDTEKKAFRKELDRVENESKVKAKLALRAMQEKDAEIERMAKRLDELEAEVKTGESDSQQILEFAQLQANREMEARANAARIEALDQELAAARTRIQELQQEKAKHRQEVVALTQTQRRGDVNIEYLKNVMVQYMTLKGDSAQQARLVPLITNLLQLTPTEIKEIEKANRRGASWVSWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK56</accession>
    <name>A0A8K1FK56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK56"/>
    <dbReference type="OrthoDB" id="123282at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040893">
        <property type="entry name" value="RADX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14944">
        <property type="entry name" value="RPA-RELATED PROTEIN RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14944:SF2">
        <property type="entry name" value="RPA-RELATED PROTEIN RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17659">
        <property type="entry name" value="RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="746" mass="83133" checksum="ABC8BA0A7A8CED64" modified="2022-08-03" version="1">MAMEMPHGTSLTPQGVQRLRKDAERDEAVVVLQVLGVFRYILDPAAKRVLPADVMEHADRDLFDVVVSDGQMKMKCVLSPTLNGLVWKNGVPRLSLVDVSEWTVLKDTTESVHAVPSVCLLRKIAFRTSDVSDQIVHPAASPQPVDVLTDVQFVSKKHEREHTAIPLIGERLYYLSLLADDVPVELDPSPGLLDALTPTSNSRFEWNRRRRYCSDLFQHSDRVIHTIREANIMTGKRKRETDGKDASPPPPMIGIVHFKSKLTHLGVPSLDNPFPWMFYIVISDWDRSVEVAFFGSMVSANFLTIQEGDAIQLLDYIVDRSTPQMNGGKPKKLFFFPHGSHGVVSHVPAKFWKLLEISRVLPAPLERSADSNKSHLWIEPTFLTTLDLQDWDPPASEDQDGTMFFDFVGVVSYVGRVHRQRTPKSSNPIALEAFRWIKVIDRSSSSEMVVLLGVCSQPSLFESVKAGDSIMITKLKWLHGSSDQQWEYATTSVYSFIRLNEDIEFFSILDDVSVNNYFAKSTLKPSIKTLYSSTGTSALSTESWIEGVEVENHQPLHALPRDLMTFATTLNLDVLSLSEAVQLSEDMDALLHRHVLVNCALNGAKSTSGSQGDEISIELGEGDLHRSVRVRSNPLFRAAEPPRVLLSSDAWLFAHSLPPQAINSLVAMVERTQKTFDKSLSSGSRRRSSTSSSSSQPPVVSLAEVVKVLQEAVGKTSDLTFSLHVYKSVDGQVEMTVDSIFLDLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK71</accession>
    <name>A0A8K1FK71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZNF380 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK71"/>
    <dbReference type="OrthoDB" id="77607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059039">
        <property type="entry name" value="ZNF380_CC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23406">
        <property type="entry name" value="ZNF380_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZNF380 coiled-coil" evidence="2">
        <location>
            <begin position="12"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="165" mass="18732" checksum="0DD47AD1970162F7" modified="2022-08-03" version="1">MAGSSKDKASAVPAGFFDDALADAKARDVDVKQIAEKQLEQDWEQFQEFVAEVEQKEAVEEEKKQDESKERDAVETLENMAYVDRYRQVLEKAVKGATDEDAATAMNGKKRPAQDEQEEEEKDEELSPAQLIRTARASSKRRKQAEESDSDSDDFDPTNWRAKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKM9</accession>
    <name>A0A8K1FKM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKM9"/>
    <dbReference type="OrthoDB" id="72325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000107">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="455"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="761"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="391"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="146"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="922" mass="102910" checksum="F5D087B3B6C4B43A" modified="2022-08-03" version="1">MNGSRRRVFPLAEIQTTDVVTGSSSSWLLPPKSPLHGATRPTSRASSPPPASSFDRMLMLRNMNVTGGGTSLPPPRAMESNKPLGWSPPTSSVPEISAAQAHKERKQQEARRREEVRLMTLEDYTNTPEGEARRQRREEQMHMAEEELLTQQLMQLERQQRREERLRQQREEEARIRDAFLLKRKQEQEEQARIAKEKEAARKAALEAKMQALKEAADAQARAQYALKQQQLQEEARKEAELRQEAMENTWMQVEDVLGAALRQEWLVEEARRQQIEAEAREWQRFEEEEAARREEETRQRRAAQAEQYAQDRQRRMQLHQLQKERARMVNEKTQQHQQHEEETATAKETQPEAEPVVQKAEESNDAEQPPSEEPVLSPVEEVATLTEPSSLIATESEDSPSAESTVSSNAESEDTVPIEPIKPVVESEPEPTAPPPIVETVTLSTLATTPFSQVLSVHAGSPAAHAGLCADDLLLQFGGITSDSPKCLLAIAELVQSHVNQAIPIEVLRAVTSNPTDEYQRFELQLTPRKWKGKGLLGCQLSPFKWPPEAPESPPKPMDQPETTQEQHVELLVIHNVLNDSLAHRLGLQDGDMLSKCGDLSTPQELTDLPTVSAYIQTHWRAAKNALPLELHRWMPQEQSYTVVSVVIPSPEDSEASLGCSLTTYTQYYYGSSSSSACHECLYTSLASAMHAAAVGGHLECLSALWAWYNHETLEWKDEEGRSALFYACYAHQLDVVQFFLTQLGAEDATYDADTGADLYGDSPLHAAAASGATDVAVLLLESRFIRDVNLVNHAQLTPAHMAVDVNVLTALSDRFQADLVLIDNDGRMPLLYACLRQDVASVKFLCARQPELVDYADAHGDTALHLAAWHGFLDVVQALLPYLPSIALYTPNADGQTAYDLAQDDGVRQLLSESMALGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL20</accession>
    <name>A0A8K1FL20_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002333</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL20"/>
    <dbReference type="OrthoDB" id="252964at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="186"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="51744" checksum="CF2673F63B490ECF" modified="2022-08-03" version="1">MASKYAKPLQIPGDFPDVLRNFTREVLRLQGKVETKEQVYEFGVQHFQELLVKRDGAGAKNAASAAGHGGAQPQYMKASEEELYATLMGAFEQLDPEQTGVVTADGYKQVLAFFAEQFQLSAVEIKALSAEADENDQGQIAYAGFAPLASQAIAQLRASRPHRIQRAEIWSKKEVEVFLHGMMQDEIEGLLREIFQRADTEDNGSLSRIEFMDALRDADLGLTRREVNILMAEAPVDEQDPMRVVYADFVPICFQVLRDVFTHGVVELPNDQDGLTQYLIEVFVSGDSEATGLLPVMELTKLFRAADIGLTRLQIITLMAEAQEDKSGFVNYEKFAGHVAGMALVLASFDSQQTFATYLQKYRKTSEYYTILDMNQHSFEQTLSRALEALDESHRGLLNRQDVVEAIRNTFQDITQRQLRCLLALADVDEMGDVEYNLITHSAFQALQKLQEYDMMVMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLL2</accession>
    <name>A0A8K1FLL2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLL2"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF22">
        <property type="entry name" value="FUMARATE HYDRATASE CLASS II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="7">
        <location>
            <begin position="406"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="464" mass="49928" checksum="D1D63A4DAF77601B" modified="2022-08-03" version="1">MADSQQFRQEHDTMGVVNVPINALYTAQTQRAVENFPFGHPFQPRLLTSLAQLKKACATANNELGLLPEDMMDAIHDAANTIVQDFDTYKDQFPISIFQTGSGTSTNMNMNEVLATLATRKLEKKVHPNDHINMSQSSNDVIPTSISIAAYLEASENLLPAMEHLVAVIKKKASGLERVVVTGRTHLMDAMPITLAQELGGWASQIAKNIERVKSALLRVRLLAIGGTAVGTGVNAHPEFGKKVCKILSNQLHAPFEQNDNLFEALSAPDSIVELSSQLKVLATSLTKISNDLRWMNSGPIAGIGEIELPALQPGSSIMPGKINPVIPEAVTMVCAQVIGNDVTATIAGQSGSFQLNVMLPVLANSVLESLHLLSHACRLLADKAIAGFTVNEQRVAELVGRNPILVTALNPIVGYEMGAKIAKTAYKEGKSVKDVAMEFTQLSAEELDKHLDPYKLTAGGIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLS7</accession>
    <name>A0A8K1FLS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLS7"/>
    <dbReference type="OrthoDB" id="10365404at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437059" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37190" checksum="E505E85D87E4D63F" modified="2022-08-03" version="1">MTMASRVLHALVLCALCALAVVAAQVHHPRGHPFGDDRGLPRSMQLIQVPQAIEINGHRVLYEDLNHALSPTLKETFDITRDGLRVFVQFQFDQMLAAQPSAKPPTMGRIAIVHNVTKEEVFRMPMRTDSSSRSELRAELKWDAKTRDKLKKDCMRATCQAHVILTNRFIGRSTVIDLGHLRFYKRSSGKTGVKIETAPRLIDDAPKSSPWMDVDLSWSTVLHGFLVLGGVFIMLISSEAWRVHGLVQPDAAEPVASVRWLSVVFICTATYSVCCLGRLIGWLSFESIQYVALAALVVAIIALIMAGGPPVEEEDYDLLDAETQDASTEETKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLV3</accession>
    <name>A0A8K1FLV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_005676</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the activator 1 small subunits family. CTF18 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLV3"/>
    <dbReference type="OrthoDB" id="2195431at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053016">
        <property type="entry name" value="CTF18-RFC_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765:SF1">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="296"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="757"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="827"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="757"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="881" mass="98328" checksum="EF50487274174FCE" modified="2022-08-03" version="1">MAMADDDVYAYEQEFEEMDEWEAMHEHELEAAEEELRAMEAAEAAAAAKRPESRDEPDEPMDVEEEEPDHFAALDDKLAQTQERVRSVLERCAEALGESEDAMEVTEPAEDVVVHKQKTGFVDTTTANYLFSRPPIDVDSMSIVLPTGERKFLRKRSVFDATARSSSASAVSKSLIPITAMMEALEQRQIESAVKADARPATREHAESKTGQQSNVLWLDKYKPQRFIDLLSDERTNREVLGWIKQWDRFVFPNKKQSHPPVETATPSFGKPGQYGKNADASGAAAGVDTNDPRPREKIILLCGPPGAGKSTLASIVARHAGYNPIEVNASDDRTAGVLKNKIISAMEMQSIWGDRKPNCIILDEIDGAMNSGDGKSAIAAIQEIISAPLNSNKDAKNGKRTKSSQHPLTRPLICICNDQFASVLRPLRKLAKIFVLDPPNSQRLVTRLKFICRSEGLRSTTGVLASLCANGGNDVRYCVNALQFQSTQTKHITSTAVASGLIGQKDHSRGVFETMDMVFYKAKSKSSSKAAPIMDQIDEAAQSLGNFPLLINALDENLPKMMYNDPTMNKICDAFEWMGIADAWDLKARSEQQFAFMAYVPFAARAVHLVCCTSSRRRIEYPKSHAEAHKKHEQSTNILRALVENSLLQPSMRQSADVLVVDVVPWLLATLSPSIRHINPSLQTADEKVMIQRLIELMASLGLSFRPKYLPDGTEDYALEPAVNELVRFRHQDSGNASSMVLPLPVRKMITREVELEQMRKSENSERGPRGRRTKAPSDLNQDAAEGAQSKPTKASQQFVLPTLTEQQVADKLEIMRKRNPFAFAHREAKRKRDEALKELEQTEEAEDTLMTKKRPSVRYRYNEGYTSGIKTTVFMKDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM82</accession>
    <name>A0A8K1FM82_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM82"/>
    <dbReference type="OrthoDB" id="58761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="28561" checksum="8976D3916DCF5CC4" modified="2022-08-03" version="1">MDSMAASSGVCDALLAKLDEVMSFLQFAKIPGAEFRGVVTFFFRSSQASDGDKIVCVRTVDMRRGIRVFTTALSASDPFASEAAPVHVSLADFLYMYSGEASASEIAGMCMSGRVSVPWGAYGKLKAFAECFDFSTEKWDAYYAYQAASGAVAATSLPQCSKPCCHSTTKEEIDANWCLVSDASTRTVHTHANGQMEEWEIVSDCNLHVLTPERREQIDETFGAGQLDEWLRKLCRGENVQKVHMNVKNTFNDFISLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMB7</accession>
    <name>A0A8K1FMB7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphatidylcholine transfer protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">START domain-containing protein 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">StAR-related lipid transfer protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_003884</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Interacts with ACOT13/THEM2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMB7"/>
    <dbReference type="OrthoDB" id="78947at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.530.20:FF:000017">
        <property type="entry name" value="Phosphatidylcholine transfer protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000268">
        <property type="entry name" value="Thioredoxin domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="START" evidence="14">
        <location>
            <begin position="43"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="277"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00079049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW66119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="645" mass="74108" checksum="C08038D96230C17B" modified="2022-08-03" version="1">MEEGGTPAHRVATKRLQRHKLQHRSSDPQFTELDMLDAVDMGEHAAWAQLDEPLYADKDFEIYRPPPVRSALPVYYIKGWLPYSADALFNTITDIRYRSQWDKSVAEYRYVEKQKDSDVMYFAANLPWPFARRDYVYRRWTKYFSKQNSFVMICQTAHHAGAIEVKDAVRVETFSLRMSIRSTGTNSCDFYIEYEDDTNFCIPNYVVNWLLSAQVPGFMTNLRMACANYAGFAKHLDEDGALLIPFRPHEVRMMATAVTLVLLIHLVQKFSNTLANEKSVTPDHGTRGKVNHPPDQQERDTMSAPRAGKPVGPVNTVRFMQLALATTMILSIMYMWDFISVSVASTVSKSGFLSSTTGTTRSNFLGETRIVLQGFQEGYKFVNEYDVATQGPLYIFFVSDVDENGTYWCPDCQKAKKSVYDVFARAPRGSRLVEIRVGSSDYWNNQDNEFRQNELFYIDYIPSLVKYEGGGNSSFMLNEEYTLDYDLLEYMFNVPYPAAGAPKNNKIVTLDEASAVQEYVMNYDNSYPLYIFFVSGYHSFNGRLWCQYCDRANIAIMHYYNYTAPESAVMLRAVVSHSYKMWKKKKNPFKLPEFRQNVVSIRGVPYLGRVTKDAANKVVVQEFMPDFTAKKELIEFFSQPAPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMC4</accession>
    <name>A0A8K1FMC4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMC4"/>
    <dbReference type="OrthoDB" id="165008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="677" mass="76594" checksum="5D8137949CE9A7B1" modified="2022-08-03" version="1">MTSKGNKYRVKNNSKMAIGKILHLLHRAAICGIALRVVYLSFSATYGAFILLRGDRYDWGSRDNGAYAYPVVQQYAGTDSIRQSPLVLKALGGDTTPLVGKSLYLREDSASFTPCTTFIDELQAEIFSDEFMRSVYTAIEEGTGYYVPEFNNTVELIAPVVDCSMGETGESDTTGARFHFLARKMADHDQVLLVVVSLSNQQYNIPEQLETGAAGIASVQMIYSMRDTDVRNYFAVSIGYPTEPFGFRAYEFVEMSADGQWALQSIPSHSMELTKSLFTSFRVGFYIKGETEQSSIDNMIWTISTNAQEVIEQWHWTSKAVLHDSWAWVHGIQFLIGTRLFASLFVLAIATYQNFRTGKMWIGDAFVSLSTSQLINGFAVLFSWFMNEFWALHEYSFHMAYNLVDVYDLEFYEAPMYADLFTIYLSACGIIGTLFRERIDPFLALICFEIGYTYRINLVDLVPSIRDQIVAHATEFYRRGDIRPYADQGSISPMSLWLSHPIGKKNYSFLISCLAPMFFTLIVIILYVIGRKMYRRFNPSAIKNQQNTSGTARRASTEDMMLAQKRVLTLFEVATGAELENRFGLVADYESCRFIKGMKFASADGIYSNGFVIANKKFLVQASDFWTILLIKTVRARVANVYVYEVNGSTVQPRARLLYAHTMTMVDLVNLNVSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMI2</accession>
    <name>A0A8K1FMI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001546</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMI2"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000044">
        <property type="entry name" value="Mannose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="10">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="11">
        <location>
            <begin position="176"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="410" mass="45714" checksum="1D140640BEB4CC8E" modified="2022-08-03" version="1">MEELQSVVQNYAWGKRGRASFVAQLKEGASAAYDVQETQTYAELWMGTHPNGPARILRDGKAEELLSEWLKAHPTATTKTKDGELPFLFKVLSVEKALSIQAHPDQKLAKTLHAKFPDIYKDANHKPEMTIALTRFEALCQFRPIDEIVAHLLTVPELRLLVDSDAMNLLILRRDQASLREFFRSFIHAEHQTIATQIASIKRRLGDRPAHVLQPVESLVLRLIAEYSDDIGCFCPFLMNYITLQPGEAVFLGANEPHAYLSGDCVECMACSDNVVRAGLTPKFIDKATLYEMLTYLPATPAILHGERIDDVARIYSPPVPEFEVEALNITPGKSYRLSQRTGPSLLLITSGNGVARHRGKKSREFKVTKGQVYLIAANEAVEIVTASDAKGSLSAFRAFPNERVSRRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FML9</accession>
    <name>A0A8K1FML9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenylate kinase active site lid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FML9"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001380">
        <property type="entry name" value="PRK00279.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011100">
        <property type="entry name" value="PRK14527.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="5">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="26719" checksum="1C7266FDEAF7512D" modified="2022-08-03" version="1">MAPSLAAVPTNLLLAELQKRIECATKKERRTIFIGPPGCGKGTQSPIVKDEYCLCHLATGDILRAAVRDGTEMGKKAKAVMESGGLVSDEIVIGIIKEAIKEPECRRGFILDGFPRTVVQAQKLDEMLALENTQVDKVINFDIPDSVLVERIAGRRVHLASGRSYHVKFNPPQVEGKDDITGEPLIQRKDDDVSKISTRLNAFHKQTQPVIDFYRKQGKLVDVDANSGMKNVSAEIRKNLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPL5</accession>
    <name>A0A8K1FPL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005957</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RPGRIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2133912at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021656">
        <property type="entry name" value="C2-C2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031139">
        <property type="entry name" value="RPGRIP1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240">
        <property type="entry name" value="RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240:SF5">
        <property type="entry name" value="RPGRIP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11618">
        <property type="entry name" value="C2-C2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="811"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="1168"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="1511"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="1809"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="2248"/>
            <end position="2283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1211"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="244"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="568"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1296"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1221"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1246"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1263"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2564" mass="290762" checksum="25A38B020B40EF0C" modified="2022-08-03" version="1">MATDFEEKYLQLRDENTALKKKKNEQEATIKRMYTKLAMIEEAMKKKRIADDSDNQEDPDTGGKSALNGAIPARRDLETERFVQALKAENTQLRKKTQVLLEKNRQLEEKMRQHQLKYHSNPKAMSASTTNASMSKRSVATAAKVHNAVMSKRSEGFAGESLERQVDHARKNHRDHLSGDLEMALKNRLVVAEKQLVRLQQENEQLRVQVDQKKPRTTDHAAGNNIHSDDEDGDTRKTASDLDVEHLKRELRDRQAQISILNARYDNLEANTAAEREIQEKTLDQLEHMNRQVHKLRTQLQDANLENEELQVRIAKASEHEREISLLREQNRKLEDRMTSLCESPFINDAFQRKERIDKMFDLEKQNQQLKATNTHMTEEHQKLQTIVKELQSNIRLMKQAKDMVEQDMDKLRQQLVEERNARQLALSSIPFVSAQPTPRSSSPVRETPRTTTISIQPERRDASSSPLKTDQPPSFANFNFRPTGAEPIVTRKFTDNILMGPVPEAPSGDHDGSSKHLRNRVHVLQIAHLKAMQELERCEKMLHAQTNINRELALEVEELTTKKVSSTEKLQKRMKELELIAEERQQRIQQLEAQIRQLKYARERLLHEQNANNNERDDSSSSDGDDSEVASISESLVFAARDLAPGEQLLEIWILNAHFDRSVITSTSSTFLLCDFYDFESQSTPLLIGNLPDYNFSATFKVLVDAFFLRYVASEMLVFELHQAVQGDFRLIGRASLPLAGLLKSKGAIKESALPVKLVYNDGNDKIIGTINVVLRLAAPISEIWKLHLRSYPQDVQLLRHPKFRSHDLNDASLLDDIGENNQPRRVNELQITVFACRGLRSYGKKKSNQVSTTPSAYVHYQILGFPDMFTNIVPGSSRPEFDLSTSKQFFAVEVDACLLRFFSKFQLRFTVFDDQLELNDDETTGDGVISQCGILLDDLVKGESIRGWFELRDRNDQPAGEISVLIEWKDAFQVAQLYSSSRVNGGRSQMVDLHSLDYDQQHAVMAMFSPQMDGRVNYRQFVRYVLPSAALELLAAKIKERLEYAIDTEQIQNARDIFLKEGTRSDPLTLVQVPAVQSALAKFGVFLSNDEVETLVHEFRDVQASVTKSTIVDTNSSSRQVMLHYLLLHINPRLSCAERLLLHKIRQTVRAYLRPEKNSKPLALPFDKYDPAQTGFVSRAEFKRCLLILGFELLDIDNAYKDLVERETQGNTVQLSARGSKDDAAKEKEECVDLDESTLKEATIPSTAKTNPQGALIATQDRSKSTQEPTEKKVRPPVMVSDTKTTDSKRLTAVEEFERRKQIFRERIKEIASAGSRSVVYEQIDKKAMEQRKEIEAQHDQSNVQKRITQLHVPQRVHDDAARTLQRQFRHYRTQKVGASRVREEQASGLLAIDLQLQKIFKTWTSGELEALEKDLIRMVETEIPEAKKRKSISRKQFGFVLSKIPRMALEPTLLRQLMDAFSMVPSAPSSDIAYRPLIHFICSVLSTPKRAEQKQLPLMQSLNSITVDVSVVLQTFMSVGDMNGSGRISFYRFREALQRLGIQLAAKDLRVLMVLLDHNGIDLLYHGLLVLLRESEGVTQLRQVVDRCARCGVGRIRDQLLTKVHSDDGYITREELHSVLMQENTDATRFEPRDSHVLYGMVRNLTQKAAPEASSMPSNKISMETLVLMLEKLVQSDDVTDEMLNAYDLKQLQSLATNYRKLLRPAFGDVVAEFERFDWRELGVVSLLEFVAVLPRIGFRLFTDLQIKQVAKAFGTKLKGTFGINYRQFLDWCTPGQNLDIEEIETKLRRFAAVQAERTDSKQVTQRLGKWRETFAALDRFSSGYITRVDFAKVCTEVLTLSVTGDELRLLLFSYDQQLEDKVDYKAFVQLNWKETSKATVRKQVQFDDSRREDLSKLVARVRQLLLNNRVTIDMVKESLEDTGAGPTSPFVEQSQFLVLMKRRGVSLTPDEVQMIFAVYGSKEDRTQLDLVQFAQQVLGLKETTRTKINKPVISKEDDERLTSAVASALKFSRKDMERAMAQLEEFCVVYSFGEIVPHKLWAHMERSGFSALLSKKGAGLLIQKYTRVVAEDDKASDDEGEGRGVVSLKEAHDYLKAALLNAPAVGPPDPAPSGPAGALQAVAQILEACEANSADLRGSFEDIDSSYTGFVKALELKTLLTNHGIVSCVASGTSPESVIGALVRQFRSADARDAVSYVVMLNQATSLQSPPPAWLVDLSENLRGRIRKKAGFSGRIDLDQDIAQLSHRLDSAFAHFDQARKGFLNQDQVKIGLQALKYSLSDDQVNAFISKIGVFCHQSGSGGVSRMEFDAFVVDPFADRLLCRLAHLLNKPSDDQSGLPRIAFLSRLFMERDQHTQSGVLPLFAGLDAVETAIGCSISHRDQCRLQILFDVHRNGDFAYKLFLKVISQWRSAAGVPVTEIKPPIQRDSQNPQTSQTQLSCTREALLRSLYNQLSSLDFESQIDLLEEYLRRKDWRHTGVVKLKHFMHILDEIHLSLSKDAIQSLAHYFAAQQGGLDSPRDTTSSCISYLVLIKAIAALDEASKNDEPKPRARRSSRKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPW0</accession>
    <name>A0A8K1FPW0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPW0"/>
    <dbReference type="OrthoDB" id="68488at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467985" evidence="2">
        <location>
            <begin position="17"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="36796" checksum="7862B2186C362343" modified="2022-08-03" version="1">MRNIWVLALFWKVVLSLHSRWMAGRARRWHPKAGILAIRAVFISTASSLTIFSFLRALRFRETNILFFQMLPRHARLNDESLAPAYVSDSEFGRMIDAKTVILASLVVFSGVVVLQLAVKLITHRTPNFAFCRSFYIPLSAGALYPKSMHGIFWYIRCKQPYEQEQPLVGRRSSWERVKTSFASLIAPSKPPRRPPRGCSGCDSPLTMLHWRNIQGCVRHERMFSVESRSTELWSVIRLVNIALLSDPWQLVQLYGVGRPVYLYCLIAPQWTLGKHEVDSMRLVLLPRRLRTPCQHGDIGHLDLVAVIDSSVVPWTALVDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQG4</accession>
    <name>A0A8K1FQG4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007594</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="712"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="765"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="843"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="867"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="950"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="90"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="411"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="726"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1046"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="672"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="672"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW67922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1295" mass="143077" checksum="C09C38EB6ACEDFEF" modified="2022-08-03" version="1">MVTYATFDASGDPGDATHPHAQASWPSTLFLSWATPLLALGNKKRLDADDIWPLQHAHQASVVATTFARDFKTSKSVVQAFFRSFGWRFVLTGVALAIATLGALVGPLVLNQVVSALTTGVYDVDELVTWVLVLFATQVVQALVENYANFDSRVIAMQLTAALKHLVFNKAMNLSAASRRETKVADITSMCTTDTRAIAEASLQIHQAWLTPLQVGVASVLLFRLLGVASLAGTSIILLSIGVNRFITAHVFRLYSAFMKSKDARLQAVMETFKAMSIVKQNAWEDRFLKRIRDTRAEEVANIWGFLKFNAYSAVLLWGVPIFVSIATFSVYVGVLHEELTPAKAFTSIALFQFIQLPLRNFTYIITSLVKAKVAEERIHRFLEMPEIDADNVHSIQHTDANQFIKQNVIVAIQNATFAWDNDTPTLKNVNLNVHAGDFLVIHGPVGCGKSSLCAALLGDMNKISGSVYVGGSVAYCSQQAWIQHMTVRDNILFGRPYDRKKYEKVLEACALTKDLQSLPAGDRTEIGERGVNLSGGQKARVALARACYSDASVFILDAPLSAVDAIVQNEIFEKCLLGLLRHRTIILVTHNPEIIASEHVTSAVTVNDKGELLETRDLNNQSRPQYESALTPLAQLAYTQPSYEDAQIADEKVAHTTDFQKVLGPGTRLLNDSPTSFSRSANFSKSDKPSESQALVRDEVRHAGRVGAHVFVSYYHALGGFPVVALVLAAQFLWQGFQVSSDLWLSAWSSQSSHDDQVSIGYRISVYTLLGLASALMVVIRTLAISWCGINAAKHLFDRMTHALMYAPMKFFDSNPIGRIITRYSSDVTDLDMQIPIAIRGFLVNLVVFLFTIGTTAVMIQWRSIFLVPVAVVYIQVARYYLEPAREIERVQKTAEAPVLSHLSESVEGCAVIRAFGTHHVHRFQVTNDAKLDAANKITFARICVSRWFMLRIQLLGSLLGLVVSYSLVLLHDELSAGIVGLAFSYALKFSNSMERIVGTWSSVETIMVSHERIEQYSAIEQEAPRKVPTFDPPASTTWPSAGAIRFENVSFRYKDADQLVLKNLSFFIQGGEKIGIVGRTGAGKSSLTMALFRINELAGGSVLIDGVDVGKIGLKTLREKLSIIPQNPVLFKGPLRRYLDPFGEYSDDALWSALRRVGLIDRITSEDDKLECMVEENGENFSVGERQMLCMCRALLRESRIVIFDEATAAIDHETDQKLQHVIREAFVGSTVLTIAHRLDTILEADRILVLDGGEVVSFGPPSELVSAGSGHFYDLMREGGYLDKFLSHKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS54</accession>
    <name>A0A8K1FS54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS54"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000556">
        <property type="entry name" value="Probable protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="25903" checksum="A85F9D3641855BDC" modified="2022-08-03" version="1">MSFWPCSSSSNEGLVQNLLRTGAIQSPEVFEAMKKVDRAKYMGMNSPQSEPISPLRAYCDAPHPIGYNQTISAPHMHAHALELGWAAVKDVAHPRILDVGAGSGYLTACFGRLIEDKPGSVFGLELVSPLVQFARDNLQHADGDLMEKGVVSIHHGNGWDGLPNDGPFHYIHVGAAAETPPQGLMEQLANGGRLVVPVDEDRGGQMLVEITRNGNVFSQRKLMSVCYVPLVRPRKHSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTN3</accession>
    <name>A0A8K1FTN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001919</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTN3"/>
    <dbReference type="OrthoDB" id="162896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457040" description="Protein kinase domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="407"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="692" mass="75401" checksum="C829F84CCD4B45B5" modified="2022-08-03" version="1">MTRLLVALAAGMASAASAATCPKSGIEAPDKVALAVDPSQSDNVALVVTSECEESEIQATAADNVGEFRITANDMGIKAVESYPAVQSLVLQDNVVASFKAVGTSLKEVDLTNNQLASLEEIAFPSTVLRIFLDFNPIKSFSASDLPEGLQKLYFRKASLSSLAKYSFPDNLQELYLTGNQNLVSLKGLVLPDSLRLLECSDCGVKEVVGVVFPQSLSKIIITGETISSFVVRESDVAVLKKMQLQMDVGTISSCSSVDAKVTPITSSINACVMDDTSFAIMYPITPTSAPTTIPPPTSSPPNTTAPTASPVNQTGGGDSSSTTTIIAFVLVVVAVLIIATIGLFCYRRRKNRRRPPSTNNLTNTNTKSVWEGMGAFNSNSVNSGFLMNDVRNDTNLIPYRLPHDAIKIVAEIATGGFGIVYQASLYGQTVVVKQVAPAKANSPEILSRFMDEIRLYARLDHPKIVKFMGLSWTNLLDLSLVMEFMPHGDLNSVLKMNHRLSRGRSLFSWFDEQSEPRCKSLLVQDVAEALVYLHSFIPPIIHRDLKAKNILLSENFEAKLTDFGISRETAEETMTGGMGTTAWIAPEVLDGERYSEKADIYSFGILMCELDVCGHPYHRNKTGVDSMSDAKIAYLVVTEGLRPLLDPECPQAIEQLIMSCIDHDPSKRPTALEVHYTIRKIRDATQEWGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C289</accession>
    <name>A0A8K1C289_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine amidotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C289"/>
    <dbReference type="OrthoDB" id="59438at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="111"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="316" mass="35155" checksum="8B1A68FC29233A86" modified="2022-08-03" version="1">MLLRALRASTRSSLASIASTRGLATSASPLSVLVIDGYSKEGREDLAAGGASTAGKLYDTLLTKCTPHGNIKCEIVYPADEEFTTPDLTKYHAVAWTGCSLTIYETEDVRVAKQIEFARKVFEYGLPQYGSCWAAQIAVAAANGVCGKNPRGREMGLSRKISLTPEGRAHPMYEGKPTVFDAFTSHNDEITHIRPGGLHLAGNDFTSVQAVAVRHLNGEFWGVQYHPEYDLHELARLTYCRRQKLIDLGFFQDMKSADQYVEDLENLHIDPNRYDIAWRLGIDADVMDETIRHCETRNFIKHLALPYKASLDNLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C338</accession>
    <name>A0A8K1C338_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">P-type ATPase A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010445</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114962at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469072" description="P-type ATPase A domain-containing protein" evidence="13">
        <location>
            <begin position="26"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="676"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1187"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1220"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1304"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1359"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="14">
        <location>
            <begin position="544"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="236"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW55563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1399" mass="155998" checksum="89EC8697E995FC5D" modified="2022-08-03" version="1">MKQSLRLSLAVAAVTALAHLDSVHAKTANPLDFPACPESHSPEYYCCEYSDTVKHVYTKYNLPTGGSFEDVFRDGWKMARQVNYPYHKFTPDTPKYYYDQPETICRMRTVVVNSKTGEIKQELQCANQNSSLVEDSQDATVFWTYAENPRNNNASFPVGAKCYSLMTSNGKVDAKEKALCVSAASTVTPKFTSYTEVELVVIYVVYLACFAAIFAWSLYKTAMKNKLKATADKSKPLLAHRGGPSTPNKNHGDNKHTQVRFSDSDNQEDDDGILQTGYSRSIFGTIVFAYFIIVTIGLCALLLVIVLDYYGLLPEVLFDPSGANVMVFFIVWLITTVWYAATVFATDSLINFFRVETDLSSCEYVDMLKRDDTELLLMDRSGVSDLIARIEKVFVSENHIKGFQKTVPVEHINELRVVEFQHVRYIYDMTAARFIPGSVKMGETYASILNEASGLTDAEAQIRYNMVGPNAVSVEMPSMAKSLAHEFFTLFYIYQVMCYFVWYYFDYYTLAIVMTCVVAISAVINIYTKRRMQASVVEMTSYTTEVNVYRDNAWRVIQSPDVVPGDLVRVSENWVLPCDMVIVRGSTVCDESMLTGESMPVQKFPVPENSHTVYEAMGSGKKHTLFAGTRVLSSGRNEEIHAVVQTTGPNTSKGELIQSILFPLPMRFKYDEHLKMLIAGLLVFGVIACGLTVYFLTSNGKLSNKMSAFCYCIFVISTVVSPLLPVVITVGQVNASQRLEKVGVFCLNSQRITLCGKVRVFCFDKTGTLTKQGLDFLGLRPVQSTAFTPLVTDVQSSSDISAIAQYALATCHSVGSLDGRLVGNEVEVKMLTASGWQLVEREGEQPYVKSPTDAGLELEFVKRFDFDHHRMSMSVVVRDHKTNKHYVFCKGSYERMQQLSLTESVPADYQKVADQLAKDGCYVLGISFRELPAEWTDADVQALVADREAVDQELSLLGLVLFRNELKPDTADAIAQLKAGDTRVVMITGDNAMCGCYIARQSGMISETSRVILGDVVADELVWRDVDQETQFNLTEIKSMVDGENDVELAVTGRAFDHLVASDEIKELLLKIRIYSRMTPNGKIQCVQLHMETGAVTGMCGDGGNDCGALRIAHVGVALSDADASVVSPFTSRSKTITSVVDLCREGRCSVATSFASVKMLVMYGIIASTLRLFQYYNGVIMSEWCYIIADGFTMVGLSYFITLSRPLPTLGDQRPTSSLIGPTTLVSILGQELINVIFLFIGINLLTGQDWYCPFTPDNIDLAKWWLLSDNAMATCLFYSTVTQQQLAGWVFSFGSRYRLPIWRNYGLIAFMIVLIAIDLYLILGEPSAVTDLFRIASSTNVVVLPYVPLPQSFRAKYLGVLIGDVIAVILFEYIVVLGPVRNYFRNKYHKDHLPMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3B3</accession>
    <name>A0A8K1C3B3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010521</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3B3"/>
    <dbReference type="OrthoDB" id="10051896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474524" description="Peptidase S1 domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="10">
        <location>
            <begin position="55"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="10">
        <location>
            <begin position="367"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="596" mass="61824" checksum="58433D3E2D958E75" modified="2022-08-03" version="1">MKFAAIATAGALAVATASASDALSYTQYLASTELQAKLLHDANVTDSGSKIKPLIVGGSEVPVGQKLWTAGLRETATGSDFCGGTLITPKHVLTAAHCYGTIKYVAVGTHYLSGSTDGERIKVSKQTKHPQNNANTMTYDFLLLELATESKQTPIKLKIAEPAVGVTATVNGWGVTTEDGSQPSGMRQVDVPIVSDSACAKVLDIVPATNICAGGKKGKDSCQGDSGGPLTVKSGSDDVLVGVVSWGNGCGLAGYPDIDGCVSLFCFLCIVDLLHCAPYCCAYAICEGQIAEKSLGHSQIFRLQARSSSRSFIMKFAAIVSAGALAVATASAKESLSFPEYLVKSQIATFLANHPEPTEGNKFQPLIVGGTEVPVGQKLWTAGLRETAAGESFCGGSLITPKHVLTAAHCYGTIAYVSVGTHYIGGSKDGERIKVSKQTIHPKNNADTMSNDFLILELASESKVAPIKLKTTEPAVGVTATVNGWGALKENGNSPDGMRQVDVPVVSDETCAKKLDIIPENNICAGGKKNKDSCQGDSGGPLTVQVSSEDVLVGVVSWGDGCGMAGYPGVYASVPSAKAWIDATIGASGYNATWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3F8</accession>
    <name>A0A8K1C3F8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010633</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3F8"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="209"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="425"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="67961" checksum="7A3B36F21598AFC5" modified="2022-08-03" version="1">MRLICAKCALAGPEAATDASPLAPTCATCEMPLTPPSVFDCARLGLLPELQELIHADLTFDINALEATTNATLLHHAAINSKMRVLEYLVRAFKDTIEIDALGGELQTTPLFWATYHNHIYAVELLLREGADASFTDDAGFCPFLVAIQRCFPILAAYLVAKGTDIDTCVKDELQRSALMLLCQPQRFHLDSFRMVLSLQASVDVQDADGNTALHHAVLNDLGIAVRMLLDNNASPLIENRDGKTPFDLARELLRERSMARHLLEEDRQLQRLSQLTFLRKRWLEDNVYKVSFLVPWIVIPAFAWILATTNGPVLIVLKETLLLMLSMGALKILQRGSYGDKRKAAALMFGINVASIFWLGYALPLFITPEISFALQASIYASIFLILAFLFLTAITDSGTVFTTYQEKLYNIRTLVESKSPSATKLCLTCLHRRPLRAKHCAELNACIAKFDHYCPFVMNAVGAENHHYFVGFLVFAVAGISMALMVCWRYLIAQPDIAWGDGISAFIWSFFHYHPTLVSVMALALLHDLWIGYLLFFHLFLVLASLTTNEFVKHENIDRVYSRGIVENAIDFFRLPGEQRVDWRTMYRHEDFTAVINKAKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Y6</accession>
    <name>A0A8K1C3Y6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Y6"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Apple" evidence="6">
        <location>
            <begin position="521"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="431"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="667" mass="72239" checksum="3A4BDC9329892252" modified="2022-08-03" version="1">MTSEPVISLEAWKKTAYYAEAYAMHFLPEVSYKYTTASSSDGGKFTMATNEEGGSAAAEEKKRFDQALEVIEVLKHQHPYATFSMNTPFALMTEAEFHDYVTQHNIHPAIEAAKNASKESGSRKGGPMTRAVAPGERVDWQEKGCVSDIKDQARCGACWAFSATAAMESGVCVETNFKSLPNLADQQLISCDDKGESRGCAGGYASYTLPRAEMARCVRWINMPLHRAMRLCLVQKDPEQMEDQVRKRPVSVFLYSGSRAFQFYSGGILTGENCDKSGPHSALAVGLGEENGVPYWRLKNQWGTKWGEAGYLRIQRRYSGDDEGACGVESFATWPTFKEKLVVDAPNPNFQPTSAPEPSSQELTPEPTPPPPPARTPQSTTPTPEPSTTAPMPSPEPSTTPSPEPTPSPTSKQPATPKPANEAPPIDQRKPTSTPAASQEGSNSQQCGRLDGGVDYLGNDIKNEPASSVDECCALCHGTPGCNAFTFTNWSGGRCWLKSRAGVIVSLPGAVSSSLHDISKCTHQCSPQEIGYDYPGNAVESKSAQSADQCCDLCQQNTNCHAYTWAGDNGGICYLKSRKEANVELKSSRDITSAVVYKCRNLQPNVDFQGQDLTHEPARSPEECCAICKQTKGCAAFSWSDCKAGTCWLKSDSTNAIPTHGVVFAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4C1</accession>
    <name>A0A8K1C4C1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008848</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DZIP C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4C1"/>
    <dbReference type="OrthoDB" id="515971at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032714">
        <property type="entry name" value="DZIP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051241">
        <property type="entry name" value="DZIP_RILPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21502:SF3">
        <property type="entry name" value="CILIUM ASSEMBLY PROTEIN DZIP1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21502">
        <property type="entry name" value="ZINC FINGER PROTEIN DZIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13815">
        <property type="entry name" value="Dzip-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="294"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="449"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="558"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1051"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="198"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="366"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1051"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1111"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1176"/>
            <end position="1194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1223" mass="138852" checksum="125B147C70CE12C9" modified="2022-08-03" version="1">MSGYDEYEGVFGPLSAWNADNASVSTSSRRRGARSRRFPGEEDHASVFYGQVRGFRRKSSSRAVLGSNEFARREKYLTERRSKRRLASIGDEDGEMAAEQERPTQDANQIWLPPKNFSFRQRAGKLDTRTIARLDLQKIIATTDIDAIQRHLENLAFSDVTLEDVQQYSDAYFLKLFQIAQLTLEYLMNVQDSLVSHCDNLETQCEGLLDESLALEQENERHESEITALKKEIRQKQSTLATFEVMLLNASAAKRVQGQRAKSALASDENDPLVLNILGETPPTEEEGVISSPVDCVICGKKFVGPEYLVRHQRRKHRSEEQTKQKKKKPARRSSSSSESDASASDESQRKRKKRTPKTLPFPVEVTQALQERNDLAKQLVELQAQLQLERERRAQESKQAEQQQAQLATQVTGYMSKLQDMLVAIEQKQEQSKHEVMRYTQETIEKLHTEQAKARPEPPKKSNAGQIEDDDESAMTKSAKKATKETSGDKLEQIMKAFLRAQAEKQHAIDTLEQENRKLWSKQQRLKRRQRHEEPTSTLMTMAALDAQRYGIDAGVLSDPMNKPPAEITKPPASLEDKPVQTDEDRAEPPKPKPILTSIEIQTDALPVPVIQAPQKEEKPRLESKPESKLQTPLPAQLPARQAKPAAKPVAEEIKPEIKPAEPEVVPIPEPKLPEPKQENKFQHAAKVIGKVARGFLIRRELSNPNNWLIVVSSESLQQALSPSELVHFTKRQDSGLRDVEVEVEAAMTANELRLAIADALGQEEADDVDDSFVVPFDYHRVLLHHKLTKEELKGDRRIHPMRDLIEIEIIPFFDAAEAHVAGVLEQHDYQSSQIQDIRCASMTLEETTETVSHNADSNLRGIIRFQAYVRRFLARRTVQMMQVDRIVEARLVKMRAASHDDNTSLVTALIERRMTRAASVLSVRMRRASQEEDEQAIFSQTQIIHSRLADVVQQKIGLDTRTKSAKWSKGQLSAEEYEKHVSTLQEQRTQLPPAVQDRIQVLLERVEDMARDEYDPEQAKQEEDQYHAANRIQRAVQVTIARNRLHRLLDKSPTREQSVESLSREERDSPAVSDQNELIDEDNEKRDVELDDEEMKGDMVVEEAEEDDEIKRLADAYELDGTIRLDSKTHEPANSEQPKEETKPSQAVRPAPTEEKPSARPSVEIAPRPGTPPPDRDDLVGRSPRPKTEDVNRVISPFSKTPLLSRRAAVTRRGSGYDNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4S6</accession>
    <name>A0A8K1C4S6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4S6"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="16990" checksum="F6836024DA8C25B9" modified="2022-08-03" version="1">MDALLENQKILTKSGDHVSIAEALGQKKVVGLYFSGHYCPPCRKFTPLLAQVYEEIKEEHDDFEIIFVSSDKEIEKYDEYYKEMPWLALPWAESRDLKAALCEKFGIKFIPTLIFFNENGEVVEREGRTFIEKNAHDIDAVLSALRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4T9</accession>
    <name>A0A8K1C4T9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c peroxidase, mitochondrial</fullName>
            <ecNumber evidence="10">1.11.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_006566</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4T9"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="131"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="36856" checksum="83785C9272DFEF84" modified="2022-08-03" version="1">MFRRAALRAMKQASAASATRTFASAGAKQTKTKSGAVALAVAGVATVGAFAIADVAQAREKHVDIDQIKKEIVEIFDGNNYMGPTLVRLAWHSAGTYSKKDGSGGSTGGTIRFDPEINHGGNAGLHLAVKALEKVKKNHPEISYADLYVLAGVAMIEEMGGPSVPFRLGRPDATSGKECTPDDRLPNADMGAKDKNSNHMRDVFHRMGFNDREIVALLGAHAIGRCYPDRSGYSGPWTNAEWTFSNEFFRLLLETKWTPKKWNGPKQFEDPSGNLMMLPMDLVLVEDPIFRKYVELYAKDEELFFKDFSDAFLKLTENGVKFPEEKRKGWWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5E4</accession>
    <name>A0A8K1C5E4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5E4"/>
    <dbReference type="OrthoDB" id="167057at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="35991" checksum="3A2860C1B34D2DF9" modified="2022-08-03" version="1">MPHELSLSPPATKRVRRESQHQEGDAKAPRRRKPRLVWRTRDSERSKEYNLTLDVNNVKQEIHDLQMMRDLLFARQLNRPDTNDGSCVKVVRQYYHALRYGYQDSKFDMLAFFRSVVDEYVRLGRFVGIKQLIEMSQRYKMICSPMHMTFKHAEVIPQDTTPGSSPEVVVVATFSYAGTVTELGAQRVFPSLLTNPDLMKRLIGQQVGGMGKAHFIVDPTTLRIVGYVFDLNLPAAFLRLLKNVKKVARVLDGSRFTPEYYIGEVSNPVQEPLNDEIASKLPLPEADPATTAWKMSMNTLLSSEDDDQEPEQETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6C1</accession>
    <name>A0A8K1C6C1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6C1"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF35">
        <property type="entry name" value="ACTIVATOR OF HSP90 ATPASE AHSA1-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="58"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="194" mass="21728" checksum="BB6A49B585BA4E7D" modified="2022-08-03" version="1">MASDEEEPKKMHSGYHGWMKTIPKTGHDFTPVRIDPTAAATASQGEGSAWNAAGTWEERDKSEWARDRLKYHILTSFTFSNDALDVKITASAIDKCEGDAKVVFSRGKKRCGYDIFLKFEWLATHAAGDADEAETASGYVELHDFDDTSGEDYEVHVTVQGSSQHAKNAKRAVEQWETGLRKILATWKEELLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6P1</accession>
    <name>A0A8K1C6P1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002949</name>
        <name evidence="2" type="ORF">Poli38472_002952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6P1"/>
    <dbReference type="OrthoDB" id="25576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899">
        <property type="entry name" value="PAPAIN FAMILY CYSTEINE PROTEASE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35899:SF1">
        <property type="entry name" value="PEPTIDASE C1A PAPAIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="100" mass="11430" checksum="E2D5AAACAA164F9C" modified="2022-08-03" version="1">MCPNSYRPDNWYQCGQDGEVIHARSNSGARVPLPLTRRENVTGIEECLSEETKLYAETNIQPLHLECTDEAYCKTGAEYTYFARNATAWGDRTQVMCFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Z4</accession>
    <name>A0A8K1C6Z4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003102</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Z4"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="102"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="170" mass="17098" checksum="FB05FED3E456CE20" modified="2022-08-03" version="1">MLAQLVANVCPSSASFFGFMGVASALVFANLGAAYGTAKSGVGIASMGVMRPDLAMRNIIPVVMAGVLGIYGLIVAVIIQGSIDPPSGNSPKYGSYSGFAHLAAGLCCGLSGLAAGMAIGVVGDAGVRAVGQQEKLFVNMILILIFAEALGLYGLIVALILSQKKSECPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C729</accession>
    <name>A0A8K1C729_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C729"/>
    <dbReference type="OrthoDB" id="155171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418315" evidence="1">
        <location>
            <begin position="19"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="501" mass="52697" checksum="0AF0302D0F2502BC" modified="2022-08-03" version="1">MVKLLSTLALTSLVTVAATPNWVGPKVGRPVDAACYRKTLRASECPLGYNSDKLGGCWAQCPVEYPVECGMECLAQSKDCTLEIITKISVVADVVLKAATSSVFSNLLGINGQVQTGIKCGVGLFNAVQKVVLAAGEMQALHPDITTDKLILELLQSSPVLNDLTGAIVTCTGAPSAVSDVAIAAIKFIVEQVAKKGSSVLAPDAFVALTAQTGIGSSIVQLQPTDMAKFKQLIAGGNTGTATCGWSLKTVLDQIIQLIINIKKVNPKATPEAIRLQLGKTDLFMNTIPALTNDCSGSTTPEAFDLRELIRKTLQTLIDKVVDAAYQNGNPVPIETYAIVAANLGLEAIATIDPTGLANLAKEFVQPICGPTTMMGEIDDGSANLALGLLTMDRAFNGSYGSWTKAGNGQVQIFFESADTQDVKVDVMSGGQKIDSVAVGKGQSVAWTKPIKDLQDKTLYLDRWRPGIFGLPGKGGGSLVAWIPHAADGGHFELHAKLNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7P2</accession>
    <name>A0A8K1C7P2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7P2"/>
    <dbReference type="OrthoDB" id="207378at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF53">
        <property type="entry name" value="ACYL_TRANSF_3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="123"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="501" mass="57394" checksum="7FAE8BCBA53E02FD" modified="2022-08-03" version="1">MERCRHQDLRVAYDILSIAGGHSETYSLVNTTTSRLHASRASFAPGVSKPTSPAHAHTVADAEYAGDDASPKDDSQLIRRRASDSEIEPPTEDSSDSPRTSSSVNKKSDVQKPAPPSAGSKILFLDGLRGLAAMMVVVQHVGYIGIPIGQPAVDTFFVLSAFLLTMIFEKKARTLLNEKVSYKRWGWALLDYFARRFLRVYPLFAIVATYLLVYSPPQKEKLFFVHHPENYNLWKVLTFKFEYRYHVFWTLPLEIAYYFLIPVFVMMVLLLKKFWIVPMLPLGYLVAYSGFYWSRGDHMPLKPHLPTFICGSMAAIVYVKADQWNTKRQFVFRWYHWLVLRVVEMSSLAILFSVLFGGLVFSWVFENPIPQTSGGHFVSANVSLIIVCEMLLPGVVSSLLEWCLLWYAGKISFSMYLLHSFVIYSDWVRRQGYYNKFFAVWGLTFLLSMVSYHLVEYPSQWVAGRLGQWIKKKDAIERERVAPALPVMSRRSRLSCSLKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C866</accession>
    <name>A0A8K1C866_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C866"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="60043" checksum="21FD7CED0B143289" modified="2022-08-03" version="1">MLSSHTPPDIKIVPIAKRPVAPSKEQLPSPTSTGVSKKVSYRNPSRTSTGLADGAAKLKYKPGKWDIWMLGITIVIGGQYISWNAGIAAGLYTYLICYFVIASAYVTLCCCTSEITGGLPFAGGAYGLARCTLGFLPAFLIGCCEALEYIVYVSTSVISLADVIVEVSPSLRSAKPLIWALFYISALYVHIKGDRVFWIFNLVIGSTSILIVVIFVFGSLPFVDYTAYAHQPSLNLVDGFAGLLKVLPLACWFFVGVEALNLASDQVTQPKQCIPYAQTRCVVTLFVTGIMVFFVTVSLPPGLASLPTELVPLNNGFEPLFNMSHTNATILSLPATLLPVFLSRATTTSGTPYMAITFGSALSYIICLVVYFVPTVSKYLFNVCITAAFMSYTGQCVGYISLKMNYRNIKSSYFHSPFGILGALYSMSVWILCIVSIIGFQGNGGQEIMIFGIVIACLTVYYYAWARKRQTFSPQENRIMLVAHVMKFNGRRAAGAGQKRKRGSKNNSGKTTNNNSRFTNAESTHMVGSSSTVGVSKVTTFFARRTGRSTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8M8</accession>
    <name>A0A8K1C8M8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8M8"/>
    <dbReference type="OrthoDB" id="67288at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="87"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="33351" checksum="9A539470E950AD7F" modified="2022-08-03" version="1">MSTSAIPEPVSAEFNLGANEYTTRHSIVSFEPSAKTNDGRLAYDVFPPREGNFSDVSGMEALNFWTDDHESSQTSNIITPRTMMSHDPYQGICIEVNNHSLSNQGVVLYHVDIKGPEGMLSTYTIRRRYRAFKNLYEEMNRLMTNYANIAAGASPVSGLESSASVPLSPHSQSQLRHQQTFTRVTLPALPSAGVWTYLKRHDIRLVDQRKKRFQEILSIAIRHPATRNSPVLDSFLSVAPSEISQRGSSYVSLHEYSVPVFDRERESIERKQRKRRVLEGRRMRTDSESNRGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C963</accession>
    <name>A0A8K1C963_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C963"/>
    <dbReference type="OrthoDB" id="61562at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442627" description="Kazal-like domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="76"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="132" mass="14350" checksum="55D68F903B1B88C3" modified="2022-08-03" version="1">MKSSLLGFALCFWSFLAFSEAECTLKRSKCLGVNDPVCASDGETYASNCQFEYTLCKAHAKGNTLTKLFKGACDDEAKNPFCYMRCTRQYDPVCGSDNKTYGNKCTLLAARCQTVTLTQSHSGACDAGDSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Z2</accession>
    <name>A0A8K1C9Z2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="645"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="606"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="911"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1080"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1455"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="920"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1080"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1456"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1475"/>
            <end position="1487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1993" mass="218408" checksum="70246156E4F041AD" modified="2022-08-03" version="1">MEAQVIKSLGKLKKLVPRSQKELKDVIDAATVSMTAALERKNKNQTDPAASASGPGGGGVGGSTEVPFEPFLLAVLTRQAKLVAIALDCIEKFLAFGFLKGNGSIPESIRKQLVQKYGKKGFGGGAGGSSSGGASGASGRDNIGGGAGGSGSGGDGTGDDGGSLNEDNWKLIDCIIEVICETNDHPDETVQIQVLRVLLTAVTTPTCEVHEHSLLKAVRACYHIHLVSKNATNQTVAKATLQQITSIVFQRMETFDQRVQEETEATLRESLQKSGATSESRPESEHEDTENGRRGGSSATGSFSSVAGGSDPAIVAAATASWYPEVVRSLQITLATKAKPPQGRSSLTSNNNVNASAIFAPSFPSVLHKDAFLLFRSLCRISMRSVAEDSPSGSANGALASGGSTNPFDDPFAFQSKILSLELVLSIINNAGPSFRRGERFIHAIRQYLCQSLLQNCTSNYTQIVGLSLQVFLVLINNFKRHLKAEIEIFVTSIFLRILQSENSSFEHKMLVLEVLNNICDDAQILGEIFLNYDCDWNTNDLFKQIVDVLAKTAKGKKDTAQQYANLSSSVRIKLQQNDAALVLKGLECMTATVASLKKAANFVESERKSRELQQQQAKEDGDDDERMAPATSPPASTTMSAVEAFDRKKRRQEELATGILKFNAKPSAGIQYLVQRGHLGEGTPRDVARFLHEHSAKLDKTEVGDYLGKEQQYQNGFCVKVLHEYVDMMDFTGMEIDTAIRHFLAGFRLPGESQKIDRMMEKFAERFYSACQPGLFPSADIAFILSFSIILLQTDLHNPNVAEEKKMDKAAFFRNNRGINNGEDLPEEYLGGIFDRIKQNPISLKEDVDLRARVGGRGGRSATTSIFGASSAVVDRQRRDAYIRERETMVKQSEALFKRRNPAISVSARQLNGNGAATSPRSSLSPGQSSQFHVVTEATEISHVRPMFETVWAPLLAVCSVIFESSDAPVAIQLCLNSFKHAIHLSARLNMPSERDAFVTVLSKFTALHTTGSRLMRAKNIEAIKALISISVKEGNYLGDAWRDILQCISQLARLQTHAQGLHADVDFFQGSGNNEKSSSGFFSTPSSSSSALSTSASKRGGFGSGSTASPSHSHRDSGTGSAALGVGGAGGMGGDEFYNPAIEDENAARVMAEIDLLASDRVFSSSVSLSDLAVQDFVVQLCVVSLSECSGVSNGHGVVQSSARHHPDSFTPPRVFSLQKLVEVADMNMPVRSRMVWASTWKVLSRHFTTIGCHDNLSIAMYAIDSLRQLSMKFLEKEELKDFNFQRLFLTPFEVIMANAVSTDIKELVLRCVENMILARVVNIRSGWKTIWGVLRVAAEMYDAGDDPHDTADRIVQLGFQIAKRILEEHFDRIVDVFVDAVECLLAFAVCGSEDVENGTDEHIGLTQLSVESISILETICIEKLATGQVIEKLFVEASASKRIGFKKKKADGSSESVSATSSPAANGAPRPLRYEKQESSRALEEEIDALSPPTSPSRRRSSFTSTSIPENGVNGGSVVYTDVAAHTRMWWPVLTALTTLAADRRMDVRLTALNALYDALERHGTKFSSGLWSLIFKGVIIPLLDELRHLEVFVEKSVRRPLKLAITKERCNPVQLQKATSTLCLERLLDTFGLYYDIVGFLPEVLFLLGKCMDTNDREEELAAASATALGNMLVAHGHKFPEDVWGLIADELRSVLTRAEPTWIFFSMNEPPSTAVLSPTNAATPPPTPFSPRTPQLIAMYPSVPGVLGFRFASTFPPKVVTEEEVNAQAVPSRTHLIVILAIQKMLGHVLVSRVPRQLALSEGHFLSLMHALRESYTFSRKVNDATDLRRHLARQGWVYGRLDARTAASDEDLPNLLMQEVQGKDEYLRVLFDLIRTSAHDEKKREDARRQMTVLVKQTFAEYLAWTAKGPDRQHTSLPVDSMQRVVRYTSLMVGALTQLSELSPQEMQRHLSWLFPLLNELIKTRNDEVRHALALVYAKCIGQLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA44</accession>
    <name>A0A8K1CA44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004374</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="720"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="762"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="869"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="948"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="986"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="74"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="405"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="722"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1047"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="644"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW59305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1292" mass="140130" checksum="3CDE4F654395087C" modified="2022-08-03" version="1">MASRPVLQTSDGPEETDYVSAVTPTSHEAKEKSIAFSSTEGEEENAETPKKPTQLVPLSQLFVYADATDYLLMAIGSLASVAAGAARPIQILFFGDAINAFNPSGATSSDEFRAQVNKVARNFTIVGVLTMLCCFLQVACWTLAASRQGKRIRSSYVSAILSKEMGWFDVNNPMELPTRAAEAAVTIQEGMGRQVGDAINAISQTLTGVIISFVKGWKLALIIAAFIPFVTLASSISIRFITQATQDGLQSYGKAGAIAQEALSNARTVHMFNSIEHFVTKYTDALGLSLRSGIRKGFTVGWGMGAIYATMFCAYACGMFFGALFIANDRRDGCTEDCYSGGRVLTVFYGILMGSMALGQAAPRIQAIISARAAAYDVFQVINRRSLIDPLSLDGKKLGQVAGRVDIENVTFAYPSRPDVQICRNYSLTIEAGQTVALVGPSGSGKSTIVSLLERFYDPSSGLVKLDGVDVRDLNVAWLREQIGLVGQEPVLFATTIMENIRNGKPGATDEQVIDAAKMANAYSFITDFPDGFQTDVGDRGAQLSGGQKQRIAIARAILKNPSILLLDEATSALDSESERIVQESLDHLMSVSRRTTIVVAHRLSTIRNADKIAVHSHGSIVELGTHDELMSIENGHYRQLVEAQNRGGDANEKEESIEEDVSMQMERVSSIRGTTRTSSRHSGKQVDLGTEDSENNADEDLPPVPASRIWKLSAPEWKFMVVGGLGAIINSAMFPAWGVLLTKIVVLFFEQRPRDDMIEHARYWSFAFVGLAAVFVLSSIGQHYGFAVVSQRLTMRVRVMTFQAMLRQDISWFDLDQNAAGSLVTHLATDSAILQGMTSDMLNQRLVTVASLAIGFGITFYSSWQMTLLMIATAPVVLFATYIQTKIFSGTLGNRKANDGDAAAGALLSEAIGSIRTVASFNMEKRINFAYVSVIDSLMASDTKGGVIGGLSFGFSQGILFLNLAFMFYIGAKWVSNGTITFEDMFMTIMVITYTMFSLGIAAQNKATQAKAKTAASRIFSLVDRQPAIDATSTEGTVLTQLNGDIAFENVAFVYPSRPDAKIYRNYSLRIRAGQTVALVGASGSGKSTAISLLERFYDPAHGRVTVDGTDLRSFQLPWLRDRISLVSQEPVLFAGTIAENIALGKPGATRADVIEAAKKANAFDFINNFPNGFDTDVGDRGAQVSGGQKQRIAIARAILRDPEVLLLDEATSALDNESERIVQDSLDKLMSLKRRTTIIVAHRLSTVRHADLIAVTQDGAIVEQGTHEQLMSNPAGVYRRLVTRQMQGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAE4</accession>
    <name>A0A8K1CAE4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF866 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAE4"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17894" checksum="D070461F6F3D1852" modified="2022-08-03" version="1">MVLFVLYVKADLENIDKLVAPAFHQWCIDVKESNGDETREGVVVSEEELLEVDGSRGEVHFLLKWPGAKKQSQLTVVRDVKKLTRPVTGEDSGEYVPFVGFECRGLEPYAWHPGSGYTVTSAGGTATFEDVDLADDWADYDDEGGQSVGVYGVEYKFEVHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAP8</accession>
    <name>A0A8K1CAP8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAP8"/>
    <dbReference type="OrthoDB" id="99416at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="108" mass="12060" checksum="0A725C21D1167EFF" modified="2022-08-03" version="1">MSTARKASRAGMGVGKLWLTDMGTVPVLVCAGLATVAGTLTALRTISKSPDYFVDKTRRGEMLAHQSEQGSEWRAPRFRYANLVRNPINQSRQFDDLFAKDENKDVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB88</accession>
    <name>A0A8K1CB88_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB88"/>
    <dbReference type="OrthoDB" id="122626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="450" mass="51010" checksum="72E8FE43B9AC1428" modified="2022-08-03" version="1">MAPATTEELETLLGVECNPDATLEAALAFVDEFQCQEESQSSQGTASSSPTAGSTHSSSESACNSDSSPARKASQCQETASGKKPRARKPDRQRQELLYLRETVGDLEKKLSELIDEQRRQTQRLAGDSAWANFASRQLGERKRAEEENATLRETYEEQLRLAKSLERMLKKRGYMELLGTDSHKDGLKRARGQSKACSIYSMEQVEADLKRSVQEMYERVDMMFVDPQFAVQDNVTPKRVVELLSDAVTGTMVRSVDSRVLPFDYVETADAIWDFVMDRVHVKATCSCQNIRHEIDLSKSTKTITGQMGWLGTKHQFRVKCVAERYVEPNRVVIVSCMLLEPAQLGDSRIDGIWMRVRAWHIIRRGPNDCPERPSTLKQTYFVATPEIYAPEDDFSAEQWRQESEVGALTDFVLHAVNGQMDFNNQRVENRLADQLLQLQIENYDSVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBU5</accession>
    <name>A0A8K1CBU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBU5"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050858">
        <property type="entry name" value="Mal-CoA-ACP_Trans/PKS_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681:SF1">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="6">
        <location>
            <begin position="7"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="34383" checksum="880CED2950101D76" modified="2022-08-03" version="1">MLKRALVFPGQGSQRVGMAKDLLENWRVAGDVLEEASEAIQFNLHKLMTDGPQDELTQTQYAQPAILSHSIAVLRILEQEKGLRVDSSARFVLGHSLGEYSALVAANALPFAEAVKLVHFRGQAMQRAVPNGVGAMAALMPVSPLDAEEICRSAAERAEAACQVANYNSSKQTVISGAAKAVQEAVEIAKTEKKVRRAVLLDVSAPFHCALMEPAARELEQHLLELTTSIQKPTVPVVWNVEAQASEKDSAGIQHVLVQQVVQPVLWSQSVDYCLEAGVDEFVELGFGGVLTGLIKQHAPKASTVSCGTAEQVRAFVNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCC8</accession>
    <name>A0A8K1CCC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCC8"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="78"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="29188" checksum="5DDF65C6A7D577EB" modified="2022-08-03" version="1">MMLNMTRWTRLARPSAAVRASNALLNGARRPASATVRFLSTEVDDVQSKSSVLPTHIKFRMPDLDFEHVLGGDGGVTLTKWQIQEGQEIKDGTHMCEIDTPDLVFVLDSGDEGYLARLLVPEGAKDVPPGQPLAIIVPTKEDIEPFIDALKQNPTAIEGYVEPVVIEATPAIETAASASTSDSVDNSDGAVVLRHLHKLHKEGHFADEKIFKTLKSLARKNDAQLLVTYKGSFPSSGARDDATFDVEFFVETAVELAEEALASDSSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU1</accession>
    <name>A0A8K1CCU1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1483" mass="150868" checksum="46ECA4E73654AF31" modified="2022-08-03" version="1">MSSVSRAEARIEATEATSQPFEVAESATSAESKVDAIAVDEAVMEPGAKEIVGATVKVPADAFTEAEVNAAVEEAVEVPVETVLVAPIDAAVKEDVDTTEPETDVSLEEMSVESPVDLPVEARIGTLVIVADTPVSTSTDTRFEAKVEMVAEALVGVGVGEEASVEVSVEAPAEVPVDASVETADDASVEAAVEALVEAVLEAPPETSVEGSVELLVEASVVALIEATVEVPMEASVPKSTEATAEAAVETTVAKGHALVDVLVKTAVEETVAVLVETCEEEATAEVELIVETPAQESADAPVEVVAANSPVEAVVEVDAQPSVDVSVQTQVDVPIKGAEEAAIETLVDMAKVETDALVEVSVKESVETLVDAAVVAMMAEAESRMETVVDALQGVDIPVAEGETTVEASVDGFVAQPIHAPIAGAETPAEILVAEALEVAVDAVVGSSVEAAVDIPVQAPVETSIEAPVGAHVELPEQCAAEATIEAAVDTPMVEAIPMETPVNAALDTLAETLALGYVKAALESSVDAVVRTAVVSPVEAPEDAPVGVTTESAVETTLIDEQMPATATPLVEMSEEAFEKARFEAHAEAAAEVPAELSVKANDAEAAACAEDQVTEAVDPPEEASLITPEETAMGSLETTVPEADVSVEAVAADVEMSDEAHGGAGAEPAAVNLPPEGPAEPVSAPEEVTSESTIRAPVELSDEVKVVNADIPAEVSIRTAVEVGEVLAGSIVEVSFVEAPVGVPVDELVEAAVEALVTKVELSVDTSVAVETLDKEEVEVPLVEENTPVDMPVEALVDSVVETLVDAPGDAAIESSVDSASDAPFDAKVAEVEMPVEKTVAESVESPMTEVDALVEAPEGGAVDIALVEVEESIESSVEVPVEPAVEATRVEAELPVEESVEASLVAIVETVVTEGEKREVSVEAGIEGTVVDTSVETSIGATINEPFEAAIDAPVIATVESLLVEVEKYVDTQEVAPTGEVGETEPFEEALVEAAVEHSFEASTDTPFESTVDSPPSEDVSADTAVVSPVEVGAEAAEEVAVDAPAEVAVDGAGDTMETAVDVVAEAPVEATVDTAVDATIDAAMDTAVAAVVEAAVESSLVEVTGEAKVEVPAGAPNEVVVEDPPELAEEVKTAAEAPVKISAEAEPAVEIASFGNVASGETAVETQAEAHVEASVVAAIETALADEDASVEMPVEVSVDGPVGELAEDAMGSSTTVSKEVQLETPIEAPSAETMIALEEHANAPLESLTERPAVATDTHVEAAVCAAVEALVEASIAGPAVPLAVETETLMNRPVDEAVSTLLDESKGPVETKSPVDAPVQASVEALVEMVVAKAERSVESPAGAGVEFLVEVATMASVETPVQTPVEVFADASVAVEVILAPEVEAAAVAAADAREGAVTAPVDVSASNGERAAVEKAVDAARLSIEAVEAEIVENVSASVEGVIEAVVSESVDLAVESLVSSGSGVLSGNQASLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD05</accession>
    <name>A0A8K1CD05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD05"/>
    <dbReference type="OrthoDB" id="201018at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="497" mass="55935" checksum="55F8E7DA73586BFC" modified="2022-08-03" version="1">MDTIFLYPCEELFESHMTMLTAQCTIAVSEATLMDNMTSFLMEDPDTINLETNWWHPRVKVVEKWLREESHRAAIPEDGTEEMIRKHIQRGDIYAHIQLKCWKHILLELLDIPCFYPDNRDADGEMGQTSPSRGKLRPGKELIILSDDPSQPREPEPLLSDDGARSETPSEIVLSATGSPRRVMQTDANANSASTRKFANLSMMERQAEWLRKKQEKMEAEKQRQDAEKEKELTFQPKLMRRSTYSGDKPTKELEPQQHQPTTTSKPTRTEQPATKRPPSGNPASRGIPKATPKASSKKKKNIPTTQPIEISSNLLDSMRNELEASMSVSTTRLPELPSEPEEATDNNNNSSTTSLGPEATLTANANAPDPSQADLKAWSSTPFISGFRVDFDSSETKARLILQDASRFELSSMYRKTDRKAGRDGIALHMGRREDTFEEEVIAVLFDKEKVSEADAAKWWKDHEHRFSQYIRDRTSTGAANALASAVAALASDGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD33</accession>
    <name>A0A8K1CD33_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-queuosine alpha-mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.110</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000871</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12885"/>
            <dbReference type="Rhea" id="RHEA-COMP:18572"/>
            <dbReference type="Rhea" id="RHEA-COMP:18581"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="ChEBI" id="CHEBI:194442"/>
            <dbReference type="EC" id="2.4.1.110"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:12886"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.110" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD33"/>
    <dbReference type="OrthoDB" id="10032790at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016438">
        <property type="term" value="F:tRNA-queuosine(34) beta-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01635">
        <property type="entry name" value="Glycosyltransferase_GTB-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051862">
        <property type="entry name" value="GT-like_domain_containing_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022701">
        <property type="entry name" value="QTMAN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13615">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13615:SF3">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12038">
        <property type="entry name" value="QTMAN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA-queuosine alpha-mannosyltransferase N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="7">
        <location>
            <begin position="154"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="40235" checksum="1098F6AF953EE940" modified="2022-08-03" version="1">MYFSTAIPRSESLRVLFVSSMVNLSELLGLRPDLARPHVKKIYYFHENQLTYPYQVPTTDGESTERKAKRRKVAAEDFQITWSQIISCLAADELLFNSDFNRTSFLSRIDVFINKIPEPEMRHRGLAKQLESKSRVLYFPLKMLRVPDATRIDKPSNLVTILWNHRWEYDKNPDEFFETLCELATGGSKFQVIVLGESFPESPAVFRTAKETLEASEHVKIAHWGYASSREQYLDFLRLADVVVSTSNHEFYGVAVLEAVLCGCYPLVPNRLVYPEFFSGANVFNTQRQLFKKLKYFCGNPIPARRFAQEHGDEFIKFTWQSLESEYAALLVPSSTDNETTIPRRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE16</accession>
    <name>A0A8K1CE16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional repressor Tup1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE16"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="350"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="390"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="432"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="60628" checksum="472E5222FC84CE00" modified="2022-08-03" version="1">MYPVGATSPAIGEITKVTSRISIGATLDQIKNSYEAIVQQLHAANAAQHELETQRQAQLEEINAIRRVLVVLEANHQRVCEQYEQDLKHLRHQVEAMSRSQVASALPTINKRQRLSPPEERPSTMTSPSDRSTKQPSGDHVAIVPLLRPGGVSKAHSPTVPPLRTLREVTPAKQSSPSATGQTVKTTKSSPPTKPTNNGSKTLQTSPSASKEVKRVKPPSTKTPSTHKWTSEYSPSNSGQERPVTTIHQAIDTKSVVCSVRFSPDGDRIAVGGLKQARIYDIETGETLMCVSPMDHGGESPTQESEESEQHVRAVCFSPDGAQLITSMPHNSNITVWDVHTKIPTLTKTMNGHTGPVYSLGYVDHLIASGSGDRTVRLWDARSASCRAVFDGPTDGVTSVALSPDGRFVAAASLDHIVRVWDIEASRLVSSLTSHRDAVYSVAFAPDGATLASGSLDRSLMLWAMNMQGRSQSRPQEIFQGHKDFILSVAYSPDGRWLLSGSKDRTVKFWEPRSARATLTLGGYRNSVLSISSSSSSSYFATGSGDAHAVVYKYQSTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE80</accession>
    <name>A0A8K1CE80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">33 kDa inner dynein arm light chain, axonemal</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the inner dynein arm light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE80"/>
    <dbReference type="OrthoDB" id="273640at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183:SF0">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183">
        <property type="entry name" value="AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="182"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29555" checksum="107EB781C35BE67B" modified="2022-08-03" version="1">MIPPQSSLVKYNSPILVSTTKEKALKSKRNAAAVPGAPSGKSNQTQPVEPPPKPTVFTGSHSQSQSQTEDILNSILPPKEWTEDGQLWVQYVSSTPATRLDVVNLQEQLDLRLQQRQARETGICPVREELYAQCFDELIRQITINCSERGLLLLRVRDEARMTIAAYQTLYESSIAFGMRKALMAEQKKMEAEQKIRTLETENRELAAQIDELATRCEAVQRREEERKTADEKKHQEEVDILRKANDQLKANLETLLAAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE96</accession>
    <name>A0A8K1CE96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_010902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE96"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="207" mass="23324" checksum="D454AAB9D7BB55AA" modified="2022-08-03" version="1">MVLTIRHPAPEFTAEAVVNGEFKKISLNEYRGKWVVLFFYPLDFTFVCPTEIIAFSDRVEEFKALNTEVIGCSIDSKFSHLAWINTPRKKGGLGEMQIPLIADVTKEVGTKYEVIVKDGDDAGVAFRGLFIIDPKGVLRQITINDLPIGRNVDEVLRLIEAFQFNEEHGEVCPANWKKGKKTMKADPKGSLEYFDTVEEPAKKKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEY0</accession>
    <name>A0A8K1CEY0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_010836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEY0"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="699"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="804"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="886"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="3"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="323"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="649"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="982"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="578"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="597"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW61773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1224" mass="132605" checksum="B2193F2D3E06663B" modified="2022-08-03" version="1">MLAVAMLAAAINGAVFPLMAIIFGNAISGFQTPDGGVDRDAVNSAALSYLYLAATLFITDYLGYVLFALTAERQMQRLRGAALKHMLHMNIGWYDARDAFQLSSRLTGDTVKIKDGMGYKLGEAVKMTCSFVAGYAIGFSKGWDMALIMSCPMPISVLSLAYLLSMLRTRAEVSQQKYAEAGAVAEETLGSIRTVASLNGEHRAIAKYNVRAVDAEKENLHLAKYSSIAFGIFMGSMWVMYASGLWYGGSRVAAAKISPSEVFQSFYGVLMGGMSLAQISPNLNVVMEALGAAGALYEILDTPSEIDVNKDEGTIPESCQGRIEARNIHFAYPSRPDAPILNGYNVTIEAGQTVAFVGSSGGGKSTLIALLERFYDPQSGQILLDGQDVRSLNLAWLRSQIGLVSQEPVLFAGTIYENIAYGGNDISREQAIEAAKMANAHTFIMSLPQQYDTLVGEKGVSLSGGQKQRVAIARAVVRNPKILVLDEATSALDNESERVVQAALDDLMDKTKMTTIVIAHRLSTIHRADKIVVLSGGRVVEEGKHDELLAIPSGVYRGLYTVQEENAKEEAEAVATQLAAVSDENPIESSTDRNSLRQRTLSQRSSKSSVFSSVHDDVDNDKEEDAESTKRASVKDIFEFGRPERKFLIIGALAACLCGSALPGSAILISQFVATMTAQYGKYLANGDRSFLDDLSSDITVYGVCYLGGAVFLFFVTSTQGYCFRYLAEKLTSRLRDVHFSALCRQNIAFFDEQKHATGALTADLSTNATKVAIITGESLGRAVQAVCTVSAAIVIAFATGSWALTLVMLAVFPLLIFAQHVQMKVLHGSGVFSDELNDVGALASEALGNIRTVVALGMENSLTTKFDRLLEVPVRKGRKEAQINGLSVGFSIFTFFAVYALAFWYGGILVERRSITFVELMRSLMAIMMSSQSAGSAASFVGEIAHAIKSATSIISVRDRPLPIDSFDKDGDKPQHVQGKIEFNDITFRYPTRPNVTVLKHYNLTIEPGQTVAFCGPSGGGKSTCISMLERFYDPVEGQVLLDGRDLKTLNVQWLRRQIGLVGQEPTLFVGTIAENIAYGMDTTPTQEEIEAAAKMANAHDFITHFPDGYNTQVGAKGEQLSGGQKQRIAIARVILKNPSILLLDEATSALDTESEKVVQEALDKIVTLQRRTTIIIAHRLSTIRKADKICVVSGGRIAEQGTHTELLAKNGIYKRLVESAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFD5</accession>
    <name>A0A8K1CFD5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFD5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035432673" evidence="1">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="22049" checksum="4FEEA4234017CACA" modified="2022-08-03" version="1">MYQSFLTTFAVSCAPLVAAAAVYATYKIKEAAREECRRQGEEQHAASMATAASKLKAHERIAQAAHEIADAMTVDIHEAVGDYEVERPRKLKAALEVATTKDVIELAGAIKVKDEEIQEVVLASEGLRDRILEIRETKRQVVQDIESMTTQIVTVQCRNDEMVKSLRKDLAGLRDDVARWSYKIAPFLSATHPAVAGALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFQ6</accession>
    <name>A0A8K1CFQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Damage-inducible protein DinB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFQ6"/>
    <dbReference type="OrthoDB" id="158485at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="entry name" value="dinb family like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302:SF1">
        <property type="entry name" value="PROTEIN DINB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37302">
        <property type="entry name" value="SLR1116 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="19380" checksum="20F8DF1803ACBC2E" modified="2022-08-03" version="1">MALRQQLLTMARYNLWATRELFAVVDTLSDEEYRRDVGLFFKSVHGTLNHIYVAEHDVWYPRIHDGVFPMDVALDSEVENDREKLKQMLLTKAERWVPLLESCSDERLEGVFEYHNLTGVAITKSFSLIMAHVFNHGTHHRGQISAGVTMLGHPAPVLDLDYMPDDLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT6</accession>
    <name>A0A8K1CFT6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009478</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT6"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30804" checksum="9E04AD19104E37A4" modified="2022-08-03" version="1">MRGCGRWLRVDTRPVARSLHTVRRVGEPETAVCRYFFYDQLGRKQSPWHHVPLFSEALQHPHEEANRIFHFVNEIPKGARAKLEIAGDEEFNPIKQDIKKGKPRFYHFDSLVNYGCLPQTWEDPNHIDDDTKCGGDNDPVDVVEIGSRIASVGEVYPVKVLGVLGMIDDGETDWKVIAINVNDPLAPHVNDIADLTKTPLHDIVPQIHRWFRDYKIPDGKPQSQFAFDGKAMPRDFAINVIEQTHESWKHLVGDTLGTPTKFWTGNSPHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGC4</accession>
    <name>A0A8K1CGC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">CCR4-NOT transcription complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_005642</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGC4"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="12"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="113"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="254"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="322"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="587"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="590"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW63024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="756" mass="79195" checksum="736884A1ABE818DB" modified="2022-08-03" version="1">MSSIDEEENECCPLCMEELDLTDKTFNACPCGYQVCLWCWHQIKNEYNALCPACRAPYAELTKQKAPLDREDVLRRTKQRKQKEKSERRTASQSKIPSVNRKNLANVRVMQRNLVYVIGLPQQFADEDILRSNECFGQYGKIIKAVVNKSHLNSDRANATASAYITFSNKDDALSCIIAIDGYYIDGCLLRASFGTTKYCNFFLRSLQCNNPDCLYLHELGDQDDSFTKEEMQTALHSGKAAFRDLTANEVRAGPRFPPPFKLNATEASAASRSSPGAAAAAGTSSPGAASAAPASADAQRKAQSAAAIYKLQREDSYSRIVSGGALPRGPDTELGPRLVSTDSGAFSPPPATATTEDRKPDLRVDTGVGLMDSVVGPLEALKLATGSTSQEPAWAQPFPSPSVLQSEPDDVIAPPAPVFSPFGMGFNGGIRANPQTTNDPWRTMEAEPLGGPGALGDLGSNDRSSFRSSQPFSAPFASAPESPKGLSSGGQLSFASIDAIFTPRNEPSEALAGLLGMQMNSAAPLVHGPPKPVAPAVPKTTRSSRFAFANQDSAPPSSLGGLGGSYNSLSDPALASPFGYSGFGGAPNGSPNATTPFPSTSDPSAFPPLGAGLRSSNSFTSDSGDAFNSHGGFGASSMDSSSSGLAFLQQMLPNVNISFGGEYATTGGNPRDGMGGSSSAGNAWGSSGGLNGLGFDSRPSNPPPSSQFYDPAIVSASSGLGGFYGYGNGAASEEERRLESAFGGGYRAPGSVMDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGD0</accession>
    <name>A0A8K1CGD0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGD0"/>
    <dbReference type="OrthoDB" id="165533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="583" mass="64904" checksum="181178A54EB548F5" modified="2022-08-03" version="1">MAARFFEGDDGPFPRVCLSRAEPDTCRTFCGLEPLENVDVASQLDEILTRLAPLVDEELVQRPIEHKLSGIKSAREETETFVPELVKHLASEEESHDLRRPRIILQELAYCWSSIGIHELWSIPIAADEVSFATSEDTSSVDLARYILSALHVRNSEDIAHVKVLRVARKSVTASQFAALCSALQYARILHTLDFAKSSRLTSQDVAWLGYALFHPDAATSSWWRLILTYALEECASAGQILQRMALGNHLTSILAGSLDETTSVYYSATFHPETEILVDLMTVIADASARYDVCVDSDDLSQLPDQVPVVVSGFGLGSVSKSSIAIIATRPPSPSVLTSLDYVPGEDLEAKLQILELLGSNLTCFYAERMGYIDSATVGRILRVCPQLTMLSAKHDGSYWAGEEVGAFYSDPVLPELSLKIEKNVFVAPSKAALTTSLCQLQVFRLQKDRLGPISTSRDSVVTMIRGLPGLRYVHHDGFRQWEYPVQVLSYADGRKLAWDTLQIELDDLLTLAHDMFHPAHKRAFLSVVRTHQTREQELEATAIARLDSSLLSNIFAFATSLVPREVWVGYYNEHHSRMSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGJ7</accession>
    <name>A0A8K1CGJ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGJ7"/>
    <dbReference type="OrthoDB" id="299625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="439" mass="49580" checksum="900A88927A1044CF" modified="2022-08-03" version="1">MSQEPAEVFSKDTFLTALRNGSTSHHDTANTAPKSTVEEPAAMAMVREKHAQLHEVVGSLSDKISAVLGRQEKDFLAAYRAHMYNVQKELHELREKIHRNETVENKSEKIKKIEEERDWYRREALRLDAFTTAMTKDLKYMREKLESIEEDRNWLEKQLKACKKQNKLLRAELDVRIASGANGMDGSFLPPFDSPHGSFNAGKKARRSSDPRDESSLPQLSSDLNSPTLVEEREQQFRRQIKALKKELQQKTQTIGAMRKQQLLFGKDCGVLGESRSHLENFFLQCVESVKVEVMKRRSAAVDTNHGRSDKARNQKRDVGTELEDFSSSDRVRVIERLLAHDEVLTLLYEHLFSSPQSSRRDRPSTTDSDSRHHDSPLSPSDSTKSLPEMASPSTRKVSFEVNERIGQPAGSGAAAASAARGSGGLPIDDSTRDYLRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH50</accession>
    <name>A0A8K1CH50_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH50"/>
    <dbReference type="OrthoDB" id="164681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="42406" checksum="6A997152E59728BA" modified="2022-08-03" version="1">MSTKRKLSELETSDPADLEPDHSSPASDEVVAESSDDPEELSTGITGHEAYRDAPASPQTQEALEDEIETLEAVIQRLDQEKHALKMRLNEIQYHQKFNVNDCKKWLAANFDFDRKDTPELLAGIFENYLMQNDTLEPLPHQLMVKNSNRAQARREKLVHKRSQYRKEKDNKKQVEAQTARAKKVSTKGQDGSSSDPGAYGQFLYLHPQEIEQFYAEKPWMVLDNRFPKIRPTAKQSDISELVEQQERFLKENLWAIWERYHWFPIKHENGKSPEEIKQLGTHHNRRKRRQAQLKERIELLNTELKSSVDKSVLEQSVFGDRWVEIIMKRPKLWLPREDESLLAQLEELDALEPDRNFNFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHJ6</accession>
    <name>A0A8K1CHJ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHJ6"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF70">
        <property type="entry name" value="SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="175"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="227"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="283"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="333"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="42137" checksum="7F6BC8E476BFDE3F" modified="2022-08-03" version="1">MTRKLFIWGSGGSGQLGLGNDEDYALPQEWTPRQEILLDTMTTGGCHTAARDSESRLYMWGDNEKLQLSVNAGVKSVVGPMQLPLSQITLVACGWSHSVAVAQKKASQEDADGATIEDDEQELLTWGAHHHNQLGRSSSPHHPGHVVIDGGLTRGRHVVSISCGWKHSMVVLADGSLHSWGTGRHGELGLGKEQLVAPHPTKINMVEPCDRVYCGWQHTIVHNTRTGGVYACGNNRHGQLGVPTTQETARYQFQRVEISSDTALHVRQVDVGWHYAVCLASDGRLYAWGKGTHGQLGLGAYETMQMPTALPFEGRVQALACGSEHTLVVTEDGGLYTCGWGEHGNLGHNDKENRSLLTRVAFFDDNQQKVESIVAGGAVSIAVARSVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHS5</accession>
    <name>A0A8K1CHS5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHS5"/>
    <dbReference type="OrthoDB" id="166387at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="39341" checksum="9937E8D2C3012615" modified="2022-08-03" version="1">MMMLVRGAERDDMVVAESCPSPRDVDMLLPSVCPEIRRASSFRDETIATRRVATQQSEMEEKGENTNEAKDLETGLQEENVEDEDRGDGEEEDASEIMSFEEYNVADIDSLEIAPSQDFGGDVTRSKREEGSMLGSFQRHTCPWIDFRDGTQFQDDDESEVFDNVIYAPGARMPAGVHKPSQVKKESSFESSTCRSADTSPSGGSKATSPFSTTVNPSTEPKPPSPFTTKATEEPEDVPLWRQRLSVKRDCSFVDGSDFSVMSPRRRCTALVQELSLDCPLSRLASEEKIKLLDDECVPSSPLRQTSEVDDTPVDSTTIEGSPSSFFHRRIKAKRRKVRQLALDGFLQPRPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHV0</accession>
    <name>A0A8K1CHV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHV0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="131" mass="14714" checksum="9DF50F5F0C5E67A7" modified="2022-08-03" version="1">MRGLMRAIGLGGLLRNTPRVQETLRSQRSNGHLSALRPIDMGSLRSLTPRASEDRESDIRVSVERPQFLFFAGHDPSPWSLQLYAENNGQPALSTAKYPFVPSTVEPIRAPVISRQMPVFFAPQYVNMSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIR6</accession>
    <name>A0A8K1CIR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIR6"/>
    <dbReference type="OrthoDB" id="113054at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="22231" checksum="0FA03E5C6DA00E69" modified="2022-08-03" version="1">MPAQERSMGLQPLQLVPLMPDAYTERAQAMSTLRRIGRLEISNQASTDSHQRRYVINISWKLSQSHIPTNLRVNGPPDVRVEREYAEFIQLRKSLLKRIDEIHRMMPCALCRRVMECCVLDESQSLFMLKLMYKDISICNMVNQFVKCLLKEILQSKTRSTRRCLLEKEVPLKLKAFLLPVLETDVGPENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA3</accession>
    <name>A0A8K1CJA3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014201</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="784"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="863"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1306"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1946"/>
            <end position="1967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1973"/>
            <end position="1992"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2012"/>
            <end position="2034"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="362"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="1538"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="2117"/>
            <end position="2240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="489"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="546"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1707"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1759"/>
            <end position="1790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1707"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1760"/>
            <end position="1770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2369" mass="265750" checksum="2728C6564FA46614" modified="2022-08-03" version="1">MRRTSSLRALTSTGPTQEARYVGHGSVDWIQFDPRNAFDPHSRFLNAWHQLLLLALVYEAVVLPFTVAFTRTETSPLYQRAEFQVLYALESLFVVDVYVKLHTGFYENGNIHRDASKARIKYLLSPAFLADAVALVPFGLLGVELPIPTASRAWLECHKLVRLWRVPSYYATLEDLYAKYFVTHKMIKVLASTAFLAHVLTCARFSFGYAGESDTWLASPLTNSANSSSTQYLQAITWTFGLLTGVLEGARPRTTDEFVFTLAVMLAGLVLATYLCAVFFVLAKSEQSQAAAIADARIEQLKHLLSYHHVPEHLQLQAVEYIQRYYTDAESNDRQVLKMLCPSIAKDIQVELLRDTVATIPLFKSCHPQFIVAITSLLEMISLPADFVLFAAGDPGDCMYVVNSGVLHIIVNDIKMRELRSGSFFGEVSVFAKRPRSATVVTTSYCTLYKLSRFHVERVLEGYPQYAEVIARAVESIVKQQQAANHEAQVAAAARAAPKPPPAASNGGEETSESSAPTPSPAPATTGLEDFALTTLYRVSHEANPAAQENYIQRRRQTLKRTSPGKKKRPVLGRSKSAQNVSIARREELSMLSRRSMNEHTTTGEQSGETVAAEAMPRTTTFVPSPPRVKRSQTFIFGRKVPPLTLQTPAWLARTASSQQANSPRRSEARTAHGTLIYDNASGAFLPLISPERPPLWTKLLLPECIRRGSRFRLVWLVVLQVVLLYHLVLLPLQLGFPLLRNATWYVQTLNALLDIVLVVDLYVNLHLEPPVAKKPTPRHTARAYVLSPACLADVLAVFPYWIFAPHFMPSAVLRLPRYLRVWRVFDHTTEWHSTRPTIVVTETATAPQRRQASAFRTRIQRFIVLLGLLALALHLLACVYFGLTELDGFGSDLLDMDSARSAAPYLVARQYFWSVYVAATLLTTLGRPPEPQTPRQFVFTLVCMLLGLLWTTTLIILVQKRFTTASQEQKEFLTTRARIQAFLHSQNAPLPILTRVNAFLDFWWSAHRGAIVGELLNELPETIKRQIVQEMCKPAIQTLSLLADVRPVLDDLERVFVDNVQFILYGQGETIYREGDYASGLFFLLEGDVCMIAHGGEPRIVPRGSFFGTAALHLTETSVSYAERMTAISGCILVYVAREHLHAMHKTFPTLSMALKALEKRIRNTKSAARAHALGSARRSSTGTHSFTGLDPGKLKQQKKTLLARIFHVDTDAQVVFDPDAPSSSAWELWILVLVTVQSFKVIYEVCFGITSRAWIIQSELLTAVLELFFAMDVIFQSRLGVYEYGNKILDVPQLRQRYFHSQRFVLDVVALVPLFIINWGLGLRGRVELLNVHKLVRLLKATRALSAWETQYLNRTLELRVVKLVYWTLLLSHTLGCVWFSFGFSPSGSSWLASEQVLGSSSRKHQYLASLYWSFGLMSASTAGERPETALQSAFTVLTLISGLLLTAYAIGNLTDVVELMGADTREFNRRLSALRHLLTHFKLPATLEDKLKTYSFFQRFHSITQEHVLERCLPPSLLTDIRLVHLQPMMVQVAFLAGMEASVTRMLVAQFVQVLIVKDEFVCRYGEEGTDMFFVFTGVLDVMVPASSLHRLSSDVPATSGLMAAVINKSAGGGFASPPQMTMKKVNELRSGSYFGEIALFGNRVRSAHTLARTSCVLYRLSRRALELVFERYPDWKKNVLKIVSIQQEQQHLRTLYLAEQQHDASNAKQDSQPSTSATVTPVLIGRRRSAKPDDTIPSASQFRQSARRLVRRISNHKTPTGPSQAAQAKMEPPPEPAAPPTSTTRSTTASTLWIDTLLECTHVQSPTHVRWLQTMVVATTFMAISVPYRIAFHPLDDLSALALTVHVLEHTCELLFAWDIWMNWNLKESLASLELYEQRHRTAYTKTRLRWDALAAIPIDHFLSDFYVSPWLRINRCLKVLNLASYLEESQRRSVRYALTRLLSHWLLFSIAIYWCACAAHSLKTSHTSNASASVVLHSIFFAATMFFKKGPTLSPLAAPSPQLSFTLLVAFLGLLIMALLIAEMANLYVSFISHEVDFRKHHLAVELYLERWRVSGTLRQRARAFLSSLWSSHRGVNYQAILDDIPLAIRCEVVQHIAQMPLQRFLATHFRAFCGEEEKELTALVSALAPQLKYEGYPRDENVLIEGSIMKEMYFVVSGRLVALKSGNAVAGSTPTTPPVVMDHATRRASLVRFQGGDYFGEKGLLGYSVSESTVKTVRACDLLSLSSEALLHALLGRPLFQTALSLAAECYREMAVNPVHTGAGNDEAWGALLLLVIARRQRHWDQLYEAGHQSHAMRKTLAPLRTLARPEDCLRVFENLLRLIVPHGSLQWNRRSSSFNSVSSHMFQDTLPVMHATTLAPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKQ2</accession>
    <name>A0A8K1CKQ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKQ2"/>
    <dbReference type="OrthoDB" id="1929311at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032704">
        <property type="entry name" value="Cms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030:SF0">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14617">
        <property type="entry name" value="CMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="32906" checksum="7012886C4C934CA1" modified="2022-08-03" version="1">MSKAMLNDDELEQNWAPEGVDLSDDEDVVSVGSDDELEDDDDMDAPSTKRTRGDEDESDDEEDDGSDDDKPATKKQKNNEKVSTKKEKPTKGLHKVPVAEHFKIVNDFYIKQRGGQMTTLELAEGLAESHFVAPAGLGKHTLPNLSLYMRHLRPAWKVDFKGKGKKYDKSTYFLVICSSALRAVEVLKHFGSFKCKVAKLFAKHMKVEDQEIQLAKTFNPISVGTPGRIKKLLEINALSLEHTTHVFIDMEKDKKAMTLLELKDTAKEMMELLQFHLLPQLKADKLKLVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKX6</accession>
    <name>A0A8K1CKX6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009322</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKX6"/>
    <dbReference type="OrthoDB" id="147652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479169" evidence="4">
        <location>
            <begin position="25"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="59166" checksum="FDDDDA1C1D0DA2C2" modified="2022-08-03" version="1">MRVASLFAGLSALALSASVPVADALNVAIISTFGTRSDIAPIFEGLRDFAMVPGNKVTFIAAGKGLASGYASNFKEYVETVVVDELELPEYLDTFIPQIMEKNLRIDNTAMFLDGINLIADVYETNVQIFMEQFRKYKFDLVMCDAVEQSCMDAAKETKTKLTIYGPLGQYGVGADWYVPDFLDPVSVGDWIASPWRRAKGYIDMIPFVFAMLQARSKIIAAQAKLNMTMEYLEPWDYPQRHMMLSHHVLGIDPARSVPTNIQVFGPIVHEANIPPLEPEFQVALDNFKAEGTRVVFIAFGTLLTFKKGHVLAEELLAGIETLISDKERNVAVIWASRHHHHDMIAPLQAKYPGRLLTPTWVNQRRCLMHESVKVMFSHAGYGSMSEALLEGKAQLMMPLVFDEFLNAHLAEEQGIALQMDKSTMTADEMATKIQWLLDETANPASEYSRTLQKWQTIGRLGNERAKVIVSNAVTLAATVGVDHLVPPDVKLSIFDRFAVGPMVLIFFALRWLLSFACASSRKTNTKTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL28</accession>
    <name>A0A8K1CL28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL28"/>
    <dbReference type="OrthoDB" id="45342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59690" checksum="544A71B3C37C6342" modified="2022-08-03" version="1">MNILSQLEEPNVSLLAGTALAVLAVGGLTMRSTKSKNAPAKPRKIHKPLTTLPILGNSLDAIRTAERFHDWLLEESLRVKHEPWSFKIIGEEETLILTSPEMIEEVTSAQFEKFIKGRYQIDLTSSFFGMGVVSADGERWYHQRKTVVRFFSAKVLDAFMRHSVNKNIHRVYSIMDDTVAKNDSIDLKRMFHDFTVETFAEMGLGVELNCLGAEKVHPFQEGLEAAGKVVSLRFRRPEWAWKLQSWLNFGEEAVLTSNMKTVRKWLHEVVAQAVQSCIDKKKSGETTSQVGKSIIELFMDHSEDDLAGLSQEDLAEFVLTLIVGARDTTADALTWFFHLLGKHPEVEKKIREEMATQLGDVVNDKDVYLTTEHTKHLVYMEAALKEAMRMYPPIPFTFREAAEDAVICGDIFIRKGQKVVIPQYTLARSPIHWGPDADQFRPERWIDPETGRVKQESAYKFFNFSAGPRMCAGMSLAYLELRLLTANLLKRYRFEMDPNNDGSYDMAVTLYMHHPLMAKPIPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL84</accession>
    <name>A0A8K1CL84_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL84"/>
    <dbReference type="OrthoDB" id="79115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="148" mass="17314" checksum="FD55044980C360DC" modified="2022-08-03" version="1">MSSTIATAEDPTMRCKYSSKPCREPRALKKTGELHNFCEFHRSMANRNQRRSDQKRRHRRQLQYANMLTEQKNENDAEDAAQHTQSENPSHSGELYSYGSPMGIDEDDAMMDEDDYDYEPFQHPVSLNEEDLECLFMTVVERDVQMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD6</accession>
    <name>A0A8K1CLD6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Quinolinate synthase, chloroplastic</fullName>
            <ecNumber evidence="4">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_009361</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>iminosuccinate + dihydroxyacetone phosphate = quinolinate + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the quinolinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD6"/>
    <dbReference type="OrthoDB" id="66991at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034628">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-aspartate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10800:FF:000008">
        <property type="entry name" value="Quinolinate synthase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10800:FF:000006">
        <property type="entry name" value="Quinolinate synthase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="entry name" value="NadA-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573:SF0">
        <property type="entry name" value="QUINOLINATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="QUINOLINATE SYNTHETASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="NadA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00073351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW65194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="522" mass="56483" checksum="D2ABD6C770BF3B58" modified="2022-08-03" version="1">MRSALQFSRSLSRASRSALSARAQSTAAASLAASWDRPFPSILISEKDISAQGSFAEAQAAYLKPDMHVVKELDALLHKKKMGIVAHFYMDPELQGILSSLSWPHTFIADSLAMGEAAAKMAKKGIQSVAVLGVDFMSESVRANLDSNGFEHIPVYRLAEQKIGCSLAEAAEKQAYVAYLQKAAKTPNSLHVVYINTSLRSKAFAHDIIPTITCTSSNVVQTVLQSFAQVPDLNVWYGPDTYMGENLEQMFQHIAQLPDEQIQKIHPAHNRQTIADLLTRFDYFKEGNCVVHHMFGDKVTQRVREDYGDAYYTAHFEVPGEMFTLAMEAQNAGRGVVGSTSNILNFIKAKTEEAVAKGSSERLRFVLGTEAGMITAIVRGVQETLRSASDGGAKPEVEIIFPVAADAVATEGEELVPGVAGGEGCSTAGGCATCPFMRMNDIDALFAVAESVAEDATTAQDPMANFHPQKYSELISGHSISSVGVHPILHMKSFMEGSQLSPALVQDVQSRRAGMGCPEARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMQ3</accession>
    <name>A0A8K1CMQ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMQ3"/>
    <dbReference type="OrthoDB" id="64243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="922" mass="104020" checksum="890BCA59E1A4592F" modified="2022-08-03" version="1">MATCSRCILLWLGSWALFFTNALTPVIVVACFELGYGNRLGLAKWFPLTKQRLVDFAERDYIGGIVEVPPHLVGFSPMRFWTTHPLSRDSPAVLAAMFPVFFTFVIIILYAPLRKFYRSLKPPRRHSYRVQSGAPMKSGKSGGSMMHLNKSFFTVFELATGAELQNRVGLVSDYDSCVYIKGLRYASADGIYSNGFVIANGRWLIKTSNILTIIVMIVVKRDTESVAMTTATDFTDVEEIATNGTPTHKRPINVARSSRSVKVGRCPTPWQIWHIIRRLGGIVAAVFYVHTIISSALWSIRTLLGEIRPSDNFGINEAELILGYVGTTTIDQSPFVLSVLGDDTTPRSNAFYLQSATSVSTQRCTGIVKFNDWLYSNEFLRANWNELATQTSYNITFFRNVEVIAPVIDCTFNPLTTGDATLARVYYLVRTKTDPKDVFIVMVSMSTQDYSLPERYQQGAAGLVVVTALRDMRVTMADSDYHFVLALEYPFEGPDYSVYEFMGMTEDAMLYLDNVPSDPSQTHRKRVYTAKRSGFYINTEKSRANVNNLRWKLFTDPKLALSRWQWAGCTYWLNVWGWTRLIYFVFAAETIFNILVLVLVSYRNLRRGKIWIGDAFVPISRSVMLQGVAAFLIWVLEGFWRPFMMTLSDGSALGGGVGVSMLTYIVHGDLITLYISLAGLLGTMLQERIDPGLVVLLFEIGFYYRIEIAHWFPTTKAIVVDFAVRDYFKGMVEIPVELQGLSPFGFWTTHHLMREVDALFCNLFPVFITFVVIIVYAPLRKLYRHKFPAHPAGYSSRMTTNSTQGDGGMRSAFTIFELATGAELQNRVGVVADYDNCVYIKGMRYATPDGIYCNGFVIANGKWLIRTADIFSITIILGTGLRLRDVYIYEVKDHKVSQTARLVYPGTMSLKDLLVLNTTVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMT5</accession>
    <name>A0A8K1CMT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMT5"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="57"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="323" mass="35609" checksum="57F8D21E32333A24" modified="2022-08-03" version="1">MATKQLAEELRGYARSERHLRQFQEWTDAITQVLPINVVEPGSTAPLANEKDKAVTQELFSRLRTKTLGGIVLFSPAMASTQTFLHETFRPAAPAGVVCYTAHQLQGKGRGTNTWVSPEGCLTFSFRSSFTDGASLPFVQYLVSLAIVKAVESVHELPSGVANPVRIKWPNDIYANNVKIGGILCQSEYQNQAFSLTTGIGINISNREPTLCLRDALSTEDKPCNVTKEEFLAAFLNVFEEMQDEFMTKGFAPFMDAYLQRWLHSEQVVQVASDDDSEAKVPAVIKGLTSTGCLLAESSGQKLELYPDGNSFDFLSGLLKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN91</accession>
    <name>A0A8K1CN91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008129</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN91"/>
    <dbReference type="OrthoDB" id="157566at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="119" mass="13204" checksum="EFFF90EA95A825CE" modified="2022-08-03" version="1">MGQCGSSQTGVSRCPEGHYCQPWNPSYYQCIPAPEDKKCPTVLPGWDFYGSDLETKYGLLPGECCDACYNSRECRVFTFVNYNSDGKSACYLKSAINEQRVAPDAVSGYKNRFAVIGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNH4</accession>
    <name>A0A8K1CNH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rotatin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428850at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044782">
        <property type="term" value="P:cilium organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030791">
        <property type="entry name" value="Rotatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691:SF1">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1947" mass="215307" checksum="ACA774D15D449100" modified="2022-08-03" version="1">MGVATTEEPRHIDVSGVVASLVVKLEHALPRIRGRALANLRFKVREGLVDVATQPPHVVEALARALLRCLDDDTELEVNALHILQELLLHKECNEEARLAFRRQLQRHGAAAVFQRGASNAQPELRSIYDSLLQTLLTTVSGSATPATVPAATSRALHMSSASVSSSSQASSVIKDEHANMASSHASLLARSSTSVELIRPHLDSLAAGGWRFPPVTLASMDEQYLFEFEVKMRLRTTIPELVEMTDTFRRELLRDFPPELFLDRPAIVLCLLQLVQQPLLPPNGDPKELSFGANYFDEVSSESYTWKPSTQATAVHVSALKAIEALLSALRHTFQVSLNPIYHVYTPGREEYDIYLAPLHDNKRFLYPRVVGAGGDEAPTDGFSLGGVAYQLIVGLLPLLQVEYYPRLHLIEIIRQAIDLLPEQGLRGRSDDTAVHPLDVERVSVIFQGLAGVCDQLDDKNTENPEKFATLELLSWRIVEVTHKLLEMNPPSVYKPDATHRDPTSGFIAIPSALWRFVLKTVALKVSLSGDESGAKENEILACLEQFDSSALTTVAAIREAQHESTRLRAFFGITKRHDSNSDNAGGVDPSNDDLELALLAVQVIPSLPEEYRITATRAVVNSIRNLLTRDHRGISPEEGSLVQHIVCSSLALAWGESPHAREFSYHVLDCLLDASDHANANDSSDSLRRQRFRGKLIHYMITSELFLQQLLIILAQGDCDSTRNGSRDVYWRWLVVLLESQHDSEPQAFIETSMVPLLQHFAYADPVAIGVPSSFRSVKRTLVHWINRIEQKATIIEKLLLICRCLLHRSSYLRKAAAAGLFDTLSHLTSPQRMEMVSQSAFRNDPFGHFDSSIDSAIRVVENELASFILPQVANSAQNTHVGSSKLLRVSKLRRLLSALKASDASVVESSLQQVELELSTASATEWSILEDAGEVDATVKLIFSGLQELHSSDSEKRKLCGPLLSVLRMVLNNSAEWRERVRRSAAHLTALLPFVFDQSTVVRAAMYFILLSLTCTVEMFASSHEESRRARVPMEMASTFGLFSERWPLYGVETCSLSILAKRSDSSRPSAHVPTQLKDQAQKLSLGEISALAWNRVVRATSYRSFLDVLYQLLAMSISSRRIRRHVIDHYAHDLIKYLQTPPTSAKDEVVLASLLSLLNVVLVDMDRSQLLEVVRLVTRSVLPLLRSGRRSKGNMHSSVLATQLVRLLLHLSESRLSDVVEALVMDSQVLSLLTETLISSATSDALLNSLSMELLLRVVRLYSSRGSLSEDQTSKIQSIIPPLLTHVCRHRVPVCDNSAVEPYLGSVLAAWQLQEGENDGYRSLVELLSLRRAMESYKAHCSRYLAISIDDTIWFRSILTPALHTIVEVARLIQKLLNQVSGLVPFLTKNTVIIPHLVELTVDLAYSLEGIQPQHIDTLQHKLHYVALEEVAKLFSILLAAQGSSSKTVVLSVQPEARLEFSRVTSALMAPSHPTRFQLSFARLVSVVMCNGFFDSSSPSPTSTPLAVVSLALNLWTIYKHAAETQPMTPVVLTEAANQDEVSMQNVERAAIALQVVLARSPAARQEMVRRRCVQTLVSSIRNSFVAMRMSGGFGTKSNRQHEAFQLELCRAVELHCQVLSGLVYDDQDGQKAASAEDLVGVLSANWALMRMAFRRGSRVMCMALRVIQNYLSGSDAAKASLASVSVKVARKGTEVEKSLLTLIVQQTFPSAAVGPTAPAIDPLWRSLGCSILKTALLNLECLLSATKNGLISKFLGLAIEKCQAKVKKPTREGASDDAEDQFLADLLGVLASVASSDEGNQVIMQARELRELVADILTLSGPSSCSQVAITGTLFLRNMTLSKFAKTHFSVWEATLDQLITTMQHQDAIILHDHLSTALWALVFDNQRAQTILSSKPAFMNGLRNLQHTWRLRSAGSDDASLEVYANIERIMQLLTTADPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNU9</accession>
    <name>A0A8K1CNU9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNU9"/>
    <dbReference type="OrthoDB" id="77471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="535"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="769"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="859"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="905" mass="94674" checksum="1597F787507A6AC9" modified="2022-08-03" version="1">MSKREYLLQKGLQLKALNEAVEGTGAFAGGKQAREVAKYRELCPPGTEDSQIVQLLAQTKGDAQRTENAISELWEDYRGSGQDEWATVEKKGKKKEPSFLRRDGPKNSYRQSQKPQFSDEQTADADTPERSGGRGFGSTRGRGAPAARGGRGGGRGRGRGGITRGGSRVQNGETDEDAEGENGEESAVEQAPRKEGGVKQAETQPAVATPPPVIPHLTGAWTKKPSFVQQAKPKPAQPPAPTKPVEKPASAPAPTSTPASATPAAPASSTPSETAAPVVKEAPKVASPKKSPAPVSPKKVASPAPEAKKAVEKVASPKAEKKLESPSISAWGSLDVSTSSIGEWPSAEKKTTQTPNAWARGSPILSSVVATESTTTVSAVTPTSPKEAQGSAGASPKYLKLGRWDTGASANLSLQFGSFSLNGVEHVESTSPRGWASTTVTTTTSTSKTETQSAWGTVSPKKKTPLSPTRATESESHDTTRKQASTTSAPPGLSVESGRVTPKSGQSPRTFAPSAPSPAALPKPDEVKRSTPTRSQGAFQSSSQGGSKIGSGSTYGSDFSSKSSSLYQSSYGQYSMGIGGGAGQSSTPKGSNNRSGAATAAAVQSPSHGAQPAQQQQQQQKATQQTQQRDAQQQQQQQQQGQAHGQQQNVPPHHQAGPPGYHPHYAPPPPPGMAMAYNPYNYASYYQGYGYYQNPQYAQYSPRTQYPPRGSMPYGVEGPMPGYSNPPVGFQDQHLLAHQHDYPGAIPQGFGEISGAYLQQPGHHHHLHQQSGPQSHSKGSSQMSSSQQQRSGSGMQGYQNASGSSSREHGASAPPVPNPSAGGGGGAAAAGSYGQHYGWASYGAQPMGAWGHMMPQGYQQNPSQHQHPGSHQQSYRQYGGNNSQSGNSGNESSSGTGGHAHAWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPA5</accession>
    <name>A0A8K1CPA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPA5"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="41"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="254"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="35121" checksum="AB77F8021B7D9C52" modified="2022-08-03" version="1">MALAKRRRDGSENAQVQKAAEEADKKQKVEIAGGSGYVNKQRVLVFSSRGITTRYRHLMDDFRKLLPHNKREVKLDAKDTLHVVNEIAEIKGCNTTIFLEARKRQDLYMWVSRVGTGPSVRFLVQNVHTMDELKMTGNALAGSRPILTFDKAFDESPHLQVIKKLFTQVWGTPKNHPKSKPFIDRVMSFYYADGKVWCRNYQIADEADSKKVEQAALHKGEDLVQLIEIGPRFVLTPIRIFDGSFGGQTLYQNPRYVSPNETRRDHHMDKRDRYVSRKNAEVSRSARAEDRQLPEDQFADVFAGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPG9</accession>
    <name>A0A8K1CPG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase II subunit RPB9-like zinc ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003773</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPG9"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase II subunit RPB9-like zinc ribbon" evidence="7">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="128" mass="14670" checksum="5C06E8251C46F5C8" modified="2022-08-03" version="1">MAAAGMRFCKECNNMLYPSQDRDARRLAFRCRNCGQAEEVEENCIYVNELVKDTRVQLDVLPADVIEDPTLQRDYDVVCPNCANNGAVFIRSQDGVKQSTLQLIWVCLNRDCQVDDEGNRLPSYRWMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPT3</accession>
    <name>A0A8K1CPT3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPT3"/>
    <dbReference type="OrthoDB" id="101030at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="647" mass="72434" checksum="1B06E88BBA0E5C68" modified="2022-08-03" version="1">MAHLRPHYQQLIDCLQLPPFPREGEVAWLEFQFPHNLTRAKMLKLREALLLTSALGLMEGMRPFWYGELAHTARLYEVETLPSHIDLRPYYQFDMPTVATQLDWDSSMCHLFGYEGLSESFEKQLQSLDTLNLVQMTVVEATEVTPSGIFIQFDFTAPPDLPLQDQVHYLQTVKKLVVEVKKHGAVAAHTHHRRPRFELESIGLSLERLSLTPESVQLIEEILASDVPVKRLVPPSKDASSPSNWRKPWASLLMTACGHPQATTKITHPVGDLEISVPTVSGVMFQALCSVVVHATMLKKLSIENTKHEATDTKWRWLLYALFSKASSTSVEIAGKQFSRLIPANGPVDAQSVINAAFPHTQLLMDSTALHDVDFGTVILGKGTEIHLSFDSSDTFVVEEEEGQTFQVIRDVASLDTLDILVPGYGHGVVNRSAVLQRQQGEEPPNSSSVKHIYLTDSEEDQNCVVLLPCIGARLESLRVFACGLGDEFLQLVFAICPNLKSIELAMLSLTTCHPITNALKAKKSQLTSIRMREWDVEDESSFAALLAMLGDLNSLAARRLKKFVINDRGSVDDTFKDASAKMLARVVHRNKCLKHVEAYMTPKVHRVYQKALAEIREEEDIKEDEDEDVGDRCVVVEAEDEDSIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQL8</accession>
    <name>A0A8K1CQL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQL8"/>
    <dbReference type="OrthoDB" id="124121at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052391">
        <property type="entry name" value="E3_Ligase-Neurotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133">
        <property type="entry name" value="ANKYRIN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133:SF40">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="47136" checksum="2818ED4026E92A03" modified="2022-08-03" version="1">MDGAALHALYRAIDDGDLAAIRQFFVRLKATRASSQQRRFEWHSSAKTLRWSLFFTTIRRNHLNVLGWVLSPVGCEEIDDTAYNMVTQIARTAIKMKRQDNTDVLELILQSTLLMEVLTPTERQSALQFILNDACLHGHVNLIQLAVAHGAAVNGRFDECPSLQHCVSGKNIECVEKLVECGVFGVRVSAFVRSESYEMTVALVKNEVDLRGEPHRWSPLHEAVYGDKYDVVKALLTVGNVDVNASDEYGITPLMIAVRWPFRSESSHSLVLILVKHGANPGQQCHSGETALHFAVRGDEVGEMNREGAAFLAKQDPGIINIPDNNGTTPLLALTRKYTASAHAYNAEDLDVLMSYGADPHIRDNQGESAHDWFLEDENGRLYMQSRRCFFSSETDAEVRSRHKDLGHLVTWTKLHASKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQU2</accession>
    <name>A0A8K1CQU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubby C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TUB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQU2"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.90.10">
        <property type="entry name" value="Tubby Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000007">
        <property type="entry name" value="Tubby_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517:SF7">
        <property type="entry name" value="PROTEIN KING TUBBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517">
        <property type="entry name" value="TUBBY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01167">
        <property type="entry name" value="Tub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01573">
        <property type="entry name" value="SUPERTUBBY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubby C-terminal" evidence="3">
        <location>
            <begin position="189"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="51113" checksum="400D83AB3B171BB6" modified="2022-08-03" version="1">MYASRRSSVSRREEAASQVNRKSFRNDEENQVTPFHLDDGTDDNEEIRRRRYSSSSSSSSSGFERQRNARYSRGRVQKKFSVKHSHRESDENEWEKASSASSGKRHDSYSDNSSDSEDEPAPPKQQQTRTATPDSPRKPNRQKTQQSDDDEEDEDSDVEEPATPNIVIAPVRSVDLSNLGALSKLAVYPGSEAQLLQGHIVRVKTLLHSQYHFFINNQLILMAEKQLKARTSNYYVFDMTRAAGGLSTKLTKKSGNYIGKLRSNFSKKKNVLIGNQSRKTELGAIVFNGNVNNSEPRRLVVVLPPLNPKRQELEGVAIGGDDAFSMLIQRYKVLKHSRADSPHTHRLYHELQVFENKQPVFENGFYRLNFNGRVSMPSVKNFQLVKSNVNSSSIQSSSPPASAASSRTTTPREDDPEVFLQFGKVDDKKFHLDFRAPITPIQAFAVALAQFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR62</accession>
    <name>A0A8K1CR62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prefoldin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR62"/>
    <dbReference type="OrthoDB" id="248120at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000003">
        <property type="entry name" value="Prefoldin subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14364" checksum="CF1F87D09311EA3A" modified="2022-08-03" version="1">MSLKEQVDAEMARYRTLQEEVQVLATQRQQYAQQASENTMVQQELDLLGDDAKVFKLIGPVLLKQDASEAKTNVKKRLEFINNELEKANKKIEQKEKDAVEIRKNIAQMQMEMQKQAAAAARSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRR0</accession>
    <name>A0A8K1CRR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012234</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRR0"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="484"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1007" mass="112801" checksum="D3A8487F605DE502" modified="2022-08-03" version="1">MERKFQLVDAAYCFLTRHKATPSIRNVLQMASSLGGEAITQTELREMAAIAPELLQLRALQPKQVQHRDDLFCDRPKAPDELEVMSFPSLPQISQRVVAKRLKIFTEALKHRSNGDPELTAEPPAAAEQSPQPQASEPPVAVDEDPINSSMWVQLLKGMDIYRNQIVHIESRPSRPAQYRSLESLTLPSAVVGALEKRGIKQLYSHQLESIQATMKGENVVLSTSTASGKSLAFNIPTLSWLLEDPQSTFLYFFPTKALAQDQIKSLRQFLHATGLPEHYCATFDGDTPMKARSMLIRKTQIFLTNPDIMHLSILPKHTQWKRVLANLKLVVVDEAHVYRGVFGAHVANVFRRFFRLCALYGSNPRVICCSATVRNPKGHFRMLIPRLPPQDSENAPPNFAFFHERPLCVITQDGASAGEKIFCIWNPKAANDTGAVTKTADPKPNVSTPRKRKRLIEEVMSTDATNDENKSEISSHSTSSIFQSAKIFARLVEEEIHTILFCKGRKLSELVLMSTHSVLGERAETRALIKRVHSYRGGYSPEDRRRIERQLFQGDLLGVIATNALELGIDIGEIDCSMHLGLPTSVASLWQQAGRAGRKHTQQSLALIVCFDSPLDQHFARHGRDLFTMEPEAVTLNPNNSKIVAPHLLCAAHEHALYDRRSGLEYVDRFIFGSDVDASADADSEPASVPQLIRDMLSRQHLYRQSNGDGGGYRVHSCAPKEIRSLSLRCISDIVYKVLTDDAEHVLLDEIPGERVFFQVYPTAVYLHQGREYIITRLDVDQKIAFARRCHQPLTYFTSCRDWTEVDVVKVQERTKWIGSAPEPVFVCLGQVSVNTSVFGSTLLEKKTMRVLHTNEFSLPSMQGFGNALWLEVPNELRVRVESASFVWSGALHGVGHLLLAVVPLFVLCDAGDIDSEHYNPFERRSRPNRITIYEHREGGSGIVEEIVRSLPAILFKAWTIADECSCIVGCPSCIHSAQCTEYNNVLDKRGSLIVLEHLVEAITSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRX9</accession>
    <name>A0A8K1CRX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_006189</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="431720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000009">
        <property type="entry name" value="Voltage-dependent T-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF62">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN 60E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="12" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5 12" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="557"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="639"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="676"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="816"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="855"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="946"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1090"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1173"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1205"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1241"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1287"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1399"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="113"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="518"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="628"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="815"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="1171"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="domain" description="Voltage-dependent L-type calcium channel IQ-associated" evidence="16">
        <location>
            <begin position="1443"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="707"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1063"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW68721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1634" mass="186571" checksum="DE71D604A1784969" modified="2022-08-03" version="1">MATQPRRRPSVTLSSATVASKALQAFSAHGNSRKLGHMSVANLLRRPSPPDLIQTMINSSPGCYQGDDGSTDICERYNFYAHGKRFLFAPCSLGVFDESNRFRQAIIWCITWKRFDQFILLLIFANSIILSLADYSKVDKNGDLDSSTSIRNAIVNRADRIFTIFFSIECSMKIIAMGLIGERGAYLMDPWNWLDFVVVFFGILAVIPGIPNVSVLRTFRVLRPLRSLNAVAGMKKLVSALLKSIPELLTVVAFLIFLFFLYGVIGVQLWSGVLHPRCRLTPYPVRLDPNVTYTGLQTYQEKILADYSLFTCNGDDGQPIPVREDATHDTSPWRTPRMCYWPIADEQIAQTCALSGTSYRQCPTGQTCGSDFDFYGNFRFTHPDKDIMLYVLHGATYNADMSWGYANFDHIGAAALSIFQCITREGWSDIMYMLQDAGYGLSSVFFFVSFIIFGSFFMLNLTLAVIWENFSEASLEEAEEKKLRLASQALKSKHKISQPHFLTKSPFRTIIGRIIQHWLFSWFRTALILLNTIILSLDQYPEDSNLEEVVEIINFGLMLAFCAEIILKVIGLGWKAWSEDRYNWRSSAKLKNRVVFWSSIRQTLRTIQTRAVLAIAPEAAFHDVQHNPRNMEAVYVPRANFDTILWSMVTVFQILTGENWNVVMYDGWRSAGWSAVLYFISLIVFGNFIVLNLFLAILLGNFEESSEDEKREEREREELRKRARVAPATGNWRSEREDRTQYSGSHDEDHRPKASFNMTTSGRSRRGSNAVFDERVASTFHRQSVNAPKKVANRSLLILTVHNPVRKFCIKVISHPHFDSISLALIAISTISLAIDNPLNSPNSTFVTLLSWADSILTILFVGEVLLKIVATGFVLDENAYLRNNWNVMDFVITSLATFSLFEGSSRFKFVKTLRTFRALRPLRMIQRNPGLKLVVSSLIASIPQILNVIMVCVLVFLIFSIVAVNNLKGRLYSCRGEAFDALSGTQQDLITYPRLWDDMRKTEHTWFNFSSAEILQSITNQEDLTSRLMCELLGAQWGNTISQSFDNVLRGCQTFFEMTTTEGWVTIMLAGVDATEVDMQPIPNYREGWAFFFIAFILVGTFFVMQLFVGVVIENFNKMKEKLDGTYLLSAAQREWLIINECMLNLRPIRKMKTPQNHFRRKMFRLARNPNFEIGIAGCIVLNTVFMAMHYFGEEDLYRKTIEFSNYVFALIFTCEAAIKITGLGHYYWKDAWNRFDFVIVLGSFIGLLYQWAGGSSVGALATSFRGFRVGRLFRLIQSAPSLRQLFNTLLITLPSLVNIGGLLFLVFFIYAAMGVQLFAKVKFRDLITPTTNFQTIERAMVTLIRCATGERWNDVMYELASTEDCVEDPTYDPTMCGFNNSPNCVALNGCGSPVAFIYLYSFTLLVTFILLNIFIAVVLEGFANEKDRMDGILLPHHYESFVNTWSLFDPEATGFIDWYVLPNFLEALDPPMGFDKSTKPSTKEIMTFVELLDLPVFRKNKVFFNDVARRIGKFVVDETSDEPLKPLPSALNLEQRWRKYLQARKVKRQDHTVFRVNQFNAAVFLHSAVKAQIFRDDLKRKVEDYSNLIYEKVPEPRAMTMSPVIEDVEYAMAHPFEDYLSLKDSMNDFNHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS34</accession>
    <name>A0A8K1CS34_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_012414</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS34"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="896"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1033"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW67298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1075" mass="117818" checksum="47696F2F7EF013DC" modified="2022-08-03" version="1">MTSLSQAVESPREVYIAMPSPAPEKHKGDAASQDDGRYWQAYVQVDELVLKHAESGIATANLEQSHGLASTSIERLRAVYGFNRLSPPERVPDYILFLRQFLDLFMVLLNVAGVLSLITYLLDTSVPLNLYLALVLFGIVLFTCIMTFLQQRSTSKVMDSFKNMLPPKCTVVRDGVSQLIPAEELVVGDLVWIRNGDKVPADLRILLCNNLKVENSSLTGESELVSLRATAHDESVAPLECKNVAFNGSLCFDGSALGLVLSIGDNTVIGRIAKLATSTAQRETNMQREVKAFVRFISILAIGMAAVLFGVGVARTKADDVLNTFVNGFLVIIVANVPQGLPATVTSLLTITATRMAARNIFVKRLDCVETLGSITLVATDKTGTLTKNVMTVTDTWSGRAFQRQHTVDHLVIDTDDDVDYLNGKTVAATLFRGAALCNRAATDQSDSSTLHSGTALLRTARKRQAGPGTSSTAVSVRDRESSFRVRRDFVAKRKYTGNPSDIALLRFADLQFSAETARAEYPLVFEIPFNSTNKWHLVIVPSTGEKTTSQSFDVFMKGAPEVIITRCNTYLTMSGDEQPLDESFKQDFTKAYELFGSHGRRVIAVATRRFTSSSTASFSADEKNFPVSDLCFVGMIAIMDPPRDDVPEAILKCKEAGVKVFMVTGDHPLTARAIAHEIGLLDETARVLELLSPTSAKAMVPMNWNAYDAAVVHGAILDHLAPEQLDTILRMNQVVFARTTPQHKLMIVNASQALGECVGVTGDGVNDAPALKQADVGVAMGKNGSDVAREASDIVLMDDDFSSIVRGIEQGRVIYDNLKKTIAYTLTHLWPEIASVAINLAFGMPSGMTSLQILSIDLGTELGPAISLAYERAELDIMQRPPRDMSKDRLMSSPLLLYAYLVAGMINLLGCVLAYSSAFWRHGISLNDVFMSVDVYWQDGAPLLCTTDDVCYDDKEQQAIVAQAGSSWYIALVFCQFFHVWMCKTRRVSFFQHGISNNPTMIYGVLMSLSLAIILVYVPGVQGFMGSATVDYVPWLIGFGTGMLTWLYSESYKYAARRDLSSEKESVLVRHLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS52</accession>
    <name>A0A8K1CS52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Purple acid phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006042</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS52"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488151" description="Purple acid phosphatase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="158"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="463"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="529" mass="57848" checksum="398514D0CB1F8790" modified="2022-08-03" version="1">MLSWRGLVAAALLARLGLASHQFHLSLVGNSVVTAGNVDYMLDWVTPSGVDSSVLIYGSSATSLNKEIEARGAGAVEEDDASVECWSALLHDLKPGQTIYYAIKGDTEDDAEPKSFTVPKGDITWAVFGDLAAPMQKQAAGVSLPALKEECDKGVYQGIVNLGDLGYELVKKNGQNYMEELEHITSKVPMLATIGNHEHEHAMSPEFALQNFQRRFASYGLGAGTVSGSASPEFFSYNSGLIHFVFINTEIYGNEAYFALQEDGSWKPDEKERREMAALQADWLAYDLSRVNREETPYVVVCTHRPPFKTPLSLSTAGNKFVKEILPLLSEYNVDLYLAGHEHTYLYFEESEYLNYRVPPIIISGSSGNNEYIREIEEIKMEGFEQKVVIPKYGYGYLTATKKALKWKWGSTGSDSSHTPKPEMWTLEDEQTIPRRDIPSAAEKVGKPIKEPEAVQVAWGVAGSGASSGSTAGDADYLDKDSPMGTVAASNGTNNKKSPTPTPSASSAKSLMSSLLGIQFVVIITWFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS81</accession>
    <name>A0A8K1CS81_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS81"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="83"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="664" mass="73762" checksum="B2DABAFA4D2A96EA" modified="2022-08-03" version="1">MGVNTSTELPMSAIDFETYQGLRYTQEVPNSRESNRGPIYVTKPIHVGQNMLTMYDNLLTGVGIENGTRRLYGMRKIVNGQPREYEWMTYNQAFAHVEAIAAGLTKFAGLKRNDMVGIFSKNRVEWCLSSHACDRMTYTLVPLYDTLGVDAVPFIVNHTELTTIIYASELLSVVLECKDACPTLRYLIQYEDVTDEQRRLAGEKGLKLMSFAELEALGKSHPLPADPPMPEDIATICYTSGTTGNPKGVVLSHFNMAMLGAMTRDRVPFHKDVVHISYLPLPHVFERAIMTSVVFLGAAAGFYQGEVLTLMDDIAELKPTIFVSVPRLYNRVYDKITQGVAVAGGLKKMMFDKAYEAKKTGIADGRKTHALWDTLVFSKIRKVLGGRIDTMVSGSAPLSAEVKEFMTIAFGCDFIEGYGLSETAAVIAAASRDMPLGPHVGVPLSNLLVRLEDVPEMGYTSNDKPRPRGEIICKGPNVFSGYYKEPDKTAEAIDQDGWFHTGDIGCWNADGTLSIIDRKKNIFKLSQGEYVAAEKIENIYAKSKYVAQIFVYGDSFQSVLVAVAVPDPEVAEAWGVSKGRSKEDSTVAKLVYDTEFQKEVLNDMTRVGKEAQLRGFEFVKKVHFHPDAFSVDAGLITPTFKLKRPQLKTYFQKEIDAMYAAVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSW2</accession>
    <name>A0A8K1CSW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007708</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSW2"/>
    <dbReference type="OrthoDB" id="167531at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471947" description="G-protein coupled receptors family 3 profile domain-containing protein" evidence="11">
        <location>
            <begin position="20"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="596"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="632"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="666"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="705"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="755"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="791"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="12">
        <location>
            <begin position="596"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="859"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="881"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="894" mass="98800" checksum="B5DC8930CCB7C042" modified="2022-08-03" version="1">MWFPILVIAWTLQASSGAARPIVGPNRYLGTCLTAEWVASMEATLKINASDRDTKGRRMFPHLHAALTYPRHYVDDPRTMSPDAYSASCTQADTVFYGVGSEVDPAKGTMVKAGSANGSLVIELNAWTSDSTHSLASLVFGIIASEVYGYPVSMYATSSSLSLTERMSTAPAGICTPTHVNLEVWPGKEALLRVYANESSAIGPIGADFWRDYALFDDMIEAVSYEAFASDPTRFPTKPVCEDNKLGCQNHCAKSNACKLRESGGGKCLVVVLMSPTWDPGYLQAAMSNLNIPAYFCFLGYSLAINYILDSQQAKRPILFYHYEPDLFHFNNAGLFQRVLLPRPIPERVQLNTGTFGEKGYGEPTTNPVDVDFPAAKLAKYAASLLQNNQPIGGLVSKFAVQDLDMNFLLRKYIDATNDVNGIEPNFRAACDWVQNHYSTWSEWLDRLPLCTMDDHMQYQVAGCNGVMTGTDPAESMRVISFKWARPDPSDSSKPYNCDGGLDKLPTAIQTSRTCEWIEANPSKWKLWIQHQPECQPVLYKYNVTACDPSADRTVKYWWLLPDPQDASKSLECTGGDVLPPQIKIPCEYMPTSAPAFVTIAVLGNILMAILVVAIWFVIYHRDKPIVKRSQFELLVVMIIGGIIVCISALLYAGKPSNFLCGARPFFISTGFTTIFGALIVKSLRVYRVFMKTALKRVTVTVAMMFKIFAIFVCVDLLILSVWFIVDFPHPTITNEHDSSFGGNVDRITCKSSSFLFTAVLMFWKAIVLFMGIYLSFLIRRVSADFQESTWIFASSVAVLLACLVILPLAYMVQLSASAFYMFLACSLLLATAGVMGMMLIPKMFRLNQISKSSKYASTDTSAAGGDHTHIHSGATVAPHESSTTTVRRQSSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTK1</accession>
    <name>A0A8K1CTK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">acylphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTK1"/>
    <dbReference type="OrthoDB" id="10248766at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="3">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="121" mass="13463" checksum="13B164FE770AF09B" modified="2022-08-03" version="1">MEGDDEVSASVMRFFRVRGKVQNVMFRQTVIRAMIKRGLEGGATNDKADKTLVHMTLVGDNHIVQELVDAIASGKALNDWGAKATEVKEVEETHGKQLAKHQVTTGNVHARNWNPNCTMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTQ9</accession>
    <name>A0A8K1CTQ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_005978</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTQ9"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000006">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042469">
        <property type="entry name" value="HECTD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="11">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="15989" checksum="49769AFAB67DF847" modified="2022-08-03" version="1">MICGSPEIDVDLLQLCTEYSKCSETDDHIVWFWQVLREFSHEERSAFLRFVWGRSRLPVNEKAFPQFFKLQSFSKQREGRSVDEYLPVSHTCFFSVEMPTYSSQAVLREKLLYAIYNCQAIDGDGDSVAANRLGWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU15</accession>
    <name>A0A8K1CU15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU15"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="55568" checksum="30EDC1CBD79C43B9" modified="2022-08-03" version="1">MKFPLPRNPFPPVQLTPHQERDLELLADQLLQRTVDEYDHFLHIQNREVDKTKWKHVKTRENMSVYKSFGDMSNDPHMLSHDAMMTPRGSRLSSSSVSGVRLLGVGSIVGNFADLMYAATTLDDGDMKIKSSYIPDECVDWRLLKVLKHGTEEDPFLCHTIKWVVKQAPGATSVIVRPRDMIILDCNGLIQMPTGERLGYMMHQSIEIPEWGELEGIVRCQVSACYLFRIQNANSVEVYMRSLIDAGGNVTDFISAVSSANALIATWKLPWGGQNKKLSWMLKQASAKRADANTAVLGARKVSKSKEPCPLCQKSVSMLRSVAQCELCFKQVCSRCLTVRKISHIRRSGELIQKPTAFCKQCVTQASQLDSTDIIRIDCIPKGYNNRSEATTMASISDSAYDPYRPSSVDSEAWTMTPMSRPDVWETGSVQIESSDDWERDQMQRANRAPSEPSGFSQQQQPLWMQMNQLRLAAEQAYQLTKQNENAMHQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVV5</accession>
    <name>A0A8K1CVV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001791</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVV5"/>
    <dbReference type="OrthoDB" id="57605at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="88" mass="9928" checksum="65D95DEC1F352A0E" modified="2022-08-03" version="1">MAVKAVAGPSTHLAKWWLKHAKEQGRITRHLSPKEIHPVKSLIESIPYKTARKIKENAAVLVPSAVLLVGTVKWGVQANDEHHREHWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVW5</accession>
    <name>A0A8K1CVW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001805</name>
        <name evidence="6" type="ORF">Poli38472_001806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVW5"/>
    <dbReference type="OrthoDB" id="161460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272192" description="Chitin-binding type-4 domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="25782" checksum="C183644FDD39DB62" modified="2022-08-03" version="1">MKITAVLVAAAAAAPAIVNAHGGMVVPVPRAIRTMGLSIDSTFGHPINVRAGYTNGKGGNCLDFTPDGNLQSIPVGTSKIQMRTNDGANHIGPCTMYLVSPTDKNKKQQIGQLNDCMRSLHPAAGAKGDPPIPAEMTINVPENPEVCGKDHCVLEFYWEATHLQPHELFNNCADVKIGGGGGGAPAPAPAPAPAPGPAPAPAPAPAPAPAPGPAAAGAGGYVYSGPARPDSASMTTWCNQNCPGFCPGDICKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CX25</accession>
    <name>A0A8K1CX25_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphatidate cytidylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_001974</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CX25"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46382">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46382:SF1">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW69818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="52323" checksum="8D3EFBB546EA0F10" modified="2022-08-03" version="1">MAAVSTSPFPDATPDILHDAARHSQDSITDDTWTITLGPWKLQLSNGAQRFLSALVLAPLITFFLWSSPVFATTTVCAVVAAVSCYEYAWIAHRIHLRFIVTLEKYEEANTVVHPSCSSTGSGVSYQSNEPTYPVEMTPPTALERSQGQPPVGEVMEEEVVAFLNKSCAVTPVAARFFCGREWLVAIIVSVFGTIISSFLFRLVSSTDAFYTVNFGGYRMYYAVISSFATWMCACLTPDWKYGTLLVFQQELFTGLTLYSMRCPINDFSCDNIIHPAMFLMFGIVGILVLRLLTSTGPIDYVVHIMLDILGFFYVIGTLFFIVSFVDVDRKATYRKLIIALLYVVWAADSGAYFVGQVFDYFNYKNYHPLASHISPRKDYEGTLIAVFVGMGTMFLASDVLSINGTIAEKLFFSATAVIVGRIGDLFQSLLKRAALVKHSGILIPGHGGVLDRIDALMFASIVFSRYFGAIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBL8</accession>
    <name>A0A8K1FBL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SANT and BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBL8"/>
    <dbReference type="OrthoDB" id="550012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045902">
        <property type="entry name" value="SANBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021777">
        <property type="entry name" value="SANBR_BTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20946">
        <property type="entry name" value="SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20946:SF0">
        <property type="entry name" value="SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11822">
        <property type="entry name" value="BTB_SANBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT and BTB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="413" mass="47600" checksum="3567A06CCD677469" modified="2022-08-03" version="1">MARNVLIHVFDEYRKATKDFVCPREVLLDKMKYFRAYLNQANEHDEIDISVHCDVEIFEWLVEYMNQRDVDTRPKITLENIASILVSSEFLQMDVLVEECVAFVTSRMQEFLQLRVDFGCLSDTTITKLAERCTTEQLQRLQDPKDKILSKLQRKKLELLLRELQEAKCTLCCCENCELLYLSSEESQLHCSQGVRQLSAHGELVASHRPKTGWVPDEWLKTVIQDKNVSWGAAYWYVWASTQYMQCDTCQRYCSLLEFRDCFYHPGQIVGVGAEAKYSCCGARIFLGGETDGSGCKSREHKLAPSTPATIQKSVQILNASWSAITSCSKVVRPPPYGRSCLYIDMSIVCPAPTVEQSAELDQVLKKPWPMNADAASPRRRRQWQTMRLQEQDRIRIQVLTKRLLQLRQNLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDB1</accession>
    <name>A0A8K1FDB1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDB1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000031">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="250" mass="27440" checksum="A966EC9D336E323B" modified="2022-08-03" version="1">MSRRYDGRTTTFSPEGRLFQVEYAMAAIDNAGSAVGILAKDGVVIAAEKKTVSKLLAPSKTSEKTIKLDDHLLCAVAGLTADANILINYARLTAQRYELAYQEKQPCEQLVQALCNYKQAYTQFGGQRPFGVSFLFAGWDRHHGFQLYHSDPSGNYGGWKATAIGANNRAAKSLLKNEYDENLNVSDALKFAVKVMSKTMDSTSLSAEKLEFTTVTRDENGKVVHRQLTQAETDALLKEVEAEKASAGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD0</accession>
    <name>A0A8K1FDD0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010324</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD0"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="54780" checksum="962E507978630023" modified="2022-08-03" version="1">MAGERTPLVNAGGPSRALARRKTLIRIAIGVLVGTAVGAVLVAISGGFSGSNKSVLPSSLPNTTQYDWFCNEPSFEASYIKLANKKDDYYFYWFAASRNDPSSDPLVLWLTGGPGGSSMLAMLTENGPCMVKPDVSTERNVYSWSNNANVIWLDQPTGVGFSYDGGSDDDDYTELDVGANIYAFLQGFLDKHPEFEGRDFYITGESYGGHYVPGASHYIWQQNKASGDKRINLQGIAIGNGLTNPLVQYKYNQDMVNNQYNISLLTEEQAAQMKTDSEECIELTKLCQSEPKNGTICPEAQGCWEMKLIEPFSGANRNMYDIRKECSPENPVSCGLDYSYLGDFFASEGVSEYFNFTKQQWIESNQVVNKHFVSSGDWSFSYHEYVADLLNDGLRVLIYAGDADLMCNWIGNRAWTLELDWKNKEGFNAAEEHAFVAVDPFVDGASKVDAGVARQYKNFAFIRLYESGHMVPTDQPAVSWVMIDKFFNDGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDL1</accession>
    <name>A0A8K1FDL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDL1"/>
    <dbReference type="OrthoDB" id="14527at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757:SF0">
        <property type="entry name" value="SLL0781 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16755" checksum="8961E0DBB1013DF3" modified="2022-08-03" version="1">MKVRFAEDAWNTRDPARVASAYTPESVWRNRSEFINGRAEIEAFLARKWKKEAEYRLIKELFAFQDNHIAVRFAYEWLDQGNNQWYRAYGNENWVFDDHGYMAKRYASINDVPIQDSERKFHWPQGRRPIEHPGLSELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDX4</accession>
    <name>A0A8K1FDX4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AGC/PKA protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDX4"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="48"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="303"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="39522" checksum="C836F10C1E1A7D08" modified="2022-08-03" version="1">MATTAVASPVPAATSTPAVASSAGTGSATLSTSGKNPKFVGHLDGTQFDMGVTLGTGSFGRVRFATHKTTTTYWAIKILKKAEIIRLQQVEHMLSEKSILLCLDHPFIVNLAGTFQDTKYLYMVLEYVIGGEFFTHLRKAGRFDNNTARFYAAQVVSIFEYLHSQDFIYRDLKPENLLLDSEGYIKITDFGFAKRVAFKTYTLCGTPEYIAPEVLLNKGHGKGVDWWTLGILLYEMLAGQPPFCDDDPMGIYQQILSGKLNFPRFFDRNAKALIKRLLTADLTKRYGCLKNGVEDIKKHKFFSGVNWDDLLARKGAAPIIPKVGTANDTSNFDPYPDSCEDAIVPVYNGKDPFADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFE3</accession>
    <name>A0A8K1FFE3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007049</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFE3"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03796">
        <property type="entry name" value="GT4_PIG-A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000188">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000093">
        <property type="entry name" value="UDP-GlcNAc:PI a1-6 GlcNAc-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039507">
        <property type="entry name" value="PIG-A/GPI3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="10">
        <location>
            <begin position="75"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="9">
        <location>
            <begin position="231"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="53054" checksum="81192B42253227B3" modified="2022-08-03" version="1">MSVDLVRSSMESDERPTYRIAMCCDFFYPRLGGVEMHLWSLAQCLLRLGHKVIILTHAVDAPASPSSTKRPLPRQRVGVRWMTNGLKVYYLPITPIVDNVTYPTFVGNFGLFRSICIRERIQIVHGHQATSTFMHECLIQAKTMGFLRTIYTDHSLFGFADAASVHLNKVMKFSLSTIDHAICVSHTCKENLVLRASLSPDMISTIPNAVDASKFTPPTTEPSASSSTINVVIISRLVYRKGIDLVGRAIQIVCAATPNVNFIIGGDGPKRLMLEEMREKHRLHDRVHLYGAVPHANVRDVLCQGHIFLNSSLTESFCIAILEAAACGLFVVSTRVGGVPEVLPPDMIEFAAETTPEALAQAVLDALPRAAKVNRQDFHDRVAKMYNWNDIARRTEDVYEKVMTRPAMPLLHRLQLYYGIGPIAGMFACVIAAVLHLYLCVLEAWKPAGEIEEALEWPRSSASHAEDDDVDAEDDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFI0</accession>
    <name>A0A8K1FFI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000129">
        <property type="protein sequence ID" value="TMW57677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFI0"/>
    <dbReference type="OrthoDB" id="61834at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="177" mass="20589" checksum="4062E09B52D14E41" modified="2022-08-03" version="1">MSASFSLNWIKTRTAKVAIKDVQELLRTLVEALATTGCDVGQFRLYDTDGDEIVTESESQKILDSMILTQKAVLAELFATHVDQMPKKHMKLLDIAVNETNWKEKLPEKVRCVFYFAPKEDEEDKTVCWEAFKESQEAELPELNDIVRVYAKGYYDDRHLFFERKQRSVVFESRVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG61</accession>
    <name>A0A8K1FG61_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG61"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.730.10:FF:000011">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="329" mass="36239" checksum="9483047F43515131" modified="2022-08-03" version="1">MCWSRRVPSHQSVAIARVLTTVVGLSWILSWPSVNAIDYTGGWLPGPRKTQCVDICASSVQEESACVKSNTASCRQRGPGEYDYLVFEQLFVPQFCRDLRHGVDPTVSHRNVNPFPMGIQCNASRVASVLTIHGLWPNNRDSYPACCAVSTSIPNRPFHAAAFAEHQSSLLEQMSTQWIDATQPSTYDTLCEIYNHEFQKHGLCFAAFGDDYEKAAVHYFQAALQITSQLEAATRKIQDWAKGLQPQTSLGELEALYSMRVQVLCSNVDGEATENALSAIRTCYEKPGAQDTPFKSMDCPVATTAGAFKPCRPDTPVTLLGYSPLMSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGP1</accession>
    <name>A0A8K1FGP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGP1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF3">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460067" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="38"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="47579" checksum="E72B97ED0528525F" modified="2022-08-03" version="1">MPRLTQVLSAITLALGVSTTQGMFRFDCFNNLVVDRVDPIINPGTEGGHVHIISGGNAFSKDAKDLTKSTCTSCPIGADLSAYWTPALYVKYKNGTGYGRVKSNQIVYYQPRGDKTEKIYALPPGLKMVAGDVTLKAYNETDIKQRAVTWVCLNFANPQKEGPIIPDGVHCPDGLRGQVNFPMCWDGKNLDSEDHKSHMAYAEGLDGGKCPPSHPKKVIKVFFEMFYHVKEWDSEWVGDKHPFTLSNGDRTGYSFHGDFFGGWDEEVLQRATDECRDKNYFNSGECPPLAPTFSDKPPAQRCTLQPEIKEEVDSVKELPGMNMPMPLPSAGPAPAPGTSVAPSAAPTTAPGTSVAPSTAPSAAPGTSAAPSKAPTNPSSAPGTKTPKPSRTRHTRSPKPTTPAPSKEVGGDADGDYDEDDDSEVGNDASASPSTLPSKCKAKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGV8</accession>
    <name>A0A8K1FGV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGV8"/>
    <dbReference type="OrthoDB" id="870at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09252">
        <property type="entry name" value="AP-3_Mu3_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14837">
        <property type="entry name" value="AP3_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="176"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="47957" checksum="20FC06AFFF24CD2C" modified="2022-08-03" version="1">MIQSMFIITTTGEVIIEKHWRGLTSRNVCDFFMEEVNKYREREDVPPVIVTSKYYLVSVFRDDLFLLAVVTNEIAPLFVIEFLHRVLAVFRDYFGTFDENSMKDNFSTVYQLLEEMLDNGYPLTTEPNALKAMVAPPSTANRIAAMVSGKSRVSNTLPDGALSSIPWRKSGVKYTQNEIYFDIVEEVDAILDTNGQIISCEVSGVIHSNSRLSGVPDLTMVFTDPSVIDDCSFHPCVRYSRYERERVVSFVPPDGQFELMQYRVQVKQFIPPVYCHPQVSYSEKNGTGTLDLQIVTRGMPTLASNSKKTLQVEDITVDVTFPKSVRTVDVNTESGTCIFDESSKTVKWNLGKMNKKGTSPSLRGSIVLHQNAGIPDEKPIVLVGFKVPMSTVSGLNVETLLITNEKYKPYKGVRTLTKAGRFQIRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIE7</accession>
    <name>A0A8K1FIE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-pyruvoyltetrahydropterin synthase</fullName>
            <ecNumber evidence="4">4.2.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.12" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIE7"/>
    <dbReference type="OrthoDB" id="14045at2759"/>
    <dbReference type="UniPathway" id="UPA00849">
        <property type="reaction ID" value="UER00819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="entry name" value="6-pyruvoyl tetrahydropterin synthase/QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589:SF7">
        <property type="entry name" value="6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="36601" checksum="37F5634E5CA304A5" modified="2022-08-03" version="1">MLQPLDGKVEGSLAVEQPAPVTSDAESETPQKKRRKMASTNANAPVVRELTVDQKAIVKMNVTREATTDGVVKCCYCEKEITSKNVDRWASHLRGCVKTPEEVKMQIQPFRPMQTPNIHSPGLGVGNVMSPTTTIANANAGMTPTGHLVTGLPTHAAPMPTSTSTGYNEVFKVHVSKDYMKFNAAHFIAYKGFREKLHGHNYRVAVTITGVVGHDGYVVDFGEIKKISRVICKDLNESFLVPMNSDVLKITFDGTNVHILTEDMAKFSFPKADCSLLPIVHSSAEELAIYISNQIVDAFTVVALVERGVRKLEVSISEAHMQMASYERTILPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIQ8</accession>
    <name>A0A8K1FIQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIQ8"/>
    <dbReference type="OrthoDB" id="5065855at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="4"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="26028" checksum="71B8798103946474" modified="2022-08-03" version="1">MVRPSLSEDMLKCLRPREWLNDEVISYFIDKYLPQHDAVLSLDCQFFALIKLMQETKGHSYNSYLEYADIAGSVDWQKHRIFQFPVCMNGHWSTLAVENPFELVGPTVFYHMDSIAGYHKSDDVVRVVLKFIACEKLRYTRRKHSGKFQVERISTIPQQDNDYDCGLYVINHMRRISNAYRENPQLNGKKTIRSLCSGFTKQSCSQFRSNLIELFKSDDLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIY0</accession>
    <name>A0A8K1FIY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIY0"/>
    <dbReference type="OrthoDB" id="60283at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="79065" checksum="59AE73AEA68E9BB9" modified="2022-08-03" version="1">MNASYMEMVIKDDDLRGLKMVYKLHKQGISREHPQFGFRKPMRLAAEYGRLDMLKWLGEQEERGEWLEDRWLLDAAIKSCSLDVVQWVHSVYTGKDQFVLLCKPLDLVAPQGALELLQWVLATFPKAQLTTNAMDGAAANGHLEMVKYLHSEWKEGYVSAESLEYAKEEDLLEMIQLFEQYNVDGWTTILMDHAAAVGCLESVRYLHSHRTEGCTTRAMDEAAKGGHLDVVKFLHENRSEGSLLKYFSNFVDAIPVDLIEEAVCNGHWYITKFLLSTTDQLDAMSDRSFSKTVEIASLYGDIDMVELLLSANYRFKPSNAHGFINTSILGNIDLLELLEKARQQGGDLWERLIYDGMDTEPFAGTKMKWRSVQLAVTAYYGHVELAHWLYDRRYGHFKSAHLAQCAASDEVDMARTILSFEPSAQVTNDAIAAAAKRGNVRLFKLLYQFWEVKESRRPLIDYAAGGGSYDLVKFIHENCPKAVCTWRAIDLAVRSDQLDIVRYLHEKRTEGCSVNAMGIDACKDYLTTLQFLHTHRHEGCTTAAMDWAAAHGNLSVVKFLHENRSEGCTSAAMDEAAEREYFHVVQYLHTNRTEGCTTSAMDSVARHGSFRVLNWLNENRDEGCSTKAMDGAALTSQLTIMRPGMVKFLHKNRQEGYHETVLDKAVQLDPEDESLVQQYLRPVELKDNYASSLFTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL8</accession>
    <name>A0A8K1FJL8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10611273at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434588" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1390" mass="151915" checksum="90CC961B494CC108" modified="2022-08-03" version="1">MGKQSAVTWLVGLWALTVTLSVVAQEPVAAGATPVAVAPVSAPEAAQATALATAIGVIAPPVAAPAPVTATATTPAAPVPSESPAAPATVPSVPAPSGNAVVPATVSTAPSGNADGPVPAVPVVAPVSASVVADGGIGPDWTPINSATELGPDFFFDVQEKAPIDGKTFFALCTIRDGLASPGCYAKKEKSMAESLTLSAAQGLKLTFPGNNEVLISTADGLYWKINKDARSIEFTDLASAAKFQIYTNAKKDTVFLKVEEFFVRAHQNKDGDWITLSPMLVARSFFRSWKFTKTITKENIDASRHAIDLPMIQARRKATTTSRAWVAYDLAVAVLLKRDFKTLILENANGWDIAMAVDHATTLMTTTPLLEEYQKLYPSLGKGLPDDFRLFDWTSAVKYTADKSPWQSAIHIAQKLPHSETNPIRDNFRTLAFASLYVANFQASQQLVPFHTPIVLEGYFAASCNLAWLAPDRKNLTLAQLVEYTAMPNFGNNALINVHYPINGIEQYWFTKLLSPEVKSLNYSATTIFPEIALLKHLNASWVSEHSTIGEGIARFALRQFDSWLKEYELGQIIDYFKDPAAKEVVDALKAVCKPNMRISACTIPQMHAIAQKSDSFLSARTDPLAVVELKSISTTDLQKYNTLIKRDSTLGDLVDQIAKTKTEAASLTTDFFSQVAEKMEDATLATMMKTNEQVRADAVATFEQVKTSAAFSMNLFQNDASTQLQIAKDKFNAAIAVRPKYLENLEALATKAMKQAEMRSYFSIAKSVLSFGDIMQTAVAQPYSAMNSLSGFQNGLMDMNQKLMQWNSAESLKKNLQNAIPQLESIAKVITDAAPALEKLRNLVVPLVAMKDISNVGNMTDDFQEEYNKVKRLDLTIQISQVRVMFAQTSTQMCTIIQLPAYPPCVDILKHSTEYFGNLQESIAASNEALASLGGVLDSAYDVTAASDAHDSLTTDGDRDLEGIKQIAGENKDEQDKAKFRARKQIDTDQAYFTLSALQGQATYLQKMYQLCARIGYANGGMVPDSCSRQVMAFKRVRLTELNSLLSYKPDTRRQTENSAVYIPTVPQFPNDTGYIDLGELMNGHTVKFQLPQNYTWLQRFGWVNEQSDFKNSVIYLKQFKLMLPPRYTDFNEEVMITIKSNGKADLGPALTLGRYYTLPASKYVVSYGTKQCTSDAVANPYATCGAPMKELCYQTQGESESFPDLIPTLFSEFKISAYYANAKGSKEGFAYRSLASPLYLRAVITTEIAEVQTATQASRRLRRSTPSSQHTEKRRHLREMEVAAAEAAATRCCPMGSYAMVWTKAPSPQCIPCPAGSVSQLGGVFCAYTYSNNAAKSSTAAASTENLEEEEEEDTEPEDDTSEEETEEAIPSAKATPSASDEDLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJX3</accession>
    <name>A0A8K1FJX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="1999"/>
            <end position="2096"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="6">
        <location>
            <begin position="3430"/>
            <end position="3504"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="3637"/>
            <end position="3666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1373"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2103"/>
            <end position="2132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3333"/>
            <end position="3409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3614"/>
            <end position="3645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3657"/>
            <end position="3683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2358"/>
            <end position="2392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="3041"/>
            <end position="3089"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="3282"/>
            <end position="3326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2115"/>
            <end position="2132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="3357"/>
            <end position="3367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="3368"/>
            <end position="3383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="3394"/>
            <end position="3405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3683" mass="423752" checksum="697FD45A8023C5B3" modified="2022-08-03" version="1">MLVLPSTAEKKKENARRRPASSEASPPRKTTRLVEDLLNTKAEMLTLPLLKSPTHQVARDKALLQQMLLDCKTKSPQKEVELASHGSGNQQSGRDRCETDATRIPDVVFFMENSCVGLLSVDLSDWACLCRENSSVLRQIATSLSSNCVELKLRGLTAVSSPKALIELFQHCQNVKQLDLSCFRGIAKAGFAAIARQCPSLEALSLAESDALTDSLLHAIVSALPHLKTLTLNDCHRLTDAGILAAVKKLPHLKRLSVDHCVAISESAMLTVIQAYGARCRTLSVRGLARLTDKVVQALFITQPRGLETLSVSDCTQLSDDGLEFLCTVPSYFGTRVTTAYHQLHHFDLSGCVRLTSLACTWIAASCPFLRTLRLARCIAIFDKGLNALSTLQHLEELDLSGCTRLTDAAMSKFFVAGNTPKPLSNLSLVGCRSFGSLTISAIASSCAKTLQTLDTSDISECAPSVWTTLVKSCRRMETWRCRGQPGITRGVLTHLAGANRVLRILDLRNCINIDDLALYPLLVIRSLQELLLSGNRQITSKGIRSLPSNIKRLELSAMPQLDDEACRVLVERTGNALELLTLSGSSGISSSSIETILRRCRYLRALNVSQCSQITVQSLGRALQADTQRRTQQNEPDRYGVELIDDDDRQFFGIAAVDDEAARNARSREVALQEAQRREAAAISIQVRFRSRARVLWKRQQLEEQQQREYDAAVTIQRIARGFLDRRRYVILRALLRKAAVYLQYRWRRRREQRRVRKAMSYWTNQLVLKMFSRWKDHVLGLKADREHAHRMRRAAKALGFWSTRTLARVFQAWRTFATSRTIKAKKALAFWKCQSLPRVFEAWYQLVRQRSQHKQRLVVVFMQCVELETHNSTRQLEHVAKANRSALRVVIKRWRSFVHDQKLFLLQSSLSLLTGHVLPWAFREWRATARELRLRRDKHRTLLRKMLNHQLYRVWLAWLDFRDAQRAKRRALLRFTASTQTKCFLRWKAAHQANKRLQQVSARVVARFLNRQAVDAIATWYSFTQDAVETRQRQRRALAFLFNTTLIRTFQAWVGYTMFVKNLRARWKARLAQAGLHFTFTQWVDYLRLRRELHCHATRLQAFWRGQLSRRQTEDAYFYRIWATVLIQTAWRQRLARMMLRIIDRKARLREYLRAERERDAMDQEEAHMRAYDHMIEQIIMLQRRWRGVVARQLFREVRRARYILRKQQEIEMQEIIRAEARRKQLEREQLKRAKELAAVEIQRHVRGFLTRQWYKTQQDHLHQTRCALRVQAVYRSRMSRRRTAALRRSYLTRMEVLSRRAVEGKLLRTMGAQTRATQRPLRGLLSFFGLDLATFLLDIRAVFREVHEDFQSLKAFFDVVRTRVQTAQEQQKQHAVENGAAPSSPTKSRWSRQFFKRSESAKKLLADMEMIVNTTANEQEAQAQLVERGDAVRIILRGHPRCGETAFVLSLTEDIAQVKLDVDGALEFFPLMLPAAKMEAAKPVFHKIPSLTFHAAALHNGKINWKWRLELEAYAQRIQDDAKRFNAARLIQCAGRVYLARLRYQQELERQGVHAARRQQALLRVLSTFRAANTRITNILVHLHLVRPSNLPRELDDEPLMIHKIVNRFQRQMLRRQEINQAYLRLVPEPFKGHGAFQGGIMPVSPTRIIDKLIHYPLLWLTKITRLPMARLLEMQGNHELAQFIGGAAFVRTFEERHIDARAHWFDQLVGCRFCAHCEGWAVVHGVFEKRVLSTDRTYTQENRIKRLHQSTKKKVPHGWGVAHFLTGRVGNKQRSWLERDSIEAQFKSLTLVRKMQQEEHEGRVATQILARQGTWNTLRSKEGPRGFAKRHAELSTLEEKTKAFYARFQRELALRIREEVKIFEEEARVNALIAVEKQELETQGRALQELQQLVPDVIAEVRLMTSNKTPLEFLSVGAEIRVEYDDEEWYVCQIQGLDIYDSYTADIWYVEDQRKETIKLVEASVLEAKQFQMNETRKRPKTVAEITADATRRARSTEIPFRKWTAGKAVEIAWDAPLDHGAAVSAYKLEWKDEDGSAIQGESVVTTTQTTLWPIPEHCETTLRVRVAAQNIKGMGLASVYMALPPELTDVSYRTAVPIAPPPRDTAPEEGQEREQMGREDTLSKENQRDLTCTQCQTTLATPAEVDEHVARMHAVPLICPFRSCQQVCASERALRYHIWRATITKPTQEELQSELFMEIFDLSKQYCFRKPRRHGLKGAARRLIAEQKYEGEDDDDAMAVEEEVYLENKYQEARTTWFAAARGIHERLVQEKRRDEAREIASRYTPPSPLYGVDYQDAEVDIARREAVIATIGMLQEDLDAFRLETATKMDQLRHEEKELVEYIALKTKRMKTSEEEWQKQSLKREKKKAQKNLDQVQATLQQLIATSTQRIEEMTTEIERLTVIQKAFIPFTHQVIKLQRLGTVIQATHAKSNAILTQHRVILAHYQEDLRILLVRMIEQVAQLDAWDAMIAARRKQLEALTTELHDLQLQHRAEIESFRLKRDQGDERFDLTKLRQQQAAIWKRREEEEQALLALARGKKPTRGELARSKAAAQAQPIEAMLFAEIAMKRRSLHIANHDLQMHEKFIKGKSADVEYLKDDEPAIEEKAGEASQPAGEASVQEAVLAEAKQDEEDDVAALLAPKKKTKKMKRVLEELPHSYVRLECEFVDGRIHGDVRIEYNDGSVYEGPWVEDVSYDKPVDLEPHKTRHIGKHWGKFTYHDGTVWEGEDVDNYFSPFTATGQQFQVTTPQGHQYRGQVRMGLYHGFGTLSMQYTFSKGEYIGEWCEGKRQGYGIERFDNGELYEGYWALDVYHGHGEIVYDDGSRFDGMFRYGKWQGDGVRTLASGDRILGIFTEGFLNGPGVMEFADKRHYVGEFLHTRRHGFGALAFPNGDRYEGPFHHDEMHGEGRFITKAPEGSGTTEPLVRLGKWVHGERVAWLSKASTQLATSTFIQYFGVLENVSGEIELNLLPPRFKTPYAVMVASQLPTLPEGVDSSDPFVQSIVRMLAKTQNVVVGAGLLEKTANELATTQQALGGLQGECEEIRNDVERAERECRAQQRAVNDLEAELDDKTAKEQEMQVKVETFWKKDTYGHEKKYKLAVDELHACEVMDWYKLRRASLDNVYMSLLEAFATLLHFTTNFYLNDKPYKPTREDIMMLLSSNEENVHLGDKEGLIHRYDVKALYVLPLFDVYSFAEGTRNQMLHGITSVIHHPRLGPNNFRLHQISPAFVAVCHWVRAAFFYAKKAIEIAPVVQRVMNQLIVLEHLKTTLDTERKTLTQRQQEAHEARTRLEEKRHDVDEVEHQVKALQKVMTDIEALDKAEHTPLTKAHIKKPQSYRPASAGLPPPPCDDEEEDEENEESKAAKAEREKKKAEEAAAAAQVNRRQVFEEDHAEGTDAKQTQRLKKEQVLAQILTNEELAQDFELLKKEVKKVLDRSGGKVPVDEFPQRFEEVMLKALDPMHFGIKKMRTLLLLMEDVCTIVEPMKEGEIETVQFPIEPDDEPMLPRQPFFCRLCPGMSFATPSELSYHERTKWHYWNLLAKQEGRPPTKYTIAANYWSEAYDSSDNTICYYNKMTGEVVKSEDPPMEMQANDLVLELLSDAPLETMEQQETETQDALADSESQLQDADPWEEVADEAGDVYFYNRLTGESSWTRPEEDQANDEPAGNGRLDSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK29</accession>
    <name>A0A8K1FK29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008223</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK29"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="81"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="4">
        <location>
            <begin position="234"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39671" checksum="1B76730AECAF4A8F" modified="2022-08-03" version="1">MRAPDLCDAAPVIIPSRRGHTVLVVELFVKASPSASFRKFQSSSEIGEPASESFFQTDTMFRTRQIAFKFVAKEQSEGVGARVRRSIGSHKLRNLDPFLMLDEFNVGLPGGFPDHPHRGFETVTYVLPTSTGHMLHEDFLGNKGDLRPGDLQWMTPGSGIVHAEMPATTDPAHGLQLWINLPKARKTMPPKYQEVNRESVPHVFNDDKTVEAIVFAGEVFGQKGPIETEAPVTYIHFIMKKDSKLEYRVPEGHNTFVYTLKGDGVCAGQEVTAHEAIVMEVEGEGVEFSTSSDEGVEFIVMSGQPLNEPVVQYGPFVMTTKEEIHQTIYDYQSGKNGFENAPVWESEIKERRYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKJ1</accession>
    <name>A0A8K1FKJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012286</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKJ1"/>
    <dbReference type="OrthoDB" id="3564374at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050663">
        <property type="entry name" value="Ankyrin-SOCS_Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193:SF121">
        <property type="entry name" value="ADA2A-CONTAINING COMPLEX COMPONENT 3, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="249"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="46701" checksum="461A20ACBB18754F" modified="2022-08-03" version="1">MDEATQGALFHAAVDGDLAAVERFFIQSSTALTVDHVNTAHRQARERAFKDQGDVVVITTEPHELQTAGSWYFYNPSDSFELVRGCLFELLIENDRLHVLEWFFSAAACKIIEDTMRGLIVRVSLAAINWDSMEAIEILLDSHLFVEVLSSQERKLALQDILDHAFGRQCVELVRLLVAHGVDINSFCTRTAGFRSYVVHHTVKFVEELTRSGLLSIGYESLGSRLAFQSAGTALAIIKSGVEMQSEPDGWSPLHIAVNMDSVEIAEVILIHSAVDVNTTGTDLFFGSGSERSGVTPPMVASPKVAPLLLAYGAGARMRDSEGKTVLHYVTEDPDHKQAFKLFLQLVPELINTPDKDGTTPLLLMVCHPTQYNTESLEILLESGADPYAESDQGVSPYQWLMENAQGRTYVESHSRFFPSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKL7</accession>
    <name>A0A8K1FKL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein eL24-related N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKL7"/>
    <dbReference type="OrthoDB" id="1727108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="17054" checksum="139E373673359DF4" modified="2022-08-03" version="1">MVIKTETCSFSEGRIYPGHGSRYIRRDGTVYTFLNAKSKSLFMQRKKPTKIVWTLGWRRMNKKIKVEEIARRRTRKTAKVQRAIVGVSADDIRKKRNQKPQVRAAAREAALKEAKDRSKAKKTGKVEGVKNVAKGSAGPRAQKKTGNRGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC9</accession>
    <name>A0A8K1FLC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC9"/>
    <dbReference type="OrthoDB" id="68212at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="56575" checksum="682047603E101F9F" modified="2022-08-03" version="1">MVNSYAQVSTPTPNDATPPSTQPRWKRLVFGVPGIVAGAIIGILIGYGLQEADASAEVVSWVGIPGTLFIRAVKCLVAPLVFSSLVVGMADMLAVGKASSIGWRTAAVYTLTTILASCQGLLWVVIFRPMFSNTSAEVADTTPQMAFQCDKPGYFLSHANDTVQCVFDSSYNETSEFSSSSIFFVNDIKGSFAMSSKGYAELSLTDTLQAQLFSIVPDNITQAFADASLLSIIMFAIPFGVAIALLPKEMTIIANVFREFVEIFMKMIGWVISCTPFAVISLLASSVASQEDLGVLVSDVGVFVGVVLLALAVHTFLFYPLVLRMFVPGNPFAWIQQMIRAQVFALGCASSMATLPITMDCVDKTAKVSPTLYRFVLSLGATINMDGSALGYPIAIVFMAEAAGLGHLIGGVEYFLIILISTVGAIGSAPVPSAAIVMTMTIWTSIFPSTPLPSTFAFIVATDWLLDRFQTAVNVTGDTVVCRIVAHQVGETLDAHERTSMSSATDGLANSNSELKETIRQSHLKEDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLP1</accession>
    <name>A0A8K1FLP1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLP1"/>
    <dbReference type="OrthoDB" id="77293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000120">
        <property type="term" value="C:RNA polymerase I transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039495">
        <property type="entry name" value="TAF1A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14929">
        <property type="entry name" value="TAF1_subA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="880" mass="100892" checksum="E674BF63A25C4D3C" modified="2022-08-03" version="1">MVKSSSTSPLLVGVPPPPQTSDPQLHALLNGVYSRFGQWKVSGDITTRSVVRWLRTALEHLLDQLLGARDYAGAAQVLSVVYHRFTLIPSRCIQASLEILRRKPGQHKDELLQFYQTALQSKGLDELMVKKEILMLHIASGDYYDAYHFFKAEVQQLSIQQDAHLLGVFGMLCYWLIFIESDELREKFVFDQSPQDDDDDFRDDDEYGGSLRPRKRKRGEKSSGPQGPHEILRTRFSFKTPIGVHILYQDSIGAFNRAVSLCPESAVFLEYYIQLLTMVGEVGRACDHLENFYHSNPSNPHAARMLTQFLERHFPLSISNQATAYARWVENDPMCRLALEKVLDFGETHVIPASTFVHVLASVLDHHGSDVQLAQSRQITCRLWKQFAQAIVACETGDEAQFAMIEDVRLSRLWWCEAFFCRPRSAAAVEAIANKYPEMIEALVFKAVCGYRLFGTRGAGVAKALKEAKLEEIHTKLIKSHIPESMPISGNMAELQVPSHRDTPDWVSVHIPVMNRSVINKHTSHAQPPKIMVTRRDGEAQVDLQLIAALEEAVASELGESSQHLNGATRKRSFTQMQDIRDEQEERAAVPIFVSVLEELIFMSKGWQSKVFSFRHIQTQLQLRLRGVNAVMPSLLEVRAVIRYFQDRWTMNEALYGFPGLLHRYDSFLARFIRQHAKDTNFWRTNLTAPYVTEAMRQMKLHVSRSQTFFPRRDHVEIVLRVKAASCARTRRLLLREYMLAMRDLAYHVDFVTTEDLVATAASLAKMKGHFDFLSTEDLTRWAETVLVRRYSAVVAHLGFKHREFLLGKEMENSSDDPNILLRAIKRRFHITKATLNQMKAFVWVRQWLRQHPFTWRELLEGEQEPVDGSSRPPVTVIMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMW2</accession>
    <name>A0A8K1FMW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_006169</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMW2"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="178"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW68701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="26406" checksum="0E3E9BFE7A560F2A" modified="2022-08-03" version="1">MFVMINASDNPWMVALLVFVQVIVPLLQSNAADDDGDVFMSILLMLLLAVPMLFFFKYYGVIRAMFLMRGQHPNLTWREFIREANARELRRREASASAAAQAAAAPSAEEAFDRIMHTIQAMPMEEFMTPDELRETSIHELKDRLKRRDVDYAGCVERNELVDLLVTFRGGPSNNDTCCICCEEYQSGDIMRLLRRCKHEFHLECLDKWAFTSVNAERKPVCPLCNQSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN37</accession>
    <name>A0A8K1FN37_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008119</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN37"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="276" mass="30689" checksum="421C85130668E69D" modified="2022-08-03" version="1">MAAIATKTLRSGAAIPVIGLGVFQSEPGAETYNAVLSGLQVGHRHIDTAQFYRNEADVGKAIVDSGIPHDQVFVTSKIVSTVWNYDDVVKAVKESVGRIGGGYIDLYLLHAPFDSATRADAWRALEDMQAKGLLRDIGVSNYGEGYLKKLAETWRVKPAVNQIELHPWLTRTDTVQYCESQGIHLEAYSPLAQAKRINDPVLTRIAEEVNATPAQVLIAWILAKDFITLPKSVKELRQQENLDSYKVKLSVDQVQRLDALDEYYVATWDRIKDHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPL3</accession>
    <name>A0A8K1FPL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit</fullName>
            <shortName evidence="8">Oligosaccharyl transferase 48 kDa subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008385</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPL3"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035486855" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit" evidence="8">
        <location>
            <begin position="23"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="319"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="451" mass="51021" checksum="02C9497ADD63EBCD" modified="2022-08-03" version="1">MSTMLMRFVTLLLALLLAVTDAFRTAVLLESADVQQTHAKFFQLLTKRGHELSFHVNDPELKLEEYGVRSFDNLVIFSPQKKLGNLAKTDLLNFVESGGNVLLSASAKLTKLQREFALECGVEFEKKGNLVVDHVNALADSDDIFNAVIAAKDFVQSERVVGKRLADPTNPNKKPVAFTGIGMSLEPNNILGFHALVAPFTAYSANPVKEITAKIVENDLLFGNEIGLVTAIQARNNARLVFSGSLELFSDEFFTDAYSNEEFSDAISKWAFQESGVLRMTNVHHQRADGRNPDKMLKDAQRPDLPITLYPDAEIARDSLVYRIKDNLTYSFDLHELKNGKWVPYKASDVQLEFVMLDPYVRKTLTHDNKGHFSVTFESPDAYGIFLFRVMYRRLGLSTLYSTTQVSLRPYKHDEYERFIPAAYPYYVSAFSMMAGVFVFSVLFLFYEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPM8</accession>
    <name>A0A8K1FPM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPM8"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000012">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="51115" checksum="044A873360C71F9B" modified="2022-08-03" version="1">MLGRTWRHAHAARRAFPRRQPLLTRSLSSAAQEEASVLTREYIYGALYAQDAGYFTTQAREVLHAPPQPIDFKNLWGAMDYRKVVAELYKQSREAWLTPVEVFAPHYSHALAKYMLNSPFFHKHMRIYEIGGGAGTNALHILNYLRDVAPDVYEKTTYTLIEISPVMAERQRQRVVTEHPQVCRVLNTDILTFADAHDVVNDQCFFLAMEVLDNLPHDKVAVKNGQWYETVVMAKAKTTTTEDTTLALALEEQLRAINDPLIRQTLEYFGCDLPLSVSYRVNNEFAKKVRELFGKNEMSLDAAFIPTGAMQLLNTLRVSFPRHHLIAADFDELPAPSLNAKSPIKPLHHPLSPTATSEGTLCAGNAPLVASKTTGVTEDHDTYLVQGGVADIFFATDFARLKRAYCSVLNRKPEEVSVVKSASFLKEFGDVSKTKTLTGYNPLIQDYSNTSFILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQD3</accession>
    <name>A0A8K1FQD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CDP-alcohol phosphatidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQD3"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF37">
        <property type="entry name" value="BB IN A BOXCAR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015665">
        <property type="entry name" value="CHOPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="42603" checksum="ED926B27EFCE3056" modified="2022-08-03" version="1">MTMLSKKALEGIASYKYKAGSYTFIDNQLNVFWTAAVELLPTWMAPNLVTMVGTCAMLFTTIVQLFVSPHLSEPAPFWVYLLSAVGLFFYQTMDALDGKQARRTGASSPLGQLFDHGCDAFCTIINVLSAAATVQLGSEVLTYVAISSVSITFYMAQWEEYHTGVMSCGNGWYGVTEGQLTLVAVHLLTAVVGPAFWTIVLPVPFVSITPAHVLVMALIGSNIILVSGNVLNVIRTPLEAMSAEEAGAKHRAKPVAMFQLVPISILVVLGYFWVSGPNVADYKAYPLLFLFPYGIAFVFFSTRMIVSHMCKVPFTPQLRVLIPFGLLILNTYGPTLGLFPKPLLRPLLATVLYGLGITCIYLHYVVHVVYDISCYLNIYVFKIKMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQD4</accession>
    <name>A0A8K1FQD4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQD4"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="36021" checksum="7A34D906FB20CAAF" modified="2022-08-03" version="1">MSSTAMTIPATFRGYVAQGFGPFEDNIILRSDLTQAPLQPTQVRIKMQAVATNPVDHAVVEMGHIFHPNAPTTEKPLRLGFEGVGTIVEVGKDVADFKVGDEVVTLSDFDCSGTFAEYHAVDATHLALKPKKVTLHQAAGLPLAGMTSYQALLSAKLTAGDRILIIGGSSAVGAVAIQIARALGASFVATTASTRNLEFVKTFGPDQIIDYTQEKWGDVLAPHSIDVIYDCNMEPESWAGDAQRVLKKNTGRFVTADPNYKPNESPIGATCTTVYATHNQEQLEFLLKLASEGKLHVPINSVHSFEELLEVLTFQKSKKAQGKLILDIVSTKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS17</accession>
    <name>A0A8K1FS17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GB1/RHD3-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001728</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS17"/>
    <dbReference type="OrthoDB" id="2135133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001470">
        <property type="entry name" value="Interferon-induced guanylate-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1000.10">
        <property type="entry name" value="Guanylate-binding protein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003191">
        <property type="entry name" value="Guanylate-bd/ATL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036543">
        <property type="entry name" value="Guanylate-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10751">
        <property type="entry name" value="GUANYLATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02841">
        <property type="entry name" value="GBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48340">
        <property type="entry name" value="Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GB1/RHD3-type G" evidence="7">
        <location>
            <begin position="60"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="566"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="665" mass="75125" checksum="F08EB6008104B5B2" modified="2022-08-03" version="1">MMRRMSMGRRGSSPTRASLSTAEQAMQDFPEEPIPLITFSENEDQLLVNEDAVNILKRIDGKVAVVAMAGLYRTGKSSMLNWLLDRQAGFRVGPTIERCTRGIWLWGHPQKRQLSNGEDIWVLMLDTEGLGGLEASQQYDARIFSLATLLCSKLIYNSQGSVDEKAIGGLSFIANLAKHIKVSADPGNRSSIASNANGGEDDVMQFHQFFPSFLWVVRDFTLELVDEDGDPISSSDYLERALADQPRIPANMERNRIRAMMKDFFRERDCVTLVRPVHDESQLQQVDRLPIENLRPEFQKQLADVKDLVYGDSLKPKTLQGKPLNGSMFAGLLHAYVDAINSGGVPVITSAWEGVTASECRKAMTNAFDAFKKMMNEVDLPVDNEELLAIFKDSEQRAVQEYRKNAIGDMAGKLEGDLLKKIEDEKASLTTRNTGLSKEMCERLLQVLYSEIIQPKLTTVSGEEGGFGDMQQFAMEWTRFRDAYLHKARGGAKLECLLTFSETKYAEAMRILLSRQEEGYEKKLRTLQGDVARVKEELGSVGGREQIYKEQIEQMQATSSQILTEKARFEAESQAQRDRIVQLESLLKDESKTKQSVEVERESMDLKLNSEAKKREEVSGELQRIKAEYEKLVKEKEKQEMELSMLNKECEELRHGSKKGCCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS66</accession>
    <name>A0A8K1FS66_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS66"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="157"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="554" mass="61307" checksum="890DB9FD44188BE9" modified="2022-08-03" version="1">MQSPRRPTRVRAKADAKKPVAPASSASRGSRKRQRPSVTHVVTKPHGSSLRKHQKPKRSGADGYTKPAAASRWQPPDSEDFIPFGATSRPSPGFPRGPKQSLTIRTSTPTLSNKKKNRKKRKLAETVGSTTTTPASSRATLIPLPKLSMFGGASSDLDAEIMAFARFVSLTDEERAFRNRIFYEIKHLILAVFPGAHVKLYGSSSSGLETFRSDLDITVGGDLRVTASLGEIPDVSSAVISDEDDSASDHVVEDSDEDEETSFSLNLAIPGASMSIGNNGGQPVRRAASAPNKSPWNPTLRREKLRQLRLLQQLLNVHRPDYRVKCLPKARIPILMVEDPQSGVSIDIGVNRESFQASDHGRTTALVTDLQSALGPMYIAVVVFLKEFLHQFELDKPFTGGLGSYRLYMMVAYIFTARVSRKAPTLTPSRMLLMFLEVFGNRQKPGFLSSTLELPVRLGNQRDVVDFASIFRLDDCVEKFAMGFDIISKFRSLGHVLYEDRLQKQREASLRRIFECIQAREQAARRQDDVATEIEDDDDSVVGFGSDEESVNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FT64</accession>
    <name>A0A8K1FT64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Intraflagellar transport protein 52</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FT64"/>
    <dbReference type="OrthoDB" id="10259368at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23683">
        <property type="entry name" value="IFT52_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039975">
        <property type="entry name" value="IFT52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055460">
        <property type="entry name" value="IFT52_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055458">
        <property type="entry name" value="IFT52_GIFT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048643">
        <property type="entry name" value="Itf52_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12969:SF7">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12969">
        <property type="entry name" value="NGD5/OSM-6/IFT52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23352">
        <property type="entry name" value="IFT52_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23355">
        <property type="entry name" value="IFT52_GIFT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21178">
        <property type="entry name" value="Itf52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IFT52 GIFT" evidence="4">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="IFT52 central" evidence="3">
        <location>
            <begin position="302"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Intraflagellar transport protein 52 C-terminal" evidence="2">
        <location>
            <begin position="393"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="55788" checksum="10E72D3CA55FE6A4" modified="2022-08-03" version="1">MDDEERGSKASEVAATAKSMVVLFDASKKEAFYPTNGMKRLARKLKATCKVDLNKDDLSKDRIKDANLIVFAGVRERFSSSEFTTLKEFMQSGGSILFMLGEGGEQAFDTNLNGWLKDFGIYINSDAVIRTVYHKYHHPKEVLISNGVVNREIARVMNEISGKKEIVQREMPGIGDKAHALEKDQKGLTFVYPYGATLNVKKPAAPILSTGFISFPVNRPVAAVWQEGGVSAPSSAVKSGRLAVFGSAHWLTDEWIEKEENGKLQEVIFRWLLKDKGIQWNPVDTEDPDLAEYNRLPDTQALSERLRSCMQESEELPKDFTRLFDSSLFKFDTSLIPEAVALYKELGVKHEPLTLIPPQFELPLPPLKPAMFPPTLREPPPPALDQFDLDEHFASESLRLAQLTNKCSDDDLEYYVKESADILGILPKLDSEKQDAKHVLEFIFHKIVNFKKLNQDAPMGAGVGVNSPTGRRLSSASGTSFTKADRDRLDDEDSKVMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Z7</accession>
    <name>A0A8K1C1Z7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Z7"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000077">
        <property type="entry name" value="L-threonine 3-dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051225">
        <property type="entry name" value="NAD(P)_epim/dehydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687:SF1">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="52"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00050613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00059023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW54970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41388" checksum="1174EC4519F495E3" modified="2022-08-03" version="1">MVFSLSRSLAASVRRHASTAARRYASTTSTTAPKRANSTYTGGFDVFEQSRVLVTGGTGQIGMELVPYLREIFGDHAIVNSDIKAISGRKEKGTFAYCDVQDRDSLARIVLENGVDTIIHLASLLSALGEKNPQLALKVNSRGIENVLEIAHQNNLRVFSPSTIAVFGPTTPKDMTPDETIMRPTTIYGITKVHLELLGEYYHEKFGVDFRSLRYPGIISSEAWPGGGTTDYAVEIFYEALNHGKYKCFLEKDACLPMMYMPDCLKASLALLQAPEEKLTQRVYNVTAVSFTPEQIAASIKKHIPNFEITYAPDFRQKIAETWPRSIDDSKAREDWDWQPDHDLDSMVEDMLVKLDEKLKKHKNRATQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2D6</accession>
    <name>A0A8K1C2D6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2D6"/>
    <dbReference type="OrthoDB" id="164869at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383:SF2">
        <property type="entry name" value="AMIDOHYDROLASE 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383">
        <property type="entry name" value="NODULIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="255" mass="29181" checksum="1CC6AE984BDF2D41" modified="2022-08-03" version="1">MQSVDAKEWGQAVRRELVSLGEHGVWELVRPPKDAHVVGCKWVFALKHNEKGEIVRFKARLVAQGFSQAFGVDYNETYSPVATLNSIRILLALCCQLGYIVHQCDVDTAFLHGKLKETIYMRVPDGVDHEPGEVCSLKRSLYGLKQASAVWYHTITEIFKQIGFTPCVSDPCIFVKRVGDDFVYISLYVDDLLIAAKQQNHIHDVKEQLRLHFKMKDLGTAKFVIGMEIEHDVDNNVMEWFGNYPRRNVDRLKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2L8</accession>
    <name>A0A8K1C2L8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2L8"/>
    <dbReference type="OrthoDB" id="2100592at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58500" checksum="709FA8F517073746" modified="2022-08-03" version="1">MSEPATAAPPVGRGRQPLLLLLLAVVGLVAWSIGTEYYTLVATAKHSIARVSSYVRPLSIDTTRNHDDIYPEEIFTKNWVDAVPVKDMTHLSSLHIACTQYKDSVIPWDLTLDGKGPEILINETDPDVYNKLRQCPDVDIYIGRGLRGFGYCEDAVAYAKFMRGRLIPKWVVEKNFFDPQMGKTGISYHELCPDTPMLFLNHYWDGLPDDPKWPAGKPMYLMPNIEMYELGASHYRRADVVICKTVVCDKYLRKWLVQEGNPTNTQVIFARHTSSNLANYARVQLGDDAIAPKNFKDPKFLHVVGGSIQKATGNVLDCWLSRPDLPPLDIYIADDLYEGAYKKRYDARIKTSLNVKVHPGRVDSVSLGKIVAEAAFFMCPSFQEGYGHYINQARAAGGLVVTPDVAPMNELITPKSGVLFQAGAVASHEQFLGGKSQHANGLRNVTGFVATFGGKEICKAVDTVIFNMTPEQRQERAERAKQQYYFDTLYFAEKMQELRVLNKGKSTFLRRETVVPPFETGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2U9</accession>
    <name>A0A8K1C2U9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013290</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13 14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000022">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056850">
        <property type="entry name" value="ARM_UBP34_24_USP9X_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25010">
        <property type="entry name" value="ARM_UBP24_USP9X-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="1934"/>
            <end position="2299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1749"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2171"/>
            <end position="2204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2498"/>
            <end position="2520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1764"/>
            <end position="1773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2930" mass="330477" checksum="D145E76B0AFC014F" modified="2022-08-03" version="1">MLYEYIGGLEVTYGNALAGGGGFHRVTTTAGSAAEVTPATYLWYKLTSNLSVETPSTPTASGQQKSKGREKEKKREAIPTAIVQLHVAGEAEDTAGGFPHVPNARNGSWCRMEKALDRQKGLFLWYYLAEWRGPESSSPTNSASSAANDGSAADIAPLKEIRVVRDLKDLPEGFEHVPIPLVSDTVDKNGNVQELRSFISFQRLDAEDLSGSRWSILKQKAGNWVDIRDLGSNRWYIGQLIHISATECRIQVSTWRKSREEVVSLTTSRNRLAKLGSYTNIQLSPAYPFCRKQGSPWNFGMKDLDAARQDFDRIFYDASQQAEYIQQALLPLVEKSLLSMYFSNELAEEVNHFHCHVLKAVVAWFLTRDSHDDNDDATVQSLLAIIRIILNGIGSCMFFYLKYGGSYSTVKSQRLVYTSYVTSPDVLSSIPSRHPGRSFYFVDNLDLFLQAGGFSLILQRVGLRDVALVEIGLFIMILQNAKPCLMITPRRKRSTSSDRRKVASTPASQMDDFFRDFLNAVLARLRRMSMEELKDEDGIMDYILGGLEMLYRDETLLGGEDAVEVGSSSVDGATEVLDVTFSEAYEVFHLDLAKKHVCCPYLAQRLLGITRLSDLITRAQRKETLQKKSSFTLKRTGSISNGLMNAVYGTSDAEPPATKWLRPRYLAEWLMASDVLEVILGDDETCHKYGLREGVHLELLKRSRSLLEYVNQSGLLTEKHITLLWRAGMNQLRSGKKTIFEVLLTLSRELSADLLDIVMVLATQVQDEDYDDLLVTFIQRIIAIASKSSLEADTGAKKSLTSFASVNPLRSRRASGTSKDAEVYSKIVGIGLSLLWNGIESWESTEGNKSSLLTHIESSFADSVNQVNRVWAGSSSSSSLAKEQQQHLHHYLSLCIESIKSGNAIERSALMVQKIVNGFGTRSGNGGSMTMSTLALARSTFQSGSTTTTTPSELLKELNSRYQLVSIVVSEVTQYMDQSRERGSSVPSIPSSNTAERFLPSAHQLAMEKRLNFLGYLVTSSDLELSYKDIERLWKCFTGELSSVEERDVFYDWLSKVLPSTEDFTQRVHADKSAFSLSTIDAIFNDLTSGSSTKSIRLDIREMTRSSFWAFERLFRCVNVAQRSLRCENGGAVKGAASILVESMDLKGVEALYDIALKAPDEGVGTDAINYIIHLHLNLGSKIVGREVWSTFMSWCLSRLQKSVHSSSTDGQEVYRLLVMMNTFLYQGSQASRNGSTADSREELTVYIRTQDGRTAPPLQYRLRKTVLVGELRDMIGRDSGYPPARVRIITEHKIKLTAQGHDRSTLEKANIFRATSSATKMRAISPVINKRPFQVEAILLAKPESDTIGHVERAVTMSANGCNEDHWDVMKAEVSKQRDSLILLQDLLSYREGICEEAWKLLKMLDYDSEMEKQTRSLNGAVEIDGSIQDKSALNDWNHLLDSASPPKLLYQLELVEKYAMYDYLTPPSPNESLVKKERSESSTGVKHNAWSASFSKLGGRKHLENFVLSINPRQVVAQGPLWMMSVSRVFKLLRHLAPIVQHHDEPSDGVGNLVHQLLEIIKCVQTLEEAEIELGLSTGSRISVVLQAKETIPDGPPVYSRPALRDLDNREDNPTEAHLVVRALQLMTEYVSVTRMEDVNQLLFDNIQRSAEVLLKCLISSRVDAVRKEAVESITGLCNHNNGALASCRRLFLTLIGEFDGPVTEPEYYRTYAKLLARSDGEIPWFNFAPASIKLCRRIKIYVPSEQRTTPDKSRSDLAPVSSGQDKGKSSQSDSLLEALLYTLLVLLRKIPREPPNALDTTNQGGSLRQSLLGTLHQDEEIIQEIYSECLFTGGEEGNDPSERSAQYYLKQPKCRSDSCRKVAFELLKELVGDNADGLRYLLLQMGKSHSLIPPPEVPGRNANAAIVTSKKKRTKSKETLQHATLERAKYVGLKNLGCTCYMNSTIQAFFMMPRVRRQILRYPSVENGVLYQLQSVFAHLEGSAKPYFNPKALTAAMKTWEGEPIDVNVQQDASEFLTSFFQQLESEMNGGMATTDGHHDDNILNAHFGGIFSNELIAEGDRYSESFEPFHVISVPVRDRKNLKESLDSWVEGERVSYTWESPRKEDSEEPPAKVTLDTHKRISIQKLPNQLIVHLKRFEFDYEAMHQTKLHDRFEFPMELDMFEYTKEGQEEARRRRSRSTSGLDDEQNDSSTNSDRSRAPEYYQYELVGTVVHMGTAHSGHYYSFLREQEGEADAEPRWYEFNDTMVTPFDPDQIPVECFGGVDDELKRRGSTGSASNSRKKNRSSFMLIYARTQPKVEDVFVPSAGRPRKKFSDVALALLFVGRMRIRTSARLQQLRARASVIAPEPIRDLIMLENRIFWRKKYLFSPDCLDFTYELVRSRIVSQKDMSSSSAQSPPSRFEPVDVRFEALQLSTKFAFGTLWQNGDVPSVLKWKKILTILYAEERRGSEWLLAILKDNETLLLDLLVTSEHADVRQLMATLLTSAITMASREASVEEDTPSTSEESRSKQRRRSSQSLPLPFEFAFVLFRLMPSLLTVPARHHREYFTVVLDFAMSGHDECAFTVVNSVVGAVVGLLTGLANTQPLLQNELKRTKSRAILKSIDLDRNVLKLLSILLRRGPPPAVDVENAVIPPNLMKNHANLTSNDHEVLTSERFITLITQRASHYTKESKSLEQIVIHLCWESRRVTEMFMDKVMHGIEVEDHDDVKPYFRTLNTLFKIKDSLASERVNDGMTKLIAVMASQQRYYKATEVSIDMLIRLAKRQTSVVVWLQANRMSCTWIEKWLSGHRGNNGYLQQRRTSLVKPNSTSPWVSFDARTEGVARSVDRAITKLLPRIRSALDPESTIETFYDSDDNPNRLVGKRVRVKWAREKWYEGEVEKFDEDSYEHHIVYDDGDRRKYRMSDKIFYVVEAASSSEVATESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C393</accession>
    <name>A0A8K1C393_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79255at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="374"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1745" mass="194654" checksum="CC128082A3CF0CF3" modified="2022-08-03" version="1">MDVSPQEDEHSRDASGTDIERFDSAWRRFRRLQRRRRALYEQMDESSKKTDRLCILADDKPWNVFGKGDPMACRRWIYQITGLHFSLLHAACAGGDKSQVESILATRSGCALARDASGRIPLHHAVVSEHHHVIQVLLLQPDARLQLYSRDNRDMTPVDLVLEKMERLARKRLPGCVPARVTAVMRQRCPRYRHLWILGDQILELMGEGGRAYMELDQRVRGDAWDAIRGCDHDRLRLVLRHASRDPDDGWTTLSHVGKTLLHEACEQPAQDLQILHCLLSEAENISLDEVDQGGCTALHYTAMRGWLEGCALILNAAKERGLDMESLLVVQDARGRTPLRASLAFSLKSDSTGIIAKFLAQHCAAALYIADRDGRLPLHCAVIYGRHSLVEELLALGADASGNGTIPSPNHCNNGEFRLKAEWAPCAQRLLRKYCRRPPPASNNECLDQVNTLHQTPGSSRACERLRKVKAGEVDHYVGSAVPLETLWLLVQSKQKSLTAHSENVTTVHKEEIRSSVHVDNGDSEHDDQEDPQRYGCRRYGGICTECASVPGTESPVLKPLSTLSDALSPLQSAIRSCRLRPTEKDRVAVVECLLFGGATVTDAAFLEALHCFHRPQLIETLIAHSGRVVPSSIVKQWCLQPKSQEEIERLTPLLRCLIADMTSDEQFSLVPVLFRTGYLSALDELARAGLVDPEVVVPSIRKSLSERNRQYPRVGVAQLCFLMRRIKNATNPSEALGLAIKETMSLLLSTTSVKTTFSHEADKLCAEAIRVLMESQPVQELFSVALVSDLIGMSTRRRMWATARELLDFLVQRHPTASSLNILVSSTTHFLREDRICDLTGAVMRVLGTMTPNAPCPDSLIVLVAALYSNDAVPLELVQQCVRIRLETSSKVGLVYLLTTFRYAHWSFVEWFVRMERVQMALWVLGQLESDSTAQQTLWKSLAGCVIACKPKNTAQWLEDLFKRVNEGAAYQDAICWIVYHRIIPTDSVESLSLVLDAVAKYLASEGVSRTELLMRWLETSRLLHQVARWNALSVLTYCLDRFPSAEFWTRQATKRDEMDQCTPVELCRVLGHVRIADKLASYCEDTSSPQQSREEASDEKTTMNYGLLRAIVALHATKTDQPPTLHVPARRPSPLDASWYTAITLDSVSFLEAYRLHDNSFCTLGGTNAALLLDHLHCAIRAGAIHALKWLLSGPSASKLLGECPPSESSALLQAAAKQTSSLYAEMTLSLLDHGVSAGRLCGDGTDVTLLHRVACFKDSTVAIQIFTRLLASEESDVNVRDGFGFTPLAYACASGQLSIACFLMQQKGIRFEAEYEGQSVFYYVLYLLPSFAWRQIVRALLTQKCNHAFLHCTSPDCACKGFESDAATDVECSFCSHPKPLHLRIPYPPWFCDQYETYSDPKTRVKSLQDTEVDSDDEDAVRQHQQMLTAPPPDENELEGTYGRLYPPDLEQILRIRYHHILEIHQIELPECPREQTENETITELARPEGTPPTPSSEGFVPIQQSYLSHPPADEVKESATMEQPYDELYKGDPAVGKTNLLATFLASETNGAPSGDAKGFSSVRKPTIGVEFGTKIIQHPNGKRIKAQIWDTAGQERYRAITSSHYRRAAGALVVYDVSNPASFENAQGHWFKELKSQADPSSTLLSCIMLVGNKVDLESPDADGFVLAPAHEEAATKLKVLEKRTSAKTGKNVRDAFEQLLIAVYDQDKAKLHRMATMRTVSLEEPKTSTTRGKQCCNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3G3</accession>
    <name>A0A8K1C3G3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010632</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3G3"/>
    <dbReference type="OrthoDB" id="75169at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF17">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="50779" checksum="C46E250A2BDFF0F3" modified="2022-08-03" version="1">MPLRLQRLTLERHDIERVIALEAASYPADEAATPDMIRFRQQHAGAFFYAAYLAEDENALVGFVNGTLTKSQELEEETMSEHEPSGTTLCIHSVVVDAAHRRKGFAGAMLKEYVRIICEQELQVKRIALIAKAYLTGFYISCGFTATRLSPVVHGKDPWFELVLDCEAARRLTVVQVDAFSSEIFDGNPAAVVVMPPAQFHKPGVEKWMLSVAKENNLSETAYLARREGGSNGIAEYDLRWFTPGCEVTLCGHATLSSAYVLFEEGHLDPSTTIHFHTLSGVLVCSQQIENGKKWIQMDFPLRDLVPVSSDISLDELARGLNLVASDIIAAKQTQTSDVLVQISTEKFAAIEPNFDLLGKVEARGIVVTSLAPPNDKGVDFQSRFFGPRVGIPEDPVTGSAHCALAGYWSEQLQKTSLYAHQACPVRGGYISITIPEDKKDRVYLKGEAIISLRGTLFTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4C3</accession>
    <name>A0A8K1C4C3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SANT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008934</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051571">
        <property type="entry name" value="N-CoR_corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992">
        <property type="entry name" value="NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992:SF39">
        <property type="entry name" value="SMRTER, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="4">
        <location>
            <begin position="787"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="4">
        <location>
            <begin position="1188"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="1191"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="1192"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="686"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="934"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1027"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1250"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1310"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1351"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1487"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1539"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1752"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1937"/>
            <end position="2030"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1877"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="654"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="934"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1257"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1567"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1590"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1607"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1649"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1672"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1980"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2007"/>
            <end position="2021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2030" mass="217685" checksum="16AD2E026209AF72" modified="2022-08-03" version="1">MADDKASAPAPKSRIINLNSSSSRTKKDIPAGLSSSPTRSSTTASPRNDGKPARPSGAPQASSTSGGSGPAARPRMPSRPGGYPGPDRGGFRQDSYFRHPGPPSRPYDGPAVPTPSEPQPKKDVVVESTLSLPEEKVVTAVVEAVKDPAPVDAVTEPRVEKTISREQENRAAVVEIPVDQAVRKRTRVEDLKNEVDKTPPAQSATAPESRVGVAERPKPNITRSSPVQKEKEPAAREELPPLPEIPLFSRAISAPVTLDDAEVSTPTKTIKRPRLGWGQGLITSSPSDEKRPRVGWGEGLVSSGSNSPSGATADNMDVDSATDLVSVDVKAEPETEATGSVAGESPAPIPIEPMSTPAIPSTESIEHGEASSSAVENHASESRTEALSVTVEDASASADDADEAMDSVDDLAVSKEVILSGIDDLDANIAQIKRQMAELQKTIHDKQAKLESPACMSSTAVADASNKSAAEAGCVTSSKQSTMQVKGDLSEKLTTNAPEKPEAVDPLASASSTATKVAVDHVFVELLSTIFRDNASKAEAANAQVPKRMEDGQEATTIYYHPSEYDFYQANIDRGVELCDRVRLKVQRRNRQRHEAVRSLAREYLDLKKLWKQKIKRLEKDRKRQDKLRNKQHKQKHKQKSMASTTEAGNPVTGPGSASNSSSITSGSSSGNLGGANDFSLNSASNGTSNGASTVIRTSSRLTNNSSGTDLQTKSELEKMEQARAQMLADQEARKKRLKNALTTVIPDMIITEEDRVSRRFARTTNGQGCMTDGLVMDGQQRLQAEKFVNPWNDLEKCIYMDKFLQYPKNFARIASFLANKTTGDVICFYYRTKKVVDYKALLREQQLRRRGAGSKNTWSCWNLSACAAICLGVKFPEHIAKLLLHQSKFRSHQASENIINSAGAQLLLNSSDKVEVDDGPTSALAWIAMVSNSDSTGSDLQSNGSIGDERDGDSSEKDKSSNSDSPTKKRSLYVQPLKSFVAAQQQPFLVDYTTLLVDNAYSTGYEVSTLSVAERLKTYHMPLENDVDGVDASMDGVAGTGTGKPGISSSMSGKKELKQQRKQKKLAQDTSSSSGLTPGVAGAGGATNQKKKTPASLAVNPSSRNSPRVPSDDKAASSKKGGKSSGNGTPGSRRASGVSSPRIGPTIAMPTSNISISTPDEATAIAALASVSSGAGTPTAVGAPAKRVVQKWTEAEKADFLKFFSMHGKDWATLTDSIPTKTAAQIKNYYQNYKNRLGLQEILKKRIETGGGKGQSGASAGSSSMSVHSPHDGSSLNNDFSQNAPSSGMAALATSQGLTSLSTPELSPSAFGMLHGQSHSGRGEAYGNATNSERYLNFLNQQHQLQMFQMQHQHQPRGHSNEDASSPYSDMKGGQRGLPFGCEQSATQGLTMNSLQHAVAQAQVAQAQAQAQAQAHATAQAHVHAQAQAQAHLAHAQAMLQMHQPRAPYSEVQHSGYYHPLTQGHQQSLTTQLGIPANRSFGHEVGGSEHGASSGVGLSGLMRGDGPPSLLPSSFLGNRDGPARAMLSLAMLNNANSGAPSGLSSALRPPSGSPHAVATSGNLESMMHDGAHNPGRYVDESHSGYNQYDQRDDNRMMKSEAVSNDGGRDSIEQHSLRRDEDIHKREPELKPDVVRSEPGQVIRIPPSSRMSFSSILNDTESPRSEATPRGADPEPVGHQDHDVAAATNVSSRRPDLSSAGQYAAERHSSPLAEQSPTAHLLPRRASNMGLMANLLNVASPAQSPAITQRLNQAEDGERSSNQQQSRHDDSSNSSRGAVNAILNSSVHESQQQISNEGAHSLSPQAAQAAAMLSVSSANPTSAYHSVVTSDAHLAQSMTSASGTMSMQTSTVSSTAQSQSPEMVWRYHQHQQQPLTYEEETEMLRRAAMEKEQLARRAEEEAARAAAAAAAAARALHEARKARQEVMDMMTAKYMAMQQQQQQYPPHPAQTLPPQRHPMHQGVNVPAQHFGQPSHDYQHHQQLQHQLQQQALQHHLQMMQQHSSMGQDHDQRNHSQQEREGGPNNGPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4P2</accession>
    <name>A0A8K1C4P2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008715</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4P2"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438614" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="14359" checksum="8B6E6FB7FD839F96" modified="2022-08-03" version="1">MKLAMWTALAAALMLAALPVEGKLGKTDKIKVKVTARPASCPVRSKVGNSVSINYTGMLASNGVKFDANVDRNAPFTFKIGAGRVIKGLEQGTTGMCVGEKGRLTVPPSLAYGATGMAGFIPPQFTLVYDVELLAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C584</accession>
    <name>A0A8K1C584_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C584"/>
    <dbReference type="OrthoDB" id="204991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="62325" checksum="5B694AFEDD9EF28D" modified="2022-08-03" version="1">MSSALASFARGQQEEVVVDVEEEYAKSEDETTTRPTLMDVAREQAATKATTLMEVAQAEQTKTKSKARTQLAALAAQMDQEEEVASQQRAAKIQQAIELTSVQVQKERQNARAADVRQALQEAVKEAEQAYQDDEFETPEDAMAIQRAAELLTQKANSAAAKPALSADRHVLKQQRRLPPSKSTTKAKTMKEQLSQFQFEQLSTTQRRLFLAMLVDDEAKSTPKKRCNMHVINQLAMDKASKERQQRVLEKTRRPVYAKLDDARHCRFKPRLKGTNQSSSRANDSDDDGDNQRTEDFIRRMEATERVRTETIRRTRAEREYNALVDKKECPQCGNPQSYAELTQKRKKCPNCGVTYRSRLAWCEIADEFLERMAAHLRTRLEWQQRQKEDAEGGAKSNNQKQPAPKTWQHVQDEFLGRVQLDMMQRELSKDLILQELTQECTFQPVISDRAKRLQLGDFDERLRRDLENRRIRQEQYRVLTRAIAKAEAHQRRGDNKPLRGGFQKRLRADLEKRRERLNVHSNQRETSRMAWSTGHKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5P1</accession>
    <name>A0A8K1C5P1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5P1"/>
    <dbReference type="OrthoDB" id="79466at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="26322" checksum="669422CA57EE13BC" modified="2022-08-03" version="1">MARQPPQQQRTVRFKEPMTPPRRAGFWGVTLQLLVFHILNFVLGLVGFVAVVVGFTLGIALVPLCCLGILAFRLAFVFLAFLAQIDVALFNFISPTDEHVYINVPGHNDLFAWDLRLAPNLSSGSFFIAIYFFAVKLVLVLLSFIALAITIGFPIAILVSDPTTQHKFFGSFWSFVLFLAISMFSLLVGSAFMTASASLSRTATRFFCCEKFSVTYEHVADADEPTYQAVEDDDVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5S7</accession>
    <name>A0A8K1C5S7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5S7"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="2">
        <location>
            <begin position="298"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="57729" checksum="7CD1CA10BA21F713" modified="2022-08-03" version="1">MPHRPSARRDAAEAAESNAPVEEASTTSAPRGGGRVSNERALYFARGEAPPTSRRRTSNENRANGPTSPQNGEQSWPGYYATARDLGEQRRAAQEARQEQLERLANGEEEAEEKPVWVPRIKPRSSVLTADRVVPRLQELALMCLARHVELLPTLEYIDADARHRVARAVVKLRRMKPEVLPLFLYPGVTEIDIPDCSYIDESAFLEALQECTSAGLSLTILRLGLCGRSVSDSVILELGDSLRSVEQLKLSGCYRLSDTGVEALVRRCAPSLQEFELSCNQRITKTAIDYFGELQHLHSLSLSECPQLDDSALQALFTMKNLRKLELNQMERISDEFVGELTAKLPDLEDLSLARCSQLSDVAVRAAFENCRNLRHLDVSDLPDLTDDSVEPIRRLGHSLKRVTIGRCLGLTDVAIEHIAIGANNCIERLVMSSLAEITDAAIFTLQKHCLASLETLDISFCRNITEDALGIFTDEAEQLKSLILWGCTQITARFLTSHSRDELITTGHPLLTGLTVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6E1</accession>
    <name>A0A8K1C6E1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6E1"/>
    <dbReference type="OrthoDB" id="166630at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="238"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1211" mass="137787" checksum="0808A274A267EC74" modified="2022-08-03" version="1">MDDDAVSSRWWRLFAAGRDGMRLFVCLRVWQCAMLRKKRRYLGLSPREERAVDFVESGAPLHAMIVFLDDSNEDSGGNDRFSLLQAACTTIPTTTEVLDGHRRLALYYALEGPWVEQEHLSWLVGKSRTQLLQKDVHGTNLLTHAVIHGCPTEILMLMAVEMAHDALESTSKLCENRQFENARRVCVSTIEEYFAGIPHFPHAECRQLLRESDTLAVINELQSVWRAFIDTWGYCGTPLFLQDLPATRHASLDSFLELGVRAKGEPLCYQWYCDDAPIPNATDPTLVIARNVQPHNEGVYHCVVSNWKGQATTTALKLVVIDDRYGPDPPLRYLVNRSGTSLHGTDEVHHVQAQVGALLPHFSGAALLLPPRCFQSLDKNGIDVSDSVGMEVLIRVSPSVSSVQLPHGEVLVSPVLDILPHTVPQLDRRAQLSIPHHWHIHDPLYELAVVCFPLETDPTSRKPTRYQEIESHRVVSVETGAVTVEIDCFQRYIVVARSVSLKNVANEPPLVEMLLMAVYPSSISCRRRGEPVQLTLYLAYNRQDAIHAVNTAITQHQELENATSTTSRVVWLRQNQVVSLRIGRKHTVTHQWRGFSDGALFTRFRDDVRALPYEMAIEGDGDHHDPHTTAFCRIEMILSIRKATTISSTDLYEPQQWQTLIPFLHDAVDVPPPPQLCQRRTNQLALAYTKQQTSIVPAAAPPVPLFEERHEVERDMTPYYYLVEFARFSETFWERYDRMWWFDKTKSNILLGMYKVVHTGVDPFAVIATDAFAGAFRVAQCSLDAAEVYSRPLLLEPPPQEATEDQNELLGDDEDDDARSTVPSGLRRALTLSPSTHSSELYNESFQRLGRVLDQVYPTKTLFTDIYGIACDAEAVRKFLEEHRMRFRAANTEIALVLLGFHLLKKLLRKRVLLKFRLFHHVILERFVLLERLVPELDCFPNEYFAVTIELHTLLRDLFQIVIVHTAAAWLSRLLLLDSQALVLNVLLGRVAHLLQNEAQAMHAAPDLVPVFEDIAYEKTSVSYHMEKMATVRLLREYVLLNVTDPSETTMNQLSACIAHAILAILPPSQRKRLYNDEVCEQIAKELSHKDVRQATQKLQHQETLEQRIQSHFPVHQARCERIPDTIRVRFDRFVSEVDALHVMRVMNASLLCNVNGQVQYNSVEKLLTFTPSIPFERHVRYQIHLRADAVRTTLGTLTSSTFTFEFSIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7S9</accession>
    <name>A0A8K1C7S9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7S9"/>
    <dbReference type="OrthoDB" id="44736at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="54889" checksum="2F074DE1E304F184" modified="2022-08-03" version="1">MAREGEYKTQQSNAEDQYSPPEHKTECNDVFFLLPFLALVITTVYFAISFGPEFIDATQVKNVTEDSGFRLILKYVVTSGFAAMGMAMVWIVFMICAGQVLIWVALGVIIALNIAAAYFLTKQAYDAGADFYYWPAIVFGLMALLLILYTCCIRKRIKFAAAHLRVAGTAIFRLPMTLLVAVAMVFVHVAWSVAWVVGTAGLLFKQDYVKFSDICTEDNCTLEMAVGSVIGVLFGMLIIFFWGSFVLKNIIAVTVAGTVAAWKSAKNTPFITIGAWLRAMTLNLGSICFGSLIVAILESICTILNIFSSMASQSGNCVAACLFSCLACIIGCIESWIEFFNRFAYTYVGCYGYSFVTASRHVFKLFKSKGWSAIVNDDLTGNVFFLGNIIIGACTAYIAVQLVEDTDKQRLAKFEHPDAIVAFFAFIIGYATNNLFMSVVASAVTTVFVLWAEDPHGWQMTRPTEYEVLHSAWLKIYPEEYNNGYGKQQSEVDGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7V3</accession>
    <name>A0A8K1C7V3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7V3"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="8">
        <location>
            <begin position="15"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="548" mass="62665" checksum="7A53A1DDEBA81980" modified="2022-08-03" version="1">MSFDAFVQQSKAENTVVLAGVLFKRPDKNALLWKKRYCVLYKGALQIIYFENKDDFEKSQIRGKIPFSSVHKWDGKPNGFQFYTPSNQCYRVYTETEEEQTAWIAAMQTAIDMAPEKSDGESVAYQRPVASSPTSSPRAGSSFRIVRKDSWREEDVDVPAVVTELEDLRAEVTQLRAELATYEQTEKRYGTEIIREMRGRRGSVLDDGTQVNIEPREMERMRAIFDLFDTQGNGYISEDDLIDLHAKLGEPISQEDAGEAVRHMQHNDGRIDFNSFIKWWNEDHSFSNQTEAMKRYQAKFKFLKARIANPTIGNIETEAVGPFPSFEFRVNFYHTGRNGERVQISPWHDIPLYNADGSVNFICEIPKWTRKKMEIATGEPFNPIKQDTKNGKLREYGWGDMMFNYGALPQTWEDPSHTTEGTGCVGDNDPIDVIEIGTKQWRTGSVVQVKILGVLALIDDNETDWKVLAINVEDHYASKINDVADIEAHMPGCISAIHDWLRDYKLPQVNRFGYDGKCLGRDFAEAVVAETHEFWKLLIEERGGQATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7W1</accession>
    <name>A0A8K1C7W1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanine nucleotide-binding protein-like 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Possible regulatory or functional link with the histocompatibility cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7W1"/>
    <dbReference type="OrthoDB" id="61815at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF3">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="157"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="449" mass="51412" checksum="64D8EF0EDD93BFEB" modified="2022-08-03" version="1">MSSRKKPFSGKAKKQQLKEKRERNRQRRAIDSDDEDASKTEEVEEVVTPVQSGRGDLRTVFQAEPRSAIEKRKKDATRTLVYAADRGNSQSIYEYGIHNQENQPPILLKPKWSLDLTPEELIAAEDEAYRAWIHELETIQVESGQRYNLFERNIEVWRQLWRTVERSDVLVHLADARCPPLHLSRRLLDYIRDSFPSKRVIIVLTKADLVSPQRVMQWEAYVKDQLGDLTTVLSYNQTDAEHCNTSLLKLIGQTGLTIDRSQRDVLRREDEDTLTVGFVGEPNVGKSSLLNSVFERKLVSVSSTPGHTKHLQTHYFERVELLECSSVFNRVLVCDCPGVVFPRLNVPVALQILFGSFPIAQTREPYSAIRFIAENCDPPMDEIYKLTPVEEDDDEWTPYTLCEAYAKQRGFHIKGGRLDLHRAANLILRDTLNGQKVVLSFPPPALTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8T6</accession>
    <name>A0A8K1C8T6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8T6"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF92">
        <property type="entry name" value="LD17053P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="69"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="697"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="750" mass="83777" checksum="0D9E032F3B89A77A" modified="2022-08-03" version="1">MMTPSAFHDDHSESTQSYTSMTRRPRDSGSLQVTSLCSFVTLAPLQAIQRLVSCFGYTHTVHMQSGRTVVVGTEIAQGGFSFVYNARDAATGEAFALKKILCQTEEQIAMAKQEIEMHRSFMHPNIMPISDYAVVSLDTHVHEYYLLFPFIENGTLREMIDISLQQRTPIPERVIFDIFLKICRAVGELHARSPPLAHRDLKPENVLLTRDNDPILTDFGSVAIGDVTISKRSDALLLQEHAAQFSSMAYRAPELYDAGDNTHITSRTDVWSLGCLLYAMAFGYSPFECSFLDNGDVKIVECSYLAVIGTIKFPKKHSRSNSLLELISGASACQMGLFRNLIGGAHLTNMSPTTDPQLVHAHSGEGSTRCDCCKSCGAILELEGCGHRFHPRCVYTYPMTQCEICSTPVTTVKIFRVFQNLPNSMVRKGKWSSDEHKYANMMMKQFQMGAVPLVDGLHLRGFIANLLQCDPLRVTKKYSGHAIGKQNFFYQRQKSYCYNLHTKLQKRISSLRNHFYWHIQYRCKFGYSMNIQELKSAEADYWIREFLKFADKIGQPVEMATVSSSSVAPMSPMPSPTKERVLQQSPPLLAMAAPVLHASVPQHILKEATVNRNVVVKEDTSEQQQQQQLDVEPSFKLESITTTQGAVSPLSFDEWNENPTNAAYTEMLDTTVLDDFAQLSQTQFSAVLSDIISSATSGNPSVNPSNASPSTQSTSTRCSLGDWLVAEESRWNDSKTATSWSFSLTLSDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9A1</accession>
    <name>A0A8K1C9A1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9A1"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF203">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="88"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="29715" checksum="B4616E091162A1E9" modified="2022-08-03" version="1">MRKNGWETPFHYLQFVTWIFFPTIMALFFAFFTPLLEATAAYIGSVAYGVTAVVVIYAVVRCTGTDPSDDSVIRGQRNSHQHTQVGDDQVYCNVCQQYVHKESRHCRLCDKCVEVFDHHCKWLNNCVGKKNYRFFLTSVVGATLLLAIQVAFGAFLMVETYHNTDVIKKRSATAFGCSTELEPSGLCRDDEYHVSITAIRVIHGILLGFLVPWCFLIGQLALFHFQLCVENITTYDYIVRQRKEKLQRERGNVVRVYPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9R6</accession>
    <name>A0A8K1C9R6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9R6"/>
    <dbReference type="OrthoDB" id="73375at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424994" evidence="1">
        <location>
            <begin position="27"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20558" checksum="8C9085F1C6B90E25" modified="2022-08-03" version="1">MTTMLMRWAVLVLCVCFNGGFRVGDALFNAKDSTLGLDMDRIADGPVGWRAWDRFAGFRFEMPHVLDKNELLGAMQRTADVARGLKCFGWIQAVDGDRLVGEARCPKTQATAMLEHLKATCTDDDAFHVKMYTNSKILYHFPTFRVLTEPRYEGKTCFASPPHACEVRETEMYESFARDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9T7</accession>
    <name>A0A8K1C9T7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9T7"/>
    <dbReference type="OrthoDB" id="166707at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11922" checksum="60BF914855A1B4FF" modified="2022-08-03" version="1">MLVIPPSLSDNTILVAYGALAVGLFYVALSKKKHGRRIHNPDSTLPILGNLLDVTKDDRFHDWMLEQCVKFKGEPWQMNIPGDMPTVIMYTPEMMEEATVKQFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA20</accession>
    <name>A0A8K1CA20_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA20"/>
    <dbReference type="OrthoDB" id="166776at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478039" evidence="3">
        <location>
            <begin position="22"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32293" checksum="8C9B4BF05F2844FE" modified="2022-08-03" version="1">MSPRPWRRAALLVALLLYATALCITCATDTEEKIVITTVTGETKEISREEFEAMQAQQASVAKENEWKERQRLEDIEREDPAVAQQIRFASVAFSELQRHGYARGYRLAGFTEKDRVLITTKAELKQGKRKEFQIKMQIRAELDKASGVKANPGTSAHKRDQEPTQISYDVEVLLDQNDGTSLVYAWEVGRDGRRGRRLSIKPSEAMLKRAKEKESQLGETATFARYMLAGGVTLIAIGAALVFIASQAPPSAPEKTKKKQTKPATSPKRLSREEVAKREAGDGWELAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAF5</accession>
    <name>A0A8K1CAF5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAF5"/>
    <dbReference type="OrthoDB" id="112841at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="336" mass="38303" checksum="4A308B7101C694AE" modified="2022-08-03" version="1">MAGEWDLPTVHRKPRGDDAASPTTNDYERRPMLSQDERDNAERRKKRRNAASSFFSGRRLVAFVAVAGFLLGYYAQLLVFFLHVRVGFTGEILPTREVSLAAKFTRELIEDTKRVTFVSKKTNWDFLGFVASPHTVIFAHEDVHIPKPFDETLSIVRHSGVDSYMNLHNKTLTIMSHVHSSGSQFHFFKQDDEAVIYWPHYYQCMNQCKNLGTCYAGDMHVNVGDATNSNSYVFATGGSYFIGNELLKCILDKPVYVRLDGLDFGEDKTVGKMIHYNKCDVQIVSCKWFNNKEIYSPNAVVRMIKGATTRYIVEDTELLSQAQQEEKKKVDAAQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAW0</accession>
    <name>A0A8K1CAW0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DM10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAW0"/>
    <dbReference type="OrthoDB" id="270127at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04412">
        <property type="entry name" value="NDPk7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037993">
        <property type="entry name" value="NDPk7B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109:SF2">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="68"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="432" mass="49428" checksum="BC78165DC938F338" modified="2022-08-03" version="1">MTRSGSAETKRRICSEWVWVIWDGHPECVADPDQVQTRLLGQPPQGESRVKEEQERKKIQKTRMQAIRDTIYSFKARWFDPHAQLNRQYHVRYYVDTHNVEIFDTKTNKLFLKKSDCPPSISGKDFFLGAKVLLYGRHFELMEYLDPFTAEKLGKQQQKAVLVIKQELVAHIGSILDLLLRQQFGLSTLKMMQVSRGQAEKFLEFHRTTGEFGALVDQLSSRPVVAMELVAENCIEKLKQFLPNVGSRFGGKPNEIESSSSVLETQRFYEFFFESAHSMTARLHDCTCCVILPHVIKEGLAGEVIEAIQKGPGVSITAMELFNLDRTTAAEFLEVYEGVVPHFNETVDHFTTGPCIAMELVGTHPENVVAKFRENAGPWDVEMAKELKPHTIRARYGHDRVRNAVHCTDLAEDGILECEYFFDILSKRQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB29</accession>
    <name>A0A8K1CB29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB29"/>
    <dbReference type="OrthoDB" id="5957327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="81"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="36009" checksum="2BAA562CFF796684" modified="2022-08-03" version="1">MELADVELAACGLAPSALALLYKAGFRYKADVHGLSARDLANETGLSAKDAAVVVRVVDTMPKEDAPPPSAYDLLQELRRSRSSISTHLPGLDQVLGGGLSRSEVTEICGTPGTGKTQLSLHLCLAAQFDPAHPDERTSTIFIDTEGSFVIERVASMAESLVTTNAAFRAHGITRDDLLRGISYFRAHDFVELAEIIQSLSDLISSKPDVGLILIDSVAFHFRHGFEDYAQRIRAMDALSAQLQQLTVDTGVAVVLINQMTSKATLGLRSGAMYAPALGDNWAHSVTNRIQLSWESNSRVARVIKSSALAQGAAYFEVMESGVQVTESSEETMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBU3</accession>
    <name>A0A8K1CBU3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBU3"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF56">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="44103" checksum="D658AFEBCEA1F988" modified="2022-08-03" version="1">MESQQENAADRTEVPETTRGLTRELVQQHLSVLGKNPYSQAFVYTTATLSELELTDLNAITEFPHIQHVVCAHNALESLVPIGDLRLLLSVDASHNQLTQVLDFDIPQCMPDHAWAQGGEWIGSLLRRANLSYNQIPRIRDLSTAHPFLQELYLAHNDIGEIRGIASLRFLRVLDLSHNRLRSTHGLLPPGCLEALLGSSTYEIEAMPPRLEALEILRLSHNQITNIDEVVGLPRLVELELAHNKLKQLASLEHCYRLQHLDLAFNALEDVNELNYLIQLSFLQHLTLQGCPIAEQTDSKVFYRARVLRRLQQLVQLDEDEISAKEKVKALAMHGSELASRQQVLTKHLPSERFVNYLPPLEFDDDAALYAFYEQRFGPSEGVDERPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC28</accession>
    <name>A0A8K1CC28_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC28"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="36840" checksum="1F20473290759EBA" modified="2022-08-03" version="1">MRRSGLLRSTKRAFHPRSQVFQPKHRGTTHHHHHQHQHNGTKHQQQTLSEKNIERHHGTTKKPAEPATSYSFYPVQTAAKLVAIFDAVNTNMEMEVAKIQYDYEEYVTRRGTEAVSMDRIVLGSEIDCLKQLKLVAGTITEAMGYTIEAFYDALIRADSGSLAGSGENNELTADEIDQITRHSETLCHLRQQVTGSTVGSGVTPASATRVSFFESVRINILVTVWMLTAGTREEFLKFAAYMAADEALDKCEILRRGGLSVPSDLLEAADEEALENGKAIYAAFEAKVAEELDQRDIDEMEMNIALAAYAGTAEFQAALQQLVSAVLGQANIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCD3</accession>
    <name>A0A8K1CCD3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCD3"/>
    <dbReference type="OrthoDB" id="168104at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="464" mass="51339" checksum="7011D87E1CA5AD73" modified="2022-08-03" version="1">MESTMDSMETPDAMFSLEDPGIQELLSAFDGAGLFPEGFPADLPSFTSIGALGAAHDAFQDKGNESSDGTSTLSEPSDAGKKPPTGNSTRKRMKQELDHLRSQVRDLEQHLETLQLQHKDEKPPVESQESALVDLQGSLWKRVARHQLLERQKSERRNAELRQMLDDQLKVAQLLEKVLKKQPNTVPTLSSFDNEAEDPATLTGITLPSEDPLVFPHLLHKVQVAYDELEDMCQRTGFASSRRECNNTQVHADSSNRLFLEVLNAKIVPFPVEATSAVAWQCLSQKILKFINGLYKGTKTADDTICAKSKVFTRVGLAEATMDMAIVTKRFDEPNRTVLVLQAAAVGIGSRDIIDNLKFVEKGWVIMRRIQVAREGNAETDDTPDMTDSTLIQVCMHLTPVATARAGESTPSATNSTLTDLMLAAFHENLGLLYQTIENLLMEEAISTRHRPDFQLKPGDDPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCY3</accession>
    <name>A0A8K1CCY3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCY3"/>
    <dbReference type="OrthoDB" id="19861at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="17526" checksum="E46F990D000A5020" modified="2022-08-03" version="1">MMGVEEPKELSSAVLNFPKDIPFQYDYEVDTFYVRPCYARYYEYITNKFAETGYTRKRGVTVTGTPGIGKSMFMAYFFLRYRFEHQHENPTIIMTSYNTSSILEEIVLWKDGLKSEEFYYDLPHLKKLYHEYPNALVLLDGPPAVAPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD49</accession>
    <name>A0A8K1CD49_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000982</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD49"/>
    <dbReference type="OrthoDB" id="164055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF18">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY MEMBER 11-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="10"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="335"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="576" mass="62257" checksum="8A6C73E36A7F7F48" modified="2022-08-03" version="1">MSLPEWKFLVFGSVGGIMSAMVFPGLGLFLTKITFLSFEDKPRNNFLSDARLWSVGFLVLGILAIAGMTLQNYAFGVVAQRLTSRVRLVAFKAMLHQEVSWFDQDENASGALVTRLATDSATLQTMTSDTLNQTLVNLSSMGIAFGIAFYYCWQMTLLLLATLPIFIFTGYIQGQMTSGTISNKKVNDADSAAGALLSEAISSIRTVASLHMEGSLNAAYTAFLDASKSADKKTGLIGGLAFGLAQDSLVLVFALLFYVGGKWIQSGTTTLENMLTVVLAVFFSMFAVGLAAQNMADQTKAKKAAARVFNVIDRTPKIDSTSTAGQQLTSIHGNIEFKNVAFTYPSRPDAQIYTNYNLKIKSGQTVALVGASGSGKSTAISFLERFYDPAAGTVTLDGADLRKLRLPWLREHISLVSQEPVLFAGTIAENIAMGKPGATREDVIEAAKKANAYDFISNFPNGFDTDVGDRGAQVSGGQKQRIAIARAILRDPEVLLLDEATSALDNESERVVQESLDRLLALKKRTTIIVAHRLSTIRNADLIAVTKDGAIVEQGTHDELMRIEDGVYKGLVARQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDF3</accession>
    <name>A0A8K1CDF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1736 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDF3"/>
    <dbReference type="OrthoDB" id="66906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052346">
        <property type="entry name" value="O-mannosyl-transferase_TMTC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="5">
        <location>
            <begin position="264"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="750" mass="84738" checksum="61101FF9BF8F4F89" modified="2022-08-03" version="1">MPMEDEVVTQAAAVGLTALLTAWNTRHNQFVWDDRAAVLGNAGVRRHDTSIWRLFKDDFWGTSIDSVNSHKSYRPLTVLTFRWNHYWHGIDPYGYHLVNVVVHAICSVLVWRTAEVIMRLYAPKKRVRVGSIIAGLLFALHPIHCDAVASVVGRADLLCTMFALIGFHYYVDGTTSQVHSTHQKVYYVLAGLGLGVAASLCKELGFTTFALYCAYDIMRGIKEDGVDRFRWRRRASRVGSVVLFTLVCAMLRVSINGEHRQMVWNKLANNIVVQESKLTRVLSYAHVHAWYLWKLVWPGWLSFDYGFNTIPVIESILDPRNLLTLLAYAVVATGVAHGIHTVKTSPVLLMISFGAITFIPASNLFFPVGTVVAERLLYFPSAGFCFLVGYLMEQVFDIHDRVTLPGPLDSVLTQRLWQGLPRILYSLMGLILLAASYKSYVHNAEWRTEKSLFDAALTVVPENLKVLNNNAKVYLNSDPLRAIRYGLLSTGMMPNQTEAYLNLGLAYGINHQDFLAIRHLMKSVAFSKWSASSAGYTGAYLYRYWSFQHDEQVTLQQALGSPTVRIAKQLLDKAVLLKSEHPDHYFARSHLGYIRCDRLDARNHMQTALRVNEKIQREGIDMERMLPMGDIVNALAAYERLLGNTDTALALLLDAMKTDSSNPRLFMNAGVIYFDRKQQGPAKELLERALELGNNPSFFRDAGRILEGLQQYHAAVVFLRKGEKLNPEQTELFKSDIKRLEAIINANTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDJ1</accession>
    <name>A0A8K1CDJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162437at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="456"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="798"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="855"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="880"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="995"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1344"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="1144"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1376" mass="153838" checksum="F665D24AE202BCCE" modified="2022-08-03" version="1">MAPASCSVAAGHAPARERTTQHARQDAEKPRVAVDTHPSDVKSSAVAARVAREATRLGDLLLRMTQISPKHQKTQEPACSQRLRVSGGHSMLVVTVSCVLAMRAALMLDLPLRLQQFIGGILLVASAGTMYLLLCYLLSTNERTFLIGDLLLDRSNPLTWNHDRLRYFLEVCSWMASVWCSYAVFHSLLFSILGGALAAVGLAVFSDFCAAYIRVVKERMNKHRRQALKQVAWVKGGLSYLCVGYVITGNWRNLYGFLSGERGELQSIEDLVFGYLLITLVGVSLIVASELLLLYEPTRNAGITLQSRIVDARRNWEERTWRSMLESTAVFGTTMVSYHVTQDILTSLQLGTLVGVALILVGDALSSRFIMFSRRPDAIPSDHWIKLVPVGVMMFWFAIQVGSVLVNLVTLPSSVGFTLVWIVTISAISLTIIALSDNQSVIGRLASIGRELGGRLCMLSVTGIAFLVCHGWPAIAFSTLLSWFCISLSRECWNEIEAREARRAQQGRTGSDATEHHKIPVVMEGDDIESPSWSSFVIGHVRRKYSYLYKRVKWTFIPIVVLSVLDVCSTIFVMSKNNTLELKLSQFSAGNVVVSTGVGYLTSNIRRELHPEVLVKTGVQHYKNKWILFPLHAFIEAMVFLAVFCGTFAATSTVFSSITLASLSGIVISVGGHWVCSRLNLSVGNRTRIQLTASCAIVFCLFLVAWVSLVCLFSIYHYIDNLEAAFCLASLAGVLFLATSELFLLWEPTREIGHILQCRVTHAKENWMAEPLRSFLEVFTWLAVICGTFALYDDLLLALQLGTFSGIALALSGEFYRRNRSKLIPWEDGMNLAPSSDTDGFMSKELDQNAERPRVLPAMLLFAYIGSGTFQWIYENIRSLEVTVVLATFAGFVFLCVADLLVQYRPTRWAGIILQDRFLRARENWHENPVRSFVELGCFLGVIYGSYAIYGDLVVAVQLGTVSGMLVALFGERLRSRARSLPLAGEDDLNDKNQILPLPVMSLLGLVGAVAFNIIYTHLRSLEVAFVLATTSGVAFAVLGDVFVRWKPTRKVGLILQERILYIQYNLKVHPQRTWIELLSLTAALYASYGFLWPKDLLVAMQFGTFTGIFTCVCDELTMEYIADFEQNVVQGASRRRASHAQPNSDLLALPYEIQFEIAHFLSPEDLLVARATCHKINNMLRAESARYWLYSSLRRKFRNLQQVQTETRVADQVRSLVYDAITLVLPRIFIARDRTEILASGSGLSRTLKWVYLNAEWIRSQGLVPLAERHHIPTITFQPGDAGFDVFRHMPDKAFLNITVERDESMLIKQISVPVGVYAKIQADPLSFVAAETLSELDAFSNWHIAFVVFSAMTLIFIGQFSSVAIREHMLPKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDX1</accession>
    <name>A0A8K1CDX1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDX1"/>
    <dbReference type="OrthoDB" id="58154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="39202" checksum="4C37D552C6C8684A" modified="2022-08-03" version="1">MMLRSGSIAVEDDGDDASLLHRTVVPIDAVSAEMPAAAAPLRTEAEELKARFTWSLLLPALAECLTTCFLPDWYVPGWRVNATATMINLVGPFIDGMAYGYEEQLKEDAPVAPCLEFRAAFLGAFTSYSFMVDHAGDLSKDSVFEGGLYICGTTVAACYAFHLGKVLACSPKWIRFLDLWSRSTLIAKMPSFMLGSNMLICLTLVRALFGNPGFVRDPKDPQFIGTIKVADGEELVLGIFMSCTGILVSQYLSTLLKPRPDANGNVTVLDWSNLICNFLSCWLTGLAYEASKLSPGAIRNNLLIKKFVSSFCGSLSSFSGGISEIMLLWHADYRRGASWNLFLHVVAGLLFLPYLHKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF77</accession>
    <name>A0A8K1CF77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF77"/>
    <dbReference type="OrthoDB" id="163947at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475816" description="Elicitin-like protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="24743" checksum="4399962936473D4E" modified="2022-08-03" version="1">MRPSTTVVAVYGLALMASTGVSGVHAATCSQDMLSAQNTFVQGQKTLFQSCLNDLKISTQPSSNDAWMSFVSDDYLSGSKADAICATDNCVRALIAVMETLPDCCSQSSSGVRNLPRLADDILHQCDIRDARKLAEELEEEIKKLPDLKVQIQSLQRLDAHSSSSSSTAGTSVGDGVDVIIDVKKREMMKTGGYGLVQSEKQSGNAGGADSAAISSVASVSSLVLALGMAIQFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFF9</accession>
    <name>A0A8K1CFF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010883</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFF9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF81">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE CEPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429695" description="Protein kinase domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="659"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="686"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="948" mass="105020" checksum="A9549821601CBFB4" modified="2022-08-03" version="1">MAAKISLTIVLWLVLATVSTNAESNDTLLCPANTKDDDQRPVIIADCVSICGYEGFCIYYPYQYRQGCTGGLANRCVEAKECTYECFEESPTEINFYQTWDDVVEYAIHTKAATSTGYVNSSLVQGFRADALASKIVAFYARLIVLDLFDVGNAQYIPPSPPVPFDIPESVVQGDPARESLRIVSVPCPPFPSEPQDFSMLHSLMLINCGLTELSLANHKLPTLAMVWLKKNQLSELPSLPPSVTHLDISENAFTSFPKTIRNLKSLFGLEFKHNLVKDIPANSLPTNLSYLLLTNSSLSKVPADIAKMDNLTIFDISGNVVKPEDLALLPETIVNLRIQDVKLSRIPSAIGSHFPSLTLLDLSSNPLESIASGELLSTLKTLIVSNAAFTKLVDDALPDGLTEVNITNSKLEAVPQQLSVYNNRDMINLSRNKLTTVDEMSAKTIVLSQNEISLFSGFIQDTIVLDLSFNRLTTLNLSSQMDSIKILKLRGNNLTTIPMSVFRQRALQVLDLRDNPIEDYLPSSQEWPFLQRVSVVRMDANQLRTSCSKKVRFKEHMICDPSLGDANSRGESSDSASGDSATATESKSGASSHTLVITVSVVGVVVVLLAIVAALYYRRRLIAVSKSHSTNETTASGDDRLVWQDEDLARHRLDASLVKVDRLLGTGTYGEVFLATYQHHRVVLKRLRNSDSSRQEIQRFVNEIKMMTHFRFPKIVRFIGVVWTKESDVAVVTEYMAGGDLRAYLDKTKRRARDGWAVEKYRIALDIAEALVYLHSLDPPMIHRDLKSRNVLLDREMNAVLSDFGTSRPVDTERTMTAEVGTALWMAPEVLTGRRYDQSADIYSLGVILSELDTHELPFRNTDFQSMNDAYVVGGVLAGSLHVRFLTSCPESIRVLGTRCTALDPGDRPTTLEVAYELRNLLRGQVQASSLSSSRSGSTGARSSIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT1</accession>
    <name>A0A8K1CFT1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT1"/>
    <dbReference type="OrthoDB" id="124228at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="52884" checksum="B0AA43D12182D115" modified="2022-08-03" version="1">MPWRFLRMEEHFELIKANFIRCDECNENFFFDFLRHPRYFVAHFKACHLKNLLYRFNGHSEEENQKIRFGPRRKRDANAWFGQLKSTEKRMISMQDNKWSEITESECWSCRLCNDGKADLTHVFELNELGRGQAFLHLRQFHESAYEAFLRSLPDVQSSAVVNLRSSDLPGGSSSHSSSTHSTASTSQVAPNRSTQQRMAEAERSRQRRLNATDEERRLEAMRSKRRRENLTPVQRQADYERRRRKKKRLEESERSRKRREEASDETKQKELLRSRERRRNATEEQRQREALRSRMRRQNATEEQKLKERERCRKRYEAKKTAKHQHGEGGAEDGEDMEDHDPGHGAARLEYYGTNQVTDDGESEYFTDRSVESTTRRGNAMHDAVNQSPSTSQAFRLPPPQSNTSSAFFTAQLLAPPPSFLAMMQRPGPVSESSVSSGRPSEESDGQQQQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGA7</accession>
    <name>A0A8K1CGA7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGA7"/>
    <dbReference type="OrthoDB" id="64020at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="880" mass="95801" checksum="2EDA27921DFB10BC" modified="2022-08-03" version="1">MMNGTGASGSEGLPDAYAALTPSSSSPASASFSPNVSMAPVASSQMPASTVGSLPLSHDEMHPAKRPRLDAPAPPTAMGGGNANASMAAMNAATIAAKRAIAALPTPTGTNGSGMTTQQFLQSLPAAYAMSNPSIMMMMQQQQQQQQMNRPMANAAPVSAMQQHQANAMVMAAMAANAAAQNRLNYPNVSMPTQQMGVPTPTFTPAKPVTPQTTAASLATPSTPPADHPCYLCKTKGDVWVCNAGCGLYAHVRCIGEDKVFPSNAGQICASCFLMPQDRNAKENLQKGGTVGISVRRAILCLNVETSSPQNFDKFGHLSSLRMYEIAEIAGYPIGPFASKFVEPVLQRWIREKLVNIPKWPLNVRDVFTLMIGLYSLKRANIAHAWRERAVDLVQAKKFSVIDYFGWHPAIEGPQVRSSNLCTICCIRNPPELQMCGRCRRMLTFPSTFTKFASTLLATYYAEQIGLSLGTTVVDVFAHTNTVRGLYKGLKPLDGDGYDWESFAEQMRSIFGLLDVVSHFGVLQLNPEHFEPEIKIIFNPLYLNQAMLAMEYEVVGRFLQCLKLFGPEKAADARSMIENCERFLLMRQLPNGSWCKMTGSVVDQYKATVQCAKALVTPVFRGFGPTIPDLRRYLEKWAKKMPLHAQRLQTVGDGKLLVNGVTVHSVTLPQLKKIDVFYRRQIIPTSGLNSLETLATARLRAILASQKDDVKIKEEVSATTDNEDTTENESINIKTGMLDDQDITMDAQENDEDTLTKLSLNGELSLFDGLKFEDGDVIDMSHHGVGSINGEDDDDQNESTPGPDSSAVEDEGEDIGDDMYDDDDDDNDDGGEDDARLPEPEPVDIQETGDVGAVEGEETSELPPFDESFSQASIDLALDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGE5</accession>
    <name>A0A8K1CGE5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGE5"/>
    <dbReference type="OrthoDB" id="168471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="23040" checksum="40BC48D763051B72" modified="2022-08-03" version="1">MGCCPSKQKAANNGVEDGYRVQSSGKELQLDDSPVIISVSVVDDDDLSPGSAPTNMLMDRGDGRPIEYSDHDPSETEKEEPGGIDNQNEEDVTVTVRPAEICVTKEEQSRVTEEPKPITVYEEPKPITVHAETPWSNNDQHTGVTPVSSPSKQRISVEDIPINSMYHRIHLVEVEEQESKRQQEIRAEAERREQEIREYKASLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGL5</accession>
    <name>A0A8K1CGL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126967at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1579"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1861"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="502"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="671"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="552"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1609"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1637"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1664"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1721"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1752"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1783"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1806"/>
            <end position="1821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1832"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1874"/>
            <end position="1895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1895" mass="208803" checksum="EA6934BB07B1A9EF" modified="2022-08-03" version="1">MDADNEKKDLAGRVKNMRDMFEKAKASPSTPLTKKVLTEEQQAKAAHAQYRAPVYSLENEALRRQKEQREAERKAQQDAFNGYRRSQTTKTIYDVASDNQKKREEDERRRAQESKEMYVKAARTVVEHDGLRVVRERQEAVRKAEEDAITATRRFKSGVTLADIAAERQKLREEEERRIAQESKDLWAKSAKQAVEHDSVRKLREQREAVRKAEEETMLGYSRIKTSKTMADVAVELTKQREADDRRIAQEHRDLYAKSSKVAVEHDSVRVLKERQEAVRKAEEEAITAARQIKHTVTIYDLAAEKQKQREEEDRRIAQAHKDLYAKSAKTVVEPDWVRAQREKNEAVRKAEEETRESFRNIKASKSILDVASDMQKQREAEDRRIAQAHRDLYAKSSTKHVEHESVQQQRERQEAVRRAEEQALEAQRRASASKTILDLASDKQKMRGEEDRKIAQAHRDLYSKSSYTSGPEYEFAQKNREHELRVERAAKESLRKFSSGKNFLDEKLEEKKRVDEELKQKELEARTAHTQIKAKVDLARDVFMINGVVQPKSAPSSNNGSAAPSPALKPYPFSDPGARHRVSSNPSAMEAVAKLQAQIGSGELDANSGMTYFDLHVSKLRDQEQQDRDSEQATRDSWSRNSLGGSASLGPEDLKAIEKDLPTAEEIETATKLVKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKFAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAMLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKFAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQESELRQACKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEEAELAAKLAKEQEETELAAKLAKEQEEAELAAKLAKEQEEAELAAMLAKEQEEAEKEERRAKLLNSRAIKIQSSWRGKQARLAVEKVRSERIERKEAVSSFTERRVLLSHESIGAGSFGDAIDAAEAVTHPTMASVVEVSDSESDVVKEELPTGAIESADVAPVSKSSDVSNDASMSFVSSTDVSTPPSSFDTQDVQVDSQNQYDQEGLEQGTPRASVDSNDRDSYGDLRESVFSDRLSESISERDSSFVGEQPSLEDAEPTTPTDNQPSLEDGEPTTPTGNQDEPTTPTDNQTEALVEEEQAEDASKATTSRWAPTSLFGKTSSPEDSPTKSAVSTVSGMASAAGALFARSASTASRHLSRSQSVDTAPTPLSRSGSGEEIEYDGVSPTNAESAPKSTGGRFSLLKNITSNATAAAPKSLTTRFGWKRSSSTAAAPAATPKDAPDSSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGU7</accession>
    <name>A0A8K1CGU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGU7"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="94" mass="10921" checksum="45453C6133F371D7" modified="2022-08-03" version="1">MWGAKVKMPCDMEDDVLEDAIKLVTARIAKYDTEEWEKNGLGVCEEIKAHLDAQWDPHWVVCIGRNFGSFVTHVTRNFVFFYYNEKAVMLYKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH29</accession>
    <name>A0A8K1CH29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH29"/>
    <dbReference type="OrthoDB" id="339151at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000003">
        <property type="entry name" value="Nuclear transport factor 2 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="5">
        <location>
            <begin position="18"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="350"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="509" mass="53821" checksum="A5A82C3C3CDEEB04" modified="2022-08-03" version="1">MPETAASPAAEVHHPATVGSTFMRQYYHFLAKEPESLHRFYKEESQWCHGVGSHMQEPIAGQKAINDEILRRGYAGARVDLDSGSIDCQGSLNGGVFVLVTGVMTLASSHVPKPFVQTFFLAVQPKGYFVLNDCLRFLELPGASSAPSATDAAVAPKDVKKTTHAAIGTPVSASPKPKAVTPVAVAKKDKAAVSPATKPVEAPKSPVKAAKSPEKKPATPKAAPAPASPVKAEKKVSTPKPSETKPASPAPAPAKPVEAAAPAPAQAKPATPAQPVVQKHAEPAAPKTWAALFNSTQAVAALASTAAAPAKATQPAAPKATPAPASPKAKPAETPSSNATAQSKEKPRYFSLYIRDVPPQTKESELRDLFKSYGAIANVTVPQGRGYAFVDYVDQESMRAALADEKEFKVHDKVLQVDERTERKDKERGSFRADTRGRGRGGPKGRTGERKEREADGKDRRAAGEREGNNNANGRSNTNGPRSNNDRREKGGRRGGKDEGAGRGANRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH31</accession>
    <name>A0A8K1CH31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH31"/>
    <dbReference type="OrthoDB" id="59491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="328"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="754" mass="83843" checksum="83A922404914972B" modified="2022-08-03" version="1">MTFSRTTIKTPEQADAPRSLHELNALAAVGDVLDKPQWWTQWTNEPAMRAQWLVEMEELLLRRSVEQTLAAWPARPAIREYLTQYLEPLALAGAKKDKAIKNLTAHVLFPVPSGLADSTFSEGRCQDPLDLLDDQEYEDSDEDSEEEEEEDEACEGEDDSEDELALDEDGNVVAFDAAVEQARQKLPTGDEDMEDADTDNEEGEDHADDLREHAKKNPFGQIGWYCNMQILQEAVKPLASSQWTQDVLQGPLNVAANPSIPLVVGRTTSFISGVLHGSGDGSSPTLEAIKAHIPHEEREDVLKILLLHCTKIHELVEMTKLDAAAVLDLIVEELALGEDTLSKVTPGMTPQTWLSDSLIPTGLKSKLISEVAVLESQPADRHDWQPHKDKQVLNLINPSLYPCVFGQTTRLPLHQANKSYPSAADQMRSILFLPAKTKTSGPKGLKFQWIPSEVDVDLEEDGGHAAFVTYINNLHPESFASMYTPLGKIFGRLVPLFDRVLWTLEDEARGKLMGDTSRDAVMFFQSKGYTHPCPPALVPLGLFNPGEEAFSLRGGRCQVIVKLTEFHLTPTKPRYAGGAWRVEGTDAEKIIATGVYFFGSDNIKHAGVSFRTLVRPSDSGDEVANGLQYGLGKEETHTQDLGTISALEDRCLVYPNTFQHRMEPFELADNTKAGVLKVLTFFLVDHLDSIPSTAVIPPQQEEWMERAQEPNSKRQRLVDIANLDVKDNDQSRVGMSYEQAQQVRLELLNDAADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHD5</accession>
    <name>A0A8K1CHD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHD5"/>
    <dbReference type="OrthoDB" id="70570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000345">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="217"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="601"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="635"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="669"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="418"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="469"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="711" mass="80030" checksum="50F92F37FD6B4972" modified="2022-08-03" version="1">MTSRGRSDTTTTMALPRNAGLQFAERREYRELLHAVQARPELAQQRDEFVMTPLHWICTDPDVPQRVLLQVILAFPSATTLRNLAGLLPLHLAVRKELPLDALKVLLKFYPKAIVLDTPGGRSTLDFALEYVTSHSSKVFLRMMEQQVREMGHDPQPQSSESNRNKSLPQRTASQRSHGGDSQPHESSVTSQTSSRELAPQDADEDQTSVTAMLPQWKLRKYCNVCDIKFGYFKNRHHCRNCGESVCGRHSNHAVSLKHLGLFRPQRVCSQCYERLQSHYTTRAMARMSPRSLTTLLNDATYEDNLPVEYAYSPIARRDLRSRSAFELPTSAALEPLMSPRDFSKASPKTLDKLDLKTRSARSATMSPRSSRTATSTSSNNSSTSLSGPTASKTGVQSNFQLMPSLFSMHMTRIQRTDDQLTVQERQAEMQRRRDRLVKTDLDAYTSSRQPAQRSSDVSNQSVNEEDHAMQLEIHMERLRLAKKQIQAALMRSKREAQIAREQRERYAIIAQAYEDRGYTCENEDAEPQGVSNDSVDDSSTQENANVREGFNYNILAHEDRDSEIPLPNTLYATVPETTPRDEVDESPFESDSLDIPLDVAQTHHELGVLFLSKEEYGRAVIELEKSAKLDASNALTLYHLAKALDGKGDVAEAENAIQKSLALEPNSVPSLSLLGKLLNGRGNHDEAIEVFRRALSLQCPQRRHEGPEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIF6</accession>
    <name>A0A8K1CIF6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline/carnitine acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIF6"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004095">
        <property type="term" value="F:carnitine O-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF16">
        <property type="entry name" value="CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="6">
        <location>
            <begin position="51"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="628" mass="70581" checksum="2817AB8703F97890" modified="2022-08-03" version="1">MRVLAPLPQLQRASRALRGLATASSSVPEPLPLPAWFKRMTTANEYALPRLPVPQLGDTVQRYLESVRPLVSEAEWKEHAALAARFEAEEGRKLQEYLLKRELAQALSKSYPYSYIEADWDQMYLGGRYENPINVNPAYGLLDETDGNLKGMVPRTAAFVRSMVKWWDKVKTSELEQDPKQCMSSFARQFGTARVPQKDRDVLESYPRSNHIVVLKGKQFYQLDVLSPDGKQLLSQSSLEQRLNEILNYSDKPEHDDVDLSMLSAENRDTWAQIRDELIAHHPVNEHSLRSIDSALFVLVLDERSSNDTVKRAELALHGDASNRWFDKVQVIAQADGHLAVNFEHSFSDGTSWNRWLHEVWHDMRGTDSGFAPLKELPEYTDATKPTLLSWKLSKNLVEDIKKAESHFQKFAGNLKADYLEYTNFAKKNCKTWKLSPDGVAQMALQLAFLREHGKTPATYESCATRAFHHGRTETIRSATPAAAEFVQAVQAGENKALQRELLVKAVNRHVEMAKTAQKGLGCDRHLTALASIANEIGLKSDFLQSPVRAASTNFQISSSNVTMPFLNYFNFGAVVPHGYGVGYLLHNDTINVSLTNYKDSGVTDSTKFKKAISEALDTVKELADAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ81</accession>
    <name>A0A8K1CJ81_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ81"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF50">
        <property type="entry name" value="ASSEMBLY CHAPERONE OF RPL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="338" mass="38273" checksum="909AA57AD6BE8DA6" modified="2022-08-03" version="1">MVKKPGNKADYSVAELVAKAETLVDQCQPELAIRFYEKALAKEPSNTTLLDIVGELSLELDNPERAHAAFQQSIQLAPAQNPSKWFYLSQLVPGEDAEKYTTQGITYLQAELQHLDAQSAEAQVIKKQISDAFCSLGELYMTDLCDEDDAETKCENFFQEAMKFDIGLPEPTQALANLRLVQQRKEEAAELMEETYRRLNENCDENSLPSLEFRIATGKALIEVEMYEEACDVLEGVMQEDDENAELWFLVGTCYRAMDDLAMSLEFFQKCEEMLQKLKKELRGEFHLDEQLDSVVETIAALKEAIANRGDEDDEDDEDDNDDEEQAAPGTEDVDMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJI9</accession>
    <name>A0A8K1CJI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJI9"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051942">
        <property type="entry name" value="DENN_domain_containing_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15288">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15288:SF0">
        <property type="entry name" value="UDENN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="170"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="886"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1187" mass="131315" checksum="BFF865404C6A65A0" modified="2022-08-03" version="1">MSDSDDDAGVTHPRQKSIFSTMGRVRNMNQFREKWSGRASKLPSASSDYASDTTLTASSVSTVSAASSTKKRAHGADAVVTRPPVEPPRQPMNTLEAQRYNALHAWIQQSGIPLQRSEGRSGSGNVFDDMYTSLDDLEAAVQQELASLPTDPRATRASEPVIKRQDAIVSYAVVIGPELTDLAIRQSDVLEASVAFAYPPESQFTAESIDQFCFPRGIVVGYASSSRLDTEHHEFFVLVLSGGGDQGQNVQYGCCLRTVVKVRCLNGQAVDLVVPVCYCVVAVAPYIPFLRAILIHIADVHQQELDAFKQQDVVSNIVPDSLSNLIDSIMTSIAQMSPPKIGGEAILTVESAEFRLRRPRIDAGATESGTSLLMWALPVLLDHISITKLIQALGLLLVEMKVIVVSKSIPLLSATTLSLSALLHPLVWAGPLIIILPPSIHEYLEAPVPIICGVDALPRYFEHTKGTAVINIDTNTVILHSEDQAQHGALQVPGGEELTLELTEIAERISLWRKSSLSIAHTALVNAVSRRIRSHLERLLQVCSRINPCNVYACMKQEQLSLSETLFLKSFMQSQIYQKYTDDLPLAGKTLSTTEKPRSDPLLSPPKPPVLISTGLKDAIHQLFLIALTGDSQIRPREQSSSATSPSSVVPISNQDIEGSSRDDPLPLEDSRSNELTDGETKEPIQPKVDLTSQKQLIPLPVEIITPSSPIAGSVVAVRPKTPWLSPFTFITEVSSSNNAEVVETERQSYTIEEIAKAPFLDLPIPSPTKRHSASYASSEYDDLMDSSRYDLSESRRADTETTISLWPTTEVDDQGGDDLRRTQASGAQSPLSPVNNEFYARYSNEETSPVRANHRLMLRYAIQDAACVKIQTAWRRWRIDQANARNPLSNRPAQPTESEKAKTKLSKRSTTLLLIQESGQKEVLMHVSEDGMTLYWEMAGRSMGSISVLDITCINASDGTVVIQTMRQEHAFLIQPNRSIDVMTFFRELHQDVLGMTKTPSTRDDTVSEPKSTRKDSSCRESVNQHRQDSLRRANDVQTPELKHESNELTFPQQLERGILVLKHGRLGRPHPKYLICDEARRILFWCEPNVTNAGYLMPDRDSAKHSRQNTSEKSIQLNQVSEMRHGKQTRVLHRSTAGRSDAGRCFSIVTPKRTLDIEAFSQDQCSSLFEGIQQLVMDAREEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJX7</accession>
    <name>A0A8K1CJX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CSC1/OSCA1-like 7TM region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009004</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJX7"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428212" description="CSC1/OSCA1-like 7TM region domain-containing protein" evidence="9">
        <location>
            <begin position="27"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="635"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="674"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="721"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="820"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="149"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="10">
        <location>
            <begin position="635"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="948"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1053"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1061"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1095" mass="123783" checksum="83E5614B66093B1A" modified="2022-08-03" version="1">MRRQMRWKPCLLLALALICAIRPAEASGEVVHVPMGITTVVLGSQLTQQIECDVQPLSRVQVEMKVLDGNGSAVEDTAKLVKPSVVTFSNTDPLMTLTHQTRSVTLSGLREGRFYLTYHLTGDVDIYRLSALSSVLLITETGQGWQGILYELVFNAIIFVAGVSFFAWRRLHRVDLPIWRRQQAGLFERANYGLLPKKAFEKRYREVLGSDLRTRVRQFWKIRCDGSYVCNTCGIPAALLMRFHIDAAHLCAILSVFSVGVMLPVNYLSGNTRSQFQGNSFQQTTISNVPLHSDWYWAHVAYCYVVAGLVLAFLQRQYQLLAFLRRRTKRIVGGRSILIHAGLPTTTTKKKLRALLAEYYPDGVDEITVIYDLTKLHTLLDRRCELSALLDRKCALDAANENGTLSCSLIWLPGSMMVPSPWEMMMAYLTCRPCRFYARHWRRTCRSCFSCCCCCCCFRRAYKPRADSIAKEALFASSTSAEYVIVRSEREIVDPRLADEIDALDEQLEFFPEEAIELYDKRQCAGAAFIIFDSTAMRDDFIHLVREHSWSGRFVNRVADAAHHARYGSTRPMLRRQPAEGEPSEQDRHHSNTLHRYLSKLVLSSAPEPDDIIWQSVKYQPLTISHVFMSLLRQLATISLLLLFSTPTAVLVFVKLDAGSGIYPQLYARHSVLVSLVATYLPSLLLIAVNWALLAFLFFMTMSEASISDTRRVRSFLIKGFIYLVVSSVFLPSIGVTAAYLAFAQIKDNGKSYVESFLYKVSGTFFISYICQRTFLGSIIELTRTAERLAFQPWVLGRAVTLDEQREAVKPWPYFFGHDYAMLLSIFLVILLGTVITPVLTLFGALYFYIKFVTVKYNFLYVLPYTPGSGHIAQTSYTLVFVCLVLFELVLAFVLLQIATRKHFVAMIVLLSATCAFYFLRLADETTRIHHRMSTLRSDTLARALSRATEATTSTSTQKTKAPTATTALLHQSSTPSTPSTVAATPMHGRRTIFSPSPANLEQELDMIESYTDPYKVALSIFKFIGVNEFHRMKSSRAQLLCAFHRLKRNMHAAQRRSRRLSGSMTGSRAHSPTASMRQDDDSRRTSTITTADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKB9</accession>
    <name>A0A8K1CKB9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKB9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="142" mass="15332" checksum="CB64D40F44E7EF14" modified="2022-08-03" version="1">MDADQWLELEASLCANATSKLSVALKEAFPAVTSNYLGTCYPVAMLKAVQWCAAGNASASESPFGELQKRALQDGLDRWQFSVLVLHSTLAVLLLMCAFVLVPLLQFGWLYLRNVPGDGAFVLISPRGNEGGRVSEMPVLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKK1</accession>
    <name>A0A8K1CKK1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKK1"/>
    <dbReference type="OrthoDB" id="164509at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="204" mass="23717" checksum="7A62DEBB35327538" modified="2022-08-03" version="1">MADTYAAPHAPTNLFEFAEAVAPIVKYYAILLLLYFVAKRMNKALEADKNELRDRPVLSKELIETSDEEDDDDDESEEEIYEELVTDGSRLVKMPNGSTETQQVRARKPKKEDKVKVKSESKTSRDKTHPLFEGLKKIEEELREQKDEDNNVSWNELHASMLRRYQDKFPDHGPRTATGDDYDDEFKELLKKHNVDIEQLKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL06</accession>
    <name>A0A8K1CL06_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL06"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="16"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="215"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="30676" checksum="F2E2BFCFA85AAC1D" modified="2022-08-03" version="1">MSELQSLRLQRVYENAKRSLNIETQVCFSGVHTQVTMYHMDISFRSTRNKWTIAKRYSEFYKIRRTLLKFLKQYKHEFGDDCPLPLKALEAALEAAFPRRHLRGDTPAIIEERKPALEAFVQLLVKVISSIPLSDASPLQALSPTATSELAATELTREGESMMVLYQILRDFLEYPDKQIESDAKLKLAVLSLEDVVVSSRSNILETDACLSECCSICLGEWHDEECVDMNVVKLPCLHAFHEECLMEWLQGNTHCPMCRDEPGVASGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL88</accession>
    <name>A0A8K1CL88_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL88"/>
    <dbReference type="OrthoDB" id="126479at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF35">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="653" mass="73125" checksum="B2E664093C5ECE08" modified="2022-08-03" version="1">MMASAPTSLKAEIDSPVAGASRFTFTNSDEYTSPKKIPVFPGTIHSPEKVKKKDPKITRSPRLKQASSGALGQSLAALSPHQGANQFGAPHFSEKPKREQSPRKFLRDTLAQYQNAQRASGGGDDDEEIRSAAHAEQRQSISFMEHHDPSTGASRVVPADSATAAAAANAATFLKTGEDAIAFFARNGSDSEIKFVHLNRADTGVAFRPYDLMVVDPDDIASEHFTMSASGLVRMSPGNPSEFIALAEWMRQSTMFNVLTSLRFFKHYLINKTFSLWCTNVRYKLYLRQRKKLLAKLYLAKETFCQPLLHVKKVMSQEVLGVVLLDLRAQKTYESSAFVEYQATKRADGSKQFELCVEKLQTIIQKVCIDVKNLTKVPDPHDEFLSDAPYGSNGGAGSGQEKTKSIVAVKSEQQQRRKLFKRAAEEAAMITDLIRLVDYIAVESLVILAVQSCREFLLELNKVPRKTGLFETTINFGEQITVFSPTCEQIQHIVISMTDDIVSTVNSVSRVLYLRPFVPYIANVVVDAPHIGSIINHSVDFQHIRKELVAKIINDYAEATEYVKIFDNVRPIYEYDKIWDFEEYSQRSHTVTTLKVDMLQISTWEKELEKMRAGQTIGILHVESRKLKQTLIPMTTAKLDAMKGLVKDLARAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLE0</accession>
    <name>A0A8K1CLE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_011358</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLE0"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW64478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="240" mass="27106" checksum="110A68C9BDADE82C" modified="2022-08-03" version="1">MATKHKYSVLLPTYNERENLPLIVWLLDKSFSENSLEYEIVIVEDSSPDGTLQVAQELQKIYGKDHIVILPRQGKLGLGSAYRDGLKLATGDFVILMDADLSHHPKFIPEFIKVQATKNYDIVTGTRYIGDGGVFGWDLRRKLTSRVANYLATVLLNPHCSDLTGSFRLYKRDVIEDIMNSIQGLGYVFQMEILVRARLKQYTIAEVPITFVDRIYGESKLGAGEIVAYLKGLVQLFLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLV3</accession>
    <name>A0A8K1CLV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLV3"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000217">
        <property type="entry name" value="Trehalose-phosphatase, variant 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF109">
        <property type="entry name" value="CBM20 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="79"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1119" mass="127002" checksum="A72D5254B046D1AD" modified="2022-08-03" version="1">MSDRLPTEREHDGKRPPLHPASFPPEKRGRPHPPADADESMERDEDEQSASGVLSDSGYSSPRQFPASRSTSTSSIGDVNAGTYTRVHLKIKAETRFGESVHCSGSSLIMGQFNPNESMTLVTTPEEYPYWTTIKPLILPRGVPHQYMYALFSGGVFNSWEPIDSERVLVPEGREMVVVEDFGVYDRETVLVPNGELSERAVVFDRKKLTEEHGEEETSTEGALSRTSSQHIRQNKLQSRYKRYTPSNYHPDPQATLYLVCYHLPVRLKKSPVDGSWSAEWNRDSLISRTEGSIAESMKARWVGCVTYQARSDSEDLSDADKQEITDILFKMDCIPVFIDRELAYDHYQGYCKSKLWPMFHNVDILDIYSSVWDRGEVTEWKEERNNGKRWEAYQKVNQLLADRVAEMCGKKDTVWVHDYHLLLFPSYIASYCKQHNKPRPTMVFFLHVPFPTSEIFRELSHGPQLLEGVLGVDVVGFHSFDHARHFLNACKRFLGLSYQSRRGGNLGVDYRGRNVVITISHVGIETIAIRNALEMHEVREAARKLREKHAGKILIAGTDVCQRLSGVPLKLLAFEQFFNMCPSWKDKVVLVQRCHLTNARDGDQEYSSNEIRELVTRITNQHGPVIDYEESTSAMSLKDRLALWLACDILMVTSVREGLNLKPLEFVFAKNPSPGHRAGVVILSEFSACCCVLNGALRVNPWNIAEVVSSLDHSLTMSDEERMGRRARDLPYITNQPAANWTKQVLSVLQESTENEEEDEEYTDMEYVDSEIGRSHVLRIGSRSDFKQLKISKVMEAYRKSKRRVFLLDYGGTIIARENMSMYVKKDFTAVTGKIPTPRMLEALSLLSSDPRNTVFVVSGVSQYNLTNAVGHIKGLGLAAENGALYSWARSVRARSLESEEASPAFHSGDRHWHQHNFKFDWKPIRDVADPILKVYCARTNGSLLKYMDQSIAWNFRSTDPEWGLVQANSLQNDLEDVLKDLPVNIIRKKGLLEIVPEGLNKGVVARHILTQDASMHRGHPDFLFCIGDDTTDESMFRTIYDYYAERSEESVHGARGHFGRSASLDTPPNSSEGSLQHVFTCTVGKKPSHAHLYVNNVDDVEELLHSLGEVSEEHEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLX3</accession>
    <name>A0A8K1CLX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLX3"/>
    <dbReference type="OrthoDB" id="62710at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="42141" checksum="1CB3ACCDC5B22C6B" modified="2022-08-03" version="1">MTRMAAAPEDVRYWRMTATDAETQSEDLSGPSSSEEDSEEYETLHPSDSKTQQILAQSEFYGKFMPSTDRVSESLLQFCSSFPVRMGPVILASLVRRFTDARFNWATKTLQSFLEVTCWVSVTGAAYSLYHDWMFALQVGTFVGALMSVCDEVVLQFVRGLARVIRNQHGGSELLEKLGFDVPKNGKAPTNGHEVELIKTLVFGFLGVVVIRSLWENFHDVKYFALLTAAAGVAFVVTAEFFCLWLPTRRVGLTLQSRFTKIRENWQDHPLRSFVELMTWLAATSYFLYKSDDFLLSLQLGTVVAVAVSLVSGLEELPTIVSSDEIGEYSVWQTRASSDPFLSVAKGLVSVQDAFIYARTAMENEAMNMYENWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CML3</accession>
    <name>A0A8K1CML3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CML3"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423324" description="J domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="28"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="37452" checksum="A28C5A9BADDC5352" modified="2022-08-03" version="1">MMHARRWTRLLLLVLLCTLSVCAARYEDPYKVLRVKRSASESEIKRAYRSLALKWHPDKNPGNPEAEKEFMRISSAYEQLANGNGGASTQQSNGRGYQQSWQQQQQRAYYQQQQYYYNQQHGARSQFTSASIFPFSLPTVLLLGLLVWAMIILPSNNTNDQQAPAGSQGQQRASQEAKASDETEKARPSPLEQLARVFAPSIFAFNPLYLTARGRRTLVFFPSDSVHGCGVREQFAMIEKLAVEYQRDPLTFCWLDLSVLPSNERTKWETQANQLGANKPFVMAFSIKGKKVVAHSASERTIELDDLRKWLTLLVGGEIAHSESLPELFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMQ5</accession>
    <name>A0A8K1CMQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMQ5"/>
    <dbReference type="OrthoDB" id="48036at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052436">
        <property type="entry name" value="LTO1_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532">
        <property type="entry name" value="GEO13458P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532:SF1">
        <property type="entry name" value="ORAL CANCER OVEREXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="142" mass="15929" checksum="9EF7F7C0007F9A5C" modified="2022-08-03" version="1">MDITDAFDEISGWEEQLIAQGEELGIEKGRELGVEEGRELGLIKGTEIGSEVGFYRGCYATWKHMIESEELKSRISDRAGKSIASFGVLIESFELKNIVDEDIMHKLLGIRAKFKVITALLGLKNDLVFSSEDIHAHKHMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN94</accession>
    <name>A0A8K1CN94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2 Aida-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIDA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN94"/>
    <dbReference type="OrthoDB" id="428576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.360">
        <property type="entry name" value="Axin interactor, dorsalization-associated protein, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025939">
        <property type="entry name" value="Aida_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023421">
        <property type="entry name" value="AIDA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036818">
        <property type="entry name" value="AIDA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28654">
        <property type="entry name" value="AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28654:SF1">
        <property type="entry name" value="AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14186">
        <property type="entry name" value="Aida_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08910">
        <property type="entry name" value="Aida_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109779">
        <property type="entry name" value="Domain from hypothetical 2610208m17rik protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51911">
        <property type="entry name" value="C2_AIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 Aida-type" evidence="5">
        <location>
            <begin position="130"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="283" mass="31851" checksum="B2E324D40322C2B9" modified="2022-08-03" version="1">MEELKTRHSTWTQRLQDAVQADGWGQVLEAVEAYEELATELTAALKEQRANLSSEQQTALRRTARALEDRARGLSSVEGDQDAPTADDMQTTLQAFRSLFAEPSSVHPLPTPAANKADGNEELEDVEESKRPLHRPPDASYLDIQIVKVGLKDAVAYVNPTIVVSVHDKDGKSMEEAKETSVGKSDGAQHIAFGKNDVIQLETSLERMQERGGAVFFEFYHYKAKKRKKSCRCWALLELDELRNASTLALELYQKPMDPKRKRINLFTVKDLFLHVQLTTQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNN9</accession>
    <name>A0A8K1CNN9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_004204</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNN9"/>
    <dbReference type="OrthoDB" id="34781at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW66439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20731" checksum="E910D7B2EFCE7AD2" modified="2022-08-03" version="1">MGMAFSRVFERLFGKKEMRILMVGLDAAGKTTILYKLKLGEVVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYYQNTQGLIFVVDSNDRDRVDAARDELHRMLNEDELRDSILLVFANKQDLPNAMSAAEMTDKLGLHGLRHRQWFIQACCATTGDGLYEGLDWLSATLQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP32</accession>
    <name>A0A8K1CP32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="8">PARP</shortName>
            <ecNumber evidence="8">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012248</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP32"/>
    <dbReference type="OrthoDB" id="2017365at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.142.10">
        <property type="entry name" value="Poly(ADP-ribose) polymerase, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004102">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036616">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02877">
        <property type="entry name" value="PARP_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47587">
        <property type="entry name" value="Domain of poly(ADP-ribose) polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51060">
        <property type="entry name" value="PARP_ALPHA_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WGR" evidence="12">
        <location>
            <begin position="146"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PARP alpha-helical" evidence="11">
        <location>
            <begin position="300"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="10">
        <location>
            <begin position="437"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="692" mass="76534" checksum="98E3BC1CEAA4CE6E" modified="2022-08-03" version="1">MKTMPVLNTLVPEPLACRHSTNGRTSVMSKKRRVSPPAMGVVLSFIGATGTRSKRKAVAVAAVSTVPASDPPVLSPAEKKKKKGRKPSGVTASRRQQLARALGTGLLSVDERTEDEDDEYELLEMKPTPRRIVRPDPSLPGEYQGRVSVVEYQGAVYDAMLVRASVPQHSSEFVALQVLQTDDSGEFFVWTRSGHVGVTEQTLLEGPYYTRQEALAQFNALFVSKTLRSWTERDSIGYSEGSFTYIEIDHSSTEEDDSIVAVTATRKRRRSSSSSASRVKTIEQLSVHVDELPSHVRTPGSRLDEDVQSFLLMVTEAAEYEARAMYGVKQSHAKSTRSSSHISVALPLGRLSRATIMRGYDALHQIYDAIKCRADRTMLTHLSSRFYSVVPHSSPLEVIDSMIKLGRRVELLAALAVRLRREDAQSLELTQRLLAKNYLDECYDSLQCRLFPLSTSSHEYQLVDSYIFNSFCCYGTVHATTPSGSTGLSRHCVSNGKILNVFRIEKPSEAQRFEPFRAFPNRRVLWHGSRLGNWLSILTHGLLIKPCGVPHNGSAFGNGIYFTDKITRAMAYSHFSGKPGDRRQVFILSEVALGSCKQIANTSNAALSYVHHTSGGSARGSKAHHSCHGVGRCSSDTTGDYEDAFGAVWPLGKPTPAKEIPTSTLIHNEFVVYNPAQVRMRYIVVATDLGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP63</accession>
    <name>A0A8K1CP63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP63"/>
    <dbReference type="OrthoDB" id="9942608at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040192">
        <property type="entry name" value="CUEDC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13467">
        <property type="entry name" value="CUE DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13467:SF3">
        <property type="entry name" value="CUE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="30462" checksum="9CD8B55E79823F8D" modified="2022-08-03" version="1">MALSYEEGMTTLRSIFPTWDAQVLAELLEANDGHLENTIDMALTMEPPTQPTAATASPRAQPRRSPRSSPRAKTPATQTAPRRARVTLPDDFLRLPSDDGDAFSTRPMTEQEKQDAMLARMLQDEIFREQLFEDEEFSAHFHQDPRRGASTRYATERSSMSREKSASEIASETFSAMSVKFNSMSEAMKKKAQEMYLKFQTRSDAPSERDPKSHRPLMAEDSSDEEDERTYHGTADLRHRHMQESSRDSFGSRFPDSGLSRRGTKKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP66</accession>
    <name>A0A8K1CP66_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exopolysaccharide phosphotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP66"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047141">
        <property type="entry name" value="Stealth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031358">
        <property type="entry name" value="Stealth_CR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031357">
        <property type="entry name" value="Stealth_CR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045:SF0">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17101">
        <property type="entry name" value="Stealth_CR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17102">
        <property type="entry name" value="Stealth_CR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR1 conserved region 1" evidence="5">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR2 conserved region 2" evidence="4">
        <location>
            <begin position="112"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR3 conserved region 3" evidence="6">
        <location>
            <begin position="265"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="55959" checksum="F1ACF868B5C769F8" modified="2022-08-03" version="1">MQSPTAVRLRLALTQRRHLPWILVGAIAAWFLVVYMLHAMPTGSTYDTLTDTEAQQYGDAEMAEMFPGKCKIKNFNQLRRMSIVYTWVNGSQPCYREQRIKHGGKNAVGGSRDREIGELKYSIRSFKKFVPWHTGPIFIVTPGHIPEWVDLNNPRIKVINQDDLFPDYAKSFLPSFNTHVIEQFLYLIPGLSDIYMQINDDYIFTKPIEPHEFFTCDGGIRLLHENGLISHVPPTPKKGIWISSVLNTQQEMDLRWGKKDRHFIKHAPFVYSRRAFERVHQIFDRPLYMTLKSKFRGKPDMNMPLLHHYYMMSQGSQELGIPIYSPPQEEMQGYKLVLMQNDNIPQLKETFGQIIDGTTPYKIIALNDEYSDMAVADTAIDFLGRFLPEPTEFELKPGAEPHPLTIRKAGSCEVDDTILSPFPRRIEASQKFQVVAYREIRWVAFTTSLLKGLGMGLGVLIAYVFYLLVLRRNHATTGGSMAAYDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQG6</accession>
    <name>A0A8K1CQG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQG6"/>
    <dbReference type="OrthoDB" id="72070at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="59799" checksum="8547C29220DDF999" modified="2022-08-03" version="1">MDTLQSVFPSVPRAALQRVLEICDQSVEAASSWLIENDWHELVDDEEDEQQAQEEVREVDNQRAVNGDQRQRPTVAQTLPSANAAFVGTTVISTSAIAATYGNSNGTPTAPMASMALNSTSTARFGMNGREGHHGLFETARRSNGATRFHHDLDGDDVESEDAEDDDEDEEEDDDDEDDDDDDGDANSYYDSGDEAYYHNSVPHLTKRIKVTQDDKPRDAKSECFWASFDDQTMSKTLIELLNTTLSKVAHSKVTLLNKTSAHLDEEEATIRLKSILVRAEEESRPQLDESRNSNPNLGNSLRRILNSSPSSPVNGADSPTIVAGQKRKRTEDESSPIETLGFFAYFFPITDLDMIWRSIMHAHLFSRRFGELIEFHTSGCFNRRDFDEMMHIHTTVSSSSSRAASIGAPLSGLKCCVLIPCEASDAEIFRVGKNVHTTLKLPGSLYYRALDVSDKSSSGRERALPDLLSEDGILTEDSFRRFARYRIKKEEADANTKTAKDSASSDHFLGYQRQHRVEHCLQALENNAWTNRLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQK1</accession>
    <name>A0A8K1CQK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQK1"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="76"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="665" mass="73336" checksum="68FD48F88C1ABEB4" modified="2022-08-03" version="1">MGGTCSTAELAMSSIDFDSYKGIRYTEEVPNSREENRGPIYLAKPINVDETKLTLYENLLSGVSLENGNRRVYGTRRVVDGQPGEYEWITYKQALERSVTIAAGLTKFAGLKRNDLVGIFSKNRVEWCLSSHACDRMTYALVPLYDTLGADAVPYILNHTQLSTVIFAQEQFNVVLECKDSCPAVKFLVQYEDVTDEQRQLAEEKGVEIKSLQEIEALGKANPVPADPPAPEDIATICYTSGTTGNPKGVVLTHRTMAFLGVLTQERLRLHKDIVHISYLPLPHVFERAVITAMLNLGASAGFYCGNVLTLMDDIAELKPTIFVSVPRLFNRVYDKISQRVEAAGGIKKALFDQAYAGKKAALASGQKTHAFWDALVFSKIRQLLGGRVDTMLSGSAPLSADVKEFLTIVFGCDVVEGYGLSETAAGLTLASADMPLGPHVGAPLPNLEVRLEDVPEMGYTSNDKPRPRGEIICRGPIVFGGYFKEPDKTSEAIDEDGWFHTGDIGCWNADGTLSIIDRKKNIFKLSQGEYVAAEKLEGVFAKSKFISQIFVYGDSFQNALVGVAVPDPDIAEAWGVSKGRSKEDSTMDKLVHDAEFQTEVMADLVSIGKEAKLRGFEFVKKVHFHPDPFTVDTGLITPTFKLKRPQLKEYFQKQIATMYAELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQU6</accession>
    <name>A0A8K1CQU6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQU6"/>
    <dbReference type="OrthoDB" id="414039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="678" mass="76610" checksum="AA85855270BAEB3A" modified="2022-08-03" version="1">MELSTAEGALRTLKFRPKVSTNAVETSSALLAVVQALKTPAEAAQDVASLHDQLAQGLTTLLLFGKERWEPLAVFNVVVRDLLHSHFDGEGKQLPFTTEFLTVTTFGAVRDYLEHWEPRVRMSVAKLIGALARWDLVWTTQKCTPLIVDSVLCNLTRSPDFEETGFDEADDNISVNGMESPTGSTQGTPRTPSTPYRLDDVSGWKALESSLSALKYVIRGSGAKFLTEKTVDGAFVYFTPEIKELATTKSVFHINRHVRVVGLDTVTALCEVAPVGFLDSHREIADLFCKCIVRGMHDNWSQVRYAACITTRAFLTKLQENAREDYYGQLVPRICLNRYYVAERVQHHSQETWRMLMGDRGRAVVARYAKEITDYYIEMTDHCVREAACHSIAELATKVDKEAIRPYVPGLLDALLYSFRDNSWLVRDAACLASSQFVLAFPTESRDVLEQLYELWIEHLSDEIWSVREDAAIALGNVIRAYGKEAEERVAKVAEDFIQRAKTQPAMSHHDHEEHMRSEKKHMSKQAFSCCSFEPKTDERHEHREVQPWEHTDGAIYLVRELCAVAPEVGVRLLPLVADVAILRHFPQTATLQETVWKQLPLMCEALGKRVFKQYLELFLDPMVFTLQGSNRLARFAARDCVAHLSKLIGPNIFLGRLKANPTWVEAIAPVVPQQPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR96</accession>
    <name>A0A8K1CR96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007811</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR96"/>
    <dbReference type="OrthoDB" id="201398at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000538">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="44"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="125"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW68139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="231" mass="26662" checksum="4DAFFB11232AE882" modified="2022-08-03" version="1">MADLYAEIAEEEERVARGQQQRKYWDRKTYTSYEEQQRAIASSATLYIGNLSFFTSEVQIYELFSRVGNVKRVIMGLDRFKKTPCGFCFVEYNTHEEAVACANFVNETKLDNRVIRCEMDGGFKEGRQFGRGASGGQVRDDRRSRDDYDPGRGGYGRSSDTNHFRRTTGPRKRSRGDSMTDEPPRKQERLSPPPQDSKDEEEENPRFRDREKDDDQDGDEADEAMGTAEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC2</accession>
    <name>A0A8K1CRC2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="19293" checksum="C17C7B4B7CAEADA3" modified="2022-08-03" version="1">MAKTNLNTLVLGVVKMCENEAKEGNLPVAGSGSLDTGAGSLSLNDTASVGDLPISTEEEDAKIKELGDSKEREKACGKPGDDYTNVRDSPRCSRPECLAYYKDTYLKMMPDCRDKAYMKLYIARCEAVPETAPAPSSSTTTIPSLVVTGIVALTALLGRKEKPHEMLFIASKPGCGQAQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS67</accession>
    <name>A0A8K1CS67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006043</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS67"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="66"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="558" mass="60380" checksum="AA99F6B60FAAA2BA" modified="2022-08-03" version="1">MMVGRCMVRGGDTMRILTSARRPWRALAVRHVTASRPSVRGVSDWCKKSLLEAAAALQNGQVTATELTKACIDQIEATKRLNMFVWTDYDRALQLAKESDERRANGKALGTLDGIPVGVKDIFCMEGVPTTAASKILENFVSPYESTATHKLLEQGAIPVGKLNMDEFAMGSGTLYTPFGATINPWSSDFEENAVVAGGSSGGSAAAVASGCCFAALGSDTGGSVRQPAAYCGIVGLKPSYGRVSRHGMISYASSLDTPGIFARSVADAAIMLKAIAGSDDKDSTSIQSEVAQDWLNTVTQSSGRTDLSGVRIGVPEEYFVAELPEEILQVWDRGVQWLRDAGAQVVSVSLPTTKLCIPAYYILACAEASSNLSRYDGVRYGYRAKDIGFKSDGDQSDALHDLYCRTRSEGFGEEVQRRILSGTFVLSAGAMSDYYERGVIIRQKIREDFERVFKELNIDALLTPTTPTGPFLINDKKTKDDPVGMYLNDVMTIPANMAGIPAISVPAALTTTGDLPLGVQLMSARKDEEKLLEIAHSLEEHASFHKYVPERVYHTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC8</accession>
    <name>A0A8K1CSC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006147</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC8"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="9">
        <location>
            <begin position="33"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="10">
        <location>
            <begin position="394"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="758" mass="85892" checksum="980CBD99EB89896D" modified="2022-08-03" version="1">MLTTSGTPPPSALFAWTDALQELIRPNNVPLLGLNASERPPIPTNDWWGNLLAWKANERDSDPIFANPYVYLLAKDRGLSLSYLHDYRVDGPVNENDAIKYYFYPATIKNLVLSATEWTPSTGVQMEIQSWDDMGVTLSLSEKATTPHTSVARYAKTYLSMGNAFTTMEYRDLHAQLQSDHGILTVNNVPIHENQVVTGESFVIEFNNGHKWLAFYYPDNQVMPGQRGVQLRMHHNTLITTAPFTGILQVTYVSSTKDHGVNEHAILDLYRSAAGVYPVATSLFVQDADSFGYEWTLRDAQQGEACRSETHLHFALRHLQQMMDTSYVIKKPELALWSHTRGIMQAYTIRATGDGKAQWRFHALQDISAAVDSQATSFLPRGRLSAQDVQELRLVDILTQEIVHADWNAAIPHEGSYYFKGKSLQKFGSMVLIAKELAETTTPELTSVWQQGLQKYRVLLEKFFKNRSAFPLVYDTLYKGIITSEPFKRRDLNVDFGNGAYNDHHYHYGYLIAALAILLHLEGDQAQPANAELRVFVETLIRDVANADPKDQYFPRFRNFNWFLGHSYSHGVTPMADGKDEESTSEEINFLYGLALYGHVTHQQSLTSLAKLMLKVNTVAIRTYFLMTDDSTGIHPPRFIKNKVTGICFDNKCDYATWFSPNRECIHGIQMLPVSPMLDVVRSRAFIQEEWEQILAKLDCVQHWDSRGSGWTSLLYSNAAVLNPDRACEVLSHCPMDDGLSRAWALYMARSKRKGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTG9</accession>
    <name>A0A8K1CTG9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTG9"/>
    <dbReference type="OrthoDB" id="421327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="52086" checksum="CCA033C3AEF76551" modified="2022-08-03" version="1">MALLLASCVRRAAPGATLHTRPLAASLVGHAQAQSIVTTPSGRASRRSRRLRRTKGDADDQSISSRLSLMRENMRIVSNIGDIARTGLTNRVEMPQEMLDRLTAIVKRRTHSQLMHLRENLLQQEANKESTVPLDMHKRPLGWTLDKDEQIQPYLYGPNETMVYLAQDVEMTYACAHQAFRQLQAKRPKFAPMSMLDFGAGPGTASWVAKDFYGESLSRYRVLEPSQSMVDAAEVLLDGFPGLSVRRSLAEMKREIQNGLRYDLITVNFVLSEITNDYERVAIMSALWELLSDKGVLVIVDRGSTWGSHQVRSARQFLLDCVAEEENENAKILAPCPHQFECAAKGNTWCHFVQRSPRVQYPRDATTKRWHGHKVSKFSYVVMEKREGKVDETPEPLARLIRGPLLANRHVHLDLCMPDGELERRAVTKGKSIREAYRAARKAHWGAQWPADASIYTEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTJ5</accession>
    <name>A0A8K1CTJ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methionine aminopeptidase 2</fullName>
            <shortName evidence="8">MAP 2</shortName>
            <shortName evidence="8">MetAP 2</shortName>
            <ecNumber evidence="8">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001450</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTJ5"/>
    <dbReference type="OrthoDB" id="7848262at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="11">
        <location>
            <begin position="126"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="451" mass="49866" checksum="8211B912E48D3BBE" modified="2022-08-03" version="1">MAPNDLLDVDMTTHDPIHQEETLDAVPTSPSDPQKTKKKNKKKKKKTKTHPVGSKLPPFRGVTGYTDSYVSVGQTEPPTIPVAKLFPNGNFPIGEIQDQPGDFNTYRSTSEEKRALDREMEDLYNTMRHASEVHRHVRKFAQSIIQPGIRLIDMCEQLENKNRELVQEAGLGRGIGFPTGCSLNHVVAHYSPNGGDNTVLSYGDVMKVDFGTQINGRIIDSAFTVAFDPQFDPLLAAVKAATNEGIKQAGIDVRLGDIGAAIQEVMESHEVEINGKVYPVKAVRNLGGHTITPYEIHGGKNGKSVPMVKTNDPTKMEEGEVYAIETFGTTGRGYVVNDGECSHYSVVPEARHVPLRYPRSKKLLSHINRTFGTLPFCRRWLERDDGGSAFINPNGAKQEKYLMALKELVNSGLVSEHPPVADIKGSYSAQYEHTLVLRPTCKEVLSRGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTM4</accession>
    <name>A0A8K1CTM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="73"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="205"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="339"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="372"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="438"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1650" mass="183953" checksum="A3A171D35F3C935B" modified="2022-08-03" version="1">MDETVEALVEAATDGQLDEVERLLDGDDAKSLLEAKDKEVGHVVLHGACEGGNLSLVNKLLAFEVDVNALGPNDRTVLHSACESGKTDLIRRLLDLGLDLAATDVNGFTPLRYACNRGDIAVVELLLAEGADATVLDKEGETLLHTGCRGGLDVVKLMLKRGLDVNALDDYGRNALHFAVEGNNLDVVKYLMEEHGLDVKSVAKNGMTMLHSACMGGSVEMAKFLLACGLDLDAEADLTMGQNGWTPFRFAIETNNIELATYFSMASELTASEGDKKDALDPAGVNESKALTRTTSTIDTTTVDKDGWSALHTAAKSGNLEMAKLLLSLGVDANTCDKDQWSVLHTAANTGNVAISCLLLEHGANAKAVDKDGYSVLHCATTSGNIELVEMLLAHGADAFAVDVHGLNILHISAVMGFPDMFEFFIRIGLDVMARTENGCSTIHLVTNIHKHEAINLLVERGLDVHLRDNQGHTALALCLQWSPDEDDFAAVLQTAYTLMSNGAVFEASPDNYPQVGEKNRDQAAIIPICVDRWTEEQRRGKKNLTQIPPEVFVRGPKAVQTYLDEISASSDSDLVLRRKVCVIGSSKTGKSSLIRSITTMAPTLVDIEDRTIGVDLFSLDFTEASDEGEPAKNHQITIWDFAGQDEYQVAHTLFFSRRTLYLLCVDTEAFGQVVDESRECDDEDEAEAMIDAFVKDRVWRWFRLVFLRQPDAEFVFVATKVDAFGGVPERLKELEDMMMDILGEYKASFDEEVNQETQALQDKMVKMSYGLTDNSVNTRVRHLERMRTRLNESLPTSWLAVDVTKANSIHDARTLIERVVTQSDRSFLMPDKYSRVLEMIKELRVEPPHQTTKARIKQIIVPLPELREQLVQGVNNLEPEDCETILETLHDLGDVLWYDRDGLGVLGDTVILSARLLIDLVRQIICHDPIKNVKKTRTSARVAKLVENMLLSGQVPHELVTTFTLWKSLEYPNQMQRFKKLLQHFQLAYPANTTSMETDSDLIVPTFWKLREDQLDTLDLEPLGDKFRSSLAQDAAASIVRVFHWEYDFHFEMVETIFEQLVVQSYSVFSKRTAYRSCVESIPNPHYAIRLSLVKEDGRQIISLEIAAADTMIAEEYLRELYQSLEAVLSDYPGVAVTRYGVDEDGGRERIDQMVDLMRRSSPGRQVVLRNEHEWFPENLNWYKLPGERDTSASPQSRLEKARAIVEVFLARKHLKETRPSQSWQKLLTRVSSQLSGRSMKTEQEEVTFQLPPQLATLPGGSFRSEMKAFVKDELVAMQTVLMENMGMVGNKLLQTSAGDGNHRDLPALWMVEYVQKPKARLILWILSEISGRCFHKPIEIAVSRQFLAKHGDKIQLGLSIFSSVLPDAPVVSVVKSAIDMASPILDNELAHARSVHDLLGNLGLENGGALNTSKQRPVSPAGMYGLLRALLKIHDPDFEPDKICDLAKLECGMVLQEGGYRWAHRHELLREPELYKLRVNYASDSVHSVVSSHVPSQADIKSGSEVEPLYYLSDFRASGLVDDEARLAYCTWELVNRAQSVRIGGGETIQNPYEGPVESWWQEAFVLSDVKAENDLSECELVVEVKRPSKLILRSDRFVGRGFIMLREVLSSGTKLTESCRFVIPLTKNDGSPSSGTVECQLWGSGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU93</accession>
    <name>A0A8K1CU93_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU93"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF22">
        <property type="entry name" value="SLL0786 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="153" mass="17358" checksum="D312429F8BA3E26C" modified="2022-08-03" version="1">MPLEVTRVTANEGFEIAKRLRYEVFIRGLGFDPKVDDDEYDFLDTTVHLVGRDVETNEYVAVIRCVVDPVKREGKVGRVGVLTKFQGKGYGGVLIEEVHRVIKSQCDTVLLAARPEKVGFYNRYGYARTSDETFLDDCGLDLCWMAKNLVDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUA1</accession>
    <name>A0A8K1CUA1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUA1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419464" evidence="1">
        <location>
            <begin position="28"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="20188" checksum="1E76F9AFA1FE75CB" modified="2022-08-03" version="1">MVQIKSTISFCLLAIALTASNLQDAQAEQMTFGGGYGGYGGQSLRGAGASGYGGANQYNGGSVHGGASGAISGNIGGGVSGGAGLSAGAGIGAGINGAIQAGLNAVGKIAAGIGAGVNSGGYGGYGGKGSAQAGAGIGGGASIGGGIGGNAGAGIGGAAGAGAGVGAGAGAGASIGAGANIGAGAGANIGGGASGQIGGGVGIGAGINAGAGIGGGANAGAGTGGQYDGGAATQKGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUZ1</accession>
    <name>A0A8K1CUZ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUZ1"/>
    <dbReference type="OrthoDB" id="184751at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="17843" checksum="7F4A450757401A09" modified="2022-08-03" version="1">MPSDTPLHKAAHNGDKGACLQILDEKSVDVNAPGAGDRRALHRAAGGNHAELCTLLLDRGAEIDGADKSGRTALHWAAISGHKEATLVLLQKGAVINAETTTGMTALHGAAEGGKVEIVRLLMEWKADSSKKDANGKLAFDYAMDGKHKAVVKVLKEMGDAAAQSASCVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVL1</accession>
    <name>A0A8K1CVL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001909</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVL1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001669">
        <property type="entry name" value="PRK00432.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="7"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW69753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="156" mass="18009" checksum="900FB92219A2FC05" modified="2022-08-03" version="1">MTSETEMQIFVKTLTGKTITLDVEPSDSIDNVKQKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKNYTKPKKIKHKHKKVKLAVLKFYKVDDNGKISRLRKECPQCGAGTFMATHFDRHYCGKCHVTYQFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F987</accession>
    <name>A0A8K1F987_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F987"/>
    <dbReference type="OrthoDB" id="123000at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW54975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11739" checksum="9114291AF92EF1A6" modified="2022-08-03" version="1">MDRRGTGRSALLKCEAAEGYSAGSPGGVGIDFSEVANCVKDVLYQIEGQTAAFSVTSAAKDVELLTRELNEEDDVFVYGASYGTYLTERVMHLAPANIKGYIRHHKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9V3</accession>
    <name>A0A8K1F9V3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9V3"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="579" mass="64381" checksum="EC8397B2DA4A4C4A" modified="2022-08-03" version="1">MAGAAPTTAPYAPPEWGVDGSNAFNIYMDVIKGGLVVESLTLPPDASKSFVVAGRMEPVCDLVLQHPSISRVHAVLQFDIHGALFVKDMNSTYGTFVNKKRLVPNQFERLHIGDIVVFGESTRMYALCGPAELLPEEYDSANLQAFRARLEKKQNEARSMGRREKPEEESGASWGFGEDAEEEDDEDSDEEDKKASHKGRGGESDLPSYLRGLKERDRAYESSVKASDVSEKDQKLFQQLQTKIKKMENLETEKSRILAKQNDLQGLSEGQEMTLERNNARIEALQKEIESLEDQLHARNAQREKSRSAVATKKKTTRKEDARYDYDSDEDDFYDRTKANQRKQQERLQVPGHQSGVAPVKASAPQTLTAESIQKTISELKKELAAVVQECARAASSEQGESKTEDEVDALDAFMQATTQQLQQSERVSLETKRKELEAQLKQQEQLLAIAMPALAAVPTPTPTVMEKVASPPRQEATTPVQKESMEPLDAEKTRERAPPVPERTQEKVVKKDLAPVTAPADEPQPKKRRVMGPTLPPPPSSGSYRSTDGELEGGERVWVPPSNQTGDGRTALNDKYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FA98</accession>
    <name>A0A8K1FA98_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FA98"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000009">
        <property type="entry name" value="Carnitinyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32368" checksum="29A8F3B524AE573A" modified="2022-08-03" version="1">MLMRSLRVSRVCAPPAARQALTKHFPRALHVATGDSTKQFQVQLLDGEHEGVALFTMSRPEARNALGKQMMIEFREAMDQVRFDTNVRVVVLQSTVDKVFCAGADLKERIKMTPQEAAATVFGLRSAFTELEQLPMPTIAAIEGAALGGGLEMAMACDFRIAGAKAILGCPETSLAIIPGAGGTQRLPRLVGLSKAKELIYTSRRIDSMAAERIGLVDYAVPHSDALNKALELAREILPNGPIGVRMAKEAITKGLEVDLATGMSIERACYAQVIPTKDRMEGLQAFKEKRKPSYKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAK0</accession>
    <name>A0A8K1FAK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAK0"/>
    <dbReference type="OrthoDB" id="271064at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030378">
        <property type="term" value="F:serine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018114">
        <property type="term" value="F:threonine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070179">
        <property type="term" value="P:D-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000007">
        <property type="entry name" value="L-threonine dehydratase catabolic TdcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050">
        <property type="entry name" value="SERINE / THREONINE RACEMASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050:SF1">
        <property type="entry name" value="SERINE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="23"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="344" mass="36829" checksum="C821C272E582922C" modified="2022-08-03" version="1">MTETYAISLESIQAAAERIRGLAHRTPVLTCQTLDDMATQARGMEARMFFKCENMQKIGAFKYRGALNAIKKTLETQGAQNADEPLTFLTHSSGNHAQAVALAARDANCRAIIVMPADAPIVKRNAVAGYGAQIVPCGPTIASREEVAAEWATRVKSHFIHPSNDPDVMSGQGTAGLELLEQVNEQWATTLDAVVVPVGGGGLSSGVAMAVKSMNPSIKVFGVEPAGAADGLASFRARELRGHDTPPQTVADGLRSVLGTKNFPVIRDHLDDIVLVTEEEILTTMKLMWERMKIIVEPSSAVTAASVIFNKLPLVDGERPIRNIGVVISGGNVDLDNLPWVVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBY3</accession>
    <name>A0A8K1FBY3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBY3"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
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        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="8">
        <location>
            <begin position="41"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="37163" checksum="EAEC6EB472578B95" modified="2022-08-03" version="1">MACTDQLHVRGFSSSRNVAKIQSTPHLKRKLGQHLLINERILTQIVDAAELPALLAARQKEDENAVVRVLEIGPGTGNLTSALLNLSPRVHVHSVEYDERMVERLQERFGSEAERLSIEQTDFENFEFVTKEGDERVRHLDACVANIPYQLSSIIISRLTTYMHRYPERMQCAVLLVQEEFAQRLLAKPGSQNYSRLSVNTALVADVESVVKVGRNHFLPPPKVDSRVIKLTPRLTTEPLVGDDGEKLFFQRFDTLLRIVFLRKNKTLRAALLTSTATTLMEKSAQALSKEERTIRVEEALEASGLTTKRAVQLPVQDLLWYVYFQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCF5</accession>
    <name>A0A8K1FCF5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCF5"/>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="12150" checksum="BF27510C1EDE0713" modified="2022-08-03" version="1">MTLSPPPPAHLKDRTEFSITLHVPTEPVGVTFRYEYRPVGSEWTEAKRIDTKSGDSEVVLDDLMPTSSYEIRIYAVKKEGETEEVSAPSEVAAVDTEVPGCTPEPKCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCK6</accession>
    <name>A0A8K1FCK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008567</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005108">
        <property type="entry name" value="HELP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03451">
        <property type="entry name" value="HELP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2291"/>
            <end position="2309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2321"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2363"/>
            <end position="2387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2439"/>
            <end position="2458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2478"/>
            <end position="2496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2682"/>
            <end position="2700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2720"/>
            <end position="2743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2755"/>
            <end position="2779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2785"/>
            <end position="2805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2812"/>
            <end position="2832"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="550"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="900"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1238"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="2028"/>
            <end position="2059"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="2554"/>
            <end position="2589"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="2590"/>
            <end position="2625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2839" mass="310451" checksum="509514B70312CED2" modified="2022-08-03" version="1">MGNALTSAVRDPASVALVEAVVPFDNLHVHEVEAYWRHFYDQATSFALTRAEFRAICTKTACFLNPGVSTHRVVQDADAAFKVFCVRHSYPLEGRAVVAESELMDALEFLSVIAFIADAPIEDKIDLIFDSWDMSEDTALDVEECTISLKSTLNGLTKALRPVNERSTDKRTLALMDDEDIELLAERIFREIAKVASSSSLNQITINSDQFRAYCTENKTARALFDLFHSAKSEQNPSNQDEDDESIDPNDISADEARRLAQKIEQGQEADSKTAGEESFSAQTEDPGDEFLAVKPWKGAIVPPTKVPALDKTAPVIAISLEWIFGYCAQDTKNSVRYGHSGSGHQDEIVYPAAAVGVVLNTKMMKQRHYLGHTDDVLSICLHPKQHVVASGEIGKRPKICVWDLSTQETLCVLQGFHQRGVLLLAFQQDSQLISIGGDDDHSIAVYESKDGWKSAVLKVSSKGNKAVPYHLTANPSSTTLDFVCCGEKYIDFWTSDGKMLSAKKALLGKKGNQQPFLVAEYLGSSGSVVVGTNDGHLYHFGGRDLSSVIRAHGSAVNALHFQAGSLVSGSKDGQVSVWSDKLKLLVGPFDVKDTVLGSRPMYYNVRSCCFSHDQKTILFGTLASEIYEIDAKTGKSVREDALVKAHFQGETWGLDTHPHKAQCCTVGDDHTLRVWDLERHKELRSVALDLPARCCAYSSDGKMIAVGFGDGSNVNSKAKSAAKKPSGGFAVFSEADLVKVKEPNYEPKKWVSDIKFSPDNRVLAVASHDTTVYFYDALKGFAKKHAFKKHTAYVTHIDFSSDGHHLQSTCGGYELLFSEVKSARHMINASSFRDERWNTMTSTLGWAVQGIWEEGSDGTDVNAVDRSKDGLYLATGDDFGKVKIFRYPCALEKASSVELHGHSSHVTNVRWSSHDRYILSVGGNDRCLFVWRHEKPDKMDYGLTGLDRDQGRVAAPVLDDVVDTRDDDPLDVLATEEDIGDEFMAVKPWLGAIVPPSDSKSLKIINSAPDTRLELERVHGYQGQNASNNALYDSSGKVVYHAAAIGIVFDKTSQRQAFFKHHDDDIMAFCAHPNGTTFATAQMGKKPKIYTWNSNSPASSISCLDGFHQRFVSTMSFSLDGKKLGSVGGDDDHSVAIYNWQNGILVASAKGERSNVLAMCFHAEQWITCGDKHVRFWREQGKNLTSKKAIFGKANHKDGRMPGVFESVVSFGANAVVGASNGDLYIFQSSNELSKIVRGHSASLSALYASTSGNELITGSKDGSVKLWDSQLACISAFDLKSHAPSLQVLNPAIRSVCLVAGSRSFGTLLIGTAGSDLIEIDTTRSTPACTVITRGHSELELWGLACHPTRPEYCTTGDDGVLRVWDLHKKTQLRAEKFGAMARACAIFHGDTLDVIAVGLGGRHAANARNAKAQAKTGTILLLSYADISKPLFEDKPSKQPISDVKFAPNGSVLAVGSHDHNIYLYAIQDNFKKVTKAATFSKHTSYITHFDFSADSRFLQSNCGAYELLFSDPATGKQITSASSTKDVKWGTWTCVLGWPVQGIWPPCSDGTEVNAVDRSAKGDLLVSGDDFGLVKLFRYPCVTKNASSADYRGHSSHVTNVRWAVSDTHVISVGGNDRCVMEWKVCRDNEEPSAEIAEEIEIEEAAEVEESIDEPEGDEFLAVKPWLGAIVAPSNAPTPNTREPDLHIDLDWVYGYHTELSKQNLMYNSYGEIVYHTAAVGVIYDAQQHLQRHHQCHNDDIMSFTMSPKRNVVATGERGKRPVIRLWDAHTGVLLSEIKGAHARGVVSLAFSSDATKLASVGDDDDHSVALWEDSSHGAWKQPKAVAAAKGDKGVNYFASFGSGMDSLVTGGAKHVLFWRVEGKTMQSKRGKLGKTGTLQLFPSGCGFGDDFVTGTASGELYVWRGDTLSKAVKAHDGESTVVYAQNVSTGRDSSLMLLSGGKDGRIIMWNASYQCLKMFDLGSMGTGCLNKALCSLSLDSNGRKILVGTASSDIFELEVASETVLNGGKPVVSGHFALELWGLAVHPNAREFTTTGDDATLRTWDMDTKQLLSVTKLPTKARACAYSPDAALLAVGLGGDNGVRRKGKAAKSKEGGIIVLSTSDNKIVFEDQPAKEWISDVKFSPCGQLVGFGSHDNALHLYSCRDTDLKKRKPFAKHSSYITHFDFSHDSKYIQSNCGAYELLFCDTSTSDQVRSATSVRNVNWATWTCTLGWPVQGIWPECADGTDVNSVCASSSRTILATGDDACKVKLFRYPCTIKGVMRDEMATRTMSSFFIDPKDLPQDGYGLSQVLFLGAVYGFVLFNASNMISDGSELLLLVPAMAGIVGSVVLPVLGAVPDGAIVLFSGMGPNAQEQVSVGVGALAGSTIMLLTIPWALSILAGRVNLDEQGRGSYIRPKNAPEGWSKLTPHGNMNLFKTGVVLFDEIRSNARTMIVTSLIYLILQIPAFQYTGTHARDAVADHEAVAKAERPFAFVAFVVSMAAFFIYLYWNVKRSSKVAEDVIDEIRVQAIRNGEISLSGVLSAELVQMKRAKPDSSTALNPRALFENVADIIRPFFHAYDKNRDNRIDADELQFFFKDMGETITREEALHWMKEADKDNSGFVEFNELVEAAAKYLVAKYETEQEGRVVEMKQIHVEVPHTDLSFANNDDDEAEEDEEIPEDLAHLSISEQQRKIKLRAAYLMFVGTALVLIFSDPMVDVLSEVGARTGIPAFYVSFVVAPLASNASELIAAYNYAQKKTSKTISISISALLGAACMNNTFCLGIFAALLYFKGGLVWEFSAETIAILMVELVMGYFAMKKTQRLFDGLIVFLLYPASICLVFFLENVIGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD85</accession>
    <name>A0A8K1FD85_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="54"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1111"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1768"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1846"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1909"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="815"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="862"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1239"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1443"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1570"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1686"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1888"/>
            <end position="1910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1247"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1443"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1484"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1535"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1897"/>
            <end position="1907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1947" mass="216403" checksum="42454CA7D6599F94" modified="2022-08-03" version="1">MDIMMRLEGAGFSAIANEFHQREKRLGGGLPLHDFVEIVLRGLPRPRSPEEKYASINALVDLFEDIDINGDGTMEFDEFTSFCVDAGMVATRLQATKLKHRYVRQPKHMIKTMNGCVGIEKIKWSAQFQRFLVIENTAKSVKLYSVDGKLVTEVRPQSTLQAPVPDSPRTNGDAERKDATGRSPRRRSEHTQDASTTPATASTVTGQSGIFILDAAFVHKYQCLAVSTTDFVISFYSMDEPKHQLAAKAFSSVIIGPTYDILPKLTMITTTAQLTLRFCETAGLLFSTGNDRVVNVWKIMDRDTKILWKRLLEHRDMVLDILEIPEHDLLATCDLHGSILLWDINDCRPRGSLVGHTHGVKQLVYSKDHDLLLSAGFEFDAFGWDVASRQVVMKLAGHRAPLIGIQLTQFHTERAVTADSSGVIKLWDISRGGNGAISIAASSSQKQSGGRGASQAVLLESIDPSHSLSRFEPTTFVSLHPQRRDLWVAAAGSATLHLFRSVRVQQFDEIPLKAFYNYNANRFIVVCGPVCSIWDGEKGSCVDECQQIGASIGFSGGNSRESSNGDAGGRSKRSAVASSSMETPSTTHNGMGATTTESSSDILLAVQDTKCKKLVLLSEEGDMGVFNSQNLIQMRRCREKFHGVRDPSISSMAQDGLAPSCGIVGLHYCSENKLIIATDAHTSAIIVIDDSNHDLAKGIQEMSVLRRLTHIPGGISASAYGYHASMIATIDEATSETISVWDFETLMLLSSCHLDETERATGEDSTLHVMEFWDEYPVLLTADLQGAIYFFAVMPTKTANTGKLLHAFVNDHSVPPPATTAVDSNSSTIKEETGEDVAKEEVTGNSSTFLTEAAETMMRKLLRRRKTRKSSKTDGGENPEIKAQESHGKPLGGVVACMKVALDEENPEQPRWLLFVGDDQGMIRIWDLNAMMRRLSLFKIPESKSKYLRRGYHPRATFSRDYSKETALKGTLSTASGKAGTEDSDWRHSLLYSDTRNKRDFVPSQSAMKKLSKQRIEAKKTSIAPNALTKFLPPNKVTSATAPPAAGAVAAAEAFLVAPQQRKSTSRSSSTFLHPSNNGGGLVLTRDRMHQLERRRSQCWQNQDVTIVHAWAAHRDGITSMEVSKNPNIIVTCGLDMRVFVWNWQGMCLGRLFDAENVGLARWRFQKDDSKRQAERHTLVTELMQTLDLNPHERAQRRRATVYQNHVQRRTLNEIPHVSLMLLDHIVSRDPEIAALERSGLLKQQDETSNGGTEPTGEDQQINAELEKQRKRNYQTKLMMLQSLHRTPQSAASKTDLQAREKRSRRMKSLAQVGPLLVTDRFERKTELTAAPMIPFQEEKEAQRQRQYLEDELTLQHSKNGRLKAGNMQAIKQQIRDSQAHAEEMFQNKVALQRHAAAMYGNLHELKSRSKFTLNNDEDEASQSIEKMLEPSPFLQSRLPASALSTRPQTAPNHQTSRSPATLTRAKSSGKLTKARACAIAQQRPLTASVSASSFSTRREGVSSPASDSRRGSLDMVYLSPLSQQKNEEQDDESVPTNELTTPSASPSVRKLESINNIINKAQEYCEQSAVKEASSAPGSTEKTVDKKPRMASVLEHHDESDEFESREEVDEDTLRAHLERTKHRMQLALNDGLGSFVSHATQKKQHVEQSKKDNRMEEYLQQKRREMNTNIGSVFKRTSFAFQSRPGDENALESTSKKKPPLAAGQPKALTMAMNAQARVEKNKVFGIYGVKEVMSVIRLFWSMDEDVSGHLSLPELLAYSSFFEKLGYHDMTTVFQAIDKDGNGNISLRELLEICFHYANKSQIDEMLTLAKMGNVGTYLHASQRASTVGGGASADLPVELLPEARAELVEIFRVFDKNGDGGVSMDEIMEALRVDDDEATARVMTKEQADPRSSRPSSASAVSSGLTKDDVRKLYQEFDRDGNQTLDFNEFVGLMQSLYGPRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE53</accession>
    <name>A0A8K1FE53_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007201</name>
        <name evidence="8" type="ORF">Poli38472_007221</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE53"/>
    <dbReference type="OrthoDB" id="422673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41873" checksum="BE8E787B602E9F5C" modified="2022-08-03" version="1">MADDDVQALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPKHLGIMVGMDQKDAYVGDEAQSKRGVLTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANRERMTQIMFETFNVPAMYVNIQAVLSLYASGRTTGCVLDSGDGVSHTVPIYEGYALPHAIVRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLTYVALDYDQEMKTAAESSGLEKSYELPDGNVIVIGNERFRTPEVLFQPSMIGKEASGIHDCTFQTIMKCDVDIRKDLYCNIVLSGGTTMYPGIGERMTKELTALAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWISKAEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX5</accession>
    <name>A0A8K1FEX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003017</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX5"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF11">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="10">
        <location>
            <begin position="290"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="390"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="714"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="592"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="714"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="743" mass="80574" checksum="816033E0FBF992C5" modified="2022-08-03" version="1">MTAPRSLTESASEASSKAIDVPIDGQDHPEATNEDEVEVVPLRVEPVLQQNAPPADTERGQRLIQSCRDGDLLSVQRQVVDGAPAGFVTKTGWTPIAAAAYCGKIEIVRYLLELGADGMYIKTNKRYAKHLSSGNASMSPLSSARTPSSATESLSDAHLTSNASDHSLNGHDNNGSNSTNSLTSASASAQTQVLQALKKALPEGMNTPLHWACYKGHAEVVLVLLHAGYGIEDTDPVGNRCLHLACSGGFQEVVEILLAHSAAVDPRNRYGNRPLDLATEPSCRKLLLKFQSHTTCEWCKEAFSRLRRPSLCQHCHNVYCDVKPCSSITEIVTQQMDSMRPITASSGTVRSLRYCQECASEMGKTEQDLRTHLDAKLELIQSALAILSSNQPSRPVTSRVSRPSSTQSPSRPVTANGTPPSTLPASNETLGGETTPSTSEPGTPALEMEVVEPSATEEGELPPPPRQRRRLTSDEISRALTLSQTDAEALYTSIEAAQAKNVDRELIQRAKRTYHQLVAHVALQQEIKTLMVVRPIGVRSLIEPLKTALANARREGVSDEMLELAVDVIQSAEAECTLFGCHALCAKIELGSKKFRRDIARLEASIDEAQSLNANEKLLGVATQLRDRLNAEVQLQACLQPFTPLTTVSDAGAETVHGYVFEDGAEVPTLLQALELRNQRIQSAVDFGSAVEDVSPALLEDGANQLKQLKKEIKDETKAEEERRRLEEEAAAKAAKKGKKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEY3</accession>
    <name>A0A8K1FEY3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEY3"/>
    <dbReference type="OrthoDB" id="71603at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="41033" checksum="26EE7353711CB622" modified="2022-08-03" version="1">MNSVRREGAWTQRQSGTSRAALTMASGAAKRTAIDEDKAERRRKQCRISQRRYRDKKGSTEYNLRLDINNLRENVEQLRRVRALLQSKIQNDQRLQNSSVVKAVEQYYLMFATGLHDPQSGGAHVERYYRIQVSFLRAFMAPNIKLGDGVGIVHVLKHWRRFTRYHASLSTKLNAVDVFGSATAPIVKAQSVLRVRISRTTIEKIFPHILSHDDIVQMLIGKEVAYAVCSEFVFDEKVQVVHHDTTIDFLAGLSQLLNDPYITADILRKALISKSNLLETPSTDEEDFDWMEDGDDDDDVELAGSARTIQRATDEEGKYGVESDDLEEKTDATLSGEDAASVSSATTDPDADSSSRHHLQFILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF17</accession>
    <name>A0A8K1FF17_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF17"/>
    <dbReference type="OrthoDB" id="168419at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="899"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="769"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="848"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="989" mass="106993" checksum="223A6165BD7AA370" modified="2022-08-03" version="1">MSSFFQQYPANAGASQASSAHEAFARGSFPPAPRSSGGGSDWASQRLQSTNVPSPRSHSSYFNNPAPGSDSSSSKPHLDDIPLSSTTPGAKYDTVDLFDDGKSTKRTATEAAFAQAPTAVSAESPATSNATEDQSYDQQYYQQGQDQYQQYQQGYEGYDYYYQQGYDQQQYGQEGYDQQQYAQEGYDQQQYEQYQYQYDYHSEYYHNGEQAAYGNGYEEQPAQTTESADAVFQNGAETSTPDPFSQSHGQQEAVDPFAQSQGHQEAADPFAQSPGQEAATDPFAQSHGEQVTAADPFAQSQGHHEVADPFAQSHGEQAAVDPFAQSHGHEPAADPFAQSHGQEAATDLFAQSHGQQVAADPFAHSAPSQDSNVSPFSQSPNDPFASSAPTPAPNDGPFSGSSSQHQPQAQDLFAAPASGSSASFFDRPSNAGSHQSAGDLFSQHSSSSGAFDRPHENGLHKPASAHNLFAAPSSGSSSTFFGQASQTGSEPATPANDPFAQQSSVPSQFDRAGESNHTVQDQTPVQEPFGHQVPAPSHFDQGDGNAVQSHVHDSFAHPSSAPSPFGHTNESAQDPFEHANGSTAFLQAQGPFASQSSGPSPFDRVSETSAQEHSQSQEHLIQEESTPTPFAHQPTQSQELFASHTSPASPFDHPSGSVVEEHSQSPGLFAHDASTPSPFGYPSDNGVPEESHSQGLFSHESSAPISFEQSNQGNAQEYAQSQDYYAQSTSDSAFASVPFGQEAEQTPQNGEYYAQEPFAQASTAGPFEQYGYNDQSQYYDQYSQQVAADSHETSYEQYYQGHQEQAEGPFAQTPVTQEATGHYYRESSVPVTQSQETPTPVQVQDFFTSSSQSSATQESQPGVDALFSAPPAPVAVTEPASDWKEQRNSFASATTSADLFPVNPAPVPRAPLSTRSLDERRPRRKSSTLDDSVRLAEMYKQMAERLQTEKSDLLKVLAEQAFQFQKMQEHISSMEKELTGYRLKETRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF35</accession>
    <name>A0A8K1FF35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1284" mass="144829" checksum="5A85D873C037F305" modified="2022-08-03" version="1">MKRKSRDAGALNGRRKGMMATQHVQEASAVVSVLGDASLLRLVTSYQRGIPVVFPALAKKHGITPENIEKARREARTHGKLLEPGQTFIFNVDPTRSQYLEQLKRMQASYMEMAIKDDDFRVLKMVYKLHKRGISNEHPRFGFRRPMRVAATDILLANSQILKDTSMSKRERVVAKARDEGLHTKKKVSQTEQTKAEVDVLLNPALLRYVGSFQSGIPVLFPELAKKHGITPANVTKARQEAMRHGGLAQYATPYDICKLPCQEKALEELRRMQVSYMEMAIKDNDLRVLKLVYALHKQGISSEHPRFGFRRPMRVAATYGRLEMLQWLKELEEGAEWLKDKWLLDAALKSYKLEIVQWVYGVYDGKKPSVVRWKALNEIASKGALELLQWALATFEDTQLTTDAMDGAAANGHLMTLEYLHWERSEGCTTLAMDKAAGNGHLAVVEFLHTQRMEGCTVSAMNDAAVNGHLHVVKYLHEHCSEGCTTKAMNGAAANGHFDVVRFLHTSRMEGCTADAMYGAIRNGHMDIVEFLHEQQCFFGDVRIALYNAMRKNHLDVIRFVCQHYGQDICADSLRYATSENMIELICVFEVFEIEGWTYHAMDRAAEMGCLEAVQYLHSNRTEGCTTRAMDTAACGGHLDVVRFLHENRSEGCTKRAMDGAAEKGLLDVLEYLHENRSEGCTSRAVRNAVMNGHIEVVKFLLDCCDVSCPSDVIECAARLVNWDMLELLLELDLPDDLSSVMRHVAASGHLGILKRLSHLTGIFPSSCICKAAAEYGHWYVVKYLLRSCRPNDRDADLYSTLLDAASLYGDLDMASLIVTVEDCYFPSSAHGFVNTIALGNIDLLELLWDARQGEDDWDEDFEDFEYIGLDRCAVLFATAATHGHVEIVELLRRRYPSVKNDPAVLPFCAESGDIDMVRMLLPDEDSDEAIQEAVQRVTAAGHLGALKYLVEHLLLKHGPRGMQKLPDDLLFDAACSHFYDMLTYVYEHSQPDVNILSAINVAAEHGNLDMVRYLLAQKPNVSLVKALNKAARCDALDCLRFLHAQSQQRFTKKTTHDVAKDGLLDIVKFLHEECEVDWSPSVMDVAASEDHLHIVKFLHTRRTEGCTSSAMDFAAGSGSLRVVKFLHENRHEGCSVKAMDYAARNGFLSIVKYLHENRSEGCTKAALDSAIRNQDLTMVKFLHEHRCEGFHQAVLEKALTKDPDDVGLVQHYLLPETLRDKKARETFVKRLKFDRLFKRGRFAPDVRAQEADDYDSGNESDAWVRRCRCRLGLSSNRMLHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFD1</accession>
    <name>A0A8K1FFD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000463</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFD1"/>
    <dbReference type="OrthoDB" id="310030at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035489171" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="19"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="51520" checksum="C8A088FC639B5A44" modified="2022-08-03" version="1">MMRSAVLSVLALAACAQGAVINTSVKRVVDLTKHVVRIQSDIQFVDAEDATNEYSFALSKSMGERLAHVTAKCGKNACEVVKSAESAESSLVDLYTVVLQNSVPKGETGHIKLNAHFTRVLKPFPEEITQKEDQLVVFEDGHLFASPYLTETQTTKVKLPSGRIESYSNIQPVTQKGATITYGPYENVEPFVAPSNSLRVHYKNHSPFLTVTNLVKEIEVSMWGRVSVEEVYDLEHTGAKLKGGFSRLDYQMHGARGASFYELRAYLPRDAVNVYYRDQIGNVSTSRLRQTETRQELQFKPRFPIFGGWKTQWYFGHSVPTHSVLSRSGSKFKLEVDFSTSIEEAAVDDLTVKVILPEGSTNVQVNLPFEVDAQTETSRQTYLDTPLFGRPVLVIHKKNVIAQHNVPFEVTFDFAQSFMLHEPLLLVGGFLAFFVVCMVLFRLDVSLVKKAPKAKKTKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGC6</accession>
    <name>A0A8K1FGC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000131">
        <property type="protein sequence ID" value="TMW57658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGC6"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="33161" checksum="BE6C34C526001F9C" modified="2022-08-03" version="1">MVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVAKKLREEIATMIPELVEGKIKVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVILAYALARATHVWGPDATEYKPERWVDETTGKVRNESAFKFFSFNAGPRICLGMNLAMLELKLVLTSLLTRYQLDLVPGQTITYDNALTLAVKGELFANVNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGS3</accession>
    <name>A0A8K1FGS3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGS3"/>
    <dbReference type="OrthoDB" id="165498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="213" mass="23413" checksum="1FAB033AEF3EC197" modified="2022-08-03" version="1">MSVSVAAESTKTTESAASESTTPTPTERATDMLVDEFHGKRVRKSFGTRAFWGTILGGYLVGRAMFYKVGFDDGDVDVFAADEVLYDMKEAELFKKEDASAPEPTSPNSVDQSEQQSYRELIRHKKNLKRRREESIDDDAPRGDWEVTLWGTRLYASIVDLDGLIYINELARTANGGKGEMESTGKVKVGDIIVAVQGRSAIQASGRSIISSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHU7</accession>
    <name>A0A8K1FHU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHU7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45977" checksum="E61E95F7AAC0418B" modified="2022-08-03" version="1">MTRHLPPFGTLKLTREEEFAARQQASEVIQRTLALEIEYRRQGTAVDTKEWKKVSTVDDFHVYKQRRAVRRRSDPPIRRDTTCSVDIATPELFSVRDDSSTKWRDSTIAGSESTLDRSPSSWSASSGNEPRVPRILCTGNVEGNLEDFMYGVYDGDDDAWRLRAAYIKDKFDEARILATIEGPSKDDPFRFLGIKWFTTAYPPVVGSFIQKRDTLVIESMGIAKDEHGVPYGYYIMDDYAHSNLPDRSEYGLLRNKFSMCFIHRQLAPNRIGEYARGFVDSGGNVPPAVTISIASISLSSVTNGVETAYNKKLALLMASERGRRRAASAAPSSVCESCHKSAHGVLSRSLVDCHVCGHLFCGKCIVERKLIVDTQSCQMSSRALPFCFACILRAKQLSSADLMLTPDSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIV1</accession>
    <name>A0A8K1FIV1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIV1"/>
    <dbReference type="OrthoDB" id="166952at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="567" mass="59839" checksum="AF420D2EEBF41E3A" modified="2022-08-03" version="1">MDAAMDAAMDALDVVNDAMGKIVMAKRMAHTLAAAAASVESDLEAAAPKTALETTLTVATSAANLVLLPTIVAGKAAYSATAFAVTAPIKVTKHVADSISGSWRERSTSNESSDTVDLFDDVALQPVTLHRSEDEIKIESYQVLSTKGSPVKDDAVPEVVDGVLFTRQEALGSGEDDAMTNETEEEEKKEEKEENTPGMISQLLFLPVRLVSTGVSTAVALPKSALEYSGKQLSNAVSSSQSMASSALVSSTKLVTRTSFHVAHGALTTANTVTGTVTGLVGASVRTVNYVIPPAVSSALWQGLTRTGSASTSVISYAIAVPAYRMVQALVPQIGGVVTEEQCVDVTKSGVKFLIKVLGPHKAFHFLQFTYETINSEEVHDTFLLCQDILRESLDAENYKAAGDSVGQATAGLKAVKPIVKTLGRMIPSMSELVDIASLVGEVAAVAVGPLATFMEEEETEPEPSDDDDDDRFVLVEEDEAAEHVEVSASNGEVVFDDCVFSGAADTTDDTADESEPEAEGFNLEDNLAELPALWDAGLSFLGTVCDSEEATSLFNTFGDFVDVLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJY9</accession>
    <name>A0A8K1FJY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008088</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJY9"/>
    <dbReference type="OrthoDB" id="158915at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="563"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="68174" checksum="AE4302AE01888F04" modified="2022-08-03" version="1">MLSPSPPHRSSRRVPDIVLLEESSLYPQSRQEHNDVHVLLPESEYPALQQQQTTRNGRPSLTVSQYSTSTGYQIMYRTPIAGTSKRNNSADTLPPHYGAFRPGGPVPLFTKLYSGLLLNWVIVGFFNGAIPALVYPLFYTFLHYESYQATAVTSLMDFGWYFKFLFGFISDAYSINRKRRKPYMYIGWTVFMGFMIAMACMHQVEPYMKDDEVFNADAPSQGPRYVVPFMISSFAHLLVTVACEGMMIEFAHREGEFERGRTPCIVIMSRFVGETSGSLFVSMMCNSAEYGGTFSFSMPLQWMFALFAVIAFIGILVTRFFLQEELLPAGRQRFATQLRLIWRFIEQRATSEVMISAFFISAALMLSVYEVAAISETWLHATTLTLNLSSIFQNFGYIIAAFATKRWFLNTNWRVTTLVSLTIASLIALPIELLTVFDVVRDSTLWLIKDQLAGIFEAFVWLIRLLIIIEIAEPGYEATTYGLLTTVCNLANAVVRSTYNVIMSSADPQSEVKADTNEVRWHIATEILVKLIGRLFIVLVVIRMLPRQKRHVREIKILGPPNLVLPIVVFTVICLLFVAAVTSSLLAIFKSTSCLKFAGGPGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK58</accession>
    <name>A0A8K1FK58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK58"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="93" mass="10463" checksum="33333774B87A4356" modified="2022-08-03" version="1">MTMASSSSALEALLRHIIEYGLPERDEANAYLKNERDRLVDALRKKSAVAKFWFKAFGDVIAERLASDVVLQVKQATQQIVLAMRRSVILGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLR1</accession>
    <name>A0A8K1FLR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLR1"/>
    <dbReference type="OrthoDB" id="348005at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052004">
        <property type="entry name" value="Dynein_assembly_factor_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46492">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 4, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46492:SF1">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="27"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="629"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="674"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="694" mass="77124" checksum="89979137BE68A638" modified="2022-08-03" version="1">MGEIRVTNDSLRHCTVESAANEPEAMPLTPRYTWEEDATSLALHIKLPGTALKHVDLYVSDVLVKVNAPPYVLLLDLFAAVDETSAVVKRIAATHVLHITLRKTDPKLWKQLMLEDTKTALQTRRLESMERKRVAEQALAEKRKDRKHQEEKQTLRAQMAVDDTNRQILADLKTEEKEREERAMYESFKDLQMKQHHVSVGSPTARQGSKADDNQVTHQVDAAPEPKSILKQDEKLKNKRKKRVSFAKDSPPSNQDVVDEILELTADGSFDIAAAPKSIPLNHDTQVESDTSSDEEPQEDKPSPVPTKAGTIPDAKEESYVIVELPAPRDSTTAEITFTPRVFPTPSRESKAAEEEDWLLKNRKHLKKHKGLRGAADAYDISESDPMWLKAKGDDFFRSKDYRSAANAYSEAMTAAGDDQHELLTACLSNRAACNLQLADFERCLQDCSKALTYLPDTAQPPPNHSEGQATPLIKQHRLKLKLLVRRGTALCRLGKFTEAKADYGVALTMDNQNSALQQDYYQLLQLEQADQAKARGDEAFKQNQLDDAISEYNQSLKLHSQSVACLSNRAACFLRCHELQKCVDDCTMALELLQQAPGAPTDTNTSAGLAFFAVGPAAGSAKRRAWVVKTMVRRGTAYAAMHLYDKAEVDYATAVKLDPSNTALQSDLDKIRGQHQGGKVDSGSQEAFVASVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMK2</accession>
    <name>A0A8K1FMK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMK2"/>
    <dbReference type="OrthoDB" id="276515at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF36">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452230" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="302" mass="33510" checksum="2E321DFC99756058" modified="2022-08-03" version="1">MLSNLLLAAASIALLALQSEALPSYPNAGAPLKVMSFNLRTTLANDPCPSGCWAQRKSRVQRLLSRYQPDFIGTQEGAPDQIAFFTNELKYLSFGECAGDCQWNERNSIFYDSTRWQILEGYTFALSDTPEVIPSNTWNLEYLRAAVLARFEDRQLKHTVCMLNTHYDITRGQEQSSLLVAKRLAAFCRPSDTVLVTGDLNTPPATPPIQYLLNQASLSSQRTPIPLYETLTTAGAGGSTWIGGSFSNQTTGNKLDYIFTRRDVHTCLRDARILLDTFDGFTCSDHAVIMAEFALGTQSHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMS6</accession>
    <name>A0A8K1FMS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="134"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="375"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="951"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1263"/>
            <end position="1295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1810" mass="201841" checksum="0178A6F8F60BC95A" modified="2022-08-03" version="1">MFDIEAPIELLLKTCKYKSHDRSSVLALVKLLFIQSKSPPVLDNVKTSRPMLYHQAASIASTDMSLAIDVCKLLNMLKYEINMIDTRTGETALLQECKRLCESEANINSDSSQLELVRTLIQLGASIDFPNEVNGETPLGCAAAYGNLRLLDLLLEAGAQPNVYHKLSFSALHFAVRGGHFACAKALLNAKANISVQLPPRQDETPLFFAIRSKNEELVELLLQNDADPCALCTIHHSLTTSFNIRLSIWSEVKPQITRNEPKKREDAPVNNNLIKAASPLTFALLLAQQWTPFASQEEAIGIDRARERHDWEVFRSMTMILARHTLATTAPSGNTASSLITRQDIDLACRLGFWDLVKILLTYQVTLSSARTVDRMNALHLAAAAGHTDIVTGLVAAGMNVNSVLTRKTLGTNSSRVPTIRTNFHGQQMMNAASIGALHFALVNGHPETAAHLLVLGARPLETMIYYRSARRVRDRANDIWVDREEVIFVVSERMDKKMRDLYFRGKGSQSHDTPVTQSYHRERVAINFVQHLQMSINLRVPILHYMAAMGYTSGVQMLVEAGMNVLQSSRLTNPFNLKIPEWNAESAIHVAILRGHLDVIRYFAMLAQFNFPRYFLRENQKPESLLVVACRTKRADVVRYLLSNGSVNGEGGGYNGRDSPGDIEKAMNTCAAYHFEAGFDMMLTENGCPDLVTLVQVVQSVHWIEKEGAPFVSSVDSETTAMPSLDLKKPIALPLSKRVHLRFCASSHRILLAICRFSQNFDDFFKVLSFDHILKLLIICSQYEQWEVLEKVFVANESRFLNALNPWTPILVRAASCCLVMHRAAAANQVGLIRFFLKLGVPADLQLNELGAVKCPVWYAASRGALDAFVVLALSSTNLTQALTSYCVGGFRVHYRSVSATTSWFSTASTCRWQNLSSMSCYEISKSQRAVYLIQKLINMWIRENRGRLGNSLLHLACETGNLSLIQVLVDAGADILARNTAGSTPLMVAAARQDPFGASVTRYLVGQLRHRGSDEDIASNLGRALVSCFAEPPPCNLKTAKILLAAGADPNYQDGERSALMHALQTLQFAGTKVLVDNGGKLTIALGETFLQRVQSIANDQATRWRRYSSLLKQQGQNLLEVESLLLLFLDKKNGYTVNNDLLLTMLTTSAAIAATVAKASGYDQKFWYIVSNILDQYGSNVAARKSEWNRKSALHFAVQAVEIPIIRKMVDVGKLEVDAEDENKVTPLHLVAYNGDPAACQILLSGLRDQQRVDSVDSKGRTPLHAAITHGHEAVAMQFVAAGASLKIYCHQGWNALVCAARLNHLSILMALYARDSSRELLYSRDGEFAMFIAANHAAFRVVRWFMAMYKDIQSPEASQAIYSVTCKRRLRTLLHYAAIYGDQELINTLLTSEQCPSDIIDQRDAAGYTALMYAFAFGKLAVVETLCRFGARADLLIDHTGDVNAHPYASSFTVGGLSNWFALPGWFAHVSSQFPPTEKRRLTSFVTSEEHYLLGSGYQKRKVRAPIHTDRFRTDLLREYETKKVRTTMKCWQFPRMSLFEYAQDVGDESLISLLIRLGLSSLVQTVSFARRRNGFLQLVRWNRLEIVKVLLESASKSVWAEFVEVGVDCAVSRGLEEMTIYLLSKWQGHKDSSVPADASAFAFQFAHVFQVACIRRLLRLIEYMIERGGEHIVVFHWNEGPALVYAFAFGHADIASRFIAQGAHTSTMDTYRAPSFKKWIEYGCPQEVQVSWYELSAPKEAALREHIATACPPFIGPVEVYEPPHERLDTKAMASLFLPADNGEEEDTRTTPELSTDEVYVTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMX9</accession>
    <name>A0A8K1FMX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMX9"/>
    <dbReference type="OrthoDB" id="1650at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000038">
        <property type="entry name" value="Exosome complex component RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="88"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="297" mass="33393" checksum="F44BE6D593732278" modified="2022-08-03" version="1">MRIEVRTKAATDASERYDDVDMDVELPDEGSIVVVTPGEVISTETGAFLRGHGTYMSNNELIASVAGVVEKVNQLITVRPLVSRYIGEVGDIVVGRITEVGKKRWKVDVNGQQDASLMLSSVNLPGGAQRRRTYEDQLQMRNFFVENDLISAEIQEVRYDGSLSLHTRSLRYGKLENGQFVQVQPSLVKRMKQHMVTLSSIGVDLILGTNGYIWITRSMSALGLDDQMEDTGPGNMETRVEVLMEKRQVHANTKLDVDDRVKVARVYRAILQLNEQFRMITPESILSLYADFADHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP16</accession>
    <name>A0A8K1FP16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP16"/>
    <dbReference type="OrthoDB" id="38351at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050663">
        <property type="entry name" value="Ankyrin-SOCS_Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193:SF121">
        <property type="entry name" value="ADA2A-CONTAINING COMPLEX COMPONENT 3, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="295"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47593" checksum="F4F710F794C2E3E0" modified="2022-08-03" version="1">MEVRLSGLVTIAPYFTDVATSETLTMHQSELFAAAAHDDVDAIERFLRQPALEASLSVTNDRFRAVYKAALARNESPFASRRMEAVDAWFTMPNPEAPGYNEFLLDGPIRRGDMHTVAWFFGSSATELIGDTIRGLLERIYRVMVIIRGLSPEFTEMVLSSPLYCSMDSKEQAFALSMMLDVASGLGRSAAIRLLVAHGADLTTLPSMFGERGNVQATETLLDCGVFAVLHQVLTDTARSRRCDLAEVLIENGMDAQSVGRTSGPLHVAAEQGENELVELLVTRGFADVNAHGDGGLTPLMSTLAQGEVELGVYGECPPLIVAFLLENGALVDLRDDLGRAALHHAVRCDYTVVIRLLLNFGADVNAQDAQGLTALHTVAQMVYHEDFERLDVLFSHGANPFVQDQDGRTALHRLRETEAGREYITRHFQYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPI1</accession>
    <name>A0A8K1FPI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Developmentally regulated GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPI1"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="65"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="290"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="41488" checksum="72AAF918C0020FD1" modified="2022-08-03" version="1">MSTMEKIKELEAEYARTQKNKATMKHLCLLKAKIAKLRREITDGGSKSGGGAGGEGFDVNKVGDTRVGLVGFPSVGKSTLLTKLTGTFSEAASYEFTTLTAIPGTLHYRGARIQILDLPGIIEGAKDGKGRGRQVIGTARTCNVILIVLDAMKPATHKKLIEYELEGFGIRLNKSPPNVVLKRKERGGVNYQSTVPQSELDSESVHQLLHEYRIHNADVTLREDITVDQLIDVIEGNRVYIPCLYVLNKIDQLTIEELRIIDQIPHNVLISAHHMWNFDELLEGIWDYCKMMRIYTKPRGKQPDYDAPVILHAEKPTIEDFCLRIHKSLLRQFKYAWVWGSSVKHQPQKVGKEHILNDEDIVQIVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTL4</accession>
    <name>A0A8K1FTL4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001859</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTL4"/>
    <dbReference type="OrthoDB" id="162167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="373" mass="42197" checksum="3C38E585D683D7DB" modified="2022-08-03" version="1">MSSTVVVETPPKPLEAVEVNGSDVVSPSAPVAVEDAKTTEEEVEMEDSKTASESEDGEVEPMDLETEKTDGETNGEAASASAPSYTVRRAEDDARALELAKRRLQIQIAFVENARKKLEEESHPDFVARLGKLEEDRDRLLDRAKIQEAYWQHCTSVIFDYECEEASSEYLLNCDKLRQDMLDEIQNEIEILNDQRKGSSSARKTTRKTRSTRTKPGSEEKTASLESAHRIKKRVGNVFQQLENRLAQSEVDHDLRELGNLLDSANKKRRMDVIYPNDLPYVAKYHRSTFLYRDEVFQEGDEILVRNFMTGVDYAAVLCAITSTELFVLSEKGKYSRLVLMDLRQGRVVVSALTPDQIAALNEREEREALLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2L7</accession>
    <name>A0A8K1C2L7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TAZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2L7"/>
    <dbReference type="OrthoDB" id="168290at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="25356" checksum="34F7A11CF8018281" modified="2022-08-03" version="1">MTSSRNEIVYPDSLRARLHALMPPFSAPPPPSAVSVASAAAAAATSASAPPSRKRTIDAMSPLVSPLLSYTASTSSTTGLDAFRIGPNSVNVTNGSAHAHASESLRSRPAPSATYPARAPTSTSASASTEKIRSVVRGLEHVARCDPVTGCGNPLCVSTRTFMQKVKTHLVAMSSKPNHVAAKCGACQLWLSIVKAHSNICMEANCSIPLCATTHSEQTSAESSTKRRRGEMEQLAFRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2N2</accession>
    <name>A0A8K1C2N2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2N2"/>
    <dbReference type="OrthoDB" id="118154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42425" checksum="0F2B3E148191240A" modified="2022-08-03" version="1">MALDQALHFLDELKDKYMHEVEKAIEDWDYQDFSPDKRTPLLENEISIDIADDLAPDANAIQQIKDAHNIDWSGLSRDEALADQDYGMMVGSNASLSFEDRVVIMATPSSGVQGLPDCDTLQRFLFHAPQLNMNLVAEAFSTRLQEKAWQIRSKTLVLIEVLLEASELLPHCLGAFLAHPSLMKVLDAVRREDRNVMSRERARKVMSLIRSNGANAMLIARERMSPKAHVRHTPTEKKPKVKTPVSSPVAKKQAGNKTQPKLKVNTMAPVKESQHSYQTTSPTVAAAALASWRRRSMKEGLGGLPNLRKDPPNLMPFQKPPTMTATMSLTQKMNQASAAELAPAAKKRPSLSRFGSGNLSAFAFMEPAGTSAVKRSSRTATFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2R7</accession>
    <name>A0A8K1C2R7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2R7"/>
    <dbReference type="OrthoDB" id="167694at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="302" mass="34574" checksum="8A528388E010E1C4" modified="2022-08-03" version="1">MRVEYEPPLIHKPAKYAMPTPRDFPRRASTSTTTTLPPPRVTTLASRDQLTTVSPPSATTNIVDDFVVRKRMRTPHRNRRVRFQNANAPDEIPRPRVYVDSYDDLFFRVARLDHTLSAHDSANGDFNSESSASSMDTVNSDGEYIERSEALLIAEFLYRSAVYLGYPRDQNAWMPNFRDNKRFSTNDAKRWRRLAHYDWEQEDEVFEAVSPFDMSMVPPEPGSKSLRKTVSKWIHRHRSRSTKASSPPSSTVPTLSNMENPPSVPEGQDLSRLVVIANSCISYGAFRFREKDIRKLCNAACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2T5</accession>
    <name>A0A8K1C2T5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2T5"/>
    <dbReference type="OrthoDB" id="129126at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="272" mass="29992" checksum="05052FD220C33A2E" modified="2022-08-03" version="1">MAVLLLAGAAALALALLTTLTILAIRLVLWFSLSYTLATALMGLGYWFVVSRRKGVAKGFYSCQSAPETPVTTPATTTTMQQGVKYVKPRARVETKENRPHVQETTTEKNEDVITETTPAVVDPEDIEKELTRRGDPLSATESEEDARGTGDDSGSNDEEVPVYALPPETPEQMDSPLPSLQRKRRLTPSQSVPMMKVKNANEASAPITRSVAPTSSHRHSQSQRVLQREQRQVKKAMEADGYWIGDFRVPPPVRSRPRPPTIPQPLSEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2V8</accession>
    <name>A0A8K1C2V8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2V8"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="494" mass="55775" checksum="E486BD55A7DDB396" modified="2022-08-03" version="1">MNKSAAETMVALAERAHEVELAARERSHTGIVSPPAEVEGRVFYRLHQYTLLPPEVQTQADAVAVHLATPDVRKRVFTSPKWRHRVAKGPCVKGQKLVDAIFNFLARSRAEVPHPAEAELLAGALVLSGFVSPTNEPSDEHDIGKYILANEFYELVSPGALKIMHRSAWTSPERPPMGQKLSVWAVTDGTTRAGFVYRKSEPSSARMLLSMLSMCSAQGHEVKSYVVINKIKHHALFVFRDDTAREELSHLVLDDALVEYDNGSRTSPMYHGLKIWNDDHAEWFDFLTREQRDKWLLSILDGGAKYKEAHPRYDELAGSNMSLYDLIDVDAVGEEIHLGIFRDKVILLVNVASRDPEAALQYPELVELHEKYRADGLVILACPCDQFAALEYEADAAILQHLAAMYLVDFPVFAKRDVNGLDARDLFVFANAHLPGMFGPFVEWNFTKFLFDRRGRPVKRYETSVLPHRMENDIKALLDTQKESQTLHESVEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2V9</accession>
    <name>A0A8K1C2V9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2V9"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431678" description="Glucanase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="51796" checksum="D7AD8E62E361A53A" modified="2022-08-03" version="1">MWRTRSLMMAAAVALVASLKGVVAEELCSVAPGTYAQAKINYPEAAFAIAELEKHGIATWYTDREGAGDYVATAKQIVAQCPSSSRLSIVVYGLPDKDCEAGESRIGTRNKNSGMYQEFVSQLQQAVGDRKVLYVVEPDAVGLLASGGCATQLGYKENVATAISTLSKNPNADIYLDVGHWMLSSPSDLSNVASIVRSLMTAGRIKGISINTSNYRSNSELSSLCGNFRNAMSGTDLKCIIDTSRNYNGPSSQNEWCNYKGAGIGKVPTSDTGDANIAYYVWIKPPGESDGSCAGRSSDAMVSTSAGGFFLDYFKAVWNAGSLVKDLGMPKIDGTIRDVPSTTTPASSATPSPSNSSNSSSPAPSASPENGVVGSSTGSKAVGSTGSSFMDMSTKSVGVVTAPIDDPIFKNSVAPITSSGSSDGKINEVTTKSSESTSMGSGVIVLLVMIAVAAVALTVVVVIRKRQRSLEETKSPLEPRIHYLSNSPRDISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C305</accession>
    <name>A0A8K1C305_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010407</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C305"/>
    <dbReference type="OrthoDB" id="75360at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="11083" checksum="21647E5FA54B9102" modified="2022-08-03" version="1">MLSTIAKRATRVAQPQGARNIYIQVRSNQDPERVTSRVHGIMNEDGVLKSLALKRFHEKGARRRKRKMEEQTIRHVNRRIGSMIDFILKRKKAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3D9</accession>
    <name>A0A8K1C3D9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tryptophan synthase</fullName>
            <ecNumber evidence="3">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3D9"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000001">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000004">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="74"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="45802" checksum="2E06B676CE1E808E" modified="2022-08-03" version="1">MNTEDYTHYLKVSNAPPVYNSAEELNAYFGRYGGCFVAETLIQAHHNLIDEYVRATKDPKFREELEHLGRDYIGRPTPLYHAKRLTEHAKGAQIWLKREDLAHTGAHKINNALGQAVLAKRLGKQRIIAETGAGQHGVATATACALLGLDCVVYMGYEDTQRQSLNVFRMKMLGAKVIAVKEGSQTLKDAVNAAIRDWVTNVETTHYIIGSAIGPHPFPTIVRDFQSIIGREIKAQLEEEIGRLPDAIVACVGGGSNAIGMFHPFIKDESVDIYGVEAGGEGVETPRHSSTLLGGRPGVLHGTKTYVMQDDAGQVIPTHSVSAGLDYAGVGPEHSFLKDSGRAKYVSVNDDQALEAFQLLSRQEGIIPALESAHAIYYGIKLASQLDSSKVVVINVSGRGDKDMLQVAKELGVDLNEDLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3X4</accession>
    <name>A0A8K1C3X4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3X4"/>
    <dbReference type="OrthoDB" id="77109at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="30615" checksum="33F4E4AD4B14F2EC" modified="2022-08-03" version="1">MTSDAQPSQSYMALIQPQVDTHQVVALAVDEDKTDRHGAPKKASDERAHLLPAMARDGRTSPVSALHTNNERVYPCPYESAVLTNKTDHTASPAKTIDGDQQQQLIVRARPSVMTKLFGKTVSTPIDISPSLKESGHHASEPRSYGSIETKRRNSILRMNSARSPHDRQLKKSASVEFMLHDEEVKEVNKSRRMSGSNFGRDMPRRLTIEEKEELYRERPDLEIGPAPFFQEHLDELRRRNQRRLLYAIFGGVLCLVFLMVFYYLLTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C465</accession>
    <name>A0A8K1C465_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008844</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C465"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="617"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="158"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="733" mass="83306" checksum="65E4CE4F5C971FF2" modified="2022-08-03" version="1">MNDELSDLLSFTSLSQSPSHAPMTDPIVSESPTPPQDRNKPHKQHHKSDRYRHLEERIEELQEQMATTQEMIRNLTDIIQKQHQAANARQNLRLLTAKAVGVQASQGPLGPTTAILKPFIPSLTDNVPPPETEFLDNAPDPPPPVIESRVQFKIDSNGVKSFDTTSSDPSSQPPRKMSTGDLSPARRRSASNPITLTTNQAKKNSMAQALAHAASFVNQLAKGATFRRLFPDNNGPNITRRFSMSSLDLNGAQLNRPSWIERWSRTLFKRRVEPLVSPQEIRDARSEDTKVHPFSIRHDTVQRLIWDIFIVTIVLVDVVFTPLSLSFKYDPEGLDSFNILGSIVFFLDFLVNMFSSYTTERGVLVSGPSQTIRHYFLSPLALPDLLSWFPFEFVVSKAHGRFVSIVKIIRLAKVSQLAHRVHSSKKAGLIRMLSLFGSVFIVSHLLSCYWNWVAKEWRDNEEGYMEKPLIEKYAHCWSLVIGSLNASPPAMFTSIEEVSVAVFMLIGNVLQATVFGSFAVLISSFDENEVEYNKKLISTYERCKFLDIPDKLARRIQGYYENLYRETRSVSPDADAFINELSPALICEVKFQLYRDMIKQIPFLSATHINPVVIEMLILHLRTVIYMQDDVLIRKGEFGDWMGFIGTKGSVGVLDPQSNQRKIIRILRKGDYFGEMALLQRAKRSTTAVALSWVQIHVLCRNDLDDVKEQYPEQAEILEEEINKYMKSKVTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5A3</accession>
    <name>A0A8K1C5A3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphodiesterase</fullName>
            <ecNumber evidence="7">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006568</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5A3"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0140">cGMP</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="10">
        <location>
            <begin position="751"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="825"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="825"/>
            <end position="829"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="829"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="865"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="865"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="865"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="971"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="971"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1024"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1104" mass="122977" checksum="E354431EAC10B12F" modified="2022-08-03" version="1">MVAVPLGALQVAIEGVRVGVEKKQQLREELERAETEAKALQQKLRKRQDQLERCAAFRPEIQRPTPPRVDVGGANRGGRGDPRAAFRSKRSKSALFSSSMRDLVGELADEMNQLMAREENLRALMDATRDLSQKSDYLDVVASALRAAQSVIAAEKYTLGILNEKKDGLDLYSNPPVLLPGRPVMEEGGLVVDSNTTFGRVILTGKSLEIDEIGDSDAVDLFEDQLSMLNFEPQALLCAPIFNVHGIMVGVFQVITRKRPVSAPMAPTLEEHLDDDGQLVSSSSMPSVHSSMPFKTIFSPLEKESFRYICVITGTAIWNMALAKAHQIAQGRIECLLRLNRNISVETNSSSVLDQIIAVSYELLSAESIQLYVRDEGTDEFYIASGTGGGAKDEYHTEHNGIAGYVMRTGQLILTNSAQEHPEFDPHFDVATSFHTRQVLCAPVKDADSKVLAVVCASNKADGGEFTPEDALYLNYAADAAGISLHKSNLLREVITSQRITEARLRLTDFVGSSTPVAEFVNLVMEEGKKLMNCDRFGFLLVDQLKKELWITQIDGKNIRMPINKGISGLVAMTGERVCTRDAYTHSWFDPTLDKKTGYRTTSVLCMPVFEDHAPTNPKIVAVVMVINKKDGSRTVPFTATDHVNLERYCHEIQFALGRLSLDISYYKVVSDCEMNGVNASSPQAFSPEPKVTVTSSVIGAGSEEVTEGQIIASIVHKYCQGNDLEGLEVIASASSLPNGADAWVASEAQNEDLIMIQDSGNIVGIGDVDRWDFCSLDLSNADIFISITVIFRVFNFLDIFHIPGDKFATFLSHVASHYRPNPFHNFQHAFQVMHTTYIMIRRECSSYFSSLDIFTMLIAALCHDIDHPGNNNDFEVKSLSQMALTHNDDAVLERHHCRVTFIILGHASANILENLPRDTFLKVRRLIIHCILATDMSKHFEKCKALEGLTKRHLAEKKYVFMAILLHASDLSGQALPYDQAIRWGMRVLTEFQNQAKSEAEMNVPVDSFMTNLHQMKTRITVQMNFINYVLRPIWRPLGALCKQLRVYSDSLEANFDLYKTDLEKIDVDQEDPPAVYVRGESSRLLSRKTKEGARVSTRINEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C694</accession>
    <name>A0A8K1C694_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C694"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="523"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="993" mass="113871" checksum="9B335F82421E51FE" modified="2022-08-03" version="1">MTIIREQQPTSCNMADEEAAAAVAALSLNEGEDDHSDNASEGYDSEHPWPRLRVISREQNPRYRPTREVDSDLVFTTITTMPAYQETSQEELRWARYFQDEKALEEEQIGQLEARAMEPPRSQFGTATPQFEGAVATTRTDYLKTFQCITTMPDYLEKSQEELRYEDMLLESHTEEEAVAIARCEVEPTPEEPSTAPLSRQRTRMKPGYEQVLHPSDTGEWRFFVAITAMDAYANKSQEELRVDAYGEFRGPFSPKTRLLPRTIMEIHTRAAIDSMQEKSQSHWDRYVSDDAWRERWLDNAAHNVLRPTLVETIRGWFPVDNPLFTTFVGHETDPILLAPTSEEKSLRIDAFCSLVPFSLDWIDLNEIVGGLAAPPSSVQDEATDTQIDSLAGDKRLADALKLDAYAFVGFYCSMVAFADEMKSVAADLWNMSSIYDVLATRRERIATETAMKMIRNFQTGETIEEAVEHATNVTETRSWILRALELHIHRIVHDMEQVKHQVNQSLHHLIASTELTRDGRDLVRLWTSDAVYFSDTAVDSDATKQLQHEVDVLESCREGERVWAPTQRGPIRFLVDPLKYPFIDRETRRIPCFGEQSYLDPYTQMSAIMHRGSIHSRRYPWAFSFYWVSDELYPRPTFPPRGDFSPEGCDLPDVYEDQEWVSWVENPVSRTFSLVTLDPLVDDYVYCQRLPSEFFVDEGGHVTIESYINNLHPLACRQLYCMIERVFEQMVPAFDGVLSSLLEAFPEPWFVSEWSKPYVRSHLSPRPGFPHSPEPPRGGSHTTFTMKGHRVQVIVSMVEIQLDAETPEFYHEQWHIDARKVERVVASGLYCFGMENLTECRIALRSPVNPPFTMQQDLNSMAAIYGFTPQTDPVIYQDAGSVSIEEGRSVTWPNYLEHQLLPFNVKDKSMPGKLQLLRFMIVDPFHPILSTRDVPPQQLQWTDAGIDAIARKYHLPDAVLDLIQSMTRFGLSAVQAEEERVKVEASSVLQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6H4</accession>
    <name>A0A8K1C6H4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6H4"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="50"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49614" checksum="0E8C496B810F9289" modified="2022-08-03" version="1">MQFFTSPREDLETTALNASMRAVQVYEESAGAMTFDVNEHAEWCASRVQAPWTIHVREPESKGTYLKKHTTFLVTEDANNFSVRRRFSDFAWLHSVLKARYIGLLIPSMPEKNVLKSEAFIQSRMRGLTLFLQHIVDSPYLRDDLAVTNFFTKTEDAAWDAAKKEASTMESGGEGHVRWIKRIACRTMPAAIENEIASFKRQVEQQEKILSELLLCTKRLTEKSLAHAKDTAHLLTLFNGWTVTETTSPTTDAELLLALQSTTTVVDGWSQTVRHEPGIYELILHDSLKYLHQQARDMKDMLHSRESSINAAQHAANGPNATSSSPFGVAGAASSFASRFRSTESSSADPELAQRRSKHASEMIARALLAEEMERFQTSIRVCLGTTVQQFAFAQAEVTKKAGTIWRDFVKANVQDRKALLESTTQILENVAPSDEVSSAEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C709</accession>
    <name>A0A8K1C709_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79876at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43049">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43049:SF1">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1563"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1649"/>
            <end position="2458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2491"/>
            <end position="2761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2795"/>
            <end position="2828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="286"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="410"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="518"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="610"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1566"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1589"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1618"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1654"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1678"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1694"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1735"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1757"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1778"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1790"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1811"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1842"/>
            <end position="1854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1903"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1915"/>
            <end position="1924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1939"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1953"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1971"/>
            <end position="1980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1981"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2004"/>
            <end position="2013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2022"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2088"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2107"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2137"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2165"/>
            <end position="2177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2211"/>
            <end position="2225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2236"/>
            <end position="2262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2263"/>
            <end position="2281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2298"/>
            <end position="2307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2345"/>
            <end position="2367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2397"/>
            <end position="2406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2504"/>
            <end position="2516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2529"/>
            <end position="2540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2541"/>
            <end position="2550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2575"/>
            <end position="2585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2600"/>
            <end position="2609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2620"/>
            <end position="2636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2663"/>
            <end position="2672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2679"/>
            <end position="2698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2699"/>
            <end position="2708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2740"/>
            <end position="2761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2803"/>
            <end position="2828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2828" mass="317190" checksum="55251B1F09B3639B" modified="2022-08-03" version="1">MSGYNNEWEADLSSIIEKTNQNLKLLRRIGEKRTDLSSATYDVSTTAPRASVAVGETRQFGASISSRYAAEDMAIRSRTLWGGASASSRRLHRSSSMGVTPPHGTVIRPAVPTNAFEDTEDSGDVGVTATRSGSNKRGSTMAKARSTRVEAAPDVLHPAIDDLRKSLEVSIAAKSNDVEKKLADLRMDVSSITSESAALSQRFNELRDSVVTKMSAVPSVMQGLQDHADAVGRLEKHSAMLLGWKVSVDQDLSEISSKLKSFTAVHDKITALEGHLESLGAILKNRPRHEEKIEELRDRIALLERQLSNQPDTKAVEHLVQMRLSKEINELENRMNQSLAIVTQKYEAKFQALEKSIHTDRIDAITSVKSELLEDMDKLEAKMVKKGDLTQMASTQAQLKDDMVHVQMFFERQDKRFQELKQNSTQIREELNETRQELTKALHAQQNRVNSTLEEKVAHLSILSKERNTKMDQHVGQLDKKQKKLDEATKALHENMIKMQQEISRKQAAANVADQRENDKLRQRLARSIAELEQLHTTKQDLERQYEKQEKHFQSKLNGLRAQVEEQEKQKETQRLELLQALQQESKQMGVAHGKNMLLETLLAKEKVDHEEKNQAIHKSRQEIAAVRQKMRTLENEVDKKMTRLSQELSAKQSMIDSLQKKLKRSEDEAKRLAEAAKRDIKALRKGKELKQQELVLAKMKLKEMEKVAASLMADVDDTSTQMDHAERYEELEARREELENLLISRETEVEDMKQKMAALAMELEDTRRRSQEMTEVTVPHLSTEVMDQLAALQSDLVKKDAEMKSLRESLVEKTEVQVLESALEAVKSEKEDLLKQIKVTQESHARASTEVEATLQSLHAKEVEQLRKRIQDYVNEISEAQTALSESRERITHLEADLSRLQDNHKGEVSKLADKLTDSEGEVVRLTEEIGRLEADKRHVDDALAEYQAALEVAKSENEDQAEQLDALRQHEHDLVQERDQLEVQLKKKTDELAELMDASQRQQAMIDNTAGELEETENRLAGEVKTLQGLLEQERAAATLRERELLSMADVLRLELETLKQDAQNSGESQSSLAKEVASLLEAVQQGKDREQALSSQLADVLGEIVALTQSSSAQHVDQEPTAVIECVRSLTQEIKSKTEALHDLREKHECAAKQAVAETARVKELEERVDEYSRQVAELERTTIALRGELQQSYAGAATHAKNFEDVQEHLTLLREQKHDLESQLEENIAEYENLQSSSSQNMRERQAELAELRELNQKLESTIEEIRDSMEQLESKKMEDLDELHALLGDLENQAAHLNTKSNKDIMGTEKDFYQNQQMVITLGQSVRSIYAKLCSGCGIIELQDLRASLMNEEVKLDRLRQENIKQRIRCVEAEEEVLLNVEFLTALTQNADGNALASKYVRMAPDLLKRLQCIQDAWKAAVASLSVIAVEHTDEELDAVDRSVSDTMAGLITNLEESVDLQDHASELSMSQLDESQDFAAIAESSGDVMATRYESNYSASPEPLVQYHQANASASSDPSGMPTVPSLDLRNVQPYVESCVLLPSSPTAELLQTRLRPLHAPREPERSTDMHSTNDFDDEEDQVADHDSEQDEAAHSEDVDDDEESEHHDEVTSSPPRNQTGVNLMVSGELRNRENVVESEIATAENDALFDDEDTPDNETDNTSRHAQLTREDEEERDLEDLDESCSEIDRSAELNDHLNVDNSGDIEEADRAHDAEDEGLLRSSIRLEEDEEDGIDHEEEEEEEEEEEVRTEHADHKGDWVHLSAPRVEEGGDESDREDESEHENHELRDREQQEAVHPLVRPEEDDDFDRVDDEVEHDQVAEQFPVRRPTGSEAEAEIDRVDEEDDTIHYRHDVGIAHPPVLMGEEDEEDADEVSSDEREDENSFDGHNQGVARSFDRSEKDHDDNEVVDQDGGEDEAVHGRNGAGRPFDHEDEDEIDRDEGNDEVEHDRRVEVTMHPSSHTEEEDDEDEIDREGAEAFKYAEHGAGVSPPSIRMEEEDDDEDGIDREGGTEEGALEEDEDDLIDSSSDVDGDEESEHSLSQLLETMLRLATHEGGRPDQTPTGDTRQSRELPRTTYNGIEDDQEDDIDHEEDDGDDEDHGHKVVERMVDARIQQSLGFQIDDNKEADDAGDAQDEEDHEESIDEISQQDGESWDAEGSRGERPHHGDETVSSAVCEREEQSDDENDGGELLQSTEQDRMQSDFDDEADLNEQLDDEVAFHPPSSTTEHVERSEQPDSRWDQKDNADVADHDNLDKDEDVENSEGDEIDASDEEPSRSTTISSAHAAHMEDDEDLDEVEQLMRQHIKPSRLYDDKPAIQQTSFVHKASADAVGRDTDEADRDDDLVDSEEEEADEEEIEQSGVEDSQDFGDMSLQLDDGDSDGVRVESTHTTGTNEPQHASVPARGAESHSDDDTDEEGTAAQHLAPSPAQVAVSQLPPLSGMRRPGGVGTLMKALNATRATMNFDDDKDDMDEVERLMMSQSLQHGAKSASVPMPKHDLVDSSKNVENDDEFDDAPAVLRVEKGDHEKEGDQIDDPNEDSVAEGSAALDESVEQSMGDEFSFGETDLDRLLAEDSSKPSATLAKAGKTHDDEEDEEDDDDVKFGSGSRPWSTSATSFVSSSSFTSASMARPGSALPTLKKPGLGSLLGQRSTLAEDDDDDMDEVERLLLAQSSMKTSSSLSRQPATQVPETDDFDDGEEATSPVDTRRHQVPPSHDDDEFAHFDHDESEESSATSPHKATHNGLSESTGSVSSVTRIPIFQGSTLADKVAKSDLTPLAGQRVVQEAAKAHHQIEDEEDEAEDYMEESFDLEESLQEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C714</accession>
    <name>A0A8K1C714_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003559</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C714"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07346">
        <property type="entry name" value="ABC_6TM_exporters"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF620">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="306"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="629"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="868"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="927"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="894"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="993"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1002" mass="111113" checksum="DBDDD48B661DEA3F" modified="2022-08-03" version="1">MVNKHKDLERGPDDNGPMTGTDADFERVPNDNFHKIGGPLPETSDPRTIKGAAGGSGNGNRLFFLRVIDSRKWHYSETFALFLDFFVQLLAISFAPKKNFPNEVAAKSSRFFSSGLMVCYLIDMVIRILGLRAALLRSHSNIADLLCLLGMAGMLGVRYVMHEYEYYVTLGYLALVAMRLILKPRARTFSKKLHKFRANGDHIRISIESLRASLARIPGISALSIEMMETDLVIICGRDVGDMSRDELMQFLERALHYRPPNLSATEFLGHLRDIDASSSNLAYGVTDVVRSTLWHWSNQSADLMLCFLVVCVNAAISPALSFFTTKLSDAFDTLTNNEPDESILKLGILGMLGLCVPFVIGNYSIGYFQSKMISKATELMQSNLLNIILHQDTAFFAERSEGDLNNLFSSDVARVNGLWQAVFWNLLNPLVAVIFGFGYALYMDYSIGVMAFAFSAVLLSSGPQGFAAQRSKEFGSKNAYVASEFQNAVACQKVVRAYAIQEPLMNKFRATCSVLRKNQFSKDFWSSIVQIYIESAMYIFTAIMTASLAMKVWRKDDGISAGDFFGFTTLLQRVSSPVTVLGGFMRVAIGNASSLQRIDDIILGMGPSSTGDNGDKDLPALPKMERDLRVEKLVFKYDKASEKYILNELTTTIPRGAYTCIVGPSGCGKSTLLACLMQFQEADGGCIRLDGHDIFNFSKKSFMDQTAVVFQDGGILNGTIYDNLRYGNINATDADCEEAARLAECHFIKDLKDGFNTVVGQHATCNLSGGQAQRICLARALCRKPSLLLLDEATSALDPETEASIVATLERLSSKMNMTILSVTHRLSTAVNADLILVLNKGRVAEEGRYDDLVRRGGLFYEMVHKTEEDEDEEDDGKKQKEPAKKLSVIRKSIHEPAQDESTRSVDSVLALQQFTKTLSSRVVHDPADTRRAGNGTSWYRYGNRSSHRSRKQSGDEAFARRSQNSSMGDWYEPPANQGRRPATSAASQASEEDRSKYFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C717</accession>
    <name>A0A8K1C717_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C717"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035420333" evidence="1">
        <location>
            <begin position="21"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="225" mass="24791" checksum="AA3C78AB5CF55036" modified="2022-08-03" version="1">MKSIRALALLGLSYVGVAFAADAPATEATTTTSTPPSVEAEIVTGPVTVPAPTPVVEASTLSSSVVAAKPPSLTETVGVKQEGLDDKKKETKKYGYDDSYDSGDDYDYGYGKKKHYGYDYGYDDYDYDYGKKNKKDYGYDYGYGYGYYRPSYYNGYGGYGGYGPSYDYSNGYGYGYDNGYGYGFDNGFGYRYGSFGNGNAGYGYFNPYDYYVNANGYYYPGGQWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C856</accession>
    <name>A0A8K1C856_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Osmotin, thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C856"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013">
        <property type="entry name" value="THAUMATIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013:SF2">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035440548" description="Osmotin, thaumatin-like protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="43710" checksum="48121B7A950B354D" modified="2022-08-03" version="1">MISTKLLCLTFALLGAARAEDNSTVDRSQVHMPHAKMAQEVGSNTTIKESSAVAAVHPAEVESHPAMLAMAASREVELYNNCPYEVNYKYTPGFNTPVNAFFPIPGPGPNGYKLKAQERHTASFINTWSGNVGVCKGDSCETGAACTGGCGVANGGPMTRAEWTFVPGGTDYYDVTVINGVNIPVKLEPLDVQYNSNDPYKCGAPGKVLDVVPGSGCSWDYAKFQNDFHYNAVTGGSGKKCGAPGDCGNGEVCGYKFVPGVGLGMYCGKRYGFYSANQVCALDGGNKHFKCDESAGDATGLKIRDIHGCVGPQYLSGYQPASKGKDGEACGCTDWQDRGVKVFNTPPTEKCKAVNPKWIEKIVPTLDFLKKACPTTYTYPYDDMTSTFVCGGEKKYRITFCPMGDPISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8B7</accession>
    <name>A0A8K1C8B7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8B7"/>
    <dbReference type="OrthoDB" id="156063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="33243" checksum="DE576DD943CAA112" modified="2022-08-03" version="1">MGLHKWTLRFGHGVSAAVVGSARAATEPALKEVFWRKGKQLFLWSTVLIIVIHVTLLPVEWLLGLLLPASWIDTTFRSFRYAMNSTIPFAMVTICRYVKVELFEDAFFAGLKTRDKLVAESIRKHKAIYWDWEYVYHAVRLGARQLTLGLLVTLISPTFGAIVPLARFGYKIRRMERFFWIPVFLAFCFASTQDLALQIVRVWLNSRELFRDLYDPVIARLKSVKTDTSSSLNRQSSREWYDKGSGAVRLGFSMTFACLLQVPFVGPFAWFVAFVAAGIHAPEMINLSAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8I8</accession>
    <name>A0A8K1C8I8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8I8"/>
    <dbReference type="OrthoDB" id="187035at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="45834" checksum="A65FFDB06668525D" modified="2022-08-03" version="1">MMSRRSVQEEYDEEHIEEAIQMAASEGHFEVVQWFHSHFPAQFTSEVFDGAVYAGHLDIIRFLHNATLAKPTNEGFSNAIIDNHLNVVKLLHEEYGSSLQCDSQAAGASLYKMVRYLHIHRQEAFTEDALDAAAGSGTFDVVRFLHTHRTEGCTEYALNEAATNGHLDIVRFLHENRSEGCSTDAMDGAASNGYLSVVKFLHEHRSEGCTTEAMNSAAREGCFEIVKFLHENRTEGCTAKAMDGVAAEGHLNLVQFLHEQRTEGCTTKAMDRAAANGHLHVVRFLHGHRTEGCTTHAMNKAILNGQYAVVKFLKENRSEGFDERILHKADKAYTPDIGRIVKYLALSRPMDQASRKNRADAYLFESSENDSEDIIQDGSGDDYDDEDEEDGKEDGSDLGDHNQDEVDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8U3</accession>
    <name>A0A8K1C8U3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8U3"/>
    <dbReference type="OrthoDB" id="91894at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="186" mass="21217" checksum="CBB6A9A274749CD8" modified="2022-08-03" version="1">MIADNSKSRATDPPSPVIQVRPFQPRDLRQVIKVFVPGVLHYAEIESHMKEFWSDYIDNTLKTDLGDVEGTYFAAGGHFWVATTVVNGEDLVIGSVGLEGKPNREGELRRMTVLAEYRRYGVGRLLVTHLERWAKENGFSKIWLTTATIMPQACRFYESLGYTHTRCGVYSREHPFEVLDYEKCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C955</accession>
    <name>A0A8K1C955_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C955"/>
    <dbReference type="OrthoDB" id="79600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18507" checksum="B438A1AC5B7DA58F" modified="2022-08-03" version="1">MTTAPVSSSYEMDPMLLLLTHDLAKTRHRGTHLNGVYCQDTCRYPSKYCGMARARKSNGSLHRFCEYHRRRANLNQQRWSHQRRMQSRHLPMTPEGEDLISLDSMAPLLLLSAESEPIENLFEEVLKVLSDELVVFPVAGASFANEYPLASGLGSSTSRIAELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9F7</accession>
    <name>A0A8K1C9F7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007299</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9F7"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425203" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="31"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="257" mass="27783" checksum="9C295F52CF8FACA5" modified="2022-08-03" version="1">MVSVYAFAAAAVALISTTDALQGEVIASSLPKGQYYRPTGDLVSGRPTATTPFRRGPCPAVNTLANHGYIPRDGQNVSKAEIKQAVMTYFNIDEAGADTFVNPLPAVFDINQLSVHNKLEHDGSLVHADSYLGEDPASVNRAMLKDVYSRFTPEGVLGVDQLADLRKDRLATCMAKNPNCTFGATQVFLAYGEAVLVLSGFGDVNEKVVDKDTLQSFLEFERFPENFERPDLFTKASLLITAGEIQALVAAKTTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAA9</accession>
    <name>A0A8K1CAA9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAA9"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000088">
        <property type="entry name" value="Potassium/sodium efflux P-type ATPase, fungal-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="691"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="720"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="764"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="862"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="901"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="7">
        <location>
            <begin position="94"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="8">
        <location>
            <begin position="717"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="960" mass="104130" checksum="AA5B41E15F90BB0C" modified="2022-08-03" version="1">MLQVNLDTGLDGSVAQQRLWKNGMNTSGAAKKSSVHISPRIMMMAVVTVASVAFLDFVEMNAFIVVFLLYGIMDRIQTTKTNAILDAMHNTALSQCTVIRDGHQHVIASKLLVVGDIVVLTGGDQVPADMRLVSITHLKANETVLMGEQEDVEKKHAVHTESLTPDNMVFALTSVTAGEAIGVVVATGQSTLGGSIAKRLKGESKMSVIRRLLGTFQSTRTPLQHALYRLSQNLIVAGLGVLVLMVCIRLARGNRDPRRVYDMAWEQTLVLALAIVVSALPITLPSAVAISVICTGISGSLTKGELIAVKVWGDSVEYDITEPVVGSKGDILRDGVSQVKSNIQVRATLLSSALCSNANTQKSLTKSTQTPTDQLWEAPLVVAAAKAGIWREEVSETFKRVAEVPFSSSRKMMITVNELPAGMTFENVPLPADATLVANVKGAPNYILKNCTQYVRANGSVGSLRASDRTSILEAVDELSSQALRVLAVAIRPMAELPYSGDEEDIDIKFESLCQPLIFVGLMASIDPAREGVKDSIKKARDASVRTVMITGDYHKTAVAIAKNIDLLPVGADCDEEAIDCGILRPNGKYLMEHDLDEITSRVSVFARAKPEDKIEIVKSLQRQGHVAAMTGDGVNDAPALKEADIGVAMGIAGTAVAKGASDMILTDDNFCSIVSAVEKGREIYANIQRFVCFLLTRCLGQVAIVFISVAIGLPDALRPLQILVFNVFISGLAAIALSLEKGDGTVMTQCPRPRHQQVVNKRLWVLVLINTLLMTVGALIVFLVGLSWNFGGEVSMNGIMTDILRSDSNKKIRDAVCRRWLGISRGWRDVADCWGLNWRHGLAIPSDVLCYRMNDNCVDDGIARAQAMTFIYLTILEVLRMYSARSLTRSMFWGASANKAMLWAAVGAISVTVALIVIPKVRDIFGFARLEWFLWLLPIALAVVAAVIIEGIKRFYRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAB1</accession>
    <name>A0A8K1CAB1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAB1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222:SF76">
        <property type="entry name" value="MYCOBACTIN IMPORT ATP-BINDING_PERMEASE PROTEIN IRTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="120"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="254" mass="27427" checksum="085B803E3D5F1CC7" modified="2022-08-03" version="1">MPRRTKLKTQGDADEPGYYAAVSPKEERALQDTETIETESNGSDASDGKSVSFSQLFTYADSTDYALMAIGTLSALAAGTGRPIQVLFFGDALNAFNPSVDHPVTPEELRAQVNEVARNFTIAASRQAKRIQQAYVRGILTKEMGWFDVNNPMELPTRAAEATLNFQAGIGRKIGDALFSFSLAVTGMTISFTKGWKLTLSVLAFVPFIVAGSIVYIKLLAKATQAIIKSYGKAGAVAQEALSNVRTVHMFNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAS5</accession>
    <name>A0A8K1CAS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAS5"/>
    <dbReference type="OrthoDB" id="165780at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="20"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="14589" checksum="51E9CA80E8869E58" modified="2022-08-03" version="1">MHKQVPAPVAAPPATDEGTKIVAIGNPGAGKSFFLNCLMGKVRFESEISYGGGLTKSASEVLQNGTIYIDTPGIADQMIEKVAARSVTDTLRKGGVFKLLFFVRLEAGRVIADDLVTIQRVLGSIRGDVMNHFAIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAX7</accession>
    <name>A0A8K1CAX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004824</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAX7"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000412">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20802" checksum="838636B6937CCC3F" modified="2022-08-03" version="1">MGNFLRSALDALASFWSRPSKIVIVGLDGAGKTTLLYRIKNNATVDTTPTIGFNKESFKYKNIEFTALDFGGQTQIRPMWRVYLQQTDALIFVVDASDRNRIDEAADELKMVFENDALVKAKLLVYANKQDLAGCMSVRELESKLNLAAVTRNPSHIQKATVTTGEGLLEGFEWLHKALTGKLSTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB02</accession>
    <name>A0A8K1CB02_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB02"/>
    <dbReference type="OrthoDB" id="74558at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="51"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="639" mass="70858" checksum="416881215413ED37" modified="2022-08-03" version="1">MFNFKLASATSTNGAATAATGTGNSIFNAMGLAGVTTSNGDRASIHAASGEELPAGWRLVSSRNSGKDYYLHIASGHTQWDKPTEAEPKRADGSVAKPTNVFSISGVARMGVGLTSMLNQANSRIQSTLQAKAAMAAPTNKSASRGPSDGGQHVLEMFENERLDGKLLASDPKKFSDRAAAAGSGYDDLPDNSPPDGHEWVSDWDLDQNYTSVDRDGWAYGADFADLTRLLNEESSHASRQPSDAVRRRRWVRYYSDRGSDAHPPSPSVSFDSSRSTGFGTASSWGNETVLDRGGASDNLFADYGEDDDPFHRTAQKAQTGFRVNMKFPHRGGKDNTKDYQSMNLTDVAWLVNDTDTTTAPTDEMMREKTANLEERIKEATKKSVTVEKELRVEHEKKSKELSQQQKKLDALISEYRKVQRENETLQISVSAHRSTVEALRKEATEKDVLLNEEQRALNAEMTAANQALEEKAKALATARMRYKRDNKSLATAVDDAKKRLEQQKAKAESDAQDPLSKDLKSEMERVRKLHAKLEAVRQHRLAIEEESKALFNLVVEKKADLKFQSKKKLETALKEVDEKIQSLKDEQASLTKKLAAKPDPNELRTLNFRRNDIRSELGALKERRTMLVAEKRKQDGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB42</accession>
    <name>A0A8K1CB42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Thioredoxin-like protein 4A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB42"/>
    <dbReference type="OrthoDB" id="147752at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR017199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16441" checksum="216986A741E0CE2D" modified="2022-08-03" version="1">MSYLLPHLRSGWAVDQAILNEGDRVVVMRFGHDHDPTCMQMDEVLCGVAEDVKNFAAIYVVDITEVPDFNTMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAFNNKQEMIDIIECVYRGARKGRGLVVAPKDYSTKYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBE6</accession>
    <name>A0A8K1CBE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000258</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBE6"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02656">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="685"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="730"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="760"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="841"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="869"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="MIT" evidence="13">
        <location>
            <begin position="133"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="806"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="955" mass="107181" checksum="E6C189D9D0538CFC" modified="2022-08-03" version="1">MSEGHDDLEARLRAIREARNRGGAASGTLNTQPPRPASTGALPTQPSLGLEEELEELQSMLSDSTYLPRPTMHETVSTTTTTSVPSAEEDAGVWQDMRPSARSYMEDEPPRVYNRQGSHQRAISVPGAGNAHGEVSYESAFRLIQQAADAERNADPLLAIQLYTDAGDLLVRVGKTENDPLLKQGIKEKAMEIMKRAEELDQWYYSLQESFRQAALPPQLKIQKTQVPRVQESWGRRQPPFANSEEFTHMRYTAVTTKDPYHFTNEGFQLRVDELGRKIRTFITITMYNEEGSELKGTLTGIARNLQYMSEVWGERAWENVAIAVVSDGRTKASASCLDFLTSVGAFDEEIMTVTSVGVDVQMHLFESTIQLVRDDNFEAYYPPIQLIYALKENNGGKLNSHLWFFNAFSEQLLPTYTVLVDVGTIPGPDSVYRLVRTMDRNHQIGGVAGEIAVEQPNYFNPVIAAQHFEYKISNIMDKSLESVFGFISVLPGAFSAYRYEAIRAEKGVGPLPEYFRSLTTSTKELGPFKGNMYLAEDRILCFELLARKGRRWTMHYVKDAIARTDVPETLVDLIKQRRRWLNGSFFAGLFAISNFGRVWKESGHSVPRKCVLTFQFLYLLVQNILSWFLLSNLFLTFYYVLTLVLYKNLHGLLQIVLGIYMALIGGIVIFALGNRPEKRTAAFYSFSFVFFGIVMLMVSGVSIYGLIASVDVTDPRADLSFCKVSNSELSMGVVTAIGLIFAAAFLHGEFTVLLSTLQYFFMLPTFVNILGIYAYSNLHDLSWGTKGLETATGHGPAKAGAGGNLKEIVAQQKRVEAEKQRAAREKEDVDNSFRAFRSSLLLFWLVTNAAWIYAMTDYVSSSCYLQGLSYVVAVFNIIRFVGATVFLIFRIYRRFGGPQSGGDEVSAYQHNLPPEWQTHYAQQRGSMASTHGGHKEQIAIDVQSPVTNYHEQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCV3</accession>
    <name>A0A8K1CCV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCV3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="59648" checksum="5BBCA42D32E907C7" modified="2022-08-03" version="1">MEVDLLTVLLAACGAFAVLLVVVHYVFPQKSTLGELAPYAKYKLPAFKHMAEVLQRFHDYHHWMTELCGQHDGRTFRINMITFDVTILQTPELYEDVLKTQFECFDKGEFMCDILSDMLGNGIFAVDGHQWLHQRKTASNLFTMRTLRDHMATTVQQLMPRVHAIFDKAVSAQQPLDLTKLLNRFTMEGFAKIGFGVELMALEREEDHPFMAAFDRVQQITALRFIRPRWFWKTQRWLDMGAEHQLREDIKVIDTMVLRIIGESLERRQKHTPDVTASAAHDIVSLFLDDISHDEKREAPFNPVFLRDIVVNFLIAGRDTTAQALSWFFYELSSHPEVEKRIRQELNEVWLSQVDDQTTSYTPTMEQAQQLTYLEAAVRETLRLHPSVPENFKQARHDTMLVDGTFVPAGSHVALPNYALGRMPHIWGPDATTFRPERWLDPTSPDKLIKVSAFKFNAFYAGPRMCLGINLALMEMKMFIASVLSTFHLEIVPDQDVTYELSLTLPMKNALVTQIQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEC4</accession>
    <name>A0A8K1CEC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010947</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEC4"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="152"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="224" mass="25060" checksum="26E067C3A5950E2E" modified="2022-08-03" version="1">MAQEDDAAMPQSSLTMEESSAHIEDQDETQASRKYHLHPPRRRVCCVRYGRTTVLYSCSAQYGYFPLTAHIGPNWPCMLVTYAIAIVPMILALVTDKVAYGLRIAMLVTSVITTVIFSMVACSDPGVVFESYEPLATMEDGALQASRDEPDRGVICAQCQLRRPRNASHCSDCRVCVCELDHHCPWTGKCIGKRTLQLFYAFLWCITIHIVLVVVSFALAYISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF07</accession>
    <name>A0A8K1CF07_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF07"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462375" evidence="3">
        <location>
            <begin position="21"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="34504" checksum="B11E593FB83726E6" modified="2022-08-03" version="1">MRVLKTALVLAVFGAALVSGQDDTNSTSPTPTTVSPGPTTLSPTPTTTSPGSSPSPSPTSKTPAPPSDESSNSSAGPTDGSSDNVTPIPTPKSKTPTPTTTPPTAANEAAVVTPPPTLATTSDILLDRSTKSEYGTKTPSSGGEDSVSNSAGDTSNKLGSWLVPSVIGAVVVVALVFVTFLRSKKQDDDYDDDFNPRRSDHFVEHPRTNTNQSMNAHITAAPAPAPAPAPAPVPAPVPEPFYPAKNEFDFESAHTISSAADIDQLSMHSSATGNSSPEPTSMRTVAVGGAIHSPRDRAESNHSTYDDEFDVDIDRASDDFPLSKTPQIGSSVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFM9</accession>
    <name>A0A8K1CFM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane and coiled-coil domain-containing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFM9"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF3">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="77203" checksum="558838BCB0C3CDCB" modified="2022-08-03" version="1">MKKLFASKRATEATEDSRRTSIQSPDNQASIKAAAQPQKRSGSKETGPESLPHHEDAMEFAMKDTLSAPQKRGFCGLTVCLLALVNDGSPELQWSKTYLQVVVEGFLGLPPAQVAAFLPMLTARHDALVDMAVSPRSAQDRKLPPPLMEKLDPAPFLALIVPVAEKESFSWSSLIGKKPKDNNEKEGKSGKGVTSPTLVRADKEAVAAFQLKIVKNLLWFTVKTIGYDARARTFLRILADSVGVSWKKVNEEEFLIGRTLFAEATAMPMEKSAAKLSVWDWKRNATIGAAAVTGGALLALTGGLAAPAIAASISALGGAGVAIGTVLGSAAGVTATTILFGTAGAGVVGMKTDTRTRGVQEFSFDLVSAGDGMNVYICVSGWLDEDDPNSQSFRRSWGDSREYLRAFYRKANDKKVEQVDQVLGRYKGREDEFFAILRKTYRIQEGKAERDPLGLKAASDKAYTTEEETPTTAEMMRAWRWKDRFAQGDQYCLEWEEKLLRKFGKSMRSFAKEQAFTYANNEIVKFTAFAALFAAVAIPRTLLSAANMIDNVWVLMMNNSDESGKILAEALRRREQGLRPVTLVGYGMGARLLFSCLKELTKYEDCFGIVENVVLLGTPVPVVADEWKRIRRMISGRLINGYSEHDWMLAVMYRYQGWALNSAGIGPIEIPGVENVNLSSIIKGHMEYKNKIGAVLDLLKLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGD9</accession>
    <name>A0A8K1CGD9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGD9"/>
    <dbReference type="OrthoDB" id="69354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15565">
        <property type="entry name" value="PHD2_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055198">
        <property type="entry name" value="NSD_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235:SF3">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22908">
        <property type="entry name" value="PHD_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="116"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="489"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="611"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="489"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="891" mass="97770" checksum="5885EC969A74C1C5" modified="2022-08-03" version="1">MTTLTPPFACPVCHTTFSEGEALAPHVLSCTAPSSSPPTASASTSTSTSCPMCHMVYSTALAPHEIVFHEEECERVNQRSEPMDMSAVNGESPSTGGKRTRDGQASTTSSSLKLFPSTCAVCEQGGRALLHCAGSCARAFHPSCIEELNQPPSGPTTASTAIFRDKKWHKHWVCGECTRGLHACQLCGFLGHESHDVVACSVNDCGFFFHPTCLQEQQHRVQQPLVCPRHTCTSCHALETDMTTCRSCAQCCLATHLKCQDGASTPSTELVNTHVYTCEKHATDTTPTLDERKKRFMGLKLRVHPGDVVLILDYENGLLPEDTKDVAPGSHNFWGVVQKAEDVVTDEKSGITGWNQLLEVEVFADNSTISVLNRYVLPVGSMHGFKWPEEMVRDAIQWHSQCESQLYQQELLLKGFDIRTNDMKRMNALVGSWRAFYGRVQPPYMTTTQCMTIAGRGYASWKEHYEAPERVYGRTPAPVYLYLNTRGKDKDDDEAAETKRSEVVTTRGRGTDDDVEMDDTGSNRPSPAKSSSFTPSHGGSAASTPGVASRSLSSTESVVMSVLDDLLSQVMIQDEMRTEVDVADAVVAMCGPELSKVTPHRVSLPAYPTDEAMEEDTPSTHKKRTASAVESEVRKQPEVVDISSDEDDDSDDDVVIVPPTPKKPKVMTTSNKPRPVKFELLPTKLRATSSIFGRTPLSVPSPLKRKEKTLAELPPPIMAEIEDQVSKYFESGPSTHEPPMPSLRPAFYRPSPMLYRGPRVGRTVDAISRVLLCQDKRNLKCFVHHVTDNQALPPSCPHGGRASYVAVDLLGVSTFSALESAVQSRVSAAFGPSTHPGERWRSLAAQKSPQMALYYCAYDGSQHELATHKPQDPDWLCFCANVCHLTAVLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHB7</accession>
    <name>A0A8K1CHB7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHB7"/>
    <dbReference type="OrthoDB" id="128410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="677" mass="76563" checksum="B8EA10BBC00C5A0F" modified="2022-08-03" version="1">MSPEDAIGRVENHPKEPTSEPIDSYRIQRERLERMKQRYMELQRAMGRPAEQEAARPMETKAPPPSPALPTITRRTHSQEPRSAYELMGNQVDPIPEPPATHSTWRREDPDDILHEFDEIMRRSFQNEHAEPTSYTQESTATDTPPLQVRAPPATSFKEEISRSPSTSVKSFGRYDAEPTVDADGNPYADQRLPTSDELGVHAPFSSDYDSIPEVSFSPPLTPVPGFAKRGSSNQRSNEGRQSRRSSSSQQATAAQEHREASSSARSIAMGGEVFPKWSLGFFAGCLVVGLGGFFIDEIMDVAGVALKSTPFVITRVEQREMNHRLEMLQEELLSFRVATATIELQSQRMVEEVRFHLEKMKLERERHQAMVAIEMESLRQYVHSLTFELVEQEKKEIRQRLIETIAESIEELPENLEDDDANMTAETNQKEKQPEMTREEVIPVDGTLEDSKAASVIVEPVIVEPATVAVIKETVPRLVLDATPVVLPASTAAIAQSGRTSVSWEVFGMLALLALLGGFVALRVRKSKTRQKWQEYTRAWHLHMPHVQLQRTDDVTDAVSDVETVEFMASSEQSHGEEEDDEEYEDSEDMGRSYVEDEYEDTEYTESRSVTSVSDIGTEDLSQSAYSEREVAEYDTEEVEEASSAGESTPRRAKREQPSHRRNPRLQMRSPLVYMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHK0</accession>
    <name>A0A8K1CHK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002296</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHK0"/>
    <dbReference type="OrthoDB" id="10259024at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="10">
        <location>
            <begin position="285"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="818"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="625"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="639"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117969" checksum="3FF2B179B6D0C7E1" modified="2022-08-03" version="1">MDPGRRHSGAGAGNANVTPTGSSSTNTFFNPTKLLKKGWSGVTSPVAAMKDAVLASATPRGTVFGMAGMASGASTPSSRNAMPAPSEYPSLFDVRAPAPLESLTLPHRQSSDSSSSATGPGGGLLRSGSASSDVAHSSRTNSRTASASQSRESSLRRQHLSSSSASSVSAVEDIASMDEEERAYLSVFHHNLHSVLTNPKSNNWGGAMLDLLYQNPLEADIPLPSLSIPGLDLVGARDFDPYLKKYGKLAKLYEDNHALPISEQLSSSQVPSISIADEDVAKCLNVVPSFFFRPDFDLTDPATFEQVMSMKTSLSLQEELSGYLDRVEFTLLRQVSSRSDRFFEASANQEVMKQSITVACDQVATLRKTMDRLRNGLADKSLDIVSLHRRQKRIAELHEVVTMIEGVKNAESAVEALVQCEEYTSALDLIENAQTTLREHLKGIHGLSALSDKLQGYRGLIASQISQRFISIVTSPDWMFEDDEEAPPTTTKRPHQRKYSTGSDVSVSDKEVSTAEMKRLVEVLFRLDALTDVVGKYRDQLTEEIKVVVKTVVTETIAMSDSSKSNGADGSSADSKVSIQLRALSSDEFLQCVKMIFEHLLMILERAVVVQNVLTRAMQKKIDDATAEEHQAAKEQQASTEVTSPTGETWTPTESITAENEMLGDWKKKSRCNKVIQEIDDVLRKTCEFSQRSVSNLFAVRKEVQAVYTMPQLRLLYDTTMEFVVNIEKLTTKTDYTLRGSLFSQLKLFLEKYHQTQMAKLVSTLDHELWKNTEISVARHKALEDLSSGRGVSMMLSDDREVSGETASPLKAVSVCGKTFRIVWSVLLMLEIVMNYMSCAANFPVLATDVLQRSIEIFRLFNSRTTQLVLGAGAMQIARLKSISARHLALASQSLELTMTVIPHIKAALAAHFTDRQKLLLDEFDRVLRDYAEHNEKIFSKFTNIVEDQIMKRFLENVHANVDYDAANLSVPTNPMKGIKDSTLKLHAVLSPVLSPPQMKDVMTRVFDMFTQKLPECFKQVKPKSAAGKKRVVEDIALFTQSFVEVTAVEFDGDALLRHFKSVYDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHS4</accession>
    <name>A0A8K1CHS4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHS4"/>
    <dbReference type="OrthoDB" id="166170at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="340" mass="39238" checksum="895B61B3DD4E3839" modified="2022-08-03" version="1">MVTPAIQTWRDRLRYELTSPYGLLRQYYNPVLDLPKLLFQTATLVTYLHNGFPVVIISIYTSLLCINWMISSYRYKQWRPDPHYVLARLFYSGKQPSWTTRRRHVQNLLISAVFFCVGVAVFVYSTVAMASTKHVCHAYQQCAVTRLQWNVGATHCSCIEFVDRTTSVKAFAEWENPPDTTANLAALATTGHLRIIQIINPALPEFPEELRGCHDLEQLILIYTKTVRFPSWAKEFRHLEYLHVEGDFMPTQLISLPDDLFEDMHGLVFRYLGGLIKLPRVPDLSRLTHLQHLTLAVLHSITEIPSFDTLVNLRMVTLMDTVQVQELPSISKLRHLQSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIQ1</accession>
    <name>A0A8K1CIQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIQ1"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="225"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1007" mass="115415" checksum="7A0F84327D744FDE" modified="2022-08-03" version="1">MFRQPALASSAFAGLHDELLAYWTLFCDTKELLALAEVNSVFHVFAREEPLWMLHCLRVHNGDFTFHQTWRLTTFFPRPERVPATMPTFAPMQIRNFGSDFLYRRWCRSHMSLKHFVPPPPEDPYARRVKRIDVNDMTYQEYFEQNSRVPFVMQNAIAKWKAATEWTMDKLVARFSDPPVCHRVTHNLDTTHDKSTDINFSDYQKYLTQQHDETPLYIFDPRFGEKMPSLLGDYNVADLKFFREDLLKTPAVSTAPSTDGKKKKPGCIDPDFRWIVIGPERSGAPWHTDPARTSAWNALLQGHKRWAIYPPGCPPPGIKVGKNAAGREHALNMTSLSWYLHVYPTLAPHERPYEIVQGPGDVIYVPSGWWHLVLNLDETIAVTQNFVDSHNLPMFLKDLLDDQHDEALRSLQQSLRVKRPETFDVFRLAQIPRMHGYLDDGLYVSSFGLLHHWKGHLKTVLKRHHLSYAELRKQAPIRSLTARANPTFALGDEFVVKFYSELNEDWGEFDLDAYLSPPFDDETASDTEHSSKKRKTGVLQPHQLKTYMSLRYAMEECYRIETATYRMLMGDNVPSGLAEMIPKLFHASHLLDVSEVDDADGEGTMWRWPYAVIEFKKGLTNLNKLTARGGATVESWQRLASWLNHEFVPRFHAVPIDKELRGVYGHSKAQWDWYAHYLLRRRKQAMTFHMQEDAIPPQLINTLEAFLLPATHDVIVDNVLPPWALDGTEPPVLLHGDLTDENVLGTLPSKANSTLQTRNKPKERVDVGIRELLASVDCAKYIPLLVDQEELTCETLRMLTETHLTDLGLPLGPRLAILNAVAHAQGASIGASDVVAVEEEEEQDDWEMCSDNSSDSCSDDEDDDGENLYFLTETQIEALRTKRQSRFYGAYEWTPTQVIDFADSKTGDPLYDLVAILFGALHCDRDLWRVTMAAPYWQSYLRKEQAARGVDAVTLGRVLGERFLRLVLLHPSRSVQGLFHFLPEANRFMAWSDVAQFVFGNVFVPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA9</accession>
    <name>A0A8K1CJA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pectate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJA9"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18087" checksum="C34CDC6433BB5BEC" modified="2022-08-03" version="1">MEVSSSCDGKVVSGIKYDNAGKKGGLVVGSNKTRISMYNNVILAMSGRSPKFGGSTDANVVAHVANNYFWDNTGHSFDVASGAAVVVEGNYFKANTKPITSPIEGSVIMSTASNVNSCSSTLGRACVANTIESNGALASKDSDALTKAKTIATTYKPSVAKKLAYSTTNWGVGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJQ9</accession>
    <name>A0A8K1CJQ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="3">
        <location>
            <begin position="2318"/>
            <end position="2368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="964"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1273"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2420"/>
            <end position="2442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="264"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="380"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="515"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="701"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1357"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1904"/>
            <end position="2201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="964"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="975"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2442" mass="275367" checksum="8DB8B13986CE4B3E" modified="2022-08-03" version="1">MAEVPGKEALSRELQEERDDAAVPVERSQKMKQENQVLLKKLHDVVGRYRKLQSQHQTLVEKNETTTTMTANGDSKSAEASPTNSAADGDNAEASAQDAVVKKLETEKHELIEKLKNVVGTCRAMQKQLQEAKEENEALKSPGKPLLLNADSDDRASWGEQYGSMSARIRALEDQVSEKDTEKEELAGKLKEVVKRYQGLQVQLEEKDGEIARLTPKLEKLTAAIAHEEAMTALFREENVSLKDQLGSLYQDQQHREDDHRVHLELIEKENTALAAKTSELERDIAIMRKEQDDSEQLYLEVASKLNQTLRENGQLHERILKLQEAAGESQFLEESQRRVQELEEQVSGLMGREEKLVKLEAYLEAAGIGSTFATIEDLISTHTTKIQELQLQINELNEEHQSAVTVCESRSSEVESLKAELEMFQEAHKATSSDAIQQLEAALREARENAQKSAQQVSEFQRRTAMLQSDLDSTRVELTSQTDTCKELKSQLDVIDMKHETALMEKDQEHWAMLSEAEDRASERSQRIQELQQQLETLQTQISENEEGIAKKDESIAELQVQVSSMQSDNETLRSEYDSALERLQEYKSDLAEARHGLEEYKLELSASQQSRDAMKTELAETQHELEDYKAAVLRLEDSVSERLTELDDVRSEQMQLRSEYDALCEQRDSLSMEHADTVTKFQHQVNSLLAEQVERDDRIKELQTSEQARLARVKELEEEVQSVSAALSEARSYLDNQLLGVTDERDSIAQQLGSMQLDHEKLVAEQERLTVLVGTYEEEWRSQKDLLMSKEAELNDLVSKCETLEANCARLQEVQTERDSLSAKIDELESKLREHESELNRRGEELRSAIEASEAQLSDRDGEIDQLRGEKANLERHVIEWKSKFEEKLGDADGQVAALTVEITALRTKIQESETEIAACNQKIAEYEEKMVATSAKFKEDLHQKDSEHEHLVSELHEQAARLQEETDDLRSQLESSKNHAQSHSNQIEHFHVSLRSIIATTLHKDDNDEEHDSSDATSFESMIEQLRSALQQARENETQAHALSGSLDAIKEKLESAQADLSLAETRAEQYEAEIQSLNDSLQATKDENDRVLAELESCHTKLTEREHAIEELNAVLSRVQEEKEADLVVAASDAAKKVEEMARQLSEMESEMEAIRAENVRMVFEVAKTTDSGVKLQQDLDSLQQELQSKTAELEHQIGVFQDLSSEHDRKTKELEESLALLDGAREELVTVKRESSKEYQLILEQLEASTQTLDRLQAEFGTTQEQQDALKQQLEESEDKRKQAETLMEEQMSSFSEEKRTIEEKLKAVDTEKQALADEILRMQTEFTQQTNELETHLDLKTSELRAVHSERDDLVSQNDSLTSDIADLKQEIEAHQTTLDVQSSEVEEARKALRSRVKELEKKIKELEKQAKQEQAEKEKVEAALRECEEKLEAATSSSDESLREAQAQISELTAARSKIETDVLEFESRVEEAERVNVTLQAEKEKVEAALRECEEKLEAATSSSDESLREAQAQIRELTAARSKLETDVLEFESRVEEAERVNVTLQAEKEKVEAALRECEEKLEAATSSSDESLREAQAQISELTAARSKLETDVLEFESRVEEAERVNVTLQAEKEKVEAALRECEEKLEAATSSSDESLREAQAQISELTAARSKLETEISEFETRIVRATAEIQASKQTSEALEVQVAELKQRNHHLENQFESHASSIAAESTAEVEGLQQKVDSLTVELSALRASSSQQESQVAQRDEIISKLKSKLEEVVALYKKLKEHAKELQDRYTEKSEAVAQIQQEAEELKGMHESKSEELSLLRMELTSQKEQFATVTNQLQTATEQLSRAEQNHSDEVACLRQRVATCEADLVAMRNERALAVSERNELIETRKVEEATWNQKIVDLETQQSTLVKQVQDKEAEGQEVLDKMRELLTRYRELQEEHAKLQSSHEETRGDHDMVLVAVREELNQAKVEIAQLQAERDGVGVQYEETQNKLQAEVASLRSQLDIEIEGADAARAALETYKKRAATALKKATSESKLSVRKIEEETSQLQQDVADANARIEILQIELSNANALLDEVRSSTEDRVRVTKEQAQKEHAAVNAAWKERVSRLEDDINSLRATLQAKAHLDERVEELNVQNDILKKEIEDFKDQLAKKSDLAREMLTVKDSEISDLKKRLEVAIQEAEAAAAAAKAASAAAAAASATQHTSVHVETVQQSEVVHEEHHLSAAVAEVRSIPLASTSNGASAGADAQILKLARAQALRDEEAGKMKKQLSALDEQVRLFQKKYEDTLALLEETNRQKKRLQELNSRSSDGLNLEYLKNVVIKYIESQNHSEKERLIPVIATVLHFSPQEMRKINDSHQRAQEESGGLLGGMFSLFGAATSAPPPKPLAIPANLNAREQTTGMIIGGGPMGGDQDEDDDSAMPLNPFAANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJX2</accession>
    <name>A0A8K1CJX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013051</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJX2"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21504">
        <property type="entry name" value="PPP2R3A_B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.220:FF:000003">
        <property type="entry name" value="Phosphoprotein phosphatase 2A regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000025">
        <property type="entry name" value="serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041534">
        <property type="entry name" value="EF-hand_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17958">
        <property type="entry name" value="EF-hand_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="658" mass="75470" checksum="EFDBF255C296C89C" modified="2022-08-03" version="1">MAQPAGLAVDTEAADAAMPSPSSSIGRTDPLRLSEIESAHLCPSGRMKMEELFRQWLNVEGTKEMISGLVEDVRNGKEVNLEAMMVSGSFGPHSGSGADMNSPARSPKRPPNYHHFGANNSPSPSSSASNSPLMLARKKNPIMSLFGQDLQLLTELEKQETPDVVMNETEEAAPAPSENNNEEEKMDAPPPTTSPQIPRFYIPGESRRGRLRTFSTDTIARKASDIDGRFQDFPDGMKVEDFVAITKDLCGFPSFFNAPFFRRILAAANNGELPSPTATDDSLKITKEMFLPYWQKELAPFDDVERFFRVVKQPQNSFIERDDFAPFLHELLKYHPGLEFLAGTPEFQEKYALTVVVRIFYSVDRDSSGKITLRKLRRSNLLESFNTVDEEEDINKVNAYFSYEHFYVLYCKFWELDTDHDFQLSPDDLARYGGHSLTRIIVDRIFEHGRRPFARVQNLTPEEKKKMSYEDFIYFMLSEEDKSNPISLQYWFELVDTNEDGVIRSDEMRVFYRHQMHRMECLGHEVVPFEDILCQMSDLLHPAVEGEFFHKDFIKEDKIRVSGVFFNVLFNLSKFIEFEQRDPFLLRQQLAEPELTDWDRYARAEYARLAMEEEGREDDSAMDIDTMDGWYVSDEQEDDAELMVSAASTANRTVEAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKY5</accession>
    <name>A0A8K1CKY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008066</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKY5"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035465149" description="subtilisin" evidence="10">
        <location>
            <begin position="28"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="175"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW65424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="459" mass="48329" checksum="B4A35AEF07CD3C4D" modified="2022-08-03" version="1">MVRVSSTVLALSLVVGVLLDNIQDVDAAATRSQRRTNVIVTMKQRTTTVVDSIGSQKFTSRGQRVKAFKDGLEGHARTSQADVLSLLDRAGKTTFSRTESYWLTNQMLVAGATQELVELLSMHPDVASVAPEQIFPLVHPVLETAAISIPPSSASTQWGVKKINAPAVWATGNMGEGITIGIIDTGVRATHVAIKGNWRSTYGWFDPEKKALTPYDATGHGTHVTGIIAGNNGIGVAPNAQWIMCKGCRSTGCFSSDLLACFQFMTCPTRPDGTGADCSRMPRVVSNSWGGGKGLTTFDEVINTWRKAGIIPVFAAGNTGPSCGSIQSPGDNANIITVGSTDSLDGVSRFSAKGPTTKGLLKPDITAPGSAIKSSCYTGDTDYCSKSGTSMATPHVAGAIALYLKSKPSATYDQVKQAFQSTSLVVKTATGYTCGGTLDSTIPNNQFDYGRLDISKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL07</accession>
    <name>A0A8K1CL07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL07"/>
    <dbReference type="OrthoDB" id="156202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443566" description="Apple domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="50"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="209"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="29396" checksum="8A269E527635E4B2" modified="2022-08-03" version="1">MKLLATISLVIAITATATTVDASSLRSVNDTERHLAKMEYMAAMAPTPNCVIEHGFDYIGYDIKSVQGQPVENCCQACATTDGCRAYSWTNQNGGTCWLKSGRGEIVSNPNVKSALFSTTANNNTTCQLANDLDYVGNDIGRASASDAGQCCDICQKRSGCRAYTWTGQDGGTCWLKSKRGETTYKAGAKSAEAYPVDSGNNSPPPAKCDLVKDVDFVGNDIGSPEPGATADQCCTICKSRPACKAFTWTNQNGGTCYLKNGLTTMASMPGVVSSVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD1</accession>
    <name>A0A8K1CLD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008993</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tdpoz family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD1"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056423">
        <property type="entry name" value="BACK_BPM_SPOP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051568">
        <property type="entry name" value="LZTR1/Attractin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376:SF1">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24570">
        <property type="entry name" value="BACK_BPM_SPOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="336"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="491" mass="55580" checksum="CC0A2B3BA2D40976" modified="2022-08-03" version="1">MATSPRPAARSWFTVPCENPSAAPCVRALHACAIRKDSLYIFGGYDGSNRLNDFYEFNFTRKIWSVMLAIGAPPTPRDRHVGVVYKDSFYVFAGFDGTSRVNDFMEYNFLTQKWSIVTVNAGMAPTPRHSHSAVVYDKSMYCFGGYDGGYRNDFHEFNFETGTWTLVSATGRVPRPRYRSSLVVHKNSCVLFGGHDGSRHLNDVFVFDFAQRAWTALAIEGPDPIPRDSHVAVVYSSSMYIFGGSSGTAMNDFYELNMETSQWQAMPSKGPPPGQRFCHAAAVYDSSLIIFGGYDGSSRLNDFKQFRFGQDEFELDIPESTLIPDLRMLVNNQIMSDIVFIVEDMPIYAHKILCMRCGYFKAMLTGEMLESRAREIVITDIRRPIFLAFLEYLYSDDIDVSVESAMELFVVADRYGVDRLKRICERRMLQSLCVDNAASILHAADLHNASVLRDQCLAFMLNNFDAVTKTAAFEEMGRTNVDLVFELLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLP7</accession>
    <name>A0A8K1CLP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLP7"/>
    <dbReference type="OrthoDB" id="76516at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="200"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="312"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="481" mass="55093" checksum="6872E9E419373458" modified="2022-08-03" version="1">MMTLGLLPRAGAFVSDVLRQEEQRLMEQRAIFSEVHQVLDEMVYDVETCEYECEIVRLRRELQETQTALAESQQRESELIHERQQAYAFAEKVEQDGRDILTKLTESLGVVMAELAKKDRIELELAQAKEQLQLSAQLSKELASAQREIRELHQRSSIQSLLKTTSTSNKPPPVRIPSPSRKPATTRMPSPPSNQDEVNSDRFADCPDKLLLNVFAYLDANSVFALSLTSRTLMNRVHVIFGVPSTQVTTAIKDRPAKPPSPSPQRPPLKARSQSAMVSSNDKAQQLAKAEMIVKSLKKDEIKLFHDMSTRVRSLEGHLSQTQAEKEDLAARLHSAESVRDFLMEKLQELEDRLAVMMEAMTKKDEQATMDREIIGFLDAKSQEYELALAKTSKQSTDVRQELDRMKEEHSMKMAIIQDMVSLLTDEKKDLEVQLRSQRKVLVREVKTLRAQNEHLVDERDHYFQQLKQLRHALQHLDELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLR8</accession>
    <name>A0A8K1CLR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLR8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="123" mass="13955" checksum="E06F7D6484D596AB" modified="2022-08-03" version="1">MEAPVAEQLQALSLETEARMQIEDDMDSQAGIKREKRKLEQEFAVLEKVVRPTIKKLKELDEMAKVVTAAVNAMSEVCTSFEANRAQCEANRKQIRALYAEAARVTKGIRQAKRKLHELDARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMG3</accession>
    <name>A0A8K1CMG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMG3"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03886">
        <property type="entry name" value="M20_Acy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000001">
        <property type="entry name" value="N-acetyldiaminopimelate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014:SF63">
        <property type="entry name" value="METALLOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PEPTIDASE M20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="481"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="705" mass="77410" checksum="B127E0BD96321589" modified="2022-08-03" version="1">MAETPTPAALAAASTPDSKAKMKQGAGKRLNDKQRVEIIQLAENSKISKRQLADKYGVSEAAIRKLLLKKDEFLQRYYDTPEEIRDQRLRGKSTRLSQEFSSIAHATHASDLVRDGVTGGVGSLTSSLDTTAALFAHTKSLYPQDDPWKHGLSVLAGKVAPFMKNFAQGKQQRDVSLVDATDTDAVIVAERQDAALAAAEGATAMDLEGAVDMDQLPPSNVDWLGFARMLRDIRRAFHRYPETGYQEFRTQAFIKKFCESSLRIPGKNVRVMASTGLVVDVCYENGTISSSDKRKLPVLAFRADMDALPIEELNDHLPYCSTQKKQRKDSRKRKKRKTGSATPTKAAVDGTESTSLEVGGPEPDLVVEVPVTPASSGEIDDQDEDDSGFSSPAAHMCGHDGHMVMVLGLLALVVRQAHLLPQDTFVRFIFQPAEEAPGGAERMISEGVLQDVDEVYGLHNYPFPLYSVHVRPGPVMAHEVEFTIEIEGVGGHGSAPQNCVDPILAGAMVVQALQSIVSRTIPPTESVVVSVTQFRAGDTNNVIPAKAVLGGTIREFDLAIAERVKQRMEQIVHSTCLAVGATASVHFAESYPPVVNPYEETRLVQQVAIDTGLYVSEEDLPLMAVEDFSYFLQERKGCFFFLGTKEDSDDPKTRSLHCDHYDFNDKALPLGIRVFIGVLQSRLQCQLYNIEDLQEFQVAMERIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CML8</accession>
    <name>A0A8K1CML8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CML8"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445646" description="Apple domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="735"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="697"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="710"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="877" mass="92026" checksum="5D4BDF8C700F4546" modified="2022-08-03" version="1">MRIPRVGALIGALAVILPAIDAQAYDVVIVGSGPGGLVAAEYLSRDANVSVLILEAGLPSLQATGGTDGPSYASSKGWTQFDIPGEFDNTIYNSANEKYRVDFVTGPYMWLGKLVGGCSSINAALYFRPPDSYVTNTKWPFSPSRVAALLDENEKIHDATDAPSADGKYYLQEAYNIVANAFKKIGYNEKTINDPAARNAKSQTFGHAPYTIKNGLRDTPAKAFWNLMKTRSNVKLVTSAMVSYIRQYQGKATAVVYNTNVEVPLTARGAVIMAAGALGTPKVLIQSGVGPQDQINLLNLRGDFPGVKNGGWVINNNVGKNLFDTNVVFASFSHPDQKSFQYKTKPSWAIDQYMNQGQTGGWASPGPVLIGYENYQVNGRAYEFQTTVLTAGFDTFYSQGNAFTTSLYVNNPEARDYSSFSADGKWNAFTQNSMYLATGNDLAAMQNYATRVVDALRANGATFLSAANGQSVADWVKGYGGRITHHFGGSCYASSDTSDSKRCADEKLRVIGTSNIFVGDATAMRDGTVNPYGFIMYVGREVGDQVKSYVASGPTPPPSTCTIENGVDYVGNDIGSVLSATAEGCCSICSGRSGCGAFSWTSYGGGTCWLKSSKGTTKADSSVRSSVISSTPTPPPPSCSIEENIDYIGNDLASALSSTAEGCCSICKAYNGCGAFSWSTFNSGTCWLKSSKGATQTSTGVRSSVVGSTTPPPTPPPTTPTPPPTTPPPPPSSQCSAVEENVDYTGNDIGSAASSSVDGCCSLCAQRSGCGAYTWTNQSGGTCWLKSGKGGTTSKSGARSATYSPDGKTCSLTNDVDYYGNDIGSALSSSASGCCSICRSRSGCAAFTWTSQDGGTCWLKSTAGSAVAKAGAVAGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMS1</accession>
    <name>A0A8K1CMS1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMS1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455032" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="190" mass="19703" checksum="F00902F9089FDA12" modified="2022-08-03" version="1">MTRILTSLAFALAAVSTSRVAADEKFEETTVDLAYQRPSGDGPICIGVTFVAMYPSQPVEGASLVINVTAIDTPAGAIVRVRDCDSASNPALMNASDPATWLAAVSGQCALIWLNNTETPLNCSNSKVTAEYSLLSDYCERSPSAEVCRSSKAPSSQPVPAPSSAMPQTAGAWAVATTALTAMALSLVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMT4</accession>
    <name>A0A8K1CMT4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMT4"/>
    <dbReference type="OrthoDB" id="568502at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045931">
        <property type="term" value="P:positive regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042481">
        <property type="entry name" value="CCDC57"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46725">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46725:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="545"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="849"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="954"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1059"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="357"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="446"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="910"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="959"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1091"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1116" mass="127139" checksum="E0CF8D878A11CE49" modified="2022-08-03" version="1">MASMPLATSAMAAAAASESSLSPPPAIARVSPGNIRSLILEKEKELHDINEYRIRTLETLLREKETAAHAYKQKFNKLQEDFKYNLKLLEGRDEELALYDTNFASLKNVLRDREAEISELKAQVADLQTDVKQEQKRASEQEVFFQQKLKDARAQMEGARWNFDDELRRTRDEMEQAKRRMERQMREQQEDLETQRREITLTFDDVMRQREAEFKQTVDELQAKTRELELKVKSTTRESEMAKERCEELKMKMENMQKMLNESEKEAKAMEWQLSDVRASKDAKIAELEDEILKLQEVKQSLLDEYEGKMAELLQSLHSVEKAFVQQKAQYEDDLQRFIRKKETDSQDMSLRMDAKMQSLMAKLRDKEELCEKLQADIKQATWESEDKHLEKDREIERLKQEIQDVEEQKHSAINDMKQQLWTIEREQISLQEKMKEATLQLQMNKEKGKLQRQELNETVEKQEDLKREIVTLNLRWENKWQEHEQELSSRHELRLREVQQARDRLLNEKQATEDRLVHAENELHRLRTEMLTLKSNARINESFGNGYANGTRGSGNSQHQSSARGSREDSLPAPSPLWSDDNGTLSPLPNMSPMLTQSPQQHSTNRDSAMISQNEATLQAENAKLRDLIRQMREALSEQAQEVAASISPSGSGDQADTLKRLSLAEKQCVLLEAKLHDAEAKLRYPDASVDSSALKEMNEKLTLCQAELIQANRTIDARNKRIEELESQLKELGGSSGGSGLAANLVVTDVQVSELKRKLSSAHSDIERLVKERTQLMELSNQLTSELRRFKETSPDENRATNGKSLDFTGKKDYENLIADLSRSLEEARVNNKTLKKELRRMVKLQVLSQQQAGDGDGGDNTARSRAPSMMSTDGDTNTEEANGPRRHRSSTLSMMKALETNADSRRSSMYSVASSAQPTSVRGSGGEGSRRDSVNGVFDEELLSLVRNKLSSPVPTAGTTRRTTTRASTAIPQTIPEHENENDDAEEKEEAKIAATRPATTNSFNGSEVGGQTSMRMLFSRERMDSMDSVGESTAKVSDARVRLQQAKEMLLLAGKKAERSTSLASFASAPAKLSDRETPSQKSAIKRLKELQTKRAEMVQERKKVRNYSMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMW0</accession>
    <name>A0A8K1CMW0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000023">
        <property type="protein sequence ID" value="TMW66561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMW0"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40850" checksum="878665F302FC6EE7" modified="2022-08-03" version="1">MAGGMRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIEMNCLDAEEEHDFQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVAKKLREEIATMIPELVEGKIKVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVILAYALARATHVWGPDATEYKPERWVDETTGKVRNESAFKFFSFNAGPRICLGMNLAMLELKLVLTSLLTRYQLDLVPGQTITYDNALTLAVKGELFANVNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNY1</accession>
    <name>A0A8K1CNY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNY1"/>
    <dbReference type="OrthoDB" id="72921at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425206" description="TRP C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="TRP C-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="440" mass="49342" checksum="59ED8F592EDF8A76" modified="2022-08-03" version="1">MSVLLLFLFHFASLDPSLQWKRLAWSPNTWEFCVYVAYLQQMASYSQLTMTKSPYFLWDFTDGFSWTNFLMHQSIPSLRARRLKTVIILDGLVGYADRIGINESAILLHVISGFAVVVAFFATIFCTSAMYARIKSRATRDSHVDEYGVWNIPYRVLGLLVLVWFFALYPLCVMASFEIYMEIHASLVAPGSLVAAIIALVVVCAFMLAYTMRTLLSKTETELRQYKMIAIWGVFYLDCWFITRLFFVFGVFFQIISAICIGVLDSNAFLLSILIGIQVLNLIAVLVVKPFADRLVRNITLSVQVLKIINFSLGFAFLQGQSLPSSERLAIANAFIGINTLVIIAWFVRLLVVFAHALSAFLMRERVGNGSYSPRESPDSGGLEMYKFAATSTPEIPTGRFTGLQSLSLSSAQESATWSYYLRDCSSPRPLPGAVLSPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPM1</accession>
    <name>A0A8K1CPM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sphingomyelin phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPM1"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09078">
        <property type="entry name" value="nSMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017766">
        <property type="entry name" value="Sphingomyelinase/PLipase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="4">
        <location>
            <begin position="36"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="429" mass="48001" checksum="100ECDAB9B9E1426" modified="2022-08-03" version="1">MTETERMPTIRERIAVLSVNMFIRPEGIHSGKWFGSGDHKDLRTSLLLRKIRDFDIVILQEMFEVGIRQRHFVRAAYDLGFKYHAGSVWPRLTDRFLIDGGLLILSRYPIVERGQHSFSLGSGSDGVCSKGVLYARVQLSPDLADSLHVFTTHTQAGDRLKEYSIRAAQLKELQQFVAKTIREDPYAPLLITGDFNLDARHDLRHDPATGDVYSTPCEESQVYQTLYSDLHGVLAAGRTLVDLMKHHDTTKLSGHIHPITNGDGHATLYHESDPLSEEKIGKCIDYMFFSPGVRERRSVSGDIPTLHLSVIPGKTDVDHGDVAAILLATDADTNASTRFPITHLSDHYALRGEFELEVTPVNRPDGSPPRPGQRLYEILQLHFPPKAFTQRTQHLWQWKVRIALLAIALSSTSLVVVIGQTLTSALGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ78</accession>
    <name>A0A8K1CQ78_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ78"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="190" mass="20811" checksum="3B45866D2E0B1895" modified="2022-08-03" version="1">MEIPDLEKVVAAMKSWSDSEGMWEEKPGASITKPSHRTTTPDLVTRLLGGEAAFASDDERVVERIAEFIQSESFKHVLILTDKAVPQMTDLLLATIGECSSNIELTVVSYDDQKRAEPMSAESNTIPTATTRYDACVDLCCSEDSIAEAVVMTRPLGTIVLLTRNGSKSADAIPIDMNTIVVHELRLIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR99</accession>
    <name>A0A8K1CR99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005844</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR99"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PX" evidence="5">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="308"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="341"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="374"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="407"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="528" mass="58981" checksum="A7E57B534BF3164B" modified="2022-08-03" version="1">MEVPTYDCARHQHRVAYEVVLFKQTTSVNGEVSTRRFATKRSYSDFRGLWKLLLRLTSAPSESSKQRPQQRWQYMFHGDTCGCEGRSTSCPFLGLHTVLDETPFPPRKFRRGSDATIETRRKELDNWLTTVHRYFASFSGSLLFSKLRREDCAVLRAYTTFVGAREHFPVQNLHALQRPLALKAWRAKQKEAAEAIPLLEADDIPESAISDEDSDEDEMVILGPDDCHRLPRLDVKPVGVKTMQTFLEDFCTHLLANFAEDIVELQAPELTEARRWEIALFVACRIGHTYGARLILHYYAHANVCMDDETSCLHIAARTGRQDIVFMLLSHAADANKANINGITPLIAACRNGSFEIARMLLNAGADISGCSTRGTRPLHAAIVSNSVEIVELLLKRGADANIPTSSGITPLHFAAKLGSIVMTELLLKHGADPEQQTNSGSDVLEIATIHGHQTICEMIQQDLERKRAPILSSRGLFRKLKLTSTGTTAVRIRSASQRRLRSPSLLPPSSSDTVDRLHTLEPPLLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH4</accession>
    <name>A0A8K1CRH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRH4"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004354">
        <property type="term" value="F:glutamate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000002">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000030">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.285.10:FF:000007">
        <property type="entry name" value="NADP-specific glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.10">
        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="252"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="54299" checksum="82B447AFE1518A76" modified="2022-08-03" version="1">MLLPTLLRCKPGPMTSWGARAASSLMSDVHGTTHGKKHWRNKPLFRREGDKKFRNGQEAADMLVEEAARRDPYQTEFLQAVETFVNSVVPVFDRYPKYAWVMKTLMEPERVIQFRVPWIDDTGNQRVNRGFRVQFSSSMGPYMGGLRFHNATNHGTAKFLAFETVFRNALAGPFGAAHGGADFSPVDKSESEIMRFCQSYMTELANYIGPHTDIPTAGVGVGPQEIGYMFGQYKRLRQLHPGGTEGILSGGLYYYPQVTGYGVVHFANRMLEARGESLKGKRCLVSGSGIVALNVAEKLVDLGAIPIGMSDYFGYVIEPEGFTAKNVQQLKQLKGERNARLGGYIMSSTSALYHPSEDGSIWDTPCDYAFPCAIQNDIDADAITTLIKNGCKGVFEGANMPCTDDAIALIKQHDLLFAPNKAANGASLALAATDVGHRELSPEELDAIVKDYMYQLHDRVAKTAAEFNAPGDLHVGVNIAGFLAVAQAMFRQGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS43</accession>
    <name>A0A8K1CS43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIPF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS43"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="102"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30197" checksum="0204D2CDFE93E60E" modified="2022-08-03" version="1">MTAAAMDDVKSAADALNDRGAELEFEVSVAEMEDLEDGLLSSKARDNLMGKKMGFSDRENDNARPMGMCSCFSLAFYQPYFDVDTSDVQERLVRALLPFKKSPSFNELVTKAPDAYGPVWLSTTLIFCLASCSNVASYLDFEGDRKEWSYDFSRVASACTIVEIFLVALPVLLWLVGKYVNIPMRLSSLVCLYGYSTTIFIPATFICIAPIDAVDWVVILLSMSWSLYFVLANLWTAITEHLSKEKMLPLLGFIAASHLVWAILMKLLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS57</accession>
    <name>A0A8K1CS57_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS57"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="4">
        <location>
            <begin position="673"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="942"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="884"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1077" mass="118833" checksum="61C1DC986050062A" modified="2022-08-03" version="1">MSPHFLGSMKASATSTASPPVGPTNSLNAVAASLRIRRKRNTDAAEETTTTNTTTRPPHHKGPISSPRQHMRERLWQKVGGGFGASNHDASDSDSINSPRRKLTHAMTHPPKTTMDDSSVDFPRARPIQRDLSVPTNDVLDAITLDSPPRVAVRYGDNIRLYARSKYVNSGETGGYVGTFEMPKRFLQSKNPQKKQGELACIPPIMSAGSQIYQPSMFTIHSTSRLPLGTPVSYGDVVVLVDDNGRVWNNKNGVGPTPLNGYFGPRDQNTPGEMYLSFYQLEEDGESSSSSESDDEDTFLSLSAIAKTTKTMAKNTMTMAETTFGKPTQLELDLTSAALRTMGRVVYYGDRNVIIDVADSNRLRSKFNRVVTHYRKNDELAVRGGYLRCDGKGKAILFEVHGIPLPRICSIDVSTPRQSENGEVSDEEGRDEPSLRVSMSLGAATIGHPIQLRDVLPESVVSLFFSDGGVLKVPCSRFMESNGEPFYRIVLGGSRPIRLHLRAERSYHRRSKVNLKKTLRGTYRELVKLFGVVVVICTVGAFLLNRVLHSSISLPATYIGGSTAMAVFLVEVFFPGKIIQAHVQARAEEEEDTVAFSDWKFTILSMEASESEREECAPAAMVRRDSSLMAKIPKTFIMAESGNLAKATERYEATVAWRKEMAVDTILSVPQTQYFTIKQYYRQFLHKRDKLGHPVYIQRIGAINTKALQKEGVTQDDLFRHYLFAMEFTLKYVANEICQCEACASSETQKLFIVLDARGIGMKDVSGDGADFIRKSTSIMQKHYPQRSYKIFFINVPSWFGMAWKGIKPLLNEATRAKTNILSESEAPHALLAHIDASCLPVEYGGTCECQGGCESGSDFQRTQAALVESVLNSTPFCPDDIKGAAAAPPSPTGPAELEGEVMKSRGSSTSSGYLTDGASTVYMEDDDSLRSLIPPGLFHEDVLRAGYLLKRPVKHKHFTPIWHRRFFILHPTGLRFSKTPSTEVYQIVPLTAGTVVRKNQKGNTAFELITPIMAKNGHSLVLVAPNPAVQAKWFEALQSAIAKLTPETRIPETLSDAQEEDKPKMVPTAVEAAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT28</accession>
    <name>A0A8K1CT28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prefoldin subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT28"/>
    <dbReference type="OrthoDB" id="29646at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000002">
        <property type="entry name" value="Prefoldin subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13381" checksum="D39A641A04B47A31" modified="2022-08-03" version="1">MASTQQTQQLSDQQIIAMYKSMRAEIRQMAEKIAELEVETTEHDRVIATLQGLPPTRKAFRMVGGVLVERTVQEVLPAVVTNRDGVKQVLEQLNESIKQKEASANEWQRKYNIEVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTD9</accession>
    <name>A0A8K1CTD9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Lariat debranching enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_001375</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTD9"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000035">
        <property type="entry name" value="Lariat debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="287"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="445"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW69219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="493" mass="55239" checksum="9CB4951375A9D3E5" modified="2022-08-03" version="1">MDSLVLQSTKSYGTMVRVAVVGCAHGMLDDIYATVQFINEMDPSNPVQLLLCCGDFECMRNTRDLETLACPPKYREMHSFHQYYKGEKTVPVLTIFIGGNHEASNYLHELHYGGWVAPNMFYLGQAGCVNVGGLRIAGLSGIYKHQDYTAGRYEREPYDQGTMRSTYHVRELEVFQLSHLQQREKERVQVFLSHDWPRGIEQYGDLQTLLRKKPFFRDEIQANALGSPAGELLLYQLRPAHWFAAHLHVKFAAVVRHQHTATPMEDTEETAATAGGDEAAASAAGPSPPAEPEMTKFLALDKCLPRREFLQVLEIPTTTNESTGEVEEAGQKKPLKIMFDLEWLAILRATHHLASSERYAPRVPQEDMVLEEQDIAWVRERLDEFVKDKGLDKAPGEWVSDFVKTAPGYGEEGTWTAAPTVGNPQTDLLLELLKLPHIITTPYSGAAQVPVEDPNAIDLDDEEDEEDDDAGKREETVDAQAAVADPNELDIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTI4</accession>
    <name>A0A8K1CTI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006126</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTI4"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12373">
        <property type="entry name" value="RRM_SRSF3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001074">
        <property type="entry name" value="Splicing factor, arginine/serine-rich 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="111"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="182"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="26369" checksum="2BC5909781FE3F87" modified="2022-08-03" version="1">MGTRVYIGGLPRDATSREVQDGFSRYGHIANIWIARNPPGFAFVDFEDPRDADDAIRSMDGRDFLGGRIRVELAKGGSRRDRRDDDRRGGGGRGGDRFERGGRNPPQRTEFRVRITDLPRGVDWRDVKDHLRTAGEVTFCNVENDGTAIAEFQSRDDVQNAIEKLDDKEFRGSYIRITAASSEERSRSRSPRRDRSPDRRSRSRSPERRESPRRSRSPSPGGRSPPPRKNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVD5</accession>
    <name>A0A8K1CVD5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVD5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="273" mass="31552" checksum="8B7BF626191B2E3C" modified="2022-08-03" version="1">MARRQLELRVQQMREVDQLETTLEHSLRTVRDGQTQIAEQMDAMRLLIQGMLMTESKAKDLYLDETRMEMQALRNVMQVEMESTRNDIVKLLETAKQNVTATRAEYDNTRAEAAQKLKELKARRKEREQQHMMEIAQIKQDAAMQIAQLQEDIQMEAERVRQLVEQSALDHANVTQESLGETELLTPSTQTPSWVVLVFAALCIVALLGWLYSRQLGRKHQRVLYSKQLKSHFSSDEPTATQDVRPTLLRHTRQSHPASSTSSFPEARRSHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVH2</accession>
    <name>A0A8K1CVH2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVH2"/>
    <dbReference type="OrthoDB" id="63936at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="113" mass="12350" checksum="EB41D3D77347F710" modified="2022-08-03" version="1">MVRVSTNKFLSEVSALYDAPVAAGRKGTVAISCKSVPGAKVFKESEFDHVLLFRAAKYGNNHHKSKFSAIVTPREHARFHSQLSHIIRTKADSKTRGGVAMIGQRGKGKKANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVI0</accession>
    <name>A0A8K1CVI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVI0"/>
    <dbReference type="OrthoDB" id="69430at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="103" mass="11871" checksum="7DEB583B9A06FE12" modified="2022-08-03" version="1">MAESATTYCLYPSKPCFNPRAVKVGGKPHKLCEEHRRKANENQQRCLYRKRLRELEAMQERMDEEFDNAQRLIDETMIAVGALGDDDDLTEEDLAILVALLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9M1</accession>
    <name>A0A8K1F9M1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9M1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="23"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="35193" checksum="3A7631FBEA55C7FA" modified="2022-08-03" version="1">MTLPSTFRGYVYESFGDYQEVIKFRSDLTHKPLASNQVRVRVHSAALNPGEYKVIEYGARMLPTPPTPEEPFGIGFDFAGTLVEVGQDVNDLTVGDEVYGMVDLDMGSFAEYLVVGAESVAFKPHKVSFDHAAGVPIAGLTSYQAFTKHARFQSGQRVLILAGSSATGLFGIQMAKVLGASFAAVTASARNHELVKSYGADLAIDYTTEKWADVLEPNSIDFIYSCGVEPNAWNENAKRVLKKNTGVFVTIDLADPPLVSPVGATFILMRAVGSKADLTSLAELMDAGKIVTPIDSVHPFENLLEAVKKLKSNRARGKIILQIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAL0</accession>
    <name>A0A8K1FAL0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="644"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="7">
        <location>
            <begin position="1039"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="804"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="807"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1337" mass="150407" checksum="2863CFA787CAE2DC" modified="2022-08-03" version="1">MEEVFASLDTNMTLLERLDDSSQQDPTRIREPPEFLCALHQQYDSILHELDAFQVVGNQLLSDRVLHRQLCLKSSDHDDGEPSSISACPWRYQRENLIFLQRHERRHRPLAIKRQDRGTSESVVTRDTLASTFSPQLAGYQELQWYLASATLAANESDDNESDDEDDKADQKARSETEVVAVMSYRRRQAPSDAVTAVESLIAAHQELLLSPYFQQYLGCHEAAERDDPNEERTEQLYCFEFAPTLTLEQLLRIHGGFHEKSKAFRFFAREILLAIVDLQEQSTHTLHARLTPSNVLISYSGRRVLLGRLEFGESIDFFKTDITIVRCRRENERLADLALLLFALRYGLTLPLNLSAFRSQYLACHDPQFVFEFALARTSQPCSIHVGVGSTFTLLLQEDDQAEWELVSVERLELVAEDMASMMSAHVTPPPAPVAPASSSHVATATDGVGQASSSATATLDEIFLADGHVNMRLLMLSLWKYRKDEEFTRELCRRLGKLSLSTTTLDQAEFYLPQLAHMVIHLDKELPIEDMEQFVLLLSQSSVHFALQLFWIVYAALDEHRPKLNGNPRTFSRCTKLLLVLEQCLVYGSPVAREANELLLRNNISKAEMEQIMLADRRFFAAQSAMDKGDVALDASVAANTGGPAEGWLYKKGGGTSKMGRRNWKLRWCRIERRMLLVFSRPTDTFPRTAVALDRAELHVVQNPKHPFYFELEHEFSETKMKFAAQSQEDLVNWIQRLHRAACAPEPPVAASPRSTSPTKTIARMSWAMRSLVLDSANAPVDGETSPDNSPMKADAIAAATTTTSVGSPSKSASALVSPPQSPKCRNLSSPFGTSDAWSESLRRARTVSSVSAVSGHSTSSERSMAVSDSDFEFQPSLPYDQQRRYEFFTGMITFVKAITDISEALRRVEPPKRKASLRPHLELLHIPQNAYIPLCKSTDPYCRVVSIFASEGRVFSTHERAPCLLYFDTEENEQGRDVSHALFDLFFSGEDSDSAANDPVPTQSKVPVNTNAIPSDASPFLRSLLSSSERNKRLEKTFGELSYSTSARLREFSLSPHPNRWRLCSLIAKSHDDLRQEVLVMQLISFFDHIFRLEQLPLRLRPYRILSTGASTGLLEVVRDAISLDGIKKTPDFKNLRHLFEDLYGGTVDGEEAGAGDELLRQAELNFIYSLAAYSIVCYILSIKDRHNGNILLDVEGHLVHIDFGFFLGRAPGGSFSFETAPFKLTTEMVDVLGGRQSTQFKYFSGLCVKGALAARKHAETIYSLVEVMSFHSKLPCFLTNTAAALAALRERLFLNMPEERVEPTILSMIERAYDHFGTNKYDQFQVYTNGIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBE0</accession>
    <name>A0A8K1FBE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBE0"/>
    <dbReference type="OrthoDB" id="45220at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="405"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="540"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="600"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="580"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="687" mass="76871" checksum="F8D4DB094C8F5E1B" modified="2022-08-03" version="1">MVAKKSDVAASPDGLSMGNEHTTVDAVVWTSGPHDGTSVWGQLANGPSRISAMIERKQARELMAGEHDAAVPRSSHYHARESTHAPRYSTKEQPQDDDDYGRRTSQYKPVHRLAEMGEWSTLLERIECDPTAAQHKDQHGMLPLHWACTENDVPPHVVKRLLQAFPEAVLTRNNAQYLPIHIAVRSNACEETLRLLCDARPSSLLEETPSGKTPVMLALECNLPASTVEILRIAEQTYLDLIEENDSQDMEDTKRNIEVQSHLLRESMMYANNAHMNRMSETADPNEQPNLVGFSWQGPPRSKSHPLQQSNSMPRSQGRRNSAAIVRYNDSLMMHDTRSTVIDEEAEGYNSEDGSSRGGPDMRSTYSMVPHRQQQQQMYGQGGYGHLQQHQQQFAHRATEGDVMHYNSGVCGICYKKFSMFRKKHQCKGCGIYLCRKHVAGKIEFPDQVKKRSACADCYITHRHGPSLMPTVPSQSMGANYSFMHSGPVTSNAIVPANRANRTGSTPAMFMARKSTMRNSHLSTASTVSDMRHSMLNPSTRSSLRFGPLPPPNQRQQSQTMMVPMPMPKPPMHPLDRYGSSDTATTTSLSDSTDRNSAEVTALNHRVATLEEQNKVLLSRLADQEKQYDEAMLLLTQTMTRVADIEMRMTGMHMGQYGSEMDETDSELNPASYDYDYSMASMAAYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC43</accession>
    <name>A0A8K1FC43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006801</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC43"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="30470" checksum="55A8FC76A42F7DC1" modified="2022-08-03" version="1">MTADVNAAAAACPHAAGANKPKKANGEDKSCGFGSQMMDIARHAANGGSWEVTGSDVDLPRLSKDREVSSIPKSDFTPAHQTGSQNKWEYPSEEMYYKAMQRKGWDPEASQMKTIVAIHNSVNEQSWREVRKWESFHPASEEPKLKRFIGRPTDFSPKARLMNMLGWSVLPFDRHDWIVERDGKEVRYVIDFYSGQPEPGKPLSVYLDVRPALDSVESVMDRVRWQFYEKVVPLLPFRGALFGQEQSAKPKADDSNATHGRSTVIPRNSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC48</accession>
    <name>A0A8K1FC48_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC48"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="38988" checksum="0494C93DD6661128" modified="2022-08-03" version="1">MQSPSASPVSRLLRQATKTFSRRPTPLEREQQALEAKDMSSPTQVDEDVGKAAVVDAEPHTVDDFEEPLDNQERPLIQLRSVGHVSLEGSTGHANEDRFVIKSNDHFHMFAVMDGHGGDMAANFLVDKLFATLETVYQSHNGFDHAALTAAIEDLDRVFLNKARRLHDYSGACLLIVLLYYDAAEECYQELVLNTGDCRAIVREAPERRSLSGRKLRDDTSDTTVVALSEDHCAKNRAERIRALEAGAYIQNGRIAGILEPFRSIGDLDMKSKGMEGWVIPTPEIRQRDLQIGQSTFVLATDGVWSVMSSRRAIAIAHQELTEDGDAQSAAEAIAEEAVELGSLDDVTVLVVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD95</accession>
    <name>A0A8K1FD95_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD95"/>
    <dbReference type="OrthoDB" id="67991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="22829" checksum="5E7A4000E46049E0" modified="2022-08-03" version="1">MSTLRSLVFVEALDIDKPRLLRPILIERVESSLKQNQFFLFSTPTYVGKTSLFQLFNWDCVKLSWVGVSLRARRVPPIYALLNAGIDFKKKDFSRLRAGRAYLFFLDSAEMYYGDKEFWKTLITDAPSWLPLNYRFIISATDGFYTEEPAEFQTLPRFGMRDFLVNAEESRILLTLPKTGLPTPLRYYNRLLSVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDB6</accession>
    <name>A0A8K1FDB6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006724</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDB6"/>
    <dbReference type="OrthoDB" id="2020972at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18007">
        <property type="entry name" value="DEXHc_ATRX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="141"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="580"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="616"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="782"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="659"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="791"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="868" mass="96389" checksum="B7FCC934C6F6A671" modified="2022-08-03" version="1">MTCSCGLLPCICVGSFEESADYELPVTSAASRLRSLVAENATTQCMSCMFLPCICPAEDEDEEYGADEATSVEATSPIGSEIERRDTDASSQEEDDDGAERDDFDRVRLPPANGNDSDVWIAREIKRHLRPHQVEGVRFMYENASANQGCILADYMGLGKTLQVITVIYSFMTDRLQQIEGKDGEEHALPSTMVLCPAICIPNWENEFKKWLKKDSLEHCPIFAFDATAGKGSVSSRIRLLQKWKHQGGVLLMGYEMYRSLLNPTVTASLDRDANIQICTRVGTSTMEITNSVSAKVQKTSREFCHLLCQPGADLVVLDEGHRLKDPASLLCQSVAKIESKRRLVLTGYPVQNSLSEYWCMVNFARDNFLGSYDAFRAHYERPIMEGHAERSKELISKLKEVVLRRGQALLKTQLPPKREWILYCKLAPIQHQLYCDFLNFYGETNTGRATADLLTAYAALLQVMNHPDIIHTKVLPGEDSNEDEAEASPSIADEGNGWGWESEDKLLERRQQAAEQLRKRRQKITDRQKSYEWARRTVLGTDRSVSRRRKQPGQDVVEDPAAYQTMILENSGKMAVLMGIIEESFALDDKVVVFSQSVPTLKVISDFLLASHLNPNHGGGAGASGTKSKEVPKTKRRKTADRAPKRDPAGLLRKKSAIKSTGKSGGSASDTPVTDQWFLQIDGSTTGAKRMEYIQAFSAPDNKVKLLLISTRAGAEGINLHAANRLVLFDVSWNPSNDHQSMCRSHRIGQAKTVHVYRLVSTGTMERMIYEQQMKKVDLSTSVVDDKSSRTGGQSTSLPTDTNSGAVVPFSGFLQPPEACDFNQVVHVDASILDGDEVLTKCVTKSGHWLVDVQPAHDDEEADDEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDC6</accession>
    <name>A0A8K1FDC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA-processing protein EBP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDC6"/>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39749" checksum="C15D525360F1267B" modified="2022-08-03" version="1">MVRKSGRKSAALVSTLVRMEDAAEEEILETPAVSSLGNVANVESGSESEEEEDEEAELERRLVEEQLREEEIARNERENKGIYNGEALKQIVADWDKEKQLHWVETLDTCVAPLELTNVHDDLKREVAFYNNSLASVRLAKDRLKKLGVAYKRPEDYFAEMLKSDAHMAKVKDKLIYEQKKIHAVEERKKSQAHRKVAKEIQAEKTKQRLQEKKDTLDAVKQWKKRRNQDKGGAIHDDDDNELDAIVSGKATPTATGKRKRGADSNDANKKPRVNKKRESKDKKYGFGGKKRYAKSNTRESTNDMSQFRKQRPGSGGKPGGKPGGKTAGKAPKPKRAGKTQRSKQRTNNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE23</accession>
    <name>A0A8K1FE23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE23"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="65428" checksum="824CECC21BD1A45C" modified="2022-08-03" version="1">MQESGNVSTLDSYVDDYNSYSACVMSAFGTPIEALVNTVVFVVALRFSTNLVLHPATSWRFGAFLYASFLALKYLVLNGMNALNVQPSQSHIQPVISDSDLSVVSAGGDSNIIGNVTTSLHSFSERAPKNPISNTVLRNVILPKVMKPGERNGQCSRGDVLQGDDKLIHGFPTRTWQRNMLSSAVEPDILRIPISKDTIIDADLAKRLPMNASRAANLFATGVWLADMFAPWFKVYRTVESITRLAEGENSILSLAQIDRLLPDETVDEEAQRLWFLEKSQGEMTNSLSNKWSTFTKATEKPLALEFAHVNLFSSFRSANALWLTRAAELGCDGLHYELEDGQILIEGGNALPLEVLPTPRGIGKSGGYMKLVDVTEPPAHPEAIPYQVTSPDDASDILLPHNINSTHWNSEHVLKGQRCRTWVENRIQNVLNNHYYIEDPLQPSYTAAMFFLFQNAVAKEAILLPDNHKSLKFDNNQKILVLQLRIPTQNMMMTHCGCGLLAVGALAVSFASWMLTGGSNPRSDPLLIISSPHVIAQVKLDESKFPPLLFRRRLVDSLDGKDAIIGDVDAFVIRGLSLEHQGNDEEKIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE51</accession>
    <name>A0A8K1FE51_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE51"/>
    <dbReference type="OrthoDB" id="163959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461821" evidence="1">
        <location>
            <begin position="22"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="24355" checksum="6B335F6CA3CC80E7" modified="2022-08-03" version="1">MIKSLASLAVALAALHHGISAQETSSFCPPNMSEMSVEGINGVFCVIKGHECVANIKGDCPTKQLGLDYGSYCGTVASGVFGCKVLTAESIPTYQPTFAPSKRCADSEVEVSVEGVQNSYCVDASYVCTAARDDGNCPGPQPGLPDGSFCDIVASGVYGCKAFNGTEPTEYEPEAPRNCTGSIYGDEPVSVEGVGTFCASGDICSGDRYGSCPAAQDGLDADSRCVIVSTGVFGCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFZ4</accession>
    <name>A0A8K1FFZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003223</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFZ4"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477510" description="hydroxyacylglutathione hydrolase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="11">
        <location>
            <begin position="66"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="35027" checksum="F044D395C5AAF987" modified="2022-08-03" version="1">MTMRLMGMRGLSLLPHSALASSLRTQTRCSFVTLKGGNAASEDKPKSKKYLRDPSLRVRIVSMFEDNYGYIVVDEANQTMFAIDPAEPAKILPVLKEEETNQKREFLGILTTHKHWDHAGGNQGIADKYPKALVAGPAKEEIPARNKALQGGEKFKVGASKVKVLSVPCHTAGHLAYVVTGDPDTPPLLFPGDTLFIGGCGRFFEGTAEDMYRALYEVILTLPKDTRVYCGHEYTMSNLRFALSVDPSNAVLREKIAQVKIRRSKNLPSVPSTLREEMQYNPFLRVHEEVIRNAVGGSDPVSVLDHLRRQKDSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGJ7</accession>
    <name>A0A8K1FGJ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGJ7"/>
    <dbReference type="OrthoDB" id="10606374at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474007" evidence="2">
        <location>
            <begin position="30"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="33109" checksum="B693D4A51A5628A9" modified="2022-08-03" version="1">MVFSTRSLFSASGLVALLALAQQPAHVDAHGHLIEPKADFGANKKMMSSFAGRIPEPNVIFEGSSFPESGTRQNYKEFMKYYKAGALRDIIKKNNKPLDGATADCGFSVVGAAQKLPSTVLWGKNEGTADSEGFRPSHLGACESYCDDQLVQQADECAVAYNVPDNKGSAQMKLTNPEKCTGAKQFTFYWLTTQARDEGGFQVYVNCIGLDGSGASAGGAPSNSTTTVAPTKVPAGSDADDETPGSVAPSPATDDDEYDNETTAPVAPSNGTDTTKTKKPKKTKAPKTKKPKKTKAPKASSDDSVGGDADDGVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGV0</accession>
    <name>A0A8K1FGV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGV0"/>
    <dbReference type="OrthoDB" id="432686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="28942" checksum="C7E541D0CF5B819A" modified="2022-08-03" version="1">MGRQAHSSFNAKNETVAPSALGITEGHLRNIKGEAVAYEVPRALETHEIPAIVEDYRKSAELAKQVGFDGAEIHAANDYLVDLFLQSSTNKRADKYGGSVENRTRFLLEIIDAIKTVWPSDRICVRLSPNGAFAQMGGEDNVETFTYVFQQLNKLNLGYVALLDGFGFGYHGKCRVVKVFDAKTHFKGNVIATNSYACDTAEGVVRSGAADAVGFGRLYISNPDLAERFQNGWPLNPDAANEDYWDSSKGAQGYTTFPAYTPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH17</accession>
    <name>A0A8K1FH17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable threonine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_011906</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000019">
        <property type="entry name" value="Threonine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="898"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1294" mass="146199" checksum="2392E86E12B6E4FD" modified="2022-08-03" version="1">MELLVWHDALGSDDEQATEEELLMRVLYAYDSAEALDEEDTTTRAKRLQTLHFVQGLANFSRLLRRVSTATGEQKQWSSIVLSKRRFFIQQVEPQVFMALGVLPSPEDSTELKSAQGAVLQTAYDLFRLFHGPVNQQLRDLDPTVSKDPTWTDGMALLGHLQTLRKQLRKANLAIEMHSHDNTDEETPSASSDELKRLGKEVETLKSELLELEPHSPATRVRQHCHAFFPKLLRCMDAQLVNTFHCLYGLSTASPSDSTTALSLQSAIHTLRQELVSDVSHVALFYRGQLHWSSLENTTLAPLTRFLQYREQDGMDDITWTEQDESPSTLWMRAKSHDAFLPVWASKTSYAECAVVTHVAPQPRRAQRRSMHKLIPATSLNALVSDVQHAESAGKGKSNGETVDVVARLRTQRYRPNGACYRNCGFLTEEGAFASSWELNDGAHDAIWAPLVHIRTSDKDGDDSRHRCQVWHEADVTLILLSTSPTEVSTAVLERIEQSIERVQLVQLMESLTPRATSVTSSSIRAGCHPSASTVWTAHPLALPSLLDRHPSKETMDATRVKTRLTQASGPTIDPQDQKIGGEFTLTPNPPFLAKRVEVYDRIMAKQRAEIEALAAKNTAIKIELPDGTIKEGVAWKTTPLDVALSIAQGLADAVVVANVTYRGHVEDPFSVSAADVDGNETRDADDGGCCAGASHAELWDVFRPLIGDCKLQLLKFDDKEGRMVFWHSSAHILGESLENLKGCHLTIGPPVEGGFYYDSYMGKETVPESDLSVIEKECLKVVKDKQKFERIVLTKDEALEMFADNPFKTQIISTKIPDGGKTTAYRCGPLIDLCRGPHVPHTGKIKAFAVTRTSSTYWLGKTTNDSLQRVYGISFPDKNQMKEWKHFQEEAAKRDHRRLGLSEELFFFHQLSPGSGFWLPHGAAIYFKLLKFIRSQYRERGYTEVITPNVFNMELWNISGHAMHYKENMFVFDVEGQEFALKPMNCPSHCLMFDHRSRSYRELPIRYADCGVLHRNELSGALTGLTRVRRFQQDDAHIFCRDDQIKSEVISFLTFMKHVYDVFGISFQLTLSTRPAKAMGEIEQWNLAESQLSEALDEFVGKGNWRENPGDGAFYGPKIDILITDALKRQHQCATVQLDFQLPIRFNLKYRSDDEEMFKRPVIVHRAIYGSFERFIAILVEHYAGKFPFWLSPRQILLVTVAPTFTDYAYQVKDELFRAGFDVEIDDSGKTLNKKIREGQLAHFNFILVVGAQEQENHSVNIRTRDNKVHGTKTVAEAIEMFKKLEETKSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHJ1</accession>
    <name>A0A8K1FHJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHJ1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="210" mass="23706" checksum="BFFF18B516250BF3" modified="2022-08-03" version="1">MTNSERARYYRERNAATRAETEAAVEELQRAVDSLEIQEEMYRQLVHLDVPPTTRANIVRLLVDFITDRLDTLLLTLQNSSHELERVEVTGDALAPIVRIDCSLRGHLTPSTTHQIYPHVIGNSVLLDRMMHDQVDLTCSCWFYFTPDGTLEHHTVEVNAVNGLRVLLGDLHTVGRVLSNVRIDRVTVYPNGEEIGRHASALSLAALDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI29</accession>
    <name>A0A8K1FI29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pre-mRNA-splicing factor SPF27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011425</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPF27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI29"/>
    <dbReference type="OrthoDB" id="205794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008409">
        <property type="entry name" value="SPF27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13296">
        <property type="entry name" value="BCAS2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13296:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SPF27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05700">
        <property type="entry name" value="BCAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="25058" checksum="3A8B5DD16FAC92C9" modified="2022-08-03" version="1">MTSSTSCPLLLESQALIDTLGYIDTEYNDPTAQQVVQHLIRAEMTKFAPSPAYLEFLPDYTPTFGDNARLQSEFRRVKANVPLNAIDLNRYQVKEPSGKQAEDVETWESAVRRLKIHVEHQNDRVMNLELQHAYGTKMWKIRAAMLEGVNAQYDKALCDTKAASESVNVKRKQEQMLNAPKLQTYQHKFNDLLDKNETIQRACVAEERRKKAKTEPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIC2</accession>
    <name>A0A8K1FIC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="148"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="369"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="412"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="858"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="943"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="648"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="715"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1312"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1442"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="733"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1312"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1328"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1445"/>
            <end position="1460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1472" mass="161288" checksum="DC81A3D2BE6438FE" modified="2022-08-03" version="1">MSNRGKRRSATVFSRDEIGVEQLQSLKEKFADGDLNEKEFVSLFREIIDASLSETQLTELFQKIDANSDGTVDWDELTNYMFLSGSDNSSEFIGDDGNAFYETYQPDKLGELPSSDANGGGGASVSGLSGAAAVGSGQAGEGSAMRPMYHHKDLITRVIRLDKPYLYLTASKDGSVRTWNANTMQFQSIVTTGKNWLTDCCVMRRSNRLAVASMNRTLGFYDLNSNALIGEITEYSKRQCIPLCLEYVEKPADDREALVVGDDTGGITVMTCSDQWIACDGRSNGGTTAASSVGAGSSITSSTLNNPTNAAGSASLEAQGFLSRTKFKKHRDWVTRVKWVNDIRAIVATSLDTNISIIDVDRMTVKFEYNRHKKGVFDLVWCSSTRLIASCGMERDISIWNPYSSQRAVATLRGHTSSVLHLVSDDDNYQIISVASDNTFKVWDVRNHRCLQTWVDRYKSTGGAENRISSLLFDPKQPCLVSGTTHLTRWPFKLQHDDEQEDEEIERPMCIATYNAVFHQVVTAEMSAESVVKTWSAETGDEICSFSNAHGQSPVTAISFDYPGRRLLTGSHDGTLLKMWNFSNGALVKQFLKQEETPNTASTGERTSTLVAATASSRASASVLPKASSSATATLTLSDDLSFLGLGGSGNDKNSDEEDEDVRSSAPNGLKKTPATQSVSSMTSTSPRKRKVRDIMLLPPTFGIDWEGRKNANLAGYSELPSPTRARLNSKAGNDRERLYPRETFRPNPPDGGSDGSKGSEPTPPSTDAPGDSERTPRSRNSMSNTNLLRTLCEKEVTSILDIERNLRVGMGDYICQRFVCSVGWDRNLFIWADKNDESEALPVHVLPNPKTAVSQPGKCHTMDILALVYIPPAYIATAGLDGKILLWSINSGEFLSKVYQSQGSIDTMWYAQKIEMLFASGETGQLVCIDRSMTPRAVIPLEHPNNEAVTALKLDRTNTHLVTGDITGHIKLWDLAIAAEHDGLVLEICAMWRLGPGRVLGVDFVEHVRVNEPYLLLSCANGDVSMWTLDGIHIGCFGKHRIWQLGRPATYQASESSCMWPPRPTAEPGRLVTAEILPVKHSVKCFSIAALNGYETARETFLLEDSMPKPGEVWVCVSGHRARTNLANAKKQEIAAAAAPPGSAGGESSIPSGAVPAMFRRSSNNNASFILRRTPSSREKETLASMSVLQQRLSELAGDVIDIITVVKVTRGEISCWDGNGHKPPLLKVIEMSDFVRKVGWIKQPLLTQYIGRLFVDDLSHFRVSGISLAPTDEKSDRKVFWMVDTHGQDHPMRPLNEAISMARLKLHSSAPTTPLMSQSSARKQSKPSLLTKSSTTTPGIKGTDGRIGSTSIAVDGNDALADDEGGDEVPDANETKFLHALPLIKPKEKRVMGGLLPKRSSVRMRHDQSVDFRRVHAPEDIPKNFRVALQNRLQSVGNQLMQSSASSNNNKDNSSRSSRGASRFDGIIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIX9</accession>
    <name>A0A8K1FIX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate-binding protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIX9"/>
    <dbReference type="OrthoDB" id="167542at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796">
        <property type="entry name" value="URG4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate-binding protein N-terminal" evidence="1">
        <location>
            <begin position="343"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="66711" checksum="AE28EECE0C40C963" modified="2022-08-03" version="1">MIVFVDAKGSASLYRFNEHYKALEVVRTIDIGAKTSLVMPLKTVLLDDGVMHVVGAKGNVQSINVRNQQLSRKSAKCCFGVEGVTWRGPLFAILDGLVLGSVGCMQDDSGSYRGVVEAISSEDYRALRQRSRDGIVLGSSEKLSVQAFGNEVVVFDEESTKLHVLTLQASVRSDSLRIRKMNSGIDENECPGAAVGSSSFSSHWMWVFYRLFEKFPVRGALYSSERGAPEQLQLQINGRAESQDMDELSGAVAGYLDRIMDELEKLHKPLYGLNLAQNHHSLVTFVPIQICRAEYNTLSVMPNGGDRSEDIAGSSPKDLQSADIVRSIRFGLLSPLLQSWGGQCVVVTSMGKQSTGKSYFLNHLTGSSFAIAGARCTDGAWMSVRVLDCHVLLVVIDFEGLGSFERTEQEDVFLSVLNASISMLTVFRMEMRLDKEIDDLFSKFQKGSQQLIKNESQLFRGKLYMSVKDVNPNDHRGVVHEFVTKFGRLLDANRENNFLTDMYAGQLEVNCSPPLSTPGYHRSLTHVQRSIREKLCGNPKAGFSTGKSFLDCIRLVLAKISILDWTSMDDSALKLKLAEMATQLPGIVRFGAIVASPIRLPTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ45</accession>
    <name>A0A8K1FJ45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ45"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000026">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="40778" checksum="DA774E864E19B369" modified="2022-08-03" version="1">MSVIIKKVTDFYKKDECSKYYKLGKTLGTGSFATVKSAVSKADGSRWAVKCIDKASLTAEDEEALRVEVEVLQLVKHPNIVQLKEVFDCQKTFYMVMEEMSGGELFDRIVEKEKYSEKEASSVVKKLAQALLYCHDKGIAHRDLKPENLLYQSTDENAEIKIADFGLAKLVKGDSLMQTACGTPGYVAPEILEGKPYGPEVDLWSLGVIAYILLCGFPPFYDENNAALFASIKSGIFDFPSPYWDCVSGSAKDLISRLLVVDPKKRYTAQHVLQHPWIEEIQNVSDEALPHFTAEMKRYNARRRFRAGIMAAKAISGLAVHSVKKKSNVAQLDSIVKEAEEVLAASPVTAAAPTTTTPASTVPAPVPATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJN2</accession>
    <name>A0A8K1FJN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI inositol-deacylase</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004005</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJN2"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482472" description="GPI inositol-deacylase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="615"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="794"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="13">
        <location>
            <begin position="73"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="848"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="881"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW66240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="930" mass="104555" checksum="EB52A23BE226BE98" modified="2022-08-03" version="1">MPMTRTWLLPLLAALSLVLSAVYVADLLKTSAHASGCEMTYSWPVYTPVATKALRHHKFALYTIHIQRRREALTGVPVLFLPGHMGSYKQGRSITKHLTDLDAELFDVFAIDFQEQLTALNGRFVEDQAVYVNDAIRAILKMYQKQKNTGGKKRRVPESVIVVAHSMGGVVARLAETLPNHKRQSIQHVVSLGTPYDKPPLPFDADAQSVYSRIHAKIAKAAGSSSSSVASRAALTTGSSSPSSTVYVSISGGHKDTTVHSSLSITARIAEEEYGLALLSSTMPKVGVTMDHLCLLWCHQLLRSVAHSLVAVVDKDKRELIKSPSRRLELAQLHLLGVKNEDLNQTATLIQYHHDGLVDGYHSVDEFASYKTYMPRYFVRLVRARFTTLFWVMYLLVLHIFHLQVTRWQQRFDLLAQSKATPGVSQEAFPSFTSMLHPVEHAPKFIKSLGAEIARVLETQPAGRRKTIVAGLFTGLVILLGIVTELSRRYTNVFVLTTEILQLTVFYVNALGLLYVFAMLLSLVRMLLHPLVRVAVSIVRRMRLHRWIVIAIVYVLVVLIGHVRDFDLLPLDSTPRHLALLVLGSAVIFMLHLLELGVKQVEVSTDQQRYRSTLFAFYLVSCISWIGPIAYFVDVVRDPPPQVSNDLLVNVASSVSILALFRYVITRTESEMIPLPPTAFFDAEESDVYGAEEGVKTTAENCPRCIYEDGGPGAVFIEYESRANTRRIKTKQNEIVVVGPTFRVVSCDCVFRFKQPREFCGFCLRSCRLCGGGSGNFQEAQRYQEYLDRNKMDVAMHSVLASSLEWTVLVLLFLQNEHYLYYVTPSVSLLLAVYHSWMRHPIEAKRIKKEQRKKQNKLDAAAKKKKRASYKKKKSSQRENPQPKRESLQPKRDSLQPKRSTTTTKTTKQKSFMDDYAATAGPTQGIAGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJR8</accession>
    <name>A0A8K1FJR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJR8"/>
    <dbReference type="OrthoDB" id="118200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="139" mass="15590" checksum="3C12113CFE4A0C5D" modified="2022-08-03" version="1">MLPSNRALSESSEVSVNSLTFNLTKAQEHFDEHKFADLGGTCTFYSEIGSSGCYKPRSCSDCLVRSECMINEFGVCVNREFGGYNESMDFRLAQKQGLVMPPTEPSIVNTAQSWHFLESAVDYCWEADPVCKQCREANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJW9</accession>
    <name>A0A8K1FJW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013616</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJW9"/>
    <dbReference type="OrthoDB" id="62564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF193">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425411" description="FAD-binding FR-type domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="47254" checksum="F8EDEA8B0CCA80F0" modified="2022-08-03" version="1">MIFAVMHSAPLIWSVLPPVLLYVVSRAISSASAFAPVQVKELIALDNDIVKITLHRSTQRDGHFHVGQFLYINVPALSKLQWHAFTIASSPHASPTTLTLYIKSLGDWTQDLVTYANDCKQQHVLPTVYVDGYYGSSLGVYEEYSTLCLIGGGIGATPMFAILEDVVSKLSSGSSLHQRVVFVFSFRELSLLEELHPLLLRVKELDPDEQHFKLHFYLTRSMDEDTLTHKIDYSRLAGEDVAASSSSTSTSLPVYSPLRQRGFITIASLITFFVGILLVVYLEYGTLGGKIRRNGRKYLWPLQQFVEIAMVFVVGVVVFGFVWAERLHKRRQGKLESEKEPWTPSFPLSTDVVTYADLLSHYSVTMGSRPDVKTHLRAAMNADPNPAAPNGVFVSGPESLKTATDHAVATLGASRFDCHEEAFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE0</accession>
    <name>A0A8K1FKE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE0"/>
    <dbReference type="OrthoDB" id="194079at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44616" checksum="909A061C1A9E0421" modified="2022-08-03" version="1">MRSSTATDTPEVDEFGLLSKAPREDEANVRANRVEISWTTPPMEGQPPSARGGHSAVLVDTQLLIFGGHFFGGHGSFVYLNDLHRLDLETSTWHEIPFKERDVVVPRPRYNHSALLMNGNTRMFVFGGRGENAQVIRDMFFLDLDQVAWFQVQWTTDCPLGRFGHGCASVDDQNMLFFGGWDGKKSMNDLWSFDTNTFTWHKPKCTGKPPTPRQDHSMLPIATDLVMVYGGYTVLPEALPAYNKDIFLLDTETLSWSRPRLTGEYPLGTFGQTVCLQNELALLLGGWSGTERTPLYMGDKQVKELVNMLAREDRLVSGQETRSSRKENTKKLKSSSSYTRVLDVTRMQWYPVVSHGVVVSNRYGHTCTIVGPHLFIFGGWDGNRALNQLVVGEVSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLU9</accession>
    <name>A0A8K1FLU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012824</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLU9"/>
    <dbReference type="OrthoDB" id="150687at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074:SF9">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19859" checksum="F1BB6454BB9D6B63" modified="2022-08-03" version="1">MQYGGGGGDVDRALSSIRARADHLRHTIARLEHNLAWQPASTWPELLSQFMVISKQMENMNEEIPDMIQHFACVPRMATPNPADIPLLLSTREDTEMENADRELMADKPREKSVEALMQVRNAHNEAVESLEETFREMSDGLLKSIRVNKYVTKTKPQSTQSHQFKFIESGSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM02</accession>
    <name>A0A8K1FM02_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM02"/>
    <dbReference type="OrthoDB" id="164238at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="699" mass="73527" checksum="D0C0836732653B16" modified="2022-08-03" version="1">MNGAQGLVLTGPSPSTPSASTAAVPTTPAPPYWSAFDQELIETVLFTAGVTDHEASPSTTLSMSDTATVASDFGQMSPVSTTSSGAVMMSPTEGMPGLSLGDVYSSDLVGVSDSDTSSQTKKPKRKRNYTDSTRAKHREVQRRFIVRKKEKMQQDKQLAVVMEKQVQFLNAHAETANLERERTSLLQQCVAAGVELDPKDMDIFLKEETEVLTHYFTPLAPEEWQEIVNQTLRYIDGFHPENAFLDAGMNIGGWTQESRIALDTISFRMTKSFHGCSCPTVFDRAWHAVRSTSLYEDIFNSGIVIHCRVLQVINDNTVIFYRAFYNSLTKEITRSVELLCAVQRDNENLILMQSLEGLSIQSVVGTAESWQRGVNWCQITPLSAEDEKNASGEGCTVRFTGCVGQGLESLMMWCREIVFLMLRFENVVLAPLFAPPGTEVAPLSLESLISTFAGSADPAALATAAAAMGAGVPGLKTTEGSEVSEKKATPLDSVLSSLTGGDPNALAAAAAAMGGALPGLNLASDAKTPLLSSLISSFTAGDPATLAAAAAALPGLKLGQDAEGKSSLGSLISGLMSGDDSALASAAAAMGGAFPGLKMPEVEPEAEKPPVLGSLISGLAMGDPASLAAAAAALGGSFSSMLAKAEEKGEAKAPVEAKSEENKEEQVQSAMPAHAQTKTPNAPQSVDVSKSSNPAADLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM17</accession>
    <name>A0A8K1FM17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">pectin lyase</fullName>
            <ecNumber evidence="6">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002179</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM17"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047490">
        <property type="term" value="F:pectin lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF67">
        <property type="entry name" value="PECTIN LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423667" description="pectin lyase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="8">
        <location>
            <begin position="94"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="40798" checksum="59B4D4E7016F6458" modified="2022-08-03" version="1">MKIFRAVVIAIVSFTASVQAAVPGAAAGTTGGGNATPVYPTTIAQLKTYLSDSQARVIVLNKNFDFRGSEGTTTERACRPKFALDCIAKNNGYKSQDMLLSVSTSCDGQYVDGIKYDNAGAKGGLVVGSNKTLRGEGRSGVIIGKGLSFQGTNVIVQNIHITELNPHVVWGGDALGFPGLGDTPASKVWIDHVKVSRVGRQMVVTNFAGVNGLTITNSDFDGRTTYSASCDGHHYWGFLLYGKNTRISMYNNVILAMSGRSPKFGGSSDSNVVAHVANNFIWDNTGHSFDVGINSAVIVEGNYFKGITKPITAPIEGSLLMSTANNIGSCAAVLGRNCVANVLETSGTLTSNKDSDALSKVKTLATTFKPATAKGLTYSAKNWGVGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM56</accession>
    <name>A0A8K1FM56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007548</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM56"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="287" mass="30737" checksum="6FEF81F71A5CB453" modified="2022-08-03" version="1">MASTTNNKVWLITGCSSGFGRELAIAARNRGDLVIATARKIETLRALQDLGCEALTLDVTADDATVNDVVVKAHGTYGRIDILVNNAGYTSNGAVEEASNEEIRAIFETNVFGLLRVTRAVLPFMREKRSGIIANIGSVSGYATFPACGIYCATKFAVAGVTQTLRQEVAGLGIEVTVIEPGMFQTNVLNAGTFFKKSIPDYAPVTQFFKDIAEHGLSVPASNPTKGAQAIVEALTKSGRCEGRTLPGRMPLGGDVFDAIQNVLTTGQKELDEWKDFTDSNAFRFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMW5</accession>
    <name>A0A8K1FMW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMW5"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009069">
        <property type="term" value="P:serine family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="34235" checksum="73852E2E72975788" modified="2022-08-03" version="1">MNPCGSVKDRAAKRMILDAEARGMLKPGMTIVERTSGNTGTALALLGASRGYKVIATMPSIVVKAKSDSLRGLGADVHLQKSGAILDKENHFYHVAHRLSRENDDVVFLNQFDNLVNMRAHYESTGPEIWHQTNGKVDGFVCASGTAGTIAGVSKFLKEKNPGCVVWVIDQEEMICAAKLANGSSKSELVDGIEIFPVVGLGPIIAEGIAVPFVTRNFHEARIDSGIVGSNLEVVSIAHLLLKHDVIFVGPSAALNVLGAVKMAQKLGPGHTIVTVLCDGGERYRSKLYNDEWLQGQNWMPTLSNPPALDFIKPLVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNE1</accession>
    <name>A0A8K1FNE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Purple acid phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011438</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNE1"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778:SF7">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488615" description="Purple acid phosphatase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="10">
        <location>
            <begin position="184"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="8">
        <location>
            <begin position="303"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="9">
        <location>
            <begin position="556"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="626" mass="69880" checksum="8445BEAC863BF3B4" modified="2022-08-03" version="1">MRSIFVSAALVALLATSTLAEEQRNHANDYIRGGTWLYHEDDGPCGRDPLRLNCSFAPTQVANSTSLNIALAAESVTLTVSRRMIKHLDPLDVKIQLNGVTGTDQDWVGAYCIDNPQSQVPLADKEYIDYQYTTAAVDGVLHFGPLVNMRCTWQFRYFTMRNGNWYYKLGESPYVTFEKGPQEPLHVHVASTSNSLEMKIMWVSASVPKPQVEFGLSADKLTHRATGTGETYAASDMCQSPATQVAANLYRNPGMMYSATIAPLMPGLTYYYRVSGGDSTPKSQVFKLKTPPSPGAHNGPASFIVYGDLGDWNIHATGKLPDDRTATTMQLVRRDLNDPNRNYAAVMHYGDLSYAMGKTYLWDQFGAVIQPVASEIPYMVGVGNHEYCYTTGGEKDPSGAGGGGFHPPEGNYGTDSQGECGVPTHKRFKMPNNGNNVFWWSVEMGLVHHTMVSSEHDYTVGSTMYKWIEKDLRSVNRAKTPWVFMHIHRPMYTSEQYESDHRVALLIRKHLEPLLAKYKVDIVFSGHYHAYELTCPVYLDSCRSEKLPNGLEKAKAPVHIMVGSAGADVDNVGYYDVPWRVDAILDYGYGRIHVYNETHAQFEFVLNRHGNVASSAWIISDHDWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP60</accession>
    <name>A0A8K1FP60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP60"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016206">
        <property type="term" value="F:catechol O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="25800" checksum="5A6AE8D9B6268D7D" modified="2022-08-03" version="1">MSSTSPRRADWRQQVELRPSQCLAYVKEHAEQDNPQSVLDTIDEFCTKNPMMNIGRTKGAIIDEHIRQTRPLVMAELGGYSGYSAVRFASLQKEVAGPEAHYYSFEYSPEFAEIIREMVAFAGLSNHVTVVKGPFADQYETIKSKTVDIYFIDHEKTCYLSDAQLILNSGTLRKGSLLIADNVLRPGAPDYLAFMEDHKQFVTTRNVVEWPGRDGSPVQDIVLVSEFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPL8</accession>
    <name>A0A8K1FPL8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPL8"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF2">
        <property type="entry name" value="NLR FAMILY CARD DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="568"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="603"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="631" mass="69627" checksum="25C1C1059AA33D9E" modified="2022-08-03" version="1">MATVARFPLPHAAMEEPDARRFLPPPDIHPNNAVFGAVSLPKPLTWQRREHMVQRRNILGRIGQLLKRNAQLVVNADGNQEEHEAQSKTWALARKIEVLIFLNSASLLEYSNVDSLARRVQAMTTSIVNKKIRRQVGGNPSTSRCGSPPAPVFPEAAPAPRVSVTAAIATTAAPYPMDPVPAMPLASLAVVAPVVMQPVAGPASPAPSTPSSILPSIGRLVPKRSAAEMVTSPRLFGGFPDRETKRARRSVELGQLLLRGYDEISKMVWSYVDGVQIMRCRQINRTAQVLVPMFVTSLELSCNSIQQALATPSSITGGCILRECVNLKHLEVVSLSSGMTFGKLSMRAMNCPQRFVVTHDDHEQIVLALSEQLRFNAFPQLTRLGLTCLFTNEEADGEADVLLNNLMTGCCPQLQELCLPGNSFGDYGAMKVAQMLRSRVCPKLTRLDLRRNFIAEEGLRSICHALADGCAPDLVELCLGGNTITDSCFHHILFAMESRQLTQLRFLGIEMNYLTATSMEMLGRTIGKMVCPQLSQISYSDNSVDNTEAKRLIATTVYQERVLRQRQQQLRRQQSQMNGGQVAFGSDVQHPQLQQHAMATRYGESHMRRSMEAHDSSGEDDDDDHYSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPZ2</accession>
    <name>A0A8K1FPZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003868</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPZ2"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051837">
        <property type="entry name" value="SortingNexin/PXDomain-PKLike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22999">
        <property type="entry name" value="PX SERINE/THREONINE KINASE PXK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22999:SF23">
        <property type="entry name" value="SORTING NEXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="130" mass="15510" checksum="543A70C746BC7823" modified="2022-08-03" version="1">MALVYLPEKTWSPRYGPEFFTVAIIGVDIHERTYARYKIMIQNGKKHWTLLRRFSEFDKMRSSVQSKKGRDIPPLPPKTFWCRDLNPEYLVRRKALLYEFLNDLLVIPHVTEENGVRDFLQLQSSKTFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ97</accession>
    <name>A0A8K1FQ97_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ97"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="48460" checksum="F45B51AF93FA60A9" modified="2022-08-03" version="1">MTDDACLADIARWLDDTWTEDAEFPALALEEEDATVLLNTVVETVSSPTQSTTTDKAESPLSTASSSSRKKRRQGYNPNKARDARRFELLELRRAAAQLEELVQKLQVQKENGTLPARALSGTIGIWRNIAKRQLAERTRSEELNGRLKIALDDHIRHTKSLERTLRKLFASQGLEFVLPKDLSINTIQFRDPFSELCRDTDARYYDIDSLFQRLGIRDKEQSQRDVQARHGPRGMEVEICQIEVMPVQYQVAGEFVWQRCGEYMRHIPFRQYYERTSAGMTPSHDTDYERITMGLKSHTTADINSLQVKRFFTDDKRAVIMWSATIIPQTFAGKDVTGLSFLERGTMIFEPPTSLDPESYSIFRLWVSFSPSSSDETVPLDSVLVSKVTEFVYAHGATMATSMYQALENMLMHEVVTKKLGFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQR8</accession>
    <name>A0A8K1FQR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQR8"/>
    <dbReference type="OrthoDB" id="5872154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="467"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="572"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="621" mass="68388" checksum="8A4AE408664AAE2A" modified="2022-08-03" version="1">MGRPRNSSNPMRPTRLLKTASSGNVGVMNLHLPPLSTASITRSLEEDLESQARSAISLFGFGSAERAVMWSRVSANSFDISGFGGSNISPSLMLMERVCPIGTNQLLWNTMHNGETITNLGTASNNHPSDNQDTESNSSNGNPSGDEEHGEWDGQNYTHLFASRVLQQYLVKGVTTIPATLEEVIDLLVRSDSDDMETTMQHLVGVKASGSGLIYRRRKKRLRRRHLPTATSAQRLGAKSLSAATMTYESDSSSSSSGGESEESDNQIHQKLNRMSMAQTRMSMAANANVSTKSRKVTNASSAPTATSYMDDYQTLMAETGNRGNLSIKWVVGERAARMFAARVQYCLLDYECIIVNDWDEEDCSPMYVRSIQSCYLPQCQPWMDEFGARPTDLQPTGFMVREAKNRDGFVEIQFVASVLEKAQLPNLSRRAKLRQLVAKIARLEEIVTSRRLSQSLLTHQPLWVRNRERTVCYGCEAKFNISRRRHHCRLCGEICCSDCCPKMDVALPDVGVTSVRVCVRCVRKRRQSSDSIGSASSFSNAFPSSYSPSKSMSGTFYHTPPPPPPPPQPALAPHLQLSSSSSSEYLSSSQGSISSSYGAPLGERKPSSFGSSMLQRFKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQU9</accession>
    <name>A0A8K1FQU9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001965</name>
        <name evidence="3" type="ORF">Poli38472_001966</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQU9"/>
    <dbReference type="OrthoDB" id="163623at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036433892" evidence="1">
        <location>
            <begin position="22"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="22145" checksum="FB7616DCD067CE82" modified="2022-08-03" version="1">MKTIHAALPLAVSLVLGQALADKYSAVCIFDELKCGGDIQLREYAPAKDGGCKSGSCTPVPTKDSKFSFLPTCTDDIVKDTEAHLGGRSYVIVQFYDGEGCAGDFSSALAVATNGKCYPTSDGKTSYQVSTNSTSVNWTKFMGTDCAGSNGTTVSFNVSSADGSTCLPGNIKALASIEGAAPVEGAPSPVPSPSSAVGVAPSILAVGVAAASAAALSVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FT79</accession>
    <name>A0A8K1FT79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FT79"/>
    <dbReference type="OrthoDB" id="41362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050461">
        <property type="entry name" value="Nitroreductase_HadB/RutE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43543">
        <property type="entry name" value="MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43543:SF1">
        <property type="entry name" value="MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="23985" checksum="CEBFB917A15C13BA" modified="2022-08-03" version="1">MMTTSDLRQVIEERVSVVEFAKTPIPDTVLADLLRLTQRAPTSFNTQPYRAVILRTAEDRTRLSEAMLASNVAKVKGAPLVVAFVADLEPSKEIPRNQQLMRDAGIPEAYINVLPTFLKGFSGEGTPAGLAWSYKQTTFAAATFIFAARALGLVTRPIEGFDQEKLKTALGLTERYSVPVVVSVGYPKGDLPAKSSLRFNPAEVFFEGTLGSLMSGLFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C326</accession>
    <name>A0A8K1C326_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C326"/>
    <dbReference type="OrthoDB" id="76256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="113" mass="12638" checksum="3B68FEFE82EE2DA5" modified="2022-08-03" version="1">MASKITTISLSTKDYQDGGEAMTSRHRVKIYFQDDALRERSQANSQQLLTPASGPDGDNDNSAFMAKKALKYRKVFERMSGVDVNSPGFDASKFLGVEWCKTICLKTYCEDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X4</accession>
    <name>A0A8K1C4X4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X4"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="60439" checksum="949642152951F6B8" modified="2022-08-03" version="1">MMEALRTASSLEELKKEPWRLQIQADTTAEQLRGLVLKNYHVFIRSNQCAAVVKGELHELKEQTTEIMREIPELKEFSTHTQEETAQIVTKHGDIQFVFDHYLQLTELLEIPQLLEACIHNELFDSALDVIQFAKETFEDNSKVSNVVIQALVREVTQMTGVLREKLLQKLREDLQLALCVRIVSFLRRLDALTDGSGHVGSIDHERQLKEEFLSCRSAWLASLTRTITTNDPYQYTVQLIDVKRTSWFDMITQYSAIFGNETVDGKVDPPLCRWATSTVADFIQILMKQLPKIDDFSSLATILEQSLFFGGSLGRVGVDFRAILVVYFEDHIVELLASSWQTACRDFKANLSLHALGGGGSTMSATPIVLASYRNSMNGNGSGTASPFQPRVPSNDEDVSPPRVLMSFPLLAEFTNALLTSFNDLRLCTLASLNSRLAGRLHQTLATLVLCVHEFCVKNSLLVDQDGAKSSKAASLHDAVSDMNEVIASDLLPYVARCFQRLFPSVNIRSSSLAALNVLALLELMRERQLLRPVDANET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C557</accession>
    <name>A0A8K1C557_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C557"/>
    <dbReference type="OrthoDB" id="113225at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="29014" checksum="9E5C1F83CE26FE79" modified="2022-08-03" version="1">MMELDRSDPQLEMLFSPMTQRGQERFARARAAIRQHYGPAAQLIQAQQNSGKVEAPQIQRMRLRIREAANVSADEIFFQSFGQPEELLSVKNEFAREELPEVEDEETTSTSVGSSREYGGYSSLSARSSADVPVSSKFGFSSSHATGHVSQLAPPTHLRTPTRLSLKRQRTSDDSAEKMLPQRKARITLADTTNIVHTNAWQRHGSMSSTSTVSSIVKPFGAPSLSSTSSVSSSTAQPSMMSRSSQPTTAKFPSAINSRMFALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5E6</accession>
    <name>A0A8K1C5E6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lysosomal Pro-X carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006758</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5E6"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000007">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF38">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="67249" checksum="772AE5168A04EAC2" modified="2022-08-03" version="1">MLESNTWGMPVSRVNREVEESDTMASTMESSPLMDRVSTPRTRPVPGSPRRGRRFWSQLFTHPTVNFVPARVLAFAALSVILGVVVLVNTKNLSALEGIPQSILVSGDDGLPPPPPRMKADASNCTVRYIEQKVDHFAWVGAKEQGNNSSNGTNGLPATYKQRYLVNDQFWDPSYKKAPIFFYTGNEGDVTLYANHTGLMWENAEEFKALIVFAEHRYYGESMPFGADYMKHLQYLNHEQAIADFTELIYFLQSDYKAENHPVILFGGSYGGMLSAWFRMKYPAIVHGAIAASAPIFGFPVFPEFKGDKYWEVVTRDASPETGSAENCVPNVKKSWDKIFSLAKTEEGRQKLSSIFRLCEPLSKEEEGEAVAMAVLYAFDTLAMGNFPYPSSYLTGGAADLPSWPVREACSHLAGDFTDGEDDEKLLESLREASFVFLNATQDLQCYKLPSLEDFDGIWDYQWCTEMLPQETYFNSNGETDMFWPRNITIDAITERCQQVWGTTPDPDWIRVSYGDSALRGASNIVFSNGKLDPWSSGGVHEVPKGSKLSIITIEEGAHHIDLFFSHQDDTPSIKMARKQEIAQIHIWIEEFMASGLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U4</accession>
    <name>A0A8K1C5U4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADPH--cytochrome P450 reductase</fullName>
            <ecNumber evidence="12">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_003051</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">This enzyme is required for electron transfer from NADP to cytochrome P450.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U4"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000155">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035439980" description="NADPH--cytochrome P450 reductase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="15">
        <location>
            <begin position="76"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="281"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW57126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="697" mass="77995" checksum="4212FBC949E80FB8" modified="2022-08-03" version="1">MTDSYMVIGTVLAVLASAVLFLRQPKAEDKKMKSDILKIGEQMKMYKQTAAAAAAAENANKRRESIEAGAYPGGRITILFGSQTGTAEGFAEALKKEGRKQGFEAHTMDLEEYNAQEELPKEKCVIFVMATYGEGDPTDNAVAFVKLLKGKTGKLGAEEFKGVGYTVFGLGNRQYEHFNLIGRLVDEKMEQYGAHRVYNYGEGDDDGTMDEDFDAWKERLWKELRKQFVPGAADEDDSAVATGSSADALELEYNCVEIRAPVGGVAPSSNVRMKTSTKHFFTAASAKVVVNREIRPSTEKGSTIHVEFDLKDTGVEYLTADNLAILPENLPENVERLVKRLGYDLEQWIKLEPVGDDTNGELPFPTPCTIETILTSYLGINSAPRKSPLKQLAYFARDEAEKQKLLFLASMEGKDEYQRWILDDERSFVDVLEHFKSIKMPLAALIQLVPYLTPRYYTISSSSLVNPQRVHATVSIITNKKADGRVFNGVCTTYLAGLEPLSNHTDKKKKRDSRPGEQGSKQPREWPSARIFVRPSTFRLPKDPKTPIILIGPGTGIAPMRAFLHERAHMQKNGVEVGKSILYFGCRRQDDDYIYRDELEGFQASGVLTELHLAFSREQSKKVYVQHLLEQQGEKVWELIGQEGAYVFVCGATTMGNDVQKVLHEVVQKHGNQSSEQAQATLKKLQDSHRYVQELWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y3</accession>
    <name>A0A8K1C5Y3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002966</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y3"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="303"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="390"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="442"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="500"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="553"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="607"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="253"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="722" mass="76640" checksum="7D4E4F2171D9792C" modified="2022-08-03" version="1">MPPPTHSTRPPLATHLFSSRVDRAALKAGLHRRNGIHVGGAQSMRPSVGFSCHKLNVTVDGCAAFYSAVLSAAPESPVTISPGSLPTCIRITPTVHVFTKDNWMKPQFFRISAVTTSAFDDAASSNGGNSKVDRKFLQVIEHFSSSADPRFGGNRLLYAPASILVYVTPREGSYIFTSGRALGTAKQVGKSIVNEIHHAFVSLEHGIPVRGQPKDLVARSSMITMQSAHTTAATAAAVAAVQAANTATQAAATRRMSSKRNLFGPPTPVSDVVSVSSGSTGLGSGPNTAGPLGGEMMDGMFQHLSKDAHSFTKVVCRKNQTILLQRNGQMIALGKRDVDTSGSSLAPGSPRQRGKDGSSDPDSISDAALCNMLADVDCGDDHAMAITEQGYLLSWGNGKDGRLGHGTEDSRESPRLVKALFHKRIVHVACGARHSFVLAEDGDVFSWGDGRAGALGHGMNPESRTLDSVVAPLEVLTLKQKGVVKISCGDMHTAVVLINGSLLTCGWAEHGRLGRPYSKDDYSSYFAPVDLKGHLCTYVVCGGAHTLGLTESKAIFAFGSNSSGQLGLGDCRHRSAPALLTYFDDDHAVVTGIAAGKMHSSATTQDGRLFAWGSDEFGQCGIGSFPQLYTAPHLVASTVGLGVTQVGGGDGHSVVLCQGSHRHLDALEANHPTRYSDLMDKFELLLHHVQAKPGQHKNEKFQEETRCMLWASSVVYNHSRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6S3</accession>
    <name>A0A8K1C6S3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proline-rich protein PRCC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6S3"/>
    <dbReference type="OrthoDB" id="206969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018800">
        <property type="entry name" value="PRCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621:SF2">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10253">
        <property type="entry name" value="PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35535" checksum="0EC7FFB9A62DDEFC" modified="2022-08-03" version="1">MSLLVPDYSSSSDDEEAPRVTKTSVAKSPVSAASNEVSTAAPRAETVTKSPSEPKPRKSKKTKKGKKTTLFLPPEIQKLLETGTFEDSDDDLDGDHLLAKHRRAAAKRPRPETKSSTPLEKTSLSFLPAPKHQLDEPTQVVRPEAPAVSVESVQTPATESGEVPAYDAAAYEQYYYQQQQYAQYYQQQGAYDYPEASGEAEEQGSSKRARHLDRELERMLQQGQFASVADKIVEVQGPAPNAWQAPVDQNKGNPSEMKLKASFWNTSAGGTVASAKPSRLQRQKHQLNQLAFDAKAREFELLDRKGSSIKTKRETHAKYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6U3</accession>
    <name>A0A8K1C6U3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6U3"/>
    <dbReference type="OrthoDB" id="123265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="563" mass="64281" checksum="F0802BD624A3B0FB" modified="2022-08-03" version="1">MRIASVPDTGLCADAVEDEALQQVYYEIVQAQLHPVVNMYKPVKTAILSASGARVFTRFQRRYGKLAAILFLVGLVPSAAMFFVPARIGRPLAVLASALELPIMLIAVMSLRLDMVRVLVRTYEFWFFSTMSVAGMFSMGWYLRDMRSVQVGVIWIGNMFVIVADANVHGLNRMHTIMLVSVIYNIILVVFVLLELIEETHSFRVFRYGAQCVKTEDVVSTAFSAVIYLQVRSIYRKRMKKKRVENAQRAIHCASYRCKVKLRQLRSARCLSLLTPNAITVTYRPAIVEETVASPMEYVKIDRVFDARHTICGHRLSFDPWCPYRRFVVKACGVLGLGLNVSLFIYLNYVPDYPQIASGLALVAFGCSAVFCLACFALYNPALLRHLCFSFDFFFLSFQLVAMHISACDVFYWDPRAIVLLTSLVWTHWVLTIDALMPLARNNLGFQLWYCAPVLLSLLVGQVLFMYETSGDTKWNIRDRTIFTLHALNRSIDVRVMPLLFTRVWIMLIWECRVLWRIYYAQATDLIIVHGAVALNLTRIAPRLSHMRVMQSDDCTTTADSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6W6</accession>
    <name>A0A8K1C6W6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6W6"/>
    <dbReference type="OrthoDB" id="167909at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="249" mass="27145" checksum="3B10090F8A8BE2DF" modified="2022-08-03" version="1">MGDDHLLNMDPSLMTERQQLAFLLRKTAQEQSGAESMSQSSSSSEDEGPSRKAAKTTKKRIPRSTATMAKSSPRNARKTPVHDEASANAARTTHGVVIYSGRGRPPKNSIKLAPGQSAADYEKIVAKSPTNRLLTDAEARQGDLKPTKKLQVKTSTSPRTTSLKEELEHRFDFKSDKPVSSSEKTSPSSTSDVAHMDVFEDHAGQPDFWSLHCALCCQSTSPFAASSEALFLCTSCDKKYPTQRALGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6X5</accession>
    <name>A0A8K1C6X5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000131">
        <property type="protein sequence ID" value="TMW57667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6X5"/>
    <dbReference type="OrthoDB" id="1713632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="17499" checksum="F2F44405F29F5402" modified="2022-08-03" version="1">MRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIKMNCLDAEEEHPLQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDNTKPRIHLPRPCRRRRRRRRKHRPRLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C738</accession>
    <name>A0A8K1C738_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C738"/>
    <dbReference type="OrthoDB" id="547796at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="33"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="136"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="236" mass="26236" checksum="F63AE01BDE41D26C" modified="2022-08-03" version="1">MGNSLGTPPTGPNSLPRRGSKATEAKEDTRRYFTKRDLAKFNGESDRPIYIGLLGEVYDVTSHRNQYGPGGPCAAFAGKEASRALATMSMNDEDLDSLDLSDLSDEYIDALHRWMKRFQEEDKYPNVGRFLVHQDMTLNELHKYNGVDDVRGTVLIAINGTIYDVTLNGLQHYGPDGTYAQFAGHDVTRALACMSLDPEVLEDPHTDDLTAEQQSSLADWATRFQQKYAPVGKLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7L6</accession>
    <name>A0A8K1C7L6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7L6"/>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032723">
        <property type="entry name" value="Deaminase_LmjF365940"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14421">
        <property type="entry name" value="LmjF365940-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="617" mass="69426" checksum="A518F041DBC0AE7A" modified="2022-08-03" version="1">MEFLVHNISHSDLIVELSWLRDEGTASENAASNGENAASRTNGHQRQVVLEDGSRVPLTVLARPKFSHFQQTSKAIMDRVEELREANAASPPAEQAQDNGGSTSPSKSRAAQLHPSLLGIAPEYAGAQRRVRWKAKCDDTKYPIGFNLHECPIPVTDLHDFRLRGGIDMVELAQKHWKRVCITAVYFPLIALLLPKWQQVLKEFKSDSSKQLVYLISGAGIPRNVEHNMQGNSTEITAKLISNFVHQYYPQVEVRQVHSGSNIFRFDDNVQFMTRELRPRLEAHRETIVDRCGEAWPSHFHVTIAYADGPPARLSALNASLRIFRPSYLHVWQLKTYWHEQKLSMDDVDFHAFENIEASPCVSFTGADSMTQTLVKEMRTFRDQFLQGEGMGEVESFWLRKSRKPVLAVLLIEKEDEFGNKTLVTYRGMNCEVSMPTGSLCAERNAIGSALAQDPNLRRRSLKMIGVLGLNLDGKRSDGVSAFEGIQHIESPNQSSAKEDDDKLASLVESDEATSTHESGSIEVQLSPVLPIKSPPKRVRENSNYTSPRKPKRPRTFSCDSTSIEPVVLLDQLDRNPLAPCGACKEWLVKIAESNPSFRVVTFENARCRNFYINQIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T8</accession>
    <name>A0A8K1C7T8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T8"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="3">
        <location>
            <begin position="61"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="13639" checksum="75E19E2C183B32BE" modified="2022-08-03" version="1">MSFFGFGKSKAPEPETPSYSYEEPSYDYSSSSSGSSFDTAPSSSLGGASSAGVGVAEVQSMLMEEQERALIQQAISKITAIAWDKCSASKPDQDLSSRERECIKNVTLAYLDTSMFVVHRLNKSGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7V8</accession>
    <name>A0A8K1C7V8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7V8"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="252"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="497"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="668"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="88725" checksum="C5378B2212BB6635" modified="2022-08-03" version="1">MGCVESKVAALPSSSPQSREPFAVVAGSNAASGTSTVVSSFSSAASSAFCCTKKNRTAPAEAVPTTAASAPSAVQRSPTIDDLSLAKGTKTQPTPTAKTATGPPTVLLPPVNKAVTLENVSYDELCTHLLKSVKNGDLKAVVRIVEVARAKHANATPSIVDVRGMWESTPLIYACQYVHEPIALWLLDANANANAHLVNERGVTALLLASLEGMTAVVERILAQHKLKASEDIIPLDQQIGVVYNAVADLNVRVNPLLAASMNGHHEIARLLLKHGAAVNLCVSSSTGPNNASGSTISSGGTASARQYPLLLAAKYGHSSVTQLLIKRGADFATRDANESHALLLACESNQEDCALGLLNLLPKTHSAPYVAAWKRANCHGFTALHYAAVHGLVAVASLMLQDDGLQWGQDKAFLNATSATRRESALLMACRKRQLEVARVLLQCGADAHVADRGGTSALDVLKREKRDELLQLWCEMQLRHTRKLTVTAVDGGVIASSAEETTGTPQGTSSMKEEQQTEERVVENTEDNQSTEVDHEEKVETSAMTEPTTTSDKTAAVVSREREEATVNNEEKEEGEEPSTITAQDHVSTIAIEPAENAATNDQTVESSLDSRPIKPIEKEEQSTEKIVEEATLSAETVEEDAGDASIPPVLSEPESVSMAQDDGAAESHVEALREPPHEHSDSAETTNEANDDQSDVMGSRINGAHDSVPVSADASGDNAVEEQPPTFDSLKPTPLLSPVVVDSPARVPTEVLAEPAHEAERVGHSEIPAIEEGDAEAASPKKEKRKKKKKVTKRKTKERAAPRETQEGEVEEEEQRPPPVTAVDELDGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8K5</accession>
    <name>A0A8K1C8K5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8K5"/>
    <dbReference type="OrthoDB" id="97510at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="35942" checksum="1BB8839F84620F15" modified="2022-08-03" version="1">MEETRSELDSMLLELFGEAESTRHLSSDKDMASDVRERNRMSVQRYYYRQIVRLENRCRQILQGKRTASIHPTADSGEQLSTAQRLHLAYAELVMLCEDLGREKEELLRVLADNITTEKRPCRIFLLQRRRTAAINAILEERQQHPAIKIRTVTAGEFHETAQSAYQHIMDFRQRIETFTSDVTAFGSRDRYHYEKERLQFSLKKTLLHHSFDDASEKMWRLVNDGEALAQIYPAKLRTVFHPVQTLDSNNLIYFQTIQLDTRSDYRNKCLLLYTRVSAMNGDGCLMLFRSLDPCKYVLHEGKISEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8U7</accession>
    <name>A0A8K1C8U7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elicitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006953</name>
        <name evidence="10" type="ORF">Poli38472_006954</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8U7"/>
    <dbReference type="OrthoDB" id="119990at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035645311" description="Elicitin" evidence="8">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="139" mass="14088" checksum="6986B66465075AF0" modified="2022-08-03" version="1">MKFLAVAFAATIAVATADDCSIDALSALLKNTNLQKCGTEASYSFVPPTKPTEAQLKGMCASAACNALLADVQKLNLAECTVPLGDKIKLRADLIDYAANYCKSSGPAPTPGPGPLPTPSTSGTTPGVTPSVTTAKPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C969</accession>
    <name>A0A8K1C969_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C969"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="115"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="19155" checksum="D2B2DD0E4CCE3286" modified="2022-08-03" version="1">MEMTSKAAAAVMENATSVRAFGCVEEMETKRMVVETMVAVERALQSRKRRRQSDERPVQLPHEKRRRMLLARRMQHTQSHALDVSAFLRQRQQQQQQQQEETPCASGSDPNERVCAICLDGLSTATREAIPCGHVFHRHCIRQWAQYKTCCPIDRLDFDVAARPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9B5</accession>
    <name>A0A8K1C9B5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9B5"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="750" mass="85699" checksum="D098D235B9A3C53D" modified="2022-08-03" version="1">MTDLRALLGGEWFLQSLVTLLTHEDAICLTLLAVECGLEFVRHTLLFKALPIAPISTQEVAKYAAARGWWHLLVQLPLNNRGKHQEAVSIASNGHETALKRCQRLHTLDFPAHVLFAAVRRGVMEEVEWLHRCTRYDPEEAIMCAAKARQLGVLKWLVVTPEAETRGFKLLVRLEDSSLNVVCWQYTTFERTLVYCATAEHGLLPPRLYVPDETESSWVAFAELEYVSGQVRYPLMDFAAKSGNLEYIKRLQNDPVGSTLYFQAMCSAIQAGHLDIVRWLHKHRPEHPESPADLLSAAAQKDQVRIMDWVETQYDLTDSISTAYTMAISTQAANATRWLVDKFADTLCQVERPAPNLLLSFPPDLIEQICAIHGFKMNLSFLHTVASLGEYEVMHWLLQQDNNNIDEYLPHQEDRSSLLISAIHGKNLEIVRWCVEELGSWSNLAFKTSVVCGALPLAKYLHEKTNERMEIDTSLSREQLLETQARLLEQLLIEAIRCRFIEIVEWLVEELGAWSVFGLQYAAGSNFSYLVEKTRQRAQAGNTTLMAQNPFSDHRILVMLLDRSGVEDDSLEWVLENYPDTDITPATFSAEPFLMEPERPWHVFRKVLRYRPGMCVRWSRFPSLAVQFGSLADLQRLEVIGHPDLFTQETLDKILKFSRDEAVMRWFLDRFGSPVSNRVLEWTARYGAAQLLEAQLESRLNGPAEISVDAMQQKRFDTMVLASELACIAAEYEHTQCREVLTRWIHAHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9W9</accession>
    <name>A0A8K1C9W9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9W9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="118" mass="13828" checksum="44E51428FF02FE7E" modified="2022-08-03" version="1">MCRPVKIWNDDESLPFVQTTYPVSHKRCRREPPVVSPINKKPKCVRVMWRVSQAQRRQDEEEEEEEDATGRTDDDMLEELENVRRLQDSVNMLQCQVDTAAQQIKELRALLQLSMASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA91</accession>
    <name>A0A8K1CA91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA91"/>
    <dbReference type="OrthoDB" id="67499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="25368" checksum="7ADAF6B35C3ABAFA" modified="2022-08-03" version="1">MSLAPKINQQPFKEQLKHRQQQSLVSLRGLDEGNTSRDTTERAVESESHEYTQNCTQYHRSDEVLLSAVDAGRLDELEQYYQLCGDNVDVEVMERVLQVAVTHHHLPILEWAHKKKETSGWSSKLMDVAIENDHFEIVQFLHEKRNQGCTVRAFEEAIKRQQVKTVNYLYEHRPELIQWPQLEHASMLKDLLLSWHPYDKEILDCVLRFRRERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK9</accession>
    <name>A0A8K1CAK9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK9"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="748" mass="84786" checksum="4A96A782D5D944A9" modified="2022-08-03" version="1">MPSLQTRAKKRLTVRRIFLLVLNIASTALTLLTGLRENPVIVFVSGRYDGIRSRMREGMLSYGIVQDDVVDIDKLPDLIVAADDYRIFSAPRRSPDNLAEDRSTCMRVNSMNVTVMTLNYDDFWGKGPRRTQIFLYSISAKRCGLINFRSEWVEGCIDDHQGNETQCHEYILKNFDELTQDRAIQAGIEQDFGEPGIPFLKCRGRPEREFTFNTDLMVQQSFWAGGAYHVEIQTSECLAQPLLRDSKWVWGLFQVEQADQAANVVVALPKSGWFGTIVTFAYGIVSITMIGHGILAAFVRSRAVPYLPDSLRSTREHTVAKFLAPFMSVTTLLAENENTIITFKGSILMASDVWMNHWLYITLSVLDAVINVRMTYVILEMGTWMLGKKANFENFIFLCSALTRITWVMCLAHSITRLFFKFILRSLKTLKVVRSNIRDKLEWYVDATALFMSYKIYNLLLCVLLYLFLEFHGGTTFMKQQPWYKQGMYGGTQSIAQFWGNEIICDFFVMLSILTALGWAISVAILQTKYRYLANNGVIRLLQYRYVLVGWDALTAAQVLGIDPYNPMLVDKDVALTSCSIGSLLQLLYASGPSGLVHLAGDYLFVDGGFAKGAVDFHYPVKRAMSIGLYIPSRMSVYQTDKGSTNDYASNLTNHTKQRHRADAEITDRTSAEPTQHLEKHSLFDRRLRVCAEGFLGKMILVDVTEAGSVVKNQETGRREFVVQDALAFMTILDIKPVLNGDKKLHME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBR2</accession>
    <name>A0A8K1CBR2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBR2"/>
    <dbReference type="OrthoDB" id="58578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899">
        <property type="entry name" value="DOMAIN OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899:SF1">
        <property type="entry name" value="PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="29134" checksum="5D91D969D8B5A518" modified="2022-08-03" version="1">MASTLAFNAPFLASAASPASPRLADASTSLHGVMLAWEDVLAPITLLGCRVGLTNSNQALQNAQLQLAQDVYLQQALAGIEEQMLQLITTAATLGPVYIVTSKSLKFMELSCSLFFPRLAAFLLQANMTSSVGLLAKLQQHRVQVIAAPRKFTTAVEEATWRLTVFQQICVDVAVQRALMLGAPLPTTQSQSQLLLRDFEVGRFGLISLSALEVDTPICVKALEATAPFAVPKCVQVSSEMSLEAFFAQLQTLKRYVGSAAAQTNAFATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBX2</accession>
    <name>A0A8K1CBX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBX2"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPRY" evidence="2">
        <location>
            <begin position="189"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="55255" checksum="21359DDDC2A9D6C4" modified="2022-08-03" version="1">MPSTATASSRFSALHEELLAQVLSYASARDVEAMAVASKFVAHEVLPRFPIWKEIFLYRWEMLNFALHGVKEGEVTLEIAERVKKLFPSTCSESRMYQLLAHAVTPVPSYADVRATNRLRMASRMLHYVDTLGGAKRREVMDFAFSGRFLGGDRCVRSNVPFPTTFHVAVYARTLPNKQKTFVIGVTASGYYEISISKRPRQAADSVTGSRRYHGSDMTSVGIATSRFPLLDKQPGWDSHSIGYHGDDGRLFRRQSHGRPYAASFGPGDTIGCGVWRVPRAAESSVYFTNNGEPVPDGDRDIECDHIPWYPVVGLDSFDAIHINFGQEPFKFDDVVDMMFDECEGESALLATQLQWYTISESDAESSDDDSLDISESEDGEDMEVPYEMIEEHFERFEDDEWLPDPDPDGDEDYDGEEDMEGDVELETEEERDGAIGPRRIRRRRMTADAVVTTPNYEQFVSQVSSIFWVALSPFLPLQRLATKRIMTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBY6</accession>
    <name>A0A8K1CBY6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBY6"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF18">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="32583" checksum="03070220F50C6272" modified="2022-08-03" version="1">MEGTSRPSKAMNVGLNLTLSSDLLAPAPTPAPPAPVYGTLPSLNPPAFFEIVEDQVYRSNKCDSSSFPFLATLQLNTVVYLSYDELSRELTDFFKEKEVNVIHLGLKYRTSSHWKGISEGITKEAIELMLDQRRHPIMVMCKTGVHFSGTVIGCLRRLQNWSLTATIDKYRNLASNIKTRFENEQFIELFDVDLVTLPQNLPDWFVLNQQLMEEERVALTKAECFPGIPRSTPKGKVLLGGGTTVQVADALSDKNNVPAYQRFYFQVQGPLTSPSVKFSEKKSIIGDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDJ5</accession>
    <name>A0A8K1CDJ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_012640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDJ5"/>
    <dbReference type="OrthoDB" id="2020972at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18007">
        <property type="entry name" value="DEXHc_ATRX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="212"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="625"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="560"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="826"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1190"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="826"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1190"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1232"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1246"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1259"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1269" mass="141964" checksum="ED673B04EC6F7A44" modified="2022-08-03" version="1">MMAASTLASRMIDVDEDMSASDEAEWTSRTDRRAPNSNNNDDADDFEALADDDDGLRDFIVDDVDDNMDGVDEGRPRRKRRHSQRDDEEMSQAEESDGNGEGTERSERSHRRNRLRRREIAAVLDDDDLEESTRLAREAEQARARHLFQVPVDEAAVAEPTTYVCLNPRPEDRKPPDGEVGSPDQPVFVHPDISPKLKPHQVLGAQFLWSHVAVEPNGFGCVLADFMGLGKTLQVITVVQAFLALHTRRMSDGSLKPRHKHVLILAPTICVRNWEAEVVKWLGKKEARKIGVHTLESSREKKMADRVHVVKQWHRRGGLLIMGYELYRILVLQSSGEEKIAAGNSKVAHLIKEVYKCLSDPGPDLIVLDEGHRVRDHKSKLVKALSHVKTARRIILTGYPLQNHLEEYWTMVNFARPDYLGSLEDFKNRFVNPIENGQCIDKYLFRQLPPKKEWVLLCKLTDPQATLYRHFLERGVPKRGELLPGVGGKVDVLGGYHISLAISNHPDVLQETYHQLEESVRTGKIGNATAARGRPRNGGGDDEEDLLNYLAREMTAANGNARRISTGDDDDDDDDESLLDELNAPRRGGGGNRGSTPFEHRLGFARDFMMQYTNGHLESSGKMMILMELLSECKAIDDRVILFSQSIPTLNTTEKMIAQYNRRQTRHSNRIHYLRIDGSTPQLERFRMIGQFNDWDEEIDLIMISTKAGGEGVNLCAGNRIIIFDVCWNPCNDSQSMCRSYRFGQVKPVFVYRFVSAGTMEKKVYDLQIRKEGVAKRIVDEKALERKFKNADLQNYFNIDDFEDAMRQQSTVLQQIGELASISGVKDNDSAEVDPSKPHSDAVAPGCVPGGKPLPQEDRVLETVLKRMKEKQKGWVLDWFEQETMFEETIDDQCTEAEQEEITASYKYVKALRRMTRSGVQMSREGTLLVTCGHCRVPNYVYPESVTKVPVPKYIECQYCQRPTETQGALPFAQAQAQAQAQIQANSGAGGPIGSSALGVVRNVFGLPPSMTVDTGVQPLGIGVSVSGNIGGRVLPPHLYSIYQQQGTPGAPVANPTAAPSIPVASVTHGELIRRQLEQQQRELDRRHRERQNMKLGDRHLLVLRRGMNKSQELKRQAQECGATIGIEVNSLLTDIVSAMSLDETLKWLRLTKLPRDVEFHSDDWLRQEIAKEKGLATKPAPAAPSTVYTFGSGLSQPQPAQSQNVSPTIISPGDTSHDTISIDSDSDDDVSVTPATVPASASTTDRASLPSQVNTVEQNEEEDIIEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEN8</accession>
    <name>A0A8K1CEN8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEN8"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF140">
        <property type="entry name" value="ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="38074" checksum="9B58DCE1BF23AAB0" modified="2022-08-03" version="1">MDAVVVSSSVAPPLAAEDVTVFKLVSLVSIWVVGLAGGLLPSLVASRQQHSPLVKHVLSVLNAFSGGVFLAGGFFHLLHSAIENPALQRWSTMDDGRYEFPYAEMFCTIGFLGLLLLEQAAHARMDDHERRSDEELEHDRDIHDSDATASDDYMESFDDEDDDPEAQTLKSFTRKKTKKHSHAHSHGSGHSHMVMSGNGGNSPAVALVLFLALSFHSVLEGLGIGAQQTSAWGVFLAIVLHKGLAAFALGSGMVQSSLSRAHVIAYMVLFSFMSIIGIIVGWIIAADSSEDSAAAGICVALASGTFIYVAVMEVIPQEFPRHAPSSPYVRRILVHKTSALCLGYAIFGLLAKWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEU5</accession>
    <name>A0A8K1CEU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Drug/Metabolite Transporter (DMT) Superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEU5"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="38350" checksum="1B9283BAD5ED1AE9" modified="2022-08-03" version="1">MNASQRFQLICFGFGQLIMFLNVITGVLSRYLTNENVSLPTLQSAFLYVSLAVVYLPIKFLYRRSHKINIPIWYYVLLALVDVEGNYFAVKAFNYANYVTVGLLLNLTVPFATFLCYFFLKTRYTWQHYLGAFISVCGSVVIFVVDYDASLNSSDGREIRGDIYCVIAALFYASSNVMIQYVVKVRDMDANIELLGFLGLFASIISAIQICSLELGPIEDAVFNGRVYGYMIGFVATLFVFYTVVSIFLRWSESLMFNLSLLTNPVFTVIASYFFFDEPVKAWYWFALVLFYIGLTLYTLAPAPQESHKLEAAPEESFHEVASPMVDEDTFKNTSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEU8</accession>
    <name>A0A8K1CEU8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEU8"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF193">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="409" mass="43494" checksum="14302F47ED157AB0" modified="2022-08-03" version="1">MDSLPVEEQIATLTLQEDSHLQEDTVLLHEACCKGTIDDVLKLLEQGADVNEEDSDVMTPLLLAAKVGRVDVLNVLAAHGADSSALNDSEASLIHMAASSGRVAMVEAVAALGIDATARDKNNRTALHYAAWAGQVNMMETAMMDIAMSSSGGMFDGGDVVASMVARGNVEATEAMFGVHGDCEDKEYGYHVTYSSTGEESDVISKLVKLGVDVEAKEESGKTALHFAALAGRADIVKTLLSLGANVNAADEYARMPLHCAAKYGNAETVEVLLANGAEIEAMYGDLKTPLACACRRASPDVARVLVKHGANLEGMNAMVALIIILDRNRADTMTMLLENGFDANFKYETTSVLDTAVLAGKVDVVKTLLDHGAIPSEKCDQAIQNSLRDEVYDEATAQQLRLLLHPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF79</accession>
    <name>A0A8K1CF79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF79"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="231"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="499" mass="56549" checksum="F74EC73C40E39EF9" modified="2022-08-03" version="1">MAAEVVGAVADSVLPGLGMVFSLLDTIHQKYAALKEGKELCVKLTNRLNDFAKELRQIPPETFQADVLLAKLVDLVQEFSDTVTVFADRNFVKRMLKLDKFNEAIEIYNERLDHLIRLVTIKQSDKLARLLNWREQFEQDLADTMSQLTEVVDAKNREIWMALKNMEKRMATKREIEDLVMVAKRDVSSESDPDRTPQPLDPLLNNIIKIAEKDFLNGKQVQTPPGWLIAGDEVETIGEAIDDEGLTCIFVGDWQGARVAVKKFDRVEDESPVFDKHFRVWRSLMHPHVAQLYGAGSSNGAPFFVYEYASRQSLDRCWDHLGENEIWRMLYQAALGLIYLHKKHIVHGNLSSAKLLVTEQGDIKLFGFGASYVRENNKSNTLKTDTREEFAAPECIGIGPNGAYRGDRHSARFESDVYSFGLTILEAIAKRDPFVGKSLMQIRKLKQTSALVQPDEMSDDAWTLVKQMCVCDPNQRVSLGYVAEQLKRLADGTQSNQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFR3</accession>
    <name>A0A8K1CFR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FUN14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFR3"/>
    <dbReference type="OrthoDB" id="163794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007014">
        <property type="entry name" value="FUN14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346">
        <property type="entry name" value="FUN14 DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346:SF0">
        <property type="entry name" value="RE45833P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04930">
        <property type="entry name" value="FUN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30487" checksum="D5C8CB706D519F2D" modified="2022-08-03" version="1">MLARQVLRSASRVGAKTSTQQPLRRFSRSYEPLVRRSERIPLSTARGVRESEAVPILQAITIDRFGRQHRFEYQYRQHQNDNRENAKLLAKWTTALLATGACAVSALSDDSHARAAGSSGEKSSDEEDILEQLQKKVRAFIDENLSELQKLVPGGMGDIQKQTDDFLGSGKGGQISWGFMMGICSGFALKKVSKVGAVALGSIFILFQCASYSGYIDVNHKKLERDVLNVLDINKDGEFNAKDIDEVYKRVMKVLEYSLPAGSGFAVGFLVGFRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFS4</accession>
    <name>A0A8K1CFS4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFS4"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36513">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36513:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="771" mass="87189" checksum="C4ABCCA8DA5A0B26" modified="2022-08-03" version="1">MTPTSEAAATLTERLMNTAEGSVDVPESNGGLRERTPQETLASDVGDVEFRFARTFEYMTGRRLQRRYRGVYKQYSFTAQIITWFVVLCTLSVLAAVAFGYNVSERVDPNNPTTTNLSNEIFYLVLVLVLIYLIVRVALVIRWIVYWAVFAALVGYAIMGDMEMVVWAKSTDLSEANRHARYVLTVLLVVAECLTVAIYVFTHYFYPWLVINGKFNTIWWWSVKRSDHHANTLTYRSRSRFYTRKRHTVTYTGGLDEDGRPHGYGMWTDTSFHGERLTGQWEHGLPIGPYRSFEHGSGYCFVKVRVGYCHNRAEERPDQIRFFPKHSSEGLHWGVTSVECSVSGGFFTFLPSVDHLTPIDGSSEAPQSAADCIRLLQSPVDSVVYQKGTGKRLGMSKRFKSAKRLSFSEMSNPVINVASDPVLEDREALVLLHGYNCSLDYGLDRLGQLLALGDFPTSIHPFIFSWPSGGSLAYFQARTVGSESDRTAQDFRTFLRSLVDAGYTTIHIIAHSMGARVYFHALNLHYLDDVFEIIHTNPTPREVDTRDYQPPTEPVSKRARLATLTFANADYDLKDFVKYGGGYDLSRRFCDLITLYADGLDGALFFSEIFSKKDVCGTSNFSIGRRPALIHRNPDELAESEDNPVVPHRRNMDAAISAVNQRGNFEGVTGFAYNHSLRTVSASPDLHRASIAAIEKTLDYLDMDVIDTTWMDNNVHSLRHNYFNLNPTVVDDIRNLIVSRRRAASRRGLLQTMSADNVYIFLVAPSHVKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFU0</accession>
    <name>A0A8K1CFU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFU0"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="55784" checksum="65C1B41ADF103129" modified="2022-08-03" version="1">MKFPLPRSPFPPVHLSPVQEQQYEHLIQALLDQTVSEYQSFVHVRNRVVDLTKWKHLKSRESMHVFRAFGDHSDDQLLNSQELLLDASSSSSLPISRMKMKGGSRLLGVGSIVGNLNDFLYCAVTHTEDEMQTRTSYVPDECVDWRFLYKLSGPTHDNPFKIHSIKYHVKAAPGATSYLVRPRDFLMLDCVGQMNLPNGERVAYIIYHSVDLPECEPPGGMVRGQISCCYILRQRTANSIEVYMRSICEMGGNVNDAMAATSIANALISHWKMPWGGQNRKLAWMLKQQRKRGTPEVRGAKSDHCQLCRKSYSLMRAATCCELCRKKVCTSCLTVRKISHVRPARELVQISTGFCKNCITESLLLDASEIAIQEFVAKGDTHRSMSTVNSSVSSYGSSEGIRSPRSFSQASGDSDVWSGSSRSQQIDPSIIHIETDEDRERQYQHNPLISVRTSVEDTIANQSFLTNGDPNNTKLLMQMNNLRLAAEQSRQATKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFU2</accession>
    <name>A0A8K1CFU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFU2"/>
    <dbReference type="OrthoDB" id="10249567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="126"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="36164" checksum="598B278205C80C85" modified="2022-08-03" version="1">MNRNVRPENVEFTVKAAEDLILTGTERSIIRVPASNMYSCLMQKTQRFSSLFRHYSKHHGLPRESLDFFFTSRLDPEDSPESVHLQKNDVILVRHRVVPVHVAVPVLSHDAYFGDMRQLFLSGEGSDVTFQVGPEKEVLHAHRLILTARCEIFNAMFRPGAMRESEDGIVRIQDHSPEMVSKMLEFIYTNSISDLAKLSSSQLIDLLTLSEQYLLQPLKHLCELAARDALTISNVGRFLCAAEKYNAMYLKDFCLNYFTEHMADIVEDENFREELESYPSLALTVLRASTRSFSSTSEPACKRRRLNMPFDETEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFX6</accession>
    <name>A0A8K1CFX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFX6"/>
    <dbReference type="OrthoDB" id="163767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="30382" checksum="F153D984251F3C4C" modified="2022-08-03" version="1">MQRAVPCVSMSPSAITKASREHPVYQGWLYVQDPRKKTFTCRFCVLDGVCFSVYTGKVDANELTGEILIRQHVLVGVKRLHFVNRGLMLIDKDAKTLYVHGNQDTAYFDQWLATFRYAISQENLRLPRLSSALIDDVVDSHATSVTGWLFVRHKVLFGRVALPTDRLYVVLTGSTLAAFKLNMEGRHADLLVQLAHVHRIASSKWIRVKTKGGSVLELRGRTEDVTSVWHERLTAVCGVDRPLASTVASTERPPLRPEPQGFLRRLSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGG4</accession>
    <name>A0A8K1CGG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glucosylceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGG4"/>
    <dbReference type="OrthoDB" id="117221at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000109">
        <property type="entry name" value="Glucosylceramidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035459755" description="Glucosylceramidase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="6">
        <location>
            <begin position="102"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="7">
        <location>
            <begin position="467"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="541"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="597"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="632"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="70467" checksum="8D1838B4FD704EDE" modified="2022-08-03" version="1">MLSPRVLTLSVALTALWTHSASSACSSYSSRYQKNLEGVCVCTATDCDEVTSEYKTLAGDSVGVFQTSKQGDRLSYTTVNASPTSNDAANIELDSSTTYQSIIGFGGAFTDSVAINVYSTNEALQKRILDAYFSENGLQYTLGRVPIGSTDFSESIYSYNPVVDDFAMEHFSIDVDKSPKSNKIALIKRALSTSSREIKLFASSWAPPVWMLRENKTENSHVKGEPGEPYWKAMALYYSKFFDAYKGEGINFWAMTTQNEPTEQALSFKQWQSLRFNADEERDFIKKDLGPLMKQNHPDLKIISYDDQKDVINRWTAPFNDPEARKYISGVGVHWYKNVDFVADFLGYFEELTKFHTANPDLFILATEACEGYLLEGVGTGAGTKLLQPETIWTRAEIYARDIINDLANFASGWTDWNMVLNTQGGPTWIGNYVDAPILIDETSGNEFYKQPMYYIMGHFSKFLPPGSVRISLIVKPADDSETTLFSKVDRVAFLTPEKQVVVIFSNRNTSPLTLKLSDAQSKRHVSIVLPANTVQTVLFPSGTSGTSAPTPTPTSSGPTPCPLPTATPTPAPTTVGPTTGPTPCPSLPTATPTPAPTTKAPTPVPTTSAPTPCPSLPTATPTPTPTTVAPTPAPTPTPTYRPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH35</accession>
    <name>A0A8K1CH35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_002385</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH35"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.30:FF:000002">
        <property type="entry name" value="NDC80, kinetochore complex component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="14">
        <location>
            <begin position="396"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="508"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="334"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW63444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="625" mass="71229" checksum="6E438981B9A49CB3" modified="2022-08-03" version="1">MRRTTLGPISSSQLNARSSVSSARVSIGPKAPVRQSIGPVGRPSIGAAQRRVSTAARLPPPAPAPRNSMSRQSVGSNAALSGRRSSVYGGRMSMAGRGARADPRPLADRTFMNSCIQALIEFLSERQYDYALSPKILKGPSKKDFCNIILFLFRQIDPTFEFGLKFEEDVAAQFKNLRYPFAISKTALVAVGSPHTWPALLGSIAWIIELLSYDEVVQNAVVDGFDSENSEKRFFEYLGNAYRAFLSGDDEQYNLMEQQEANKYDAQNQILREECDDLQRANAELRKRIEAAKVAKSSLPTLKAKKADLTSDLDKFKKLVSQLETHQTQLIGKIKEKEHERVRKEDELAERHNQIRNLQIRIDNQELSAEDVQQMSKERLRLNEQCQQVASRQKDIQNNIWRQETYIAEQMDKIESYVQQYAATATRMKLLPSMAKNAHGFDYDIEIDAHTGGVEAAQQLSVHLKQNIRAALIKFKKNRQDRTQVALDEVLQLQADVEKSREMMKMEYDEEQTMESKVRKLEDSIRREKEGREASISQKLSTTEDVELQIEAILNERDFATEENQSRKHHENLKKSFAAMTESYELLLEKSRHEITSALISCTDHKERIEHEIASLEQDVANFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIM1</accession>
    <name>A0A8K1CIM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc-ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIM1"/>
    <dbReference type="OrthoDB" id="126967at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="Zn_Ribbon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc-ribbon" evidence="2">
        <location>
            <begin position="758"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="830" mass="94182" checksum="03A8A9CC8D9FB1AC" modified="2022-08-03" version="1">MDAENDKNEANEEVSGRVKNLRSMFERSSSDSTPQWKKKTPEEKAKAARAIAKPQYVGSLEGEALRRQREMREAERKAQQDAFNGFKRNHYAVEHDSSRQLKERQERLKKAEEDAKQGMTRVTMTTTLRDASAEIMKQRQAEERRIAQLHREIHSKPSMVAVEHDSVRQLRELQEKVKKAEEAARQGMTRVTMTTTMRDATAEIQKQRQAEERRIAQAHREIHSKPSMVAVEHDSVRQLRELQEKVKKAEEATKQGMTRVSVTKTMFDAAADLQKQRQAEDRRIAEATREIHSKPSLKAVEHEAVTQSRELQKKVKKAEEETRQSLSRVNVTKTMLDAGAELQKQRQAEDRRIAEATREIHLKLSSKAVEHEAVAQRREAHEKVKKAEEETRQSLSRVNVTKTMLDAGAELQKQRQAEDRRIAEATREIHSKPSMKAVEHEAVAQRREAHEKVKKAEEATKQGLSRVSTSKTMFDAAADLQKQRQAEDRRIAEATREIHSKPQNNVEHHSADVKRARANSLRQAEEEAIEARRRVSGAKTMVDAVSDKEKQRKEEERRIAQEHRDLYARTSSFTGSDLATEDDSSAYQDTEGPSSNQTAEDLSLEQDKEEASSESVAETPLEQVADESSPEQVTELSAPEQVKEDATPKQVEEESTPEQVKEESAPEQVKEESTPEQVKEEPTVEHVVEESTPEQEPSPEQESSPEQDKEESTVEPVNEKLSVEEDQGETSPEEAKEESTPDQTAEESAVVETKPAGFCSECSTQNPDIARFCRTCGNSLVEMEAFEEDFSPVEFKDKSLEYDHEHPIVEPNSEELQSNVTAQPAFAMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIW6</accession>
    <name>A0A8K1CIW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIW6"/>
    <dbReference type="OrthoDB" id="5872154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="271"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="653" mass="71923" checksum="F3EA6FB02F17D0D6" modified="2022-08-03" version="1">MSYENASELSRESTGALRWPADVDLDVWYQAERAEVDDVIKDALDLSVWSLEARKDTTSIYLHCKNNEKLSYSVRVVARVAGTVTSVMDCLRSADSASLRAFMKLFHPKAYLDSEVLHNHVANNNESESLTLKWLALASGKTALGRSKEFCVREYCTVIPNHRAYGTVGVCKFESYDGVGARYAIRAKPDTYSLTVYEPSSFVIYQTGEEGMLNVTLTFSMRKARGSDSVSPGVKSLAMRMAMDMVYLQRAVQHLLFQPSTLVKKKEWVSDNERSNCSLCVQSFGMLKRRHHCRVCGEVVCASCTVFKVVSNNDQEPSRIRVCKACLGKSTAPESAQANVTVPPPPAPNTGTFNSNRSVNQLQHQSSTAASYSHGTTPPFKNITLSQVSTSSSTASDDSRRSGDEGDSIASMPQGMLPPYKSQSASPPLSSLYSKSTSSSYSDYDTNPAASVHGSVQGSPRSSNQSTATVGSSSLQRSGSKTDKRTNYFNEDFAEICMLAMETLNCAMAGIRTDDLELVNYIDGQQYPDLPRSLPTFRRIAARGKPCIVLDVSADKRIAGDKRNTAKLQFFVGIPLIMDGEVIGDLCVADRFPRESIDYKAVEVLIVLGKTVTQYMTSRDFMEDLAYFKALQRKKREQEEGIVSNAAMKEVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIY9</accession>
    <name>A0A8K1CIY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIY9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="37646" checksum="928E80CA3BD089A0" modified="2022-08-03" version="1">MLPHANAAAFASPIPVTSVCAPCMPDCLASNTFEVRSMLRWRPTQLTFVSMFDDEVELYYGPSSDRTTMVRIKRSATEPNAIRLKEKPTKCEFSLTIPKRLTKLRLRAASPREYALWVHVIRAALGGPSITVQSIRALEAKATPGYASVFMHHLARVPTQASSVATAAESSPSPSPPSTSSTSSTSSVRTPVGPIDPIDPVDPVDPVDPVDPVDPVEGLDLASLVSPLRSPLSWSVTPLTPSSSSSSSPRSSLLSSRSRSSSVSSLLSSLLTTSPIASSRGSFEFPELHVELDVELNVEVDSPTSSAGSCDWDQELEYALATYQTTIENARYYEPLHHKASRVSLYTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ46</accession>
    <name>A0A8K1CJ46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ46"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="37"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="17442" checksum="3BECE4ACDEEE21DF" modified="2022-08-03" version="1">MSETLGPKLAPFTPSGDGVLAHALDLLQLTADDVLFDLGCGDARMLVHAAMHTHARCVGVEYDEQLVSKALTRVQDNAVAERVTILHADATTVDVARATAMFLYLVPQGIKLMLPKLEEAREHGVRIVTYVFSIPGWRVDAVRDFKGTKVYLYNSPQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ69</accession>
    <name>A0A8K1CJ69_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052603">
        <property type="entry name" value="EFCB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20875:SF2">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20875">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="581"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="854"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="883"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1158"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1561"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1710"/>
            <end position="1745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1238"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1388"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1635"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1783"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1918"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1242"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1257"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1272"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1390"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1783"/>
            <end position="1792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1952" mass="219543" checksum="753DEDE196A33366" modified="2022-08-03" version="1">MVRSPSGRARGTSEDRTNNDGEDDDDDEEYQHNLTFDGVKVGPYMICKHSDDLLGHHARQVFRAKAASMRGENSIYYYLKDLMKKFGAHNHKKGLTSEQLVLDAHEFRKLVASDPAFQCAIPEDQVDALFHRIEHDDHKVIRHIDFVEFCLLDHNQLRLLLYKFRKCLKRMRLSDNEITDTFKRLTSNGSATISHELLHAAITRELDVVLTTGELYFMTRLMDFDEDGVVKVNDFEMLVKDDRASYNLVHPVQENAVVDLKITVNDAEEVTLKRDSYVQMYPPLQQEASTKMHLWYKTAPREDGKSAITNIRYAPTARDTDLVSKGFTCLQQDVNRSGAFGKHKYVWLSYVPPGTQHISEVIGLSLSSGELDDQKDARLWLPMHRGFKLVHGNLNEKSSKHGVFLWIRRRTMLDGEGLVDSQVPESPRTRTKIRMHVDELEDQVRRALRRKCPVDQDGALNFSRLFEEFDHKKTRAIGKQATLVGLGSFGIKMNTKDFSLIWERMNPPEKKSIDVLAFSMFLEMTDADIDELVSGIQRSMIRSSQQMPNYRTVFQSYNSLGDGRFSRSDFQRLFATIQVVLTNSELSRVIQRFDTNKDGVVDYSDFLRFITGVCDASTRRAQRIADAAEELKTWALERQNKKLAKDGNIDSTAAWKLLRPKRGIVEVGSIDHILRQRNLRLSPAHLKLLKVVMAPATNGEVNQASFHAFVNHLPRKITSMVYDMKKVLGAAPNNGDQDTVFDRLNVEGNGKLSLITFLREVNGLASEKTVTPFDLKDFVYLVQWAGADCGGDGAVVIDRFLAVIRENKERRNMKHEFVTHYDSPRFVEGVKLLREEIRRCAKTPDGKFNYMVPFRQFDKDHSGQILLSEFELAVRELGVDKYLSDQEIKSLMRRFDLNASGGVNFEEFLRFNVADSSAPPKPGAFADVRHVLHDIILNEQLTPLKAQAYCTSLKRMFAIIDKDTHGVIPCDRFVQTLRDMGITPPTEDLEALVVAFAGDSEDEIRYGEFCGALQHLCEHDESERSLHPPPVELMDLIQSIFLEYQDAKRKYAELGKPHVTAFQAFGITDEEHLCVAISPDEIKEVLWATGVRHPYLREELESILKCFEAQPMMFNVIAFCRFMEEGPSVFFQENTGVLDGYIARLQEDIRSYLSSGKDAEERLLHCFAEFDEDGNGSISSDEFLKVLQKAGLRHFLAPDDESLLLRFLDIDGDGVIAFNDFVEFARHADQRLVATVAHSDDLPPPSPSPPGSPPKSPAKSATSPVKSTKSQPGPPNARPSPSPSSPRPSDAAPLMSLIGRLNRKLQAPFPFDKYFKKYQVNGREPIVKARVFGKIVDKFLARLIENRIPYDMQVMDPDSLTRAYAARSDCAAVNFEIFLMDLKKSQTTKSGWSSDSSDSSEGDLSCSSDEGESGRKSGKAAPSLMKEVIKRYYKTAKDQEAFRAKLKDCIPKMEKYKKDKASDKKVYKILVLLGLRMHKTEVQPLMSYLASSSNGKVSYDTVKLGTLLNEQLTVLLGAEKKPEPPPAVPALKKETPVLSAALADKIYRCFLSAAQRNISGRKLLEKCDTQRTGQITIQDFQTVMRLMGCSLSDGEMTEIKSCLGNEKTPGSINYKMMVQQLAKQQKSGIALAKQPTTGAATERSHDRPMQLHRPTPIQVPPQEKIVSVKAPPAQTVTTEQPRGTMSSDECKRLDKVIRPFFDELLRSRTFDSKTIRSAFELYDIRCSGFVTADGFHAVLRKLDISLPDDIKTAVVSRFMSPASDRVDYVEFCSMVIPSISRRTSTSMDTQRSTLEDGSRALSAPIAQEATRSAPLSERPSMHLSLPSLGYEAHSKAIDTRSAVPPVLPTASREGWSCPVCFHTQTKATGTCEICAAQNPASVQYEMLLQCNACAFRNRSTASHCELCRLPLPEILELHGEKPKPTPSSRAVAPSSPKKLSVTASSYDEGWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA5</accession>
    <name>A0A8K1CJA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coilin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJA5"/>
    <dbReference type="OrthoDB" id="74813at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024822">
        <property type="entry name" value="Coilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031722">
        <property type="entry name" value="Coilin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197:SF0">
        <property type="entry name" value="COILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197">
        <property type="entry name" value="COILIN P80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15862">
        <property type="entry name" value="Coilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coilin N-terminal" evidence="2">
        <location>
            <begin position="34"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="528" mass="57675" checksum="86ED7CDB0ABC8098" modified="2022-08-03" version="1">MAMGWQMTPSLANGGGYGGALDPAAALMGVHPQIRVRLVFVEEVAAFVMRKRGFGSCWFLLPRNLRLVGDLMHEILDEFELGECCPDGLVLLLDGFHVLPNQEIGVLRDHDVIAVQCAPVESGVTRANDKKNTSKTSKKKRKLADTEKKSVEEGEKKPKKTKKSSDRLENASPVVKMKVKAKNAQPEQPIHAPLPKPVADTSSSDSESSSSSSSSSSSDSEGSGSEEDVSPSVKTPTRKAPAKDAKEISKDDTNARTRRRRRPRRRPKVDPTGKTPAVAPSATPALKAAPVPAEKHVEATQAPLRPLRIRGLPPSSAKPDTRNHFRFDVNSTIPDKSIVQIERAVPPQLRKYGPPAANSRRETQNGNHHSSNERHNGNSDEPVKPKAKSVDMWKRPYEIIASIADSNDPAAAKMPDMSELLAAYPAKPLDTKSLPTSAGLQADDVVAYKTVTLCMETWQPIVSEWQCGRVTSVDESEQVVAFDLYMLKRNGPSLRWQPVHQESTSVSLGELSEVRYLQGPTHQAVANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKA8</accession>
    <name>A0A8K1CKA8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKA8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="14723" checksum="5DDDD851A961A7C6" modified="2022-08-03" version="1">MGLCQGKPATVSRKTSTATTTTMSSSQRAHSSATQNKAKPQKNTTYSSNTATKSATKKTTTRSSGGSSKPSYSSDTYSSTAVYSNPYTCGNMGGYSSYTDNTSSSSGHHSSHHCHSSSDTGGYSGGGSGGYSGGDSGGCSGGDSGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKM4</accession>
    <name>A0A8K1CKM4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKM4"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="213"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="37146" checksum="A37E82A4D1B91948" modified="2022-08-03" version="1">MRIFRRFPSQHGDFVHDLSFDFYGTRLATCSSDRKIKIWEEIAGEWKPQCEWNAHQASVWKIAWAHPEFGQILASCSFDRTVSIWEDQGLPLNGGVQASSVPASRETWRNQAQLVDSRESVHDVKFAPRHLGLRLATASEDGFVRMYEAIDVMNLSHWPLQEEFLADKEGVTCISWNQSRFEAPMIVVGGNSDVVKVWGYNNSYRRWQVVAELQGHTDAIHDVCWAPNMGRSYHLVATASKDRTVRIWKLKMQDTLQCDVEEVALKHHHDSEVWRVEWNITGTMLASSGDDGTVRLWKSDAEGNWVCVNTICGDLGVLSPIDLKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL66</accession>
    <name>A0A8K1CL66_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008139</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL66"/>
    <dbReference type="OrthoDB" id="163492at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="369"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="889"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="895"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="914"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="967" mass="107417" checksum="285184BAB5255355" modified="2022-08-03" version="1">MARQDASKAWERALHGSQTGNAPIMPLHAVENEVDARHYGRTLAKLVFNPAQWKRLPLQSTDSVDVYEIVDDAVSSAKKAYVPTGGPRPVRCVRAIRTVRGSLDDVVDVLSATYRSQLFARLVPHLYASGGCVSDYGVLTHPTGEQEFTNVQFAMHQPQTMIRKSGTRPLDHQLFLEYTLTTQLQRTREEESEEGTTSTTTSAVPSVLYVLRPVLIPAFSARHAEYEANRVTRNDFTVTYVVQQTEDDHELSVEVVVTCALAHTEFVGAQALVREVVALSALQELINRAREAKGVMGLRVGSNQNDLERPSTRMKVKEFFSRDRSRTRTKKPLFKSRTPSRDAVAMAYDLTDDDDTASIASSSASSNMSANATGCAICEKRFHAFRWKKRCEMCQLFVCDHCLSTIANLASMRSKKRVCKACIYGNNANHDAVTRSAAHAEPVASRASGRMRAATDAVPKRMNEPIGRPSARRFTTVDPMAAPSRMAARPSQSKYRHVAKSLSTPIESSVPEDAIESGSAEGYSFFDATEPSGVVSDDEFIVNGASRSRRAKTLQARGSTTTGRARASTKVSARESASRPRGRSFTNDHEAPVINGKELLKRLTTSAPKPVKSQVALSTSRGSSRVRQLKTPPVEYELDFNWLQPFPKTPAPVDANRERERVNWLESQLKLDAQTAMMNLRRDPALEELTQKIIRSVATQWDGCGVNFIDDKQVVCLAYCYKENVRLDELAIATISEDLLPRAESASAYALYHKSAFFVADLQEDVRLNAHPLHTDGRVRSYLSLPIFATQGRRSCIGTLDLWKFDPSEPMNSQVSQDWWLALEKAVTDVAEHIEEISTTQGCRPSLVKPVQPFMKQPRSIGSSGDSRSSTFLADSLDLDSLDLEEPSSYMDGRSSWTVGQNDTTFMPQRPRRHTDADQPQHFEPHSYGSSAGRSSTSSIESTLETLLERIRRTSEIIEEQNALHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC2</accession>
    <name>A0A8K1CLC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC2"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453788" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="420"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="745" mass="83021" checksum="EB532F3F46F5487C" modified="2022-08-03" version="1">MFRWAWVIFLVFHALWGPAATAQSLLEADEFIVTDVRVVEGRTEVEAREKCAALCPCSSLLSQHVVSNWRIVGSNLNSASDSGSSGAEASFVYLCVKQDRFALVHRDPTTFFAAQAVHVIEDSMCPSSLRLLYQPRPGVVICLAVIPAPVAFATGMYISEITTVVNPTDVQDSSGWTTLTTSIETEPRISRGSTTRPASLVYLSYKRPRRPISDVRVLADVAKTDMWKACWSTLGPAWEQAGSGYIKLPSIDTSTIVCVQRPQVPVIELAQAATLINQVLVAVRVFKTGEACPDGFQAKDVLSNSWVLCLKYDESSAKTFISSLSLTSAGGRFSNNQDHAGLHSALTLSTPDKFASTEDLNEARGGVSSFLIFREYQPRQKKTTKAPRSKSTPEPSGAKPPLMAKFTPTIGSDNSGRLSFKVLQLADLHFTGDRDWPCKGPPTELLQCGLRCSEDLTESFVHDILDKENPDFVVFSGDAIQVRDPRLRDAAIEAALRPVESRTIPYAVIMGNHDDDYGFEREEIISRIAGRKLSYTERGPKSIFGVGNYVLDIKAPAEGPWGANGTKVFRMYLLDSNKRPDRIKFPTVNSNYDWIRPDQIEFYRQHSLANRPPEGPLPAIMFFHIPFPEYNVYFRHNGDKNEAIEGPGYNSHLFDTLVELQEVKATFVGHDHVNEYCAERSGIQLCYGGGTGFGEAYGRSYIARRARVIEWSVDTQNRRRITSWKRHFGTNFHRRQLQEVLYSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLQ0</accession>
    <name>A0A8K1CLQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLQ0"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426004" description="Peptidase S1 domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="257"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="53930" checksum="5C9AE85668888FA8" modified="2022-08-03" version="1">MTVFSFVSAVLLLLDTLCAASAALPLMALGSESNPHACVGIQISLHHVLVHSTCATSSGPLTKAQVLEPPDESSADESTRVTFKSSVRVANSSAIPINQLPSDVSSSIESVHVVAFEDPLPSTISRPVTLPLKTPYPSYLSIDKNATMVSIDMATLHVQSISRITFIEGSSCNHPVCALPLQVEDQGVFMEPNRWSFLLTQSSDGDSYRLLGVGGGPATNHDGIWGFEWLPQALTTSSLSSHQVHGVQTVVSVSKEIYGGKDVKTTSEYTEFIAGLRAFKNGTTLCAGALIAQTWVLTAAGCTTYDLRYVVIDTLSTRGEPTEVLRIQQMIAHPAHSGHKYNFMLVQLDSPSRRRPVKYNQNKDHTPVSSMATAFGYGATSYHSHKLNDRLRSNKVEVLGAEYCPKSMKNRMNEATMCVKQKLCYGDFGGPVVTDAWSSDRVLYGIISNDFGCFDGSYYNVVGRVSRIADWIKTIMVMAQSGVRLTASQIANSTSATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLT4</accession>
    <name>A0A8K1CLT4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLT4"/>
    <dbReference type="OrthoDB" id="118338at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15810" checksum="6080DEFAB484C395" modified="2022-08-03" version="1">METAATKRVRWSTVTVYEFGVTLGGSAVPRRGGPSIGLARKANSVWSATVDDIEYETCSSDDSDDVLELGVSEETELQCGKSRRHASRRRRVRWLKPQERVQLLTKAGCSEKRIYRMMMESSEIAMSRRLCVAIQREIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLZ5</accession>
    <name>A0A8K1CLZ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLZ5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050938">
        <property type="entry name" value="Collagen_Structural_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456:SF3">
        <property type="entry name" value="COLLAGEN ALPHA-1(XXV) CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456">
        <property type="entry name" value="SI:CH211-266K2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="447" mass="38478" checksum="F8E95E494F868FD9" modified="2022-08-03" version="1">MSTSVSDGGDELAADPEADPGGDELGAGRPLGADSPLSTGGVLGGSGVTGVTGVVGLLSTGGVLGGSGVTGVTGVVGPLSTGGVLGGSGVTGVTGVVGPLSTVGVLGGSGVTGVTGVVVGPLSTGGVLGGSGVTGVTGVVGPLSTGGVLGGSGVTGVTGVVGLLSTGGVLGGSGVTGVTGVVGPLSTVGVLGGSGVTGVTGVVGLLSTGGVLGGSGVTGVTGVVGPLSTGGVLGGSGVTGVTGVVGLLSTGGVLGGSGVTDVTGVVGPLSTVGVLGGSGVTGVTGVVGPLSTGGVLGGSGVTGVTGVVGLLSTGGVLGGSGVTGVTGVVGLLSTVGVLGGSGVTGVTGVVGPLSTGGVLGGSGVTGVTGVVGSSFTGGLLDGVTGVVGSSLIGGLLADGSGVVLDDGGWESLVDGSGGGLLLGSEAGLLFGSGGGLGGDVVSGGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM50</accession>
    <name>A0A8K1CM50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM50"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21722" checksum="A0919245D17F2D6F" modified="2022-08-03" version="1">MYDSQALLRVSTDPRALTVLAGVIIAATLGHWTSEKLAKARDDSQVNLRHVPMPASTLPLLGNLVDVVQHAHVYHDWVLQYCRAFQFAPWKYRMALNKEVIVLAFPEAIEDVMVRHFSDFPKGERQNYLTEPIFSDGVLGSDGEKWLHQRKIAAKFFTAKTLRVLMSRSVQKGLLEVQQVLAKHQASGEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMM4</accession>
    <name>A0A8K1CMM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMM4"/>
    <dbReference type="OrthoDB" id="9992527at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF3">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="13"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="331" mass="35198" checksum="A0159F6AA041B463" modified="2022-08-03" version="1">MPSYRTVHVVKHSTDFRAATEIVEVPELPTASAGHVVVKNHYVGVNATDINVTNGHYGASQLPHGCGFEAVGEIISVGEGVENFAVGDAVAYQKMLGAFTEYAEAEVSYLIKLPSPEPWALPLMICGVSASIALYETGQMKSNETVLVTSAAGGTGLIAVQLAKLAGNHVIGTCSSDEKVQVLKDLGCDRVINYTKESIREVLETEYPNGIDLVFETVGGETMEAAIRNIAIHGRVIAFGHISAYKSGGADRLPVPGGVLGPRSASIRGFFLANHVAQAPEHIRRLVGLIQEGKLKPAVDPTPFHGLEGIADAIDYMYARKNIGKLVIKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNC5</accession>
    <name>A0A8K1CNC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008407</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNC5"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="128" mass="15243" checksum="243634D026007CEE" modified="2022-08-03" version="1">MSLLVRNLDPNTTEEEIKRAFSRRNGDIRDVYIPKEFGGKQPRGFAFIEFADSQEAREIKYAMDRTKLNGREIAVLFAQQKRKTPDQMRDQMSQESEKRERRSPRRSRSGSDQHRDRHRREERETSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CND5</accession>
    <name>A0A8K1CND5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MYND-type zinc finger protein samB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013981</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CND5"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="4"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="62"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51391" checksum="0316085D0C9997D9" modified="2022-08-03" version="1">MADETMASVRFHGADGGVEDTSGDRGRSVMLTTIQAAHPGALVFKAPVFAKILEPSLWATHCHHCFRAKHDAVTAETTGLSRCGRCRAVYYCSRACQQQDWRPDHQLECTRLPQLTTLRLRSDQIADILLLGRVFRRLESSEKGSESPSPLDFVWNQADLCQETELLSMLASKLGLVDAKWPLDAIQKMLSRFQNNNYSICDAKFLPLGSGCFPLGAMVNHSCAPNTVATFRRDSLAMEFRALRVIEPGEEITHSYVDPIVPRTQRQARLRGRYHFDCQCQRCVGSENDAEGRRDQYLDADVDGIPQSRWPAKRQEALQEAESKSEDPEAWDTLNRRIETLRGILNVQQRHLHSENTQLLGTLSQLFEAQLEDEATRSDALIMGEKILHVYERVYPENHPMIGLQRFTLGDLCITLSRLASAKTYFSDAYRILQITHGRKHELVELLRRRLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP22</accession>
    <name>A0A8K1CP22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_008440</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP22"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442217" description="ER membrane protein complex subunit 1" evidence="11">
        <location>
            <begin position="18"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="13">
        <location>
            <begin position="18"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="759"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW65798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="977" mass="106675" checksum="1624EEF49D5BE76D" modified="2022-08-03" version="1">MIKSLAVLLLLVQSVQGIYEDQAGEFDWSVQNLGRVVAVAYGGGDKRSAATSARGSGRAVYVASDSRSRALARLDAKTGAIKWRNVLYADDAVDAIELTNYGLLSLSGGGKNVRMWDAVDGSLVWDNVVFGADKSSSTGDVVPIGDDRAVVLSLNTAVFMNLKDGRVSWRAELPAATSAIESSVVSSDGSALFVLVQSAGKHQVLSLDVASGGVTPVAVDEKSEAVVVRKSEKGEAVFVVVSASEIKIQSLESSSKSKTTLIGDLALPASKTTQRFAGVEAEVKNGLTIRLASGKRVYCSISDSFELKAASVLSEDGVVVESSTEDAKLFHVTASTQKQVQVASYSHNAQTSRTQWEAEVDVNLHGGAVSSAFAACPTRKKDSGAPRCRVLLVMRDDGLIMTTNEEPSDSEVSVETAKNVLWTREESLANVKETLWITPAETQIEKQPLKGIPSFVEDLQLDIERLQQFVQHAMSMSSSLFEPKSAGDHKARKEPENAHFFGFSKYLLALTESGRLFAIRAETNTVAWSSFVGPAYRLFVLRDHPVLGSGAELLLVSNSTQLSWVDGDDGRQIESVDASSNSNAWVVILPKRKHHIDEDTTIRRAVAVVSKDSLDVSIFPEEAASVGHPEAENFYFYRYDESIGAFHGYTIDKVGDKGYKARQVWSVVVPSDQKLVATSRQRENAVIDSSVTITGDDSLLLKYLNPHMFGLTTLSHEKLEGSHKTTPVLHVSLVDSVTGRLIHRVRHVHGSEPVQMVQSEHWVVYTYWNSKDKRTELVSLSLYDGAVGTHSLNLWKRPSWNEVRSSYDPRAPFVLQKSFVFPAKISTLGVTVTSRGITPQYVLVGMENGQVFKLSRALINPRQPEKPPTPEEQNEGLGQYSPLIPLHHNLYSMVTYNQTVANLKAISTTPVELESTTLMVAHGLDMFYVRMAPAKAFDVLPPDFNYELLVLLCLGFLGAAYVAKGFAQRKALNEAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQG4</accession>
    <name>A0A8K1CQG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQG4"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="6">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="120" mass="13547" checksum="638F56478F3F5C03" modified="2022-08-03" version="1">MAPLNTSSPTNADCIESPWTRDGTYIIECTRRAHACCRSCDSTIEVDRLRMGVVYQHKNGFVCINWHHLECYPIVQSIPLCNLEGYTELDASSQQLVRHCLLSPEVEDARFRQTPSACTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC5</accession>
    <name>A0A8K1CRC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_007856</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC5"/>
    <dbReference type="OrthoDB" id="94354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="17">
        <location>
            <begin position="44"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW68184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="53866" checksum="7C09EE06225474FE" modified="2022-08-03" version="1">MALPLSPSPAIPSFYVPVVTPKAQETPTTIRVNALVYTSAALALLQSAQFGWSLSQLNLSTFNDKDDCDSRPVAAGTCLMFPGHSKTEWTLAVNAWTVGGIVGSLICGSLSDAFGRRRTWFVSCALMIAGATIQAASMSLPVFVVGRFVAGLASGFATAMCNGYINDVAPPHLRSMLGSCYGLSTATGIVLVGVSFFFANTASGWRYIAGFPIVIAGVFLLLAPRYLAESPSWLLAKGRREEAEAEIARLFGWENAATALTWMETTPTTTADESSTSKPSERSTAELESHAQRSSPPPWKALISTKYRRQTLLALSMSVALQFSGINVVFFYSSSMFKDAGVEDDRVGSLIVNMVNLLPSFVVGVLARRFGNRKMIIAGQVGMLLSAVGLTIALLINVQALSIVFMSTYVAGFSLSLGPLAFAVASDLFPDALRANGIALTLFVNWCGTFVIGVGYPYIADVLDDLAFLPFIAVLSFFVFFMTKKLPETSGKTSVEIQGLFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH3</accession>
    <name>A0A8K1CRH3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRH3"/>
    <dbReference type="OrthoDB" id="124765at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="417" mass="48060" checksum="75C4C7C874FD1943" modified="2022-08-03" version="1">MTTDMETDTLAAVLAYLEGYSDPDEVVGLSSSDDTTAVSSRDSSDDVQRQSSRRVTKKDVAHNRARYRKRLELEALRQEEVNLRERLEKLTHARQVRLEGESSRSNSQRRDMLTVWRDVTKRQFQRRQAVEEENVRLKSRLLEQRHVVKTLKRIIEQQVRKANPPLASARLYSPAWRAVCGDGDPLRMMRVFGELVADLKHIHSTTDDWIQKSTSRPLIDGRFLESRVVPLSPTQLAVEITDLRLLPFPYEVVGDVYWTKAINKRCTVYDFFRETSQVEGRYTIFNGKAFDDDHDTSRLAGVRLRSHLTSQKFVDPDRIVLTNASRTDSVLVEREEVPGVQLTEQYWNVFRPLDSSTRDACLLLSFGYVLITVESGIDKAPRAVPILTRYFEKRMHDHIGINVGIVEDWLLQSSALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS44</accession>
    <name>A0A8K1CS44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS44"/>
    <dbReference type="OrthoDB" id="186013at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="76" mass="8202" checksum="C21EA5E998062A81" modified="2022-08-03" version="1">MLFAAVKNLPKTQAIVGTISGVFALSYVCWAADRYSGKDYGGAAPGEPHTTSAEWQAASVEYAKAQKANPIRHFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSB0</accession>
    <name>A0A8K1CSB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSB0"/>
    <dbReference type="OrthoDB" id="434723at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039491">
        <property type="entry name" value="REX1-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28309">
        <property type="entry name" value="REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28309:SF1">
        <property type="entry name" value="REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14966">
        <property type="entry name" value="DNA_repr_REX1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="201" mass="22639" checksum="FA55BF8E46CFA817" modified="2022-08-03" version="1">MDLQACYELLAQRPAHAHAHCEGEHSHEAAEQAVNEVAAAVEASLRLGDDQVSVAALGRAFFEVQELRVHIYGEFQKGFEQFKATPQFQPFCTQITEQFAQVSQQVNAIETLLREKQRVALADLIRKVQGQEKEKLLLTSALAVERMRVTDMLTRPEPDAAILSLLEQSVAKMTAQHTEIIVTINELLDELRMELVDEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSD3</accession>
    <name>A0A8K1CSD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSD3"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000295">
        <property type="entry name" value="Glutathione S-transferase unclassified 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051369">
        <property type="entry name" value="GST_Theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917:SF8">
        <property type="entry name" value="GH16740P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25385" checksum="59ABD3D3FE7EA7EA" modified="2022-08-03" version="1">MALKLYANLVSQPSRAVYWLLKVKNVDFEHVRMDLGSPVYQSPEFLALNPSGLVPVIKDDDFSVYESNAILTYLADKFDWEELYPKDLKARAKVNQYLHWHHTGARNFTLQVVRPVFRKALGKASPEDLVAVEKAPEVIEKHTSIVEKMLVNDYVSETVQPTVADYALYCEYDQLEALGLLDLGKFPKTAAWIERMKKIPFHDEVRLEMNGTFAAIGLAKKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSM8</accession>
    <name>A0A8K1CSM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSM8"/>
    <dbReference type="OrthoDB" id="148713at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="40962" checksum="AD1BA32A2BDE7790" modified="2022-08-03" version="1">MVTTDYKLFTPLPIGKDLVLKNRVVMGPMGRARTDKDSRAPNDLNVQYYGERAGAGLIVSEATPVSSQGYGWLGSPALYTQEHAAGWKKVVDRVHANGGKIFLQIWHMGRQAHSSFSPEAPEVVSASAIGITSGHTRNNKGEEVPYEVPRALETAEIAGIIDDYRKSATLAKQVGFDGVEIHGGNGYLVDQFLQSATNKRTDQYGGSIENRARFLLELIEALKTVWPSDRIAVRLSPNGAFAGMGSEDNVETFIYVLQQLSQLDLAYVAILDGFGFGYHDKAPLMTAYDIKSHYKGTVIAANSYTRDIAEGAIRSGAADAVCFARPYISNPDLAERFQNDWPLNPDASYADFWDSSRGAEGYTTFPAYATPKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT68</accession>
    <name>A0A8K1CT68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT68"/>
    <dbReference type="OrthoDB" id="192262at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="39539" checksum="D5C0C263322EB678" modified="2022-08-03" version="1">MELRFDEPSFCWAKSHENTAPEQSTQPQGYAVRAVLPTLKHDSNEREFETIMLPGVMTIPVEDESEIFKRTAVFHVLLDGQEIGQHEVSMRDCIPILSDATVEWQQTTNSNNHNAGSVVVKIRTSTNREPREKIQRYMNYQKKAASLTRSLALHKNAVAVGLLPPIIGCVVGIVATSPFWLPLMLLIGFVGFPVWVIVAVAATLLIAISAVSTVVAVSLAKSKRVKKTAKEICQSSGGQFILFDNSGHGPSTGEIVERTMEYINGDPARKLLVSLVIDFIGSSTFVLPVVGELADLVWAPASAGLISAMYHKTSPKFKYLAFIEEFLPFTDFIPTATIAWMKENLSLKEITNVLGKLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT86</accession>
    <name>A0A8K1CT86_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007873</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT86"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046354">
        <property type="term" value="P:mannan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="497" mass="57517" checksum="9D03E1818C638E85" modified="2022-08-03" version="1">MAVLTTLMGCFVSCFVTLWLWIRFQDRVSVVVPWGKTEEQCWAPYPETPWDVDEFECLEWVATDEDGTPTGETRECWQRVRGGEAGFCRIRNVSSANIFHVMHTTRLSLKDEVRFTCGLAKAFTEFRHLAKDYTHDPPMLLPQGELESIGIVMAVYDQVLASAYASIRQLRSTGCQLPIELWFRHDELKKENTVIHQLMTLFGPIKLRVIHDDRIRGFYVKVHAVYYSSFTSVLLLDADNFVVQSPTPLFSSATFQAHGAVFWPDFWHPGNTIFNIHAQSLLWELLGIEYVDMMEQESGQVLINRQKSRVALEKLMFLATNHPNLLRKLKLVWGDKDLFRLAWFLARKTFYFNDRRVPGALGVINHDRQRFCGMSMVQYDLDGQSILFVHRNTIKLTGQTTEKRIWHTLQEYEPGVKPVIHSFNGDKLFNETSCFGVKRFQFPEQHSTVRMRSVFQVPLLRHLEDKLSLYAAEASLMVHNRGNPSYAWPITPRPCDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTW5</accession>
    <name>A0A8K1CTW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTW5"/>
    <dbReference type="OrthoDB" id="10257948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02989">
        <property type="entry name" value="Phd_like_TxnDC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="73"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="233" mass="26833" checksum="9A8FF9A7B6117D52" modified="2022-08-03" version="1">MNAEVVANIIGERVLETLEEQEAQLDEQIKRLEEADDDELERIRERRLQQMRQQAMKAQEMRAQGHGEYSTITDTKEFFETIKKSERAIVHFFTPSNEFCQLVDGHLQRLAPHHIETKFARINAEKAEFLVEKLGVWMIPCIALIKNQKVVKMVQGLDDLGGTDRFTTAFLAYYIGLHEVIKYEGPEPESSLDDCGGAYMRNNGPTGQQEQSRQQSSIRQTVYYDSDLSEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU71</accession>
    <name>A0A8K1CU71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulose 1,4-beta-cellobiosidase (non-reducing end)</fullName>
            <ecNumber evidence="3">3.2.1.91</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.91" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU71"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016162">
        <property type="term" value="F:cellulose 1,4-beta-cellobiosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.100.10:FF:000001">
        <property type="entry name" value="Glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456074" description="cellulose 1,4-beta-cellobiosidase (non-reducing end)" evidence="10">
        <location>
            <begin position="21"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="50090" checksum="60BF8560F4A6DD01" modified="2022-08-03" version="1">MQLASILAFQSLALASIASAQQIGQSEPEVHPSLASQQCSLSGGCTTESTKIVLDANWRWLHKVGDYKNCYSGNQWDTTLCPDPETCAKNCALEGAKYADTYGITTSSDALRLKFVTKGQYGTNVGSRVYLMQDDQQYKHFKLLNQEFAFDVDVSQLPCGLNGALYFVQMDQDGGKAKHPSNQAGAAYGTGYCDAQCPHDLKFIQGEANVLNWSASASDANSGGGKYGSCCAEMDIWEANKMSTAYTSHPCSVDGLYRCSSPEECGDGALRYKGVCDKDGCDFNPFRMNNKQFYGPGASFALDSTKPFTVVTQFLTDDQTANGKLAEIKRFYKQDGKTIENPAMNWTGADPLASITDKMCKQTKTLFKDEDDHARKGSLEKMGEALKSGVVLTISLWADFAANCLWLDSTYPADKSPSIPGVMRGTCPTTGGKPHELQEQVPDATVTFRNIRVGDIGSTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUD2</accession>
    <name>A0A8K1CUD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUD2"/>
    <dbReference type="OrthoDB" id="164025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052289">
        <property type="entry name" value="Calcyclin-binding_UBL-bridge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164">
        <property type="entry name" value="CALICYLIN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164:SF6">
        <property type="entry name" value="CS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="103"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="214" mass="23917" checksum="0A63C4EF6BF70B1C" modified="2022-08-03" version="1">MPSAHASYVKLVTPWGELHLEKDLLFKIAGTVAVLALTTVSYLLIGLWSKAKVKAGAQGQKSAAEVKRSALEENIVKKGEHSYYYAHQARSTSETKTSDHKKTMVSSYGWTDRKKSVDIYLTDDAVTDMTKEQLKLNWTPTSLSLDVVTDEEGKNTKSLVIPTLFNEISDVKWKVNNNQLTITLYKVDAVAWTSLNGAAKNLEDHIEYDDSLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVA6</accession>
    <name>A0A8K1CVA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_001759</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the JMJD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVA6"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033749">
        <property type="term" value="F:histone H4R3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106140">
        <property type="term" value="F:P-TEFb complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF32">
        <property type="entry name" value="BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="13">
        <location>
            <begin position="177"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="386"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW69603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="435" mass="50444" checksum="B214AA74BECEC189" modified="2022-08-03" version="1">MRSRSPSLTSSSSDSSSDDEAPRQTRFPYVPPPQFGDKVAKIVTDAKRKHRTDIKPHAWDREGFAGSDVCELPLDETNAIKREHARDLTVARFIQEYEKPFVPLIIEGIPETEGWGAVENWTLKKLRKNCKRAMLKCGEDDDGKSIRMKFKYFYKYLKLQTDDSPLYIFDSSFDDREDTKPLLADYAVPRYFPEDLFSLVGEDRRPPYRWFLVGPKRSGTCVHLDPLGTSAWNTLLVGRKRWVLFPPHVSKEIVKGKSHIKKGEDDEAVNYFMDILPRIKKAHSPEELQCIELMQYPGDTIFVPGGWWHAVFNVEDTVAVTQNYCSSQNFERVWRKTRTGRKRMAVKWFQKLQKHHPQLATLAVKLNREDGFVMRHKDGSAFEPEVLDEAEDQDHHTASDRESTTSSAESSMKKKKKKKKEEDENAKKRKRARME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVN3</accession>
    <name>A0A8K1CVN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVN3"/>
    <dbReference type="OrthoDB" id="159553at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436662" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="35"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="17983" checksum="AAA1E2129E718A5A" modified="2022-08-03" version="1">MQFSTLLSMVAVALTASSTQAAPPSQSIGGLNGVNCLNAHNKVRAEVGVPLLEWDENLAKKGKDWATHMEKNNFFAHNTPGQTDYQMNNLYGGTTCIDAVNAFYAEKSKLPADRVVRAESYMQYGHYTMMVWRSTTRVGCGRGPTKNVACYYETPGNMIGQAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9B2</accession>
    <name>A0A8K1F9B2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9B2"/>
    <dbReference type="OrthoDB" id="189459at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046834">
        <property type="entry name" value="ABC_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019195">
        <property type="entry name" value="ABC_ATPase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046833">
        <property type="entry name" value="ABC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049069">
        <property type="entry name" value="MRB1590-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38149">
        <property type="entry name" value="ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38149:SF1">
        <property type="entry name" value="ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09818">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20446">
        <property type="entry name" value="ABC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21117">
        <property type="entry name" value="MRB1590_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase of the ABC class N-terminal" evidence="3">
        <location>
            <begin position="61"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase of the ABC class C-terminal" evidence="2">
        <location>
            <begin position="238"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="MRB1590-like C-terminal" evidence="4">
        <location>
            <begin position="529"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="630" mass="69364" checksum="718DB9F827BFF0D9" modified="2022-08-03" version="1">MGRGEYYRNKYGGGGRGRGRGGPREERRDEYPSEGRRSGGGWRNNDGDIATSSSASVLTWQQLGNLLQDIHNRNYNAYHDLRRVFAYESRDLCFQLGFDHIQGDPYASPSRAHVQVLSASARFPREMHASKIRNVALCDYLTRQFAESARRAGADAKTRSNSWHGAKGGDMTIDAPGQHVIERSSVMVYEDGVVEARFNINLPARGRTICGDWAYTILVDTLPVLVRQALMLESLNTADVWKHLYSVEDQETLRGLLKTANLVGFARDGAVLPRESGASDRPLGKDKAVAFKSPPTLQRSFTLPNSGEITGMGIPAGVTLFVGGGFHGKTTILKALEVGVYNHIPGDGREFVVMDADAVKIRSEDSRSVVCCDISSFIDNLPFKQDTTKFTTADASGSTSQAANIIEALEVGATTLLIDEDTCATNFMIRDWKMQQLVAKDKEPITPFISKVRALYENHGVSSVLVIGGAGDYFSVADHVIMMDSYEPRDVTVEAKAIASKHGEIRQEDEFGGFRARIPLRRGFEVSGKVVSRGLDRIQYGDVDLDLGAVEQIVEPSQVRAIADAIQSAREFMDGRRTLKDVLLAMEEAMDRSSSLDTIGMHSKSGFYARPRRFELAAAINRLRSATMTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD8</accession>
    <name>A0A8K1FDD8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="48166" checksum="BC2D863453575921" modified="2022-08-03" version="1">MVLAPSLLGQLREFVLHEVQSVLQAVPRALRSLRETLVAIEEWLIDSAKCVWKTCLSGSEDESWLEYFDRLTGLACRAITADEPMLPVSRPSGRQPSIAEFEWLAVTRDEYAQRNAELRRTIIELREKMAELEGQKRVSQAEIVHLRQVVERLRELHELGYHRQAHDIAVSLQRILGAQLSAPAAQGASPNCLLEGLAAKQATSLSGGGQDELTSSHEPQLVWNSVSMAGVARLPRHDWNVHWQNNVYAPIRPPSEASEAGEDVSQSFVLEEAIQTAPRTVDGMTQTDKTSSSVDRAEDKPSSSSKPTHFARVRNATSVPTTVDSQATCDATPRPTEGLSPDVASPSSLSYRQLTQQELGGSTFYMEALRKLKEERQQRRQLRQKSTSAADVLYSSFTTCDLQQSGGKHASSPTNSSSSSTDTAESEVCPDASRCVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDE4</accession>
    <name>A0A8K1FDE4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDE4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="746" mass="84349" checksum="5A225FC47B91A8F0" modified="2022-08-03" version="1">MCFIWEFTIKICIGNMTTTQWTGTYNDLAAALANVDESDFVGMEDYHFAPPPVLVSNTQTMGSTASSDDSEETKMSGPKPEFKRRNRPRDELQNLRATVRQLETRLAILRDQSGKVPEPTQKTDAVADKMWEGIAGRQLRELDRSERENARLRTMVEDQLRTIKSLERMVMKKRSKVTSIIQQPSPSDDVRDPIHDPELDKQIEEEVITMLNDIDRIANDPRFQVSLDNPLHITEVLEDAGDGLVVESLDGRLFPFDYQDTADALWTMWKSVPIDLVHGTAPDNLRFTDSTVWRIDAGELENLGASIQFHSKLIGRRRIEDNRVVMASILLWTSTYNELAAALANVDESDFVGMDGDLFVAPPLPSSDTQTMGSTASSDGSEETATAAKISDETKPGTKRRNRPRDELQNLRATVRQLETRLAILRDQSGKVPEPTQKTDAVADKMWEGIAGRQLRELDRSERENARLRTMVEDQLRTIKSLERMVMKKRSKVTSIIQQPSPSDDVRDPIHDPELDKQIEEEVITMLNDIDRIANDPRFQVSLDNPLHITEVLEDAGDGLVVESLDGRLFPFDYQDTADALWTMWKSVPIDLVHGTAPDNLRFTDSTVWRIDAGELENLGASIQFHSKLIGRRRIEDNRVVMASILLVRPIKLDGTPLSGVHLRLRIWNIFRPINKSEATSFTSRQLYTQCTLERQDGSDGGDSLSGVSLLASFILHNSGPRLELNNQVLENQLIKRFKELQAQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDW5</accession>
    <name>A0A8K1FDW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">pectin lyase</fullName>
            <ecNumber evidence="6">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006946</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDW5"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047490">
        <property type="term" value="F:pectin lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF67">
        <property type="entry name" value="PECTIN LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469613" description="pectin lyase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="8">
        <location>
            <begin position="75"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="395" mass="41872" checksum="C31EF88BB5792C2F" modified="2022-08-03" version="1">MKFLRTGVFALVAVIVQSVADAAVPGIAVGTTGGGSAKPVYPKDIAELKSYLSDSQARVIVLNKSFDYRGSEGSKTETGCEPKSYRDCVAKNNGYKAQNVILTGTMTTTGGCDEGKATTVTYDIAGAKNPLVIGDNKTLRGEGKKGVIIGKGIWIRGNNVIVQNIHITNLNPHLVWGGDAIYLQSASNTAPQERVWVDHVKVSSVGRQMLVTNGAGTKSLTVSNCDFDGRTSYSASCDGRHYWTFYYEGKDTRVSMLNNFVHSTSGRSPKVTSAAGNSIVHIANNYWSDNSGQSSFDVYHSGYVLAEGNYFDNTANPHVATTSDSNVFVPTSSNADSCKSVIGRACVANAVTSSGKLTGTNEATALAKMKGVATYTPRAAKKLLLSSNNWGVGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDW8</accession>
    <name>A0A8K1FDW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDW8"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="233" mass="26587" checksum="D42F606A96D23C5F" modified="2022-08-03" version="1">MYVRTTSIHASRRKRSRLTASRLRRSRLLTEVAMRKLNLDPEKTERMSSISDQLSEDDINFFTHIFMQIDSDEIGIILRSELHEGLTLLGITATDKELDEYLLIADADGSKAIDLQEWIVLCAMLVKPPHEEHELLAAFNCLFPNEQDIPVVMFRTKMQRLLENAYAHLPECNHHEVSCFVDDILSALDPNNTECIDVQECIRILSTAYNSSTLPGSPTNNATSTEERDNHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF42</accession>
    <name>A0A8K1FF42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003212</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF42"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="9">
        <location>
            <begin position="34"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="231"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="506" mass="55869" checksum="67ED337C1B433105" modified="2022-08-03" version="1">MSFQPRLARIEELRNLPENANKNLVPVYLDAVADLDTPVSVLLKLREGEKYSFLFESVAPGEKIARYSFIGSGPLKVVATGEGHEYSGDPLVNLEKEMQQYRTIVLPELAVPMTGGAVGYCSFDAIRHFEPKLEPYVAKQRDVLQIPESVYMFFDTVVIFDHVFHSLKIVSHCRLDTDDLEAAYAEATHKILKVRDAIEKPLIRSSSGSHAAAAPGSGKVDVEAASNVGKAGYMGFVDKLKEHIVDGDIFQAVPSQRLAVTIPSEVSALDLYRQMRALNPSPYMFYLDLGDDFHVVGASPEMLVKVNHERVMETHPIAGTRHRGKTDEEDEALAKDLLSDEKERAEHIMLVDLGRNDVGRVAKPGSVRVDALMKIEKYSHVMHIVSVVKGILRDDKTVYDAYRAIFPAGTLSGAPKVKAMELICSLEGERRGIYGGSVGYFSFSGFLDTAIAIRTIVVKKNKVYCQAGGGIVYDSDPFDEYMETVNKLGSVVRTVEKCIAHKAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFC8</accession>
    <name>A0A8K1FFC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-binding cassette sub-family D member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007004</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFC8"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000636">
        <property type="entry name" value="ATP-binding cassette sub-family D member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="84"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="445"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="75470" checksum="6A9B8A5C514687DE" modified="2022-08-03" version="1">MTVLSKSHAVSGALSTAGLVALALAIHERGQRKAGEALREDSQFMTKKHGNKQKVAINKEFLTRFMRLFKVIVPGLVTPEVGYAFLVAGLLAARTSFDILILQIVTSIERAIISRSTEGFMHHLRRFFLVMLPVSCVNCLLKYGQTELTLRFRNRLTRHLYDLYLKGFIYYKVSNLDNRISNADQLLTVDVERFSNSVSDLYSNVSKPLLDICIYAVELTSSIGFQGPATMLGYLVFSGMFLTWLRQPTGRFTIAEQKMEGNFRFMNARLITHSEEIAFYNGNVREKRILDQSFTRLIDLVRQSQQFRFSISVIDNIVAKYFATVVGYFVVSRPFLDKEHPRHLNSSYAERMEDYFRSGKMLIKLSEAMGRLVLSGRELTRLAGFTARVTEMMDVLTDLDEGRYQRTMLKDNEEDSESSPTAKASASSLGLYPNKGEMLYEDHVIQFEDVPLVTPNGDVLVKALNVRVESGMNVVVAGPNGCGKSSLFRILGELWPLFGGKLTKPERNGLFYIPQRPYLTLGSLRDQIIYPHSHEDMIASGRTEADLLEFLEKVQLGYLVDREGGWDVVHDWADVLSGGEKQRVAMARLFYHKPQFAILDECTSAVSVDVEGAMYNHCREQNITLFTVSHRKSLWKYHEYVLRFDGRGDYQFKKIEEADEAFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFD5</accession>
    <name>A0A8K1FFD5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFD5"/>
    <dbReference type="OrthoDB" id="78308at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24110">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 78 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24110:SF3">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 78 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="431"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="56052" checksum="39CCAB8641E54C54" modified="2022-08-03" version="1">MPFSIEAYKRRVNARSAKSRKAKASTLPDENFEGFQKKYLDFCVEKTLDPDHALLKALRTSSFVLTLDGLSGEELASHLAFLQRCSELSQLMLSLGSLAVDRELRKKFDRLGLKKAPAFAKESTAKIIKAVCVACEQSPRLIRLQLKGILITEKQAQHLARTLVKCTQLESINWANSRLGDQGLAEVSVVVGKLPRLVYLNLSVCRLTEKARDHLAKIITLHGALQDESAWSSSLRSQSSVVIVDKPPSLVLDLSHNALGDATVQTLCDALYHDKWTLAIRLCHNRLTCNSYALLHKTLQQSNSTLAVIKVAEEEESNAMKAATHDLSGLAARRIGVLQRFAAESNERRLFLCHLFLEWQVERELVLRICGETGSEVDAPSVGAVSTDSKRSSHQKPKVNAWEEETQNRRSPHPEAVTFLVGRLAVLEQDHRKTLDYVTRLEQENQQLRDELRAVRESQSSVIAPAEEQIIAQLEDAIAHLANQVELLTLEKQSRGVKPALGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFH6</accession>
    <name>A0A8K1FFH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_010728</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1106"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1137"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1175"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1214"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1243"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1342"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="48"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="764"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1368" mass="152803" checksum="8A56F373B825FBB2" modified="2022-08-03" version="1">MDGSKPLQPTIEYTSGKALMQHGSEALHKFYSTHMETALGKAMHQMEVRFHNVSISAEVAMAEKSKTNELPTLANELKKGLLGCAAKSNFATKHILKNVSGVFKPGTMTLVLGQPGSGKSSLMKILCGRFPDSKHITKEGEITYNGASTAEMKKRMPQFVSYVTQRDHHFATLTVKETLEFAHECCGGVQFSDRLEAILNKGSPEENKAALEASRAMLEHYPDIVIQQLGLDNCQNTVVGDAMIRGVSGGERKRVTTGEMQFGTSLVTFMDEISTGLDSAATYDIIKTQRSVAKNLRKTVVIALLQPSPEVYALFDDVIILNDGEVMYHGPVTKAVDYFRDLGFVCPPRRDVADYLLDLGTHMQHRYEVARADGSKHPRKPSEFASIFRKSIIYDEMMAYINGPHDPALLQDKDEMFNLVPEFHQSFWPSTKTLINRAFKKMSRNTAYFGGRVVILLIIGLLNASVFWQVNSSNPQVVLGVIFGSVLFFGLSQSAQIPVFISDREIFYRQRAANFYRSSSYVLANMIAQIPVSIVEAVVYGAIVYWMCGFVATATGFIIFLLLLFLTSFAFSSLFFLMSAASPDLHVAEPISMVSILFFVLFGGFVMSKDQIPDYFIWIFWLNPISWGVRGLAINQYRNDEFDVCEYKGIKYCEQYGMKMGEYSLGLFAIDSGKEWLWYGVIYLLAAAFICMSLATYVLEHKRYEGHHNTTLNDEKDERQFNKIPVSDSETEDNQYALVETPRRDIAVNITASPYERRITPVSLAFRDLWYAVPDPANPKEELNLLKGINGFAMPGKMTALMGSSGAGKTTLMDVIAGRKTGGKIKGQILLNGHQATDLAVRRATGYCEQMDIHSEASTIREALTFSAFLRQDSDVPDAVKYDSVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLIMDGVRKVADTGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGKDACELIQYFESVPGVDRIEDGYNPGTWMLEVIGAGVGNTANQGTDFVELFNNSEKSAMMEEKLAMAGVGIPVLGVDAIEFTSKRAASELTQAKFVIKRFMDLYWRTPSYNLTRFVIAILVALVFGLSFLSIDYNTYQGINAGEGMIFMTTLFIGMITYNSILPIASEERASFYRERASQTYNAFWYFVGGTIAEIPYVFGSTFFFVLIYFFMVGFTGAARFFLYWVVLSLHVLTQAYIGQWLAYAFPTVEVATIVGVLIVSLCLQFMGFNPPSSAIPNGWQWFYQIDPPRFSFTSLSAIVFADCSSSENTTELACKKMEYLPPTVPSGLNVKEYVEQVFKAKYDDIGINIVYMVVIIVFFRILAAFALRFINHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG08</accession>
    <name>A0A8K1FG08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG08"/>
    <dbReference type="OrthoDB" id="123721at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439:SF440">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="435" mass="48964" checksum="0622150F6AB3972D" modified="2022-08-03" version="1">MGSIRIFLSVCCAAGYILEQLDVDTAFLNADLKEDVYIEPPEGLKVDGDCVLKLNKALYGLKQAGNAWFKTIHGALIDLGFKPCGSDTCIYVGRAGGDTTYICLYVDDMVVGGRTQTRVDEVKKLIAARFRIKELGPVKHLLGMEIVYDRVKRYLSINQAQYVKTLVERFNQQSCRDVTNPCEQSLKLSKADGPRDDQQKAEMSKRPYRSLIGCLQYVAQCTRPDIAFAVTHLSRFMENPGPRHWTAAIRVLRYLKSTRDYGISYGGDHEENTPVVFCDADWGTSVDDRRSVSGLVIMMNGGPIVFKAKYQSTVALSSSEAEYLALSLCGQEVMWVRTMLHDLGINIKKPIQVWEDNQGAIALAHNAGYHARTKHIDIRHHYVRDLVADSVIKLSYVETQRQLADILTKSLGTKRFEFLRELMRVKPTEIPPSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGC2</accession>
    <name>A0A8K1FGC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGC2"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="94"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="32900" checksum="05C2CF39588CB0DF" modified="2022-08-03" version="1">MSPALSPRQMTPEPSTKTPLKTDKAIRNPSKWRTMRKILIALGVIAVLAVGVVLALHFSKTKEFDELIAWIQTHQLIGSVVYVATFTLFIILCFPSTAFELLAGYIFGFWLGFILASVGKLLGSVLSFVIGRYLCRKRVKEYMERGHPVFKAFQSLLRKRQVLVVFLTRIAFFPIAMKNYGLSVLDVRFMVYFMAALITGIPFSIIWVYSGHAAQHLTTLLSDSKANHQTEVILLVVGAGSALLLLFFVGYYTRKHILAMAEEETAVEEQAATQENESAAMMEEDAAARVLREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGG0</accession>
    <name>A0A8K1FGG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGG0"/>
    <dbReference type="OrthoDB" id="119286at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="30258" checksum="267D92A632787B94" modified="2022-08-03" version="1">MRRRHRRQWMVMMEVVEVSLQAITLRNLLLRGHQLPLIFVYVVLIVLNCATTFYFVSIDWTRDFSDEMTVGAILDMCFAVFFFPATQLAYAIKTFRGDFEMLRIRQHIIELVRKKSRKIAEIPDTKSISPKKSVVRMPSTVSKAIHTQVSGIPSIVGILFLFTGIVLSVLAAKAVNTSTMLCGSYASSCPVYPYHSFMEDSKAACPCLAFISQSINPIDKERVGPPPEIMTNLSIHAEAGTLRTIQIINRDLNPSLPPAVQNCVHLQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHE7</accession>
    <name>A0A8K1FHE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHE7"/>
    <dbReference type="OrthoDB" id="10039782at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="20449" checksum="A592199C4C367CC6" modified="2022-08-03" version="1">MWRILTIERSMKRRQAETTDGHRVWVGRVPSHLCVDKSEAESYFGEHGEILHVETQHQLIDMSADGFIFLTYATKEAAMAAVDAVESGRRAGDHEMQAALALSRGPVVATVDRDVADLLLGRRQASQANRFSQHSMMDDTEADEEELMLQSLSQRSFTSSKKHKKHKKRKMKMELSFSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI89</accession>
    <name>A0A8K1FI89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000584</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI89"/>
    <dbReference type="OrthoDB" id="10265275at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="29741" checksum="8055D5762571A077" modified="2022-08-03" version="1">MVFDDAGASSLEQFTLLAKNARGRACVALIQQALSNKKLFVFRELLDMPNVQALKGTEHDSYFQLLEIFCFGKYRDYLAEKDVLPALNPAHIQKLRKLTTLSLAQKSKIVPYETLMKELDVTTIRELEDILIDTIYSGLVQGKLDQKSKSLIVKYAVGRDTQNADVDLMIEKLTNWQIEATTICERINSILSHADKLAESEKSREENIRAKNVRTAAERAPGSREGNYRGGNDDYLSDFMQGPRRTPSAKRMPGAPGMNRKGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIB0</accession>
    <name>A0A8K1FIB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIB0"/>
    <dbReference type="OrthoDB" id="9909311at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF57">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="68"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="29177" checksum="2B244BF0A71BA89D" modified="2022-08-03" version="1">MGPRGAGRRLNDQERMEILDILSKEAKVKNVDLAKRYGVSEGAIRKLKQIKDTIRERYQMGNEQNRDKRKRGGFVRNAKFEQELYEWILHIRETASYHLIPLTQTAVRQQAMILAKKYDSMANFKASPGWFARFCSRHRLDPPVHPPLTAEDGSAISPVLGLAATAAVGDSVPGGPLASAYQVDTSFTAHLTAPVKTTGLENGESMPDQTHLAAAVADASGLSGIASDLTHVTGDVKVERPKESKGEHAVPKPSPVPTEEEIFSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIV2</accession>
    <name>A0A8K1FIV2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIV2"/>
    <dbReference type="OrthoDB" id="96297at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="386" mass="42923" checksum="19862D30E432D903" modified="2022-08-03" version="1">MTYAEYIDEVFAYCAAKDDMADHGYTVNTFMWNKIMDPEKTCIPEAISYYFRKEWNIMGKCGDLLLDFNGYIGKFDDSFLAANGVLSASTKKTLWISKLSCPLLITDCSKADISGSKSEIQALWEPIELGQVLRLVIRHCPELEIPASIDQFKGLKSLKVYNSTVVRWDDTTTTIKSATHPLLHSLQFVRTNFSGSVLPPSLWSAEFPRGVTVIEFCITNLAELPALVASRWPQKLRLTWEASSSSNLFPLLLEMNPTQLSLARNDLVSIPADLLEVSTLVALSVAHTPIAALPFNVSLSSTLEQLSIVGSTVSEMPSWFYDDLLARPRRWMSENLALFAGGSLYCQAIATRTITNGDRIVCASTRDEVSYPLDQEDAQSAFKAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJX4</accession>
    <name>A0A8K1FJX4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJX4"/>
    <dbReference type="OrthoDB" id="96297at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="32508" checksum="7058E53234138050" modified="2022-08-03" version="1">MLWDPIDISQVHRLVFRHCSALDMPASLHLFSSLKSLKVFNSTISKWEALTSALTAASHPLLRSLQFVPTNFSAMELPTGLWPLDFPRQVTVIELCWTNVKALPPSVSARWPRQLRLAWEGCDLANVPAVLLEMEPTELSLARNPLTSVPASIFTLPALESLSLASTPLTSLPGNLTLSSAFQQLSIVESKMSDMRSWFDEDLLMRPQRSLLSENLALFAGQSPYCKEIARRDIKNGERIVCASTRDDISYPLGQEDAQSALTNANNWLLIVDLSKLASFIDSQEDISRNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK62</accession>
    <name>A0A8K1FK62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK62"/>
    <dbReference type="OrthoDB" id="105025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48616" checksum="CD43AAE6C0DAF9CD" modified="2022-08-03" version="1">MRSPVPESALPSITLSPEEERQYEAEVEAVIAETLRVQRRFAADGSTLEKKHWKTVRSKEDFHVYKSTKSSRRTTTAVNLNATLGPTVGSIRNVNLSSNSSSSSDDDDGIVASIKDPNVPLLIASGRLEGHLDDAMFACFAGDDLSWRQRSTYLKDRFAEARILATIQAPTPENPFNFLGIKWFMKEQPPLVGSFVQPRDFLILEASGTSVDEMGERYGYYLVHSIAHPKVPAFNELNIIRSVVSLCLVSRQVTPETVHTFARGFSDPRGDLIESIAVSHTADTLSAFMNAMEGSYVKKLTWMIQEAERRRELERQYFISPPGMEECDLCQKPGGKNLTTCRVCAQTICVRCTVTRKILVTDTETDSLNDCTAPFCFACVLAAKTRPAREVAIATSVLEAVRRQPEKAKATPDRPGSMLYTSETRPQLSKSTTGVVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKA4</accession>
    <name>A0A8K1FKA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKA4"/>
    <dbReference type="OrthoDB" id="71118at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="904"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="977"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1010"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="345"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="930"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="988"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1022"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1063" mass="117426" checksum="B0A3BCE0361C9154" modified="2022-08-03" version="1">MSKGRSAKRPSKEKEALLDDGALWASIQLASASPKDRSPRVTTSVRPVPLPSFEAVSSIRLYEDDVALCSRASPVATKQETKKPLRNAVSMSSTTLASAMKTESSGKAVPRARSLQEIRTEKPTVMNSGDEAMDHRLFVPRDQWIQHNHRKACVVCDRDFNVLRKKHSCRMCGDVVCSRCSVFKSVKLPIGLSKARVCSRCFLAYRNGAVQVKCDDESDDKSKTTPVEELETKAINISPRPTPSPLSDRPAQPVSLLTPDDLAAVSRTREAAAPVHTAPSIMLLSPTKSAELIFEMRLEELKKSYTSTMSTDLLSSPSISSWSSASSVVSSASLNEEELAAAMKARELEKEVESSRQRIGELELRMQEQENQKAELSQEQQNQLTEAREMIAMLQAQLRQQEQSARDAAAVRDSMYMSHMRPPLAPTAPTGADRSSARSRRSGSVEEESATLKQKLRMLERQLQQAGINVAEVIPYAVATKRIAEIARRMAEITDAETTQHLDGAALVALRREYYVLEQDMERFHTALLMSDEYQEQQKQQEQEWEDQHQEANTEALRTVRTAMPVNIAQLSEQALRTLETPSGQRGIPSELARRFKRTNVLQLLRVAPEAIVRMHPSVIENYRTTGLSLLERRALHCALRQAAVEWKKQEREEQSQKKALWFKKLKDGLTQAIRTYEQHYEQAHATGATCKLLGKACPVRQEAAIAALYATELGFPSDAVYLTQDIVKSDPEGAGEKALQEAQAHARAALANQRHMMLKAHYGMNVREVAVAMGALEDMESLLERIRALDHHAFEAFSPLDENSEGIAERAEKERVWERLLMEVRELTQLMARRSGICLTGKRDPTKDAVDSRSPLEICVANGVALYMLSMFEDLEGVVGQQSKSNGSLGRLREMLGEIQSKNKAIESSSTIEGDAGSKPSQDGGVATDRVRWTDRVRTKPSENETTTASATTIEAVAVAPLPRGAMLLDAIRAKRKEKDVEQSPASTVKSTSSSKSTDLLAAIRAKRLATSTSQNEAEQKPLPAKKPSASSSPGDLLAAIRARKKRAASDASVQSETAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLT2</accession>
    <name>A0A8K1FLT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_011106</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLT2"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000027">
        <property type="entry name" value="Poly(A) polymerase PAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="16">
        <location>
            <begin position="57"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="15">
        <location>
            <begin position="247"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="14">
        <location>
            <begin position="400"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW67486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="567" mass="62960" checksum="201D3BE62FE48BEC" modified="2022-08-03" version="1">MTSPTPSSQRVDLRRSPNKDGIVGSPLQLAPVHLAALSGVKGPSSSGGYAPRLRQVVQPMHIGPPTEYDFRNTNGLMKCLNALAPLPAPEDLSAKHLVISELQRVADQWMRETFPDKPEATATLLLGGSWHLKVGQADSDLDIVALLPNFVTSEVFFDSLHKYLQSMPSVSKLVAMTKATAPILAFQLNGVRIDLLFARYTQDIVPKNLPIHSDRILAGMDATSIRSISIPRVASLILELVPNGSAFRSCLRIIRLWAKRRGLYSNKAGFLGGISWTILVAFICQMFPKATISSVVHRFFSVLSTWNWPTPILLSKPYDCSAVDNCIQWSPQNNHHDRGHLMPIITPGFPAVNSSVNVNVSTLRILQEELERGKYIMDDMLAKGLSSPAVWQKLFAPSEFLVRYDHYLVIELRANSDDEMSEWSNYVSSRTRKLVETLEHTSPIQSVHPYPDLIKRQTDSGDCTSGHYFIGYTVDPLATRSTPATGVQGDRDIAATCVTSAARYFSATELETFEERKEGMTATITYARWQDLPEEVFPSGRTVAAGERARYILQRAHTSNITLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLY7</accession>
    <name>A0A8K1FLY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLY7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18748" checksum="5A96EDCBE09EB957" modified="2022-08-03" version="1">MMWEGIADRYRITGMVSDGTYTTVFKAETCRSNDDCNGDDDEEPLAVAIKLIQPHGFDVLSVTIERDITILEALRHDNIRGGTLRPDLSIAGIMTQRSDLQQRRRWSTSTSSRLNQSLVTGHSMNVGRNRYRSVFRDASGGRSAPVGGSGNWATTVELASGREQAEREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMM1</accession>
    <name>A0A8K1FMM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMM1"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="583" mass="65578" checksum="94F6BB57FA657FDF" modified="2022-08-03" version="1">MSRRDVLEAGVDGVFDLDAMSERVMEIDVQASETLREKGNVAFQNKSYEMARSYYTQAIAKNPQNHLLYGNRSASSCHLKDYDRALEDAEEAITLAPKWVKGYLRKATACEGLKRWNDAMEAYKQIIVLSASDSAAETKKANTRIAQIETLVSKGAVQKGFFETSSAKAKSSIYAEKEDIVMPVVDTATGQTRLEDGDERRWRYMLKRLKDGCNKHGVNGKGERVVLDDGVFAKLRNEHDFQALIFPGIPKEQLVHAPKNILELLEDPWYEQELLSLMPKVQQKADSVLTNVKKRGAAQGDIMDAATEQMLRPQVLQEAFAREVLSMVHRINYKKHMLLATDERMMADPNAEEATWDQLSEPFLDDLLSKTPPDGSAVAGAAVLDEFMGQEWTDLLRNDVQRMHKNGLLMPTTNIHAGASTLSTETTSTSTSKIGQMRFVEKTDCEKEYPALAELLEKLHALPFEINKKRSERAQLCAQFAHCSAVHHLQAGEAQPLRLDCGVGEKDNGFKLTCVYFFSPLDKDTSLCLRTNLDVDGPVQRVQPQADRLVIFQSQRVLNEIQALADGQELFYLTFWIHGRELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMS7</accession>
    <name>A0A8K1FMS7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMS7"/>
    <dbReference type="OrthoDB" id="58453at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="28368" checksum="1D554745DCEB09D7" modified="2022-08-03" version="1">MGLPSVPSVKTPRKWIAGRMSNRFRRGNNGETEPVMESLPEDGPQEPESEHPPTENQGDAEAVNSNRATRMSRVSSLFTRPTYKRSSTTRESRAQSNMETASTPRRRMNPKQWIMSKMPFRRAKSESSARSTVSRASTTTSTEPDEQPTPGNARRSRVYSVFNRPTLKKPKIRGKRAQSNFEMSDSQYTDDSSVGLDDSSVGRKGWKPCAFCSRSFQFKTSKYRDYCSVDCKTASLLSKGAENPKGRACEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMX3</accession>
    <name>A0A8K1FMX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_006214</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMX3"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="15">
        <location>
            <begin position="46"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Cysteinyl-tRNA synthetase class Ia DALR" evidence="16">
        <location>
            <begin position="441"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="601"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="601"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF09190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW68746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="686" mass="78220" checksum="56E186CFE4091A32" modified="2022-08-03" version="1">MATTNASSVKQPTWYPPRPVDTMLEYWEKHYPLRLYNSLTRTKTAFVPMKGKRVLWYMCGPTVYDQTHLGHGRTYTCFDYVRRILEDYFGYEVELVMNITDIDDKIIIRAAENGWVDAHPGQELPANKEERTQVVMQWASEQPAEENMRRTKELAKFWEKSFLDDMQLLNIKTPAVLTRVSEYVDEIVEFVEGIIRNGYAYESNGSVYFDVNAFSQTRGMAYGKLVPENVGQSGSELLAEGEGSLSSLGKSDKRNPSDFALWKKSKKGEPYWQSPWGEGRPGWHIECSAMASDAIKHLAEGKIDIHSGGIDLRFPHHDNEIAQSEAYFNFSQWVNYFVHTGHLNIEGLKMSKSLKNFVKIQEALMDNTSRQLRFLFLLHKYNVPMDYNDNSMDEAVGVDRFFSNFFQNVKAKLRELGVEKPQKWTDVEKKLNGAVLECKEKVHQALADDLNTPFAILHLQQLAKEVNRYLATDLEHVSMIIRSAAEYITRILGVFGLTTNGSDIGFPLSTSGDGAASQETVLAPVLDIFSKFRDEIREAARAGVTSGNVKDLANAILKLCDDVRDEKLPLAGVRLEDGSGSSTWKLADKDELLREMEKKAEEKRRKEEQKRLRQEEEARKKAEQEAKAKIKPEEMFLGEKDKYSKFDDSGIPTHDAAGEPLSKGQIKKLSKEHAKQKALYEKFNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN03</accession>
    <name>A0A8K1FN03_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN03"/>
    <dbReference type="OrthoDB" id="161806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="349" mass="38899" checksum="71C4CF704DD8D1F5" modified="2022-08-03" version="1">MGTAGKHGTEVNMHDGKCGKRKHGAEVEEETGPTISRFASPNYFQVFQDSDIDLEFVDLDEESNYFYQAQPTKVIPARHGKEHVILLRRDGAGVGKKKKPDSIKAAFKSMKADCDNVPISGSRSAADLFSAGTPQVLTHGSNGDNILKHIRADPATACGQLSLLMQEQADAVDDLAELHLITRILGATYQTYLPFQSKLKNIILAPIASKQQLFELFKALRPQDELTEQGWEQHKALALLELVFMAAAPRLFQSEFWLHYLAKTAPGWIPTFEQRLLDNTVLLQVLRSPIGAFFLERWETLKWKSELPAVLAELRDGKTTLSPDRSTLFVVQEPAGTVVLREGPFPTQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNI3</accession>
    <name>A0A8K1FNI3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNI3"/>
    <dbReference type="OrthoDB" id="125728at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18459" checksum="03603A68EB574015" modified="2022-08-03" version="1">MIESAMSIALEDILGDTAALDESIEVAELSPLPPPPPPPVQHPDRTSALLQHLSISESQTDALRMRYQERQRRREQEQVEEASKSKQSAEFYRRITTARLEFEQRKLAIQSLRARIDREMQFLLATAQELEAREELIEDAFRGYEQLLRAEYGLEPDAHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP48</accession>
    <name>A0A8K1FP48_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004307</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP48"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="108"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="202"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32464" checksum="5DCAB47D3C66F8C8" modified="2022-08-03" version="1">MAAAALDATKHEVATHRAVKSKKLAAGALSGMVSALAFQPLDVLRTHQQGAFGAQLASTALKTQVTTQSLSERVRYMWRGTSSTLIRVSGGAGLYFMTLDHCLGIAPNTALNTFLSGAFARTFAGCVMSPFTIVKARMEWQAPGTYKSNLDVLRHVLRDEGVRGLYRGIVPTMIRDVPFSGLYVLIYKRTKSALEQRSTTLPPYALNFASGVFAGVVATTVVHPADVVKTRMQLTIVGTSDQGEVKNIRNSLTLRDTVRKIWIEEGSAGFAKGVAPRVLKRTLSTAVTWTIYEQLSVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPQ0</accession>
    <name>A0A8K1FPQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CBS domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPQ0"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="86"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="255"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="321"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="5">
        <location>
            <begin position="467"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="62951" checksum="E2D01AC863C8B815" modified="2022-08-03" version="1">MKKTHLVYSTRKVKAKEKAATVAPPVVNDVEQTLEVGTTMLSATTVTRQNSANSRDGGNSRRRSQTQPKSKQRASMRLGDRHVMKLRPSTPLLQSEHVTVAQCVKSMVENKTEATLLVDRNGQLTGILTDRDIAVKVVALGRNPKVTRVSDVMTPNPHCVTSDASAIDALEKMVAGHFRHLPVADNDKVVGIIDIAKCLYEAIVEMEKDYNESSKNLAEAIKKLEKQMGGSARENLFEKLREKLFLPTLSAILEDHSPVPVLGPSATALDAALLMLAKRTSAVVVCNEGEDMVGIFTSKDLMRRVVALDIDPDQCMLSKVMTANPISARLNTTILETLHSMHNGQFLHVPVFGEDAKLVGLVNVLQATCAIVQQLGMFRMSKSDTETIQPLWNQLRRSFVRDEDSHGGEDAEEDTVLSLNESGEVPQLDQSELSASDRQRSWSSVKDEGPEANDPALSESPEVETPPPDVFVFKLADWNGANHRFTSSAESLKELIKDVQTRLGDHTIRKLHYVDEDGDHVLLFTDDDLKDAVRRARMWGNKYMRLLVVHRIPPAAAIAGASFFLSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ09</accession>
    <name>A0A8K1FQ09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ09"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48455" checksum="9120A562745CEFFF" modified="2022-08-03" version="1">MSGSLTGVSTTFTAEELLSALDGYDDLTLDLLLDTSADAEYAPADNVSDSAAPFHSIMSGDSVGSTSPPSSELSESPSRSTKALTQIPRSQRLKAEREFLREQVVTLERELAKAKANRLNNISDVWRDVAKRQRTRRTSAEKENERLRARLMRQMQVAKSLEVVLRYRDEHHLPFVDVSSKTEASEWKRDLGQVFKRFVVEIQRAYQSLDSVLPEIYAPPQEEALINRSVVKSHAVDGVEQLYVETRQTYVLPFTYNQVAKVAWKAYTTQFERQGRQLELYLRTDDLFACKFGYQDGGDDASDRKIAVATTIARNFIEEDRYAVVWRCFVAEQNATFDEAVAVCTGWIAIRPYASILDHTVLHVCIRTSPENHVDLFALQAQNLIRLPTKAPELGAFLSQKLCTLAEDIIMVTDTIQDLILDEALSNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQM6</accession>
    <name>A0A8K1FQM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase/HSP90-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQM6"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54025" checksum="96987008F769B084" modified="2022-08-03" version="1">MRGHGDRRSKFLRNNLEIMGFGNARDALIQTTKELFENALDAVISSHTSWKDTSLEMLRVSVALNQKTGCVDVVCADTGSGIRTHQIKQLCAVAFETTKDGGGSERGSNACGKYGIGLKAATLYAQQQTPTACLKITTTPSSTEILHVQLRIDPESEQPAVVENLTQFVVGDDHQFFSGTEMRLAIPCPEDDDEVEYAADVLAMYFQSLRYTVPPFVGVQFTLDIGDTSIEVECSHGENPVDRFTRDLDVASDQIAYFQREKDGYSVNSMGVMKSPPSEVDLIEISVLRYANHVPVLNADDIQTCAIIKGVQKCRTWKKLGYRCRVNESHLICQLAASPALIESSSTDDRPHHHLVVAVDVSSSASTSDSIKYGGLRKTTLDKCYTSAIQHCCSQILEQLQSRGVLRSPRQCRDDELVDTFVPLIANAATSILNKCPRILQPHHVNQTQDEEENSEDVPMDGVYMQFDPELVTKRLQHVVQDALGVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQQ4</accession>
    <name>A0A8K1FQQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQQ4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="397" mass="44233" checksum="C9B2E8035C2ECABC" modified="2022-08-03" version="1">MSVIETEFSATYFAILHRHCHADLLSRHRFLALDTYIASTAYWRKVLVVLVAPLPGLAAAIVPTFFPLQHPRLGPNLGYYAHAFWLMFATSFGTLIHLAEATSIPRDVMSMAEIVVVSALSGVFQCIDFYVVVRFIVYPIPFQLALVATPWIISLGLALVLVLSRKFTHNTIFREALNTYRVCLPIQSIQLIVYPSLSVFYDHVNDTGKVIVILSFPVVKYFMKQLLHRNSKHLGDFHAEVSVSGIEICASLSATSTVMVMGLDVNMGLFSIRVFLDHHGRCLDVPRDEIVATAIRRLHEPRPSPIVPAAASVNSSSRRVSTGGKRKIENEPVVVAARGIADSVERILLVEYFEVIIPVINSGFFLVASLLPSAHYNPRIAPFYQDPHRLRSALQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS40</accession>
    <name>A0A8K1FS40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS40"/>
    <dbReference type="OrthoDB" id="2021159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF5">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="1">
        <location>
            <begin position="39"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="30065" checksum="53E6C76638D4E025" modified="2022-08-03" version="1">MTHGAPAAADVRVTHASTTHSPSLYVNEELQRRVNERVTVAVVGAGFLGRCIALDLSMLGVNVLLYDKNPQVASALSAFAYEQLNPMLHLGYVTKSMLTRACHHVRVVSDLHECANASLIIEAIPDDLGAKIELFRALERVCSSSTPLATSTITFSVESIQQQLSHQERFLGVRFFHPCVLVSPVEVSVGPATAQCAVTSVVQLLRSIQKIPHRGPTKRVLSNREVSAFQFNTAVRGHFYHGLLEPKAHSLSDIITPADGPPLVDESEELRGSTTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1W9</accession>
    <name>A0A8K1C1W9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000169">
        <property type="protein sequence ID" value="TMW54921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1W9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="279" mass="30445" checksum="93D1118B7B9F1B70" modified="2022-08-03" version="1">MESPNIKGDYDYAELEIEKVPAPAPSAPPAPDSEAFNNMFSTESERSSHDQTRNRPPHQPTRAPSSNSKNLLFALKVVGYQLANAVLAFAAVVIVATMLFLSIALLPVFGLGFFVYRGALPLVREVAMLDSKLANLITPDGDRVCFTSARPGAESILCVAPDLHLVSLQSTLVVAYYLTLKPLIAGASIALFALVILPFLPIMRDANGYYYDNNANRWVAGIEVGSFLFYADPVWYALGCRDLDLDQIARLPIKRHYASRLLSACSSNGCTSCVVVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Z1</accession>
    <name>A0A8K1C1Z1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000158">
        <property type="protein sequence ID" value="TMW54933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Z1"/>
    <dbReference type="OrthoDB" id="100116at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="1">
        <location>
            <begin position="10"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="24144" checksum="7D2255ED231DB080" modified="2022-08-03" version="1">MSFPGHIYGKYKHATQFFLDWMLRAGASTGASPAPRNASIRVLQTAVDELVGKRKSLGSDELRELPLALTAFQIAITLREHVASFFDAEEANTSGSEDTHAHFLNSKKTLVEATAVAKVAIQCATSAIARFQLKYPSVRDADDVFTLLEKHLSSSPFDLLSTLVIKEWYKGHRAKVKVDAVPGGIIVDFSWVGSALLSFRNDIPIDHRVRLSGEGFGKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Z3</accession>
    <name>A0A8K1C1Z3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Z3"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419025" description="Peptidase A1 domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="74"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="442"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="314"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW54967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="56122" checksum="7EC82EF1D3A12298" modified="2022-08-03" version="1">MRWRLALAALALCVAPSDAATPIRIALSRHAPRPTATEAHAFRQLHASVDAPSPATTFPPGKAVPLKNYGNVQYIGKVAFGNPPQHFTMVFDTGSSDTWVPSADCNECGPHNLFEHTASTTFLDSQEKFIDAYGSGSVTGTVAVDTIRLGEYKVDSVKFGVVREETEKLQAFIADGIFGMAFEGLAQISRPTVFTALAAENPEIDNMFAFYLTPEAYRAGSELHIGGFDLSVVGPNASFHYTPVVKLPEFDTYMYWTIQLNHFSTDKQSTDNICDPFCYAIVDTGTSLISVPDGQYAQVIQTITAGLNCQDVNCDGVSVSDFPVLRFGMVPDNVFQLQPRDYVQCFGWGQCRVQLQSTGDEWWILGDVFIKTYYTLFDADNMRVGFACESDTCTGGRGDIYGGDDGSDATLQALKNAFLIGSCFAAACMFLFVFYMNQQDEGDDERGANDPKTPLLHADAEELKRSSRRRPQETTASSYEEARRNFSALPSPQTYTQQQHEQHEQDATSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2I0</accession>
    <name>A0A8K1C2I0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2I0"/>
    <dbReference type="OrthoDB" id="127762at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30323" checksum="FFDB2BAB993C5740" modified="2022-08-03" version="1">MMEPQASECDGALSPTRALPADATSTTATEQRDMFFFRRPDLSGRHLFFQGNGRSPRAETQAEPQIAPVQLVTMDGQSHLGVPLVHPSGLRSRHSETVHSNTRRDGARPQSERLSRLLVTSEPVSDLDGKLRLRRNTIAFTAAICIKIIFTILMLFPDSRDAWFHTDVAGSVLGRESMNRVSFVRTPLLVLGGVESLLGIVSVVFQRENLIAVYVLGLIASDMYTVVLLLPHVFFLLRILFDGVLLLLAWDTRSHLTQQWFVTNFHRLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2L2</accession>
    <name>A0A8K1C2L2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2L2"/>
    <dbReference type="OrthoDB" id="165696at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="66093" checksum="83F771A57CFDD6B1" modified="2022-08-03" version="1">MATAMDSVELRVRALRGFPAHDADAFDAADASYAVVEVSFACTPQDDAAMDASQAESPRFYHVERSLADFMHLEKRVFGSEAGGKIQNAMEKLLVSGSSALLSMKQRTERLMWHLEAFLIDVSTALDGATAFQAFVHPHASLLHQDGAQERYHALIEQVLSSESTEKQEESLAGGCSMTHVESITSVSSLVVWKFGFQGTAIDFSARLQGEDPHNEKQDVDPYSATAFAAAYAFPEAEQDGDIVQYTTRYTLGTSQTVYGAFVAREKGALTFEWTNPDVDSIFSKALWYQVEVILLPSELEAAQELEKLYEADDSDITWLEQVIYKHGSSKLVQEREENGMSASGDVSDDDVTVWKYVSKPTSVEEVPPQPEQSQRLQNQVVKLEEELQNVRLELKAARSELDISAEVYKASLETIAHLEAPVRTTPPSQLPADDVISYHSSEEDDEDEDDDDDDDEVNDEMKRLRDLCATFQEQCLWRSIETSESEKRNLILEGDLSRAEEKVEVLRSKLATRDAELEEMRAENQKLKAQKSLLVKEVKRLQPFSQVNLTALVQDAEEARMMQRSLQAQLSALRQEQQAEVPAPECDPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2V1</accession>
    <name>A0A8K1C2V1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2V1"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="405" mass="46214" checksum="D983867FEEEC2658" modified="2022-08-03" version="1">MRHLHRLVKNPSARAWLVGAVPAALGAAALVNHQNESQCKASRIPAEAFMYSKFSPDRAPKDSIEFDTTAPMNKRMEAMILRVQDEICDGIEAVDGKKFTTSQWEREGHGGGGRSRVMQDGNVFEKAGVGVSIVHGKLPPAAQKQMRARGKPLEEGKDLPFYACGISLVMHPKNPMAPTIHLNYRYFEMETGRLNDKGKPETIAWFGGGADLTPSYLFEDDARHFHSVYKQLLDKRDPTWYNKMKKACDEYFYIPHRQEGRGVGGFFFDDLEDTSEETFQTIRSCANAMLDSYVPILKRRKDLPYTQKQKEWQQIRRGRYVEFNVMYDRGTKFGLATPGSRVESILMSLPLTARWEYMHTPEKGSWEDRTLQVLKNPVDWLDVPEVNLETLSTAELLQEIARRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E6</accession>
    <name>A0A8K1C3E6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010581</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3E6"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF212">
        <property type="entry name" value="ZINC_IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="45032" checksum="9AB68D389507285D" modified="2022-08-03" version="1">MTTTASAVLTPPPTTELDSAEGIETFKYIVTGVVLIITVVSSLVPLWISRNGTSHSRQLLTKKLPFVTAGVFIGSGLLHLLPDAVKMYNKVIVASPEWFTEKWMRDFPTMYLLSTIGCMLVWAVDLINLGDSGKMMAVASAARPNYETSMYRVQIPPVTSLGVRYRSYSVDDSKNNSKRVESCVCDGPPTLTQKASFHKGAKTEETTLVFMQHGIAVVGDSKSAPRSYTLDHGRVASEEDGLLSTQRQDSTSYPETSVSEHVVFSGASPVLPYLLALLFSLHSLIAGFALGVNRTSNKTAIATTVAILSHKVIEAMSVGANFARAKGDIGEQRAIAVLLLYSLMTPFGILFGMLLADALQGTAVLVTESMALSVASGSFVYLAFHEMSEEHGSQDTPSVQKIVLFGAGLFSMAALATWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C446</accession>
    <name>A0A8K1C446_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sulfite oxidase</fullName>
            <ecNumber evidence="6">1.8.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010664</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Energy metabolism; sulfur metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.1" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C446"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02111">
        <property type="entry name" value="eukary_SO_Moco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.650:FF:000002">
        <property type="entry name" value="sulfite oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="14">
        <location>
            <begin position="103"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00070338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW55782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="622" mass="68320" checksum="3530746794FB4E68" modified="2022-08-03" version="1">MWRALAPRLQRARGAVSFADGRSIRTVTRGATVAASEASWKSGAPSNGRGAVVNQYAQSRRTAGWKCARVAAIAAGLAVAGSTAVAQAEEAGAPTPGERIESLPTFSLQEVQEHTGAKKNGTWVVYRHGVYDITKFIASHPGGTKILLAAGKSIEPFWQLYAAHNHGDVHKILESLRIGNLREEDVVMLEKLRKERYGDGPYSGDPTRHPALKINSSMPFNAEPPPELLMESFITPNELFFVRNHLPVPDVDVENYRLKISGLGIMKGKEISFTMDELKSKFKHHTVATTIQCAGNRRAEMSGVKQVNGLSWDTTALSTANWTGVRLSDVLASVGVEEEDCREGHDCAIAENIDTCDDCNCVIQHVQFEGLDVDTEGNCYGASIPIGTALDPRKDVLLAFEMNGEPIPRDHGYPLRVIVPGTVGARNVKFVHRIVLAADESPSFWQQRDYKGFPPNVDYTRDDYWKFAGDSIQELPVQSAITEPKNGSLHAVEAATDSSIITVKGYAWSGGGRNIIRVDVSIDGGKTWTPAELHESGRRQKYNRAWAWTPWELDVEVPPGTKNLDVMCKAVDSSYNVQPDTIAPIWNMRGVLNNAWHRVRVDVVEEVPTEDEEEAGDEATVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4H6</accession>
    <name>A0A8K1C4H6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4H6"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04818">
        <property type="entry name" value="PA_subtilisin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF6">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426992" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="11">
        <location>
            <begin position="61"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="569"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1147" mass="128806" checksum="C579B036603AD450" modified="2022-08-03" version="1">MHMCLLLLLAVCFVVVRPVSAEIETIVDADGHTAHFNGIRVLSGSSFRSFTNRFKRQLRGVECLTFHEAGNWWHYEWCVGRHVQQLHRFAADELSAAKTPANDWRIVLGRFARDTSKTLRILPLKNFSRLRNPEQQGYYAVQSYAQGEQCTASEDQSKSTTVLNRSVSIQYKCCIFRANETYIEAIDEPSTCQYVLSVCTPVACGFVQKDQYVLNAPAYVGEEERLGLVQTVKDMFYHAYHGYLKHAYPLDALLPISCRGETFELGKIQMLTLIDTLDTLAILEDAKEFQHAVHLVVSRSNFDLNTEVSVFETTIRVLGGLLSAHLFAIDEKLGLFPPGEYKNELLTLAVDLGDRLMPAFDTPTGIPYGTVNLRHGVPKGETTVASTAGAGSLSMEFTMLSALTGDAKYATASRKAVRALFERRSSVGLLGKHIDTKSGDWTETISGPGSNSDSFYEYLWKMYATFNDQESLDMFDSVYTAVLERNLHGDWFADVSMWSGCGHGGVVFENLVAFWPGMQASLGHLHPATRSMNSFYRVWREYGFVPEQFNVMQWKPVRDRGARYPLRPELIESTFYMHEATNDSSWLRAGAHFVHSLQKHTKTKCGYATVKDIETKELEDNMPSFFLSETCKYLYLLFNTTHFLRNGNYVFTTEAHPFPILPSKQVDPILLPTKTPTSTSVSRGRMCRKPAFWDALGYQVDYEGRVVDKTEACKRPVVKPAKIGKTEVIASADASFLSVDDWMPMIEKQLREQLDNLQVKNLKKLSMSEDDAEIAAADYEDAVHRDSPSEFLQGGPRVGVVRLDKMNGLQRFTRVDTGEWLETTGLQDPRYVVLSWFPERRGDPPFDVMPSPNETPTPEVISPISDEDLELASLLPFHRVYDFTHGRHEVALRRICELHVDVPTVTSSGSMRTGFTRSFKFSCASAGFGVHAHSSGSHNFKPAAMVLAEPLDACGTIANAYALEGKLAIVKRGTCFFESKVRHAARAGAIGVIVVNNEDEDRVMVMAGSDEFGDDMEDDDVHKRQRPGIKIPSIMVPRRVGEWLNRQMIGSEGEVRARIELMVRDRSADLLSLARYMELPDENRRVLDAPEVYPRIEGKPGNLRLLAPEWGVELLTVRRSSHGDVEDFAVSVISELQTFADSKLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4I3</accession>
    <name>A0A8K1C4I3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Myosin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006389</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65048at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF845">
        <property type="entry name" value="MYOSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="111"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="233"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="776"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1252"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1112"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1273"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1288" mass="146854" checksum="02D278CA4C88B2C8" modified="2022-08-03" version="1">MTVATSTRVGGLGRPPSPTLVQRNAPSKANENSSSTVMSTVQVRIGDLYWKQDGPCGWVLGQVLAHDTTNNSVRFCYVDESTGEMHSSDEYPPETLALDQSPLFPANPLFSTAADMTSLRHLHEAALAKNLQDRSSLQNQRPYTFMANVLIAVNPLRELQDPDKQLFVAQSLDRCPPHPYYIAENAYRQLCAVRAVMQNQSIIISGESGSGKTETSKIILDFLTTRAIRTSRSTSFASEDDMEPEVTPTVHPPPPSITSALSYPQSSRSDRRLTKLSPVALGERLMETIPILESFGNAKTHRNHNSSRFGKYMRLQFSNSTHELSGASIDTYLLEKSRLVSQPTGERNFHVFYELLHSKKVDYVKNELHLLPKQPEAYAYLNQSGCLKAELIDDGENFQNLCRALEFVGIQDEAQHEIFRVVAGLLHLGNVTISEEDTSEGKTACIAPDDEASKQALEHASALLGVAQHELSQCMLVKRIMTRGSRRNSVYYAKRDLRNAVYSRDTIAKTIYEHVFTWLMMQCAYALDYDSERSDVIPYIGVLDIFGFEDFEPKNRNSFEQLLINYANEALQSLFNACIFEAEQELYRSEHIYTPLNHSLTFPFGLPGVPMPVRKTSSSDTTLQLTGDESDSVVEYTDNRECLNLIASRHGGIFTTIDNVSRLPAPTDRKLNERLHTLFKRHTCFPTPHPKDARDMFIIKHYAGTVKYHINSFVDKNNNIVSDQFEELIKRSTSRILQEIIGRDTPSGQEKSSRGGGKRSSSVKGGSASSLFSTQMKGLTTELEGTACNFVRCIKPNTQMKPGIFDRPFVVEQLRCSGTVQACEVLRVGLPTRILYAEVVDVYKHLLPADMLQKFDFNEKLFTQSILWSYTFPTEAYRLGDTRLFFRTGKIDLLDKLLTPSSDSTAIDKLSADMLLYLRKKRWIGVATKMIACNIFKQIYYKCKYRRKAIIIQSMVRQHFARKRVRKLRVLHRISGVWNRISHRAQIMRAYQDRPEDKMVLLDKLLQRNYLPPDQRWLLKWLGPLQKVIYLQKLWKKVMAQYLAKRAFIWLLETVRQKRSALRMQAMARCMIARKLFKRLKTARLARERWRRGYLKVRVFCVFRRELHSIHVKRLENDNEMLVDAVREAEERVRAAVEEANRLRAKYQQMEAALNQKTAQVAEQTQRIDQLESELDDTQDELADLRHHAQNSMMERVIRFFTCSSATALPPVSPARSGRKKKPADVPTMAKIASVPSNASTVLLMVDGVPMRTSLDSDDEEDKEDQGNKESKGVQTTEVQWNDSRVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C519</accession>
    <name>A0A8K1C519_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006448</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C519"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000117">
        <property type="entry name" value="Probable papain cysteine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443088" description="Peptidase C1A papain C-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="5">
        <location>
            <begin position="57"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="45800" checksum="972E42E2B7D6D2E0" modified="2022-08-03" version="1">MKLAVHVAALMVLVSSVMADAGCKCHRTMKGREHMHPKVNPGLPALTLAEKKEMSSFPKHLDWCEEGFCVPSWNQHIPQYCGSCFAHGAMSSAQDRIKIMNQKKGFKGADVMLGRQSFLNCAPGHGLSDGCDGGEASDVYEFMMRYGLPDESCLPYNATDHTKFKATNGTCPPEGYCMNCMYTPQSPTKAVCFPVTKVVRYRAKRYGHLSGEHAMMKELLNGPITCGIACSNEFTYEYKAGIFEDTTGFMDIDHDVEIVGWGEEDGVKYWHVRNSWGTYWGMNGFFKIVRGKNNLGIEADCAFVEPDITDEELVWEEKPAYGGSIFGIVPFSDNAEQKHPIQDTNDITTRDKPTTGAIALAAGVDAALAVQRSTTQGVLASHALLFFMAGCACTAFIGFVALKARVRRYVYRPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5C5</accession>
    <name>A0A8K1C5C5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5C5"/>
    <dbReference type="OrthoDB" id="7250310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035468539" evidence="2">
        <location>
            <begin position="21"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="733"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="771" mass="83515" checksum="A0373A9EC59426EF" modified="2022-08-03" version="1">MRVPSALGLIAFVVLVGVKAQPSNSSGILYAPEPDEFGNPIIIYREPEASNTDSVMLAQDILMAATATGTCTWKANNVGFKCYWSKSATEQPSLKLKDDCAVTAPIPKDNYVGDKRTNKLGPDITIKTFKSGTSAALKTESTTWLDYATSPGTLENKITFSSFGTFDLKMIATDYRASGECTGCVAIIDTFRPKSQAGCSTTDTETSLDYSTTNLNTAIAKEDAFSAFYANVINNGDYDSTTGDNERDDLKTAKMTDFFDTEKDLSSIDSRCFESTFLKSLLDKRPIQLPSGPGAAQTELNGLVCKRCCTKHRELREYYYLYDCDMAKEKKKGCGDKCSYSQCLTVQPKDLILAKAEVSGAAQTLTTTVIAGLPTPPAADPKTIHQSITCKNFNEGCKYTPKLKDLFTHGAEWNNAAQVPSGYTVDNYVYWRYTVNTVNWKVWDDEDVLTFDKEDGRVSIEAWSSCGLVFQESFDIKLHPHTTHDACAGWKWTENTLSPRTVESYMCAYPKSDFALLTFSYDSDLSQSHQTSTVKGKYTDVKCYVKLAESGGIASVAKASFPLTVTPDAATSRIQLSKQLALELVHDPTTSKNTDVELTCDFTYSFFNSPDTVNEPCTSIFTITDCDVPEIETSGAEAVCRAGQCLDPASSGPYEACNGNVFTTVSSGSTLTTQAKSLSGQCCTDCAKTLTCKSLPESSATGGVQRCEPPPALVMAMAMEEASEMKSAQTSTAVAAGVSAMMALVALVVVKQRMAQAAKPAVDDAYVSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C619</accession>
    <name>A0A8K1C619_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="12">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_003025</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C619"/>
    <dbReference type="OrthoDB" id="1152826at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000266">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 9 12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="13">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="10">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW57100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="341" mass="36560" checksum="C4FA011A0AF27CE4" modified="2022-08-03" version="1">MPEQVKIGINGFGRIGRLVARAALANPKTDLVAINDPFMDLDYLVYLFKYDSTHGPYPGTIETKDGKLIVDGKIVHVYAEKNPADIPWGTAGATYVCESTGVFTSTDKALLHVQGGCKKVIISAPPKDSTPMYVMGVNHDKYDGSADVVSNASCTTNCLAPLAKVINDKFGIVEGLMTTVHATTATQLTVDGPSRGGKDWRAGRGAGQNIIPASTGAAKAVGKVLPELNGKLTGMAFRVPTPDVSVVDLTCRIEKPATYDQIKAAIKAASEGELKNILGYTEDEVVSTDFLHDARSSIFDANAGISLNDNFVKLVSWYDNEWGYSNRLVELALHMATVDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C662</accession>
    <name>A0A8K1C662_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="6">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 8">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C662"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="9">
        <location>
            <begin position="25"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6 7">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="33388" checksum="2800BB4D96B32403" modified="2022-08-03" version="1">MFARAPVKANVAQAARAMSASAKVWINKDTKVICQGFTGKQGTFHSEQAIAYGTNMVGGVTPKKGGSTHLGLPVFDTVAEAKKETGADASVIYVPPPFCAQAIIDAIEAEIPLVVAITEGIPQKDMVKVKWHLRQQNTTRLIGPNCPGIIKPGECKMGIMPGYIHQKGKIGIVSRSGTLTYEAVHQTTAAGLGQSTVIGIGGDPFNGTNFIDCLERFTNDPETEGIIMIGEIGGSAEEEAAEWLKAHGDPNKPVVSFIAGITAPPGRRMGHAGAIVSGGKGTAEGKFAALQDAGVTVTRSPARLGAMMLEQFQIRNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6G7</accession>
    <name>A0A8K1C6G7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6G7"/>
    <dbReference type="OrthoDB" id="5919228at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="179"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="46519" checksum="E57670D6AD2083CE" modified="2022-08-03" version="1">MESHPETHSVSAVAVIDLSDGAVGDPHGLLTSSVVVIGGEDGVMTSNGVGMLSHSSGAAGGSGGGLDATATSVDGEDDDEDDEDEDDEDDCGCGHPHGPEHAHPGSSTPSSTPGKRKRVVLSIHEKQQVLQRLDLGDQPVTIARDFGISRQQVSDIKKNKDRILAFCVDAKHLSTLRRKTLKATTEYHPGVEQELYRWLVRQRRLERAVTSEALNHKATDLFMQYAGDDTNSVSFRAVSVWLRHFKRAHGIKTLTEEELAKLPTKFTPAMDMTQSNDTPTGSSTSSVGMASPTASMGMALLHPTPNIHTPSAIDDVSSYINGMGMSSNTTPSAGSQYLLQHQSPPTLAETAGPNTFSMLMLSSATNTSTSSTISNAMASATALHASVSVVEAMTTQIAQFEQTVTAKLNQLEGRMEKIGYQAIAAVARTSSTQRMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6H3</accession>
    <name>A0A8K1C6H3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003236</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="6">
        <location>
            <begin position="1908"/>
            <end position="2497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1319"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1383"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2676"/>
            <end position="2710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2738"/>
            <end position="2757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1322"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1403"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2740"/>
            <end position="2750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3315" mass="371909" checksum="83EC1B2829ED14C2" modified="2022-08-03" version="1">MLEGPLKSWIVHFLGQYVESETILVSSKLWKSSERLKLENLTLKKSVIPGWLPFRLKTGFIGQFEVDLPISAIFGSGSAKIRFSDVLIVLAPIRHDEEEQREEEESLIDEKLDNLEQDLVDRWQGPRVPEYMVHHESEGYFGVDGWLGRTITKLIDNLQVDVRNLHIRIEGMWYPSSGPRSYTLSSRSTPGTKFAVGVSLGALSAVTTPSNWRIDGFDENKGANETEKKKNHLVFKLISAIDLSAYVDPTALHFIHSSIHPKVLHSTLSRLREMGAKNARADWWNIDENMHTHRFLIAPIAVSLKLTMNTAAQHAQTDDPRYDADFHLSKLTVSLDDEQLSILNLVLDSFNRHEEWRGKVSDHLKAQEKAVARDTGRMEGVIEEYAKLWKEITSMKTDDLDSVKQSAAWQRLVVIERDLPFELVVSLRNKSSTEAVAAGERVPYASLLHEMGDAMGIPLPEISVSFKEGPIGLILNILKDGNVEFVRSVENSQCSKKEAVKPGLLLIQVNGKPLKSAFRFRSALDVQLQLDSMPGARVLTFRYPLVKAPEVTPNRLVSRITLASDDLAFRLLRAEKKKVLAKLVLVHPVVGIRGYGPDLFLFHQYDCNVRAFYLQNNSYSDGQAAHCIASSVTPQSEEQVDYTIPAFRLGMDYLHEGHPDAVPGQVNTYGSKISVHIGNSVVAVDEPKLTKLMIEFYEFGGAISTQYTDRQTTDSYRTAGETLSMTSSGLLASSSSTSSAPEEEITTSSYSYDFKIDQVLLFVSAKKKTLPPKTPVSQPSYRTLLQQLVRRGSSVTHALPQDWARATQAIMIMQRFIRGAIVRRRRMMRMAMTRSRSRWIEYEGEDEEAMGWLYVRDDTLAFRRWRRSWCHIDEDGYFSVHTDGSGTELLDEFKTLGCTVTLVHNVHKGPWGLRAACSLLEIRSSSGEVRKVLSSEVVADLEKWRYYVETAARNAATRAAMGIRSRDRSESTITVDSLDFRNDGNGMPPPGQPGFALVEPKYSSTAAEQLLMGGFTDVYSTPTVLLKEKSSWISISITELQFWTDVHRVSVPEQTAFCLSLGVQYLSVTDHRKTTNHGLLHVGDEFLGLKNGVLIPARIRSDRVKGGPFLAVDMTYRGAQASSTCFVLKDGLSIDLSVCGWFLPLSLYEVLFEVIDGLSVLWTDPTVVNRPTEAPSDLANVPAMYEVSALEIHVNAPIIEAYLEDVHCVAKLSLEKSTFGYKADAFRENAKLRLGPTALFVLTDEVALRLAQVEKCWMDYDLRLHRPGAEHQVRCELCADDKVRRSHRSIAISIGQVKLEADRRLELLFALLEALTSSEESAATDEPDDEDEYLMSSNKEDKRLPRMHSAPKMYEVHALSMDHLPTERMQSMQFTLDDPDLRPMYDHFGHNAGPNSPADRSRMSSASTAHNWQSQDNGQTNRSKPRSVASAWIPLLNYQAYIAILPSESQPRSRTLYRIRLRVGRVHDRVSLACTSIVFEVIKRSLSVVALDTYIPVMNFSVSDIKVQVLTRTEFTVDRALDASAQMSARYYNSVLADWEPFIEPWRAYARVKGDESEGGTSVELSAMERLNVNVTDALVRLLTSVAESRKKQVMYVEKRTPAAVAADGEAKKEDGRVCVLNNLGVPIRLANLNTSQPGTLYVEIRDGWSYPGYSRFHDVRVEVVMLPWWHPREAQRVESLRHKFSLPYGGAQSGVTPILRVDVSTFGTGKRNFVFDQITNRYVEVDDSEHEESSVLSAQKSVPLLSQMLREVSSGTAKAKWTSLGTAEINLVGSVMGSLGSRGRKLNRWYRLHDSRGAVTGEISVMLEFVPHEPSSGDLDTKVHEPDQVKDGQFLVFDPLKIIGGKESKQLRRTKSRQQSSKHIVLSHGLKASYVPPLALEVSIGSERCSLLCPLRRAGKFLIQGERVLAEVKVAQRDESRRVLLLSSPVQLKNDTSVEMDLWSCPTELNVGEHGSFTHGNRLSLVSTSKKISVPLSAMYGEEKHAIIVKVEGCKPTVVAKLGTLAPGSSIIPLAPDDGLVLGYCLFVNVNSYMRKVYREEHQEIVTRGGAAGATEGESQSYATTYQIGLHSCLLLGNTLPIRVQFRVTVPSDGTHPEQTLRTGTVSPGEDVQLHEFHPKAQLSLRLPEMDSIWSLPLQLGDCIYREGMDKSVKSMLGATGSWLPTIDFIPSIQTSGTSFKMEDTESRRVVARLDYTTATDGIPRVVLYSSLWIYNQSHVPNLLFRCADDHTQPIVAVPQLVPQRPVPKLMDCPGQVFDISTIVDHEVARWSEKIHTTVVGVQGPIALKFGTLGPRTRNEIGISIKRPLGKFHRTTQVIVTSRFVFVNRTQTAFKVSSYGRDSENVIEVPPALGGVPSSTPFDFDGGSNAVNRLLYLRMDHYGADWSGPFSVDEDKEFPLRLKGEVEARWNDKSKDDRYSHGGFRRGGANMNRVRIRIHTVGPTMVVSLMRDDPPMFLIRNESSLDLYVNQHKSSEDQTIIRSKEFVPFAWKKPEASRRVACRVGIPGQNHPKGFGSRVYDFNNLDREKGFEEIKYWVYGNQLRRISADIAVEESSRVLVFRDQNRERPPNYVLEVKVIATRFYQELSTRDDTSAEIILETDNDEPKWIPSKELKTSHVYRFDADKEFSTETRPKRLVLSVFQNRQGREDPSESISIGMENDSMLTAENVADVLEPRSPMAGGDGSGPFEEIATPIASPHSQPINSDRPRLERNSSLYRFDNASLQDAPGLRFMDEDQVSNSDASSNRSEIAENADERLRQASGVVEIKIPRKAWSKFGVGMRRSVAWSNNNMGQALLSMGRLEGHWWEMRDPESGELVGEVQVALKFRTAVKEYANPSVVYNLSVRIPSVGFSFLHSANSSLVEVAYLSLQRLGMVYSCVGDSSEIACSLGNLQMDNQMDAEVVLGPKVHRVKEGVSVRLRDRWHSFRNYRYRGIYEQLDTRNLSFIQFRMLWNSRCMAGDITHYELVEFAMHELEVSTDEKFVVNLITVFQGLGKLSSQQTFDDIVNTQLDYCGPTVEGEDEQAAIADGVYIEELDIDAIRVTFSMELNGGRHIKTLGPSGRRLAVYLPESNVKDFRLYFSNVTYSHLYESKASVMDKVIRRYQQQTVMLVLRGLHTVSVYANPIRIVYRMGHGVLEVVRLPARGLASGSPVELISGAYLGVRSLAMNTISAGYEILAGITGILAASIAPLIPESRRRGFEEEMHGFQRAVIEEVDSFDAAEERTMTKVIVRKPRVFDDQGVGLLTVYGPGSVPLEDQDRINNRAVVLLQQWWRRRRRASILYAEALRLRPDLAQSDPNNSSFVSRMECAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6K7</accession>
    <name>A0A8K1C6K7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA polymerase III RPC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6K7"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="37974" checksum="43B13B6B4D487840" modified="2022-08-03" version="1">MAERNDEMMRTRIDASSSRLTSLRTATADATAAAARRPKFVPKAARRRSTADGEGGEEGAPAASSERPQPGQHKPAHRAGDLTRDRGRGGRGSADGRGRGRGRGRGANLPQGRVTFVGTLSGGSSFSSGGSTAPRASAPAKPVAAADGVGISVLDDEDGTLQDEFNGMEIEEQWPPTMKSVMEPMTLSFARRPEPSNSGAIFCDESGQIVLPNDTLLYLQLPTTLPLASATRVGTPADEAKEPETKPVNKFAVASEAVDAPVKKEEELTEEVSIDRSEDQIYDKSIATAPGGFVGKLVIHRSGKTVLMLGDKKFDVAAAHTPAFTEEVYSIDSTEQQLCMLGSVDRHLVVTPDFDALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Y4</accession>
    <name>A0A8K1C6Y4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Y4"/>
    <dbReference type="OrthoDB" id="57945at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42883">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42883:SF2">
        <property type="entry name" value="THYMIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="51992" checksum="0C242572C8FD6179" modified="2022-08-03" version="1">MRTPSELGWSALLLSCMGISALASTAITLALAQLNSPKRTESIEVLVEPPRAPKDEEQVESSEPPKTEQPTRALPVLDIQALSVVDVPENLRLEAFFSPQHMRSFDHSAIFTGCTNVFALIDAIHPYLLTFFSESSWLQSASESMRATILRASAKRDAHGRYVAESDDDDDDEDDRSAARRLQQWRLPTCIDPNEATEFVIYPGVDPRTFLPEKVINLDPNAPVRPPKSPHSAVARRYSNGRASSFVLDDPDHPEPQKKHIVVLPGALVLGGTFDVSEGSIHIGRNVRIEPNVYVKGPCIIGDHSTLRSGAYLRGDIIVGRHVVLRGEVKNALIMDHAELCHPGYCGDSVCGYKSHFGNQVTTANLNLFSNSGLQEIVVQSGNARYNTRRKKIGVILGDYAQLGCSSVTDPCTLIQRETVVYPLTRLPKGIYGPDVIIKNKPLERGVLEIVPIVRKEKESTEEKVESVMAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C869</accession>
    <name>A0A8K1C869_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C869"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="792" mass="88967" checksum="1F3D3663E5F65670" modified="2022-08-03" version="1">MGPDAAFVNQDLKAPVHPIVAIDKRLCHDRPISLMIPQDILQHPKNGAIYEVAKNEFGKHGVGMNNKHKDDKNPHDPNHGAVHNMANKATGHDKYGQNEIRHNELPLGGAHGYHGTQAVGQNQDGYDKNQHTDVRNAIHDAAHPTSQNEYGQNQYGQNQYGQTQDNYDPNQHTGVRNAIHDAAHPTSQNEYGQNQYGQNQDNYDPNQHTEARNMMHDAAHPTSQNQYGQNQYGQNQYGQNQDNYDPNQHTEARNMMHDAAHPTSQNQYGQNQYGQNQYGQNQEGYDPSQHTEARNMMHDAAHPTSQNQYGQNQYGQNQYGQTQDNYDPNQHTGVRNAIHDAAHPTSQNQYGQTQYGQNQDNYDPNQHTEARNMMHDAAHPTSQNEYGQNQYGQNQYGQNQEGYDPSQHTEARNMMHDAAHPTSQNQYGQNQYGQNQYGQTQDNYDPNQHTGVRNAIHDAAHPTSQNQYGQTQYGQNQDNYDPNQHTEARNMMHDAAHPTSQNQYGQNQYGQTQYGQNQEGYDPNQHTGVRNAIHDAAHPTDQNQYGRNETHTQHGATHGIGQNKLGHNEIGHNKHGIGNNPGKHGKGALMFDLASMPLNDRDDRVLKDSNGKPIAYLTEKNRIIQRNFVITRDPEGQDAIFDVKRKHLSKSPVRADFKDLASGRMCRLGAAVLEETHGITALLWLDNGDGTKEKRPVGRLHLPPGSNRDPNVMRATEDHHKMTDALRPVTKQQNRDADGRRSKDYQLDLMPGIDAGLAVLVAMVTAACTDHKRATDPNTHSSVTPVKHSNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C944</accession>
    <name>A0A8K1C944_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C944"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="25344" checksum="C4655292FBC7F218" modified="2022-08-03" version="1">MTNRERAKYYRDKNREYDRNLTETVADLQEQARQLCWKAQILQKLTSQEVPCGVSDKILTQLTPLMTQPDELHLYGFKNESVEYQGAWMLGDADAPVVALRLLARGQYTKAAIEQVYQQIPGRKDILEQLLHNPVEYACIVRFFFTSVGECVDRELEVDWVSGLLRCLGCLEHVDRVVEYLRGSSAQDDTVECDNSSNASNDDRASHSGMSPMELEYILSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9R5</accession>
    <name>A0A8K1C9R5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9R5"/>
    <dbReference type="OrthoDB" id="167464at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51705" checksum="E51201B6A954DDE5" modified="2022-08-03" version="1">MEDAKDWFHDAIYADSDDEAAALVHVIGKSRGDDEPVDAKDDKSATDGGEDPYAALSPRTRRKRKNRDQMRAARQRERETMDRLRRTVERLEVRYQEMQHQKEHQDVPERTLAPPVATSNNAHEPQAYVELLAVSSQLKEENFHLKQTLHEKHKLQETLERVVTDHTESTRDTQELLRLSDQFQGSTAIASTPAKTLSGEDAPGSHWADSFNEIPEEEIWKRIAGMHQEMAHLRGSMRDRTTSATIVVDDGRSSMSPLSEDDLSSSGTESPSPSAPLPSFCGWDVRHRIQGTGLFFTFEKAFTHMTAYNAMDRMWLNERGMQSYRDRQNLATQSLHIVQNVNDDTYIFQRRMLHPSTRRPVITTYLRFRQTSPQGFIIGSTSINDLQDAAVWAAQLLLWTEFIPLAGNGGCIVRMTGRTNLDSPANAHRYVAEVIVSLLRWENLNIGPMFTLTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAQ0</accession>
    <name>A0A8K1CAQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAQ0"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF28">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="113"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="515" mass="59241" checksum="C123DF789E7B3791" modified="2022-08-03" version="1">MAQWRRVTRTLGAASAVGALGYTVDESNSHILSRSLRVFSTGIQVAVDFRQNLKPIERDAPEYKSALQAFNLRTASRLLDVCFQNGGIYTKFGQQLSTFNHALPREFTDTMAKLQDQAKSVSFEEAMATVEQELQRPWREVFPEINETPLAAASLAQVHEATDYKGRRVAVKVQYPHLARQMTADLVVMRWAFELTEWFFPNVQITWMFPEFQAALESELNFVNEKQNSRRIAELMRHNPNVHVPIVYDDISSKRLLVMEFIDAPKISNVEKLKEESIDPSEVARVLCEVFGEMVFCHGFVHCDPHPGNIFVRKNPNANATSKSQLVLLDHGLYRHLDEDFRKTYCDLWRAMILRDSDLLQDCGRRLNAGPFTTYLPLLFTYRPLGSNTPLASKMSLDEREKLTEELRKLQVTDVNGFIQHLPRDMLFVFRTNNMIRALNKDLGGSTRDRFASMAHFAVEGHALYHGATAQQHMSSWLVYYWDRVNMILHLRVFDWALRAIQLVRGEQVTDHRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAX8</accession>
    <name>A0A8K1CAX8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAX8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="372" mass="41168" checksum="12BFDC429B43E720" modified="2022-08-03" version="1">MLDGVVDILAQLQKMEEHGTRLRSNELDENIRRVYELRNQLERYMTRNVVAKAFRQSKTRMYLSDLETTLESLATLHEGLCQHKTEENLRRLNVLAQSLCEAMEEMAVDHDFELSVSSPSVAPSHSFKATPRAPKVKSIMMSTFSRFNAAAFASVSQPEHADLNLNVSTNQGGDSDQQITMQYVEMLESGGDNEKSEALWSLNQISKHTSCTMNASRVAAALVAAMKHSSTLHRLLATRVLRNLAKIALVDEDVLCAQAIPALLDSLDAHNDRVILEATSTLLVLAQSCTLQTEIVAAGGLEKLVTIAKQPRWGRVTATVLAALCALSAPISVLDNVEHPEHKFGLQSHLAGLEDRRKLMQKRKPEAPPKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB08</accession>
    <name>A0A8K1CB08_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007272</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB08"/>
    <dbReference type="OrthoDB" id="103326at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF2">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="493" mass="54191" checksum="CAF14D032447A9DE" modified="2022-08-03" version="1">MRTKSGYPQHIQHDDATTFIDVEKIDMILESPHGAFKDVFAPEISQPPTYRVVGTLGMVSIVYLFTCGGPIGSEPIVSAGGPLVGMICLLLYPFLVTIPYAYIVAELCSAFPEDGGFTIWVLNAFGPYWGFQVGYWSWISGVVRTALIPETILDLFLSFYDMEIESKAMRFFVKAGMAIVLTVPACFGTKNVARLSCLLLVVVIVPFLTYTVWAYTGARDFDDLFQVRHETTVYDRERADVETEGSIEIDWTVLVNTLFHKFDGIYMASVFGGEVMNPARTYPRAIFFTVLLAVATYLVPIPASIVADDLSWVFFGRDAYPFMAERIGGSFLKTFILIASVGGALGTFISGIYLKAFQVSGMAVNRLLPSILARRRSRFESPNHAIIGTAIVTIALLPVSFDDLLHMSNAFAAAVEFTIIVAAMRLRMTLPYIPRPTKVPGGVPGLLMFAAVPGVVLGYILVHTFMTSLIATLLMVGLLAVGLVYGVWSTRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB45</accession>
    <name>A0A8K1CB45_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB45"/>
    <dbReference type="OrthoDB" id="173909at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="701" mass="79227" checksum="6EB03907ACCEF789" modified="2022-08-03" version="1">MKLNSKLLSIAGMISITILLAIMDLKDIFYKISMCGPRQTFSFLLQTPEVVTNFDLTKAIKDANGTWLSAVNQWNALALQCDALYPSQLPGKPAHLSSLGIGCILDGVKRPEEIMFVGAHRLDTFLWATGILADLVDEPLPVPPYTNGMYAAFFNLDERSYRRQLAAMIQLEDIPNIKANVKEIAATFATRTSLWEKALCYEMTPMVGPGEFKTQVEAIEHGCISTDMATGETVSFHLEPTTGKYYRFLSNMMGLQWHTMDYLTIGNNIFLRARLYMKTFYQLQHTSDGQRFFWHYNQSDLGVDGALYVLLMINEIVIVFINATDVGIVAMIVLRPLVNTTKSSSVYSTTDSTSTVANNTGDSKRDGESAKERAPATQKNSDKDSTLAKMLLYTDLTSVSYRKPLLSTLLAADALLAWLYVVPNSNAFAWGSSVWQVGSAYLSMFRVWVIVLIVIDNGWKLTVVLLNERLAAIITEFTYITSFEIMCSTLLGIYLTFDDIMNICVLKYGLVDGQRAFTPTTPTIFSFYNSYTTYSYGDRSDDRDALFYIYNPLAKIMSYGILFSFIIVCVRLIYTTVRKHVKGTLAGEVETFWRTYQRNSAEVFMDTPMRANALIRSQQIMSYRFGKSVFIRPFVYLEQNFYITRGKFRARPAIPFLMNEDAEVGADVDTKSYMLEGVFRSENSTKLQKKHRGHDVQIPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB72</accession>
    <name>A0A8K1CB72_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB72"/>
    <dbReference type="OrthoDB" id="115707at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474936" description="Serine protease" evidence="3">
        <location>
            <begin position="21"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="46844" checksum="01675B8AAB60971D" modified="2022-08-03" version="1">MLSRLLRWYTLLYSTGFVLGLHAQSSPQDIPLQVGAGCEFSDYTTLPSSSSSQNETPSFRFLYDAGLGKGLYVVHFSRFNLPPDDTLSIRPKSADKSSPLTQVMTGANTTGSFYAAPILGDGLVIELYKKTNISSSASSASGDCTGFGVDGLRFTAASEAEATALGGEASIVALSSKPEGNSEDKKKEDKGADESLCGQDESQEAVCLETSTTATGVSMYQASRAVARLEISKDNGFNIAYCTGFLLGCEGHLITNQHCIRDWIDALNTAVEFFAEASHCSASETCQSRAACPGRVRIRSTALVAVSTTLDYALVKITPDDGSPIESLLSQVGYLQLRASGPKLDEEIYIPQYPLGWGKRIASTASGQPGRIASLSVDRCGGKDAGYYVDTQEGSSGSPVIATADNTVVALHHCGGCLNGAIQSQQLIEDLQVKGVLPRCSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBG8</accession>
    <name>A0A8K1CBG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBG8"/>
    <dbReference type="OrthoDB" id="62890at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="216"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="50672" checksum="D88471A84194270B" modified="2022-08-03" version="1">MRTAFGEYEDPALCTKTATDKGLDMVYAAVRTATMVTKKTTKKNDKEEEEENESERLELEAARRFASLRETRPRRYSRPTEKESVKPTTVTTTSSSENQEPVFENQMKEQKKVVEEEDDDELPIEAARRHAAARAALLQDHPHQPHLRDPFDPRLSSSAPRHHHQHQIHHRHPSRTSSRRPASAPSSSSKTARKHGSKRPHDGNTRRLCNYLLHSVTPRESSIFDYSSFASPGTHTEYDIVIENIRSSEIWQVSRRYSTFRDLRKELDALFTQPHCHHCTHFHDTLLDLGDIFPNKRLWGSNKRSVVVSRAERFHRYLKGLLDLGARAHQQSCQLVSGAYVVHLTTFLTVDAEQFKGIPGQFGQDVPSLLKELSIAPRNPREKAQLATIMENGGVANAAALAILEEAEDDTEDEDDEVRGPLVSKNSVLEQKQPASARSARGSLNGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBH6</accession>
    <name>A0A8K1CBH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBH6"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000412">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23555" checksum="708ACAC3C9BF3FB0" modified="2022-08-03" version="1">MGAVFSTYLRSLYARWMRFRHRKSKILILGIDAAGKTTLLYQLKLGESVRTIATVGFNVETFEHHNISFTAWDVGGSAGLRPLWRHYFQETDAVVFVVDSADRERMNEAKEALHGILNDSTLVNAKLLVYANKQDLPNAMTPQEVTQELELDELMKRRAERGSNGSSIVYHVQPAVATKGTGLVEGLDWIYEALLGVKVEEDEDELKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBH8</accession>
    <name>A0A8K1CBH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBH8"/>
    <dbReference type="OrthoDB" id="183992at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="887" mass="100534" checksum="9338B1F2092E9C62" modified="2022-08-03" version="1">MSPFTASNTRLDILRTFDFIASLLCKCLCYEDKFSLLVSAYDLGLEELIRYLEYEDETSVFPRDLVLEVAAAHGCVYALHRLLRPTDLRAFPGLEDSTKKYSPRVWTELTRVMQWLNLYRPAVYSGEAMIHAAIRGDMEAVEWLHSTSAYDIETALSVAVKHGNFDVVEWLVAHQSTALHRLKDHKGGPKKQVEVVVGTNHALFQQRLFHWVVRLGGLTTRWFGLRRRVDGIETFTVREFVDRWRATLTHSAAVMDPLCFAVSLGETELAKSIYEDESLRPDHSEAIAVAAQRGDVDLMDWLRNACDYTIPPHTLDVATCEGHANVVEWLENSGGTPIDIPRVLDMASQHGRLSLVQRMCERIPTWKFQVPRTMVLADPKLSARFRDVLDWLHDEDKLVEDANVLSLAVECGANRVVKARVDAKTVEWHRARYFLRTASQKGQLAVMQSLLEARPDGQPLDSNCLRNPFLDALTSGHRDVAEFILTNYPEQCSARGHHLLSLVCHGRMDMAKMIYDPDDLVNIYAWESQVKESFALFQPRYRLRYLLLVDNIHVKHQLTHDSGRREFVQWCLSDRLFRDTEYRFVAQWAVQIGDLDLVREIIALGVDPEIGYKDVDANNREVLGSVTTHTKASDIVCTILRQSPSLIGKDVVEWAAKHRRMKVLECIEELIAEGPKSLVNRLVLGDRRIMLHSAIVAACEHGHVEVLEWARHSCGSLLENRRHKTSPSGAAPATDKTVKEGAEETGVTSEKLVIHSVDPWRRAARTAEEFGHLHVLKWLDAQGMDSDRGVRGYDPFANGAYRHGHLAVVIWLWEKHMANLKVPVGEKSSRAFKRGLRHAIEYGHTDLTAWMIETAASIPLLALDADLLMAAEKAARKHGVHKSREVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU8</accession>
    <name>A0A8K1CCU8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCU8"/>
    <dbReference type="OrthoDB" id="329563at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000018">
        <property type="entry name" value="Cell division cycle protein 27 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="537"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="639"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="694" mass="79002" checksum="38466232FADE0093" modified="2022-08-03" version="1">MKTMSMRSTRAEFATMPSVYTVDVLEETLNERIQHYLELHLHDNAIFLAERLVAHNRAEENLLQLATCYYRAGKVARAIAVLENAKRPENRYLLALCCFQQNKLVEAENALQSGESRPYMGNTISIENVPNGAAGMYLMGRICRRANRRQQAIDYFTKALEMDATLWSAYEELCDLGANIDSVKFFTAVPMLSDDFSSGPEDDFPVDNSKADGNSAYRTPQFRTPSTPRDTLARLSGTRHAVSTPAPLSYRTPNAANNYSTPAFGSPQEVVKKSRIGGINGAPNPRARKTYRRPLTETDEKQRRNARLSFSSAISEDSPQDFSKGDSGITPLATRLFQSNNSPAGSPKSKPTSQRKAHEGRTQLLQLLSAFGAIYQKNSVYMCREALELLDRLPKNQLSSGWAQLQIGRAHFELADYKQAQYVFRALYQGEQYRMAGLDLYSTTLWHLKKEVGLSYLAQQVTEFDKLSPEAWCVAGNCFSLQKEHDTALSFFQRSIQLDPYYTYAYTLSGHEYVANEDFEKAINCYRHAIRVDPRHYNAWYGLGTIYYRQEKFEFAEYHFRRALEINPRSSLLHCFLGMVLHSMQQFDEALDALAIASELQPLNPQARFQRANVLITLHRYDEAMEELNAVRNFAPRESSVHFMMGRVAKKLGRVDEAMRCFTTALYFHPKDNNIIKSAIDKINEPDLDDDDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCW6</accession>
    <name>A0A8K1CCW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCW6"/>
    <dbReference type="OrthoDB" id="514832at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33629" checksum="81DA1E74B6122C38" modified="2022-08-03" version="1">MATITEDVLRKELRGILPGMDPTSVTVLILREKLASRLGVSGAELKDQWGKTIKKLIPEVMQVMRDDSDKENEAASESEEEEVKRPRKGISTIKKRGRNAIQDSDESEESEGSDESDNDRGSEESGDSDNEVPARKRQRAAPKAKPKATPKPKPAASKPVKGSVGFESLKELARVAGLLAPNVYKLLKGAKNEQEQEQILRDRLDNAGVRFSGTYPSRHDIAEAKKKREKAQELDGIDTSLIIDAPRSRRATPLRPDIRYGNDRDEEEDDEPAPMTDRLQDESEEKESSEAEFDGESSDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDS9</accession>
    <name>A0A8K1CDS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000977</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDS9"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="6">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="97" mass="11506" checksum="4877BEB52F724568" modified="2022-08-03" version="1">MLVTILVVWGYTRLYVYPFETLACIFKEMPRNNPNLSPLYFWSLKVMVCFLVVLQTWWLVLFAEKGRRKLLKTNGYVEIPQKAWLASHNESHVEARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE88</accession>
    <name>A0A8K1CE88_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE88"/>
    <dbReference type="OrthoDB" id="65522at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF3">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="40206" checksum="C77644252F704AD5" modified="2022-08-03" version="1">MNSYSSSDGNVNIRPAGSGPIKPDVPLSINTSHSYSDAAGHSHETSYRLHVGSEKSDVSDMSGEANLEDSGVDDLGRSKKSPGKRSRAVKNPNRSTKSKARPGLRKGKWTEEEERYATQLTTYFKEGLLPIERGTMLRLYLSQKLNCEPMRITKKFTGGECIGKQVFRPCSPTPESRVRLMQAQLELVALEAAFIKKLKENKEEVPGLTDDTDGSVVTGGMPPGVNQKKRRSRGQRADDDAGFSSDSSSSSDTTISSSHTVDMKRNVDGLDDASAVGLLLDFFYKASRKENDSDTSSSKDGNDASGKTVSSPVAEPDPETDDYVGPMKSANEELASSPIKRMRTLSISNCVTDVTSPKRSRVGSFTIMASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFJ9</accession>
    <name>A0A8K1CFJ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFJ9"/>
    <dbReference type="OrthoDB" id="118200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="28162" checksum="A2C4BA453C7A3864" modified="2022-08-03" version="1">MASSTSGSSSVDGFLRSPNACTYYDVLDTDMCFVPRACAACLEMEGCMVNQFGKCVDAIAADGYSPAMNFRKAQELNLVFPAAADTNASTEQRWQFPALNATYCNISDAVCNECRQKRYWMPRHSGLDARYCMGEAGCICISMCDSPVWEEAIPKQCIPGLQPSHSVKSSGPSVGGILLAILPTALIISGCVYCVRRCRRKKRAKKEEEERDEEPATPVPGTTAQKQETVPYISIKDTKEEVASAQHPTVSDEVASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFP9</accession>
    <name>A0A8K1CFP9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFP9"/>
    <dbReference type="OrthoDB" id="166332at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="37872" checksum="C5233369424BC6D4" modified="2022-08-03" version="1">MSSEWSWRHPASNELVPSSKRSGKAPRKKCTQHPKPVKRLRLAAREREDLRLYNLTLDINDLRQQIQDLAVRKSLVETRAVYTRFDPNGSIIKTLEEYVRNFTEGFRGTNPVQTAFIDWVCDPCFQIGNNPADDINMLLTQWLRYTELFHVQSFTLTSARIASRDVDQSSVVRCSTRMRGVFTLKALATVFPRSLKEPAIHSRLLGRDWNCDMSFYFHFAPDGKLKRLDPEIDFFTAVNRVLKDTRVTALIMNDAILSQDNHFVGEVVIPEEDDVLMCDDAEPQLESRGPSKVSIFVESRRSHSIDNQVEMRPPSPAVNSPRLSIDYLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT8</accession>
    <name>A0A8K1CFT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005324</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="55162" checksum="CB98F07FB31B7481" modified="2022-08-03" version="1">MPIVAKWTLPILHNTIEFVSRTSDFHDWLMSMCQQYQGKSFVLRVLGQPDIVVLCTPESVEDVMKTHFESFPKGDTVYEAMGDMFGGGLFASDGDQWAHQRKVASNLFTARKLRETMTESIRKHTIVLRRMLEEAAGQDKTVDLFKLFNRFTIEAFAEIGFGIRMNSMESADEHPFQTAFDRVQRATVLRFVRPSWFWKLQRLVQVGVERQLRQDINTIDGTVLDIISQSIQRRQLGENQRDGADLVSLVLDYNEKTPEAKSGEFDPHYLRDIVVNFLIAGRDTTAQALSWFFKNVGTHPEVVTKIRAEIKHVLPGLMDGSIETPTMEQVQQLTFLEAAIKESLRLYPAVPVSFRVAANDVVLSDGTFIRKGQSVAVPVYGCSRMNYLWGPDAASYNPERWFDPVSGKLIHFPSHKFFAFSAGPRVCLGMNLALLELKIVLASLLSRLDVEVLEPGNVTYDFSLTLPVRGELLGRISLHIAQTEKANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFZ6</accession>
    <name>A0A8K1CFZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFZ6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="89" mass="10346" checksum="E9312C754FDFCEFF" modified="2022-08-03" version="1">MMSLYEVLSGYGRRDVGEQLWFIATEEGPAQVRVYRFNTDGEARLAMGEYRCCRVLYSPEGIEKHSRGWNGMALATIRHVMNENYLAWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG46</accession>
    <name>A0A8K1CG46_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG46"/>
    <dbReference type="OrthoDB" id="70901at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="470" mass="52592" checksum="8ABA4568E1B5FFCC" modified="2022-08-03" version="1">MATTASTPSTRQFGIWRSRIHRECEKCASVDAIYAGVTFHELYVDEERGIARARFHCFVPFREGSSALAMVPLVALEVSMPYDQSQLANGEAQFPFQAPRVEIYKGFEYLPREMRETEAATGAVLLRITALTHWTPSNTLMMILQDFVETVQLNDPQPTAAASEGGASPVGGHAAAGRNGKRLRLRKRDIHGVVYNCQEVDTRTGTLCSVPLLLQSGNVVFLAPPSKPSRATAASHKDDEYIFVNDLVPLKEIARITPQRGKSITFFFKSRNAHCRTLLTRQTEEIIADIQRMIAAVGSKRSREDDSRNGYHRNSGPSHDPNDSGALSHLLSFLTPEQTEKAKEVSNKIVGKLSRWGSSVSRFLRGDDEHESAQHHHQQTRHEANDPALREIDQLKAQFFRYPSKAKMIEITNRYQQLAESHAHRGSRDGRVEKAVEELQSFIEHPTSQRVLLEDYAAEAPNRGIRVGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGG2</accession>
    <name>A0A8K1CGG2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGG2"/>
    <dbReference type="OrthoDB" id="161023at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019188">
        <property type="entry name" value="SNAPC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131">
        <property type="entry name" value="SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131:SF3">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09808">
        <property type="entry name" value="SNAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="670"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="734" mass="78720" checksum="53257BC0BE92D7AD" modified="2022-08-03" version="1">MARDASSARPPLPRRRPAQDAGVADGEGVRVSAPPKTQALAAFARCVEAELRELVEVFVGIENVSFAEFKRLWAELRVGALFHVEFRDSTPTDTHRIILQQALALVVDAVALDHDQDDDIAQVLGFGFALYAAFSVQLSEPRHKIAVTPTSWQALVELSTLATQALGHVDEAIARAAAEMLAMLRQMQADDGFLRCLSGEVGEYNVVIQRKGTVASRVGLQQTIPSRVASTEADYALDDTLARLEALNTQYVARMEALTAAQTGPQHTVNAARANSSRGRAAPSFLRSTRRAETTANSARLGSLTTVWTEERSTASSSWLKRLRSAFEPPQAPAIDHSQDRSDSFSVLNSSDGASSDVDAALLALEAELERDVVPSAPSPEVVPVAVPTPRRLPIANRSTFRRGSMSIASSGQESDGLAELEEELAMEVGQRGQALAPAQPSTAVLPAAPRRSVRPRALSVAESARSSVFDSGDELLELQRELEAAVAEPRSVPIREPPKTTQPTRKRAAPTQRAKAPAKRATPVVAVPQPQPKAVEPPRRSRRLSIVSSAATESDAELAELQTELLRDTVVPLATGTSIGLPSAPLRRLRGPSISSVATESDAELNELLFELNTTVAARPPPAKPRRQATAKPKTTKPKATAPAKRQVREKSTKPRETKPRAPAKKKAAPTTTRMPTAKRSTVPMASTAPPESRPIAPPASRLPSSRRSIVSSYDGESDGLAELEMELNASIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHW1</accession>
    <name>A0A8K1CHW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHW1"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="121"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="204"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="303" mass="35298" checksum="5310BA80E471EB38" modified="2022-08-03" version="1">MKSKNARLLSAFDAKLDWRDEIQGAMSKIYVGNVAFDHDPQDFEALFAKFGPISQCAAKRGFAFIHYENADDAAAAVKDMDGQEWHGRRLRVAFSTSSGSNGERSTRESTRDEGRNATVSRNLFVANISPEVKLSELEEFFEQYGRVENVKILPQARGNVSMSAFVDFEDIAAAEKAFASELVLAGQRLRTDYNIRKDMRRQDDFDSRDRRYDSRDRDHRDDMRGRRDSYDERSSYHSRPRPRSRSRSREGRNGRSDRYSTRPAYDRDAGYRDSPRRMDRDRGYTRRSPSPRRDYRDRSPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI17</accession>
    <name>A0A8K1CI17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">Poli38472_002728</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI17"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000104">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000071">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 21 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="18" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 21 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 22" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="4"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="294"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="TMW63787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="482" mass="53129" checksum="BE701636AACB94F3" modified="2022-08-03" version="1">MNRYKVTKQLGDGTYGSVLKAVNRQSGEVVAVKKMKKKFYSWEECMQLREVMSLKKLNHPNIIKLKEVIRENDELYFVFEYMENNLYECMKKRDRHFPESKIRNLMYQMLQGLAFMHKHSFFHRDIKPENMLVKGDIVKVADFGLAREIRSRPPFTDYVSTRWYRAPEVLLRSTTYNSPIDTWAMGCIMAEMFTLRPLFPGSSEGDQLYKICSVLGSPTHATWPEGMKLAAQMNYRFPQFVPTPLNQLIPHASPEAIQLMTDLLKYDPNQRPTSSQALQYPFFQVNLNISMPLTCSTPNGRPERESDSYAPEKTASFTPPAEKGSSSGSNGYSTKNQSFADSGYGGLRQAVPAGAAAATGGYGGSSMMYGASRPPQPRNAMAAIGSTLLSGGTPQNSAGRGLDSGGLSNDVAGSRYTRQARYAPGMGGHAADDDKYSSTLRSYVNTNSSVAPSAGTRVPLNAGSTTSVGVAGGLGGYSRHNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI84</accession>
    <name>A0A8K1CI84_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI84"/>
    <dbReference type="OrthoDB" id="162247at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="50663" checksum="FE1DA41B1F40D613" modified="2022-08-03" version="1">MGLDAMGNAVRKLPAWPLARPKAIPRVFTLSYERPYTHHMAQPLQVRDATLAFAGQSPDRVDQWTTMGRETTPSSTPPRFLYGGQVVAGIGAKLNAKEAKRARRTEIEKRSRQRRQGTVSVMREELAKLERQFRLLSSQKDNDLYGAIILPSEVATLKERYLALSREATELREESKQLMTVLHEKQLFTDAMRSMLLEYASDDSRTPWDSMYQSLYEPMDIDECFRQMRDVYDTIERFESRDDFLTSGASVLGWNDKRRLEPDQGVMYFSFSKRFPDQESTRLMYESWDMFCNEVAMRKTIFPTGVDVTLETLQVLSDDIVVMRRRTHYTALQRSFQTVYLLFRVLTDTGYMIGFRTIPSPGIQSALEENESWIEVFHWIQVTRVQDNSEDPVQVQVSFGGSIGGSVIKFALHWMIELIMTVVRWENECIAPIFLTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIA9</accession>
    <name>A0A8K1CIA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polycystin cation channel PKD1/PKD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014206</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIA9"/>
    <dbReference type="OrthoDB" id="444119at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF183">
        <property type="entry name" value="AT14535P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="6">
        <location>
            <begin position="361"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="524" mass="58941" checksum="BFAFE2088BA57645" modified="2022-08-03" version="1">MASEQKSKVAVLKTPQDEEITISYQDALGTLRHDRHMKRAILGIPFPVVYFCLFVAMLFQHVPTESLYQQAFSVSSVLDSTGTDASTTDTTMKYENIQTISDVFDWLTNTFVPNVFITTDYNNDTLTQDKWGRIAMFNKVLGAVNLETTTAKIHPCQAQPFLTTLYPQCYDAANVNTSNVLISFDTSAYEATDVIARLKARGDWLDFATQQLVITVVTYNGELQGYTVSKLQLDFHQGGYIELSSTITPTISDPYKKTAAITLDVLVGICFLATILDPAWHFVKAIRQDGRHFLRKIESWGLVDLCSTGFVAAFYGLWFSMVAMMYTKEFRENLARLVVSGKTFDANSDERLGLLAVTDALEEVANITIAMRLLAMLSVFALGAQILTQFRFHPRLNILTRTIANALHQFAAFFVVFIVIFMTFSVSGMVLFGDRVEDFSTLPRTFEACINMLFGNFDYSIIRNLQAPVGMLYYWAYMVVVCLVLLNMMLAIVLDSYAEVTEQSAKIKRSASFRRTLENIINTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIY0</accession>
    <name>A0A8K1CIY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIY0"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="174"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="2">
        <location>
            <begin position="933"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1174" mass="134683" checksum="B3318AAB8375E26D" modified="2022-08-03" version="1">MDATSWVEVVSDAYDAALGHRQRGEYWQAREYFEVILQMKANVSSDGYERERIERLQTWTHYHFADLLLRNPQDSGQYDMRKAREHYQAALDGDKELHVFGLVEIFHCYNSMGTLSIDLGEFVKAERYLRTVIDVDPTAVEPLGNLAMLFNHQGRLDEALYFNTKAINLRPRDFRLLHNMGVTYELLNQEDRAREYWERALSIKPDSVETLISLSHLFGERGDTERAKSLIARAEAIVIESSTLDRAKLYSIQIRAAMLHLKMIYASVEDLKRSRAQYEQSLQAIALETLPVLPPDPLISVGSGCFGYNAIYQGYNDLAVRARLADIYRRSLPKLSFVANHVTQWRNYQHVFLDRDSNHSKGTNIVYHRRRIRVGFHSAFMRHHSVGLLMSRVIERLDRDRFEVFVITYTNSVTDELTRRVLSTIEPGHHVSIPHRNFEDAQLLIAALQLDVIIFTEIGMDPATYFLAFSKLALRSSSFWGHGTTSGIDTIDYFVSSTLFRHSTNKEDRSQTRYSECLFEMESLSTSFPRPPPPGIDSLTRKSLGLPSTSVLPLMILVPQTLYKLHPDFDSIVQRTLTAVPTSFLVFPIGNKPTLVSQLTKRWRHRLSDDVYRRIFFVRPLRSREFLALCAMSDLVLDPFPVGGGRSSFEIFSVGTPILGLRSRTTILQLTLGMYRVMEMEGCCMFDDEDSLVDRGVGLLRNSTARQALRREIMAKSSRLYDNDAVVTEWGRFFAEILANPPPKSRTSAEFSTGQTRLLDECSVRGAHPSHQVLYEVEVRSPLRVAKGRRQVKTLVLRGGDEPFMTAQQFANSFDPPLDELQTAFLGKTLWNMHHRRQSPVVKSFKMSEPGVSHVLIEIREGDDVYQVIPWLVKSQLGPSYHEAAERLIQRATETATSHMPHIQTDEWIQARSFEPALSPQRADSPQRDCIALVITTCKRLAMFRRAIESLARVLGIQRDSDWSRWFCQMLVVDDNSSAQARIAMQSLLPTFMFTFKMKEERGHAKSLNMALQRLQARFLFYVEDDWEFRGSNADFLRNTVTILRKTELVQVLINTQSSGWSRYLRDETSDTNIQYFRHEFAVLDPGHRFSYWPGFSLNPGVWDIAKLQHVLESQAFDEASDIFERVFSLRVWRAGLQTGYLAEQHCVHIGAEPGTNASAYVLNGLPRRFDIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ61</accession>
    <name>A0A8K1CJ61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable pectate lyase F</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_011460</name>
        <name evidence="14" type="ORF">Poli38472_011461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ61"/>
    <dbReference type="OrthoDB" id="94626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035706672" description="Probable pectate lyase F" evidence="12">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="27799" checksum="6492D72A72426F37" modified="2022-08-03" version="1">MVNTVTILCAAALAGPAIVNAASLPTGVWPASKGTVTYAAPKVIKTGEVFDGGMKTYERSNVKCAGGEGGKESAVFLVEPGATLKNVIIGKNQVEGVHCEKHDCTIENVWWTDVCEDALSIKGGSASSVSKVIGGGARYADDKVIQQNGPGKVSVDGFYAYDFGKLYRSCGNCKTQYKRQVEFKNVLAVKPKVSIATINTNLGDTATFTNVRVQSTKSNPKVCAWSQGVTSGEPKELGSGPSDKCKYSTSTVTITKISRLLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJS9</accession>
    <name>A0A8K1CJS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002463</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJS9"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24796">
        <property type="entry name" value="WDR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="97"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39748" checksum="6189B2F0C7506985" modified="2022-08-03" version="1">MADLDDHTPEEIHCDAQVFDIDFHPSQDVVALGDINGVVQIYKYSEQANTKVLELKHHQDTCRALVFAPDGQTLYTASTDKSIRAFDAHGNASWAELRAHDAPVNRLHVLSNDIIASGDDQGCIKIWDTRQHRCVVEWKEHTDYISGFATNPAVDHLIATGGDGRLSAYDLRKNVLAGKSDELDDELLSVSVIKNGRKIVCGSQDGVLVIFSWGTWGDMSDRFPGHPESVDAILKVDEDTVLTGSSDGIVRVVQVHPNKLLGLIGDHEDFPVENLKLSHDQKIIGSVSHTNKVHFWDVSYLFNDDGEDDGEADEDGTAENDAEMEDADSDDDDDSDMEANNGFQGRQAMPSAREQFFSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKR5</accession>
    <name>A0A8K1CKR5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKR5"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000026">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="7">
        <location>
            <begin position="69"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="19545" checksum="734309005ABB1A25" modified="2022-08-03" version="1">MLIGWWTAAEAVGSGRRTELLEPSVDIRREQAAMSDVEDNKKSGASYEERIKHVSVIAKPLASKKHTKRVYKVVKKATKVKGIKRGVKEVVKGIRKGDKGLCIIAGDISPIDVISHIPVLCEENDIPYIFTPSKVDLGASALSKRPTSCILITPGKSGFNVGDAYEELLADVKEVQPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKX8</accession>
    <name>A0A8K1CKX8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKX8"/>
    <dbReference type="OrthoDB" id="125370at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="256" mass="28599" checksum="B22AC412466A5F67" modified="2022-08-03" version="1">MPSQIQDFSRLHSMKIYNSTIFEWNAAAALTNTHHPVFSGFVAVRVNMSNAQLPPGLMSSDFPQSLGSIEFIETNLASLPENLDSSWPVGMVLGFESCQFSQLPPVLLRVAPSQLSFAGNLFTTFPFEAFAIPGLIYLNFDSNPIATLRPEPYRNVGIGSVRDLYPMDTTISSLPRWIDRLFQLVDEYEPLQFHNTPFCDDVLEIQHGGQSGFPATETPETELSVVMKDMVMLGSSVSCVYYEVDYPLALEDTWHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL31</accession>
    <name>A0A8K1CL31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cysteine desulfurase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL31"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24138">
        <property type="entry name" value="TtcA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="87"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="3">
        <location>
            <begin position="783"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1054" mass="116661" checksum="9FB4960160D3F714" modified="2022-08-03" version="1">MAADDEARVDATMTPVVSVVQAAKEEDSSARFFCEELEEDLVATIESSNEHEREVTHTAQMVQYVAENVIGRNQFFDAPFGDKALCYADFTASGKSLQCIEDYIQREVMPLYGNTHTTTSITGLQTTCFRHEARQIIAQAVNAKITGRGAEDSVLFTGQGSTSAVNKMITALGLHIPLASTDPSQRPVVFVGPFEHHSNLLPWRESVAEVVVIPENESGQVDAEVLVQRLQQYSARPLKIGAFSAASNLTGVLTDVDTITATLHMHGALAFWDYATCAPYVPIDMNPVVAGDLRPFVYKDAVFISGHKFIGGPGSPGVLIVKKRLLGNAVPTTPGGGTVFFVTERDHRYLSNREEREEGGTPDILGSIRLGLAFEIKQRIGAQQILARERAHVQRVRGAFGTHDKVVLLGRDDVDQLPVFSFLIRCGDRFLHYNFVCALLNDLFGIQTRGGCQCAGPYATRLLGLSKNDTIAFENALIEKKEMLRPGFSRVSFPYFMEDEEVDYIIEAIKFVAENGWKFLPQYKFNHKSGAWKHTSRFTRFPNRKWLSHFSMNLTKDVAPEKTTGFVADIQAHRRENLEAAQRLASESAKNAAPVAASVAQMLDDTYEALRWFIYPAEAADALKRGTAPVLTASIVGPYQPQRYLDGSLKHQWDEVAETTQPTPGAPQPASFAPAVCQLPMCCPVPSAKASSATSGRELGGKYPLRSTTGPIAQPVCAINGAPSAAIVPADASANLSHAQEISSKMAKKTAETKLFPTAPKKLMRWVGQALMQWNMIEEGDRILLGVSGGKDSLSLLHILLNVQKRAPVKFYLACATVDPQTPSFDPSPLKEYMQSLGVEYHYLSENIIERAACEMQGDSICSYCSRMKRGLLYTCCRKNKFNKLVLAQHLDDLAESFFMSAIHNGQLRTMKAKYWNDEKDVEILRPLAYVREHELKSFAYDARLPVINENCPACFEEPKERHRVKKMLAQEESLNPDMYNSIRRALLPLMDNSIYEPLNSIRACIEKKKHTRPKAPSNKTSKRMKTTETGPEVVETSGGKEVSVAELSDLVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLK4</accession>
    <name>A0A8K1CLK4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_009047</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLK4"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035432109" description="Multiple inositol polyphosphate phosphatase 1" evidence="17">
        <location>
            <begin position="21"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="59"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="412"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW64880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="51241" checksum="3A8C49B716F8BAD1" modified="2022-08-03" version="1">MLVLCWTLLMAVAVATPSTSEVLTQHMSTKTMYPVPSLAELKEETEAEKQAAQENDALCRPVQLNYVIRHGTRFPTIKDIRRINATHERLTHASAPLAWTQHWTNPYDPDRAGWLADVGVSELIAMGKRLRLRFGDAFHQHFNSDKFVFEHTYKPRTKQSAMAFAYGFFQEQLQSVLYHTDPIGQDTALRFFDNCPALDLAVARNKSATIEHKRYRLSKQMHRNLRRFQRLAGQPLEQSDLEAAYAACAFDVSVRGRLDEWCTLFDQELLFSMDYFHDLKHFYKKSHGNALAFEVASPLLQAVHRTMLQRIRGENTVEGHFRFAHAETILPLASLLNLTYFDRHANDREGHFLADTPLDIATTRSFRGSKLSPFAANIGFVLYECHDTTGPVPPTYRVQTLFHERTVTFPECDHARLCPFERFERMFWQWIHEYDFFSVCGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLX2</accession>
    <name>A0A8K1CLX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLX2"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="790" mass="92063" checksum="26ECB3744166206D" modified="2022-08-03" version="1">MATKTGRLIVHAKTGEMVEEMKEDLILVALYDPSCEKQEDHTFQRILRSDFKLRRINELFDCNASLLKDPFGNVLWPKDWVAQVLPPSGKDKWFYIIHERLEPPPQDDLNDPMYAGSTVLFLASVPKQCEALDLRQWLLFGISQDYEPLAKLREEIQLTERKRQMLKQKMNALPSIDVDGNPEQQAELRKKLSNAISSHTSRYDQDIAALSRKKARIEKFLMTEPLLLTALPIDKPTSAAGNNENETLDEFEKRMETRSWTVQFQGPRGEELVSVALEKSDWTYICLAQTRPTPKAFVEADHVEHHLISDKDLQKEINMRSIRLRRLRHGQGELLQVAKSSLLQEEDDDEEPLKPWDEDFHISSIGAMYKGEWRMGEKHGRGQEYTNVGFYDGEFEHNFRHGRGKLVYGKGSTVTGTFERRTRRYEYASKYQDRSYAPSLLNGDAFREGIEHGDHMRIEFPDGAIYEGEMTDGKVTGFGKYTSSTGVVDEGYFHDGLLHGKNCSRRYPDGTLQRGSFVMGQLHGRGVLKDRNGDEYDGFFEEGVKSGRGVSYFDQHRCKHVGFWFESMMDGRGDCFFKEKSAQPSSSNVEEENQLDDEDWDFWYEGSFIHGETQARHRCVDLKQQHKRHLPFTTNNKSVEKMPFITSEMPQLLRQRERRRQKNNERRSTREKTYLQQQEYANLSLYYGLLDEFYEKWVQKQRERKEDEVLDAEELERVHEERAAAVEYAENRLKFRKEKYNLSPRKRDLPQFESYLERVTLTERVVLERAMAAETSAIVSEIEKAGKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLX6</accession>
    <name>A0A8K1CLX6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLX6"/>
    <dbReference type="OrthoDB" id="162608at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035253">
        <property type="term" value="C:ciliary rootlet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097542">
        <property type="term" value="C:ciliary tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033192">
        <property type="entry name" value="ODAD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="64754" checksum="EB1A138D5D6CBB6A" modified="2022-08-03" version="1">MLSPRRAGPKTKVTAPSVQPFLSSMGILVGEETHIVDKEVNEVSTLRREYDTVKNTNVKKENEIRKLEEEIETMTTTLHSRMGDTAQLKAQANGIENKSALYQSKLDEELADQGVYTHMIQRLTSEALTAKKATNEKEKQLAALMNELTSSTSALLAARQEKTTSEQTYKKLYEDWWEKKQESIRALDDMQQAVEQTRLKYEILEQREVSRKKHVQEAIGEMKMKESRRLRHESYAQMTHFSEIQEELSDTDIRLLAVEAEFKKIIEAAGTNDVDKIISKFVNRDETLRALKEEHAVADARMRKLREKHKQLNETLGSLRSSAINTRTIYQEMDQTSERLKDIEKDAAALSEKFNRTNVMMDAFRACMLKCLTKLSTVRGSLDYDDHHELSRVMETPTSDLLHMVEQKLNRVLDVINREKAERELHRSEASGGAGSESAHDKHSFVRAPAPSESEQHFILRMSSPNTSSTNVRVRPTSRINAGRAPAMSVALAESVKQSVVRRPHATTHHHHHASNAKEEDGDEEYAHAVEMLTDDDVVIDRAMRKKLVGLVVNRGKRGKKPTMPSQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMJ9</accession>
    <name>A0A8K1CMJ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MINDY deubiquitinase family. FAM188 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMJ9"/>
    <dbReference type="OrthoDB" id="10263628at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025257">
        <property type="entry name" value="MINDY-3/4_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039785">
        <property type="entry name" value="MINY3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473:SF8">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13898">
        <property type="entry name" value="MINDY-3_4_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01174">
        <property type="entry name" value="DUF4205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="121"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="4">
        <location>
            <begin position="124"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="72383" checksum="46CED6A3196D311D" modified="2022-08-03" version="1">MPRDDPENTVLEGDVVRQAELVVMEYLKSWKCTKTLDAVMSNPRSINLPQSAVASELYAEDLVKKKKAGSLSVLEHMVTTMKSTSEANEVKNGGSDGSSASSSKPARNLSHRRSSGADSGTEDEGNVKWSKEEVSLLKKAIKSTTHVEDKNDRWKQIASLVGNGKSKKHCYLKYKELKEDKGGKSSSRSSSRRSSVDETSDPLKPVVAESKAKEVTREATKSDEKKKQAKEESGFVRSSTSAGLSKPLTTQRSESHEELQMEDCEDFDAVHPSVPRIAAAKGVSADASKARLSSGMGRSEARPPSAEEIESLRDILFPDDRKGFSSHWDEQGLFYSSASKLGYGLIQHEGGPCGVLAVIQAYVLRFMLSTASRDWQHPAVRDQQQALVAAMSHILWQAARASKRTQCLLVLNDPKSSVASSKRKFMSGVVVHSSGSPTQTEAVLMEHIARLMEPKGYGLVLFVLSVLLTKGIDNIRSEMDTVEGALGGGGKLIGNHDYCTQEMVNLLLCGVACSNVFNGKQLLEGTSEDGPKAVVLKGISAQGIVGFLSLFEAYEYIAVGTHLKNPQFNIWVVCSESHYSVLFADPSRLTDRTLDETKDVDLYYYDGLANQDEEIRLSIETKALPKKVKPKADDLIPPLNLVIQTKWPLAKVDWNDVEPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN18</accession>
    <name>A0A8K1CN18_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Late embryogenesis abundant protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN18"/>
    <dbReference type="OrthoDB" id="79718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37356" checksum="88FF6F26B9086F4B" modified="2022-08-03" version="1">MERLTTLWRKTSSTLQDTMKTTMDNTSDKLKQDAALFREKAKDAAVAAKDTVGDSAKLAGETLKDKAQQVGSTVAEAVQTKAGELRRVAAEKWSSTSAEAKDKAADYTAEAKERAQELRQQTGDKAAEMTNQAKDKFADYSNEAKERAQELRQQTGNKAAEMSNQAKDKFAEYTSEGKERAQEMRQQTGNKAAEMTNQAKDKFAEYASEGKERAQELRHQSGDKFADYSSEAKERAQQMRQQAGDRASEMSNQAKEKMRFSMADGAEKLRNSSNSMLEKLDPRARARQTRNRWLFVGFSAVAIYGFASAAPGAMSSYALEKVKIQEEAKTKRREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN43</accession>
    <name>A0A8K1CN43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007975</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN43"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000009">
        <property type="entry name" value="Probable E3 ubiquitin-protein ligase HECTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="12">
        <location>
            <begin position="66"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="13">
        <location>
            <begin position="370"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW65333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="724" mass="83895" checksum="FE213FE5B6B55A2A" modified="2022-08-03" version="1">MTTIFGKELSPTVATLVYVFLVAAVLILVGSIWYYWSYSRKIERFLERDNQNNNMLRQDLVDSFVARGEEEWPCSICFHTNHPSKTECVMCGTPQLVGVRTPSIARASGINRLDLIRQNGSILTQQSRVRSFHVRRLKQMNLTSRQKAAMRRHLWRRKKGPDGKLQWVRIDDANGEYGELRTPRSDTRGSEDSMTDSMRATNAHIALALRDFGEEDQAEQMERQTMSRRQSRYQGPFFQPLRATALKKLEEAEERQSTWHHAQENPYHQITMLEQIEEDRRDDNESNISTGYVRHTTADGNIEWAPAHGVEIQDSPHRIDCEDDLEEIAALTFAEKNRWFLQQVQRRWRNYDEGHIQFVIRRDHLVSDSMEQMLKCPASRFWERLRIYFENEPGLDAGGLIREWYECLSDALFNDDFGLFIATKGENMGYWINPASASKVKDHLQYYEFVGRLLGKALIEGHNMKMSLALPLIKHILSVPISFSDLEFLDEELYKNALWMKQNDNAELLAIDFTVQLITSEGKSETVELVPNGSNIDVTDANKAEYLDLLLKHYMFKSISEQLNALLKGFYDVVPMYLVTVFDYQEFDLLLSGIPDVSVSDWRTYSEVRWIKLEKPSPQEQKVLDWFWEVLASFTAEQKARLLQFATGTSRVPVLGFKALTSSDGRVRRFTVQFVARGPPPTGLMPKGHTCFNRIDLPLYNSLEELEKYLTLVINMEISGFWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN58</accession>
    <name>A0A8K1CN58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000023">
        <property type="protein sequence ID" value="TMW66564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN58"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="20792" checksum="1987174A1E66A70E" modified="2022-08-03" version="1">MTLTREAMLQILLISQLASNHTPTNQLRHPYHLPSYKMKYTALLCAAVATLAAAVSAEPTIDNPSNNKDIISPTEALDAIKEANLPAGMKLTGTLDSIQPPANTNASKEKTSTDIDTHIEDSGSVESKQEWLGYGGRGWEAGAAGWLGGFGPYRFGWSCGGLGGWAYPLGYWNTFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNC6</accession>
    <name>A0A8K1CNC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNC6"/>
    <dbReference type="OrthoDB" id="166806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="61120" checksum="D1A6F29942B89722" modified="2022-08-03" version="1">MDAPQPRFPAGNAFFNYQLFGGLRPGGSVSFLTRDNWGYAVSAFLSGYVYAAVTYILLRIPDDELGLNDSTSLKNVLALQWTAVLFVGIISDSWAPGGLRRKPYMLLGWILSSMLWLALFLLFWFVKDRPDEATFTLIIVAFLSLIVATNALDIRVIEFSQQEDLNQRGRLLGSYEILRISGQVAMHVLILIFGEPDSKSLLIHLPFPVEYMFLHLAIVCALPLYGLLQNAEEEKGNGSEPFKMNPFDGFYSSRDQLSALRPMSPIFSGRSASPTTVLAPRTSTRFKATYRSFWQSAKQKVIWQLMAFYCLLFFFSLFEFPGVRQAIQVWASETAASRVRRNCFSDIAFVLMIAIWRRYVVNSNWRILTGTVLIFTSFVFAATSSLVVFDVVRDPWITTVAYVLRAPLRVLTLIAAFVPAIEVAHYGAEGTTFALLGTFQNLVKLLAAECVSQIEQHISALQFPHDVVVKSEPSTQMRAIFGVLGMSIAFMIPVLGLLLLPRQKLDAQQLRVYGGYSSLPRAILAFGFLLSFPGVMYLQISRLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPU1</accession>
    <name>A0A8K1CPU1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPU1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="33683" checksum="BD489293B630CC4B" modified="2022-08-03" version="1">MATIISTPLFPEPEAYYARYSLTPEELEGLIRVRTVETDSNSQVVWSDILVAVFCPCVSIAQIASSTGSSYFVSLLVFASIYLSGLGFLIQSVMEYMECDLNAEVVLYAVGLEIAAFVVGPYVSLSTVGSQITPSIGCSYFVTVIVFALIYLTGLGFLLKSVMEYTVYDLNEEVVFYAIGLEFAAYLVGPYISFPTVGCVWFWHSLAEGLDDTDRIRIIAPAVYYYACVDGWLDVAFVLAAAYIRDNLRDRVNAPERRCCQHCLTTCCIWATLAKGVSSAKSYAIDYGSWDVGPLDVIPAYEGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPY9</accession>
    <name>A0A8K1CPY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000015">
        <property type="protein sequence ID" value="TMW66575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPY9"/>
    <dbReference type="OrthoDB" id="189102at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="80"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="644" mass="71547" checksum="F2ADAC1AC8FA149C" modified="2022-08-03" version="1">MGAESSTDLPMSAIDFETYQGLRYTQEVPNSREPSRGPIYVTKPLYVDESKLTLYTNFLTGVAIDNGTRNLYGTRKIVNGQAREYEWITYNQALAYVEAIASGLTKFARLKRGDMVGIFSKNRAEWCLSSHACDRMTYTLVPLYDTLGADAVPYIVNHTELTTIIYASELFNVVLECVDACPTLKYIVQYEDVTEAQRRMAAEKGLELKSLAELEALGKSHPLPADPPTPEDIATICYTSGTTGNPKGVVLKHRNMAIIGSMLQELGKFHSDTVHMSYLPLPHVFERAIMSLIVYLGAAAGFYQGDVLTLMDDMVALQPTLFISVPRLYNRVYDKITQGVAVAGGLKKMMFDQAYAAKKAARAEGYKLMRFGTLWCSRSAEVKEFMAVAFGCDFLEGYGLSETGAVVSAPLRHTPLGAHVGMPLPNLLVRLEDVPEMGYTSNDKPRPRGEIICKGPNVFSGYYKEPEKTAEAIDQDGWFHTGDIGCWNADGTLSIIDRKKNIFKLSQGEYIAAEKIENIYAKSKYVAQIFVYGDSYQSMLVAVAVPDPEVAEAWGTSKGLSREDSTAAKLVNDSEFQREVLNDMTRVGKDAQLRGFEFVKKVHFHPDAFSVDAGLITPTFKLKRPQLKTYFQKEIDAMYAAVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR28</accession>
    <name>A0A8K1CR28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">THH1/TOM1/TOM3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012237</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="159395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016316">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039034">
        <property type="entry name" value="INPP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009457">
        <property type="entry name" value="THH1/TOM1/TOM3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187">
        <property type="entry name" value="AGAP000124-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187:SF11">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06454">
        <property type="entry name" value="THH1_TOM1-3_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="THH1/TOM1/TOM3" evidence="6">
        <location>
            <begin position="92"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="822"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="921"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="736"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="839"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1380" mass="153534" checksum="A9207A99A4DC0DFF" modified="2022-08-03" version="1">MGVDAPFAASLRAQDAAMSLLYGPAVSAKPSDRDDGLVFLPQPSPFVGGVCVLLYLVLGLVALVRTLQMPKAPHRRRPDQLKRHQAFQRLLVVFAFVRSLSFLTLGLTRDVLNRLALCLFFSLVLLEVLFWIDIANPKRSTRSRRIWNAFLVANGLFYVVVIGLSALHLRSPPTVATDTDDQTPFEVFIARARDWDLIPVLLIALGSLASSLGLLYSTCKTRRRVGRVLQEAAIERLPARFNQRVETKLQRALSVTNVIMGICSALFLLRTIFYVQRPFSHRECGAIEDADTCILVGYGLTELVPCVLFLVLMWEVEPHLDLPSRRRSSLNVFAVARATETTPLLRERQRPPVLNTTLQESTSSSVYSRSLRSQRPSPLSSAVGGRGGSVIEEARRRLKRVLEESFGLRSEEESSRSYAYSDSLALEQSRVSSSHSHNELSSTFMWMSFQCFNLTLPSTSAVAVFLVLHRVSPDSKSPDGVESTEIGRTEVAYSKDPCFHILVPVEVEASGTLRATAYAVLNPSAMDDLDTQWLIGDALLPLSAYVSTNEHGEYGAVIPGTASVHEFFSPLSRTHSPGQLVARCEADIWKESSVLDRELYQHVTRAFVYVPSATTDSSNTPPRTKLLVEEELVESVYTWEIPYQLLQLIHADLLVQLDALKREIVDDNTSSTAPEPNRPVETVAYSYSDAKLKRSESLKAQEVSTRSRSAPSIGMLSEMILHIQDDALKRKNQRWRRELTHKMEEYIQEVETAILRYERAAQDGLTFKPSTMKANAGLSFVAVNLHQQLLTVGRGVPSDPRDIRQDEKTQDGQHYMRLMNTSFVETPVLPPHTTGSESPETEDEEGDDVVVPAPAPGPYEALRRRVISFDSAEQIVQLMNASDTNSGGLTLSREQCQLAESIVALGIDGIAFDSDVRAEIEAEEEPPVPGDRANSTTTATHDQAKPSNDESAQPSSVRSTPYCERSMYATTTVGAFAAHTYKFRKGGTRQMRAKLERIRRRLSKEAERPGSDLTVEGLEREYLELKWHIDRRLEVAFCQAMSALVTCFQQTLYVHLYEQQATEAMQVSQGLTYLEQLADVGFLFSVESLLSTYSKEAGMLGDMEAAVHELERVRIKFRPVATPRAAQFRVSVTSGQDGLVMELPLITCSPMSHRARSMHRVPGQDATTGAVYLNLTSEEQWTRLRRVLNGTISVVPVIFSQGMNEMQTVANTVGKDLLQKEINAENLVVLEKYTQSFLEWQQTRGERHLALLDVVGTELRQLREAIERAGRGKHMTILTLSSSIARLVGGGRVTCCKSAKDRTSMSLTLEEATLLVRTHGLRASDRDAFTTLLRTHGVRRENARKNIGRAQYCFNAFQNFLLPTDYQCPPGTGGGGSGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRR7</accession>
    <name>A0A8K1CRR7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRR7"/>
    <dbReference type="OrthoDB" id="167011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469011" evidence="2">
        <location>
            <begin position="18"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="28802" checksum="DEA8ED4056B066EB" modified="2022-08-03" version="1">MKTCVFLAATLFAAVSAADINIRGAQRAEAPAAADVRVRTADILNRPTALINKNTVAMDNNVFIARSNLLFSQNDRLAMAKQVEQALNAEEQAGTAVTLTRSVMRSVSAPDTDSSLMTKASAVVAAKGGDASTLSQRIADFVNAVADKKEQSIQSETPRGMQLSVGTKDILRQPTAVINKNVGMSDNQITMSRMTFAPSRNDRVTMSNNAKVANAVVPGSAIRVDQITAREGQDQDDASSEEMRVPDDKKEQFGWGWGFPGYGWGGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS94</accession>
    <name>A0A8K1CS94_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS94"/>
    <dbReference type="OrthoDB" id="161958at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="17785" checksum="C4460B73D13265CE" modified="2022-08-03" version="1">MKLFIVDNEHYKLTIVIVLLNVLIITECVVLLVRATNPFFTSSDHPTSAFALFLAVQITAAAVLSVGICAAKDKMVLLNRGLFKTVAFTNAVYAIIFFVRKDVLAGFVMSFLVLINALGSLVCRRFFLHLTWNQQLPTTAPSSNQQLPTTVPSLNLNNTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVG3</accession>
    <name>A0A8K1CVG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitosanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVG3"/>
    <dbReference type="OrthoDB" id="76114at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.141.10">
        <property type="entry name" value="Chitosanase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.386.10">
        <property type="entry name" value="Chitosanase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000400">
        <property type="entry name" value="Glyco_hydro_46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023099">
        <property type="entry name" value="Glyco_hydro_46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01374">
        <property type="entry name" value="Glyco_hydro_46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035449995" description="Chitosanase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="37142" checksum="BE98DE9827A9B3E7" modified="2022-08-03" version="1">MWRTWMTTLLLAVAGASAELRVNRFPFDAISGNVTLEQLDTIMSLVSIAENNKAEWWENYDYCEDRENGRGYTVSLVGFCSGTSDLLQIVRYVEKADPDHPLAQFVDALKTVDGTDSTKGLTSLCASVRSSNDKTWQSAVWKGIKREYWEPATRWAYEHGLTSALAKGFLLDVALNHGAEGLDLIAGPLSSVDAMEIGEATYLEDYMNSRANLIAAKGEPASERVAMWQTILTEGNLELERPVADIKFKGDMFTIGGDDENLNGDYEAGKVSTSDENRSGLDTTSETVPKEPVGNALVIKSKNTEAVAESDSDSRLSSASVSSVASTLVVALSVVCSWLHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9L6</accession>
    <name>A0A8K1F9L6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013241</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9L6"/>
    <dbReference type="OrthoDB" id="4866634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF33">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF3638" evidence="7">
        <location>
            <begin position="42"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="8">
        <location>
            <begin position="299"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="50325" checksum="E87A70737592C365" modified="2022-08-03" version="1">MANLTFMQLCVLEDKLERVISRSQANSLPSLAYFVEELTCQRPWECRNCPYWLVFEVEGRLQIRPEQHYIAEELIYNPGKVCQLNMGRGKTRVILPMLFLYHSYETRGKIARAHFLSPLLSETRQFMHRVLSAGVLRLPFIEQPFERQTELSLMDVLRMQEAVDDVKQFGGFQIIASEHRLSLELRRLELSLKDSSDDATNQEIIAALDKLLDDEQYINIFDESDAVLHHKYHLVYDIGDATELDGGTERWIVAEALLRVLVGTESPDFGTAWFAAFGVLEHCLEKRSRVNYGLPTPGTRPKSMAIPFTAADLRADRSEFCHPDVGIVLTLLSYYHVGLRDDEIRLAFEKLLRLDESEQTQYYREWYASVRAQISSDERTQLEKVEDVALDNPSQFTLLCKVYKYSMVVINFYLNQCVFPRDTKQYPRRLARIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB47</accession>
    <name>A0A8K1FB47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phospholipase D</fullName>
            <ecNumber evidence="2">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB47"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09105">
        <property type="entry name" value="PLDc_vPLD1_2_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433437" description="phospholipase D" evidence="7">
        <location>
            <begin position="23"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="68038" checksum="CED294352C084FFF" modified="2022-08-03" version="1">MRCLSRLLLTAWLATSATHVLGRRVPARRLDDAAPSNASASTNTTRFGVTCEKRGNVFNVISSGCMCAPCHLCELHYSDMTCHLIVDDDTDLSDGSDIKPKQPILEAEKWFLTESEMTASRGGVPRKDLAVFTKKNQVTTYAVASEYFEDVYDDMENTEEGDRMFFTGWTFEEVPLIPTVERSELNDTNLTAVVARALNRSVDVHILGWANFFETDINVASQKVFNALPAPKYGEALFLFDDRLPDATASNHQKTVVIKSNDGLVAYVGGLDLAANRWDVLAHDKAELRRQSGVERADTDGWMDVQLKIDGPAAKDVAANFLSRWNAKKKPLDDTFDPLFAFTNPNYTTLPGLDVDSPVVINEDGEHAVQIVRTFSCKYDHYEDIAPKGEVSIFHSRLKAILQAQNYIYIEDQYFINVPELLMALIEVLPRLQRLIIVTQPPTADVVPLGYEKYQFDAIAPLQRQFPNKVQVLRTKESRKIYVHSKLVIIDDVYLSIGSSNWNRRSMTADTEITANVVDSKKVKAPEGIQVNHVARDYRIRKFMELSGESYKTLDKLTLVEASNLLDKRAKEADSILDVFQVDKEVKYLIFGPVQHFADPQYQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD71</accession>
    <name>A0A8K1FD71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">THO complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD71"/>
    <dbReference type="OrthoDB" id="20582at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="336"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="130"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="78826" checksum="071241CDC1183051" modified="2022-08-03" version="1">MGGSGDARVARLQELKAATEALRGILADVDKQKHAGAVDKARLKQQRWQAVTLICAMKAGLRETFLASDAWKTRVQEQKDVVEAHQLKLQNLLYEKDHLAREIRRCRGFGTKEMDKIEFENGRLPIAVDAESHRQHLDQLTRELETRKRMKTQLKELKAKIDEVEAASQKKQTFLDGLRGELDTIEDSTRGLQKYMHKPVTATLKSQQDASTLLPAPLYTLYCELEAYQTASGCAKQMALSIVGSKGLKASALRVKKREFPSALTSGGRVKNELDAKEPEKKRLKGPSRSPSIAKLEAEKARETNALRAPSRSPSQGHSRPAESGEIVDVVMAENGTDATANNGSRADDKDASEVKRIDDDQDELDDANDADNERDLWRCHEKALLLKLSLAVDDEVSGSTTTEFSLLFQYFVNARVVSVDLLEPSNAPKNVLMNLFPGDDGLSMPRLATAYEFKGVTPEELSFPTNLVASRPYHWAQWICGLFPLKRGDGAADTRRPEPSIRNTMTQLVKRLVVSVQLQQHLQALAKNSLAPVHTAFTGHFPARIKTKLNGWKEIASPNVDLLRRFTSEKSEQLTLSTTGCRYYRVTFRHEHVQVEGIVEISPEYPVRAPRFRLSATDSASTSIENHLKEIEIEVNTFYDELVSKDCTQYLLAHQLRKVQQCVDVLGSPEGQLPRCFGRERRGKDRRPAFVVDATTKEARHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDH6</accession>
    <name>A0A8K1FDH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar protein sorting-associated protein 8 central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002849</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="4">
        <location>
            <begin position="764"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="5">
        <location>
            <begin position="1455"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="858"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="898"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1487"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1661"/>
            <end position="1696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1764"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="862"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="900"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1494"/>
            <end position="1506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1794" mass="197425" checksum="4EA0BD3F4C7EEDD2" modified="2022-08-03" version="1">MSIRTPVESLLLQDSDDEDLGDVDLASITLEEILREEEAAEDGPASPTGEDEFFSPATMTMALTPMPGMEVVNAPVKARSGSLHIDRKKSVTEIGVGGHAGLLSAASSDKLNGAMRSPLEIAEARERQLLSCVGVELVSPLQVKRRLRSNARTKSATKRKPANRPKSKKKITLASLNADANGKDEKKSTGVVKVEAMETISRQLKKNIEFKEHGPGSPTVVAIHSKFIAIGTSKGLVLIFDHFQNIRQVLGNTNDSDSDGAITAIDVSPGSDYLVCGYQSGRIVLWDMIKGTSLKAVSDAHENPVVSLRFLKDQKPVLMSVDTNGIVNKVNFSKMMGMVYVVDVDPIYDGSAGRILSLSILPQSAGNAKISHLTDQYCLAALSSEKVTFIIAIEPEVKILHRWMRPEEIGADDPVLPSLAFAWISFPGSSRALAPVLARGWGKHVQFLEVVFPGGQNHSHSKHGWPTFEEHDQIESSSDTMAIQWLGDQVVVYLNSHDEICVYDVMSRQELEIVDVSSLELVFASYRGKNARSFSNSFRGCDNILYLLGLKELQTARVQPWTQRIDTLVEEGQWLEALALALDHYEGLKVAAADRAVRDRFPPVFFRDRQNDQCLVDLLHMCQTNQRTGEKEDVFRHEDGDEVRWRCGEDPYPIEISKKLEETYQKARSGQVTKNFVPISVAERVADLLMEYVRLAIANAPSSTATTTSSGPSWAKNNLKLDLAKSHYQMLAGVCIEFCAIINRTDLLFGEIFKRFKDAGKTDIFVELLEPYILADRLRSLSPEVMQAFVTHYSVTDKLPQVEQCLLHLNVTELDIDTMVKLCKEHELYSALVYIYNEGLHDYVAPIDILLEAATTEKNKPSSRTSSAASSAEPSPAKPPPAVGGSKVSNLAAAFGGSTRGITTPARTLSTTRKPSASSSSENVLTGARRRRLYGYKLLLYISYSLSGRSFPKHELLAPQLVNKVRAEILHHLFEKNVEGNKTLSPRLMALVELDAKEFFNVLARVFDDPTVEFEGEKKEASSRMTSRYETARQAGLAKCPSRLSMVLALAEVVVGPAGDISSSPFSSVEHGHFFMFEARLLSGGSIDAQDYADARGAALGKGGSVGAMMNSLMNFLALGPASLSGRDNAAATAAAQEEGFDKNGREAMLVRLLQKLRKDYYDHDALLQSVKTEGMHRAAVILYKEKGDISQAIASYLADAEHDTRMNVFNYIRVETDKLVDEDGDNSADTAARRKVIEDAVLTHAGPLMETDDHSFVVLIIGQFPNLNNKVIQKFLSMGKSGAKLEFVYLKQMLKGSSNKTDVADEGDVVKELLDRSKLRLADDPAVQERFVRLLCEFEPEGVFPYLESHDSYKVDACLKLCKDFSITDAEAYLLERTGDVTGALTLILQSLEQKLKILKPALRGYNMTSTTDGLVGGASALSRTQVADSIIDSLSEGREAKQTLEVALVMCQRNSLRNRDEQSQKLWFTLLDKLLRIQNAVKRAQAAKPAPSSSSSTTRITTRSGGSGAQTAFQVALNELIRIILERMASSVSLKSILFKITNEHGRGQFGDFRPTIFGMLDTYNYEQNIYQTANGLISADLYEQVTTLKRALARAYAPPSDTCGYCKVSLAKPPFGMAHSGASGGEKWNVSTSMVMVVSRQAFHESCAKAWQQDVDASATTTRSRPALQRQANAMGLDRVPDRGGSVSTASEVGLDDDASLKLQRNKPSTRRYLNRLKNARKSTRRPVSLHVVLESLIREDNGRNKYLKSSRAVYSLRPDPEQANKVKKRIGTRTPGSLPVNPIQRGSIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF58</accession>
    <name>A0A8K1FF58_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF58"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003838">
        <property type="term" value="F:sterol 24-C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34097" checksum="5FCD6E51EAFAF427" modified="2022-08-03" version="1">MTKAVEIKTMKLYHHLERIERRLKHAAASKDVELVPEKTSGDDSIDPEVLGTLDSLHFYGDEPIQAVQKLLGQVRETRGVSDAAAQRVLDIGTGFGGTARLLAHRTGVQVDALELQPDLSDTGRELTRRCGLERQVTHLTGDFLVRPVTHERYDVIVGLLCFLHIGQWRELFTRCCQSLQPGGVLYVEDFFRRNDEADFNDEEKRILREDVYCVELCVQAELQALIQECGLEVVQFEDVTTKWLPYVTKRAENYEANLEKHIMLDGEATAKGLNHFYKSVADIFTRGNLGGYTLVARRPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF77</accession>
    <name>A0A8K1FF77_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006528</name>
        <name evidence="4" type="ORF">Poli38472_006534</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF77"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272204" evidence="2">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="135" mass="15657" checksum="54FF8B50DE6F8428" modified="2022-08-03" version="1">MLRSLFTTLAVTVLALTVSAQDIQKDDEQVSLTINTPEPQAVDVRVDPALPSSVTLTGERDRLMQPASEEEPKDDNEAEQFRRGGYGFRHRFYHPYHRRGYYGWRYPMPYWNTYGRRYYGGGCGYGRAYGGYYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFP5</accession>
    <name>A0A8K1FFP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFP5"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049818">
        <property type="entry name" value="Expansin_EXLX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041144">
        <property type="entry name" value="expansin_EXLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443567" description="Expansin-like EG45 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="4">
        <location>
            <begin position="37"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="273"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="39371" checksum="5F804F1ED88274C9" modified="2022-08-03" version="1">MMRPAIFASLASLAIFQVQAQSFQGDMTAYTLGQPSAGNCNFLTAPPAASQNYAALNAAQWGNTANCGRCAEVSCADDRCSDKTKTEIVYILDQCPECKQGDLDVSPSVFKSLTGSDPSRYTIKWRFVDCPVSGNIQYCLKSGSNPYWTAIQPANTAAGVKSLTIDGKTTSMVPSAYYYLLDDASTQRNYGSVRVTVTSLTGEVIEDTVSLSAGSCTEGNSQFSSGGSAPAPAPAPTPASTTTAPVPKTEEPTYAPTETPEVKTEAPEPAPAPVETYTPAPVATTSDPSTQAPTSAPAVTTSAPAATKTPALTTAPTAVPAASTPATVTPAVTTTPSPSANNTAGTDSDDEDEYDDDNDSDYATPVPTSTKKGKKKCDSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFS0</accession>
    <name>A0A8K1FFS0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFS0"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18506" checksum="0485372A76C6F7AB" modified="2022-08-03" version="1">MSDEKRDVDIWRESLVRYLGYSNELGESFRPIVPRLVVPSYVVAFGYVLGDTYDKATKASQVADKQELPSGKLTALVANATVDTLLWQTMASVVIPGFTINRVVALSSTIAQKTLQQSPVLRRWAPTAIGLGVIPLIIHPIDHFVDFLMDNTTRKWSSSFLSHDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFX1</accession>
    <name>A0A8K1FFX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA primase</fullName>
            <ecNumber evidence="10">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003163</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFX1"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000003">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 10" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="49513" checksum="A36F22E5915DED0F" modified="2022-08-03" version="1">MAHEEFSTDLLQLYYDRLFPYEQMTKWLAYDGGETYLFRRELSFTLENDTYIRYKAFHNADEMRSSMTKMLPFKIDIGAVFSVSPADKGKVNANDFTADERELVFDIDLTDYDDIRTCCEGASICPKCWRFMVAAVKVMDAALREDFGFQHIMWVYSGRRGIHCWVSDEFARGLTNDARTAVVQYLSLVEGNENAKRKVHLKEPLHPSLDRAYRILEPMFEELILSDEGQGVFCSEKQWIKLLDMIPDEDLRDQLLHRWSSLSCSSSPREKWMEVVDGVEKIVAMGLNNNKRQSLQSDQRKRNIYELRTCLQEIVFAYLYPRLDANVSKQRNHLLKSPFAVHPKTGRVCVPVDADNIEEFDPFTVPTLGQLQDELNKNDKAGGSDIDRTSMKEHVKFFEDTLLKPLEVAAKQKQRDAKESNAAMTGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG62</accession>
    <name>A0A8K1FG62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG62"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="561" mass="61239" checksum="DE4F2F026F876341" modified="2022-08-03" version="1">MNYGNGQNPPGIILYDEPARRLHNSSSIDEALTPLDSISSPAIYYNDPIYLQKGPRGASKSVVGTPNRFMYQPEEIPMEYPDDGSSGRFAFLRRTTVQIIIGVVLGIGIGVLLSRLQASSDVSDLVNLPGKIFLRALKCFVIPMVFCSLSTGVANIVLLRKVSAVGTRTALYFVLSSLAATSLSLGVSLLLRKLHSDLQFEPRPPEVAFMHFLCPDGKYINIVNDSRLDCGATAMNTTTAFELIDLSNIILDNSPVQTVTVTEQVTKILQSIFPVNIFQSFQDGVLMSVIMFSIAFGAAAMQALPQQTSPLLELLNQMNKIFFFVISKLVDWSPVAVCSLIAGSLSSQKSLSKAVNHVGMLVLSNLVSALIFELIFYPIVLWLATRRNPFPFMKQMAPCVYFAFGSASSLATLPITLRCVESTREVSRALSSFVVTIGSTVHMEGTAMLFPNAIIFLVATSKTEIEIGPVQCVLIILVSLLASLGVAPIPNAGLLMVYSVWSTIFPDEELPLSYSYLVAIYWYLDRVNTVCNVVGDAYMARVIAEQVDEAFENSNNQGDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG66</accession>
    <name>A0A8K1FG66_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG66"/>
    <dbReference type="OrthoDB" id="191135at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043379">
        <property type="entry name" value="ANKAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058678">
        <property type="entry name" value="ARM_PUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46464">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46464:SF2">
        <property type="entry name" value="ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25598">
        <property type="entry name" value="ARM_PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="173"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="3">
        <location>
            <begin position="187"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="339"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="626" mass="67289" checksum="810F42E8E0F8D6A4" modified="2022-08-03" version="1">MGVATPETTDLSALLQALNLGADADKTNALREIQALMTQEDGIEKLASAEVVVPLVKLLKTELAEQKEEAAHVLAFLSMDEFVHEELFDANLLETVIELLEGSSGKLAESFAGILAGLSPCEEFGARIVECKGLPAILKIVESGEGQARDDISLALGNLALYDEIKEELAERGVIKLCIGLLTSESETLSDRAAFTLRNLAEEDPESQKRIVEAGAVEPLITILKTGSFTVQKQHAAEALSWIAAEEEQATTLAPLVAETLVDIIKGENPDELKEAAAEFFLQLSGHNTTTSVLVNEASLAALLQLAQSEEVTLVDTALDIFQNITQDAAECAKFIAAGGLPILVKIIKESVLELQDQALAVVMNLTYAEAGQPFIDADGVSLLVEFLKNAEPGYRASATGVVWNLTMYYEGAIKSLVDAGAIEQLVEVIKTGEEEIQWEDVEGEEDDEEEEEEAAEAAADAEAEGEEEEDDEDDEAEEEDDANESQHAVNALIELSNNETHGADVRARIATSDLVDVLNEVLKAEETTSFRVSVLKLVAALSTEKDFVARLVEGEVASSLLALLKVDDEDEREETISAIAVLAENEQFRAKFVEVKGVEAVEALAKEGSDAQKEAAALALTRLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG71</accession>
    <name>A0A8K1FG71_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG71"/>
    <dbReference type="OrthoDB" id="90188at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="82477" checksum="406B98616F8C2A9C" modified="2022-08-03" version="1">MQDTDSSASVKRAWSSTLRPVVVEPDGTLSTTTTHSTSEVKLELTPALYRIVWISVVLVCFINAIFATTIAAVYYVGLAVRNGYMLEWMGLLPTSEIPIVLALYVLTTLYFWKMLFHLIFLSIRQQRLIFPTTRSRLEKAQATPQPSRWTPKFVHHVKESWLELFAPGSPLELTETKFEALYLLREVTEMITQTYQTYMSSTLISNEWVNIFYVGTLVVNCWLSPVIHVTTHSYPAFQRFLYLCSDVVLDCVSTVFVPMFIFISVIFVALMDGQEQTGGDTEYAFDVPYDDVFIMDVIKGVQQTLVLTWLDVFTKLLPFLSMAGCLKHIMRLVFRQENRTIPRVNSLVVIKRRENRVPIRSRRVHVANSDDISTTTLVPTVSRARGRRLIRWMVRLHWVFILFFIWGVVILAMHLQAQRVSRNAPASSKVGCKSSSRPWLASQFSCTILEINCCRHGMSGLAHEIDEVLQQVNPNGLSSLIISHCSSLHIPSRITDLPELTGLEITNATLVEWGLDAVVSEDTMPSLQMLALVGVNMSALPEAIVSPDFPRRLRDLTISASNLTMLPDDLARKWSSLFNLFIERTQVTLVAPALDVDGTMRLSLMGNQIHEIPDQLFAHSQFSVLSAAKNPVTKWPSTIGHLDELTMLLMDHTEIKELPSWLLEEGKRRGQSGNVITVSAGGSAYCQAKKTETSALIDESVTGLKIVCREKQEEEFEAYPLSYNIRHRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGZ4</accession>
    <name>A0A8K1FGZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_002271</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGZ4"/>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15565">
        <property type="entry name" value="PHD2_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15566">
        <property type="entry name" value="PHD3_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10531">
        <property type="entry name" value="SET_SETD2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055198">
        <property type="entry name" value="NSD_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22908">
        <property type="entry name" value="PHD_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="299"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="AWS" evidence="17">
        <location>
            <begin position="568"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="15">
        <location>
            <begin position="631"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="16">
        <location>
            <begin position="757"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="779"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="786"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW63330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="929" mass="103286" checksum="75926C1FD6F183C0" modified="2022-08-03" version="1">MTETTMEAASMQPPKAANASMPVESTTKNSGKVVATAESKKTENPSQESELNGASAVDVTMSEADLIALSADLGKKRSAPDSAGTGNADGGAAAAEEGVPRKKRAVESSGDVEMTATTEPDAEDTVADSQSSTEGVDLTEFHANLKEGDEVDVFCVRTKVWLPAKIEKEEADVFTVHFLNWNKKSNEEINPSSLKRIAPRGSEAADAWHKHEEKQEKLRRSREEKARKKVELLTSATTADSTEITVTEAPAFIEAGLTRSGRKITKRLVNEASVIRKKPSSKPVKKKSAAEYALEIQEENTCAICGEYEDDAMTDMIFCDGGCLNSYHFSCLGLDEMPQEDDKWLCEQCRTNEQQCFCCGRNDTIGERGGVFRCSVPSCGKFYHQNCVNANKLSRRMGRASKPTASTAESSAEGNTTTDADESSASEAEMGAFRCPRHICSVCEDTKRGSDLMYCLKCPESYHPHCVPPSARYNNVGLLCFRHPEDKLPRIPTQFLHDRNFDSVVVDYNLRLPTLFLPRQEPDASNANDCHHFRLSVDFLDDVKQQPPTYRKLARNLYTFKQPKESLEDVPLCVCKESCGDDCINRLSFTECFGPAPTPGMPFNRADKNKESNCPLGEQCGNRALHQRMYPKFERFHSPDKGWGLKILEPVKAGQLVIEYVGEVINEEEKNRRLSEHARLNPEDKNMYIMELSNGVYIDARHKGSVSRFINHSCDPNCHLLKWNVRGVNRIAITALTDIEAGVELSYDYQFHTSQAMQFRCFCKSKNCRGTMAPEKLNLSADEEDGGKKLTKKEQQKKLKRAMQQEKLNAEKEEKATARRLSCTAPISRSIARTGPATRELLWAKQTHPFLMRNAIRGFDFLARREMLDKRIATKAKQSGVVKTEVLGLESPDDVTAEALVKDTSSGVRLKVVKAVVVVQADSNAVKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI95</accession>
    <name>A0A8K1FI95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI95"/>
    <dbReference type="OrthoDB" id="73788at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="44650" checksum="F411386B7BFC8223" modified="2022-08-03" version="1">MSYDFYSLVSSIKDKSSQAMATLSSDLMEFSTIVQEDVAEVAKTVRKTVHEKSEAFRQLAEQQRQEIEKEEHGETEETSGLLHDEEEEKEEEKQENDEEEKDETPAASTVSTTASSLFSFASLSLEQVSSKLLHTADELLGALAGTGEGEEGAEDEDAVESARRYRLLALQEDPDTYTEPPMDVETFQKWRTSVSSDELASVQAEVLAHYPAVVEKLAELVPGTLSEEDFWAHYIYKASLLAAQEQRGADLLEHALNDSEEEVSWDADSPRAGAAEDATEKTFEAESTPAVPSIVDVSGADEARAMETASSDGESWIELDEQRRDAIQQPPLSSSSTSSFVPVVAQHDGVPASAPLQQHDEEDLTWGEDDEQIATATTTTEATESKPAAGVKTATASNRQGDDWGEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIC7</accession>
    <name>A0A8K1FIC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIC7"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="5">
        <location>
            <begin position="51"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="180"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="241" mass="27620" checksum="D50DEE867FFD08A7" modified="2022-08-03" version="1">MSKTEPHIDFDDAPTDDHGTRAHRSLRLHVGVFSKHKGVRYDADGRVRVCRFCEILRHRDETFLYEEDALVVFRPLHPIAPSHILIVPRAHIRNVKKLTVDHIDLLRRMRIVAEKVLQNHSELSSPSPPTSKDDTHSMETTADDDDVLPYSPMADQGVVGASSNDCRFAFHVPPFNSIDHVHMHAFRGSTGYFGRIKYRTESWWCRSFDEVMTRLEQQIVPEVTHASTAVIHARPVSTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIL3</accession>
    <name>A0A8K1FIL3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIL3"/>
    <dbReference type="OrthoDB" id="78113at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="614" mass="65892" checksum="A4C82724CD5E0DEB" modified="2022-08-03" version="1">MESNKTSGAASGAGSASATASASSTALRRSKRDATTRVVAVKSEENAAPAASQRRSQRSSKSTYATPSVATPATKDKRPSRSQRSSGSTIKEESVKSASVPPPISTSSETSAKHRRPSRRQSRQLDAAPTPTAASGGTRSAAQARRLFLGQYSARCATALCEVILQQMKTQACDPRVLESEVSPAEINWTDVATQMAKLHQVIMKPRECQLLWKFLAYGHEPVEGTDLLDGSDTEDYEITSHVLNERRRHQAIEIKQEETLVVSVEATNECEQTEDATSNSKRTNELETALAIDSQQTTEGENVEQPTPNSTEEVAQKPQLQEEVAPEGTSATQEENHPLVRLHPIYTQPSGVPDGWESLPPQPSLPLVYVAEKFLKRKPAVPVGAPTPVQPGATITASTSAHSTPSQTAPGLNAHQIAAAAGVMLSEEQPKPKAKRKRKSDAGADTSKKQPKPLISSSTPNAMKAPYVTSNTPPPNPTPPRNPVEFFYQIYKENPRVVVFDAQVPPPSSLSIEQLYALFQRAPPVVRSRCEQLALDDQERFNRECVRRRIWEKAMTSATNSPAVTPVPSPAPLSVPTATKPSAQPSATTTTSLGAPSSTQSAVKAPSQPAGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ43</accession>
    <name>A0A8K1FJ43_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ43"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207:SF2">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="25875" checksum="7E42D9E39000ED5E" modified="2022-08-03" version="1">MASRSRSQEADVLSLDTPESENDRPKTPRRPGTSSGRSKQLKVTEFRKFLENDELPLRIESAKSGGRRVVWTTSLDQLDFAQFLPLCVGGLQETLEPYPSFAFDAGMQILEHGLNDKRVLKCLPLIMNQIKSALGTREKEIVHRVLLLLQQLSVCEGVGEALTDYYRAVLPLCNILQDKHLGTGDELTREMVAETLETLEAYGKDDAHVVIQQYVPTFQQQFPSDRLVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ54</accession>
    <name>A0A8K1FJ54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012633</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ54"/>
    <dbReference type="OrthoDB" id="89663at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="16934" checksum="CCA5C4A7779044BF" modified="2022-08-03" version="1">MENDDAKLWRAVYDVGSVFSVEIDRNVDIEALRTATSNKVFDTDQHAVNAHALTLYKSQAKNGEWLRDDREVRNFLRRGVSAAYEEMRPSWTLEESFGEGFSLSRGDIHVLVKLPETDAIPDDVPHAKRRRVERNLPVKELWRYCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ74</accession>
    <name>A0A8K1FJ74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rap-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012693</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19311at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000001">
        <property type="entry name" value="Ral GTPase-activating protein subunit alpha-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF11">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="1789"/>
            <end position="2005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="979"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1375"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="995"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1015"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2035" mass="227146" checksum="04B26C589E2CEC85" modified="2022-08-03" version="1">MESRRGGDPKALRKDAEIKRLAKFYAVDRPPRKRLRTLLDFLKNPTGNAPSDGNLVGTVQQLLAGASKEAANGADNSAILNEFWGDMNNCSMVFDVLSDCVTELETLYVPHENAFRRRKKTLEAEDWNEVFEGLEVLIRNNVPNIHDGWKNHGFTLLFSKLLKRDNHALIKKYAFRCLALFTDATRNLQQLVSVGPLSGSPSRSTVSNLTDDAAMDDEDASSRGTSGSRRNTLHLELLRESVDFSPYGGGNILLPDKFINQGVHVEGWIRATPTQAEEPVDMLKFIMDLSLEREDPKITSTMKSSAKMRGDRFEYWTELIMRFYMPLLYPKICIKAKLKEEGDNMGFFHHCPGSFQRVVARWIYKLRSKSECMEILWSRREFAEVIMETVRQRFAYRDNELVLDAIKFYSAICTGGQYIPMGMQTQIHETSRSMISHVSQLFHPSVQLDDPKILVHCIELLEVIAQRPLDEYSSTYLRKFVISTIDNCTTLREPGNTAILSAMVSVVIHVWMHAAIVSKATGQQVWLELTIAIRRWLLNASDAKSLGPELINCWKREVRFASCLLMYVMDEGQSMLKVTPEGAVILPHSGSDGKDNASKDGGVKQGYIQSAANFLMGKVTDVSDATVLLDRVLHLIPPPTVSSLPPNLHLSLVEGMLQLNELWIDSAISSQRTMPTVLHGISPSTVLALFGEWFLPACELDSPDFQNSRCVAIVTLCKLCSVRCANSLTRMHLTSLARILFQGIMSPAGVVVSTVLQRAAPIFTLNLDGMNALVPAFLYVVDQIIVQNIWERAQQSKVKSSNWNRELSASLGIVFSILALPKRYPQENFVNWRQKIAQTSISEPQFEKFRAALEEIPEIDDNFYVIVGRVLVRIASLPFTDIVAIKKRALWGLYSLIVMHLSPATSTLVDRSHLSDWIVQILDFCYSLDFSVSMTALSILQDLSDFHSQVHDMEPVLVPRIIMTLAVFAQQQVEEASVEVQSAMEKQGNAAEGHSSITGDKTSMTGSSRGSRVPSLRDSEIEEEGKGKTKTPGKSNTPTPPQSTSPNGGQKKDQDIPALRLIVQKTAAIFECLRFWVMHRVEVLQDADVKKILFTAIEAALVGSLPDGEWQREVERARAQQRRMSLPMLFLGLQMRASLDNEASQSWLKWFEETSMAAEGLLMHLLHHINGFPTPAGVDQMVSTCSELRDGDDLANGDGAAETDPNAPASLSFVFMDSMIFTLVGSLDSPCVRYIVRDMTGLFTWEIMPAATGITTQRRTKKAMSIQQEAVKERELLVAGDGGNSRGLEQFHLHRAVASVRVELKAAANDNAASYCQTCGGEKPRSAPADPANTLGSKLEVLQVSKPREEAILSNSVCNSRSNYVFHEEDDSAAAKGNAEAGDKKKAGAGSGASVESDKMPMSGGGNRDERQERLDRIAKQYEERNNISAVVVTPVQPTKPVIRRCDCQRRSANGNAISICGLFDMDEREPNIGNLDDERCLLDLVLDSVPMVFRDCAGDTTDKTLLGGRYAMLKYNHMDMEDGTNPLVNDSAEIAGFSFLQRLIHDEECYAQLKAFLLKENNGPQGKDLAEFCDAVKRFERAMVPSDRLGQACAIFWEFFSADGGRSIQFPATITLDIQDQIQRVQKALKVGQSDQWGISGLVFQPAMSHVEHEYFELSGLLDRYVVSLEQPAQTNGSDVKSNGNASAPTAIPSQLALFDAFSIMELNARISHLALTYRSVDELQLTLSRPKPFHMTTMEDPSMRVGALDVCRMFLAQSSMLPSSTGDAMMRRRFKLLENGSKLERSLKHLDKSPVRETMKIGVIYVGLKQRSQQEILRNDRGSKAYERFIKQLGWEIDLLSHRGFIGGLDSNPRSLSNGRTSLYYATAHSEVMFHVVTKMPTKPTDPQQIDKKRHVGNDYVHIVWSENDAHDYDPSTITSHFNDVQLVIYPLRRSQRGLYLVKVHSKDKVPPFGPIQSGMVIPEADLVSLVRQTAMNANRVCRSQTMVYVRPYPTRKKLVDEIVERYAIEYQESQLLSMLFANPSSSAPQSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJJ0</accession>
    <name>A0A8K1FJJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Upf1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_009148</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJJ0"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.230:FF:000005">
        <property type="entry name" value="Regulator of nonsense transcripts 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="13">
        <location>
            <begin position="103"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="11">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="11">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="11">
        <location>
            <begin position="171"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="898"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="951"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1053" mass="117250" checksum="7DE14B52FFFFE8E6" modified="2022-08-03" version="1">MDHSFSYDPYDDGRRMQHTQAFQTQASQASQGMYAFVDPMEPLATQPDDGGMHTGASYEFYDQYESSTAAFGLTGDETNALTGEFQHLNFEDTVDDEQLDYTSKELPAHACAYCGLHDPASVVKCVSSDKWFCNSRGNTSGSHIIQHLVRSKNKEVSLHPESPLGETVLECYNCGCRNVFLLGFIPAKQDSVVVLLCRDPCLQMNALKDMSWDMSQWLPLIEDRSFLPWLVKVPSEHEQLRARQITSTQIAKLEELWRENPLATVEDLDRPGIDDEPTSVETKYDDGYQYQNIFGPLVKMEADYDKKMKEAQTQDGVMVRWDIGLNKKRNGTFSSNRPDSDLRLVPGDEIRLRLGPSAAMIYGKDWEGSGHVLRIDESDVTLEMRSNNVPVEISDGYLVDFVWKATSFDRMQAALKTFAVDDTSLTGYLYHKILGHDVDVQALRVPRSLGTRVSAPGLPELNPPQMEAVKGVLSQPLSLIQGPPGTGKTVTSAAIVWHMAKQNMGQVLVTAPSNIAVDHLTAKISATGLKVVRLAAKSREAVASSVEHLSLHAMVKSLDSPDKADLRKLMQLKDDQGELSSQDEKRFKALKRQAEREILQAADVICTTCVGAGDPRLSNFRFRQVLIDEATQATEPECLIPIVQGAKHVVMVGDHCQLGPVVMNKKAASAGLNQSLFDRLLKLDIRPFRLRVQYRMHPCLSEFPSNTFYEGELQNGVGTSDRQLKNVDFPWPNPNKPTFFYICLGAEEISSSGTSYLNRTEASNVEKIVTTFLKAGVLPAQIGVITPYEGQRAYVVNYMQRNGSMRSQLYKDVEVASVDSFQGREKDLIILSCVRSNENQGIGFLSDRRRLNVALTRAKYGVIVLGNPRVLAKQELWNNLLNHYRDHQLVVEGPLNNLQPSYMQFPKPKTLSRDNRSGFSRQRNAPLPPIDSRFDPRYDQANTSSSPPYPSQSGSGYPPAAPQRGGYGGQQQRAGSRRGGPSYLGGMGPLTQDGMTQGSMGLDGPFTQVGQTQSFSQFSSADKFMMSQDYGYDQDFKSQNIPMSQDIRQGDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJR6</accession>
    <name>A0A8K1FJR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004110</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJR6"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="13">
        <location>
            <begin position="41"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="196"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW66345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="31573" checksum="38AD8ADA13D1F62F" modified="2022-08-03" version="1">MLRIFKERAQRVSSALDEQQTREYHSKLQLMMSSERMLENSMAVLERQQQRLLLLRHAMWCTAPDETCVAAPNCGETKRLWEHMSACQKPTCSYSHCVSSRYVLSHFQQCENSKCVVCQLLQYAVEVKEKDGSLVMNADRALRQIQLATEWQYRFAATVPELTRDETHQLEQIQVRLRGINLKTLYLNSKQLEGHAEQLGNQAKAMMAEVRQLTQLCNSTHHPDLKKQYRDLLQRKNAMLRRITERLQKSTSQRRVLHHVICSRIKATTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJW5</accession>
    <name>A0A8K1FJW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008013</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJW5"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="117" mass="12850" checksum="D54BF7A00ADAD17E" modified="2022-08-03" version="1">MPFIKVATNLPRASFVANNVLKAFSTSLTSVLATHEKAVMVQLEFDQDLILSGSTEPCAFINVRTIGKIDPEHNPKTYEALSATVLEQLNIPANRIFFNLDDIQANNWGYDAKPVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK89</accession>
    <name>A0A8K1FK89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK89"/>
    <dbReference type="OrthoDB" id="128712at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="818"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1000" mass="110461" checksum="3C5C691D70B71C0D" modified="2022-08-03" version="1">MMYSSRPSSSRSRREPESSSGNGPLTAERAMMEQIRSKLERSQRRLAREQAQTSSQSSYKSGHTSQVGSSRYFPPDYKSGKAAPVKSMLLEDFSMLASSSGGHPPPSTRRDPYEYKSSRAYDSRRHGEPSSSSHHRHHHQQQSSSQYRSRAHGLPPSSSSRHHHHQYAAPMSNSSFLVYATNKGSVPLSSASPSAYRGPSSSSSSSQSHHHAPPSTSSRVPPPPTSQAQPPVSNSILKHKSSFRRQTSPDLDDSMVPAPPSSRVRFEDLVGMEETGSYSPPRGPPKSVRPPPLLELDDEDDSDEFEKPKKEEKKLTPVMRTRKTTEKEKEKEKTRARPKPPLLHSPMATRKTATVMEPPKSDINVSAFDQFMMRPRRQTKEVREPPRSPIAASAMAPSNQEFDVVRAIEPTPTPTLPPAPTPTPAPTSMPEDIVLPPQKTLSSTISSTFIGDSSMYDEIDDLNRVMDEKMELKEMDDTTEEEETPEEETAVVDDQWSEEEPLDDPQEPVGLVEPPEEIGLVLLPYEPELDSVEESPEEDEADVSFEDKSPLTSDDDNNRPSVPGKYRSFEEVDARVFERSPVKAAQRATGNVPTIDEMEAKAAEQPQVEQQQLSDDDVENFRDDEVPKGIGQFMTRRSARYDPNDDYLAYSMTPTEVDMLADDDDAMIEYYSTDEDDNRSFVSSIRSLQVPHEREVAGTTRWSLLPSSSSVRDSPERTGDGTRHSSVSLSRPSENHVLIAEADPSRTPLGGSSGMRQPARPPYTRGASEQSVNAAPMTAGPRLSNAMYAPPPPSIRPASARPTVSRPSVTRSTVQRAPMSTAPMSTRMPMSSRAPMSSRAPPPTSTTAFPTSSRRLRPKNPMQLRKALPPSIGALSGLASGPVTFDLNESAFYAIVWQTGEFGFSFQRVYLAVDGDDSSSRLMFLRMLLNTERATCASFRNVHVGDVLIQIGDTRVCDLPLANAGASALTKYFTELRSQTPLRLVFQRTDPSSWEGGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK96</accession>
    <name>A0A8K1FK96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_012001</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK96"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000113">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457179" description="glucan 1,3-beta-glucosidase" evidence="18">
        <location>
            <begin position="22"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="19">
        <location>
            <begin position="144"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW66885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="445" mass="49688" checksum="A5EE493838A4BA61" modified="2022-08-03" version="1">MFVRLLKAVGICAALVATLAAAECDDEYVNPAVQKGYSFDDLVNTTTPSQKPSTAPSPVPSSVGSATPPASGHVQAKIRAGEVKSRGVNLGGWLVTEKWMNAGSDIWNDVPAQYSGGGEYVTMKHGSNVDDRRKRFTKHHDTFIMENDIREIAEAGLNTVRVPVGYWITGADPSDISNKGEWKAYPQGTLAYVDRLIREWGVKHNVAVMISIHAAKGSQNGQDHSAPAEPGKAYWSKYQENVDNTLYVAKFLADRYKDDAAFLGLCLLNEPNADTSESVVNQYYQDAYKAIRDTGNDCILSIMPMLYKQTAENLNGFMEAPKYTNVWVEWHPYFLWGYEDVSADDLVNKSILQTFDAKIKKWVNRAGANKMFFGEWSLGNAGQYKNADSDGYKKWTQAQMTVMNQASAGWTFWSWHIEGDDKNYNAWSLRSVLHRDALKQIVMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKC3</accession>
    <name>A0A8K1FKC3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKC3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="141" mass="16002" checksum="835728F15FBBE828" modified="2022-08-03" version="1">MRPVISAEYDRDGEQEIVLNPPPALRRETLQQHTQDPPQRGTSIAQKEIPSMGLDHSDDEFSSLDEEGSSLLQRPLEELERELGINFNDLSEEEKDDDSDDEELEDDRAQLLLRAKKLLAEQSLLSDDSDDEGHGYESQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL23</accession>
    <name>A0A8K1FL23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL23"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="525" mass="59620" checksum="7BF6DF20E173AD54" modified="2022-08-03" version="1">MKALKIKNRCESRLFFAFCTISSCKCSICESWIKHEKKPIVGLGAATYGYVQVEPFSERVERFCDKWQCIGACFFDSMPQVIKKEMLVRFNEEKNYKVGNGRGKLRFTHTPEALLAQPGFLHIQNFGCSTLYFVFSVVSKCECAVCQQWINREEFRAVDSEETKYGYFQVNGLGERIEHVCGQWNCVGACIFNAMPETIKKAMLLAFDKSKGYMYGNDRAKVHFTDTPEVGLTPTKPEATRPPNCIHVQNLGESTLFFAFCTTAWCKCDVCQSWLKLEKTPVVDLGRATYGYFQLEAFGHRVDHFCDTWSFIGACFFDALPETMEKELLLEFDKRKSYSFGSDRAKLRFIHAPTPPKYVHVQNLSGSTLYFAFSTVSECRCENCQQWIQLERLPLNNAQWRVGRFVVEPHKAHSVRTCDQWECVGACFLDAWPLELSKAQFGRFDRRQNYRVAGGKAKLCFANEQKSPQSRRSNQEAAVEVEIVGAGAMTEIGLELLKIGIEADPETVAESVNTVVEVASSCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLY2</accession>
    <name>A0A8K1FLY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011256</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLY2"/>
    <dbReference type="OrthoDB" id="539158at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="69"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="680" mass="73996" checksum="70015C2B82B68436" modified="2022-08-03" version="1">MAGMAMLKGKYKYMPLSEANVSPVMVSAYDGQHVYVTSGASSLAASSSLSSSSSAVASSTADAKPEIRYTMGNYLGGGIAGIVYEAYDNQQQRQVAIKILNPVGYKLCTPSALRRAEIVKKGVPSSPRGLTMENVFWVKLPNKRDLVACYVDARMLPVNSGGGGSASTSSANAAATMVNVTPQMLRELTLEMCVALWRLDGEEDDDEHELAPHDMMEHGEEMKESSSRLHDDEELEEDDEMMLADREWRRRPREEEVKVGDVVYKIPAMPAKYKAFLESRKTIYREIAHMHKLTGNSISGPIGGGHANVLKLYDVLELVQPSKSTIFLVLELAAGGELFDRIRAENGVDDAIARTYFTQLLSGVLFCHQLGIVHRDLKPENLLLSDTDVLKIADFGLSAHFIAAVSSGGSTGVEESSSPPTGGFQFPEMDEDEDLSSLMIPAARFRRLNSIVGSPHYVAPEILQNARYGYDGRKADMWSIGVILYSLLVGSLPFGKDLQTCARYLKFCEWIRSLPCDVQTGKLVFDTSVYNAGPVRIPSSTSSVTKPSNMDDEDERCSNSRFALVHPNSQPTPSMAMMMNSSSAGMWSFSGMSPAPSKVDAVHPSNDSWSLNNVSAGFLPNGAPAGRRGSRVVTFPSWLFPEKLAPSAVFLLASLLHPEPGKRVSCEDACRSAWVAGISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM98</accession>
    <name>A0A8K1FM98_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="7">
        <location>
            <begin position="67"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="6">
        <location>
            <begin position="705"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1489" mass="165252" checksum="F419AD482BC35C6C" modified="2022-08-03" version="1">MATDALDMERLLKGLAEAKHRVEQAVLEDSKFPDLLDQLANQSEPQNYFFEPYASQWCPQVVKKGSLIPLPSVIATSMEEEMQSLTLSGLLTPLDHAWTSVDHRLFLWSYKQRGRFVVFEFDQPVVAVGLCVTPRAGVFTDKVKHLLVVATTVEVVLVAVLYEDSQSIASGLRLQRTKLSVSTDNTVVRRIVTTAAHGRIFFGGSDGGVFELLYGPSTGTAAAASSALGFDASLFIPSFLQRSGCRKVTHTSRVANYLPSFLSALASSPGKLTEFALDEDRQILYALHEQGDVDVFDLGVHGNEMKLVCTLNLLTDGAKYARENRRTRVSCPDERIFQQANLKIVSLAVVSRNESALVSLVAVASNGIRFFLTVYSRRAYTVGNTIPPSRRPTRLETLYIRLPPPAVSISDAPPYHAKEGMQPGFAPGKSPSNVHLAYHKRGVLLLVDGPKDQQDQLVGVTHDPITSSLAATPATRGKPTVRESVALESCIGKIVDLQELGESAIERSQRMRDAASAATRNGSSTGSKRSFEEMTNGFTSNIMGNDMVPMVGEMAVQYSDPSRHFLCLSSAGIQVFKKIRPIDQLHRVLLLSRGSDLKATLAPFIRSFGEIQVCCMLIALACGVQSDPLMADGTTAAAAAAASVSMVHRAGVKSDEYIFTTAMQGIFECGQLAQARSAADMDTSSQSATGSNNTRIVLTTDFGMSYHHDGLVMFVCRVLRPLWFVKSIGRRVSNNSSTYELAHSREKLDEIREILFQLRQLMESAGPFAVSISSGSILENSIDWNDADASTRAAELAGQYQKHRNEEQLKREMRFKAEQRSLYFIYQLVLRSIEAISLLRFTMEHHVPLDETFARLGFGELVSSAEGSSAAKTMIKALMKGRNENNQFLVKQLREQCPSYFSVSDLWHYQGYKSLAMAKLSAPSGRKAHLRESLSQFLNACHMWDTGDCIEVLQGICDDYALLNFYEGVVKLSLACAKNFHDAAATDLTGVKLTWKRNCFGCILLALQRLLDPAGRSPQAVDDMVSLDDEARGRFVEEVLHYALASEDSDFHELLYTWLYEHGHTHLLTSIRSSFIEDFLKEKDQDLLIKMYMEQQKYLVAAKVWWSRAHEDSEDISVENNPDILKRQYYVSKSLGCLKSIEDVSEAADAIREVRDVLDVLQLQVRVLKALEQATVELEASASSSSSLSTSSIEAEINERKTDLQLLTYKIFDASTLYNRFASKYDMWSECLHIIHACNSEEADVIESLWRKIIFSVMPPSSTSQEFNVWRADQCDLAGLTASQPSNAGSMASSFENGYWIGQLQGNILRLGKSLYTDGAGADRGGAAGAALSNFVFPVGFLAKQLERISSWYLRLTQLPAFSVSSSSVDATTVNWVLRVFIDVGVPHRSLLSYYERLYHEQGSVEWTLHLLQSVHSILSLWKKHAISPRAGQDQLQDYAECCPHLVAMCDDIVTDLQALSSDGRREVAILLEKFRRYKSELLSFRNPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMM7</accession>
    <name>A0A8K1FMM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UTP23 sensor motif region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004199</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMM7"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08553">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="8">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="27224" checksum="3D80A56F3013B26B" modified="2022-08-03" version="1">MRYLRAKGIRKALRQFHFLCGIKPPYKVLIDGNFLAMCLQMKVDLRERVPKFLQVKPHQVEYYIPRAAVNELELLGEAMQEAVDLAKSFHIIEERDYGDDATQSKGDGPVDVTKVTQSIIGDRNARKFVVATQEVELRKVLRAVPGVPLIYLNRSVLVFEDISKATLAIVRQEEKAKMAKLDVNEKRKLESVYESDEKDKEEDAHQRKKHRAKAPNPLSCKKPTKKKVRSKKKGKDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMT1</accession>
    <name>A0A8K1FMT1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMT1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="213" mass="24349" checksum="2180C0FE3426C5F0" modified="2022-08-03" version="1">MTELRRFALFDAAASGDVATIERFFRQPSMQPAIERVNQRFRNAFDYYVERNDSPFLTRPSPPREEWHIRIHPQGLWELELLFVKPAKHGHVRVFAWFCSDVATEIIGDSMRYLLYMLYSCAAQFAPNCAEITEAILLSHLFASFNDVVRSLALSMMLGSAIKNKRANAIRVLVAHGALVEEQDVSEFMRASLDMETIQALEDGGVAFKLRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMY0</accession>
    <name>A0A8K1FMY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMY0"/>
    <dbReference type="OrthoDB" id="166585at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006624">
        <property type="entry name" value="Beta-propeller_rpt_TECPR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19193">
        <property type="entry name" value="Tectonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00706">
        <property type="entry name" value="TECPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19607" checksum="F73D1AB4C193F67E" modified="2022-08-03" version="1">MNGNLMQISFDGSRVCGVAPANSIWCADDNPNGALNWRQVPGGLKWISVWGDFLWGVNANDDVFVGRSSGDPLWRQLQGKLKQISSDSKQICGANSANEAWCADECIFTAPKWRMLPMKLKQLALINVRCTASAPTTRSGSRQLPGNFRQLDIEGGRIFGVNGDTVNYHKWLTPPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN21</accession>
    <name>A0A8K1FN21_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TatD related DNase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN21"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008310">
        <property type="term" value="F:single-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000005">
        <property type="entry name" value="TatD family hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31123" checksum="813D8E100D2885E4" modified="2022-08-03" version="1">MSSVPDSETVLFDFDANLTHDDLVQDAAAVMERAASVGVTEMLVPGATLDESEATIALCRQHPTNLFPTAGVHPYHAEALPTDAELERLRGMAAQQDVLAVGECGLDYSPSFPDAKWQKAWFTVQLELACELQKPLFLHERLAHADFLALISECQAKFNGYFPPAVVHCFTGTEDELLEYVRRDFYIGVTGYICKKDRGAALRDMLRHVPLNKLVIETDAPYMGFPKCRSVESADKKKQYPNVPSALPQVCEVVAQVLGKTPQDIAQITRANARRFLRLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPH6</accession>
    <name>A0A8K1FPH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF4832 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPH6"/>
    <dbReference type="OrthoDB" id="6085154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032267">
        <property type="entry name" value="DUF4832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032379">
        <property type="entry name" value="DUF4874"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16116">
        <property type="entry name" value="DUF4832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16173">
        <property type="entry name" value="DUF4874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456778" description="DUF4832 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4874" evidence="4">
        <location>
            <begin position="101"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4832" evidence="3">
        <location>
            <begin position="281"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="51071" checksum="05A6BBB5B0DE4450" modified="2022-08-03" version="1">MLGFRHLLIASLALAGVANACKTHDPTGAPSSVPTSVPTDVPTSAPSSVPSTAPTTKPTTKPTTKPTAKPTTKPTTKPTSKPTTKPTAKPPTAPTPTKHINPDRGFFHHMETTTSKFSPLTVNELNEYSDVSIIKRIYYMDNFKTGPLSTAILDSFKKDFSVAKEAGKRIIVRFAYGADDANDPAEAIVLNHIQQLGPVLKEAAPVLLIVEAGFIGKWGEWYYSNSFGSPEKGELSTANKEARIKIVQGLAKSVPTEVPIAIRYSGWVSTLSQKDASLKGRLSMHDDCIFADYNDLGTFEKASENTHALPFGGGGEACSSSYDLGSGKDCTAFLTALQRINATYVNLDYDKAKLSQYSKCDYGAKIGYSLTAQNPAVDCSSDKCQASVTILNEGFARPTRTKTIQLHCDEDAIAVNADFRQLLPGSSLTLSADFDADSCDSLGVSFMDPAFPSNAKFAVALQNAVAFDEATGQNRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPM4</accession>
    <name>A0A8K1FPM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPM4"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="51"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="441" mass="48770" checksum="897CB27895F9C8A5" modified="2022-08-03" version="1">MMTMHMMQRVLRRSGANMRPRQSRAISNRVSGIGNNVFAEISLLAGQHGAVNLGQGFPSFSTPEFVKQAAIEAIQANNNQYTRPGGQLDYVKVLADMYSPLFERQLDPMKEIVTFNGAQEGLAAIIAALVEPGDEVVILEPYFDAYKTISTLLEIQTVGIPLKFTPSTDANTPATSTNFHLDLEKLDKALTPKTKMLVLNTPHNPTGKVFSREELEGIATVLRKHPHVTVLSDEVYEFMCYDGLKHERLATLPGMYDRTISLFSAGKTFSCTGWRVGYAVAPAALAGAITKAHSVIPFCGVTPFEVALASCFKQIQHNGYVDELRTTLQTKRDRLVSALQSANWQPIVPEGGYFVCCDVSELPFFQEFANRPIADDIPKTEYPDYQFAYKLCSDAKLAVIPTSPFFTKAEHQLTKGLVRLAFCKDDQTLDDAIRVISSLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPX3</accession>
    <name>A0A8K1FPX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1409" mass="157690" checksum="A612A34F5CD29CD2" modified="2022-08-03" version="1">MASRGSRKRPRASTGRSLREDVLALIQRCKPQRQSDHEQLLEAYNALWTAFRRVVGPQLGGSQCETDAISSDRMRMETTQRLVELSKRFDMSREILLRCCVRSIRVDHGRTQGLTTVLWLWWLHSLGIWRLEDVLMAMAVHAREGFASTEAIEWFCLPCDVLLEATDVAIVLDNENGTMSTHSVVQQMVWYLMRVAFVNPATRDEKSFAPSSEYAAITRTLVRLILTSWCDVQASTFSMQATMVLFQRAASIVQASVDKEECDVVRTFVRENVQTLLVSVAEDPATDEMIDQLTRHFQLCVSAVDASQLLWSIWVESAAKEETQTRRTKSKSARLARIIAQCATRDDEFTSHALTMAHDLAREAINTSDPVRLRQSFELTAAVTHRDDHQGEEEDLYASWFRAHFALTDSSSPSECPQCLRSQSGGSCTLISTKRHLLFLCAFLLESDRSEQRASHVFAHLSALKTHQNSEGASAVSALLSDFCAQTRARHAELQRAEETSRSQQASDAQGCGETDKKRGVKYTSSTIATVQELVSAFGEDKRLPPQVNRWKMFQPQQWKTQLLPCCLDVTFWTHEIVGENDASAVSSTLVHLSGLVHTLAKQHVITVEQYEAFLQQMEAWIQQNHRQLTSQRHQRRPGEAVAALRSATMRYEDMKHLVHRNTNAEYEDVADAFVVAFEELVDLTEATRMTQMRELWELTVGARDLVTTTFKQFVEQHLVLWIRLLSSENAEAPPEARMEIMEAFCDFALSQATSVSAHQVLAIASIGALAGLLASLPVCEIMATKWIQQIHSELLHRGTGPLKSIEPLEGYCVFLAAFLVGFSRNQPTELPPQVVLQTVLPPDLCDAFVWLSHHLTTWWSPSSEASMSVWHGIAQCFDVVRPNPWFRFVTMTSRLSSASQWEQVFRWELCGFGHRVLRSNQLSLLSLVRLELELLAAWLQECHTKLNRSPIVTICCVVIETLVSVTTLDAEMQSQEALNGLVMLFKDACALSQSPVQWISERQMLLEALVTAILSTQEGRSLSVLLYTLECMQVLLSSLNADQDAVIFVSEARILELLRNAGAIIESMGTIQTVVVQNATKTLFRLVQRVQASLGPQAYQDIPSILWTQWSLDTSLSASDVQFTAVDGIVESLRLFHRQLGAQNALFAPVNGAKPLSSRAPGSVQIRIQSLQWEIDRHLVHVSSGDQSEIFAMTLEATLTRHSFASCVIQALSPSQAPLSAEAACEIADCCVSQWLLCNSKTSESQSTSRFLYEMTLVHMLVEIATGFATVGRRLLRQSSEISGLRSLLWLLMLSIASETEQIDVLLAHHASLWVNSFSGAACDLMEMVDRPKASSEEDSSVLRTLQALPAFRDTLKLVLDRVLSFAAKKHVDILDVELPARVAHYFPVLEAAVKRVPVLCIPTFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQT0</accession>
    <name>A0A8K1FQT0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ankyrin SOCS box (ASB) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQT0"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051573">
        <property type="entry name" value="Ankyrin-SOCS_box_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136:SF15">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136">
        <property type="entry name" value="SOWAH (DROSOPHILA) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11943" checksum="27DABF7215965136" modified="2022-08-03" version="1">MNGDTALHIAVLRSAAACVEFLLKRGADTGIMNANGETPLCLAASTYRAAMIPLLAEFGADIQAQNHAGSTPLAQCLRTMSWINELHPIYETAYELVVCGASKFQNCCWSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQX1</accession>
    <name>A0A8K1FQX1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQX1"/>
    <dbReference type="OrthoDB" id="68033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="29499" checksum="9274B0271D0FCE1A" modified="2022-08-03" version="1">METPRESETPTPTPATVKQVETSSPRRSPTPTTNTSPMEAMRRAPHTMKRSRKGFSVGKQRILTIEAAVEGDKDSDEANTEQKHKNDSTSRASEWWKLEYRAPPPGHLGAHAVPVVAHDSSFQRQRIVRTSSAESTGRQQADKHTSSTESVIPSSRNTHETPERAHRRPACSEKDRHSSPSQKRKIIDLQDYDAAVLASMVVAKELKRFHEPSSEQPSPAPSKARPMATTPSKLVRPLTQIDIQGGSSSTAPQETVEDAPSHPQAPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1X1</accession>
    <name>A0A8K1C1X1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000169">
        <property type="protein sequence ID" value="TMW54924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1X1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="133" mass="14650" checksum="E1AFE042322CC07C" modified="2022-08-03" version="1">MTNESASNYEYTIFAGEASVHVYRRAQTPAANAKTEPFYTDEIVQRKDNYAVATLKLALFHILNFVYAAFAFIVAVTIVTLSIGLLPLLGLGAFVYVRSMPVVGWLANIDIALANRITPIERRVALNKGNSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2S5</accession>
    <name>A0A8K1C2S5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2S5"/>
    <dbReference type="OrthoDB" id="93059at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="244" mass="26552" checksum="6665F47F41079FA3" modified="2022-08-03" version="1">MSSNREVKATTRDLFAASERGDANAVATLVKAPDVDLNWHCQQAYGATALLVAITNGFPDVVQLLIDAGAELGALKTPDRNSPLHEAAFRADPTIMRMILERIEQNGNQPIASLIDMQNQFGNTPLHNAARTGSPECVEILLKADAKPSIVNVNGSLPLHHACYCEKSNLQVVKLLVDAGLDINHQDAQGYTPMMVAAKKNQTEVIDYLRGRGADLKVKNQFGENALHFATLRENKGAMELLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2T6</accession>
    <name>A0A8K1C2T6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2T6"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF1">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="46735" checksum="D9C67BF1D090CECE" modified="2022-08-03" version="1">MALPSVGVGGDALVKFFVQFVFLFTGVFSTCAAQYVFYQGAGDQKAMLLPLCNYLGMMLVGLIPMSSSDKAKTEAVPTSETTATESMRQTPGHADGMELTRRQVFESDASNSESETDTDSSSYSSPPSSSPARLPSRLPPRLASPAPSDLKIRVTKSTVSCSMSSLQLCILLSVVLDFAGCIFSNIGLAMAGSGLYQVVYSSVICWSALLSRIVLKKIVSKEEWFGIALVTFGLAFSAMGASGPGHDSYVVLMGCLNTLIGAGFYGGNYVTGEYTLKLPARPQPKELCLKIGGACVAIIAVYQLFFVLPVWDELVTNRIEEAHGNTNNILLALVGYTLSQLAHGLTYFMMLGSSGAVTTGIMQSLRAVCVFAISSVLYCSQQESQCFDTKRGIATLIVVSGVMFYSWAKSQATVAAPVALPVTIRRKDKLISGKNLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2W6</accession>
    <name>A0A8K1C2W6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2W6"/>
    <dbReference type="OrthoDB" id="64928at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36749">
        <property type="entry name" value="F7O18.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36749:SF1">
        <property type="entry name" value="F7O18.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="297" mass="33503" checksum="CB918F0A4143C111" modified="2022-08-03" version="1">METTTDASMDLYAGLTLPTKKQRVRDGDDQKAEDKTNATSPIGAEKIEKSTQETEEEAPPAKRQRTEVDVATAIERLKTHMVVDKKFDKAAQLFTKLVREKLTTENRMLFLDAFKELISAKGATWSGKPAFAELVRTLIGRQDLYTEEEKASYFDDWKLIAVTHAELFTDDTFEFARTVKLVKARVDAISEDTDAESFAQLMPLLRTLFSRHSVAWAKTPVESVLHVCTRNRLLFNESDRDQVDQWTAAVLERRNASTITRSSASDARRNLIAMDGKASQAGTKVGRSNHPLFNRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3R2</accession>
    <name>A0A8K1C3R2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3R2"/>
    <dbReference type="OrthoDB" id="60105at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1165" mass="131441" checksum="77398A17EA2A2A98" modified="2022-08-03" version="1">MTVPPPEDYGTTFKDDELVVLQLLEEIRQLIRPSRSNAVASAARMRAAARLYLDTRDTFEVIESHVEALPPDRPKFLRKLSKRRSVTDASPRDSVVKVDPSALNAAATCVAQPPSPTESKVTSPRLSLVVDQVLSSDGPVAASTESVDPANDALLDRIQDMFRHLGSQLSRPILDELRHRNLSMQTVLHYVRFLPPDSQWTAYLEKREEEVRQAYRPTTSVNDLPIRRLKENAEFVKEQIRKDVNTVCLFAPDGTLSTIFGDDINTDNEAVAEKFEALITGVYCSFLKSIIDAKMDQLLSLSDQWQQDMAIMAGGSPAVIEPPQAQLYTRPRKFRSKIPIFPHLVTAIDDRSPMLPPGPGGQPGRILVADLYHVGIWWQKSILAATDRDITTTHTDDVRGISGRIESLDGRMFVPLTLDTSQDFLRRYARGGFAKWLNHRVLVNNGKDSIWVEVTVTEVEDRKCKLQLKRSIQSCAEVEGWSKLLATNEWLQLKDLRICLVPSSPGFRIQMGHKFRVMLDIMQSVVIEISSIFPNNVLEQKVGKALWQSVESSIARGEHIYARYFRSVLNQDLQPKTNPPLPSATSSIILDRSPSIAMSTPSMRNLAAALEHSALNQSIHGSISGPPPSSRPSMSQPRLSLTSTMGSMAKPVEAAYFNDKGIYNHQLYITDPPLRALVTQPKISQFEKLAHHLLEEKEMIGACIQANTIALSRAFAQVLQEKLTKLVRSLQIRLEQEDTNSLETVLTEYAHACRFLYTWRICRHELDTSARQRRAKRDTSNIHSEWVDRSFDRMESLVGVMMQMQVQYVQRVFFHECSSYILPGIHEQDWTSNKPWFSNSKCTHSVQFLIYRIRVVFEGTVLNVLSQYERALGVHEKMQELSVWLVLDAFACVLAAYEHLCVSRARLTQWKMDVIYLICGVHATLRLLDKMIAPKAPQSEGRGHKRPTTELREISLRLLTCLAIRTGPASEVVQEIRQKVAMGDNGLPRVDAITELEAHVSTLQASIGFRRLGSSTLPLDEDDRLIWSMHHLFPGVEGKQLADVRLNWGSLIARSSLSLEEMLVSLRFRHELGNWEYPPLTEDECAARDQLQQCLQLVEEHLHSQEPPPDEQESNDENHSSETASTEPGHERTTPTPPPPEASEEAATHEKVVQEAGPRALPEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3U6</accession>
    <name>A0A8K1C3U6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3U6"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035439358" description="DM2 domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="4">
        <location>
            <begin position="116"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="3">
        <location>
            <begin position="241"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="3">
        <location>
            <begin position="374"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54764" checksum="9F9E4B58692D803A" modified="2022-08-03" version="1">MNKRGQLTRCGHIRLGLVVIIALELATTLAKCGTDPEGTDVRVTPPGEADSEDSLWWPETFDSSLDADFVFVLWKSRGHHTSEEDNEDVVPSKRNSNTAYDWHDTPTLDSETAVTHVDEDQLVQAIRAILHGADLEQLSRRMIRKQLEAQFHTELSAYKDKINETIIQIIQEQQQGDEEEEEEEEDNADDDEPEPSEEEDDDEEESKPKKKAKKAAPKKKATTTATKRKRASSGTGNSSSAFNMLLSLSPELASVVGTDMMARPQIVKSLWEYIREHNLQDPSNKRVILLDERLRNVFKRDTVTMFSMNMYLKRHVRKPDELPPGGWSEIPRDGLSGDEEDEDKAARKKASATRKKKKSPSDGASDEAKPKRSPFNAELALSPELAAIVGTDRLARPQIVKLIWEYIRAHNLQDPNDKRVILLDQGLRNVFQRDTVTMFSMNKYIKRHAMKPENLPPGGWDSVPRDGASSDEDEDSGKSKKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Y0</accession>
    <name>A0A8K1C3Y0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Y0"/>
    <dbReference type="OrthoDB" id="549039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41588" checksum="B8EF1EF95223FBA1" modified="2022-08-03" version="1">MTVSPSLHVLTSPVLFRAIRAFAPRTPWSFLAFEAAHRGKPHRTPRSLPELAIQFDDFPALREFYALWSNPDYRSWNKLSFNHTVLRAAQYKQPEMLRFLLERDLEDDEFSWIMARAIGYRCLEILQVLYEFHPQESQAYTGVIDYLVHTHELAVIQFLVERGIGRWTSVAFDGTFLRGDVDIVRLLLKHRVAEPSIEAIDRAAYRGDIEMIRLLHSHNAPCSTNATDYAARRGHLEVVRFLHEHRSEGCTYRAIVGAAENGHLEIVRFLVEMRHEASTAQALYHAVEKDHDTVVRYLIENTMAGRLSEAKSRAILFNHESIASMIEKMIANGIKRVDVAQQGREEDLAGKERASKRSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4W3</accession>
    <name>A0A8K1C4W3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008820</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4W3"/>
    <dbReference type="OrthoDB" id="165938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00538">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056858">
        <property type="entry name" value="VSR_TRX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702:SF1">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25011">
        <property type="entry name" value="VSR_TRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471299" description="PA domain-containing protein" evidence="12">
        <location>
            <begin position="30"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="63"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting receptor thioredoxin-like" evidence="14">
        <location>
            <begin position="207"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW56172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="739" mass="81103" checksum="1321C32413C8EA45" modified="2022-08-03" version="1">MGALRCRRVYARLVATCAALALCLHSCEAALRVVVPTQANARPIEHKLAMFGRPEYGKALIAPIVLAPETNRRACGEFDREQLATAMHRYGVDTHSDHEADGAFLLMVERGQCHFVEKARHAQTAGAVGVVIYDTNKEKQKLPVMADDGTGGDVHIPSVMIHQEDATALMKLMNSTSKTILSLSWDVPHPDGRVEAALWFSSRSSPSLHAFIDRLRVIAQALGDSLLLTPYYDIHEGSTWGCSAGDDNKREQCRDLCVFDGEFCTYDPERDNTIGLDGRDVLEEDMRQLCVQEYALSKKDSSLFWAYVAGFNARCSPEKATKDEFNAACSRTVQEALAIPPRTIDECVQTSGRKLLKAQAEAHHTFHVINFPEFTVNDVPLYGGLECDESISLASCAPLKMICTGFLDGTIPQACHESYWKSGCTPPLERDDCGVCSLRNGTKWNQECVGCDGVPHSGKRQDECGICGGDGTYDVCGRCLPANDKARGQSCMDCKGVPNGYAKRDACGVCDGHGSFDACGLCLDATDPRRQNFVCHTMEDPDAVTSKIELQGLSMKTFHRDVFGSFQRAVAFVVDVKASEVVVKTVDEVAQPESHTPSTVVVFFVACPDDECRERVTTKLQEKTAALTITMKMKNDLEPLAYGTQAAEQIEHVALHSVMSTATTTGNHGISVAQESWIMGIAVACATTLAVGLIVIKLRDDRMRRDFHQLFARYTPLTAMDYEEEQEYGRSGRVSAEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5B8</accession>
    <name>A0A8K1C5B8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_006854</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku80 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5B8"/>
    <dbReference type="OrthoDB" id="30826at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00873">
        <property type="entry name" value="KU80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.240">
        <property type="entry name" value="Ku, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024193">
        <property type="entry name" value="Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005160">
        <property type="entry name" value="Ku_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036494">
        <property type="entry name" value="Ku_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014893">
        <property type="entry name" value="Ku_PK_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03730">
        <property type="entry name" value="Ku_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08785">
        <property type="entry name" value="Ku_PK_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101420">
        <property type="entry name" value="C-terminal domain of Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="15">
        <location>
            <begin position="7"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="565"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="753" mass="83577" checksum="9CC9CE5C87A6C64B" modified="2022-08-03" version="1">MSRTKEATVVLLDAGASMCTPLRERHDVKFKEHKALTTRFDAAVAAVESLYQQKLFFKPKDEVGVVLFGTEETSNQLNEDQGEDEYTNVTVLSDIDTPTLSVCEKLQTITPTADPAVKVDLLNGLIVALDLLFRRTEGKKYEKRLLVLTDAASKIEDASDIESVVEMIKNMDVKLQVVGIDFNFTTDKEVDPNAMKDEPMDQPKQEPGDGVVSVKEENEKMLVSIAKEVHGEVASASKRMQLLAQGMKKTVGQVTKFRGPLEIGDFGIPLYCFLKTKTATLPTLAKESQVSHEKEESGKVRMDRRYTSPQNPDEEVPPEQQVKAYRYGMERVPFSSADVEFFKFQTEKSLKLLGFVAQDQLSHAKLIGGTDIFIAEPNKPNAALALAALVEGMVELGHVAVARFVARKNAAPKIIALIPHAPTPADNYYCLWGQQLPYEEDVRTYEFAPLKTKKHTPTEQQQDLADKLVERLSVREDKAREAGASFNPVLRRFFHAVEQRALDENAGIPPVPSYLESSLKMDEARQARIQDIIQGFGDAFQLKEAVKKQSERKKKSFWSDVGASAVKDEPVDDDGDQQGGGGDDDGGSEIDLDELLDGGDVTTVGSMNPIADFETLVDFGKNNKQRLVTAVTGMQTQITNFFQGGVSFYAKAVQCLAHFRKRSVEIHYASEFNDFFTQLKSTLGDESPGWKAIQKEGITLLTDQDDPTLSVTTTQSRAFLYGEEEVVLQVASATLSSQVEEMENEDDMFADFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5R1</accession>
    <name>A0A8K1C5R1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5R1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="865" mass="98163" checksum="CD073D6B0609F416" modified="2022-08-03" version="1">MATTEAVSLRVALPLSAQCFDRAVEREVVDCWLAHALEAVVGRIASTERVHWVVWTQAPHVHNVHKLFQRVIKQSDALAGQKAIVSAVLEGGVESVRSWLAEERDGVVVVYSDQVLPSTWILECPTSWVWITDVDDAVALERRLEITSQNQSRSLDALRPLHQLEEQCGWRLAMEILTQATATVRPQSTSSSFLASASIQQLPFQVLLMLLRWTYFHPRVLALVATSFTRKLARTPQQRVRNEIHTLYQQQSTLWTHSGEHDSQILQAVAVDTSTMSLSAMHIEEPPQEDEEDDVDDLTRLSQCGLWDIQKDFYRTLGIRAWSDHLIPFGVSSSSYLARQYARTAIDFLVQDKAPVPSTVVPVTPRTPNCFVWEAASGSCKFLHAFLVHFYDLVTEERLEERYGLVPCVIASDLSEQVLLSRQEMTCFQRYISDKRLDFALFDTATFLHGTNDERGSLRLRCQQIRWHLDAQDGPVFFMANYFIDSLRADVFVARRTPADSALVLKEALVDPTTRYIHDLFFCLKKTQAHPRDKPLYDDPRLNKALVQTLDRLDAAWQGARTTQSALILFPVEALELLSTLFAHSRVGILLGDASFSHRDGIPSVLLNDDNGLEIPQLSPHPDCFCLPMDLEILQTFVSLLDSRLHVAASSTPASDTFNLLYASPSSTLSTRFQRSMAQFSPSDCDLLWGMMAVEDGAKFLSNESLRRLLAQTAYDMDLFAVLMWPLYHHWKQCNLGMTDAMTQELIQTGTRCFRKVYTLQDERDSGICRLVLQLARWFYVLGAYDRVCDVLDEYPAWKKSKTLCASVTYLLALAWTRRQDASLALMNLRQSLRFAPTRQTRIKRLAMPLLKILHDQTSDKEGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C626</accession>
    <name>A0A8K1C626_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C626"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938:SF35">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938">
        <property type="entry name" value="RESPIRATORY COMPLEX I CHAPERONE (CIA84), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="55020" checksum="7B87E8FACD023391" modified="2022-08-03" version="1">MMTSALFQLPRRHAYSAADEPSLFEGEREVPEDADEAMCLEMLELVYKGEKNWRAAKDIFDQIVKKNDMRLTENIATGLIEVFASRKRPMECLETLKYAREQGVRPRIHAYSSTIACCYKEQKYAQALRVFEILRNDGYVPKQITYARALSAALKSSQHELVLEIFDDMLRNRVEPNIVTYNSILNSCARVADVHSATGVLRAIRQRGLVLSQSTYHSLAICAGKTGRWELAREVFEELKECGFSPSITMYNSVIAAYAKGKQWSEIIDVYNEMPEEMKPMLQQLYLGGVLMAFVKSSDPELQHKALEIFEEHKAKGGNDLNLFAYNAVMVYYLNTKQYEKVHALAQDVKNQGKNWDSLIYQNIILAHLHSGDVKTAETMLKKHAKHMDKSTPCYRALITYYAETKNDSLSACRLSMQMMQLNSRLSRLDWHMALEQALKLGNLALYWNFRKWMKVRAPAIVSEVPDHLMLAEDGSPRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C664</accession>
    <name>A0A8K1C664_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Thymidine kinase</fullName>
            <ecNumber evidence="2 13">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_003187</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>thymidine + ATP = dTMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 13"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C664"/>
    <dbReference type="OrthoDB" id="439028at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046104">
        <property type="term" value="P:thymidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001270">
        <property type="entry name" value="Thymidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003296">
        <property type="entry name" value="PRK04296.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="THYMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441:SF0">
        <property type="entry name" value="THYMIDINE KINASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="185" mass="20762" checksum="6FB7620F7FA40BF7" modified="2022-08-03" version="1">MRQVMGELQLIIGPMFSGKSTELVRRMRRFQHAKLKCLVVKYNLDTRYSEKNLSTHDKVFFQAKPVDRLAEVRELLDSFDVIGIDEGQFFPDLIEFCNEAANAGKVVIVAALDGTFEKKPFGSVCDLIPAAESVIKLNAVCTCCGRDAAFTRRIVSDKSVELIGGSELYEPRCRTCFVKEENDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C744</accession>
    <name>A0A8K1C744_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74987at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1517"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1563"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="716"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1152"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1616" mass="187563" checksum="26D09221C2A601CA" modified="2022-08-03" version="1">MEADASDGAVMMAASSGPPRRLQGVTQRPTELLTIPRRHLGANVSSSSSSSSESGDDENQKPKRNPVHNSLKKAAEKKFRKRYLLLQQAYEHRLQALASQVRHVVAELQIDSTIPCLQEDPLTTEYAHARIAEIIQESFFGEREKYIKIVTDQFAWQTNDLRDAEQQLRTVQRKEKAVQQKYKQTQMELQEARRQLDLHTEEAKAQYACVLQQREKIEQLTTEREQCRLQVERMQHTTESLHLLRLEYDAFKVRAQNESEQNRSIQEDLKHQLQQLREARDKADSDRKSAEQHSAHLEHLLALAEKKNDELSRSILQVHAEEFPTKLLKLEHTLEEQRRVNTTLEKENEHLKKRYEEFGEQVETYMEEQAQTRAALVKKADEQTQELRAEIGAVRQQGIDAVKAKHNELLRIADQVKFRQDALTKAEQKNAALEERVNALETMGADEKLRQAKAVSDMEKEISQLRLRLEKEQEKIKEQEARMVEVKQGYEHKIAAMQEAHDQQQHQSLKERELEARTRWQNDFVAKQEARIESLKNKYDAALEAQQNELLRARQIAIDAAKSATEKVEEVKAQHQNQREDAEEARRLREEARDAERQRAEIEKARETEHRKQLRELDEREKRLIEREQLLLKKERDRERRKAAEEAVATAAGNKKSEVTPSVVVLNMNASEDQEHEEKIAGGAIAIVNKRNAPRPLPRASENNQETDIHEDCVPRAQHKAELQAHEAQIALEAEKRVQKQMQEFQERKEREMRNAMVNVRKGIQKLEASLENEKAERKRFEEELFSERQEFVTVKSNLEEAKEAKRTMAQRLEEANNNIGRLRDLVKDALHKQMAAEERMRAAQDATARTTQDKEELQNHLDQVKKELKSCVSELKVLRAEVQTSRNASDGFAQQVEILRKQLEQQAKHFEEELAQANEDKVAEMGKLSSELWMQIRALEVQLEERSGQSEELEARSSGAQRSIEELRSYKEQLERKLEETRADQVKQRERFNDLARMYKSSSESMKAKLQEEQQKQEHLERALDDALQQRDRVKNNKRKALEACHLRVQRLEKECQELRERVASEMQAALSRFLETTRLAGAEANVFLKQALQAQNAEAHQHMEKVVNEWRVRVEEKEKELLTVLAHQKVDDQTKFDQLMTQLEHKSLLLQQADDEKAALAKRASEFEQIVKKLEHENELRALEQFHLADRLSSSQSVTEREAEEKQQLRESMARVSNTSKVLLTFVLRLMKDQRIDKTSVEAVQKRVGTGPESWDAEALQRDLSKLRQQVNDKVQTQSTQATEAEIKSLQVELDAAKAAFKSLVKAEWSASDGFSEHLPWYVAAVRAVKMEMARLAQEIEHERAAVVSREMETKGVSTSAEKLQQTIAALEFEKETLKHELNLHLQTLQKKRDQDLQDQREDYERRLEQLQRRHGKEQMKVKEEHQLTIEQLTDSLETERKKHAKLKQDTMTARVDLERLQGELEERPKKLEKEISELRDELVKWKRKAKLATKSMASLTPGTPGRHMSMLFASSFHGTDDGSSDASHHSLLPTTPRRPSTAMSDLSNLMEQSLQDLRKDNEEAQQHTPRYKLHLPKTPRSSHPSPLPIPLRIPIHPSPMRRRSSLSPRTPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7N8</accession>
    <name>A0A8K1C7N8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7N8"/>
    <dbReference type="OrthoDB" id="123702at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="51117" checksum="33B5838E64ADD7AA" modified="2022-08-03" version="1">MDALLDHLQWHEPTLLCQSAGHTWPYQGASNVVTLVNEPLEAHYTAWSDGQGDTQLLLVVGGSGTGKSRLLDEMTTVVRRVAEESAHDGLKAHGQSHVYCFHVALRNSTGCLLVPSNPEFEISCRMLYQLTKVREPWVTFSTRICVLYPRLCIEDVVTLLAKTEKLNKIQDMTVILCIDSFQRLDSNLQRVTAALCSFVSSSRAFPVVICASSTAAPIEQALASARQKHVMLFPPKLCGEQVLTPSARLGRQLVDDMDGHGRALEALDVALHRLGAGIDDIEPSIVVHEVNHQLSSCYGPLLIHEAFSDPEHCREVVAAVLSRRRFMFPTDRIGRMTVDELQSLALFRWTREGYVEAVFFAFQFVIQRIPTRNSPSHPFPEDFSRFIWCWQEFKVILALFRRVQSIAYGETTSFLRDTPIFTDPLTCFADFEAYFGPFASLAYRSLHEPPNINSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T6</accession>
    <name>A0A8K1C7T6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T6"/>
    <dbReference type="OrthoDB" id="5353095at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20556">
        <property type="entry name" value="CYCLIN_CABLES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012388">
        <property type="entry name" value="CABLES1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896">
        <property type="entry name" value="CDK5 AND ABL1 ENZYME SUBSTRATE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896:SF0">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="376"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="614" mass="69022" checksum="3E42F542520EA93E" modified="2022-08-03" version="1">MADSASPHDVASAARPSIDVDNDARPSLDTSIPEIPVENAYVEHLSEPILSTSTPSAAHQLTRSHSSSLPAPLTPIRSAPNKQVLFIKTNDSPTSHHSERTRHLHARKVTRDIAALDFLQNIPMRSEALHEAHARPHGSPKRHTDAAHAQGETSDPARDGEDSSSSDMGYMSNEALAGRRLPGFEAEVIEMPSLFRYRFTTKYPAASAVVRRWEGQTAQQGMLESRMFMSRGCGYPLAALTVLKYNGNETSSHRKRFMSVSNTEPMDYDWRGKSYYRLLHASYAPCDKDRDSQDDHPNAPAYLPNYLDDPEFRQGRHRHVVRGDKNIGPVVSSILLFVKPNELKAELNKKFQEKHTWLDSDLSLSKIRNLKRETLTTCQRLDLEVATAALACVYFEKLVLSHYVNKSNRKLYMSVCLLLAAKFNEPHASDALRLMIKKILAEIDQVHSLPSRDVLTTEFKVYAQLSFNLHVPLAEIHPHFTRLLKLIESNPRKYLDEDVFTTYSQLMLDEKTASDATARQRLLAGETPDEGTDGEVLLSDEEEIDEEEEVMVEEGGPTAGGADSRRERTAMAMAARLPWHRVHSFTQWWSDRRLSQPPTPTGTDKAEAEAPTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7U8</accession>
    <name>A0A8K1C7U8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7U8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="424" mass="48771" checksum="D589D43C785080BD" modified="2022-08-03" version="1">MTMMTEEEETLSALAFVDAFELLDESTCDLDALLDDVDTATLAYWSSERPVLEGVTTSDSNDDGNETKEEEAKPRKRRVRTPERMARLKSTVQELEDQLKALQKPRDSSGDSMWGRIAEQQKKERARAEEENARLRAILAQEVDKMSELVVKRKNLELPREFDETIKRRRNTKRIMDDHDALDKQMLAMVTSMYETVDQVLDDPRSHKPKGDRRRVSELSRDEKTGGTVLESLQNQILPFEYHSASDVVWEMMASNPHRQRVTLLDDEDPEDEDMVVQIYDRSIQLPSGLAVNRGKAVSRRFNEANRVIQATVMVTEPVQVADKPLYGVYLQTRLLHVLEPAPMATKGHPLTLKRSLVILEPVVYDPEIPKEELRQVLGMLSWFVQIKDQKILDAHNREFENRLVESLASLCINDEREEKEADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7Z5</accession>
    <name>A0A8K1C7Z5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7Z5"/>
    <dbReference type="OrthoDB" id="106293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="642" mass="73334" checksum="EE764ECE169CC4BA" modified="2022-08-03" version="1">MYRSEWPEIDTFLAIDGCESTTLSAALALVDDEDFDCFAQTPGEPISPSSSADSTNSACSASEDNEENEDTTRKSIAQPRKRRPTRRNQIQLLHATARQLEARLAILHERAANGQLASVTKARRSSRKMNQMWKHIATNQIKALSESERKNARLRAAVEDQLRLIKGLERFISKRQSKTLSWCPYYFRHSISVNPFDDPQVESEMQGCIEEMLLDVDRILADERLQGHSDEPVSVTEVTSDEQDHQVVESIQARMFPFAHQAVANAQMTMWTSEHVHMMHNVRRKDIHVDGDIVRGVLEGEFQLRDMTAVFRAKMIGRRVIQDGRIIMPAVVVIEPAMKQYKIPLDCTNQVKALNESERENAQLRSMVEDQLRVIKSLERLVTKKRSKTFSWYPEFSKSSSGVDPIEDPEFEKEMSTSIDDMLSDVDRILADERLQGDWDEPVSYVDVSSDDQDHPLIESLHTKIFPATYQAAGNMLWKMWTSTHVHAINNLRRKDVQVDGDSMRGILEGEFKARNLATHFRTKMVGRRVIQDDRIIMPAVVLIEPMIKVDDKPLSGIYLRLRICNIFRNVAGTDEPVTTRVFYALCTPMVFGEDEEHEGRGFGALTKLVLQTSRVRLNMNNQILENQLLKGFAKMNLSDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C841</accession>
    <name>A0A8K1C841_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C841"/>
    <dbReference type="OrthoDB" id="117592at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="527" mass="58839" checksum="3F27060DEDE4A582" modified="2022-08-03" version="1">MQSTPARDASRGRSLCVVGKRLARGWDRFLVELNGRFSIQRIENMREYCRQTSLLRVLLVWLSTPVPALLVIILFDCIPLASPNAGTLENYVFWIRLIPIVFILVSGPVEHFRCCLPTLPMTNFQLVLVGLAGSVPGVALGFAVSFLIGFPVPFNFVIESIAIFPAMVLALRMLWRQTLRESAALQADLRRQIFVLFGQASITYIYPLYFFAFVSMPPMAQSAFTLLLPLIKLGIKNYFSSTLQQLDDLKPAFVVFNVDVFSALYVANCLQASQSRLNTVLVCLMDITQLAVSFYDLRVVMTEIRSLVRVHQFDGSLLDLCAIASKSTGVREELDRRNSSLRTVSGKNVRGSRIVVPSSANAATSPSVVAINEALVAAGLDPNDVVQLVHKTAKILYMIEFLLLIEFAEVMIPVIYCIYMVAMSHLPNREFYPQLAALTSTELLHSITTVTLNAGLEFMSFIFVIWLVPREFKLSGPRLLAFALESHKSLVHSSLVIWTLYVILQPLTHSGVDFSLRFAWLRSKTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8S3</accession>
    <name>A0A8K1C8S3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Poli38472_010055</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8S3"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 18 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0140">cGMP</keyword>
    <keyword evidence="13" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 18 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="21">
        <location>
            <begin position="146"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="21">
        <location>
            <begin position="270"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="425"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="22">
        <location>
            <begin position="678"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="17">
        <location>
            <position position="546"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="431"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18 19">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="TMW58496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="727" mass="82300" checksum="332C3B472FEBD8EF" modified="2022-08-03" version="1">MGGGVSKAEYERIRKELLTKEQVIRTLQEQLQVTARHPSVPMNIFPAEPPASKKSNAMLAQRISYAVVPPRPTTAAFTPIPSMEATEEEKPPESTPRIKVKRRIEVSAEVMSKKKILSSANDQRVIYPKDDASKELLIKILQSNVLFTGQTPPEIRDCLDAFFPMKATAGTVVIQQGDQGDHFYAVGSGQLEILVLVAGSGTPIRYGFLGPGMGFGELALLCNMPRAATIRAVTDVELWALERHTFREILASHKMIRLNKALQVLQGVAILNRLTHHELQQVAAAMEWEEYETNTSIIRQGEVGEDFYIITQGEIRVTQVDPDAKYERQIRVMKTGDHFGEMALLKDEVRSATCTAMSHVTCLTLGREHFIAMLGTLQELMDREPGQGLTKTTSGTGFMRNASNLMLAEHASDYKYYMQIQMDELEILQTLGRGAFGRVKLVRHAENAYALKCLVKSRIVENNLKEHVLNEKRVMLSLDHPFILKLYSTYQDKKYLYLLLELALGGELFTYLRRKDRFEEPVARFYIASVVLVFQHMHAKSIAYRDLKPENILLDNEGYMKLADFGLAKLVTDRTFTLCGTPDYLAPELIFSKGHDKAVDYWALGVLIYELLVGHAPFFAQEPMQIYALIIQGDVKFPGHITRPCVDLVTKLLSQNPARRLGNMKNGIRDIINHKWFSSFPWDSLLNKTLKPPIIPQIRDAFDTSNFEDFRHETEDAGMECDWDPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8U4</accession>
    <name>A0A8K1C8U4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cation efflux protein transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010246</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8U4"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040177">
        <property type="entry name" value="SLC30A9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414">
        <property type="entry name" value="HUEL-CATION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414:SF9">
        <property type="entry name" value="PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="7">
        <location>
            <begin position="131"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="500" mass="55403" checksum="3F68D448C58C5C2E" modified="2022-08-03" version="1">MASALARLATGHSGSLALRRPRPHVQIRWWSASPPTPLVTRRLRSSGFRVSDDRLWTHSFRWLSTTTDQKDKTATTPAKPTTTTLLPTNEDEFAFLASLIADRPNPPPREDVNKAYFPGKTFRSASKDVVFRAMAGNAAITTLKTLAWLKTGSSAMLSEAIHSLVDTGNQAILVLGLHQAAGVPDKHHQYGYGRAAYFWSLISALGIFWLGAGVTVTHGIQTLMSPPEQLHLSWEIWTVLGGSFLIDGWVLKRAVKEVLATKPEGVSLFHHIRRIKDPFMMAVLLEDFSACTGVIMAACGIGASHITGNPLWDSIASISIGALLGGVAVTLIRLNQKYLLGQSVEPEIEKGIRELLLARPSIDNVYAVQSQWVGPSTFSYKAEVDFDGTYLAARLLQMYKPVFLEAKDLENDLPLILAWYAEDVTRLVEKEVQEVEEEIRRYYPEAAFIELEPDSKDTEMRAIMAMKTTSSRTSEREAMARALANLARTLDRSADRDKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8V6</accession>
    <name>A0A8K1C8V6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010168</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8V6"/>
    <dbReference type="OrthoDB" id="1602884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052818">
        <property type="entry name" value="NEDD1_Spindle_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414:SF1">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="388"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="388"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="551" mass="59702" checksum="8C009B89F1A64E8A" modified="2022-08-03" version="1">MGSEDAIVVLRLQLALWSVMVYLSCAVGSFVKTYEFSSDGVQVHRQMGALNAEVTCARYNHNGKILASCSVDGGICLDVAASGELLSRFFSPAKTPTERRLNAVNFSSGSRFLASGGNDGCVRVWDLKTQDVTQTYSVSASAVTSVAFSGYKDDFIVAGSASGAISVCDVQSTENIGFLSVDSKFDVASVTSVLASPHPYARQIVGSTYSDGSVRVWDLHTGQLTAEFASHHEAAATSLAISPVSKVLLATGGYDRRVLFFDTLQRKELRSMDFEHPVSALALCADGKTLAVGTVAGTILVYDLRGVISPLATVHAHDGGPTAINSLHFAAPTADATSAFSNTAVFPQGQPVLSTERRGSSINGMMNPPSPTNQEVMARKLQALGLSEASSPTKPESYYQQQPSTPGLTINTQIPYEPPSTQMKLEERRMSEPSLLSMLAESPRHQNRAQSTIHDSNPVALPLVSPTNEHAASPDAVFPPPTPSTTTADRNELQHQLQQLRMEMEQQWQQQQKRFDAFSQMLLTKYDTLVDENRGLRRENDTLRDYLNSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C945</accession>
    <name>A0A8K1C945_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">D-lactate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010303</name>
        <name evidence="8" type="ORF">Poli38472_014843</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000083">
        <property type="protein sequence ID" value="TMW60980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C945"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12183">
        <property type="entry name" value="LDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="25"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="136"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38422" checksum="76D73F21698DBB02" modified="2022-08-03" version="1">MAPNNQNVATTSEEGIVSTKSMRIAFYSAHSYDIESMKATAQEEGITPKHEIIFYQHRLSAKTAALAEGCEGVVIFVNDTADAATLRKLYAVGVRVLFLRCAGFDMVDLEVAKELDMPVLRVPAYSPYAVAEHAAALMMTLNRNIHRAHNRTRELNFRLGGLLGFDVHGKTIGVVGTGKIGALFARIAAGFGATVLAYDVVQNPEAVGYGAKYVTLDEIWEKSDIISLHCPLFPTTRHIVNEASINKMKKGVVIINTSRGGLIETASLVEGLKSQKIGGVGLDVFEGEGEYFYSDHSGELIPDDTLARLFTFSNVIITGHQAFFTKEALGNIAKTTMDNIKAYANKSELTNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA06</accession>
    <name>A0A8K1CA06_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA06"/>
    <dbReference type="OrthoDB" id="78780at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="115" mass="12571" checksum="3E8E6A758DB5D293" modified="2022-08-03" version="1">MADAEVVNTKDVDVEVKPNKKSQAHQDATYKVLCCGNSARDLIIIPLCLIGVYCLTAALFVLFAYSVLQTDDTNAALWVFFGIYVAFIVLLGVILGVSAYNKEQLKKNPQDANQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA35</accession>
    <name>A0A8K1CA35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA35"/>
    <dbReference type="OrthoDB" id="9992527at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF3">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="14"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="35780" checksum="BA37082398975289" modified="2022-08-03" version="1">MPSFKRYEVHTLSTDFRKATKLVEEPELPVAKPGFIVVKNHYVGINATDINLTNGWYTATPPPFGCGLDAVGVVTAVGEGVQNVKVGSAVAYRKVGAFAEYADVDAATVIPVPEANPAVLSLLVCGTSASMALDITGQMKSGETVLVTAAAGGTGQFVVQLAKLAGNHVIGTTSSDEKAEVLKQLGCDRVVNYNKEKLEDVLKTEYPNGVDLVFETVGGETLKAAVKNIALYGRVILFGFISNYADEGVQDQLRFNEVGPTLLRKSASIRGFISGNHRDQYATHFRKLMELIQQGKLRPGIDAKGFVGLEQIPEALDYMYARKNIGKIAVKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB73</accession>
    <name>A0A8K1CB73_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB73"/>
    <dbReference type="OrthoDB" id="153339at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445714" evidence="1">
        <location>
            <begin position="19"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="491" mass="51638" checksum="66836755D45BA26F" modified="2022-08-03" version="1">MVKLFATVALASLATASATPNWVGPKVGRPVDSACYRKTLRVKTCPPGYNSDKAGGCWAQCPIEYPVECGMECLPQSKDCASGALTKVNAVATAAFKTATGGIAPKLVGFDQVQAGVKCGLGLYHAVEEVSVVTQELRAQNPSMTTPQLVVELLKTEEVLSGLTSQVVSCTGLPSAVNDVARSAVKRLVEAIASKGAAVLAPDVFLALANEVGITKISEADVSKLKTLFVDGKCGYNLQSILRHVIDAVIQIKKKTPDVAQDELRAQLEQTDLFKKDIPKLTNDCASGADAGAFEKRDSIRKMLQSLIDKVIDGAYQNGNPVPVETYIVVVANLGLDALSSIDPTGLANLAKEFVQPICGPTSMVGEIDNGSADVALGLHAEGKALSNSNGTWTLAGDGQVKIFFESTDSKDVTVNVLSGGQKIGSVEVKKGGNAEWSKPLSVLQDKTLYLDRWRRGLVGIPGTGGGSLVTWIPHSSEGGHLELHAKLNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB77</accession>
    <name>A0A8K1CB77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB77"/>
    <dbReference type="OrthoDB" id="62779at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15745">
        <property type="entry name" value="FYVE_RUFY4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="331"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="337"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="78003" checksum="1772960610B3E16A" modified="2022-08-03" version="1">MGLVNLPAPMEIDGLTVYDRHTGAEKLLMSGQEISGDVLATLPKLQAAVQRHQQAGFTNGRKWKQRRRKNNVDLLELFPGGADDGYDDLDIAHALLATAELKCHVNEVLSVLIHRDSDEMDATVRSLGGRKVRDGRMLFQQQRRLSMMDADETAKTPPPTSLVGVEMLTIKPKFNVKLQTKQHLCLETCTIRYGKGERAYHLTKTLPKDAYDEIVAKEDRTALRRHLDHIAVGWDVRSLGSEGNGYGSSNHTTRVMAHSYASLVPSTQYEKSQHKRVSLNSSEMTVFRRAHMNSEAEHVMEVLTKSLREFESVIRRRRLGFQTFVSRQKEPDGYPACTICWKKFSLFRRDHFCRLCGHVVCSECSNNYDVEVRIGQVRKNRCCLACIRRVDSCNFDDEDIVPALGPYIVDSDDDAWLSTATTSYASSSEASLHSDDPREVSMALDALDQLVSLDDLMQSPHAPVSKARTKDSVRHHVHEHLSQSLRGVKGKYPAGELPVYAQERNYALEFDPDRTTHPHIPLAPIPDLAKEAKRLENIKTSGVLNPNYDRTALDLLAQVAAERMNCPVGIVSVVNETHFHPVGTYHLPPSEELPPRDENFCIHTMYAERPMILKNPQRDMRFSQMPMVRDGGIKFYAGFPVKAPDGSVVASLCTVDVVAHDHIATKEYATMQMLTQLAADLLLPPSKTQAARRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCG3</accession>
    <name>A0A8K1CCG3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCG3"/>
    <dbReference type="OrthoDB" id="69442at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="33545" checksum="30AD6E868636259C" modified="2022-08-03" version="1">MPPRPKPATPTLRRNGKRVLQALSATPVRSTLKRLLASTPQRRVLGLDINTNSTGYAVLNTHGRVCQWGHISTAHLPSSSVLDISHTISQELLKVHDSLATQPLEWHVGIEDFMRMYRFGQYHNKGIFQLAQLNGIVSYTCWQRFRARPMHTHPTAARALFGINAGKSGAKMVKNDVMKFVLEHEAASQALQVLEEHRRGGIFSDVAYDMADAYIVAQHTRWMALQEALQHDDTLLTAFGDAYLTALNPTGETKSKSKQTMEEQALEIMDARAKRSYLHSLFVTGISDWIKTQALQTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL0</accession>
    <name>A0A8K1CCL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCL0"/>
    <dbReference type="OrthoDB" id="70890at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="671"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="605"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="778" mass="91176" checksum="AA85BFDFF344D75E" modified="2022-08-03" version="1">MPHASTRAYMPEAETKMTGTALSVKDVQRCFEKERRAFLRDLESLRQQLVKKDQSAQKAAATASQHVIQLKKEIASLQAALSASEKESAKYQEQFRHTSSLLEAALDQHQADQAKLTEQNELIRNTERKHEDAVALVRKEAASNVNNTHEERKALRARVDQLRCKLEAERKEWQTIKRPMNDELDRNKMRVQLLEKELQESRYREQSSFQMKDKMNSEVTLYKRKIADLSTALQEALQNKSEMKAEHQMMVQRMKDKWRDMLHTHQHAKEQLMMLQEDYNGLFRSRQLIVEQNERICQNMRVLKARHEQAMKEKEEEYWDLEKRFKRNSATCTMCMKTPEQRQEEFEHKMEAVKEQTRLAVEKEMELGRWDRFQEVNAKYMDVCRQLQTTVHDHDMLQKDAKATRQKHEELQVKEKKLVDMLERAEKRIHEMERKYTEETTRGEGSKRQMQELMENLSNLTNVTSDQNKQLQELELARREEVESMKVAIEKVELEKERLVREQRELQEHQEQKIEEYERMKEEKAKQWNDIVAAQLSANLLIEEQAHTIDNLLKQKMTNVYVSPSKSKSSQSPTPRERETSGVSFSSDEQSTNSKEPGPLESATIAVLRRECENLREELVTVRASSRQDKDSLQNEYEQKIVDLMREITGLQRERGKLKRRLEEQAVTIHELTVQEEEDSECDDEEDGGQDEPLVHPQGTVETRDPVYQRRRSRSGEPVPRNRGSVRAGWAPTPTRTPSRRLSARVPSVSFKNMSQELSAIQPESDDDTVGLSFLSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCS8</accession>
    <name>A0A8K1CCS8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">D-lactate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010302</name>
        <name evidence="8" type="ORF">Poli38472_014844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000083">
        <property type="protein sequence ID" value="TMW60981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCS8"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12183">
        <property type="entry name" value="LDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="4"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="115"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36198" checksum="7E81A45C0403B5ED" modified="2022-08-03" version="1">MKIAFFSTHSYDIESMNNTGKAEGVLPEHQFEYFTTRLNAQTATLAEGCEAVVIFVNDTADAAALRKLHAGGTRLLLLRCAGFDMVDLEVAKELDMPVLRVPAYSPYAVAEHAAALMMTLNRNIHRAYNRTRELNFRLGGLLGFDVHGKTIGVVGTGKIGALFARIAAGFGATVLAYDVVQNPEAVGYGAKYVTLDEIWEKSDIISLHCPLFPTTRHIVNEASINKMKKGVVIINTSRGGLIETASLVEGLKSQKIGGVGLDVFEGEGEYFYSDHSGELIPDDTLARLFTFSNVIITGHQAFFTKEALGNIAKTTMDNIKAYVNKSELTNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCY2</accession>
    <name>A0A8K1CCY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_013567</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCY2"/>
    <dbReference type="OrthoDB" id="10264771at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW61104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="28255" checksum="1BAB19174513B59F" modified="2022-08-03" version="1">MASKNPRILALFDIDGPLTRARQSAKPEVLQRLKKLRESISVGVVGGSDLVKQKEQLGETVTDDLDYSFSENGLVAYRDGVKIGETSLRSHFTNEQINRIVNFALRYIADLDIPVKRGTFVEFRTGMMNICPIGRNCSQEERDEFGKYDHIHNIRKTFVAKLKEEFAEYNLTYSIGGQISFDVFPSGWDKTFCLRYLDPKDYDEIHFFGDKVHEGGNDFEIYTHERTIGHAVTCPEDTVKLLDELFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD36</accession>
    <name>A0A8K1CD36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sucrose transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD36"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000356">
        <property type="entry name" value="Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="52256" checksum="D6EE1D2CBDF2AF43" modified="2022-08-03" version="1">MSTKDIEAGALTPGYEQFGSPKVDGVQDGEPRRGVSLGMLLLISMPRMVIQMAWSAQWAALGPYLGTMLPRFAVQLTQVIGPLSGILVAPTIGVLSDRSLNKWGRRRPFILYAGIASVICWILMGFTRQIGEACGDYGNGSPGVPTSRTWTAFFMVIFYTWMDVTVNVVQVPVFLMISDLAGDRQTTGAALGQGWSTLGSILISGYIEIFGPAHQSLGYFLGMLAVIMLVSVTLVCVFVKEEPLQETDAPKESTLKQIGQAFMSIYTGLKSLPAVLAIYSFIFFCVMYGYTAYNGNKGQFFGIEVYGGIPEGADQCSESAAGCTEEQDAFNHGVRVAGGSTDLIFNSVGYVYSWMVPFLVHKIGAKWTLTLSLIPQALLAVMAFSDIVGLDVFIVVVTSLSQVIVFALLVPVIVHVYGDKEDIGVYVGALNSANCFGQLLNFIIGAAVVETSLGYKLPVFIGGIMSIIGILVSIFFFKIKMYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD80</accession>
    <name>A0A8K1CD80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD80"/>
    <dbReference type="OrthoDB" id="156610at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010402">
        <property type="entry name" value="CCT_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06203">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51017">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCT" evidence="4">
        <location>
            <begin position="254"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="300" mass="33438" checksum="F43164C73CE7F2C6" modified="2022-08-03" version="1">MLTERDATTWLHETNWSDDLNALSLDKSLFNGGSADGVLDKVNDDKLARDVEDLSAIFEELEDGVVDFPLPCDDQEVATGAEVTGDWIGDLEKDVVNVEELSAVFDALASEQASALEQAESSEEFYSEDDDEEMYSDDEEEDDVHDSRIPRIPARIVPAPPTWAMSAPMDPRSAIRTPVFKNLDSRIPRVEIPRMDLAFGSPAKKATPSAGVVPAARPTELASPKACKDKKIASGYKHDPASCWICKSDKTPFRKFALHRYLEKRHRRNWKRGPRYSGRSNVATGRVREGGRFVCTAHWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE67</accession>
    <name>A0A8K1CE67_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE67"/>
    <dbReference type="OrthoDB" id="78236at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052384">
        <property type="entry name" value="TMTC_O-mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="621"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="680" mass="76664" checksum="CAA759654DC0FD9B" modified="2022-08-03" version="1">MSSLSALRDALTALGISTSTGDLRGEARRAALQQRLEAAQQGHSTSAFVAFKAPTPSAPENGTAQSTASFQHLSLTELRTLLEQRQLSTHTPGLKGDARRHALIQRLVNEIQTDRSVVSEPIEDDLPSLSARSTASTSSSTYSSAGEFLYFDLPSAFSSAKVQDPKSKASPSIPALRLSAKESQPSTETLSSDPTRQQFEYELIELRKELHTRRARRCELLTHRMEANGFSTSLESLSESMARLEKERQRLERSYYGRELVTTSIITEQPSEFVQADVIQWISKRQDQLRRQIHHTKDALAIMTPESNQTEEGIIDEKELLSRIQQLEAELCVSIRSSSSSWRSMSSPTPSNETPVLVRCQSLPANRFHETWQALDTPQRQQLHAELRSAASFRIQSGRVALHDGNTHNQTARTAAMPLFTQYPPTRADKLGIKARFLEQAARSVLEVNRTYKQALAVDGDHVANLTYYASFLYRRCEQPEQAESMLKRAHRLAPNSVLVLTTYAHFLHHKRQDIAKAEAFYQQAMKQTPQGPVVLGDYATLLCERAQKEEFNEKTLRQAKQLLQDVIRMAPSDLFVRLTLAGVLNQLKETQAAMKSYETLVRGLQQRKHQPCPAEKALMARICCEFARFLSDQGQYDRAKQHYQLALSTTPQDSSIARQFSLFLRDRRHLLTPTSRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE87</accession>
    <name>A0A8K1CE87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE87"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF511">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="55"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="116"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="22049" checksum="8ABB0FC10A79493C" modified="2022-08-03" version="1">MDPNDDQVVEETERSTSPTSHSMASVHANEAARASPFRKFRSLLIAKRYEGHDDLPIQVIPGLYIGSFGAANHLQGLQDAGITHILCVTPTLPFVFPEQFQYRRVSVGDTPDVAIDTFFPSSIAFIDSALAAGGRVLVHCQVGRSRSATIVLAYLIQRHHQSFQDALALVRAVRPQIQPNQGFLRQLRRWAAQLTSTASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF35</accession>
    <name>A0A8K1CF35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009764</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF35"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000002">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01228">
        <property type="entry name" value="Met_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008900">
        <property type="entry name" value="PRK12267.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF2">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="15">
        <location>
            <begin position="589"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="752" mass="85269" checksum="99170F1A56FEA00E" modified="2022-08-03" version="1">MLVVVADKSTEELSLITTQVTMASELESKISQLEAEAELKDARIRDLQQQVKKAVDDNAKHREKFYLSTAIHYTNGMPHMGHAYENVTADVITRYHRTFGREVFFLTGTDEHGQKIAQTAEAQGMAPMELCTKYAAIFQQLTKDLNMANDRFIRTTDDHHKKFAQWIFQRAIDNGDIYLGTYEGWYNVREEMFVTETEAQQTDYKDPATGTPFKKMQEKSYFFKMSKYQQRLVQHYHDHPEFLQPEVRRQEILRRLEEPLQDLSASRTTFSHGIPLPNDPEHVLYVWFDALSNYLSGIDYPDGENAKFWPANVHLIGKDITWFHCVIWPCILMSAGIPLFKRVYAHGFINAKDGTKMSKSIGNVVDPYDMINKYGLDSFRYFLVRSARFGQDMPFSEDDLINIHNAELADTLGNLVHRTVNICKKYANGLVPDARADTPFDIYTLLHESEIAYKEYALQNACFVVLNALRETNKYLTDKAPWHMKEDAPRLVVVRTCLEAIYVAAHYLSPFMPETAQKIFEKLGTAPMLLTQLSPDYDNLKVGTEVTIGDILFNKVLSDEEIKKQEEAAKAKADPKPKAVKAEKPATPLFASLDIRVGVITKVWEHPDSEKLYCEEIDVGEDEPKQIGSGLRPFYSLEEMQGRKVLVLLNLKPAKLGGFKSHGMVLCASNEAHDRVEFIEPPGDAQAGERVFIDTESGEPLSAAQLKKQKVWEKAAVDLVTDAEGVATFKGQVIKTAAGPCRAKSLTNVHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGG7</accession>
    <name>A0A8K1CGG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_005535</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGG7"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000004">
        <property type="entry name" value="Histone acetyltransferase KAT2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="204"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="442"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="59166" checksum="99AF925D36B31F0B" modified="2022-08-03" version="1">MAETDGDVAMTAPVEATEVEMTTAPAPAQEETTEMVDVPSSEANREETTTNDAVKDIENVEDETAKHGDVAVSTEEEAKEVEATVQAVENDQQSSEDVDMEATTAPESAPTNGETATPQSEVKTESEDGAALKRKEPSEASTKEVADVSNAADASAVARQPAKKQKVDETPASTGPVLASAPIMISRDDMAKMEEDGGMLKFDVITNDGTPERMIQLTTLKNIFARQLPKMPREYIVRLVFDRNHRSMVILKNGKHVIGGICYRPFEPNHFAEIAFCAINAADQVKGYGTRLMNHLKEYVKSTGITHFLTYADNYAIGYFKKQGFAKVVSMPKSNWFGYIKDYDGGTLMECTIHHQINYLRITSMVQQQRKKIQDKIKERSHADIVYPGITQFAEGRTMDIYMIPGVKEAGWSQAVIRNSRVGTRDPGSLRTQLQQLWKAMSSHRSAWPFHEPVDTAVVVDYLDYIKEPVDLSLIQKRIESGHYLSKAEFKNDLDKMCANCMVYNTPDTNYYKAAKDLQDFIDRRVQLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGP8</accession>
    <name>A0A8K1CGP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGP8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="59714" checksum="5EAEB87ACA5BF716" modified="2022-08-03" version="1">MVLQALFQQGRLALQELDTTQLAVGLLVSFVLYKALLKRDRGSGKYKKPYRPKATLPFFQNTLAAVTRADDNHDWMLELCKESGGKPVLVKLLGQPPIVIISDPELVEDVQKTQFEIFPKGEMQCEILGSVIGEGIIAVDGAKWVHQRKTASHLFTTRSLRDSMTATMRKYTTVLLRILDRARADGKSIDMFKLMNRFTMEAFSEIGFGIEMNCLEAEEEHPFQSAFDSAQRTIILRFLLPGFVWKLQSFLGIGAEGQFKKDMKVIDDTVLDIIAKSFQRRQESGAKENRVDLVSLFLDHFETSPDNQGKEFDPRYLRDIVVTFLIAGRDTTAQALSWFFVNLTKHPHVAEKIRDELKNVLPELYEGKIDSPSMEQAHQLTYLEAALKESMRIRPSIPMTIKSAAEDAVLCDGTFIEKGSRVSMPIFAMGRMTQLWGPDADEFNPERWIDPTTGKLIQVSPYKYLAFNAGPRTCMGMNLALLEMKIVAASVMSRFEIEVVKPNEVTYDFSVTFPIRGELQVNVTNVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHF4</accession>
    <name>A0A8K1CHF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Trifunctional enzyme subunit beta, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005464</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHF4"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000011">
        <property type="entry name" value="3-ketoacyl-CoA thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF153">
        <property type="entry name" value="TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="303"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="7">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="47952" checksum="12B36A599E90FE09" modified="2022-08-03" version="1">MLHARRSLLQNTRAFSAKAAAKERRVVVVDGVRLPFAKSGTVYKDVMAYDMLRDAFKGLLVKAALDPSKVDYVYGGTVIQEVRTANIAREAALGAGIPKNVPAHTVTQACISSSQAICNGAEKILAGRADVVVAGGVETFSDVPIRFSRPVRQRLIGLAKAMKGGPLGVLKLLSGLKLSDLAPEAPAIQNFHTKEIMGQSSDRLATRFGVTRKEMDEYTIDAHQKAAKAHAEGKYKGEIIPYKGQTTENGINTESTYEKIAKLKPAFIKPHGTHTAANSSFLTDGAAATLIMSEEKALELGYKPKSILKDWEFVGVDPFEDLLLGPAFGIQKVLAKNNLKLEDIDHFEIHEAFAGQVLANLNALSQPEFCKEQFGLDKPVGKVDRSKLNTWGGSLTLGHPFGATGSRLVNTASNKLQKEGGKYALLAACADSGLAYVGLIEKYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIB6</accession>
    <name>A0A8K1CIB6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIB6"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="33"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="181"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="34950" checksum="CB9A626AEE0E108A" modified="2022-08-03" version="1">MKQTEARPLLPTQSLQETRNADSFFGIPRRIQGLLLVALSGFTFSLLSAVVKYTSYSMPSMETAFWRSAVACLLNLVAMQAYGVSTRVERQFWAPLAIRCVGGCCGVVFGFYAMQQLVLADASVLLLTSSVMTFFLGVLVLNERVDAINLGSAFFSFIGVICVCRPPIIFGSASDDHPPLLGVLSAFLAAAGEASGYVSMRRLQELHFTVTIHNFLVMCTVVSSLWLAATRNTIVLDLSVSLWCAVLALGVLGFLGQLFLTRGYQLENAGPASIMRYLDIVFVFIWDTVFLHETISAWSVVGAVIICTSAIVLVLHRLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIC6</accession>
    <name>A0A8K1CIC6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIC6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="22531" checksum="613621934FE6CEFD" modified="2022-08-03" version="1">MQHEILEEHSLQSSVDEHQDQPHPDVSNLTKQHPLTPSELDRHQEFVRGDIPAYEAKIEFANAHGRPKHPVWQYFSHAHLQQHTKQLPRLKHSTTDHVEVTCNFCHMKLVREETMTKGSNEALVQIQLTRAVLHDMLNHLSSCTMCPSHVRLEMKSWPSVPRSFGGKHETPHAIEHERLHDPLITIPDINPEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIK0</accession>
    <name>A0A8K1CIK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIK0"/>
    <dbReference type="OrthoDB" id="21557at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051078">
        <property type="entry name" value="SGF11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367:SF1">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="99" mass="11012" checksum="AECEAE3670192E37" modified="2022-08-03" version="1">MDDQLLAFLVDDLIVDLCFEIHQQIKTVGMTLEELYEVDPLEKVDHAPIVPQSLVVSCSKCKRQVHASRYAPHLEKCLAGTRRQSTLARASTDDTASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIQ6</accession>
    <name>A0A8K1CIQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIQ6"/>
    <dbReference type="OrthoDB" id="2438421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052717">
        <property type="entry name" value="Vacuolar_transposase_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46169">
        <property type="entry name" value="DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46169:SF29">
        <property type="entry name" value="DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140996">
        <property type="entry name" value="Hermes dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="2">
        <location>
            <begin position="781"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="904" mass="99521" checksum="E97744C914CFB358" modified="2022-08-03" version="1">MAPSPANANHDTPLTLEELENSTRNGKKKLYWTAFEVVLATTSTDASNGAPATLETRYDAYQVNHNQLKKLHGQSARSVRVECKYCRSPRFTQSITVSTKKFEEHYMTLHALDALASANAAKAMSGKTSTGSATEPDATTRAKRGRPSSAPTTASTPKRTRTRGRGSEEDEQVSMDRAEAAAAAVVALSAGPSASGAQQSLGDEPVLLHSADSDTKRVKKSYWTAYDVVITETVVDPETQARDVKVTRHDAWKVNHSALRRLHLESTNDTSVRVECRLCASPKFSQSITVSTKKFEHHLQDDHGETRHLQDEDDKSAVSLTASTGVTTTMNGGSQPPRRRRPWRKLLQEHAEASMGFAGQSTKQPTARVQRASEALFQWVVQDQQAASVVESEAFRVFAQTLDRRYVVPTKETLKNELHERFTAIKREIHGLIHANAVSGTKCTLSLDQDASFVSVTAHFVSPQWRSQRLLLACRPVVSNMDSEEHERVLRDVMEEFGLTDSVLAVVTSLKDAKWTDLSLPHVVCAAQTLERVVTAGLASVSDLLTRARRYVLRVNQDDVSDDDESELPMDTPSQWLTTVEMLTAVLAHSKRHTTSGLSTQDQTLLFSLTRALAPAARVTHDLITTEYPSIPMVFQLMRFLHDALEAGSDPIQTLMLIELQNARKTMLPSEALMAYALDPRFRLLQLSPAEQRRVRSAFATALEEDSSTTTTTTESTASKDKPANDKPEEDDGEDTEDEDEPLPSTRRTTSLFEELSSASSATKGKTNTTVAAAKTSTLTELDKYLAMENEAFDVDVLAWWRAHTTEFPHLSRVARQWLSLVGTSVPASALLTSEGQRQRVMRSLLPSDTLEATRVLQAFDEDTRWVTNGAEASPRDATSNTTTAVKPSEGASTRSGAIDDIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJD6</accession>
    <name>A0A8K1CJD6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJD6"/>
    <dbReference type="OrthoDB" id="156520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="512" mass="57021" checksum="DE84E523D2B14580" modified="2022-08-03" version="1">MRGAALRIAAATRNSSTRAVDHHVRHIANANVRLPSASVASKTLRHVRGMTALRCFSTQVDLVAGREALKKAERYIEEDDLANAMKYLNIAAHHDVADAQYLLGSLLEKDDEEDEPEDEQELVADAETNRQLVNDPDEPQDLKTIRKRARKHYKEYLLSKRANGEDVPVTGRLSRSIVQRATTQELDRAFGVTLQQLLDPASTLRPLSAVVDEEVTEAEALGGDSTQSIEWLRRAAANGHRDAHVYLGNLCMEQEPPLVNHALEWYFNVTPPKVEKDPHPDALFNIGMILYEGAEHANPPFPANRAAAIPYFVSAAEAGDTSAQYFMGQLLLGGDDELEIASDPKSGLMLIERAAENDHGGALFYLAQLYRLGDEECGIKADRHQFLNYLDLAMEAGDEDALYCMADIYYHGSDGFDKDLEQARLFYLAAAEAGSAEAFCCLGAIYYNGIGVKKDYQKAFLYYQEAAERDSMEAWKNLADMHYTGRGVPKNEATAQSILKMLQKMEQEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJG5</accession>
    <name>A0A8K1CJG5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJG5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="15807" checksum="91330AEF9B901288" modified="2022-08-03" version="1">MRKRKFEEDYEDDYVEWMDRHLASLKEWEFVNLKVGARDGVWTGDDVRELLVSSWENYAAGAIDYAPDDMMDRLDTDGLGLRKAQEVVWVAPPRKFPFEKVGAAYGNEPSVENYYASACLIAWVPPSSERMSTEKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJH6</accession>
    <name>A0A8K1CJH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013012</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJH6"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055361">
        <property type="entry name" value="tRNA_methyltr_TrmB_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF21">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="26292" checksum="3DE19779895C429E" modified="2022-08-03" version="1">MASDADVEIRSVTAKRVRQHVNPLSQRYREPIALPDWTACFAQPELPIHLDIGCARGKYLNAVAAEADGRMNFVGVEIRQSVLDEAKEEAELRKLRNIAFIHANMNFQQSLLIPSLPGPIQSVSIFHPDPWMKKRHIKRRLVTDEFAQELADLLADRTPIFVQTDVQELFEYMVEIFEASGRYDFEPMPTNPFGIPTDREKFVTNQGGDIYRIKLFVNHKVKVEESPGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJR8</accession>
    <name>A0A8K1CJR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta'-coat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJR8"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="137"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="183"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="33930" checksum="1A8524EE1745731A" modified="2022-08-03" version="1">MTRFSVSQLLSTPSARVKGLDVHPERPWLLMALHDGSVVVWDYSANQLIKIFSVSASPVRSARFIARENWVAACTDDHRIRVFHLEANAEVASFVAHGDYVRDLAVHPTRPLLLSASDDRTIKSWDRSENWSCTRVFKGHGHYVMSIALRPGSSDTNVAFVSGSLDHTARLWSLDSDEALGILRGHTKGINAVAFNVSGSHVVTTSDDTTAKLWDVVTHNPVATLTGHTDNVTSAAFHPTLPLLVTGSEDQTVRLWNTETQQTETVWTQGLGRAWAVRFLVDKPTAVAIGYDNGVQVVQVVQVDEASNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK62</accession>
    <name>A0A8K1CK62_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK62"/>
    <dbReference type="OrthoDB" id="75966at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="766" mass="84696" checksum="263E97902FC6232E" modified="2022-08-03" version="1">MEQLFERDVSAYFHCQDATLTAVKQCRCRWCGQRVRLQEDEMLQHVATQCSRERTPVKAVLVSTERLATPPAIEPTPLRQIRRLHGARASPLTPRSLLRRQPLRAIAHDKENAHPSPLSTRYRRSTEAKPKRPLSLEFQGDMEPLKKKQVIKTPRVTSQATQTPTQTSESKPKASEDTVAALLQDLTIACMVENVPLGFLSSDSFQHAMKKHTGVALPRDASSQAMRFLRRERIQADAVNTEICEHDGALTLVVTSTVAVVGTSMHSYMSFYVVNEERAHSLLSTVALKPEDDWMAVIQTKYEELRSSKPQAAVHLCLSAYPTLVLQRVAKTLFKASPSSSLPSLVGGCMAIEGMWLLNDVMAMLTDAPQTISMAAKIAAAANAVDNQVDSGVVVSLPQQRPHFCVQAVWILLSQLVQRASYLQSRWGREEVVESGDSPWRQPVTKLQKLLNEASGKALWSKWAALAELLAPFAALEALTSMPRASNDNQADPSPVLTSGVLMSLEVAAFQRITTSPLLSADQREKWQTSYLQLLRSRRHDHHVAALLLDPRLRGTGLSALGRHAALNCVLRLVRRVNGNVDEQQVGSQISDFLNQRGVFDDAALWCSTMMANPMTFWRSVKPQDPFTQVAALVCGYAPFTPPSFDSLKPLADGEDEVVLTAAGRLKHTFVNRDMSTLPLSARVLRNMTPSSTEDDFDDVEQAEEADVGMYSARLKALLRRMGQLRSASGEDSTTPTSMGFQGDWIDLTALGRHSVDDILAQLHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKZ5</accession>
    <name>A0A8K1CKZ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKZ5"/>
    <dbReference type="OrthoDB" id="123206at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57384" checksum="203EEA9F3763252B" modified="2022-08-03" version="1">MRLGAITESLPEMESKPKLEVDDARRYGNMTGMTETGDRTWRTSTGKRSTRDQQPDAASSPSISYASDAVAGLDLSSVSSLCHELIAKKRMMLNAVTLASPTSEMDGSRDGVKGSDDEPGDHSDNGMRSVKLPTAPLSEEDMIKRKAQRRREQVRAASRRCRDRQRRETEELRMKVFKLEEFIAHTLQTYESELRRQQLQIEGLQQENESLRYRLGMSASPSAPPTVIPSVPSPPVAPAPAPVAPVVHQPYESPIKSAPISDEANTLSDDIRRIKWDAARIQNVHSTVNLATRALVSIRNTITPVPEVSRQAFGWQFEMWDDGALFYAKTEKFFRGVRAYDVAQRFFNVDYGKYMETFHEVKDKKVLKQLGPNIKIVQTVKQHPGKELSASVTCNFIARDEQFAGERWVTGIVSVGSAQHLFFTHEDECNGYMYEDVTRVMSDGREVRGCVAYGLGRYQSNGMDLKLLVEELAKATASVVLRWESLFINDYMIDEEEHLGDIESLSFADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL00</accession>
    <name>A0A8K1CL00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012905</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL00"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="57591" checksum="F993057EC0AC868C" modified="2022-08-03" version="1">MAATATIARPNAGETLRGKQKEKDVRMSNIIAAKAIANAIRTSLGPRGMDKMIQQGNGEVIISNDGATILSQMQVYHPTAKMLVDLSKSQDIEAGDGTTSVCVIAGALLGACEDLLLKGIHPTNISDSFGLAARKAEEILTAIAKPVELANREELINCVNTSLSSKVISEYSDRLSPIAVDAVLKVIDIATATNVDLNTIRVVKQLGGTIDDSELVQGLVFNKGFDKAATANLPSTIENAKIALLQFCLSAPKADMESNVVINDYAAMDRILREERKYILDLCKRIKKSGANVLLIQKSILRDATNDLSLHFLAKMGIRVITDVERNDIEHIATTLGCLPVANIEYLTPEKLGTAGLVQEETLGGHKVVKITEIVNPGKTMSILVRGSNKLVLEEADRSLHDALCVVRSLVKKRFLICGGGAPEIHVSQKLGEYARTLVGQASYCVQAFADALEVIPYTLAENAGLHPIGIVTELRAKHAQGQANQGINVRKGSISDMYELNVLQPLLVNLSEMSLATECVRMILKIDDIVMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLI4</accession>
    <name>A0A8K1CLI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA-processing protein EFG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">rRNA-processing protein efg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009068</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLI4"/>
    <dbReference type="OrthoDB" id="47732at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019310">
        <property type="entry name" value="Efg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050786">
        <property type="entry name" value="EFG1_rRNA-proc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10153">
        <property type="entry name" value="Efg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="221"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="283" mass="32813" checksum="FEA78E4A323FC3E8" modified="2022-08-03" version="1">MGRKWMCATLNYLPANHHHGALDEKQLAIMPPTAGTRLRFKKVLSKKPFKKQKKVPSLKNRIRALERFLKRDNIDAETKSAKEKELDQLHQERDGKVQVEEEKKIAEKYKKPRFFERVKLMRKLKQAQSHMEKASDAKEKRKYEKEYEKHRQDLIYIYYFPKAEPYISLFPAKPLSENVLKRQAELRAAATKQFDEEQPLDAFHKFCYADGHAANSGAAALLAKKPTKEEEKKKKKPRNKKDKTEGGATSSKKSRVVADEDEVSDAEMAEGAGDEEEDDDFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLI8</accession>
    <name>A0A8K1CLI8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLI8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="15957" checksum="12B920D04D981903" modified="2022-08-03" version="1">MTSTLSKGDNGFVTFTFILSGSGATTDDHSAKFPSVEGASIVANITNVENAKNAKVTFTQCNPGTTDAETRVRQLGATNSTTPEVGKLFVIDSNCLTVEVSAPNSKNGRLDIEAALIGDFCKRSPSADVCEKYDPGVVMPADTKWRSSKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMH2</accession>
    <name>A0A8K1CMH2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004116</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMH2"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000056">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW66351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="32960" checksum="64DCA13732405E42" modified="2022-08-03" version="1">MSGRGMRGGRGGGRGGGRGGAGGRGGGRGGGFGGRGGAGGRGGGRGGGRGGFGGRGGGRGGGRGGRGGGAPGMKGGAKVIVEPHRHAGVFIARGKEDALVTLNSTPGKSVYGEKRISVDVPSASGEGTEKVEYRVWNPFRSKIAAAILGGVDNIWIAPGSKVLYLGGASGTTVSHVSDIVGPTGAVYAVEFSHRSGRDLINMAKSRTNVIPIIEDARHPLKYRMLVPMVDTVFADVAQPDQARIVALNASYFLKNGGHFVISIKASCIDSTATPEAVFAREVKKLQQEQFKPAEQLTLEPYERDHAVVVGSYRAPKKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMP1</accession>
    <name>A0A8K1CMP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMP1"/>
    <dbReference type="OrthoDB" id="97450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471427" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="63"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="194" mass="21566" checksum="420BA6623E21EBBE" modified="2022-08-03" version="1">MKLLAALFLSLVCVGYASDVPQEESSEALPLPLLEFYSPDWNQTQLQEEAGAVGDANSQKALLDRINFERARRGLRTVCLNSKLTKAAQLHTDDMARSGIMSHSGTDGSTPKMRILRQKFQYSKYGETVAAGQTSVTSVMNAWMNSKGHHDIIMDPLHRFVGPGYAYSSKRTDLFRHYWTLDFGNSGSEACDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN50</accession>
    <name>A0A8K1CN50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Katanin p60 ATPase-containing subunit A1</fullName>
            <shortName evidence="7">Katanin p60 subunit A1</shortName>
            <ecNumber evidence="7">5.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">p60 katanin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">KATNA1</name>
        <name evidence="10" type="ORF">Poli38472_004150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN50"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21748">
        <property type="entry name" value="Kp60-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03023">
        <property type="entry name" value="Katanin_p60_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028596">
        <property type="entry name" value="KATNA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048611">
        <property type="entry name" value="KATNA1_MIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF19">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21126">
        <property type="entry name" value="KATNA1_MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="317"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="325"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="577" mass="64340" checksum="83C2F406C69B9CBF" modified="2022-08-03" version="1">MQLHDIRDMGESLTRARELCQEAQYDKGMGMYQQTLARLRQFIRSMTKMTERQPWLQMQIELENELSLITDYMELIQAFKIPPGMAKHSPPAKNHHYRPPGPVDEPAPAPGWEVYTPESRKQMGEDRDPDVWAPPSPDQYGRGGNKGGFPAARAPPPWANNDHGNNNNNRVNNRVVKPSAKPSAARAAPSSDRPSGRRTPSDDQRKARPALDNRKNVGGNAAKATGSNGKPVKKDADKSKAPSGGNGEKQKYADLAREEGWVDLELIEMIERDIVDSAAKIMFENIAGLEHTKQLLQEAVMLPQIAPHLFKDGHLKPCSGVLMFGPPGTGKTLLAKAVANVCNTTFFNVSASTLASKYRGESEKMVRILFDMARYYSPSIIFMDEIDAIAGARGGSQEHESSRRVKTELLVQMNGVASGDPSDPSNRVMVLAATNLPWELDEAMRRRLTKRVYIPLPAPEGRHQLFKLNLAKVDVESDVDFDKLVAETDGYSGDDICGLCETAKMMPVKRLYTPEVLRELHRKKQEGATEEELKAHEKNALVVTWQDFKTALENVSKSVGQDQLERFVKWEEEFGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNA5</accession>
    <name>A0A8K1CNA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008398</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNA5"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="637" mass="70476" checksum="AD7C7F611FC7E731" modified="2022-08-03" version="1">MGKSPGLKLQAAVVQDNVPVEVAPRVFVGSIHAAFNIEALQEKHITHIINLAGNYATFPESFTYLSISIRDKDYSNLLSCLPMALMFVDAGISSGTGVLIHCAGGRSRSPAIAMAYLMIKDQVTFEKAYTHMRTIRPVVSLNTGFEAQLRCLDDAHGDVFTAHQLVLQYRLATMVQQRADGFLDMELLKKKRRHRHHQPHYPSHQAERTESYVEEALHSRAGKSPHRGSHEYHTTPTFCDERGMLHGRVPSGFNLSTPLDLKASPHFIPALRCMGTMFGCSACGENLFNASSILTHAKSKEGVCVAKDTEKHEGIDEKASRSESGPQPRTELTSAPSSKAKRPLLAKLRLRPRSPGLVNDKVLSPETKRHSDPPAPTTPVLKHPKKDKDKEKVVSPTHQTKPAASESKPKEEKHGHEGFWRTLTNFRSSKRNIKDAVAGRSGNEDQKKKQMTLSPKSIDLSPREDPHLQFLRENAQQWERKVKEFEHATDQTVAETSSSDVANQLSMLMAHDAQRMSMLDCDAWFIEPQEWFTQDMGEASHGTIVCPNERCGGELGAWHWGGLNCSCGGTVAPAFQLQKSALRVLGNVTIPPEQLLEPPMPAHSSSSSSSIFNLVSPAMTPRHTSRPAIERLVCASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNS6</accession>
    <name>A0A8K1CNS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein phosphatase 1 regulatory subunit 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1571"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1583"/>
            <end position="1606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1698" mass="187643" checksum="2510F23DA5E469EA" modified="2022-08-03" version="1">MTRNEDATPSTGSNPESIAPVKPSSAPVSRSSHESELSSDGPHTNGETSMQQRERVQLFETSADLQELCRDNGITSSQFAKRAQFVTSLDMFLGFWPSMLTVMYFPALRELSITKHPTIAKMEGLTSCLNLETLSITECELERIEGLENCKKLRRLNLSSNLIRKMGQLEFLPELETLWLNDNRIEVLEGLGNARKLTTLWVARNQIERIDSALNGCTSLTELNIADNRVSSFKSLLGLANLDQLAVLTLSDPHFGDNPVCRLCNYQTYLMCQLGRLYWLDTFELSTRNKQIAEATMVKKKMYYNMRIKTIKRQVQLRIRHAEVVRSHTAQHLEGNIEALLTHKKEIEKFLLDTAASPESSSHASNFADKLQRIEACLQKKSAAIFRMNQEFETLRARMQRTGDTSVSRLLLELETGGNIRLEDGKPTDPWYSSCVDLVRSRLFPADLRAFGISDVQVNRVTRINNRHLRNRFHTRMEEILVVNEETVKDNVSKKGVTVPVKEDNELDESNTGVKYTSTSASSPENSLEYLFYVQPPVFHFMRNAEYEHCFAAENGFRDAEAYRNMGLDGAVKLSNSLALSDTSRLLAVIAESAVKEHRRDRILQEALRFSCLSVTQQEKEMRTGLTREMRDVIQQAARGGWEIPPETLLVVKVFPGYTKTVSASEEIPLPIHGQQYPGVHSLQVIKSTSTPGVPEPASPTQKMYYMFDKMLILPEYIVEYEYVSTAKATAAAEAALDPQANPKLQLSQDSGGDLGPVGRLAEEFERRYRTRRPPSPQVIDERGDSLLNTTVALDENVAQLIRGEPLSVVHTASIDSTLAKAKKNLQVGHIKCLDLLGCGLEAIPDLTSARNSLEVLVLSNNRLSELSSTLTGLVRLTHLDLSGNMLRHLEYLETLGSLTSLDVARNQIASFDSVVYLSRACKSSLRRLDLRKNRIVDSKRYRLHVLHNLSALSTLDLQVVGREEVIMAQQLLTSLSAQSLWDHFRSSNLLTTTTNDQSSATMAPTAAFNWSTVDELTLNRELITSIEGLDDLVNLRSASFADNAILKIAGLPKCTRLEDLSLEDNEISRIESLEALVLLKRLHLGRNRIVCIEQLDRLENLIQLSLEDNHITSLRGLGAALKLMELYIGNNRIDVLKEVQHLKSLPKLTILDLSGNEITRLPDYRLYTVYCLRRVKVLDGVSISPQDQSDAKQKYSGKLTLEFIMEKCGGATVDRIQDLDLSSCRIRELGAVNGRLFASLRELNLESNQIHDLSGLEALPKLRVLNLNRNRIEKLLPQGVTTATAFLSPEAVEAAKGILSCPKLEQLYLAYNQISDISALGLHALDELKVLHLQGNLIASLSGLDINTELVELRLDKNKIRQLDLLAATALRKLRVLSLDDNGLKSLSGLSEFTSLEFLDVSTNRLAELEEFDKLAPLTTLTELRALNNPLAKKYLYRQTALFKLPTLKNFDGREVASEERDRVDALFLHERATATLTGERTGGQLNLAPSSIPGGGKHGSSTMMIATTSAARSVSHPLAMGDVLAGSLLRKNPLSPAGFATTSPSLQPVNTFPKNDQPTDATIVIAPSNTTTKGLAGSGNGNNLHGSSRTGYSASNQSSGNSSGMPAFGSASTTMTVASAFNASLSNTGGDHLNLSGLRSDRRRMTSIHYDPALGARFAAQPGPIGMVTGAGGLTSGIISSHALLRGSNPQGKLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNV0</accession>
    <name>A0A8K1CNV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNV0"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="35362" checksum="8CA52DCB57F8F7A7" modified="2022-08-03" version="1">MRTIRVDVQNAPRRAEAAMDAPFVVRVATDAALTVVQQAIATQLTSIGADPDAAAAFDMEVYDVQADSYEPLTHMNQLGRRARVNVVLHQNTQSSPDDTCLALPSRLFPVDTTQGEFQINGHAVLVGEVENSGLGTGLTTWDGSIVLAKYLEHRFGNGQLHGKRVLEVGAGTGLVGISAGLLGAEQVLLTDLAYTMDNLARNVELTGQHAQQIKARVQPVELDWFQPRSDLGDFDLILASDVVWVEELVRPLVQTLQTLVRNSQRSTRVLMSHQTRSVLTDERLFRELEAHGFQRRLVPTAELHPDFVSDRIRVWELELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNW2</accession>
    <name>A0A8K1CNW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003815</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNW2"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF9">
        <property type="entry name" value="GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425858" description="glucan 1,4-alpha-glucosidase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="CBM21" evidence="9">
        <location>
            <begin position="17"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="587" mass="63066" checksum="44FB9DD6F0D3B624" modified="2022-08-03" version="1">MVFAAIKNVIVIAAVTAACVFAQEVKVGSYSFDGKTLTGSVKVQNLAFTKAVNIIYANAANTWGNTCKAAYKSGPDSSNKEEWAFNCPITAGITQFYAEYQVNGLTYYDNNGGYGNNYKVTPTTTPTPTSTATPSPVTPGFQADITTYLDGGAATFKQFLLANISPKHIDGALPGSIIAATASGANNYIYHWIRDAGLVMAVVHSYYQNGDKSLEQTFWDHATFTKTIQGKTTLTGLGEAKYNVDGTAFNDPWCRPQNDGPAVRASSFIRFANTYLANGGSLSRVVDLYNGTTGVIKPDLEYVSKNFNDANNCDLWEEQRGQHFFTIAVQRRALHEGVEFAKKVGDTGAAAYYATQAAALDAKILTFWNSGAQSLQTTLNARLLDAALPLGVVHGDVGDGLFAPQDDRVLSTIYQLESGFISEYTLNQNVKVDASGLPLSVAIGRYYGDVYDGSGSTKGNPWYLTTAIVAETIYRAATAYVKAGSITVTALNQKLFNGAAPAGLGLNIPTGTYAKDSANFKAIIQGLQSYGDKHIRRIKYHGSAGYHFNEQFNRDTGFAQGVTDLTWSYASMISASAARNELKALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ14</accession>
    <name>A0A8K1CQ14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ14"/>
    <dbReference type="OrthoDB" id="189102at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="79"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="665" mass="73633" checksum="D55B1F3FF5C3B1FA" modified="2022-08-03" version="1">MGGSCSTLPSMTEIDFESYRGHRYSTEVPNTRDATHGAARQTETIALDESKLTMYETLLKGAAVDNGTRALYGTRAINADGTRGEYEWLTYNEVVARTDVIAAGLAKFAGLQRKSMVGIFSKNRVEWCLSAHACDRMSYVLVPVYDTLGPEAVPYIVNHTEQTLLICAKEQFDTVLKCKDTCPTLQYIVQFEELTQEQRQRAEAQGVQVKSFREIEELGKSHPLPADPPSPEDISTISYTSGTTGNPKGVIMLHKNLAVLTVMYADHLRLTQDTVHMSYLPLPHVLERCSVSTVVGIGGSIGFYSGDVLKLMDDMAILKPTCFITVPRLLNRIYDRINQKISTAGGVSQFLFNHAYSSKQASLADGYKTHAVWDRLVFSKIRAMLGGRVEFVLSAAAPLRAEVKDFVKIVLSCDIIESFGMTEISGGVVMSTADMPLGAHVGAPLPNFQVRLEDVPEMGYTSKDQPRPSGEITIKGPSVFAGYYKDPKMTAEVFDKDGWLHTGDIGCWNADGTLCVIDRKKNIFKLSQGEYVAAEKIENIFAKSKYVAQIFVYGDSFQTSLVAIAVPDSDVAQVWATSKGLSNEESTLEMLVQDPDFQKEIMEDMTRVGKEEQLRGFEFIKKIHLHAEPFGLEQGLITPTFKLKPPQLKAHFQKQIDTMYAAASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQA6</accession>
    <name>A0A8K1CQA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysosomal Pro-X carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQA6"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000007">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF120">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="63465" checksum="10CECE04C05ABD33" modified="2022-08-03" version="1">MSASELLPMLRPHNGAIHRRHEGFFKRLPLICAVVGALLAPIVLFVDFHSAKNVNTNDNVKNVSINNINNFTPLRVEGLSDAVTSAYELNPDGTPNLLKECKELYFTQMLDHFIANSPTYEERYFVCDKYSRKDGVIFFYVGNEADVELYLNNTGLMWENAEEFGAMLVFAEHRYFGKSVPFGSEVRQHMQYLSTEQALADYAVLIEAIKEEYKLDVPVVGFGGSYGGMLGSWFRMKYPHILDGVIAASAPILAFIGDEKPVDMESFARITTYDATPEAGSSEQCVPNVRRAWQVIRELGKTEDGRKDIASAFSLCETQNLESEEDVEGLIQWIKSAFDYLAMGNFPYPSPYMMNGKSVLPSYPVRVACDHLKFTYAESDHMGLLEALRDGVGVYYNSTFDAQCFEMSAPSNESAADDDFWNYISCSELYMPSTFDGKNDMFWSVPWNQTADDETCIKQWNINLRPKWAVTQYGGRKALKAASNIVLSNGNFDPWSGTGVLEDFSDSVVYVPVEGGAHHLDLFFSNDMDPPAVKEARATELKHIKKWVREYYDQIKSREKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQR5</accession>
    <name>A0A8K1CQR5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bud22 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQR5"/>
    <dbReference type="OrthoDB" id="69179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55678" checksum="7EE9179181601EA0" modified="2022-08-03" version="1">MVSMTTMSKRKAFTPHEKYMHKSSVLLQRESKKIRVFLVRKALQQLKQAREQLAAATTAANEVEDDDERKQKRKAGKVKKLTAQVSKLEREHALLKTLELKRVVAKAFEQTRLVAEEPEEESDDDEEDEENARRGYHSGDEDDGFNSEDYNDTPMPSARASDEEEESEAESESESEEPKDEESEAKKDRDDEEEKGVEKMETEDEEVVQEPAAAAEAPKSAEEQADSAMIAQLVDRVLAHNQMKPFLDAIRQYVEKKEREDAKKARLREKKALKRGQQNLIGGRSARAPTSMFFGSLSGGPDDDDDMEAGNGGYGRMAGAEDDIAEFLGETKKKKNRPGQMARRQKAMRQEESLRRQQDRANGVKRRYHDRDAELSKYGPSASLLGPSASKYGPSARPKKAKTTENKSSSNRRDNSDGQKKPWQQSSSRDKPANRDDRRARPESSAPKRPAAPPQRKPEVEPSHPSWLAKQAMKEKQKVSINAFAGKKISFGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQX3</accession>
    <name>A0A8K1CQX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQX3"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="118" mass="13164" checksum="20E55FB75E0356FD" modified="2022-08-03" version="1">MTSDVVVRRYVHGNHIYVAELCRPEKMNAFSHQVYEQLIQTIEEYEANDELHALVITGQGKYFTSGSDLWQGLSVDDEGNEILPSKDWPPRFMEAIIQCPKVLVAAVNGPAIGIGVTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC4</accession>
    <name>A0A8K1CSC4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC4"/>
    <dbReference type="OrthoDB" id="60138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004846">
        <property type="entry name" value="PRK06197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="323" mass="35103" checksum="6FAAD90999F61E8C" modified="2022-08-03" version="1">MISNPVPAKWDATRIQSLRNKLAIVTGANCGIGYETALELARKGAHVVLACRNEGRAAEATNNIRAELRDTPGAGQVEFMQLDTSDLSSVSRFASEFKKTHDRLDLLINNAGVMAIPHAESVDGLEMQMATNHLGHFALTAQLFEVLKASAPSRIVNVSSIAHRTAPTFDEKKFVLSKDKYDQWTAYGNSKLANLFFTFELGRRLESNGITGVTAVACHPGSTATNLITAPVEKSGCLWRTAWKIVGFLPIYQPAPMGALPTLYAATAPGVKNGDFYGPKGFQAMWGYPTLENPSKQSKSVSAAQKVWEMSELLTGTLFPIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC6</accession>
    <name>A0A8K1CSC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011053</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC6"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007949">
        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="64"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="500"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="490"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="582"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="508"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="547"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="606"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="705" mass="81493" checksum="57ED93A8AF3E9C59" modified="2022-08-03" version="1">MAAVNASRPDVIGKLPQLQNMVKRDPEGYKSEFLMQLRHYESEYQLFELQPTKESAHFGALVSFLSHVAKCYPVEMAEFPNQIMKLLRENYLVLEMDLRKTLVQALTLMRNRNLIDPITLLKLFFELFRCPDKRLREILYNHIVADIRQLNANSKNIRVNKALQNFLFDMLQDENENAATKSLQVLIDLFKRKIWHDTRTANVIATACTGKNTKLLVMAINFFLGIDGDILEEEEKEKKEKTATVEVDYHSHSKKTKKRQRDTIKALKKNKRARQKEITFQATFPAIELLNDPQGVAEKQLKVLKGCTERFEVKLLMMNFIGRIMGFHKLILLPYYPLLQRYLQSHQNNVTQILAYLVQSCHEDIPPEELLPIIKSIANNFVTERCSSEVIAVGINALREIFRRVPLVLECEGMDALVQDLVMYNRMRDKTIVMAARGILNLIREIHPALLKRKDRGKFHDEAARPKQFGELVAAEGVEGAELLEEAEAAGRFDGEDNQDGWEVASSESEDDDDEWIDVSSDEEGGGNDDEEMDEDEEENEEEGEDAEVKPKKDQKDRIDARRILTPKDFERIEMLKKEREAAMKDPKVRRKRKADEALAAAAPKNEVEMAKVKPEDLEGYAKKKRLTQEERLRSVLEGREDWKNKKKGGGTTNTEKKRLKHFMMIKKSRQVQGKVLQSARLVQRQKTQQVKKILKHDAKKRRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG7</accession>
    <name>A0A8K1CSG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSG7"/>
    <dbReference type="OrthoDB" id="124020at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="584" mass="65166" checksum="9AD6471A58FDB211" modified="2022-08-03" version="1">MIDFKRYFCGMSMLEWFYTFLTATTTDLLDAELSSQFQKALPSQEPRRIAIGLDLTSSYLKTSGLKQLYQILAAYAKFEPDQDESSSCQVVQYVITSLNLSQSNLSEPQDYEILTKIMLLQSPRVAIQHLNLAQTLSPTPHIESISGFQKFVQRVVRDDTSNLQELVVGGGAVDYTHFAAICSALRYSTKMKALRIEQSPAILVPVNSSAVWSWFALALMHPSSMSKLSALAIPYVHIFAGDVAKAQQTLASPHPAFVTFATKSPELAETIEREDDVQLNVAGKTFVTVKRSAKLRMEPKTRGRAIDLSKNAIDRPLEVVATLSKWTCVIVPGYGFGWVGNAAIVTHDDCEIVSRKPIPLRSFMWVSYSLYNGHNIGTVEALLQLIGERLTALYLSRTQVMDAELARILSYCQSLKHLEIPSHNLRSLGFLREDTPRSLRSLNIRPQAPWQQDLLDPPADQIISDLTSFLTGPSSSQLQQLAFELSQDDCNQVKQLVSVLRQHPAVEIVNIAQNGPWDGEHIHDELKTLDDQIIGLRSPPMATKLAFLSVIHQNERALGRIDAILVSMIFTFASAVKQRRVSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CST9</accession>
    <name>A0A8K1CST9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CST9"/>
    <dbReference type="OrthoDB" id="102059at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="184"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42763" checksum="4F4AA44D2D3C1EBB" modified="2022-08-03" version="1">MLAFNPEVALTAQTARPPRRWSISGTTDAQGPLASAIASVRRQTSSPTPTPTPPPPPPVEQAREKRQRRRSVDMSPLQSSLKKTPTALTAKLANIIDPKKIKDALHWGNQNQLYNNDPHQHAKERRVHFPVVDHLLQQEFDRPETTEEEKACYHYSKLELLEMVVNAKRAQAQEPGYDEKSDDTIIEQGYLTFPNEHHFFHQKRYYCLLKARQIICYSSPVHAAKNVHLKWRFPIIKVQDCAAMSMQAKITAFGAHLPSNIGQLFFVTKANGERVLVCAETKRAKRHWVHAITKLTQVHECPFPICPPSLRQKTSSSSSTSTCTSEDDNDGQSPDDETREKLKRAIMKCNQQNDRESAYSHPELPRAVDDLMVHLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT34</accession>
    <name>A0A8K1CT34_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005886</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT34"/>
    <dbReference type="OrthoDB" id="272091at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="185" mass="20804" checksum="9AFFC58117CB1759" modified="2022-08-03" version="1">MLQNALMWTIIAGGLLGVVGVAATASHTLAASFFLAVLPFLVFAGLTIINARNSAKRSDEHVNRHVLRVSRSVYERLDPEVLQLFLSDRDFTSSDYERLMQLENFNEKKHDGASESDIRRLPVVRMTEQMRRASKHPACSICLVNFEVGTHVRMMPCFHHFHPGCIDPWLKDKAQCPICKCPAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTD5</accession>
    <name>A0A8K1CTD5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTD5"/>
    <dbReference type="OrthoDB" id="161958at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="142" mass="15592" checksum="013391B802163A77" modified="2022-08-03" version="1">MKRAIVGETSFFNERCKLTSAIVVLNAIIIAECVVLLVRGTNPFFHSMDHPTPAYFVFMVLQILYLTAAAVFSVAACAGKAKMVMLNRGLFQVVTLTNIVYAIIFFVRSDVSRGLAMGFLAITNVLGAIVCGRFVVHQLSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTD8</accession>
    <name>A0A8K1CTD8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTD8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="70" mass="7685" checksum="A81B2F0A5DC31F48" modified="2022-08-03" version="1">MMTTPTMTEATASASVTAETNGTTAQETAKEDAQVVSEKMQQSINNLHAFSLDLQRLRTQMQARQAVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU75</accession>
    <name>A0A8K1CU75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CCDC81 HU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU75"/>
    <dbReference type="OrthoDB" id="125906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026295">
        <property type="entry name" value="CCD81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040673">
        <property type="entry name" value="CCDC81_HU_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028034">
        <property type="entry name" value="HU-CCDC81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14362">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14362:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14908">
        <property type="entry name" value="HU-CCDC81_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18289">
        <property type="entry name" value="HU-CCDC81_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC81 HU" evidence="2">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="CCDC81 HU" evidence="3">
        <location>
            <begin position="95"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="54287" checksum="14418B3D5B22492E" modified="2022-08-03" version="1">MASNGLLRECVQQLKSSKHDYEKVLGGSVEVVWQSVSSAIERHLRLKKGVGVPGLGKFSFIRDFQPLTPVFLLNDRFISSYGVSWKRPPPSLVIPIAELNMSVLGSEAGLPKDQVAQTLDAVCAFVGGRLQKGSASGRIPVGNVGFFQCEGKNLQFVFDPSFVKSLVQSSNDAKPNVKPAADPIKPTVQPNSVANRTSIAMTDAIGSISQLSLSRLVNEEPDSSSDKSSDQKNDKRDHHRHHKHKHRHSKSTPHLPLSTQSDTQTSTSTQSQQILPRFLMLDPLRAPPRHLTSDSKYARVQDSAYERETEDVKNRVARSAHEVEEIARRTKAAQLRYLQTKAEKSVLEREMNAFLHGQMEFKRNAKQQEDARRSSAMEYDAVKILPRDPIVTAAQRREVKLKLRRRLNDQVALKDDLAKQKRAVDQAESAYFLSKLQLHAAHEQEERAERQRIEREALVAGWTQQLAVRAQHEQLHPTRKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUN4</accession>
    <name>A0A8K1CUN4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUN4"/>
    <dbReference type="OrthoDB" id="2340858at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="23472" checksum="5527DF27195AC2C2" modified="2022-08-03" version="1">MNDATNSTNSLRGKIFELLSHKRFLTQDQLALEFRSLDAGDIDTEETNQPDLAAAANVARESSIFTLTTQEKMEEKRFAKVDEICKVPGKVMYYRPRAKNFGALDALIVDGIKERCYGLQMTIGKTHPVAWKPLYDVLKHLREIELAEDFCLYFVVPPYMRDSYKRQPIRTNKDDLFKNPDDVGRLPQFACGVNAFGIPTARESKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUR2</accession>
    <name>A0A8K1CUR2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUR2"/>
    <dbReference type="OrthoDB" id="106500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="302" mass="34396" checksum="3B73DCF3C545D006" modified="2022-08-03" version="1">MPRVHIFTCEGTVNAAQAAPQRYVFYVYEDGGMTAQVRPTDEDMGFVYDGQATPQANTSAEHPAFDCEFKLARFWRHRPRGQFMKCRAQLSRVKGMKGMYFTIRAVHDDGTENNAHAPSRRISPMIMFQLPTVSYRVEEQQHSLAPLTSGFYKMEGSLVATSGRVRQIRMALELRPDGTVQDRDELDAAVGLEGTWSSGYLHIKFDRLEFEGVPTSGALRGYWTRTSDDVDDNERGRFELRVLDSKRLWSTRSHRDYPSSFRDSTKFLLLKAVRASPGTTYALPSTLWSQILSYCSYEHFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW91</accession>
    <name>A0A8K1CW91_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW91"/>
    <dbReference type="OrthoDB" id="6022633at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031367">
        <property type="entry name" value="CCDC24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15669">
        <property type="entry name" value="CCDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="40143" checksum="80B24BBC914CFEDC" modified="2022-08-03" version="1">MASGECFHVRRLLWEELTPLIRPSEAEELRRAIGTRLIEDNAVLQQELSALVEMLSEFQQQTDSVRDALLKRRPRLPEPPGRALLLDKLKLLANDLRESQVESLPSTKEQELLQYVLTTDALQSHVLEPPSTPRIADLAITPRDGIVLRPGTSSGRRPGTASSSRPVSRGSTVSAASTASTILESPEVRQRLNVEEIDSIREDVRDALEEEQQQLMEDIEFIQGCIDMEQDLLEEDRRQVLAMRPPPTLQELHDFRKTLEQTLEQQEAVARVEAMPSFGTRRPSLEPVPPLQVRPSARSRSISIKNYLSVEEDDEDDEWRRERSGRARLSASSSTKVLKIRHVIQEARDEPFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWG1</accession>
    <name>A0A8K1CWG1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">B-related factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_001659</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWG1"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20553">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000066">
        <property type="entry name" value="Transcription factor IIIB subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="13">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="458"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="606"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="534"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW69503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="661" mass="74549" checksum="FE0A5F57A3F69FA6" modified="2022-08-03" version="1">MAPSQQTICPTCSCTEIDIVDVSGEAVCVSCGTILEENNIVSSIEFQESGGGAHSVVGQFVSSTATKSYGNVGTSGRNYGMESRANTLANGKKKIRQIAGMLRLGDHYVDSAFRLFALALQRNFTHGRKAQTVIAACLYIVCRRERSPHLLIDFSDKLQINVYVLGGVFLKFCKLLQIHLPLIDPSLYIHRFASQLNFGQKTHSIATTALRLVATMKRDWIETGRRPSGICGAALLIAARSQSVMCSLHDVMDIVNIGERTLKQRLYEFSLTPTAQLTYDQVGRLEMSRVECDPPSFQRHREKEVMEMLLLESERLQLENGRKRGRREEEDVLDGSAVQKLKELKDEEMSRFLSGDAFYKKRAGGLLTNSTNANGQGNVGGNDDNSVAGNEDEDDEDIDYGFENPNDQIVNRASRLAAQEVLSRVRRKSARYIMRKREEADFYKTIERDLTLALEDENGKSAAKVDDRSGKTSSPSSSKRQRRRSSEDEVSFSSRQRRSQARSRRDDDDEDYADEEEEEEFDEPEEEDDEDENADKGRENGVRSRGDDSDQSKTKKKEENDSFSDLDDDEINSLLLTKEEAEKKKILWEKMNADYIKEQEAKRLNGLAHPEVPKKKRKKKVPDANVPPPDTAQHAIYKLKSRRINYEVIDELFGEAASNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAD1</accession>
    <name>A0A8K1FAD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAD1"/>
    <dbReference type="OrthoDB" id="104692at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="132"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="429" mass="48271" checksum="1A6E2C1303B92AA2" modified="2022-08-03" version="1">MQAQSWTDAESLPLWIPRRKDGAPDLTTSVARNFFNAAKPPPPPRRDLYYKERLTNREFFKAVNIERRTIIDRVTIPTPMPETRTLRGVFEELSESSANRVTRSHDDDDQLAKMPNTVVEVDYATDLTINIDKSDTVLGTGSFGVVYKGKWKDQIVAVKKLHTSQLTKKDRRMFIKEALVLGVLGAHPNIVQLYGYSLNPLALVMEYVPMGSLSYLLHYCDDPIAEAKMTDGRIKLNLLMGITHGMMQLHACGVTHGDIKPQNVLVTKDFQAKIADFGLATFRAKTSSITSSHRMVSSSVKDEADDVEADPEAVVCGTAAYMAPELLESGHVADELTDVYSFGILINEVLQEEEPYYQHLRKFVGKGPYAAALAAQQGLRPVMDERKVTSELKELIERCWSRREENRRPRFDEIAEIFELCSGIPNSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAE1</accession>
    <name>A0A8K1FAE1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAE1"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="341" mass="37658" checksum="FF26C4654A091287" modified="2022-08-03" version="1">MGRYGGGGFVWHMGAHLTGSIILGLSYVKPEKFVSYVRWGLFVYFLIASLDVALTRYHVWKCNPLTPQPKRFALVTGATNGIGREIAYALAEKKYSVIIVARTEPILHRMRAEMELVNKPIEVEYCACDLATSKGVQTLFDFLKEKNFVIDVLVNAAAAVEQKDFKDLPAEKVDELLHLNLMAMTKITHFIVPDMVKRGTGRILNISSLGAVASTPTAAIFGASKAYIASFSQAINYELRSTGVTATCYHAGAMEVDLNDPAVSKKALTTVELSYTTVVHPKDSAKYALDALFDVKDVAYDSYLNHLWAFLLRGLIPTRVGQALVAIAWHKPQDAVKLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAT5</accession>
    <name>A0A8K1FAT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013287</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAT5"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000145">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="67"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="263"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="761"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="800" mass="89789" checksum="85A5DFE3C7534D42" modified="2022-08-03" version="1">MPRDQRRRSRSRSRSSARRRRRSASPSPSYASRDRRSRSRSRRRRTEDEKPAKAVELPAAAHRHELLAALRAHQVVICVGETGSGKTTQLPQYLLDAEDLVSSSHSVVITQPRRVATVSVAQRVAEELAAGPLGGRVGYSIRFDDRTSTATRLKFVTDGVLVRECLRDPLLSQYAVVMLDEAHERSLHTDILFGLLKQVLATRPDLRLLVTSATLDTKRFAAFFNKAPIVTIPGRSFPVDIFHAKQMQIMGTRGPISSYLRSAVETTLQVHNSEDAGHVLVFLTGQQEIEDACKQLRRLSDETTRPDGMKMRVVPLYGALSGRLQREIFAPVDARRTRKVIVATNIAETSLTIDGVRFVVDAGFTKQKVYNPQTQMEALVVVPVSKVSAQQRAGRAGRTAPGKCFRLYAKESYAQMLDESIPEIQRTNLANTVLYLKVLGIQDVLGFAFLDPPEEDAMLDALQQLYELQALDDKGVVTPLGRLMAEFPLEPKLARALMEAVVLECADEMARIVAMLSVENMYVSAKAKKENKDEEQDGETARDDVMLTLTKEGLVDDRGDQLTYLRVLTAFERVSAEAQRRWCEDRDLQYRALSTASSIKQQLLDILRKLPADQVDELRSKSATDDEARRSSRSTRLRRALCAGFFTHAARRCAVQTSVYRSWSFENDEEGGDGRGKSQTKNVQLLHFHPLSTLNYVSPPLCCIYQELVATSRPFMRHAVQVETSWVRQYSQGRAQVTVQQLYALSGREAPVENVVHLPKMEEKANAPPPVDESQQQKAKEDAVAAARARFLARKQHQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBG8</accession>
    <name>A0A8K1FBG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBG8"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="320"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="476" mass="54059" checksum="A890528EF0B13854" modified="2022-08-03" version="1">MNRLRGVPSALGAQTASFFSFVNPQSLVKSHQESKIVPFSPEEMYDVVADVDQYHEFLPFCVDSKVLRRPNENVMEAALRVGFKVFTESYTSRVIMKRPEKIVIKSIESPTFKRIESEWYFKRLPDPSSCEVRFKVTFEVASFLHANAIQLFFDDVAVTQLNAFIGRTAKLQSVKARENADRRADEARMNRREVPKPASKLSSVPKAPASSTETNTESARLSPASQIAASLVRDDVWSQDYVRLKQVFEKYSDDEGKMYFSGFLKACRDLGCIYEDMKQISENSALAGAVFSSFETGTAPRDWLDLEEFSVGVYLMAKGSVEEKAHSLFKLIDRTGHGKISREDLTTAMQRRIRTVKTIFPKLLRDQLEIQMQHENVADIPASVEEAMAKGLHAIESLMEEIEQEIPLAVNQIFLEADLDQDDYITTDEWLFAWQTHPELVELMTVDGMKKVAQWASVVNPDDDNTPLDTRLTYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCA2</accession>
    <name>A0A8K1FCA2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCA2"/>
    <dbReference type="OrthoDB" id="58802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="287"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="337" mass="38481" checksum="70AE2AB6C3D2215D" modified="2022-08-03" version="1">MGMMAEDGSDRVTTARERLVAANLFMRYDYAWKANEFKQCTSRLTGVTCRILYLYTVWQHAAETKRTKIQLDTENAESAAVSSPRNVYIDANGYPEFEHQVVTACELMGFDVITNQDERAQANLVFVYISPHGEERVDDQYAGFQSITQHHESIATETEQRPIFCFLLGEADFLEPPATTETERLRGLSGFAISQRFTPILQEAQYSSAAHFAVEFVPQVVKDQSERGQLNDLMNQFGCMDHNMIHHTEKWELYAPTESLFCQDEDVTQADEDEARFWLELTKGKTCDQCHEAHEKLFKCSRCTSAFYCSRDCQKVAWKLHKQLCGVQVPPAETAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCA9</accession>
    <name>A0A8K1FCA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCA9"/>
    <dbReference type="OrthoDB" id="77369at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="706" mass="78829" checksum="AA1DA738B8E63D15" modified="2022-08-03" version="1">MSQFLKEIDLWYTLHHPNVVKMFGACHVSSPPLIVCEDATNGNLADFLASSDGGIRHMWRLLLEVALGLEYLHRNQVVHGDLNLNNLLVGSDGAARVADFGLSIIGSTGSSFSATDGSGGGLRWRAPECLKQRPTFESDVYSLAICMIEAVSGEPPYSLEDDVTVQKLVLSGQLPTRPTQMSDEAWKLVVSMTTFDPSKRFRLTDAISRVKLLAENDCENATWSPGNTTHEAEKPDQHTQPSRGNEKTDTYAESYPLSEETGSDGAVDVRSVELTIVPASNTNQHFSKEIIHLNSRLTMRELMVSSLENGSPQEKYAALKWLYRKATDEAESQHIKQAGGHQLAFKCLQDPSLAVYHHVYGFGVLYRMYIAHAISYTDFKVVEEKVCTLRVYKEAELKEMLFPRNEGEAAEKVALIQKWESYKKDSSPFIPALVTMLRTVQAEEEEESVLALGTFADLFSNVHFCWGHHFKFDVLIAPATEFVKSGTELQKASATGLLRILVYHRSDYCPEIKAAAVLEPLVKVIQTPTNNPKFHSDAMFVLGALARKDPATRSELIKLKPFGTLVQFVQKGLPSQKEDAANALGSLMKSAQGRREGNDKMWRPSEPISAIYALVSGTQTPASDKKPGQGRMTAIINRKPLQPPRFSGYQAHQKLRSNEELPELLEALYTRNQNWSRLSTPATQSKAIQDEELYLPPPKRSRRFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCC7</accession>
    <name>A0A8K1FCC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCC7"/>
    <dbReference type="OrthoDB" id="58570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="877"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="652"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="943" mass="106566" checksum="1025529F2C88B3FC" modified="2022-08-03" version="1">MQRPSTPRQRHRNGSQRSSSLQSRSSSEATFFSPRQTSPKNRRHHEETRGDAQHFYSLRAWKRWCLGAILRWELVLRAVFVEIPTMVFHRIEGLDKVVAFFFVYVMLQALAILWGFLFNVGAILGDNMISILMMPYVQAICVLLTHVSVIGIVLSFGRATWILTWQSTQNFPMIRRIIAHECRPQSVIVVAALPMLVLLPSLIIVPIVCAQAEDDMGSWTHAVCKESYLKFVTDKHPIFQRSLRLATNIAIWQFIQACLEILPRWRAGLSELSMLTTFVLGGLLFTLNSVGVVWGFEWLARHVKYHATPLSDLTAAQWELFGLGLLTAWILWFLFLTWCTSDSRFEGKGNQRRLVGFFERLKYTFVVGQAIIFFRACVHPDMGFVHAQLELTIINLLLPSIYVISLVVLRMMTQISWTSLTLNGPVSLVLASGIYVGSKMTQRPHSFFVVALFLFEVSLRTTDAVYTLSRKGRVPQLLQQMLQKTTASIRKPPTGHGLMKKMVMLAFIVLFVFVAVLAGFSVLSVLQTNAKWFPDATSIVFHDESTVEIHHTAIVKLHLGLANTTNKAMHVDIPRYASCSNNWNGLDIVDYALLAEAAYFDPLSLDIERFVSTVFNHDLGEIVIRLPALNTKTGSKLDFYEAFIPSLNTSVISVRGTDIWRFTDFIEDVKMFIEPVIFTILSLVFPTIRIWPDVTFSTLIELYGELIALFGLQHEFWYYHELLEYVASIQDRDVVLTGHSMGGGIARLVGSIVGKTSVTFSPPGFVQSYSKLVHDIGGKATKVDRANLHHRSVTVVPEYDPITLIDAQAGMIQKISCNTPHLSMQLSCHMLEGTLCNLLEHCGDARNRIASCKFEHKITSLTEDILPKLTAVMRPEAIVTAFMITSIIISVLFRRRRRKPSLQSEFMDDLSPGRGRQMSAATHRRHFANAPKQAGSQRRNSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD47</accession>
    <name>A0A8K1FD47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD47"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="190"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="332"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="474" mass="53472" checksum="0AAD234A421B59CF" modified="2022-08-03" version="1">MEVRQQALDMDSENDDDVRDVMTATEASASFLTATQVLEEELQRSGLCVSLNEVPHIFQQADHFVSVVLSRLHRDPTSLEPRLWAFQSQHNRFWALKQQALVGSCEASRGSKAYTSAAAENNDAALVGKTWRPCCFRMVGDSKMKQWQALGEMNQLEAQTQFVCLVTELAPDWMHPLNDDAALLRTWTPDDESDRCHICDETFTLLNRRHHCRRCLNIVCAVCSPRALPLRAFTEIPGKLQRVCNACVLEMEQQRSERRTGTVPLNGKRDDNATPPETLVRKPTYAFSFLDDLNSPAQETDVSPPTPSLLDEAASVMTRQSSLPSSASVVSSTIHCGVLELLHGAGFRKNWHAYFFVLLVRKGSLGMFLSESDHIEKKKRPAAVFKLSGYTIRVKSQKRRPHQFRLTHETKKPLHFAATSIVEMNRWISHLIKAIDNANDLETQTLTTRTQTPSPKRATKPGEFGDEQEDEIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE64</accession>
    <name>A0A8K1FE64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE64"/>
    <dbReference type="OrthoDB" id="72938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03801">
        <property type="entry name" value="GT4_PimA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="26778" checksum="7889817127665962" modified="2022-08-03" version="1">MELANLMPERLDVDVLIAPSHFALHHPSVARSVTARSRHVMFTGVDTTLFAPSTNIFRSEVFTIGYVGRLSTEKSVGVLLSVAKLLVDRGIPCRVRIIGDGSQRERLKALTASWNLSSIVTFTAAIYDPPRLAEEFQRLDVYVSPCFEETLGIAPLEAMSCGVPVVGFATGGVGEFLEDGVNGIAIKEPTAEAMTEAIMLLYQNSLRQRLGAQARQTVEHRFSDRRGIQQYLALYERLRKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFR6</accession>
    <name>A0A8K1FFR6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFR6"/>
    <dbReference type="OrthoDB" id="167194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="711" mass="79644" checksum="FB97A1C4341F5564" modified="2022-08-03" version="1">MTVLENSKDRVHTYGKQAIMAVVQVVAPAFLLNALGPVIAIFNVETQLYANPEARMSKLGRLVCRGVLSVLTLPLVSTSVGEIVKVDPRIVSEDLNKFDLMVWNNSESHPIVRKGNGSFVRTNLTNTILRGAVLPYATSLRHCDIADSQKTNAYTSVGYEFLTNDWHSRILPVGLKPSKMYAVPGSSRESLLVSNLTLSRDEVVVFETLFIRAVYLYIDEVLVQHTALGGPNVATLKTLKTDCIAYAKTHDVSASGDVDHVQHLEDYVRNYFKMSSAWTTVLGARVEDIVVEAGNHFFLQERNVQCITLTLDIPLDNAIWHRQLKEENGELVDTKTLYPGSGDVIYEFDVANECGPDTCGIENRGFAPEPKVLALADCPSTSFEDIYGVELENGTSCDNSVSGSSMWLFGFGRRIEGDTFELLDPPANPKVRKARAINTREFHRASIGYFMFPPEELDQTFNAECWADSDCKEHVVLGDFGSAFQFEKNLAHSRPLLTRYTSGARVEYEILRPENFHKTVWDEELKDSQCSGKMERSFIRTRLNNVFMEDPVQVMYTAGLFYIFQNAKVIPVLLQPDSLEFQGNVRWTQHTFVLAKWHSIFGVSFAVAIVLLCIILLGRHQRISLWSARKLRHLDVLTRVLNDSATFPTSCTDLVIKQGGLQPTAVPLSDLILRGLEFESADGKLEYARVILRQPIDNQPSPSKMKSESVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGY1</accession>
    <name>A0A8K1FGY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGY1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="79930" checksum="1BA7F02D7490CD0D" modified="2022-08-03" version="1">MQVVVDEFKDAEIFGAMFQNCQHIGYQPLMGKAMDHIGWDKHIDLFIGKGWSKHLSSIIPDDQTIASFMNLASSLLTGAMPSKRREKLLEAASLRPPLPTGTERFLIPPDETTLHHFFISAYPFSGEAVKAWVDVEYWEMLVAVVAPAFVALARSLGHHGLYAAFYGDCEHEVKFVTSGYRMCLTYNLTSSSTAQRPKENSGAEVYQKVSDAVSSVLASTSSQGQFTYILEHQYTQRGLGFEFLKNRDLLVAQYLASHCAKETNGRYGVHLARAEYTENCEYPRVVELKVKPPFIAYGESMENAVTHVAPATRDGYGDKILTYEVKTQMVPTDYFNKFPWKEEDERHVPYTGNEGDYSENWYATAALVVRPVVTHVEDTANRERRDCATTLLKSDGDWSTTDEEFVRMMNVVVFELKEADLFMMMLRNCNDFEFQPLLAKAMGHLGWDQGISAVITTKCPVQMAVNLVASLLTVDTPVDYRDEILGVASLRPPLRTSVYVKGLLPSVSLLGRLFSTTYRFSDAIIDAIIDAIIDAWVDVEYWEMLVALVVPAFVEFIKSSGTLNENIEKWRVKLLTKIQAGFSESVSWALSIPVSWWSGCCAECDKLVAFLRSPTARTHTLAGSDTGHFRRFFLEYFTERILATIERNDSNWRELQKKPTRKKWRVKATNQIKLLRVPESDDDSDREVKRQKTLEEWWFDNTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX6</accession>
    <name>A0A8K1FHX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHX6"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035435184" description="Peptidase M14 domain-containing protein" evidence="11">
        <location>
            <begin position="25"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="179"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="491" mass="55580" checksum="8C684F2BB26A137E" modified="2022-08-03" version="1">MKLSTAVYGALMLTMTQLSAPATASTSTHVHLRVKHPQHHETPQHKHLYHVTGPKSSFKQLLDPRIKADLNLDVWSIKPAHKTHGKHQDVQLKADIYATQDAMDKISSQQADAHLQIGSMKATVHTKQQWKLHVKQYIDYDLQEQQDRQAVRACGNKTQGYMDDIESLDKYTSSAFFDCFRPQDEVFTFLDALAEANPEYVSVYQNASTTFEKRAIPAYKISTQGDNDSKKKKKAALYTQALIHAREWQAGAATFYTMAALLDGLRAKEHAVVELFKTYDWYFVPIVNIDGYIYSWEKERYWRVNRDNKASKEFEGVDLNRNWGPDEYFNLDPSDVSSETYPGPHAYSEPESKGLYDFIMDIENLQGLVDMHSYGGQVLRPFSDSFDSPVEPFGSALVALADAVAAATSDEYASMPALDLYPAYGCFDDAFYREFNFTVPALTIEVEGHDFTAPQKTIRKVGANINSGLRQFAKEVAKYRSTIEKKGIKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI28</accession>
    <name>A0A8K1FI28_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI28"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="23215" checksum="5286E34B10E664A6" modified="2022-08-03" version="1">MYFTFVPRIGLDITDVHNIDGLVFHCKHYTTKLVDTAVYRLMNTATRADASEYRDQLVKDVNEALEYLAASWRECALTMGDEIHSLRAQVAALKTRAAEAEEEARIAKERTICRDDETSNNVAIDHQWISPCPPVAPVQVPTMLGRLRRKYQHSELRRDLLLKQSRLADSECLRVPRRRRRRLRQLQSLTQVLMFVQHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIU2</accession>
    <name>A0A8K1FIU2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012823</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIU2"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="204" mass="22777" checksum="ACA2EF6FB8C71486" modified="2022-08-03" version="1">MSRDYDHLFKLVLIGDSGVGKSCLLLRFADDAFTESYITTIGVDFRFRTVKIDKKTIKLQIWDTAGQERFRTITSAYYRGADGIIMVYDVTSQESFDHVNDWLNEVNRYASEGTCKLLVGNKSDITENRAVPYETAKAFADSLAIPFLETSAKNAQNVEEAFLTMASELITIREMVGDTNRPKGATLADNDGHQKSNSNGCNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJA4</accession>
    <name>A0A8K1FJA4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJA4"/>
    <dbReference type="OrthoDB" id="167659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34733">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34733:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475944" evidence="1">
        <location>
            <begin position="21"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="314" mass="32747" checksum="471D1CA5A2DB02E7" modified="2022-08-03" version="1">MKLSSILSTVGLLYLTVVNAAEVSVSVSAEASTDTDTKTFSAPKDKDGKQKIKTGAKFGKSGAKIDLCPSGDCINGQVITLAMSRLQEFDATGTSVAKADNFNKGTNAWTPVETIMINGVSASVTTFAGDIDVGSSTAKFNLTTVIFESTSWAMNGAQNLTIPAGALKFSIAIQNWPFATGTTDHYLKFAVTLKAKSKNSTTTLGAPKQTKGNATFARDTVDMGEGMYMDAPTKAVIDDMDTDISAAVEISGNLVEYVWRFPQFTELYYDPVVGSTDADATPADATAPSPSGASMAMVASSLVAGVAALSLALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJR7</accession>
    <name>A0A8K1FJR7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vesicle transport v-SNARE N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002360</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJR7"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF84">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Vesicle transport v-SNARE N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="24794" checksum="A2099C7DF9BEF61C" modified="2022-08-03" version="1">MTSIFDGYDEEYRALTSDISKKISEVATYEDEKEKKKTSIVHIGDLLTQANQLVQQMELEVRSLDAATRRELSKKVDQYKKSLASLANDHKTLKEKEERDGLFGDRDDIAMSSADHRNKMKAATEKSKGTTSKIESALRTADETEKVAIAITEELGRNREKIQAAHNKVKNVNDMARRGGNIVGRMSARDKRQQMALRVAAGFIIVAIILVIYFGIFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJV5</accession>
    <name>A0A8K1FJV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase C45 hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJV5"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047794">
        <property type="entry name" value="C45_proenzyme-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047801">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45_hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040521">
        <property type="entry name" value="C45_proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180:SF1">
        <property type="entry name" value="BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180">
        <property type="entry name" value="PEPTIDASE C45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C45 hydrolase" evidence="1">
        <location>
            <begin position="149"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="402" mass="44927" checksum="529CA2D66502CFD6" modified="2022-08-03" version="1">MTVSMTPSVSAWTSANVAVLEQFEYQGNSHFDFGKAMGARFREKIAERLAQNTKLQTRLLPYVQTTTEGKSIYAAFLETHETTFPEYMEELRGIANGSGIFFETIFVMNLSEEFDDAVPETYTAGAGSAFIKQKTLRCSDVVLVGGPDDLRVVAHNEDSGASDLNHTAIIIAKIGDKPKFVAYTYLGDLPSGAFGFNDKGVAFTLNFVQPTDTETGGLGRGFISRDLLWSTDSADAMQRIMRPHQASGHNYQLMDVNTKRIWNVEGAALNRYAGQEFLPPRERNNVTAFFHANQYQLLNISQPPYDSSLHRLKRYSESPKPKTVDEALQILGDQHDRLYPVFHDVYSHERGELSGWTLITIVFDLNAKKAVSYTGNPSKGQRELIWDLEQLTVEKISVQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKB2</accession>
    <name>A0A8K1FKB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW64004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKB2"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051568">
        <property type="entry name" value="LZTR1/Attractin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376:SF1">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54890" checksum="B7D7B387F242E249" modified="2022-08-03" version="1">MRMKTTTTTTPSTTTGGGMEVRAWEKLNPLGDAYSPRTGHTVACYDGRVYVFGGTDRRRRQQDLFQFDIATSSWSQVQTRGALPPRRSGALGVVHDDKMFIFGGYDGRDGNYFNDLYFFNFASLRWDEMPSSVAERPEARTDHIMVLHSSSIYIFGGYNGSSRFNDLWEYSLEKRKWSQVDAAGQVPSRRFGHSAVVHEGKNRLIVFGGWDGRDTLNDLFEYNFDTKEWKRLTTIGTSPPHRYRHTAVIYGDSMFVFGGVDKTHSRFNDLQRLDLTTNTWSEVCTTGSIPSSRTFHRAVVVSSKMYLLGGYDGTDRLQDLYAVDVGPLSPPSLLDICADYVRHNVDSILETTTFAGVSYDVLNHVIFKRDAEGSLRGTCKVCRAGRCCVYRVRQSENRQDATREVRSKTDCSQTKQFVCVCGHSNLHHEIIDEQSLYGKKAPDTTSSKVLMLCGSIYKRLFETTSALSTLSSPRRLCEATREAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKF8</accession>
    <name>A0A8K1FKF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKF8"/>
    <dbReference type="OrthoDB" id="270602at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02958">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="348"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="46939" checksum="BB319B4A852E0EDF" modified="2022-08-03" version="1">MAENHDALASFMGITGVDSTTATQYLELTNWSLDEAVNLFMESGGQGFGGAGGSGSAGSAMPPPAPAYSEDDIRAPDPSRRQRLFNDAFENVPIRRLHEQYRDFAAESIAAINAASNAPRITPAFGGAQEETDAADRARDLGSLFQPPVNIMFKGTYAEARALAKNEGKYLLVNIQDEIVFASHMLNRDTWSDDVVQNIVASGYVFWQNYWVSEHGKKFCNLYQIDRDSLPIIAIVDPKTGKVRQQWTGFLEASAMIEKLSDFAFSNTLDADDAMTDAPAPSMGRDINDATEDEQLAAAIAASMEGAGDGGDSPDYESYDDDETKEEEVAEEAEDEEMVELPEEPADGTPDVTRVQIRAPDGARLTRRLLKSDSIALLWAFIKHQIPEARQRAFELRTSFPPAAIAFSDTETIADRKLENASLMVKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM33</accession>
    <name>A0A8K1FM33_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM33"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="75"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="55843" checksum="5F7CFA80E5C7C27A" modified="2022-08-03" version="1">MAETDGAISAFFCVMLALYIIPAAIFTAYRVLQAPSKVLASRAFTVNAVALAFAIVAFWCCLTHLQNVDTSDVFDPYEILKISDSASVREIKKAYRKLGRELHPDKNLNNPNAHALFSRVVKAYEALTDPKGIENYRKYGHPDGPQSILMGFAFLSAFSGGGGGLFVLGYFGVVFAAIAFIVYSLHKSSGRRDRTQVSRRTATAFLEAFNERMSVHDIVELLLSCEEMTTTVGGEEDLAEAHQRAKAHDKVLKKMEAAKVLPADLLGRIKKHPHPIARENMIALYQFLRRNKLTGVPKPTWTELRLRKVLLELPYLVDIYATLVAENSVKRAYPSVTLVRTLGLLASISQGSFVADEEALRDQRARAADAGVELPRLALSNPKLFVADEANIQPGDWLTLELTITREHVATGERATLASTFFDQIDPKTEFRKEHLWLVVVDKHSSRVYAATKLKDLSQTVPSKLVFEGPGVAGKYEMEARVVCPVYFNAQASVTLPLVVESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMT2</accession>
    <name>A0A8K1FMT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Drug/Metabolite Transporter (DMT) Superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMT2"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37288" checksum="72DE8ABBB4682455" modified="2022-08-03" version="1">MTRFLTEAKNFACGQVVSVFSMSALLFAKRLARREVHAPILANLFFYLLLAVAYILYGWRRPSVPSGPAQDTVRWWLYPFLALLDVQANVCAAKSVVYTTFATTGLTLNLAIPFVFVICTCVLKVPSSWKQATGCGLTVIGGLVLLGGCASRFKSDDIEHQELYGWALALISAALYAASNIVNQWCLKIRGMDSMIDCLGMIGAWGAFFCVIETGLIEHADITAINWNSQVSLLFLGYTLALFAFYTAVYVVVHGSETTAYNVSLLFSSVYLMLASYYLLNETIDVYTVVAMVVMLVGLSIYTWSCAVSGSSNLTQSSFDALRAPREDYVLAKIQRVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN97</accession>
    <name>A0A8K1FN97_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN97"/>
    <dbReference type="OrthoDB" id="157554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="339" mass="39033" checksum="D5F9A56A3B0E7E0E" modified="2022-08-03" version="1">MRGDTTTNKRSRYKSTYYSRKDEIDALHREAAALARQLQRLQNDDDEENKSGAASLMENAILREKLKQSGMMLAEAQSILSHRMRAQVIHPMETFIHLTKDPAERRRTLMSFRDQKLHGATEFMVKRTRFMDLRRPHRHLESCEALNGDCIVEQFAVIPFEDVASVKQVYDGLLLALFHQEYAAWEKLGVLAVCESDDADDSSISQSRYLTEMAPGVDLEKNGAMFCRCTDGSDQLRVPHGLVVTDSIDEDELYPYDSEHRLRLDLSSIKLVWPCPRHDSSQSDTVSIVRWTRARIHRPHSGLPMEIQDHVRDLVPRWSDAMNKTVREYVAQHRGLDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ24</accession>
    <name>A0A8K1FQ24_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ24"/>
    <dbReference type="OrthoDB" id="148483at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="121" mass="13368" checksum="C9A56F126A0DA25D" modified="2022-08-03" version="1">MATADYKLFTPLTLGNDFVLKNRVVFSPLTRARSNPKTRAPTDLNTLYYEQCAGAGLIVTEATAISEQGFGWFGAPALYTQEHADGWKKVVDAVHAKGGKIVLQLWHMGRQSHSLSLIEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQD7</accession>
    <name>A0A8K1FQD7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQD7"/>
    <dbReference type="OrthoDB" id="41362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050461">
        <property type="entry name" value="Nitroreductase_HadB/RutE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43543">
        <property type="entry name" value="MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43543:SF1">
        <property type="entry name" value="MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="23625" checksum="EF70B7BEFFF77599" modified="2022-08-03" version="1">MASTDLRKVIEERVSVTEFAETPIPDAVVADLLRLTQRAPTAFNTQPYRGIILRTAEDRARVAESMIASNQVKVNGAPLVIAFAADLEPSKEVPRLQGLMKEGGAPQFVIDIVPGYLQGYSGEGTPAGLAWSYKQTSIAATTFIYAARALGLVTRPMEGFDQEKLKEALGLTDRYSVPIVISVGYPKGDLPTKGGLRYNPTDVFFEGKLGGSTAALFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRF2</accession>
    <name>A0A8K1FRF2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRF2"/>
    <dbReference type="OrthoDB" id="119576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="31126" checksum="C66AA39F22C6C589" modified="2022-08-03" version="1">MTRVPSRRLSKSCKNIRKYGERLQLRRRQRGAELSLTDDLDRLREQLSAVDRHLTLLDSISITMRQNAETSAMNMIKTYFHHMQRGFDSETAYDRDVTRPFICAMLTEDVKCQDFSGRNFFFEQWEFITKAHESVTMTNDLLMPLPVAIDDDSDVYIIKACGATSCRITRDALTKFFPHILRDEELVQWLIGKEYSYGYTMVLHVNTDGRVYQFESSIDLTAGLFSLMQDPQTTIKMVQSSKWTKGGNLSGFHPEVQECQYDIPNSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRP4</accession>
    <name>A0A8K1FRP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRP4"/>
    <dbReference type="OrthoDB" id="183084at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="57704" checksum="062ACFBF427F29F7" modified="2022-08-03" version="1">MLWRTFRDRALSFGGFTSTPSQPTGQRSRVTRWIRSCLAYYGIRGERFEEGFVVPEGLEIFLQIWQAYTTSKTISTKFVNQSFSVLIAVSAITHPVLSRMYARHVAKKRFGSVLAEFFLDITWSSILPLCVFVNYWHVGRTLTVERLLSTFPFGSYELAQREIRHLVILSWSQFLLATIPATSALIYLLSVLRILASAQVKESSSPSVALDSGRLKVTSSMRTRTLIIALAASQRKSAFVRWGHRLIVVSGIGISLTSIAATSMFESTGRIPDTSCGFRLYPWFVTDDACVVIALSCTQLQISGDLQELNSVFTTIDVASIGLLILSDCPCLVMPTALTRATSLTALILANSTIVDWPMDVAFTTASSPPLRLLAWNGIRLPSPPPGALVKVPTWPETLERVRIAGTDIDELAQRLTTHWHTVSSWTCIDCGLVTFPAVFVAMPKLERWVVWNSSIIEIPTLYSTTETSLWPSLRVVLWTHNTRLSSVGDDVWRAVSSGSVHTLSLASTGVQDIPVHRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Y5</accession>
    <name>A0A8K1C2Y5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Y5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="163" mass="18374" checksum="1CA8028721C03103" modified="2022-08-03" version="1">MSFMDVTSASIGHLRACYHAFLQRRLQRGAASVRTRQGFEKLRVKYQPRIQFLEEVSSDKPASDVDGEEANAEEEQGVAPMGSGELVEEATEETEVGDVESMEEDGLQQLVGVYFDPRVQQVIHDQCWPLAHQGGRTGASAEKPLPKVPEWQELEKERYFAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3C1</accession>
    <name>A0A8K1C3C1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphogluconolactonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3C1"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="39816" checksum="667849F642F84A19" modified="2022-08-03" version="1">MVLLYVGTYTQKLSFVHGKGKGIHSFHFDEATGALKPHGVTQDIGVNVSYITGTKSTIYAVNEAEEPQENDPHKLTGYVRALKIEADGSLTPLNRFESRGGAPCHLALSPGDKFLSVANYSGGNLSLFPIDQADGSLKPATSFYQASGASMANPDRQEAPHVHSTTWITAPTTGVVTLAAADLGNDRVIQLALDADKQTVTLLDNAPPTHRPAGSGPRHLALHPTLPVAYVVDELSSTVGVHPINESNALVPQDIQTISMLPADFKEFNLAADVHVTPNGRFLYAANRGHNSLACYRILVEDGGKLELLGYESTRGTFPRNFLIHGDWLLAANQDSDSIQVFKIDATTGQLTFTGHSVDCPTPVCLFLHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3K3</accession>
    <name>A0A8K1C3K3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3K3"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="812"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="865"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="892"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="934"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="55"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="107"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="159"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="214"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="369"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1001" mass="107667" checksum="748BEA1460AD3A8F" modified="2022-08-03" version="1">MSVVSTWGWGGNGQLGHGDRDSRIKPQAIKALAAREALERVVCGSRFTLALTTRGTVFAWGKNDYGQLGSGDTRAQIEPEQVEALRDVTIVSVAAKGSHVLALSADGRLYTWGRGDEGQLGHGDRVSHALPRVVSALAHQRVWLIAAGRSHSVAVTEDGAVYTWGSNEDGALGRPTGSDETSSATPTQVDTLYGVKVTQVECGSRHTVVLTSDKRVFSWGWGIYGQLGLGDATSRDIPTEVVAFRGKKVQKICCGFRHSFAVLPRRLMRSATSSSIAEMLSQSPDPSSPLVDVWGWGWNEHGQLGETTPTKSVLKPQKILALSNVDLHLLAAGGRHTICQLGVNDEVPILELTRGRSETDPRVRHRGSFQTLAWGRSSDGELGIGSVGSTFVPTGLPAFHNRKLLQLSCGWAHSAALSPESPFGREQSTSKWDLFAISKGDIDAFFGLLVQFIIQILLIFQILPMRCGLSTEAVTTKIIPAAAMTVTIGNTFFGFLAAILAQKEGRFDVTALPEGVNTVLVFAYALSVMAPEYDRTHSAERAWEVGLFAAFMTGLLQILCLPFVGLMRRCIPRAALLSSVAGVALAFLTMGFAFEVWENPMIALGPLMLVLVCLGAGVRLPFHIPTGVGALMLGTCSAFFLHAIGYPTSFTPFSEPYEFQVNFLQPDLSLIWRAMTNGEGWKYMSVIVPMVLVNVMSTLANLETAVAVGDNFDPTISILGDSITTIVGACLGNPFPTSVYIGQPIYKSMGARVNYVWLTAVAVTLVSLLNATTLIVNTVPISCGVGFLLWIGLVISASSFNRTPSSNTNHGTAVALGMVPALASWAFQLVQNAMTATWTASGASEKLPLRDVVRLLTTAGVNPSGMIALSQGYLLTSIFLASTMVNIIEREFLVASAWMGVAALLSAVGAVHSFEIDGDTVRGAFGFLPGGLESWSARYSIMYTAIALLLMLFHLQEGEISVAPVRRAFRAIGRRVRRAVEYIRKRGEEERQPLLATADKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C471</accession>
    <name>A0A8K1C471_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MABP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008766</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C471"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023341">
        <property type="entry name" value="MABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51498">
        <property type="entry name" value="MABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MABP" evidence="5">
        <location>
            <begin position="155"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="645"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="645"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1264" mass="139351" checksum="DF65A1B1987E5E6E" modified="2022-08-03" version="1">MTSMELTVVFAQQEYYVSAAVEPDKSISIELLQCQLMSILGLLPDEQILVTSQGDVVASPYASMALSSLSVDGNDRLRLFLFDAKEASNMESPVDWREICSRCVFGDTPVVQPAFRRIGSGDSPALICQACAQTCSSDSEMVTPLEWRASTQLPKRFISEIRVVAGEADVPVPAGGFEKVAGDLNYSASGDYVHLFVKRGGNRLITQLHVEHTSSQASTESSLANRVNVHCNAGNGSATGVFLGYQTASRFAPDALYTQAIADVRLCVGDEPVPSGYIKITRNLNEGAPGKAVSPLFLCYRLCPTGGFTCAMTHGAFGECLFQSRHASDNTVVASGTSPSRDAVAASLDEARQRADNTYFESFYRQNEPVMRRRLQGSLQRVGVYEDPQVQAEALKHIPVEKLHERAKANPTPWPSYQDELVMQLTHWFKREFFTWMNQPKCGSCGFNKTGLVHTEGPSTPEERAGDTSRVEVYQCPQCRNRTRFPRYNDPVKLLETRTGRCGEWANCFTLCCRAMGFEARYVLDVTDHVWTEVYSAHEQRWLHCDPCEDQLDCPLTYEVGWGKKLSYIFSFSHEEVVDTARRYTQDYDAMLGRRNDVSESWLAATIAAMNQTLLSALPADRRNILEARAVQEQAELTRGRVAKEGEVHGRVSGSDEWKSQRKEDGSHEADASQTSGATQEAKRATATRSKAEIAQMLCKNLLVGCDRSADCVNPYCLHQRARASPEMSPTDRAAQALQFVSSLQQAAFSAEGLSTLLCPVAGNVRDCVLHQKPRLYLPLQDGSDESSDLLVDCSGHEHHVTNPGCPLQKPFIIPSGDGKPERCAGLQLLGGQTLVIPLKSENTTPMAFSWLMRINGESHARKEQEILTISVASTLDLAVITAGDKLFRIVLRQNGSAVQWTSSFKLGMSYHVALTHSSEWRLVVNAKEEARLTRGEQLVGTTDVVFSGPKVVDSDQKILSPTPVITHFAVLPVESEQKLLQFCQTMKEKYVSAAPLQAIDHSGSPSDKTCELYVASLQSGFRVARVRMWGGEFFDGIQLVYEKESIDGSIEVVSGSLVGNRIAHRSANAPTTELTLLPNEYLTGLVGRKGAWMDCFRVETNFGRSLYCGGSGGNDFRVRVPAGSQIRAIAFDVGDHLADPVAFVAEAPGLNDDPTYAELKELLKNVDTSKCQAAISAACRYLENIASTPSDPKFQSVRATNKFFVTNIGNLAPATVTSFMAWCGFTNCEKRNEDDWYIFAVEKTNEQTAAKAYTRLYYLKQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4J3</accession>
    <name>A0A8K1C4J3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4J3"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="21738" checksum="AEF4B70EA4D4EEB4" modified="2022-08-03" version="1">MTVNEEIISENEKELAAFASAENAAISPVLTRVLEEIRQTGVPYYQWPHLRALLVARLKVALDETQAADKSGAVTVGWSPTNKEKYEERRQQVAEQLTAFDGPPFTLQRLTEVILEPHKSYKNLNKLFNALEKLLSVTSTIPVADPRRQDEPVVDENEPPAAITVSVSPVSPAPAPQVVAGAVDGDVVAKAPWSTGEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5L1</accession>
    <name>A0A8K1C5L1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal biogenesis factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5L1"/>
    <dbReference type="OrthoDB" id="45930at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="45258" checksum="FCB8707DB7798B3B" modified="2022-08-03" version="1">MWSALEHATARVCGFVRRHKKLVVATGVASLCVGGVYYGYKRMVTEAERFGLQLQRQMAEHQRLQLSLASTTEESNATIQRFLPRLKKTLYQLVDLESIVQELKTLDKAQKPKRIQLWEQAKLTAVTRYFTALIAFGLWHLLVFAQIAIIGKRTFEKNKNEWESTRREADEHQALAAQHAFLASGLEYFLTDGIARIQKHVESVVAANEQLQTWEVSRKLKVERDELNELLQSIYLSIIPTDGTQSAEVEALWRSFLIYPDKRDDQDEHVISLLNDLWDLLETDLFGPALQDSLGFLCGNAFQDLNEVVYGCTSRRFVETEEELRAQGQQQKASPALAKLIPALQTEVNKLLTNSGPESYLVKYSQGVGEMERFRNFYEAIFFMQEEDEAVMQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5W4</accession>
    <name>A0A8K1C5W4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5W4"/>
    <dbReference type="OrthoDB" id="1918363at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="921" mass="103706" checksum="AB48063DCAD74A95" modified="2022-08-03" version="1">MAGKDVDFRALYQNSLKLTTAIDDFGIPRLEKSLDQLDDASRSFFHQQPQPTATLKKKRPASSSAKVAVDKANFLLAAKGIDAEKLSKELQAFELTSGFEPETPLGETDIEGYLTHHHEMIILTAIEDVNRRTMEATHDRMNQAMIDDFELAKQQLLEELGSSKQLGVRNYPRIVENLNDSNVFAARNDDQREQQVRGFGISGASFNGQPRFDVSQSGSFFSPDGSVSRNEGPLNLSQLGVDNQLSEEMKLYYSVIRDLNGSRIPGARTQFDVVGSFQRICADNVSASTVGSKWEAVLKCWQVVNNMLAGGDVKNRSRVISEREFASLYEQDEAQRMLVEQRFAYGARVFLENQFRGFVQQTVQKNHLPTGGIPDLVSSVRAFVKYMQSASGISTTDNDVDIWALLYYCVRCGGEQEAIDLATSYMRAGNSPIDENVLCGLRYRAHQTRAIGERGGAPLNVFSKQFPAEYSRLVDRYHRLTSSSIDAVAVVNPYERCVINILCFGNPNASEPRIMTTIEDYLWQRLCFIQRVAPSTAAPDSAYTIARLAKSIHKFGPSHFEGSKATGSNAYSPFLFFEILLIAQDFEAAIKYIGSRGFLLEAAHFAIALNHYGLLRCSPFPSNEEDEYSVDFIRLVRQYVHGFQRTNPCEAAEYIACISDVAAKKELFSDLLLETRKFDVLAGFTNNTDGSRTRGLYDRLLKDVSEDEIRELILNAARKAEAHGRPHDAYALLKCAGDIEGTISLLNVQLSSTLSAPRPEREEWFRVAKEFAEKWMRFPWVQSVANKYARSGAVAFQTLLNINIFLEIYERQQYDDAIRFVDELEVIPTPSANNLAVCVDRFLAFDETVRQNFHVLLLGYVECLVRDMERLKVQTTGEVRRVSVQTLREKAELVVTFAGMVKFRLPSGTNERLNRMEAMIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5X8</accession>
    <name>A0A8K1C5X8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5X8"/>
    <dbReference type="OrthoDB" id="64281at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480247" description="DUF7492 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="18"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="409" mass="41258" checksum="58CF8357D99D5B31" modified="2022-08-03" version="1">MRLTKYTAAALIAVAQFVDAHTWIDCLDTDMNVVLQKWKEQGACKGYIKNYTGRASNEVDIKSTVKTDMMEVSKGGKVCDAGPGNYVDWRHRLQVQPGQPFYFGYLENGHVSKDESGRGTYYGTFWTGQPNTVLEKTSDMTPDKLVDGFFHDYDDTRCGESTNMNGQPSGRAGDGVPCIGKLAIPAGTAPGIYTLVWYWRYFKNVGGVPQKITNEKGTFGGSAYASCYEVEVLGPGGASVAAPAPAPAAGLPAQNGTAPAPGIVQTSPVAVTPSAAPTMATIAPAATLAPQVASPTAAPALDTALAPSAVGTVPAATTTVGTTPAAATTTAVGTGPVAEPVPAAVGDALDPASGQATGTSPTGPGAASAAVLSPAQGAGVIPQSAVTGVATGAASPVAALGVTPGTIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Z0</accession>
    <name>A0A8K1C5Z0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Z0"/>
    <dbReference type="OrthoDB" id="116195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="31695" checksum="BD3B5117F0DE880B" modified="2022-08-03" version="1">MVKPLNKEWELFGRKYRVPGAKGEKVDCNACHKQVSAAVNRLQSHLRVCPARPPLPVSLAAQIHGAHSGSASDLDDGGAGAAGLVDGTDAMGDATDLGDPSLDHSSALGVATAGMLAGTPGTAVTTTAHGLPMAKRQKTSPSRSRDRLRWNTAVDDFWLMNASPPPTAAYAKKRLDIEEKRLQLELKRDQREERRERLQLEVLEAQARKERLAAEKEAYEARVLLALSRKQLRDQGVSDEEIDRVLPIEPLGGTASGVDGADATSEADAGDENSHAAHTMSNTLVDEKNATETNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6A2</accession>
    <name>A0A8K1C6A2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6A2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="665"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="750" mass="81670" checksum="B8A53CE40EC8985B" modified="2022-08-03" version="1">MRSAQYSTPVLPSFVECAGHTESRRAKLRAHSDPVHPKDYPGYSASSDTASQRIQSQSGVNGTVILHSNRFQLRKRWRWWQTELTLIERDNQTKELWYYDGPRRKGLVLTQSMDNPVRIQVHVMNREVILTASKRSNRVEHAATPSTPNSQYYAVIEALTQRPMMSSDNNDEGWTAKMETLVSILKIGLYHATIREFEMDHNDEAQEVVLFCPEKRSLRLDDSSSQAEYRCMLKAQLRNIAQSPSGVDDAIETSVAGDDETLKSMVKLLQVPLFGIISSPFDDDSTAIDQDAALVVHEPVRVVDFDGSVHVTTTMTVFAMRQRFERHSHSHSHALTDGDSVHTMLSTGAKQSVTELRALFGEAAAWRHAVQRPIVQEAPVAQAALVPQVHQGAQAQVVHLACVDATQWQEAVAHLGARLVDHAPLALAAQASHVAHVAAHVDATEWVVVQDHIELGAFEDVQAADPSHVGDDLASALALAASLTRASDGQVACFASVPQDCEDAEVVVAAHVGARVDATATATAGVAEATEATEVTEDIQVAVDEATDVDMDVVHEDAQDTQDVAHLGARPIDTTDVEDVVEAAAITRVGLAIQDPSHVGDDQVSVGMQERVRRRRIPPPTTISPHFRPRSRINEASSSVPLTPRTSLPALQARQVTPTPSAMCASTKSTATSKSKSQSKMTTTSTKTKRASPPSSPLHISADYSGVAGKAIKYELLGSYQRRLYDSRARRCQLQHGATMTALTATRCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Z7</accession>
    <name>A0A8K1C6Z7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Z7"/>
    <dbReference type="OrthoDB" id="436841at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06705">
        <property type="entry name" value="SF-assemblin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01799">
        <property type="entry name" value="SFASSEMBLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="353"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="574" mass="65704" checksum="5F1A29C8DB61034D" modified="2022-08-03" version="1">MEKRRRWTIRVALDDAELRAKDSLFVEMCELLMRRVDAAAARVKTAVVLVQATGEHHFNALEQLSRLCFEHRIWNGVFQPLVNQGKQMVAYVPRYSSSGSVQREIERLGSTVGLTVATQVETFDDVPMLVIDTLVQALLFQEIQGHGAMVFGDAAVRQIVFADLNQTTEVPTVAISHPQWHIDPYRRSIQITMTCVPATMALTTLAMNSTDLAGSHIADNGMCESRIQVLPGMTECFVVSRHDDPPAPTHLLRASWCTGLQRYVPTSEQEFRDYWSNVHGIDLPEDIGGFVRATMNQQETAEELTPSHDAPMETEDALAAQLGATATKSKLEKLMHDFSTFDDVMRIGTRQRRERDEYRLAEMKEEMSRLEKKLEAEVRKRVEMNKSLQNYCDEQVTSMIQRFQELLDARAKQVSDRLDGLATEIQQVQALVDQEKREIPLMIERKTNELTQKLVAFMDAFDQERLRRMAQEEMILKRLSDHEHATAEAFDRERRDRETKYAELKSALDAYTTTRNRGDERFQAFVQSHVARIQNGLVTEAQAREREDDEIIEALNRYTAKLQDSLQIITRPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C703</accession>
    <name>A0A8K1C703_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C703"/>
    <dbReference type="OrthoDB" id="163096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="215" mass="24237" checksum="A3E8CEF2CC91DF28" modified="2022-08-03" version="1">MGKRTATEANMDSDDHGFWLETPTFYLPQRLTTQSPPFPQWNFGGRSNHPCVEPAAAHARVRPLPKLFTAIEQPTKTFVTSVPNSQDERATQFTQSTAPTPIFAPTPRRGVSPDLIFQSAKESLIRNQRVETQDENDRMRTNLAELSRRQSFRPIAAGRSDIEVTSPPARATNPVIMDTRFQSMQRLDLKLDARNAPFQPFCPRARRHAPIMGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7E8</accession>
    <name>A0A8K1C7E8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7E8"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="103"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="54754" checksum="08AF85321C05A690" modified="2022-08-03" version="1">MSDASYTRCDMGLFDFFRRSSRSDSQRSGPTLTSMASMPVTSSSDAADSAALQERNSLPARPAAYQKQTSTSMDSATTTVSTESNNEEGEESRPESLGSIQNYDIVRELGRGATAVVQLGKRKNGNELVALKVFKTSLLKKMREVKRVGRKMVVSTALDKVQVEIAIMKKLQHRNLLNLLEVFDDDSETLVLMLEYAPHGQIMHWNAEERVYHASPMVLGLSETSADDGANPRVFDEELLRKCVRQLLLGLEYLHENNICHRDLKPENILVSDDGVFKIADFGVAHLFEEEKTTPDAATLKKGYVSSTAGTYAFMGPETLKGQAFSAYAADVWALGITIHALAFGTIPYYHSEVVELFDMIENEPLTLENNNITVSDGLTALLQGMLEKDPEKRWTIQQCKEDEWVLQGLDAEAVKSFLNVKNEQVQVSEEEVARAVTRVTSFSTLMRVKLTANMWKRKTQEAKRRASIETIVEGVDSTPASTKSEDNQADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8G2</accession>
    <name>A0A8K1C8G2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8G2"/>
    <dbReference type="OrthoDB" id="148089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="379" mass="43707" checksum="CBAF6D9E11C49B28" modified="2022-08-03" version="1">MSGSSSPENDSLPALSPLTAPLSEKERQERQRLHMRRTYYRKMNRLQALRDQVQELKNQYEDMLDQYRLQEACALIADVPYNQDEGMRTLYTDISEVKERLLQQNEAMQAALEGYKKFTSQLRRFVTPSPHADVFGPSQFVVLLKDAVSSTSHDASFVVPRLRAPLTLEFCERMAKQTYLDMGSFLKSTIFQSTGMSVYGWRDKRHLDGEWVKFDLKKTFHNLSVDDIAFRGWDFLSSPKKTQQLYSASMIPRVYGVQRIDDRNSVLLRVFTSPDGLSLVKFFFLTSLFETPTGYCVILRWLDHNLLVPPKHEPLLQEFWMDCYGWVTFDRAGDADEHSKIAFGGDIHSSLGVGPDAWMLEALFLALRWETHVVGSIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C931</accession>
    <name>A0A8K1C931_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature viability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C931"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="61486" checksum="E86A677CD2AF6524" modified="2022-08-03" version="1">MGKKKPFINKKTAQHFHVVHRSQRDPKANDPDASKYVLLSANKPMELASDSEDDDEDDDDEDLSDDDMPDLIDSPKASAARAPAARGPVKKKSKAAFPTRRVRFGEIEAEDMVDELGIVRDGYDYSQHLKEMGKGRFYSAGGEFQNHNAMAQRVELPDDVLPSAEEQDRLLEAITLTTETMDDDLREALVNNDAFEELDDDFMAQAAAEDPDDNAADGFDYDAHIAKLMAAASGVPKFKGNLTDSEDEEFDSDEDDEDDFSDLEGIDRTEHQRALDDAFEKLMAEEYDDDQLGELEDDDPDTRGDVVLEGALLESIVEDFVNVRQEMLNDEGKLGNPMRSGNRLKEILEECERERALEEGETEEEEEPTVEEDPQVEQDLRDMFERNAYLAPRERETWDVETIVSTYSNLDNHPTVLREDTSMLKKKKKKKVLPSVDEDTLAAAARNKSQILLSSKTGMPLGIFESTPKQKERAAKTEAPEGPVAPKKKSAESKEEKKARKEAVKQQKQQRRQEKKEFKTAFKQEEQRQLSQTQAGKVSVFKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9J0</accession>
    <name>A0A8K1C9J0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9J0"/>
    <dbReference type="OrthoDB" id="164098at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="30516" checksum="0136B86C97A2545C" modified="2022-08-03" version="1">MSPLIASAQLVLHSQRIHEDAIIHLVARFAFPPPNLFRAFVNQPEASALRAVRWFHEWHPEPDGYIMEMAARYDQFAVVRFLHEHRKDSCSAGAVKEAARHGNLEMARYLIERVNAPFTKSVLSAAATYGHLHVLQYFLEHVPSLRDKWTHKVVVRAARYNHLDILQWLLEHQLGVITFEAVQTALNMGHTQVFQYLLMNSDVECPSRSMDVAAREGDLALARYLHEVRGIRCTSDDLIESANHGQVDVARYLHEHLTEQCTPDAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9P4</accession>
    <name>A0A8K1C9P4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76445at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="1311"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="789"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1063"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="706"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1107"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1346" mass="147856" checksum="703685EBA94B2204" modified="2022-08-03" version="1">MEELWDSEVARAGSWLRSRRRQRAELQTSIFERINNHVLYLDHQRGFQENHDGDGENGSDSGGDSGSDKTAEQEELTLDFLGEIDPDDMRTLLDANTSDETVVPPESAPVTLASMEPLQMPLHLISEVNPSHARAREALRQSATPAPSPPPIVTTNPTAFSRISVGVSLGEDDSVSELMDTLQIDASTLHQSKEDGEESKTEESTPPLHVRLQQAGFKQATSNGSEDMPPKQPAKTKEAALDPNSVAAEMFSWVDGERHPDVIKRKESLRQRRQQPTLFGSNTYSDKSLKRHAAKLFARESDGSSDDLSPNDSDFSAGEVDGEDEPEEPCSDTELLPDDYLDESRMPQKARRRIRQRKEPKQKRRRKSSQAVIPVSSRHNSPQQHRKRRRSLHESDGEGDGGTSTGQVRPPPPKPATPAPSVTIDLRSEDEDSDYNPALSDRDETETRNNSLVRRFELSKPSVGISKRVEQAKAKDHEKSAAVIESEGVDQSGSIDVDMTSDHDVGGYELGDQGDRDGCQVATTTAGLHEADSIPPNALESDVSANPCSVPEKEDGGEISDTGTADFEMEASDDSADEGQKHPHETDLPRVNASSPPLSQGPEEGARQSRTDGEVSPPAKVVHESRTMQPMDPTLKTSPQRGSLSSPVLEDKSATSPQQSQSNVDAEEDEEVNAVPDGEDDVSETDTVVFDDLSEVDSESSDQEEGTSAQPAESITEPQEASSNISAEPAESIVEAPVESSKADSEDEAFGQFFSSAKPGTKEVVAAKQTITLAPFGTVVVKESVIADTVTAPEKTSTAAEKTTDETPEVAASPGKTATGSNGLRKVPRKVPPVNTMTVTKGKYSYKRAAIRMLDENGDVMADESQHPKHKLTARSRLLHHEPPLVGPSLLETHAISPLQLRKTLAASDREDRLNSTTPEQQDKKRYLGYQSTAKPATTASLVTRPNGLRQSKAELFARYAKNARSKYDKTGGLETPLEASRSLETTGAFLSETTALSGGMLQPKDTQMMTPTTNKTSLYMPPRERQLNIYQVTGAISQVESPSNTALGLGSHKRPTTYVKQVDEAKRNGTHVKKGLAPELDPRAPIPKKAKTSHEQAKPNGKPVSQAPSVSDEQQTQFKNKKKKRGKCKDFEDGFISESDDGEIELIDDEDDWKRRDIRYPLRDVPIDHSLMERMIYLTHLPIKFDEVMLEEVMYGRGVATDPETGFAAIHVFMNPLSQIPRGDARVVFESSEAAAHAVQEINGKTHLGVRLVARPMDTNTMRILHAHFDIHRDTWECANDRCRRQVSVWTARCDGCGRRRVFSIRKQVEKADWLCSICFSTNDQHASKCFGCNVAVPDQPRHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9X9</accession>
    <name>A0A8K1C9X9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C-factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007130</name>
        <name evidence="5" type="ORF">Poli38472_007131</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9X9"/>
    <dbReference type="OrthoDB" id="68267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="24737" checksum="91F40DB88B13360F" modified="2022-08-03" version="1">MAGNTNTNTVIITGSNRGIGLALAAEYHAAGWNVIAAARNPSTATELHALNVYKTIQLDVADEASILRAAQDLSGEAIDLVINNAGILHNNTFLTETKAHLAHTYEVNVIGPFLVSRAFLPHLKAAVANKGSAKLIQISSTVGSIALNNGGWGTPNYRASKSALNQLNMLITHEIKNDNIATAVLCPGYVDTTLNGNTGVLKTSESAAAVVKVIAKVTLAETGKFFSHEGKELPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAJ1</accession>
    <name>A0A8K1CAJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAJ1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="490"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="854" mass="96418" checksum="392AA2ED8F7C9E39" modified="2022-08-03" version="1">MGQHTPAETSEAMRFHGETVLDASLAFLDELDKLPELPDMSNGSEMALIDPTESMLSELLGLTDADDASIGIPDPPLTEVVVPAQTASDGASKARKRNSKPVRKETNAVRKQEIKFLRAQVHELEGELSRLQKSVTPVAETTLWEGIAMRQRDAKKRVEAKNAKLRQLYQGQLKVARGLVRLLHKGENDMSSELGNAKRPRLIVQGTNTEAIFQSIRFSLATRPLEVDEWMHDNGLVHIRDYYDDSRVRRGVNNDIFLEMVLCRRFPFSFDATAEAVWGRFCADHLEMENGIYGAVERSDTHFLARSKVGLKLHRLESSMEFYAAGQRLNENNRMVVSVELRSIMSSTNDRGKKECLDEVAYMVIERDPLCPSQSTIVRSCKRSWPKIDKMDDEEASRSNFELLAAMIIDICNVDVAMGQQAPVASSEAMRFHGEGVLDAPLAFLDEMEKLPELPDPVNGSEAVLIDPTEEMLSDLLGMTDADQVVSCIPEPSRTDGAVTTANSTEQTSKNRKKGSRSVRMDTKAVRRQEIEFLRAQVQELEGELSRLQKTVVPSTETTLWEDIAQRQRDARKRVQVENTRLRRLYEGQLKVARGLVKLLHKGQTDMSSELGNAGRPRIIEMSDSADAIFQSIHASLATRPLEVDKWMDESGLARLRDRFDDAHVRRGVHNDIFLEIVLCRRFPFSFEVTTEAVWNCFCADHLELDNGVYGAVERSDTHLFARSKMGVKLHRLDSSLEFYAVGQRLNEANRVVVRTEFRSVMNDAAVQGKKECLDETCYLVIERDPLSPLQSTMVRSCKRSWPKPDEEDREQVCRSHFELLAAMVIDICNGNCQAMFQHVENHLVESTLPSYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAL0</accession>
    <name>A0A8K1CAL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAL0"/>
    <dbReference type="OrthoDB" id="64619at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="50159" checksum="B4F79241D59930D8" modified="2022-08-03" version="1">MASNDDTFRVNADAGDLLFDAEAQEGTLLAALAFVDEFECDPLSNALVGVDDDLEFLSSLDLDSVTSTDETASYSIATPSTSTNESPAPAKPAQPRRTRTNRREELIYLRSTVEEMETKLTELKEQAKEKDERTPDLSDVMKAVWEDLANRQYQQRQQAEAENTRLRMMLEDQIKIAKSLERLLRKRNDVELFSSALSKKRSRAQLGQSPLREDSIVDELMGSLLQMHPHVDRVLEDPRFHVDAPKPLRDIQLRTAVGFAPTIEIVESRIVPFNFMVTANAMWELLATNMQDSITEHIHTATEDTLIKSFEGVVQTHRTKGVFQGKVVARRFVEADRVVMLGGHVAEPVEFSDRPIRGVIMRHRGWTVIRRGPNDTTLLQTYHLAAPDVYDASQDQQRTVGALTNFVLATVEMNLDAGLLQIENYLLETQKHHDQDSRTMLADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAW9</accession>
    <name>A0A8K1CAW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAW9"/>
    <dbReference type="OrthoDB" id="193300at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051493">
        <property type="term" value="P:regulation of cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000059">
        <property type="entry name" value="RIKEN cDNA 6430531B16 gene"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052111">
        <property type="entry name" value="Spermatogenesis_Ciliary_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509:SF9">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CH-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="42915" checksum="069C23961355064D" modified="2022-08-03" version="1">MHGLYEWLDGFVFSRAWKHPARDFSDAVLVAELLAQLRPTWVQVHNYPSTGRFQQKLINWEMLNRRVLARMHCEISSKHQEDLANAVSGAIELLLIRIKKQVDRENSQSPRKNVSPTPSPRKTESQHHEGHSSPLKGGHSPSKWTFSPPPMLSLKSSSPSVSPSKLHDRPQIPPPPPVLFRDALPSSRDRPSLDHLASTFAMVMKVSDERRHGVARTIRSKKVQPRQNALTLGAKTLKSRSLAKQTALSMCNSQDSFVSSARQIESKYRAARHLVEYRRVWPRNLARGSPADAFVTHRAEAIQRTQADLAAPVSGAFDRESDVRSEIQSPTNRVQEPVEFEAIATPSVFAPIALDFRLVLETLPPKYPSQRKARHSLSDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBA3</accession>
    <name>A0A8K1CBA3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBA3"/>
    <dbReference type="OrthoDB" id="422779at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="555" mass="62026" checksum="B5ED56B79A369C87" modified="2022-08-03" version="1">MSAKPSILDRVSYVSSTANDKDKDLEDGYIGAVTPTVEGGALRAGETPHLLSKQTLGLLAQYAAVGMVYGSLPYTIYPFLTAYLNMEGTATTSATALLSIPWSLKVFIGMLSDNFPIFGYRRRPFMVFGWTMCSICLFVMAFMPMPKPYFIKPEYRDLDVSELIDGVTVREDSPDKGAKYIILMMLASLGYVIADVASDAVVVEYAQREPEEIRGRTQTAIYTVRTVFMTVAAATMAFGLNGKEYGGDWDRTMSFSNYMLVLAIFCIPAIFMTWIFVHEEKVAKPNFKQYISTLWEAIQSRAFYQVIAFNFFFNLFSNQSYVSLNPIQNYWVKATNLNYNISNVIGNLVFAAMLAVTGKVGLAWNWRWMIGTTAVIMVIIDAIFTMITVWDVFRNQWFWLGGPIVEQVPYGVQFIISTYVVVELAGYGNEGACYGLLTTVSNLSQPFANTITKNIDGGFDVWNKDIISDTDHVRSQVTITIWIAYACKLFALVFLVLLPSQKKAVQELKLNGGSNKYIGAITVFYCMFALVWSIMTNLLGIFKSTKCLSIVGGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM4</accession>
    <name>A0A8K1CCM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCM4"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419612" description="GOLD domain-containing protein" evidence="10">
        <location>
            <begin position="23"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="27944" checksum="343F6F769A52FD9A" modified="2022-08-03" version="1">MLRRSLLLGTALLGALMVHVSAFIVEVPGRSQECFYEYVRTKRTAYLKIGVLESLDQYDIRLKAYGPFSEHPDESETSMGFFDQMVTTERDETSNNVQHNGFNFDSEHRGGWYKFCLDNTHSSSHGKKVEFYTKFDLTDESEKGLEDELEEYARKEHIEGVTKSLGRLKTLLDLIKNEQDYYRVREHRHSMTQNSNNSRILWYTTFEIMTLGIMYAAQSFILHKWFSDRGFLQTRQWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD25</accession>
    <name>A0A8K1CD25_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lariat debranching enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD25"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="1">
        <location>
            <begin position="246"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="44994" checksum="08D16113EEA0A25C" modified="2022-08-03" version="1">MRVAVVGCTHGALDAIYEHVTQINASTTNEHEQIQLILCCGDFESLRNPHDLTCKACPPKYRHMNTFPEYYRGEKRAPILTVFIGGNHEASNYLRELYYGGWVAPNIFYLGVAGVINVGGLRIAGLSGIYGRRRYHHGFFEREPYDDKMLKSIYCVRELNVFQLGLLKPSNRLDAILSHDWPRGIERHGDLGGLLAVRPDFQTSIDVDRFGNPGGEMLLSKLQPANWLAGHMHVHFEATVVHADGEDASTTDDQVSTRFLGLDKCSSNGACVEIVDFETPASVQTEDLRIMMDEEWLAVLRKTHHLLSTTRHKIRLPREPVEITDEDLAWVRSRVEEKTGRGECDSKLKGEWPTDFVRTAPALGDVDENEVRLNMGNPQTDAFLDLLELPHIVTVPYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDD2</accession>
    <name>A0A8K1CDD2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDD2"/>
    <dbReference type="OrthoDB" id="166440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480172" evidence="1">
        <location>
            <begin position="17"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34305" checksum="B401D71478549484" modified="2022-08-03" version="1">MMVCHGIFILVVSVFSSGVFWTFPDIPLDCIHRVYPRFSKAEACGGRIINCTHAGISGNKSEFTAVLELFDDASLEFLIVLDCSNLQLPSTIQRFHQLNTLKITDATLSEWNEDASLSTDAFPVIMTLRLWNITLECSPYGLYRVPVSSSLEWFSFENIDLSGFIGEVGSNWKDLQYVYFDATHIDQVPEAVATMSKALELSLRFNAISVVNGSRLTSLNQLTGLWFDGNPITALPDEAWRHSTHLQEFGFQYTSVATYPSWANSVTNKELQFNGFDSPLCDPSNKAYAVGKLDYLACIENFYGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CED0</accession>
    <name>A0A8K1CED0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_010944</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CED0"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000129">
        <property type="entry name" value="Major Facilitator Superfamily (MFS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="29"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW61881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="512" mass="55582" checksum="A206D71EAE5FEA43" modified="2022-08-03" version="1">MAGGVVIDTMQHNFDDAPTEGTRTYAIIVCIFASLGGLFFGYDQGVTGGVLVMDSFINDFCTGWKGFTYEDCTKSSANLPNAWLDFTLWYNMAYNIGCIFGALLGGWVADKFGRRVTIFTAGVLFCVGTTWVVANPAGKHGLLLAARVIQGMGVGNSSFSLPIFGAEMAPKELRGFLSGFMQMTIVTGLFLANVVNIIVEDYSHGWRTTNGVAMAAPIIVMAGIFFVPESPRWTYVHKGKDAAEAVLKRLRQTENVGRELKAIGDQIAEEGQQVSWKDLLEPSIFRRVIIAMFLQVLQQATGINPIMSYGGMIFKDVAGDGIMSILFLSLVNFLSTIPAMRWVDTTGRRKLLLIGAVGMIIGHLISAITFTASCDGNTDNSGCGKAPGIVIVVGACFFVFNFAISWGPVCWIYPAEIFPLNVRAKAVSLSTMANWIMGVVMTYVVKLFPHLNINGVFFLFAGTCCICGVYVFYMCPETKGMLLEDIEQLFHKGGATMSPKYVEVETPAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEJ2</accession>
    <name>A0A8K1CEJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEJ2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="48740" checksum="836D7A381D053787" modified="2022-08-03" version="1">MSVMNHGALRKPSIPKLSLTPAEQHAVENEAAALLTQTLQIEHDFFVNDGVVDEQHWKHLKSSDNFSIYKERYTATESSQDDSTSWKSSDSFGPNMRSASIDSDDILSNKKNARVPLIVSTGHVEGSVEDVVFGFAAPDSQSWRFRSAYTKDQFADSKILATIHEPSEERPFNYLCIKWFVTMFPAILQIFVDPRDSLIIEACGVKVDEHGQRYGYHIIHSYEHPAIVSMEASGICRSSVSMCFIIREVRPGKVHVFSRGFVDPKGDMSPNVVVMFASKAVLTTAKTVEVSFAKKLVWLMAEQERERQDSRRRGRVDSSEMIDSEACVSCGKTPGFLNAKLATCRLCREKFCSKCTSQHRVVVDVTRKEVTERTFPFCVRCVFKAKQMSPHVVAVEKARQNANRVDSSASSSQRSASSTGLDSQRSLTSDPGLSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEJ6</accession>
    <name>A0A8K1CEJ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEJ6"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF2">
        <property type="entry name" value="SLC26A_SULP TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="511"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="723"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="771"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="894" mass="97702" checksum="D35C0B5F2A45D966" modified="2022-08-03" version="1">MDAASGRPRLDDTHVILQSPAHGLRVPKPAAKMDKPCLVSTKMLVESGIQAVVTGMIIAVVLCPVMIGFVTMIYGHQEFEPVMAVLTKIIFLSSVAHQLAITFLSPLPFAIAQTQDAGLIFLSTMAASIMNQLGVAVPLEERIATVVVHLSICTALVGLGLIVLGKLRLASRVQYLPTPVIGGYLAFIGFFMVKGGISLMTGTNLTGFSSWGQLFTTHQMALLLPGVVCGFALSLITARYQHFAVFPACILLMPVGFFVALWMTGTSIEEARAYGFLSPATAPIAITDVYGLFDFSNIHWSVMFPSQLPTLFGMFIVVAFAASLDIASICMGTGCTMDYNEQLQTVGASNLFSGLTGGYTGSYIFSQTVFSFRFHPAAIEKHHPGFSRLIGFSLAACEFAIVLVPFSLTSIIPKFLFGSVMIFIGIELLKTWMIGVYAKLLTVEYVTVVATFIFLNAFGVQLGLAAGVGLAALCFLVEYSRSQTVTLVQKSSNVVRNADQHELLYGSSTARQGSLMKNQPIVTVELQGHIFFGSATRIQKRVKRAVYVYPEQTTQSERSDQRDERLPLLSTSSLVNLEGTPCTDRHRGPTRFVVIDFSHVSGLDATAARSCFLALKMLFKRHKITVVYCGMKENIEFLLRANDVFPAEDHDGELCHITSDADLALDWCEQQLILAAAKRRSLNSGRSLQAFLPSATQELSLPLVFNAYLSTERRNTPAVTQAIEDVVQQFTIQKWKPNDRIFMVGEAAESWFVLLRGQVTLYTTSATSVATGSPHFGSPSVSNLRQRRYGSNGQHQPHSQDRSSSSSDASDGSDRELVSRVRAGCIFGDMDFMLQQGRSIDAVCTEENTVTAVISRSKMEKLLQTQPQVAFVLQEVILRASYMTLAEKLHSIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEM6</accession>
    <name>A0A8K1CEM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEM6"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="97" mass="11175" checksum="74F73A9ACC5EF942" modified="2022-08-03" version="1">MMARHSGLQLQVLALFKTALRVAKQKDQALLKEGAEAVTQSYRSGGTYRFVRERFRDDAFSVDRMNFAVIEHLLRKGQRDLKMLEQMKTASFANVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF58</accession>
    <name>A0A8K1CF58_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF58"/>
    <dbReference type="OrthoDB" id="543798at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47581" checksum="780CE785DCB2FD43" modified="2022-08-03" version="1">MQLFMEEEPVHAVLTDVYLLHHVISFQRGIPGRIVELERQNPDRMNIVGILPQLAIEKNDLKALQTLFKVCEEFPWYRPMRKMDFAQAMHVAAKCGRLELLQWLDANTELECQPWTFAAASRAGHLEVVQWLFEHRRESMAKFEPFSMDRVAEEGHIEMFQWLEEHVGVPCTTSAMDSAAFSGRLPMLRYLHEHRAEGCTPLAMDMAAIRGHLDVLQFLHENRQEGGTTWGMDSAAAYGRLDVLRFLHEHRTEGCTVKAMNDAATWGRFEIVKFLHENRREGCDKYAIRGASRNGHLEIVKFLHKHYHKHCSRDAMMAAAEDGRMEVVQFLNENCSSANGMAITSAAANGHLDIVKYLVESRTDGCLLAARDKAKKLGHDDVVEYLETLLAPDVTECGNNNHGRNDTRRACQRVEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF78</accession>
    <name>A0A8K1CF78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_009603</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1408"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1550"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1748"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1790"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1921"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1990"/>
            <end position="2012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2135"/>
            <end position="2160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1598"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1755"/>
            <end position="1766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1798"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1828"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1921"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1994"/>
            <end position="2003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2481" mass="274828" checksum="9591A7F382AD67B6" modified="2022-08-03" version="1">MQFFKQLTDPALKRLYKFVLKRLIGRFLAEDEIDLDQLDVHLRSGRLELCDLLLNAEVLNREVCEANGLPFRVKKGYLGSVRVTISYTNILSESCLVEIDDIEVILVPVSADGDNDNDKNWKEEGTSVGGLNAATKASLDGINESKQAEEDTQDHMDEVSQEGLDFVASWIEQVTSKIKVTLSNICLRLETGQSEESDKNVAMLFKLDWAQFTDESASEVASVYGRAGNIDQSFGGAQSMYQSMAASSLFGISQKGIKFRGISMDLSVPGEESEGADDPVIYPFLASDSTRQCYVQLKVSHYEALEAPSIDADLFLHSIRVVLQPQHFPQFGTLMDAFGEEPGAHSRSRTDDPYHVTSMYQSVCDAQPKWLHEEETEQATDADGALKLSFREFQRIEQLLKHYHQTHQDLRSMAQRAASGSNADDDVPFPMPRRLSMADSVESVGLSDLDEEDNFFECETGAESVSGNVHFGASSVMAQSMYASALYDAEDIQQNTTGQAATSSLRSSVKGKSASRSVRNRVKLHLLECDIILLYDDMLDYDEEEETYDGYSPRQRKLHERSRRHLPTITDQERLEVCIKDIIFSTLVYPSHISMSFSVGTLEIVEKTLARLSTEIVEDEHSMITTSILKFVDYSPATGRKVHLSANLSAQIRIDLTNDDEPKTESMAVQISAQPILFEWDMYILDRAHRLMKLLEDSSAAKAKKAALAGPQSPPLPVFPKKLDVNSECIEITLRFPMVASDLIRFGPSSKRGLSEDKFVLTLEGVKVSSYADDPEQIDLSEKEALPWLSDIRIRFDNAVISLIGPKGGNQRAKDLHKTVIITATSDNTSGDACELRLRTQTPTTEQIRAAATAKHSMSQDSLENLDTTSVGMIEEEKSGDDNDGGRIGSNGWSQDARARAHKFEVTAAAAALFDLEITIPQSLIVFNKESFDRLMILFDALMMINPIDINGHNQMMMTPAYRNRLIPSYMTVKVTLVDGTLQLQYSKPGTQKNGAEDSTTMSAPSSIYHLAFQDFKIFQVSQWMGQLVSRVHISGDNLTLLEELCEFNEVYPVLYKNPIGVNEAPIVFIGIDIVDQTQEMREMKVDLHFSQVNWRYQVASKWMLELAELLLLEYPLPIIPLDSPSMDEAEFTAMMTRVDLDTYEPVRLAIPPKTIFTKLFVSLYDAVLDYTPTTLTSRVMLVLGNVGVSSNVVTGAMIQGYKISVRDVQLYLTPDAPSYAEMDERLLGNELFLNPQARKKKKGVGFEKERSRGQLAPLYPSMLMFFEKHGFLQMVTLDFIDVFLRAIVVAEPSGKPGSTDIEHKPSTLGSPELSVELTLGTANIYACFDSFNTLIELVSTWGEQLSEEAEPRDTTAYVGLDRVKDLSSVSVVTNLGPSRKRAVGTLSEDTSSVVASVSVDASTRGRSIRSGLHGRSEQGSASSVVSADTAVPTRNHGIDILAQIDENAFGSGKGIFPGKHVATDTEARLLRTRLDEIHKEKTRIVTGEGLRDDMLSATDLRRKYKDTDQNRPRMRINELVIEDYYDGTRLRSASGQLSDAGAFLMADETAESAPPAVENNPWFASSPPDRPAFPGDQHPIGSLPDEQAARWLPPSGFMQNQNFAGTPSATSSPRFDPVDEDAGSAVSEGAVVDELSSLHDLLLQDRGEDDDSEDDDYPSAAFPAASKNWWGLENRPDVELSELQTDTDSMFSHQLPFPDDDHHAAGDDSQHPLSMSIIGTGDDEGTEVELDFTMDREMQSKFYHLMEDERSDVREEEEEETEDGSEDGKPTMTFAVRSASMSNPIPFRSIHGPGHPRAPSLASPSAATMTSIFSPPDEPTARWFYDEAGPGAGERAGPPSRIIPHHVEIPIGGTAASLSFGEKERDEAIRNIARENAAMKQPSSTPILIRHVLLRDFNICMRFFGGSDWSRDNINAPSLKHRDVPRDDASSSKPMLSVDARGGTGDRKEKLLDALVDNYVPSPAADLFGSEQGESSLFALSKTAPARTFMADRSTSSRSSGAIGTRKRSLKSGRKTEEMLELVVTRIQLRLDMFNDDEHQPLASNTVVALGDIEILDYISTSQIRKIICYWKSDISHPRESGSSMVHLHLMTVRPGPNLCEEHRLKVRILPLRVNLDQEVVNFLRQFIPTDDSATHRQSTVSTGEENESAPPMDGTELSVMNAPSPTRVRETDVSLGNWFFQNIDVRPCKIKIDYRPNRVDYQALRAGDYLEVINLFVLEGMELVLRRVRASGIDGWAALGEHVLMSWVNDISRHQIHKCVASVSMPPLRSFANIGSGAADLILLPMEHYGKDRRIVRGFKKGAKSFLKSVTIETLNTASKMAQGTQALLEHADDVVSSASSRRKQIKYRQPGSRIARNSKRMGGGGIRSAQDRGGIGSRQYLAQQPSNATEGLYQAYDSLSRELHVAAKTIVAVPLVEYKKTGSQGYVRSVIRAVPVAVLRPMIGATEAVSKALIGVRNAVDPELKEDVENKFKDFRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGL2</accession>
    <name>A0A8K1CGL2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005610</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043366">
        <property type="entry name" value="HECTD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46435">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46435:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="680"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="9">
        <location>
            <begin position="1640"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="9">
        <location>
            <begin position="1700"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="2062"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1169"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1674"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1731"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1679"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1740"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="2386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2438" mass="272719" checksum="5F9837DF3E26B590" modified="2022-08-03" version="1">MQRSTGRVVGVGGVVSAEEQGGRHSRSEEAASEREESPISATPKEDGDENVSNKNAWRFLDTKETYHFFNDEMVLSTNEMHHIEVEADAVTPSEKANAKVPKVVEPEDEWSEGDDDDGLYSKHDMPRIRKTSSQTLFEDVYPTFEDLYLPDLADMNPERRGRRRRRQKRQVNQALRAFCDDFHLGQTYLYQKRCEFLRVCHTRAADAERDRLHEARTIQEAEKTSAGCRDAETFVFQKADLILDASVPELFPRKWPHLPYRNPQEWEDNLPGILEFTRRVTELPEGSLLYEPVDIERFIVDACTFLEKAGVDTRCEESQAIESSMSETALAAICALLGVAVRLQSFSLLMLVADMLQFNANLSIHTNVPLLIGTIPAIARSIRDRLIALVDPNVRSAVSCRVNKCVSDLSAIITDSSVPVAHRLAAIADFVTLSDLCTSSKSLVDGFRGIADMLLEPTNALMFARNHSHTELIWMAFRSVFGRILESVDSSKEVRKYALSIVSDLYDRHIDATSKSISVDEAHVISRLALTVMASAHVFDTDLSVAEDWARRMFRLLRVDGLPAVVHVAAIRFLRRLFTLNDALWTKATKSSVDTTRVLLERIGRLLSNAGYTESRDESGDMDCCTLIFEDARVHAKVAEAIESVGEPDIEYLKIEIEERDVGTTPANLDRSEEESSMVHRNVRCDGCNQSPLRGFRFKCSICPNFDLCSKCYLNHDHNAEHQFVRMADSGGTGELLLPRSKGGGIIPAASVVGSKHWKGTVLSAYLTSYGLPSILDNQTVSRHGNAPLMLFQLAKECATGFKVDELEVKRGILRSMQELFFKSQHLSVATRPISRAIFSRDDSNVYRPDGKTLSDSTDFLFNMYAYSSRSELPQHSGRNKLLEYWEKNVIPAIESYVAGSFKSYEMDYFFAQLREPLREGNSAAAMKIAFTLCDGHVPSGCHYPDPDTDWTALQIDDIEVGERYLVCNQKTDASDWPRKMLWTIGHCGVARVVNPSGMVLLQLWNPETSRLEEWWYLVDHLKSSCEVQSVSQSSVDAFENAGERLLKVSKDLIGAFARVCVFECLKLDPDLFLFGDGRQPKMKKHFNIVELLRMVAKAELGREERAILGENVGKGDLQPNRELKRYELVKCLQAVFAKIFDRSFPLLEGKPEEHMFAAKAAKIQNSSKVSATSTARGGSVRHAHETANPKAEALRHRYKLMETLLNEQGRSFDASAAFLQQNALMVSSESPPKPLVMVHVPEASCLVLSFAVHPVLMDLPAGSSLEFFRDERCTDRIFGFFGEKRGLNYLPSIVVPGDRCYVKISQGAYARYKFRVDPLTPDFGLALWIAEELYQRLLVVPFSVFELESIMTSLLSGIAEYVVGTSLPPSVKAVVFQLISKLINFAISRSLFNAIPVAKLSALSHELSIAYENEKTTQKGLFSLYTHQVTELLSLVEEVCRLKGAFTPVFTGAWWGDFVRMASFTRVFVAKKEILGTDAFKRIYCGRAPVQEVRAAATLLKERDVYCERLIFVQKLPRTDQIECIRAALSRFIRRIALEECGEADDQSVFSAVSVTRLGILAQVLHLPVDESGHTQGYAIVDLGREDIVNNVILRLQKQKFEFVGAATEEDTQLTEQLRSLQDGVDAIGRSSETPVSTEDNMWPCGVCTLENTMKDIECAACGSPIPPEYADLASHHTPATSDTSANDNSASGEEDATECDGWSCESCTLVNLWEDFECAACGSERNPDLEPPAAAHTDGGDHQQEDTSTKTDGGLQHQISAVRVVDLFRIAEKGRVAQVESFLATKILRFGSTTNDHQYSEEFAALLEHDALRGELVGAHQGNSEQSSAKIGAAASADKLGSLVSANQTLHASLLADSCTLFELYRCLRRVGYDLDFQLSHYPCVDEALNTQVKWTHQMDMQLIALSRTLSASIGVLSLAELSLSHLSSASAADYPLLSMLETRDLRLRFQMLKAFNIMLLDALPLVNLHQSSDPNSLRMRLMAIRQLIFPAVKIRFFAQTQDNANLACSNMADQGNKRPMVTLDRRRIVARRSPTAPLLLQNPETSLFGSTMQQLSKVQPSLLRAKRPTGASDPFVSFIVIFAGEHVVGEGGPYRQLFNDIATELLSPGNPLFVPTQNNVMKIGEYRERYLPRPSSTSKELIRMYEFVGLLMGCCLRTGVRLNIRLAPIVWKMLVKQSLAVLDLEHVDWSLCESLKYLEATAFDASTGDDDILYESFTTTLSDGSCVELKPRGADIAVTKLNCKEYVRLVKTARLQECKPQVDAMLRGIGKIVPVELLQLCTWSELQQWVCGSLDIDIELLKRHTRYSSGMTPDKFPHLEMFWKVLASFSEENKRKFINFAWGQDTLPADDAEFDRTHTRLLVKMPTGNNQNQDVMLPKADTCFFNIELPAYSSEAIMREKILLAITLCTSMDGDDQAGRLEIYYAGDEYDDHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHD6</accession>
    <name>A0A8K1CHD6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5148094at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1444"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1538"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1617"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1737"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="831"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="719"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2755" mass="298840" checksum="B116E2D6927F5F80" modified="2022-08-03" version="1">MEDSSAQSAQNDVLKHWLETAILHPTQSISIHSLQNDVVDKLKSGELPLKRAINQTLVAATRSQYRATETHLRVFVQEATQHVDDFAKVFANVLSTRAKAFAQSFGSARLIVLRLSCAVVATTLAASEGTPVWLAEVIKAQSVLLESTLNDSERAQALAQKALLRAIQAHSETLLPVYTAAITESASADTQQYALWLVLSQLTLDVETKEKLWKAYAFWAFDAKARTFVTLKKNDRRFQGLTIEQFDAILKPVIAKVLKKSPDSALEAVKELVRAVPLDLGKYLTELFNTVILAKLKSTKEDVRDFTIGLTKELLEGFQSVEHFSTLVAQISAMLDGKHGLLAQFYMREAAFAVLSDAADAIVSLGRNNDVKNLALSVIPSLVKAVDKEAHDQTRHLGLLALGKWLALAEELPKDALTKIQAGLKNKSEAVVAGYLRALAVFALQSKSGVAALEPLAAELTRIALESNKKPTIAHLDGVLAVGVAGALALSSTSLDQKFAQDGVSALALDANAFVLSSVKNLQLSLAQAGDNGRVEGRTKPEATALVVLTQALSWVLSSKQEDASATYQLLVELLTSSVLPARRAAEAALRSVYASSLDHVDGLLVAFQTKLATVAETLEKEQAQFLARKPSTIADDGSSASTTIVPPAGVLRRALRVIVSERLREEDAADVRHNVFARVMVLAHHPFVIEGRTPSTFGSEWQQLKLRFLPEEAKEVEEKDTEEEEAEEETADDRIDHLIEADETVKESLKALLADATDGLLYSARRLERLAAQRTLATLLNFAGNGEGESLALHDVVEDALMHRIDEEHIDAISEEDVGVFETPFDEIYVPRKGGEGSATTPAGKKRGGGRRGNEDEQWEQQVREELEKKKAKQAAAANAQKKYTPQEKALLAQQQERRLQLKETITIVARVLETVEMLTTVRPDEIHPALPRLLKSLRALFQTKLFADEAAFALRALAKAISPELLREHASDVASSLGVVLRLPLLESDKAKTEKLADVEELLTRTLASLMEVVFGFQFDTEDDFDGTAPFNRIAPPTFHLVLPVLRAILRFDPALRHWALPLLATHVRMIPEEEEEEVGDVAAQRLLRKDMLELVLGLLSQAAAGDIRPITNDDLAPAHLLTELCLGPLLSATEWAPLLGDRGLLAEAKEVRTACLKALVAVTESEDDEVTTDLGVASNPLLTSRLFVACFDAVESNRTLAKGIWESTGAELPKLFAGPLLVLLNHRHANVRESASLALADGMKQFPETITPLLNNLQSQFQSHVPKAMESIDEFGNPTLRRPGQPEPLEEPETYLPRCGVALCLEKAASSGVAFTKEHVSVVLSFVLDHGLVDPNAAVRAQMRKTGIQLVDAFGGKGNTSSLLQLFEQALEHKPSAKSKDAAEIERYDHQREGIVVCLGALAKHMDKTDPKVASIVDSLIDALNIPSESVQRSVATCLAPLIPAVKERSPQLLTDLLTRATSAETFGERIGAAFGVSAVVKGLGISALKQQDLIPRIEELMKNGGANGRQGAMLVFECLSERLGLLFEPYIIVILPIMLKCFADASPQVREAASQTSKKIMANLSAHGVKLVLPSLLRSMEDGAWRTKQAGIQLLGSMAYCAPRQLGSCLPQLVPKITDALTDSHPKVRESSKNALRDIGSVVRNPEIASISSSLLNALEDPNKYTTEALQQLQSTEFQHSIDAPSLALVMPIITRGLKDRAGDAKKKSALIVGSMCSMINDAKDLAPYMEMVLPSLKGQLMDPIPEVRAVAAKAMGKLVKGLGESHFSDILTWLLEAIKGDYGSVERSGAAQGLCEVLVALGKDRVESTLFNEIFPLSRHPKFSVREGVLWIIAFLPPALGKGFAVFLTDALPIIVSGLSDEADSVRDVAMHAGHVVVNAHALSHTRDILPSLEAGLFDDSWRIRQSSVTLLGDLMYRISGTRAVGLSEVSGGDVDEDDDAAGSAAGDKAIIKTLGMERRNAILSSLYMIRSDTSAVVRQSALQVWKSVVANTPKTLRQILPTLMSVIVSALSGNNVEKQTMAGRTLGEIVRKLGENVLPEVVPILRDGLAKENPAGMRQGACIGLSEVIECCNKKQLEDFVSTLVDAILDGLCDELPLVRGSAAQAFDVLQRNVGYRAIDETVPALLQRIKSSHVEAQERALNGLQEMLRVKSREVLPYLTPRLLTTPVSPAAVKAISRVAQATGPVVHYQIEKIFGCFVPQYVEFLTVNPSFAEEIKLALRDVVLAVEDAGTHWLAIEVCKYCEKETVAERALAFFLIAEFCANTTTHYSDQAPVLLRQIVTHLNDSDEDVVKAASDALKGMNATIRPEEFVKHVDFIRQTINSLVSEARHRRGGVGANSVFLLPGLCIPKGLEPFLPGYQFALMNGTPEQRQSAAAGLGELVQLSSAAALRPYLIKLTGPLIRIAGDRFPGHVKAAILETLEIILEKGGVALKPFLPQLQTTFVKALNDTASEVRRRGTSALGKLVALSPRIDPLVAELTEKLSTTSGGIREANLDALASIIQTVGDKVSSAVRTSLEDALVVLLEDSEDVLRENASKCIAYSVITDSEQGETHALTYGLANAKDVSSLSWTRKHSAAVFWDAVLIKNPWWIGGCADAVANVLASLGLDDHVTVRAAAFKAIAQLVKHGLGAVDHFVPILTQGIQHPNKDVSKSAVKIAKRLAKRDPESMRAHVATLVPPTFQLIKSNNIAVKMSAERSLLYLLEVQTRPETLAAYVRTDAANGKIIGEYARRVLAKLKADSGDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHE0</accession>
    <name>A0A8K1CHE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002368</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHE0"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="385"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="160"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="512"/>
            <end position="513"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="686" mass="76421" checksum="2976BA49EC34B6B3" modified="2022-08-03" version="1">MVECCGVAPSRNVFARLPSYNPFVGTFHHAPSAGNRGAVYFSGDIVGMSELEERKKYRHHPLTGTFHSLPGYYDPLHRLGQIRHDEEHLSHCDTDSVRSYVAVDLADHEVYDPASIIGPPKSLSRMYSDSDTFSGNAGVAGRPRRFSDSDKEAIFAIPEAPHVMSNNQSPAGSPHAKDAASPEADSPTQKVRAKTLPPDQLEVIVGHVPLERRSSVTKRRKSSSGSTQSTESDLSTSPEDFMQRFERVELVRSVSSTELNDGFISTGKGIFRKVGLRHSFHDRERSNSKPVSPSRASFHWTNEDSEDDYAEEYTQAAPRVPLNPFVARRLTDGDEIRIMAVHRHNVPRERNPEVINAGSDTDDESSSVPKPYFIHERAVTEQYELNGADQLGDGSYAVVKPAIRRANGKEVAIKQIHKRYLTTEASKSAVEREIEIHLRLKHRHIVRLHEVYETDDFLYLVMSKAKKGNLKALMQRKRRLPEALAAKLAQQIVRAVFFLHDTGVLHCDLKPENILLTDARSTNQESNDSNSPKGRRGSLPSSLDPHADVKVGDLQVELCDFGLSVKVPDVRFYKLTGDVHKVPFTGVTGTPGYIAPELLQQQPYGKPVDMWSVGIVIYEMLTGYQPFYPPHACIDEKADFNDRVWSSVSAQAKDLVQGLLESDPTKRLTAADALSHGWFDAATFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHT0</accession>
    <name>A0A8K1CHT0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_002169</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHT0"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000150">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="18">
        <location>
            <begin position="175"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="486"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW63228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="514" mass="58623" checksum="8D5B622B13965128" modified="2022-08-03" version="1">MRPPREVTEAIAAYVPAHGSRLRPPLGSEKSFIYEWGVRVEFEEDNKTHVAWLCLADAECRRTKQNLYVMSHNRTSRAVKHLRLAHNIVSDKTSAEWGHKRKREDESEPAQLDAQPSERAYQPLPKKPLVDLPQRPTMAAEALTAWNGENEEQRSEVVEAIPRPITPTQEMRRILVAGGAGFIGLHLCKRLLEMGHEVLCLDNLFTSQRVNVLPLIQQYPNFEFIRHDVTEPYSCEVDHIYNLACPASPVHYQYNPIKTTKVSFLGAFNLLGLAKRVKGRIFQASTSEVYGDPEVTPQREDYWGHVNCTGVRACYDEGKRVAETLFFEYHRTHDVDIRVGRIFNTYGPGMHPYDGRVVSNFIMQALRNEDITIYGSGEQTRSFCYIDDLVDGIIRFMDCTTCIGPMNLGNPHEMTVFQLATMIIRLTGSQSKLVLCDLPNNDPRRRKPDISLAQEHLNWTPSVKIEEGLRRTIEYFSTLDLSKYKRPTNHTAHRSSQRLNSQQNGSSKPATTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHW5</accession>
    <name>A0A8K1CHW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LsmAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHW5"/>
    <dbReference type="OrthoDB" id="2275718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025852">
        <property type="entry name" value="SM_dom_ATX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14438">
        <property type="entry name" value="SM-ATX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="234"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="646" mass="68608" checksum="7CEB0655B37E6334" modified="2022-08-03" version="1">MQGSKTAAAPGSKAANQPRNATPNAANNTSKKANKKKQGDKPKTNGKEESDVKSASAPPPGFAPAPVSTPTTGFSEHQQRLLRHRALFAFRFLVGKAVEVQLVDSSRYIGILDCIDPDDFSVVLKNTQRKSESSEPFDSGSTVIFKRRQLAHMSADGVVNYTEGAVGATATATAGFRTDTEISGRSHEHLYGRELEMASSWLDPQLDTGELEDTRRRSSAKNAWNQFEANEKLFGVVSTFDENLYTTKLDKTKISNEQSRQAELLAREIERETTGNFHLQEERGQKVQREDLDEEALYSSVDRKQKTPSPTAVSRGPNAYVPPALRNAQQKQTGAGPAQTKPASPSAKTPATPAAAPPAGAASRKPLSFSEAVTGRTASAPAKEEPKPVSPKKAAPPAKNGQAKTSSPAPKENKASSKAPASQNDKKASKPATGEKPAKTEGSSTAAAAAKPLTAPAKKGLNPNAKEFKLSASAAEFTPKFMAPAATATSSPYQHGAQYPPHIHPAPHPGMGYAPAPEEWVYDPNFMLDDSEYAAAAYMGYGMPMVPNPAMMQQPVYPPMMHQQPVMRGQRGHGDYGGYAQQGMYNPRGYYGQGAPGYPAGAAGAPQPPLPREPTPTDGTAPPEDASAENAGATPPASKSDAKPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI03</accession>
    <name>A0A8K1CI03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI03"/>
    <dbReference type="OrthoDB" id="66563at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051599">
        <property type="entry name" value="Cell_Envelope_Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336:SF20">
        <property type="entry name" value="DUF218 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336">
        <property type="entry name" value="INNER MEMBRANE PROTEIN, PROBABLE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="121"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="35780" checksum="CE2C4DD30D63D44D" modified="2022-08-03" version="1">MSTASGSTTASSTSSRPKMVGTLLPQDSLRGLRDHRSKALAAMVPAPLILLPRSSSSSSSTTPPNPKLLAAAGLDLFRKGLAFDGLQPTHQEARHPAVKPNLLSIPEDDAMQTDPGTDCQLIVVIGGPLNSRGEPGIWVSNRIAMTIQLYWQITLSFDEDSAAPSTTCYVVPTASESSDEGIGETEAIRNALVGTGISPHHIIMDCTSTNVIDNAVQLVPILLQRHIKTIHIVTSEFHVPRVRLCYDTVLAAISDLSSLDIVYHSAPDGLTATARAERAATEQALMDKAQAELERTVQRLATDQHYTAARRSFVMREAHKQKQRPSTYNSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI56</accession>
    <name>A0A8K1CI56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI56"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="53306" checksum="625B928F547B5FA0" modified="2022-08-03" version="1">MCLPDIDPKVSSLQLTVEERQAVLEDDRVAAIDIIKDELQRIFVMAAPLLVAHELELVPDAMLMVMMSNSNPEHSTEVIAAMGLSDLLAMFVFESILGGVDSALGTLSAQAFGGKRFRELWLTLQAGAIIFAASLPVLFGIFFNGGAILRFMGQDPKLTETASTIFILTAMSFPLLMIQALQRTALQAMNITTPLAISAVVPYFVSLPAAYALGHYTPWGPSGMYASNVINNFVRMLILVPVVMRNPVYRESWPGWKPHEAMQLVTKLMRLGFSGMLMVTFQTFSFTVVSFMAGYLPNPAIALTSNSIFNQILGFAMSPIFVFCGLGAVRTGNALGAGQTRRAALASQAIVGLCVTVGLIWFVVVTTGAESFTRTFTSDSVAVSETTKLLLHAGIITPVMGAALGVQAIFSACGEQWFGAKLNFVSVLIIAAPLSWLFASEFNGGITGLWLGAGVGFLGVAGSTGVWLRHMSWDKMALNARTNTHLSVDEAHSAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI73</accession>
    <name>A0A8K1CI73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4">3.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endo-1,5-alpha-L-arabinanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002177</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI73"/>
    <dbReference type="OrthoDB" id="153639at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18831">
        <property type="entry name" value="GH43_AnAbnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422733" description="arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="9">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="34535" checksum="6179092FF901F94C" modified="2022-08-03" version="1">MKLLSIAATLLGLSASVEAYANPRACSGVCGNAHDPAIMRRADGTYFRFSTNGKVAVHTAPSINGPWTYKGAAIPAGSIINMPGRDGLWAPDVQKVGDTYYLYYSVSTFGSQTSALGVASSKTMDVGTWTDHGSIGVKSDSSKPYNAIDANLLVDGNNHYMTFGSFWKDIYQVKMAGPKKITGSAVQVTYDPKFDSIEGAYVFKHGSYYYLFYSQGQCCALDTKRPAAGKEYKIKVCRSAKPTGGFVDKNGVSCTNGGGTIVLESHDYVYAPGGQGVYQDPIEGPIIYYHYVDTRRGYADGDKLFGWNKLSFSSGWPVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIC0</accession>
    <name>A0A8K1CIC0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIC0"/>
    <dbReference type="OrthoDB" id="158896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="83" mass="9290" checksum="627671C005CA995B" modified="2022-08-03" version="1">MNSVVDETHTRSECLNQYRELKNKDELSAQCKEVMEALMATQSRIAENNPISIRGGNRTRNGVSHAALQRRFTGKMSGVHLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIY1</accession>
    <name>A0A8K1CIY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_005645</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIY1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000527">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000537">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000913">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053858">
        <property type="entry name" value="Arb2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22749">
        <property type="entry name" value="Arb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="14">
        <location>
            <begin position="421"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="537"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="801"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="389"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="475"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="512"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW63027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="98232" checksum="6CBE49DDD602B8BD" modified="2022-08-03" version="1">MAFRFPRWGRSKSKENNANVGNKYPPQTSNGRLQGGQYPPHQPQYAPPPQQQQQYQQQQQYQQHPRAPPASMGGGLPPSRPASGSVSRGAQLPFSHPLYAMDNDGMIHLKATGKGLDDTDIAVHQDEIINSVVRYVHDSMRRELGFREMHIPSSDAPVKANIFVSSNYETASKLLVFVAVSRGLFPGLWSRGLVLHAGVKSGSMLEYFRKAIDEGYGIIVANPNKNVIVLRDGKQRLQIPGSASPEEHMDSLWDRYIAPSQAKRVYFLGYSYGGVLIKYLLHSRGDQLMRRNGAIALIESSHRIEDGDSQSVKSILAHRTMYWESNDLAFQTRLDGDAPHRTGCTCLSAGKPPRAHSNHYYVTAYCINKIQDALFRFLEIRDANKYVEGERPVPDPPQSAPAAVGTLQRQGSRRDTKFNNQGSEKHCNLCLFHFTLFDRRHHCRMCHRAVCNACSRDRLFLPGASTAQRVCSECATEGARPPPQSNSRVHRATSDAYDPPKQSEERQRSDTDMSNGRSASTVQQNERPASKLSVDDFDLLKVIGKGAFGKVMLVRKKVPDGHNNPNAIYAMKVLKKASVFAKNQVEHTKSERRILRDIDHPFVVRLRYAFQSEDKLYLVMDYYNGGSLFFHLRKSRKFSEKRAKFYAAQLLLSMAHLHELNIAYRDLKLENILMDDKGFIALTDFGLSKENVDMPDGAKTFCGTAEYIAPELLKGLPYGKGVDWWGFGTLLYEMMTGQTPFFDRNRKRMFHNILHRDVVFTSAFSEEAKDLLTALLRRDPAKRLGSGPSGAQEIMDHPFFASIDWDKLMLKELEPPFKPVVTSEADVSNVANIFTREIARDSPVTQQLGETHRAQAHFEGFTYMPGSELTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJZ0</accession>
    <name>A0A8K1CJZ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_014172</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000904">
        <property type="entry name" value="ABC transporter A family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000298">
        <property type="entry name" value="ATP-binding cassette sub-family A member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="519"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="652"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1118"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1328"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1389"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1420"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1457"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1488"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1533"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="744"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1596"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1065"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1999" mass="220729" checksum="41780F833EA7CC0C" modified="2022-08-03" version="1">MLRPPIDPKAQSAFCLVELMSASNDSREVPSSSRATSVTHIRTLLWKNWLLKRRHFIATFLEVAIPCVFVLVLGILKKETDDVSVPAGWSDDNATAVDDTIGTAYNLFDPIGAFNRWVPTLLPRFYMHEGSMTGLLLSLGAQSIADGYRLGELPETDRTKCTQFVSVNGYISTNLSSPYQVPTACGGRVAPYKIGIVPDTDFTRQYFLKTMDQWYPRIKFGNLTGGVEIPSFRDSVEFFKSEEDLEDYVKGKEYGEDATHPRIYGAIVFDKYPADSDIGKFESIEYTIRMNSTLGRGQVIGVIPPTNGDPPAFSPFQKSIKVDYYSRYAVTGFMTLQTLVTRFVTCMPKWDGSKKTTDGKCQHAQATAIASDELDDRLLTSLNEDARIKLALSAFSSGSSAGWSLNNASSLTNSLLASLNGSVLKFTDALALADPTVKEALLKPLRQAPQPYLGGAVAPFPIDAYVSSPFYDQIKDLFALVFILAYLYCLSRVLVVFIQEKESRIREYLKILGVKEKNIVVSWYITYTAILFVGSIIQALAGLAGLFENSSVVVIFFFFFLFGLSVLSFGFLVSTLFSKSRAGAFVGIIVFFLIYFVSTIFKPQTSETTKSIGCLLSPVALSLGVRVVANLEATGSGITFSNISVPSENFRFGTSLIFFVIDSILYTALGLYFEKVIPKDYGTTLKWYFPVSPSYWRGRRYNRLPQKDELSSAESLDNVIVDVNPAFEPVNAELREQERNGDVLSVQRLRKVFPVPGGEKVAVKGLNLVMYKDQITCLLGHNGAGKTTLISMLTGMIAPTSGDATFRGLKLTEDMDEIRESLGICFQHDVLFADLTVEEHLIMFGRIKGYAGDELQQVVTRQITEVGLTEKRGVKSSELSGGMKRKLSVAVSLLGDSSLVFLDEPTSGMDPYSRRSTWEILLNNRNDRVMVLTTHFMDEADILGDRIAIMSEGELRCCGSSLFLKNRYGAGYNLTLVKDDQACNDSEVINFITSYVPSAQVLSNVGSEIAFQLPLDSSSEFAGMFAELDANLSQLALLSYGVSVTTLEEVFIKVAEAGDEDNQHTLTKDARVVDPVPVPSPTNSSTSSSYTVTNRLFSAHLHALLLKRFRVAKRDRKMLVFSTILPVLLLLAGLLLLKASGLTSNDPKLALTTDVYMAKGQSPTPFFCQADEDKWCSTTMNAFTGASPVQLSSDVVKEYDSDSPTVLGIKYTDPKINTSDATGYGLRLGEVLYERAYGKDRANAASQYNAYGAYLVHGESERNILGYNLFTNTTSTHGAPTFKALMDQAIYRFFASNTSSGASTSVDLKVNNHPLPLSASSKALYTSFLSFSSCLFIVIAFTYFPASIVVFLVKERESSHNAKHQQLVSGVSLPAFWLSNYLWDMAIYMVPLVAAIILIQAFNIASLTGNDCVSCTSATFPSVILLFLLFGLAICPFTYCMSYIFVDHTYAQTYTILINYMIGVVLMVVSFILDIIDSTKELNKILVFFWRLSPLFNLGNGLLGVSINEIESVLYNNKEKTSPFSGKQLGYEALYLFLSAIIYSALAVGIDYALTFPRVKNLTENGRSVEEEQYEEDEDVIKEAHRVQSGPVDDVVVLKNLRKVYKGGKVAVRNLTFGLKKGECFGFLGINGAGKTTTMKMLTGDVIPSSGTATLSGFDILTQQIEVRRQIGYCPQFDALFELLTVREHLELFARIKGVSRAALDDVVSEKIQQLNLASFENKLAGSLSGGNKRKLSVAIAMIGNPQIIFLDEPSTGMDPVSRRFMWDVIAGISTRGKSSTIVLTTHSMEESEALCSRVSIMVGGRLRCLGSVQHLKSRFGDGLVFDVKMTAPSHEELQEVVDRVMFDANAFVSSDEIADKCRIFGNAELASRVSADHPTGYSLAAALERDGFIRGPAFCSWCVEETRFDALHRFLGESFGDDNILVMERQNDFCRFKLRGSNAQLRLSTVFDRVERVKSKMHIREYSVSQTTLEQIFNQFASQQSEEQGVARGMMTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKU6</accession>
    <name>A0A8K1CKU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014224</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKU6"/>
    <dbReference type="OrthoDB" id="15808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000002">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="39561" checksum="D5769AC68398913B" modified="2022-08-03" version="1">MTRRLLRSVSPHGARALSAAVTPRVLSGIQPTGVPHLGNYCGAISKWVALQDNQTAETRGQRLYTVVDQHAITVPFDNKKMPRQVRSTAATLLAAGLDPKRNILFKQSDVAYHTELAWYLSCITPIGWLNRMTQYKQKEQQQKMESGLGLLAYPVLMSADILIYKATHVPVGEDQQQHLELARDIAATFNDRFGHDVFPKPMPVENDKQASLYRIMSLRHPTSKMSKSDPSANGRIDLTDSADQIRKKIMSATTDSIEGISYDKTERPGVSNLLSILSAVTDATMDELVQEHATRRTGEFKKIVADAVIAKICPIGERIQQLENEPAYLESVLAEGAEQASALAAKTMQEAKKAMGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKY8</accession>
    <name>A0A8K1CKY8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008183</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKY8"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="689"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="809"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW65541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="875" mass="98708" checksum="B0ABC51923E3D155" modified="2022-08-03" version="1">MKWLRSEAMEYISLIVNEDAAHDCVQKLGDLGVMEFTDLNPELTPFQRRYVSYVKRCDEMERKLRYFEGELSKFSITPKSAGTIDQFLAGSADIRYGSQDTAVRALDTLERILEDKEQELLQLNSMHEKLTREYNERKELQEIISRAGEFFEIDIPDVQRGSSFRTSSRSTPGSGYGFNVGSPSAQALVGGAEGESSLRFRNITGVVPADERLKFERMIFRTTRGNCFSRFSPIQDPLTDPSSGAPVEKHAFVIFFQSTFIENKLRKICDAFHARLYTLPSTDDRAAIASLIQSNNTELNQASHILRRNRESCVLLCRDLAENLESWKWSVLQEKATYHTLNMFRADVSGMLRAEGWVIKSALDSVRREVTRAHNADDKSMPSLVDKVPKPWPVPPTYFETNKYTEAFQAFVETYGCPRYQEINPSVFTTVTFPFLFGVMYGDIGHGFCVLLFGLYLILTEKRLEKGNMGEMLTSIYGGRYMLTAMGAFAIYAGLVYNDFFSLALNLFGSKFAYPDCLEDTHSEAKCEAMFNINGKMSPVNATDVSSGANVYGFGLDPIWKTSENELLFFNSFKMKLSVILGIIQMIFGIFLKGLNSLYFGDYSGFLFEFIPQLVFAGGLFFYMVILIVMKWSIDWTERMKHEVCPFDFEGPRTGCRPPALVNTLINIALDPGRVVDPMYDGQLKTQQTLLMLAGLAVPAMLCLKPFYLKLTHTSAPAVRHHVDEEEEGRGGHAHSSGGHGGGHGHDGEEFEFGEVFIHQGIETIEFVLGMISNTASYLRLWALSLAHSELSTVFWEKAMISAINSDSFIAIFIGFAVFAAVTFGVILTMDVLECFLHALRLHWVEFQGKFYKADGHRFHPFSFKQVIKESKAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLA1</accession>
    <name>A0A8K1CLA1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008199</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLA1"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="53"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="59"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="29430" checksum="A1EAEBFD600D56DB" modified="2022-08-03" version="1">MSDKEHKAARFAATDDQETPKLDSKEVLIVKDGKIQLAHPQKEPEPQFDANGERIKASGTWSESEHERFLKAIAEYPKGPWKAIAAMVGSRTVRQTQTHAQKYREKMARRIRGLRNRDGSLQTPPLRVITPSRRVYGHVFVPIAVYDLPANGFGPGMSYVPMMTTTSPTSPSQVMISATPGPDPTLYYSTTPAYSHPGYISTHPSTLSMPPSQAPKQAECTIVPLDPRPDAWNQISLTTQPTGPPTDLLEATDLLLTYGASGTSHIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC8</accession>
    <name>A0A8K1CLC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC8"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="4">
        <location>
            <begin position="28"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="331"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="394" mass="43879" checksum="B288F8E2171A53EE" modified="2022-08-03" version="1">MGLADAPREKNSRIECYDAANDRRKLGVAVELEEDKWPNGIVWYRISSDFDDNQRRILHQAISMYEATDVNVTFKECEPPTLCNNKYVDMKKEEDACYSYVGYVDDGEPQIFNLGDSCFDGVGTAVHEVGHALGLYHEHTHPQREVIVLTDMDLPVSSSNYAKETDALLKPYDKASIMHYGRTAALCLPKDEYALVSFCDVEITTNCTMPLQKHCNDMRDHEIGQRDRLSEGDIASLKALYGVKHTNPVTLTPLPTTSPTQAPPTDSPSTQPPSPTQSPTSTPVTPTPPSYLPSPAPSDGRPSSVKPKPSGNLSPWLRPWEKITKDLKRFGDLPWEKGTGRWWERPNKTPSASKNDAHEETGVVPGLGWIQEEIIKVLKPFLSGSTRSKQLRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLK8</accession>
    <name>A0A8K1CLK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_009360</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Mg(2+)(in) = Mg(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29827"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="165352at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12822">
        <property type="entry name" value="TmCorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000021">
        <property type="entry name" value="Magnesium and cobalt transporter CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000004">
        <property type="entry name" value="Magnesium transport protein CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418908" description="Calmodulin" evidence="17">
        <location>
            <begin position="36"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1622"/>
            <end position="1645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1657"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="726"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="1258"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="620"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1007"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1125"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1134"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW65193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1684" mass="186496" checksum="85A99098C111AE45" modified="2022-08-03" version="1">MLISMSASSGGVRRRRLLVQSLGLGLILFWTHGQATETGPGTVSAPGTWDQAIPEHTLTTSCGAACADATGASVCLGLADTKKNCQGANKMAGVTCASSSDSSASSVLCMSPDKSQWRFQLTKDPELLAIGRQGVVLTEDLGVAMTLDAGSAQTVGDFKLAPETNQLYLSAANPAEQLTVTVSTATIAQWSNLEVLSLRNLDLSTVSGLPTFPKLLTLDVSGARLAQWPILESAPALASLDLSFNGLTTIPAGSIPAPLTTLNASSNSLTQLPDDLASLSALRKLSLSHNDMSQVAEFPELPALKSLYLSSTNLGVLPSGIETLPQLDTLDVSDNALGDLPEDVLPPTLTTLIARNTGLTKLPAIFDVDKTWERIDLSRNALNDEVLAPAQFRAVNLTLDDNDLTALPPNTKIWAIGTALSLSNNAFGTVDAKDLPASISDLRLASCSLSAVPSNLQSLPRLEYLELSSNPLGTVPAGTLPKTLTDLLLATCELSAVPEDVSALSATLKTLDLSTNKISDVSALRLKDFTSLRRLELQNNHLSSIPDDVFSIKQLSHLDLSGNPITNVTLSQVDFHFLATQVRYFAIDPAAFESATCANRWQLRGKYSVCVDGSGSYDPSMENREMADAPQRDPLASPTQASVSDEKDSKSSFAPLNIVVIAAIVMVFGVSLFVHSNRRKKQALGTATKNAGDDDYDALATMRRFAPVDMWEDAELLYWRVDAQDLELTMQVGTSASSVFWLGRYQTETVAVKRLSQKKPDRDTFRLFVDEIKAMSKLEHPRIVQFLGVTWTSGSDLSMMMEFMNHGDLQKYLQSTKGDVDAKHWTSRKFSIAMSIADALVYLHSLDPYVIHRDLKSSNVLLDENYNAKVAGFGSSRLRADNMSTSTRWIAPEVLSGSDKFSEASDVYSFGVILSEMDSHELPFSDITLSNGKPLADNAMKELLIAGALQPTLSKNCPKEIVDLIGDCMAMDPNRRPSALQALERIRRAVEATTAIARFTSSVVRVSRPRSDHSDASSNDLNKSYYIRDGRHGRRLGSRHFLSPSQRRRGAKQSAPLHTQELVSVVPHDVALEVTHADDLLLPETQDLHESVEPSDWASEEGARRDLTSAVRRATLIDLTRRESLLPRLAPEPQVSTESSTVSGGHRSPVHSPADAHVPTQKAYKQQGRKETLHGKDLRQFVSIGSIDQIPRHSNSVDWSETSADSDEPDHLSLMDPYYDLTKVKLTRLFSLFQPDASGMVGYEGFRRGLEAMGIVCADDDDFRAFINKVDEDQSGGISYEEFQQAVQEIKLAQLFNNDFLHEMSLDTLHIKRQPVILGSIEYSPDRIRTVYPIGNLEKFIYSRKPTWATVRWINVEGNDPLMIRRLSVRYRLHPLAVEDALEVDRERPKYEKYDEHSLLILQTVHPVDMSKLRQYQKMYRNSLYTRDEGPSQVELMDRKELEERLEGLKAGDLMTNPDQLSIYMLKDVLISVQERSGPLWNAVKTRLDTSYSKIRQHGTRFLVYSIVDVCVDDLTPIVHTLGAKLLMLERLLMLDPMRFELVRLQNSAKQLKGLKRLCKPLKEVIEQMSESNDFSGETLRYFRDVQDHLVIIEEDCEKHLDTCRSLVDAFHNLRAARQSDVSYVLTLVAAVFLPAQFLTGLYGMNFEVMPELKYEYGYYIWWAVVLSIAVATVSYFHFYKRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM89</accession>
    <name>A0A8K1CM89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM89"/>
    <dbReference type="OrthoDB" id="107786at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="578"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="626" mass="70408" checksum="D266EACC93A45DC7" modified="2022-08-03" version="1">MLQSASTFRPSSQLGPLRRPEPRNIVRFNTDTLPEEDTRLAPGDPMPFFHKRHIGLFISVICAGMLASLLKRGILPLMQSEFGLKPYQRESAEVILMMPWSFSFLFGFFSDALPFMGSRWRSYMIMGWYVTAIALLFMSYFHYYMQKKVAKGTHDPAKDVSMYMFMLFFACFGNITSIVIGESYAVVQEKRYPRARRGHFVANLLFIQYAAEGVGQIITDFAIVNITKDGVKPLLSFQVLLLILCFFSLVPILALASHFHPAYDIGKEGELDLDYESARSMETMTTLDELAYSSKQQLAVLMSPQQLDRIPFEEQVQAFTKHMRTHLLIVWHTLRKQSTWHVVVSLCLFVFFSEFTLKYPHLQLDRWYGVSFKTESTCKILAEVMCCFGIYIWKVACSNTDWRRLFALSFVCLMVIPQMAAYILAAFNVGRKVGIYTLVSSTRGFVRAILVILEIVMVIEIAPMCGEASAVGAIVSVNTIMRLVSTTFSNTIGYVFGSKVLLTLKAADFMTNSTDLEAAKDEESATNKVAKSQKQLVATALVLCYCIRLMALSGLLCAPKQKHTLQLLMKTGRESTRYAVMTLGMLLTAILISMIVNALVLKPSITCQQAMGGMGCKNVHPSMVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPJ4</accession>
    <name>A0A8K1CPJ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPJ4"/>
    <dbReference type="OrthoDB" id="158009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="593" mass="66639" checksum="F195C35DF972032D" modified="2022-08-03" version="1">MQQHVERSAPVQIRGSPRLHGFQWPSSTNAVHPVSMQDLNRHHHHGHVDYVPHRVRRDVNTPDGIVPNEWICSPLLDGFPSFHSSVIGSEGASTSLGLAASHDELNCSLPYLGTCWSHDHNNNARIEPIHTNNVTIEHPETPHSEEWEYLKRRSFSTDFPSPVQLETFAPLFFPMDPDTAMASSERTAESSHVQNFQHPPSSNQCESPMEDIPVSHQHTMPASTQGMWQEMHEAPSDLIAPHDAMMDASVFQGHSQESESSNPPLFTSPHGLPPTSTMLCPPPRHESMSSFASLPYHPAPRPTPQSPLFADVQLLTKLNHCYWKNGRKNLQCFPVCPEHNDFYSMKMNNRKHSSVGVCRGPVYCHAFLPASTTGTVKPEASGHHMKYEFGVGATGTGGSGHEVFVLGKFERVPQQNEMHSLEELLPPPLHFTSSADFEAFRYSCFQAVEMEERRVLLQHNNGVVTPSTTQGNLVRSTWFFLPDVWKVQPMLKKKRKATRSAPAQTFPFCFRIFIYTRDPVTPSNEPAYRCLASTSSSFFELYSTRTVDRVKRKYWTSSSTASDGVDTPLPPHTEPTKPSSMSMTMRATKRLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPY7</accession>
    <name>A0A8K1CPY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdopterin cofactor biosynthesis C (MoaC) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPY7"/>
    <dbReference type="OrthoDB" id="429626at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin cofactor biosynthesis C (MoaC)" evidence="3">
        <location>
            <begin position="42"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="199" mass="21474" checksum="ABB5EBCE1AE6E44C" modified="2022-08-03" version="1">MVRTAAWRCVQRASKPLPVCTIPRASFSSFTHMNAEGTSPKMVDVGAKQPTRRTATARSIIRLPPEVLRELKRVGNKQHTSSSDDALALTGPKGPIGTTAIIAGVLGAKQTSSLIPFCHPLPIEDVQIRISTPSDDRIAIECEVSVTHKTGVEMEALTGASVAALCVYDMCKALSHDIVIERTELVAKTGGKRDFKRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ10</accession>
    <name>A0A8K1CQ10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium uniporter protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_012245</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCU (TC 1.A.77) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ10"/>
    <dbReference type="OrthoDB" id="278338at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990246">
        <property type="term" value="C:uniplex complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015292">
        <property type="term" value="F:uniporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036444">
        <property type="term" value="P:calcium import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051560">
        <property type="term" value="P:mitochondrial calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006769">
        <property type="entry name" value="MCU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039055">
        <property type="entry name" value="MCU_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462:SF10">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04678">
        <property type="entry name" value="MCU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium uniporter protein C-terminal" evidence="16">
        <location>
            <begin position="200"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW67129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="49851" checksum="14A7B0DA43A5E975" modified="2022-08-03" version="1">MLQRLATTRLLVQGAQRASVQRPWALAAQQQLTRSFMQTAVLQYPRGLRALEMKYVDGSCTLSVPLPLDGFDEERVFSIPPETTVAEIVAQITAEDTTVQTVELRSKRGKSFKPQDTLQQILTDDFELVINERTLHVTAPVFTGNAYTSLLDDGELDVRSVTQKSAIIALRHNLEQMQKWKISYTDFVELCREQGIPKKQAPEVLKSFHQAGVVLYFGAADDEDLQHSIFLQPRNIIDSYLASLGLTPVTKQLFAQEREKLLRKIQSLEPEHIALRNLKKELHNAATRHANGIAYALSTSLVGGFGLYFWLSFIYFSWDIMEPVTYFTGFGVSIVGYSWWSITNQEYEYENIYDYFYQKKLRKLKKNAQFDESRLELVRKMIDDTSSRLHQVEQVLEKAPSVQANYLSLLDSRVDESTEFYPAPASTTHVAEKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQE9</accession>
    <name>A0A8K1CQE9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007583</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQE9"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="30948" checksum="8648C7ED5678BD99" modified="2022-08-03" version="1">MTSTSTNVWLITGCSSGFGRELALAARRHGDLVIATARKVEALDELKNLGCDVLALDVTASEDVIKQVVDEAHALYGRIDILVNNAGYTIFGAVEEASDKDVFEMFDTNVFGLLRVTRAVVPYMREKRSGTIANIGSGAGYVPFPTNGVYGATKFAVAGVSQALAQEVAHLGIEVAVIEPGMFRTNILSTGRTFQHSIADYEPIRKVFDHQMETGFSVPPCDPAKGAQAIVEALTKTGRCVGRLLPRRLPLGGDCLPLMDAELALREKEKNDWVDFVDPKAFAFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRL1</accession>
    <name>A0A8K1CRL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA ligase</fullName>
            <ecNumber evidence="14">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_005772</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRL1"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000002">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF4">
        <property type="entry name" value="DNA LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="17">
        <location>
            <begin position="633"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW68304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="915" mass="101799" checksum="BD206D59D1A20A44" modified="2022-08-03" version="1">MAGASRTKPQQTSITAFFGAGAKSPSPVAKRKAEDTPKKTQRKKKEEEEDAEEEPKKRKVATPVKKASVKAKRVVMADSEEDDVDMAEPQTEEAEEEQSPVTKGKPGRRRLRQRVVDDDEDEEDDELSFPPGKKKEEVVEIESEEEKEKEPAKTQKQEDKAVSIEKEEEEDDDGDEDYKEEEQEEEDDDAEEEDEEEEEEPPAKQKKAAPKKASAVASTGFFAVKPAKKEKAAAAATTDTSVTLDDDVESIPYTALASLFSKIEAVTARLVIQDLLTNFFREVMRKAPQDLLACIYLCVCTDLAPPFENLKIGIGDAILMKAIGEATGTAPKFIKEMYQKEGDLGKVAQNARSKQHTLSFASMKPAADARPKVLSVPDVYNQFVKIAKMTGNNSQQQKCSIIKNLLVKCEKDKKATSEKGEGAAEAAKYIIRGLQGKLRIGLAEKSILIGLTYAFMLEKDAKDKEKQEKALAQVKKAFAECPSYNALVKAFQDVQETVETRPFLKVSDFTKVAELCVLTPGTPVSPMLARPTKAYAMVFDRFQGQPFTCEYKYDGERAQIHILPNGEIAIFSRNFENSTERFPDVKLMIQKAAKKSQIKSCIVDAEVVAVDKATNKRLPFQVLSTRSRKNVKVEDIKVPVCIYAFDLLYLNGESMLQEQLTKRRSILKEMFEVEDGSFEFATSMDVDGVMPGVDDAEAMEVAVDKVRTFLEEAVKENCEGLMVKTLEKEATYEPANRSHKWLKLKKDYLDGIGDSTDLVPIGAFHGRGKRTGVYGAYLLACYDPDTEMFQAITKLGTGLSDEVLKEFSNQLKEKVVDRPPSDYAIADGIKPDVWFEPSCVWEILGADLSISPKYTAAMGLVAKDKGISLRFPRFIRIREDKNPAQATTSHQIADLYRAQGLATVGGDDDDDDMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRU5</accession>
    <name>A0A8K1CRU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011131</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="680"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1113"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1144"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1184"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1221"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1250"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1349"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="86"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="770"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1375" mass="153802" checksum="38F480A7C7CA92D5" modified="2022-08-03" version="1">MEKESLQHISPMTPAIEYDSGKALMQHGAEALHEHVSTRIEAAMGQAMPQMEVRFKNLSISADLMVSSEKKTHELPTIANEFKKTFRRFSAKKHKVTKHILHNMNGVFKPGSMTLILGQPGSGKSSLMKILAGRFPMSKNVKFDGEITYNGAGRDEMLKRLPQYVSYVTQRDNHFPTLSVKETLEFAHECCGGELSEREEQRFNQGTPEENKAALEATRALYKHYPDVIIQQLGLENCQDTVVGNAMLRGVSGGERKRVTTGEMAFGNKYVTLMDEISTGLDSAATYDIIKTQRSIAKKLRKTVVIALLQPAPEVFGLFDDVMILNKGHVMYHGPCDQVVGYFEELGFKCPPHRDVADYLMDLGTKQQHQYEVARADGSKHPRKAREYADIFVKSGIHDLMLTDLHGPHDPVLLKDKEEHFDQIPEFHQSFIASTRTLVRRQMKVTLRNVAFIRGRGFMVILMGLFYASTFWQVDPKNVQVMMGILFQGLLFLALGQAAQIPTVMAGREIFYKQRGANFYRTSSYVFACSVAQIPLAVLETLVFGTMIYWMCGLATSFVPYLLYELLLLLTILTFAACFFLLSALAPDMHIAKPLSMVAMFTFVLLAGFIVGQNQMPDYFIWLYWMNPVAWCLRALAINQYRRPEFDVCVYDGIEYCKMYGKEMGKYSLSLFDVQDEKEWVGWGYLFLIGSYIFFMWLAYIVLEYKRYESPEHVAMDREEDDANFELASVVSSTGSDYGLIETPRKKSTSEIAVEVNVVARERYFEPVTLAFKDLWYSVPNPTDPKGAPLDLLKGISGFATPGTITALMGSSGAGKTTLMDVIAGRKTGGSIKGQILLNGHPASDLAIRRATGYCEQMDIHSEASTIREALTFSAFLRQGSDVPDSQKFDSVEEVLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKVIMDGVRKVADTGRTVVCTIHQPSWEVFSVFDSLLLLKRGGQTVYFGELGAKAVELKNYFEAVPGVAPLTEGYNPATWMLEVIGAGVGNTANNDTDFVSVFEASEKKALLDANLARPGVCTPAPGVSALAFKSKRAASNWTQARFLVGRFMDLYWRTPSYNFTRYIVYIFVGLVLGLLQLNGNFETYQGINAGEGLVYVVALFTGVVSFNSVLPIASEERAAFYRERASQTYNALWYFVGSTVAELPYVFSATLLFMAIFYPMVGFTGVSRFFLFWFNLSIGVLMQTYLGQLLAFAMPSVEVAAIMGVLVNSIFFLFMGFNPPANAIPSGYKWLYHITAHKYVLAILSSIVFGDCPEEGDLSELACRPLQNLPPTVPANLTVKGYVEEVFVMKHSELWQNFGILLAFIVFFRLLALLSLRFINHQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSA4</accession>
    <name>A0A8K1CSA4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSA4"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="233" mass="25408" checksum="52987C8538EBB0F2" modified="2022-08-03" version="1">MQSLGGTVAIVTGANSGIGYEAALELTRKGAHVVLACRNEQRGQDAVKRIVKRFTDAFKKAHDRLNLLVDNAGIWGIPYTETEDGFEAMMKTNHLGPFTLTVQLFDLLKASAPSRIVNVSSLAHRTALSFDEDKIMITKDKYKPWLAYSNTKLANLYFTLELTRRFEANGITGVSAIACHPGFATTNLSFPAIEKQSLLYRAAYRVGTSIPVFQSAAMGALPTLYAATEVQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSP3</accession>
    <name>A0A8K1CSP3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001328</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSP3"/>
    <dbReference type="OrthoDB" id="5351233at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010387">
        <property type="term" value="P:COP9 signalosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033205">
        <property type="entry name" value="COP9_CSN8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339:SF0">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="39"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW69172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="236" mass="26474" checksum="EC3CC206D13F14E4" modified="2022-08-03" version="1">MEDLLEKLERERAQLLLAVLEVEDIDRMRTRKRIQSLKDVYEELELVAAAAAPVVHPSEGASNPNPAVLTADFYASYLVVLLLAKNLNDARFLWKRIALETKQESEPLRNVWEIGKALWERDFTAAYAAMSKTWPETLGPVIAVLRQSTRESTAELLSSAYSSISFNDAAHALGFDDEPSLLQYCQALGWSVSSADHMIHPKPLPQTTTRAAALEQLDTISQYVLHLEQNTLVKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSX4</accession>
    <name>A0A8K1CSX4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSX4"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF177">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487027" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="26"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="611" mass="69524" checksum="A0121BFA52023611" modified="2022-08-03" version="1">MMVTTERRAFVWALLLCSCVLQCVAGEGNEFGVRDEVLVVANTVRPYANPTETYQYYKLPYCKPKERQWDDHELGELLTGSRKVVTDYKIYFGVDQDYAQLCKLQVTPEIVKAFRDAVDEDYEISFFPSHFNCDLMIMFIGYLVQESVTKVNYFLYTHLHFDISYNKLEDGSNKHQIVGANVSVVPLEKDIDYRYTLSDANVYRNPELVFTYSVKWHFHPELTYESRNKMDEGETATSSDELELHWIAVINSFILVMMLVAFLSIVMIRILKRDFTRYMDVESGEESPIHDDSGWKLVHADVFRVPQYLSLFCAMNGAGAQLLVMLLTVLVSSLLGIVKPNKRGGIITAFIVIHALTSFVGGYRSARLYRQLGGQRWVWNILLSVLVIPGPLVAIFSFLNTVAIWNDSSAALPFGTIMVVVAIFMLVAFPLTVIGGIAGRNTTGDFDAPCRTNKVAREIPSVPVYRSPFILIFAAGCLPFSAVYIELHHIFAAIWGHSIYKLFGILLLSVIMLIFVTAFTTISLTYIQLSSEDHQWWWRSYVSGGVTGFFVMLYALWYYKNATVMTGFFQAAFFFGYTAMMAYCVFIMLGFVGFRSSLVFVRKIYSTIKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT23</accession>
    <name>A0A8K1CT23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT23"/>
    <dbReference type="OrthoDB" id="70673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="364" mass="40186" checksum="18EFA3CECF26E187" modified="2022-08-03" version="1">MMRAVLLAKASVTWTRLLYVLVVTFTFSLIFVARKMTEFPWLDMLHETSYAASARIVDNGWIPYVCAVVISVSVPVVVALRCSGVVSKLVIRLLSVVVMLVVSLFYVVMVFGVVGLVGSWRNYSFSSRLDATELVVAHEFNSLYCESQTEFFCDRAALSELLQVNFGQVVLANSSKKQSDEVVASCLAHYGLNVTQELPAWAKVCAYCVASEDTEHFKGFLNWISDECRPKNQTLSWCTGSQADADSARATIGSPYDVCRTPFLDYTHYWTRTLGGLIMGNVICLLGILASSLYPLIPRKPTQPVEVVPITEVPLTPTYEYVEVVKGSDISSLRSASITSAESDESDIQSGTSTLSSLSWYMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTC3</accession>
    <name>A0A8K1CTC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001376</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTC3"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037188">
        <property type="entry name" value="U6_snRNA_Lsm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="35"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14261" checksum="22D1F740647D2744" modified="2022-08-03" version="1">MNEELRHEQRRMTPQKKTTMATNGSSGGNAPARRDQILDLAKYIDQPVRVKFFGGREVHGFLKGYDQLVNLVLDDCVEYLRDPSDASRVTDETRKVGLVVCRGTSVTLISPVDGTEEIPNPFLPQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTY6</accession>
    <name>A0A8K1CTY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001706</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTY6"/>
    <dbReference type="OrthoDB" id="1718410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243:SF11">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER YGJI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="76208" checksum="273E409D31637825" modified="2022-08-03" version="1">MSDYHAVSTPMLPDLQLRRRAIQVNVPVETEPRGPIWTYPGLGSAKDLEVPHEELDQLREKVGKKTHQLGEWKATAICGNDILSSVLYSSGQVAVKAGKLAPIPMMLVSLVLYFFRFIYEEVVTAIPLNGGSYNVLLNTTSKRVAAFGAALGILSYLATAVVSSTSAVHYLSIEADLPLVGSTVGLLFVFAVLNLFGIGESAVVALAIFMHHIVVLSVLSVTSIIYVAKHPSIFRENMKTPLPDVDFAGSVINSNVVAAIFFGFSAAMLGITGFESSAQFVEEQKPGVFRKTLRNMWALASGFNTVLSFMVIGVLPIEEVYVKKDTVLAEMGRVSAGHWLELWVAIDAFIVLSGAVLTSYVGITGLVRRLSCDRVLPAFLMKQNPWRKTNHYIILLFFVVASSLVIALNADSTILSGVYTYAFLGLMALFSFGCMVMKAKRAEIPRDVHAPWWTCIFGFVFVIIGIFGNLLGDPKVLMYFALYLIAVVLIMMVMLDRVTILKLILAVMKSLFPSRSAENPTAEVDLSDRSVNSGGSGSSSLLDAMAQDARDMQRTGARGGRTITKTIIDINDAPIIFFSKYPDMTIINKAILYVRKNEQTSNLRVVHMYNDSVDGGVESGASMETRKEFENIVALFGHIYPKLKIDFVSLHGLFEPATVQWVSETMRVPTNLMFIAQPGDKSVHKVATLGVRVITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUA5</accession>
    <name>A0A8K1CUA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUA5"/>
    <dbReference type="OrthoDB" id="432686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="372" mass="41158" checksum="F362D2F0AFF72131" modified="2022-08-03" version="1">MATADYKLFTPLTLGKDFVLKNRVVFSPLTRGRSNQQTRTPNDTNTLYYEQRAGAGLIITEATAISEQGFGWFGAPGLYTQEHADGWKKVVDAVHAKGGKIVLQLWHMGRQSHSSFNAKNETVAPSAIGITEGHLRNAQGEHAPYEVPRALETDEIPAIVEDYRKCSELAKQVGFDGVEIHAANGYLVDTFLQSSTNKRTDKYGGSIENRSRFLLEIVDAIKTVWSSDRIGVRLSPNGSFGQMGSEDNVETYTYVFQQLSQHNLAYVALLDGFGFGYHNKCRLITVFDAKTHFKGTVFATNSYTRDIAEGVIRSGAADAVGFGRLYISNPDLAERFQNDWPLNPDASYADYWDASKGAEGYTTFPAYTPAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUT2</accession>
    <name>A0A8K1CUT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001219</name>
        <name evidence="8" type="ORF">Poli38472_001221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUT2"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035706688" description="Kinesin motor domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="432"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="523"/>
            <end position="530"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="637" mass="72328" checksum="C98AD9E2F7349B6D" modified="2022-08-03" version="1">MVKLFCAVVGVGSVFSVDIDISETVDDLKKKIKEEDPDMFSFGAARLKLYLAREGDTWLNSRDEDIKALKKGEIPDRIKSLMQEELLLDETARLDDDDYFRKNFQPGDRDIQVLVELPSAFGVPSIQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLESESPQDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNRLALSREMHGFYDGLSYEVPIMNIYPGKVDDKSSIANRYKGIDGRGWKRPPVYKSPGTATMIPQQQWRGEGENMDKRTARKVHADQFQSTIREIRAEYVKKASQEQPAETPDAEMASDQIHVYVRKRPLLPHEVEKHEFDVISALGEREIAIHECKMYSDMRHKYIVTHRQRFSQCYSEQTETETVYEDTTKRLVLHAMGGGKAVCMMYGQTGSGKTYTMGGMMDYIALDLFTENVGSVDFASQHTTGPSKHAGCNSAPLVHVLALAAPLLLRDHRCCAWRLVHWRPLPPSPINALAVQAFRMNDHHSTANMATFQPIKSLQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9K7</accession>
    <name>A0A8K1F9K7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UFSP1/2/DUB catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9K7"/>
    <dbReference type="OrthoDB" id="417506at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071567">
        <property type="term" value="F:deUFMylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48153">
        <property type="entry name" value="UFM1-SPECIFIC PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48153:SF2">
        <property type="entry name" value="UFM1-SPECIFIC PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="2">
        <location>
            <begin position="433"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="634" mass="68716" checksum="B816CBCACD00F932" modified="2022-08-03" version="1">MAVVIPSTLVHTLRRYGVADDAHGTFDDDASLVTHGVVLGTLSGALEAENKTSQVAVWGLVRDVDHYEQVTSYLPAGIAPVGVLAVWRRGSTAKFDDEDTERTAAIDIARASLAKSTSTTSRVALVFVHETQRFHCFQASEELTSLSLTVVESLHASDFLQATGHVLLRTALEVDEPLCLDTTELFFSFPEANAQVFSATGVDVTSSSSPSSTLVRSLVKVPEEKATKAKKAKKNNAYQVNDNWDTGSKVSKGANAQDPLAVAATDMPPYLKTLEYGEIANVELLHSLAPSSDAVLHAPFVDIPPVSSNEPAPVRKVLRIDALAVVSLDATVADAVQLLNSQVTQQARAAKPVEPHHFALTGVAFPLTLPVADGSVDASLATTLAHQFFQSATQPRFDSTKCSLVAQASYLATTDVLINVHEGIPSSGVVNGTQYLVDGFYGYYHYMQQGMNDKGWGCAYRSLQTLSSWLLLNHYTDKKPPTHKEIQRTLVQIGDKPAKFVNSREWIGSMEVGFVLDERYGVSFRSLNVSSGPQLVEHAQELKHHFETQGTPVMMGGGNLAFTLLGIDYNDSTGECAFLILDPHYTGSEDLETIQTKSMALEGYKGVPCGWRRATTLAKSFYNLCLPQRPQLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAK7</accession>
    <name>A0A8K1FAK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ryanodine-inositol 1,4,5-triphosphate receptor Ca2 channel (RIR-CaC) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polycystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="300855at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000086">
        <property type="entry name" value="Polycystic kidney disease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046791">
        <property type="entry name" value="Polycystin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003032">
        <property type="entry name" value="Ryanodine_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF183">
        <property type="entry name" value="AT14535P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20519">
        <property type="entry name" value="Polycystin_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02026">
        <property type="entry name" value="RyR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin" evidence="10">
        <location>
            <begin position="101"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="9">
        <location>
            <begin position="304"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Ryanodine receptor Ryr" evidence="8">
        <location>
            <begin position="956"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Ryanodine receptor Ryr" evidence="8">
        <location>
            <begin position="1069"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="737"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1164"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1212"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1219"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1233"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1243"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1309"/>
            <end position="1321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1330" mass="151917" checksum="BDBBF0B407C1F058" modified="2022-08-03" version="1">MNSQSPKTPEQLLADNLLQKKIAQYSTMRVHMKRVQLCLEQEKRNKFYKELLIYVVFLVLVMSSLLSLPVHFPYEQNAAMSDLFFDEEFPDISIRKTFDDIMIEDELWQWVQGPLLAGFYDLPTRNTRRIGSVLIRAGRVKGDLCRYTDGRSDFVLFANEFCYPEFSKHMEDTEAYGDAATSALKAKYEWDAHLGKLLRSQTFTPSLFNHEMDYGHGGYAVYLPRDNVTAAEKIVEQLKEDFLTDSTRYFAASFAFYNARSNIFTHVQALVEMSDTDYMETTARVKSFRIMPSYKDEGFYWANIFVVVLIIVTIWLIYRELVDLREYGWQHYIQSLWNLLDLLQLVLLILFLETWASYLVQGENIRDQLYQVARMDCNVPAHAQKIARDCFVDVEPLAWRFKSVTNYAAALALVSVAIVFKYLRLNTRLNLLWRTLRFAAKDLLAFVIIFFVIFFAYAIMGFLTFGSSVRQYHSLSVSLTSCFQMLLGAFDYNLIYNGNPAMAGLFFFTFMISVYLICVNMFIAIMSEYYSLAQAEKKEHEANQKLLATNGEHGDGKGGHHHNGNDCADGYADVEYDLLKQVQAYLRGLRVRVRLPPTKGDHNSFMYEQVLLSGYQRVLLVDYDYLMAERKRLRTKCRAAVQASLACAYLLRRVRGAEFKMQVEHKLLVDRRPRASSVGSFTDLAEFPVTYIPITSSRAKPVELLKSLKPGMLVDMDDGSLTKDQITLEVLGNQDAYIPPRYRRRPPHSQSFHDGAQDDTDDHLTDLQVPISETEDDNDDSRQQSSTSTAASPVFGPGRRPFGLRHDHEDIGSASHIRCCRVLYDGDTVLDGMEACLFPRRVWASYFLRHVVWGAIKRFFTFRHKKRRPKRLITDSEVDRLIKEYFVAPGRGISCRFDELVRNFRMLIAKKIHKKNLRISNSNLEDRIFVEVITFLERFPSALSPLDKRELEGYKYTPQPVDTSRVRIPNSILLLAELLAQNAHEVWAVGRIQQGWRWGPSRDNDKLLHPDLLPYEELTEETKQYDRDTSMEALKVISALGFVLQPSLSGSDDFDIEFGVATTEPGGTYEPRPIHTEAVKVPAHLRSLIELLAENTHEVWAKMRMDQGWKYGPRRDDEKREHNGLVPYIYLTQDEKQMDRNTAMQTVKAILRCGFTFVHKDKVSSSRATRKKHSGSSIRMFGRNENPEAANVGDAVTLARGAARAKRAFMKRGTGHSGFGQSSSRSFTNRTLSAASSASSQSGQPRFSQSESFGIDEHVLESSGSLSDFSERSESTRSLVLEPHSAPDSATSALAGATPTLQHSSTLPDRIDTTEEQDGKPPRPPRVSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAN7</accession>
    <name>A0A8K1FAN7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAN7"/>
    <dbReference type="OrthoDB" id="422427at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="205"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="46805" checksum="7798E217AE370C37" modified="2022-08-03" version="1">MAMEGFDLDAYAAKYSGRNRVNRLLFIAKHSEALRSGAHDALLRELKSGLNMKLYLEVAEAATAATEDIPESALSVDHAQVETVKRNAAQQHERLEQELNSYKSTMIKESIRMGYNDLGDFYYRLGDLPSALKSFAQARDYCTADKHIVEMCLNVIKVGLHMQNFGHVKSYLTKLEQVATAQNDPVLKSKIASAFGLVALNDKNYHEAALKFIECQVDIGSSYSEVLHAEDIALYGGICALASFKREELKDKVINNPSFKAFLELLPWLRELINDFYSSNYTACLQALENMKTEMKLDMYLSEHVHTLCQEIRSRGIIQFFYPYLSVDLHQMAKTFNTATPELEKEVCDLIGAGKIAARMDSYQKVLYAYHPNRRNATYKRAFEVGRKYAAESRNLTMRMSLLKNHLVVRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBB0</accession>
    <name>A0A8K1FBB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBB0"/>
    <dbReference type="OrthoDB" id="122279at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="392"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="808" mass="90275" checksum="47008B08A9293DF7" modified="2022-08-03" version="1">MRAKLAAQVCSTCFSAFIGVQHLLQMTGYARPIKQEGTSSSQNSSTQGPAILASSSQQSAQLQLPVLTPLSSSASYIYSSQPHTSRDQVDFQADASPSILPTSRRRPRPASQEAPPATRVLRAACVAELTFSFTGMIGTAMVIHDQALRENFHVVFWTIAPQRAAQVASFCWMGTLALYIAMRQRASFDVAVAHAVIWLLAILYWVLVVIAAYTRSDVVEQAGTVFWMVFAGSNWLLVTTCWAVFMRRWTQQPSRQRGAFVVAKLLSYVVAFLVFVTPIVILHAVIGVDDKDQASLAHTVTSFLMALWPTANAIVYLTKPFLFERCFKDTRETAVDQDIVIPWHANDGCVGRTDRFATATTSSDQSERSFRRGGRAMTQMPLSMTRHELKGLEVGEKIGEGMAVVYKGKWRGADVAVKMKSLMIDPDEDLDEFQDACNREIEEEAAVMKNLCHPNIVLFMEAGFYKRSICIISEYCSRGSLRDVLQRARGDQALSWSTKVRLALGIAYGIQYLHNSNPPMIHRDLKSPNVLVDDSWHAKIADFGTLRFAEIVSSVKRSTEVHTRASPSKPDQSMVMTGLVGTTRWMAPEVIRGDKIYTSKVDIYSLGLILWELIEGKLPFETTRWNHEIEDYVLRDIRPVIQGELCPMRWRSLIMGCWQTDPAQRPTIQQVITTLQRIAREETLDTSAPRITDITSFYSSNLSERSNTSFLGTSMASLSSSLASSNASMMHQDHRSKASRVRGREQNLSLLSVGESEQFDEGDEDVMLEMNSYFGDEGNFLTDDAVILEARHSDLEADDNDQKELIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBI1</accession>
    <name>A0A8K1FBI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="433309at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.300">
        <property type="entry name" value="mk0293 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1380">
        <property type="entry name" value="Transcriptional regulatory protein pf0864 domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00299">
        <property type="entry name" value="nickel pincer cofactor biosynthesis protein LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="NICKEL INSERTION PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566:SF1">
        <property type="entry name" value="PYRIDINIUM-3,5-BISTHIOCARBOXYLIC ACID MONONUCLEOTIDE NICKEL INSERTION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="Ni_insertion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="8">
        <location>
            <begin position="102"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="8">
        <location>
            <begin position="644"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="878"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="948"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1103"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="948"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1103"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1493" mass="167660" checksum="548AF2EB8FF64B55" modified="2022-08-03" version="1">MLTMAPTSARIYPVTYAPGPEDPDDIDTHVLGVNNIEKPADLPQIQEDTTPPPVLAVQQVQVKSSAPPKLVSQRTVYLETKERIGKLFERRDSKRGRLVHEVIFVMIILNTAVLAFETCDGQNRYSSAPGYAFLPGQKFYKASNHFFNVFFSLEFVIRNAMQRCKRRLLVNPMNWLDLCALLPWYLQLVLDASGFDFNVHGFAGPAHLVGRLQLLRLARLMFILRHYDSSKILFLSIRVSVPPLIITMFFLFTLVMLLATATFYSEPCYDVDTCPFTDIFNSAYFIMGTIATVGYGNQVPTKKNLTSLLIACIAMIFGQLYFAMPLAIVGNNFQDMYESFQQKKRRNMRQVDSTLSPFDYVLLNRKSQRLCEIQFHLLEAWRVVQLGILKFVRMSYDVNGVGATKELVEAQHLRYQKIKAAIERLMDVHMEACQHLNTFIPHKRKARTSVFMSQGDNKLSQVYLRARQAFAQTRFMSDEPKRTDPNTLRETLRGRLWLLLEAPNSSMLANVTNKIILFLALASICTFFFESLPELMNTGIASTACRSVVDDYCDGVGYASMSLLKPDAGCYLRFANKSVDFAKPLNFKCLSTNDKPTCYGAGYNFGSELEDALTCDEAFDKYGASIICNRLQCINTFTIFIMEPYWIYLEWFFGIGFLIEMGLRYYVSFHRKRFFFDLYNVVDVLAVLPFIFEVGEYAILSIQPTYIIVSTAPSFLSVIRVLKTMRILKLTRHFKGTKVLTQTAKEVWRQLTIPVFFMLTLCILAAAVYYEIERGTECFVGQECNWWGKNILTPELEADYPVGKRLLIQDTRYVLITDMMRSAWLSFGTFTTVGYGDIVPRTSIGKLFTILVALSGTIYTAMPFSLVGRKFTQLYERHRERNSTRRGGSSASWHAKGPHRGRASELPTNSVITSAPFKIKDEDVEAIRQFQSMKRTIQNLQRSLGNLNEVGNTSQRRQSNILNSPQNSGSALKTDSIERSIEEKTNAILDTVLQFSELVAKLQEAPPLFESIVDDDPTFTGSSEFERLLGIAGDMLLGALIDAGAPLGEIKSGLASITGIQGEWDLSTSKVWKGPGRIAGTKAHVSSVYQHRSAPVPGVVTDEEHHHVHDHDHDHQHGHDHGHEHSHEHSHDHDHGHGHSHDHGHDSHGEPMRNLGDIKTLVLKSELSEWAKEKSIAAFTLLAEAEAHTHGTTIDEIHFHEVGAIDSIVDTVGSILAMDLLGVRQVYCSALPMSTGTVRCAHGLLPVPPPATFRLMIGVPVCPAPKEAKGELVTPTGISLVKALVTEFSEPPLFVPTHTGVGAGTKEFPGHANIVRVAIGTTVEPSAQSVAQSGDSTPGQLEEVVILETNVDDLNPQVLGYVQERVLQAHALDVWTQPIQMKKNRPGILLSVLCTLEHERNLTKLLYQETTTLGIRRKVMQRTCLERRFFVVEAYGRKVDVKVGYYEGEVVNVYPEYEHCKEIASCEGIPLLQIIQEVQQQAKEQVDISARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCE2</accession>
    <name>A0A8K1FCE2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCE2"/>
    <dbReference type="OrthoDB" id="130864at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="30942" checksum="53DA4090333FF23F" modified="2022-08-03" version="1">MPIQTPYQPLTGRFTKLHLRRAKREYERRLDQGNGDIRVVLLSQTSMEFWHTVKISYYDDESLSVEARFFSNELINFYIAKAHNHLHWHPRMEISKQLQEYCSGNQLRVFTGSNQVYQSPRTGQYVLRRSELEIRPHFIANVEANPVPVANGLAWLREYFELQSKLRVAVHVQIFEREEARDNGFPALAVVLRRDEQDAVVVDDAVSFGSARLSCRTIEALKSYSIRELPLVLQGENPVNPWSGHHARLTISKADFFKREKSTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD01</accession>
    <name>A0A8K1FD01_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 19 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD01"/>
    <dbReference type="OrthoDB" id="160168at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00325">
        <property type="entry name" value="chitinase_GH19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.20.10:FF:000001">
        <property type="entry name" value="Endochitinase (Chitinase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.20.10">
        <property type="entry name" value="Endochitinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016283">
        <property type="entry name" value="Glyco_hydro_19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595:SF79">
        <property type="entry name" value="CHITINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595">
        <property type="entry name" value="CHITINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001060">
        <property type="entry name" value="Endochitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0611">Plant defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442139" description="Glycoside hydrolase family 19 catalytic domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 19 catalytic" evidence="6">
        <location>
            <begin position="77"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="140"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="233"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="29381" checksum="01FFC6F8F2B9662C" modified="2022-08-03" version="1">MKLSIVFTALCALAYGHDVASAYNFTDSTETTETANVPVEYETAEAPVEYETAAAPAATGISRYMTEAQFKSVFPNAIALYTFKGLVDATKKYPAFANSNDATKNKRELAAFLAQTAHESDNFKAAEEYNHASYPVSQYCNPSQVKCASGKRYHGRGPIQLSWNYNYNAAGKALGHDLLNNPQLVATDKSITWQTALWYWMTPQKAGRIIHNVVTKDDGFAQSTDIINGGLECGPSAPNKGNEQQRIKYYKTLCSKLGVTPVKKVSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD57</accession>
    <name>A0A8K1FD57_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD57"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="339"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="50666" checksum="479A2DE3884DDA26" modified="2022-08-03" version="1">MDMEMERVVDDGANAVDAADDAGRAQGHAGLRGIHSVSVRFRHDKRDLLATQHARYALLVRTVDRWRSVAAARRARREQLIAACRVGARFFQRLYWNQWKETLTRRREARERACARLQSLQSKIRLLRGFHRWKHVVEARRQAVSNAQSACDERRLQVQETRINRNDESGRRATCLTASDPSVRRLRQAKIARIRVYHTQRQYFQRWLEMVKNWSTVCDQRFKEQSRSFQLHSAVRRWRRRTEGRIRGRTMAKQAYFFLYFHLTSSALERLRRNAMRERRERDVAVTIETRGLNQHYGFQFPVRRQALSPVDQVSRSSPHHTPSAVPVFESDKDAIGSIMELEERLRGFEQRRQRWKRLQQSLEEFRRNLHDASTQGLLSSQELGHMKQRLALMEEQNSQYQKQWLASKPEIKSLAAQLSRLRRAVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDZ9</accession>
    <name>A0A8K1FDZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIF subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDZ9"/>
    <dbReference type="OrthoDB" id="76676at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001096">
        <property type="term" value="F:TFIIF-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05793">
        <property type="entry name" value="TFIIF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="236"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="519" mass="57284" checksum="C43C6AC5F53A32BA" modified="2022-08-03" version="1">MSLEYFRSSEGDVSGRLHERTVSSLALFSRELALMATSTSGLMRANGASARPAARVNGAQGAKEEETFVLRATPSIKRYNIARFDVPTVPKFSTCAQPVMMYREPEKVIEDEEEKKEEEIGYNPALRKRRRRRRKDTRTANWVIEDNEGKNKYVGAFEGGQSSMYCLFVKNRHNDEFSVIPVEHWFRFKKPLNYRTLTLEEAEELNNEKKRAVERWLMKHKMFNDEKTESNDVVGAPRVRTGAVGGGAKKKPGEEGGDIFEVKESKPRRAAPRPKKAAEGEAMGEDGGDFDEKFDDDESEAEIEHEDAKAVESESDDEDFGEGEGTGKLTETGQAMKDLLKRAQSGEMSADKEQDNETGEGSDEEYSAQDMDVIRDLGGNIIRGRAPAAAASGGDANANGGDKSGDANGSAKGNEATNGKRTATDDAPGQPPAKVQKTPPPKPVAPTASSAVKLTEAHVQNELIRFGGRMKSRDLLKKLKKLLQTDSDRALLKDILRTICNVEKDAIEGNLFVLKAQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE05</accession>
    <name>A0A8K1FE05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE05"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000286">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="36"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34506" checksum="BEF4974F33E78C70" modified="2022-08-03" version="1">MRMRSASYPEKMTLATPTATPFVVAMPAKKAVSATRVPKFLRCLYDILHNEDQSILSWSKDGTHFQIYNTKRLEVEVLPKYFKHGKFASFQRQLNNFGFRKWTKTQSNVCTFSHHHYVQRHPQQLVDLVIQHNETMAKSEAKGAAKQTQCVSHGKRKRSESESEACVVAKAIKKEVVSSPASGSFTNQRPASLPIANLSKIEESAFDFEVESWNVISDITPIVWATKPHVMIKTESGNETPTSVCGYADITFDFTIEEIDDILETTSSLADDPVLSSGRDAPVTTWEAELFKHELDVYTPDSDLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEQ6</accession>
    <name>A0A8K1FEQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEQ6"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="135" mass="14957" checksum="F154D46B112CCB7B" modified="2022-08-03" version="1">MAECSEALMTQFVNDLLDSEKPDFVAFSSDNVQTYRASLRQAAMDAATSGVEARGIPYAMIFGNHDDQRGFTREMLMEMAVSKPHSYSQRGPSQVYGVGNYELNVKAPTDGAWGDANSDVFRMYFLDSNAYPDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEV2</accession>
    <name>A0A8K1FEV2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEV2"/>
    <dbReference type="OrthoDB" id="68481at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="78090" checksum="73DE84578387A4A4" modified="2022-08-03" version="1">MPDGNEHNGSLFHVGDNVELWRVLMHLCIVVFFIIVFEQCLHYGGHHIRRYPKYHEMMTKVFGELMILGFISLGIKILKDVSHLNANGKPIIAFQAADIMVFILAIALIVQAVSIYVNLRSKNIQAAKAELISSAHLVIMIKEEQQKKKTLMSRVCALIPTHWFHRVRHIDKTTITPRDYTQITEARILRHFFLKTYKLPDLFPFSKYLRHAQDNQINHMIEVEISTWIILLLLGWVMMVVADLFEKHLTTMEEHLAVVAAFLVLSWLAVALHLVIYIYFWWAIRKLLETASGYMNATDKDLFAKLQEIAEAETLAVGQEVVADAIAVMLRVREAEQARIVKRRRNHLMKHDTGFQLVAMAWRNASLRLRMGKSSGTDSPVSSDAIAYSYDTEAGENWTSIPDPQLSSAHPSQFHIPFFSRKAWHFVVMSTLMLNGFYFALFCQCVMYQLGRIADHFGLAAAVFIPLPLIVNMLVFQPRILRNFILVSSIHRVDDTAMGEVIDLFTETMELRAEFVQCVNDHLEQSGQTLEDVHMEFLQLDVTKTGKVDVDDVRIVIGRFGFRLSFFRFNSVARLLFHLEGTQVEYNQVLKLLSLGRFRCMEPTSVDSKGDGYANASGSSRAICSPSHNRHVPFVRQASSTNLNPVLQRANSRVLRSFYRMDLSPDESEHRDESTYHFVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX4</accession>
    <name>A0A8K1FEX4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX4"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="192" mass="22087" checksum="83B281855BFCAEB4" modified="2022-08-03" version="1">MAPTPHTTEAADPSSTDTATLPEIKIRSYWADDHKQVLEVVTEGLMEYSKVEGQSLEFWNNYMDRSLRGDLADLEGIYFGSGGHFWVATTVEDGEEVVVGTIGLEAKADGEAKLRRMSVKEEYRRFGIGRQLVKVLEDWAVANKIRKVWLSSGFVMKNSHRFYRNLGYKQFKVEVYCEDPYFELFFFEKTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF51</accession>
    <name>A0A8K1FF51_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006453</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like Alba family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF51"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051958">
        <property type="entry name" value="Alba-like_NAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002775">
        <property type="entry name" value="DNA/RNA-bd_Alba-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516:SF4">
        <property type="entry name" value="FI09323P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01918">
        <property type="entry name" value="Alba"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Alba-like" evidence="5">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="33953" checksum="AB73A514DEB10051" modified="2022-08-03" version="1">MDKYRRVEKPKAEDETPVAPNEIRITHMGKVRSYITYANVLLADKKEKTVVLKAMGNAINKAVTVAEILKHRVAHLHQITEISSIETVDVYEPLEEGLDRLETKRHIPSISIQLSLEELDKSNPGYQPPIPVELVTPRDDDKEPVKKSVPKAKKPAKEKTAAKSDREEDEGEVKQGSAEDTKESKDGKASRGGNSKRGRGRAGKGKGLKDGEAKDGEATADNNAKEAGTDAPATDAVPKKKKPQRKKKPAADATATEGDSAAKSDGEAAKGDDGETREGNGGRGRGRGRGRGRGRGRGRSGRGNGGESNGEVVAAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF96</accession>
    <name>A0A8K1FF96_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF96"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="67" mass="7637" checksum="B68EC444B5E16E38" modified="2022-08-03" version="1">MMGDIVTWVDYKLLTPPLLPSLLVEIRLASMVLTELVQVALYHMCLVVVAKLAWILASDFGWEHLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG14</accession>
    <name>A0A8K1FG14_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG14"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="356" mass="39620" checksum="4C26B360C471F836" modified="2022-08-03" version="1">MADNQSFPLQARQQYAVETLRVNGTMTPAPRGGATLSQLENGEIYLIGGANRETHSFGDAHRFDFETKTWSLVVPERGNLPARSGHSAIAIGDEIVVFGGLDPTECIVYDDVHIFSTRTRQWRQPDVEGWMPQPRNAHAAIRLPDQDGQHRILIYGGSSPSHGAFDDLYVLEMSIEDRAAPLRWDRIEDKQSEGAQDEIPEARELHIATFLTDKQVCFSGGRNRDGSICTDMALLDIESWRWQLVPICEWNRCSHAAGLVDGTLVSFGGWNGGAITDDTWEYADNEESWLSAQITSPSKDEKDPERDETQIPERFGHCGCTIQPNKDSPTGLLVFGGMNGEQDLNDLVWITCVSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGD1</accession>
    <name>A0A8K1FGD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Osmotin, thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000129">
        <property type="protein sequence ID" value="TMW57673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGD1"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013">
        <property type="entry name" value="THAUMATIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013:SF2">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456971" description="Osmotin, thaumatin-like protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="46508" checksum="1AC51F6F54540173" modified="2022-08-03" version="1">MISPKFFCVALALLGSVRAEDEVVDRSVVHNSHAATSAAATRQVELYNNCGYEVQYKWTSGFNTPANAFFPIPSPGPNGYKLKTQERYTATFVNNWSGNIGACQGASCETGSACTGGCGVANAGPMTRAEWTFVPDGTDFYDITVINGVNIPMKMEPIGASYNTNDPYKCGIPGRIESVTSGSGCSWDYAKFQSDFHYNAVAGGSGKACSSASGCSGGEVCGYKFVPGVGLGMFCGVRYGFYTANQVCALDNGNSYFKCDQSAGDATGLKVRDMYGCVGPWYLSGYQPASVGQDGKVCGCTDWADRGVGVLPTPQTEKCKVKNPKWLEKIAPNLDFLKKACPTTYTYPYDDMTSTFVCPGEKKFRITFCPSGTTSTTPTPTTGPTPTPQPTQTPAPTPGPGGKYVYIGTSPDKDAMTQWCNWNCPAFCPPDMCRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGH8</accession>
    <name>A0A8K1FGH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGH8"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="4">
        <location>
            <begin position="39"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="165" mass="18343" checksum="84AA38E888CDFA96" modified="2022-08-03" version="1">MAGNPVARNSAEYVVAKIDDLANWSRESSLWPLTFGLACCAIEMMHAAAGPRYDIERLGMVFRASPRQTDVMMVAGTVTNKMAPALRRVYDQMAEPRYVVSMGSCANGGGYYHYSYSVVRGVDRIMPVDVYVPGCPPTAEALTYGLMQLQKKIKRNRNLLLTIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGN2</accession>
    <name>A0A8K1FGN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010909</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGN2"/>
    <dbReference type="OrthoDB" id="165345at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479382" description="Serine protease" evidence="3">
        <location>
            <begin position="28"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="56333" checksum="F443B6F320920C21" modified="2022-08-03" version="1">MPSFSSLVRGVALACAVASFLSTSVTAEEKGVTIGTIEDRFFSVNSSVARTPQTQTLTSSGSSFITVHFAHFELADGDKVVVRSPDNAYHFEYTGLGRGQLGNQGGFFSSRIPGEAAVVEYVPSSSEPTNAINGFTVDQITRMSRGASMLTVCGTDDTRPAKCYQNEAVVYQKAQAVARLLINGQESCTGWLLGSEGHLISNYHCLGGAGRSDSTDYEFSAESTSCDDECKVKGGCAGKVVADTATVIASDANLDYALVKLNTTADLSAYGYMKLRVAGANESEQIYIPQHPSGWARRIAAVVDDGSVAKVDKVDGSSPCGDHRLLYAADTQGGSSGSPIIATKDNAVVGLHSCGVLGSDCKNSATDIRGIIYDLKKKGAVPRDALDDPDAPVPDGPWIPGTTPAPTPSTTPAPTQSVCLVFRQQSTCETLLPGRCIWSNGACIPNPASETPTSAPTTAAPTPEPTTPAPTTPAPTTPAPTTPAPTTPAPTTPAPTTPKPTTPAPTSTKPSVCRVFWFKSSCEVLSFGKCVWKDNTCVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI41</accession>
    <name>A0A8K1FI41_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Formin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015">
        <property type="entry name" value="PROTEIN AD-016-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="3">
        <location>
            <begin position="20"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="4">
        <location>
            <begin position="1333"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="724"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="800"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="873"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="935"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1009"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1135"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1292"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1755"/>
            <end position="1814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1846"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2020"/>
            <end position="2077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="827"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="882"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="943"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1142"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1304"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1854"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1869"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1921"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1954"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2028"/>
            <end position="2039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2046"/>
            <end position="2077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2077" mass="221271" checksum="E5DB981A3711C8D0" modified="2022-08-03" version="1">MGNNASAGTSRYLTGCPPIPPQPSEGDVLHEFEELLRGKHVTMMVVEEMGAFEPTETKWMYISLNKFLATPEIAEKEWLEAHTCAHEIHEVEHRQEHHHELFRAIRINMTLRSREWIDKFIAVNGVDALSTLLDSSKKLPVAVHMEVVNTLFTLSNLNNGIVAIVQSSECCHRFVNTFSSSTNHALSVRVLKLLGVICCHSQVSQLAVISAFGASAPSGSSSRFSSIATMFKEQTSEPELQMAILTFINIVLNTTVVVGERVAIRDDLEKDGFVTELDKYRTPSDGAAPVSASMTMQLQIFQKSQQNDRAKASLTLELPTIDTSIDVAPRRESATSEAALSPSGAAQGSLSKDPARSLQARKSLKLNLSEAHTDVDAEPVPPAPSAGSSVSRRHSGQRLKLDLTDTNTDAEPVPPAPSAGSSLSRRPSGQLLPSLSIPSVEVAFEAPVSKTKPSIEIVSQPVAETTTQPVVPSFESILAKLQEGTQRLDAGTNQKLLQLLTTLATTLTTEAADGVKVVEQLERSLVEPAAQSDEAPSVIGKMNFRLLPTDGDSYANSLATPAKPTFGRAVGQLRLFGDSTLDHATSSTSHSPVNDAATRSPVHSQYEEESSPRRSMTETESCDESSHEYEDTTSRKTSGAKLALAGFFQHLKKGQALPTTPAPTPMATASVKKDAKRPVFPSFGTASAAPSPMPPSHANPHSFSLPPLTPLRPSLSLPPLTPVRPAMTPSKPHFSSILSPTPHAEHLESVKEEETESRSPHVSISLPVPPPPATPSSSGPDISKFRKLLAMGAPKAAVRAKMQQAGVDPDLLDHAPSEAPLPPPAPASAVPADAPAAPSGGPDVSKFRKLLTMGAPLEAVKAKMRQAGLDPALLDQKPASTPSAVQQPAQAEVPPVPTPTQESAPDEAERFRKLLAMGAPLEAVKAKMRQAGLDPVLLDRKSVSQPSATTSSTPSTPEPAAAPSVPASRKVKDDPEYVKFFKLQAMGAPAAAVKAKMTQAGLNPALLDTPDADMPGKSPSQPPAQAPAPVAAKVLVKDDPEYAKFFKLRAMGAPAEAVKAKMRQAGVNPDFLDTPDAEMPSKAEPQTASAPVQAKVLVKDDSEYAKFFKLQAMGAPAPAVKAKMVQAGLHPDLLDTPNAEMPSKGGEASGGASAPEAPKVLVKDDPEYAKFFKLQAMGAPAPAVKAKMVQAGLNPDLLDTPDAPVPSKGGESAIAPPPAPANMNAASALCNIFAKRQGNSSAGNNQAAESGPVVLAKDHPEYAKFFKLVTMGAPADTVKGKMLMAGLRPELLDTPDAPVPPAGAASNNQSSNNAASGPLSIPAPARRANLSLSIKPAVAKPTTRPFYWQHLKGEAIQGTIWEEIDKERSQGNNETPLPLSDSELALLENEFPAQTAPMTGPAKGRSFSMDSVGKEAPASPKVVFLIDRSRANNVSIIIKQFRMSHAALREAIMKVDAQVLTLERVQGLLKIVPTDEEVTAIMGFQGDILTLNEAERVLKELISVPRLKQRLAALQSKLQFPTFARDLQSKIEKLQSASTEIAQSAEFKTILLVVLQVGNKMNQGTARGGAKGFRLGDLIKLAQLKSSDKVSTLLHYVARMMRQKNGNTIRLSDSLGSLYDVQNIPIPELPADMSKISEIVDYITNEIGAQKLKNAIEDKEPCDHFVAVMTEFMESASQAQKTLKQDLDKLFQSLKDTMDKFGFGDGSGDSDPAEPATQGAGNIQATLQSACEFFATIYEFSNALAKADRENEVKRLREEAKARQSQKAKNAPLRSMSSRDIRANLAKPVEKKKESEEGAGPETPESSKSGARVSPLLRQRSASLSSIVENNTIICPDGALIKPPSHTVIAPVKSPSTNKPQTQSSSASIEKKTAGEKDREATLKEKTLTPTKKAEASPTGPETKEKKTSPLPTGIKPPTKFLKDKDKDANQDKDKLKLKLNPKPMLMVPGKIVKSTTKPVSESPNKDLPPPTPRKPTTFCAAEALSSSAIANQKVESPAVEDDSPFLAFDTASIEEIRSQLAMKHSSGPASTAKPSGSAQKEAIRGNNNASSSPPKTTENPATSCESESAPTTSAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FII6</accession>
    <name>A0A8K1FII6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_009192</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29535"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19518"/>
            <dbReference type="Rhea" id="RHEA-COMP:19519"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132517"/>
            <dbReference type="ChEBI" id="CHEBI:132519"/>
            <dbReference type="EC" id="2.4.1.260"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29536"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FII6"/>
    <dbReference type="OrthoDB" id="19039at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052917">
        <property type="term" value="F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF1">
        <property type="entry name" value="DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="57740" checksum="8265AF7353526759" modified="2022-08-03" version="1">MTLSATLMNMTLDAVDALVILVVSAHIALCPFAKVEESFNLQAIHDLLVHGVRNVERFDHIEFPGVVPRTFLGALAVAGITSPLAAIAKHIGLRKIALQVLVRWVLAMMNVTALLRFKQSIRARFGKDAARFFLLICVCQFHLKFYLGRTLPNTFALGLTLYAFAFWLEFKLKRAIFLFTFTIIVFRGDTAVLFAPVLLWILLHGGLSIFRVILWGIQATLSSLVLTVLVDSYFWQRWLWPEGEVLWFNTVQNKSHEWGVYPPLWYFYSALPRALLATALLLPVGVSVLLPALLKSRSFKQLRAAFTSAPLVDWSVATFVWPVILYLALFSILPHKELRFIFNAIPILNMVAAVGCSKLYHDRKKSLLPFLAAVGCLVATLLGSAFFFTASRLNYPGGEAFVRLHHVAYGERELPRTVHIDVPAAMTGVSRFGEEFEAWSYSKDESLLTAQDLVHFDYLLTAKDPELLRERFEVVDAIESFHHVQFQPFPPRIITEKSIYILRKCKVQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIP5</accession>
    <name>A0A8K1FIP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001004</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIP5"/>
    <dbReference type="OrthoDB" id="10069473at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="49030" checksum="DF5C8D405787FA1B" modified="2022-08-03" version="1">MDEFLAELRDLDETQERVEAVSDELLKALRSGNDDDGTLIAEMVDVWIETLRTSDFQSERIAFLYVANHVLQKTLFENDAKPDEAPRIVGLFRPHLEEAVSLVSNSPMDRQSVLRLLELWHEKAIFSDVKILEMWKCTGEDIPEFLAKVAAESDTDPQLAPEAASEHVEDVEADLEQTPAPALPKLNARAANPVLNALKKIDRQKVAIMHLEQSIRDQHSFILTQAPTRYSTPQDLLDDYTTPVTLMKQRVEDCLRLVKTRNRMMQEIPVLKEELKQALAQMIADEKAAKEKNEQRLEQCDMIDIGLADLAEHRDTYPDEWSQEAYTSLERQRRREEEQRLHDEKMARLHQAALAESAAHAMNLEADITGEPTSELRSMAKDYHESTQEAEEEKPQQTNEMVWHPVLKELVPLQSLNLEWESWRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJG3</accession>
    <name>A0A8K1FJG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Striatin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009058</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJG3"/>
    <dbReference type="OrthoDB" id="727118at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="302"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="410"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="452"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="505"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="57458" checksum="175CFCE2B34DEA19" modified="2022-08-03" version="1">MQMEDAHGYERLVKRVEELEERCRGQEAAHKALVLKVQQLEQLLQEKQPKLAEPAPVVTVEDSTKSLRGGLKKSSVVEGSSRTVTMRPPERVVTFHPSLPSPAESPKAQTRASCSGSGSFKALGSPRASTAPRFDAQARQSSGHRLSIGDSFHSQSQKNVKPQPLGLVTKAPFRPLKLKWKLLGHMDGVRSLSYHPTEPMMVTGGEDCTVRVWKIVDTTHGLASQRPSELDSILTLRAHTASVLAVSLVGLSHSSSSNNRGLLASSGRDGTICLHKLPQLERDTAEPRTFEEHHSFLSSRVERAHDDAVWDLHAHPRSPILFSAGADGVVKIWESGPEGLTAKSELRSVATHHRHASGHSYHDNLVPTSVTSVPSDAKSCAVGYTNGGLALFDVANGQLTQMVRPKDAESNGRDHQVNRVVAHPTMPLVVSGHLDRKIRMFDLRSGECIATIAAHLSAVSSVSFDSSGQYVASGGHDGSMRVWAIAERQCVFEQSVHRPKWAEAINSVSFHPTQTSVATAGADGLVKVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKC9</accession>
    <name>A0A8K1FKC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKC9"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035448623" description="Peptidase M12A domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="220"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="401" mass="44026" checksum="09EC1882D2474CDF" modified="2022-08-03" version="1">MLPHRVVLLVLASLALIGTSANTPAKANTAVTSTARGKAPPRAKPLAVTSSKPSAAKLCTVAGQKFTAMSYVKGFPAQPGSVFAVCTKGVPKCYLDDGLVDVIQRKEVPCASVTANATATATAAGPVTRPKSRNLGLYRENQFMWPQGKVCYGFQEGFTLSPNQQAIFQNVIRTYRTIPGVPEGHLDIITLDECHRRYKPTNRAHTEICGDCQQLVRIKGNEDGCFGHLGYAVPGNARVMNLGADCHDEGTYLHEFGHSFGLYHEHQHPERRVVILREGLGMALDQYAVTRLTEQEQIQIRRNFAIPTYAEQTEYDPKSIMHYQSGSDLCSPAFQHPHNNPRLRWCDVFETKEEHGCEVPRESDCSGTQPTLGGEVLSDGDKAALLLMYPVEQEGNESGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKF2</accession>
    <name>A0A8K1FKF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70398at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1104"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1135"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1173"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1212"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1241"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1340"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="72"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="762"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1366" mass="153212" checksum="C2051B4204F9292F" modified="2022-08-03" version="1">MTDIRPLQPTIEYTSGKEFMKYGSEELHKHYSSRMETALGKAMHQMEVRFHNVSVSAELAMAEKSKTNELPTLYNELKKTFGGFTAKKNHVTKHILKDVSGVFKPGTMTLVLGQPGSGKSSLMKMLSGRFPDSKHITKQGEITYNGATTDEMKKRMPQFVSYVTQRDHHFATLTVKETLEFAHECCGGVQFSDRLEAILNKGSPEENKAALEASRAMLEHYPDIIIQQLGLDNCQNTVVGDAMIRGVSGGERKRVTTGEMQFGTSLVTFMDEISTGLDSAATYDIIKTQRSVAKNLRKTVVIALLQPSPEVFALFDDVIILNDGEVMYHGRADKAVDYFRDLGFACPPRRDVADYLLDLGTHMQRQYQVDRADGSKHPRKPSEFAHVFRKSIIYDEMMAYINGPHDPALLQDKDEMFNLVPEFHQSFWPSTKTLINREFKKMSRNTAFFGGRVAILLMIGLLNASVFWQVDSSNPQVVLGVVFGSVLFFGLSQSAQMPVYVADREIFYRQRAANFFRSSSYVLANVIASIPVSIVEALLFGSIVYWMCGFFSSASAFIIFLLLLFLTSLAFTSLFFLMAAAAPDLHVAEPISMVSILFFVLFGGFVMTKDQIPDYFIWIFWMNPIAWGVRGLAINQYRNDEFDVCEYKGINYCDKYGMRMSEYSLSLFAIETGKEWLWYGVIYLVASAIVCMSLAAFVLEHKRYEGHHNTTLDDEIEDRPFIPVSDSETEDNQYALVNTPRREVAVNINASSYERRIIPVSLAFRDLWYAVPDPANPKEELNLLKGINGFAMPGKMTALMGSSGAGKTTLMDVIAGRKTGGKIKGQILLNGHQATDLSVRRATGYCEQMDIHSEASTIREALTFSAFLRQDSDVPDSAKYESVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLIMDGVRKVADSGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGKDACELIQYFESVPGVDRIEDGYNPGTWMLEVIGAGVGNTANQDLDFVELFNRSEKSAMMEEKLAMAGVGVPALGVDAIEFTSKRAASELTQAKFVIKRFMDLYWRTPSYNLTRFLISILVALVFGLSFLSIDYNTYQGINAGEGMIFMTTLFIGAITYNSILPIASDERASFYRERASQTYNALWYFIGGTIAEIPYVFGSTFFFVLIYFFMVGFTGAERFFLYWFVLSLHVLTQAYIGQWLAYTFPSVEIATIMGVLLTALFFQFMGFNPPSSAIPSGWKWLYEVDPPRFSFTSLSAIVFGDCSSSENTTELACQKMLNLPPTVPAGLNVKEYVEEVFLAKHDDIGINIVYMVVIIIFFRVLTAFALRFINHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKX0</accession>
    <name>A0A8K1FKX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002198</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKX0"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF3">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="545"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="65371" checksum="EE2D3DD850E88B43" modified="2022-08-03" version="1">MINHGNAMATSSPFPDEFEYPPPGHGVSTSLQGLPSSSVRPTLDAYYHHGQQHHGMPQQQQYSQPTPTHHAQHSLEAVTQHPYYVAPQPAYMQHYASTPAALASSSSLKRKMTAVVANVATASSPPPFAQDKLCDLCQHADPILYAPNCGHLFHSRCVNVWPLHHCPACRMELDKVSVLRIDMNEQVESRSGKWTRAEEKFIEVILQEFDRNSFALANGTPVRLVLAKLLNCSTMRLSKKFQKNALGKRTFRIPKPAKGIPAMEFDREDHVVRQKEFSRLEAIFRHELVEQFRRENNTDEGAYVETQNLRKAVKQFWVANFLKFAVMVGQAVEGLDVSDSKKKKLAFQMLRDGQYDELLSWHLPAHISSGYPGDHGAHPGAHWSNSGAAVSMGYPTVTTPTMQHDGHHPQKKQRTPETMARLQMNTEMPANQFSLPGSSASSYEYGRGPVGYNAPYSSSVGYEQNAYGQYPVMKQDRSPVSYEEMAHASQHHAPVQPHAYGASSHVMPPYDGRGVSESASMVHPVYHSTQTTTSLPMGHGEASYQAVQGPSSGSSAQSWDGLLDEMAPGASAPSSSVSDPTMQAWSNMHIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL47</accession>
    <name>A0A8K1FL47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009041</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL47"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="335"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="366"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="705" mass="79240" checksum="0C22EF43D9C1F700" modified="2022-08-03" version="1">MDTKPATVMAPVPDARHDSWTADRLAQFIANAISGVVVVTGIVLYAVWSASVQDQTYRFFMQLSVNRHMSSCWDHKAAGGVIAFAECLGVIDVWEEDTDADILDSFMRQLSRAVTLTSIACGVLFLASKYKSIGWYLWLQTVTIIQWIFALYQVARITISASTYFTIKTVKVLAYAGQHLHAQVFRFRKKHATALRQVMKKAKSYAEWVNMARNLDILEDKEHWKADILPEDQEHCDFHQLQKNMDDLRQAIEAKNIDALKYILTSFVMRNKVGIDAADLHLECSSGTKHVIEQYNSLVVDALKLLSDASPDLFPPTEKTMFFRKLKQSFGSTALCLSGGGAIAMYHMGVIKALLQADLLPNVISGSSGGSIAAAMAACKTNEELINTIIQRDISTRYYHHGIWWFPPLFKQLVHCIKTGFLVECSDFERTTQHYYGEPLDLPNKHMYYTFQDAYLKTGRHVCITVSASDVTGHKGPKKLLLNHINTPHVLLWSAVAVSCSLPGIMKGKKLMARDHEGNVVPYDAMGKEWVDGSIQHDLPMETMASCFNVTNFIVSQVNPHVVPFMGEDVHTPGFRKSIFHTLESVIAADVRHRLKMLAFLGLFPKIYGHQFSSYFKQNFRGNVTLIPDFIFLEAIGVKAIVNPTREDMDRYIVGGQRAVWPKLAYIGHLCGVEKCLDACLASLLPEDVATQARYSNWFHPRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC7</accession>
    <name>A0A8K1FLC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-glucan synthesis-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC7"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000157">
        <property type="entry name" value="Beta-glucan synthesis-associated protein SKN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035430318" description="Beta-glucan synthesis-associated protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="714"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="742" mass="81982" checksum="D7E3C41E3E9D022C" modified="2022-08-03" version="1">MARVQWWRLFSVATALLTAIEAAEFSTKSGLRPWVDPDTPEDRQAYVSSRGDTWELVMSDEFNQPERSFRPGDDHMWTSLEKPDGVNAALEYYSHNMTSTLCDDNGTCYFYIKVMEDETVLRVWNDYQDVPGYKTVYFYYRAAMVQSWNKFCFQGGMMEVRAQLPGAVTPESGNPDIKGGPSARATTKLYYPTWPGIWMMGNLGRAIFSASTNRMWPFSYNECDDSVFPSANQRISACDPNPGSGMNPYQGRGAPEIDILEGGGTDISSSIQAGPGMPTDFRAIFPKDDDNSGCIYDYNCVTKGANGPDVPTKYYMSKRGHKSWYQGLRYAANNFCQPNGKYKQDYETVAASVKAGITVNVCDLETCAGSKDANAEIGLIDGVGPAHWGINSNGTCYPVMNAYTGAFLCSPGNPDPLCDQSKKVPANDKLKPFAYQMDAISSNWPVHLGAYMDYMVYQLEWVTGSDGYVRWMLEGHPIFEIPASAIETPPQDGGNTNPKKVMLEEPMYIIFNVALSTSWGARPPNPEKPCRGDGTDEAVNMLCDSFPMYLKIDYIRLYQDVTPGSKMTTTCDPETHPTRQWIQDHIDEYQDVQNQVEEVNGMGFCRTSDDCTVGNATLSRIQTGSCVKSRCKCNGGSWTGPRCTSTLGSTQASSTDDAIRSIFQGSYGPSWASAFIVAGLCFVFTILSVYMAQKREKAQDAEFKKNMAVQPKSAMSIASPGDAGFKEPKDNMASGSRPGFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMW0</accession>
    <name>A0A8K1FMW0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMW0"/>
    <dbReference type="OrthoDB" id="165498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="33"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="27546" checksum="7A21E1E83E2F2CD6" modified="2022-08-03" version="1">MAHAEERALYDATTASTTPKGAESDARDDGGYDVVLHKGVCGLGIYFTASTDGAAMVDPHVPFYRLPDGALAPGEGSGCIAPGDRLVAINGKDMRLCAFSMVVEELRQIPKGAVTLRFEVSSTQADQGKSTVDTETESVNAVVADVEKDESKPPSSRWKLFDSRESHRQTTSAMETLLVKMETKLRDMEMELEREKKCRFLAEKKNILYRNALRSVGDENAQLRYQLKRANEDTQQLERFQHKLQLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FND6</accession>
    <name>A0A8K1FND6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FND6"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09253">
        <property type="entry name" value="AP-4_Mu4_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14838">
        <property type="entry name" value="AP4_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="187"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="50742" checksum="749DCE14A81237E2" modified="2022-08-03" version="1">MQMSSISQFYILSNRGDTIIFNDFRGDVDPKSAEIFFRKVKFWENGDAPPAFNVDGVNFLYVKKNALYFVATTRYNVSPSYILELLTRLCRVFKDYCGVLSEETLRKNFILCYELLDETLDYGIAQDTSTEGLKVHVHNEAILVGEAAAAKPASGSKFMTRSSNIKAASAVKKPVATAAQGSKKNDENELFCDILERLNVVFSSGGQMLNASIEGRIQLKSYLSGNPELRLALNEDLVIGNTGQRAYGQLVLDDCNFHDCVQLDEFERDRVLIFQPPDGEFTVINYRITGDFRAPFRIFPFVEEQSPTKIEMLLKVRAEMPENNYGANVIIRFPVPQATVAVSCDIGKNAAGQLAEYRESENQVRWAIKRFTGGTELTLRAKITLSQPSPHVRREIGPVSMNFEIPMHSTSGLQVRYLRIPEHARHPNYKYKRWIRYVTQSSSYVCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FND7</accession>
    <name>A0A8K1FND7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">BBSome complex member BBS5 PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012330</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
            <location evidence="2">Centriolar satellite</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BBS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FND7"/>
    <dbReference type="OrthoDB" id="10261999at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006606">
        <property type="entry name" value="BBL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030804">
        <property type="entry name" value="BBS5/fem-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014003">
        <property type="entry name" value="BBS5_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21351:SF0">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21351">
        <property type="entry name" value="BARDET-BIEDL SYNDROME PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07289">
        <property type="entry name" value="BBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010072">
        <property type="entry name" value="DUF1448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00683">
        <property type="entry name" value="DM16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BBSome complex member BBS5 PH" evidence="10">
        <location>
            <begin position="32"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="BBSome complex member BBS5 PH" evidence="10">
        <location>
            <begin position="162"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="39290" checksum="07E194499232B3D5" modified="2022-08-03" version="1">MEIKASPESITWQDREIRFDVSAAAMEMRKGEVMIDSINSVEDTKGNNGDRGSLEITNLRLLWASHKSVRTNLSIGYNCIQTIKIRTATSKLRGNTQALYVMTKYANSRFEFIFTSLVKASPRLFTTIQAVFRSYETTKLYRELKLRGAIIKEKELMLLPHEQVYTRLNGVWNLSSDQGNLGTFFVTNVRVVWHANLAENFNVSIPYMQINSARVRSSKFGPALVIETSTASGGYILGFRIDPEERLHELFKELQSLHQVFSTNPIYGVEYEIEEKPQSLEALKQPRKVDDVEIEEDQSSSIDAFAAYYAAVNKNQDRPPLYSKDLGLAIESLPDGFSIGDLWFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNK2</accession>
    <name>A0A8K1FNK2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNK2"/>
    <dbReference type="OrthoDB" id="168308at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="154" mass="16404" checksum="271608054995FEA9" modified="2022-08-03" version="1">MVKGLMRQSVHPMETIKNDYSASQTASPRNSSNDTLPHRIADDTNDPKSPRGKAMDDQVDPHMTPGPGGGGRGREDEYDKGASAGTQDNTDVISGMGSDQQSFNRTGKVARRLTFADEAGGALAEVNYSNRTHYSKQTSQSALPGTGRACCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNK6</accession>
    <name>A0A8K1FNK6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_001652</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNK6"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000005">
        <property type="entry name" value="Mitochondrial phosphate carrier protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="49"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="146"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="250"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW69496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="37213" checksum="70763149A8FDFA71" modified="2022-08-03" version="1">MSAFFPVISSLNPAMPKAPVKTQARPSILATSAAKWDARYSHAVPHDNAYYGKCMIAGVLSCGLTHTAITPLDVVKCNMQVNPAKYKGLVPGLKTIAAEEGTAALFKGWAPTAIGYSAQGFCKFGFYEYFKDLYSTMAGEENAYKYRGLIYLAGSASAEFIADVALCPMEMVKVKVQTSPAGTFPTEFGPAVAAMRANAAETRYPFGSVVPLWSRQIPYTMAKFFFFEKVVEAFYTYVFTEPKSSYPKSTQLGVTFASGYLAGVICAIVSHPADSVVSLMGKAENKGKSIGQIASETGLKNLATKGLGTRIIMIGTLTGLQWWIYDTFKTVFGMGTSGGAPPPKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNV8</accession>
    <name>A0A8K1FNV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UDP-glucose:glycoprotein glucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_004037</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27683at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003980">
        <property type="term" value="F:UDP-glucose:glycoprotein glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06432">
        <property type="entry name" value="GT8_HUGT1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040497">
        <property type="entry name" value="Glyco_transf_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040694">
        <property type="entry name" value="UGGT_TRXL_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040692">
        <property type="entry name" value="UGGT_TRXL_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18404">
        <property type="entry name" value="Glyco_transf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18401">
        <property type="entry name" value="Thioredoxin_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18402">
        <property type="entry name" value="Thioredoxin_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06427">
        <property type="entry name" value="UDP-g_GGTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="7">
        <location>
            <begin position="50"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="8">
        <location>
            <begin position="335"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="9">
        <location>
            <begin position="478"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosyltransferase 24 catalytic" evidence="10">
        <location>
            <begin position="1339"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1620" mass="181259" checksum="DC24AED74F43D208" modified="2022-08-03" version="1">MAMTRRSTCFQRLVTPLLTLYALSHVALVCARGINVNLTATWPSSPLYPLLETSEFLAEENPKLFWRFVDTLAAHKSAIAKKSEDADALTQFAVDLAQEVAPNTKNILELTVATRMYSVRVEMFRQLGLDSGSRLCGPDAEAWAVFYQTKRCVTAVACSPDEITAALATLESDSSQTCLAAGMNDVELEVDHKYPQSGDVTKSTVILYGLIGTSSFYKFHDEFASLAKQGEVTYIARHFPKDAPLGTALQGYGIALDIKNMEYKTIDDSKKANEEPEAGEEEEDEFDTAEDDDEDTEAEEDVDGLFFSTLIKNHGEIEQEIKEFRDALVQQHDQEQDIKAWHLKNIGIAAAREILDSKNPLKRLRVLSQDFPKHAKKLAFSRKPLSDELRQEIELRRTEAVQAGLLDRFLINGIAINPTQRSFNIFDFMEELKAEWSVAKKIAALPLDVKEREEMLAHVRETKQESGAARIRVRGAVDGTAPLYLNDIEADHMSAQWSTNVGNLRQHAWNLIFIRKNMYEYVIAFDPMSPHGRTALKQASFLRMRGAPLQWGFLVSTKELVAARTREDRAAIVEQYKLASLGDKATGWHFAKLLILVKSKEKDVEPDERGRIVTAFIEGVADEPGDISVQTLIDCYVDATGGSLGHGENKKEALGVLHGDLLDEEAMSMTEYIGKKHLPFESAWFNGILKNDLDLQSDIMGLFGRDQAAYQAMARNGELTNDMDLVEELLASQGAYPAYFTLFGAGANSNSENPAQKINHIFASDEDGNLEALVTKHATFFHQPDTITLPKKQTLLFTVDLGDRVHAAHVYEAVKALEEDLGTFMRVGIIHSASTERQDGVGELVAAIIEAVGHSDVAAQVKLVVEALACVVKGKSLEATKSKLQGIIAKTPAWEADKLLPRITTLLSESTSDVILRSDVKASLKSLYNVILGARGKSATDATAHLYLNGFAIDLPEHPISAEDVVALTSYDMKHRSQPVAKAFIKRSVKYTAEEANARSMEILKASAIMDAYRKAERVSPLDHNESSIAIALPGDESLRVVAYVDPVSEAAQRMSSLLVMLHSQLNASVELLPLPASDYSEFPLQRFYRYLFDKKPSRATSIRFRRLPIKPILTMKIDTPEAWNVQVHQTTEDLDNLRVDADSPSDVRATKSASFQLESLLVYGQCRDKTFDMYSPPNGLQLVLERDIGGVHLHRDTLVMKNLGYFQLQATPGVWALHLARGRAIELFEIVSFETDESLPSMDIIVGNFGSRIEQLLVRKRPGMEEEELLAPTDGSKTEKASDVEAISPDAGAIGSYWNSMLSMFGKKGATKQQEQAANDSAVVPTTGANAGRTGETIHVFSLASGHLYERFVKIMMLSVLKRTKNPVTFWLLENFLSPDFKHSIPALREKFGMDIRLVTYKWPNWLRQQTQKQRIIWGYKILFLDVLFPLGVQKIIYVDADQVVRADLKELWEMDLQGAPYGYTPFCDGRNVGFQFWRQGYWKDHLRGRPYHISALYVVDLALFRQIAAGDMLRAIYDQLSADPNSLSNLDQDLPNYAQHQIRIHSLPQEWLWCESWCSDESKERAKTIDLCNNPKHKEPKLDMAKRVISGELFPESWVELDQEIRDAEKTFVLPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQH5</accession>
    <name>A0A8K1FQH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQH5"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF70">
        <property type="entry name" value="OS05G0316100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="38210" checksum="DAECFDF8C9AA7384" modified="2022-08-03" version="1">MGLSTLELAGREQSDTLLKHAESHSGAIKVRGKSMDHESEPLNGSSQHKTEREHEEDEEDSEPLEMSSTTKKYGYATAIAMVLITLYSIPTASSGKSVQYVWWCGWMTAVATGLGALPFYWIQDVNKYWLGICNGLAAGMMLAATGCLFYEAWFIPQHVEYAVSVGYRLFVGAFLGVLFIKFTKLYLEDYEDVKVCGLKGMDARKALLIMAVMTLHSVSEGIGVGVSFGGEGGVRRGHIVTLTMAIHNIPEGVAISLALVPRGLSVFFATLWCILSSIPQPIFAVPSFMFVEQSLPILPAGLGFAGGAMAYVAINELLPESLEDTKSLPSTISATSLAFMVFLTIQLVLSGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR04</accession>
    <name>A0A8K1FR04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR04"/>
    <dbReference type="OrthoDB" id="165690at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="4">
        <location>
            <begin position="76"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="485" mass="53830" checksum="4C2972048AEADEC5" modified="2022-08-03" version="1">MLWELWENPDYDRDLEPSELKRQACQECGSSWAEVGCKLCGKHYCNDCEAEVHALLVKTEGDPSGNLEAPHRQSLTPCNVCQGCRTRSVQLYCKDCKNYQCEECCASHLANENMRSHAWFCVEGASTSVTRYSVWHPSFTEYAKMCRRNRLKAMEAGDVKPKSSASIEDSVDEAPVPSEEDNTSHVNDRNTVEAETAVQIKMERVRLNDEESVKAPTTSPIEVSAPGKAPVKIEPQLSVLRHGRDSDIVDLTGDDDDDEPTVPVKGESRSSSSSTQSSWVSSAAVEPTAEEAAYLAASDEDPVLSVNIGEYNRMSEAIHRVDQQLVDLTRQAAELAADPNANMHAMRQLSHQQSQLKNLLMKEKHARNAVVARLVVFMTAPPNALAALLSSTSNIPDAQSACHRNCARIEASILDKKRRVIQLKRDMNEAITMKSADAFAEINRIGESIATEEASIRRLQADRLEEFKTLCRFSQQIRMAAQAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRK1</accession>
    <name>A0A8K1FRK1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRK1"/>
    <dbReference type="OrthoDB" id="195966at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34894:SF5">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34894">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE RSMI, CONSERVED SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="671"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="824"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="872"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="306"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="946" mass="107765" checksum="576B519D35C8750F" modified="2022-08-03" version="1">MILSTADTDKINAWLRSLQRERHQFSSYFLYCEMIFRESETILRGKSVPNRLQTALAFHCLCQATSVFGRHEDVLRRICSDLSAAIYLNHEDLPLHENNIEVLEYFANQHTYYDNQATLRKQKDDIQRELRHQALKYEARMKDEEKNIAKIKDLEAHHKLRELDKVSHRNTSYQALHDKLQIVLHSFKFMDEGQKQKIVLGVIGALRAHITADTLIAITEDISALEKEKLMRSLFHEELTSMTERIRAEVIATSSAQQNVILERSAARITRFQTMIWDRLRRDSVLGTISEPGESRPSTAVDDELCEQDRKVLESINDVMEELQGEKKKTADLEQRLHEAEQMINDLRWKNNVQMAEVHDTMIKHAKEVQELREEFSKSASATVEKEVQTDRSGDGDGMYDEDNGVGSNGKSRGRRRGGATDDDDDLIIKNRRLNKYGLGIASIIEDARIPSSKIRKILSKRKPLTLNELHAIIVGYYQAKMLQDIQDDNVGKGRSNIAQFIMDMYTLHYGLKDLAISQLVFLDASIRKHAAESARVRTFGLLTGCLEPDSHACSVQAIDFFLFVVVVMFNAGIYKKGRKQSVHVAQNLKVFFGEGIFMSPKSVTLKSEVVCTTIDLVFSFTRNEPGGKLDRLKDEIRLICSNQTTNVNGGIEVDMALEKIMNYWFMLYEQHIEDIHAMFTHVDTNNDGILDFREFCEVAQALEPDMDRREVLSVYNKAAGDDHVIDKDEFVQVMLAHQRGVILKEFYRHDSSKKVMFGIQQRKQTYNVSSSGEKTPVLQHSVRDLQYKTLSGAMAHLDREESYASLVAAMSMVTDALQPLVNAPLDDDDQAEDSPSTPQSEGERMQDNVSFVTLSRLSLWASEAKCKLSMSRHPTERSIPEEKEEELFTPLSTPSATHRPVPRSLEPPSTSFEQDINELLEQALAKANIDLQEVIKSPESGSLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSB1</accession>
    <name>A0A8K1FSB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSB1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="314"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="347"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="522" mass="57688" checksum="BC38223E71A880EA" modified="2022-08-03" version="1">MSWWHTSTLRLRSAERSVAGRVVFVVNVSPGTYANQENQEQVDRKSSSVQGATARSYSEFRSLWRSLLRATSSTTLFEEDTRRTSVYDRLSRTSESWVAISRRVLGTIDKPGMFSSGRCHCSQDQCPFDRLHVVLKDYPFPRKKLLLTQLDEYALERRRQELERFLLTIQTYFRGFALAFLDQVDSCEVLHLLNAFLGIDEGARTSVIASPGANVTDSNRLSTPRGSLAPDSTRNARHLPQLQIKTIDVDTSRASWAGRFSTVFDVIGSRVMGSMSSGGDVALALYTASTRGHCGTVVELLDRGADPNAVIGDLSSTALHAASHNGRLKVVQVLLAFGASMNEADARGMTPLMSAVGNGQVQVAQFLMRAGADLSRCNTQGESALHDAVRNGSVRMIRLLLDQGADVNVQNARTGQTPLHIAAVTGNLAKCRLLLGYKADTELCTLRGRKPINLAIEGRHKSVIQLLEQHEDPEYTLHYLHDERQTQMMESSVDPEDIVYDMTPPQDIELVQEEDGATYAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C268</accession>
    <name>A0A8K1C268_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase</fullName>
            <ecNumber evidence="15">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_013816</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="15"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C268"/>
    <dbReference type="OrthoDB" id="151490at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021536">
        <property type="entry name" value="DNA_ligase_IV_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11411">
        <property type="entry name" value="DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="17">
        <location>
            <begin position="358"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="689"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="908"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW55054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="986" mass="112921" checksum="02BA2BC7033995C3" modified="2022-08-03" version="1">MQTRMNPHETKSSMDTTQQRAALQLSFAALCRMLEAVERTPKSDDKLKLVFSDALRQELQGGDIYPLMRLLLPQLDRERTYNLKEKKIAKVYVDVLGMASESCDAQKLEHFNDPTIVQSKSVGDFAAVLYEVLQYRSLVGNNKFQHTVGVVNELLDQLVRADDAASRRKVFMRLASEFPASEQKWVIRIMLKDLKIGLRHERVLNYIHPDATEMYNHTNDLHKVCVDLRNSEIRYVPKIEPFQVFSPMLAKRVDFGECTKAINSDAFVMEPKLDGERITCHYQADEVQFISRNGVNYSELYGFSMAPYVKSQVIPGVDVILDGEMMVWDNMDYRFREFGLLKNVANGLRAGESSHRWLCYVVWDVVYLGGEKANQLIRQVYNGPGELNAVMGLPLHSRRQLLLKILKPHDHRITIIDQTLVNSKSAKERHEIVMAEVDRQVANGGEGVILKDINSHYMCGESSRKTKKWIKLKPDYAGMTTNLDVLIIGGFYGTGRRRSGNVSVFLLGVLARSLDDNAAEEATKPGASVPMIYTFAKVGTGYNLEELEQMRRDLEPHWRPWDNDNIPAHFNGWRPQKSDLKPDVWIDPRHSKILEVYGFELTFTTLYQTGLTIRFPRVKAIRHDKPWYQCMSVQDLNTIRGSIFNKRAADVALGQKKAIKRVSKRVAISRGSGDIVAEFSQAKLDGVEVRHDIFAGQEFCVLPGKYENTSQFEIPGEILAKDARDITKQVIEKLLHSYGATIVQNPIESTNFVVAASDSGFKVANLKQQGRFNLVYLHWVLGSIHASRLLPLKARDFVYATDSTRSLLAKEYDRFGDHFTDLVSPDELKLLFREISRSDKRVFPSSKEQEPWQERMKELAVEDEDAMESEFTCLAHCVVYVDQYYSFHTPEFEKRDDEVDPFGPMKLLTQQIRLFGGQISHVVDENVTHIVLDSRDNQARIEQLRPIIRKLRRQSMKEPPTVTKAWVDECVKQRVQLPVDDFFIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2B2</accession>
    <name>A0A8K1C2B2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2B2"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="26171" checksum="806B274D5E4657B6" modified="2022-08-03" version="1">MELHVRVVSARNLLDTQTFGTQDPYCKVKLNKKDYKTRVHDNGGVTPSWNEKFEFHVSDPQSDKLSIKVKNTGFTSSTLIGEVKLPVKMFLSGEIIDQWYSLSNDGKRAGEINLRVQFVGGQAPAPQSYPPQGQHHEYQQQPPQYGQPQYGQPQYGQPQYGQPQYGQPQYGQPQYGQQPYYGQQPPHGAVYGQPMVVEHRRRGSHSSSDSGDDAGAVVAGAAAGALGGMVLGEMLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2R2</accession>
    <name>A0A8K1C2R2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2R2"/>
    <dbReference type="OrthoDB" id="114792at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033644">
        <property type="term" value="C:host cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032801">
        <property type="term" value="P:receptor catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019076">
        <property type="term" value="P:viral release from host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008187">
        <property type="entry name" value="Vpu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00558">
        <property type="entry name" value="Vpu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="12810" checksum="F3B9243167E8AF62" modified="2022-08-03" version="1">MHELVLVKMMVTMLCIAILVTIIIWTYRYIQYRRAVRLSQMRWLHFEADKIFDDTERSLNWPTAKPIMLSPIPEEHGRESMDSLASAQRDRRVHTASFLSYGSFEHAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C374</accession>
    <name>A0A8K1C374_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010512</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Probable methyltransferase required to silence rDNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
            <location evidence="1 13">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C374"/>
    <dbReference type="OrthoDB" id="10258825at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000068">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 13" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW55630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="284" mass="31643" checksum="3AFAF77693137B10" modified="2022-08-03" version="1">MSRKSKKSKANGAKNSAGKPPAQAKQGKKAGGKKQQHAVVKGASKATQKPQQGGKGGKKLTGLSKMQEEMRRRLDGGKFRMLNEQLYTSTGKEAFKTFQSDPELFDVYHQGFREQAEKWPVNPLDTFIDYVKKHPKAIVADFGCGDARLAESVKNKVHSFDLVSRKPQVTACNIANVPLPDKSIDIAVYCLALMGTSIREYVLEVYRVLKPKGILKVAEVKSRFETEGLGGIAGFVAAMKRMGFDLQHKDEANKMFALFEFVKTPRKPEDGVLIEFKPCEYKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C396</accession>
    <name>A0A8K1C396_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C396"/>
    <dbReference type="OrthoDB" id="4866634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF33">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="645" mass="72979" checksum="F5698E2E2E967FF6" modified="2022-08-03" version="1">MVVITFYLNCCVFPRDTKQYPRRLSRSAWDLTKGGDAIGFSGTNDNHRLLPLGITQREPNEPSLRATNGRMVDLLRVNTREYSVLSGEPFNVNESVKSSGNTLSVWQSLLRLACDEKCNALIDTGALLAGVPTYKAAIFLAKSPRLPESVAGITYYDTRKTYDCWVVLERTKKLVTPLKSSPIHERDTFVIFDEARSRGSDMKLLSDACALLTLGPKMTKDKLMQGAGRLRQLGCDQKLWLTSTKEVERSIRQVTGCELGPIGVMQVLQWVVESTQQQCTLGLLEWGQSGIDYCGKESDSKLESKDDDWSLEYLYGGARSPMKIATIIQDRVKNSSAAGDLLKVLEEVGKHGNRYGREDEVLVTSLSEECEREVQEEKKIQVEELELGGELEPLKEEEWNFEQLFRANAVKDLGSDAGIDSMKVKSNTYFKSLIEVDWNQANLYGTKNFWKTVEQPDSPPELRSSKHLRTIDSLVVFKDLCVLLLTRFETDAILKLLRTHRLQDTGCFRLVQLEFLFGAMRRCHDKALPLSDVPLSIGYPTREALSDVVLPSAVMTACRLFNGDTDFLSKSHPQLTEKTLRLLLDSMQDREKTLREFIEECRSPQRWNRSWLHELTVEMHYDEVASGQKHVILSLPNENEATKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3A6</accession>
    <name>A0A8K1C3A6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3A6"/>
    <dbReference type="OrthoDB" id="123860at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457316" evidence="1">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="104" mass="11687" checksum="A3A9EEF5CA40711A" modified="2022-08-03" version="1">MKLLGLVLAALPCTVDGLNMDNPSAQLSRRRGPGRGGVYEVSFSDAEESLLRERQGDTLEMISRVLNGRNVNEIQRRCIELGLRCGAYAQLLAKNTENWRRRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3F0</accession>
    <name>A0A8K1C3F0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Translation factor GUF1 homolog, mitochondrial</fullName>
            <ecNumber evidence="9">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Elongation factor 4 homolog</fullName>
            <shortName evidence="9">EF-4</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">GTPase GUF1 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ribosomal back-translocase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010617</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3F0"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001496">
        <property type="entry name" value="Translation factor GUF1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="78"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="156"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="677" mass="74768" checksum="B6B7AB912453A6DA" modified="2022-08-03" version="1">MSMLQRHLVRGGALSRRHSAIAKKAMRPFHPLLRALSTSTEDATGKARKKEAQRDALNISPTTLGPFMTTHLAAFEPENIRNFSIVAHIDHGKSTLADRLLERSGNITKRDRENAQHLDNLKVERERGITVKAQTASMVYVDKTDNNKTYMLNLVDTPGHVDFSYEVSRSLSACEGVLLLVDCSQGIQAQTLATYYAAKERGLKVVPVLTKIDMPHAQPDDSILSLSSLLDVDPDDVLLTSAKSGIGIDDVLPAVIKRLPPPTADIDAPLKCLLVDSYYDDYRGVICLVKVFDGSIRPGDKILSSHLKTKYEVQETGVLLPHRHKTPGLHAGQVGYVIAGMKTTSEAKIGDTFYREHAPVAPLPGFQEARSMVFASMYPTDECTFEDLRSAIEKLTLNDASVTAQQETSGALGMGFRCGFLGLLHMEVFHQRLSDEQNVQVLVTAPMVPYTVIDPQGKESVVETPGAFPDSTKYYRILEPMVEASIITPVDYLGAILSLAKDKRGVQTNLVYLEDGRVVVTIDVPWQEVVTNFYNELKTISSGYATLNYREIEAQQADIVKVDILINGKVLDALSFVCHRSKATVEGRALCVKLKKVIDRQQYEISIQASLGAKIFAKERIAPYRKDVLVKSGKVVGGGDSTRKKKLLAKQKEGKRRMKTVSNVQLSQDAFWSVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W1</accession>
    <name>A0A8K1C3W1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3W1"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPRY" evidence="1">
        <location>
            <begin position="255"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="406" mass="44457" checksum="2AE7392D8977323C" modified="2022-08-03" version="1">MVAASTMAAAATISPCSNKLRTYIVLNRKSSLGRLASFTDVLDDPMAKNEIPDECIAYESYAAVASRFHPSSPQRELRWSDLNRPRLHLASFLSQSNKKPLSQKARKRQVRRAQSSGNQNEHLVVHALELCFEFLDISDLARATAVCIEFRDVVMGSSRLLLGLYARKWSNKEYMAPKYYGADFSSALAMYQGRRKNFEYELSTRSQITKLSNGTYEVYNDSLLRSFAHGAIDSIRGVNPLPALSCALALQKRVSYFEVTMKGCGSVGMVSLSEPASCKAYGYGSDEHLGWKGVSFGYHGNDGDFVYNDGSAKYGGEWKPFGPSWGGMNTQSADGASVYTIGCGLNMATRELFFTLNGKLIGVAPVTVPVGDYAAAVSLHEFHDKAIVNAGSAPFQFDVEGYCASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Z9</accession>
    <name>A0A8K1C3Z9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Z9"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="655" mass="72901" checksum="8237C2A6C9B1259C" modified="2022-08-03" version="1">MELVDQMTAAMSLKEENPPQERVSSETVRGFEEEELALQLATTSDEGDDEGTRKDTASLVVALFCDGFVCRHFTRKNGWIEGFAQSYDATSSYFLQSLERGLLPDGLDELVETAAPKGEVVAELWDYRPSPAALCPLTSADLPRSEPEDVEGVTEVHIKRLHVRARNPIVLAEVPKANLIPTSDKFPQLSSADLEVLTNDELSRLALDTDTDLLQVDASIILLDPDSISVSVVFEECSLHGDTSSDRVSSPSDTNNGPASVDVSADTEASEVDLVTPKRQPEVTNPNADAAFPLLPPLTFLSPMEFKTMRATGRRTRNARARSSSPTDESHNQTDLPQSEPSDSDQSESAEVTDEWVVKRSMPSGSEEDDDNVTVENHSTDEDSRRPRSPGYRVSSRHNYHEESPMSRFEHTHEPTLVRLSLSPDVCDEINASVPRMRSFSFNNDEYAVDGNTSPPRPRSRSFTTPLSATHLFWARMRGKRRRNYTIDELHEGSPAWRMIKHMNRFYQSAFNFERRHAQSLQVNIDRIMKADNAAAKSTKLAAGSIGYLATQLHDFRNPVEVIAAANISKDLGATDDAMEEATTIRPPEPIRRDVENSKRSPRTPRLSTKSSPTGRYIANFIMTDTYDVDESSGIRQETSKPKPKSSLDGMTFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C475</accession>
    <name>A0A8K1C475_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purple acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C475"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488318" description="Purple acid phosphatase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="170"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="50345" checksum="2AC9EA21955354CA" modified="2022-08-03" version="1">MVFQACRSLLLLTAFVLGQTQAATQFHLSLAGDGTSDYFLDWVTPKVANETAPASQVYVGSSPSTMTRAIAGVLNGEVEEEPGQYVNCWTARLTDLTPNSVVFYSLNESAPSNPGQGPVFGPMPGPTESVRLFVPKSASADLTWSVWADLGSLIQGGTAGVALPALEQAALHDKSFDAIFNLGDLSYELTQTNGKDYMDRLEPITSAVPMHVTTGNHEYEHALAPEYTLRNYNRRFAGQFAGMGKASGSGSNEFFSFDSGLIHFSMLNTELYGNDLYVKQDDKGEWKEYDDTEREKDSKKMAEWFEKDLKQVDRQKTPYVVVTSHRCPFKAPKGLDKKSNRYGDEIVPLLAKYKVDLLLCAHTHLYLVLKESEWKGNRIPPTIVSGAPGNADGLDVLEDLKLGDFKVEFSAKAFGYGLLKATEKQLEWKWGSTGGLDAKPTNWTEVHQYSIPRAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4B2</accession>
    <name>A0A8K1C4B2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4B2"/>
    <dbReference type="OrthoDB" id="167638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="49742" checksum="A5F31D846D43DCE5" modified="2022-08-03" version="1">MVVKKLVRRMFGKDNSIHHKLRKAVAQGKTRQVAVLLDEGASATWMEEGMDDKDMNALLVACHKGDVEILNLLLDSFFEKTQLLRMWGRHMYCVVIRNGHWKAFQRLHERGVPLNPSGNLRSRLPAPAFIAAEHGQSGILEFLLKKDASEAAVYTFNGHSLLSIASKRGHYECVEILLAHIAVTSDMLDFALDCARQRNQAHVIVLLTSCLPGYSSSSVNSSSSSLYSSGRKSVVRFDSDSKERKSALLYHRRSSQCRGSLAETDIVSEAGDDAPSSSSTGWSGWDVEVYHPPPQPDSYDYYGDDNQSLYEQYLRSLEDSEIQDWTTASPGSAATGAELDYYLAPLSDPDSSLDVTLSGTWYYRNEVILPYDEEDEQEQGQAEDDGSVPLSNEAVPPVPAFAKSFSPIVTPRSSETLYVGAPVIRQVSRKIVSIRSNTLKNYRSVTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X2</accession>
    <name>A0A8K1C4X2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glutathione S-transferase 3, mitochondrial</fullName>
            <ecNumber evidence="15">4.4.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Glutathione peroxidase MGST3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">LTC4 synthase MGST3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Poli38472_006488</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione = 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione</text>
            <dbReference type="Rhea" id="RHEA:75963"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:85236"/>
            <dbReference type="ChEBI" id="CHEBI:194498"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:75964"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>leukotriene C4 = leukotriene A4 + glutathione</text>
            <dbReference type="Rhea" id="RHEA:17617"/>
            <dbReference type="ChEBI" id="CHEBI:57463"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:57973"/>
            <dbReference type="EC" id="4.4.1.20"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:17619"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Lipid metabolism; arachidonate metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; leukotriene C4 biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.20" evidence="15"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X2"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004464">
        <property type="term" value="F:leukotriene-C4 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.550:FF:000004">
        <property type="entry name" value="Microsomal glutathione S-transferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0564">Palmitate</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00069748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00075145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00076908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="TMW56478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="16029" checksum="03BADC918D725900" modified="2022-08-03" version="1">MTFPVMQPEHGYVVLLLAPMTIIHVWAGMKVVKARKLYNVPLPQMYADKDNKHAREFNCVQRAHQNTLEHMPLFLATLVASSLYRPGLAAMFGLIRELGFIVYIRGYSTGEPKKRMAGSFGYIAMLGGFVLTVEAGLKLLNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Z4</accession>
    <name>A0A8K1C4Z4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Z4"/>
    <dbReference type="OrthoDB" id="75502at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="216"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="662" mass="72537" checksum="45AFD696C0E4D955" modified="2022-08-03" version="1">MMESFGIDEFGREHFVVEAARGRLGISLGEDGHGFVVVRCLDVLTPKELEGWEPSDRHRVELLREVLQEGDRLVEIQGEDIVHCSLAEVISRLSKLSAIKRHLTFARYHSTGFDTKKYDVEKLVLARLPRGPLGLQINECIPYGAFIEDFQLLPDGSMSRLAKHPKIHRGCQIINVNGVDVTSMSREEVIAHLSTLRDQDKEVVFYRTARRTCSSIYKVESSASERHLGFTLDENESVRCVVTSVGPRGHSSISPGDVLIGVNSTDISWMGRKESIEFVKDTPLPRQLIFVRLGEQAIPECHQISLASGPLGVNLDGQEPHHAKITGFTTPADADQPAFKSCSSFLPGSFIVSIGKLDVSTHDLASISGMLVKLKNHPKQIVVANTPLLHILAGEAPIQRVKVPKGPLGIHFDSSRAGAAVISGYYKLQDDKVGEVEKTSRIPVGSTLLRINGLNVSCLTLEETLGVLKKLSDKPKELEFYVDDSAQDINTKTVDIRVPPGPLGIDLKSSISNKEATKEEKRDSVTKPIEYMINMSSWTGSRSLYRLLVDPTTRSLQITSAKPSTPKSGKQSASISVAFSEIVSLDCGKGARFSSQSSPSSSRSLFRSSSSTLNTDATDRANVCISLSSSKKSIEFDMRSIDERAAFAQHLHAFLPALVPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U3</accession>
    <name>A0A8K1C5U3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002929</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U3"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="1" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="375"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="524"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="601"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="568"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="678" mass="76490" checksum="52E67AE82977F9F7" modified="2022-08-03" version="1">MEPAAQNSLIDESTDPVKLSRGRVPFGLAGWKAEIVPATNRVSLKVAEHERQLRLAQAQRKHKYMVAPDAMPRYIWDLLMALITILLMWRVPYTIAFGEGTSLHWKIFNKSTDLIYILDVLVNFRTGYNVDADVVMDPKKVAVRYMKSWFLIDLIGSIPFELFVGNHSSGIERKAIKASVKYMKIPKLFRIARIIKFVQKYMKYAYTVQCLGIYLSVIHWVACLWADHVFDLAAFENNEAVAYGEALHVSVMLLMDISSVPVVREDYFICAVLSIIGFVFQSITIASITSVIMGSSNRAVQYQEKVRMVMSDLKALQVPVELRKATKSYYETLWRMKNTSDRYEKAIYEDEDLSPALRSEIALHIHRSLIATVPLFQDCSDSCLACVVMKLRTQLYMRGDVIFHKGEPASSMAIVSRGKVKVISPDNGTLLAVLKQGCFFGEMGLLRNMTRSCTVISATFCELKSLMRKDVEEVFDLYPQIYERLFAESEKRRLDTRLKAKIYNVKVLDNAHAVDVSCMDEVPHDDGSTSPKPFIHGLSEAESSSGSKPKLIRMNSLNADDGAIFNELDNMNVNIEQLQRLLDSLRNAQAKLTKVHDKRHSLHQALSKSSQHLPPMPTMPSKPTSPSATPILDEIRTHTTSRIVVPALDGHGGEVTRVTTLPKLVSRSSRRDSMLDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C669</accession>
    <name>A0A8K1C669_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C669"/>
    <dbReference type="OrthoDB" id="63070at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000733">
        <property type="entry name" value="WD40 repeat-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051859">
        <property type="entry name" value="DCAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847:SF7">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="328"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="62141" checksum="324EECB3C94D2E33" modified="2022-08-03" version="1">MSDREEEEHAPFASEDSEDSEYVEGEDEEAMYEAMGDEESEEGDSENEEEHEDDEPEDEDDDEQYDEFWVPSSSEDLHQVLPEDIRATVERVFAGQSLMPMRFVRTEQERKQKQNLPNERIAHQLRGYATDEGRAPLAAQRMSRNSKGKQVYYSLCLREQSGWNSKAQMVKLQETFMPFSKNKFCKVVDAIGERLYCGGFNSTGSRFLVAGQIAQILVYDTGNWEIDALPPARQVQWTVTDAKFTPDDESILYSSITSNVRMVSVDYKKTGREEVFSLLPAMERGGYRSRFGVWCLDVNASGTEFVAGTSSNSVVLYDMETRTPVCHAQGHEDDVNAIAFVDGPLHSNVFVSGSDDSLIKLWDRRVLSESNPKPQGVFPGHIDGITYISSRDDGYYFISNSKDQTCKLWDLRKCYSESEHARLPYYSRPYRWDYRFQEFPGLRKPPVAHPHDKSVMTYRGHLVMETLIRCHFSPLHTTGQKYIYTGSADGRVYVFDTVTGDLVEIFAMKPDGLTRDVRWHPYEPTIVSPDFYGKLCVWQRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C707</accession>
    <name>A0A8K1C707_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Intraflagellar Transport Protein 57</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFT57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C707"/>
    <dbReference type="OrthoDB" id="423881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019530">
        <property type="entry name" value="Intra-flagellar_transport_57"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011">
        <property type="entry name" value="IFT57/HIPPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10498">
        <property type="entry name" value="IFT57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="275"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="46386" checksum="0DA2BA58322F2009" modified="2022-08-03" version="1">MADDGEENTGELKTQGEAAPRDDVAVTLMGNVLEKLRILGYEREMGKKKSFTPYTETQFAYLTSNASAQFKSFLELVVFLMKQCNQDFVVDKYDDPNTSVNKLILALKVMGFPLDFPASKLKLGYGEAACAALDFISDKALSARNFAWPRPSYPKEDFADEADVDDDAEVDGGDEGPIGEEEEELYSDLVRANAEDTALVESYQQMIVSHVDPLLWKTELERVGPKLKLTVNEDDGKEWHTHIERTRKHETSMKDLLPRANTQLRLIATQLIETIQRMSAKEKLINNKYEHLRQEYHQIKDRLQAVSDRCKEEADKVNVMTNEYATITEQLRETKTVMDERGSKMTDTSPLVAIKEALKTLNAEIKNFELRIGVVGHTLLQAKARQAASGMRRKGDYQDPEMDPSDEDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C743</accession>
    <name>A0A8K1C743_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C743"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009313">
        <property type="term" value="P:oligosaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000006">
        <property type="entry name" value="Chitobiase, di-N-acetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051887">
        <property type="entry name" value="GH18_Domain-Containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46290">
        <property type="entry name" value="DI-N-ACETYLCHITOBIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46290:SF1">
        <property type="entry name" value="DI-N-ACETYLCHITOBIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="1"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="41941" checksum="74BAFEF4A5905F31" modified="2022-08-03" version="1">MDMRAFPSSAESAKGYLESCPCASPSWCLPVALGPRGNETKKPEIFAFSVETDDRWKYYDWEKVTTVAWNVDKELMCHAHSKGVKIVVKHNFDDTDKLCDAGARRQWIQDTYEMIVSNYADGVNIDTEKPMYGNTARCQTQLVRELRTELNRHPLTRHAQITFDVSWAPRGVDGRYYEWQAIADVVDFLFVMSYDMRSQIYYQCIAAANSPLPLVRQGLEEFIKGFGIAPSKLVLGIPWYGYQYACDSYTPDNDICTIRAEPFFGAPCSDAAGKQINYGDIQRLVRTHGNSSRRWDALTSSPYLVYHDANPDTVIQLWYDDEESLRAKYRLVKELGLRGVGMWNADTLDYAEDLVGSQRMWDALEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7K1</accession>
    <name>A0A8K1C7K1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7K1"/>
    <dbReference type="OrthoDB" id="120556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="33532" checksum="555E62936B907891" modified="2022-08-03" version="1">MRPWLTTEYVCSLANISCAMNHITGHQDELQEILGNMATNELQELIISDCIELEMPPRLQAFPNLTRVVIYNSSISLWEMDAALTADHHAKLASLSIIETNMSAVPPALLHSNLPPYMLDLVFSGTNLTALPSNAHEYWTMVSLLCLEVSPGVTEFPSTLALFPLISQISLVGNSITTIPEDVYAQDRFFIVTLDLSSNPLSSLPSVLDPHQFPLIRITNSDVEYLPDTWIDLPEIAPIILASGTKLCAHIEANESVFAAENSIVPVLNGPQWYSVQAASVCCEVESNGTRWFGNVDYTTLTTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7W2</accession>
    <name>A0A8K1C7W2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7W2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="129"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="49140" checksum="335186D240A6FA35" modified="2022-08-03" version="1">MSTKIPLTPINDAYGGYLATVKVGEDTQDMPIDLLNADIWIKCGVLPHLNTPCSTSWACSPGTSYKKQDGHLFCSSVATQDVSIGDVQVTNGVVNVLQHASYQDTPPESRLGLAPTDDNDQTAALFKKVNSLSLSLAANDPFLLFDGVDQSLIDKEGLKGYTVPTFDSLGWYMSLSAVKFGDSAAQMPCQLQDYYSCVGAFVSRYEYVSMDAELYADFKTNHLSSANCDYTSSERTVCDASANFPRITIASGSKAFYLDAADYTRPSTVPGKVDMLIEEAKANNVWGLGLPFLKKYYTHFDHAKNEMTLYCHENKTCDTDVLPVLDAPPTYSDTTSSDLWGGYGNDYSTYTLPPFTPSYPSDSDTDYNTGGGASVGIVYTSHRSGRQTGVYIGVGTGFSVLFMVIGFLKFVSKSTTPEEAKPEESAPIEGESSQTAYSSVSTPKAVAPQPQASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C828</accession>
    <name>A0A8K1C828_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C828"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13384">
        <property type="entry name" value="HTH_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19397" checksum="D59DE6BB7CAFE92A" modified="2022-08-03" version="1">MTAMPLPSFQTFLESTRYTLPQMTQHVVSVTREQSLSPMAKYSSKMYQLAVLTAMEYEKTAFVQSSPVAIRRALSPASSYEESNVTTSSDESELSDEERRASTGRRTVMPCRTKKKYLKERQRYEIVRRVRAGEKQAHLAKEFGVSRAAVCYLLKHQLEILSRSGASERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8I5</accession>
    <name>A0A8K1C8I5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005108">
        <property type="entry name" value="HELP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03451">
        <property type="entry name" value="HELP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="537"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="638"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1296"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1489"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="2111"/>
            <end position="2134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="2344"/>
            <end position="2381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="941"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1106"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="956"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2381" mass="259226" checksum="0BF1854255DD693C" modified="2022-08-03" version="1">MGQLHGKAAYAQAATPFLNASEKDVNKLWEAFNDVAEGFGLNQDEMCEICRSLMPTLEIHAKIDMDQLTIPLFNAFDTDENGLVDALEFLGTIAIMSAMTIRQKLTFVYNCYDFNESSQISIDELTLALRSTLTGLCKLSSGVLCPTELVLEDMALHAFHKAQKHGPEDYLILAEFLKFAETTPEMTSWIDYFDSPGELVETNDRDDSDLEVESAIHPLVAGPDGISDDLYALKVRQRDPGFPQDAKAPYFYQDEPAPAQPWQAAVPNAAPSAPPTLNPNAPAAGLELDWIYGFNSDLRNIVKYVTPAEIVYPAGNVAVLYDVIEHKQCFVFHHSDLVQCVAVHPVNRHIVATGERGAIPKIVVWNTNTLGSTLSAVRGFHRQGVAHLAWMPNGRTLISVGQDAFNCVAVYQWETMASASTTSTTGNTASIEWNKPPALIFTGRCGREPVHACVVLSATQFVTSGRRHLFFWARESDERYTSEHALFYKRPGVLGRKAKVQTLLSLAPVPGDASMVLAGSTRGQILVFEGRNCIKVLYAHATAVNVLQAFPGGILSGGKDGKIRFWSKRLEPGAQFDMEALGSISSRVRSLVPSPDGGAKLLVATSGAEIYEIAASDGSNLHFGAMLSGHFAYELHGLAMHPTKREFCTTGDDKTVRIWDMNARRVVRMALLDAPTRACAYSPDGSLLAIGQGAPEDAELPPDRLAHAVKRLNHSKQGAFAVLSEATLAVKYEAKDSKKYIRNVRFSGDGLTLGVNSNDAFVFLYNTDDWASKGKCKARDTSAVLSHFDFATTGEYILANATNKGEMVVFESASGVEITRLATVKDVEWLTTSCIYGWAVQGVWPTTATASRVSAMGRSTSAGNNAPLLVVGDTDGRLRLYRYPCVSPQALAYGVAGGSSALARVSFSSDNQFVVSIAQEERCVFQWRVEYEEEDFASTLASDGLTPLGPTALTEYETHPTSDDEAEESRGEARTPFQEAATAGEYALELLEHKQASEVSNETTTVPAAVPVRPWVASAVAPADAPDEKDSELSSVPHESLELEWVYGYRAHDARNNLFASRIKPWLVYPAAHVVVILDTKLWLQRHFKQHTDEVTALAMYFGNGKKKSTSHPTTTTGEEDEEGKNEAMSGYKTLELVASGQMGVSPVIHVWRVDTMEVLSSLRGFHRHGIAELRFNPTGNLLASVGLDQQNSLAVYDWASGILLAHSVTGIAPGRVLGLAFEQDTHASMLCTVGVKRITFWRLSGHHLVKKDALLGKKGVLQSFLAVVFCGKDALVGTTSGDLYRFKGVELASIVPAHTRSIAALYCVPKSPFHVVSGGKDGLVKLWSADLECLAEFSEFNTSKYAIRSVFWDFDKNKLVIGTRGSSIHQLSSLDGSQILPKTSDGLEITTIEAHSYHELHGLGVCPSKERFCTTGDDAILRVWDFTRHVQILAKSLDTASRACAYSYDGDFIAVGLGSGATGKRHKKDGSLLVFEDRGASVELVYETRDTKQSINVVQYSPDNQSLVVGALDNCVYIYDVPNNYTKRAVFNKHKAWITHIDIASDSQYIRSNCGAFELLFADITTGSHVASASALKNQQWETCSTVYNWSNQGIWPSHAAMAAQIQITTSAASVPGSSKELSGAVLAAGTSHGHLNLFKYPAFVKGAGYKTYVGHHGAIARVGFSGQANGAHCLSIGRSDRCIFQWRKTRTRMAYGQDDSAATGNASVVKDLDDDPDMLREGMFIPEAFVNLPPAEIKPFLSAIVPPSSETPEPTDAGGVAQTLNFELDTVFGLRSADVRNNAAYTKTKHVVYHTGCLAIHYDRRIHRQQFYRGHSRPIVSLAASRDGSVVATGEICGQHLQSERPRIHLWDGASCSSLAVLSAFHARAVSYLAFDTSHKLLASVGQDEFHSIAVYQSATGLWSDAALLASSRTTRQPVFFVCWVDDVSASPFHVVTGGKDHVTFWRLDAPTLVATDGVFGTKAQQQSVLCGASIGALVITGCLTGHLYVWESGVVTRAIPAHEGAVYAIHATSEGCVSGGKDGHIKFWSKTLTPMVDFSIHDVKPAPQSAVVRSLHWDLAEDRVLVGTKGGELLEFSRVTKDTSLVTESHFDHTELVAIDAHPQRPELVVTAGEDQTVRVWDLTRREVVVKLTLDGGLRSVAYSTDGKWIAVGFGSSTGGPTASGANKDGAFVILDAVTLEILHEGRDAKQSVLGIKFSPDLTLLALGSADHCVYFYSTLDNFALRFKFSKSSGKVLHLDFAADSSALRINSDVYELLFISTLDGTAITTPSSMKDTAWHTQSCVFSWPTQGLWDFAKEDEYVYAVTKAHSLPLLVSATNTGQVRVYNYPCLSKHSEQHILRGHSMNVSNVVFTCDDSRLVSIGSSDKSLLVWRVQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8J1</accession>
    <name>A0A8K1C8J1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 2-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_010096</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Microtubule organizing center</location>
            <location evidence="3">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ARL2BP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8J1"/>
    <dbReference type="OrthoDB" id="302784at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051457">
        <property type="term" value="P:maintenance of protein location in nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038849">
        <property type="entry name" value="ARL2BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15487">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15487:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BART" evidence="13">
        <location>
            <begin position="37"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18932" checksum="BEE64E17EE80830D" modified="2022-08-03" version="1">MASTRAEQPEVTDALKVEEEEEIFCDDAGGNTDESLFDEMIGVLQDILIDPAFVDLQTDFCLNNCEVFEDVTENKLVYTDIFQRYIALIESFIERRLMEKIENFSMDELTRQMQEHEDEIPLDVIDVLLSCSDFEEFKNLMLSFKQNETPNFEITGDALICASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8J8</accession>
    <name>A0A8K1C8J8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein eS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8J8"/>
    <dbReference type="OrthoDB" id="9834376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03122">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_eS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018281">
        <property type="entry name" value="Ribosomal_eS1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027500">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01191">
        <property type="entry name" value="RIBOSOMAL_S3AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="initiator methionine" description="Removed" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="29622" checksum="F802F8DA74D04E51" modified="2022-08-03" version="1">MAVGKNKRLTKGKKGGKKKVVDPFTRKDWYDLKAPAIFSERTFGKTLVNRTAGTKIASEGLKGRVFEVSLGDLNKDEEQSFRKIRLCAEEIQGTQIVTGFHGMDFTRDKLCSLIRKWQTLIEAFVDVKTTDGYLVRLFCIAFTKRRPNQIRKTTYAQSAQVRAIRKKMTQIITEEAGKCDIKDLFLKFVPEIIGKEIEKATQGIYPLQNVFIRKCKIIKKPKFDLVRLMELHEGGAEEKGAKVARQEDQLVETMAGSGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8W7</accession>
    <name>A0A8K1C8W7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8W7"/>
    <dbReference type="OrthoDB" id="62564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF193">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="301"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="716" mass="81862" checksum="8F81A9B31E1D0ABB" modified="2022-08-03" version="1">MAVFLLAQVVYFHDYFTETLKPVILAWWGPDHEELLRPTYFTVFAVFPAVFSLVLIELRRDVGENGYFSSTLRRKPALFACFSPWSIGEWLFLLVLVGGNVSIFRWVFLRRLNRIRATFTEIPLHDDDPISFDDYLSIIAVSLGSNCAFNLAFVFLPATRNSAWMTFFNISYANGVKYHRWIGIMTVFAAFAHGLGFTWIWIRKGNWKKQALPCFDCALDSFDGRRVWIHVFGELALLLFLIIGFTSVPCIRRKFYNLFYYAHQLFILAIVFSVLHWGPIVWWIFPTFLVYCYRRVISTSHAFSPVQVKELTALDNDIVKITLHRSTQTDGHFHVGQFLYINVPALSKLQWHAFTIASSPHANPTTLTLYIKSLGDWTRDLVTYANDCKQQDVLPTVYVDGYYGSSLGVYEEYSTLCLIGGGIGATPMFAILEDLVSKLSSGRGSSLRQRVVFVFSFRELSLLEELHPLLLRVKELDPHEQHFKLHFYLTRPVGDDVLSKSLDHERLQGFQQHIQPTQYSAVVTSKVPRAFYQPLRSRTSTVVVSLVVFVVAWILLVYLEYGNGKITQGGNRPELWPLQRVVEAFTLLLAGALVYIFIFAQRMSNASRSCTSLIWSTTPFMSFKEDFESYPVPAVPRTVRDLLHLHRVTMGQRPPIKEFLARVHDTHGFASFKRPSESSAVGVFVSGPSSMKRGVEEAVTALGSSRFEVHQEEFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9F2</accession>
    <name>A0A8K1C9F2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9F2"/>
    <dbReference type="OrthoDB" id="68095at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="668" mass="73888" checksum="0D9C6C6FCBD1C5F2" modified="2022-08-03" version="1">MSTRRAKAHSTGTSVHVSTKRPTIRRVHSAGAGAVSGSATGSGTSSSSSATVSSSSSVSSASSNADKSKLRANRERRRRERNLEDDELEQKFSNLSVSAPVFTPAAMRSSTLTSPTASWLAKAKPAQQRRVPPVYQKQQQQQQEEQATPVKPPTPMSQWSVPSPKEPKETKDRSASVERRPRRQRIGTLGFSRSGAASPSMNRRTPTTPTSGSFQPSLQLGTSTRDTASTESTGNLRKRSDSTGSDDEYGSDDEVYPEKAASTSGPSAFPERLTLFTQQKKVPKNVVSRGAVIDTVFAALFTKKEKSRADHRRFSAFGDDDDTGTETDEPNEDFVKRGLAASLFKDSLDGTINLDFARRGHLSDEEAIDRFITPAFIHTLVTDMRFEDFRTASARIDILRAIHKSCPTKRIHIARALADATSLRYQYVVALTTKAHALEIEKNKVVVNHKNDHSHGFTELLRYAIEHVGESLNSITGASTNAAISQRQGDELVRNYLLALVYLWRTHWWDTAGSDDEELITCAGQFVAYVPQVTPELLDRLLRYWPTRFPPQEVIAIRMIARVIMTSPPLHTLNDPRSARLPIRVFARLAQSVRSSNTQVAQEALAFTGCQFALVHFLGHYEEIYKVISEAFHTNATSHWNAGIRTTSEGHFDRALDYAPIEALSTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9N4</accession>
    <name>A0A8K1C9N4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9N4"/>
    <dbReference type="OrthoDB" id="68267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25022" checksum="162CEE0F93B66107" modified="2022-08-03" version="1">MPANSKTNTVLITGSSRGIGLALAAEYQAAGWNVIAAARNPAKAEQLQSLNVYKTIQLDVADEASILRAAEELNGEAIDLLINNAGIAYPDFFLTETKERLMQTLEVNTVGPFIISRAFLPHLKAAVAVNGSAKIAQISSSMGSITQSTGELLHPSYRASKTALNMLNNVIAHSVKDEKIATVVLCPGFVDTDINGHTGYLKPSESASMVAKNIANLTLEDTGKFVNHEGTTIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Q6</accession>
    <name>A0A8K1C9Q6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Q6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="44175" checksum="4CA9470333089859" modified="2022-08-03" version="1">MLPPGEFKKHVRAIEHGCIWMDMKTKEKVVFHIEPAAGKYYRALSDMMGLQWHTMDYLSLGNGIFLRARAFMKTYYDVGQSTDGKKYFRHDVTSDLGVDGTLYYVLMINEIVIVLINAADVGIVAMIAVRPLLRSKRTSVYSTDSTSTSTNTPVSLKKLSVQLQNRGSKSQVYVRTESVQLKQSEKNSTLSKMLLYTDLTSVSYHKPLLSMLLVVDTPLSWLWVVPNSNVFAWATIAFQVGSAYLSMFRVWIIVLILIDDLWKWTFVFVHEKLAALITEFTYVKSFEIMCATLIGIYIAYDDIMNICVLKYGLVDGQRAMTPTSPTLASFYNSYTQYSWGDRSNDHEALYYIYKHSPRSLSTAYYSAFRVAGSLAGQPRVEAPQRHSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9S5</accession>
    <name>A0A8K1C9S5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9S5"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:001087">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="40397" checksum="B82425539752A993" modified="2022-08-03" version="1">MDKASASQECCSSGSFVTKLYKMVDTEPATIVSWIRGGTAFCIVDPKMMAEHCLPKYFRHRRFSSLIRQLNFYSFYRVQEGQLTIYQHSFFRKGRPDLLVHIKRRGAGKAKDPWFDPLAPPSKPSAPVNMNSLMVSAPMDTRGPLADVSPMNTSASMLCYSPMAKPLAAPIDNMSPALKPGIAHLAPPVVDLGGNMSLDDGEKYMASQRWGSQLMDLNDTKNDLNGVITRSDFGYSDMPVMMLNAGPTKTMSSNSIDIDVQDFLTDDCTINAGLLEKNSPEDRATSQMGSGGVVSAKHAMVARDCLKWETVDGYGQDAQRDEEDAAFEEELLMDLANVEPGTWEMPLSPLNDEEEDMMPWLDLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9V6</accession>
    <name>A0A8K1C9V6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9V6"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="41740" checksum="55DC0AE6FCB46F3C" modified="2022-08-03" version="1">MNSPRPQELDTLQRIQNQVQRVQEHVDTRLPRQYQHVTALVCGWKWRLATLKQLQQLTPDGLDAIVKRVRMEVGTFDYQAKEQGELLTRFLCDLDNILSYGNVEVKEARKALVVSIQKLLERADTVKTKAAKLKEFAERTVGEMTLSSLTEEPQVDSTTEEADVVMGDVTEEEAVPVGMHALFASEDEEVVDEEQEDEDADAEEMEEEEDDDEEVDEEGEPEETAQPQPEPLPAQIDVSSLPLWKPYYQLQQRPDGVYLLAKLQGVDPRHVQVQYLAEAGALVVSGFKLPTHKDIVLSRFSGVPTFGRFRIVQRVSPDMLNVEQATQQLLNDGTLQVRLPYHYVHHPRFYRRCPPVQPRGRLMVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA67</accession>
    <name>A0A8K1CA67_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA67"/>
    <dbReference type="OrthoDB" id="187748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="16741" checksum="B771211DB54ABA7D" modified="2022-08-03" version="1">MSPPPNVSDLEQLAHGYPDFIGGEAYSTSKLFNLLFMKEFVRRYPNGPEFIAYTPGLTPATGLLRELNLDISVLLKNCKDKNIPVSTPEASGGFMARLCVEDWTVNDWTSDMYIRVHTPYEPSKQANDADLARVVWEKSEELVTRAIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB00</accession>
    <name>A0A8K1CB00_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004742</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB00"/>
    <dbReference type="OrthoDB" id="72460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="11"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="22609" checksum="9804A25230FC41E2" modified="2022-08-03" version="1">MSQATRSAPSRSTASGGVWSASEHERFLEAMRLFPQGPWRVITEFIGTRSIKQVQTHAQKYQQKLLRHQRGLRKRKNKSSRHEHRLDEITREQFINGHIVRQSAIFPVTALSPRSPSGDVDAHSSNLLKTQLPQTMTAPSLPAFHPRPTYYEEMPPHSTFTHIEPLPFRHVQPAQARDWNEPDLQVLMETLEIVMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB93</accession>
    <name>A0A8K1CB93_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB93"/>
    <dbReference type="OrthoDB" id="68108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="333"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="456"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="608"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="813"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="684"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="820"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="893" mass="99143" checksum="60F9B9DB9A364D59" modified="2022-08-03" version="1">MSTSQRVDFPVPEHLAPEVLVTLEQHEELRAFAMRMTEEVIQEGPTWARTNIKAARDRGWKVLSRTAEGCFLLKSNSTSKNTTISMGNSAPAPVRRRSSSVDSVTVSRKPVTQPTSASANGCGFMGHMRLPGLGFDDVVGNFLCDTTEKQRKQVSKDYGSAYLDTAVMTTLEGPKPHDPFWYLGLKWIAMRSPFEKLVNHREFVFLEHSGTYFDPTGRRMLYRIGHSVNLSDFGGKNNYFGLTRGHLELAQIFWMEPVEAAVSKSGAEILQVCSKGLADVKGKVPTWLVERYLRRFWKAGNTISQPENDGVVCPQPPPEDQLTLHLATHWVPDSERSACYVCQKRFHFGRRRRHHCRACGEVVCRACTQYYQLAMGNGAGGLPFDFTDNSASARSWHGFERDDENEMATLGDAPRPSSFRKGRKTIGSLDMTGATRGKVCLRCVELKKVELSRQLKARRKGLSSRQSSSKNPLSLGNARQSQYPIHEEDEDDQLRGPQDELPMLVAESDTDLEQDDESDREYSVDDDDDDVNSSRFKPFSTIKLSAGSDSGKGRRKAYSQYSQVDEEYDSDGIVFGGSTRGHRRPPQSFDPTRTIEMPFGQANFNARHSAPQLYDSLLENQSEDRMTLGDLLDDDEVSTRGDRANSSQPAFKSQGQPMVPLRRGSSAPPVAHKHLGRPSFLASDDGESDREYGVDDSDDDNQTSMTQSFASFASFDADVLIDSDAVDSHELGSTRVIEDMRKNDPDNALFARIQNIQDEVLRQQLLSSSSASVASVAPSQSMATKPFSATRFQFFKPTMPTLMASRRMAFGQAPTMPATSSLIQSESPPQSESSTVDSSAMSNSSSSVASDEQGRQRLQSGVEESIADQAYLLMCIQKERARAQQLSSPYGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBR3</accession>
    <name>A0A8K1CBR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_000120</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBR3"/>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="14">
        <location>
            <begin position="116"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="14">
        <location>
            <begin position="307"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW60078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="471" mass="53858" checksum="7CB7F3F4D8EAA586" modified="2022-08-03" version="1">MLSEDVARQVVGYVHDVLHSEKADEIMAQIHEVFRRVGFPKPYPDAERLAIAVATGLFTLIAYFVLFGKRHRRRRKALQEDLNKAYEKVQELQEKLAEMEEEEDGGKPKNQIRIWMDGAFDMMHYGHMNAFRQAKSLGTYLVVGVNDDESITACKGAPPVMNNEERIASVVGCKFVNEVEPHCPYIMNEEYLKRMIKKHNIDYVVHGDDPCIVDGKDVYETAQKLGKYRTIPRTEGVSTSDILGRMLVMHKTHHTYEGYGNGQLSSKVASNDKAAYERPSKFLTTNRMLRLFSAGNREPKKADKIVYVDGAFDMFHSGHVEFLKLAKAQGTYLVVGVHNDSIVNAHRGLNYPIMNLHERVLSVLGCKYVDDVLIDAPWHITKEMIASLNVSVVVHGTHRDRDHLKDFSLDEHYKAAKEAGIFKLITSPSKLDVNDIVARINDNRERFEKKFVSKMKAEEEYYADRYDTTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBT1</accession>
    <name>A0A8K1CBT1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-mRNA polyadenylation factor Fip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBT1"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044976">
        <property type="entry name" value="FIPS5/FIPS3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36884">
        <property type="entry name" value="FIP1[III]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36884:SF4">
        <property type="entry name" value="FIP1[III]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="154"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="484" mass="50902" checksum="40A6CDFEC938CEF4" modified="2022-08-03" version="1">MEDEDFGEDVLITTKSERSAREAWAADAGKTEAPTDTAAKSAVVDEDEDLYGGVTINLNKAASAEARGATVKTEAGDDDEDDEDEEEVAILLTNDSKGAKPALRFTGSNRYVRSSFPGTSQHVPIGGTNMQKLEGEQDDIDDLAVFGGRRTAFDVDIDMLEDKPWRKPGVDISDYFNYGFDEHSWREYAAKQLHTRRQLAMEKTREQAARQAVSAANAAAAQDGKAPSGGSAQEGEQQGGPPGGQWGPMAGGMPPQGGPPGFMPPPRGWHPGMGPPPHGGRGFMPPPGWNGGGMPGHPPPGYWEGGGRGPPGGWMGPGGEERGGRGGRAVVMTEVAEANATHQNPMLLVIARAHDHVLLLLDVTETLVDGMHQKTATPRVVTVVHVIVIVTVTEAAIENASATETETESVLAKLVTETVIVRAPTATVTETRAVIANANVVALDPGTVTHGSVRVVTRAPLVVAATRVAVVDPVTHAPSGDIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD10</accession>
    <name>A0A8K1CD10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013612</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD10"/>
    <dbReference type="OrthoDB" id="14603at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="108" mass="12329" checksum="4DA097081BB06952" modified="2022-08-03" version="1">MSADDVLSNPPCFRTGLMWGIGTGLVVGAQRYRMTKQVRSACDFAVLGFGVVAAGSWVFCRNAYLSRARYTRQFMEVMNDPNRRMEAQEFFRSRIETKESEEDKKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDF8</accession>
    <name>A0A8K1CDF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDF8"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="141"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="41096" checksum="997B7EB288ED2A29" modified="2022-08-03" version="1">MSSTTTSVGWDTTLAGQSWASPMPDSASTMDTSNLIERTREVAVSDANDYSRFKNIGDSDSDDENAKSKSNTAAVKPSESGVEACRNCHKPGAKLKCSICKKAAYCARKCQASDWQFHKRICKKPEEKKPEPPRKQPSPSKPEASSSSSSSSASSSSAAKKTTTPGPKKTTTKSSSTEVVVDEPDLPASEMRGYKNGLPYFHRELSEHEQNLIGDIAPKKVEVAPEVVQPTAHAGSAWNAAGTFEERNFTKWAEDKWRAVFTNKTYTEGSYNATLKSPDKITGDASVCVVRGKKRFLFDFNFKLPFEIVVSGTTYRGDYQMNDISNDEDYEISATWSKKPSSAAEASALHKFVSGGLKKEVVRLVGDFIREFQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDN1</accession>
    <name>A0A8K1CDN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDN1"/>
    <dbReference type="OrthoDB" id="164487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50607" checksum="9B5D342C3B170DDC" modified="2022-08-03" version="1">MARSPLSEAIPDLELSPSEQHDVIEKTAAVLAETLDIERQFLVGRGSLRKSEWKQVRGGRGDFRLFRERRRSQSQRRVNTADMELEKVDTGLEALGLEEVDWPDTSSVNESLYSDSISGSFVSDSVPLRFLNQLPDDTVMSNTSSSHSSGGASVTPTSDYARIPMVVSAGQVDGNLEDVLFGWFGGDDRSWQLRSAYIKDKYTDARILSTVLAPTPEDPYRFLGVKWFARQDSSLVFGTLIKDRDFLVIEATGLTRDENGVPHGYYIMHSYRHPLVPEFSDRKILRCELSLCYISRQVGPNKVHIFNRGFIDPKGIMPPSIAITISANALSGCAKSVETSLSKKLMWLVEQHKHDREQLESQRNEAMSSRTCEVCNKTVRFLTGNLSFCHVCGLCACSNCTVQRRLVVDISASGVLDRVLSFCSTCVLTAKQLPPHQVAADTLSLTPQFLDLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE64</accession>
    <name>A0A8K1CE64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013608</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE64"/>
    <dbReference type="OrthoDB" id="2187at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="359"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="638"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="912" mass="98260" checksum="95575FE3A8F66A46" modified="2022-08-03" version="1">MTMWCSSFAVDDAVNSAIQKTGDSAFDAHDASVSVCGVVWSDDAALTRTKGGKEDVMTTVYTTEIALLRQLRVISGSYVVVSFREKHHVARLVLTSRSEAKSTRETGKTDADRPTIVLTPLLAFNLGVPLHAASGEASASVHLTVRSAQPHEIGLSSALTAPFRRLSEQKPAIASKAVIAPLLVSSLACREHAVMQTPDGLLQAMRSHFTTPQVLQTGDVLAVTLEETYPSTSEADQSVKTSFQTVVIPASLTTGEEGDVTVVLPPALPVDTSLVFFRVESLEADASTPEAPLALSVSSDTELLQTGSVSAAAPDEDAIKSYLSGVKYEDECASSSTMLQSAALDRLYEMLHPSQLCDVPVSVLLSGPRGVGKTTLLHQVAKLLGISVVEVPFTELTAQSELHLLENMREQVAKAQALAPCVLYISHFFAVEKNDEESELRVAAVLTECLKTLSSSSVGGSHNIPLVACVDDISEVPKFIRQCFLYDLAVEAPDQKERHAFLKQLASTTQFDKEVELQELAQRTAGRTCGELCALVTDAGVRAIDRLRRDSSVSLLDRLQQGLLDASSDSCRIAWEDLEGAIKHQQSQSSAAKMGGAASIPNVKWDDVGGLEDVKDEILDVVQLPIMHPELFASGVRQRSGILLYGPPGTGKTLLAKAIATECNMNFMSVKGPELLNMYIGESEKNVRQVFARARSCRPCVLFFDELDSLAPMRGRGSDSGGVMDRVVSQLLTEIDGLSSGGSASGDQVFVIGATNRPDLIESGLLRPGRFDRLLYLGICTEKAAQLKVVQALTRKFTLADDVDLEAVVEHCPTSFTGADFYALCSGALAAALKDRVEQFDQQLEELNAADCYSSSPMTARVLLNRLSPEELAVRVAQEHFLTSLSQVVPSVSPAELLHYEKLRDQYSSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE99</accession>
    <name>A0A8K1CE99_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE99"/>
    <dbReference type="OrthoDB" id="167324at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="36405" checksum="0DCFDBFD94B6FE6A" modified="2022-08-03" version="1">MPQLLRYLTIFAGIQGRGYEHFTLLRDIIQIICQSIQAYDASRFTSNASVILILAHRRMTMLLTDLLVDFVCLLLPTLLWKHYLNAYFSGEAFMYRDTSNARAVMELRIVFVASYFSLIVKVIPPMSVFLTVGKLRQLLRRPHQVKDTKGVLPDTTRPSLEPSSPSIRNIPNHRVRLRRAARFVSWLLVAWGITVIIIDRCAVRFSANCEMGCQLVVHPWFGSSDCSCTVQEINCYTRRIGGRNDELREIFSGLDHSGLASLIIMHCDTLEIPDEIHWFPNLFTLEIYNSSIVSWPESAEISADAFVAWDRCILYEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CET4</accession>
    <name>A0A8K1CET4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013701</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CET4"/>
    <dbReference type="OrthoDB" id="206848at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056304">
        <property type="entry name" value="Lip-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24708">
        <property type="entry name" value="Lip_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035468181" description="Lipase-like C-terminal domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase-like C-terminal" evidence="7">
        <location>
            <begin position="27"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="51073" checksum="A4087E5455158CDE" modified="2022-08-03" version="1">MTKLFTSFVAALALVFVVGSSLVSAANKYPIVLVHGCGGWGPGDFFNIPYWGSLQGDFISKLKAEGHEVYAVGVGKFSSDWDRAVEVYTQLKGGRVDYGANHSATYGHARYGRTYPGMFPKWGEVVDGQIQKVHLIGHSQGGTTIRMLAQLLNTGTKGAPVEEDPNGHPLWAGGKDWVHSITGLSAPFQGSTLTEYMSKAIDGIETFVATLAAIYGIVGDLNATFYDPVMDQWGIAKKQPNESFIDYFKRLPTSKLYEPGFWDNAASSLSIAGAKEQNGWVKTLPQVYHYTYVSESTFNFRDFKLRKIALPNPTVTNPVMLPLATMLGSRDTVKRGFSEDWLPNDGFVPKISQLGDGVAPVVKFDGKSVRGQWVRFDTMTMDHWGAIGANPFQKVYSMYSAHAKLLADLPSHEKPNGRMLSDDSNAGNVTESDVDVHEAPSDIIQAIIDAQKELLPPADLPPEVQDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFH9</accession>
    <name>A0A8K1CFH9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFH9"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="511"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="66149" checksum="AAB53D1AC2337EA9" modified="2022-08-03" version="1">MATLAARVVSTRLRAAALHRITRNRFLMASSLSWPRSVSSSSSSTLVGPHFFDRVLGHAGNVALFEESTSTTGDALASWSYAQLLHEAIRLRDVIQGILPSLARADANPPRIAFLGSRGASYVVMQWATWLAGGIAVPLHSSHPLEELQYIVEDSGASVVLVSDEFLANPTLSAFAEQLKTTKSGSLSVHVHARPVPSSQSARLSDQETSVVRNWVESCQFDKVGAHIVYTSGTTGRPKGVVTTHAGLTAQIHDVVSAWEMSADDHLLHFLPLHHVHGILNNLLCVHYAGGSVEFLSSAKSPLIWSKLAESSVASVKTRPVSMLMAVPTIYMNLLEDMERVQQAKDATPPYDVKAAITEAKRLRVAISGSMACPVSILNRWEALTTHRLLERYGMTELGMALTNPLHGERHLGFVGGPFPSVHVRLVDTDTESEIDKTTEHEGELRVKGPSVFREYWGKPEATAKEFDADGWFKTGDIAQYSNEKESFRIRGRASADIIKTGGYKVSALDVERVLLTHPEIQECAVFGLPDEKWGQVVAAVVRATRSKAEDFTPPLVGFTKTHLADYRVPRKYFFVDEIPKNAMGKVNKKALAMLFAQKAKEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFZ2</accession>
    <name>A0A8K1CFZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFZ2"/>
    <dbReference type="OrthoDB" id="67358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="785" mass="89582" checksum="3CE9D034F6975413" modified="2022-08-03" version="1">MIDTRSRFTAPPLPRFPDIPIIPRAHGDTSDDSDEELELFASKEFFTIQEDLFLVRHHCFQPETVLPELVTKFRREFGDSKSSDDLMMRLHLLQSDAFRALFVLYLKAVSLNRGINTMPSTAAPATVRPEVLVLLQSSRTTCETRLLQLIYDDEKLQQAEVAEMVNIEVTSRNFPKYSRPAHKRQLQRCSKVIQDLYRNVEPGLGGTTTPHQAFTLHAANTATEKLHFTDSVSFYDSVMVFNHLEQPVLDRLLLFAKDPHVMERYTLQKQQQQESTHIKRELRYQLQQIFEAQRQIHEVKLEEQRRSEYERVKEHLEQTLEEDILHLRRMHEMLLQAERAKINAKYDAQIALVTTQIQQMRTEIATLQRECDNNGWNTLDREIMQSSVQIERIFGSSDYILRLLILAEDLDAEPLRRALIRYLSRDRIFPQFALRREFTSKMISETTVLAIVKGISTSDLREIDGSGKSFVYHELTARELHTRKIAFGRFLASLTNDQLRAVSRFREAKNPSMTEDFFSAEMLAQITAVHDFPELLDREFARRREFTTVKMNSLTVDREVSFSEDDCVLQLEASHRYCAVFATKERKHGECGKWMFEVTIEVFAGEGESMLVGWEVPRSHITSPSGDSLSSMAKLPAFVPGLSPGSDGRSFGITWQSDGGLEMGMLHANGQSKSGVPCFRAGDVLACTINQDELVPLFRFYLNGVQVLPPMAPATSTFTPPASVIPGASSSAGSDGIACQNAVYCLFPVLSMYSSRKKPQMRTRFNFRGNFQYPLPGFEPYGAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG95</accession>
    <name>A0A8K1CG95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 418</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in photoreceptor outer segment disk morphogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Photoreceptor inner segment</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG95"/>
    <dbReference type="OrthoDB" id="47374at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029239">
        <property type="entry name" value="CFAP418"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33958:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33958">
        <property type="entry name" value="PROTEIN C8ORF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14996">
        <property type="entry name" value="RMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="48"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="377"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="535" mass="59543" checksum="8B1EE4AEF051D15C" modified="2022-08-03" version="1">MEATEMPPQSTPHGVASASPALGALSESLSIASKPLPSSAASTTQAVTVLRGMETDDIDQVRDLHEEWFPIRYQQSFYDGAAQGIWRETGHPLFARLAVEVTMSPATLKPTSPTYDYQDWYPAPSTAQGTILGAVMASTIPLTTVEDPDLIDDDDYIHTHAMYILTLGSRSSVRRRGIASALLAECIEEARRQPHCGAVYLHVKADNVQALRFYEKNGFQNLRYLHDYYTINGVRHSAYLYILYVNGAMGPTNWLEVITKPLVSFFSMATSGLKRWIEAFLDDEEEHKEREKKSSHRPSAPETTVSIAYWLQEQREISISLMDLQDLLDEVEGVLQDRPSDRKAVVSRHDARINNSTVTSSGTAVKKSTSDIDDLLNMIDDDDEKPDARHAVHPHRGVTSTFNTKTSTSSTSSYASSSSPPQEFHTGGTKKCSTLMLGGGDVKRGLNTAFASHNVCLNLRCNECDFTVVQFLGKKWASNADYMFFRENVPNESKLRARMEIDPESAAYACQCKWLSIDVCTRIDMCRVKWSCAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH59</accession>
    <name>A0A8K1CH59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ammonium transporter AmtB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH59"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF60">
        <property type="entry name" value="RH50, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00342">
        <property type="entry name" value="RHESUSRHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="7">
        <location>
            <begin position="45"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="457" mass="49567" checksum="6BE86648160FA9DB" modified="2022-08-03" version="1">MFKLSQDQGFMASAAIYEIVCLMFYAVHFETAHYKNTKSSGDEPTRLKEVYAMFMDVHVMIFVGFGFLMTYLRKYSLSAVSLNFVVAALSLQWGIVCVTMAHQIGDDEYPKKIIDVPTLINADFAAGAVLISFGAVLGKVTPTQLLWMSFFEVIFYAINEYILVELLEVIDAGGSMVIHTFGAFFGLALTLQIGAPGASEQEHNRSRYTSDIVAMIGTLFLWMYWPSFNAALVPSDGFRQERAVVNTLLSIAASCAATFAASKIFAPYKKFDMVHLQNATLAGGVAMGATCELAINPASAVTIGIVSGVVSVIGYVFFTPALEERIGLSDTAGILNLHGMPGVIGGLACGFATMALSDDFYDATLTEIYRARGHRSAGEQGGYQILATVVAVGIGIVSGSLVGRLLRSPLFRQQQMLYEDDEWFHVPLEFPLTTTSPLDLSPKHGDIAGNYTAIQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH83</accession>
    <name>A0A8K1CH83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PAAF1/RPN14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH83"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF19">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT RPN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="445" mass="48042" checksum="EA7F2C2B35E8BF78" modified="2022-08-03" version="1">MTAMYMDLQPDWEAAGDETCWLNVYERRVVLNASESQQEKPTATVEGAVNAHFQLAMQPAATGKAETAHLVEVTKREMHWVQVQVASGSTGEEEVVHAVFQAPTAASDVFQAAATEQVHEFSVHRSPRPQLHCVDVSCEEKYAVVGGADGRCVVWDPLDRVPVRPLVGHVLDVTSARFFPSGKVALTGSLDFTLRIWSVESGQCAAVLKGHRGGIEDVAIVGRGRNVLSCASDGAIHLWCCANQQIVAKWTSDNESAVHCMSLLDDSAHMFTAESLKASTAVDNEFETEAKLLFAGLDSGDILGVDVRSRELAMNLEGTASIVSCAVTSRHGTPTLLTGSEDGLLTTWDLRQTSSPLHVLSRSPSAVQRIAVYEDRVWTANADGVSASWSHLLAPTNATPTVSSYLTGPQYDPVRGLAVGPQTGRVFTACRDGLLREYIPHFLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHL6</accession>
    <name>A0A8K1CHL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat CIA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHL6"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000136">
        <property type="entry name" value="Probable cytosolic iron-sulfur protein assembly protein CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03037">
        <property type="entry name" value="ciao1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028608">
        <property type="entry name" value="CIAO1/Cia1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="193"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="238"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="335" mass="37544" checksum="26818FD594996C8B" modified="2022-08-03" version="1">MALKEVCVLDGHRERAWHVSWRADGQMLASCSGDKTIRLWAPPNQGARDAGKWECVAILEDAQGRTIRACEWSPNGRYIASVSFDATTVIWEKQGESYEVISSLEGHESEVKSVAWSPSGAYIATCSRDKSVWIWEADPDTDFECISVLHGHSQDVKFVKWHPTEDLLFSASYDDTVRVWAENEDDWYCKETLSGHSSTVWGLAMDPQGLRFASLSDDKNVVVWERNTASGDVHADGSRMEWKQVATLSGYHERTIFSADWSCQGNFLVTGAGDDAIRVFQDAAGAFELVHNQPKAHTSDINCVRWCPRLEQDQKSLLLASAGDDTFIRVWSFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHW3</accession>
    <name>A0A8K1CHW3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Maleylacetoacetate isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_002214</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-maleylacetoacetate = 4-fumarylacetoacetate</text>
            <dbReference type="Rhea" id="RHEA:14817"/>
            <dbReference type="ChEBI" id="CHEBI:17105"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="EC" id="5.2.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHW3"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000010">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000041">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="GST N-terminal" evidence="12">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="13">
        <location>
            <begin position="94"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW63273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24716" checksum="921578FCAD4247E6" modified="2022-08-03" version="1">MATSGETPVLYSYWRSSCSWRVRIGLAWKGIEYANKPVHLLTDGGEHLKEEFTKMNPNQRLPALIIDGHTLTQSAAILEYLEETHPEKPLLPTDPLQRAQVRTICQIIGADIQPIQNLAVMNKVVEDLPAEEKAAQKVAWGKFWIQRGFVGLEQELARTAGKFCVGDTITMADLFLEPQVYNANRFGVDMSQFPVISRISAELSQLAEFQAAHPSNQPDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHY7</accession>
    <name>A0A8K1CHY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002057</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHY7"/>
    <dbReference type="OrthoDB" id="264785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049270">
        <property type="entry name" value="CFAP58_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF0">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21771">
        <property type="entry name" value="CFAP58_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 58 central coiled coil" evidence="4">
        <location>
            <begin position="392"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="851"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="123"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="923" mass="107972" checksum="FCD782301994FDCB" modified="2022-08-03" version="1">MSKVSSLDTPPDTPSGGEGKQLHDDVSLEATSLEALENDFQEVLSELAGDKSLERFRLEYEKLHRALKKSNAQEKKLIKKCRELNAEIINNAAKVQTALKLSQEDQASIASLKKEMEKAWKMVDASHEKEIRAKETIQQLKEEINNLSRLVEQGAGLSVGQENMLKEVMRAKEELARANEEHEANAKKDHERLQELHRRIHEMEQSATQQKTEMQNLKDQLAMKAAEQEREARRKERLDKELRDMRGKLEKKTLEHATLTTDFTKTQTQAQSLEKQLSEARSTMDKYVRDYETLFGRTQKLTDLLNEQNDKTMQLEVERRNLENELKMKQDEVHRIRLEKTMAERKIDKEKRSTQKLEEKLEDEHTSKIVLQTQIKSLQRDLDNDKVNEDHLRTEMEALEREKQMHLKNVQKAEGKAKKAQDEVKTNERVAKNLEQELAAFKLEASKQRKLIYQLEKEREKYGMEASEQRKLYLQAEEEAKLKEMRIHEMQKKLNEGETKLKQQQQLYEAVRSERNLYGKNLIESQDEIAEMKRKFKIMTHQIEQLKEEVSAKDIALVKEHFDHQKVEKQKEQHKNELARLRALLATNEETINNQDAEIRKLTTMIRRMDDEALEQRKEYDQVINERDILGTQLIRRNDELALLYEKLKIQQSTLSKGEAQYQERLQDIRVLKLKITDLKRELYIAKHQVGQSDELKREVYHLQRELLQEKTKVKALSEELENPMNVHRWRKLEGSDPATYELLQKIQTLQKRLIQKTEEVVEKDLIIQEKEKLYGELKTILARQPGPEVAEQLSWYQQVVREKDKQLKSLLSEQNMFQSKENGLKFEIERVARELHEFKRKYYKKKLEDKMREKNAPVVAPPPLRSNQLPSQSTSGSGGGDRLPNLTGSTAKLARPSPAEAQKQLAVAASNRFVGGGFSLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK78</accession>
    <name>A0A8K1CK78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012863</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK78"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03467">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054716">
        <property type="entry name" value="Sol_Rieske_ferrdox_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496">
        <property type="entry name" value="FERREDOXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21496:SF0">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22543">
        <property type="entry name" value="Rieske_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="18"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="19838" checksum="AC360FDD0873A9E9" modified="2022-08-03" version="1">MDSRQEAAAALDALLSYEYVCKLEDVPDGTRRCFLLPSSQRSILLINLKGQVFCIDQTCYHHGGPLANGDIEELAGKITIKCPWHAYHIAIETGEGLYMGVDMAFGPGGKLERTSPRVKTKGVKQRTHFVQIRNGDEVFVADSSQIPGASPIESDIYAFKKTTIPGRSPKGSVRIHSRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL77</accession>
    <name>A0A8K1CL77_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL77"/>
    <dbReference type="OrthoDB" id="167142at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="723" mass="81056" checksum="9B593B2A0359F942" modified="2022-08-03" version="1">MPRVLQGLRARYEALQAWVHSTQYLGRYSIEKLHLFEHYQRTASSLRVVAVICLAPLPTFLALLAMDIVPMNDPHEGASHNAVAFIRSTLSHGLMTAMTLLPLKQALSLTDDEYAYKTIAVIAVLTSLTIEAVCIPLAFLWRFPLPFREMIGLPIWATSVATYNYLFAKKTLFRHWRRFKRYLPIVGVQLVVLYLWLGCSIGFAYLSLLPQILVIIAFPLLKVSLKSALWKYARRLDDISTDVTICLLEISGALFQTVCMQYVTSKALNALVMVTDLVQAVHEVRAHMKMDYLGDGKRTLLTARKIIESSVFPGHSVGDGEAPLRRKKTQSSDTNRDDGMASEVGQLSIRRRSSRLLLRSSDDSTSPLSTRHRDNGGASAASTPRGFGEKPRRQMRMQANSVYIPAQTVYRKSKRRLLDLDKVRADDLSGGRDSDPGAAEQSAVNIPIEALTSPPASGPRRRSSLPTTIQRGGSLVRIRLTASIKNPRIRLFCSSSVSKHTPPAFTEIEKPPEHSRHLARVHPVTAADIPSTQSPPLRLRAVQYAANQLEEPKPRRPSIQKAAELLRRRSKRGSAVIIDGIIVARPEQARILEQTLQLLFACEVLLFAEYMEVVIPFLYALCLGCDWVLPNGQYNLIVRDMSDSDIHLMLISSFMYALLELASLLVMYYVMKTKYGVSAFCQLAFVLERYWLTLQGKLVGAFIVIWNAATIHQGTDFSFEFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNF2</accession>
    <name>A0A8K1CNF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase mitochondrial F1 complex assembly factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014084</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNF2"/>
    <dbReference type="OrthoDB" id="16535at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27348" checksum="E057C0BA3196B9C4" modified="2022-08-03" version="1">MFITRRFLTELLVNRINRPSRVLIRASMSPLAASLRRALAPRALLRSRWLSTEGKGPSGGGFSFPAPQTLQQIVKLDLLVNEEPTQIRRIWEDYHSEKDDAIARVLDGTEYSTLMERARSAPYFIFPVYRQGGFFNMLCQFQDKCFLVTYLEAFKENPALAPPCVTVSLFDDLLAEKDVGLLRADVVNMLDKAETEKLLNQLLRSYSNEKLYDWVDKFNNRPNEFDFDAFRHAIDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNI2</accession>
    <name>A0A8K1CNI2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNI2"/>
    <dbReference type="OrthoDB" id="94166at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="36317" checksum="8480F5BC7370563C" modified="2022-08-03" version="1">MTVYKDMYHAKSDPVPVYPGTPSTVGSDESNRGLRLLGVGSIVGNLEDFMLGNATISAEQMRIRTSYTDDECVDHRVLDVWRQPTVEDPFTLHSLRWYVKAVPGANAIVKPRDLLLIDCQGILETTKGDRLGYLLLHTVEVPECREIPGIIRCQLSACYIFRPNGPNSVEVYLRSMVEPGGKIIDSVATISSTNALISTWKLPWVGQNRKLTWMMTQPTSVRAEKLGKKVAATKPARKDKCSLCTKSITLLRRVSACELCLDSVCSRCLTVRKLSYIRRNGDLVQVPTAFCKNCIMWSTRLDASEVARAMFVFGCPVGYSQPIYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNX6</accession>
    <name>A0A8K1CNX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNX6"/>
    <dbReference type="OrthoDB" id="197155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF7">
        <property type="entry name" value="PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="38"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="71"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="273" mass="30704" checksum="92D72D39750F06D6" modified="2022-08-03" version="1">MKINLRCFSTSDLATATDKRVAELKERLKDSPPAAHNFSFSGSGFLIAYHLGVAHALKELGYIQEDSRLAGASGGSIAALAVASNADLHQILDDTKLMAHFGRTVGTWGKLEPGLRKLFYDRFANVDLEHLAKRLAITTHQVWPIRQIIHSVHFESPDDLCDNLIASCYVPFYLSSQAVVKLRGQYHVDGGLLKLVPEIPDHVRVCVFHANMLRRTDYEISPSLDSEFPHPFFHLVRIALFPPEAHVLDDLFHYGRRGAVLWAEKQLEQEKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ63</accession>
    <name>A0A8K1CQ63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004118</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ63"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="264"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="450"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="633"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="688" mass="76616" checksum="CDF6D3120734E48B" modified="2022-08-03" version="1">MASFFGALARGVKFDAQRIQSEKQHFKKQDDASGLKTNKQANASELDFFGFDVAPAKSKTKEPVKRERKISEDMIPGWAGNEPKVAKKGGSKPRRKRKLSEGAIEEEKLAEEERRQASMLLTPKPDKDGKRKRRKKKSKKRSESIGSEQSVGDAEEAEEDQEAEEDNDSDDESINVFKNSTKQADGTSSKARKKASKAEQEKEEIRVFRKQMNIRVDGASVPPPIATFDAMKLVGTQEKMRSVLLKNIEASEYKEPTPIQMQAIPSMLLGRDVLATAPTGSGKTAAFAIPLLANLGVPKQEGIRAVVLSPTRELAVQISTEFHRLSAGRKFHIVLLSKATAATMISSIKSNCTVNHDILIATPLRLVHLIQEAKLDLSMVEMVCLDEADRLFDMGFVEQIDEILAACTHPKIQRAMFSATMMQGVEEMAQSVLRDPIKISIGVKNAGASSIEQKLVFVGKEEGKLVAMKQLIHSGLKIPALLFVQNKERANELYHELLYDGINVGAVHADRTKEQRDETMRQFRTGQVWVLICTDLMSRGIDFKAVNMVINYDFPQDAVSYIHRIGRTGRGGRQGYAVTFFTEDDMLYLRTIANVMKLSGCEVPDWMLTLKKASANKRKELVKAPLQRKRISTVSGYDLQKSHKRHLAKSKKHSPSDEGGNAETDKSKIESKPAGNKTLSKKHKTARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQN3</accession>
    <name>A0A8K1CQN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQN3"/>
    <dbReference type="OrthoDB" id="165983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="68793" checksum="BD936096C3380247" modified="2022-08-03" version="1">MGAQLEEIEWTATLTWSGPMGAQLEGIEWTATLTWSGPMGAQLEGIEWTATLTWSGPMGAQLEGIEWTATLTWSGPRTQGQRLCRGKTAFPSMRTQNHQFHEFAPPTSAGCVFHNCKNHKSAGAMHNALVRSIREGQDTGTYLVLDFDAVSHWRGITPSPFGCVPKADADPSLEARVIHDLSFPRGASTNDASVQSDLPPLTYEHVRAIARRILCLKARDPRVEVLMMRGDVKSAFRHLFGHPSVIRRFAGVLQELRVLVLDLALPFGWTGSPAHYGAFGSAISFLVRRESPATLCPGDADDESFFCYEWVDDHVLVEQAKGDRLALCDIALRLAMVAVLGPRAINEKKFTSWSTQSRALGLDWDTTACTVSMPSDKVEKALGRVRALLAESTATQSSLSQLLGSLRHVSSCFRPAKPFFQRLATLHRQAYRFVTVEISTAARLDLLWFEHILQFGKLQGVPLRFFADLPDPDVHIFMDASDQGLCALDPARREFLRIEFDEEEQVLIRDNLLSINVREQLSAAFSVLVWGQRWRPATTNELTHGEYMDASDQGLCALDPAQRKFLRIEFDEEEQVLIRDNLLSINVREQLSAAFSTTGLLSRGATRWQAETLELKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQV3</accession>
    <name>A0A8K1CQV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQV3"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="100"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="508" mass="55644" checksum="E2EFFC7AD22A5623" modified="2022-08-03" version="1">MPSLTKRKVLIVAGVVTLFAVIGAIVGIVVWQTKDKSDGASTKSGGATDASASTSDKGSSVTKSGTSGSSNSSSDGSSKESSVTSDPTKEKFTLSAYAVGDWGTTTTRDSCCKRRADHTPTNVDKNAEDVVAAIMGKAADVADPKPKVVLGHGDNFYWVGIIDDKDQAYRFEETFENKFNSKSLLDIPWVNVMGNHDYGGASYICAAGGTWAECKDEAALEAGLKAKFSLQAEYKSPNSNRWIMSDHFYVHSIEDEDSGVSIDIFNLDTNDADVHGAQQICCQCYSYADGDDKSCNSVARGDKYCFGGNTGMFDKCMKMLNDWGEDSRKQLVEKAKASKATWKIVNTHYSPYNHYAAGNIQKWWDTLDGLGIQLWINGHTHGEKHDYSNIKMHFIENGAGGGILNEAASGIPPYVEDKIEKIWNYGTHDYGFFELSASKEWLRARFLTNDDKWSVQDDFTQSTIGGVAAKHCWYIPVDGGKGQSCDTTTTTTEKHHKVHIRINSHHQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR59</accession>
    <name>A0A8K1CR59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-galactose transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR59"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39164" checksum="328D2BBFDCE8E46D" modified="2022-08-03" version="1">MTAPPSSSLKYLSLCVLCLQNSLLAILMRLSRVGDFPKFNASTAVFMCEVLKFVVSVALILYMPSSHEAQDKKNKRSLRRTFETIFDQYEMLRVSVPALLYIIQNNLQYISASNLDAATFQVLYQLKILTTAMFSVVMLRKAILPLQWGAIVLLMIGVALVQLDDSNGNAKPAAGGVPRPGHGEQNMTIGLLAVIAACVCSGFAGVYFEKILKNSGSKATLWERNVQMGFISLVLGAIGLWINDSEFIATHGFFYGYRSITWAAISMNAFGGLLTAVVVKYADNILKAFATSIAIILSVIMSIFLFDKIPTLQFIIGAFIVNTSVYIYGTAPAWAASNPKSVSVPAGILPQAIAMKKFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRL7</accession>
    <name>A0A8K1CRL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRL7"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58781" checksum="1EEF43456AFC512B" modified="2022-08-03" version="1">MADWVSPLASTLSSSTSTSLVYAAALAAVAYVSLPSPQHRAVANLPRPKSTLPVVGNTIDAMFTKRKKLHDWIYEECLRHQGKPFVIQIPGKPPMVVVSTVEAVEDILKTQFDSFGKGADFAAALEDVFGTGILASDGAKWHNQRKTASALFSMSMMRDIMDDVMVEHTERLCEIVGRSAQPGSEPLDIKHTLELYATDVFTKIGFGVDLHFLTSDNHEFFERFGRANHNLLYRNEQPTWLWQLKQALRLGVEKQQLEDVAWLDRFVYKIINDSIARRNQGAAHTKHKDLVALCLDNPTMASDEHGYDLKEIRDMAISFISAGRDTTAYTMAWVMVMLARYPSVQERIRQEIRDRLPELARKEIPAPRKDQVATLTYLEAVIKETLRLNAIIPLNTRATIEDVTLQDGTFLRAGTMILIPAYAMGRLPWIWGNDATEFKPERWIDPATNELVKVSPFKFIPFSAGPRICLGRQFSMMEMKIAISTLVSRFSFETTKDATEFAYDSSLVLGIDGPVLVRPTPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC1</accession>
    <name>A0A8K1CSC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Restriction endonuclease type IV Mrr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC1"/>
    <dbReference type="OrthoDB" id="20734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction endonuclease type IV Mrr" evidence="3">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="157" mass="17632" checksum="396FB6D41A069DE5" modified="2022-08-03" version="1">MTSRTKGLEFEARVVRMMQTLHCHLTPTQVSMDGGIDHVGHWKLPDTDVEVVTQCKNEQKPVGVQHLREFHGVLALHAPTAIGLFFSASGYSIYAQRFFTRTTHPAILCTLDEHDRFTAFYLNDRARAALPKLSVGSSFVHQQHELILTYGELVLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSI9</accession>
    <name>A0A8K1CSI9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011142</name>
        <name evidence="4" type="ORF">Poli38472_011143</name>
        <name evidence="5" type="ORF">Poli38472_011144</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSI9"/>
    <dbReference type="OrthoDB" id="167011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036433887" evidence="2">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29027" checksum="8311D9C66F6CA0D0" modified="2022-08-03" version="1">MKTCVFLAIAATLAVAVSAASVNIRGAQRDEAPASTDIRIRTTDVLNRPTGLLNKNTVAMDNNVNIARSNVLFSQNDRLAMAKQVEQALNAEEQDGTAVTLTRSVMRSVSAPDTDSSLMTKASAVVAAKGGDASTLSQRIADFVNAVDDKKEQSIQSETPRGMQLSVGTKDILRQPTAVINKNVGMSDNQITMSRTTFAPSRNDRVTMSNNAKVANAVVPGSAIRVDQITAREGQDQDDASSEEMRVPDDKKEQFGWGWGFPGYGWGGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSK9</accession>
    <name>A0A8K1CSK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSK9"/>
    <dbReference type="OrthoDB" id="5985090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="152"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="36899" checksum="CEF2B2008C667A9F" modified="2022-08-03" version="1">MSDNGDGDARLELFKEFVEKYDIDLEDPVDTVQEFEEVEELDLSEKDLTKLPSDLGQVLPPNLKTLALEKNQLTKLPDSIGDFHQITELYVRENQLESLPDGIRGLGQIESLYLEDNKLTADGIPESIAELAETMTGLCLHRNLLTTLPVSICQLTNLEELYLNENAIESLPEELGQLVNLRELDILGNKLQTLPTSFRNLSNLEILHAENNQLVKLPKGMGGLTSLKKVYLQNNKLTKLHSSLGRCVKLEVLNVEDNCLQKVAKRIGELPKLKHLLLANNQITELPFNPLEKAPGLRRLTLSGNALPVETLALEQKVTLNQVAEGEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSL0</accession>
    <name>A0A8K1CSL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSL0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422802" evidence="2">
        <location>
            <begin position="28"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="337" mass="28909" checksum="E227EE6B227EA7ED" modified="2022-08-03" version="1">MVQIKSTISLYLVAVTLAAVNVPGVHAEEMTFAGYGGGKASGSTSLRGTGYGYGGASGYGGVSGGVSGGAGVGFGAGLGGAIQAGLNAVGKLAGGLGASMNGGYGGKAGVGAGASVGVGIGGKAGVGAGIGAGAGINAGIGAGAGVGVGGKAGVGAGINTGIGAGAGINAGAGVGIGGKAGVGAGIGAGAGIGAGAGVGASAGINAGVGVGAGVGVGVGGKAGVGVGIGAGAGIGAGASIGAGAGIGGGANGQIGGGAGGNGNGNGNGNGNGNGNAGGQYDGDSKPPTSSAPTPTTAPVVNEGGDNASQQPVGLTPAPTDCDKSKTDSPVTPEPSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSN8</accession>
    <name>A0A8K1CSN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSN8"/>
    <dbReference type="OrthoDB" id="79090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055309">
        <property type="entry name" value="Znf318-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15577">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15577:SF2">
        <property type="entry name" value="ZINC FINGER PROTEIN 318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="944" mass="111935" checksum="2F95BEE518144898" modified="2022-08-03" version="1">MAESINASGATAEAPAPLAASVRPPPSEREHNGSSGRKRSRSNEQSARQTERGSTREQSTPSRSTSGRGDGTPAGYRANVPSSGDRRRNVMGESSRTPTPLRTSGGGGGKSPASSRVIVSSNIMLSDSQWEQEIAEFGRILDDMLTRVSNRELVKQTADYMRAWPQHSVRFQIKMKQRAYGETARQFSSKLMLFYVFHEFLKSFEGDELRLIQREWYQTVDEILHACVRDIKNNEDGRKRLFKTLARWEELGIFVHKIKQWKSLVMGETKPRRAPMLLPRNEAERLAEAPDQLQQFPPPPSQPQLQINRTNYPFVFERSNFRTAFDRKQHWRFTSVAFIEVLGQCLGLSRDITLTAAMFFHRVYDRGIYAQERYKFAAACIFLSAKAASKRMKLLRMVKTMHEILETPLLAGDEELLDLERMQLLYYEIEVLKGVGFELTTDLPFYYMRQTLDQMSEKFRRDIEDAAHSVLEELFWLPLCLTTRSQFLAEAAAYIACRNKDRIFSFKWCREDKDGKVLTEKAAKDILKEYRGLIDWKKTQQSHFDAFLKTAGGQSSNDLNEAFKVQRQGLRVDVTQIQVEEEYTEKGKNESKEVLATYVDEEAEQRQQNRNRSSYSSRSTQGHRDDVKVKEESSRYQSSRGRGDDRDDRSRRNDYSRDRERDRDGVRNRDRDNDYNRDRGNNRNRDRDNDYSRDRDRDNDRNRERDRDNDRDRDRDRDRGRERERDRDRDQEKSYDKERERNRDRDRDRDRDRTREREFDRDNDRDRRYIKEERNGDHGSDRRDRSPRKEDRREKDSERERDQDRTKERDRDRSDRDRDRPRDSYRDRKDRDDDRSRTTSSSRRTSRSRSPDTRKRKYRSTSRSRERSSHSRSVSPSAERKNKNGSSSRPKHSRSSSRERDRDRDRDRDRGRDRDNDRRRVNDQRSVKRSDYSSVRIKDEMPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTB4</accession>
    <name>A0A8K1CTB4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTB4"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000077">
        <property type="entry name" value="Centrin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="116" mass="13495" checksum="14DF4880500F081C" modified="2022-08-03" version="1">MRALGFQVTKKEVIALVDDVDVHRSGRVEFNDYMEIMRRKVLARDPDEEIARAFQLFDEDGTGKITLRKMRRVAKELGENLGDDELQAMIDEFDQNQDGEIDMSEFFAIMKQSTEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTV1</accession>
    <name>A0A8K1CTV1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTV1"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20981" checksum="73264A17C2E887B7" modified="2022-08-03" version="1">MLKLRQQVVRRVAAQRALNWDALSTKLTDPRARAALDSLRNLHGEIQNEARQFVNEPEAIDFEYYRSVIKNKDLVNAMEENYKNIVFPTITPEDLDKVSADAPEALRLNEQETIDQLFAQLNEKVEDSKKRIVELQEVVALLEQTRTTLDTTMDEVAAMYPEVGEEIDDEIANFEWEKDTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUL6</accession>
    <name>A0A8K1CUL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUL6"/>
    <dbReference type="OrthoDB" id="161703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052942">
        <property type="entry name" value="LPS_cholinephosphotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43404">
        <property type="entry name" value="LIPOPOLYSACCHARIDE CHOLINEPHOSPHOTRANSFERASE LICD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43404:SF1">
        <property type="entry name" value="MNN4P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="23739" checksum="E0806A319BBBCA38" modified="2022-08-03" version="1">MKNEVVEAYFDPVACVTQEERRERIVALVKAVDRLLTQLDIDYWLDSGTLLGQFREQNVMLWDNDADIGITSAGYEKLRGLKVPVDVPDGYKLQVYDSELYDTDDRDANIPVRLVDTRFGFYVDGFVFHEAVVNDVEVLSTAASVSWHTCAKCLRVGTYEALLVITKAYVFPLIACDFADFRVVCPAQRTLYLDHLYGSDFRIPKPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAP9</accession>
    <name>A0A8K1FAP9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAP9"/>
    <dbReference type="OrthoDB" id="5876637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="210" mass="24206" checksum="854BA3FC2C12682C" modified="2022-08-03" version="1">MGRVSSKRKIKQCDPFFKGSRDNGKKGKEYDLPPTESKSSKKRKRKYMSDEAIEQYVIRSSEVNNGTVALDKQAKKKKKLDGVGTIRENETMKDFNKRINTEVKRVIYEESKKTRRKSEKRKDFLQKKKEKEKQKKMTDQERYEQEYQVSGSTKRDTFAGVEKVRFGERVDAPPIMPKLKGIFKKRADAAAAAAQKKAKKGGPPAKKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBJ0</accession>
    <name>A0A8K1FBJ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBJ0"/>
    <dbReference type="OrthoDB" id="73411at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="380" mass="43293" checksum="D329792982A04D94" modified="2022-08-03" version="1">MEARVVREYERLLVHRRRFVLGEVVQCLKMISESLESLEVLVTDDMGDVASHLGVMTKQMPVFLGDTDLQVFHRSLTAFVSRVELCHSEQVALEDSEKAIAKSISQVIRTLKQQIVVFEVAVEAASPTASAIRHKREHLISFLEEATKLLTKSHSSQRTAFQVRKDELLLEFQDAVQNEALRDIKQIKHDLLAIESSATEMLARHFEICRTIVVANAQVADDGVFNDSERQHIQAFVQSMMQVDGGIFALTSTNEEADTFFRQLEFFEKAAEQDAFLVYSSALKLQFREQLDQELFRAYLDDWESKKNELSDLEDSEEYTAALERVSALKRDILRVQTLVLHSQENEALDNPLKSQLQEELRRVFVEEGGELGVTLAVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCB8</accession>
    <name>A0A8K1FCB8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCB8"/>
    <dbReference type="OrthoDB" id="121615at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="19300" checksum="836857D9029AF7E2" modified="2022-08-03" version="1">MSPLLKLALKNYFSVMLRQLDDLKPAIVVLNVDVFSALYVANILQASQSRVNTAIVLAVDVVQMAIAVDDLRMVMSEIQSLVRLDKFNGSVLDLCVMASSMTGMRKELDRRSSSSRTMSLASKRTITPADGRTVIPPRSEVPAAHPSRLSMKRWLLRGSSQTTPFDSSIPSPGFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCM3</accession>
    <name>A0A8K1FCM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AGC protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010029</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCM3"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000537">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053858">
        <property type="entry name" value="Arb2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22749">
        <property type="entry name" value="Arb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="517"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="775"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="467"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="94851" checksum="2053C12418216014" modified="2022-08-03" version="1">MADTRRVFVQLAKIVNGQLHMSTPGMAFVAASDPWLTTVNECVMSCYGDEIEVPNRPAGMLEKCRVLHASTLQQITDPHMFEEGKQYILCVSPADFEAILRKSGIPIPGASNGAAAGRGSDDRMSIATTDTLESLEELSYYFDDVGTLRHCSTNQAVYEMMNDELSVSEMDEIVKAAIFHVQMEMLAELSFKQAHLPLDPRPDEPKEAKSSVFLTSDWKSNNNLMVVINGGRGVQPGIWSRDLLIQEGLELGSMLPVFRRAQTKEFAVAVLNPFTNSVMIGNDSHQIRHNASPDEHTLYVWDNIISRSRAQNIYILAYSFGAKLVTTLLQNREAQAVQKIKAVVFAEAAYHIDPESTSPMVGQFLRQRAINFKADAQAAVGSHITSAEEQLCCSCLSVGNLAASTDPSTSRRGSSNKARTISLCLETTFTYFAAARDKNFGAHQFISESETKTRSWLGNMIRSRIESIKPRKQSRRMSNMPDGPHRKSARRSSSDSSSAMRPSSLGSPPSNISVSDFDLIKVIGKGSIGKVFLVRKVDTHIVYAMKVLRKKNVVRHGLQEHIKTERLILEEIDHPFIARLRYSFQTKDKLYLVTDYCSGGELFHHMSDNGFSYELSQFYCAELVLGLAHLHKLKVAYRDLKPENVLVEATGHLRITDFGLSKLNVVSDEGAQTLVGSPEYLAPEIYSMQKYGYAVDWWSLGVFIFEMLTGVHPFYDDNREVMMRKIMTPGIIKEIMPPTMPRDAATLIEGLLEFNPSQRLGSRGAEEIRSHPFFQNIDWDKLVRKEIEPPWRPLVRNELDVGNFDPEFTSEPVVDSVCTAQSMGLSSTFDNFTFDPSGGSIRRSSGSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD67</accession>
    <name>A0A8K1FD67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD67"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17671">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="7">
        <location>
            <begin position="78"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="6">
        <location>
            <begin position="332"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="8">
        <location>
            <begin position="834"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="784"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="786"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1026" mass="114249" checksum="CB2A0FF50FAFF0EC" modified="2022-08-03" version="1">MLSRVTQWLATKLEYKEDDHLRTRFDALTRMKKATLDLLNVLEERSTADNEGDEGGDGLAQTATGYLASIASSRVVLTEEDQCVHDFGAALENCLKLGIKGQNDRDLSWWQVLYTSTLMVDDPTLVQTIQTAGTMSETEVGKARCWMKLALNNRTIESSIAIICSQSCEPVVRANYEDWALVRCIEGLDIFMQMIADIRDVRFCIRVDEEPFRLPIAKEVPTIPIPGAGAESAKAEGDAFAATTTSTLAPTTPTATSASLPISPSPSDVTVSADKLGQPETAGHPLIPDDDFFVEVSAVVFPHRHKGIKPWQHVFGVSIAYLAKNPYHSRFALIDPVLSIPNIVQDCIDILYENPNTPRLFRTTVLNVTVSQLREIVENEGMLPADLDAHGAGALLLDFFKNLPESLLTTEKYEAFIASGRIKEEDACIRNIACLVQNLPVHCKFVLEKVIAVMHFLQLPEHSVHNGLDVGLASTMLAPVIAFKSETKTTPAGQRKMSHPQHHDVRFAAIGAQVVERMIVHHDEIFQEVRIQVSDSLQRLETKKQALLSIYQLYKMKPQVNFFSDRLHLDEISDIFVESVKSKESLSAESPPNNFDRIPPPVLRMKIGSPLKHRASSPNLYEGVLSSSSAQGVPIPSLGYAGSRTGSGTYMVKNDSTMLLDRLYNRALPTVISSYDAGLVSSAICKSLINLLKLVPLPENPTINIVALSVEPFWELFDEEAYFFKLFLLVFQIFDQLWNSLSPDEASFTRVFCDTESKVDELLKKSPSSVEDLRSEWEGMWRQMNEEEEGSTEEESTTTQNATAAPPSPPRLCKKPSFTFRPEDYKNKLLDPSNILTVDHIAFIDHAVPLTCQLCRWCLLYSTDMHGSSLHTLLMMTKNQSPTLIVVKDDQDNIFGGFGSDEWHRSTQYFGNGETFLFTFSPRAGVPTAHSGTVGSHFVKYPWSRRNNYFMLCSEESLVMGGGGSFGLYLDSDLSRGTTGPCETFSSRPLVPSHEFNCVHVEVWGFTTSDKHPTANKEKKRRSVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDM5</accession>
    <name>A0A8K1FDM5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDM5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="17300" checksum="71D7CADBA061FA72" modified="2022-08-03" version="1">MFYLFQDGVVRETLQLNSGTQSLLMDNNVQEMALQLSIPSKSVRLTVIGCGLLCLGAIFVAAYSVMRRGDPLATVSTPQGIAQVMVGETTYPPWVLHRKLVAGSDREDADAFVVGRISLNNHQSKKCVEFDESMPQTASSNTSSESSVEVTEIDVQCQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDQ0</accession>
    <name>A0A8K1FDQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDQ0"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000507">
        <property type="entry name" value="Exportin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="964" mass="108988" checksum="1EE8355E8690D679" modified="2022-08-03" version="1">MADPNMLRSSLEQTLSPFAETRKGAEKFLESVSGQPGFVLVVLQVLESAQEKPEVRLASALLFKNFIKKNWDPEKEGCIPETEKQVVKQHIVELMCRMPESIQKQLIEALATIGEYDFPHNWQSLLVELVQKLKTEVDWQVRIGVLMTANTIFKRFRNVFRSDSLFAELKHCLEVFQEPLLVLYKETGAALRSPGVPKAQQLQIMAALRIMSRIYFSLNWQDLPEYFEDHIAEWMTEFLSYYDYVNPALIDQDNEDEPDPIDLLLVAIADNVNLYADKYDEEFKPYLPKFTEVIWHLLAKRITLNPKHDDLAAKSMKFLTLVSSRSLHRDVFNSQQVLTEICGIVVKNLQLRSSDEELFEDNPMDYIRRDVDGADGDSRRSAARDLVRGLLNSFSDDVTQICMSTIQTQLQQYRANPASNWALKDVSINLVIAISALKQSRLRGVSEVNSRVPLMDFFMGEVLPELSNPQVSPILKAGAIKFVSTFRNQLPVEAMEQLFPLLMSCMEPAQFVVHTYAAACVERLFTVKDNGALRFSKERLAPYLEKLLDHLFNILEQPNYPENDYLMRLVMRLISVAKQDVIPLADRVVDRLTRILKQICANPSNPTFSHYLFEALSVLILNVCSANPAATERFESLLFPPFQTVLANDVEALSPYVYQVLAQMLELRPSGVSQAYMSMFPVLLSPALWERVSNAPAIVKLLEAYMRKAPNDVSQSTAGILGVFQKLISSRTTEAFGFSILRAMFTFMPQEAFKNFYSEIVKILMIRLQSRMSGRSPASFVIDLLHTISVAIGKLGADAFVGALEALQPGMSKMFLVSVWAENATKVRGRNEKKACVIGLTRLLCESELCKSQLDVWKSTLEATVKVLEDVEDSSSLVRDNDDVLEDLEQTGYEAGFSKLHFASIVPTDCLSEYPEGKNYFVTSLAKLSASQPGVYSAVAQKELPPQAVEILQGYFTQYNAHFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEB8</accession>
    <name>A0A8K1FEB8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal peptidase complex catalytic subunit SEC11</fullName>
            <ecNumber evidence="4">3.4.21.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Signal peptidase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase complex catalytic subunit sec11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_014397</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S26B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEB8"/>
    <dbReference type="OrthoDB" id="10257561at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00728">
        <property type="entry name" value="SIGNALPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S24/S26A/S26B/S26C" evidence="17">
        <location>
            <begin position="38"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW57794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="182" mass="20748" checksum="2CCA38D9D579F4EA" modified="2022-08-03" version="1">MDLVKQQVDEAKRIWKNKRQLSHQVLNLAMVMLTAFMIWKGLMMHTQSESPVVVVLSGSMEPAFQRGDILYLDNNKPQLDIGDIVVYKVKGRDVPIVHRVLEKHQRTSDGHEVYLTKGDNNNVDDRGLYAHGQIWLEREDVVGIARASVPYAGMLTILLNDYPFLKYVLVGGMAVLVFTQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FED3</accession>
    <name>A0A8K1FED3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014442</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FED3"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF9">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="584"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="624"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="670"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="38"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="720" mass="79197" checksum="09D8653FB5E74C78" modified="2022-08-03" version="1">MGGGGFHLPSANDEVRMTEKEERRERFMQQTRAEASYLFKYLIITQVFIYLEAGAIPCLLDQLSVDLHMSATQQGALGGVVYFSLSAASPLCAYLLHRFNPRHVLGASLVLNNLATLVLALTPTGYAFSANLMIIARALIGFTQSFPCIYTPLWVDEYAPREKVAGWMSYLQGSVPMGVMLGYFVGTVANWFVPESFRWFQTWRWPFLVQFIAMCPIMIAIFFVPKKHLIIRSEGQKSSPSSRASSSSTTGSTDLVSEANQSIETAEDILAAAAEAVVAEQVELTMQSIKTNELAPLINDNTTFERVRSKRQSRSRLSDSNNRIISYIEETIKLGANPTFSWSGPNHEEEDVLLASASMYGGTSQRGIRQLHHNQQHQQLENDVGSSSLRRSFAGSMLSGTTDGSPEIPKLSPGVNSLTVTRVGSSNAPHSSSGYGAFDVAIPETPQKSPTVNLLEASMLDDDFMDEYEEGSFTEGIRTLLQIPIFCLIVGGLTAVYFVVTGVQYWSTIFMIKSLHASKYIVNALFVFVAGTGPIFGVFFGGWLIDRCGGYIGIEQRAKALGICMVLGIIAFIVSAATTFFDDIYITAAFLWLLLFFGGSILPACTGIFISVVPAQHRAVASSFSVMIFNLIGYALSPYLTGIVMAWVLAKQGEKDSYFELCDEACAYRIGFRFCLFWSIGSIICIGCAWYIARREAAAKAKEELEFYAALKPYVPCEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF76</accession>
    <name>A0A8K1FF76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF76"/>
    <dbReference type="OrthoDB" id="435413at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="841" mass="95530" checksum="7B64A08D549FC77E" modified="2022-08-03" version="1">MVNPMKDIVIGTGLGVSLALVWKNYKKTYFERVDSYYKWYDAEQAKKLFSIQSGMKLYVHYEDGTSAWTKRLTVENLTTTLEEVLTRFSSAYRAKFTRDLSLTSCRVFVERNQDTLTRKLITTDKYKQRLDQFSGINDTSAIEFVIVAAAPAKAHKEGELPAKKQPVHCHMKAPPSNELRVLDSDVKDGLEIAASQIAAKQYVLAKDTYEMLVFPSDPKNPEASLAMGTMYLTIDKPKAAVDKYLLPCWEGHREHSRDKASERVVFNVAIKLVECLISQHRYKKALSVLDQAQQYVRQRARHRGWFSDMAEKDRAEARMDYLRANALYDLKTQTDQETAISLLLHLLPDLQAADVNLDALQLYARIAQDRGKKNEAVSMLFRVLVGKSKDKTVRKQLVDLLRGKKGMERLVQAIPVTDQSAAVAYAYVATILKDFGAIDVAVLCFRQALQIVPTSATYALNLAHALEACNRYEEAYNALVRFFQSNRGLSVGGVANAGEVVDALARNGWKFQSSDSAEFSRWKLIWKPTSGQQGRVDVYENGSLCQKQRKNAFPTRASLTEDELDLLATFFAVVKILFLNGRLAALPRLIGLLEPIRAGRELHTTMIRNEQAYYVCIAQLLCISPFLKQPNVPDSHRLVHATAERNAHTYVCGDSHTLATAWREIQLQGSPVILQPALVTGLKHWHLRPESQFYPKINFWNVLEALPRHSRVIFLLGEIDCREGILRAVQMCKYETVEEGMKHTASIFMEAVTEVVKRFGLEVFIHPIVPVLKETRHLVIQYNQILRDRVNKSNNSTWLDFFDDLLEGSPAKLRSCYELDGTHLHPSYLQVLERELSKHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFU6</accession>
    <name>A0A8K1FFU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFU6"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07087">
        <property type="entry name" value="ALDH_F3-13-14_CALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="48"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="553" mass="61857" checksum="8729F6903327E105" modified="2022-08-03" version="1">MTSSPVSPATSKDHQYIAVAESSTDAARAKNKFEYPLDAMYGSILNYEFPDVTKQDTAADVQALRETFRSGATRDLKQRRELLLQLQRLMKEGEAMMKEAAWKDLHKHPTETYACEISLINQEIQDFLDHLEDWSKPEMTLTSLTNLPGLSYICRDPLGVVCVVSTWNYPINLLFMPLIPALAAGNCVLLRLPGDDTTRYLNNVFITLLDKYMDKRFVRYVYGGVEETKAMLRERYDLIFATGGGFLGKIIARSAAEYLTPMVLELGGKSPAIIDETVDITIAARRLTWGAFTNAGQTCVRPDYLLVDERVGDKLVAEIEKNVRAFYGEDPKESNGYGRIVNARAFARLNTIVQADKARITFGGVADEKESYISPTMLNFKTDLDGFVSSKAMEDELFGPLLPIYYYPAGKLQAAIDFVSAREKPLALYFYSTNSKNKQRVVRETTAGSMVINDSMMQLSNPHLPFGGVGSSGMGAYHGRHGFDAFSHRKAVMYKYSLLDLPARYMPYTAASERMLRLLLYPVSRRQLRVVKLLGLAVVLVAIGFIIKAAVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHE6</accession>
    <name>A0A8K1FHE6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHE6"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="27214" checksum="C0033922691B6FD1" modified="2022-08-03" version="1">MLRASLLFQRTSVVGARRMPSAFQPHRFASTKASSANGGFFKSAWTSYSRLLETKPVTTKVVTACTIAGLGDVTCQFIIEKSDKLDVKRTAIFTFLGGVVVAPILHVWYRFMSTTIPGLGTQAVLKRLAMDQLGFAPTFLPIFFTMLLTLEGVPETIPEKVRTEWWPTTKANWVVWVPAQLINFRFVPGNLQVLFANFVGFFWNSYLSYVSHATTPKIEAILEDAGHADHIGHDGHAGHLEHAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHP5</accession>
    <name>A0A8K1FHP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013692</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHP5"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001480">
        <property type="entry name" value="ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="600"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="39"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="631" mass="70327" checksum="AB4E4A13DF4B457A" modified="2022-08-03" version="1">MSTQPLNIEHMQEPQHFIQIETPKVGGSKYATNAPKLTLQWHNLTLKASAKNPQTKQVEEKVILNDVSGYAKPGELLVIMGPSGAGKSSLLDCISGRKSGVEGSITVNGAPWSKQLKRLTSYVMQDDLFYATITVREHLMFQAQLRMGKTHTVEEYTQRVETVMEELGLNKSRDTLIGNESIRGISGGERKRLSFATEILTNPSLLFVDEPTSGLDSFMAETVVLQLQQIARDGRTVIATIHQPSSEIFTLFDKLYLVSDGSAAYHGKASESVQYFASLGYQCPSFMNPSDYFMRQLVVMDKATDQAGVERIERLKLEWKKRSHEAVGQIVPQSEIVASKNDDTDYDGSRLGMAGQMLVLARRNVLRFYRDPMALRISAFVSVFIALIVGLIFLQLDRNQKGIQNFAGAFFFITVNELFNAANPAFLSVPLEIPIIEREYNTGLYRLLSWYISKNISELPTQIILPVLFFVPTYFLIGIGGGFDVFIAMQAILILINSCAIGLGYMVSCLTRRVDIAPIVGTMVTLPFILFGGLLINSDTTPDYFIWVQYISPVKYGNEALMKIFWGQIDSISCDAAIENCSALTGADVLRNYSMESRSALGNAMILLAINFAFRVIGFVALYRHFNQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW7</accession>
    <name>A0A8K1FHW7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_012972</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW7"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02930">
        <property type="entry name" value="DCR_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000082">
        <property type="entry name" value="NADPH-dependent 2,4-dienoyl-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000113">
        <property type="entry name" value="NADPH-dependent 2,4-dienoyl-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051793">
        <property type="entry name" value="NADH:flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42917">
        <property type="entry name" value="2,4-DIENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42917:SF2">
        <property type="entry name" value="2,4-DIENOYL-COA REDUCTASE [(2E)-ENOYL-COA-PRODUCING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="377"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="76582" checksum="247CB271F4115708" modified="2022-08-03" version="1">MASKYEHLLKPLDLGFTTLKNRVLMGAMHTGLEDTRSLTRLAAYFAERARGDVGLMVTGGVAPNRAGRVSPLSAKLVTRSEVDAHKEVTTAVHENDGKIAMQILHTGRYGYHPFTVAPSPIKGPASWFTPRELSHKEIVTTIRGYAQCAANAKEAGYDGVEIMGSEGYLINQFIAEHTNKRTDEWGGSYANRIRFPLEIIKAIRQAVGKDFIIIYRLSMIDLIEKGSTWEEIVELAQQIEAAGVTIINTGIGWHEARIPTIATSVPRGGFAWVTKKMMGEVNIPLVTSNRINTPDVGDRIIGEGYADMISMARPLLADPFFVKKVKEGRADQINTCIGCNQACIDHSFQSITATCVVNPRSGYETELNFLPTKTPLRIAVVGAGPSGLAVSTLAAQRGHNVTIFEQTSEIGGQFNMAKVIPGKEEYAETIRYFHKQLELTNVDVKLGHRVTAEELIAAGYDRVVIATGVEPRALSIPGADHPKVVNYVDVLKHNVSVGKKVAVVGAGGVGFDVARYLTHEGVSPALDVGLFTKEWGIDMKNEARGGVAGLTTEVPPPAREVYLLQRQKSKHGKDLGKTTGWIHRASLKNRDVKMIGGVQYNKVDDAGLHYTDKKGKEQVLDVDTVVVCTGRMPLRELEEPLKKAGVTVFRVGSADESGEHDAKRAIDQAARLAAQIETAKPGEVLQADLPLSSKLFALLGKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI81</accession>
    <name>A0A8K1FI81_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004542</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI81"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461283" description="alpha-1,2-Mannosidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="9">
        <location>
            <begin position="649"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="775" mass="85753" checksum="21F1B833226B7FF6" modified="2022-08-03" version="1">MRSWAARVLSLLGCVLVVFTASVAVEARMHASEMRYLRDKARDMFYHGYQSYMEHAFPWDELKPLSCEGRRWDRRERGDLDDVLGGYALTLIDSLDMLAVLGDRDEFHRAVRLVIDNVSFDRDVTVSVFESTIRVIGGLISAHLIASPAHLGVLTADEYKGELLDLAVDMGNRLLPAFETPTQLPVHRVNLKRGMLKHAPAMTCPAAAGSLLVEFAYLSRLSGNPVFEEKAKRAVVGLWWRRSEINLLGSSIDVFSGEWLTSHVGIGAGLDSYFEYLLKYHLLSGDKSWFDMFLASYRAVETHINHDDFHIEVDMHHGRQAVRSRRVSALQAFWPGLQVLAGDVSRAMRSHDKLFLLWNQFGAMPELVDLLSNEDGTTTSGSVISWARTSPLRPELIESTYHLYQATRDHKYLKIGRKLLEDIERVSRVDCGYAAVGNIHTLAVEDRMDSYFLSETVKYLYLLFSEDPDVIVPAMPLPPTNSTPIQVDSEVKVPEDEEDVPALTPDDSAVPTCACRKNTTNQTLVESSLISTKPQWSRPLKTADVVFTTEGHVLMMDTALFTRNGSDSSSKQEVFACENGNALVTQQRRQLPTPTSTESLTSVLPIGVSVRLEDMHVLTLVGAPASFGKLLGRDGTHVDAPLLLSTEKVGDACSPLLDETGEMVRGRVVMVARGGCAFAEKALHVQAAGGRGVIIVNRHRKKPKKTDRRYVITDDKRGLGGHVTIPLLMISAEDASLLKRQVSAMRAAAEAAEGDDGQCLTEGTSLVVSLSAWLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIB8</accession>
    <name>A0A8K1FIB8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIB8"/>
    <dbReference type="OrthoDB" id="165257at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="298" mass="33940" checksum="86D1967E4D8C6EE2" modified="2022-08-03" version="1">MMLELMHSTTAVLLGGWSEVQIALLVLGVLVVAVALLSYFVIAPEYEKHLEKQYAAIVHQTTKHHISNMAKKTPLSRSTSMGKDPEGYRAVQRVEATFREATIPENIDRTETVEWNRRHSGPAIPAMAGFDLNRRRKSESDAVLRMKAEMLRRRVMLCKIEREIDGAIQETEEKTFGLPTRRTSFRMARQNTSRTLGLSDEQLKVIQEHPADCTTELQVLAKTQDAATIRKVLRILHDVISFYLSVDHRDVNKVTVFCNSLIKHDSLNHLQSLRISNDAEVRRLANQIIEKAVPAIWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIH1</accession>
    <name>A0A8K1FIH1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIH1"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="22"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="153"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="38447" checksum="8AA8FC5C234FD701" modified="2022-08-03" version="1">MDLIQASFQASFNAQIERLVEQETAELRTIFRYFDSDGDGAVSADQACRIFNLLGLDVNPSQVRDLEDVYMAEFMKIVDSHIPAATNVDSDAVPTVVGEAPKQEPSHPTVNAAPPAVAQPEGTPVNPSNGPQGATENGQVPPVGEDESAVQKRNEQLWEDEWKVIDSYRRGFVTSDELRLFLKSCFSPFPIRDLPRFLELYADPSVPEDDMMLTKVSFLKFRQEYTTRDQAGSDRGLASEDEDDAENENDDLRFSVDQHTTGRSDTKSGGEGASQANTRRGGRRRRSSLGLLNADTGVDGIIVDAGVLDQSDEDYVDEDDLRDEDNAMTSRADAYTPLPHELHPDDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIM6</accession>
    <name>A0A8K1FIM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIM6"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000144">
        <property type="entry name" value="Beta-glucan synthesis-associated protein SKN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480604" evidence="5">
        <location>
            <begin position="23"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="683" mass="75903" checksum="177B0EE1C4A5C53B" modified="2022-08-03" version="1">MKLDVTILGFLVASSWDHGVVSTYKEYPTKSGIKMWVDPATPTDRQQCTNSRGRTWELVMSDEFNEPGRDFRPGKDHIWTSLEKPDGVNGALELYSHNMTSTKCDDDGTCYFYIKVVDDPQTIRTYNMYLNPPAFQNVEFYYRAAMVQSWNKFCFQGGMLEVRSQLPGAVSKKSGNPDLKDGPNSRVKTVGYYPTWPGRGAPEIDVLEGNGLDVSSSLQIAPGMPMDFRMFPPESVDCVYTANCRTPGANHPGVPTALYDKRGHKSWYQGLRYGPSPFCKPDPSKVQDYKTVYNTMKSGITKNTCGVDNCPASKDGNAEVSLIDGVGPGYWGINQNGSCYPMINGYTGAYLCDPDNQHESCAKPRPDDQPKSNIMDPFNYQIDAISSNWHLHLGAYLDYVVYQVEWVTGMNGYVRWMLEGHPLFEITAEAFSKVPQDKAKSNPEKIMLEEPMYMIMNVALSSSWVFLMLEEPMYMIMNVALSPLQIQASPAVVDYVRLYQDLGDDRDADNLMQLSCDPPSHPTREWILGHIDEYQDWDSPVKDVAGGAYCTIDDDCTIGTSNSTPAIRLTTGQCEKSRCKCTHGDSWGGPRCTTAMRGTQYGASKTTVTGFGPPMELAIAMAALVVLLTTLSVWQSNKKEAAEARARAKAVAMTVTKPLQVPSPNDGIGPAKVDYNRNFVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIM7</accession>
    <name>A0A8K1FIM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIM7"/>
    <dbReference type="OrthoDB" id="160135at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="204" mass="22206" checksum="868E04032D07A77E" modified="2022-08-03" version="1">MLSQLSLHDEQTAAKALQNLRPGLDVWLSPSSPTSPSMTSEPSPRSPSLTCPQSHKCSLAFILSDPAPAEEHEEISTEEEDESKPRALKHKRRAPTGSKSKYCIVEGCTSRAKHARRCWRHGGSVKCKVPECINRAKSRGVCWSHGGGTTCTHPDCGTIAVSHGFCWAHGGGKRCQVSGCSRPAYERTQNFCSMHFKQGAESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ49</accession>
    <name>A0A8K1FJ49_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012618</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ49"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="215"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="870" mass="99063" checksum="8E55CDC4EB5A97D5" modified="2022-08-03" version="1">MATHAALDQDEQRSDGPSSRPSSRPSSKKSTASAQRRGGNNAGPHSFYKLNPLQIAAVLKTFWVELLQSNLKQVKKIVHENYQAMDFNAARYAPNADGSPMHLCAQFGHVNFAKVLGTYGLALETRNKVGSTPLHVACKFGQTGVVTWLLEQGVQVDLPDQQLRTAFDIAPYNVLDCCVLAPLRNEHTRLTQREAELTETHRVAIAEYDEAQLVFRQTEMVLADLESQIEEERLRIERTSAQERDWDQQKLAALGRQEAMQKHYERNRRKLREEEVATQDLYDLTIRAVAEEKQAAQAEYERLQGVVKANQAEQEAREKFLVEQLGLYDAALVDFPDNRDIQLWVLMSLRILTEQHDNIDAVLRGEAIQIVHHQFLHFQHDLEVLRAAALLLITLLRLWEQQQGVISTVVEPNEFVSTIERGDLMVRIAQSLTRWPISTDGLDLIHINGLEALYAAIRVIKNTQRVLAMCQLKPFQGFIMQILRVLLEDPSNLETRPQTTCHAVFMALTMAKYGVRKPLLREGLVRTVIAHVERVSERLFDSDDSCEWQIEMLHHALRLLTMLHQPNGASRHDPRTVSTLDEASDIESISIRVVTRCLMCVRPFTSSQHSCLVVFWSFKFIHGLLRHVGTQAFRLRRELVNEDDALGVIMQSTLNVLDNEPLGRSQDSLSVVQASVELVETAWIHQFDSEGQLQPCPERVLGFLVDLLPYQLRKLECYRHNEAWHSVLLIETASILRPISQIAAAVLNRASLVYLYSRDSELTDSTQQLLRWIVEFVAETHVSFKEPSVLQVLVPLLRLHLARCQFLQRQERHSSTQLHAWSHNMGVCAIIKVFEQKEEATADPKELVPREWETLGALTYALGLVINTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJG7</accession>
    <name>A0A8K1FJG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJG7"/>
    <dbReference type="OrthoDB" id="78779at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1038" mass="114707" checksum="B6448C3BC71A50BE" modified="2022-08-03" version="1">METEDVTFVPLMRPEGPRSGGHVTIALYAGMTAKELQAVVRAALGLPAGTTCSGFIVSPQGDATGKKKQPQLRPSAPTAELSSSRQGGVLRERVVPLTVACVSPEVLTATGGSVKVLLSSTGSTARKPRAPVVAPIPPTRGSHAAASVSTSQDKETIERLQRLINALREDDKSISSFEAAVLAEICEQRAHEVLTTVRGHQSVATKKQYLLSLVRSPEPADATPALAPPLPMTVRSNGEATSEASAQIDLICKKVVSIAHTVFSPHVQSDLMTEASLYREKYRKIHAHNARNRSTNGASSTVAAPVNVSSIMELLGVVERLLNKHALQEEQSVKLIRLILAENRLLVSALQSYKLDFNLNELEHTIKRMAALGGSASAPTVGDIPTEAKKTSRPSSRHSSPRKTKRKDRKGFIVRPHDILHTLYQKQMITTLELDLLRALVTQNDSQVLAAVDEYEQTRRLGSLRDHLVNIVGEITQELGDDERYAALMRSSMEEDPDQALAAALNNWQENLIQFVQRWFSERKLTLEHVQVLRALIEENHNLLQSSYEVFVTDEDENELLDTLSRIAKLQLQAQEGTRLLAFTQVVEEHCDVLRGHEKTLVKQLFARKNELVRAAWEVFEVERNVEDFGDTLLRIARFTTRQDSKVRIVEVVGEMMRRQLIRSHEADGLLRLFEEKNDAMVAAKEAFESDGDVTELVETLLLIVKHANFGEPPICSPRNAVPKTPPSSPVIPDRVEEEQAVATRLIEILCSSGRLAQWQADLLLALLVRGDERVLAVMDVYNDDRDARELVDTLWRLCDLTAWEQNRGRIVSEWIEPLEVSGQVPKGVLQKLVNARDDRLVAAFVVFLGDGNGAEFSDTLAHLGRIVAKQPLRLRKASNVEQATEPLVDEQVTQVLDTLVFEGALSADVREQVSARINAKDAAALAALDVYAETQDVQDLADTLQRILTRRQRKTSDTNATPLSPTRASVMEKQLLHFASELELASGELVALKRAIARRDSTVEAVVQVYSTETQNEEELKNTLRSIAANLAVASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJN0</accession>
    <name>A0A8K1FJN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJN0"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="33211" checksum="94BC591B8DE326E9" modified="2022-08-03" version="1">MFISFKIYNIFLCIILFGMMKTLNSTSFQIRQNPHKVGNYGGIPKIATFWRSELMCDLITILLMLTACGHVLGTLLMLTRFRKIADNGVMQLLQKRYFWVGWDALMAAKMLGLDPTRSTWMVDGKAVTRCPLGTLIQTLYQSGPSGFVHLAGDYIFTGSGFTAEPRKFRFPAKRAIAMGLCSGSNGSLYRKDDATEPESAFTLHRNTTHPTAMVAPVDPTGVTEPFLQKEKASIFDRDLKLVADGYMGKILLVDKAEPGAMTTNKDTGLREYVVCDALSTISILDIKGILGNEKKLRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK79</accession>
    <name>A0A8K1FK79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sepiapterin reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012659</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK79"/>
    <dbReference type="OrthoDB" id="153074at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004757">
        <property type="term" value="F:sepiapterin reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051721">
        <property type="entry name" value="Biopterin_syn/organic_redct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085:SF2">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="31925" checksum="16220EBCCD3D9253" modified="2022-08-03" version="1">MRSAVVITGASRGFGRCLALDFTREITAGDVDMFLLARHEGDLGETVRLVTEAWASKANAAESKLQTFVKTVDLGDQVDYVTKFDAILEQLQATAYDRVYLVHNAGSIGDLCFTQELPSPAELAQYWEFNVNSVVWFNKRFLDVYGATREELLSDAPLSASYQAFIVNISSGCAIKPFKTYGMYCTGKAAREMHHRVIATEQQPKQGTPKIRVVSYSPGPMDTDMQTLVRESSGVHPEMAAQFRKMKDDGTLIAPEVSSRLGVQHILMNEFESGAYVYYYDIAPGATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE7</accession>
    <name>A0A8K1FKE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE7"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052431">
        <property type="entry name" value="SKI2_subfamily_helicases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44533">
        <property type="entry name" value="DEAD/H RNA HELICASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44533:SF4">
        <property type="entry name" value="DEAD_H RNA HELICASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="245"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="493"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="669"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="504"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="672"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1107" mass="125613" checksum="DD411F1D4389FBBF" modified="2022-08-03" version="1">MAMKEDLRDVNWNKVWPDRMPVILRDLAPTNPFNPRNLWPEEKEEAAASKTSVSAAPEASDKAGKKGKKAEANGAPKLKKADLIRMQLAKDKLEKQSKVDEEKLANVKKSSNLLSMKMATPTGRLKQLYEILKECWKKKEFTDAVDTLWEIQRTQLMPVRSPIGVDGRKKSDKQRKAEEDEDARLQEELNAVHKKHRKYVKLVNDYLAGKDLIEFQLTEMSDRLPPLNMHHMNKFILDDWQRTVLTHIDQQHSVIVCAPTSSGKTVLSSYVSVVGGKVLFIVPTDPLAWQVAAIFQSMVKGTVALITEGTVFLPDEFKVAVGTPRAVESTLIDIGYDFEYAVYDEVHDLNGAEGDALERIIKAVTCPFLALSATIGNAERLLQWWKLHHPREIHLLEYKGRFINLQRMIWHEEQAKAEEEKKATKELVVLHPCAGITLEYLVKDGFESGDLSFTPRDTFALWKAMETYYPSEKIHDVAPQKFFQLSDQEEASAAAASTKDSKKDKKSKSKKEKSSKKSSKSKDDDSDDDGVVDLGTRSHRITLMESKQYEEAVKQRLQSLAKDEPDATQRLLDFFAPSEGLRNSMQDVTEGKDINGNSVDIYALINQLCLKSLTPAITFQLDSVRCRQLFNQLLASVEAAETAKYPNFREKVEAEYAEWEKNQAAAKKREAKVKAKDKEDEQREAQAFEERPPPDIYAPHPDFVLTPVGYRLSATEFKEIRWQLRRELSEESDDGHPLVRSLRRGIAIYAQNLPAGYLRLVQSLAQSGRLAVVFSDDSLAYGVNMPFRTCVFCEDTAEGVLTSLMVQQMAGRAGRRGLDRQGNLVFAGLSWDRIQFLMRGLLPDVNGKTSQYPTIALQRLLSSQMDGDIMNRIVAHPLTDFMATTQSEAPTSPRKQASYLAKSVKWMSSLELLTPEYKLNIDRSVAKLIWECRDDCAEAIGIYWILEAIFKEFQHKPGDVIANQLALFNMILRVVGREKYHSEFVHASVLAPLPGQEETWEIVGKLLVSYQEKLDALGEDAPEELHLRVALDDPLDGYVFRTIVDNLIPPGLGTFQLDLIKKRLRHVGDRLRLMHNLLMYSGRYGALEEIVRKCFRRIKWILIDSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKG8</accession>
    <name>A0A8K1FKG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKG8"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="14"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="36866" checksum="EC86ABECF6AE9BF5" modified="2022-08-03" version="1">MSAVEPRIVNAYAATKPGLEVEPFQYQARPLGLEDVEIAISHCGICGSDLHTISGGWGGANYPVVPGHEIVGTITSIGSDVKHLKVGDRVGVGAMVFSCLEKDTCKACATDLEPYCTKCVYTYNSKYADGQPSYGGYAEYVRVSGHYAFKIPEVIPSDVAAPLLCAGVTVYTPLKAHVKPGQRVGVVGIGGLGHLGLQFIRALGAEPVAFSQSPNKEQAARELGAVDFINLSNPDDLARAQRSVDVLLVTADAKGQAYDTYLSTIAIGGKLIMVGVPDDKMAFSAFSIVSGGISVIGSMIGGIKETTDMLVLAAAKGVRPVIQKLPMKEANTGIKMVDDGSVRYRVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL75</accession>
    <name>A0A8K1FL75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Drug/Metabolite Transporter (DMT) Superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009891</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRT-like transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL75"/>
    <dbReference type="OrthoDB" id="416555at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013936">
        <property type="entry name" value="CRT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326:SF1">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08627">
        <property type="entry name" value="CRT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41728" checksum="84454861716AA8FC" modified="2022-08-03" version="1">MTEKATDARSSKLVVSFVAMVFVGLGNKIFQKLQTIPMHNYPMFLNLLTTFVYIPISFAYIIPMIKYGTAITAEQRSVPKKTFAVMGGLDSVAGILQVFAATYLGGSLIILLGQAAIPVSMVISSALLQTRYSIYQYVGAVVVTIGLIVVLGPGVDSSAGADSHMTIVWSMVMILSCVPMCLSSVYKEKALGETELDVVYLNGWVAVFQFMMALPLTIPAAMIGNPPVEPKDIMSNLYDGFRCYLGHNTIDHGPHKDDCANATVFVSAYIVFNVAYNLLIILILKFGSANILWLAMTIMVPLGNVAFTFPFMPEHQPLHAKDITGLLVIMSGLFVYRFLEDIAATWSKRVKNKRAADPSTSELKKALILFEDGEPHMESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLA7</accession>
    <name>A0A8K1FLA7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLA7"/>
    <dbReference type="OrthoDB" id="2100988at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="669" mass="76953" checksum="2C10ABFCED69DB10" modified="2022-08-03" version="1">MLVDSRPMMGRAAKMRLYVVAGLSLMLLGWVYHSVQFLHAFGHSHAAETTREQPLIVRTTAAVRKIVDKANQKHDDVEDRATNGETQWREINVKPSVEDWPMKQDFYTAEYPSNETSTTIIFNLFKGTPKAFEMQLDMATRQKHVVPPEIWVMCFDSPMRVRYEAVVRTWKAKKDIKSKIVFTTSDFNHKFHGRFLLAYMAKTKYVLVIDDDKLIDETTVYDYIRLMKKKKGLWGNMGHIRAPTFAEYKSWPRNFTEFNTTKPPFVEYAEVDYLSGMWFLEQSWLEYFVKERPPSFETAEDMHLSHVMRKYLNLNSYGGAVALYVGKAPRKKHAATVGSALRLREYIFDHQLGRGNKVADVDQPIQTLVYAETVDDIEDFRRKVEACSPIKRFLRDVAADPGGVMATPWCDAGKTAVVFRGGKEQDVVGMIAAAERLCAATECEYWSIKPKIKHPIRYFNMREGYGQAETDIPWQTAASDVLMSFVGVLNNILPRYLFIPDVKHARWVESEPSEEPPKMNRLQIYHETIRLAINIHRSSPSNQKWSRRGRADLDNEAYPSTMRAFTWRPSTTDDENAMSLWTVLYSDPSKAEVTTSPQTEDMGGVDKYPYPKYTWSPAGGWWLETKNWRTKTGVALGVMALVALPLALHSSRTHVKYPSPERRKLSRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLK8</accession>
    <name>A0A8K1FLK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005406</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1-&gt;4)-alpha-D-GlcN-(1-&gt;6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLK8"/>
    <dbReference type="OrthoDB" id="1741594at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051751">
        <property type="term" value="F:alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="50118" checksum="359ED0FA850BDFD8" modified="2022-08-03" version="1">MTEGTRYSVVFGGALAIRLVLLAYGAFQDEYLPVKYTDVDYDVYTDAAREVANGNSPFDRTTYRYTPILAYLLLPNIYVHEIFGKLLFVAADLLVGHLLMRILQLRGLTETRALHYVCIWLFHPFSINISTRGNADSIVVLLVILSLLLIMQKKAVLSAIAYGAAVHFKIYPIVYALAFLVLLSGDFNVSNAKWSTSCQSSFCFWVQLAGQLNRDRVVFGLVSGGLFLSLIGIFYHLYGYQFLYEAYLYHFTRTDNRHNFSVYFYDLYLRYNTPSGFGVGLLAFLPQLTTLITISVVYGRDLSFALFALTMVFVIFNKVCTAQYFLWYTVFFPLILPTTKLRFRWEGAALIGAWFASELHWLFWAFHLEMKGQNTFLPLWISGLLFFSVNVGVLSTLMRHHTFTPLFKRGDIVRLEDPNNNKQLPDDTRKIEHDKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMH4</accession>
    <name>A0A8K1FMH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMH4"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="73"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="42825" checksum="94CC4829FB2B293B" modified="2022-08-03" version="1">MGATQSWCFGENTQDAGSFLPGKRRGGRNDSGSSTSSRSSNGMNNGPMHQRSIPKAIQVHAPAYSGGSFETKYEMISEIGHGSTSIVYRCCEKRNGTTHACKIINRRAVLGKRNELMEQFQVEIQVLQSMKHPNIIRIDDVYLTDSKICMVTEYMDGGELFDYIVDKGTLSEVEASSIVRKITSAIAYMHACGVIHRDLKPENLMLTSKHAGAEVKIIDFGLAKLLDNEATTQSFLGTRGYLAPEMLQRQAYSRTVDIWALGVIVYVLLCGCLPFNDDGGRIANEKAARAKFGLRYPRWASGLSDSAKDLLQHLLEVDATKRYTAEQALAHPWVTGQQTPDHYLRSPNYLRNIRAKRTAQANGNRPAEGEDTDEASRIRSRRQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMR0</accession>
    <name>A0A8K1FMR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMR0"/>
    <dbReference type="OrthoDB" id="168085at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="174" mass="18896" checksum="E92E640146D8D5BF" modified="2022-08-03" version="1">MEDRLALRPPHEVGRMSGQSELERDENEDEKVYYGFGVFMGLPLADLRAMKEEFEQAQGAMVHRGGRPSAPGRNTHAPAGMPPQESYGEYEMGRSHGISRGNGADYGRGPPPCDVPGHNPMHQRHFSNPSGAPHHREYDAGGNGNHDGHGSDGSEGSDGSYSAPKLHSLNFILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNG6</accession>
    <name>A0A8K1FNG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Armadillo-type fold</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="TMW67304.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4816" mass="511682" checksum="0CF1D2F9C4A7B3D1" modified="2022-08-03" version="1">[encoded data, 4816 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPT4</accession>
    <name>A0A8K1FPT4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003703</name>
    </gene>
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        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
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            <taxon>Sar</taxon>
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        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
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            <topology evidence="1">Peripheral membrane protein</topology>
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    </comment>
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    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ15</accession>
    <name>A0A8K1FQ15_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011092</name>
    </gene>
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        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429407" evidence="2">
        <location>
            <begin position="21"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
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    </feature>
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            <end position="280"/>
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        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="Phobius"/>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="363" mass="40036" checksum="369B8B69FD883662" modified="2022-08-03" version="1">MRQWRLLQVMLGCFIRSSLGESPALEVQLTAHGELTTPFKPGHIAHTFPSVLSYVQVNSDFVTGFSALDAFSPVSQDALDASSLLRLRIQFVTEETDAVVLSTRAHLAFRAPNASSETLKAHFPSQATRPASQALIATVQIQNLTSQLPSPGSYDVFLHLESPLIQTPLQLLLGAVEVPNSSAHDGSIAKREGFSLSDLWTGSFINKFFRRCAVDAAFVSTLEDRLVWSELLIAVFSVTYGAAIYWLGPFDFALGQQRCYLISCIASVLFQVVFLAWSIQRCPIHIAFPLALVCGGVYLAAFNLTNILILIEQLPLRRYQDADHQYELRIRSSRQTIDGIPSPSALQGTTRVVMIGYKKARFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSV7</accession>
    <name>A0A8K1FSV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peroxisome membrane anchor protein Pex14p N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSV7"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="329" mass="35086" checksum="A7DB6882D9736E4E" modified="2022-08-03" version="1">MAIRDELVAQGVRFLQHPKVQNTPLSERLSFLEKKGLTPQEIAQALKRNDEENAARAAKAIESVTSAKAGERLKGRVGIVVGGNTGLGQFIAVRLATEGAELTIIDAKQGKGVKSVVEQINSLPGADASSTKLLEGDLHSWAFIDSSYSSVIKEHGRIDFVVNCVPSGFADGKQKLLTEIEEKEWDDALGVSAKAVFLSCKRAVQQMLTQDNTAIRGRIVNISSVYGGMVARKGHFTFGVSKSVVVQLTRQIAAEFAGKGIVCNAVAPGHIDDSIDKRDCVAPADANRVPAEEAGKALDVANAVVFLTSDDTRYIHGTNLLVDGGFMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C269</accession>
    <name>A0A8K1C269_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C269"/>
    <dbReference type="OrthoDB" id="332250at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010564">
        <property type="term" value="P:regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039893">
        <property type="entry name" value="CEP120-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="516"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="731"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="785"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1083" mass="123968" checksum="2C149FAC6DAE0EC5" modified="2022-08-03" version="1">MEESHEYGEEEFEDAGEEKEAETREAEAESYREEYEEEEETDTPAVEAPSPLQTMRFEDDDEEPSTASTPIRANKAVKKKKKTVKSVLDQSPWTYTVKAKRIRELRIPAANVWSGGADAPVKTPRGATLLPVIRDLRIFSVLDKQPMQSHGSKWKSEPRQDPPKPPNALSRSSISSATSPGRRSGVVQEAYWKNTHGELQWMFTMDRFRRLKAYSPRIKLFVYGIGVNAQADNVGALSEDSPRDHRKSIVSLGWFFLDLRTPDLPERWFKLQNSPFGGEIVVSTTFLPADMGHARQSHASQVVSNVEIPLKSLLKQQLFTSDATEEAVIDGNFSFGQPSTGGTVTARFSVELIKQVDEKHVEEEEKAVVASPDRPEMDSDLRDLAPLVVHVQHNKTEEALEEILVPNVTRKYRVFVQIKSLRNFESTNPVSISFVNPFSGKERIETPLLSLAKKAEVVVPDAHCIFDIYKDESSLRDTMEAPMILDVNETLSDGFRRLIGQAVFSVNYLYFSEETFCCADPNCGTVFKSDDDAHVHWRNTHRDSEASSSVAQIHSYKSCSIYLPVMSSDTPVNSSAPTRIGAVRLIASLEDMGILSSEEAAITQEMRVPRHMGRAPRRVHFQGGSTRVVESFDDDQSRNAIRPAVEVAMDDAVQDGSGNANVVSEPVDDSAAQREIQALKAQLLKERAAWQQEQVSQQTQWKKRLSDLEKARMDELEEEWARREEERSTVVRAAQTEYQQLEQKLRATLAEVDNRERNLAIAEAALERDQRMQREDHELLRKRLQSEQSHALQLAQRQVETLEKRVAELQSHLQIAEKRTQQIEEDFADYRRQQRKVPEAKLREEISSLKGHIVELERANLVETRAREEAEANVDKMREQLEKMAKLVQNEKKRNETRVLEELEKLRLKYVAREERYVLDGDREELRAIKKQLDELRQVNRVGRSRYDDTGSVYSVSRPHARVHIPQASPIHPRNHGDVLYEAEEIYEDTPATTELYDQDIIRAPTRKPRHPGPRLAARREMAVKENAQANDLPRDRELQRLQREKDLLLRTGTYDDNSFLVRELDRLIVLRQDQLTRQQRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H8</accession>
    <name>A0A8K1C2H8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2H8"/>
    <dbReference type="OrthoDB" id="173920at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="59861" checksum="AC40BB377447BD9F" modified="2022-08-03" version="1">MPTSHQWLAAHLSPKNLAFWRYMLVERFDFTVDEGKAFNVDGGDQTYLVYPEDPQTLEAVAQWEKHHVEDAYENFLDEDLKLWTHLGVYFRPSQHGFLSRIKAGEASMEDWPDQEDPYTLFCDLELLTDKFGPSQDKLHTYGVDKPKVSPCLLSRMTTPRSHRGYELLEHCGINPQYWEINARPVSMMQISQTWIVCSFLLMLPKGDTVMQQALEKTPAIASSTLLDAFTAESAIFQTVLSFVPVDTPSEAIQTLANISLALPSSHQWLAAQVNPSNRSFWQFMLFKHFDFTVVDDKTLNVDGNDQAYREDITDPKVLRAVAKWEITHGADAEAFEFLDEDFEWWKGCGVYFRPSQYGFLGEIQSGEASMDEWPEDEDPFTLFCDLALLADRFSPFQDTLQTFSDGWGSIYPCLLSRMAKPRGLGRGFRLLKHCGINPHYWALIPTPVRRWAKFGGGPGGMYRTSGVLPYGTIEDTEEELQELVLASVSDWRCVKVNLDEYCGTVFYVGPSNPSGRWIGFIGKCTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3C4</accession>
    <name>A0A8K1C3C4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polycystin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polycystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3C4"/>
    <dbReference type="OrthoDB" id="444119at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046791">
        <property type="entry name" value="Polycystin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF183">
        <property type="entry name" value="AT14535P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20519">
        <property type="entry name" value="Polycystin_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Polycystin" evidence="6">
        <location>
            <begin position="123"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="36702" checksum="8A390E6B47A9EB92" modified="2022-08-03" version="1">MQLGEDSDLLPAARSTPLLTADEILELARHDATVCLQRWWKRRRHHNHQRIAELREQLCRYATSLIEKRRQSRIRAKIRDIVIHLVFLYVYTVSTHHGYTGEQLFRLIQAVRTSYSRESAQRFSDISSQADLFTWLNGPFLEATYVSPPPLLSRVGGVRIGQLRVTRSNCSSRAASFFPTALNVSSGADFYCYGADSGAFDTENENTAAFGGTTGSSFPFLGLNDTNADTEREEYFSSMQTPTNTDQSYPAPAYSVVLPRSDVSQAREVLSWLRHDAYVDAYTRTVMIDVNLYSIMLRHALAVRFLVEFLPPSGDGAVTSQSTPCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3S2</accession>
    <name>A0A8K1C3S2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Membrane-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3S2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482803" description="Membrane-associated protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36862" checksum="86C1173255EB587F" modified="2022-08-03" version="1">MRTLDRWIAWCSLWLLASRGVVWAANATNTTDALASSSPPLLRFQPTPSIAVTGEAVQGRSLAIGLGILLVLLVLACVVHSIHVYCRRRRMDETEDASPVVDVYPDETNRSASVYHEPVAWSHTRQKSAPRCSPFATSIANIKASPAQHHDRKRHRSSSDLHFTLLQTPSTTRGQRSVHAGRTSEQLTTTTTSTAKSLRKNRQPNSETDQSLQRVTLTLRFSDEVPVMEGSDASGSPLALLEATSPSGSDASFVLLSPSMLENLREAQTSRLPAAQAWIARELTRPSSEDSGDTIVDESRPYLRTNSSLCDFRRDVHYEDDPLCITRNSEEVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C421</accession>
    <name>A0A8K1C421_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008606</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C421"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019788">
        <property type="term" value="F:NEDD8 transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="69"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="24451" checksum="47D9AB610B0CB33E" modified="2022-08-03" version="1">MIRLKAKQQEKKAEEEKAAAAAAAAETTATTETADANGAPAEDKPKTVKILGVGRGKRGGATKEKKRTPGEIRIQKDIAELDGGQAATVSFPDANDLTVFNVKVCADTGLWKGATYDFSFRIPPMYPHEPPKVKCLTKIYHPNIDLDGNVCLNILREDWKPVLDINSVIYGLIYLFYEPNPDDPLNREAAELFRNDPSQFANLVKRSLLGYSVSGVEFDRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y4</accession>
    <name>A0A8K1C4Y4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y4"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF16">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="155" mass="18245" checksum="9FCE0F461F5EA766" modified="2022-08-03" version="1">MKYRRREAPSDVMVVDEYAEGTLVKQGGRIKTWHKRFFVFHKGFLSYRKDARDTTKVLRKELVLNIAFAEKEKEIPFGLCITLKSGRALMVSAKNDEEAHTWYEVISDFLAQQQLCKEMNDMEIQERSVYPSFSSEVSTTRSVDSDDEWWNENFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5I8</accession>
    <name>A0A8K1C5I8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial splicing suppressor 51-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5I8"/>
    <dbReference type="OrthoDB" id="5282002at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF1">
        <property type="entry name" value="PROTEIN MSS51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="2">
        <location>
            <begin position="96"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="51220" checksum="6A2E6DC6BF57F8AC" modified="2022-08-03" version="1">MTRTKRASRRADGATSDKTTTKDLQLDPRGDGMYSGTFRWLETKKFAQLPAFPSLGSQVCLTSGWEGFLRSRSSRTTNLVEIATQDPSCLDALSFPITFAHVATLLSLMDARTQEKHVVVLGATRKAEQRVWAITDYWLELAHLFSETQLTLWFIGPEVDSQCPTKPMPRNLRVQHIQGKFLEFRNNPASNVLTPSNTVLIGYNTGFGNFVESERHELLFSWLPDLYDIADSGFPAIFTCANDYADMKGEFAVQSRVVGAKMLLLPQQNPFSAASHLHEEGKRETAWSRGNSFLYAIQGVDSSRRVRIASRDVKKLQDRLDEELDLHLIDTLGRHFYKGMVLTKEQASRCKALNGSSTTSSTTKPKTAVSTNASAESQLQTPPFQILPGQGPKDNVILVHVPEVKSAQERIAVDVADTALTVYVPDKYLLRTKLPFAVENNGSVQVALSTPFLQIHVTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5V0</accession>
    <name>A0A8K1C5V0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-rRNA-processing protein TSR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5V0"/>
    <dbReference type="OrthoDB" id="263560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23577" checksum="FD0CD0845366927C" modified="2022-08-03" version="1">MSDNILLSIARDQAAAFQSDAIKNPWDYFEYSVKLVLARWTALRMAMEGQWGGGDVRRKYEILLEEILNIYKYHKNVYADDMVTNISEYVESEFGLVCEDGSIEEICDLMALLADECKKGQYDRVKALHEQVQSLIPIDLKKAKIRQEDGLGASMGEAQQGGAMEDGGEAMQEEENLVDEDGFTTVRRSSRRKAAPRFYDPSAQFPGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6L1</accession>
    <name>A0A8K1C6L1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003474</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6L1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="3"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="42957" checksum="EEE8451E4676B598" modified="2022-08-03" version="1">MARIVIIGAGYAGWSVAKTLASSLRSSDATEVVLLEKSKFFYHAVGAPRAYVDAEYAAKMFIPYDNAIPQTEFVRRVRAVATGISASKKEVMYQVIGDDDQPATETKTMTFDFLVLAMGSSHTAPIKEAPANFSPEHTKQQLKQIRSQLVEAESILIVGGGGVGCEVAGEVATYFPNKKVTLLHSHERLCSSNGLTDKFHEYLMHSLEKLKVNVILGERLIERLTDNSFGRRTLMTHMGTAIESDVQLLCSGFNPLSELMRAMDESLVDDNGRVRVNASLQLDASKYPHIFALGDLNNHPAPKSAGSAYRQGEFVAKELMAFIRNKQHEVTRVFPCPSTQSITLSLGPNGGVSQLPVFGGIVFGDLLTRWVKSRDLHVGVIRWVFRAPANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C745</accession>
    <name>A0A8K1C745_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C745"/>
    <dbReference type="OrthoDB" id="549039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35287" checksum="10524820F602BF0E" modified="2022-08-03" version="1">MHYAAAHGRLDRVKWLHANTTEQCRYDTMAVAARNGHGDVVRWLQHNRPESHKSMTHRIMDFAASRGFLEVVQVLHEERKEGCTTIAMDGAAGIGHLQVVQYLHAHRKEGCTPAAFDTAAANGHLAVVEWLHEYRSESGTKAASFGAAVNGHVEVVRFLLNHRDSGYVDEGIRLAIPNLLVKGDSVVLPLLLTDCPELFPLFSMAMAAENGHLDVIKLLHPTRPREDIEEALVRGAKNYPAIVDYLLENDKFSTPVLKSAVDRARTLAVSVKLHQHILPEANTVNVFGLAPSPKPCSRARRKAKKPMLLARRQQFACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7C6</accession>
    <name>A0A8K1C7C6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000134">
        <property type="protein sequence ID" value="TMW57650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7C6"/>
    <dbReference type="OrthoDB" id="158706at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter family G" evidence="11">
        <location>
            <begin position="102"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="10">
        <location>
            <begin position="223"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42777" checksum="917CEB013C418B71" modified="2022-08-03" version="1">MSAMISLPRSVTRGMIKQRVQGVIDEMGLRVCEHTLIGDLFRKGISGGQKRRLSIAIELLSNPSILLLDEPTSGLDSSSTYNVMKFIVKLCEEGKTVICTIHQPSSLVYEMFTNVAILSGGRTVYFGPRSESLKHFASAGYECPMYANPAEYYIELVNADFEGHADIAQLVSAYSVSSVATNMTAMIAADRTNKDTDEHHYSRPSRHPPDNSGYSCTATPSTTYENPGIYWVRVFMYFMLSFMVGTMYLSTNDDITEQDIVPLLFYVQAFLVFMSVAVLPFFIEQRSVFMRERANSGMSVFSYVLANFIASLPGIFLIALISSVLVVFLADLNSFGWFLLNLFLSLVVAESMMHVIGAAVPHYIIGIALGVPEADRCPGWKDGTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T5</accession>
    <name>A0A8K1C7T5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T5"/>
    <dbReference type="OrthoDB" id="167334at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="644" mass="73561" checksum="CBF27A95ED72A8A3" modified="2022-08-03" version="1">MWTRWHARRGALGPATRLTAISAPQRAFWKEASGLIDRFRASPTVEATQDATSGPTESSASTVSTPKPVASHDPPHAALQDLFKTIRRSTNAKRLMVIWNAMAKHQPFVVEKGMVRVVDNATQPNDRVLLQMVPVPEMLQLARSGERAFVVERAPAFRPKRALKAAESSEDNNHEEPSVETPDLLKPGSNSLLLSETLVAHKLFVALERLGEHKTLVQFFETLEQERRQFRTLELLQTRDETDRALVTELAALSGYAESKYIASLNELNATSKIVKRCEPHLSELKRYMFDRDTFRSMLRACAIERHGALARALIDQAMDRFPLQTFNVRQYTSAIHASLRAKPKTFARLEDALHVYRRMRHDAGYVLAPSDWSMLFNSCVYLDNHDAAMEVFTSYREHGIAPFQTRFEQALRTTCRFKRYETVLAMVEAWLRIESEQSEESPGGEVECFNKILWEMLKGKPTLEQVEQVLRLMERRHATTGAIVLRRIITHFLQSHEEPDAAITRFLSLWETCPNVIQRNKFVLYLILEQCETNHWNAQSERVIAYSLDQGLEMPLESAVKVMESFASRGELDKTIELGESILASEQPRAIPDKFFESLLKSYHFRQRFDDVVRVAETQTLSSRYQKSPTLAAIVRDAESMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C984</accession>
    <name>A0A8K1C984_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C984"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="81545" checksum="39E1400CDE3B1EFE" modified="2022-08-03" version="1">MIRLLSKLLAHDAALRVVAIRYWTRPNGHLYDLRIDLQHAVSGDRPQEDRDDHDDHDDGATDQHQTHTRAPGWFRDQDSELVVLHEGECITRVHEFYASDESLVGLELETNLARVVPMGTCMGTKVLGDVVQDAHVVAIKLKRRGDALKLMSKATITNKIRRSQVVFRSLPTIDKLKGRYAKLQAAARAKGAFTTTASRLDEQVKTFVAMVGDTIKDLAGLSARGIVSVGCLVASLLSIMRRAKREVAPLLGGMLTKVDERRSMLEAITADLMDLRAVVVRYNKAEIKACVKTSSLIRHVMQTVTASNCEALVTLQAAHPRESFDCAHPHDSFKFSITDNLLAYFANIGNVDRFAHVATVHARAYHSTLGEAVTDLVLRMPVVQLAIAKGNVDLLVWIISHTGLDPSDLPPLPLGALAAYVAVDELELDAPVPELIRQNRMNQEAVQLVVDQLQRRREFARRAIDLFKRNGLISMDELTALVKDITVVWHLPLIYMLGKVHLSRDDLKQLFSMAVEHTVETKLVVSEEAYSYFKELLEQAKAQSMLTKHEYDVITLRAEIIQAKIRAEDANAATNTLRIQLREIREQELPSIRKELASVRRAVIGLQAQNVCQDRRDRQLAFVSAILSAAGIPGLDLLGKCLDMCDPMNLLCSMVPVDAENERTFVQDPTYELVVRNDVKNALASRFGVEAELLAKVLRRLGAPVAYTQKLNLASAVRRVMANERRCRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Y1</accession>
    <name>A0A8K1C9Y1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Y1"/>
    <dbReference type="OrthoDB" id="165482at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51183" checksum="7234227BF7B0015E" modified="2022-08-03" version="1">MTIPRLNHHEVFYEVLAQPAKSSETGASTELLTDEEPALATLPVESLVDLELDGEELLDWSNWTTDQSDASSVVSVASPTESSKSQPQETKQTALARRRERNREAMRRTRLLEKETLTSLRMTVQRLEAQFSRLTTASTKSSSTELVPADPESSRREQLQHRILDLVSLRRTLENENAAVKAAIQEKAVLSSVVQKILAENPLDEAVNEKLALLGNPTSASSPSSSSPAPATTQFHPLSPPAAKELMTEFCTEMERVKALPWPSDVDTIEIFGWKTRRYVDSTTNEMHFELVKSFSHIDTDTLLDRMWANAMDVSSAPSTHRDMKFLRLDFLQHVSEDAHVFIRDIAHPVDAIIFRAQYMVFRVRTSSGYIFAMQTITPTEPRTFDEETGSKIVWIDLSCGLELVRTPSGGCMLHWRGSTNYKSAQHAAENAVKILVSALRWESVLNGGGHWMLTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAG9</accession>
    <name>A0A8K1CAG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAG9"/>
    <dbReference type="OrthoDB" id="187748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32328" checksum="22D1164545880525" modified="2022-08-03" version="1">MTATKKVFLVTGGNSGLGYQASLDLAKMENTHVIVTGRSAERVQAAVDKIKAEAASSSVVEGEVLDLGSLKAIQEYVTKFKGRGLTIDALMCNGGVQIMTKTPTVDGYESTFAINHLGHFYLTTLLRDVTRRVVIISSETHDPAEMATTPSPNVSDLEQLAHGYEKYEGNEAYTTSKLCNLLFMKEFVRRYPNGPEFIAYTPGFTPDTALLRNTGMDVAMIVKICEQNNIPISSTVVSGGVMARLCADDWAANGWTTDMYIRVSVPYEPSVQAKDPALARSLWEKSEELIARVIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAP4</accession>
    <name>A0A8K1CAP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C-factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007119</name>
        <name evidence="5" type="ORF">Poli38472_007122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAP4"/>
    <dbReference type="OrthoDB" id="68267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24620" checksum="047673332F7CFFBA" modified="2022-08-03" version="1">MTKTVLITGSSRGIGLALAERFHADGWNVIGSARSPATADKLKALNLYKVVQLDTTDEASVQSAAKELEGEAIDVLINNAGMSHMQQDFDTLTKDALLEHYLVNAVGPFFVSRAFTQQLKAAVAKNGSAKLIQISTALASVALNDGGVGYPAYRASKAALNMLHSSITHQLKGDKIICVAMCPGYVATELTGYAPYTIQPSESASAISKVIEGLSADDKGKFFNNQGEVLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBK2</accession>
    <name>A0A8K1CBK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Selenide, water dikinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBK2"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000025">
        <property type="entry name" value="Selenide, water dikinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000010">
        <property type="entry name" value="Selenide, water dikinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PurM-like N-terminal" evidence="6">
        <location>
            <begin position="84"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="7">
        <location>
            <begin position="210"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="43339" checksum="8C80C9412F67CB7A" modified="2022-08-03" version="1">MEEAATKTNEIIQREFAEQSATPAKSRAWLTAYYDPEVHGLDKDFVLTNFSALKGCGCKLPQEKLLGYLEDLANDLKPNETPGMDSSVVKISHGKDLYLVSTTDFFFPSVEDPYIQGRIACANVLSDVYAMGVTEVDTMLMMLGVCRDMNDKERDVVTTQLIRGFNDLAREANTNVTGGQTVMNPWPLVGGAAMSVRSESEIIRPVNAVPGDVIILTKPLGTQVAVNFFQWRKKPERWQRVEHIATEEDAAEAFLTATESMTRLNLNAARLMHKYGAHSATDVTGFGILRHARNQAKSQHQAVDFEIHTLPVIRNMVKVNDTIGNSFKLLEGLAAETSGGLLLCLPEANAEAFIKELRELDGKPAWVVGRVVPGSNDARIVPDFKVIEVSPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC15</accession>
    <name>A0A8K1CC15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Purple acid phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC15"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778:SF7">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="10">
        <location>
            <begin position="162"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="8">
        <location>
            <begin position="282"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="9">
        <location>
            <begin position="519"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="585" mass="65785" checksum="F6370EF7A3A2AE34" modified="2022-08-03" version="1">MKDDGYVRMDVEGSALRPRRRRGPGRRSLALLAAALVLFTIGFVVVSPSLEQAPAEDGIHLTTWPKVIEDGGDLVVFWPETARVNKNDYLTLSCGPQQGTDDYLARKNVTEFDATLNSVRFSELFMMRCDYSVEYFRYHKGKKSYESLTKIQVGMRESFNTPKHGHLALTTQENAMAVMYNSASSRTPEARYGTDPTNLDHHATGTSTTYKASDMCQAPATTVAQRLFRDPGFMHTAIMTDLTPETTYFYQYGNDVDGWSKVAQFRSRPKKDTKTTKFIAYADMGVDTAPAAQSNAVRVYSDVVGDGFDSFLLHFGDISYARGEGSVWDKFFHIIEPYATRVPYMVSVGNHEHDYTAGGEHDPSGEAGSAGNGFHPHWGNYGEDSLGECSVPMYHRWHVPATGNSLFWYSFDYGGIHVVQMSSEHNFTRGSNQYEWLERDLASVNRIESPWIVLTAHRMMYSTQKDIDVDIHLGERFRAEVEPLLMKYRVNLVLVGHQHSYERSCPVYQGECVRDGKSAPVHFVVGSAGFGLSDNGFTSKYGNWSLVHADEYGHLRVATTATQMHIEFISNRNGIVYDEVTLEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCC1</accession>
    <name>A0A8K1CCC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aladin seven-bladed propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCC1"/>
    <dbReference type="OrthoDB" id="411991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045139">
        <property type="entry name" value="Aladin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057403">
        <property type="entry name" value="Beta-prop_Aladin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14494:SF0">
        <property type="entry name" value="ALADIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14494">
        <property type="entry name" value="ALADIN/ADRACALIN/AAAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25460">
        <property type="entry name" value="Beta-prop_Aladin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aladin seven-bladed propeller" evidence="1">
        <location>
            <begin position="142"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="52293" checksum="C0C6646D5751289D" modified="2022-08-03" version="1">MTWIVPNQDSVTLGELQGELYSVSPRDEFHIGDAFVRRGGTVFAPVRVTGLKQRRPFGQQESLTEQDLNDEDWDRQAPGALQLLKRTAKALQVFFVEDERKVARSLLESAAWFITSTFVRPVDGERDDTSAFVPANNKKQLEESISAIAWHTSLTVLAVAQRDGVVSLYDAVAGEWDTRVLAHRSQQDITSLEWSHYSGGVLAVACRGGIFLWKVPSKRQEPELLDIVTHPTKRSFQQVAWNEDGSLLAAFADKTDSVFIIDVIMNRRSELKCRQQVTAVHWSPTGAYLFVSTASGVSVMWETCTWQKETWDVAASSCAWSSNGRCLLVAHRNTSLIYPYEFPATPPLINVGINTPPIDFAEKQLFSLDKSTFEYVGGAIKSLTWDPSGTRVAVTYTPSTSSNGDVGSLVAIFSVAWTPFLIFTMSGLIRGPPKSGVPRSVTFASKFDEGALLSIAWSSGLISFHPFYFEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCG8</accession>
    <name>A0A8K1CCG8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCG8"/>
    <dbReference type="OrthoDB" id="77046at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357">
        <property type="entry name" value="COP1-INTERACTIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="351"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="735" mass="82254" checksum="2A20074EA7984E61" modified="2022-08-03" version="1">MEAEIARLKSECHAKDETLNQLKLKTKSFVDNLRNELAGEKKKVAELVEQLKTASGGGNGAHSDEEVAALKKEIATVTQHENELKARAKTFADSMKAQLQTEKDKVHKLEKELEEKMAALASAATNAASSDLLGFGDTSNKDAEIEELKIKLQGVEQETSGLRDQLRQAEERAKQASQDARQAQDALQSHQTSSDAQIAQLQAELRQIQSHEKDLESSKGSTEAAFGQEHSQLESTMRQNQTLSDQIQQYKIENEHLQKQVADKDFQLELLDSYRRRAEEAEDQGNALRAQASELQMRVSAQQEESAKACAQSVDLERQLSEMTSLYERVNMGRSQSDLQLAEAQTTIKSLEGARDRVDDVNKQNMQLNEKIFQKESEVNALKEDVKRLTSQVKELNDRLDTSKSDSFNRKQQSESLEVAKKQAEDAAKDLLAKAAALEKRNHELTASVEAVTKDSNEKRQKAKVLVIALTNEKQSLVDAKSELQKEVDRLRMELNQKNVENERRLKQVQEENQQRISQSTANIQNLNDEISTLKQTLLVIQESERNQQRAKELANAKREVEDANKKRLAAKSETQKLAVELENVQKCLHQLADNATSSCTSSVKKLNNAQERVNEALAVLEKRASASGKKPQPSSPRGGYRTVEVEDLRGPEAVKPISPTSGARKVEDNLTRLTDKLNAMLEVTDKLCDLSIEQNDVNLKDVVIDKVTQLFTQCFSEKLRAAYAKVDDGESTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCP7</accession>
    <name>A0A8K1CCP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCP7"/>
    <dbReference type="OrthoDB" id="148713at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="41983" checksum="77C6FB22DBFD1648" modified="2022-08-03" version="1">MTTFTPKLFTHITLGGKKDPIQLQHRLAMAPLTRLRAGDSGVQPDYAATYYRQRSTPGGLIIAEATNITPTARGFLGSPGIFNQDQIDAWKPITKAVHDEGGVIFLQLWHTGRFSHPSLQPGNVLPVSSSTNLPLDENRTVPTMDGRLPLVTPRALEASEIPLIAQDYRKAAENAIAAGFDGVEIHAANGFLLEQFLFDGPNTRTDQYGGSVENRARFLFEVIEEILKSIDSSKLAVRVSPYNKPCTQRDSNPEATYKYVFEKLNDYDLAYAHIVEPRGFHYENEWAPKEGSTAFFRPFYKGVFVTASGYERDSAMGVVESGVADIVAIGRNFISNPDLVKRFKLNTPLNAYVRDTFYGPDEKGYTDYPFLSEAESTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ6</accession>
    <name>A0A8K1CCQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ6"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15431">
        <property type="entry name" value="FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15431:SF4">
        <property type="entry name" value="PROTEIN TONNEAU 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48310" checksum="7F87F95D61D45CF8" modified="2022-08-03" version="1">MHATDEELALKEQVAKTLETQGVLAKIKAELRAAVFQAIHVSNKDNDRSRSLGKCNPDNEDDDAIAGYGDDGSVALELVCNLLECLEMEHTLSVFHAEARLDTRKREWQAPSKLCEYMSVSYEKEETPILVQAIRQWRKGEPRRNEEEARSAPSAWAYKEPMKVDVVREVVTSRQEELPPLPRVSAPVVTTEEEDGELEASLAEEIASGSFEEESFVDEASTSHDNGATVNFSVAATRKINTHEEEEENEDEDEDEEPVVASPPPVPTKLGALPSLPGMTAVTEKSVVNQEEEGDDEGEEEEEAFDEEAEAERLHSLDAKLRAMEAEDDTGILQQLKASLQVDLQPDNDEEAEKGSTKHDEEEEGYDDNYGSDFEEEVEEEVQSEVSEDMASISALSESEDIHPKATTAALANDMAVESEDALNSYDYIEPVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCR2</accession>
    <name>A0A8K1CCR2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW60984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCR2"/>
    <dbReference type="OrthoDB" id="164034at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="475" mass="52679" checksum="744E03E93F4D0810" modified="2022-08-03" version="1">MKKLETTLVPERRAPLLRSLSARSLDQMEDALRAVQNARPRPEIILRWKRFGLLVVLSSVALAGLAITLHFGIPLMSVDPYDAESKVDLLNTYSGVIMGFLESVVGLLLGYLFPVFTVYLHNLKWYPNDDPANKPIGKLKKTALLLFFPIVMIAVGSSLSAVQTNQEIPDAVKLMRRTRRLTESDGLMERERGVLDAGLRDTVSTCDVGELRMLPRIATATRIATGFPTYEWSDELVAFVSSLQGDSSLTMSYSDRANGELRSQAESILTVQTTRDLLVQGASMIQLMAQESGIVYSTDRGDPSDIFDVMASVFRPLDGIDVENLTATFSRTVASDETPLSWETITVDIPVSAPATAAVAWQRHLALLPNHEWEVYVSNTGFGSASSWIACGILVVLSALVLLVPNARARLMPPKGGNARAERFIAVQTEEVYPNLIYKKRFRIGKTGEKIKFREFSVESVGLHHRMEEDEQIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFB9</accession>
    <name>A0A8K1CFB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFB9"/>
    <dbReference type="OrthoDB" id="165528at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="47682" checksum="B98F1E8205C1F9E9" modified="2022-08-03" version="1">MGEGEDPECRPAYEPTNEENLPSTMKYMRSLSLLAVAVAVATSMTGVQAEAMSAVAGLPEQHALADLPVNSGMRNLRSMADGSGPGPSPTPTTQTPEPTTDTPKPTTQTPKPTTQTPEPTTETPKPSSETPEPSSESPKPTDGPTPTPSPSDESEAGSGSTSKTPKPTSKKPATTHTPAPVGFSSTGSNTNGGLDAATTSSLQGSTESADVSSNKRNSGSSSGSKTGANTESTGDKMSTGAVIGIVVGIVVGVALLAFGAVMAVRRRNGDDEDPLSPFELSMDKGHNGAPYANNNNNNSNNNGAAYAGGAATYGGARNNNNAASRDVPMTTDTPAASVDAAGVSYTQFYDPVTSPDSMYAQNPNPHQRIPSGSSDENNLAGSNLWLSAMEPKEQENDVEGERETTFEDALNDDASSSGRNSYDMIPNPSIDIDQSSVISGGSDLDKDFPEFEDQSSRGSYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFS9</accession>
    <name>A0A8K1CFS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFS9"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296">
        <property type="entry name" value="TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296:SF1">
        <property type="entry name" value="TRANSDUCIN_WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="9"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="38922" checksum="07FB9FB38242CC84" modified="2022-08-03" version="1">MATTPVLTFRGHRGAVNALLSDEDKQPHVLVSGSEDGSCRLWDVRTTRATKCINVKKALGLSPQDDPDDASVNSMAFGTAKNDSSPHYLYLAAGSKILTFDLRHEGLILDVAAQELFQDSDEELNHLAVHPGKQGKYLSAPDDNGDIRIYDLEAHRLFKTLRGQHSNICMCAPFRPNAPWDLVSGGMDGLLLFWDFSRGRLKFQIDLNASGQSLEDVNASTSGVNQMFNPPLVHSVAFTGNGKSFAAGLGDATVAVVDFNSKQIVRRLRNHHAAVSQVHFPVFKRDEWLVSAGNDAQITVWDYAAAVSREGSDEEGAYVVKAFQVLDKPNAITSSQHQNLLHVADLSHVISAYPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFW6</accession>
    <name>A0A8K1CFW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFW6"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="73"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="48174" checksum="34489D9744FB4463" modified="2022-08-03" version="1">MQPLVTPAPDVAAANQDKTVALVGTCSAMLSVALALRTLSVCWLQRKALERRQRGQLRICGLPVKTVQHAVDVSVFIVLWYGISIGMTLFNKWFLRVWADGGYPFATTMTCINMFTKCLLSRVVNRCSGTKMTELPRAIYWRLAVPIGICTSLDIMLSNLSFFYITVTFYTIVKSGGNVWNLLFSICLGHQRPSYALFTVILLISSGIALASYGSTQFVLHGFLLVLSASIIGTLRWVLTQSLLKEMDESSNRILGVVYYISPASAVGLLPIALFSEGREILQSKFLLDSQLLIQSMIFIFVSGCLAFALIFVEILLVKKTSALSLGIAGSFKDVTQVLLAVLIFGDHLSPINAVGLIVATCGMLFYTFLKHSEADTTRYALVSTNPDSPDKEFQDTPLPVVIQMRELSPSSSSKTGSTDGSELIRRESKDYDDLEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFY3</accession>
    <name>A0A8K1CFY3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 157</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFY3"/>
    <dbReference type="OrthoDB" id="193329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="53113" checksum="161CAE11EBA47F70" modified="2022-08-03" version="1">MTNRPKPIKSPSRKLGSSDESANKFRNKIMGLSINGDPSSSTAHAGEREETSGESQEHKEYVAQLEQELSRRQESYVRRERQYKVRIQELEAQLNETRVKTAKEGSLDSTMDNLRQMHRSIMESVDHVQDRTSKILQEQEKDLLRAFRARLYSVQEELESEKNKTDDGASAWIQKSKQLETEVEWTKELADRLDRLNQSLTRENQRLKTQFTTQENDREFLVKQLVTVKKDNVRLRSEYESVKQQLEELKDERERQSTPPQYQLSSPVSSTLLSASTSALPKVSYRDGSSRVSTPNIRPNTAVGGASMVLPEADNRYKEIIKRLKRVLDVERRNLQQVRASYKQELQQRTELEMVLKECIQDVRGEIALASTPTTSMPSIHSSPSSRGHITGTLVEARLNAVERQRLIEKLLAKERLLTLLTTKAFPVRSSKGGNDPLLTGEAISPEEIARIYSEVASLTGTSTGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG52</accession>
    <name>A0A8K1CG52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG52"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60054" checksum="BAB268015B335E29" modified="2022-08-03" version="1">MVLQALLENSRVAVDCAQMAVGVLLVPLTYVVIQQLYVALKGEKGQEKGAKLYRPPTTLPVLGNTLDFARRVAKFHHWMTEVCKDAQGTPVLLRTLGQPPMVIISTPEAVEDVSKTQFDAFPKGQQQREILGSVLGEGIIAVDGAKWVHQRKIAARLFTTRALRDSMSATMRKYTAVLLRILERAQRSGESFDLFKLLNRFTIEAFAEIGFGIQMNCLEAEDEHPFQSAFDSIQRAVSLRFMLPPWLTKLQQILGVGPEGQFKKDLKVIDDTVYEIVSGSIKRRQNNEQTRDTADLVSLFLDHFDKYSGDGKKEYDAKYLRDMVVTFLIAGRDTTAQALSWFFLSISREPRVAKKIREEIKVILPELLEGKIETPTMEQVQQLTYLEAALKETLRLYPSVPVTPKSAEQDAVLSNGTFIRKGTRIGIPTYAMGRMPYVWGPDAEEFKPQRWIDPETGKIIQVSPFKFFSFNAGPRTCLGMNLALLEMKIVVASVLSRFDLSVLNEKDITYDFSVTLPMQGELRVNAVEVPRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGI0</accession>
    <name>A0A8K1CGI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGI0"/>
    <dbReference type="OrthoDB" id="166827at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="48173" checksum="D3E3A9F48C810F86" modified="2022-08-03" version="1">MVDTWLHFGEELIWTMEGFAGGFFLPAQRSVHCRGGFFASTTQTDALAMQELDQIKDEFQLKQQRQQSAPTLAFPRESHPPPNRPSNQPSKTSITIPQEKLTLTQPTETSNQPPPASEAPRNLQSPRQRLQVAEMVMRKLYKKNLQSEQEVATLKAENAKLMQRLAELEKTLSLQPTTLALPAQVPTNQPIATSIPFLAHSVLANPPKMETINHIDEQQLDCLRHLAAEQDKTITALKIRIEELSTQLLETKDTRAAGPNGKRTPRQVVNRLQSRLQDALTESERQKSNYLKMKRDFQQLLTLKTKTLYENPAQLNSSAKELVQLMEKQMKLLEQEHSQYLSVYHSKLYEVEQQNCESYAQKRMMEEEIARIAQDVQQRDAVDEQIEKCMVNVFERLRQVEAENLQLKTHVLPTSSVPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGK6</accession>
    <name>A0A8K1CGK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00053">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051171">
        <property type="entry name" value="CaCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878:SF65">
        <property type="entry name" value="NA_CA-EXCHANGE PROTEIN, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878">
        <property type="entry name" value="SODIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434084" description="EGF-like domain-containing protein" evidence="8">
        <location>
            <begin position="25"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2201"/>
            <end position="2225"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="2018"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2248"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="2050"/>
            <end position="2059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2271" mass="243169" checksum="7219E28C914A2490" modified="2022-08-03" version="1">MSPFASVLVLALLLLFLGRHAVDASTIGFHSSFTSSSSPFVVVECDATCASPGFVTMDLQIVRSGDLTTTDTVYVSTRASTGSDASATPDVDFVSLSNVAATFAPSETTKTLSVRIVSDGVYEEDERFEAVLSNPTAAVTLYDATKVAYVVIQDGGDAGIFAFNASTYTFLENLGTVQVKLVRTGGASGAVTVTYRLAKPAQSTAITNKNFMLLDTVYEVNFAENQREGFINFKIINDTVYEAKEFFFLEISNLSPMKASDPKASIAKYGTPTTAVIFIADDGDAGQFDFAVPFIFCREDSGTAIVSIVRSLGTSTTSYLPVNLAVTTVGTSGGSNATEGGSSAFDYLVKSDKLSWANGESQKTFAVKIFNNNRYESATRAFKIRLASVEGGASIGPKSEMWVYIVDDRDAGTLSFNVSRYDVMEDASAVTIEVVRTGILDSTGVNTYSSGAVSVEISTFTGTILPGRSRYDDNYDYDVVKGLRCTHVSPCDAVPGVAYTPLATTTLSFADGQTSKQVSIPILNNDLFEAPSRVFKVVLKNVKGGAHLGMDYEHPGEWFGYGSDLLALDKRRTELFDNVGAIVVIQDDGDPAVLVTKASLSVSEIGQVDSFGVRLNAPPTTDVTVALTTDLAILKLSTRTLTFTSSNWQDLQPVQVIAVPNQAVQGIYRSDISFTISSTDTRYNGPLRTSIGASGVVFSTAIYTQISGTYDTGNDAHAFQWKETDGVMTSPRSNTNVAVFVIDDDHADLQIEPESSRHQSGTTAPVDYVAVRLNGHKASVDISLSSKPAGAVDVTLVAGDGISVSPASLQFTDSNWNTKQQVEVAAAASAGLSSSNEVTFSTIKISTSSSADSFYHRPNIVAALLRVQRYPSAQVVMDSSLLGTRENDATQDPAAYSLQLGSEPIYWEPKGQYKPFETVIKAEADTMLTFSSDIPVENPPIGIASSIFAAGNSSTSTPQVQYSQLGAMRFRVYPTIPSTTGSQQVGSALLRLYRLSGGENGGLGGISIGVAIASPSTSEWDETKLYASCSASQHAPTTIECSVKDSSTSTLTFLPPGTTLATIASKSAGESLIQPTGAFDSSANSFVPAPGWVTIDVTTALNEFLAQQDLKVRSKADAVQTVTFLVYTRSKATFVYGDVNEVEIASKDHKTVAYRPELRVIASGQVNLAFGAAVTQSSGGSSKAAVDGKWTSKLGVSSSFAMPSTITKYPWWEADLGVTRLIEDIVVVLKQKASTAVLTTVQLPVVVWCFLSDVSLSAGNSGLAGFTAAKTNAMYSRQFKITTRSFTASEDDNIVLRWHVYGEKDGKFGEDRFVTDYATNIEARYLLIQVEGENSIGLNEVEIYQPALSATRISIGGILPSVSFARKEKNELKFVLQQTGDTPDCDLVTEVCRQELVFTSGDWYKPQKVQVNIVDDAVATGTRDALLVHGAQSLDPDFCGSSICDSNQVLSHEPCSPSLFSSSSVKVLRVSDDDENVILFSAPELIVLEGSGVFPNAPESRRLKTVTPTRLRCSTASLTVVDATASSSSVATCASAFAGKSTAWEVCIAKPDAKPMEQGSAWIMAGFPSDQKLTEIVVTVPKMTSAKYLRQLSVWWNSQLDITSTPDSSLLAISNGWTKLTTFTLNLQSSGTQTVKLTNLALQPARLVLFSFEKSYDDANQCLDAPSVAFTGYERVPFPLPIRGDLSNPDAVAPAESGRSRMHRFGTMAVLQVRLASEPVKDVVFSVVTNPNNAALTMFDPTNSANLPSSLKDLSGGVYESGETVTFRMPTALLFTAETWSTPQTLAYLAVDDNIFLSNRTISVRHSATSDDATAKALSQQTFVSGKITRDFGILDSSLRYSSAPFIVSSTHTSVWPHHWQPAWASETGEVKILVVDDDLPGVTLSQNEVIVSESASQASYWIALDSSPLQNVIVAISYTPDPTLFTVQPLQLTFTPVNWNKPQLVSIIPTPNTINDAGAPLTVGYDHLIAKANQPVLVHKVSSTDASYNGIAIGTNEPDRSTPYVTKHGVVVVVQDDDTGCLAEYTCSNGGVCVNITYSAIAQASVCRCPATFGMRDCSAQCVTARDCAFSRVEFRLQCAPGDANAICGDSFSPAKLVSTLYRMLTQNEFKSASDKSFAKLKLGLVSDVMYVVNSTDIACTDTSTPSCVHVVMDFTKTPGADGTNPIVDKLKGYLEVGSLQTQPLFVELLTSRDQYPSNFGATIAVWIFLGFCCFSVAGVTGLFTMRYVKLKKFHVQPQLDDSEDIATAGMTSPAGDVRSRKPPTFPVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGU2</accession>
    <name>A0A8K1CGU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_005598</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000010">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6 16" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="47"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="16">
        <location>
            <begin position="248"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="18">
        <location>
            <begin position="343"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="20">
        <location>
            <begin position="637"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="19">
        <location>
            <begin position="853"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="848"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="848"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="869"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW62980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1408" mass="159246" checksum="DFB4D4A58388CF1C" modified="2022-08-03" version="1">MLTKFESKSNRVKGLAFHVSRPWILTSLHNGVIQLWDYRMGTLLDRFDEHDGPVRGVDFHKTQPLFASGGDDYKLKVWDFKLRRCLFTLLGHLDYIRTVQFHHEYPWILSCSDDQTIRIWNWQSRSCVSILTGHNHYVMCASFHPKDDLIVSASLDQTVRVWDTTGLRKKTVRGAPSSMDDIAPMRTNNHDIFGASDATVKYVLEGHDRGVNWAHFHPNLPLIVSASDDRQVKLWRMNETKAWEVDTMRGHTQNVSCVIFHPRHELIISNSEDRSIRVWDISKRMGLQTFRRENDRFWILAAHPTQNLLAAGHDSGMIVFKLERERPAMDINEGRAFYVKERYVRMYSFLDGSDVPVAAIRRTGTSGTGMGNIPRVLNYNPYDQSSGTNSVLLCSEAEGGSYELVTFTQGSNGETSESSRGAGLFAVFVARNRFAVLDKSRHIVIKNFQNEVTKKIVPPNGTADGLYFGGIVGRVLLHVDDKMVLYETQSRRVLADLQAPRVKYVVWSPKYEYVALISKHSIVLADKNLNHLSTITESVRIKSGIWANSPEEIFVYTTLNHIKYSLTNGDSGIIRTLDVPVYLTHLEGSKLYCLDREAKMRTMAVDLTECEFKIALSKKNYTEVMRMVRHSRLCGQAIISYLTQKGYPEVALHFVNDEKTRFKLAISCGNLEVALNSAYELDDSKCWHQLGVEALRQGNIQVVEMAYQRTKNFERLSFLYLVTGNRDKLKKMLKIAEVRNDIMSRFHNALYLGDVEVRVLTLEAAGQYGLALLTAATHGLAEHVERLSALLQESNPSFDVGAFLAREMRPDASLLVPPPCVSKTENENWPLVEINEPTIQDHAIAAEKREAERSAHQRQETSGGAASHRAADEHVNRKSSMDLGMDAGDAWGDDGDLDLDDSLSLGRPSMDDALDVDFAPAGSTSGFVAAPTAGTSLATQWVRNSSLAADHAAAGSLSTAMQLLHRQIGVVNFEPLKPYFLAVYAGGAASLPTQPNFPSLRAWLQRNDNSQPAISVSFPQLVETLKEAYRAFTAAKFDEVKSNCETILYSVPFLAVDSKDEAEKVKTLVSVCREYLMGCRIRSEVAKFALETEPKRNIELSAYFTHCELQPPHLVLTLKIAMTNAFKSNNFITAASFCRRLLEIQEVATHPRHEKLRLTAMKVLQKAEKEARNEHQLDYQDSKPFVLCARSFTPIYLGDRDVRCPYCQTAYRPEFKAQSKRANVAFKLLRPTEMEATADHTTLQAAQGQQPQGGSTADMQAQFALYQQQQQQFLQQMQQQPNNEQLRAMYNANLMMMQPYMQLNQALFPRMNTPGASEVVEEEPVYVNAKQYHRIMIRRQQRAKLEAKLGNARQRKAYLHASRHRHAMRRPRGPGGRFLTREELEGLSNGTLTFEELQSKHRSTKPMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH94</accession>
    <name>A0A8K1CH94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH94"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23795">
        <property type="entry name" value="UBCc_UBE2G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000025">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="5"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="19163" checksum="EAB4C979F970C832" modified="2022-08-03" version="1">MATDYARELLKRQFIEMSKNPPEGVSVGLGDDENIFRWEILLIGPPDTLYEGGFFKAVLEFPPNFPNMPPKMTFTSEMWHPNVYPNGIVCISILHPPGEDQLNQHETADERWRPILGVEAILVSVISMLSDPNDDSPANIDAAVEWRNDKDGFKKHCRRIVRKSQEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHK2</accession>
    <name>A0A8K1CHK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHK2"/>
    <dbReference type="OrthoDB" id="117714at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="389"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="844" mass="90971" checksum="5665B809EBF1BF4A" modified="2022-08-03" version="1">METAAASKRVGTRSTRATSQAASEVKDVVDNTLAESLLLEGNIEGVSASESAKSTETKTLDDGAAQAPRRSSRRAAGSSTTATATSSAKVANGDGKEAEPEAEWTDSEVYKFVQQGGSVAAAAAKFRISRAEVGKIMKEHSDSKASSGCSGAATDDGKPNDVGSDTKSVAAGEVTVAGNNAQKRPAADTPAGTTTESGASVTAPKAKRVRKTREEKLAILQFVDQGGTHVAAAEKFGVSRTAVTKMVKERDVISASVSTLPVVTPVISIASTPTTPGSDAPVTPVAVVAAKKDKKRPTSASSATRRSAGKTEASEATEDSGAEPTVPKKTKRVRKTNEEKLQILEFVENGGSQGAAAEKFGISRTAVTKMVKEKDAISAQVLSGMSHHRKVLQYQHKLSIIEDTLYKWQMQVENDAPTLKFTGELLQRKALEFRDKILADFRDQLQPEVVQSLTDFKASNGWLHRYMQRRNLRSAAAQDGMQRAASGAVLPAAMSMPPTVLDPTDIQFYFAAIRQRIASVPVKCIWNLDEVALLSRSLALPTFEPNSTETGAEDRLSRVTLSLMVSAAGERFKLQIISEEDLPTPDSATTDIPFVLSGTHRASWQDTSSLAMYLQLMSDEARARNETWYVIMDASPAHSAFVHLADPAGSFEQGFRFESLVLFLLPAHATNEHQPIHQGVARVFKAAYRQAVLHFVAEWLKEKGSENPDFDFSEIATPTVVMDWIMKAWEAVPGPLIRHCWVRNGLLSRSQLTEISHDNSRAVEAELFESLHRSLGQVAAAENGEIARRLGLAIASGQEITPDFMNALISLDEHELTEPRDDVRMGVSSNMSDMYSVGDLGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHN5</accession>
    <name>A0A8K1CHN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHN5"/>
    <dbReference type="OrthoDB" id="10262814at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF20">
        <property type="entry name" value="IMPACT FAMILY MEMBER YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="2">
        <location>
            <begin position="47"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="UPF0029" evidence="3">
        <location>
            <begin position="155"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24527" checksum="4E741B65864E46FF" modified="2022-08-03" version="1">MAARTIRRRVEYEIAKRKGSRFIAAAWPLDDDTSGDATGSRREALVQQQVKLMLDDCRHKFPNACHHCYAYTTSDGREYCSDDGEPHGTAGKPILAAMQRAKLVDVCVVVSRIFGGTLLGTGGLIRAYGAAAQELIENTEIVDKVPMRVVYVQSSYAHVDLIKQSCARFLGEIIAQSYAVDAVFAIRLPLEHDAAFRDVLQSRSSGGVAFPEQEPPELITPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHR8</accession>
    <name>A0A8K1CHR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHR8"/>
    <dbReference type="OrthoDB" id="4421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF51">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47901" checksum="2564E969EF728337" modified="2022-08-03" version="1">MTRHWSLDVETGAVLELVHVRSRLRLRALVETKSDATQAVVLSLCHLERPYEKLRVALNKQVGWATAAAKFAAFQVEDASTEEMESVYDDISRQDVVCVHFKAVAHQKKLNREDTLGWYLGVSNEVSETSQQYELIGDAARGTDSLFSLAIVSKRGAFALNSERTLFHGAFRTDPSTILTESQRQAFIRDGYLQIRGVVPIKLVNAALRRINHELGIPGRMVDGGVEGAGKLAGNISNSEEVLNLFHLSDARAYAEALVGLDKVVPPRGAQIAMRFPELGEPRDPQGTEWHTDGMRQGKLHPFTLLVGITLSDVREPLAGNFTVFPGSHLSLHKLLRTDGKLEGYEDECYRADSVWGDGTLPDLGVPVQLLASRGDIVLAHPNLAHRGGLNFSPDIRYQVYFRLKHVDHEQLQVDAAKNLWVDLEGLHGHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHW4</accession>
    <name>A0A8K1CHW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">MyTH4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014804</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHW4"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00836">
        <property type="entry name" value="FERM_C-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051567">
        <property type="entry name" value="Unconventional_Myosin_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692:SF33">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692">
        <property type="entry name" value="MYOSIN VII, XV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02174">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21989">
        <property type="entry name" value="RA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01244">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MyTH4" evidence="11">
        <location>
            <begin position="118"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="FERM" evidence="10">
        <location>
            <begin position="274"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="65944" checksum="4129248B98A36274" modified="2022-08-03" version="1">MLSLASAASEEPMTNSAAIEVNGGGDDASDLPSQGTQHDEIQVNVSDAVPTTKLGHLDPVPMTPLNVTEDMAKKKEDAHLFEKYPLYGFARDHFLLSAPRKFPFGRAKAFNLEARLQWERELLTSPLTKLTGDQAKLALQAFRNISGFMGNRSSGKGQIDHCFKLLRNVMPKPTAIKDEIYCQLCKQLTRNPNSNAALNGWLLLHACVVTFPSSKALSPYLESFVMSHIGVTESKVSQFASGCLAALHHWTKVSERKELPSLREIEALRDLTNVELSISLIDGSTFRIPVSSWTTCGVLNEMVAVHLGVCKKPAFTLFDVSPTGEEHRVEHDERVLDLLALWERIGIEQLPKKKKKKKGNAPRPSKPAADLLTATHHLRYKVYLHLPIDEDMLEDLQLFYLQAVHDVVNGGVVCSHDDCVQLAAYQLQIASGYGSTVKLEELSRDLHKYVAPNLISKANQLDMAMEVLDAFATLSDQPTQQLRRAYLRICDTSRLYGATFFPVHNTRTRSMPSEIVLVVNHKGISLLSLDNDSTLHHFPYVSIATWGYSSASFVFVVSAQEGEEVEYVFKTKMGKAINDVVAAYVAYILSCEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CII1</accession>
    <name>A0A8K1CII1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LRRNT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CII1"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000372">
        <property type="entry name" value="LRRNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00013">
        <property type="entry name" value="LRRNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469009" description="LRRNT domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="LRRNT" evidence="3">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="19352" checksum="4DE055C0BE9D7ACF" modified="2022-08-03" version="1">MQWMGRVQNLFAVFLLSACAETWGCPTECQCIGRVRVTVYCDFKDLEKVPENIPLETTHLFFMGNKFRQVVPAMFMGNVKKQDGTFLPEKGSLDQLQVIRLDLNPITIVNEHAFDRAPSLKLIYLPFDVKIQRQAFAEMKNDKQTFDGFTRVPIHPLEDPQFAAFSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIS0</accession>
    <name>A0A8K1CIS0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Feruloyl esterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012814</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the faeC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIS0"/>
    <dbReference type="OrthoDB" id="122995at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF1">
        <property type="entry name" value="FERULOYL ESTERASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23068" checksum="0CB176D196031EE7" modified="2022-08-03" version="1">MAFHWYGGSMEAIELESTELGNGSYFGLKAFGGDSTIFVAPQGLAYGWANINNDDLAFVDAIIKTLDNGLCMDTSQRFAVGLNYGGSLVYDIANSRANTFRAAAILSGSVANTYTGKTGAISLYVQHGMSEPGNPITEARTIRDRFVEANGCASQTAKEPAPGSGTHIKTEYKDCSSGKVVTFVAFDGVYQYAPVDAGSKTSWSGEEIWKFFVNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK79</accession>
    <name>A0A8K1CK79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK79"/>
    <dbReference type="OrthoDB" id="148079at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475461" description="Apple domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="146"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="24028" checksum="5B371C0A751169E8" modified="2022-08-03" version="1">MRWSLLLTLLSMATLSRAADERTCGKVKLFTFSDGEIIAVTNATKREDCCAQCGETDGCKVINYGGVWKGVGSQCYLMRNVRQEIPATVGGPVYETVWMSDYDGECNSQKWGVCGNSRGSSCCPNEYYCQPWNPDFYQCVPTPAQCEGLETDIDYYGNDLFRVLGISPDECCEKCAATPSCKTYTFIQQAVDGSQCYLKTSDGGRVRKVGAISGSVVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKF2</accession>
    <name>A0A8K1CKF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009336</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKF2"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="652"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="796" mass="89253" checksum="0222AF5E33077C0E" modified="2022-08-03" version="1">MPRFLTDIFTNLKHEPSLRTIRVSFLEIYCDTIRDLLDDRADKQLVIRDDPHNVWVENLRQLPVESLSKALELMNIGRSRQATGANALNDTSSRSHAIYTMEITRKFHNESKKSKLTFVDLAGSERLKKTLVEGAQKRESIQINGAWDELGLLALGNVINALADEKLQQRRKSREGIQIIAENGSSGRPRSPRATSSDGFIPYRSSKLTRLLRDALGGNSHTLFIACVSPADSHAEETLGTLQYANRVRNIHNKAEKHIEADQPVLSSSQIEINRLQDEISRLTHRIEELTSAARIREEESAQAEKDREDGERLKRENKRDVSVGTNEEGKRVGIDAATMTEQEEPEKSECVDAECQCHAQMEDGTTNTDMTEQPQISVADSATTTIELSNHEVATQTATIILSDKATGSLDISVYQTEEISCQTDCVMGIFEIKEEHVLIGPSKAPEADAVSESSWVSDETHSTSNPVTSYDFEEITKEDIGDDIEMKDDEFFSDTGDNQPDTSELGGLAVDKKAPPLSLTDLHDLEPQEEVCEEPITRDFVVLRSLIRDATPTQRMASPRRTMVKASPSTVDLHVHPMKLFALDECLLSPMSPSDHLLAQAQALSQNLLELTTEDYGASSGDEDDSSDNNAAQEHLPNTRDSMAALISTSEQLLRRRRRQRLRVSQLRRQIHQLEAVLGVPTKDRLRNDDPALRAYTLRGQVEFLTPILHQYEVLAAARLQARLSARVEAELLLQGVHLSNFLDEAQCQACSDWFFSRRKDLAYFRSEILPLLLAGWISVAPEDLEAEEMWLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL29</accession>
    <name>A0A8K1CL29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Coiled-coil domain-containing protein 124</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL29"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054413">
        <property type="entry name" value="LSO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22048">
        <property type="entry name" value="LSO1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LSO1/LSO2" evidence="5">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28990" checksum="23142E48111BEAC6" modified="2022-08-03" version="1">MGKKGGGSNVNTKVEAANAKKAAAQAVKNAKASAAAEAAEAADWSKGSDARGDRRRQEEERKRQEAEAKKAELKRIQALEEHALEKMEDKSAIRKNTTKAKKEVNKPWEEALKPAVKKSNRGARAAPAAASTAPVPHNGKVTQAMIAAKKEAEAAKAAKEAADRAKGITFGNSFTENRNRSIDVEGEARSLEAALDVLTTDDTAQKHPEKRMKAAYKAFEEAMMPQFRADFPGLKLSQYKDRIFEAWKKSPENPMNQASLAYNAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL45</accession>
    <name>A0A8K1CL45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL45"/>
    <dbReference type="OrthoDB" id="4567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031703">
        <property type="entry name" value="Lipin_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16876">
        <property type="entry name" value="Lipin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="6">
        <location>
            <begin position="432"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="692" mass="76997" checksum="D4D450CDEF547B68" modified="2022-08-03" version="1">MNVIYSVKDYLFNQATVSGAIDIIVVRHEDGSYRCSPFHVHFGKMELKKNTEKQVVLKVNGSTVEGVHMKLGAAGEAFFVDSVESPVEEDYSTSPLASPSSSPVPSRGGSPSQPSTFETVVRRRSISPPAPEWHDAYRLVPEGRMTRRESHGSSDRLTWGWGTLPMVRTASVAELNGLSEESRASGDNQPRMVKNESIYFDALETVTLNPSTSSSDPPCMSLCGHLLEKAESREQAHTIFSEHIVPYEVFKENPAEMLQDDNLRFLVDGKIYPFNNEIQAYLVSRVLFPNSQPPVLTSAWAPKTRSRRSSGKIESGFWFDEEGDTDVEDDDSDCSEQDTQPSRRWFQWLPRSSSDDESSPLSRPLEVGKSLRSESLPSASAFYRKTLVPTQDDLEKMNLRYGTNEIEFVVCTADCVHRVSAKLYLWPVSAKIILAEIDGAISRQPSGRRLSTLLPIMERDTAGPHRGALDFYARAARNGYRIVYLTGRGLSQADLIHDMLRSSDKSKLSLPNGPVLLSPERLLETSPDDQAVTKDFKVDALNGIRALFPTDVNPFYAAFGKTYADSAVFTQAGVFPGKVFLVDEGDGRLRHQSIINFKESYSSLLDMVDKMFPPICSPSPSHKSMRPNSQPNQLVLHSSSAHACPSPIKRVHSATENLVSDVVSSHVQTRSMGDEAYNDVNFWRIEPGRIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLG2</accession>
    <name>A0A8K1CLG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_003576</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLG2"/>
    <dbReference type="OrthoDB" id="3784at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="15">
        <location>
            <begin position="78"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW65811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="335" mass="37774" checksum="62218682DB635FC6" modified="2022-08-03" version="1">MPSEQLSQALLVTCASVFSVGAVVFLRWFLAPIADANRLAKESDPAQELTFEDPNDTNDKTKHHRFGSLADDATRSLTVILPAYNEQDRIIETIRDTVKYLDERKKTDASFSYEILVVDDCSTDRTVEVVQTEIKTYTVDRIRLLRLMKNHGKGGAVRKGVMRALGERILFADADNATEIRDYAKLESAMNEAKIEGVVVCGSRAHLEEQAIAKRHPLRNLLMHGFHVIVSVLGVKSIRDTQCGFKLFDRAAARLVFAPMHIERWAFDVELLYVAALRSLVVKEVAVQWHEVPGSKLSVVSATLTMLRELILIRLCYTFGIWRVEDGGFRLSRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLX8</accession>
    <name>A0A8K1CLX8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLX8"/>
    <dbReference type="OrthoDB" id="70500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="58887" checksum="5EDFC42982F7BC52" modified="2022-08-03" version="1">MQSPYEVWARFDVEKELERVDEAEQREQQVKDQEKKVVEKRRVEDSISRSTEQSAEVLAAQAAVAALKAKGRGRRGQTRKAATTSQQEELDVNVQSGEIPKEPVAIDELERRAQLMKRKHDLIMEILAMRRTADAKVKEASEGSTAKWLEAQLHYEKAIEAVKALEEMIPHLQEIDAEVANTSTSQPHDVHGHDDHKEHSAHESKDGKSHDHHGGCGSGCSRSHKHRPKKPKDTEASLPKPNDVKAVVTMFAKDCYLGLGTCELAQRRLAAASEAFKEVLLRDQNHVQAWMQRGAAFEAMGAPLLAWLHYNRVTGMEPSFDEGKQCEERIKTKLAHGKGHSTSDHSAEVSHNTSSSLKSRLDAVRLLVDEGHVIMVEGFYAYAITKFEAALQLMEALTSDDAFAPHSSVARPIIDKLRVACHLNIASGYYEMQKGYAVGRRHCLAALQIDPKHAVTLFRLAQIDRVAHDYEQALQYLDKCTAALTDPTSDTIDKIARERDKCLFEQSQYDAVYIRHQLNAIKEAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CME6</accession>
    <name>A0A8K1CME6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CME6"/>
    <dbReference type="OrthoDB" id="66938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="41687" checksum="F0507EF15DF0C80E" modified="2022-08-03" version="1">MIGRQPTAARTLFGFTNSDRFARFQQSVQNRFEQLTTATIASAHGSIPPPPGSVSCALQSTFASSNGGKLVREDSKTSTKAEAENSDLVLIGIDGISLHIASFLDGQSLGRMQLVNRSWHQFVSQHRDGLLQALLDRCFETVITSSNTFKTFLFTLRHELDLELAHTRYIEHTHAALEDYCSKTEPTNHGFIAMFCDIIRFRDPRIARFVAHRRQAALGMVLTSTPDHVYAFRRRCKYAGPITFVPVDNPHWPEFDLPPVNFPGFLGYAFEHVEMVKGYESLKYTVVKSILKELMLFDTTENAEAYGRAIGREPFAAVLDAEHTGPNYHLTFSNPLREELRHLPVRERVQRLLKRIEAIDHSISRCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMF4</accession>
    <name>A0A8K1CMF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004086</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMF4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="8">
        <location>
            <begin position="150"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="631" mass="68106" checksum="7739E53623D039E7" modified="2022-08-03" version="1">MASSPDKVPDHGSIDSSKLVQVVAAETKTDESQPVDSPTDARSFDHAAKLELAAQEVSAAEQVEDAPAAKPDSSDVNPVKTEVSDLRIQAPESGVSSGVPTSTPGPLTSPVSVLSVPTSPADDGLDTPESEASGAKRRRVESDAAHPHATSPLFLEKTYEMLDKCATHIACWSSAGDSFIVKNPIEFAENVIPSYFKHKNFSSFVRQLNFYGFRKVRVVDPEVTGGVDPKDWWEFRHEKFQRGRKELLKEIKRRSLHANGSSGQSDGRPNIDRGEIEDLRSEVCTLREQIQQLNKHMIGVMQIVMARNQTAPGGPGAPPPVQGMPMMHGMHHPGVMFHPNMPHGYPPHPGHHPGSMPTSKNDKNTPPLGYPLRPVQTLVGHGPGGHVPYMHPPAGGPHPGMDWEAYHRHQYEQHQRFLNPYGVPPPSQSTASTPTATTSVPAVTGLKRSRASPSPAGGMHPGSGPPMAGVPGSIPNPEDAVRHMSMMVTQIRNDLLGCIIGRIIAFIRVQPPHQKAEITPEVNAVADAVNGDILQRLVHINEAEAATHGKPPGSAPSETSLMYRVEILKFVSKELPRAVQESVEKRLPPPVKKAINRSLLALMVQKAQAALENQMRIETASSPGGSNASVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMU6</accession>
    <name>A0A8K1CMU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Major vault protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003985</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMU6"/>
    <dbReference type="OrthoDB" id="6125719at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08825">
        <property type="entry name" value="MVP_shoulder"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.570:FF:000002">
        <property type="entry name" value="Major vault protein-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.550:FF:000001">
        <property type="entry name" value="major vault protein-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.560:FF:000001">
        <property type="entry name" value="major vault protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.570:FF:000001">
        <property type="entry name" value="major vault protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000010">
        <property type="entry name" value="major vault protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.560">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.570">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.550">
        <property type="entry name" value="Major Vault Protein repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039059">
        <property type="entry name" value="MVP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041139">
        <property type="entry name" value="MVP_rep_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043023">
        <property type="entry name" value="MVP_rep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021870">
        <property type="entry name" value="MVP_shoulder"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041134">
        <property type="entry name" value="Vault_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043179">
        <property type="entry name" value="Vault_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040989">
        <property type="entry name" value="Vault_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041136">
        <property type="entry name" value="Vault_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002499">
        <property type="entry name" value="Vault_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14165">
        <property type="entry name" value="MAJOR VAULT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14165:SF3">
        <property type="entry name" value="MAJOR VAULT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11978">
        <property type="entry name" value="MVP_shoulder"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01505">
        <property type="entry name" value="Vault"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17794">
        <property type="entry name" value="Vault_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17795">
        <property type="entry name" value="Vault_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17796">
        <property type="entry name" value="Vault_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51224">
        <property type="entry name" value="MVP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Major vault protein repeat" evidence="10">
        <location>
            <begin position="53"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="8">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="MVP" evidence="7">
        <location>
            <begin position="123"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="8">
        <location>
            <begin position="168"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="MVP" evidence="7">
        <location>
            <begin position="171"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="8">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="MVP" evidence="7">
        <location>
            <begin position="224"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="10">
        <location>
            <begin position="275"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="MVP" evidence="7">
        <location>
            <begin position="280"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="8">
        <location>
            <begin position="326"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="MVP" evidence="7">
        <location>
            <begin position="329"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="12">
        <location>
            <begin position="380"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein repeat" evidence="11">
        <location>
            <begin position="466"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major vault protein shoulder" evidence="9">
        <location>
            <begin position="528"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW66220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="859" mass="96394" checksum="5B90EBB914757333" modified="2022-08-03" version="1">MHHEAGGPRVIRLPPYKYVHVLDTNSNVSRVLAGPLTYTRQEHEQVLSQPQDMIILPAQHYVEIRNPVVRADDGEIVRDQYQQAKLRHGEIEFRVFDQYPDPFPLYPGEVQVGLIQKLRVLPVDSALRIRATRKFDKYMAGDEWLFVGPATYYPRVEEEVVAELSAIIIKKNQAIKFRAEKKCKDSLGNLRDAGEEWLVRTPGAYLPQIDEVLVDIISAHILTERTALHLRALRTFKDIYSIQRKAGEEWLVTSDIAETHVQDVHEEVVGTVETITLTNRQYCIIVDPVVDGVQKRGTRELRKGEASFFLLPDEQLEDDEIKDILILSDDEGVLLQANEPFTEKEDGKDIKREAGERWMVHGPREYIPPIQVEVVEVRKAIPLDSNEGVYVREKKTGQIRAVKGETYMLQPTEELWSKYLSPEVEDLLLSQRAGSAYVQDPTESTSWASSLGPVAKHNRTRDPTRVVTFEVPHNAALQVYDYKTKSSRILFGPTLVMLEPEEQFTVLHLAGGVPKQPNVIKTLCLQLGPDFMRDQIIVETSDHARLRLTIAYNWHFKVNQLDHKEATKVFNVKDFVGDACKTLASRIRGAVAVESFDHFHKHSAKIIRTSIFGVDENGKLRPSLLFDANNLCITNVDIQSAEPVDQLTRESLQKSVQLAIEITTKSQEARAKSQAMKEEEEAKGQLLTQQLENQAAAEQARKNLVQLSAECAAVEAEGEAVGKAKAAAQAAEIEGLAAVRQAELKAQADRIVHEANLARMREEHELQIAYAKQLSEVEVHKKRELMSIEADKFQQMVDSIGKATLVEMARVGPETQVKMLEALGLNGYLITDGKSPVNLVGAAEGLISKIANGPSIASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNQ5</accession>
    <name>A0A8K1CNQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="318"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="600"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="877"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="956"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1038"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1050"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1326" mass="150047" checksum="B3A49F039109A516" modified="2022-08-03" version="1">MSIAGPLYRRALRPAEDNEVIVTWTLVWCELAVERGAFCVFPDAHSTQTRHLLVLPVRSSKIKQVRSNGRDCIEIKCHGKTESFSSHESSYDVDWWMNSLTAVKRDLAGGVTPQLSIVCPPGTDTPLRTKPRGDTMSSSLNSVSVRTQTRRRQPSLEATVTKFERYTIYETVTKFYVVCSDRHYTRFRKFSLERAVDPPRCLAEVLKEDPELYTWEEMEAQLQTLAEEAKAVGCKFSRAFTAVAIVGCIRFLRGYYFIFATQRRKIGCIGGNHIYGISATQQLSVSRSTEESTAWTWLNRWLNPSPEEEAEARYLGLFHFIDLTKDFFYSYSYDVTHTLQHNMTTDASEPCEMFTWNEYLTREFKSCLSVGASEDLIIPLVLGCYEQRKCSVFGRLVSITLVARRSRHFAGTRYLKRGVADTGKAANDVETEQIIEDENMGTGKFSSFVQYRGSIPVFWTQETSATLPKPPIVLNRIDPTYTASRKHFADLFSRYGSPTVALNLVKQSEKKEREVIVGNEFMNAVEYLNSFIPGEHRIRYVALDYSRLSKQKGLNVLHSLDKVAVWALTQTGFFCSAPKRHIGRQDSKQSSYVSFAPPLSREVSGATSDGDGTQENDEVSDAGPPESPTIPRKSGDWLEQKGVLRTNCIDCLDRTNVSQFSVGMRALGQQLYAMGIRNTPLLESRSQLVRVLMLLYSLVGDAISMQYGGSEAHKNVKNSAGRENVKGRELLTSIRRYYSNSFTDMAKQDAINIFLGHFVPKEGEPPLWELESDYYLHNFEVRNGTAACDLVRHTLEVQAENKRRALDGDVSPSSLAEAVTARSNERTSDLFDDHITLMSLTIRDKQKREAYVRECRRLLEDWWKEPLDEFERPKFCIPRDRPKRRPRSTKQGDGGIDSTLTDSMGPDGYIGSRNRLTKSLSVSSDTFLQMYHPEEMTSFTKTLGYKFMNIMDLSNESTNEEKTRSRSNTSSSIDASPKVGVLQTTRFSSIDEEDSETHEDIVIAPRSSAPNSRGFRSMSAPDIGDELLRSEAHRRLLEHNARPPRGGDGGSRHPEKDPRDAYASRDGAGFGRSFQIQRSSTRVNDDSTHMSNFLQGRSHRKKFVGDCSPLPTESAYERYVHWDQSFSLWETGNENVKAHFESYLRDNNISPDDARALREAQTRAGATFKIQTGTYSGLDQNVKARVLVAKKLRTDLDDRKAFEECLDYKRLMSSSKATIPSESVELYKSFFDQPLPEVPIYPKPDAVSATKNSSEQMAEILRTGGDKQRRQGVRGRYGDYDLILVGPLFKLNGGKDEDFILFNEAAAENAFADVIKNETELSFYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP19</accession>
    <name>A0A8K1CP19_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP19"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="432"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="926"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="737"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="860"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1234" mass="139483" checksum="09AA8BA24226B355" modified="2022-08-03" version="1">MDDLNQFLNSVEASARRILKQQHKKQQEAIQRDRVALVRASRGAPSNAASSPTASNAPSITREQLKASYSPGGALIVTVPPPPLSPHRRSENEDDDRTVLPRLPASPSHGNRDGSTNGTSSSVPLSLPAIEAKRLKAKREKRAADKIVNSPLYKSLAKSKFESTQGFQAPTNIKKTLQDVDQVNMLLKKIGMRDNSSPTRRPDHAAERRMCNACWADPTKLTGCEHHARILPQSGDAEMLRQMELQGPMSWRSDDLYVKFRSEMDRERLFAAFLRLKAAQDEQQQQYYASSDVPVIPIVVRHPIYAKFFTQIELENLKTQAATRRRNQTKIFIFDVNHLWLTNLDHFNTRLVKQERLVVRRQRRQEQDDGDSFAVSALPMAEEEEEGAEDEPLALRDRRDENAIRSGYSQIQSIATARALQHALFPDAETQMATSTFKSQAGTPPLPASSSPPKRRKRPNEAIQKPPLTLLVCGAWSPTDPILIKSLERVPGVALVGKALYLLWWLPSLREPDQETQTVALFARSTTLSSTNAILVSLVLALEATLRAPLWFAWHPGSKIPPPQNYEAPGPLLTPPRRMSPCFTTLLSTKLETRLDTLLPGTIMLLNTIAESEDHVIDLPEPYGHRRFWTEFTADAFRQWWLVKQYAIPAPYDVTPQPCSVLMAQPNATGVGGRATWHSIDVIQYQQHLNRRRVEKDYVYLVLNTLTRGSNDPLYVIVSLNHEVMQDVRLARLSKYLEMIEERRRKQEYEAKLLEIEHKIELGRLQLEAKRQEQQRLSQLLDAKAALANERLHGERSSMTDAMLMEWEARLQSSTVEEEQVGWQRRMITQDESDVVFYYALNESLPRRLCFAWERPSDWVEQEEQEELSARTETSDLEEDDTVMLQEKQQQAQDAVTQLAQALLADEQFLAVLKVKLGLDIELTESEQEKKAHRRRSTLNNGAGEDDSSENDRMDLQDHLLRVTQHEDPLRGSLMALKMAKLELPAAVIPTKLLRGEGWKRLKVSRLPKNFARGVYSRHTEGPRSAFINQTNTATPVGMLDPREASPYEPPEFIPELRTQLIPKPNADLQERKLQHAEFVANHATAVSATPERVISRAQAAKDALFEKDPVELEHDLEQLVGRAVLAARNNNLQALEDALDGGVDINSRDNHGNSLFILVCQQGNKKIAKFLMRRHADMNLQNLSGNTALHYLHAYKHKDLAEYITSKGAIDTIANAAGLTCYEGLSVDQAEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPN8</accession>
    <name>A0A8K1CPN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPN8"/>
    <dbReference type="OrthoDB" id="528635at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14587" checksum="6C65404C6F69BB34" modified="2022-08-03" version="1">MLREAHKVKAHELRSKTKDELLTQLDDLQQELAQLRVAKVIGGAASKLAKINVVRKSIARVLTVYNQTQKAKLRQALGSNKYVPLDLRRKKTRAIRRALSTHEKSLKTAKQQKKEAYFPKRRYALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQB9</accession>
    <name>A0A8K1CQB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQB9"/>
    <dbReference type="OrthoDB" id="10267381at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052164">
        <property type="entry name" value="Anthracycline_SecMetBiosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993:SF14">
        <property type="entry name" value="GB|AAF24581.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33993">
        <property type="entry name" value="GLYOXALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="123" mass="13512" checksum="20ACEB71DE5F888F" modified="2022-08-03" version="1">MRLRQVLVLSRDLARSTQFYQEGLGLKLLRSSDTFAEFDTRSSVPLCVKLAQSEAACSTGYSPFLNFDIQDLSEAVPRLLMLGAIMDGPIKYPAHGKVAALRSPDGVMIGLYEPNSWENVTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQC0</accession>
    <name>A0A8K1CQC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COMM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQC0"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07258">
        <property type="entry name" value="COMM_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21672">
        <property type="entry name" value="COMM_HN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51269">
        <property type="entry name" value="COMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="2">
        <location>
            <begin position="127"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="548" mass="62075" checksum="E1E5CB7D88643355" modified="2022-08-03" version="1">MTSATETTRATPSMQVLNRIAKDKIAQVLVHVLDRLGAKSETVFSVEEAEQLQSMLGISEYDVRDLTVAASTIFREAAAFGSISREALAAQGLSVGVINVLEKTWRKKGKAHADVIATTFPLQPSHTLTNTEWTLQVELGQRYLSKQTSPAAIFQLDLASNNGPTEPKKEKIALEMNHTELYTFFRQLNAIQSELDRVPPELPPGGTILYFKLYYLEIMTEGFYSAERGASTLLRALYASSASAPGTKSGDVASPYELLGDLKRQNGADTNAEPVEFQGIRLRDWVIGCNKTHITPIDDLDKIAEEAKMTPPEMVFGKNQLVFYHEPSGVCYNFLAVEALKGAHFAPPESDQAADIVAQQQLKVSVAKHNTNKEDVKELDIKYDWTYTTDYKGTLQRVVRQSSESEELALERVEDVQTEVTEERIDLNKLREREPILWFEDVGLYEDELHDHGVSAMSVKVRVMPSGFYVLCRYWMRLDHVVVRLHDTRVHHLFGRDYMIREYTRKEEQFETLFAKGHPRGMANYTNIDTFQQHLPIREAVIEKIRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQL1</accession>
    <name>A0A8K1CQL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purple acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQL1"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487056" description="Purple acid phosphatase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="6">
        <location>
            <begin position="66"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="176"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="5">
        <location>
            <begin position="438"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="54953" checksum="DF693A761DAA06D0" modified="2022-08-03" version="1">MRLLSLLAVLGGAAVATAQAVDDKACVFSLLQLGCVPKALCKFNYNFGDLTPSQSCRVRPGANKLPQQMHLAYAGATAGSGMTISWATFDDVSDSAVWIGSNADKLEHRPDVAVSSNSYYSEDKYSLYQHHATVLGLQPNTKYFYKIGSATNSSLVSEVASFTTARAASSNDSFAIGIYGDLGFGTKGEASTQYINTLAEKLAFVYHVGDIGYADDDFLDPTQALGFFYEEVYNKWMNSMTPLMQQVPYMVTVGNHEAECHSPSCIVSKFKKDRLGNYTAYNSRFQMPSTESKGVKNMWYAFEYGPIHFTSISSETDYNDAPGNAYTLTHKNGGFGNQLTWLEEDLKKAAANRANVPWLIVGMHRPIYHRKDADAAGQPVGDSLALQKAFEELFIKYGVDVVLAGHEHSYERHFPIARGKAVKDGVSPDNAVYTNPKAPVYVVSGAAGNPEPNHASGTGQVSWNVMESAEYGVTILGVTRQTLTFTQLTAGDEKVIDSFTINKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQM2</accession>
    <name>A0A8K1CQM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cilia- and flagella-associated protein 36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007703</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQM2"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000109">
        <property type="entry name" value="WD repeat domain 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059157">
        <property type="entry name" value="WDR36-Utp21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25171">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR36/Utp21 N-terminal" evidence="12">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="253"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="509"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="552"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="594"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="10">
        <location>
            <begin position="740"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="domain" description="BART" evidence="11">
        <location>
            <begin position="1060"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="818"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="842"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1188" mass="133439" checksum="2358EB501C756425" modified="2022-08-03" version="1">MIVDDLPIVWYSMGKESFAVASLGKSFVVYKCDKLTPVLVSPQLPKKIVALNVLPKKQLTFTACGREILVWKRVEHVHTLSGHKGTIKQLLTVGTILFSLDDARTIRIWDLETMEQLNELSFPVTFTPSVMLHPSTYLNKILVGSEEGALELWNIRTMKCIYSFKGWNSAVTTLEQSPAVDVVGVGLANGRVVMHHLQFDKLVLDFQQEQGKVTALSFRTDSGASAPFVVTGTTTGDIAVWNLESKRLESMIPSAHQGAITSLVFLQNEPLLLSTGVDNSIKMWIFDHLTGGTARLLKSREGHMAPPTRIRYYGNNTLATMADGADGTSCQILSAGQDRAFRVFHTAREQQSTEMSQGPMLKKAKKLHVRVEDLKLPPISQFAAMETRERDWANVVTCHENESAAYVWRFEHRAIGKKILRQFDPSFRVTPGSEEDLRRQKTQATCVAISTCGNFALVGSIGGAIYRYNMQSGEKRGSYPTAATPKPKMIRALTLPGSEIKEEEDHSITHIHDGPVSGVVVDALNAQVVSAGIDGKLKFWDFRTQALLFQIDLGNDSPISQIELHRDSNLLAVASDDQVIRVFDVQTRKLVRRFQGHNHRITDLQFSRDARWLFSSSADASLRVWDIPTAKCVDWVKFQKPVTGLTVSPTGEFLATTHVGHVGIYLWANRAFFMDVFLDSEPQEPVLLDMPVPLNEVENEDALGYGTERNPVVVVKNGEKVEETEAPQADENGRVEVEPLDSSLITLSNAPRAFWESLFHLELIKKRNKPIEPPKAPEKAPFFLQTARKDDVNPTFVPVGDLEQKDEKAKKQLEGVIDTTKAATDKEDDEDDEPAMAGWGVGDDDEDWGPEGDDDEDEEEVVKSGTAEPVASGSRIYKSSGMITSRCKLATLLIEAVENEDETMEIEDSCHTRSRFHRVALYLQTLSASAVDVELNTLCMGDFDDEGKELLGFFLQFLEDEMATRRNFQVLQAYLNRFLKLYEQLLVANPELLDRVESLCAVQQRQWEHLQQLLHNNLCLVQYFSKIQMWSTQMYPFRGGHFTPRATMADQEVTVGIPSSDALIARLVAFCSGSSIEATFATFYRKHADKFHGFSADEEKQHLVYEIFQEYELVFERVINDFLTQEQMAPDEFFDHCRRLLRSKKQEDAATNLHIVLSAMDFDAFCVLMEREAIETQQALKAAEDMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQX6</accession>
    <name>A0A8K1CQX6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQX6"/>
    <dbReference type="OrthoDB" id="159229at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456905" evidence="1">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="23657" checksum="F342CD5ECEA8163E" modified="2022-08-03" version="1">MFRLQALLVCALSVATASARDIFTYQFDPALAAGIQGAIKVKYVDEKSSKATISADLDFSKVDLSEIQKFDGNCTSEIVEYKWHIHVKWSSPNTSDKLAQCSKAATSNHYDPLKACGPNSEYAETPECLPKISSYACNPANYTKDPLTCEKGDLSGKFGGFKLDANKKASGEWTDEHYPLVSENTPQWNMILHAVCGKATPRIACAVAQKEADSCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQX8</accession>
    <name>A0A8K1CQX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQX8"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="59"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34301" checksum="011262C8D0FB0D48" modified="2022-08-03" version="1">MVLMNALRRTPLLAARGRRCVSTSDLPSHLKSVRVNVADDVALHAIVPVEKPSPSAGHPPILCLPSAFGSVIHNFRHQFTALSEEFEFIGVDPRGYGFSRPPERDFPDRYFERDADDVARAMDALGYDKFSILGWSAGANTGAVFAARHPDRVERLVLVNGNAFVDMDDAETYEEFEDIDKWHPASRDEGIAIYGAENLQKGWSSMMHKLKSIYDDEGGDLYCGSLPQIRCKTLVVAGGKDRLVPEFHGEYLNERIMHSKLHVFPNGRHDVHIQEAAAFNQLLEQFLTEPDDKHTQSREFVARPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR20</accession>
    <name>A0A8K1CR20_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR20"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="681"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="101"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="707" mass="77486" checksum="265711A1EB44336E" modified="2022-08-03" version="1">MSEYALSLYTIDSDKGWVWYGIIYIAAMILLFVYISSWILEHFRYENTHSLTTNEDRMPIASTADSADSYGLVETPRSHESDVMLDIQTETHHHRVAPLTLAFRDLWYGVPDPANPKQELQLLKGISGFALPGTMTALMGSSGAGKTTLMDVIAGRKTGGTIRGEILLNGHPASALAINRATGYCEQMDIHSEASTFREALTFSAFLRQSSDVPDNQKFDSVEEVLDLLDLRSIADQTIHSSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLVMDGVRKVANSGRTVVCTIHQPSTEVFMLFDSLLLLKRGGETVFFGELGENGRDLVGYLEAVPGVTPIQDGENPATWMLDAIGAGVGSSAGQLTDFASVFKSSATAGRMDQQLQSEGVGCPVPGEAAISFTSKRAASAWTQATLVSKRFLALYWRTPAYNATRTFIVIFIALLVGLAYLQVNYDSYQGINSGAGMIFMTTLFTGATSYHSVIPFMAEERPSFYRERASQTYNALWYFVGASIAEIPFVFSAMFIFTAIYFPMAGLSGAGAFFLYWIGISLHVLTMAYIGQLLAFASPTVEIAGIVSVLISTIFTQLIGFNPAYNAIPMAYRWLYEINPSRFSFSVVAAVAFGDCPSSDSEALSFDCCQKLSNLPVSLPSDPTIKQYFEQVFNVEHVEIGPNFLYMIVVVVIVRLLSLVALRFVNYQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH7</accession>
    <name>A0A8K1CRH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_012493</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRH7"/>
    <dbReference type="OrthoDB" id="266663at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032954">
        <property type="term" value="P:regulation of cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000132">
        <property type="entry name" value="Dual specificity protein phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000038">
        <property type="entry name" value="Tyrosine-protein phosphatase CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="15">
        <location>
            <begin position="177"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="16">
        <location>
            <begin position="260"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="345"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW67377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="417" mass="46738" checksum="E16556C26CFA0B5A" modified="2022-08-03" version="1">MANPVTIAGLEEAIEFLPGRLWYVPLKKAPPRVSGAHFFSIDDELVYWNFYLDFGPLNLGHTFVFADMLNKKLANAAKTGEKIFYYSSAQGQQRTNAVCILGCWAVLFQGMSAAKAFEPFERMRFPPFHDATPGVCTFQLTILDCLMGLEKALQSNYISPKTFDLHEYQHFERVENGDLTWVSPKFIAFAGPHNNYSRTPQGHVMLTPEHYIPYFKKRNVTLVVRLNEKQYDEKKFLSAGIDHLDLIYPDGTNAPMPVLMKFIEACEKTPGAVAVHCKAGLGRTGTCIGAYMMKHDHFTAHELIGWLRICRPGSVIGPQQQFMESIEAKMWQLNTFAKSNSKPHLLGKSSSTTVVGPPSPDRTMGRTLPLSSSTARNTGSLVATGKLDKTQGDKLNDQKYMRYSRNKASVPSGSMFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRL8</accession>
    <name>A0A8K1CRL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRL8"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="248"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42212" checksum="1A168D492D20E3E1" modified="2022-08-03" version="1">MTEPPTSADDGYATLIDTVFVIISICYTAQVLTPIPMTYLSEIAFPFDLCVKLASSTVLFIAHAIHWMLDVLDGHGWHSRGSGSPAEGFYDCHAFIDSIAWGSATAILWMEHRRSRPPSIFLRIFWITAWLEASFSLFSHQNVTRLDITTNSTLTGSLAALIYSCSAVLAISCFFPSTPVTSDLVVLPQVSTPSAYLRSWHRKPPLSGYYGSFGNFGGARGVQTSGSITTETYPTATELTTMLSHSATNIKATIPSSTTSIWGKKQFVSYKIVVQTEEDQWTLRREYNDFATVHDELPSTVRAACPLPEDQSKRKFLSWNARTKPMKVQLEQYLRRVLSFRCFEPHSSQALCDFLEMEYLDDASLRTLYGDVDWTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRU0</accession>
    <name>A0A8K1CRU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012279</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRU0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF12">
        <property type="entry name" value="ASPARTIC PROTEINASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035430374" description="Peptidase A1 domain-containing protein" evidence="9">
        <location>
            <begin position="18"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="31"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="506" mass="54854" checksum="F4F8017AFF879964" modified="2022-08-03" version="1">MRLLVVVMAAASTVVSASDKVPLTWTDRRTYTLEIKINDRNYTMQLGTLSSDVWLQCRSYVDSCSKTMCASVLAVESGHVCTTQSTASLEWSAVSVNESNFVISTQQLAVPGKDFPGLLSSAYLPAKDMVSNLPLVTSAAGVLGLGRGGSIAKSPKLLIEDFSLYLRGEAEKDASFLMVKGVDNEFLSSKGYKTRASIPVWAPSSSEFNAVNKSISWPVEIKAFAVGDKGPTTPHSKSSSQSSVGILSANSRGIEVPRAVANYFATHFLSVDVCAYVDNLEDPSYLSCPKDSVKDLPRLAIYIHDSVFYLEQEDYTHTDPSDDSRVVIDITEGVVSDENVWVLGAPFLRRFPSYFQSIAGAVTLYCVADSSCKAQATITNIASLEDAASTTQSDSTSESISPTETKSKSSFSMVAIGFAVAVGVGVVLVMAVFYMIKRRRKQQSQSQEAAVQDFYNRLRQNEVETMASERDLASQLGPRAQAQLPPVPEVADVAEMVTPPTSYRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSA6</accession>
    <name>A0A8K1CSA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSA6"/>
    <dbReference type="OrthoDB" id="94531at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006564">
        <property type="entry name" value="Znf_PMZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31973:SF187">
        <property type="entry name" value="MUTATOR TRANSPOSASE MUDRA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31973">
        <property type="entry name" value="POLYPROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00575">
        <property type="entry name" value="ZnF_PMZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="6">
        <location>
            <begin position="587"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="739" mass="82392" checksum="086B6A5F86A7B6CC" modified="2022-08-03" version="1">MATMTPTSTSTAVETDTTQDTTSSVAVSKRGVDARSNEVLAVENESAEVRALKTLKWKTGRELTAYVQDLALQHGKRALVATSGGSFKKFVCSSETRCPWLINAVCTRPRQRKTKTTALSGETDTRESEEDVAKRRYWYVSSAYLVHANCTGMAKPTVRQLKESSVLKQAVLTDAKVSSVQLMEQLKTQERLLCTKSMVYKAKVDMLDSLDTITTGSEDGTDPLAGSSVPVHPDLLRSTQLLPSYLSRLQELNPETLLQCTERDPASANHLWRAMMALRPERLYSTGKPPLVFGIDSVPVKPTPARPCTELICVGCDSNLSPMTLAVALVPEPNELHSLWFLQKLIDFGFPLQRAHVVFTDGRWPMTSACARAGVQCMLQDTRYVIQDVLKSMEHHFPTPASTRPGLASALDHLLRQDQVAAIWAAQNAGTEGEFYAALHGLETSGGSLSANAPTRTSGAFAAQHLRNIDPRRWALFPHMGSSRFYGWQTTRFSPSDQGRAISMSPPPQTQLPCEFFKMMALSLTQEMYQRHEFATQWAAEQRVVTVEAERMMQEEMKLVPMYNVAMSAPHIAFVWNPQGNAQIRQQRVDLQAKTCTCSVRQQFGIPCRHILSVLRKLNTLGQSFEYFDESYLVQNYVATHQGRRLELPLDESIHPDASWMPLRNMIPVIEPPVTQVRAIVPVISTVSTKASSTSATKKRRIRNRPEDARKRAMYKCRKCGIADGHNSLTCTNQRGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSC2</accession>
    <name>A0A8K1CSC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metalloendopeptidase</fullName>
            <ecNumber evidence="1">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSC2"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035489770" description="Metalloendopeptidase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="2">
        <location>
            <begin position="93"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="37330" checksum="1717CB1BEFBB1041" modified="2022-08-03" version="1">MRGYVVACVFLTQLGTVLSQSCSVDGFEFDGLAHYLVGEPYLPGSIYADCVQGKATCYRDDGVMDAVNAQVSCDEVHVKNQTHHRQLGITLKPVAAWPQRIVCVSGVDIFPNHTRKHLANAFREFAHKADIMFIDVNKCPSMFGKKTEVCNNCRQFVRMTRTKPGCQSTWGYSSSRQLSVNLPQSCADYKTVLHQLGHVVGLAHEHSHPHRQVIVLRENVVAGYTNAYKILGRSYQPFIYDPMSIMHYDNSYGALCIPLDLKLKYCDLTQTEADGCVVPTKKHCNPSYDLAFGRSTKLMPSDVATIMKLYAKEKSYAQSRSLRGSDVKQLWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSX6</accession>
    <name>A0A8K1CSX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001463</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSX6"/>
    <dbReference type="OrthoDB" id="2364732at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="648" mass="72344" checksum="6F8EF76EDE1F1CD3" modified="2022-08-03" version="1">MKLFCALVGASGSAFPVDIDESLTVGDLKEVIRGKKPRKITCDADELELYLAKRGDAWLTENEVRGISDTNGLKYLGAARAELDVVGLSEEDLRFEIDKHRVAAGYGPVNVLVVVPSNGTSMSVVGTNIEKFRTPLQFSTAEHEGGVPSTFRTYRSATVHAFFRLLFPPGGNFLPLIFVRAPPLSGKSAMFDLLYNHIVLSQPDALVARVSANFMPESTTFCQYFSSTYGCDFKAFCKLDYEKVVLIDEAQVTYDDDLLWLGYLKNTLEGKVHGLRFVLFSSYGSFDIYREDVRPGTPILVPPGNTFGLNAAPSKPGLQLTRVELDEMIHGSIGAAVGDLIWILCSGHIGIARAILRFLHGKFGSKKASIAPEDLEAELRSVRLLRYIRDSYRGIPTLDAFQRVIQGRQLADESKLKMSEVMSSVASGKIVLASDGERSPRSRLAVELLTRFGFLYEDYNKQLQFASNMHLKIWLHSNRSDPIGHMVSNISHDEFLVACITRMRSSQLQHFATGNTSNTLVARERQIQMELYNATTSCLPRDVLVTPEWRTSDEIGFVDLVIQGGDILWFWELLVNGDDAVSHSKRFKTGGKYYGSLTSHSRYVLIDFRQNKGVREQKLGFLYVSFVDSYSKAKIFGLHRDEITVELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT07</accession>
    <name>A0A8K1CT07_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT07"/>
    <dbReference type="OrthoDB" id="66204at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="284" mass="33478" checksum="07F2DFB10A313022" modified="2022-08-03" version="1">MTHETTAIQQRRDAEARKWWAERENEVEKELSATLHKRMEAQRAQIHAFKMEQSKWEHELQLRISKYAHDRKLLSEHNIELQEALTSMEEKYAKLEREMDRQAVHVLELEGQLVESELHAAQIKVLRAENEELRERVMRWESCHEAEIAAAVQRQEQTQNELFQGLERRIEELTKENANLRERRKRGSSHSNGTRDSSGDESSLRRSEDSHHQNEQDDEDDESRVAELERTVKHKDQTIVTLKALLERHEAISDEKTKLLQAKYDQVKAINIALQRKLLNSLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT77</accession>
    <name>A0A8K1CT77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RPGR-interacting protein 1 first C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005805</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RPGRIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT77"/>
    <dbReference type="OrthoDB" id="126486at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021656">
        <property type="entry name" value="C2-C2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031139">
        <property type="entry name" value="RPGRIP1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240:SF1">
        <property type="entry name" value="PROTEIN FANTOM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240">
        <property type="entry name" value="RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11618">
        <property type="entry name" value="C2-C2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPGR-interacting protein 1 first C2" evidence="8">
        <location>
            <begin position="576"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="299"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="499"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="670" mass="76281" checksum="2C9373AD3063AAB5" modified="2022-08-03" version="1">MRRTPRKPTGVRASAPTTLEEPATGRTLSWPERYEHVLEANHRLNARLSQLETAHRKSLTVVKYEPSLPNNDVYTKELVEENRQLLQRYRQLELRLAQTTSWTSPSSRRGIGGRQDTKRWQKEHRLPIRDRATQTDASESLRVETQEATCVDEAVSLAVEEAKREERDREVRALLTEWRARLVELETDLERLRQENELLRAESRVANEENQSRTSNRPDETTKIEQEELTHALSDRVRQLAVLEARFAHLQDKAKAKTALYQLSVSKVEELNAALFDANQKLLKQAEWLQAHDDKHLQVDVLEKEVHLLRSENAKLNDAVATLSSRPLASWDAKLQEKTLLIAKLEAEQRELETEVDKLRQDHRVITQTNQKLRERVKTLTSQLEVQAQELAKAKAENERLAMERQVAELQLRFYLSGEGGDEQFMEAVGRALKEIKAGEKGGKAASRSGNVLQEQKLERCASCKATSSASLQKERLERISEVTKLIQEDAGAQLQSLRVTHAAEIRALKLEAKQWEQRASDYLTQISALQHERSSELRQERINKARGQSSKTRASAVPDISERLSTSRPLATFSDENVLEITILNLSLDQTVSARGSTQLVLICDYYDFESQLSPVLTLSESKVAVDFSITYKLLLDVAFARSPLAMHATIELHELQLGSSQHVDESET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTI3</accession>
    <name>A0A8K1CTI3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTI3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456510" evidence="1">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="11464" checksum="0B5DEAB6A94C07C1" modified="2022-08-03" version="1">MVARTLALMVLVVFSLLFIVSGATPCKIADIDTIEKLLTSGSADKCLMTAPKVFNGVKDDEAKAVVGTICIDVCIDAVDKTLASGPNCTVGRVNKPQVYMAFCNDFGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUC3</accession>
    <name>A0A8K1CUC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUC3"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="131" mass="15303" checksum="1FD127E4F5DD3EA9" modified="2022-08-03" version="1">MSKMALKTDVLRVYRACLRSARKCPAWEQREMMKTYVRLKFRDQVQLKDETQIRRLLADAKEELEQMEYYHSVYAAKQREKEERDRQMASVVSTLSSEMQSAFVNALCPSCGTEYSPPQAKFCSNCGVKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUH5</accession>
    <name>A0A8K1CUH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUH5"/>
    <dbReference type="OrthoDB" id="5592979at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF10">
        <property type="entry name" value="GH13992P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="27151" checksum="2513EF5257C908D9" modified="2022-08-03" version="1">MNLFGRKSAPPVRAGPAATADTIRKLREQLDTLEKREMHIERKIQLQLDDAKKKSLAKDKKGAIFALKRKKMFEAEVEKLQGARMTLETQVMTLESAHVNMETFNALRAGANQMKAIHGQMSVDTVDNIMDDIQEEMATADEIGRAISQPVGSTLYDDDELEAELDDLLEMDELLKSPPAAVAASTPAAVAAAAAATPAAAAAAPPAPVRTPAAYNLPEVPTHPIDSNITVVGQADEDELEALRKLEASMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9T9</accession>
    <name>A0A8K1F9T9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010457</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9T9"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000045">
        <property type="entry name" value="ZFP69 zinc finger protein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="17106" checksum="008A7F487079481F" modified="2022-08-03" version="1">MTATTTTTIPMEDTSVDMATPPTTPTTEKPHQCASCEKAFKRLNDLQDHENTHTGAKPHECPREGCNSAFANRSNLKKHVTAIHQKEKPYQCPYDNCKKRFKHRNSLREHENWHMGIRSRKCDSCSEDFFYSKCLYRHKRAKHLSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAS4</accession>
    <name>A0A8K1FAS4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAS4"/>
    <dbReference type="OrthoDB" id="128103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462448" evidence="2">
        <location>
            <begin position="23"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="207" mass="23925" checksum="9DD76127B4BAF3B3" modified="2022-08-03" version="1">MTFRSVVSLALFATLALTSAFAQDANQPATAMDRDHDEQVRVAIGAHSHLNDATALANKNTVLHGNNVDITRSNVLAQKNDRVMIETEQMTEDPASDAVMPSGMSLTGERDPLARPMTSEDEPKDDQVQDQNKEDMDQDQDDMDDEDHEQLIARRRFFGHRYRFFYPGFRRGYYGWRYPLSYWNRFGRRFYPGRCPFNRVYGGFFYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBI4</accession>
    <name>A0A8K1FBI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBI4"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="8">
        <location>
            <begin position="15"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="167" mass="18645" checksum="03226AD0DB70EB33" modified="2022-08-03" version="1">MLTLFTTSSLHLDHGQYHTLLTSVFSHADMTHLLANMYALFVFGYEVSRILGPKRFLGLYLTSGVLSTWASVNEQKRSHRMKLNLGASGAVNSITAFSILLFPRSTLLFFGLIPIRAWVAGSLFIGRDLYSWLGRKNDGIGHFAHLCGAACGGLYYAHLRPVLRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBS9</accession>
    <name>A0A8K1FBS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBS9"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="234"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="340"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="49697" checksum="C37C0DC5CBC7591F" modified="2022-08-03" version="1">MHRVGSHYDGAAVYARRPKRRATGQWSWLHATACSSAIVASGAYMHSAITEYLDAISATTTTPDDGHATPQHDHDPKAIVTVSMVLSMLPWRWLGVYALLGLWLVALVVVQRLQLHAPLRRLAVATHGFFERFRGLTSRRRSRRKGSRSARRLFSTDLDIDEDDLLVVTSLSPARLESSNAERAWSQDGQQPRRRRDTSDILARTLGNNGRGAGIITRDPEADAQILLQPLEGASGGRHQSNQIIVDDPYVSRYHFQIRYDALEKEYYLQDLGSTTGTYIFLKPDVPKRLSVDDRVKLGDTEFEVVTIDVNLTTGSPFLRICFTEGPMRGVSQTIGKSSVSLGRRSSNALCIPDDTSISGRHSVITYLGDGFYITDLHSTNGTALRLSATGVKSARRYLLHGDVFGVGANRFRVEYSQELAIQQRQSGLTSCEHTTVEPSPTVTSQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCC0</accession>
    <name>A0A8K1FCC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MHYT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCC0"/>
    <dbReference type="OrthoDB" id="163408at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005330">
        <property type="entry name" value="MHYT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152:SF1">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03707">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50924">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="MHYT" evidence="3">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="MHYT" evidence="3">
        <location>
            <begin position="161"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="538" mass="58624" checksum="9040F8A919C9B1A0" modified="2022-08-03" version="1">MSITSMLNRDKVARKIKIIALLSHPWRIILGGLFAAIGVLGMHYLGMMGQRTHAVMTFHAGVVAASCIIAWVTAIAAFWIIFRVLTFWPYYNSLRVGSALVMGLAICGTHYTGMVAASYEYTEEDHIASTAFLINGTAAFLTATHGSVLVCFWMLSLSVVTDLRVDALSARSQNITGAAGAIQVMEQWRSQENKWKKLLLLGLSSLALGGCGIWSMHFTGMNALRIELNDSTMLEVNFEGGITILSFVFAVLGVFVGLKIASTDPFFLEIEHSRRKELLSKDLKKMKMENVVKKSQIGKQIKFIALFSRLWHIIAGGFFAALGVLGMHYLGMLAQRTNADIHMNPGIIALSVVIAFFTANAAFWILFRALTFWPNNEALRMGSALIMGVAVCGTHYSGMGAATYTYSEENYADRTAFLLKGASASTIASHGSLLLCFWLSTFAVVVSLRKEALSSISSKNHTTLNPNTEKSQGPRPPIKSKAGHSSRQSEQVGINGPNVSFVSSQHRPPMIKSMKSFKAVMPMNIPETNGSSNGPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCI2</accession>
    <name>A0A8K1FCI2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCI2"/>
    <dbReference type="OrthoDB" id="128235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="49026" checksum="0B2AC28AF3657E05" modified="2022-08-03" version="1">MRRLNGLISPTYTYYYWGASSMWRQAYETAANGGEASDQSGKSPVERFLDVVLHETKDAVAQEDARKTVWRELAQELLVPMNELQGVVFNKSPPDTRVRVLQLQVVCRLLFHSTALTKPKTKKKKSKAKTKKAAAKDPLSELRALLDRLALLLDAANPVSIGEGDEEHSPFHHFLIEVLEWRLGKVMPDVFRLLREEYELTEETEPTPAMLALQTAFAPKIALETKPETPDSSASILSALKDERPSKKRSLGEANQGFNQVLLPGQLQRSQSLVSRRQLFPGQNSKLARPSSASSLTGRSHSDPKRTELTRSASVSSTSSKTSLTSLAAATKKAKVSRTPSTGSGSVPLLLRNVDQKLMPRRTMTQLFSTAAPGAPAPSTRIPPKSTVQRSSASMTKGNVVMRTPDRPQRVSRQQQKRILIEASPPLRNPFAGRTRRPGPNLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD77</accession>
    <name>A0A8K1FD77_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD77"/>
    <dbReference type="OrthoDB" id="64875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039145">
        <property type="entry name" value="Ribosomal_mL40_metazoa/plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="157" mass="17621" checksum="1C856EDE7DC52FBF" modified="2022-08-03" version="1">MMMASTLVKRSAALSSQAGVASMVAEHVGAVRGFAAKKKAAKKGKKGGEDANFELMLRTVRGRYPDAEPFTEEEQQRFQEIGRRFNAMTSVRHNHFMRDLQTKIDLKWEAINALPVELQAEALEEDDAAIPEERGFPTWTPPIEGFYRYTGDGEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDJ5</accession>
    <name>A0A8K1FDJ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="5">PME-1</shortName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004559</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Demethylates proteins that have been reversibly carboxymethylated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDJ5"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="39"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="37902" checksum="4A5F627D16B07BB2" modified="2022-08-03" version="1">MSSSEEDAWRQYFDTKEDVTLDNGDAFRTYHAGSKGPHIVLLHGGGYSSMTWCLLVPMLKEHFTLHALDFRGHGMTQTSDDQDLSISTLVQDVVDVLARILPESEEGGQKTQTVIAGHSLGGAVAVRVAATEKVSSLVGVMVIDVVEGTAVASLDHMHRILSKRPSVFSSPEQAVHWALQSGTVRNAEAAAVSIPSQLTEGDHHGTYKWRTDLASSAPYWKDWFLGLSEQFLSLKAAKVLVLAGSDRLDTALMRGQMMGKFELRLLYGSGHAIQEDCPDQLAQALVDFCGRCARTVDLASIRIAANGGAAACAGPAVSSANDLLAQRLAKARAMVPPVMPAVMPSSIPKPPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFD0</accession>
    <name>A0A8K1FFD0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003467</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFD0"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="82" mass="9103" checksum="FC3BE2345442346C" modified="2022-08-03" version="1">MPRDLLHPTASEEAQKHKLKRLVQAPNSYFMDVKCPGCFNITTVFSHAQTVVLCGSCSVMLCQPTGGKARLTDGCQYRKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFV0</accession>
    <name>A0A8K1FFV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003103</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFV0"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="102"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="170" mass="17099" checksum="F32D5A77A83A2EC0" modified="2022-08-03" version="1">MLAQLVADVCPSSASFFGFMGVASALVFANLGAAYGTAKSGVGIASMGVMRPDLAMRNIIPVVMAGVLGIYGLIVAVIIQGSIDPPSGNSPKYGSYSGFAHLAAGLCCGLSGLAAGMAIGVVGDAGVRAVGQQEKLFVNMILILIFAEALGLYGLIVALILSQKKSECPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFX9</accession>
    <name>A0A8K1FFX9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFX9"/>
    <dbReference type="OrthoDB" id="107250at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="62318" checksum="80C0D3E579B55FB1" modified="2022-08-03" version="1">MDRFDQRVRSLRKRLALDFQPLRSTLARGLDVLVDPEAAVLCTATVEALCDALFNVVVKNLHDDAASSVAPLDTKVTIYHIQVALRGHDDLAQVLSHVESASVVLECFMDDATSKALYQRNLIGTRQAKHLRAADENEEELLRLHERMRSEWQRREDDPFTDVDFATVLKCVHPAFTLAYNATMLLSALVRELLNEMCDRANIDAVQRRVPPELYPEDLYAPLTDVFFSVGETGKLMEKTASECLERFRLQSRHSKTLSLRFRVYLGANGNAVQALRSSPFHTLGNVARDAPFSQLLPQMCKKCHLDAPSTVVGIYRGHQLEPSTTPGMLSMPMGAVIFLVSKKWWDHTRRNEARRGLMSSLRPQDALVKSLVESSESRVKKEFQAAPVEATPFGFLGATASSASVLREKPLGQSHSLSRLEKKSSPARPRQRDEEEDNGNEDDSDDDEDSLSALVAGVGRRTESISVDARGLVQTLTTRSTQLLATLDEAWLGFAGLSGGLRTLQDALSRLPDDGDALEQELRTRLAQTTALARQTATAQTLMTQLLDDTRRLRRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG77</accession>
    <name>A0A8K1FG77_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG77"/>
    <dbReference type="OrthoDB" id="74035at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="251"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="432" mass="49447" checksum="E0FEECDAA442D74F" modified="2022-08-03" version="1">MRLVPTRGVKQLVGGDMEDWNYGSDRSREEQHQQTPLDGDDDELAQENHVLRQENARLQQRLVEKMRGNSKILVSGGQFRSSVHPQKQAPAVLASSVGVHTTCTSCSSLRTSLKQLRQDHMHVQERTREYAQQLQRLETTQQAFEEAVDGRDREIYALESEIETQSARQGTLAAQIESLERNVMHLEALNESLTREIADFKAAKTLECAHKSVQCDVSESSESSREENLPFTDSDAVTRVENELLAVRSINQALIQETLALQKNIQLLENDKSALHEETRGWKTRSETVESQLSELENTRRAMESTMIAITQSRDELRQENEALQANQQRLQDALSARDQQLSRLARRMNESESESHRLRDTIEEKELHVVQMRKEVAEMATTLMDKTSNHATLTEELRCAITVSEEQATSMQKLQYELCRVQGEWQEKLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGH6</accession>
    <name>A0A8K1FGH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein O-GlcNAc transferase</fullName>
            <ecNumber evidence="3">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGH6"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000181">
        <property type="entry name" value="probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000070">
        <property type="entry name" value="probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:002605">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13431">
        <property type="entry name" value="TPR_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 8" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="209"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="277"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="345"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="447"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="9">
        <location>
            <begin position="494"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="9">
        <location>
            <begin position="738"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="965" mass="109004" checksum="036BF5D0B4B08FCE" modified="2022-08-03" version="1">MASYARNRVAATPSPLNAANAPTAHATDPMLMDASTQRFTYLYNMAHQQYSMGFYEEALRLCEQLYETDAYRTENLLLLGALHFQLGNYSECIFYNQQCIRVDPNFAEAYGNLGNALKEIGDIMGAIQFYLKAIRLHPRFSDAYNNLANSYMQIGQISDAIETYKMALLLDPSLVDAHSNLGNLYKAQGRYEDAKMCYTEAIRVKPTFAIAWSNLAGVYKDVGHVELAIDHYHEAIRLAPDFADAHSNLGNVFKENGRVQEAIEAYKRAIAIRPEFAIAHGNLASAYYDAGQIDLAVHTFRHAIQLEPNFPDAYNNLGNALREMGQLEQAINCYRTALRLKPDHPHAYNNLGNALKDKGMVKEAIHCYATAARLMPQFAAAHSNLGSVLKEQGKLDQALAHYQEAITIDPNFADAYSNMGNVFKDLNRLEEAIQCYSTAIRLKPHFPDAYSNLASAYKDGGRIDDAITCYRKALSLRPNFPDAFANYFHSMLFICDWQSREGDLKKLVQFLDAQLAMDNVLPSVQPFHALVYPLSMQCFLDISRRYAERAKLNVSLVEAPSLRYKSKKSQERLRIGYVSSDLGNHPLAHLMQSVFGFHDKKQFEVFCYSTTPDDGSIWRRKIMGEVEHFKDVSMMNNGDAAKLIHADGIHILVNLNGYTKGARNEIFALKPAPIQVSYMGFCGTLGADYVQYMIGDAVVVPPEHRRYFSEKIINMPHSYFVNDHKQSARDVLDVEKCPSRAHYGVPEDKFVFCNFNQVYKIDPATFRTWMNVLKRVPNSILWLLRFPPLAEANLRAEARAQGVKDNRLHFTDVAPKDEHLKRGYLADLFLDTPECNAHTTGCDILWGGTPMVTMPKDRMASRVASSLLKAADLSDLITTTLDEYEELAVALASDKDKLWEVRCRLEDGRLTCPLFDTARWVQNMEAGLRMAWDRHEAGLEPDHIDIPDVQDRAAARPDARQQTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGV4</accession>
    <name>A0A8K1FGV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009549</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGV4"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="108"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="482" mass="53048" checksum="C718D67EFBFC846C" modified="2022-08-03" version="1">MAHDAENVGWLPALMCYVQLAILMAFGHTREFLGGIFGTSTPTEKTKRGYARLLVAFEDFYIKRIYHRFEHAFNRPVTGTPGAYIDVVERNAKYGDKNFLESTGNVRHCLNLGSYNYLGFADDWMNTCSKDVLDAVENFGLASSNSAMEFGTTTVHEELEKAVAKYVGKPAAIVYNMGYATNSTSIPALMGKGSLIISDSLNHNSIVNGARASGATVATFRHNDPQHLDRVLRSKIVDGHPHTRRAWTKILVMVEGIYSMEGEIVDLRAIVNVAKKYKAYIYVDEAHSIGALGKTGRGVCEYCNVDPSEIDILMGTFTKSFGAMGGYVAASEEIISFMRGSSAGANYSTSLSPVIATQVLTALRIIDTTELGKQKIASLRENSNYFRQKLNEMGLVTLGDFDSPVIPVMIYSMSKIGEFSHECFKRNLAVVTVGYPATPLLLARVRFCVSAAHTRADIDDALKKIEEVATICHVRFNKSWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH18</accession>
    <name>A0A8K1FH18_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_002346</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH18"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF17">
        <property type="entry name" value="RE54080P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="55"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="12">
        <location>
            <begin position="342"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="225"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW63405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="427" mass="46935" checksum="3A7534A7FEECC94D" modified="2022-08-03" version="1">MTNHTNVGRPEDHVVTPPTPQDVNYIAISEEVASPDQEAPSKPVPDESQLAVRKLILVTVIALTFMLMEFIGGYIAGSLAVISDAVHMLTDVLGFAIALTAIWIGRKPPSDRHSFGFHRVEVVGALVSIMVIWVLTGILFYSAVLRFQEFLEDDAEQVVDGKTMFIIALIGLIMNVVMMKVLGGDGHGHSHGIGGHDHSHDHSHGEEGHGHSHGSSHSRGHGHAHNHDHDSHSHNHDHEHHSDHEHLDAEATQDEAKPKKKSWCGLWESKFENLNIQAAYLHVLGDLLQSVGVTIAGAIIWWKPSWQLADPIMTFVFSLLVVGTTINTVKESLHILLEGTPRKFQYTKVERGLRSCPEVVAVHDLHIWSLSSNKPALAVHLVSSNPEVSLAAAQQYLIGEGITHTTIQIEHPATQYPQKCSDEGRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH64</accession>
    <name>A0A8K1FH64_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH64"/>
    <dbReference type="OrthoDB" id="164959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="576" mass="62230" checksum="DFEE57420F077B7A" modified="2022-08-03" version="1">MWMQQSMESASFSNSANLHQRNRFAGSGSASYSGGGMGANNANGDWKSKILEGGQWLGGKVIEYGGKIARGGSHDSIPDHMAHVPRNDGRANWMADIRNSSSSYSNGGSYAGGGSGGTYQNDFATERPKAYSDSTYSSSRSAFSNTNTNSTPALQPYRDSVKDSHRSKKSVKTSKKSSKKKSKKHSKRRGGHSSSDSEDSDSASDSDMSSPEENSASDASSDAENNRRRAKTKRKSSKKRRDSFSSEEDTLEAKPKPVKTVKPEKAPADYSFSFDPAKLPAPPADNDDFSKKSKSKVTKKAGSKSRGRRQSMESTASESSDKENTERTKKTKGGKTKVALKNKSAAKSNQDSVDLLGVDFMDAPVATTNTAPMASQAFSAPSQPLNVFDQPLDPLQALAGLNFNTTYTPPAPAVDTASTLSASSSTNSMAGPTADSQVLKKLLPDNDIIDLDSLASDKKKKSKDGAAAERKTLNELQSETKHQHQQTTHVMGMYANPQMGAGMAHPMQMGAMQNPMQMQMQMQHMQMNQMQMNQMNNMMQFQGQQGYANPPYAAQQGYGAQTQQQNTMNNFAFGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHG8</accession>
    <name>A0A8K1FHG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHG8"/>
    <dbReference type="OrthoDB" id="190958at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="23953" checksum="9651F2AF84B10290" modified="2022-08-03" version="1">MANATDPQAQSVHGVNPQHLIEKIMRNRIYSCVYWKEQCFGLTTETLVDKAIELDHFGGTFGGNQQPTPFLCLLLKMLQLQPETEIVQEFIQNGEYKYVTLLGAVYLRLVGKPLEVYQLLEPLYSDYRKIRKRNVMGWEISHVDEIVDSLLREEFYIDLSLPRLIDREYFEKNGSLPPRRSVLEDELEASDDDDDDDDSDEDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHL6</accession>
    <name>A0A8K1FHL6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHL6"/>
    <dbReference type="OrthoDB" id="117447at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="41085" checksum="B4A4E81821C5B627" modified="2022-08-03" version="1">MMLETDAAMGADGPRGPVKNPSRERMQAELRYLRVLVVELETERDQLMASVASPDVNALVQASHTGVGDEYERRKQAEELNVRLREQMDEHIAVIERLKELIDQRADSDVDTDMTTDGEESQDSRHLRFENGLFREFLNDVHVGYRMTGSIVDTVDWDGESHHRSWRVDTRMGRCNGRPQRVLEIQKQFKNPVSSFVHGEGDLKSWRYLAQYFQSSPLSVDELIIQEDMMAIRYRRVYSYRGRDIRVSISWVIERFVEANREVRVWRIKVVGLEGVDGENAMIDKTAPFVDVVGWLVVQPAEQGVVTRICAHLVPGFLCSEDAETAQDESSPHLGDLVSYVLQSLQMDISHANDQLAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHP9</accession>
    <name>A0A8K1FHP9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHP9"/>
    <dbReference type="OrthoDB" id="78940at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="52631" checksum="C08D20C9B0B72EF5" modified="2022-08-03" version="1">MSTSTEQRLVNALEAAVCTIRMLSPSVVPGWVPPAPVPTTCQICMDDFEPMSTPLVTKLCHDKCPAVLCPSCVAEHVRIAVEDAFPGVLPKVRCPICLTFMNKSKWLAYTSSEVLAAYKSVCQRACTYQTPCCHNANYTQLPVGMSEHNKYGALAPLKLVPSLKAKFPQLRALTKQFCNHKLPSKTLIRFIEDEFGAKTSLETQHLLVEHMYTRILDEERRATLLLAYHAKYKLLKTRCCNRIVCFNCKRGTLPSHTVCDKLSIKSDCIVECRSCRVTIVKVDGCDVLRCWCGFIMNWPEEVQIRNQNQRGLIPVDISDTELYSAWSKWKSPLHLNVHSDLATLLHTKRVRHIDQMLLRYTPRLRRTVQHYAQKRRKSKLIAQLQEHMHAKELNVLTSKLKVTQVLEQMRRWCCQIHWQLVQNAIQTKFFWELYYDYHEEELDAIKDEEQAILLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX0</accession>
    <name>A0A8K1FHX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calx-beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="188207at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220:SF1">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX COMPONENT C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="repeat" description="FG-GAP" evidence="5">
        <location>
            <begin position="2140"/>
            <end position="2191"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="5">
        <location>
            <begin position="2195"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="6">
        <location>
            <begin position="3552"/>
            <end position="3673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3703" mass="397552" checksum="27AF7E5E51358DB7" modified="2022-08-03" version="1">MFTSIRSYAVDAKQLIVLVQPITSVAGEPFALQPVVALTDDDGNILTTENMGTVRAQIGVNPARFASVQPATNSFPIENGIAKCAGLYINLVSSGYTIMFVSLYHGVRAETAPFDIITGSRYKLAIMADISTAFGGTAFRPQPAVGVVDRGGNLVESLNEGTVRLEILKNPVGGTLLPARNLNVSIGGGMGTFQGLYIDVAGSPYYLRYTTDLVLEGGSIVDTNPFTVAEGLCNNLVLAKTPKEATGGKAFSIQPVAKLIDAGGNLLEADSSSIVRVAIASNPSGGTLSPSSLLKARVEKGIAIFRGLRIDKAGEDYTLTFTLFTKIAGRNDWLETSIEKLSPSFNVTVGMPVELFLKQNLSDGVLDGQPNEVQPILALRDSGGNVVSSLVTGTVAASMVPSAGIASSIVVDTSSAPMLIVLEVRALPTPGYLTPYGVGMRIYVQVTFSDEVIVTGLPILTLVSSSTGGPNGVAECVTINTWTDKLLFQYYTTATDAATDMDYVSTSALSLNGGSILDRNGRTPVLTLPAVGSANSLAGTSDVSIDTTPPVIVSVSCTDPGDGEFGFGEEIYLKVLYSTPVTVYGAPVLPVALNVIGNGAARRDANFSSGNNTDTLVFLYVVQSGDATAVGVPLDVTSTIILAAGMYIKRYSTRPTTDVVTTMATVPKNLASMNAMTIDTAIPIVDPSIGVTSTAINGVYMPGDVIDIVVTFTKAVKVDGFPRVYMESGSIKRPAGYKSGSGTTRLVFSYTVAAYDSHSATGNTFLNYRDGTALDLNSGSIRRYTARGTQAAGADVSLAATTLNLKSLKDNAQILLDGQQAKVLALSIVSTPSNTVSRGDVVRISISYSSQVTVDTSNGKPSLALGVGDNNRQAIYVSGSGSQALAFDYTVQLGDHAALGMDYRTTTSLALNGARILKMSANPTMDADLTLPEPTLSLANPVVVVDPLAGFQPTVESLTVDVPVGEYGSNQVMSFTVKFSDEVVVDGQPMLKVNTNFLVPYVTGTATRSLVFMYIVRDGDATTDLNKFNDDAIVCDPPACSIMNYNGELAVLSLATTDLQPRGIVIDTHPPVVVDVYAITPAATVNGGSFVVGDVIQIIVEMSLDVFIDPPTTAYPEKAPLLILNTHPFGRQVLCVGFFNEDHKKMLFEYTVEDGDVADDLKYLDTDSLTLNNGQCAIKRFSTTPTTDAILTLPTPYPLGQAQNQVLNVNTLKIPTVLGVTASTPDGTYRCGDRIEIVVSFSQHVVVEGKPFMWLDLGVNARKAMYTSGSGTMTLKFVYTIEENDYSVDLEYIDHHSLDASAAEDSILHYSTKPTTLANLDLPYPYTQNSLSFNKNFLINGRKPTITEVKFLSADGVYAVNDKVVIEMTFSSCVSVVPAPTTGAMPQMKFQPIPPGSTVLITRYARYVSGSPGNKLRFEYTVKTGDTSKKLDYADAQSMVWNGAKILTCTTSIVANPPVQLVETHLNPPGGRLLGATSKPIIFGSVAFTDLLVDHLGFNYEVKYRTDVGLATLEAANYFDVLYSAAYGLRSTPYASGDRLGSSVDVDGDTLVMGAPGAKEPIPAVQIVSVIGDSKDYVDEIQVLETIATQRPAIQEITTSAAPGETVGGWFFLKMGSIGPTRRLYYNFDEAQLRVALELDLGFGLETIRVTRRENTYCGCDNAYVWTVTFMYVEGTLPTLTTTSMLTGRLASVGDGRGANQARILVESTAISGFFTLQLGSLVTRNVKYNAAEDELSTILSQDLKLPVRRVMRSLPTPVGGYTWSITFAASDQIYDVPDLVPQNVGLGGFQARCLARTARDGLGRVSGAFRLRFRNDLFPNDETDDIPVSASDLQVEQALEKLVSINDVRVVRSSSMNVYGGYAWTVTFIQVNTRSDYGPVADTSGNLPAMVARTTATINNKIVQLLKGTNARVSIQFGGYSLPPLTDGMTHWGLPGTNAGQAAIFIRAENDWKQQGGTLVGGDTRAEDRFGASVSIKGNQVLVGAPAAAIFGDFEIQNLLCDADGGYFKVVYRGQASDPIPFNADKETLRLAVVTIMNVGFTDVEISTTFPTVCRAGNPIEISIVLRSGDHGDRTGNILDLQVDGSHLTKTNGVGSVAVAEYRAGTYRSDGVDAKGIQIGAAYLFKRDPVTTTWSQQLKFTPPSSTIFDMREFGYAVAIFDTFAVIGAPGAYDNQGRVYVYQFNAITATWSLFQVLSAAPYDITSGDRFGESVAISGNPLATVTIVIGAPGYATASGAVFVYDVFNGKFQNRQFILQITPELKIGDRFGCAVDLDMATTYTLVVGANRNAYKNGRDTGIALVFVRRSATDTFFNLQQVLFGSDSRTGDRFGSSVAISRHTLLVGAHEDYKGAKTTRKSVQAVTTTVVGSSSAKLTGGTFVLSLKLADDIPNVINGTVISTLTKIKSRAIAYNVDAASLRAQLEKDFSFFGKILVTRDGPSATTSGYTWYITFAGATSDVPLLVSDSRNLVVTGGPGGRALTSVRWVVRSAPVLRGNTYAFTRTSAGKWIEQASLYPREKQYSSWFGSSVAIDQRTAIVGAPNLDTYESGINSGGGFVYDLGFLAVGFSAKSYTVVEGNDLDVTVQRCSRNNGFCAMDTSGSPRQFINYDTGDAFSDLRSENFVYTPPHIGPYRKLAQLEAVPSDPNAFFAPFTAGQEPYPLTPRGRWLVFDQIGTANSRNQFYGSSDPRSLWIDAKFDYAGVSDYTTATGEMFFDVDIVFQTFRVSTTSDFVVEDPDETVPLRLSLPGVWPSYEGNLWATLTIKDNGDGGSGTRSYLDFLTAGQASRFHQSDSKFGAAVSVYSDGNVAVIGAPMEKQVLPNRDAPVQCGAVYFYVRRSGFWEFDAKIIPGECENGLQYGMSVSIDGILGTIRAIVGAPGAAAAYIYRRQGTTWLQEVRLSDPSGAVTSPTHAFGGQRAVGISGDVAVVGAAGAERIFIYHRTMAGWEFITTMFCSDRVVTQILQQSMSQTYRFGHSVAVYRRTIAVGAPYADAGAFTAAQYHDRSFDRKYFGKGAAYIFHLQAQEQTISLRTDDPLTAGTFQLTTTTRGVTGTTVTLSYGATALGMKAALQELSTIRLVEVTRKGSIEQGYTWSVTFIGDILSVPVLTAQWKDHGCADCDTFSSSFKADPDNQIVVSEVTPIGIWREQTRLTAPDGNPGDQFGSSIAISGEQVIVGAEGSGALITTTWDFETGDLTGWLTTGTAFDNQPTYGDNSYARINSYKIRLPNMEAPGQRALHEGRYWVGTFESRRGASKVVAQVSACAFASDALCNLPDYKLPGPEAAGTFQGDGPQGTMTSQAFTVRGPWLSFRLGGGCDIRLIYVELLIDGRSALRATGKCTESMEVVHWDLKPYVNKSAQIRVVDASSNDLWGHINFDDVQFSWDVAQATTPRAGVAYAFRRKAPTSQDPCIGINRWQCNWEFQARLIASDKRTEDFFGYDVAIDDSTGVAVITAPGQPALDANNSLILDEHELYLLEGVGSVYVFKRADEVRDGKGVLLSPPKWAPKETAKLQFPKKQARAQFGFSVALDRTTLFVGAPLLSTTLLKPKAGQVFAYDAGFATVRFTTSVFACVEGNPDGVVSLTIARATTDLTQPLTIGYATEDVNAYAIDQLKYAACLKIPITQRRDCFDYVQTAGEITFAAGEMSKQIIIPILDDTCYEAKEESFIVRLNVPGGEALIGEQYVAQVRIDDDDFAYSDDPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIS3</accession>
    <name>A0A8K1FIS3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007952</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIS3"/>
    <dbReference type="OrthoDB" id="72253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057">
        <property type="entry name" value="AFADIN/ALPHA-ACTININ-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057:SF1">
        <property type="entry name" value="AFADIN_ALPHA-ACTININ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="167"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="302"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="600" mass="68681" checksum="ABDFB5474F421BB6" modified="2022-08-03" version="1">MTNMETLPPRTRRPGELVRTSSVLDHDATFQPSKRPRLSAGDALEVENEPPTSSVSLIERLMEEVSYCTWRLSREQPMDVNEKYLNEQLASAAIVGGEKQTQREREMTFENARVEFSTLWTLFQAGNDASKQEKTEKLMRDAMDVVSWLLVLRQQEMTRQHATMDALRVMEKGVERKQNQIQQLHENVEILKQQMAQQENMFHGREQALVKERKVLQNDKKQLEVLCAKLQGQESAYKAQLRRKDAEYERLKKSLQDAVQRSIKDQRGMTIGKPLNDARDRKQVAAHRVVQTHETLMTKRLINNLEQKRDELISENDKLATNFETLQRQVESISAQYKKAVQLFLAQRGNENNTEETAALARMPIDDFTPAPLKLGVKTNVPAYISQTLESLVTKVQVFERAMQAEIDYKARNPSEDLIAALKEKLEDAHAIIAEQDRLLQASLCTSVTALTMNDHDLGKGKSHGVGVDKENVDINSGKLNPTWRAPALSSSNRHPGMRRKRVETVIMEQWAEELEAEWQVVRRKQKHLDNERTLLQTEGIKLDEDRIAFELRNFAHFFGSDASKEPEEIDMDGFDVPTTPRTAAYLQSIGIRATRAPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIV0</accession>
    <name>A0A8K1FIV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013590</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIV0"/>
    <dbReference type="OrthoDB" id="121753at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14312">
        <property type="entry name" value="UBA_II_E2_UBC27_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000037">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041974">
        <property type="entry name" value="UBC27_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="11">
        <location>
            <begin position="589"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="10">
        <location>
            <begin position="742"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="784" mass="88858" checksum="E66712F46AB5B8B9" modified="2022-08-03" version="1">MDISGPPRPATFACIIVNHEPHAVLYVHVNLIRSVYQVMEAIKSHLGAAWEDRIAGEMDLYFAKHGDEWLSLSDPDVKALLEQGETTEGIAQLLGGSPLKTTLRVTTVLPESSLKTMADDQLHILVKLRPPVQEESFVPRPLPTINYEWKEPQPLISSASVGSTWDFQSPFDVNEISKTMRKHYRAWKEKRDDKSCHPIFTCIDGPGTGKSRLLDEFPRMLQEELVYPPNCEDAASMKKMLKKALVFKISFSREEVYWSVTSTVGCRMIFQLQDQLPWDIFSRFTSPRMTPDHVLWFLAQELEIPRDELCVILCVDDLQCLAKSTHDTVAARGEVCDDVNVPFHDTMRTLARLVNGAEYWVTVICSSTSFTDIYEYDILMRQWRVEVATRPLAHPTANGKRVFVSFSMEDAHLMEVLVDDMGGLPCALIELYQVLDTKSKTHGVQMFSFDAVYDWIVQAFRAKYPMNATQLASVRLAFLAVLRCESVTHLSHFGDLSLDKVLACGLMRVQNDCLMCPYVLYMLLDSEASPWEFLEQYLPRKERSDRSPWTTWEDFNIKFRVLKSLAWGEINDPYLRWGNLHEGARCGDYASGRVRKELEECQKDTALSGVFATARGDEATLDQLQGTIKGPEGTPYEGGVFNIEIVIPQQYPFEPPKMRFETKIWHPNISSQTGAICLDILKDQWSPALTIKTALLSIQALLSAAEPTDPQDAEVARMYMNDPEQFQNTARFWTETYAKERASDDDAAVSRLTDMGFPADQAKRALAECNGDENSAVEKLLSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJF6</accession>
    <name>A0A8K1FJF6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJF6"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035439012" description="AB hydrolase-1 domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="70626" checksum="924FBC639F969F1D" modified="2022-08-03" version="1">MSRRLCILLAAALALTPISSGAVEINGWYQCSASTLWDAPDEPDMNYYMETKRRRAAPSAHYPQAKTNGDAPKFVLSEKRQWRIPFLQQSMEFSKSQSAHSRRRFKDGKEAAPVYECAEFRVPLCYEGICNSTSFIDVFVKRVLPMNSLSEGESKKALWVLQGGPGASSTAMEDLLETMHTELDGKVAIYTMDHRGTARSNRLECQAAQAQTPGSPGGTVITVEEVPACIDDILFQIENQTAAFSVTSAAMDLRTIIEQSSDEDEDVYVYGLSYGTYLVERLIHFAPKRVRGYVIDGIVSEAGAKIEDRSTYSNWDHDVGVVAERFLGYCAADSYCKSKFPETDNLATFVKDLYQELDEAAQDPGQNECADVLQAAGRRPSYFLRSLFGDYLMSQTWRIVIPAIIFRAARCSSEDVDALQHLVDDLSGPPNDNVDVDDLLFTSEPLYNLIVFSEMWETPTPSKTTLMEWYENATMASDNYYSLPYYCLFTGSREEACKELKHLPPSQPMMYERDQYWNVTAKLPVGSSALLMSGGLDVQTRRMYGNLEYELLEGDHMLVHFDYAGHCTTFTTLTRSGVATCGVQILASYVREDGVLLNVDTSCIDDTFALDFHGDSRLAEELFGRRNLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJQ6</accession>
    <name>A0A8K1FJQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJQ6"/>
    <dbReference type="OrthoDB" id="206948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057626">
        <property type="entry name" value="S-S_Temptin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055313">
        <property type="entry name" value="Temptin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737:SF2">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24784">
        <property type="entry name" value="Temptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421802" description="Calmodulin" evidence="3">
        <location>
            <begin position="21"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="467"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="521"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="565"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="601"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="635" mass="70745" checksum="2E4D505E0EEB6E6C" modified="2022-08-03" version="1">MIAMTQRVLLLLGFIGTVQARQEFVARIPNGDFIGEDFSLGHTEADEYGEVELNDFGKAFAAAGHKWTPALCFGDADGDGQSNGAELGDPCCLWQEGAVPLITEVMSHPGDPNSHLGPVDVAIRQAVCRAVSRLSLDGSDDSLDDSASNDDDASDSDSDSDSGSSSRNVTSHSDSDDGSNEASDSTIETPAPSSATTVWTRPAAHHLIVPLSFLLFSMPQLSSGSKDASPQHRSPVQDELEALYQLFRLTGGEKGAWRVSIGWDKLAHAVEQSADALMLRGSMEMLVQLHGVVWERNHVVSIDLSDNGLHGRLPRALVRLRYLKLLKLRQNPDLRGELPFDLFQMPRLRYGYLDGTRIENVLPLRLAHSFQITQLYSAKPGKRASAAATVTFQTGTGGQATFWWADMTESELLSVHTSLKARHEKPQTVVREVKVSASNATGPERVEAAIKLQRIYRARIERTKFRAFLRSLFEKHYDTTTGYEYFVDKRTGESMWERPKHIGHTPRKTADGDENNNEDIWQVFDDGHGNTYYWNRITGESTWEPPVFMTRIYQELRSRYGADKTDEERFALFFQDIDKDSTGSIDRDEFARLCGDLAMAMSPVEITTVFAELDTSGDGELNREELIAWLTRHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLI7</accession>
    <name>A0A8K1FLI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLI7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="355"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47990" checksum="D2D096F30EE17801" modified="2022-08-03" version="1">MNETTKRALSQAAEDGDLDAVRAFFTLPSGAEAIARSNADHRLAREMAVAANTPPPQLHFESRHAHDYWYLYFPPKEIWERETIFKRIIKYRQFHVLEWFISRDACAVVGDTMCGLIYSVLTSAVASAKQSDAETVLEMILESDLCMEVLPPAELKFALEHLAGQAIRKKRADLLRLAVAYGVDVNSHYDGKSLLFYAAHCGHAESIRELARSGVFGVQYMYPISINNNDAALSLIELGLDLQGVPGFEYSSLQKAMLGRDLELAELLLTHGYPDVNARGLTANSALILAVDSKNYSPISMDIVPLLLSYGADVRHRGVDGRTAIHAAARFFVETKALAYLLAHDPDSINIPDDKGRTPLHVFLTSSSTSFSFADADLLLSYGADPYVNDHEGESAYDELMRSKTWRAYMKSRPQYFPPQGNDESGTGENKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM10</accession>
    <name>A0A8K1FM10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM10"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044198">
        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="6">
        <location>
            <begin position="299"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="352" mass="38765" checksum="8ADF3B32FDDCD3C2" modified="2022-08-03" version="1">MAPVAAEEQPKVVEETVEVEAETTALTTSGRVRRTIQKFGFDEAKDGDEEEEFQPPVGNGVKVSELEVVAERIAALNKKDAEVLKSLYSIMYGRRFQLKNIKAIKEHILEFTGIPDADDKTQAQLMQKIGRWKRTFLVEIIDLLGVNRSKKSFDEENKVGDKEGLMQRLIDWLLEPKETGAKPKAARKKTKAKTTTAKKSPKAAAGTKRKSPSSAKTPAKKAKTAKAKKSAPEEEESTESEPEEESDDDKGNDSSSDFDEAKSGSNNKSKRKATSKQSKQDDEDSEPDNNESEAKTASSGLNAAVREKVKSIIASGNAEELTLKKIVRQVSEELGEDFSSQKAAIKDFITQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM95</accession>
    <name>A0A8K1FM95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metalloendopeptidase</fullName>
            <ecNumber evidence="1">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM95"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="2">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="188" mass="21073" checksum="112D2B15FDA8DF6A" modified="2022-08-03" version="1">MGVCNGCSIRVKITNNEPGCFAKLGYRTDVDRQLNLNKETNQGARECTILHELGHVLGLSHEHQHPDRSVVVLRPVSPGKERSYWKLTGQRKTPYDPTSIMHYDKKLCIPKPQPQGQKRFCDIHESPPEVDCIIPEEAHCATGIAAPKKLSGGDVKGLQQLYPNLLPEPPQEITPDNFAKFMKLDVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMP7</accession>
    <name>A0A8K1FMP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMP7"/>
    <dbReference type="OrthoDB" id="201621at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16443">
        <property type="entry name" value="LplA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053264">
        <property type="entry name" value="Lipoate-ligase_2_inactive"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43506">
        <property type="entry name" value="BIOTIN/LIPOATE A/B PROTEIN LIGASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43506:SF1">
        <property type="entry name" value="BPL_LPL CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="30"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="251" mass="29661" checksum="62C20E9BB2A8477E" modified="2022-08-03" version="1">MTLLTKPRLGFVRLRTSIQEQLRLEEALFRVEKQRNWFVYNEESTPTTIVMGISGKPEQLLHLDQVKRDGIPVLKRFSGGGTVIVDHHTIFTTFICNVESFPHVAPYPREIMAWSSTFFSPFFNRLCVDQSLKFALREDDYVFNDRKFGGNAQSISKDRWLHHTSFLWDFDSKNMEYLTNPARQPAYRQKRSHTEFLCTLKDVLNVENRKRLVEEFRSELTEHFEVEDVDAEILKPLLETEHRRSTRFLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMW9</accession>
    <name>A0A8K1FMW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynein light chain Tctex-type 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMW9"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21455">
        <property type="entry name" value="DLC-like_DYNLT1_DYNLT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12871" checksum="0B5DAC553F626DC3" modified="2022-08-03" version="1">MDTAESEFSQEDVLPIAKTAIESALKDTVYNRKKVLDWSNTLVATVLTGLQNLNKPFKYAVTCMIMQKTGAGMSTAASCLWDPTLDGYCTVLWENSTIYCIVTVYGAAISPSAGKHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNJ0</accession>
    <name>A0A8K1FNJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100219at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="15"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1423" mass="160169" checksum="D3B0180FDE0F2309" modified="2022-08-03" version="1">MASSSSPSFPSGIYRKYKRATEFFLDWLVRVRSHSGGGGGRRSKAGDRVTLEVLHRIVDKIQGEGVATLSPKLLHELPRALVACQCAITLREHVAQYFQEPTATSSGDANLSHEHFVRRLKTWYATLSGVLVKNRTQAALSQAETADVKSGKYTNYYEVLSVPDEFFPDADTIVVEPEGNAGEAPLTEEERKKLFDYAFAQDLDMEFACFLLELEELLKSVYNAYVDVKLQRKTLVEATVVAKMAIQFADAVIAKLQLRFPSIRLAQDVGTLLQDRLASSATMKLFDGIMTEFEQAAPLKQPPRFVPGSFLAEYIWAVSALMTFTSAIPSDPRQTLILRDGFFGENYDEERTPDYMLPLPQAPSAFLMQQLPLLFNTILANRVAGVRQDDSSLTGWFFKLLDDYFRSKRVTISLVFTTLCWIKSVTALQGDRCLGRTISLSIMHKWDLVERLEDSIAHGEVRRADQALHGKLVDLRDRLKQSDNTIGLLRANPLLAGFALLDNQFHFLHLGSESILVTSRFRAFCHLYEALCDRQLLRRISFVDDLVSVYERAVFTPSRASASHGAYFRTYMLSSHFSAASVDSIIRNKPVPARDNWVRVREHYHFRDLSRVYRMLVEKDTSVLPMDQSSLTWPSLLDAAMSIATSELFESRVLARDMLKVNDDLTDLFNALCDTLDQRRAYDANMARDDVPGWSQQYITNRALEDAVMLPLLPLLDCLQHDESIQENSSSAGLLRLNSVVARGLLDAEGVAQFARSAAVVIERWFQQTVPIELTFFTFPATPDWVQQEFGSAKIERGGGSRDAEYNAFSKLMDMFEEAEGPLSAFQLAVLKEAIRRMPSILALTSVGTAEFTNLSKFDGEVDVRSELSSLLHHAAAGPAHDKRLVEWMIQMGALVFQSLHCRHPPPPGALAGVVSRDHLYNALAVHCAAMVGQCDIMRILLEAENKRDLNTCTYRTKESLAHLAVKHNRREVYTLLKALGAEVFNRDAAGNRVSDLTSDPEWKRKIVALMMEQLRQLEVLDAHKDRSGIFEKENEAQSKRLRQALMQQRDEARTRQTKTTKANSGGRRESTGTKSSSRTPNSVQMIGRIDMQTTPSVAVEEMLNRMQQLFTSDPSALDDVTLEPKEDVDTLKQSLELLKDPKIDVSAREANAKTAVETIEKLGGVVQHVNKQKQRNIFSKGLRERLAGLVVPVIHLTNKFHRHLQSQPTAIVANPNSSVSRLYNLCSVNTLWLSMVANTAEVLSSCKRDAQARELIDLMERCLIKLPRPRDQLFRQWICQYVAIRGRLGLKGNASTPQVAAQLEWYLVSAIEEDDDALVQLDRFYGRGHYFSAELKCEKRAAKRFANAVYRALAEDTELVFIGQRVVASAETQKKLRRIADFFSKQSKEHNIQIATDSFQPATTELHLNGFIFSERGILRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNZ9</accession>
    <name>A0A8K1FNZ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNZ9"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="290" mass="30765" checksum="BC60EC98C6D65357" modified="2022-08-03" version="1">MAPSTTTNNNNVWLITGCSSGFGRELALTARKRGDLVIATARKVETLKGLQDLGCEALTLDVTADDATVNDIVAKAHAIYGRIDILVNNAGYTSNGAVEEASSEETQQIFDTNVFGLLRVTRAVLPYMREKKSGTIANIGSLAGYAPFPAFGLYCATKFAVAGVTQALRQEVAGFGIDVTVVEPGLFQTNIVGAGSFFKKSIPEYAPLTDFFKELAENGIGAPSADPAKGAQAIVEALTHSGRGEGRALPNRLPLGGDVRDVVQNVLTTGQKELDEWKDFTDPKAFAFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP07</accession>
    <name>A0A8K1FP07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP07"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="131"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="341" mass="38683" checksum="F588E2B2AE9732CE" modified="2022-08-03" version="1">MEASLPMHHHSVNGGDVYASTQPRSPFQDKMIRYRVLEFAVAFVMVAVGGVFSVIPVHERPIPAIQVQIDSKKTIYARDPSLDRKKLAEQVPMMVLAVAGTLVPILVNLFMNFAMPKFYRIRIIPHDTRDFLLSLAQSASISLLLTQFMKNITGRFRPSFHDMCGWDYKKVWDGVSNLCQDKHMEQEARKSFPSGHSSYAFATLFLLTLYLLGRVRINTHHRHETMFRGAKKMSKLFLCFAPAMVAAWVAITRSLDNWHHYSDILTGSLIGMFSAIFGYSYNYGSIFNFESAGVPYQEVHSLRKKDDHKMRGHPLTATQSTTGGSLHEMPLTKAEFGINMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2B4</accession>
    <name>A0A8K1C2B4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2B4"/>
    <dbReference type="OrthoDB" id="409644at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042856">
        <property type="entry name" value="RSP14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599">
        <property type="entry name" value="RTDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="320"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47667" checksum="A8170639E295555A" modified="2022-08-03" version="1">MALGLSCVLLWEARIDEFGNPGLAPVWNQEFSFQAIDPQMDQLHVKVKNTGFTSSTLIGESASLSTCFSTVDSQGSFLYRRTAPQHLTLVAAKSDVPEIPYDRVTEAFGVENWPHLLHSLEDGDEVLKKRVLLAMSTVFKLPQDLIMCLKIGVLEHIEQGILDENQEIRELSALVLSVILESPLGRSHLMTTEMPAHILPVLQSSTHPATMLHLYNALLSLSRVFTSAQLLTKHGYLTVVVTHLKRSLSDELRLRVLQLLKNLVNDGIEGTVFKAIELDSLDLCAKYLYDANAEISAAACDTIAALGYVEKAKKIAVERGAVKKLCTLLTESQWQIVAASTGALMCLAVNDDAKRVMVASEALHTINQLLQSSKYIVQLNTVKLVSIVASYPPARRQLNVSSTEYHLRSLMGDSDAVLAKSAKIALRAVQWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2E6</accession>
    <name>A0A8K1C2E6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013097</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="34"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="608"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="781"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1402"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1718"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1857"/>
            <end position="1890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="513"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="965"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1324"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1761"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1764"/>
            <end position="1777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1890" mass="206081" checksum="77A93066BC78289E" modified="2022-08-03" version="1">MGNAAPRAQPLTQIDNSSQYRTYLMDYSPRSMNIIFGSLIGDGKFLKSIYCKCEEGSLVVKLYRKYDPDEKLDSAEYSLRRIREAFSLDHQPNLIPYADYYLSAKNNVAFLVRQYFASNLYDRICSRPFLTTIEKKWIAFQILRALEQCHAKGICHGDIKQENIMVTSWNWVFLTDFAPFKPTYIPEDDPADYNYYFCAIDATRRGCSVAPERFYGSSTASNASAGAAAGGAGAKGTDAMMLSRLADSELSVEDVDKALGYATLPTPGGTMRSRRQGSLLQSMDIFSAGCVIAEIFLGGKPLFDLPSLLKYRTGDEEYLKNALRKIEDPELEDMLLHMLQLNPRARSSASEYLARFTRAEGNALFPAYFDSFLFRFLVLVLSRGGKVPDARVRLVCKYYGRIVKEVAGVDDPEGEEFFKLRLREGYGSDRQLSSDLLSLDDGGHVAQRILEELDQSFPGDDRKDERVKDREMTLSGTAQKKKIEKLNEQYQALTEKKKQTLLNDLPLLEDEYKEEEPASLDEEMRAKKAEADKTSAAYRKSSKSRATSREQPSQQKPWGSNRNGIVIILSLVCASLRHVQVPESKLTALYLIRYLGQYTSDEVRLQRLVPYLLEVVDDASATVRALSIRTLTFILSLVKSFPLSDASIFPQYILPHMVKFPVDSDELVRITFAECLPLLAATSRRFLEVAHSMKQQSMTAPNSTTSVTNGSSNKLNADALYLASSNFDRELNRLHKMISRFVIQLAAPDQKTSSSLVKRALLVDITRLCIFFGRERTLDVVLPQLITFLNDRDWELRGAFFDHIAGVCAFVGRVTVEQYILPCIEQALFDVQEIVITKALDCLGALCQLGLFQKNTSALADKAKMTSSLLLHPSWWIREAALKLMCFIAIQMGSVDANVFLGPLLRPFLKKSMIFLVGESEVAMLPRLRDCCRPFVSRETFDAALIASSSGTGLDPDGFVALMGGDDSNGARNSENGSSRRNGRGALTSVDSLDSYSVNRLPPPVPSSSMDALSLNTNVYEHKKNEMQGLKLMQQYVAIASMHMRSKMELAHSEQAARLMGHGRAEYSAVASNSLMSGIRKLGRSSLHVLYVPDMRFALAVAQPLKGQNLVVASSQHSSAGGMTPAASSSTALVVAGGKQTSNNRVFTGQAGAALLENLSLSLIVKMYGLVSPNLPMSSMPLSPSTLTSGAFDDSAGASAYQLQTSIDSNHFGSTSGAMAMLNLRDMYGGDNVGGFIDNHHTPPTLSPRQRIAKKAHQGLFNGSPYRESSIDPALTNPRKLLARLTALGVPPLPPDLGSLRLLDGSVYSIYAHPASPHSMVQHGGMGNSTSSGVGDRGGIASNTSSSGVGSAYGTGGYAGSNGPASSSGMGSGLGSNSGIYHSSISSYRNWRPRQNVLVAELAEHSGAVHRIGAAQDFSFLASASKDGTVKLWSIRSMNHSINQGSRSTYDGQAGVLTDMVVLDNSHSVASASSNGTVHVFRVDKVNATSGNFQTTGLREIRSEKSAVMVLDHLNNVTESLLIYATRDGTIHAWDLRQRREAWKLEVAPELGYVTCITHSLDVSWLAVGTSRGFICLWDLRFLVLIRIWRHSSHRSIHRLKPCLGLPNTLTLEETSVPLVFVAAGDGEVAVFDLSIGACRAVFRTLHVQAPEADACRCPTLLHVPIPHRSRSVLGSFLGIYGIANAFDEIAATPLSEEPSVRAILCPSLHFRGVADALITGGEDKQIRYWDIRNGKQSFTVCGNSESKSFYDNQNAPSDWWRMRSSTGPGANSSPEQSDALVSAASMGVSGGGSSSSSSNAITKPEMAWSKLSPPIITICQDASYFASSGGLSSSLAAGGGVESAVTMERRGLVPPSPAHSDCILDLTLVDLNGPVLVSSGRDGIIKVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H4</accession>
    <name>A0A8K1C2H4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71445at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34894:SF5">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34894">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE RSMI, CONSERVED SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="1293"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1578" mass="176959" checksum="FCBEB9C48333BE8B" modified="2022-08-03" version="1">MDKVSEVSLPTRTASVCSSSTGTKSQLTAEDDAAALIRSFRRKKYVRARLLPLESDIPAVSSPSQWHLQRRPPKTSPARTRTQPTTAMTAQTKGLSIDKQAILMRLPDAETSNNRENDIPEAETTDIERLQRVHALLTSDKEIQQWINTYETEKSSFSSFALCTEMKLDEIQDKYVSLAGRPNAVEAAACCATLLKMPGIVGCYRTLLQKLTLGILSVVYVPSTKTDDLPADTEAMTMLVRGFYARKTYFQRVLELETQLGTARSLTDAQTLRSLTIDEVTELVRHVPFRVMTYGLLGAYAQHFPHLEQLLRHVQSKIKQCQRDFYRQYGRKMPRSSISHGKSDDDDDEHEGLDPEDPAYPLQIPLTTSTQICRAISQHAVLFSASGKEMILCSILEFVDVDSFKDVFKRFDAHGKTCFLHHLSVLESSEHLQFILEKLPNGGDLLFRFYYALCGAGGGGRDECKASASAKHVFFQKILSPEMEYFFLCDLAPYLNDDQWQLLSQEYEKHVQERKARRRRLRRSQDAGFDEDVDDDDDVEDDAEDQQGNAQRGGAQSKLEHFQVLVWNYIHHQRFTSVQVCSLFQTALLPSLEEKELIACIDLCMEKLALDVQWKKLLARMEELDTERPSTAEPRSPEQQEAVRGVRGAILQRLYSGLTREERVSWLTKTAGKLGLTVVNPAMASKETKSKKSVEPVPAAVAASTQPLAPAFNLEDPKSVISKLRMDLKIKWLEALLEMITTDKETSARTTMLKQMLLPFLQGQQPPANTTITTQETKPTPVDAEKAIMDIISRLNEADAARVWRKVLPESIVPKPKSMLDRATSPILELQIQENVSRQPTPVVPEPESPPQPWYAALAPNSEVATAFQALLADKTEQQVLEILRNGLKPAELEKTSSQEHEEDDDERHGLDNFRSTMVKRKLSAVLAVAEPMEWQERVRIGMLDVSTQTMEIEPETSTALVEPTPSKPPPRAPLTMNALLGRAANAAASSPKKKDAKYQKLNSTAVPRSVSTLITSWRVNTDQLLQFAKKSMQTVLRLIADAYGEMLTAGRRKATAQAAGNSTVTGRQIKDLTLAQIVYQQFLHSYGLPGIADMHLLAFSCATEAYRTQHLRVELFARFVFEEVPKLELSNLLEFLECLVSDDNSTASGASNTTNSNSSSNNSANQSMNGNPTTKRQRFVPRIVVPDKENWQIPLEKAQEAAQLCFRAMRKQAVTAFCDRLTLLALNGSTSFVPVYTNTGRAGPTVDSGRMSPGIPLAAPTTTASSDNSALMLNVDHLLQLVVEEWREEQLRREGHLLNVFRAGDVNGDGQLTSAEFTQIVLTIDHTRELDDILLMYSETLRRTECESINADVFLQVAKEYELDRAAWNGDGELRNIVNDMNELNATWSHVRPFFLGTLEALVRDLPTLHFLRVCEGAGCGCLKCILDGYIGFQRMRREYFTSNNPRLLPSGLAVLSKRTSVVSEALVWARFWHLMRQLYEAVAESPGIITAWEGANYMRVDPVPRLAPRYLKFRRPALPNILFPDTNRISAMMSRMHDPEAFDAETIRQQFHRLLQLMMYNTSGSGVGEGSVVSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2S8</accession>
    <name>A0A8K1C2S8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013307</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the importin beta family. Importin beta-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2S8"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000028">
        <property type="entry name" value="Transportin-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="348"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="905" mass="101784" checksum="E3AE44E500F0A650" modified="2022-08-03" version="1">MANAWQPNPQLLQEVVTLLQAYLVPNNEVQRQSYEKLQQYQQNLEFNLYLVHMLCAAEFEANVRQIAGLLLKRNIKASNVGGSKSPAEMEMLALIRAQTLLVLADGTHAIRTTAGSIVTTFVSEYTFLDEWPELMPALFAYLEQQDENAIAGAFGALVKICEDSAAKLENSPSRPLTALIPKLLQYFYHPHANFRRDALDCLNNVLIYMPVGLVVEMNNFLQGISHLTQDPSPEVRKLVCKSIVILLEVGVQYLLPHLESIIQFILRASQDPDETVAIEACEFWAAFCDVQQFDQIKGSLQPYLPQIVPLLFDRMIYSEEDLATFESEEQSQNENVPDRPEEIKPIFHHKATSHRHEGEEGLEDDDDDDDDYDDDDDDDSLLQWNLRRCAAASLDNLANGYGNDILPTLLPLLQHRLQQQEPWPLVESGILALGAIADGCYSGITPHLPQLFPFLMQKLEDPAPLIRSITCWTLSRYASWVVEQGDHDQYVRPLVECMLKRVLDPHKKVQEAACSAFCTLEEEAREELVPYLTPILQNLMFAFGKYQAKNLLILYDAIGTLADSVGENLNQPELIAILMPPLIAKWNVLEDRNREILPLFECMASVSQALSNGFQEYAMTVYARCSRIIENELLADALFDQDPSSCEEGDPEFVVCALDLISGMLEGLRHNSQGLVANSNILNLLMACIKHDVLDVRQSAMGVVGDLAKFAPEILIPGLREMLPVLIENIDPDMPTVCNNASWSVGEIAIKIGAEMEPFVENCLAPLVSMINRPKLPRNLVENCAITIGRLGMVCPQTVAPHLQDFAKRWCRALAHVRSPEEKEHCFLGLCYMVKVNPSGIVPDFMYMCGAIASLEGMNIQNTELKEMLYQIIHGFKTSLGENWPKYFASFPEPLRNFLTTRFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C395</accession>
    <name>A0A8K1C395_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C395"/>
    <dbReference type="OrthoDB" id="167488at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="72855" checksum="50ED7714C9904BC4" modified="2022-08-03" version="1">MLQTPPPAETKMTARGGDLLSGDERMVYEQQCDQVLCEAIAEFAGFDGVVDPEEWQLVERREELSVYKSVDTQSESTTDEQDKSERIWTRVIATGYIRGQVEDVTNGLYCESDRDVVAVESLLSGAIVLDGAALQVTERRGSHTPFRFAGIKWHSAQVAGGPRDILTYERMGMTLDVDSTEVAYHVVHCIQDHQDWFLTRSGRRKGVSMNSRRPHPYTICYLYRKVTDDLVQCYIVGEYSSKASAGSQRSMEELITERVLMVTNTIACSEAKKLSRLVEDCKDTPAKRSRVCLRCRQRKSVADPFRVCGICHKSVCKSCRIMKVLLDLNETTKHPETEAFCGKCLTRANVSTVPTAVSSARSQGSPADRVHRMDNDRHATENEGDGRRGRDRDRDNGSSRSRRHVSVPPSSHEFNYDELFKRGNGMTSMPVKSKSSKHTIREERSFDDMFDATGGMQSVPAMGNAAHHMSEDDASPQKRRHRISKDQLLSFAMRKLRLPGRTNSTNTTPAVSVDNSPSNSQDLYLATSNSNEAEKQYSRHVHRDNKFRAETEPIRKTTRHNSNKAAGKSRSPYLTASQPVAIEYKWRVGKGSGGDDISKISRSLDSVASGAIKRQPPPQRPVRNALSRTYSLDDPVSKHNFRNDLYTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3J4</accession>
    <name>A0A8K1C3J4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Replication factor A protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3J4"/>
    <dbReference type="OrthoDB" id="188186at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04479">
        <property type="entry name" value="RPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12084" checksum="6B890CD1017C7869" modified="2022-08-03" version="1">MNFGGATSGTAPRVNKKTMGSFVGRTVAIVGAVESHMPTAVVLRTSDGGMVNVNPMPGSDYSSKFVEVIGRVVDNNTLQEFKTTLFGDNFDLETYDQFVQVAQSKFRHLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C527</accession>
    <name>A0A8K1C527_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C527"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="75" mass="8094" checksum="B2A004FCB11300A5" modified="2022-08-03" version="1">MADVHQRRVAQALKAACEETAQQAIAATTASGQATRVHHKNRKFGSRKEAMDAKIAAAKAKREAKQTTTTTEQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C545</accession>
    <name>A0A8K1C545_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C545"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="147" mass="16369" checksum="0BBEA55B613154EF" modified="2022-08-03" version="1">MALKRINKELQDLGRDPPANCSAGPVGDDLFHWQATIMGPEDSPYAGGVFFLNIYFPADYPFKPPKVNFTTRIYHCNINANGGICLDILKDQWSPALTISKVLLSICSLLTDANPDDPLVPEIAQVYRTDRARHDATAREWTAKYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C637</accession>
    <name>A0A8K1C637_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C637"/>
    <dbReference type="OrthoDB" id="92096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="39565" checksum="CF0641F73CB8138F" modified="2022-08-03" version="1">MKVYTSVVASALGLTAVIADPSVFRRLATDPISYPDGLTKIPSTDAFHMQPVRAIHARVQSDEPAWDDTKKMFVSKYGADFDAKFRGALDTVNTASVEGALMYVQAEGIDYRTRGSDTTAKCTRKNGMKYVVFYDILIAQTNETLAAYPNAEYGPMLPMDGGQCTPTSTTPNVTFPNECYMINGDNNKPVIGPFVGAGDKSTEPRAPYPNTICKVEYNTNADGTLDSSIDFWANPFTAASNTARANKLVKAYTDLQATTTTSTIIASTAVANFKALPTVASLTSANPPCYKSMKACASAQYGCKRALYSQICTLCTADGQDGCVKKPSDYTYPTLEAATPIPTPAPSTASPMSTLAMASAAMSLVLGVFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6C0</accession>
    <name>A0A8K1C6C0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Chorismate synthase</fullName>
            <ecNumber evidence="3 7">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="7">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="3 7"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6C0"/>
    <dbReference type="OrthoDB" id="1721239at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="459" mass="49825" checksum="5A59D187ACD302AF" modified="2022-08-03" version="1">MSTFGRLFRVTTFGESHCKGVGCIVDGVPPSMALTEEDLQPQLTRRRPGQSKLTTPRDEKDLVTIMSGTERGFTLGTPVALFVPNENVRPQDYKEMGAVPRPGHADYTYQMKYGTRAASGGGRSSARETIGRVAAGAIAEKFLFSKYQTSIVAWVSSIGNVEMPRDMLHDPKKSTLYTREDVDEIGTLRILRDPSKWTRVASDDEEYTKKQAAADAEYELIFVASTDDLKTPAYVDKSQIVYNRRGDIVPSPDNLSEWLTDDLVPVRCPHPPSACAMSTEVRILKHEQDSTGGVVTCVIRNVPVGLGEPCFDKLQATLAHAMLSIPATKGFEIGSGFSGTSKRGSEHNDPFCSSDRTGHLDVTKNDAGGVLGGISSGADIYFRVAIKPVSTIGRAQPTVDYEGNETVLEAKGRHDPCVLPRAVPLVESMAALALADAAMIQLSREGCMDEPPAKKSRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6E8</accession>
    <name>A0A8K1C6E8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6E8"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000009">
        <property type="entry name" value="RNA-binding protein PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="26031" checksum="5FA838A6D278C8B9" modified="2022-08-03" version="1">MEIDSVAGQDVVISTQAIAQQVQHDAMDMDEHDDMLRPDFPALSAQEAAGGKNDFRRIRVPAHRYTPLKNDWPNLMTPIVEHLKLQIRMNTKTRCIELKNSPFTEDSGSLQKGADFIQAYMMGFEVQDAVALLRLEDLFIDTFEVNDVKMLKGDHLSRAIGRIAGQDGKTKYAIENATRTRIVLADQKIHILGSFANIKLARDAICSLIMGAPPGKVYNKMRGVASRMNERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6J5</accession>
    <name>A0A8K1C6J5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein assembly factor 3, axonemal</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003397</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNAAF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6J5"/>
    <dbReference type="OrthoDB" id="538817at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039304">
        <property type="entry name" value="DNAAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028235">
        <property type="entry name" value="DNAAF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 3, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118:SF14">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14740">
        <property type="entry name" value="DUF4471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4470" evidence="6">
        <location>
            <begin position="17"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein assembly factor 3 C-terminal" evidence="7">
        <location>
            <begin position="145"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="59990" checksum="D463950F94C0B883" modified="2022-08-03" version="1">MARTTSGVMMSLGTVNMWGFSPSFDMQDGVASPHKEDTPLNLLLIGPGDIRHVLHTIAHRRRWGKQLRPINIYVYERSVETLARHMLLMQIAQDWELPLRQRVSTFLEVFGNTLVQERTSAYLEEKAKALIDSVHYERGWLANQFDLSHLKMKTRDELVDNFHSWFQKVRFDVVKLRDHRLRHYYEVRYDYRNNLIDWDYTMTLKKIENASVIHIRQYREWRNSGIAFEFGDQSYTEPNRSMAAFTEAHKKNHGSVLCRGLWADIIVSPYVSFGVDCETSNKFAEQLFEIHNKGTGVEQNRHNTTQVAVYNLLSYLHEIETGDVYKMKKAHDVYSGIGEAATSVSNQDDEKALPKIEEIDEEEETTGTSKNSDRVADAEARERAKTIVESLEGVKIIPLTGKLEDLYSKKRYHHLFDHVFLSSQHCHTLQSAPDSKEAPTFSNLLSDDALVSVESPLFLLPLTEDQRLLYMEKLVEMTTAHLLKPVSATPKSFDKSDLFKIQNASLRFQFTREHDGQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7H0</accession>
    <name>A0A8K1C7H0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7H0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463107" evidence="3">
        <location>
            <begin position="22"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="160" mass="15533" checksum="5A9CE37D46E80064" modified="2022-08-03" version="1">MFRTLSFLAVLATFAVASTSADVIGELEAKKAQAELELALIESVISKINAEAKTFSLATAVKAEDSVKATAASSAGSSASATITKSSNGSGSGGEYEIETPKPITTAPPASDATASSTSSGSGSATSDDVGTPVPAPSSAQRIAPVAAAVAATAAALALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7J1</accession>
    <name>A0A8K1C7J1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7J1"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="303"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="61577" checksum="0058DF7440FA0E3E" modified="2022-08-03" version="1">MDPLGMTVDSFDVTDIDGLLGAYRTGYILLDGILCLVAVAVVQQLISALQNDADSSVFAKLWAFLYSDEATVERVIEITQRYNRDGYKVWDYDQKNHLLQKAIGQYIAEISGLEIKNGKYELIDVVEKEEEDDYWTDSEDEDGAETKEDEPEDTRRVDCLPIANEWLEVEPGIMFRHELVTPENPGERKGVTQHKVIYRFSTKKANGTDGIDAFIEKAYSQYQELERQRVKEDKSRYFYIQSGTIDSETDEGVKKSSMAYKRYALGEEKTFENLFFNEKATVMQLLDNFTNKTGKFAIKGFPYKLGFLLHGPPGTGKTSLIKAIAHHTKRHIVTINLAKIKSNQELMDAVFDLKFTVHGMDTAVSMSMEDVIFVMEDIDCASSVVGKRVEEPAIKSEPSLEPELIDDYLTMRMIKKIMDEDQKKQKLNLAGLLNVLDGVIDCPGRIIIMTTNHPEKLDPALIRPGRVNKKLLLSYMGWIQVQQMIEYYSMAALNDEQTQSLERMFAEATHLVSPAEVEELCAEYETVDAILHGLERIVMGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8I3</accession>
    <name>A0A8K1C8I3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8I3"/>
    <dbReference type="OrthoDB" id="200229at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="31492" checksum="C2ECBA39C0EABD53" modified="2022-08-03" version="1">MWTASVRAFSSSSLTPDAEFLLGVQHLMGKTEHASVQYAVLHWTNAAEKGHLKAQSALGNLYLKGHGDIAKNEQLAVRFLQLAADAGHEGSCHELGKLFFHGSSHVTQDHERAFVYWSQAADKGHMAASYDLGYMYQHGIHVPRDGTKSVEFFRQAAKKGMPEAHRALGTAYLSGRGVDQSADKAVVHFRQAAEIGHAPAQFDLGACYMLGRGVARNTAKAAEHFFLAAEAGIPEAQLCLAQLYESGDGIPHDQEKAVQYYQLAAQNGMDAAKQALTRLGAPLEPPQSPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C973</accession>
    <name>A0A8K1C973_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C973"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="194"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="38165" checksum="670091B239171F17" modified="2022-08-03" version="1">MGRLARKLHVGVRGSLDIELEHSCILPGETIKGYVRLHVKKPIVTSGLSVIIGGWERLYWETTDHCGMRWHRRSFKLLHVPLPLFEPGTLNGATTTINAGTYDYPFACQLPSVLPASFEYTAHRIQSMERVRVSIVYSVDASLAVEGFMKADLMHSAPFVIPPGIRSLPVPVPTDQPLVFVKRQDVRALGMIKQGAFHVSMTLESNIIDASSTIVAHVQLENASKSPLKAICLRLVEDISIDRHRKHFNRTRSTSRVIGCRFYAAKTLKAMLSRASGPNLTLQLPVTPNDIYGFEPLLPTMSSQHIIALRYRVELECSFTLSEHICVEAPVLVIRGPSRALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA18</accession>
    <name>A0A8K1CA18_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24118">
        <property type="entry name" value="POTE ANKYRIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24118:SF99">
        <property type="entry name" value="POTE ANKYRIN DOMAIN FAMILY MEMBER 3C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1486" mass="168734" checksum="77C031EE05B6705E" modified="2022-08-03" version="1">MKFLLSHGLDKNAVDKNGWTPLTTAAHYGHLEMVWVLLSRGVNAEIASEIGYTALHYASYKGFDDIVKALLSYIVDVNAVNKEYWTALHLALTITKDGRTVLHLAAAKDCHRVIVALISRGAPLDVGDRSGDTPLHVACKYRHHAVVELLLENNCDPNGENKASQTPLMKCLQWKAGTKDFECILEIAYLLMTHGAVYERVEGDFPLPKHTHDDANSIMACVLHWSTEQRRGKQQLTRVPSETFARGSTAVMTYLRELYASKEPELITRHKVCVVGSSKAGKTSLIKSITSSNPTLVEENDRTIGVDLFHLEFERHALQEDRPRTHSITFWDFAGQDEYHGAYSLFFSRTMYLLCVDVKAFDQVAQDSRLCDDEDEAEALLDEFVRDRVWRWFRLIFTHRPDAQVVIVATKAEALGNNCSSRLNDLRHKLFQILGDYKVAFVREMRREITALRATTNGTTRQRADYLEELRLSLDNALPTSWTVLKILDQDSIQPARYAIQKAIVADGQGFLMPDKYTRVLDEIKKLRKAAFRQSTTARIRQTFVPFPTLQQKLMRSIPDLAGADCKSILETLHDLGDVLWYSRDGLSELGDTVILDPELLVDLIRQIGCHAPVKVPKSMPSSHYQEFITDVQTHGRVAHDLLRTFSLWKRLEYPDQMLQFKCLLERFQLAYPVDSIMMHADSDIIVPSYWRVRENSRGQSEFEPLWARIEGCNPSTVTHFHWEYDFHFEMVESVFEQLAVRSYRVFRNREAHHRRVESVPNADFAVRIALRTRGYGSHMRQVIRLEAAANENAVASDLLRSLYFAMEDVLRECPGVFVTRLAVAPGRRERTEKVIETFTSAAPAMQDVMRRAMDWFPEGAIEWFSQDDSPPRSMKTKSRDPGDEIYRVHRPQESVNDGVRDICDKVDALNEKLTNLHAGAGNHRDLPGLWMVELVKTPKTKLIVWILSEISGRCFHRPIEIDVSPKFLAEYGKELVIGLIVLASVVFNGGIPALVLLKQTVWKAAPALSQRVDKASRLHIMIAEMDLDDDMVVIPTINNVKPAHSYSLLNRILTEHDSNFDIASVSSLTNLECAMLSNGTYQWAHEDDHHARDHQLRVNPVNPCVASNPLSNGTLDCVPTCDKPTFYLCSFVVEECFNMQSVYCSWDLVKGDACVESNETMQNPHHDPKKQLLWLQAFVLSSVRSVADLEDMELRVTLKRPSRLPLQKDRILDWGCIRLGNLVEELAAEPTEPCHLVIPMTKQEGTVVSGFCFHDPIEIDMSSTFLRDYGEYIQAGLSVVAHAIFGFSGTFIVKKTIIGVRDVLGNRIDRAIRMHSIAEGLELVGDLSNLRKCALRVTLKRSGRVFKDKTLGRGTSRFYEVVHSPPDNAEATGHSHKSWCLRIPLGEHTKAEMRSGRSRLDTIDPLAVFKTIYTLMAWSAEYEASPDAFQFEDKELQAEAATLRLCIQHWSTERHNKKQILTSVPSEVFYQGTFAVRRYLSEVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA21</accession>
    <name>A0A8K1CA21_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA21"/>
    <dbReference type="OrthoDB" id="10464878at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457922" evidence="1">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="12198" checksum="F527533F7725E8DD" modified="2022-08-03" version="1">MLLPSRVLMIVSAYLSVPVSATRFSFINQCPHEIQLWDNSQLIRIPVNAPPLVQNVARAGLMWRHGYNPEATLAEFTVIGDGKAWYDISIIPPGVSRHLIKSKIVFCVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAC0</accession>
    <name>A0A8K1CAC0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAC0"/>
    <dbReference type="OrthoDB" id="119121at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37204">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37204:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="30345" checksum="A4E5144B743A49C0" modified="2022-08-03" version="1">MSEEEAVWKREREATYEDLYRSGRAGVSPEGIAHARSYFYLKDKEYVCRPYVFPTESDAVYLVAAEIPADFARVCRELGDDLVGLIPRVSGTDDATGYVNDQATMHMTIFHTSHPDEMMPNAKSRKEDQIAKVHELASRFPPLPLKPHRIVLCSSGAIILLYEAIEDGVADPYTIDRLRKLAREEFSPMPKRMSKSLMHTTLARLMDPEISPEVIEKLHKRCEELTERLHHEHPSVVIQNLWFVEETHHYWARGPTTVISLGGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK0</accession>
    <name>A0A8K1CAK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK0"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47484">
        <property type="entry name" value="COMPLEX 1 PROTEIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47484:SF1">
        <property type="entry name" value="COMPLEX 1 PROTEIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="88" mass="10556" checksum="47DCE74C9381777B" modified="2022-08-03" version="1">MLVDKRKEVLRLYREILRTTRHFQWTNEQGEQWGAVLRKNARMEFEQHRHETSSENISRMLIIGWKCVEDVQAKMASKATELSQNQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAU6</accession>
    <name>A0A8K1CAU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004372</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAU6"/>
    <dbReference type="OrthoDB" id="111832at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47446" checksum="E329015412C6D633" modified="2022-08-03" version="1">MLSHSPIPIEVVMLTRQSFQDLKTPVDAYALGKSPVVDHEGGALRLGGRPSVLSLQHIGLLAHIASVGVVFGTVYGVIYAVLNNYFAMSATLVATAQALVRIPRVLRIVFAAFTDCYPIFGYRRRPYLLLGWGITFVSCLLMAIWPMGASALVDRDASEHGIKLIFLMMLANLGIVVAFGAADGYMVELAQREPEATRGTVHTTVSAVRYLFMILSAFLTGLGLNGIDYGGSFHWTMGLNGIMGVCAGFAFATMVLCWFCMTEEKVTSTKSGSQFCKDLFRIIQSRVIYRLIAFRFFRQIFSHVSVTSDTIFQSQWGHVQPIHSGIGNMLASVISTVCIMLLKKYGLGWNWRTIVVGCQLVVLVWAAIPTMLTIWDVCRSPWLLLGLPLLGESPNTIGEVMPGLYIVEVTETGFEATMLGLGHRDAVRDCDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAW3</accession>
    <name>A0A8K1CAW3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAW3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="211" mass="23837" checksum="C718C56CC076ABDD" modified="2022-08-03" version="1">MFEMATKGESTLEDEEDAALCASEEESKATKSAMTGTSEVKTKRMAREKKRARPTMEYQGGGDDDDEHGRMKMQRTTLPFVSPERKPRRVAGAENGVKRPQLMRTPLQVRASSKARPVQGAAEVQQQVATVRKKLKTAILQHKANVLSKLEERYTTLRKKVAAELEDAEQQLQALRKANDTINELAERKLQVLTKMAATEIMWVQKTRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB24</accession>
    <name>A0A8K1CB24_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB24"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="36540" checksum="ED0CAB7323308F5D" modified="2022-08-03" version="1">MEAELLRLEDDQETLRAILAMLDEEEASDMGSLLGDELFPSTASSSSPSTDEERSLEVRIRIPPALKMVVGETESPPQRIPRNRRWHYQKAEMQSLRDQVVQLEQVLTHLKNKQQSIVRNDDVSGNLWRAIAKRQQQQRHAAELENMKLKEEMERHSKIAKRTEGVLHKWSQRLQVLEDEEAHAPLSEPPMITSHAFGMEADLARQMQGMSLQNERATPSSVFESKTSSPQSDLMVLKDRVASIWSRLQAPAMQQPTSKSRASKSSALDLGISLTSQMEDASVSMMMSSSSDSTSIPTLEISAFQRPFAAPASLLRLFGRAATTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB46</accession>
    <name>A0A8K1CB46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000141</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB46"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480678" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="10">
        <location>
            <begin position="83"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="11">
        <location>
            <begin position="397"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="82720" checksum="61B0F441F4E8C2CF" modified="2022-08-03" version="1">MKTINTLLGLTALAASAVTGATLEGAGLVVNSTNSEVNIAPLGDFQLFEALSTEAPPSNIFAYTNRHSTFLPPRYLAPGLVGNAAIPTNNWWGNMIAYSTDAQPNPVWANPYVFRATIAAAPYGLTLSYPYTTRALGGSTGNGNANQFYLHAVINDFTLGAAEFTAKPTYEVYGWDDLSVSVRLYRAGDASSKIESTLTSGMAIVTGKYAKLTPKFSTVHAILTVNGASVSNGKTFTGTRFVVTLNSGQRWVIYSTTQITLRVDGSNLVGTSQVTTNIRTALASSDAHLAVLDRTRSCIIEGGDVEARDTNTYAFNMKTSGDCSSGLFHYLQVHHLDTLDRTYAAEVSGADLFSTTRGKMTGVLTKTSPPTIRFTDTRSVPADFYPPRKPSASVVSANNIKQTLINDINAAWSIPVGNSYYFNGKAAQKYANLCLLANDDSVTGSDKASILRQCLNKLEAIVLPFVENKWTYPMQYDTVYRGIVSSQGFVANDPNVDFGNTMYNDHHYHWGYWITTAAIINYLDPSWSRIAQMNRLTSFLIRDVANPSNNDKSFTKFRNFDWFRGHSYSHGVTPFADGKDQESTSEEINFHYGVTLFGKATKNTELTNIGQLMLKLNARSIQTYFLMQNDNRVHPPTIIANKVTGIFFDNKADYATWFSPEKFAIHGIQMIPITPVTEFVRTRTFVQEEWDQILSKIPAVVNFDVNNAWLSLLYANYATVNSGVALQRLRTVAMDDGLTRSWALYMAATRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCJ1</accession>
    <name>A0A8K1CCJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PRKR-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCJ1"/>
    <dbReference type="OrthoDB" id="10067079at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22318" checksum="8A52AE8955FDEA3E" modified="2022-08-03" version="1">MGRYTTVQTYTDQDAKVAALAYTTATTTGESNGEGAGAGVEASAASNKAVEDANDEDKFHMNRVDNVSGSSAGAGSGDFHMYRAARRRELERVAHLEKEHAKRKDQEDFETKRKRNMEEFEARAQKRAEKRRRRKDRAKARSLDDGSEDEGGEPKEDKEKPGADDDKPLPETPGGVPEIPNDGSFLERMLAMQQQLLKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL8</accession>
    <name>A0A8K1CCL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68481at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="495"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="905"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1142"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1255"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1398"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1461"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1573"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="924"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1115"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1634" mass="184400" checksum="B3AAB9820E50D84B" modified="2022-08-03" version="1">MGKGSVFEVGHNVELELFLLHLSAVVAFIVILEFFLHKLEHKLKRYPKYHEMMTKVFGELMILGFIGLAIKVLKELADLNAYSKSMIAFQAADLAVFIMAVALILQSICVFMRLRVQNILWDKAELIGSQELLTTIQAHSESMKKGKTPKARDSRSLRDSVRGAANPARRRVQPKHYYDLVQMRLIRHFFLKKVGLPELFPFAKYLRQAQENQISHMLEVDVSMWIVLIIIGWVLHEVADFFEYQENLTESESIVPAFLVFAWGSALLQFAIHQYFSWAIRQVLFAACRFTGRSNWLVCLEEVAMHEIKSVNGEMASNAIEAMENIREAEAAKKSKKHHNIFTHHDKGFRLVSLIARNLKRRLSKAKTEEPAEASKGDPSVWIKWFSRQVWHFIVVSSLMFNAFYIALFIQCLGYQLSHISHMYGKVTLVALVLPLLLKMFFFQPRIMWGYTLVSSVVRVDLAALSDVIDHFSETVQLRSQLTETILDHLKANGQTIETVREALQALDPDHTGFIEADQMREFLNKFGVRLSFFGFNSVARLIFDFKGTSVPYRQLLCLLELGSTPTNDGVVDVQAGAHPTLNPLGVSGISHFGASGIDPLGASAVGGIHGLLQDEPVSPISELRLRRVDLSQSSRGVKLTSNRTSMFHLASHRMAMSMYRLDFQDDAIDENAPRSTRHPKPSTQAHGFDHAEFEDLLKNIRSKLVSDTCEHLARIVRVMRHAFRPLANLLVIALANTAKGSSIAIREPGAKLFSAISEYSRYDLTLFLKAFRLGQQERVRALVLAQMQVVFAYWTKDEVEPAYGEMVDTLRRGLKDPAGAVRTAARQAFCAFSDLWSERLDELVEIPPATIRELLVKEKPHAAITKAIKKKYYGATRERSDSAKDIRLRRAVFRKQTSSQAEGDDPIFVEVKDSPRRPQPVRRVSEAARRLLDPVQPIKPLEDDDQDDLNSLADEYQPARRASEAARRLLDPVQPIVPREDKGEDFMGNLANGVQPVRRTSEAVRNVFDPVESIEPTDVEDQENMNGIANGFPPAENIQPKSGKRVTIVDHREASDVFEPPHFDVESTRSTPRQSVFNFDHESLDINHQPQYRLSQDFSDSRPDAFLDRPIPSSERTPTPRSAANVTVRQRRRVLQPTAIEESVPSISDPVPSEGNLETFSSQPPEEFSFPVGQYLCPTEQIMLNPSSTHFELPEDSQDDIDETIFIPRVSVPSTVDREFVGLTPGATETAQDSPSKALLDLKQVMGRLKEIREQSEAQKVSEKTSKPGSFEEEHRGFASDDVHHGACEESKGTVVSRQPSVHTQEPVVDEKTFHKPYNFGMDASPALDHPAVDSHRELRTRQPVTSPNPREEADRFVQSLSIGTESEKVKPDFVRVQDTEPVSTQRRRALMPAHPVRARPSLTKRSQPPATTVPAKEHHPAQIANNNRQTTARDPRTEVQVAENQELKPIVRSVEVRGGDRLPNTDARASTANGQIDREKSNVKRSTILKPEPHRAKRGVANKIVLSFCVMLSAVFGVAGLIQASSKVRDAYDYHHALMTRMNDFESSVVESYDSVRKMDEKYAIWSEYVRELAEQDEANAVQQLENIQQEVEKWQVEMKNDLLAFKRSLSGDIIDAAFAPLRRENATTNEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCS3</accession>
    <name>A0A8K1CCS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCS3"/>
    <dbReference type="OrthoDB" id="2108802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35273">
        <property type="entry name" value="ALPHA-1,4 POLYGALACTOSAMINIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G07890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35273:SF2">
        <property type="entry name" value="ALPHA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside-hydrolase family GH114 TIM-barrel" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="167" mass="18748" checksum="0E5CA913CCFA8C4A" modified="2022-08-03" version="1">MKTRMEMAKEKGCDGVDPDNVDGMLNDSGFKLTNATQLDYNKFLAKTAHDLDLAVGLKNDLVQMEDLADDFDFAVNEECIEMGDCDDLKPFIANNKPVFGIEYKGDREKGCKQARELRFDTLYKDLDLKSKRYSCDDADSDSSFGLNYHRATTFVCSIALLAAAFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCW0</accession>
    <name>A0A8K1CCW0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">BRCA1-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000527</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCW0"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="246"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="504"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="375"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59886" checksum="C9EB3D1A47305D83" modified="2022-08-03" version="1">MFQIRVQQTPFVDGEEAKTEDEDTLLTEDGARFLTGNPQVCVSTGKLRFYRPNRPYLQWPTTSTTASPATLGLPAERNTLLCIVTVPSHMSPVELLEFLAGFRSDIQLVRILKDPERSNCMALLQFAAQDRADHFFLAHNGTYFNSIELERCKIVFVRSIEFDTSEPEPSPDSTEQKADSIEEEEEEAARLAGWKLMAPPPPPPGMTEIPTCAVCLDRLDASASGILTTLCNHTFHCDCLFRWEGSSCPVCRYSHGDIGSACEVCQTTEHLWICLICGHVGCGRYSGEHAKQHYQETMHTYSLELETQRVWDYAGDGFVHRLILNKQDGKFVEFPNPDATSGERSQLPPPTTAELEEGEHRKLEKLAHEYNFLLKSQLEEQRLFYERRLASVSDAAQQQTIAALEQDKKALKKANETLTAKASKLEEELTFVRELNKSLIENQKQWKERVRTLEDQKQRFEQETTTRIADLEGQVRDLMFYLDTQSRVAQSSYRDDIQGGTIQIEAGSAASTATNSSTASTQRRARRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD20</accession>
    <name>A0A8K1CD20_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD20"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="28094" checksum="FDA08533CCF5538F" modified="2022-08-03" version="1">MAQPAYSGADMDDERLRRVLMAQQLYPPEPVPTFPAPAAAFLDDEDYDGGGFDNRRVLVAQQPYPPEPVPTFPSPAAVLVVDEEYRGGDYEDLGASRVLVAQQPYPPEPVPTFPSPAAVLVADQLYPPEPTPTFPPSPLLLVDQPYPPEPTPTFPPPAPSVLSQDLTQDAAVSNVLIGDLVDQMALASSETTKNAGALRADNAVMSLGHADAPAPMAQLYVAAGLLVVVMGVVVQGVRRLRRTTKEDRMVDFSDSYEPFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD39</accession>
    <name>A0A8K1CD39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDRGK domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000840</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDRGK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD39"/>
    <dbReference type="OrthoDB" id="2285710at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044389">
        <property type="term" value="F:ubiquitin-like protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000143">
        <property type="entry name" value="DDRGK domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019153">
        <property type="entry name" value="DDRGK_dom-contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050899">
        <property type="entry name" value="DDRGK_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176:SF1">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09756">
        <property type="entry name" value="DDRGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01128">
        <property type="entry name" value="DDRGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="63"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="39183" checksum="8F9A4AF55855C6D0" modified="2022-08-03" version="1">MPSDGVLLLISLGGLSVIVFIILYVAGFFRSTRVVNATPDANAEDEVLKAGGRRATGGLAALRKRKEKKNARGSEQEQVEEAPGAAAAAPAPAQAEGEEGQQDIIEPRAMTKKELQKEMKRREREELRQFEEQRREEQRKRAEEKEEVLIVDGCCGWKSVAPTNTCGFRVQAFQKKREEEARLEQEQEEAARRLEEEKAKKEQEEFDTWKNMFSIEEQGAKADTDSEESQMLLQQFVDYIKAKKVVVLEDLGSAFNLPTQDAIQRVETLQESNRITGIIDDRGKFIYITEEEMDKVAKFIQRKGRLGLTELSKECNKLIRLDGEKESTTSAVDWLNEVEEQPEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDH4</accession>
    <name>A0A8K1CDH4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW60993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDH4"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="352" mass="38596" checksum="2CA39B7192186582" modified="2022-08-03" version="1">MSQKQSPSRMIILLPMMFLMNKIDFENPVILNSARAAYILCQALSLFLYLYIKRKIELKNDTRKIRIPGVTSPFDQTPNYDELTETTYRDHELAKVNEFIKQTLIGAGISSFIHFKMGVNHVVMIQSVMTPLNLYDNVLIQAYILGKRDGRIWNEKLEGEAIDAPVDGSATDAKKAKKQSGLPAVTPSEAIAQAVAAGSDADFDELWEVVKKNVNATTTDDKWTALMAACGSPVDTDDFIRNVIKAGADVTATDGDGWTALHWSAYHGRPEAAEALLENTPKKKLAALLAIKATDGRTALEVAEGEENSDVVEVIQKFSGSGASKKDESESELRRRKPAANATSTTSVDEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDI1</accession>
    <name>A0A8K1CDI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDI1"/>
    <dbReference type="OrthoDB" id="14535at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20266">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045299">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15841" checksum="BB421E476F24F93D" modified="2022-08-03" version="1">MALRAAGEKAAAATRAGSPGVTLYRYITKQVPRVLTLYDIPMEPAEARLSIQALFRKHADVKDPRVVDMLIKKANMELEETLMQWKQKVHLMTLLETGAKLREEKKAVPLEASFDKFFANVDDDEDDWDDIRDVVPAGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDS0</accession>
    <name>A0A8K1CDS0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDS0"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="427" mass="49457" checksum="D067D4509BB1237E" modified="2022-08-03" version="1">MSYQPYGRVSARDRDRRRAGWDMRFGILMVFPVICLVVVLYEFLYLQQFTASEAQEAAALQEFAATTAAPTQDRIVRLRTEPSVTPSPAPTSIVRGRRTMILIANYRDSKRCSETLRSIFDNAVFPDLLKISIFDQIYLSEGEKPCIETFCELVGEAKCRRSQLVATQIDALVATGPTAARYETEKAITDEDFCLAIDSHLVFVNKWDERLIAQWEATENPNAIITVYPKSTEHLEKRDTEDKVQLMCNSRIETEDADAMIQYAAPIWVDKKDVPKPRLMSQFAGGFNFGNCKQAVDVRNDPYTPYLFHGEEYSRAARLWTAGYDFYVPNDDIVFHWYEKRKVVWERDWGKRYVIQQSSKRRIRYALGLPVTAEDFDRTDLDKFRLGNKRTFEQWKKFSGIDPLAKYLGKDKDQFRNCGVLEYVPYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDT9</accession>
    <name>A0A8K1CDT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDT9"/>
    <dbReference type="OrthoDB" id="77715at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="325"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="234"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="548" mass="62645" checksum="ABA2D17654952EBC" modified="2022-08-03" version="1">MERHWDDAASETHSDDSAARVSDVDRRSFLRAHSRKSIESNPEDEEFFVGDDGMIAVVAIDDRKRIERLKQLLERKERETRQAAEYGLSLLESNEELELQVATLKIQLETETTELAVERDAFRRRHEHALLDIENWKRKLARVEEEKHELGAKLQQVVHECECHNGGVPSTSSNQQQQERIDELELTVAELQANNLSKSAALAVLKKWKAVVEAAQRERADVDAMEMSSEQLYIHKLETDQTQLRQLLEQTKAEETRLARTVSEYDGIMKQMRKDIEELHDELSLKRRENTEQMELLHTAESKCSRLQRELALMEHISYMSVAVIDHDDDDDDDEEDEEDEEDEENNAQEKPEVPEKSKTEGIFEQALQDERRSSRQSGGASVSAAFSSYHAPGGAARVPPTPSSMATHQKLHHYFHLTAQSIIHENDLHELCFNSSSRFTIDAWYREIIDENVPFLEWHSWLIKRISAVAASVKNENFSSKDKRRGSGGLSSPFLSFARRKESGTRAQPSNAVPSPAPATPRVPFSVAHSFFRLLGRRENQSELDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE20</accession>
    <name>A0A8K1CE20_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE20"/>
    <dbReference type="OrthoDB" id="157301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="418" mass="48219" checksum="253D21C2276BE272" modified="2022-08-03" version="1">MSSDEGVQITPLRAADGRGWILEGKTRQADDLKKEYHREAMAAFRLRKKASVEDMQAMRAYLERQLQQRLELRRAILLSGFAEEYGDDVDERFLRFQDAFCALVDEAELYRADNVKLQEQIESHTRLRLLLHFELGLVRLPEEDSSPSSDGGSSPSPELRGFFTYFMEHEPPFYYEPFTQQECDAIVDTGLQVALDLLSAFDNKEHGMQEAHCLGWRAQRSLQRIDIGMGTEGDGPAVSRVRFTKSIQCRKENTESTMESLVNFAWEVTTTPKLYARIHRTLLISHPLQSMGDDREILMRNTPDPTGAVNIRYFNLIERVKDTTTEGHPRTTIHMLIADSPRHQQLRELDQREDVLWMTEGSGFISFTQTSDESIEIDFSHVAVCMNEMQAQYFLVELGAMLIRWENLVMPPRLLRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEG3</accession>
    <name>A0A8K1CEG3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009437</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEG3"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001508">
        <property type="term" value="P:action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537:SF254">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="VOLTAGE-GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="15">
        <location>
            <begin position="70"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="228"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="545"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="595"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW61944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="646" mass="72694" checksum="76EBA5D04AB53269" modified="2022-08-03" version="1">MVSYALIERAIRLDHSVKLPKRFKEYRKKGEKKQRPMPKTRALSYHSDALAMATTLPPTYRAYVYENFGDALQEIKLRSDLVHAQLKPTQVRTKVHSAAVNPADYKFVEIGEAIFPARPTPEAPFRLGFDVAGTVVEVGPSAQDVNVGDYVYGMAYFGTFGTFAEYVVMEADHVAPIPKNMTFNQAAGVPAAALTSYQALVTHGNLRAIRPFPSEVWISSPEVNSMPMSKHERERLLPPLPRPPPSRSTDELPRRRPPKRVTTIRNDIWTVLRYRSSIRHRTGLQRISYLLELCILTLILLNVILAISFSGASNGTNAGVLSKEASDWYETFLLVSTGIFSVEYLLRLWSCVEDDRYTHPVLGRLKWMMQPMSLIDLLALVPFYLEISFEFMVIPSYRGALTLRSLRLLRILSFLRLERSYSALANLRLIFKKKKEELLVVTYLTAVLVLTSSTTIFFIENGAQPTVFSSISVSAWWSVETITSLGYGDIVPKTSAGRLFGAILALWGIILFTIPGAILGSAFIEVMLEKQRQEDEDVFSTAMGVTSEAGGHGQPWSRQASDAESDTPVVRSPTGLTNSQSFRRPSPRVSTALRFEMLNQKIDEMALQQRQLQDQVIDQKQQLDEMKQLMETLIAIARHSERAHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEV3</accession>
    <name>A0A8K1CEV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010807</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEV3"/>
    <dbReference type="OrthoDB" id="2187496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051420">
        <property type="entry name" value="Ser_Thr_Kinases_DiverseReg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48005">
        <property type="entry name" value="LEUCINE RICH REPEAT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48005:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DDB_G0278509-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035464630" description="non-specific serine/threonine protein kinase" evidence="13">
        <location>
            <begin position="28"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="717"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1088"/>
            <end position="1099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW61744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1099" mass="122303" checksum="1047B9DEDFE4BDA8" modified="2022-08-03" version="1">MARRMRRMLAASALVAMAASQLDVTTAFPRQSWQERTGTAKAAAPVPIVTETTAPTTSAETVSVSAMAVASSIAVTGSSTSSGADACAEYNQISSSCGEICPNNGLCVAYRKDGKCVDTDESTCVEQNGCTYECLTAASSEIDEWYTTFYGTPQWDPSQKTAGEVEAIRLIKVPRNITRLSFRAISDEVEDVKGKAFEVEFPDHQVVSNQSTLTQLGLLNIDIAKIPDTVFTGQLRSLVLQNCLMQDIPKAVYDLPKLTMLIVDMNNLTSIPSEVGNLSLDQFSAIENDLTEFPADQISNMPRLRELALSFNQITHVDLEMDNAALEYLEMDGNQLLDFQGVFPRLNTLYISRNQMSSFPTSLRQLPALVELDLSWNLITSDEVNQAAEIWTHPKLNTLYLTSNQLTEFPDLSNIFPVLTHLLMRNNTVPKMEGTISGKLEYLNVRGSKMTKFDASFMRLQYLDLGDNELKEIPALSKISPELQTLNISGNSLTTFHDSSDTLTALNISKNALTSLDLTAPKLRVLDISANSFTKIPDCVWNMNVLEELYVANSTALEPIMFTAEQYAFLQRLSVFTIDGRVVAPSDSCPAEWQAEVHAIKVCVENGPGSVDALSGAGDSNKTSPWSWIAVFLVSAAVGAICVGVFIATRRRRQAQMEKDLTSTAGMMTSMNKTGDLTIGLTSTESNMLNSNMMRSNGLGIWDDEELLESRVDFDSITLEQRLASGAYGEIWIGQYRNQPVAIKKLNDAGKKDRTALTYFVSEVKLFAQLDHPRIVGFFGVAWTSLTDICAVIEYMPRGDLYSLLRTDALTRGNWDFAKLQIAMDTVEALTYVHTLDPKLVHRDLKSRNVLMDYDLRAKLTDFGISRYQSEDMATMTAGIGTGRWMAPEVIMGRSDYDEKVDIYSFGVILSELDTHEMPFSDNEPMSEIGILQSVASGELRPHFTRSCPPAIFDIAQKCLTYNPDERPSSLDVAYWLRQLAPMFQPPVRETEAPRTSTRSGNQYYMTEEAWSSARFQKQQSRSSTDTFQPGMTGSTVDLDRDEDDVRQQQQLVQQQQQPQQQVQQVQHQPQPYQAPPPRPQQLQHHDDDDDDDEPVVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF37</accession>
    <name>A0A8K1CF37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF37"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="45296" checksum="96842657A1503AB4" modified="2022-08-03" version="1">MLKLKARRKAEDVPMLKLHDGEKSAILAEVTALITETMTYERIFRDGAGPLDPSKWKEVKARDNFRLYRERKPSNTVTPFFAGDVGGFGIIEPPTLLSLRDLRPLSNSGLTVCSTTDDVEDIVTSIKQSNVPLLIGEGHVEGSLEDVMYGGMAGDEVSSRLRMAYMKDNFSDTKILATIRASTVDAPFDYVVIKWLAMETSSPIMSSQREFLVIEAIGIAVDAFGDQYGYGIMHPFQHPDIPEDPQITRGLMATAYINREVSADRTHLFVRGFVAPPNSEISPKAMVKLAAASLISAANVADASYAKKLSWLMIQNLKSPPSDHQSSSSTCCEQRSTFAKLTSVNCQACGQSTCGKCTLQRNIVVEMTTTNVKEEQLPFCFACVIKAKQMSPRDVAITALELYENDKPECGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF73</accession>
    <name>A0A8K1CF73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vesicle transport protein USE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009842</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the USE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF73"/>
    <dbReference type="OrthoDB" id="4506189at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019150">
        <property type="entry name" value="Vesicle_transport_protein_Use1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050">
        <property type="entry name" value="USE1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13050:SF7">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN USE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09753">
        <property type="entry name" value="Use1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="33239" checksum="D43675B9E512B106" modified="2022-08-03" version="1">MTTAMMAQVLEAERFVRAWKRFRERFPEEEVDKEQKALLRQYVTTAEFLYQSIPHTETPEQWQDLLYLLNDIKVQSGLLLTKRCAMEEAPSCVVPRSKEIFRRRRQREESRREVEANAGIADRVDEPIEEESPEQPEVDLLQFSPDDFKSMLEAKEDVEEKLSTIEIRKRLGLVDRAAADQVTSSSESQSREEQENIQSEMFNLAKQLKETTQTINQSLVEDVKILDAVGQSAESNTEHLDRENEVLKRQLASSIGLWTSVCLVMGAVVVFMATYIYMKLFSRRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFR8</accession>
    <name>A0A8K1CFR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_009701</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="780"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="905"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="930"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1013"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="138"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="468"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="788"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1107"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1343" mass="149068" checksum="37E516D1D9BEA3DC" modified="2022-08-03" version="1">MNKSPSSPSVAYAALPTSPDPSKSKPSLVERYAQEPPFSQRPHPLETASVLSHYTAQWFQPLLTLGANKILEKQDIWRLCAKDKCDVLEPLFKQHYGSTRVSETEGAEGSGNWWSSHFGRALLRTFSRDLIQIFFDHAVYVVMTVLQSFLAQAMLDYLNDRENIFHISSGVVLVVLMTLVSFIGLTWLNHAHFVSSWVGANMRSIVMDQVYQKALRLSSASRQKYTTGEIVTLMSVDSERVFNSVMYGTWAVSSPITFLITIIIIAALYGIVSAVAGGIVLVLVLYVSINLGGRIGQVQSELLSVVEERVKITSEALQGIRVMKFYAWEDSLAERVERIRKVEIGLYRRFHYLNVVNISLLFLLPMIVCAVIFGIYVAVEGTISVTDAFVMIAMVNINRYAVSQFPLAVAALTQVKIAFQRLDTYLGSDSLDCTTTNAGVPSVDKGSIVVRNGHFVWTAANTTFLPELRVDEMNSSMVEATSEDGSSSLSEPLSLFSLEGTNLEIEPGSLVMIVGTVGSGKTSLLNALLGEMKRMSGVCDVNGDIAFVSQESWIRNASMKENILFETPFDVQRYEQVLEATQLALDLHALPNGDQTEIGERGINLSGGQKARVTIARAMYRENYDILILDDPLSAVDPHVAHAIFNECIVGLAKDKTRLLVLNSHYDLLPHADKILVVQHGRIVGDGKYGEILAQFPDLGVQTQKLNSAEEDVIDEHESTIAEHTKTLSADNCTSATPTVDGSDEEPEKDTTVHLISEEDRVKGRVSCQTYRTYFNETGFNGMVVVMALFLVFCVAQALKIGSDWWQGYWAKQMPRKKTDPEYADDWYIWWYIALIVASVVITPVRGVLLTETCMRSAHNLHDELFRRILNAPVNQYFDVTPVGRILNRFSNDLDQVDSNLPQQYLSLLQGVSIVLGCLVVCGIASYWIALSYIPMIIVFIIIGFYFKRTSREIKRLEGITRTPVFNLFDETLGGLDTIRAFRMENTFIALNKTTIDENATFYFAYWSAGRWLAVRLDWLSVIVIFVVSLSVVLSKGSIAPTVAGLSITYSLMLTSMVQRCVRAADLTDNAMTSVERLLHFRTIPAESNDSDCTPINPEAWPSTGSIQFDNLCLKYRPELPLVLRGVSMDIAGGEKVGICGRTGAGKSSLMIALFRITEFESGSLFIDGVDISQLKLRELRRSLAIIPQDPVLFSGSLRENLDPYGDYSDEAIWNVLKQVHLADAVTKWGAGLEFIVSERGDNLSVGQRQLVCIGRALLKDSKIVVLDEATANVDSATDNLIQATIKETFRHKTVLIIAHRINTIMHCDKIAVMDAGKVAEFGSPAELLRQSDSIFSSLTNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFS6</accession>
    <name>A0A8K1CFS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFS6"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05236">
        <property type="entry name" value="FAR-N_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09071">
        <property type="entry name" value="FAR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033640">
        <property type="entry name" value="FAR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF17">
        <property type="entry name" value="DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03015">
        <property type="entry name" value="Sterile"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="641"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1206" mass="135788" checksum="F730580632AB9A61" modified="2022-08-03" version="1">METKMAATFAGRRVFLTGGTGFLGKAVIEKVLRSAPQVEKIYVLIRPRKGVPGDVRLEKEIINSAIFDRLRRERGAECTAFLRSKLQAVTGDVTQSTLGLSPEDQRLLKDTVDITIHSAATVQFNEPLDVAVEMNCIGALNTLAFVKSCPHVVCHLHVSTAYVNSNLRVLRIREELYPLDFDPEEAINAVVNASPTELERLHVNLIGTYPNTYALTKSMAEHMIVKHAGDSLPLVIYRPTIIGASWKEPVPGWIDQIAGAGAIFLAVGMGVLTILPGDPRNVADIIPVDLAVNNLLMSIAAMVSRVPIPRPFIVHSGTSDPRQNPLRWRVPCGIVPDYFRKNPPVRGLFPSKFQMIPTHQQFQVQWFVSYALPSSAYSTLANKSSNAHHMREAARLWQLTWRARTLVELFKPFTENQWIYTADSMDILKQFVSQDEWWIDANEIAWERYIFNFCVGLKKYMLHEDVIDVDIEGVTHTELALSTGRILAWDPDHHAISFPGLLSDVSWAYTSSRKPGYTKSGLLGRFMGVTGWREGINHEASHVPRQHVDSIGGVRNAVLEAEDVRAAISELAEESGRSEQEVEEEALKMLDTMAAQIDYRSVRKVGWMLRKVFRQMYETINVDEKGLIQVRELLRTRQGSVVLIPTHRSYIDFLLMSYLFFAYNIPVPYIAAGNDFLQMGAISRLMRESGAYFIRRSFRDDPLYAKIFEEYTKYLISKGHTVEFFIEGSRSRSGKQLNPKFGILGAVVDCLLSGRVENLYVVPVTIDYEKPLEVMLHQNEMVGEGKIKESLGALLKSLHVTRQNFGSISVEFATPINVRDYAQAMIASNSPSDLLEIDAATRQDLVRDLAYDITDAMIGSATCTTSHIVATLLLIYRQGISKAELVKQTDWLRLEILRRGGRVMGTQGRSPAAIVDHALGLLKTLIVQRRKDLVEPAITSREEYPNMIGLGYYRNKLLHWFTREGALACSYHALDAFSPASDKASSSSPRAGVRVNELLDGAGFLHEMLQLEFVRKDTSKDRFHLENALDGLVAQQVLRRSTIDGADAVVLGDSSRRPLFSLLCMVIWPFVDSYWVAVKSLFGLRGRTEISAEDLVKRIQWLAETMYHEKLISFYESCSLETLQNAVAMLERWKVIERFDKKTGKKSAVGMIRLTAPFERENELETLALRVSKFRKLPHDALHTQSHRDYAHTSHLISQLPALSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGC8</accession>
    <name>A0A8K1CGC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGC8"/>
    <dbReference type="OrthoDB" id="75169at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="78706" checksum="BD2FEC6AD23E3065" modified="2022-08-03" version="1">MRVSSGKHGPKRVKKARGGASARQKMRTTSRGKNSTGMTMQVAKKRRMDDAAAGNNKRMAHGPRLDFLDDFAAMRSLESGEHASRLTEVYEWVGDAVIGELVARCLLSQFHSAPLSARVFRNLRLGAVTNQNLAAVYEDMGYQRRTFEARKRKMKEKADIVEAIAGELVVRLEIQKSDDRMCSQLREHLDGIVACMLQQHFGERRRVHQRAVLAGPLQESFNAFACLPQEHLDEETGELVVLDGAMNAFEEQIARDSKSEGSEQKSFADLIEECAFDDKHVRSEATATNSFHGYAGDTSAAPLDLGDVLSAFEPGLQAVVASICRHIHAKLRLLSTGHVLLESREIFDVFKIYGMTLLAERVSLALAFPSLSARFGKLSAVSLSPSSLTTQRQNVLCMSNMAQCAAMLGIGNHAAASSLDRSQRWDEDRLLANSLRAFVGYHSAIAQENEAASVADDVAFLLQTLAQSDHSSRYPAQVPRRETLRVLPSAVRVTGEFMTSRVCDDLHQPGERPQAPSAPTLVLRRCDSDTAENLFETLAKQQAQREQQARRKSEDSSETFARRRKRKRSECDGEDRSNMSKPSANLTRFTHRRFLFCLEELVVLFAQRKTEECRVKMTAFESDLEPCAGEFFRKWEVSTSTLTLAMRDSFYRLLLHDLCHFHELASTSKNTRDGTRITQLRLPVHYTWAKVARRVTVEDEATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHH4</accession>
    <name>A0A8K1CHH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005494</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHH4"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="24"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18261" checksum="7B129B5A9F2844E0" modified="2022-08-03" version="1">MAEPHLKTAGVAQYIRHQDDVPVNAITPSEEVTAEFKQLKMRRKHRFVLFRIEGAQVVVDGVGAPTSSFNDFLNALPDSECRYAVYDHEFITGDGRKSSKLFFVTWIPQNSHPGFKMAYTHAKSTIRAVCDGCFDVNAVIKKEVEQGMGITNADGSDSDSEFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHV7</accession>
    <name>A0A8K1CHV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHV7"/>
    <dbReference type="OrthoDB" id="186786at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="5">
        <location>
            <begin position="98"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="43127" checksum="CA3D6780BDC9F71C" modified="2022-08-03" version="1">MAKVTPLGAGFLATLVVTGWLGVSLVLTPFFLVAVIPLPPVARVVQPIYRRVTHVVQYLWMTNVALMLENVYGIRIEILGDVATQAAATAGTMNGERALWISNHRTRIDWMLAWSMAVRLQVLDRLKIILKAPLRKIPIFGWAMQHFLFIFLNRRWADDQVMLKEYLPFLCEKEKGASFLIFPEGTDLSDQNLVKSEAFAEKNGLEKRQYSLYPRTTGWTFIFPQLRANLDAVYDITMFYVDYTPNERPSELSLLSGRMPRTLYFYLERIKVSELPSEEKELSTWVETRFTQKEAHLKAFYEENGKLPDGAAPLSTPDMTRPFALVVAFWGIFFLLGCQWAWSWGIISSLIFGVLIIFGYGVATIFFGGIDGILRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHZ5</accession>
    <name>A0A8K1CHZ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHZ5"/>
    <dbReference type="OrthoDB" id="74570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14874">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="106" mass="11338" checksum="C42D865E1865304A" modified="2022-08-03" version="1">MELSPPQITLGAIEAGEVYLFPVRVRNVGSKQERYRVKYVSASAGGHVARIAEGTYDKETARLAPGLAAIVTLTLSFQHRGHITGQLCVDTEGVGTCELAINGVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI79</accession>
    <name>A0A8K1CI79_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI79"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477901" evidence="1">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="112" mass="11056" checksum="02B9A2998017EBDB" modified="2022-08-03" version="1">MTRFFAPLLLLAVASVRADIISDAVSGALGDVVDSANATVNDAMDTASDVTSVIEGGATGVVNAASSYASDKASNAVKDAFEPFVPPSSSSPASISIVCVAAATVAVGFTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIE0</accession>
    <name>A0A8K1CIE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014251</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIE0"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050120">
        <property type="entry name" value="Adenine_PRTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11776">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11776:SF7">
        <property type="entry name" value="PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="41"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="21856" checksum="7F9881F2D4C1A583" modified="2022-08-03" version="1">MTSLNLDDAADYHRAREQLTKVIPVVPFKGVDSFFDIGGLLANPTELQLCFDLFRHAVAPFIDEIDAIGCFDARGFLFAPYLGVLFQKKVFMLRKPDKMPSVSDTIEYFKEYQGDNATGGDHLSIQAHAITKGDRVLLVDDLLATGGTVEAGIRLVQQAGGVLSACLFVVEIAVLNGRARAEKVSTSSTRVISLLTEKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIL7</accession>
    <name>A0A8K1CIL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIL7"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000192">
        <property type="entry name" value="CTD small phosphatase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="10">
        <location>
            <begin position="162"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="337" mass="37479" checksum="82027590FCB69A22" modified="2022-08-03" version="1">MMPVSRSKSQNANASTLKSETQQQKSGGLFQTVVFSRKNTNHGPNADLATGSPAKKSLGDLQVNPLASVVHQADRNGRQNAIVANGRTSQTRRLTREEGEGGSFRNLFANIWSALGISEQQQQAQAQKNSTTKPGTAPAGKPNASRNVVELRKSVIPPLAPQDAGKKCLVLDLDETLVHSSFKPTQNPDYIIPVDIDGTIHQVYVCKRPGVDEFLVDMAKHYEIVVYTASLSKYADPLLDQLDPHNVIRYRLFREHCVQYEGNYVKDLSLLDRDITQTIIIDNSPMSYLFHPRNAIGCSSFIDDLNDRELDSISRFLAKIRSAEDVRSELHTWDATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIL9</accession>
    <name>A0A8K1CIL9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gametogenetin-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIL9"/>
    <dbReference type="OrthoDB" id="2422440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026073">
        <property type="entry name" value="GGNBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13601">
        <property type="entry name" value="GAMETOGENETIN-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13601:SF2">
        <property type="entry name" value="GAMETOGENETIN-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66716" checksum="CCDCD54C2F39878B" modified="2022-08-03" version="1">MMDDGIRVRGSDVVVPMEDALFVDEGHDGWNVCRASQRKSCLLDAPHQCQCQPSAAEAREFRKRWMFLTDAERTASLRANAQQFLQTATELLPCLGCRNSTEALFQRLLSGAGSPPTLIVNSGLCFEKDKHFRLGDAHMTSSDGTLALFLHHERYGNTSLAKYSRPSKVASARVRCPLHSQRSRGRPRPAAFEALWNKLPEDQRRHLSHIDSEQFLTDLENYLRRHRFCCRCKEKVLEAYDLLIGSSCSEDDCEDCAGFDCGDKHHDRGDYGDELHYTSYLFDELTYSRATSHIVVPCHIDFMSQLMSRADQEIVGDWGDRHARTIAEAQDEVLTCLGIVIWEKMQNLWTKARTEKRSEELLVHCAVSTLRRNFDVAVEALHGKEMMEQLLAEEDDESRRLAKKKEKRKEKKKKRKTKQKQTTTESATVASSATSKKKKPSPSSTSSTAKTFAMSSPSHSLSSNDESNNQSDSDSDDDDDDDTTQSNAGEHQCTANCDEVCTCKQLLFDEEMERQLLSSMGWSGSNQFGSSMLDLDVDTDDEHHGIPEDEIEFWNRNRSALVSKRLAQRQKLQEKFDQLVLRSSSLAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKU1</accession>
    <name>A0A8K1CKU1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKU1"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="275" mass="29134" checksum="42186ACDEB2B67B0" modified="2022-08-03" version="1">MQLNELFNVKDKVVVITGGGRGIGKMMAEGFVKNYAKVYIASRSLKACQETADELNAFGAGKCIALQGNLTTEAGCKELADEIAKRETKVDVLINNSGVSWGGDIHNHPGKAWDRVLDVNVKTPFFVTRDLLPLLDAASTSEDGARVIMVGSVAGVMPQNIETLAYDTSKAAVHHMTRVLAAKLARRPNGGRILVNAIAPGLVPTKMANGIVHVTGSSYEQLEQFIPLGRAGRPHDMAGLAIFLASKASSWITGMIILSDGGHVSAAEAVMGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKY1</accession>
    <name>A0A8K1CKY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKY1"/>
    <dbReference type="OrthoDB" id="110429at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="51937" checksum="7139A91340B97900" modified="2022-08-03" version="1">MSMWFSGRDLETTTTKAKRVFFDENDEDTVTHESNGFLASHRNSLTLGRRSQRGSRSEVLVLDDTDEHIPEPVMTRTAVSEKPSLGLTDTRAQSMQRNPIKNGKEDELARPDLVAQSIEVTVKATGADLSEQEYAHALIREYLQAYYPRNVLEMFDKEKPATRPPDTASIDRIHRRVVGTGDSVDGQTKYEQLLVVWDKAVHRRTLKTCPRSKQAPDESGSSSRTKSKTKSTSSRKKPALTVSTSSDDTTEASIDFNRLNHPGHTPKADSSTLASVIGEPGSTPKASASELKALGFADIDDISTSSDATGKTDEDADDDGDTDSELSNYAMRKRTAKKHNKRVNIGEPGGTPRKEYIFFRETPPQFVTETVEEAEQILRTIVGDDTFRRRLQPTMSAKAERFVELQSSDVAKYTIGQAVDNLGAQRNICGLVSKLYGSRQCGSSGPGTIVIDTWYGSDTEPTSGAEDDTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL99</accession>
    <name>A0A8K1CL99_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL99"/>
    <dbReference type="OrthoDB" id="162989at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="187" mass="21604" checksum="CABD4A213E48B31F" modified="2022-08-03" version="1">MEDTNMTPAYAQQISQAEYDRQTVEYTTAAIEQLNEDVRNQPSVGAKSRFFQDPANVQKGLPVFQGKHTRFVYDDEEEEIVEAVDVTHAPIPGPQVRTTEDLDSSDEEEEEHEEEYDEEDDYEEEYEDQDDDMGVENEFYHDEEGDEEHDEDGDVELDLDDEHLQNLLQNIAMELADVDLHAPDAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD2</accession>
    <name>A0A8K1CLD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD2"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000072">
        <property type="entry name" value="DnaJ family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="39417" checksum="70D3487B939A1502" modified="2022-08-03" version="1">MGKDYYGILGVSRSATDEELKKAYRKLALKWHPDKNPNNKEAAQEKFQEVSEAYEVLSDKQKREIYDRYGEEGLKGVPQSGPEGGEAHGFPGGNANFSGFSNFPGGRSFSFNSTDPSKIFEQFFGTSNINEAEHVDPFAGMFGGFGGFGSMGGMGGMGGMGGMGGARPGSMHDPFGNRKRPEQLKRHLECTLDQLYNGCVKKLKITRKVAEPGSNQVREEQKILEVSVKPGWKDGTKITFEGQGDALPNRSPQDIVFIIKEKPHDKFKRDGDNLIYKAKISLKDALVGNGTLTLKSLDDRSINVRLDGVIAPGTRKVISGEGMPLQKNPSQRGNLFVEFDVQFPTSLNESQKSLIRQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMD4</accession>
    <name>A0A8K1CMD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMD4"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="24511" checksum="D26DB2B2F7D74A5A" modified="2022-08-03" version="1">MTKTVLITGASRGIGLTFTKHYLQEGWQVIAAARSPANADELRALAPYKIVQLDVADEESIVTAAKELEGEEIDLLVNNAGIFEDESLESFTKAGVMKQFEVNAVGSFLVTRAFVSHLKAAAPNSGLAKVANVSSRLGSISLNQEGGLYGYRASKAALNMINTSLAVDLKPLNITSIVFHPGYVATDMSAHKGVVQPEDSVNGLAKLIDEATMEKTGKFYDFEGNALSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMM9</accession>
    <name>A0A8K1CMM9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMM9"/>
    <dbReference type="OrthoDB" id="526070at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042856">
        <property type="entry name" value="RSP14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599">
        <property type="entry name" value="RTDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="50657" checksum="C78EB3E4A53F6443" modified="2022-08-03" version="1">MPHLFRSYLIEQVHRAFGNRVIPKYAELLISDDLTDEDRARALEELHDLLSSQERKFQAVDREVMFACTDLTESKAVTVRINAARVISSLVLYENYVDELSTDAMLRAATTLLSDGEEDAVLAGCSIFHNLTISNEGSLSLASRMETLTQITSMINSQPLKLVSESLLDAILGILANVTRIYEGAKACAECAITVPVLTVLKKCTLYDAKTVHAATLIILNAATHDHGKRMAIRQDGVEICLRTLTKVLQAESTFQKCEPAMHNELTRCLVSAVMALSTVEEAKPRIVEFGIEPLVTCLHHKDTKIKRNAMIAINSACESPQGIAVFTDKLLAERDLVIEVFGAKCIPALLRHLQTIDEDSTVQVLDILVELCRTEDEAKEVVQCLHLLDTLAELLLNETKDIRNHVVSTFQLLREHGETYVRRIGKKLHKHGVSSGDFELIMGIEISTFESTYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP30</accession>
    <name>A0A8K1CP30_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP30"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004846">
        <property type="entry name" value="PRK06197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="35048" checksum="2C9AB2B277E486E7" modified="2022-08-03" version="1">MASRTPVPVRWDATQLPSVHGQVVIVTGGGTGIGFHTALELARRGAQVIIACHIEAQGRDAVTAITSEISNSAEDKSGRAEFMLLDVSSLASVKAFADEFQKTHERLDVLVLNAGILAREYVQTPDEYECAFATNYLGHFALTAHLMETLKRSEAARIVTVSSVLHARGKFHAGELMMLKETFRRMKAYCQTKIYVLLFTFELHRRLQASGTTNVIAVASHPGIVATNMMATDLSDLGFATQLKFWIAGKLMHGPEFGALPLLYAAAAPGVQGGEFYGPDGFLGIYGHPQHARASQDATSEANARILWTKSEELAKVKFNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP46</accession>
    <name>A0A8K1CP46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP46"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF7">
        <property type="entry name" value="OBP33PEP LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18582" checksum="8776BA154F1A39F4" modified="2022-08-03" version="1">MSTPELYVVLSNTSGKQNVGTYLRMASAFGATQILVVGSQRYGTHGAHRAHKYVNVVHFYKFSEAQAYLKERNCAIYGIRQHDQVDSVAAHEVLYQGSSAFVIDNEIVGLSDEQVAICDAFVLVPFHVTPRTELVLDVAVVTTIVFHHLTRPFKTMTSNNMNMRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPU3</accession>
    <name>A0A8K1CPU3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPU3"/>
    <dbReference type="OrthoDB" id="62356at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="543" mass="62947" checksum="275F07499142D7C8" modified="2022-08-03" version="1">MATRKSSELSRASLTRPLHEEEEEEEERCRASFRTHARMMDVASKALSDPMHALDRSGVSELCQYIQQLESEKRDLQDQVNFHRDQDATHRVQLAAAARRIEKLETSCLTVSDASDIQEESARQLETALNTERERGAQMEARLESMQRKWEDTERARQHAVFKFSELQTTMGEAQMNRLTKPVVPKPQRTDERDPTTGSSERIEKYKREIELLRQKIELRDDQANEKQRLAVELALRSAHLEHSAMLEKVRLECEIKLSEWRHDEAVRAKEIEAAMEEDRYSIRLEMKHGMQRAQIDQRVYYLQAQAAIVQQQNESTSQGTDEEVPFGAMDEVLVRMQLELLRTRRFGALKKLVLIRQSKVDRALRIAVSRWKLHATQIRIFQLNAVLHMHRIVTHLEMRKQRAYFHNWKAHTKLMHLHASQQQAVACWNRMLAVERLRQLLHERTLKQALRAFHRWRASVLQQRCGTATGSSGMATSSTTTPSEQPSEMAPPIPTGDTASASQATVTAGAELQEEIKKLHEQLASSKSEAWRYKRQLLKQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRP9</accession>
    <name>A0A8K1CRP9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PinX1-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012219</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRP9"/>
    <dbReference type="OrthoDB" id="29523at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF31">
        <property type="entry name" value="PROTEIN PXR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="202" mass="21762" checksum="5BFFF9BE7D3BA1E4" modified="2022-08-03" version="1">MAADTEAATASSSNVDGQVMVALGGMQNMAWAADTSKFGYKMLVKMGWSAGKGVGKDLQGQATHVKLERRSENLGVGCSLKQAEVQGWTNTAAGFADVLKKLNKSYGDKRSSGSSDDSSDDDSDSEKKKKRKAKKEKKSKKEKKSKKEKKAKGEDGKKVSSKLTLSRRIVYHKRLRNKNAKSYDAADMSAILGVASSTATVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSH7</accession>
    <name>A0A8K1CSH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSH7"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045595">
        <property type="term" value="P:regulation of cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039680">
        <property type="entry name" value="PLEKHB1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14309">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14309:SF10">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="253"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="387"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="585"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="728" mass="82334" checksum="1688857A416B6753" modified="2022-08-03" version="1">MGLKEWLSLDFSSKRSRESLAAEDARKQQQHPHNQQTQQRAGSYARDSAPPSSSSSSGASYQASSHARRTSQTQGYADFHRPQPPRYSRSDSRQSATTRRSLEYQRGSDYQRPSGVAYRPSTHPTEQYRQPTNPREYYDTHARPSYQNNASTSYPPEWRGSVNNQVDAYDDGEPIVVGGLENVPMPPQVDGLRMRPDARVSQQENEDQPRSSMLEAMRFSWLADSGGSGGRRSSLFARIPSDVQAQLLHEDVEVVMKGWLEKCGQQFKTWNWRFFVLRADGILAYYADEQMKKLKGAMHVGFSSKADVTVQSNLIDKKCVFLLTTSQRNMMISAPSQKAMTKWIAKLHAAGATPSQPWDPSKKTVKFFVRDAECPHEWKRYDDPTSYIHMEGCLLKRGHVNKNWKNRFFRIERGELRYYTENQEQLKGSVPLKGTIVSPGMTQCPDGRKNYFVLTSKDGKFEMHLNAPSEQAMHRWIEALQEAQTALADRGAKGTVSGLALVVRRADEIPLAKMEVVFNTPEEINVELERRMEALVVALCPKGTVPVGSQLVAVGSRSILRQPNVVARQMLRQASFPVKLHFVLPPYKKGELIKKSRSGFENWKKRVIVVTNGEIAYYEQVGNAAAISLKHRKSFSLRGCHLNLIEMPGREFCIAVARSPSDKLVLQTRNEDERIEWASVIYCSIRMVSQGVTPGHIENLQLEVASEREQRAATELLGTFQSEVDVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUI0</accession>
    <name>A0A8K1CUI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUI0"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141:SF1">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37477" checksum="C647C446D9D9A993" modified="2022-08-03" version="1">MWIYPSPSWADEKVRMEQTVFGAFDPSVYAWHCALSGNGNDPSCLALLEFGYIQLVQRNYASTTLVEFKYDLDEYYGKTAAIPDGASVLLISDKLDFQTPPSWAVDQYEQMYSLRTALLTYGAGRAPTALHQAAMRNHEVAELLLQSGVNPNTTNSWMVTALMFGLREERHLEFVKLLIDYGIDLNITDYNRKTALWYASTLVSGPELVRLLMKHGANPMCPESDETAFLASAECGHLEIVEMLMEYVEDSAISPRDFSLLLCRSCRSQRKEHAPIILQLLRRGKAVIPTNYPEILEAAVSGGHYAVVQYIFELDTDTAVPTEVFSRALLHAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUL9</accession>
    <name>A0A8K1CUL9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Golgin subfamily A member 7/ERF4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUL9"/>
    <dbReference type="OrthoDB" id="67682at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="3">
        <location>
            <begin position="33"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="16583" checksum="F98266ADDAA21F71" modified="2022-08-03" version="1">MSTEELLVNAENKVIVLARLDAAGFKTVTAFSSAYDTTFPESLDGIISRKEFKFCIDVINQTLEDYYPCVPCYVCGYLCCLTTFGLSMLMPEPCTKELSRNLDVVLRRLNNREEFLYRGIVWRFHRSPRTHSSWIEICQLLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVX8</accession>
    <name>A0A8K1CVX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVX8"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451604" description="subtilisin" evidence="10">
        <location>
            <begin position="25"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="185"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="472"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="475"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="560" mass="57812" checksum="02935D95C65AB924" modified="2022-08-03" version="1">MVFTKFTQVLALTAAAVAISGASAAPRVDAGVHRTLRQQGTVNLIVTMKQSTKEALSSVQEAEYATRGAKIEAIVNRLEVNAKSSQNELVQLLSQEAATVSGESLFASSTSYWISNQVSFKGASAALLEKLSALPSIAEIREEQVLSLPPVIKSESNSTEADVKANEWGITKIQVPDVWAAGNKGEGIVVGAIDTGVLGEHEALKGNFRGDYGWFDPQKKGKTPYDDNGHGTHTMGTIAGANGVGVAPGASWMACRGCTNEGCTEADLLACAQFMTCPTDVDGNKKDCSKAPVVVSNSWGGGQGDTFYKAAVDAWHAAGIIPIFANGNEGPACTTSSSPGDYENVIAVGATDSSDGLASFSSKGPSKVGGLLKPEVSAPGKDVRSAWNTGATQYNTISGTSMATPHVSGVVALLLKAKPGLKYDEVKAALTSGVDTASLKPAGQTCGGKADGTFPNNNFGYGRINAAKIVTGSSTTPAPTTQTPAPTTKTPAPTTKTPAPTTQTPAPTTKTPAPTTKTPAPTTKTPAPTKPTGCSGLNFTECYYSDNCYWSWAKGVCNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWX3</accession>
    <name>A0A8K1CWX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWX3"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051631">
        <property type="entry name" value="Ankyrin-KH/SAM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206:SF8">
        <property type="entry name" value="ANKYRIN REPEAT AND KH DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206">
        <property type="entry name" value="MASK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20776" checksum="8C31C752D3880375" modified="2022-08-03" version="1">MVRFLLSKDDDDLFSRMENENGQVAVELAVNNRDVKFSRSSHTTEWIISCAISRKPALFEAAKGGHVAVAEVLLANGADVNVPSGHSPATDGYYFPLRAAAIHGRVGVIDALLEHVAHLHDSALSEACDSGHVETVALLFERGATLDYDRRENLMIRAAGVGSVEILEFLHRRGFDVNASDAVREDFCSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC97</accession>
    <name>A0A8K1FC97_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Staphylococcus aureus surface protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="189446at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="68"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="72"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
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            <taxon>Peronosporomycetes</taxon>
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            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="38853" checksum="7586E134445D14DC" modified="2022-08-03" version="1">MRITLDKQIVVVDVSGAVVFVSFLSFPRSSDASTTSTIMSFVFAFDYLPTDVLHELLNCLLGADLFRLAHTSPWFFRLITHDDVWRTRTVIPHLPDLHEYSVKYLYARARATRFQGQCVDPVDQVSRGGGVTVPFVKSYRGPASITIDTWFSLLPPTQGVFPGGVLLGAQSVKLSVERWPYYHQQFIHVDMQGNLYCTLTRQIKEPVASDLQYNRWYHVALSYDGSTQHVYLDGKVVSVETAALNREWHSVRYVQVGSGCISAGAIGKPTEEFCGWYGFHGVIHEFRLWNHVLSAKEIDSLANGAALDKIPSFSLLVDQDSEVMGQVKRIRTSSPLERVFTVLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDI7</accession>
    <name>A0A8K1FDI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010518</name>
        <name evidence="10" type="ORF">Poli38472_010519</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDI7"/>
    <dbReference type="OrthoDB" id="10051896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035645301" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="53"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="282" mass="28806" checksum="3C0611AB713FCF92" modified="2022-08-03" version="1">MKFALIAAAGALAVASASAQKPLSYAELLVKSEIAATLAKYGETEEGAIKPLIVGGTEVPVGEKLWTAGLRQTATGSDFCGGSLITPKHILSAAHCQGYGKYAAVGTHYLSGSKDGERIAFSKEIIHPKNNADTMTYDLMIIELASESTVKPIKLKIAEPAVGVTATTNGWGTTSSGGSQPSGMRQVDVPVVSDSACAAKLSIVAESMICAGGVKGKDSCQGDSGGPLTVKEDSEDVLAGVVSWGQGCALEGYPGVYAQVSAAKEWIDSTVGAAGYNATWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDN5</accession>
    <name>A0A8K1FDN5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDN5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="106" mass="11802" checksum="77C8EB4553823483" modified="2022-08-03" version="1">MTRSPDNITKIEGYHAAAEAQIKCEVLRRAGLPEPADLLKAADEELYESGKPIADAFETRMREVIEQQGIDEVENAIALMLYSGDRKFDETILALIYLIFGGAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDN8</accession>
    <name>A0A8K1FDN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDN8"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="46"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="552" mass="61227" checksum="C5DCD14CA1999384" modified="2022-08-03" version="1">MATLFTNGKIWQWTGEYAAWMHVDADGTIKQVGAQETPIPADPTAQVVDLDGALVLPGLHDSHIHAYYMGESAEFLNLSGCSSFEDFNERLRQYDAKYPDKSWVVGFGWEQDTLSASARYPSRHDIDAVVRDRPVLLHRACWHIAAVNTKALEIAGVDITKKTHDLASGTIDVDEQGATGILREAAVELVTKHTNEESDAVRIKYLRHSLEKCVSHGLTGIHTNDHNAWHLYSQIQQESGLPLRVYLTPLIDELKNPSTPKPGSKVGLLSCDRMKIFSDGSLGAETAALRTPYLGTSNTGILMDTNEALIKKVSDAHKDGYRLEIHAIGDRAAEQVLMALKEADVPPEKRPIMTHCQILGDDLLTQMQTQGVIGNIQPSFTITDAAFARKRLPESMIKYSYCWKTMMQRGIVCAGGSDAPIETCNPFQGMYDAIYRAKPTEPDQVFLPEECLTFEEALEIYTKNGTFAAMADHQLGQLKPGYLADFVVLRRDVTQDHKAMLDSDLVHSVWVNGKKTYAYDPQRAANASATDFSQSSLPGKNGQIRICRCCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEH0</accession>
    <name>A0A8K1FEH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEH0"/>
    <dbReference type="OrthoDB" id="185462at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="482"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="627"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="826"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="834"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="849"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1100" mass="124147" checksum="E828D0C3EFC8DC36" modified="2022-08-03" version="1">MLRTLANWKPVVQQTESERYQVSFALSDASNGPSLKLGAANKRLKEALIHGEYQLALTEWEALLSQAPTTTHPIARTTYDQLLFEWNRLGMEQKMAKMSKPMDLELMLLLLEELVVLKRVNARAFNTALVACNKLNALEVGLRVLQLMKTAQCQPGVFAYTNLISCCARQAKQHKRRQDVFVQHAEQLWQEMIDMGIEPRIEVVNAMLYVYRAAKNRSMDADALVAKAVREMKLVPNGSTIATLLECMLKDGTSREATRWLEYALRHQIEVEPPHARVLLDFLRQRKSWHRCNNLVALLKARGLVHQDQVMKQTINYIRKRNSRSLVLQAINTGVLGKDQGVGPRVRYSRDLGGLVRALKQGKHGELSRVPKSELEKMIQSGSTKDIVTLILLMHSVQLEGALPDASGKKQWTQVGLQSLANARCWWRATEIIQELVKQRSDAELDIECFNSALAACTKAGRVEEASDVLSMIEQAKDVVPNRKTYELMLGCYAECGDADAALRCYQKMNQAGFAPTVINLNTVLKSIAVAVQQGLTEASSHEREEASDQDLGRLAVQAAHHFRGAIDNHDIQPTQTSIYFLFRSFLGAPAAMEDDEEEEGISQPSFQHIMHMIQATCRDAPLEMLSPRAFNVALDVLQRRGDANACFEVYNTMISRGYMPTTDTIRLLFDVCCHSESAELGHLLLDHLVSELELEGDSKAILRRTIAQEALRWAASTDAGVRDQVVAKLTEAGLPLNEEGYERIIGMYGLQGNISEARKLLHEMLEKLGYVTTDACNRELQACSTAKAPVAALDTIAWMKRQRIEPDIVSFNTVLSAIRRGITRPLSHAEDPNANEEEEEEDREDDEVQQRPEQKPRNRFLELEQNVSSVVSQLLEEMKQREVLPNELTYSNIVALCASRGDVDGVLAIVDEAMHQSQVHRTDLSELLNQTSLTGYLDACAAKKSTDRIKALHQMLEQWRREQAYHIPPAIALKLLAAYDAVDEWRSPLSLVKDITRRFGLQPSVLFFRAVMSTCNRVGKYRYAEQIFETMQKPGAYRVYPDAESYVEAIYACEQQEKWPLATDLFMEMRRKCADEDLPPSLLNKIALGRYSEGRRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FER0</accession>
    <name>A0A8K1FER0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FER0"/>
    <dbReference type="OrthoDB" id="90188at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34291" checksum="048D96D1602F8481" modified="2022-08-03" version="1">MSTRVGCKSSSQPWFATQFTCTILEINCYRQGISDSAHEIDIALRRVNPDGLNSLIISHCPALSIPPRIQELPYLDALEINNASLLKWGEDAKVTHSTMPALQMLAFVRVNMTALPDAILTSDLSHRLRDLTISESNLTTLPPDLAIKWRRLFDLFIERTRVEVIAPTLAISSPMRLSLMGNQIHELPDDLFVHSQFSVLSVAKNPITKWPETIGNLDYLTMLLLDYTEIEELPSWLLDEGQHRGKTGKIITVSAGGSAYCRAKSALPSFSAVDESNTGLRVECRVKPEEEYEAYPLSYNTRHRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFK0</accession>
    <name>A0A8K1FFK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFK0"/>
    <dbReference type="OrthoDB" id="116005at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="434"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="718" mass="78231" checksum="3A616AA53442299C" modified="2022-08-03" version="1">MATLNADLTDSSYVCPSVDTFTTNCKDAKGQIAYCIVKPTDDSCELISDCRPTVSDPTYSSITCDSMYAAQVDSVPASTTSLNLGFNALKEFKPTYTNGTSKLIDLRMVFNFFEDMDDIELPASIQSVDVSRNYLRALKFSRGFSSVIKLAVSHNPITSVSGNALGLADLEAKNISLATLSDLKLPSTVMNLDVSGNPNMTFNNFTSPSDLRTFVAIDSKITTLETLDFSPSSSLGTIDLSGNTISSIVGVEFPPKLRSLNLNGSDISCFLVRESDVSTLTGLSTFIVSSISQDGCDSAVMNGTRPQPLTIADKSYDFSVIGDAEFTSRYFPHKVETTPPPLPAPTPAKSSSTTIIIVVVVVVVVLLAGIGFFFYRRRRSRFHKSMTYWNLSTPTPQTGTTTGTTASSGSIGMPVNDIRHDPELVKRRVPQSSIKRSRVLAKGGFGIVYLATFNDREVVAKQILPEKAKDSHAISRFMDEIRLWAKLNHPNIVQFLGLSWTTLADVTVVTEYMSNGDLAVMLRSQAAVSRHRELFTWTKSAGQIKRNKLELAIDIAEALVYLHGQSPSIIHRDLKSQNVLLNESCVAKVTDFGISREVEDYMTAEIGTVAWIAPEILDGGQYTERADIYSFGVVLSELDTCEKPYASGIHTPTGEFIAKVPNAHIALAVSDGSLRPSFDNDCPRAIRAIAQRCLKGNPRDRPTAMEVLAELCALQGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG43</accession>
    <name>A0A8K1FG43_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG43"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="37774" checksum="079118BF2A0ADF58" modified="2022-08-03" version="1">MTHHRRRRHRHRHSDNTDRPDEERSESQYITPHTVEEEAEEVNVDVDVDVDVEEDGEEEEEEEEEVSSYGFFPVQTAAELVRMLEAINTNMEFEVATIQNDYEEYVTQRGTEIASMDRILLRFELKVDEQYTTVARTITEAMGYTIEGMGDALVRFELRSLAGSGEKSALTMDEIERIKDCVEKLVHLRQQVTGSTTPTAIKESRISFFNAAQVQAATAVWAFTTGPPDMMKTIDAHLKVELAQTKCNILHRAGFTVPTDLLEAADEEAYENGILISDAFDAKRNEELDQRGFDELEIEIAFALFLDLPEFTDATVAAMRILLGETDEDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGF2</accession>
    <name>A0A8K1FGF2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGF2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="125" mass="14049" checksum="3140AFE7E08D5B4E" modified="2022-08-03" version="1">MKRHDEDEGDALSRKKARVLKHKSALKRVEKPLAPADACVGVVVLGNSTLLRHVTSFLPGIPHRLLELEVNNGVTMDARRKANKAVRDLDGLNMYLDRETPQVKSLIENHRLAYRSLTDMAIETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH27</accession>
    <name>A0A8K1FH27_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH27"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="47555" checksum="FFD23F29D396D051" modified="2022-08-03" version="1">MAMLVTANTFQLALLLDSVVYTRAFITKMLTIGSPGLFVGIITSALHIPSELHYFSFKIFGLTMDGMDLLINGNVTIAYFTGVKVLRSLHFVLRKGKVSDVPCEMYFPLCRLVSRTEHLERQRSHTAPPSRGPYQQELHLLRTEEFRVIDARLTLIPARLRLRIPGIVLNNIGYVGVFSSTVALIWHASNFKADPTKPQVVLAVIGLASAVIVFVAYIPHYQRVLFRRVLIEIDSWFISFLFTTVTFGACDIMHWDTRVFFLVPAWIWCHWTIFLDALPPITRTRLQFQRRFALVVNSALFFFPLVIGYWIFFSKAPKMQNREMLNVPLGSFTVRMEMYSFLASKLFTMWVWTGRFLWRERFRPHDAFKLIKHRAQYRIAPPTAPPIAQRAVQPQLRRAWASVSNLHRKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHP4</accession>
    <name>A0A8K1FHP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_014227</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHP4"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000007">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="12">
        <location>
            <begin position="86"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="709" mass="79023" checksum="E99E801789615517" modified="2022-08-03" version="1">MMNRLRALRVGAPASAAVVGALCGGYWSDRHRWSEARAEAPGPDDRVFKGVEEKWYPNITTKHWHFYRGKMNPNAAKSLKLFKCADTPIADEIANYLGVKVNKMHVKNFADGETSVLVDEGVRGHRVYIVCSTTNVDRLMELLLSISAMRRASAKSITAVIPFYGYARQDRMHKGREPVAAADIARMLEVMGVDHVVTVDLHSAQIEGFFKPEIPVDNLQAYPVGAVYFSEMHATNPIVIAPHSSAVNRAVLFRDILSRTIDEFVPLAFVVRKHRLDDKLPGELVGEVDGRDCIIIDNLVDTGSTLVKTAQVLKSHGAKSVSAFCVHGRFSGEAAAKLQECDELDLLVTTNTIPMDKSTRGATSKIVTLSVAPFIAEVISCIHTKSSIIQIVLTRSDSLSMLMTRGGAMRALDGAARRLLRPNGPTSARLISSYPQPSPRVAIPALRVVYPIGIRGFASGQSRGDVGYELLKRDFRRWLRKEVALLTVMIVAGVSGVYIYQNRENAPSRQVMRQLDLAAKSAKDDDRETALKHCLQAYSITKATNPQDRHLFELAFAIAAQFETLGKIDSATRYYLDAVGALPYVRDSTTRERSRLVVFDRIAQCYQDRGERRAAENYYRQAMDCYESHIRSRSKDEIDEQMKREIPAVLFNYGQFLTHQRRWADALLALRLALQLADAADVPEENKQLIRKLLESLEVDGDDGEDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHU3</accession>
    <name>A0A8K1FHU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012897</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHU3"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14376" checksum="142868CB0A4E46E3" modified="2022-08-03" version="1">MGGPSRPKKGAHAKKTKYKRSHATKCRGRDIDQIQDDLKLEKLSGKAMSFEVDEDLPGLGQYYCTPCGRHFIDAKTRDVHIKGKLHKRRMKDVAQEQYTQAEAEAGAGRSVEKYVPLRSKEVDMDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIN9</accession>
    <name>A0A8K1FIN9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIN9"/>
    <dbReference type="OrthoDB" id="165494at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="17862" checksum="40DFDF2B00F745AF" modified="2022-08-03" version="1">MRRSARKQHATAVPAEDVGKSKAKKERKTTKGKRKSRDEESEPHELEETQTTPRTSETSGVSVVDGGASVSAYVASCREKLHVLRERKQEQEQRTEVIVQETFGQIEAIINALMTTVQTGYTSARTHFDETSGQLEEGLDVHEQVESKLHAITAILLGSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIY6</accession>
    <name>A0A8K1FIY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apolipoprotein D and lipocalin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIY6"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463441" description="Apolipoprotein D and lipocalin family protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24977" checksum="46D34AF389D1F695" modified="2022-08-03" version="1">MRGLFNLVVVAASALVASASAQATTCPPADYRSKAVFNPAKYFDGRWYAIQQIPVTYQPENELFCVTADYTIETTKLCQLFRCNETVVRVDNGANKDSVTGTRKTAGLNGLIKDLSKPAEASVGPRFLPSLFYGPYWVIEAGSYDELLADNTEFTSENYEWAIITVGAPEVKTSGGCLPGTGAFNGEGFWLFSRKAVVSQDITDRLVKLAASKGLDVTALKIVPQEGCKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ07</accession>
    <name>A0A8K1FJ07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013033</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ07"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="16"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="37064" checksum="9A952B8B0CAC938A" modified="2022-08-03" version="1">MAAEPRTVRAFAAMKAGLTVETWEYQAAPLLPLDVEIAISHCGVCGSDVHAITEGWGPALGANNYPMVPGHEVIGTVTAVGSAVTDLKLGERVGVGPAVGSCGECSECIQGKDAYCPKGVFTYNGRRPDGSITYGGYAEYMRLDSRYAFKIPEVLPSDAAAPLLCAGVTVYTPLREHVKPGQRVGVVGIGGLGHLALQFIRALGAEPVAFSQSPNKEEQARELGAVDFVNMANPAAFGKAQRSLDALIVTADAKGQPYDAYLSFIRPHGVFMLVGAPEDNFSISPFSLLASNVTVVGSLAGSRRDMKDMLALAAAKNVRPVIQKLPMKDANKGLQMVNEGRARYRVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ15</accession>
    <name>A0A8K1FJ15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ15"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="56"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="249" mass="27127" checksum="33761F43D2B62188" modified="2022-08-03" version="1">MSPAYASPSPMAAVWDRHAPMYEQVFERSTSLWGLDALTLASIPDIQPGQNKPRFLDVGCEAGKFAIAVADMGYDVTATDLSSGMIERLKNKAPKHSHLTLDTLATDGQTLEGLSDNLFDYVSSIFGLTMFPQRELAWKSALRVLKPGVRHDMSFKSGEELVTGMFDNGAMLAVLSQKDVESIKLTALHYFQQIIDGVVPFSPSAKPATVDPASSPFVPRGDSRAEDHPIWCRAFSFPAIGHVALARKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJH9</accession>
    <name>A0A8K1FJH9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WASH complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028191">
        <property type="entry name" value="WASH-4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028283">
        <property type="entry name" value="WASH-7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028282">
        <property type="entry name" value="WASH-7_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027307">
        <property type="entry name" value="WASH7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31409">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31409:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14745">
        <property type="entry name" value="WASH-4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14746">
        <property type="entry name" value="WASH-7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14744">
        <property type="entry name" value="WASH-7_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WASH complex subunit 4 N-terminal" evidence="4">
        <location>
            <begin position="212"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="WASH complex subunit 7 central" evidence="3">
        <location>
            <begin position="824"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="domain" description="WASH complex subunit 7 C-terminal" evidence="5">
        <location>
            <begin position="1214"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1327"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1400" mass="160698" checksum="FDDB07279C321D80" modified="2022-08-03" version="1">MSGRRERPRQDATEQSTVSESSRKSEAGRSTHSRRGKSRAAESVDGRSAVDGGEASRSGGRGRRDSDGDSSISDESSVLSSPSNRRHHRPRFDSKASWADSTRFDMGRADSRASELSARDLRLTTSMGSRNRQRSDSRASSRLSQSSRSNRQRNASFVSNFGVNRHRKDSNALSTITEHWNLPDDEFGSPFSEFDAQEQPIRDQLQRGMDIINEHTSKLKDIEDAITAAMSEVWGYWADPIRLYLHAAERVDVQDLIKTDNELFNKVMTVFAVLCDEISELKVTVEDNFYPALIMFGQAAHGNEDEVKPGEDEVFIGRMLPFFQDISNFVDRCNAITINMLHQLASLYQSFQKLWKSTFKLVHLHPVFDALASLLEVMITIDAIVIDNPSIVTAWDKYKRMMQYVRADPTRYNISVERVKQFERLLVSLDQTIMSAQVFQTCIEQDFEAFISGELGEDEDDDEEEDGRSRRTSSDGESRIDIRTNRVFLEEFLHCISARLGQAETAMNTATETYERDNLIGTAGLYVLHRRLMPPNIPADPQLYKRLWETQLKAPAITICGKISWYMPDFLLKYAPMSSSKLQPADILQFRREYLQTLDVAFPKEVAAAKMDLSAWLVRMESFFQPTTRGMGDPSRTLSIRGNLIIKGLIIAKKVQTMMQALVNLHLTLGIPMPKSVVRPLYTCIEILKAVEFMFARKNPILAESCSLVLRQVAHSLFAYFRPLKARLEASARFDDTKLDVLAAVTVIEDILHTGESFSYTRLTILDLATQIALISPDGSASSVNGENGAVELKNAEEPIKLIWKMRLLSDFQRRIRSACDCSFFYWSRELLHPFMQDLYVQPEQSSRIQYIVSGFLDAVRLLRGAQHEEDTSVYIKAYAEFIDGVMEEEVVENLCKDVENDLRLHIHSVHLDHMDAPNPKNEDFKVLHRYLDLRPIRLYGKMLDLKQRVTHYLENTFYNLTTVALHDWKTYGEMRNLANDKYGLTLADNHLPMGSLDQGLDILQIMRNIQIFVARYNYNLNQQFFLERRSDKGSRHLNSINIHSIASSIRTHGMGIMNTTVNFTYQFLTRKFDIFSQFLFDEYIKSYLQREKRWYKKHRDDKNVDNKYPYDRAFQFNKDIRKLGISDSGKTFLDQFRMLITEIGNALGYVRMVRSAGMNYCSNAIKFVPDLNHTHFKFEAYAGEGVKELRDEESGDLIDPEIVGAKLAKESIVAARNLDSVISNLAKNFSENNDYFKVLVKVFQDVASSDGQKHLANFAYIVPALTINFVETMVQAKDLMYKNTRRRESYFTDDGFAIGIAYILAILDQGEMFDALHWFEGVTLKYQEEEAAYNQKQAERDARKKEQAARKQKETTAELIDDEEEVHTLQMTAKRIELNRREFDLLDWSLNGARIFFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJI4</accession>
    <name>A0A8K1FJI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-tyrosine-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJI4"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000130">
        <property type="entry name" value="Dual specificity protein phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46381:SF2">
        <property type="entry name" value="MAP KINASE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46381">
        <property type="entry name" value="MKPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="59"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29240" checksum="7A3A0C01F390CF7B" modified="2022-08-03" version="1">MDFLYIGGAAAAKDRDNLKQVGITHVINCAANIAPAFFPDDFQYYNIRLRDHSSQDVARYFYNVFDFIERARKRGGKVFVHCVKGISRSPTMAIAYLMWLKRVDLYQALDIVRQARPAVDPNAGFIFQLTEWEHLHAEGRIKLHNTTVFRIDIPGGSIGNGNGARAAERPLVIGPLSNISDASFSQPSEDMAKSCYVLCSPDYMCVWCGTNASEVHVEAAQYATTLLQAYESFPDKYELVTSGQETAAFWSLVEALPPLKSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJJ1</accession>
    <name>A0A8K1FJJ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010925</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJJ1"/>
    <dbReference type="OrthoDB" id="10469949at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035435585" evidence="3">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="312" mass="32800" checksum="5AA0D9B28714AACE" modified="2022-08-03" version="1">MLPKLQTLALMAAVAIACQGLATQPQASLTSMRYLADEDLRIHEEMADDDMLIEEADIDEFFDDELEADTPQVHNNRERRHRGHGQILQSAEASSGDGGVRNSDDWWNDEWPRRWDGSPEDGEWWGDDDASCSDSSSGSGPEPEEPSPTPESPTPEPQPTPETTTTSPRPTPGVTRPTPAPTGSDSTSTTSSDTASGTTKTPSSTTSTPGATSSDSTSTTSTPTQPTEPTTSSPNTDPNVSSSNKSTQSNGEGDSALSGGAIAGIVVGCVVAVGAAVGTTLLLKKFKAKQREEHMFADLGDHATSDTNYAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK46</accession>
    <name>A0A8K1FK46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK46"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF8">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="2">
        <location>
            <begin position="63"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="50678" checksum="1C50660A556B362A" modified="2022-08-03" version="1">MMPTIQRMRKLGCQPGAIRQKVLLAGGDPAWVDGPPGTKMNEDGEARRPLSTRSFPVAPALPSRPPGVLRKRVHCVLKPRRHKDPSRPPSFWESDEEKRWGSDKTNQLTNDIFSKVMKTVPATAVKCATAKPLICLLDLKKSFNMAITLARLAISPVELKNEILALNPTVLSCEQVQTLIDMWPDQDEQSVIDNFDGDISTVGHAEKFLLEVRSIPRFCEKLRCLLFKQNFPSRVHELRESIQLVIRGVHQLCTSSALQSVFHYVFERIVFLNYGPSDTAEVMLGIRGFSLDSLPKLSHTKAFDTRQSFLQFIVHCLRHDHPALTTFGNEVMLLQRCSRVPIASLVAEKRVLESGLQLLHHEAKTMVSVDGKTEITAMCMAQFATEVESELKVVDELMEQLDESKQSFLEHFEEQDSSDELDVLLGYIADFTLAFELELERITLETRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK63</accession>
    <name>A0A8K1FK63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitinase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK63"/>
    <dbReference type="OrthoDB" id="10254444at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070492">
        <property type="term" value="F:oligosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066:SF2">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424073" description="Chitinase domain-containing protein 1" evidence="3">
        <location>
            <begin position="20"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="4">
        <location>
            <begin position="103"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="44001" checksum="515B64694E30E4DB" modified="2022-08-03" version="1">MLWTLVVCVLVSQSTRVAASRYDAGEDEDDEDADDTDGFDFLSTKLESIPKGVETAGSGACDVPGLVESVVKRGLVTPRPTIQSILQEHSRAASDVETRAFQGETLGYVTPWNNRGYDWAKQFRRKFTYIAPVWLQIREDSKTKTPIITGSHDIDDQWVADVRGGDGKGPKLVPRVVYERNRLNSNDVPVIIDLLVKLARERALDGFVFEIPIIPGTMDMLLRVGEALQDADKLLLLVLTRSSNEGALPVTHEMLIDLLPVVHRFTMNAYDYHLPGPNAPLDWIESTLEHFTDNEKPKILMGIPFYGYDGHDAIVGSSFAQTLKTHAGSRLQWDGSAHECLYRYTGDDEQRHVVYYPCLQFLADRLQLFQDHGVGVAVWELGQGLEYFYDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLA1</accession>
    <name>A0A8K1FLA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_002573</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLA1"/>
    <dbReference type="OrthoDB" id="10249672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07959">
        <property type="entry name" value="Anticodon_Ia_Leu_AEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000001">
        <property type="entry name" value="Leucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.20">
        <property type="entry name" value="Class I aminoacyl-tRNA synthetases (RS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.720">
        <property type="entry name" value="leucyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="37"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="200"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="807"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="12">
        <location>
            <begin position="958"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW63632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1086" mass="123186" checksum="6438C2A25F561EBA" modified="2022-08-03" version="1">MVVDKVAVQLQDVKLEEKAAPKNTARRDHLIEIEHRIVQEWDAAKVFEVEPDLSKPKYMVTFPYPYMNGFLHVGHLFTITKVEFAARYHRLKGENVLFPFGLHCTGMPIQAAANKLKHELEVFGFPPDFSADEAAAPVKKEVKVEGSENKAKGKKSKVAAKTGGIVRQYNILKMSGIPEDEIPAFTDPLHWLRYFPPNAIQDLKRFGANVDWRRSFITTDVNPFYDSFIVWQLNKLKENGRISRGKRPTVYSTLDQQPCTDHDRASGEGANPQEYTIIKLRVQEPFPEHLKPLEGKKVYLAPATLRPETMYGQTNCFVLPDGEYGAYVLDDSDEVFIMSRRAAKNLAHQDRSREWGQEECLLELKGWDLLGLPLSAPNAKYETVYTLPLLTISMGKGTGVVTSVPSDAPDDYAALRDLKQKAAFREKYNIADHMVLPYDVVPIIDIPGFGDLSAVKVCDDLKIASQNDKDKLGKAKEMVYLKGYYEGVMLVGSQKGLKVCDAKPLVRQELIDSGDAFAYWEPESTVISRSGDECVVAHLDQWYTNYGVDDWKNRVLEHVSDPAKFDAFNPIALGEYKATLEWMKDWAPCRQAGLGTKLPWDPQFVVESLSDSTIYMAYYTIAHHLQGNLDGSVLGPHGITADQMTKQVWDYIFTKGPAPTDSTIPITILEKMRAEFEYWYPLDVRASGKDLIRNHLTMSLYNHAEIWRDDPSKWPRGFFTNGHVQIDGKKMSKSVGNFLTVRDCAEEFGADATRFACADAGDGMDDANFALETCKMAILRLTTEEDWIKKTLEDSDKLRTGELTFNDRVFMHQMSHLINETAKFNDRMQWREGLHTGFFEFQIARDGYRDICARSEVAMHRDVITRFMEAQTIMLSPVTPHFCEHIWKLLGKDGFVATALWPQTEEVDFSLLRAGDFLGKTARHFREALTKGPQKKKGKSAAPVETKKPTHAHVYLSNEFPEWQQKVLTFLASVFDAKNKTFPDDFMKLLKEHVAKDESLKKITKNVMQFAAFVKDEAIVRGQEALDLSMPYDQKAVLESNKLYLLRSLDLEDITFYYVGDEIPGADEKKLELAAPGKPAIHLYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLF1</accession>
    <name>A0A8K1FLF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLF1"/>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15568">
        <property type="entry name" value="PHD5_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46695:SF5">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46695">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="310"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="65303" checksum="F17A6F286480F6E2" modified="2022-08-03" version="1">MGFRGVLLKLSEGEADELFRVVCPDASLQIPTVTTPAQNQGTGIAEQKMVVVDQVTALPQQVTRLSSVLPQPRTRSAFWVVTQPAATAGEEEEEEEAPMAGSVRVFARGAPPLTRVCYCFYFQSEIEYELFARVCVAASRLQQYDMLERSVLMELEIKKNVEIEREEIKRAKEARSRASLAAVASARPQRNPPVASRRQGPSEPERSRPRPTAVTTDEMAARLESGRSPRTASQSPVVASEPVSSQTPHCILCGTEANAGRAGTLIKHPFVLKDAKGEAVLVCKICMQGVLKRRVQNDAGLGTSTANSVCGLCSEAMATTKTPPRKCAHPQCQRSYCSPCLRKLVGKAQTKKVWRMKNWYCPNCTDLEGKPTVNENPTPLPQQPVVTPREADTPSKKKRKRRNEIVDDDESTASSSPSRLATAGATNQVMTIVDYAATYYEFLSERESQRPPPEESEDVCFCCKDGGDVLECDYNEGNRKCPKVYHQDCLGFTVPDNVNWICPRHRCFACGFQAPYSCRFCVTSFCEEHFPKDIKKLGKASGDLPDVQYVLCGGCDKMSLRAVEDDKLSSKVYDRVVHGISHRARSSKASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLN0</accession>
    <name>A0A8K1FLN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLN0"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="7">
        <location>
            <begin position="31"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="31059" checksum="AF81020F088F5EFF" modified="2022-08-03" version="1">MTDTTRTRQPAVFVPHGGGPMPILGDPGHAEMVQWLKSFRKTFIKTKPDAIVLVTAHWEEKVTTITSAAQPKLLYDYYGFPPKAYDIKYPAPGHPELADRIKGLLGEQRILAKLDDARGNDHGVFIPMKLMFPNADIPVVQMSIYDSLNPEQHIKLGEALSSLRDDNILIVGSGLSFHSFKYFFGDKAEANRVSVPFHEYLVDALVNTTNPSERRKKLSQWSKAPFAREVHPREEHLMPLLVVAGAGLREPCQEIFSGLVMDIRTSGFLFGDETSTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLN3</accession>
    <name>A0A8K1FLN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 4-like WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005898</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLN3"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF39">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="4">
        <location>
            <begin position="389"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="456"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="541"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="583"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="619" mass="67532" checksum="3CACCB57485E2490" modified="2022-08-03" version="1">MDPSSRSGEGSVAIELEHTIGFSAIPNAIFYHPSGHDYLYAAGGSVCLTSFQDAHSQAFLRGHDAAISCMALSSSGRLIATGERGRRADVLVWDYSTKKTIYRLTEHDFGIAALAFSDDERLLCTIGIPEDGRLYIWDLFTGNICATHQKLSAIVTSVAFGGMARDIKHRDTNCYQFATCGNRLLQLWVLNPMNGELVPSKIEQTVVRDFTCIQFSPDRETLVAGSTSGDFAVVNVKTKRLLKSIPACSCGINAIQFFNAGVLVGGGDGSVLYFNHDFVDTSVATLDAPIAGLTLNAAQNEAVVGTQAGSIYRVQMASNQRYLPWSLLSSNHSSAVIQVAYAPDVFDRFATISKDCTIRIWDASDYAAVTKSFVPDAGLPTSLQFSLDVLLSGWTDGCIRCHSSDTGEAVWSIDNAHTGGVTALVLSHNQRFIVSAGVNGEVRVWDIRKRDMVSHLKEHSMAVTCLALFQDDLHVISCSRDRSILCWDLRNERRITSHIQRMGGINTVALSANQKLVLSAGQEKRISYWDLRIDAPVIMIQKAHEEEATCIAVAHSLNLFATGGNDRVVKIWNFNTGELIQDGIGHSGNVRGLAFSPDDRQLVSVGDDGCVFVWNVYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLQ4</accession>
    <name>A0A8K1FLQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLQ4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434367" evidence="2">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="105" mass="9317" checksum="8B0BE2DD292E50A2" modified="2022-08-03" version="1">MKFLALLAAVAVATVSAQSAAGSAAADVKVPAAGSTTGSTAGAGAEVKAPVAAGSTAGSDAAGSTTGSTTDSSAGAVPTPAPSSAHTIAVSSAAAAAAVAATYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMS0</accession>
    <name>A0A8K1FMS0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006019</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMS0"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="113"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="63290" checksum="384E84820CF8F44B" modified="2022-08-03" version="1">MMEGFGSPPSTPAEASLSRSGLDPSSLDPESILSPDEVQLLHRRFAAFNPNANKTRSLAAAHAIRLFRDDFSTLSEWEIQELFTRCDLNNDGQLAQHEYVHARAYHRVLVEAAREDDVVRSFTILDTDSDGVIHAKEVLHLVEQARQPSARLLKQAILQSAVATKQSSHPYHRASTNHEEDDITCDHFVTTIRDVNRGIEREIAAKTVRMLSLEDKLHHHQETLQGVASGFDRAALVAKIESVQIEIDVLKKEIARAKREFVVTDSNSALTKICETLVATYENEQHVYECLTNFITYCGLRDPVLFRQRLEAAGRQVNVLDSILMAPTHHVQTTTEYTLLTDLTLRYHNCRDVHTPSAHRIHERQTSGFALDASRHARLLTNSTLRRHFAYYTMAGSITNLATMTRSNFAKFVKDCTLHTLVSPPLTDPDIDSIYATATRGTNPQEQHHRRERAHMTFVQWLVACELLLQRLEPNVPLNPDTLEALIKVHVIARAKVITTQNLAPDVSQIHVLKLLREFLWLFKQIFAHFAGHSLIEVDTSIALSMSRFLRFARAFGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNC4</accession>
    <name>A0A8K1FNC4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001397</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNC4"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="41132" checksum="D3865B9C9157995D" modified="2022-08-03" version="1">MQRGETALHCASVYGHAENAKALVAHGADGTTKDQSGKSALHTAVLFKKLDVIKALLTHGMDPNIYDTVSNPQDHQAAVVACILDCGCDVNVRNASGKTPLATCIQWAPGTYIFLRVLVTAFALMSSGAVLEESEENFPPVHVMYQARAGIVPVYVNHWAKQQQNGASALTPVLRGMTLGGLESLEAEFYQNQELERLLQDGVDVDAVKPGGRTELHELVIDDAGLDAVKVLLAHGANIHAIDNYGATPLHYACEQLGSVEMVELLLTHGADVNAINWGGRTPLHVADMSKTDIVDVLLAHGADVNSRSGTGDTALHRATNWCADGVVKPLLMHGADATAKKWIRLSGHFCSRGVGKKRGYPSISRARDRCGAVLLGWHDSASVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNM6</accession>
    <name>A0A8K1FNM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNM6"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="30308" checksum="EECF7231E5A556B9" modified="2022-08-03" version="1">MAVDDDLLAQLVQFLSSTESRNKVYRLIQYSAKLSKWTLMTMWRLRPEDLRELAHVPEHKPPNAVNGHTHKASTAEKESSTKTAVRRVAAMLSRVEGLFADGRKVYRLLQFLEMLDMLRHVHEPEAAVRVLRRLRIVCFFFFNLLENYMMILLRIKLLPHRDPRVVFLKRACNGFWCLSIVLAFPLDHLMHRNSHLSTIKKLLDLPVAYLAFADHRVNDGLFSLLGVASANIGVYLRWIEVVRKMQSKQSSIRAPPIMPALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNU2</accession>
    <name>A0A8K1FNU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNU2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472229" description="Translation initiation factor IF-2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="42183" checksum="F6CA4C9F9D3FD1D7" modified="2022-08-03" version="1">MLSLRKLCALAVCATALVSSEFIAVTQAEETGLTTTSAVRRLRVEASTDGSAPGSRPPQGGQGAGGSRPPQGGQEAGGSRPPHARHGKGGFSGEFGAGSGAGRPSGSRPPQAGQGSRPPHAGQGSRPPQGGQGGQGGQGGSRPPQAGSGAGRPSGSQPPQAEGDASNYAFPTQGSGAGAAGRPAGSFKPSGSRPPQAGQGSRPPHAGQGSRPPHAGQGGQGSRPPQAGSGAGRPSGSQPPQAEGDASNYAFPTQGSGAGAEGSFKPSGSRPPQAGQGGQGGQGGSRPPHAGQGGQGGQGGSRPPHAGQGGQGGQGGSRPPQAGQGGQGGSRPPHAGQGGQGGSRPPHAGQGGQGGSRPPNAGQGGQGGQGGQGGSRPPQAGSGSGGPPLPRPDGEGKPSNVPSGVPSAVPTDAPTEQPASYPTDDDESDAPDTVESDAEDDESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPJ0</accession>
    <name>A0A8K1FPJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPJ0"/>
    <dbReference type="OrthoDB" id="168039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="377"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="231"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="487"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="693"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="487"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="767" mass="81815" checksum="9D8D06506DFA3623" modified="2022-08-03" version="1">MSDLTRAQHPPQHHHPQHLHHVQQPQPQQPHYAPPSTQQLGGVTNGASTHKRFGGGVPVPPVVLSPATTGHDSSQSYVYGQINAAYAHQPGLMKDRMMDYQFQPQQYGSGGGGGGNGTPNSNPASTPNGYNHHQQSTPVTTPSTASSTTGASYSSQGQYVYGSAPHQHHVSLHTPVTATHHSLHHAQEAMPFGVHEAPQPPLSMPQLSEIHLPQDKDTDRKYRPLNDMYLNSQGVYSTGSGGSSSHSERNSNSMSESAYLSMRYQQQQQQQQQQQQQQQQQQQQQQNMSAYRAGPQLMHQQGYGAPQQSHGSFYGNQGRNDLMPPAMAAAQAAAQAQGLRSSQLSMGGRLRDPSGMENSMRIQQQHGVLNSPQDVLCSFCYAGQCDRIADGCGHQFHQTCLQAWGDKSLNCPLCVPSAHPIKIMQQQTSYQMSTIGQHQQMYQQQQSQGLSPLESMRPRLRTQPRPPPIDTTRGIDAAAVAKINMMTNNGQAGTPLGQTTPSSDMGRPMSTMSSSSDSLQGEDAPSSGGRNSKSKGKKPLKECSIPGCGRTVRSRGLCKGHGGGRRCGFPGCGLSDQGGGFCISHGGGKRCQHDGCENSAQSRGLCKLHGGGSRCTVPNCTKSSQGRGLCRAHGGGRRCMIDGCNKTDRRAGYCVTHGADKKCVIPECSKTGRIDGMCSKHYFERNQSLLAASGTPMSSKDVKGKKKPVGKASRPKMTPGTSPTTPTLLNSLNAVSLLSAASTPSNGAGPSAAMLNGLAAHSVGVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPY5</accession>
    <name>A0A8K1FPY5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPY5"/>
    <dbReference type="OrthoDB" id="147348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="95" mass="10905" checksum="206CFEA960545F6B" modified="2022-08-03" version="1">MATKAKETKEVDYVSKQANLTSQIESERLAAKKWWEEYGTCYLDNAKLEDFTYENRIAALKGKLGSDKYQNATLHTTSADYGCRPPFKECTRKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQT9</accession>
    <name>A0A8K1FQT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQT9"/>
    <dbReference type="OrthoDB" id="6121258at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="523" mass="57829" checksum="B8AE73F8B8D02F8E" modified="2022-08-03" version="1">MEVFWVLPSGPLSTDEMAGWVSVEDENEIPLGYCLSENLAPIPCQSSFFSFGVLSNNGTNSSGYANGETKDGHVSRVTNFSTAVLHRYSMKGAEMLISNKNRDAYWSVNSTTGRLTVVKQDKASLFRMYKLVGGQGPVLLKTGSFYLALGDSGMYGSQVITSEHMLFPAQPTYGDPVGIVDALDAEIMGSRFQSLSNGGELYPVWMAYDLALVIPLRDLPEAPDFVDFTMENATAFDLIPMFTKFFHLVANRMVKAYNHYPSLAPSYPGDLAFINITRLMDGYPTSFRLPSDNVTWLVDHGWLANVEQAKQVTFVKAFRLFLPPRFAHYDKEPASVELVVKSHSLSDLGPARNGKKYEIPRVQYKTEYTYGAWHETPQLYERVVYHECNANLPPYCVRSRGIAQTNTDILPSLFSEWEVTAQLNRNASSIRIGYRHAVTPLLLHAQVELEHVVDQPGPVASLIDTSALPASRRELADDQVACCAEKDEYHARLGSSAVCLPCPAGSISQLGGLYCVVDPRVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRS2</accession>
    <name>A0A8K1FRS2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRS2"/>
    <dbReference type="OrthoDB" id="124765at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="417" mass="47301" checksum="B064AA2EC0F38FA0" modified="2022-08-03" version="1">MTDPDDMLADVLAFLDEYATSEAVNPQDDALNTCPDGGEAVKTKPKPRRQETLARRLCRNRGRERQRLELLELRHETHVLSARLMQMQKKNASRRRAAACGDAQTHQCALEMTSVWHELASRQKQRRQAAEEERARLRARVVEQQHVIKSLQRILARYSADAVHSPTASSRLYAPAWRAMCADGDPLRMMQIFADLVVDVKQAHERTALWLPTHWSSSLTNGRYRDSRVTQLSPTQLMIETVNLRLMPFPYRKAGLAYWDGGVNHHCAKFDYFREGSEVEGRETVFCGQAFHDGSGDDGVAMFRLCTHMSIQRFEENDRLIVVNAARSDSIRINGHELRDVHVKEQYWNVFQSPETMVKDACLMTSFGRVIMEVAGGLNQSPLAVLGATNFFGDRIHLHLNAAVSSVEDTLLDAMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FST6</accession>
    <name>A0A8K1FST6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FST6"/>
    <dbReference type="OrthoDB" id="2015831at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="389"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="775" mass="87372" checksum="71B3B74ABB8D0A29" modified="2022-08-03" version="1">MATLVAASSAILTSGSSIELQLIATEDGVLPSTDDAVQPVKRDTLTRLRQSLFRRSGSSISEDEYVDPAEELVFLEVRPWVFGAVWWVMIVIHICCAMILSLQSRLYIYLQSPYMSYYVNLLEPGIASMYPVVAGVFGVIAVMHWSVVLRLIYYSLSQRKYAFFPASHDAIPVHRIPADKVAVPLTRWQRFRHGLHAFKLAVFGRRGVLGPESRFFYANFYIREAIELTSQIYQAYRASLLVSRTWVSHLSVAVIAVNCFSTPLIQFVYKRRPEVRRIALLAIDAHLDFIMAMVIPIGMFIPYYWLFDTTTMSFPTEKVYDETWFIQAILENQELYMISTMDMLLKCVPHVSITSCLKKVRALIRKDTSVVSISGRVVTRSVVAPSERKLKAQEKLARINAKKAQKKQEAEQAVRVSSAQVLTRKTRAKLSWGIHKYAGKLIRLVFLSIAFIIVALHLLAFYTSYRSDKSGCLQPMRPWFATKFACSVYRLDCRYLNTTGRATDITAALQKLYAPAVVGIGFVHCSALEIPDTINEYNHLMRLDMYNSTLIRWGASAALTRSSHPVMAAVSFARVQFSNATLPDGMLSDEFPDALMSIELSTTNLASLPSDLHKKWPRMTKLYVEHSQLTAYPTTLMDLDVEKLSLSGNQITALPSTWGSRDIDRFELALAQNPLMALPDNVHEDTSIAYLFMHETKLSSFTSWITTNVGHVYAEQTPFCEAQTPVQRLAEHHADAQIACAMSERVAAMVDVGGGLYPLALIDRIQLQEDAREKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C295</accession>
    <name>A0A8K1C295_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S acidic ribosomal protein P1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C295"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="11521" checksum="747F93D336470EA2" modified="2022-08-03" version="1">MALADLTPIQKEELATSLAVLAVYDASAEISAENLSAALKASGNSVSAYLPQLFADLIGRGLTIDKFLAGPSAGAAPAGGAVAASSGAAPVEEAKEEEEEADIGGGMDMFGGGGSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H9</accession>
    <name>A0A8K1C2H9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="609"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="652"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="756"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1231"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1263"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1307"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1339"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1372"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1470"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="178"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="870"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1500" mass="167275" checksum="38F2B8B880922D45" modified="2022-08-03" version="1">MSRRPNDEVRPVETSDLDAALAGVMGLPELILRASIIEDDDGDEQDTTEDPPIAGSAQARLRPRQGSSLNVVDETRDVVPEIDHTVRPERPERPDRAEARMSMKMKSTMLERYSSLDATTLESMLSGGLDRFFGKFKNAWKKHNLSFPTPEITFENLSYEVRMSTEPSSSAGSIGGFLRAAVKPWRKLKKEKKTILHPMTGCIRPGTMTLVLANPGAGKSTFLKALAGKLSTRRRRRFIKGSITYSGLAAEEIQIDKLVGLVDQADNHLPTLTVRETLEFADRCLNGFPEDKPEKLREIARLRTDLCMHILGLTKCADTVVGDALLRGVSGGERKRVTIGEMIVGHQSVFLCDEISTGLDSAATFDITQSLKSFTRTLGGSVVIALLQPPPEVVELFDDVLILAEGRLVYHGPTIEMLSYFESLGFGCPERVDPAEFAVDVVSGRGAQYLMSDRVAAMPAKPPRLAEHFEDAFRRSERYLTTLRTLESKKRHMAKVQNETALQSVQHLISKHEGGNRPTYGMGFFESTAYLFQRQKKIWMRDRALVLGKMIEAVVVGLLLGIIYYNVSSMNYLRMIFFSAAVFQRQAWQQLPIAFQVRNVFYKQRSRMFFRTLSYTLAESIVQIPLNVMVSFILSVIFYFMSGLSRSASTFFVFYAIVVTFQHAVTAYYTLLAAFSPTITVAQSIASLSVSFFLLFSGNIILPLLIPTYWRWMYWFNPLAWALRALLLNEFHDSRYSDAERIAALARFQITKGPEFIWIGILVLAAYYVLFTLLNTAGLHWLRFEVQATASVSTSSMEESYPDQTTASASPQSDVQPSVIAGGGAVVTPTPESPDHLIVPMAAKPTLGPEASRMESGDTPAAVTCIPAYLVVRNLEYFVPHPAQKGEELQLLHGITAHFTPGKMTALMGSSGAGKTTLMDVLAGRKTGGRIEGDILVNGEPKDPTTFSRIAGYCEQMDIHSGGATIQEALEFSARLRLPASTTPAERRAIVQNTMDLLELNGLALELVRNCSIEQKKRITIGVEVVANPSILFLDEPTSGLDARAASFVMKGVRSIARTGRTVLCTIHQPSVQIFELFDSLLLLQKGGYTAFFGDLGQGSELLLQYFASLPGTPSMPALYNPATYMLEVIGAGIGRQGAGQARDYSLEYKKSPLCESNRVVSEAIATGNVPPEFMWLNDPTSTKPTEPAQSALTKFSSLELMPIASSFYVQFRSCAAKMRLTYWRNPQYNLVRIVTFPLYAVIFGTTFYQMEETTMAKVNSHVGLMYNTLDFIGVINLMTVLDTVVNERAVFYRERMSNYYGPLSYALSLWLAEIPYLLFVSIVFMAIEYFLIGWESDASGFFLFWFVFFLHISISTSIGQFMSVLMPNIKVANVAVGAISVLFNLFSGFLMPHQDMRKFYSWIRWLTVTNYSLPSLVSIEMGRCTSEDLVSKIHGCRIVAIPATGETPATAMRLTAFIYKYFHFDYADLWWNIVVLISIWVILQIAIYLTLRFVSHLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2X5</accession>
    <name>A0A8K1C2X5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2X5"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF46">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37909" checksum="9FDFA79D3567AFB5" modified="2022-08-03" version="1">MKRNGAVEDMAERRKARRVESKGEASEGLYGDVEEMGVHAQWIEGLATCGYVVVPRFLTDEELKMLREESDLLVETTHEDPKRAVECIIEQGCVVDMMADCPMEDASPARVEADAYLTARRKELGRRCQRHSPPKAIPEGSSDVLKKLLFERLPYLARLLWRRPATPPARQDLFFFNEHYVVKPPQTEAEFRWHRDDDEQLAMCVHRDSIAPYLSAWCALDDISPTNGPLRFVPLQNSSSSHALQPQSICSLEEADLEWLDSHATEPVLVHSCDVIVFRSDIWHCSSQNASERIRRAFYAQYSQEPITARPCESNPLSFAIPCGSSTSFPTIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C333</accession>
    <name>A0A8K1C333_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C333"/>
    <dbReference type="OrthoDB" id="343609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476864" description="Kazal-like domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="19"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="162"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="229"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="303"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="37712" checksum="FEBEA9501B74A2AC" modified="2022-08-03" version="1">MQVVSILRALAVFAVLDSVSALRGCNMRCTNEMKPVCGSNGFTYDNECHLKLAKCADPDSTLSVVSSGECPTKDQVTATPKGDGCEVLCMDSFNPVCGSDGVTYSNECQLKQANCGKNLKSAITIASTGECATDADASDDNDAEMTIGPAPEPEPVTSDAEVGSDSDCEVSCLSSYQPVCGSDGVTYSNSCELKRANCKSNSRSVGITQVATGECAEAAGSAAAGSETPEPAAGCSKICPSSYSPVCGTNGVTYANKCKFEVAKCTIRIATLAIKSEGECTAASSDDGDDDDDVSDDSGSAEEPVSGGCSRNCSREFKPVCGSDGVTYTNECHFEVARCTKRIAMMSYKDGSCDERRRALRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4P6</accession>
    <name>A0A8K1C4P6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Autophagy-related protein 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006383</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4P6"/>
    <dbReference type="OrthoDB" id="447953at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019460">
        <property type="entry name" value="Atg11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10377">
        <property type="entry name" value="ATG11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="7">
        <location>
            <begin position="137"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy-related protein 11 C-terminal" evidence="8">
        <location>
            <begin position="771"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="503"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="625"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="757"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="893" mass="101695" checksum="E100E035EB814E14" modified="2022-08-03" version="1">MDCVLRVGNSVNGVVYTVRLASNDLAVDELRDELVRLSDIPSNDQILLSGPPYARLDPRRAISSYGLPASDRQIYLYDRRMLSQEHPVPPRLALEPVEIELPTVPVMSSENQQMLNESSYPLLKALLEYESHFQLQVNQSEAIERASAANVAACERSVKELEVQSNAIRAAIANVEVFRESMSKHFLPFWNEYEEVASQHEKLLAQFETHLAALSTVTLHPALATGDRKTLYDCVPVEREREWAYQCEHSHLHLRTQVARLKQVHEEVSNDVSTLVRSQDDILVSYQGAVRDLSQMQQYVTAQRDITGKLEETLGVVVRKIAEASSEMPSGSSMFASTLFLDMCRGIDELYHSQHDLLPSAQKSAEEIKATMSKMSSIKLSFFSHVHSHLRRISVAQSKIRDFENSLAMLKEALHAQKKHFNELEHLAKLPESYTACLREIARRVRYGRQFSDRIQSMAEELAQMRDEEVNHRERFLRVYGQHLPRDFVPGLAEKPSHCEFRMRPFDQNLPPIEDESLDDGNATSEEETKESDADTAGRSVCDPHTNNLETELLQKRCEELEARVAELTLELQQKKDSSYYESIVQSELSEVSAREGDSSCEFPLVLALAANAGGMTSSSEVDQSNLLERELQSLKSVKEEAESRNREKDEVIVKLESENQQFLINAAAFEEYPFPRVRGLLGPLEIQERTRREQQLQEMQTKLQASLQNLQGSIDTQRASLLRVLKVLGFWPPRDREVTDTDEYITSHMERVETRIRELTSSADTEKVLRQELERQHEEINLLESQHFDLADSFKISFRSFHVNDLALFLPTSAPGSDAQRVYLAFHHGCPHRFLSEESISSFMIGGRKYPDYVVGRIVLIDEQLATESNNPYGLHLGTTFYILTVASLQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4S8</accession>
    <name>A0A8K1C4S8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4S8"/>
    <dbReference type="OrthoDB" id="551053at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038911">
        <property type="entry name" value="SCLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35970">
        <property type="entry name" value="SODIUM CHANNEL AND CLATHRIN LINKER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35970:SF1">
        <property type="entry name" value="SODIUM CHANNEL AND CLATHRIN LINKER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="448"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="537" mass="61949" checksum="25A5C1F15B7A017B" modified="2022-08-03" version="1">MSGRGVRADGDDDAHGGESGPQAERSRRLQTQALRMCPPVMYEPKTQTRSVTDTSTRPPPLVVGGPCAATASCHLQIAQLGDEKEFLTKYVERLLNQLRQVLQRHGELEKLKALSDPVGTSRAEAAGEAGETLERTPPWMTAEDYVNPLFQSYDLKIYELEHAVTENKKTMERIVSRAESLAKENSTLRQELEATAEKLVLRMQHEPKDPHMLHDELLMPHDTSEYLSEINERIDVLMSENNTLMEQVSLQDDELSGLKKEIADRDDQLQVMSQNFNQATLAIQELRDSCESIRDEKLQCEQQLQQYAVKLAQFENQKESIVAQMESLRTEKKNIETQVQEYERLLENAKKNAEHKDETMSHRYQNVCSRLRELNSVIEFKQKRIDELEELNRGLNSELESVRQDCEGMLQVMNSMEKQLSQYCSREDAVAELEMECKAKIEDMMIEKEQIVARESQARREIARLLERIRTQGDEQLRGEEQRAHDVSRRYEQDLGSREEQIRDLRTELAEVRANLVRVFVFDMYSLSPFEPNSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y2</accession>
    <name>A0A8K1C4Y2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006503</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y2"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048674">
        <property type="entry name" value="COQ9_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21392">
        <property type="entry name" value="COQ9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="Ubiquinone biosynthesis protein COQ9 HTH" evidence="11">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="COQ9 C-terminal" evidence="10">
        <location>
            <begin position="184"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="363" mass="39648" checksum="D7EC39AB108A5286" modified="2022-08-03" version="1">MRSTRALKQLQRLATRGHVQTTRVTRSVRLAAVPLQQRAQEAMAMQSTRMFTTSAINEEESKTQSATEDPFVNPEKRILENALQHVGEFGWSVEALAAGAKDMGYPSVAHGMLPRGAIELVDYFMDKCHEQMREQLMANREALQAMSVTDRLKFGVRTRLQLLAPVISTWPQAMALGALPQHAPSTMQKLATLSDEIWYFAGDKSTDASWYTKRALLTGIYASTELFMLTDESLNFEETWRFLDRRVEESISLGELPRSLNDVAGMMTIGVQSLLSAAVSLAGPLSSQIVKNSPLANVPNPISAINDVVPPSVAAGLAAGLPSNPLASQPTPYNPVGGANFEPKDLHDIDAELEKLGGADSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5A9</accession>
    <name>A0A8K1C5A9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5A9"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000383">
        <property type="entry name" value="Dynamin-like gtpase dnm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="22"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="611"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="78506" checksum="AF8C2ECA98CF3867" modified="2022-08-03" version="1">MDQLIPIINKLQDVFSAIGQSPINLPQIVVIGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLVLQLYNISNTDLAKESDVEEWGEFLHLPGQKISDFSELRKEIERETERMTGKNKGISNKSINLKIFSPHVLNLTLVDLPGVTKVPVGDQPVNIEEQIRDMCMEFIANPNSIILAVTSANTDLANSDALKMAREIDPEGVRTIGVLTKLDLMDDGTDALDMLQGRIIPLKRGFVGVVNRSQADINNSVSIRDALSKETSYFKNHPSYRAMASRMGTQYLSKTLNTILMHHIRDCLPDIKSKISSMVNDLDLELGEMGNPTEKMSKTEMGGCLLNLISHFSANFTNSLDGRNHSLNGVEMNELYGGARISYIFNEIFTKALQDVNPFDGLSDEDIRTTIRNANGPRQSLFVPEVSFELLAKRQIARLEQPGLQCVDLVFDELQRVTSQCENMELSRFTELRDRVIEVVNSMLRSSLSPTQTMIQNLIQIELAYINTNHPDFIGGSRAVAQLMEKLQRESLSAQGPGVPGGVDPNNQRRLSTGAPNAKPTVVTEDKQESGLMSYIFPGSKKSKPATPTTDGYGKPAVVKLPQVPVSMRQSEEPSDRERIETEIIKSLLASYFDIVRKNFLDLVPKAIMNFMVINAKENVQNVLVSALYREDQLNELLRETGDVAARRANCHEMRMLLQRALEIVNEVRDFNTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5B2</accession>
    <name>A0A8K1C5B2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5B2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="20790" checksum="A0AA9B3FEB5A002F" modified="2022-08-03" version="1">MENAWHPVVYSSTNVPVYYEHIPIQPFHHASSPLYMPYHRYARSATCMYGTGKCKHPQAIKRNGQRHRLCEFHRQRANLNQLRLDRRRRRERKTPEDRHPASGSDDTSPRSIEDFHVYFGNPLPVYWSDVSKSDQEDMMTVHPDGLEEDCEVLFDAIAAIATIDVDALNLTVQSHFVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Q8</accession>
    <name>A0A8K1C5Q8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003006</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Q8"/>
    <dbReference type="OrthoDB" id="70707at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="110"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="274"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="387"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="445"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="499"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="683" mass="75628" checksum="6BFA145284DA8C1D" modified="2022-08-03" version="1">MGLLRRKKLDIRVPTGKDAVNFRKLLFLAIKDSQDLLSNSDWERLDLRCLTLMKTRMLRASCIARGLPRKGGKRKLVERLMASLTEQKNAEFLRRQQEEEEYQWHLDLLGGVWTFGSGFSGQLGHGDLESSGKPRLIKKLRGRGIAQVYAGFDSDVAFAVGRNGDVYVWGKRTGPTGLSPDASLSLLLRRSYRGSGEDLDSSDEEEDAGDTKPLQAGLGRVEENGAEESDGDEEEEDGGDEDFVHPVKLFSLCGEGINHIAVGRVHCCAKTKDGDVYTWGHNDHCQLGYEPTHNLTEKQSKKARVRYGLDTNEPCLWERTISEACVIQAVAVGTNHTFVVTDRSEVMAFGQTFVTDTQSSLSRSLAKLQVVQISCGAMHAGLVTTNGQAYTWGSGDGGRLGHGDTTSYVNPKLVEALQDDVIFELSCACWHTVAIVLIPPLLKGGLVYTWGSGRLGQLAQGGKQISTTPGLVTDLLVTHVLIKKVCAGMFHNVALSVDDEVFTWGSNTNGCLGRPDELGNLEEEFCAVPGKVEVACGREFTLIATKPYIGPTREELERRAEEQAEKVDRITRESKNVKTYKREQLDRIRRDKINVMVQFLNKSFPKCSICTIGTVCPGFQRDDINPAMCKHCLHERRKHDYSHSPSVNLAHLAEVTRKLAIEIDCSSVRDIELEEELADELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C649</accession>
    <name>A0A8K1C649_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003214</name>
        <name evidence="3" type="ORF">Poli38472_003216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C649"/>
    <dbReference type="OrthoDB" id="160470at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="633" mass="67442" checksum="859D5F50B3175DFC" modified="2022-08-03" version="1">MSDQQKPVDTNQVVLDKKMPSGGTAKAAAATAAWKMSKFSCIFTVLAVLFVVGNVIALYVLHFVNRPSITARFSFSNFLATTGTVAQVGDVVSLSTSSKVRNGAGTTAYLDRFALKDSPNDGSSNALFYEYLNFAPMGTTKSWYTTNLVSYRRILSHDATNGKKGDSILTTATYSPDTKSFTIDTSYDLAKTDNRIPSQAIRGIATLSDTQAVVLSIDDGASPYKTNVMPVSIKDGKVSIVSSNVKLVASGSVTNLIARLSATTFAIAYYEPWVDGAQYGQRIEVGTVKDDGTLTLTGASVLFGPMNDDASAKKFTVTFGTPQLIKGEKTASTMVIPYYGVSTKDTTLNTGLCVTMGSYVSTGTISAFTTGICNTKYQPTSFPESVMVSDNLLAIVFYDSKNNNALTIALVYVTATSANFRGEYVLTEALGSFVYGSAYGFSPKPSLALLSGNRLAVSFLNAAMDGKQCVKVFKISTSANNIKSVTPVMPVAAQDFTLVVDPTDDLQNNAITQELIAVSDDGVAMGYVGKRPTPQARFTVMEAFGAPVGIIRSYDGKNEVSVAISGKTTEVSTPKSEELVEGQFYYATTAGYVVPSLSDNLGEYFKYDDMLVATDGKIGVAIDDDKLFVSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6F6</accession>
    <name>A0A8K1C6F6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6F6"/>
    <dbReference type="OrthoDB" id="67398at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="40617" checksum="32F0D64FFB0FB79A" modified="2022-08-03" version="1">MAPGKGKSDDVFGTLVTTAAKILAPNSLQFDDNEFERSPAEAKQAATEAAKLVQPGDLIFITTKGFIYSMSRFLTNNEYDHMVIVLNDRQVLHVGPPSVRLIQLERLLLPQRQPVVLRPDMTEEERQRFIRCAYQLDGSKYDVVRLYQLMLRISLKKNLRSTPLGRLPLDVRNHAWVCTDAAMVLLAGCSDRFRQTLTRAKEELELDIITHGSASFNDFTRLRQLEPTLMPRINLPVLTYTSNPHKRPLRAYVGEFLELITRIQSGKVRWHLFEQSVLPKIRPIVEHMGPKTMSSDAKIQLLAYVLVLLVFLKRGATVKRVFIRASQLLLLRYVIQQLLMHVKLQDLTTSMLAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7B9</accession>
    <name>A0A8K1C7B9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7B9"/>
    <dbReference type="OrthoDB" id="115485at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel" evidence="2">
        <location>
            <begin position="164"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="464" mass="51725" checksum="5ED4A41D3B7744CB" modified="2022-08-03" version="1">MPRVRELRQRLERTKLQKDEDVQKHLNALLVIKDLLTRLGHCVPDAEMVQILLNSVPNKGEFGRMKTFLRYRDEEKLSDPEAVIACIKRAAEVEATHENVRNNQQRECFGYGSVYHLRANCPGETREEDPSPAPEPPRPSRQPRPIMFLAGDAAPHPTTGEDFWSISTATSVHVANDLDYFVQIEDASFVGDEIVHGAPLHPGHVEGMGRIALVTSINGLKKTVYLDKVYYMPGARYSLFSPGLAQEQGMEVDWDFERGIGAKKQGQLVIKEARHPGRGSSRFYAKPVEGTILVDNRSIASEERGVKTQEDHSGVLVPGSFFLTDNIVPRRETGEDYWLFSTATIVHLVSDLAYFMNLRDMRDGDGGDLHGGPIDPKEVAGVGTVAMIAQVDGWEKTLVIDDVHYMPRAAYPVFSSYAMGRHGYMLFSADSGMTIGVKRGSDILVRWLRALAFASSPSQWKAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7S0</accession>
    <name>A0A8K1C7S0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7S0"/>
    <dbReference type="OrthoDB" id="1112980at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027921">
        <property type="entry name" value="NOPCHAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38489">
        <property type="entry name" value="HISTONE CHAPERONE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38489:SF1">
        <property type="entry name" value="HISTONE CHAPERONE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15370">
        <property type="entry name" value="NOPCHAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="224" mass="24465" checksum="E8409A61005F3E47" modified="2022-08-03" version="1">MCLTTPTQLQLSEGVVHEGVIRNERDPVVDVRLAFVTRHTHQRRLVGKSCHQAGRRRYLLPAMNPTDSKSKPAAFPKPPTSALFSRLEAFLPLMETENKKLEEAIASGRGDEHNIEVPEPDATSDNADDNDEGASDDDVDMDDNSKRSDKPGKTPVIEMNFALGLMEEGGSDSDSDSDSDEEKDEIDLGATIAAAGRRQDAVETETTLKLAPAPAKRPMIVELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8C5</accession>
    <name>A0A8K1C8C5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 DOCK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DOCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47328at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027007">
        <property type="entry name" value="C2_DOCK-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043162">
        <property type="entry name" value="DOCK_C_lobe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027357">
        <property type="entry name" value="DOCKER_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317:SF76">
        <property type="entry name" value="LD20667P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14429">
        <property type="entry name" value="DOCK-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51650">
        <property type="entry name" value="C2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51651">
        <property type="entry name" value="DOCKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 DOCK-type" evidence="3">
        <location>
            <begin position="467"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="DOCKER" evidence="4">
        <location>
            <begin position="1529"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1219"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2054"/>
            <end position="2104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1232"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1266"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2060"/>
            <end position="2078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2094"/>
            <end position="2104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2104" mass="235824" checksum="831FE7D480456065" modified="2022-08-03" version="1">MDGGRVGEEERLRHEAQRRVKGDDSDPADVQDDHGQLKSVRGENGGSPRPNQLQIDTDVTDARQNDDDCANDDEEGFGIEPGTLEVIEMSQREWIHPVKPPIPVSSPAQAPILQEFGRVWKALRLRTVSSVDGLLKKKELDPEQCLLKNYDPRFPISEATFPSEIEIPGFLQPRIAAEEALAFLVRPCLQFTLGIVEPLYCRLVIYDTYLSCRVTEEFVFVLPPSSSVTSSRNSIVPSSQVKCPYALFYILPNHIPQNLHLVLKVSKVLVGEGDTATAPYCFPDKFVSETERQKLHERNTDCIRRLGRYLQPVAWGTVCLTEGANKSMTMYRQRVTMSDEQRLAVLSDAIRGTLKERVVPSACEISVEKIESQRFEDSKFRLKVLRTLGKDAHKMPSWPILEIYDPSSVKVAEEETPNQQQDIPEGADAAASESAFIQCREIQPLAHPSSMESFGLHGGGPVGLFYVNTLYLYPMHVDKLQFRNIAVRIQLLQKEVEYVCGVDSTESKSAVVDAVYSPTYELASCAYTQVNYHQRNPQFETEMKICLPEQLSLKHHIMFTFYHVHCKKLQPKQPQQELVGYAVLPILRCDGALIQDNNYTVEVMLPPPASKNSTSGGVISLPPGYVDAARNNSAEGVRTTFTCRTRALSSVRSQDSAVAKILEPFQSISLRPHDSISEAQVIQNLIELDLADKPSIRHFFLPVVRFILAYLRFGSSAVREVAFKILLGVLEKSKLIPQRSSRPHEVDPILYQFVSLVYDEQMIESLAAWVPKAKTDPSKAEKKPQSVLHGLVTEWTKLLVNGSKAEESIAIQKLSLENANILLPLILKSMAMQRCTKSNVALPTPSTRHDEDALLEDLLMELIRNTTITSKERGLTLRKTVNQSVANFCRGMFLISTSILPVRVINYFLGWTQQYSNDVTVHILFPFLNILMDFEFFAVVNAFKSPAVTTPRRRRGAWLARLIFLRLLKAVDEEKEDNNRSTALQLLRRMFVMQVYHPQHQSTEHQELIALMYFPMISNVARFTTDGKLLATSDSFDPAEKGENEKMIEFRRELLICVAHLLSSVSLPYLTWYFRQNSPSAVEPTGKETNPPLSPTAALLHYRKLVEETKAKARETRRQSVIQRTVQKVLETVDASDRSSTFDEIRVHACLSLVRQMIENFLVDESALSSLQHLLAPDLLSRNGGKGLLDIEMNHKHRRSRHRGTSLGQEAMLMHRTSFNAGNRSPNAKMHSGSGSFSSRASGAPPRLTSQKSQRNWGKAHASIHRQPSVSGSGDTKTTHSSYSISQRGDEEEGIDYETNVRNLHCIISETALRALRTAVDQFEWILRFIEKPLDYRTNMTKDEGKITVDEAFSLLGSLVDIFFLLLKRASAIDCLCTSPEAEIEGVDELNDDDAGCFLAELFRHLHCFLKRFEKALFATRISGLPLIHDQSRIILLVGMSATAKMASVRQLAAALLCRLILVCYEQTGSFLLIKRALLKGFCANFFSPSVVQIPTECLREAVELWRQYAFPEDQVTRGFELQLIEFLNSLNSQIKVFEMWIGAMTNPDEVCDIEEVEDGIYRVVQGVSPHWLLDVKMQWMEALLQLHASRKRYAEAACCRLEIIAFAEELSAEEWNPGPEWLIHELRSASDLAEKASWHQRMIDIDERLLTALRAYKRFTEYQATLKHLDVLTTQFLGNTGGDLGPTASAFYRVSYAGDCVPASVAKNEYVYKRSKFVSLGEFVGDMKASLRSRYPLCERVDVLPESKPFPAFDGHPNVIFMRITSLEIVSPNKQQPLDGSTFRFSTPYTLGNTSYGKTAEQMKRVTYLSTAHSFPCSTTRQIVCSKQEELRCPIDNSMDDIRKRCGLLQDEIDKEARGRTDLKTLTLVLKGSVDTHVHGGIPEVIDAFLARKQEAFPPLLGTDGNSLEEEHAMEKRLEMAELLVRFLGFCWTCLLISRAAHRRSAASTPTHSSASFFASETHLVNPSTSSITSSPAKAPGSSPGPAPLLVTVLTNASVTLQEDDAHISALQIEFEKSFLVLIEGMISKVAFSFPHEQDLRVLLSQTQRLRSNSIRPTSAGPSSGSSSMILPPGSAVMPPPAPMALPGTPTGRQSATSSFHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C983</accession>
    <name>A0A8K1C983_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C983"/>
    <dbReference type="OrthoDB" id="114791at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="920" mass="105228" checksum="6269EACBA8FC8278" modified="2022-08-03" version="1">MRQYDHDDEEMYTEQVYRVTNAMPERYPRSRVRPDELVMEDTLEEEFKSGFEAGGVDEHVAMERLPQRVRYLKLNTTVLPDLIVPYLYGDRQSRINAIMDQTGCTIDYCPLSPEEQGQSPQSMSYMMNFLVSAETVPQLEAACKMLRNVVDRVQFHVQQKLAVASSMRRRSGSIRHEAPERIEDEVEYLHGGVYGSFVKAEPIVYDQMPPREYPHRYHQEMLLDDNDFDMEPMWMENRRYTVPDPSRRFRPVRTVYRRVPVKAVEKLGSKSLPLGEVADSYGKSDLDAELDIPDAVGIWSTDAMKSEEEVKRAVKEENHLEIPVEAPSYVSPFFNDMVNESSTSVAMVGAQRRLLRELAKSDPYYYVRPLKLTKGPRSIGSSSCSFGCFGGSSTKWERKVVSQVSSRMKWFDSVAYSLAKVSGGKELLSRKKMNSTIRKLHLVALQLHCLLSHLYCVRKRLKCREIDSLPTALNNSYHEKRMNGYKSRLKLMVHQPQLHSNVPEELLRDTFEFFPELLLCVDMWGNDLRDGVAEKPSDVLSLKIPRDLLERARSRFFDFEGDKNGLLQSICEELLNILCLWNDFKWGESLESLTINAIVTFEERVKSSIRKILGIHSTHLLATWSEKILARPDLLYHIRMTQPNVYYSDTVPTGVFFQSGDKSVSLSSSNQHEEECEDSSESNDSWIPQDKTNDEPTSTVIFRLDDGLRPLRVHDLRSVAGKNLEQHVLKWSDVYNIRQQYQSLANNLGTFVRDSSTTESPSNILERIASSRNILNEAVQTSEKLALHSVGHQLPMELREGGEGGALADIESTDDSADEAERRQNENANLGGHLPTEKTEQPDAEMSPDVNEEETEPLDDQTDVKDLIEIVTSTNHDVTEICSQRSRSARVREKLQGQSVELARQSIQIFHNFLQASNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9D0</accession>
    <name>A0A8K1C9D0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9D0"/>
    <dbReference type="OrthoDB" id="129949at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="973"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1021" mass="109514" checksum="67A3E88DEDDD0DF2" modified="2022-08-03" version="1">MASGLMSMKASEASANPRVSTTNAAVASNKSWGEDVCLQKLHPQTNSSNVYKFHSWLDGNDRTKLFKGGAPKQQATSDGASAADRVSTSKEGSSAKVLSNNKIRKLEKQMKRKERQEKKGQEVGAMGNLPPSKKKRRQTQSVASKRDKQLQEEAPSGSVHPQHDKLPAKHAVDLDSLPRNIQDDMASQVLRTQQQLLIRNAASNAPPMLVPRPQPTVVAISAAAPISKKRPRSERTGNVRHRNVPEAPASPAMDSSPTNSAYEDSVRADLLSTLGGVVTWRGNAKPESGDSIADSGNVTGKKKRRQPRCAPQSAAPEPSAPVAIAHAVEFPEPLQEPSPVVRTESETVMIFCKRDFMRFQAVRLWKKYQEQKKKRDVSLATITGRRARYQNRDQTDIVTTSVPPTNAPRKRLRKAVNKDIKQTQVTQVVIELDGDDSDDDGITVQSTGLSEEATLTVTKYGLERDHSVDAQVMEVIDLLVSKLCCIEDVTTTEAVRDDGAAGTLDDETLVEDLQTDMDYSDVNGLPITPASKDISGHGGATEVSLGGSGMGSMHDEPMGEVDDVCGAKKDDAMGECVGESTSESMHDETVEAPATGSLRDAVIEEEMASNTCVSTKTSDGAPTPPIESVKLVAVHEGVITATLQQNCEMAEDEDTCSSDSLLTTGTTISNEVVEAMEHLVESVVANRLESGKTEADDTMPSASAANAQLLVIADVVMTAPSTVDPQAIPTIDILSTQEAPVDEPMDVIMEDLEGADANNVALVNTFSGEESSVPTVISGEHLSAGVEEGATETEVILNQRELATEIDMEQDGMVSAVVGELVESVVTAVGEEASVTGSESAPLESTQDSTAIEAEPKLEASRETGPSTLSPVTSPMFEIVCVEEEPQQAEETLDESMESATCAHQRSQEVVAASQEEEEPIHLALWSDEDDWSYTAKMSQTKVDNSVGDSETQSEAQVLSEEKVVATPIPIPILTEKGNQRSEDTATRVNSDPPCDPMVLSTKSLEMKSSTKESEESTQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAJ9</accession>
    <name>A0A8K1CAJ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAJ9"/>
    <dbReference type="OrthoDB" id="124611at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="59504" checksum="4AE4BF8032266E9B" modified="2022-08-03" version="1">MPSKTSSPRHSRLSYLVNSTSMIPSVMTLRVEVHYMRVILGTLVALAFVSSIVLVFHHGVEIEARDYASEGKLIDDYNSYSSIVVSAFGRPLELFIELVVQLFVLRFASSSILQPETPWHIRGGVVCSAAALAYLVNNGFNALNAQLRPPDIQPVISAADLSVAMNNNDSWDTDEITNVSRVVSEATPGNPISNTVLRNLVSLASGRKTVGEGLKKDSSSNKTYEFEVQNLRKIYSFTVGRLEWKLEDLSKTFSAKCNVQDGAKCAGLQHLLSEKTSRLVASADDLPLGLLAPFPFDDNAIQRILALVRIQEPSASAMTTTSGMYEVASGDILFPRNVDSMTSDASVRLDGSLCVRWVKDRLHSVLNNHFYIEHTLQPAYTAAMLFLFQDATTKVVLTLSNNRESLKFSQNIQRMAVRLSIPPINMILSLVGCVLCGLGVFGALLYPAFTTKDPLQDIDSAHVIAHVMLDESKFPPLILRRHLVDLLDDHSKRSEVEAFVIQALALAPQEYHDGKARIHFGIEQRETRDSSNSLVVDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBE2</accession>
    <name>A0A8K1CBE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBE2"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="25"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="30684" checksum="61D815D6430157CB" modified="2022-08-03" version="1">MTNYKQPSVFVPHGGGPMPLLGDKRHADMVEWLKHFQRDFVTTKPDAIVLVTAHWESEITQITSSEAPELLYDYYNFPPESYEIKYPAPGHPALAKRIHDLLSDNGIKSEMNEKRGYDHGVFIPLKIMFPDADVPVVQMSVYSSQDPEAHIKLGEVLRSLRKDNILIVGSGLSFHSFGLFRGNPDGANAASIPFHDYLKESLVDTSDSIERRRRLHNWTDAPFARQVHQKEEHLMPLFVVAGAGLEEPCEEIFDGYVMDVRTSGYLFGKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCE1</accession>
    <name>A0A8K1CCE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCE1"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000011">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000032">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="50"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="340" mass="37598" checksum="CACD5E38CD75730E" modified="2022-08-03" version="1">MFSRQAGATAVETTPVALPWVEKYRPKNVDEISHQEHVVATLKTSIQNGQLPHLLFYGPPGTGKTSTIVAVARQLFGPHFRKNGRFLELNASDDRGIKVVREKVKSFAQGAISSSAGMPPFKIIVLDEADSMTGDAQSALRRMMENYSKVTRFCLICNYVSRIIEPIASRCAKFRFAPLEKVSMASRVRYICQEEGVVIGDDVVDSLLECSNGDLRKAINTLQSAKQLSGDDHISRDDVLAVAGLAPPEILESFWTSVASNNFDKMKTDVENILMSGYPVNTVLQQLSTDILNHTKLSDVQKAKLCLRVAEADKKLVDGASEHFQLMDVTSYVMRIYHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL3</accession>
    <name>A0A8K1CCL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCL3"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000024">
        <property type="entry name" value="ATP-dependent RNA helicase DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000767">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF118">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="53"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="242"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="683" mass="76567" checksum="1C753D2CB40FCAF8" modified="2022-08-03" version="1">MASMKRPNQDAVAFKGKPFSGKPTHDQSHKRACSEIQRTKQRLPIFAHRSRILSTLQSHRVIILVGETGSGKTTQIPQYIFENNNKECIAITQPRRVAAITVAQRVCEEVNRNGLGQTVGYSVRFDDMSSKATKLRFMTDGMLVREALLSPSLDRYSVIVLDEAHERTLQTDILFGVVKQALRKRKDLKVVVMSATLDVGLFQKFFAESNPGVLQIPGRQFHVDVFYTPKTQPDYLDAALITVLQIHLDEKDSNGSILVFLTGQEDIETLDTLLEEYARSLPADTLKLEVCPIFAAMPREQQMKVFEPAMKGVRKVILATNIAETSITINGIRYVVDTGLVKQRSFVAKSGMEMLLTEPVSKAQAWQRTGRAGREAPGVCYRLFPEETFEQLAERAIPDIQRVSLEVVVLQLKTMGIDDVLGFDFIEKPKVTSLVKAMEKLYALGAFDSSGQLTERGRQMAGLPVEPMYAVMLLKSSELGCAEEALSVVSMLSVESIFYSPRDKKELAAQSRAKFMAYEGDQITLLNIFNAYIQCNVKQRNKWCRDHFINQRAMIRVESVRTQLKGYLEKLGLPIGSTFPDIDPLRKSIIAGFFLNTAMRSLADGAGGSKTAYKTMNGQSEIVKVHPSSCLFMRNPPPKWVVYNELVFTSKYYIRSVLIIEKEWLVEIAPTFFKKLSPVGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD15</accession>
    <name>A0A8K1CD15_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD15"/>
    <dbReference type="OrthoDB" id="191609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="32161" checksum="B267C4F5A2441F41" modified="2022-08-03" version="1">MRKFEDCWVVDRTMFEYVNQGGCSCCGVTHQIMDVAQLADRCSDWESDDEKKEQFSPWPTFIHEEILTERARLRVVMKEDMRQYKAFIDTHMKGFSAWWQQLDESTKNRVFQVPDEDVMDYFKSHAKVKGSYEIVLCAVMEQLRHFNETGYKDGRIPPECCAEQYLQNRRSCFVMDPKYVASADGAVNFCEIMQILGGPKLLPLRLTRDPAQNNQAEQEVAQSVANVQSFRSDRRLLRLVIFRKFADVAMRKYLREGTDSKEKAAVDDEDGNQATAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDU0</accession>
    <name>A0A8K1CDU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDU0"/>
    <dbReference type="OrthoDB" id="58460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF9">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47088" checksum="C6BFED628DDD86CA" modified="2022-08-03" version="1">MIAVAIGLPVEDGKVRWRDPVKKHLPWLMLHDKYAEEHVNIGDMLSMNSGFGAVSDIADMFGAFASEREYVEALQYLEPDHSLREKPDYANVNFVTLGQLIESVSGQTWYEFLKQRVWEPLGMKNTFASTLLAPSEGQAFTAGHFVYDGEVLGPFDITKDRETFLKVGMGQELNAAGSIVSCAEDMATFIRLLLNKGSVGDVKLLKSASTIAEMITGKVTATSTVAQVTKMGLCYDPDGSTLAAGYGIDLIGQSIWGYPYFDKSGDVSTQQTRTGFAPTEKLGVIFMANSQVPDPHASFYLDHYRTYVMGVFLDVPNQILDFEYQKLRAADQLQPPFPGAPARSLRFWEDLPIRNLPIRNDRADGDSQLTVTLALSSGPLYYLGEVEGMPSMKIFLGKFALGPAILPASVSPSGHYVFNVGISYQKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE01</accession>
    <name>A0A8K1CE01_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Selenoprotein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010752</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the selenoprotein M/F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE01"/>
    <dbReference type="OrthoDB" id="1910009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.50">
        <property type="entry name" value="Sep15/SelM thioredoxin-like domain, active-site redox motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038219">
        <property type="entry name" value="Sep15/SelM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039992">
        <property type="entry name" value="Sep15_SelM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014912">
        <property type="entry name" value="Sep15_SelM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077:SF6">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08806">
        <property type="entry name" value="Sep15_SelM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438939" description="Selenoprotein F" evidence="8">
        <location>
            <begin position="26"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Selenoprotein F/M" evidence="9">
        <location>
            <begin position="117"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="251" mass="27315" checksum="3F684BBE5AE471F1" modified="2022-08-03" version="1">MRVVSLTTLCALGVAFYAHPLGASASTDEVVPSAKASDALDAHSAQANEECVAHGFDAEGLDCRLCGRFEAFLSDMLAAAGSVEKTNASKRLVTQCRSCCTDLEKIDLVAQQQYARVVLEVCTCKFGRYPKVANFVHAHAEKHPRLEIQYLNARHPHLLFYNEAGEKQEEVSIASWDEETISEFIVAKLKPESQLETDEATSASTKPAIDEEDEDADLLSTEENAEGADDSVEEAEDEDTVVEVEVTADGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE84</accession>
    <name>A0A8K1CE84_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE84"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000556">
        <property type="entry name" value="Probable protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="235" mass="25200" checksum="3DDB376FE6BBFCE9" modified="2022-08-03" version="1">MAWRCSALSNEGLVDNLARAGIVQSRRVIHAMKATDRAKYMATATGINVEARVAYMDAPQHIGHRQTISAPHMHAYALELAEAAVGTVDQPRVLDVGAGSGYLSACLGRMVEDRGGHVFGIERIPELVAFAAKNIGSADPDLIERGVVSIEQADGWSGLSSAAPFHFIHVGAAAVEPPQALMDQLANGGRLLVPVGPEGEAQVLLEIQRTDQTFTQRKLMGVSYVPLVREQRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEI9</accession>
    <name>A0A8K1CEI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEI9"/>
    <dbReference type="OrthoDB" id="541403at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23525:SF1">
        <property type="entry name" value="NODULIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23525">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="3">
        <location>
            <begin position="312"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="55926" checksum="3B4010E68DDCA70E" modified="2022-08-03" version="1">MWSLFDRLEHNVKYVFLFTIAHWTANSITSQQLLPGYLYAITGSNESVGSVSSIRGLTQLIFALPAGFAADYLRRDRVLTFAGVLGVITAVLMALAFGMGDLKLVNVSFGLWGMFAAFQSPAMEALFADSVPVGRRSYPFTLKHMVQNVTLVVGPLCAIALFAEYGDEWELQGVRPLVVFGSLVALISVVGLFQFDDDQAYENKEYMISVERQLQSIERNFDAELSMYNPVDIEQASHHLGDDGDEASRLVSARKSRGASEMSRLLMAGEPLSRKKTVYLTHPINIGTMNEEGDEGNNETIPVFCGLDPSHVPFVLFAADFIVSFGTGMAANSFPVFFDNEFGLTSIEMQWLFVGQPLCIAASSFISQVASRYWGRMPVIVFTRFVGAINLFLMSQVSSLHLLCALFLLRAAMISCSEPLRRSLLMDFVPQKQRARWNSLEGLSMFAWVGSAVIGRLLVEAHGYRVCFFITSLVYMAGVLLELLLVPLTRHAVEFPTSEPPMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEL9</accession>
    <name>A0A8K1CEL9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exportin-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEL9"/>
    <dbReference type="OrthoDB" id="2215036at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="1">
        <location>
            <begin position="125"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="2">
        <location>
            <begin position="324"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1216" mass="135921" checksum="218B5F3EE41BB6C6" modified="2022-08-03" version="1">MDPQLYHQVLLAIQVNHSHVAGQSERTAAYAFIEEFKNRDDCALYAVAIFKAPTASAVDVNGVPTANDATLSPIEVHTRQHFALHVLEHYVLTHWSRLPVADQLHLRSELMVMLLQTVPSSEDPVFIKEKKVALIAQIAKRQFPQRWPDFLTDILQVWQVGTPSQIELLLMILRSLAEDCVSSSFNSTIPPARRKDILQGLNACLPQLFPVIYSELEKQYAAYQSDVASRTSSKRLIGAALEMLKEFLDWMPLDKPVEPSTNLIMVAILLLGDEEFRVAAAECLDVYVSRSFGKENRRIMVQTITQIIEKVSTLDLQTLEPDLEANLVFHKKVNDILVTWGTTQLDVFLQDVGPQEMGLLMSVLQNLCRLFAHPSLIVAETQIVFWLNALKNKAVLQHPDIAAVVARLREISFEKYFKLGSPDRDEDTPAVECSRVEYDDHHEYMAFFGNFRGRLYALIRVLVQLDANTILKMLHERLPFVLTQHSAGSDHLSPRGLCSELSTAFLYHEGITSLIDCVVKQLPNEAIENPENRQILQAILNQILSYSSQDPLLKYRQLFVLAAFPKYYVLDGAILTSVFETLFVSIDFALPGEDVHGHMSNETMNVRRRALASLVAICQAIPAHILPVLPVLVSKVQELFAGDRVLDSEGVLLYEMLVLVSNSMQNADERAQFLQQIAQDPISLWTSAEMTNLVGSAENVVGAIETAESNPEVRKMLAKIVKTLTTIYAIAKRATVSNGIEPFAPSWPQILPNVVALIRTLHSLQQPVLKDAIMKTSTACWLLSVSVDEIAQLLGGKHQLEEEEVAKLPAASKWSKWHKNIRDVSYHIMGTAAYQPSVYASGQMAAYLQSGILSDLDAMDHRHMKNALASVFLPFLKSCPKELYPSLLEPVLSTLLTHLGQRFATSFVKPEAGQKSPKTPWTALVVGVEDAKRDVAQEKMLMDLTRQVMEFLESAIDAKTVVGADTDTPKHVTQPEDEYLRDYILLQSPTLPFLVGAILVQIVSWKDTMSCRKATILADKLVNMLHMGTQFHVMLGRDIFLASLQALLQEDAGHVKEDGLKWELINLVRNIYCRLTLGLVPVEECKGIDPCNQPQRPVSMLCSAPREILLSLPDVTALSIDGLEGYLREKHSVKSQKNSFKEFLEVPMLALKREQALASASSSPVAASLLLSGRRSSKQIEDLPERLVIPMKEQEAAWKLHETQNTSLDAQSLFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEM5</accession>
    <name>A0A8K1CEM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012642</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEM5"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000011">
        <property type="entry name" value="Cytosolic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="431"/>
            <end position="432"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="53768" checksum="30920EF14EBFA8D2" modified="2022-08-03" version="1">MAQELRFPDNFIWGTATASYQIEGATDEGGRGDSIWDAFARTPGKVINMDTGARADDHYHRYKEDVQHMKSMGLKNYRFSIAWPRIIPAGVGAVNEEGVAFYNNLINELLANGIEPLITLYHWDLPLALQTEYDGWLGGEFIQNAFVEYARVCFDRFGDRVKRWLTFNEPYCATYFSYGTGIHAPGRKHKGSTEAYIAAHNMLLAHAKAVDLYRKEFQPRQNGAVGITLVSEWREPAAATDPQEQKRNAEAAERAVLFMVGWFADPVYLGDYPQVMKDCCGDRLPSFTDDEKKLLKGSSDFFGLNHYSTFYTRPSKAYLQGVKNETTDITLDEGAVFTSDPSWEKTEMGWNVVPWGLEKILLWVQNRYNCAGGIYITENGCAVADKTKEDAMNDDFRVNFYKAYLSHVHKAIQQGADVRGYYAWSLMDNYEWSEGYAKRFGLIWVNYETMERTLKKSAHAYSDIVRKNAVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CER8</accession>
    <name>A0A8K1CER8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I NDUFA12 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CER8"/>
    <dbReference type="OrthoDB" id="274641at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007763">
        <property type="entry name" value="NDUFA12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12910">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05071">
        <property type="entry name" value="NDUFA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="223" mass="25461" checksum="7CCEA5C9B7BB0468" modified="2022-08-03" version="1">MTTLLAGKRLVQAAATTPVASVSVNVQKRTFYGVYEKYMEAKKRYGWKEALWKLSFTNDIKFGYKVGEDEFGNSYFEDPTEFSGMQRYTEFRVGNKEETDASQIPPQWHVWLHQTTDAVPGQPGQDAKSWEKVPVVAESHAPYENHVGPSKPFKMHPTLLRARGYGVDGVFTKAGEPDQYYVQPGHLLRRRHGEKRKLFEEVDYNNPEASKDTTGLLRPLDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF70</accession>
    <name>A0A8K1CF70_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014538</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF70"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="37"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="45"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="175"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="25028" checksum="D55C274E256C4403" modified="2022-08-03" version="1">MTISRTVYNQLFEHTEEKEQVIRLRPTDAKAGAVVMSSKHRIQMWTKEEHERFLEALEKFPAGPWKRIADHIGTKTPRQTMTHAQKYRQKIFRRQRGLRNQKRSPNGADGNMAVSPNGVADLKHAQGEAGAAGQNSFGLLDILAYSAAAAQSGQLQQVRDNGATYPQGQQPAEFPAQQMYPQPAPAADAAQSSAVSSPTSSQASSSLCANSHLPPLSEILQLRGSQVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF83</accession>
    <name>A0A8K1CF83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_014553</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF16">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY MEMBER 4-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="720"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="849"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="949"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="989"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="73"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="406"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="724"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1050"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="645"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="681"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW61092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1295" mass="139639" checksum="5EA159374489797D" modified="2022-08-03" version="1">MKTETQAVAELDTGAVAAGAKYYELQTPKQAKDSQFKYNDADTDGGDDTSIKLVSIFELFSFADRTDKILMTVGTISALIAGISQPLQIVLIGDVMNAFNPMDLPDAAQLRSNVNTVALNFVLVSIGVFAFCFLQVACWSLTASRQAKHIRSAYVNAILNKEIGWFDVNEPMQLSTRVADSTVTIQEGMGRKVGDGLHFFSMAVSGVMIGLIKGWELALILLAFMPLLAFSAFASMRRLADATQTGIESYGKAGAVAQEALGNVRTVHMFNAIQHFVTKYGLALEESVNAGIRKGFAVGWGIGVMFFVLYCTYAAGLYFGAVQIGNDQLDGSKCTGSGCYDGGKVMTVFFSVSMGAMALGQAGPSIQAVFAARTAAYSVFAVIKRRSAINPQSEEGEKLEQVKGKITLDSVTFAYPSRPDANVCRNYSLTIEAGETVALVGPSGSGKSTIVSLLERFYDPQSGVVQVDGVDVRGLNVKWLREQIGLVGQEPALFATSILENIRHGRPSATDDEVKEAARMANAYDFIMEFPQGFATEVGERGAQLSGGQKQRIAIARAIVKNPPILLLDEATSALDTESERVVQESLDKLLAASKRTTIIIAHRLSTIQNADRIAVHRDGQIIEIGTHEELMRIADGQYKALVEAQNRAAESSSGETSPPLSPSHEVSGAVAARRRSLSYSAHSQRGSFHKMPADEEGSEEAPENKVPLSRVWKMASPEWPFLALGGAGGIVNAAVFPIWGVILCKIITMFFKYDKTKDEMLDNARAWSIGLVALGVVFALSIIAQHYGFAVASQKLVGRVRLQTFQAMLQQEIGWFDLDENASGALVSKLATDSATLQAMTSDTLNQGLVNVTTLAIGLGIAFYYSWQMTLANLATLPILGFSAFIQSKQLAGTINNRENNEADLAAGAVLAEAISSIRTVASFSMEKAINVAYVTFIDASKKTDIKVGIMGGLTFGMAQGLMFLNLAFLFFLGGKWVANKTVAFDDMFMVMIVLVLSMFPIGMAAQNATDSTKAKKAASSIFQIIDRTPQIDSTSTTGKELTTVRGELEFQHVAFAYPSRPDAHIYKNYNLKIRPGQTVALVGSSGSGKSTAISLLERFYDPSAGSVTLDGTDLRSLRLPWLRERISLVSQEPVLFAGSIAENIGMGKPGATREEVIDAAKKSNAFDFISNFPNGFDTDVGDRGAQVSGGQKQRIAIARAILRDPEVLLLDEATSALDNESERVVQESLDRLLALKQRTTIIVAHRLSTIRNADLIAVTKDGAIVEQGTHDQLMAIPNGVYKGLVARQMNSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFC6</accession>
    <name>A0A8K1CFC6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFC6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467649" evidence="2">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="31165" checksum="42C88CF34ADB9E65" modified="2022-08-03" version="1">MLLLALMFVIVWGVKDAAAASNIETNDPLYNLLVVRAANTLNQVEVAMNETNADDWTRNRLFPKLQEDFRKQLEDGEATPKKLQALLTQFLARAELTNIGITNTTYHVVRYDELAPSSLEPMASWKVLMYSCVEALKRFQLFTYSNRFAAMNFTGQAWIMENRSIDEVIRTVWEPFVENVTKTEGADLIWSSTKVRGELQALLNTDVTYLERPKPTSVAPLTESPTPPPTEKPSKSAFIRASTTYKDEIRSSLPASSGSMQALASGLLVGMTLFHAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFI6</accession>
    <name>A0A8K1CFI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFI6"/>
    <dbReference type="OrthoDB" id="95392at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538:SF1">
        <property type="entry name" value="VWFD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="57107" checksum="CAE2AC3B322A1A76" modified="2022-08-03" version="1">MRAGIAATGLVTAATLLGYQFNNVHHHYHAQLAKHRMLTSVQEASSLQVHVTVKRDSMQMFGSNEYSLIATPVITTEADGSQSVRYNGVTAFMKDGVQHTYRLVDGVTYYQTKNQQAGFAQESTECLTASSLPPVKDMLEALNAAKPITKVESSESISCEGKLLSTSLNGSPFVICAASDASKGFKVYGSDFNVDVTYLSSKIEIPKPAMSAEQAEACAKTPAAAKLTTSTANLITGTTSGAVSQVLSNQEATAVLPKATCSCTGAKRPCLFIHGLGQKTDGGLADSFDYFGDIKNHAPCCSSIKFALLDTVNNAWYSDTLENKVCNYALSMSSSSSTSTKTVANTIIVTHSMGNLILGGAIASGKCSLASTSSWVGLSGPMIGSMGADYLQTTCANGGLLGGLASLFGGCPANTAIKSMSYEGEKYCPADLKTKYDAAQAAYTSKVSAVMCSNAVDGLLSTDQFVLKLGASVIPHKSSENDGVVEYQSCRAGLATSKFSNTYTSKFYVTKLNHLDTTFRHGDALIQTSQMPVKWFECLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFL0</accession>
    <name>A0A8K1CFL0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFL0"/>
    <dbReference type="OrthoDB" id="2148946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001562">
        <property type="entry name" value="Znf_Btk_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46270">
        <property type="entry name" value="ARMADILLO-TYPE FOLD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46270:SF6">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51113">
        <property type="entry name" value="ZF_BTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="36"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="303" mass="33054" checksum="672F664D0604A645" modified="2022-08-03" version="1">MANIHYTVTRLSFPPPPSVLDANGLPLLNLQLDAIFSYQWGSQSTVLDVYQQGRVANLRAWFDVYGYMQGNVNSAMAAAVESVACVVVFVTDKYTQSVNCQLEFLYAAHLHKPFILVFMTDWRALALPSWMTDAVGTDFDIYPSRVDNAKATPDHVLALDFTAERINGLPMTTVLFSAIRVLAAERNNAPSPIAYDGSLLLYATTSALHHAMSSSNSVNDTQTPSSVVCTRCNTLFHPSVASSLDGCRVHSAYYTGGTLLAGRWVCCQETRTDGPGCQPATHTAITRTWTCDPAYGTYSCQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFM5</accession>
    <name>A0A8K1CFM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010973</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFM5"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="240" mass="27953" checksum="60483D10BBE99BE2" modified="2022-08-03" version="1">MFQSPQFTSDTGLGRIAVAAFGLGFVMALHVALLIYYAVAIGVDATDRWHCVALWSVYMIALCFFHLSEFMLIASFRPSTVSYESFLLNHSKEYHLALVVSWVEFWLQVWLVPSWKANPTVFTTGVVLVVFGQWCRILAMWTAASNFSHRIEYIKRKEHVLVTHGIYRFIRHPSYTGWFFWTMGSQVVLANPLCTLGYSFVSWSFFRDRVPYEEHLLVQFFPDEYPQYRQRTISGVPFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFM8</accession>
    <name>A0A8K1CFM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucosylceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFM8"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000109">
        <property type="entry name" value="Glucosylceramidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474739" description="Glucosylceramidase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="5">
        <location>
            <begin position="105"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="6">
        <location>
            <begin position="470"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="60830" checksum="5B99ED1A70DE8BB7" modified="2022-08-03" version="1">MMRSWSFLAVLALGFVANNNAVDAACNNFSNRFQKALEGVCVCTEASCDTVSNAYLTTPAAQLSVYTTSKAGDRLAPSTVAINTTKPTTSDFIIEPTVTYQKMIGFGGAFTDAAAINIYKLKTTSLQQKVLDAYYAESGLQYTVGRIPISSSDFSTSIYSYNPVVDDFDMKHFSIDVDRAPNSNKLDLIKRALSTTKRELSIFASSWAPPTWMTRDNSTLNCRVKGVPGEPYWKALALYYARFIEEYQKEGINIWGITVQNEPGKPIIQPSVWQSLRLTPEEERDFIKKDLGPLLKQKSPDIKIIAHDDQTADIPDRMAPFKDADALKYIDGIGIHWYKNLDFFFFGLGGDYGKLVDFHNKYPDVFILGTEACEGYLPSWLGTGVGVKLQQPEQIWYRAENYARDIIEDVANFASGWTDWNLALDTNGGPNWAKNFVDSPIIIDEVSGTEFYKQPMYYILGHLSKFIPAGSIRINLKSNSKKNWDNIHRAAFLTPEKRVVVVFCNRRGDPATVAFETPLQQSVTVTIPARATQTYIFQASAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFT4</accession>
    <name>A0A8K1CFT4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_005145</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFT4"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000579">
        <property type="entry name" value="cyclin-dependent kinase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF171">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="4"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW62527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="339" mass="38024" checksum="1307490EAFF069C2" modified="2022-08-03" version="1">MEQYEVVTKIGNGAFGEVFKAKHTPTGDVVAIKKLRLNDDGRLRVLPASLFQEIEALRQLEHISIVKLVDVFADGTSIALVMEYVETDLFSVIRQKKKKAFTDDEIRGILRMLLGAVAFCHDRHIIHRDIKPGNVLVSAHGELKLTDFGLATVYVGPEKKYSHQVATRWYRAPELLFGARNYAEGVDIWGVGLILAELLHLVPLFPGENDIDQIYRVTQVLGHPQHASWPEVVDLPDYNKVEFPPYKAIPLSQVFPDATPSVVDLLSKLLALNPRHRISARDALRHPFFFSGPVQPRVPLPVSILQEHEQDKSVLGSESHDDSTDPFLRSLGTPLPLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFZ0</accession>
    <name>A0A8K1CFZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFZ0"/>
    <dbReference type="OrthoDB" id="115213at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424778" evidence="2">
        <location>
            <begin position="24"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="41137" checksum="D3EBB86374A9B5EB" modified="2022-08-03" version="1">MPSSHALQVVAIVSALLLSSIHGYTCSQSEAQDVFALYRSAAARSGCAPYATYGTNGAVTIDWSCTTTSCTPTIQQLAYQLPNCESSDGVNRKAALENSLYTQCQLCTFDQEDTIMALWKGAAANSACSKYATAGGIWFSWPCSATSCTAALRDMADKMPSCFVDGQNERARILNGISTCTGTTVSTKTPAPASTSSDASNTPSPTTAEPEPTTPSPIDAISNSTIDTPAPAPSPTSKFSSSSCSSTDVGDIVDLYVEAATSANCKQYSTVSAFSIYIYAPCTSPCVVSNFRNLADSLPDCYYSYDSENKKEQVSEEVAKCKYVSGRMLSSSATEEYIKIEISSKDAIKTSNTTNPVPAPSIALGYKHMSGFALAAALFTHFLVIEFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG26</accession>
    <name>A0A8K1CG26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005474</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG26"/>
    <dbReference type="OrthoDB" id="377083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="543"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="560" mass="60743" checksum="A3321805996E227B" modified="2022-08-03" version="1">MRWKERLRAQHAQATEAFVLLLLVAWVTRETSGYVARAETNATTELLPRMLVWLNVLAIATVFWSLFAREPVPKSMQVLARRERDDGHVIGGVLPVLALLSRFLVQSSGDDSGNGTTLLYAWTCISAGLSTILKIVAFQSSGVIPTLVVDGFLLPIVFSLVSIESGSRFVLPTLCRCLIGFVFHFGRLALPRSFTTGEALIVAQGIGIAVFDLLLVTFSKLDEASRIILPTHTLVVWHVTEQQREHHQLALQVGVIGALLICVALTPLLSSYGTSSPHAVAPPLPAAGVVWFLGTVGSAVVLIVYPWSCLLLDTWNPISWLINFLLEDSARWLLIVYWLACLVIFVPSFAVISRVFKLRQIVARKLFHFLVVLMFVPAFYASPSMLSLSYGVALAIFCLVECIRAVSLPPFGVIIAEFVQSFIDHREAGRVVLTHTYLLLGCAVPLWLAQGSASTNPLAANAGVLALGVGDAMGAVIGSTFGRRKLFGHKTWEGFSAVLLSMLISALGLPQSGFTSPQELGLLVFGLALTSVLEAATAQIDNLVLSLVLFTVANLITLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH84</accession>
    <name>A0A8K1CH84_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH84"/>
    <dbReference type="OrthoDB" id="111646at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="233" mass="25661" checksum="7CCAA4325CC43FC6" modified="2022-08-03" version="1">MPTRVYAPMLRAGLHRSSVLSGRLQSVPHAPRSGVTPAAQLLATRAFSVRAPPKQTKPLDTKRILETPIVEDADSTLMRWIGRGSATQMYCTFIFAGKLIYEADAAANLYEVIATSGAIASASVCVFLGAKLWCDRIVTDIASCRNFGEKDEFVRLTIQGTLAKYALYVSVKDFILLQHDKPDSYKFRVGARNFTLDLANAKCTSRKSLETLLQGQPLVTRKGKQPKKPRNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHN2</accession>
    <name>A0A8K1CHN2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHN2"/>
    <dbReference type="OrthoDB" id="207411at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904294">
        <property type="term" value="P:positive regulation of ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044235">
        <property type="entry name" value="RNFT1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15860:SF0">
        <property type="entry name" value="LP20373P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15860">
        <property type="entry name" value="UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="447" mass="49760" checksum="3B6A7DBE3659BB3A" modified="2022-08-03" version="1">MDASSPRENDPETAAMDARADVPVPANVDDSATNAGPHGPPEDQAVQMRLLQALPQLSQWLQGVNTHPGLQRVQRMQSELQRRRSSFEQEGVNDVDDTYNEYAELLRRSSSSGEESSRRRGRQDSASLFEIRIDTGNPSENDVTHPTATQEAPRDNAANPTGSTSPRSNASSDGETSQHEELSTLDELQSIFRRGNHTLPFIALFLVYFAYQHTLGIAVFIMGTVAIMGLDQRLVAQITLKENASRMYLFGIMAMCCLDLLALCTISGDPNPLHHLTSKVQATGDGSDPTGAFWQVLWIITVNDFIIRLFGLALKAFVALIPSEKWVPGCRRSASVANTTTSIDDDHDEDRRKASRATIAFYRRKRKIYSLIEMVSIFTRSFLAGIPWCSFYQLCASKFMADAFTFGYIFTKGFLLGSQGRRIYRVMRSLRNLGLEHAVLRPGMARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI31</accession>
    <name>A0A8K1CI31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI31"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="521"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61042" checksum="42AA5EF644C24616" modified="2022-08-03" version="1">MLPHRRSPWMDVEAQRLALVAVTLVVDLFFTGVVFGWAPLLLMLLDENQYSELCSENEVATPCVAQENRLNLMFALAAVTANAASLPVGVFLDRYGPKATTAVAGVVEIVALVLLAFADSRTFDVFVPAYMLLAFGGSLTMMASYPVSFLVMSHQTAILAAISCLFDGSSVVFVTLYSIQSLFRLSRQTLFIGFACLAVVLYVLFFILWHLNERALRPSASTAERDRLHTEEDLSCSSPVSEKAAKLLLKSHYVDYGTLNEAHLVDEYDPEEIHELYRSGLIESKLAEVPVLDQLRTFEFVFILLFASCHVLRTNVFIGTANKLLANYGDASHDFLYTKIFSLVLPLGFVFVPAIDYIVEQRGLTLSMVFTNTIGVVYNVLVLIPILSLQCVTFGVFTGFRAFLYAVISSFAAKTFGLKNLGTLIGLIFSIGSLVGLLEYPAVSLSNHFVDGDLATVFWISIGLCVALFPLIGVYRKRDNARRRKHQQLLAHFGSTFLSPELQTHTPGLSYRRSPCLSTPSVEFVQSPRSPKILSPKKNKRSPPSHRRSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI99</accession>
    <name>A0A8K1CI99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014191</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="670"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="941"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1007"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1074"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1133"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1156"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1489"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1521"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1567"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1622"/>
            <end position="1641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1703"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="345"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="789"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="1262"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="1828"/>
            <end position="1918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1410"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1418"/>
            <end position="1427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2065" mass="236777" checksum="C1222C21E42C4D97" modified="2022-08-03" version="1">MKRMSNSFVMLSMPQMGGLVVNVRSALDPHSTFIKVWHQVLCAVLAYDLFFIPFTVTFRPHEKVAETPEGVMFYVTELLFLIDFWVKFNTGFYEDGSVHRDLYKSRMKYVRSKGFVLDVIAIIPWSLLPTELGASQMWLEVPKLLRLWRLPMFSSNLDDVYARHFEALKIFKVVITMLLFSHYVACIRFSFGYDYDHNNQWLPKFPNTPHTPRRQYLMSLFWGFGMLTGFFEGELPHSFSQFVFTLSIGLGGFSVFTYLCAMFFMLSKCENGHIEASEAHINQLKHIMAFHQVPKWLQAQAIEYMEQYSTNAESNDREVMRMLCPSLAKDIQVELMQDTMARIPVFIGCNKNFIKALTDALEMLALPAHCTLFSAGDEGDAMYIIQTGVLDVIIGSTKVSIGYPAFNDQYSRQLADVKENVWWARVLLQESIRADSKVRLWWLVILQVNLIYNWVFIPLQLAYPVMDIDTWYINVPNTIADIVLVADIYLNFNLSYVKNAETITSPTRCARRYFREKFLWDFFVVFPYSALGASWIRYPKLRIPRLLRVVYLKKHLQEVDKMIHLNNRRKLLLFGGLLLVLGHVVACFYFSITLFEGFNPGYDSWIPTEDVMLVKIQQGLFADVNNLTFTTGSSMLHWIAARQYSRSLYYATNILTGLGKTVEPSNDRQYGAALVFMFSGFIVTAIVVDNVQKRFTASAYEQKEFFAVRTRIQLFLRRQDAPFAIHHRVNSFLDYWWSAHRGARVNDLLMELPLGYRREVLRAICAPALQTLALLGGVRPVWKELEMAFVDRVQFVLYGQGEFIYRAGENAHSVYFLLRGAVKLRLQGTPNKNIPEGGFFGTCALNAEEDNNRYTTDAVASSGCVLVQLLRDDGEALGDVFSHFDIALRQLEQRLFENKLARFASDNISHGADTSPPSRWHILLHSAWDPDSIGAMVWQSWLFIAMTVQWVLVIYHIAFGIGRDHFVALDSVTVVLELSFVLDMYVQSRSGYHEFGNKVMDLKRIRYRYFHSRTFIIDLIALVPFFMLNWAIPATRYEAFNVNKLVRLLKVPGQFRQLEQRFLKRTTELRLFKLVYYAFLLTHVAGCMYFDFSSHLSLMNLYDPNIASRDIDFGTTKWVLPASFKDADVSYQYFSALFVMYGLMSAAYQGELPKTAMQSIFSVVTMISGFFLFAYVIGNFADIIEMMDSGNREFNDRFGSVRQLMVYFSLPDTISSKLRTFFYFRRFHTITQEHLIESYLSPSLVTDIRLFNLQPMISKVPFLSGMEASITRVLVAEFNQVLVLKDEYVYKFGDESSDMYFVFTGILAVLSPARHKKSEIARRKSRLAAGRSMGNWYDTGVEAGMLAQLGELVSGDFFGENALFSNSPRNAFVLAKTSCILYQLSRQSLERIFDRYPLWKKQVLQTMKVQQKQRRLHSRMDRQREDESSVSGRGELVEDEENSEDISPAGMVFRPPLPISRKGLLKNAPRSLDWLTHGTPAQGHAHLRWLRLVMGCTVFIAFIIPYRLAVDNLDRQTVVCMVLRAVEVVCDVIFLLDIWVNWHLQEGTLSVEFYEQDLRQSYKRERLVWDAIASIPIDYLVFAVSGSAWFRLMSCVKMMNLVYYLNEVNRQSVSYEWTRLRAIWLLYIIAMVWTGCVYLVIATRSGHGTNWDAWSPSTAVEVANEDNPSNEQLILRFLRGFFFATTAFVKKCRTFFPETTDQAAFTILASFMGVLITAFTIGEIASLYISLIRNQVTFRKNQISVELYLARYKIAPTLRDRVRFFLSATWSAHSGVNYDHVLAELPSKMRTEVVLHIAEAPLKAFLEAIFRPLMRTDGNSMGSLLQLLVQELKFEAYPRGEYVIVEGVLSSSMYFVVRGQLVSSSEKAAVPFRSTRYRRGQYFGEKGLLVLSVSQVSVRAVKACDLFALSSAALLRVLQSHGFVKLALAVAEETLGCLRATTPSGVLPYDMDTWKEVLESVLQRQRREWLSRSTSSLTTELTGGNSGNSTTQWGALLVDVQDSDKEDHGLARFTALLELLTPHGVSYDHPRSTVMQALSSDSPRASGKIRLREMVLKMSKPISGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CID5</accession>
    <name>A0A8K1CID5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CID5"/>
    <dbReference type="OrthoDB" id="203202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="15292" checksum="3E9000E7BD79F6E1" modified="2022-08-03" version="1">MSESKQSAASTGVDEEYLRALPVVEVDSIDVSPNPAALTDELNLEVDFRLDKPVVHGVWEIQLGEVEAQNYREGENHFQFSVPHIDVASIEPSQLTNCGLLIASFKNDEGDIMDLKMVVQVSEHRDGLQRIIYNPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ25</accession>
    <name>A0A8K1CJ25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ25"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="17756" checksum="1486DF21B5444999" modified="2022-08-03" version="1">MTDAWARLATFSGLTGPKGYSVLGQDDGKLSQPLIGGLDDSSDEESPHDVEYGSKRQWYDETEYAAPQKKTVEDTLRAVLQALLPSVLWPSQAPTETKDARISELKRASPATLTTPLRASVRSRRKAETMEDIHERALLKIAALTLALSTWLIIAVYMHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJI0</accession>
    <name>A0A8K1CJI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJI0"/>
    <dbReference type="OrthoDB" id="113194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="235" mass="27276" checksum="14CF4588A855222F" modified="2022-08-03" version="1">MHEGERRHDQDDIIEVEITDILTSTEETIQRWQHAFRLEMMSQEEKQHEQNRQHLDRIHALQDALNESKRHISKLQRDLQDTTTKFEAFQALTLKAQKAMEVTLREHSQYWKAICNDLVVEKRNMARRLSEERGKYHALKEHMEMHVPATSLEPSADNRQDVRPRASSSQKSSAEDRPPSPLTPPLSSQPTKTHPTPSENTSKHIDSSMPPDPPSFRRYYLTKKSAGVIKPRSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJV3</accession>
    <name>A0A8K1CJV3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63743.1"/>
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        <property type="term" value="C:snRNA-activating protein complex"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
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        <property type="match status" value="3"/>
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    </dbReference>
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        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="157"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="163"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="209"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
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            <begin position="209"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
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            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
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            <begin position="264"/>
            <end position="314"/>
        </location>
    </feature>
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            <begin position="18"/>
            <end position="132"/>
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="151"/>
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    <feature type="region of interest" description="Disordered" evidence="6">
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="788"/>
            <end position="809"/>
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            <begin position="41"/>
            <end position="52"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
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            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="798"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="809" mass="86646" checksum="0BC67A10B4E185B2" modified="2022-08-03" version="1">MSTTATATNLSALGQALGQTSISSPGSLGEDPMSPVSLSMTTTAAGKATTGTRKSPKKRERTDSMKQLTPMPAAQRQRHGSVGDDGDYDEEEDDDDEEDGDQLGDEDDSLNADGLSDASASEPSIKLPVKDRTGSAIAGVSRAHLISNAVKTAPPAKEKSNPRRWSKHEDESLRLAVERSGERNWKAIAEQVPGRNHTQCLQRWTKVLKPGLIKGHWDPEEDAKLRELVAEGKRNWGQVASLIPGRTSKQCRERWCNHLDPNINKGAYTEEEDRIILEMQARLGNRWSIIAQQLKGRTEDAVKIRWKSLMRGKKAASKEAKEQAEAAGGTSDKSATLNIVTASATAGSNDKLEDKPAKAKAARTTPTKPKARVPSPVAKGVEVPPPNNTVEQASIPTAYQQPQIVVQQNVPVMNADPSLGSSIDSKHIAASINSYMQNVNDLVAASIQNFKLNQNYPGNVSVGVPTSTPQSASVPVSSTNMLGSTHPSMMAQTTISPPGQPVYSLPPNGFQGMPQAQQAYGMAASYQMPTNLGLPPNYVLPTSGVHVMNGQAPGQFPVTVQAQSSGLAYGYPTGMVNVATSAARPVSIQSTSGYPTASMTMTQPGVTYSSGMPVVSNPYGIPTSMMPQSGMTVPGGPTVVSNTDGLAPVSAALPPHPPSVNSKLATPREEWGSSQTPRSHLIMTEGHASAYELFHQQRLRLMLKEREKGMSLASAPSPGQAMLTKELRANKERQKRQEMMQNGWKSAVEAIMTLNNDVLSMDDNDNLMEKVSLSALDPTDDELLDTTVDISIPPDTPVDVDDPVNLDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJW1</accession>
    <name>A0A8K1CJW1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW64010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456647" evidence="2">
        <location>
            <begin position="20"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="32423" checksum="81AABC4B87BDC862" modified="2022-08-03" version="1">MKVIRALIAAALAVATTAADTPVSVCRDATYTIPASRGAICSGAGAGPAGKACPLKGDISTADCHPYLPSFNGEKCVAKEDAVCEIVTGTTWGCVFPSVGCLKQPTPCPLATPCPLATPCPLTTPCPITAKPDVTPCPITSKPDVTPCPITSKPDVTTPCPITSKPDVPKPTTPCPITSKPDVPTSAPVTPGPTTPCPITSKPEPTPAPTSAAPVTPGPTTPCPITSKPEPTPAPTSAAPVTPGPTTPCPITSKPEPTPTPTSAAPVTPAPTSAAPVTPAPTSDVPTPAPTTVAPVKCETLGLAACLKQKETCKFVGGKCVPISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKJ2</accession>
    <name>A0A8K1CKJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynamin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009396</name>
    </gene>
    <organism evidence="3 4">
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        <name type="common">Mycoparasitic fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
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            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="116917at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="2">
        <location>
            <begin position="43"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="973" mass="107110" checksum="D53449199FF26F80" modified="2022-08-03" version="1">MSEFQVVAKDGVPLGIGDALLHGFVGQFFKQTEGVKTLLQDLALDLPQIVVVGQESSGKSSVLESLAMMPLFPRDESICTRMPIHLKMRHRQTRTGVSGSGSGSDSPTSEVETPQIKMRLVFSDGRAPVESDDGFQTEEVAQQMRTWMDEIVRGTNSDGSAVTGVVDHVLEIEVTSSQVPTLDLIDLPGIVAGRLVDEPEDMMHQTRALVEKYLKMPHTLVLAVVPAFERVRNSQAFQLVQQYGLEDRTIGVLTMVDRAIDVSNPKGPLVAVMDRLDEVSSDVVKLKHGYVAVKNRDTRTDQQPPLEEFKRDEVAWLEENLAGYVEKKLASSGILASKLEMLLAEHVRTTWVSQTIEKLTEGIENTGARIRDLSVDPQTVVDSLLVAEDTSTRYDLIRDLLGMKLAQAIEVADHEILPLVRVVTKEVKQKQSLMSVLPKTNRLLRRSALWAITSREAEISYFVEHFEDIMSSIALRLIRTVRRHLTLKLSTDEDISELDLFQTHRFEELYSLAVLVIWEKLQTLRESKDTLLTQVTRALSQPSVSLPSAQLNAASAQESLRQTLKDVNEFLETSLGEMPISLSSFIEDGDTPSTATKTTDASPFAAEASESQEKPSVIFKFGGVASPAGTNATGSLPKSGFSFGGVTSTAGSYEGNPKSGFSFGGTSSASRTSFSFGRTEAPCTGGIRGPPEPIELSSIAVPKSLREGLGFISSSWLQPVLLLLTEHALGCELRRHSCQVLGCSRVRRVLEREVTCARPCTCSGCVKAEEICTHAVKATVDQVIDGIATATTSELTQLFEHSKTCLQGDTCKNDSCHEARRIMTINYNCVATDCHHCKLVKNLGRSMLEERVMAATHTWGIPTEILMDLLATPSKPATKQDVQDIVELKEAERRMFTALGRHVVAPMLQALTDVTNLDFHLLAYLQNYPDVTAKPKHWFSESNQGERVRLNKKLSRLKNVREGLETLAGLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKZ4</accession>
    <name>A0A8K1CKZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vitamin-K-epoxide reductase (warfarin-sensitive)</fullName>
            <ecNumber evidence="3">1.17.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_009045</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.4" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKZ4"/>
    <dbReference type="OrthoDB" id="17010at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047057">
        <property type="term" value="F:vitamin-K-epoxide reductase (warfarin-sensitive) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042373">
        <property type="term" value="P:vitamin K metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12917">
        <property type="entry name" value="VKOR_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="entry name" value="VKOR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042406">
        <property type="entry name" value="VKORC1/VKORC1L1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519:SF5">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Vitamin K epoxide reductase" evidence="13">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="165" mass="18668" checksum="C7FDF1203F24AB6A" modified="2022-08-03" version="1">MRVRRAGRQLVFLGVLGALVSAYGLYVEHQKHKHKDGYKALCDSEYFSCSKVMTSEYGSLLLYHGLVSKGSLFDVPNALLGIGAYGLFILYPVLRYLPFHQHFYVLASICSLAISAYLAYILAFVLRDFCLVCVSSYLINLGLFWNSLQLTRGPTHRRRHAHKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC4</accession>
    <name>A0A8K1CLC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Leucine-rich repeat domain, L domain-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC4"/>
    <dbReference type="OrthoDB" id="160860at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035450932" description="Leucine-rich repeat domain, L domain-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="70908" checksum="8579159BC88D33A3" modified="2022-08-03" version="1">MSAHGVLVALSLIGSLGQRRLVFFPFQDDDVVAAKKTCAMVSTLFGRFGLFGVESRYFDTMMIVRESVETILQSYQAYRMSLYVPRVWLNRLYVALLVLNCWMTPLVVIFFKRRPLACRLLHLLCGSLLDLMSSIGIPLILLPTYANDFDLNAGGLDMTRWYDDVWYISAFSELQLVFVSSWMDLFSRLVFYVGVIGGMKSMKDLLRPKTNKSGIKRVGPTLSPPTNNATPSAVLPSIPASENSAIVPTSQRVEPTPMDIHSFTPHRHLNATRLRRLKHIIHVGFVPWGLVVLILHLQAEQQEVLTNCLMQVRPWMTEKPACALLIMDCHQYGVSGYEKDIAPYWDHADEATVARILIRHCPRLHMPSILTAFSRLSAIKIYNSTVVEWGDEAALTNRHHPTIGKLLVLRSNLTDGKLPRGLLSSDFPLILKDIEFQISNLKSLPADLDTKWHSGSYLVFENCQFDHFPLVLLRLVPGAISLAFNWIATVPFEVFRVNGITHLNLAGNPISTLSKLAHETVVGAGSIVSLNLIRTNVSYLPRWIDPLFNRAGSSLSVLLCDSPFCLHRGELANGIRNHFPELDSMPLDHLSDVMSVTAAELITLDRKVSCAMTEIYYYPYGHDDALHSLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLG4</accession>
    <name>A0A8K1CLG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLG4"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="420"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="516"/>
            <end position="520"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="520"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="665"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="665"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="800" mass="90676" checksum="E2DA51A4DE4658E5" modified="2022-08-03" version="1">MLRGGFLSKRSVQVTPKRANSQRVIVVKQDVHPICGHFLNVNVEREFQKYYRSEIQSGVIVYMLAMIVFSILFTVGSGHDALAATLVYFAGITDPPTILRTASQRVSWFSNATQVTLVVVFPLFAFGCVVFLARYRNDLFWMTLRIDPMQLVLLIFYQFVLIPVMLATAACADLEDSYLDDFSAHGQGAWNKQTLAFLGTNALNIFYVFVFLATCVASCLLRMQFAYFLALATEFAIIVSALSGVAFPHLPIRWGLYIAFLLFLALLTRGVWDGELAHRREFLSQSSLINENRRLSNQNIEMKEELSGKLNYQLHYEMADILRILCQIKVKMNSHEKKEIDKIITALVSNEDLFEVSLDPSKTEHEEEVQGWLHMMALKESPASVHGRQSVDLGEDPGYSPRPILKAQVHRSTQSRRMSRNPENEDKAVEMLTKFYIKTVSEEPEDFSRWLLTSLLTDFFVDMFYIDEHCSAPLQAVLITCIEINDFIARLGLDCQKLLAFAGAIENHYFKRNPYHNCLHAGAVVADMHFYLRRITLTIDDITFFVGLITAAAHDISHPGVSNGFLIATRSKLAITYSDDSILERMHVAELYRILSHEKFDIFAHLDGPVKSDVRKLIIQMILATDLSRHFQHVSKIKSRKFVVTDNHQGLDVSWIMETMLMLSDLGHTTKPFAYHQLWANRIAEEFFRQGEAEERNNLPISPLCDRRVANLPRSQVAFLTLLATPLFEATGDALAIEEYNVVMTNLRGNIAAWQSLISRSDSVHNSHTTPRPSSVMKDRDISATELTPVVPAALNTSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLK7</accession>
    <name>A0A8K1CLK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Alternative oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_011422</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="16">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLK7"/>
    <dbReference type="OrthoDB" id="16906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.140:FF:000002">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005229-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW64542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="37159" checksum="70DB6699589882E9" modified="2022-08-03" version="1">MLSIAYKRLLTRSTRSLQAHAPVLDVLRLDLLTDHRNATRTRGFTTTETKTPAKDVTEETPMIAHFTQSSTRHPLTTPEEPTWENPVPHTVYDLKEISEIPLTHHEIKKTHERVAYLAVKALRTGFDIASRYRGPGGAMKEKDWLHRVLFLETVAGVPGMVAGMVRHLRSLRSMRRDYGWIHTLLEEAENERMHLLIFMNMKQPGPLFRLLVLGAQGVFFNLFFITYLASPRTCHRFVGYLEEEAVKTYTGLLKDIEDGHLKEWSDMVAPSIARNYYKLPSDAKVFDMIKCIRADEANHRDVNHTFASLDQVKGVNPYLAKAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLL1</accession>
    <name>A0A8K1CLL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable pectate lyase F</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_011463</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLL1"/>
    <dbReference type="OrthoDB" id="94626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="234"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="31583" checksum="979CE8520767C77C" modified="2022-08-03" version="1">MPTGTWPSSKGKVTYKAPYVVKKGTVFDGGMKTYERSDITCTEGEGGKADAVFLVEPGATLKNVIIGKNQKEGVHCEQHDCKIENVWWDDVCEDALSIKGGSSSSVSTVTGGGARYASDKVIQQNGPGKVTIDGFYAYDFGKLYRSCGTCGNIPRQVSVSNVLAVNPKVSVITVNKNYGDKATLKNVKVVTTSKKPICQWSQGGSSPKNLGDGPSGTLCQYSTSDVYITKEARDSDVEIEVSSSTDEYAGQEEEDEYNVETEAPTTDDEYPEELPGNATEPDATKKTGCKTKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMD5</accession>
    <name>A0A8K1CMD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMD5"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019396">
        <property type="entry name" value="TM_Fragile-X-F-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568">
        <property type="entry name" value="FAM11A, B PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568:SF9">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10269">
        <property type="entry name" value="Tmemb_185A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="39379" checksum="CE396353F9566DA5" modified="2022-08-03" version="1">MIVEETIPTETRKGEIPTEDHESAENSTGEAADNSLRAKFESDRDLWVLRSLMLVSTSFVLGILLLTPIFVCLRVDGDVSWDWSVVFIPLWVVDGIVYIILVLDLSVAGPSDLPRWYKKFLLAKSLLLLVVQVFIVKKLDKSLDWSVVVVLVPYFCYDVLTIIGTIYRSIKTSKEPVESDNTATHVLLKLLHGPHWIHLVPMAIRFVQILLIALRIDGHLGNASWWLVFIPLWVALLALVASVVGGVTAHSIIGATLIEDVHVRSAFLTLWAESTAATLAMVVIVVVAPFIILVARLASGSFSTFFIILPWLLITTAMFLGGVGIYVWYVLHMCSVSGAVDEDGVNEPYTTVAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMX9</accession>
    <name>A0A8K1CMX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMX9"/>
    <dbReference type="OrthoDB" id="167142at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="610"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="730" mass="81599" checksum="E73971DE5ECE4409" modified="2022-08-03" version="1">MRWLDTTLRHLSHALHMDHQHLGRYSIEKLHLFDVYQRTSTTPRVCLVTFLTPLPTLLALIVMDVVPLNDPVLGPSLNAMAFVRSMHSHALMTFVTLLPMKQALRLNNDEYSYLTVARIAVATSLTVEAACLTLAFVYRFPLPFRELIGLPIWTMSVVVYNYVFAKETLCRHWRGLKRYLPIVSVQVMLLYLFLALSVGFGYLSFVPQTVAILVFPLVKLYLKNLVWHYARALDDISTDVTICLVEIGGALFQTMCMQLVTSIWLNALVVVTDIVQAVVEIRAYMKMDYLSDGKQTVTTVRKIIESSIRMAGGSGLSAPFRSTRTRTRRSLDGSSETTEQSMAKSGRVSPKSTKVLLRRQSSARLARSSDKSTATTTTRVRDSTVVSPRLVAEQARRLAESRAMSVYIPSQNLRRKSSRRLLDLNQSRVDISDRHLSERSESGHSDAQPVVDSGLSVPQSAAMQQETTPSPNAVITPVPEFVGSLRRKSSTRTPRAGVASRLRRIVRRASRSHLRSQHKNSVSATATFSNLQAMDPQTGAMVHPIASTGLGASSRRLQQYQPDKAPLEKPALSLVAQPGTLPRRSSVVMVVGIVVPRRDQARILEQTLQLLFACEVLLFVEYMEVVILFLYALCLRCDWILPNGQYNLFVRGMSDADVHLMLLNSLVYALLELASLLAMYYVMKTKYGVSAFCQLAFVLGRYWLTLQGKLVGAFIVIWNAATVHQGTAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN32</accession>
    <name>A0A8K1CN32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN32"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="41"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="274" mass="30893" checksum="E04E2BD98C3693CE" modified="2022-08-03" version="1">MASFDFHYHGKRRDVSEPATLNLENPAAPKITHPAQNWTKTSIEEVQKQVRVLRDRNPNAPVFGIGHSMGGAALWMAEVANPGTFDGLILFEPACNMHELPNSEMIIPVYVSFILSGQYRWDSYEEAETYFRSTKAYARWHPEALAAFIQGAVVKNEPPDYLFGIQSAYTLACHPHIEAAHYMGQPCFLSMEEMGRVRCQVVLQYGSRTQMFPLKASQKLAHTYPLLYRVDMPLPKATHMMITEDPDTAAERIMSTLHQFPAFGSSTESAVPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN92</accession>
    <name>A0A8K1CN92_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN92"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="722" mass="83005" checksum="E9CE0270EE13D507" modified="2022-08-03" version="1">MSMRLKPLVPASPSAQDVENRVLSSLVLPVKPPKWISSLVYVAIWLCVLAVHGACCTYFLFMWWFYRILPKSILTRYLKLYDLGIPDTEYALVSRVHVLFFGLHAFSGVAMVLWSLRMRRLSFGPWYHKVQRSPRRQRPRSLRWFPRDSPRLSRWLSRLFGRRGLLGIESPYYNIVHLLRQLLETALQSYQAYRMSLHVPRVWLNQLYISIMILSCWSISIIKLVKMRDPLRERMLLILCDILLDLVASIGVSVILLLSFLPDFDMVSLSMRYFLWYNGFWIVHAVSESQLILVQSRMDLFTQAMFSMGLLWYMESLKDLMEITLQRRAIAPRVGPPALSVPTPPAIETAKVSPPRMVTFPRSRGKLWLKVVQFGLETALVMWGIVLLGLHIHVASRATIHQCLMQVRPWLSHKSACALLVVDCYAAGITGSEAEATDVWDDVNEKTVLRVMIRHCPNFHMPPQVQAFRELRGIKFYNSTVAKWTKDAEMTQTFHPNLLTVLLVRTNATNGEIPRGLLSSNIPRRLMDIEFCVTNLRALPDNLDKIWHTGGTYHIEYAQFDAIPPSILRLQPRQLSFVGNNLTRFPFEVLNLRGLFYLNLAYNPISSLATVPYQHLVDNSSLGRILLTHSNISSVPRWLDPFFRRKYGSRAPLIVLYTPLRTRLAAGQSLRSQADDLGIPEAERSFVMNLTAEEAAAFISCSVPATPYYYPLPYEDLWNSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNG5</accession>
    <name>A0A8K1CNG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNG5"/>
    <dbReference type="OrthoDB" id="565040at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748:SF1">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24826" checksum="0D365470C4519835" modified="2022-08-03" version="1">MVTIVGFGSLLSEKSARSTFGDAMTNFRLARMRNYRRVFAHPGSIFFERGIANLATKEISSLSVEPAEGRSFLISVFDLPESMLPDFYEREEEYRIVSADFEELDGTPGGQGLMCTRWTDEEYIQHRGQETFDRLYKRHGVDTIWGWDEHSGILPCRVYLRHCLLSVKKLGDMVYEDFVQSSFLGDRKTTIKEYITANPSIMKELPPAHLSERYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNK9</accession>
    <name>A0A8K1CNK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNK9"/>
    <dbReference type="OrthoDB" id="125603at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="227"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="523" mass="58380" checksum="2271E7591F3B8C03" modified="2022-08-03" version="1">MQAAAIVVSAIVPGGDALVKVTELVSELHGSKPMFESLLKHLQEVAPRLGKIINSTVSTEQKAVQQYQELVTNLQTLLEHHLKRNFVLRAVAYWSSLKDEVQQFKTQLDQVKDLMDLDREINILANFEQQQQLSQQASDAQAMDIAALRILIESQPAEFAQLIKRERVTVADLSDLKNEIKTNGAAYTEEDARTLRTVLESACAALDVKLPHISKWYLPTGDIIYDDDDPFSTNESELRALYTGTIILGSKVTVKPVRTSDNPDDVKQFNEHARMWHELRHPHVLPLYGANNSSDPLLLVLGRAELGNFRDYLATHRHRIWSLFLDAARGLAYLHKNNIIHNNLKCNNLLVTAEGVGVVSDFLFAFVRTSSAMSVKPQAPSYHWKAPEHFDPKHPNGRVESDVYALGMCLFEAFTGSTPYSDVDEDTAIERIRSGQLPTVPSGVNVPTEAADLIKSMCARQFQQREKLHNVIGTLERLAARECARNGLAQCDCASPSCSACHRSVRQQPANSGRSYMTRSDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNN2</accession>
    <name>A0A8K1CNN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3 7">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003695</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="3 7"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNN2"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.870:FF:000010">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="76"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="9">
        <location>
            <begin position="466"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="618" mass="68460" checksum="C23BB666BCC7F67C" modified="2022-08-03" version="1">MASTMFRRAGMKRMALGLGVSAAGFSGLSGAAILTAKEKQERLVAPIKCEDGSTIVPYQVPSRQTQLERLKKEHFDVLVIGGGATGAGCALDAATRGLKTAVVDANDFAAGTSGRSTKLIHGGIRYLEAAFMRADYAAFKLVLEALEERAFFLGAAPYMNRPLPIMIPIYNWWEVPYMWVGAKAYDLVAGSKQYVPSSHYINAEEAAFQFPMLRKEGLKGAVVYYDGQMNDTRMNVSVVLTATQNGAAAGNYIKVEKLLKDENGKLCGAHVKDQLTGEEWDIKATAVVNATGPFTDGIRLMDDPKKQKICVPAAGVHVVLPDHFSPSRMGLIVPKTTDGRVLFFLPWENATLAGTTDSASDITMLPSPTKEEVDFIIDEANRYLAKDVTRNDVKSAWSGIRPLVRDPRHMDGNTSKISREHVVEVSDSNMVTIAGGKWTTYRRMAQDAIDKLVEVVPSLQSKASPCKTRQVEIIGADRIGEVCNKKFDKITVTLRESYSMDKDIAEHLMRNYGTRALQVAELEKTGFLDRKASDHPRRLHPKYPYLEAEVVFAVRQEYAQKATDVIGRRMRLAFIDSDVSSKLVPRVVHMMAELHGWSKARREQELKECEEYLATMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPC5</accession>
    <name>A0A8K1CPC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="12">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_012457</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
            <location evidence="1 12">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPC5"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000828">
        <property type="term" value="F:inositol hexakisphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000019">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="15">
        <location>
            <begin position="69"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="14">
        <location>
            <begin position="308"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="737"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1071"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="737"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1073"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1106"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW67341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1122" mass="127576" checksum="214B7986623F3A72" modified="2022-08-03" version="1">MDAPLPVDATVDAAMDVEQPDETDKQSEPEVESDEHTSTGGEDDEDASMEESDDEEEEEEEEIVDAMFTIGVCAMDKKARSKPMKEILSRLPRRLFRVVIFGNDTILNAPVEEWPQCDALIAFFSTGFPLEKALEYVKVRNPVVVNDLDKQHLLMDRRDVYRILEANSIPTPRHVFMNRESYMGQPPSEMVEAEDYVEVNGVRITKPFVEKPVDAEDHNIHIYYPMNAGGGCKKLFRKVGNRSSEFDPSINTVRKTGSYIYEEFLSTQGTDVKVYTVGPNYAHAEARKSPVLDGRVMRDSDGKEIRYPVILSTKEKEIAYNVCQAFGQTICGFDILRVHDASYVCDVNGWSFVKNSEKYYDDCATLVGKYLERSLQGSVSDPFSLAAFDSSSFRLEGGVAELSDPTMWEHEQSQQNRDYQDEELRCVLAVIRHGDRTPKQKMKMLVCHPSFLQYYEEKVVNSKKKDLKIKAVADLEQLLVVSKDLIRLYDLRDPDFLTFLNEREQTYGEDPNDRMKGYRTLRDVLQRWQLNGINRKVQLKPKEYTKEEGPNGEAIKRPSKLMLILKWGGDLTHTGEEQAERLGQHFRQKMYPGGDGGLIRLHSTYRHDLKIYTSDEGRVQKTAASFAKGLLELEGDLIPILVGLVLKSKDADSMLDQSGSEAQEIIMRVKQRLHHIIHRGDNCAELMDSSSRLIRSVAKALTTVDQPIKKMEIMHKLLGKLKDQLTKTIQEKAQVKAELTKKKSRQEQDPLTRVTRQSNNGSGPLERSRSASATRSRYGLRPGGHVHAYTSDEQKASRFSNQLPEEESLYPEPCGRETLDMMRERWAKLYRDFYLKKTDTYDLSKLPDIHDCIRYDAIHNSHLHLTNIRELLDIAASLAHTLVPQEYGINENEKIHIGSAMCRTLLMKIKDDLDLARGLRIGSTHRLNPSYAKNKHEIKSTHRSVRTRLYFTSESHLHTLLNVLRYGRDDCPVNAPVGEEAKKWVEEVPELCYMTHFVVRVFERFQYAADDPQRFRLEISFSPGADQDPLNEDVHSHLSVAPLKVISREGLTCQELVDYFADVIGYAERNNTSNQESNGHSSSSDSLKAVGPESSGNGEPLKRSGYLTSDASTSGDEPVAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPG8</accession>
    <name>A0A8K1CPG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPG8"/>
    <dbReference type="OrthoDB" id="168372at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="63932" checksum="1255579721985852" modified="2022-08-03" version="1">MSRVFPEIEFNASDFPSALTITPTAAQGRRPVGARSPTSTVNTISEAVVAAPAVVPAPVPTSAPTPAPAQPPVPVNPPPTTPSASEAVPNGTSSPPVVVVDDDDGDEDMVIDVDINGPYQSRRFGLVEFNPRDFTTVHDGLNIARRSNGALGATIAARVEQTRVPPSVSTPSSVPVSNPPPVHSNGSISPPTAPEPSASTSTSQPAPPATPSTTNQPNVLQPRRRRELHQPVDVKPVVHATPTATAPVASASSAPQNGLSFVISKPALGFCASELLGFMRDDDEEDDEEQARAELLEVVDLTHLSDESEDEEDDEDDEESGRATPEPASLTSRPNAAAAASAASPEASSSSENRSQTAQIEPAKRRRASRPMETCVLCEEKRWTKTLIRCENCAKYYHKRCAKEYGDDTVCWNCELNGMIDDSELTEDHRDEVVGMLSTLRRSSESDGEEDAAQHEEEEEKDEAGDVPRVEETEPPIAVLSSKATRSMRRWKEFLDVSTAKLDASYEETTKRISEELQDGRRRARYSKGFASKESFEAAMNEVMDEYADLQDQLDRETREEKAKAASAMPPRVGEPQSGATGTQPVAASASTPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPV3</accession>
    <name>A0A8K1CPV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="3">PPIase</shortName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPV3"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000059">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="182" mass="19913" checksum="47E9CDC3A32AEBC3" modified="2022-08-03" version="1">MDPLLNEALKRGNPVVFFDVAIGGAPAGRIKLELFKKDCPKTVENFRQFCTGEYRKSDLPVGYKGCSFHRVIKDFMVQGGDFLKGDGTGRISIYGDKFPDENFIHKHTEAGLLSMANSGPGSNGCQFFLTCAPCDWLDGKHVVFGKLLDPASLLLLRKMESVPVGPNSKPKLAITITECGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR54</accession>
    <name>A0A8K1CR54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="8">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Succinyl-CoA synthetase beta chain</fullName>
            <shortName evidence="8">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011949</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR54"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="36"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="359"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="442" mass="47738" checksum="6E19FA900EB4F78E" modified="2022-08-03" version="1">MFSRIVRTRAASSLLSLPAAQRQQVRRLNLHEYQSLDIMKGFGVATPQGIPATTPAEAEAAFKTIRGDRKGVDVVIKAQALTGGRGLGHFKNGFKGGVHMCTKPEQAREYAEKMLGQTLVTKQTGAKGIEVAKVFLVERVYMRREMYFSILMDRASQGPVIVASPAGGTSIEDVAEATPELIFKENIDITTGPTDAQVSRLAKNLGADENSQPKLEAMIRNLYNLFIGVDATLVEINPMAETADGEIFACDAKLNFDDNAGFRHKEIFEQRDKTQEDPREVEASQYDLNYIGLDGNIGCLVNGAGLAMATMDIISLFGGKPANFLDVGGGATESQVKKAFEILNNDEQVKSILVNIFGGIMRCDVIAAGVVAAAKDLGLKKPIIIRLQGTNVEKARELIANSGFKMIVADDLDDAAQKAVKIADIVSQAEEANINVTFELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR58</accession>
    <name>A0A8K1CR58_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007707</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR58"/>
    <dbReference type="OrthoDB" id="2150267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442948" description="G-protein coupled receptors family 3 profile domain-containing protein" evidence="10">
        <location>
            <begin position="22"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="729"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="776"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="840"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="620"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="957" mass="105554" checksum="DF21EDD5877B5EC5" modified="2022-08-03" version="1">MGLTPRLVCAVCSLLFAFTNAASKMAPNQLLGTCLTSDWVKSIEASLKLNASERDNQGRLVYPFLHAALRHQRHRVDDARTASAQAYSTGCIPVSTTIYGAGILLDGTTGTLVTPGSVNGSLVLELSGWMTHSLATLAFAILASEVYGYSVSLYDIARTLETTQRMSSVRAGQCTPTHGNVEVWLSGKEEILQVYANESYEAGPVGYVGRSGLYTTSEFVKDAMTPPTYSTKPMYADFWKDYKYNDDLIAAVPASRVRDTPSYFPAKTACADNTMGCLNGCSRTHACTLRDPTKECMVVVMMFASYDPGYLQAVMANLDIPAYFCFLGYGGAQSYVLKAVENKWPVLFYHYEPDLFHIKNPNVFERIYLPRPLPERTILTTSKFGENGYGEVTSNPVDVDFPDSPLVKFSSSALQRNPYIAALYSRFTLQPLDINNLLKSYADASASATEKDPTFRAACDWVKANYKTWSVWMDRLPVCTLADHIRYDVTGCTAGSTVREIKFAWHQPDPDDVSRPDNCDGGVAQLPASIVTSRSCEWILGDTSRWPAWIKKHPECDESFYNYSISECGANTKRTVTYSWLLPDPAKPSRSLECTGGITLPDAVSIDCEFMPMAATAFKVIVAIDMIVLCLLLAAIGFVYYHRDKPIIKRSQYELLILMIIGGVMICIAVVLYAGEPTRFLCAARPFFISTGFTTIFGALFVKSLRVYRVFMRSSLKRMTVTTLMMLKVYSFFIGIDILILATWLIADFPEPTVLTEKAQDFRGSVDRTECKSSSFLFTAVLIFWKAIVLLMGFYLSFLVRNVSADFQESIWIFASSVVVLVARLVIVPLAYVVKLPGPVFYVFLACTLMLSTGGVMGMMLLPKIFRLKEAGQSQRNSLTNAQGATRNSLTRATRNSLRNSLTSATNMGSAVAKYIVTAVDKTEGTQQDGRRASAHGVHNVAVQPLGVPGQPSMATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG7</accession>
    <name>A0A8K1CRG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005712</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG7"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000028">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006367">
        <property type="entry name" value="PRK08591.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01209">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="12">
        <location>
            <begin position="33"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="152"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="10">
        <location>
            <begin position="633"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="710" mass="78438" checksum="4CF4A3DEC392F379" modified="2022-08-03" version="1">MRLFTHTIRSAHALRSSLGQRLLSTASTPAQRSFRKILIANRGEIALRVIRSAQKLGIETVAVYSDADANSQHVKQATEAYHIGPAAAAESYLNYQKILDVCKISGAEAVHPGYGFLSENAEFARACAEAKIEFIGPPVGAIEAMGSKSASKDIMIAAGVPVTPGYHGEDQSFERLQEEARKIGYPVLIKAVLGGGGKGMRIVDEEKDLKESLEACQREGKASFGDARVLIEKYLRKPRHVELQVFGDKFGNVIHLFERDCSVQRRHQKVLEEAPAPHMSEALRKKMGDAAVAAAKAVGYTGAGTVEFLLDEDESFYFMEMNTRLQVEHPVTELITKQDLVELQLKVAAGQELPIKQEDLKIHGHAIEARIYAENPYNNFLPGSGKLQHLRLPPVSDKVRVDTGIIEGDEVSIFYDPMIAKLIVHGKDRDEALDNMIRALHQYQIVGLPTNIEFVARTANHPEFRKGGVDTSFLNKFGDEVLQPLPQFPTHAKALGAVSLLLLEQLRPRPLADFNGELHSPWSSESLAHFRSIDTLDRRFKLSHEDEHVSVSAKCFEQDSYEVTLTSEAGESVTVQARGEIDSNGDFEIRVENRKFLGTAVVHKEDLHIFCDDGTQRYEYKFHVPLPSLESADGAAGGSAHSKIMTPMPGKIIKVLVKNGDSIKADQPLLIMEAMKMEHVIRATKDGKVEEVFCDVGDFVGDGHVLIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSX5</accession>
    <name>A0A8K1CSX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSX5"/>
    <dbReference type="OrthoDB" id="73653at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016286">
        <property type="term" value="F:small conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015449">
        <property type="entry name" value="K_chnl_Ca-activ_SK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10153">
        <property type="entry name" value="SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03530">
        <property type="entry name" value="SK_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="2">
        <location>
            <begin position="244"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="50864" checksum="20CB539A8BC5B366" modified="2022-08-03" version="1">MPKDVERQALDDKCAQRPAQFTFVQDLRHLYRRRRQYELLACGCGLLGVLLMLAENEVVISFDGENGTKDAVLRGMKWTTLVSTVLLDGMILMQYSASTAILKMQNAVPATTNFIPRNYGKIILELLLCSFHIPPGINGQVEIRQFHSSLLISGAQSCPLQGRIRLTQDGNYCYLVYNYPVEAFGVFMLVRLYLFGRYIRSSSSLYSQWVAFIGSLNDINAMKPFFHFKALFKLRPLYLLVPLTLLNMFLAAAVIRILEQPVQAVFANYWKSVWLTAVTISATGFGDYYPVTYLGRAFTTVSAMFGGVLLVALIQSLFFGIADLSHKEEKVKYLVELNAWERATQENSAHLILAAWRWYKHKAQRDQKLLHAVYHYMRAARRLRDEKPTIELTLEEQITELERVVVAQMRRMDQEQGRILKRIQEKTRRVGELKAQLEARKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTE0</accession>
    <name>A0A8K1CTE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTE0"/>
    <dbReference type="OrthoDB" id="10249562at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="4">
        <location>
            <begin position="86"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="239" mass="27125" checksum="19A0130CEE82D3E3" modified="2022-08-03" version="1">MALWQRHDATVVVVIPDADEALWTALEGGTYGAAVSEYDQGARKRVLSLCEAYYAIVIEELLPMPVHATPATLWEEFCTILPSFPRFFVVYHHFRRLGWLVRPGLNYGAQFVLYRGNADTYHSEYIVYVQTEASSASWHVVQALTRLAEDVKKTVLMCQVHETNDGQRSANEHSAVDEPTLQLCAVYTFNGRMFVVDAVPIRFWDTATVDQDRVSYAFESQPMILKSRSKKKPKAKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTQ5</accession>
    <name>A0A8K1CTQ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTQ5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053329">
        <property type="entry name" value="Merozoite_Surface_Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39110:SF5">
        <property type="entry name" value="GLYCINE-RICH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39110">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463642" evidence="2">
        <location>
            <begin position="28"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="605" mass="49320" checksum="0A0FD20BE8B0CEEF" modified="2022-08-03" version="1">MVQIKSMISLCLAAVALTTANLPSVQAEQKTFSDSFTSADGKTSGSVSVSLRGAGSLSGSVSGDISGDVAVGIGAAGSAAVGADVGVDVGAGANVDGKIGAGVGIGAGVGVGADVDGKIGAGVGVDGKIDADVGVGANVDGKIGAGVGLGAGVGVGVGGKVGVDGKIGAGVSLGAGVGVDGKVGIGGKLGAGVDVGANLGGKIGAGVGIGAGVGAGVGVGVGAGAGVGAGAGVGVGAGVGVGAGAGVGVGAGAGVGAGVGAGVGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGAGVGVGAGVGAGAGVGAGAGVGVGAGAGVGAGAGIGAGAGVGAGAGVGVGAGAGIGAGAGVGAGAGIGAGAGVGAGVGAGVGVGAGAGVGAGAGVGVGAGVGVGAGVGAGAGVGVGVGVGAGAGVGAGAGVGVGAGVGVGAGAGVGVGAGAGVGAGVGAGVGVGAGAGVGVGAGVGAGAGVGVGAGVGAGVGAGVGAGVGAGVGVGVGVDAGVGVGVDANVGAEVGAEAGAGADGNAGGNTGGEHDGEHDDEIKPPTTSPGNGDNNDGNDNGSQEPSAPEPTPEPAPTAPTDSDDSSDASHDTPIQGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUL0</accession>
    <name>A0A8K1CUL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUL0"/>
    <dbReference type="OrthoDB" id="162462at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="19867" checksum="86C411528B78FC2A" modified="2022-08-03" version="1">MTSPTLQQRWERFLSEDAGTLAFSTVLLSGFVFAKELHGPHLPESTSFAHRAQRAMLAAMPKVPMVVASSAVGIIGMNMMISAVMDARRDYTRSSVKIALPLFAALMHAPRGPRSMAKSAVGYGAFIFGADYVFEKMHRREALLMETPPHHHHDHVFAHHGYFPEPVVHNDHGAPLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUN3</accession>
    <name>A0A8K1CUN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swt1-like HEPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041650">
        <property type="entry name" value="HEPN_Swt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18731">
        <property type="entry name" value="HEPN_Swt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swt1-like HEPN" evidence="2">
        <location>
            <begin position="50"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1532"/>
            <end position="1549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1949" mass="218128" checksum="53FA41D292D58687" modified="2022-08-03" version="1">MDATEAHVAAGCLHAVMSLAHVHLVPFVQQVRREYLQSHRKGGGYYDDTKYEELHMQDLAEQLKFIRNHWKTHFGRSYRKELRSSVYGAIDIRNKLAHQQEVSTDWCRNGIAVFNRLLCQINAPTSALDQVREIVSTMAPGKPKPTKEEKEKMRAVKRAQEGEAALQKAKEYAQSSDFANAVHWTTQAIERTDLTATLATLYALRASYRYQLLNYEDARQDAEQAISCDGLNMEGYRWLSASLMKLKRKKEALSTCLSGLQRRPAYDKLQERLKHLLRADVPVNAAPVDQSAHQTARAKRLQCEEDATIAASKRRVSDAIELMDRALELVTPEDFVSDVASIFVRRAELHFIARAYGKVIEDTSVALKLQDGVLPKASALQCEVFVACTREDAARAVFARAYALSAQAPELVALRGTFLDTTTRTSATPDVETAERAYETAVSHKSRQETATAIEWATKSVLLDLRRALPSSKLCASHLLRAQCHYELGQYTQAISDVERVLGWGESQDEASVLYCESLVRLENWSRAQKMIDSSHPNPSSPNADKLRYWKQLVGAKLGLTVPWRVLAFSTYCMWTREECFEHAKWLGSVGEYLDAIALSSRALDRVRGDEVELRSTIYQHRAFYWLSMKDFQHALEDIDKAVTRTLFIFDSKTAKVYDVRSRALMGLNRAQEGVNELISGLNAYPGDPDLKKYQVELEKRGCVVIAKTWTGGKKFVARLGSNSPCFDDQNPDDMKLTRVECSERATRYVEINELEAAVSWCTRALMLISATDPPDTRSWLHLTRAEYYLKWRKYSHACDDAEKALQLRGNQFAEAYRVRHEASVALRHQEEEALRARERDDALKETTATSTDRECKGDEPAVNAVCEPPQNKQNVSQRPTESAPEPAPTEETFTQRQCAEEAKQAAARGEMVEAIKWTTRSLKFVKPKDPAAVVASVYVRRAEYSVALKAFADALVDTEHALTLRGGRYAKASAVQCQALLGQGEKKGAHKVYVDALERSPASADLLALMHLFPGVNVPQSTPPSASPGKKHDDPNTDQSMSNSNVTIEQRECLDIATIETCIERAVIVMSQVQVFKAIGLIDRALELVTSEDSPSEVALVYIRRAELCFIAREYQKVIDDTNQALDLQGGLLPKASALQCEALVACGRPSEARLVLNIALKLSPSAPELLLLRTLFDDIYLLNRNAPGDDYIEQLYQTAVGHKSREKLDTAIEWATRCIEANLRHLIPAEKLFDSYLLRAQCHFKLGQYMQAISDVERMFGCGASRGEAWVLYCESLARLENWPLTLVMVDRGVEELINRLYASLHDSSVKSPDPSDYQALLVIRRQMEAMGMVEPADALSKKNEDELDDHEDIEYVSESESVVREPSREELNVERISTESVVSQQTKSIDAEETFTQRQCAQEATKAAANGEMAEAIKWVTRSLAFAKPKDPPPLVASIYVRRAEYSVAFKAYADALEDADRALQLRGGRYAKASAVRCQALLGQGKKKLARKEFAEALERSSTSSDLLALVHLFPGVKAPPTIASPSHKSEKTVLPKPQTHESRSTAKPPITKASFKEQAIELISRRNVGNAIPWLNRAVALDGDDLELFVLLAQCRFGLHQYPNALKDVQFVVSQDATNADGHFWMSKILLAVRRYDEALLACIRGSSIAPKHVGLQELRQELKEKLEHVARPSSNQSLADTAASRLSGQDPNGLMELLTVAIAVKRTSGPSTVVSTLYYYRAACFFAGNHFNEALEDADEAINAQDGGYADGYVIKCRVLAKLERNEEALGVCSAALVAIPDSMELQQLRNDILELREQAKEMNAPQRKKERKRLTQEGAQCMSQGDFSAAEDRFSKAIVLLLDGLCYMPTGTSRKASTLYSHRARCRLAREEYELALEDATQAVKYHPSFPEYHRLECSSLMGLQRWEDALAACDRGLQYDPEHKVLQGLRLEIASRPRNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVI2</accession>
    <name>A0A8K1CVI2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVI2"/>
    <dbReference type="OrthoDB" id="162063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42307" checksum="5D72DFE597B454F8" modified="2022-08-03" version="1">MGGQSSKSEAKRTQHHTQTHSSGRRQRTDKRQTAGASSRKQPEHASRYQTQRPSPSPASSYSHEYYTTSTDTSENVYSGQPRTMDQNYAQDSGAARRSYIRKLSSASSGSIVSDVDDRFRQASLRSAQDRRLIEAEKILEEIAKEYAAKRAAGLVPTKPVPARTLLWEEMAKNSQTKTAKRGQCIFGRDTPHMCGCTSYKKKKIPGQENPGGICEGCNHGGPWHRLTGGSMMRSSRFTRSTVGSSIAHRTRGSSVLKSEARSASYEYDSDEDDEDEDEDDDEDIANEVARPYDFQSPVPRPLPPPPAILLSDRSSFLSSTSSFGFPSRLSSGTNSLGALLKAIQRYRQMGLAEDEIEARIRADFPPVPRQSSMVNSDASVTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB38</accession>
    <name>A0A8K1FB38_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB38"/>
    <dbReference type="OrthoDB" id="162866at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="29767" checksum="572E70C6DACAB272" modified="2022-08-03" version="1">MANLFSSKGEELRFLRDRIHVLEETITTHAVKTFVVTALELYLSIMLVLSLFECIDPDERDEQELQYMTQVAWVPMPFAIGLVFGHKVAPRFAPAPENLDRNLRITKIITWIYSLAFLIWDKDMTLKQGPALQVAVLFIVCDLARFEMEAARLIDDDEDEEEEELEQLANAASIAETATAEEEAFKNELQAIANQRPSASPAIMEAPTPTPTPSLPLQGVPESTYQQYNDYPPPGSQYESGFNDYGNQYDDYPRQSGHGQRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBW7</accession>
    <name>A0A8K1FBW7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin delta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Delta-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_006546</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as a positive regulator of hedgehog signaling and regulates ciliary function.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBW7"/>
    <dbReference type="OrthoDB" id="2588702at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02189">
        <property type="entry name" value="delta_zeta_tubulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002967">
        <property type="entry name" value="Delta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01224">
        <property type="entry name" value="DELTATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="9 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="57"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="58096" checksum="214DEDA94BB74ED0" modified="2022-08-03" version="1">MSIFVHVGQCGNQVGDAFWRLTESVYEAPATSTASLSAKQAAASRARRKETPPTLYREQLYHPQSGKARCILVDTEPKVIRSMLEARQHKATGSGSVFVPAHVHFEQSGRGNNWAMGYNLQTHRHNVLPSKSDASSMVPLTGTHKTKRVVIESRSAKQELLEMVMESLQKEIEGLDCYQGVVLMHSLGGGTGSGLGCRVLETIRDTYPRSYLTTVSIAPSCASGDTPLQNYNALFTLGHLQEYADCVIYKENDDLLRTASYWKTLRDQSQSNASPGREMGEEGLTKAKKTSLQELNALAAADVAGYLFPIVASTSAGSRSIQMAKPFDAGKLVSSCCPLPSAKFVDIRTGIVCDRQATQRKPSVGSVDPLFHTVIGRTNDTLDAAARRLLQQTTQSFPRSSTMLPCLATSAMVRGFAGSDLTEKGTQALSQQLASAFPRAAWTRISSEGITYSSYSPFGPYSGKASVSICVNNGHVRSSVRHFLDRGRRQFQAKAYVHWYTQHGLEEADFERAFDQGTKIVQEYDALLPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBZ6</accession>
    <name>A0A8K1FBZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBZ6"/>
    <dbReference type="OrthoDB" id="74661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="156" mass="17442" checksum="E3DE467A44020D43" modified="2022-08-03" version="1">MVIEVKQTLRQGAVGQVVSELVALDLLTDYAVMALLTDLNSNWEFYWISESDDSRIRIHTTTVTQPGEAFQVIRTLLEQTPDEGVDITLPFLNVPVKRRKLAQTLPSIVEGREGGGIREAIERYYDIASILGPDIDMARAVANQVVRSIPAFSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD78</accession>
    <name>A0A8K1FD78_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD78"/>
    <dbReference type="OrthoDB" id="998115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152:SF1">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="197" mass="21971" checksum="EADCFA73E4F46ED3" modified="2022-08-03" version="1">MCFLCSADPVEEDPRKTNVNKFSVSMMDAPRTDPICCLGSCVCPCCAQIYIRRKALHYDMTNYRCCQGYMDGFVPCLKSGECGESSCPNMCLCLEAFLCNGCAVSSTRLLVMDRHRLQPDEWDNRIIRCNNCLQVVSIVCDLLAICVSGAQDCAQMLHCVAQCTYASTQGCMTAQVNVELDERSRTEAPSYQDMERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDC4</accession>
    <name>A0A8K1FDC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010309</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDC4"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="301"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="901"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="964"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="908"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="964"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="980"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="995"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1028" mass="115974" checksum="2984354F71691DAB" modified="2022-08-03" version="1">MERLCDDLVQEFDDACAVFTSTLLSDADPGAQLTMIMDVVRGGDELLPNDVMERVESEFLPQIVQLLLSRAVVENACGDVTQVNSFFQFVLERVALRLLQCDPCLLPSLVRIFDEHRPFYLYHLGDQDEVITDASEYTATKIQQNKSITTSQFVASTRVGLASILFLRNIVCWGELGGFTLFLRCLQAGSDAVQHEENSAEGEEVETSSDVDFAFEAMQCIFRALYCVKDHLSSQFLVRYFPMLIDSTRIYISRLPPSELHGVPREALLEVIQVMEAFLPHLPADVRTQVDEYPEVLDDEAQTSETYQTKALDEARLHQLFMIPAFRDGMLSLECGNSPAASAPWREELMQLQKLFVSLAETELKAVDPTEFALSHHDLDGQPTDLHVQMDADEFFCLLLDRVETFIRALEPMSPSSLLPRATTFLDGCFGGVLVNQILTEQGHMSEREEKFFALSVEVAKKDHLTESLELYVQGETLDGENAYYCDHAQRKVSAIKRVCIKTLPRTLVCHLKRFEFDFDTMEKVKINDYLEFPTELDMYPYTSDAFAAASGEATDNIESHTRMYDLVGVVVHSGTADMGHYYSFIRDRNTEGAWFEFNDQSMFYDREDVELVDVSSGAVFPITHSMIINGVTYLGSFLKDCVIAEKPVQGKLPYSDDSRVESASVIQIQDILLNEVRFLDRFLFSLRSEAAASGKVDDGSAFSSHAGGVSSQTSRVRSCTFIIERQILMALSSHLPESACPVDTNLISNQAQLKNLFIYQFDQVMTPVLVSYVTTAPRIQRDKLVTQLIAVLEDVKMSFLDQMLAVFRALLCADAAVPSLRIHEQLFSPSSGILEAAAYYRDHKTLHEYAFLLVEFVILQAGDSCTLQRYLQTEDEIIRQVAWIKDWLGNYLDPHETVRSANTHTHNSGDDGARDQGNDDDEDVMLTKEFRRLFALAERAFGFDFFPKQVDRNMAPEEDLAEFSVESLEDSDATSADENQADEDAHDEVDEVYQQEHGRFNTKERVPECDDVGNRQSRPVVHTSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDK2</accession>
    <name>A0A8K1FDK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ectoine synthase</fullName>
            <ecNumber evidence="3">4.2.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N-acetyldiaminobutyrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010564</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-4-acetamido-2-aminobutanoate = L-ectoine + H2O</text>
            <dbReference type="Rhea" id="RHEA:17281"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58515"/>
            <dbReference type="ChEBI" id="CHEBI:58929"/>
            <dbReference type="EC" id="4.2.1.108"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ectoine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.108" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDK2"/>
    <dbReference type="OrthoDB" id="10266423at2759"/>
    <dbReference type="UniPathway" id="UPA00067">
        <property type="reaction ID" value="UER00123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033990">
        <property type="term" value="F:ectoine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019491">
        <property type="term" value="P:ectoine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010462">
        <property type="entry name" value="Ectoine_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39289">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39289:SF1">
        <property type="entry name" value="L-ECTOINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06339">
        <property type="entry name" value="Ectoine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="198" mass="21774" checksum="9670EE5592B610A4" modified="2022-08-03" version="1">MLQHLGRAVAKASVATRTRGLHGTSARAFLFRAPTDVPAIATENGAVESRRYVVRNDGLGFSMQHEVLRKDTPVRLEFRNHVYAVLVTKGSGSLQLFDSHGNAISRHHHELTEGSCFALSASEQIEITAKTDELHVVSVMNPPLAGDEQRNPDTGVFPVIDHDGIERESFDHSQIRRLCEPPESLKGGSSPMKDDPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDM8</accession>
    <name>A0A8K1FDM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDM8"/>
    <dbReference type="OrthoDB" id="342064at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031053">
        <property type="term" value="P:primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="588"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="617"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="718" mass="80007" checksum="2E3F64CB3946FD8C" modified="2022-08-03" version="1">MDGPGNYPPFREDYPPPMDYNRGPPPPGGPGMYPPPGPGGYAPHPRSPLLGEPDFRGRHRSDSRGGDPGYDGGRHYGGGGHWGNRSRSRSPPGGRFHRGGGGGGGGFRGGPPPGPAYGGDWQQGLEDHGANGANNGRVERKAVQSIEPMDSYKVFMMRQDENSTPETYQQRYEEYKKKYTQRLMRAFFDDHKREEWLQERYSPAIRFRLDQQKRSKKVAEAKLFVERIASGTAKINLDEEHDLTGKDYDNDLEDSKRILYVRRIPCACPVATLSEAIKKAGGNFQHIYLSDPVKKSAFDFDRSAYIIYETPEAAAEALPKIHNTFVQDADLFPPFRLQVSQHRSRAPLKTPSYLSVPERISADYNQALKLTVLLDNALYTKASDLASLGIEALLEKDEVASAYSTEKQKLDVVVAYLRRVHHYIYYAGVQCIDMGDIMHAHPALFCRPPPTSKDLEEEQARKESVGTQEESSESKTIGGWAASLDEKVQAYIEELSPEKIAEKLEKEKALVEEIETREESSLESTYSNYAEKAGDDGKHRCRLCTKLFKALDFVKKHIRNKHPELAVDKIAEVGESYMWEQYREDANRPLPPIETTNTLTNPVLGGRGNNGSPFQGRGQGRGPYGGGPPGGNRGYYRDGPGYRGGGGYGPPRDSRARRGSFGDRGRSPPRRAPEGDLPVDPRQVTKSYQDLDNLQDTKVELSFDALDSLPPPKKKSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEB0</accession>
    <name>A0A8K1FEB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEB0"/>
    <dbReference type="OrthoDB" id="3360032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35465">
        <property type="entry name" value="CAVEOLIN-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35465:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20913" checksum="184380EE2088C739" modified="2022-08-03" version="1">MPCGTTQVYHVHNLDSHKVYDVKISYPASIPTIFTIDAQQLLVNGENEPKSTRRRLNTAKLRLLPSELLRKWHATASKETQARYRLETLDSQSFVVEIAVRADVEGVSPTLDLSKRQCVYNIVVEEMLFAAFPHDTLILIAWLLFLLFVTARFVYPYVYRKISLELDEDKKITNELRTKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEM9</accession>
    <name>A0A8K1FEM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEM9"/>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF1">
        <property type="entry name" value="DNA OXIDATIVE DEMETHYLASE ALKBH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="190"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR632852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="32996" checksum="03C06B10DAA0AC3B" modified="2022-08-03" version="1">MKREREETTAMAATADAPDVGDETIRAAAQGAASVTPKKAKTQPELREEFSSARIDANARDSAVCISVSMDVEKLFRGARVIPLTSDGASWIYYVPKWYRRIYAQCMEDLQITLPYADWFQQVWNLHPKDHDTIKMFGRDVLTPRYQQVYGTSYRFSGKMFHAKEFPEQLIHAVTLMQALVVHADSGETYLQGALVNWYEHGDHYVGPHSDDESHLHLNSPVFALTLGATRRFIFTPRANTPDQSAKKLELSLDDGDLLVMGGTTQKTHKHALPKMKKCAGKRISLTMRCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FET5</accession>
    <name>A0A8K1FET5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FET5"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="1">
        <location>
            <begin position="246"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="667" mass="74146" checksum="F78D1369F84151C3" modified="2022-08-03" version="1">MGAACCRCQQVAFEDDVLRFTSSAAVSLNASQLVSVVAAHSSTRRQRRRGNNPRTTASAMTQSLANYVSFPFPFAAKMKARRKARKPKTDDKADGRYGKGKGVLKHMVKVGGLGEHWQKNEDGTMSPLSLVDCCVRHICGQLVYDPTRLRSLSTSERNLALSSDAASVILEWLKCHNALSKEHFRDLARYLFQEWNLPGLVNVNSSWFDDMPVLPLQHIKSVNLSRCHNLETLGSDRWLHVDELPSLSTASFQGCTNLHKSVPDALQGSTRLTSLDLSGCRNIDDRSLIALRRLFRLKELSLAGCIQITDEGLKCLTGLCKLEKLVLSRCPKLSDDAFDCVEVAFPHLKQLDIAYCRVTDVAIAHIAHLTSLTRLVVRGCRQVTDIGLERLSSLTKLTYFDARHCDEVHSIRAEWTKMEILLLTRTAFAEADAAVLKHMEHMIELDVRSCRVLKRGFEFVSLLSKLKRLSMAETALGDAGLLKICKSVRGLVVLDISHTEITDSGTEGLCFLEDLEVLHMDTNGITNRAIANVSTLKKLRRLDLFGASITDNGLLHLTAMRSLEELEICSGSITDRGVDLISRIKTLRSLNLSQNRNINVKGLLSLQALSDLQHLNLSDTSISAISLRHLHPLKELESLSIYGCELSSTHVAMLQDALPKLRFLRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFT2</accession>
    <name>A0A8K1FFT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFT2"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="50"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="781" mass="86409" checksum="8532A1B284995912" modified="2022-08-03" version="1">MLTTHWRRSLLFLRRAVRLQAPQWPSAVRAEAMRMSQTRDFATGDAESMAKIRNIGILAHIDAGKTTTTERMLFYSGAITRMGEVHDGDATMDFMPQERERGITIGSAAISFDWRDHQVNLIDTPGHVDFTVEVERSVRVLDGAVAVLDGVAGVEAQTETVWEQADRYQVPRLVFINKLDREGASFERACESLESRFNVKTLRVQLPLGEEAEFEGVIDLVGMKMLKWLDKDGKQIQQLPIVNTSGGKMAELYAKAAEARQELIERASDHDDELGELFLMEEEIDEETLRAALRRIAVRRETSSSAIITLCGSALKNKGVQPLLDAVVDYLPSPLDLSPFEAHVIKKSPKQKGKDAETATEAITRRASPEDPLCALAFKVKHDRQRGLVVFFRVYSGVLQSKAQLFNTTRDAKERITRLMLVNADDADEVTEISAGNIGAAVGLKNTFTGDTIVAAKDHNGDAVILPGVQVPKPVFTCSVEAESSAKQKDLDDALYYLQREDPSFVVSVDEETGQTLMSGMGELHLEIIRERLRTEYKLEPTIGAMRVAYLESALDRVEKTFVYDTMLGTDRQFAQIQFTLEPLLHSEDNVSGEAAINNVVEWQHAPEKKLPHAFVLAIEEGFKAAFSRGVLSSNRLAYLKVVVDEASCQYDQDSNANAFRACAAMGLKDALKEASPVLLEPMMKLEAHAPDRCVGDVLSDLTSQRRAHIQEVGAPVDAEGSGRQGRSIVHAHVPLAHMVGYATLLRSKTQGEGSFSISFLKYVEVDATTQERLLGPARPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHV6</accession>
    <name>A0A8K1FHV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHV6"/>
    <dbReference type="OrthoDB" id="164487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="50560" checksum="C626476A6D043B63" modified="2022-08-03" version="1">MKLRLPPNALPPLKLTPNEKRWLADEASAVVAETRRIEEQFFADNGTLERREWKNVKSRSDFMVFKERRPRRPGNSSGLTSTRSNFTSSSSMGSSTDSFDLDSNHEGSVSSMSNEDDSIVALMKDPKLPMIIATGEIDGLLEDCVYGSYGGDEFAWRQRTAYLKDKFADSKILARVKVPTHEDPFQQVIVKWFTQEMPALMGSFVQHRDFVVVEANGCVTEVNGTTFGYYLVHSVKLPGVNDLSELNILRSKTSFCFITRQTAPTKVHVFVRGFADPRGEMSETVAVAVAVESISSFMNTIEGANSKKLTWLMERKHQARLMQENRTYTSLPKTRECQSCGKTPNWLTGAALSMCQVCVKVICSKCTNHRRLLVSVSKEGVPNEVPLAFCFQCLLDAKNLPARKVALAETGLLHRTPAAPAAAPPPPVVKQASSKPTSSKPASSKDSEPAKPGIILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI54</accession>
    <name>A0A8K1FI54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI54"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="2">
        <location>
            <begin position="190"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="40912" checksum="88323F16622DFC49" modified="2022-08-03" version="1">MHPAKRRRLEMPQGPHDFQPRQNESSRPVSQLPTLSSLLQAQRTQGSSPSVHALRVPLETMAEITPITLRRVKTDESIASSSSSTSSTSSSPERRVPKTSRYLREMDRRTILQRIKNGEKQSVLAKEYHVSRAAICNLNKHRDLVLSRSDENPMAKHPKKPRFKAKPIPVEPPKATSTVYELDSRPVVVLRSRLQQQETSDRDFRRYTERLMRLVLEETLALASMRRDNSDAEYPPCVITLSDQAESSIMTEGFRAIEPLRPVGTIQFKDSSEMDVSIPPGLAQHSVLLLAPTAFSGERLCHAIKYILTRPGASQQRLSVVTLGMTQQALALIRAKYPGVSIVTAQVGNVDLLQSRLQQVLPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIA5</accession>
    <name>A0A8K1FIA5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIA5"/>
    <dbReference type="OrthoDB" id="123540at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29698" checksum="9F629C2C8E7C68C3" modified="2022-08-03" version="1">MEEANCPDELKRMLQHSRPLFAWYCLEYLERNACPRPMTLDYLDGMVTHVATEITSVKSRSELGQFDLLLCASLTLTSTRPTLIDTHFAQLDDEDPLSLSIDAKDNLYVDNVPWKCRCVFPSADRDVLLHLSLTTGRGSQTLKSPLHKMMEVPANREGMYWPDVDAKTDDGMALEPLVSAAMVLASHKGGLGGVAFPAFLGGFLYQLGVTRTDEPMELPGTAGVVVPFLSAPNVEWPLWLLEDWQSLGTLLATSIGQIAKTALTSGLNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIA6</accession>
    <name>A0A8K1FIA6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004617</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIA6"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="31849" checksum="E8FDE7338596421A" modified="2022-08-03" version="1">MVVATVIGIFIAKSYTTPPGGISRSHNPLFRLFTHIHASLFTMNEWVQSIALVATVPILIGAIIEISNMDETFRMGMYHIIVLFTVVGMQSFIIVPVLYCVVVRENPFVWVWQMLAPIGYGMVFSRQFLPLGHATKAALRTKKISPALFGNVFPLLSMMQRSTLTIGYPTAVMAVAAYSGCHIGMSPTVYLKIVGLTFSLSFGGTMLAFHEMAVFLMMWHSFCSNEDVPPVAVVLAGLGIVNFRVTSMFSVMVNSMLVRMISHVCERGSFQIPHDSGHETSEEQIARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIA9</accession>
    <name>A0A8K1FIA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIA9"/>
    <dbReference type="OrthoDB" id="164305at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="66925" checksum="0EF3072DC063469F" modified="2022-08-03" version="1">MLMYAPPNFADVNVTKRSLDAIINSPSNSPFMSPSSSPLMSWTTEESEAMTSSPSSDEDFFVTPSAGCAGREDWEALLGDLDMQPFALTSSGLTHGLEEGSRRYYEPNGNDALAPLDPFSMPTEAELLASTTACSTSSPTDPPPLLTTAGTLEPAETAIRASKLAVILPSTAKPSVPLTPVASPPDKIMTEAESEVAKIQRRRSQIATSVQRHREKKRQHRESLKQEFVELSAYLKLLQRQCKQRHTDEERVVARGEEEVTEERRKRHHSEALNQSLKKALFEQTSFLMGMRSITSNMPAPREMHIHDWLHSYTVLSAGDEAARRKEYLSYFNDCKMDMALKLILRETDGLVPRLSLANPSFAQVRIVYDGTDCGYDVEEMFVPRELRQEEAFVVPGTGQLVKKLTSVFLFQEHSGFTFDKFFEATVNATKQVGIYWPSSGWMPEALDVLDLEDSSRMSYSNFHGSMTIHDDRVVPSGEDVAVETRMLSRTKKWEDEAVIAWDYADRDEMYPITGDRSIRRDMCGAVVIRREGNGLISYRSVSIKIFAPTDLQATIDDNDRALIQRRIYLQSGELEAAKNKCLLSVYHSLAASSAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKA0</accession>
    <name>A0A8K1FKA0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKA0"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00374">
        <property type="entry name" value="RNase_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475674" evidence="3">
        <location>
            <begin position="21"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="239" mass="26627" checksum="DEB6B5E3EC2C09C8" modified="2022-08-03" version="1">MKSTLAPLASFLLAVGSVSAEAPQRLRRSLASGDFDFYLLAQSWQPEFCYNKESQYPGCKNPDEWMKTHFTLHGLWPEYTNGEYPQNCNADSFDAKTVENAVGMDDLVKYWPEVEYATSSSKYPSFWEHEWTRHGSCTGLDQATFFSSVVSLLRDGTAQTPSFIQNNVGKTVSTADVRKAYGTNNVVLICTSSKYLSQVYTCWAKDSNNIPTKQMACPSSVLKEDTCKGSSVVIQSFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM47</accession>
    <name>A0A8K1FM47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-adaptin appendage C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM47"/>
    <dbReference type="OrthoDB" id="5072at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="2">
        <location>
            <begin position="84"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="186" mass="21682" checksum="3EB2CA8C9257E221" modified="2022-08-03" version="1">MEEYLRSKQSILKKIRRRLMIIGMTIVLLAFIAFTLGAIVSTEHKRVTKFQRKTINLSLANLYFVYGGGATALSFHGFYLDGHWRKMQEDGNRLVMHLRLNHPLRQDVESHLLTNGFHVVAVEAKETVLQVYFSAQHFGTGSYFLCEFVFIYSRRFFQATFKCQAREEASEFVTRFNLQELLTVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FME2</accession>
    <name>A0A8K1FME2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FME2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="35946" checksum="EEFA423E37B56294" modified="2022-08-03" version="1">MTTSVSALRQRYASLDANEHKPSAGSFDTGARFSVSELRRRFERPTTAPEPVRIEPSRVVVMKKIAAMEASTPRAVATPATPEPVLSIIEKSETSSVEETVEVSEKTIEVETIAEDVPEVPTVEEPSNESPVETEAEPSNESALEQAPLLAIPAAAAVVVPPQEATPKVEAKRVTNDSKIKPPTVWRKPQGSKPTPVEVTKPIQNRVRSYSASKAMSRAVHPMPETRARSSSAGTIPMSQLQPRSAPRASSPSHARSPTMSSRSPKSPSSRLPEDLSALWQKNAREMRERLLKVQGKALKFEMHASYRARLAESQTRRAKMSSTIVNACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMM5</accession>
    <name>A0A8K1FMM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002749</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMM5"/>
    <dbReference type="OrthoDB" id="60484at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="82"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="420" mass="46626" checksum="0D5DB46FD06A7E60" modified="2022-08-03" version="1">MEKFSRLLPVDDGWKQLGGDQRPEEAFFPTEIRNPEEHPVAVQTAAPTLSSGYQPTGSSLPHFQSFLNFTATSNMAQQLDNYVIQRRLAPALFGDVLLCQHRASGQTVAVKRILLSAAAERRTISSKKRVRENVALERELYHNFRAVGGHRNVMALRDEIEAEGYLYMIFDYCSRGELYELVSGSESGKLDAATTRKYVTEIARGVQFMHSNGYAHRDLSLENVLVTEDDVCKVCDFGLVAPANQMSSETVGKMFYMAPEVLAGVSYDPKKADVWSLGVMLFIMLVGAPPVESAALTDARFKIINAKGIRYLINRWGLSETLPAEAIDLMEGMLDVDPRRRIGMDQVISHPFLYTANAALTLLEEDLKVCSVTAPPTPTSSNMASAKENRFASRLQRFFRRSSKRRVMAVSACQPAAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMQ2</accession>
    <name>A0A8K1FMQ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Molybdopterin converting factor subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMQ2"/>
    <dbReference type="OrthoDB" id="5531344at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000010">
        <property type="entry name" value="Molybdopterin synthase sulfur carrier subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01682">
        <property type="entry name" value="moaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10100" checksum="C3EFBD3706389FC8" modified="2022-08-03" version="1">MGIITTHPVDLMKLRVLFFASVREAVGKREETLELQDEVCTLATVRRALCARYPEAATTIQAITLAKNLEYADDATPVQDGDEVALIPPISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP29</accession>
    <name>A0A8K1FP29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP29"/>
    <dbReference type="OrthoDB" id="160734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="622" mass="68468" checksum="674B6277687F33AA" modified="2022-08-03" version="1">MASVASASGSGSAETVKLPHAIVVGPNATRNATVLGGSCSHYAPGPDGCAQPRTCADCLLKEGCMINQYGECVSQSDKCFNSSIDFHEGLDLNLVFPEAAANNADTQQYWQFPSLNATYCDSSDSVCRKCRDANFWLASYRSDSRYCVGESGCICIASCEINWSWNNFPKCPNDDSDSDDAHPGQSSSMKVVTYVMIGSLGVFVFCWLTVWYTGRKYRAELERRDALQEQRLRERQEAREQARTSVTSGLQRLSLDGWNRFRRELVEKEHSHLAGADAESSTASGPVATNALRIPSRRRQRATCIGRVMASHEGSSGDAELTRTTITPQDVATNITFTGGTCAHYPPVYGQCAKSRVCSDCLLKEGCTINPYGQCVTADVTTSDWSMDFRRAQERGLVFPAAKNTYIEQRWYFPAFSATYCASSDPVCQLCRQENFWISSVYGYDSRYCIGANGCICISACDSVMWQYNNGEDCSYLMGDGQIVMSDGNAALKMRMFSMLGFLGALVIAFGVYTVVRRRHQIELARLAEQREARRQALQAQREQSRATAVLGLQSLSLSGWAQHRRELIDKEQTRLASGGERSTTLEAATAYVSIEDANDDVIVAAVERSGPQSTPGAREPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP65</accession>
    <name>A0A8K1FP65_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP65"/>
    <dbReference type="OrthoDB" id="69053at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="61"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="85100" checksum="E25988794DCAB002" modified="2022-08-03" version="1">MKLVDDEDNTLHEEEGPKDASESANEGVADTSAGSEPIGSTGAFGLRWPKPQELYQLTLPGILEIVTHNVLAVVPAERSLIYMFDKSTNLLSLQVTSNDDEDAADQEEEESDRSFPPVMGMISACFLQRRCLRMQEPHAHRSLHRDYDVPRDMTLHSLVVAPIILHHRAVGVIQLLNRFDPQDGDAASLSSPPPLLNKNTGRLLDDDEVHLRRTKPAQQQRNRVGFTAKDEQRLIQFASHVAQLLDHKLKQLSPAEADEAAKHLEDRAKNAMELLNMMNEKLEMQATVIPELKMRPRRRSTSKEPIVQAPLARPPPRIVEPPELEVDMLKVIVGISRAQALFRGHHLRKIYRLSELLQQHRAQKRQERSVLVIQKSTRNFFAQCKRTKRRSAIQTIKKAFNAYKLRAKVAEGIHLKRGILNKLPRRRESALPVPSASVPSQPAPPRRVTVTERQRIKSASDIQRHFRGHKVRKQIRKALGFSNISKAIRNIVLLQSFIRGGIARKRVQKMLKEKRERRVPNMVCMRIASNNNETPVIPQAPSYPLPLRTPRHQRNPTVDNCTTACISRLELPLPPRNETRRRHPQRKLRLSDGKSIANNQEDASSGLTMDSRRLVASPLRGTTARTAPNTLALLDRDGNLSHSDAVRAFPTVMFDTSCFRRKKHPPAVQYVESWMLRKQPIPPVEELRSPSSPPKLPSLLPRLSAPSQTAWKDSELLCCFVPAHPGRQPVTPRRLSIHRSSSIRIRPQTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPC0</accession>
    <name>A0A8K1FPC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPC0"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001881">
        <property type="term" value="P:receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045188">
        <property type="entry name" value="Boi1/Boi2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902:SF27">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902">
        <property type="entry name" value="SESQUIPEDALIAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="147"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="64414" checksum="3FB00687ABD4A21C" modified="2022-08-03" version="1">MNPLLSTGEAPASATNQVMQKISSGSESSAPVSEQVRVPEVAPSASPSAEPADSPGVSEDIAASANATNDYGSDKRAVASGSSESTVVVEEEPREESITRSHTANEEADVLTALPLSISMLSFSSLQSGADGTASVTDPKGDDACAAPDKTGWLKKKDGWNSWQTRYFELKSNRLYYFASESEGIPRGAIVLDHVHVLRGKGEHSMTFTITASNKSQHLEIIKFSSRMTHQIHPRKSCVLRVVQETEDNVSGWVTALNRASFYCNLSTNTSASGSGSVTSQSQSQSSSSPGRKKKTPFYRLRSPSSSASSVADDDNRQSSGTIDSASYHHFGSVKYLQETDPLLWEIHPHDQQKIRKKAAKARTRSDYVAIFTKYSSTFRQIFLPRPRPITIEQTLRDILPELFLINNVLYGGGDENNSLENIFEVLDGCIKKFASAQEERVRAVSSLLQACARTISGGDSYFVVHSLLGNPSMIIRPAEARGHPIEIEVSATNPHQICITVFSVFSFHHIEDVENYGDGEPGGSAAMPEPLLRIHTYHVQEFDFASGKSSRWLRIRADGVKEDNEGQRTSWVSKRNGSETGFGALLDALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPN6</accession>
    <name>A0A8K1FPN6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPN6"/>
    <dbReference type="OrthoDB" id="165525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="72"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="449" mass="49659" checksum="3E1F57593A9E1F00" modified="2022-08-03" version="1">MVSVEKTTTTASVAPHGPSWADGFMDILAKYERNSERQLYVYGISASRCPICRHRVKTDGTACEKCGQTVSKKSEKCTRCAKSKPELWCYECDKYFCEVCHKKPHTLMLGGEPQLQHNCYPIDGSSGKLFRHGSWSSNLLAMTKDARKQQVKRANDLKSKGPRSVKSEPASVAPSGPSVQSAPAPSIQPAAPFFGAAAAALSEASSHSVQHEPVQQSTAPAPAVDYGIYNSLFERVELPPAPVVDLTATSPSGSTAIEDPLKVAVIEEYDRCNEYTLKIEAKITSLNAAVRKASLQDVNMAAKINEHIIGYRQTLERAIEMRYRALAKVVLFSPDVRTQARSFEQQQLGDVPHVLTACHNKSAQIAIALHQMQKHLVDLRHRIDRAIASGDPTQLMQLQTLGNQITETEQQIRQAKKDRDSQFVLMVQFSRRLRETVQREANASVKPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPV6</accession>
    <name>A0A8K1FPV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxypeptidase</fullName>
            <ecNumber evidence="2">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPV6"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF201">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488395" description="Carboxypeptidase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="62812" checksum="3098182E61163ED8" modified="2022-08-03" version="1">MNLRTALQLALVAALAAFSTASASHSKELRNEHQVRELPGLKKAKDLAFDHFAGQLQLDSKEKLFYWYSESQKDPSKDPIVLWLNGGPGCSSVSGLFTENGPFVALQDGSVKINDYSWNRKANVVWVESPAGVGFSEPQQPAEYYNDDVVADRLHQFLGKFFAKYPELQGRDFYITGESYAGIYIPYLVNLLVERPIEGVSLKGFAIGNPLTDNEIDGNAYFDYYYSHALISRQQYHSALEACTNEIAQCMFTPVNCTEKCEQAVAAGYAAAAHDKFNPYFIYGDVCQLSNGQAGALHEKHKKNHPTPTTHRGDIGPCADTFTETYLNTKELQEAVHLETPIVWQDCNPFISRHFTRSLSSLPKYRNILNRGLKAMIYSGDADSVVNFIGTERWITDDGLKLREVKAWEAWFGPDKQVAGYVQEFEGLTFKTIKGAGHMVPAVRPLHGLHMFECFLYGEDACKKFKYPFDAFEEETGEEDSNEDEPESADIQVTLQTMQRAVVGANVVFHKQSSSPTVFVVSALVLAGCFAVVQLFQTQTRFRRHRYRGNEHIPLNSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTN8</accession>
    <name>A0A8K1FTN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TKL protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTN8"/>
    <dbReference type="OrthoDB" id="669224at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04371">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="361"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="9">
        <location>
            <begin position="718"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW69778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="901" mass="100883" checksum="D97993E446663F57" modified="2022-08-03" version="1">MQLLRTGSGSTDAIPIAPSSFQLPRLPVPPIFDPPLFSPLIAGLFNSSALPGAANMTEAEIRQTQMAIAKEIVHSARSLASGLVIMNMLGALLKFIMGVFLLVRIRRYRILAFQGDIEAANKIILPAFEPLLWFFCAAAVPFFVWSAATVNQDEYTIYVPKIVIEVVLAWTNLLLLLVLVFMLQSSLSTRALLQSMVVTFVLSTYVIPVVWLMENYGDKAHQEAYFYIHMGTRLALLLFVGKVFIYPPARASVRTLQEYCVFVAIYLVLRYVSYEMLHQGYVQQSKTLQWLTTAVSLLCPVFIWRLLQADTEHWRGIGKRAVELQAAFRRNGGRVDEQVSSHGLHELIEMHRKFIIDFARLELHEVIGTGDNAAVFSGFLYPKIPVAVKIYMPPTFTEETVAVFSHEAALCGALRHPNILKFYGLCVYPPNICLVTELCQGSLYELLHARANRPSDETYHHRQQLLIDLGYMLDAARAVAYLHSFSLPFVHRDIQPAKFLVSVDGTVKLTDFGASRTLALRTDGGGDQRQPASEGTGRTNATQPADLTTALIDVPDISSINTMATTPEYTAPEVIRAYHAGTVTYGEAPEVFALAITMWDVLHPGIPKYPDQPIHLLNRQHTPEQPPSVHSIIDRVVSGERPLFEADVPESLHDLIEGMWQADPRLRPPMTNVVTTLEIILEEAGWFFAQELMADLAKSTPNTQTQTHVHGLLPTDAQTSFTGIQAVEKLRMRDYVETQSEAVRLGNLLMDAGFLHHVKHEQNFEYSCSQYYFDEDHIQLCQPLAMIEDDETAATVRLLQREKRRRAQPSAGPNTLEHPRVCIDSISNASQVMLGQNTIGFTCPCRQLGQRLEPKQATRRRFRPRFKVFAENTSASRPLMDDRSVGFTALDDAGPRASRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Y5</accession>
    <name>A0A8K1C1Y5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Y5"/>
    <dbReference type="OrthoDB" id="10558653at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441213" evidence="2">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="87" mass="9242" checksum="7BD99891B1E63D94" modified="2022-08-03" version="1">MLKRVLLIAAVVCATVSASPFKQDPYTRSDGTVIDNSNPDAVKEPASTGERSIYTPLSNSGPMAGVGRPPQQGRALKGIRSRKEPTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3C5</accession>
    <name>A0A8K1C3C5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3C5"/>
    <dbReference type="OrthoDB" id="167246at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="197" mass="22479" checksum="4E1B7070FB2545A9" modified="2022-08-03" version="1">MQDPQTGAWRYFLFVQRTMQDELDRHQLHASKPSDKSIPKFFFTTLERPSSTNGGHVYGIRRSYGDFKRLYAAIVAVTGESALPRFPTDTLFAYFTGETQSNLLKKRVALESLLQAIESHPVASDTAAYQEFLANTETYEQYSEAPVSPVFKANSSRSFSETEYQLPAHRRVSQFVLSSHPEEMARHPRRHSIQGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3D7</accession>
    <name>A0A8K1C3D7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010631</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3D7"/>
    <dbReference type="OrthoDB" id="16290at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00006">
        <property type="entry name" value="16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265:SF0">
        <property type="entry name" value="12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="S-ADENOSYL-METHYLTRANSFERASE MRAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="405" mass="45890" checksum="9C9DE874520DE32B" modified="2022-08-03" version="1">MMPPQIMGGGRVATATLRLQRRTVGGSDVRYFFSWISDSSEKTKAPEATPAPTHIPVLLNETVSLWVNPSTSEAKPQRFFVDGTAGFGGHSKELLLRNPEAQLLCVDRDPEILAIAKANLRDFHSRVVFHNGSYAQLDPSLLQSVGFPDQVDGICVDLGANSFHFDEPRRGFSHMRDGPLDMRYNQQDRGNLTAADVVNTFSEVQLTKIFREFGEERLAKEYAKAIVRDREERGVVFANTSDLRECIERIARKWNADGKRGKKRGGHSVSVHPATKCFQALRIYVNDELQHVATGVEQLVTQLAPQGRLATIAFHSLEDRPIKLLFRRLDTMARRAEDEEYEDYFDEDFDEDDEGEDTSAQTILQRLGSRRFRLVKRKAIKAKAEEIAENPRSRSARLRCIERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3S9</accession>
    <name>A0A8K1C3S9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008557</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5752at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041670">
        <property type="entry name" value="Znf-CCHC_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15288">
        <property type="entry name" value="zf-CCHC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="1393"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="179"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1101"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1249"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1324"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1101"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1143"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1249"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1493" mass="165744" checksum="5F0673557A9F19EC" modified="2022-08-03" version="1">MPTTAEGGEMAAPSLPLLSDKQGRIVDFARIYRRSTDDEAFESLQDLAEELESVSTLFKEREKQAAANGTGAPRYAYAPDQLQLLTTTRDGGNLDTATSKAMMGKRGERTEQNKGKPMRRFLPTSSNPPFVSAGSARQQRRVNDDAFPDELYLKVQQVRWEDDIQWGIDFKREKKEETAFVEETEDGEVRSSSSVGNSSSVNSQRRPSTGASSQTKTGTSSGKQAAVPRTYKEMYPRHKMSTVDTPWVPSATKDDFDMSKPRHYRWELEDDKTTKSGSAQKKTDTNTTGAARQLPCPINRDLDDGSWVGAIGWKSTKDMPDSKLILDDNDVSLIFTNPEMEDVRPTLRIPERKLGATELKARELQQKEAEKGIRTGTVITKLGIPSEGATTNLVNGGGTTSKTKDSRIIQGVGSVHHSLPAIKLSMTKPELPKTKLREFHRPRSKFKINERMMFAQPPVVPIPVTEESAVVTQIKKSSDLNPIAGGKLILVEYTEQNPPMLSNPGMASRILHYWRPPEQKDDSVLGKKAKKTRPKPPEMEMGQVITLGDHDDSPFVGDVPPGRMVTSLNSKLFKVPIFRHKPLAPFAPTPGSRQSGNHELFLLCRAVSKGKKGSIGSDGAKTKLYVFELPDLYLAGQVEPQMEVPAPNSKTANRFISPYMSFHILRLFKKASDGERLKMEDIARAFPNQSSTAIRKRMQEVATFERGGSDSGWWKKKPSSLLPSEEDIRANIPPESVCLYESMMSGHRRLLDIGLTKLFTPTGVNGVINVLIKRLESRKQALSASMIEPLGLTSVAKEKAEKELWKTDSTIRKLETDIQVARYILEQLQLTPWNLTNNYVECHLQGKGSGMLQLGGIGDPTGRGEGFSFVRVPQSRAKKKDGEEEGAAGVNGAEAVQKAVAAVTGTTADLRKLTMKETGNVLRNLGVPEADIKNLRRWDRIHVIRQLSTMATAIGRGGALSKFARGARKSLSAQQQEYRRKCDVIYERQMDVLGDSRGEFSSEEDDDVEDDMDLDELEEAVLGAGAFTGGSREKMAKLGPRNLFAKGGGGLNRSAEALAEREDADELERFMAEMKESSGSASAGRRPDIDSNKLRNQLRASGISEGSAQSSQGTLPGSVAAASRAGSNVPSAMATPTEHRSRASSPTSAMRSISGNTPSGRIRGKKVLKRTVRVVEEDGTERVRIEFVVDDKQVARFMAKQHRQERQLHADERNQLRKRKRMLALDDESSSQLDKAKKRKQLQEELKQLQKTEEQNKGYQEMLEKQGENSLTGTPQKGVIRCTQCGQPGHMRTNRSCPLYMADESRSKGDESSKVKVRKGSDQVEKITLNLAELREGARKHQAEKKRKRMQEVKEQAELYKRPYMNATVKQSRSRMPVSHLNSNLNLVVEKLLGMPESELFRTPVDAALVKDYYQVIKQPMDLGTIKKKTDETQYDSMRDFIKDLELMVNNSKVYNGDPTRSLITSNAVMLLKRAQEELATLNADGGMATPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W3</accession>
    <name>A0A8K1C3W3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3W3"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001319">
        <property type="entry name" value="Gastrulation defective protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000019">
        <property type="entry name" value="Nuclear inhibitor of protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="43"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="342"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="621"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="690"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="740" mass="81242" checksum="6906C0DEA44B91FB" modified="2022-08-03" version="1">MAPAFRPPSWAATPARSRRSTKLEVVKDGVVIEELPIGRQACYLLGRNEDVCDYPLDHPSISRQHAVIVHNRDGDVTVMDLDSAQGSFVNGKEIEPNKPRVLKEGDRIEFGASTRKYMVRNLEDKHVEAKHDGKLDEAAMEELPTAFGGQKESNTSAVDDQKSLDPVEARKKREAEIAAMTAEMMAAPVLVRRDESEDNEGGANEEEQGVDEEEEDDDEEEDAKDDVASRYNIPMSHEVKLSSHTKSITCIAVDPPGGRIATGSMDYHAKLWDFAGMARHIRPFRDLEPDEGHAVVALSYSPSGDRFVVATGSSQPKIITREGLEEMQFAKGDMYVVEMANTNGHTHTVTGAAWHPSLRDQVISSSLDGTVRIWNLGGKQSLGKLVNATVLKAKSKRGKRCAVTTCRYNFDGSLVACGTMDGQIQCFDPRKAYAGPAITIREAHAEGGGDLGISCVRFSPDGKHFASRACSDDTVKLWDVRKTQKPLKVFQGIEGVVGTCNVAFSATGTSLVAGTCVRKGQQLAGQVRFLDVHTPGLLAPIAAVDMQEDESAICVEWHHGLNQVFVGSSNATCRVLYDPLKSTKGVLLSATKKLKVQSADFGVRVDGVGEIYNPNSLPMYREDMTRKRKSTTARPDAKRSKAPEKPLTGPGAGGRISGSATFTQYFMSNHIKGSSFREEDPREAILKYAKQAEQDPQFTARAYANSQPSQKMDKRYQLAERTLEEERIAQEEEQKRLLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C493</accession>
    <name>A0A8K1C493_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C493"/>
    <dbReference type="OrthoDB" id="105255at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="652" mass="70091" checksum="4456DBB84B8B12A0" modified="2022-08-03" version="1">MTVQCWKIKSNSDGSKSIVSSFTNDKCPVQLDIPVLSGKFHAGEKIPIFWNVDRLGGDNIDNEMDMPLPVSKIDETYVRTCESVAKCDPTLGASVQTKPQSGSFNDKGDTVTFSSSNELEFTTSGDFPVSAQAHVYDSTDGSISYYFAAYTTLTVQSNSTAGGTGQQLGVVNCRMSRMDALNETLDASTSVQTSDNCEIAVKLNPLSVVKPNGKLDVSWRATMARGDDKDIHLPTPLTSATVDGQSYQVVSSAVKLCKSDANCNEFTAASDLSVFAKGSPASFNDGSANLVVKDVKVPTKGWDTAFLHFVLAGPSRRYDFTYYFQLVASDSDIAGEVEKATYNKDDGTNYCWEVLADGGEANVTANSVATAGKGDDCPYVLGFSMPDSEIEADASIALEFTVAERSAFSRAKFPSIDLSTVYDGATQEDVNVPIVDIYACPDGSVCTPFSANKTLIYSAPARSLSDGKTTVSGKDIKFPGEGKFTVMVHAVLPNTADRIDMMALGSITVGNADGKESSGGGSNTTLIVVIVVVVVLVLVLGFAWYKRRQRQRMDKLNPVMFGAPPIARSTNHNLPTASRGSMSSEPSGSFGYHRAERSPAEGGHSLERHHDSLSYDPYQRQSFMNMSVDESNLSFAFSDDHRPSIESEAYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4H7</accession>
    <name>A0A8K1C4H7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4H7"/>
    <dbReference type="OrthoDB" id="200110at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38019">
        <property type="entry name" value="KDA ANTIGEN P200, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38019:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="594"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="654"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="742" mass="90011" checksum="1A04D646F4CAD594" modified="2022-08-03" version="1">MLRAKSRENGSPIAPGDRGDNDPLDIEVLSLENFDEENAKKPILTSPRSLEACRMLGIEPEELLKRPLEYFVARASRDEEPALIAKRAARYEVNRQIQLKNARMQREELIDAELRGVHAGMSLRTRSFCHSPLAAKLSIGRPSESMTLQAQQHESTVIEREKRELERIRQRQALEMQQLLNFELKMNELHRERELKEQEQRRQEERMMKEKLRRQRQADEERRRKELAKAEEQRLEVERTRREAQERQQEMVRKAEQEEKERERRRRDLQRHDQERMRREEEQRLQNELIQLRMQRGAEQKAHEMERREAKRQQVLEQKKRQKAQEVAEKQQRNRMRIVGVLEDRELMRRMQLEEQERKQQESQERRQRFEDERRQREEEIRLQGMKRKEMIEAVQQQLRLLEQQKRERLLEQEQEVERRLQIQEVEKQLARKEQQREERRQEEERRRVYTRMEQQLKQRQDATLSKAEQKNTIARMVQDQKKHFVRSRLQEAKLREEEIQAALLRKQKQDKYREEMLLSRIQSDNERTRLLKKQRDDLLRRRQQIKLAAMRQKQELVESFYRMKVTKKYELPKHLQASLIDRPHSTSYLLNRSVTSQEAPEESSRQRPRQLKRPASAAPRSSQWASSTSPRSARPHTSRQANSADLEDDDRTLDVQNVDSDEEDAELEELRRKQNQELLEVLQQEHHAEEQREYLLKQVCDPTERKRMEQIFEKERAQASERIMRLTQEHEAALATRLQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4I5</accession>
    <name>A0A8K1C4I5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4I5"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="43"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="511"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="951"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="958"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1012" mass="114504" checksum="78D41F89E713C9EF" modified="2022-08-03" version="1">MDVRWAELKAEAKALAKDIGQSGRDHHSLAKPGPLLDAVRAQGIPAEHREWVWPILLHAHKQNLQRQSSSLATYNQLLEGVAEDKPEQHERSGLKQAHEMAMERFSHLNPFQERKIKRILLAYIKSKDGFYYCHGMVEICAVLSTFLSEEDAFWAFRLLLEVLLPKYHEESITDFQIDCLVLQELLERQDPALAEHLAVTGVTIQVLCTKWFFSFFAESMPFDLVCRLYDILLIDICCRRLSSKIIFSTAAAVFLYLSQMLQEMSDPSVIVEVMCEFCWSTLSDYSVAETFIDLVLFLHDRMLDEEIRGMRLKFKEQLEQEERARNPSKSISASPPKKNEKSRTLRSGKSQSIKLIIQWQKVDDDATVNAEQLQREEAKKIDARRTKRSPTLSTTEEDDSEVQLEIVATPTEKEVLAKVYQGIDKINRRRSRTSSLRNVQLLGDANTGLGSSPYPSRPLSLSGSVLSVVSSPRDQEELERASTLSDDEDASWEMLQQRGDPRPVVRRSLRGVPDEHRSWVWPVLLAQATEPKNFPRVFPYEDDADFDGLEQEVTKAIENDISRTRNLKESQYAPMRRVLKAFALRNRRVGYCQGMNELLAVFLQYLNEREALLGLSLLIETVLPSYHVDSMIGLHTDCAVMDTLLRQNDPELHAHLHTMGLNMEILCTKWLVTCFLTSLPPFCGLQVIDMLLARVREKRAGSRVLLGVGMSIFFTLRDSLLAAKDAGEILLAINEYFAQEMTKTRVEMESFLSFCHHVIDQLRPEIVDQFRLVHRDEVMERFAKFEAKKIEMRQQMDQVRARQQKGDSVPPSPTKSDTSANTSSSASGSAPTSSSSGTTVRHRKSFLSSYISMPLLGSSRGGSAAASNDDNPRDMYYQRVDVAVANRAFVDDLAKMDEQLEDLAELFVRGKIDEKEHACIKAQIVRKWCRGLNSPQSAMLRVQRVKAAFGDPNGIMESGNSSTGGSSPVHGSQSGNDDMGGPRTRKKSTVSLYGRMKKVKKSAIAIFKSTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4P8</accession>
    <name>A0A8K1C4P8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4P8"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433506" description="Protein kinase domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="462"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="738" mass="80932" checksum="065122BB56F114FA" modified="2022-08-03" version="1">MKMRAAMLTLVLCLGLATCQVSVADGVDFQPPRPPPDYDGDSSGAMFNPFISDMERMVEDKDALLVVMDESSMPPPPPGAPPGPPPIVCDGQPAIMTRSSQFAGNNGCFPPDVVTNLSCSCLIGFNETNEWVFRLQEPTQDQVGPPHKELPGSDVLGVTAVLLMGIPATVTSFKIVADTEKPLPLDILVPPGPPGHSDGSSNPVLVRAPFKNALDSVEVANVDFARLPIKPGFLPSSVRSLSLRNCQITRISSDFLNDFQELTSLDISQNQLSGIFQDVTPTTCTNSHCTLKALNLSHNAITSFPSYLLYLNSLETLDLTTNSISNVTVDNATFDALTQLKVFRMDTVTNGSDCASGTFKTVQNAILCVPTGSSSEDPEPAPTEPDDSSPLLIYIIIGGSLVIAALLFILLKKRPWRKSEDKDILNSYFESTVGYDDTTATVSATLLNDPIIVTHRIPYKDVRVANCISKGGFGLVYSGVYNRRRVAVKKIRPDRAGDIKQIELFLREICMMATLSHPRIVEFIGVSWDSLRNICAITEYMDRGDLREVLHGFKLRNQQLTWESHKTIIAMHIAEALTYLHSLNPKVIHRDLKSKNVLLDSDLNAKLSDFGISRERHFEETHMTAGIGTSFWIAPEVLVGKDYDERADIFSFGVVLSEIDTDDYPYWNSENIGNKGQENAILHMVANGSMRPTFSESCPAAILSLADQCLQVDPDDRPSAAEIVYALQEAMLDYHCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y7</accession>
    <name>A0A8K1C4Y7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair and recombination protein RAD54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y7"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18004">
        <property type="entry name" value="DEXHc_RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000021">
        <property type="entry name" value="DNA repair and recombination protein RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.850:FF:000021">
        <property type="entry name" value="Protein CHROMATIN REMODELING 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="205"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="564"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="763"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="865"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="978"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="768"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="890"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="916"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="932"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1040"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1113" mass="124460" checksum="45B1533CB0D75DEF" modified="2022-08-03" version="1">MSLLRRRVPSGGAHGGGSAPFKPFVLPLKKKPAEDENENRRKTSTADNRQMLETGEAMTIKRLPILSFFTVPTEEREVKLRQPFKSPCEGNRTGESRRLLQVKTLGMRRRWSGNVMKPLVKHDLPPVTLEDVDDDPLAGMEKQHPNVTEEVAKTPPAVENAPPPLVLWQDEENPALQVIVPEIVGKFLRPHQREGVQFMFDCVAQIRGFDGQGCILADDMGLGKTLQSITLMYTLLKCSMTIDRTPMIRRAIVVCPTSLVKNWDDEIIKWLHGRVKTIALFEANRDTVIKGIRQFVEGSKPTCSGLQAANAAQVLIISYETFRMHAQRFADAPSCCDLLICDEAHRLKNANSQINRALSSLACRKRVLLSGTPMQNDLEEFYAMVDFTNPNILGSTSEFRKEYLNPILVGREPDSTDRDREKAQSCSAMLCEIVNQFILRRGNILNAKHLPPKLMQVVCCPLSPLQDELYTHFLESSAFRNMMKKESANVLSSITALKKLCNHPLLIFDESGKSNTKLAGFEGCAKFFEAAKLGDNIGGSGSSSMRRAGGGRTCHPEWSGKMLLLDRLMQQMRKRTSDRIVIVSNYTQTLDVVSSLCHERRLPFVRLDGTTSAKKRKKLVDTFNDPTTNSFAFLLSSKAGGCGLNLIGANRLVLFDPDWNPATDKQAAARVWREGQKKMCYVYRFLATGTLEEKIFQRQLSKEGLQNIVDDKEEVNSLSSKDLKRLFILRRDTLSDTHDQLKCERCQWRNPGEECDHEIIEVDQDGTDDSKGSSDGELPPEKHYHPQIGMPPEEDLNSWGHHRAYDSVDDEVMQHAIADLREALVSFAFSCRVDWQLLQDYHMGNEAEESEREEERKRKRLEKIAAAKQRNEDANTRATTKPKKKKHVDSEEESGQSDSDEDDFASSSDDSEDEKENVPDFSHVDDDHAGETEEEVVVNSESDSEVEVFEPPPRQMASTLSLIAPVIENSPVKRALPTADAAAVTEPSQKKPRILKAINNDSDESDWEDAIFSKPPSPPAPATQRPSYASSVIIDEDSKESEPPGHEAESSEAVGYATGAPDSSEHPSPTGMNRCYLADRHGFFLGEGLPQRLGLVGDNTVNSAIFRALEDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6A0</accession>
    <name>A0A8K1C6A0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6A0"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="5">
        <location>
            <begin position="82"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="914" mass="101455" checksum="A56AFF3B85BA9424" modified="2022-08-03" version="1">MEAIVKELRKDEETTLTTLRVFVAVCVAQLSVFLASDCNVSAIASEVVAKDSAGSNGATDAARQRAQSFSLYDGGSNSERFIQRIDDVVQRIDRVITEHISEHHTALLEHVGSVDGLQGQVASIQGSVHVVKQVVHDLEATVRAQHDRLARDIQKHRNVEKCGELVRRLLRFQQLAERVLGSSVGDGKANGSGDAAARQNAELVTVAVAIREIESLTADLHFEDLSVVRRALPNIRRTSNAIRRDVRNHLKTGVQRLSQADVGEALQILFYLGSLTETVQTTVNGVIQEVERKCGAVIAEERLVTRNAANGTEVTVQKADIWRAIQEVFECVRVHALQVWNLQRVLAKMIDPSTGRNFLDMVIEKDEPTLFATFWEVSCAIVRELFSATLSYRSSVKTILIASYPRMREEGNRVLAELHAATAQRTDLLNENTTTSQHQNALHAIAGSAAERNQLLDAMTPLADAFIERCYRRIASPIELMFPQSANFHTSPPSRSDMQTLARTIFAEMELVGHDAVLIERVSQQIHKAVHLFCTTSKKILNTGKAAVALMPTYGRTANQAHNIALLSALYQLDDMITQLEARLGSTARGNAQTSTKLVPSSTQLQKQIKALQEKEFAPCHEQIQELQYTILGPYLQALAGVLESIFAKMHDESFADQTTSRDARGANAPIPATNPTGGSRYMSEFSSVFNVIIEEHIRRMPSVPCVTTSVSAFIARLMSVFIRHAALVRPLEENGKLRLANDMAQLELRLESVLPLRSLGAPYDELRAFRHLIFLESHSILRDSMVDKIRPSNVWHHLISRAPLELQLPHHMKRWSAARYVEWLDKTACTETMPSSAPVSFSPKTLPLGYPCLVHPKLSILAEKEAWKEVSKCLEAYVQRVGANPDAEISALYEILQESNAILLAGYELVSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C750</accession>
    <name>A0A8K1C750_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C750"/>
    <dbReference type="OrthoDB" id="4693074at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34494">
        <property type="entry name" value="PROTEIN CBG25024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34494:SF1">
        <property type="entry name" value="PROTEIN CBG25024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="32687" checksum="304C491C8D500C90" modified="2022-08-03" version="1">MWDDISTIGGAIATAATAVAAGVTFGQVEALNDSVVKCANFTAKNAEQSLTRHVGETVGAGDATAATAVAAGVTFGQVDALNDAVVACAEATAKSGAIVGKEALTLVDGITDSVPVVGHVKGGVMYALGENERGDRAMKGASRTVGVVAGGVGGFVVGGPVGAVVGGVSGGAAMDGLTTGVDSAVHGEFRPNGQIACWAEVAKGEDAGQVARGVIGGILTPVMDGLGGYSAGRGFAKIQPARNAVVAEEANQPSSVLGPRNLIRPPRATPKRKTDKSEDDCEPLNPALDQAKDEDEDAADPSTNNAVLSPEHSELLTMEARAASLTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C778</accession>
    <name>A0A8K1C778_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C778"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="417"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="698" mass="77099" checksum="2678424BF01D3B8E" modified="2022-08-03" version="1">MTAVMAASPMVMDHCSVSDMTLTGACTNSSNPKQTEPVACVGYATTSCPSNPTAVPLQHDMLNVSDLGITRVVDVDAFYVDCHKLYMSGNQLTELSLYSKPLASLEVLDIAYNQIASFSSLHIPTHALSILNVSGNPLQRINLSESFSKLHELIAANASLSLLQTKDAGELLSVTASYNNFTSISKISCGNSLRYLDVAHNLISDWQSFNPPTGLHELHASWNGALNFTRGDWSQLDKLTVIDFSYNLVSNLTGFIFPSSLTQLNLYANPIARIDIRQSDFAILEAVELVVDETAPLFKIPCDSPHAERKYLTSKIPVCVFEDSIFQEMVDGSEQVPSSSPPPPLADYHSETSNTGLHVGVIVCVVVVVAIITYAFFWFRRRRLQGDNKARSAIDSEITETLQHPRFLTVRVDPDDVSVIKDLGRTSSFVIAAVSVGERQLWMKRVQRKLTFYKPQIASQLLDEIRIHSSLEHSKIVQFLGVSGASMVDLTMYCELMPNGNLAALLAGMRRTPGDWGWFGGPSSNLYGLPSKLDLAIDVVEALVYLQSYDPPVVHGDISPRNVLFSENWAAKLTGFRTNRDVNTAIVSQCDTMVRMAPEILRGEGAWSVEADMYTFGMLLIELDMGESPTNSFSGMRSRNKLASEILKRGFHPTLHPECPVEIQSLVQSCLRADPAQRPTSLMIHYDLSQLHRAKQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7L4</accession>
    <name>A0A8K1C7L4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7L4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16681" checksum="4E79D0BB958A7463" modified="2022-08-03" version="1">MRIVRVEGLPNVRRLGVQSPYCKWRLVGSDQREVASSRTMPGIKGGVSPQWETQSFWIVLSGCGGVSALNGLTLYFVVKTAGMLPKTSITIAEGSYRLHDVFKSDVGTDGKWEDMNLGLTAKEVHAGVLHFKMQHRHEQQLPPRKKLIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C853</accession>
    <name>A0A8K1C853_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C853"/>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="155"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="627"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1056"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1062"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1081"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1099"/>
            <end position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1120" mass="129279" checksum="67FFD2605C909F7F" modified="2022-08-03" version="1">MAEVLYRSAATPSKQLIDVYESLYGRLRGARPRNWAYGAYEELFLLRLAFLHAQMAQNRSIAYLKRAIQLMDELLALRKLRLLQRKTTVKRIQWPHMLRLPAKFSIEDLLFLRGFFWEMLEDARGTQSNARRKSWRDYDALHQSLSTVVLTEQKRQYEAKASVESRSKRMTGLHVFIGDTLDLAISDILHSKPSVNIQCEGKTITTKEPPTWTNLAPSWREFIDIDVHSTKARVLIYVKNRSRRRMDGDQILGYVQVFMDDLLQSNHYEKPQYYDLICDDTSETRPRIRLAFQIMMRREQEVATRRSSKRWHGLWNLADLQENLNGDLRMFVRTRWVWSSFGRLWSEDKDYFVAGWLYHRALSAWNDGSVLEDEYPVYADDLIGLATSYRATMGSAWRASGQPLLERALELLQLAYAASGATSMVLWKKITYVSELLSDSLASEPLKHELSKTVPASSTWIKMYGTNGNASDVYYFNQDTGMRFDGILSQHAVTKPLEYESTEVTVTRRAPQPRRVVVMKTEMRHRVQYYCEEQRRLHEADPFAWIAVFNPRRDEMQYFSQSSPDTPSLRGSEVPSTYAMIADEFLMYHVLIVQEAYRKFRVVRRHQRLFRGVVRFVSWATKEWLAARLRLMIRAEEKRKRSLNCIHVVIQRATGLRAMDLLTSDPFVSLELVDATKTIVARGKTSIRKTTLNPRWHEEFQLEYAYSTHEKQYLLPQQLAVDASDSVAAPMLRLIVSDYDVITLPKTEIPVDALDKEGTAANARKAEKHDFLGLAIVPIAPLVDGKSLTADLKLRDEDGYDSPRSRGVLTISIEWMHMEEERFSEYRRNAITPNLLVKPRKKSRPKPYWDALGALKDDWTVSQDAYHLVVSGCTEVATPLDQLLRLHRRWKQANAIGKTAEEAKLLEQRLEATMKKQYHTKFTALLHHASQTHVTFDRFYQVMLPLAQDYAESFEYDISEAHELTLKAAVEVFSRATQAIHQDQPIDPEVPENYPVALFVQVAERILKLRLAIFSWNKAYSDIAAFFEDAPSWVLSPADNQLIQQLDKLAVMLPESDEVTSDQEQGRPTTPSAMAVKPVATISTIPTQETPTGKSAVAKRLERLEKERKKQERGKGTRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C982</accession>
    <name>A0A8K1C982_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cilia- and flagella-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010067</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CFAP45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C982"/>
    <dbReference type="OrthoDB" id="1902038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033253">
        <property type="entry name" value="CFAP45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15504">
        <property type="entry name" value="NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="10">
        <location>
            <begin position="241"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="331"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="70583" checksum="4454AFF83CBD5B90" modified="2022-08-03" version="1">MPAENASSNGEAWLLIWRLWASPWSESARDVCEDQIHAAFSAFRFILLPKQRQQVTLSSKLPTTMRAASATSRGSVTTGSQGSSTSRRYRRIAHSPQVDDTLFGSSKNAKPLTKSDRTRQAGRDIVGGGASNNQEEPSTQPVKRHGHRAPSPKRPTVVVGDSDLHRIKNETKIYTAVELEELQARRDAELEQMRLTSKARKEHMLKLSEEAALRAPKSQIEQILDTEKQEVIRKAKILKDQAHDSVKLIRTLGARAQAFTIRDQQKKMKEELDDEHHVYDEKMNMLMEVERLEGLKRQEEIDEAKKAKRYADRKVLEGQISDRRREREKESELVAQEAAEMLAKIKKQQEEEAEKERLKAERAQLTMDEIKKFNEISLNRKMDEKRKQKEEEDKVLAYQLKKAEEQRQLEEEEARKRHEAELRCAKLRSMQEKMANEKAELDELRAKRAAEARERQAREAEVALLRKHKQEMEELRRARGDQALHRQRARIKEAVMQQQEYESIMAQVENDKQRVKENEEKKKLSSYEHRRVLQQQIEEKEKLKKDVFVKKQIEGQELKEEFTRELEKLEQLRLQEVEELVKAGVNPLYLSEMKAVDIERIRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9J7</accession>
    <name>A0A8K1C9J7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9J7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="655" mass="73868" checksum="E7CD60E8BF1D7F6E" modified="2022-08-03" version="1">MAPVLSLGRSRWSLSGAIRVAPVVPAPAGHMMITKRAHQKVNPGPSAIATVFPGEEKSIPCLFTVQESRELPKVIASVSVKSIILPTGWLEPFNAWVHRYRLLFSTIGFISSVLVGPAPLVSPQLGVILALISCVPMIFIQMLTFLGLRYDMLRLVIRSYEFWYLSIVNTVCCVLLAMYYQDVRAILGIATIGGFQCVLLIDANFRAIKHMTTLSLVGAMAALSLALGITTGTLQEVHDFPVLCHRNVTLMAGDVIAHGFVTSAVLLLRNAYYKRRYTRFAERHDSLRANISDITVVRCVGYQCRLTWRAVSIAFPRLSQTCAPKRSTLGRRASAVLRLRSVGTLYIIRAQDVFFPVWSVEKASLPQKLRAGLRVSGFIGFLSTGFAFIQAITPHNSRVTSLNQQQSQLTVATLSIMFTSIFVLVFVLTLYERTIFIRICHSFDFLFLSTQVVMGHVCLALMCEWDFRGLSIISSCLWLHWVITLDALPPLRREQLGFPVRKWAKVVTMAGLILVCFVNVDLVVWNSQQFVNHSMLRFSVRGRVIEWRVMSFLLNRSVSIFVWLIRLLFRQMVYKVDDLVMLSGAVEYEDTMLHRRRVRMATKERLQRMAPKIRALSALDAIRKQRTTLTTLAHIPEISRREVSPPTSPRGHRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9S8</accession>
    <name>A0A8K1C9S8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9S8"/>
    <dbReference type="OrthoDB" id="164633at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="48549" checksum="67D677A7DAA28F8E" modified="2022-08-03" version="1">MPPRVAQAPEQSPDESDASLFQDHDSDASLFLEFDLTENGEPNHDGASTKTGTSKRSRRTIKVKMTAEEKKRRNRECMRRLRHRRTILVTEMKGEIRALEQQLDAAVEMSSKRDLTKDSESKSEANQADSPVSDAEARLKKLIRQLREENYWLQKQVARKDEASTRVTELLKAREQVCYPIDFAAFDDAELAAWICNTSHFFPMLPASQVFNIVMESYYVLQENLRIVQTRAENEFPVLGWRDRRWVDNTWANFSLQKTFHRVSTHELVHKTWQILSEFEHISVLQPKAQHMKVLQRLNEHTLVIARHSRLQPHGESFCAIYLLFLMEVSDGFIIGTRSFDADVEKMHPFMCEHMFYGQLFYCFHFRYTTSGGCHLTFSGRVDNAQPHTAQYCITDILLAMLRWESHCVGPVCQIEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9U9</accession>
    <name>A0A8K1C9U9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9U9"/>
    <dbReference type="OrthoDB" id="91894at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="175" mass="19547" checksum="60F015DC3D8B3E39" modified="2022-08-03" version="1">MASTLALNFRSYRPEDHAAVIEIIIAGVNMYCPEDEEGAAGNREYIKWSLETDLADIQGTYFDSNGHFWVLTNTNEGREEIIGTVALEGNEDGRCELRRLAVKPEYHRRGLARKLVAHLEDWARSHGFKTVELSTGVVMAPACTLYSVLGYTETGRRAASNDPSYVMVSFEKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAF0</accession>
    <name>A0A8K1CAF0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAF0"/>
    <dbReference type="OrthoDB" id="168385at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="905"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="938"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="947" mass="103648" checksum="E0FB99BC0072B6A6" modified="2022-08-03" version="1">MASVSAQLKWLTRLKDEEEESSSDSEASDSSVSSDGRDEALAAKRRATAATGRETAAVVKRTSSASKKTGEDESDEAMRAEQLVYVRSERLQVAAAMKASKEVGNGVLAEGDGGKKRGKAEKPAPEKKRKRPTAAEKKKKDEAVRRVSLEQAEAVEDEPASAEKPRRRPREAKVEVSVVKTAEDAVVANGDAHVDEEKKHRKTAKSRRRASEDTAAATKAVEATNGKVQHPHLDEEKKPKKTEKPRRRPSEDASVVRAVDVANGNAEPSRVEDVKKLKKVERKKASRGDVEPATKTKEMVSKKVLAKRKNLISDSSEGESDGEANGERVRKQSTEEAEVAPRKRLKRPLPSKAVKIEDPAESSANVKKEVVVKRPGTKTKINKIESKPARDALNGHPMKKLKRPIEKQVASLDDFLKEEEVKKSKKCSLKSSENGDAKENDDFKPEKGEDVLDGPTSAEASPLPTNDVTQPDPKFVQVAGVDPESAVVEGVAGTSSAQKNENGPDDVRSSGTIPTTSVAVNRRVEALRKVSVAEESEEGAVSEDESATQETKPQKYDAEVAETNGSGKPVDPTSFIIPKKRGGEKQITSSSQPTASLHDRRGAPQLNGVKPGPMLAPSPSPAPDGGYDVSFPDPAQQHRKPRTKNPVPPSMPPLTQSERDFMRLAKKANSIFKACSLTASGIGASGVKPHLVSAFGSTTQRYGVLDSSGSLYQEQTTMMKCVTRKAMKKAQHPPSFYGQLMEPPPCAKPSGDAEQTAEVQEARDSPSLHENAQASADQQSGQIPCYEKLEFERAQDRDWYQCRLYGTYFVPQLLRGRTTLVMLNAKYVRKSTGILFNSNRDKEDFAASISKRYTVNRTVPRCDIPQKNWQQLVNGHVTFLFLHYQNREDAASARRRFVDDLGRPLQLKGDKSGFDVGRAPMRSPTPPNAPAPRRSRSSKQEQERSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK3</accession>
    <name>A0A8K1CAK3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004614</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK3"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000731">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000007">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000006">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475607" description="beta-glucosidase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="8">
        <location>
            <begin position="673"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="788" mass="85780" checksum="899954F95EF0ADBA" modified="2022-08-03" version="1">MLTSWFKAVCCTALALAVVPQSAYAAESAADRAAKIVEKFTVDDILGQMTQINIDSILDGNGNLDEAKVRDFAKLRVGSYLNSPFAGGPKNGKYGYSVSEWRDLVGRIQNISMAENGGHPIIYGLDSVHGAIYVQNATIFGQQINGGASFNTDLVKKMGEITGRDTAAAGVSWIFGPILEISQHPAWARTFETFGEDPYLVSVMGSAIIKGMQSNKDVAACMKHFVGYSKTPTGHDKDGVTLSDFDLLNYHMPSFIAATKAGVKTAMENYVSINGVPVVSSSKILRDLLRRDLGFEGFVVTDWAEIYNLNWFHRVAKNLAEAVRMSLTQTSIDMSMVPYEATFIDYGKEMLKNYPEYFERLKESARRIVQTKIELGLYDSPLPGAKYIKNVGSSKDRDVALDLARESIVLLQNNDNVLPLKSDDSVFLTGHSADDIGHLNGGWTIRWQGYSGNEMYPNGISVKSGFEKLAKNGSVSYFNGLKADGSYSAEDLAKAKDLAKKAKYTVAVIGESSYAEKPGDIDDLALPAGQITWVKELASTGTKVIVVLVGGRPRLLSGLPSSVHAVVNALLPGELGGQAIAEVIYGKVNPSGRLPITYPKDAANIAIPYNHRTTTQCADGKSCAMQWNFGTGLSYTKFDYSDLKLSKTKVTGQNDKVTVSVKVTNSGKVKGKETVMLFLIQPFRSISVPEVKQLKKFEKIELAPGKSETVKFELNYKDWSVFDPQIGNGFVRSAEDGDFVVAIKPETECDVYGTINNPLCAKFVLESSLVPFSLNAQERTGISIASES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAV7</accession>
    <name>A0A8K1CAV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000006</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAV7"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437058" description="Ricin B lectin domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="7">
        <location>
            <begin position="389"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="55892" checksum="1CD3CE338C00234F" modified="2022-08-03" version="1">MFKKVLAFFAIVAGAVTQAADYAGPLGSNPDPYVIYHNGYYYYTGTARPEEGGIVMLHRAKTLQELKYSSTHVIWSEKQSVEAGGPCCYYWAPELHRIDNKWYMYFSAVQKGDQEEIKWHRNYVIENENEDPYEGKWTYKGQLKDPENDFWAIDATILQLRGTNYILYSGHADNDHSLQRIYISKLENPWTQVPGRTMITEPQYSFETNGNVNEGPEILMKNGKVFMVYSANGCWTNQYNLGMLWMNEGDDPMNAKSWHKLDHSVFGSDPSVQAFAPGHNSFFKSPDGKEDWIAYHAAATNKEDCGINRFFNAKKVDWKSDGFPDFGKPVANGHLRPGPSGEPDLPSNNVLANGVYEVVNVESGRSLDVPSCRGESGLKLQQWDAFHNDCQKWIFHNVGEDYYTISAVGGGMLVSTKDCKNDPATDVWLYKPTGYDCQKWRVVDHGNGEYSFISKSANMAFDLRLGKHDNGADFIVWTSTFETPQRYRLKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAY8</accession>
    <name>A0A8K1CAY8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipid:diacylglycerol acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAY8"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="72653" checksum="A80702F091CE1DA4" modified="2022-08-03" version="1">MTSSTLRRRLGKGTDSDADDKSKPRSLQRTDSWHAKAADHVLSRRRYFLLAGVLLGIAGFALLNSVNKEMPDMTDMIQLPAESMKMIRDKFKLEWNKRVNDDFLASIDYRPLLSGSPDRPGLELKAENVTGVSPVVMIPGFTSTGLEIWQGGECSKAYFRQRMWGTARMVQQFVLNQKCWLEHMMLNRTTGLDPDGVKLRPASGLEAADYVIGGYWVWGKIIENLADIGYDSNSMYMAPYDWRLTPSLMEVRDKYFTKLKYMIEMAKATNDGRKVVVISHSYATQVIYFFMQWVESEKGGKGGKDWVDQHIDSFVSVAGSILGTVKSVSALMSGEMKDTAELGGLSRFLEYFFGPPARASLARSWPSVFTMLPIGGEAIWGNQESAPDDFASRFASPQENADGDQIVFNSSLIPQHIEQHGSNGVVLQFVNGTHANLTSTSIRKLLGSMDAGLAQYGALFAEDRPADPATFDHDHPRYWTNPLATALPNAPNMKIFCFYGVGKPVERGYVYRANDPEDDVLNDEGKSTVPFVLNTDYDDLPWVKAGIRYTDGDGTVPLISLGYMCARGWRSKTYNPSGMEIRTREYKHDPVSLIYDPRGGPATSDHVDIMGNHEMIKDILRVAARDYDNVHERINSNIEELSARVNLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAZ7</accession>
    <name>A0A8K1CAZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAZ7"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="80" mass="9031" checksum="B9BB7190099CAC6A" modified="2022-08-03" version="1">MSTTPVNNMKYRFLGNTGLLVSRFSYGCFMLMERALSFEQAYAVMERAYQHGVNFFDNADMYAGGRSEEILGQVVKAGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB23</accession>
    <name>A0A8K1CB23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB23"/>
    <dbReference type="OrthoDB" id="422779at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="556" mass="61816" checksum="836ACD7F5787FACE" modified="2022-08-03" version="1">MSAKPRIMDRVSYVSSTANNEKDKELETGYIGAVTPTVEGGALRGGGAPHLLSKQTLGLLAQYAAVGMVYGSLPSLIYPFLTNYLNMEGTATTSATALLSIPWSLKVFIGMLSDNFPIFGYRRRPFMVFGWTMCSICLFVMAFMPMPKPYFIKPEYRDLDVSELIDGVTVREDSPDKGAKYIILMMLASLGYVIADVASDAVVVEYAQREPEEIRGRTQTAIYTVRTLFSTVAAATMAFGLNGKDYGGDWDRTMSFSNYMLVLAIFCIPVIFMTWMFVHEEKVAKPNFKQYISTLWEAIQSRAFYQVIAFNFFFNLFSNQGYIASNPIQNYWAKATNLNYNISNVIGNLVFAAMLAVTGKVGLAWNWRWMVGTTAVIMVAIDAIFTMITVWDVFRNQWFWLGGPIVEQVPYGVQFIISTYVVVELAGYGNEGACYGLLTTVSNLSQPFANTITKNIDGGFDVSNKDIISDTDHVRSQVTITIWIAYACKLFALVFLVLLPSQKKAVQELKLNGGSNKHIGAFTVFYCIFALVWSIMTNLLGIFESTKCLSIVGGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB67</accession>
    <name>A0A8K1CB67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB67"/>
    <dbReference type="OrthoDB" id="117324at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="50112" checksum="D881A8DC48F5A0FC" modified="2022-08-03" version="1">MTTLMRAYSAAQGQEAPRGHEDMVIDPTLSFLDEMEGLPALVDTSTDPGSSSEDLTEELLREMLIDPDVNALLADGHGKKATRALKRNGKKPRSERYSPTKVTKPTSQARQKEEVDYLRRQVQELEAELNKLQQNHGAEAASQGALSVTSGSKAAVWKGLAERQRDAKQKAEVENVKLKEMLEDQLKIASSLEKLVRKRLGTEANEWGNMVRMSSFLPADSPESIFSSITESMESCAVEVEAFLRECGLDEVSGNFKDIKSRCGDRDDLFLEIQSCRELPFPMQATADTVWYAVNAKYMDTHGAASGSVRPLGNLYHLHFTINKVVRRSDVAVDVYAISKREDHANRVIIKWESRAFLSSSVFREKRVRMREHGCMIIQRDPAQPASSSLIKSCVRSWPEIDESAPTIRQFELIVDLLIGSYNDNMQAMYQMVENSLLDTALSQQQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBM6</accession>
    <name>A0A8K1CBM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBM6"/>
    <dbReference type="OrthoDB" id="68921at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38815" checksum="51A15527E172F343" modified="2022-08-03" version="1">MDEREMRRVRFDDDAVRTPQRVRRREAIDYQAPDATSETALPQLLQWDLFVVRWLVTMRETYPLLQGLIVVTTSKLRTQDISLFLWLFFLAMLSDLGFVYLWICIGNLLAVLLLQLLAQVPRPVDFDSSMLIPSCADPDTYGFPCVDSHMSIVVLLPVIENTQSRFARLMFVAYTVYLAFTRLCLGSRFLSQIVGSWLTGFTGLVAGNHGHVVVKAYKLSRGYNTAAIIALIVLLMFVLGQWVENNDSRIVGVPRQDFIEVLTNILSSDVPPSNTMARPQTPTPPDRARVHQWPQREEGTGNQEEEEQEEIAGRKDSFYYLIRGMRARARRQAQLTAIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBY5</accession>
    <name>A0A8K1CBY5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBY5"/>
    <dbReference type="OrthoDB" id="122216at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="23126" checksum="28A29F8760459BAA" modified="2022-08-03" version="1">MGSYLSIVNDTGDRWQCKIGPDEAALKIAGIIIGIVGTLATVIGTAGGAAPLAASLAANGVVSVLGVSTGALATITAGAASVSSVAGVIGGVSGFSMSVAKGIATQLDKDKYHAIEAGKSYRWGKMSLSLWQQGTCVKTVNVDEKTVRTETLYMRPIFSGATDKSNNDHKIQWWLNKWGTEKQEIVAQDKKRYLTEAGEGEDDLIYFFANGTNTYHESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC45</accession>
    <name>A0A8K1CC45_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC45"/>
    <dbReference type="OrthoDB" id="124272at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="806" mass="87744" checksum="44D0DA281F02E54D" modified="2022-08-03" version="1">MRHLTTRLAPLSRDATALLVGLHASSNSKEDAALRVVVRTRPNVLQFVENGQIMCVVRARVAIADVVDVGSDAKIFVSTMDGAMWLVQLPSTRQSPHKPIVLEANPSVRRLSASVPGIQRMQYLASMDTLVCTSLLMPTTVLCSVTTQPQVVEVDALEADQSTALVIVDVQDQQYHPLVCSVLAPSAEWQSSSSGVLVLQGDSDGGVRFALVDSLPRQCVHSGELIRLPEPVAALVPFRSTTGGVDALLVVGTRGAAAVWRAHGSQPRVFYPFKHPVSSIDVMDGGLAAATFVFSTSTGETLAVSVEQFLQQAFAIDSTPSIQALSLPSDVTCLACSPHVSVLCQSGRLLAFSHTHFQSLLHTTKREDNGHIDESRIKTLLHDITRVSAQSTTLQAASSRIDTLLRELDAGLRLLRRFQHRTVESVMTCAMSLRLVDGGWNQQTKRIQLRVHLQPQGEALPTPLTFWQLQLIVSDAEAHSTSQRLTSYAFPLSDSLSAGQVMVLDDEVLREQTSGRLRVTCRLLFRPSDEASSSVDNPDGLAVTVSTQDFHLIQLSEPETTTTFTLNAAKLREEASGAQGTEWWPTVQQHASDHASGVLGPPLSSAEAHTTTPVRVVLQIHRPAPASETSLLGEDEVFAIVTRLMVPAETETPESQAQWRQACRQERGKWWIGLYTFARNLVVLRLSATTSDSIEISIQATSVGDMAAMRALVIERLSTSDPSQDTESDSVARVSMAVADHRHELSALCATLEELEHVAENGVRGNGDPALCDVELLRLLDRVANMETRTLDIYWRSRDTLSAFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC64</accession>
    <name>A0A8K1CC64_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC64"/>
    <dbReference type="OrthoDB" id="117268at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="34563" checksum="EF5513A3BD49EF2F" modified="2022-08-03" version="1">MQSPGENELLPIRTNDELDEEVLRDDGVPVEARVATMVSLFGSLSGLQNVATFHCVFLELLMSMQQDSLGSAQRFFAAHKDLFEYDKYVGGEITAMTPSFLTRYQECEQRHIDTPALQLSLLVPTVTLSEAVPRPPALLSLSPPNTFQLPSTSGLSLAPTMVPSASPAGPYSHVVAAHSPPASPIRSSTNPVDQPVSSEVYHQPPSPPRRFSPRRQLHQQASLGGLLDTPRALPVLADLLVDAAQRAKHVPSQRHVDDAKKIELLIGTSCVGRVSSTTNVPPAIRRRLDASTRVQQRREQLYKLLCSDYHRLTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD84</accession>
    <name>A0A8K1CD84_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD84"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="84" mass="10190" checksum="663EB681C3C3955D" modified="2022-08-03" version="1">MARRNNRTKIKQQYELEVEREKERREKLLKKRERKAQKDSKDGKGTVVKKVSRKVLRRMQMRQAEKEAKEEETGAKAEKMEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDB5</accession>
    <name>A0A8K1CDB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDB5"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF252">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="85"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="213"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="293"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46390" checksum="711CE0ABF6699CBF" modified="2022-08-03" version="1">MSAFPKIKVVYFNAAARAESVRLAFYIGNVPFEDVRLSHQEFGALKETYPYGQLPVIEVDGEVIAQSEGMLRYAGRLTGLYPVNDPVAALKIDELLGSMDELMSKLSPSFREQDPDKKKALREEVANTIIPRYFGMIDRRLTQMKEYAVFQNDDLFIHELLINNFARWMKMGVVDHIPTTVCDGYPAIDALIAKVTSHPKVKEYYANPRNVEPKLKLTYFNGPGRAEPVRLAFHIGGVEFEDERIEFADLEKLRPSLPFGQVPVLSINGEVHAQSIQILRYAGTRSGLYPTTDLTKALRVDEVLSLIDELHNTLAPTYRMEAEAQLAARKVLAEETFPKMLSALDKRIAGRGGKFAVGDELTVADLAIYGSLLGFKSGMLSGIPTTLADSYSNIMRVHEQVANHPKVQEWTQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDF1</accession>
    <name>A0A8K1CDF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDF1"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="41069" checksum="4FC4D24910D50891" modified="2022-08-03" version="1">MELKKGLRNPLEEAQVRKAVVALQTFLEKQKAGQTKKELVSATEYVSCIITRKTIPPKSSLKPIQIDVPHSLYESDAEMCLVVKDTDKDRIKKALAEDPVAGLAKVMTVKKLRKNFSRFEDKRTLAGAYEMFLADDRILPYLKTPLGTKFFVKKKQPVAVRVSRKDVSNAVRAVFHRTVMHTSAGACTNVKIAHFGLSVEEIVENIIVGMNNCAAHIVKGWHGIQSISIKTNESVALPIYNALSELAKLPPVDSKKVLLKRKLEEVESAKTEEKASAKKQKKNTAAKEKAPEAEKPSKKKKAEAVPVAEPVAKKAKKEEPKKVAKKADKEPKKEAKKAKKEEPKKEAKKEAKKEKESAPKAKKQKKQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDT1</accession>
    <name>A0A8K1CDT1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="12">Aconitase</shortName>
            <ecNumber evidence="12">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_000459</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDT1"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000003">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="13">
        <location>
            <begin position="69"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="14">
        <location>
            <begin position="584"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW60417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="783" mass="84015" checksum="66CD6EF2B31156B2" modified="2022-08-03" version="1">MYAVTTRAARQQLRSSALKASMSTCKPAVPLSVLDPKGSPTIDQAYEKIEKNLFTVRKNTGNRPLTLAEKIIYGHLDDANQEAVRGQTYLKLRPDRVAMQDATAQMAVLQFISSGLPKTAVPTTIHCDHLITAEKGSITDLNTANTVNKEVYEFLSSAGAKFGMGFWKPGSGIIHQIVLENYAFPGGLMIGTDSHTPNAGGLGMCAIGVGGADAVDVMAGMAWELKAPKVIGVKLTGKLSGWTSPKDVILKVADILTVKGGTGAIVEYFGPGVESISCTGMATICNMGAEIGATCSTFPYTERMADYLHATQRSGIASAANDFSANLRADEGAHYDQIIEINLDNLKPLVNGPFTPDLAHEAGEDLRQASEKNGWPTEISAGLIGSCTNSSYEDITRCAELVEQAAAKGLKFKVPYFVTPGSEQVRATIERDGLLDTFIKAGGTTLANACGPCIGQWNRTDLPAGQKNSIFTSYNRNFAKRNDGNPATHAFVTSPEMVTVAAIAGTTTFNPATDSIKTPSGEDFKFEAPFGKELPPRGFDAGEETFQAPPESADGLKVNVDPNSERLALLEPFDKWHGKDFEAMPVLIKAKGKCTTDHISMAGPWLKYRGHLDNISNNLLIGAENAETGETNSVQNQFTGAFDKVPAVARQYKADGISWVVVGDENYGEGSSREHAALEPRHLGGRAVIVKSFARIHETNLKKQGMLPLTFANAADYDKITGNDKISILGLKDFQPGKPLTVRVTPANGSPFDITVNHTFNEEQIEWFKAGSALNLMKLKNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE47</accession>
    <name>A0A8K1CE47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE47"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="382" mass="42317" checksum="DD43A9104AB9E26F" modified="2022-08-03" version="1">MANPGLKTKDFVVEDNMIPRADLVGYAQRFANCLSILGAENQSEYRRSLPATDKDGSRHLHLAIGLHVRDIGDDVGQMQKQIGNLEEEKTTIVTKELPQLQETQFKVSFASKKLDESWRCSTSGNMSVEFILLVDGQTVELKIADFVVEDNSIPRASLVNYAQRFANCLEVATTSDQNEYRRSLTPSEKDGSRHLHLAIQLHVGGFDTQLEYAFLLMPIALERVDILAAQVRDLDDMIKGLMAQMASAKVTADGDGLARILNKIETIETKEKEKRELTYAQLVTTGSASANHLTWSLSSPTASSPFTMIMSSSMAMLEVSGLFLITVHFPSKCGEVFEIKVNDVVVQTLANGEGDKYDDSLAFGRPKKLRASTTLTMTERCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEU3</accession>
    <name>A0A8K1CEU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEU3"/>
    <dbReference type="OrthoDB" id="432686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="41468" checksum="05E4820F095AE6EE" modified="2022-08-03" version="1">MANADYKLLTPLVLGKDFELKNRVVLAPLVRARANVDRTLSELQEIYYEQRAGAGLIITEATAISDQGHGSYRGPALYKKEHADGWKKIIDRVHAKGGKIVVQLWHTGRKSHPSYHEVKESVAPSAIRVESGSTRDANGQNTKYVTPRALKPDEIPGIVENYRRSAELAMQAGFDGVEINSANGYLLDTFLQSATNKRTDNYGGSFENRARILFEVLDAVMTAWSSDRIGVRLSPNGSHADMGSEDNFEFFTYVMEYLSTHNLAYLATIDAGGFFGFHNKCRPMTVFDAKKAFKGTVMATSNYDRNTAEGALRSGAADLVAFGRLYISNPDLAERFANDWSVSDLPSEDDFLGRAVEGKDQGHGYIDFPAYVQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFW2</accession>
    <name>A0A8K1CFW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFW2"/>
    <dbReference type="OrthoDB" id="114078at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="48665" checksum="33002AF8E11A2825" modified="2022-08-03" version="1">MKRVNPRRPSIPTLSLSPAEEHRIENEAAALLTQTLQIEHDFFANDSEVNEEHWKQLKSSDYFSIYKERHTTTESHDGWDPSASGGPKTRAASLDNDALISSKKKAQIPMIVSTGHVEGLMEDVVFGFAAGDLPSWRMRTAFTKDRFADAKILATINKPTEERPFNYLCVKWFVSAFPALLKVFVNPRDLLVLEASGVKVDTQGQRYGYYIIHDYVHPMIGKMDEYGICRCSISMCFIMREVRPGKVHIFSRGFVDPRGDMSQNVVLMLTSKAMLTMAKTPESSISKKLVWLMARQERERQDKNQRGRMSSTESVESGTCGSCGKPPGFLKSKLATCRLCRQEFCSRCIVEQRVVVEVTRKEMNERSFPFCLGCILKTKKMSPRAVALDRVRENAARAESSSSSERSTSNLSSAELFSIPSSPSDSDGADILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGT4</accession>
    <name>A0A8K1CGT4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">threonine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_005351</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGT4"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000039">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF44">
        <property type="entry name" value="THREONINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="344"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="733" mass="83949" checksum="0F1715BB75841C46" modified="2022-08-03" version="1">MRQWLRTGHALGALRRPRAALGFSHVTQQHGMVLSRALSSIASIQEWRVSKWEAEKLRQSEQTKALDGDSIAVTLRLGEQSHVFEAVAGASTAVDILKQMQELGLPKVQQALAVAVNGGKEVLDLRHPFDKDCSIEFLDFSSDEGKKVFWHSSAHVLGQALEEKFQEKIRLCDGPALKEGGFFYEMFLQDNLTVSESDFSELQAHIKKIVKQRQPFERLEVSRDFARELFQYSEFKLQMLNKIPATEAVTLYRCGPLIDLCRGPHVPHTGVLSSFEITRCGASHWEDRDLLQRVYGISFPNNALLKEWQHLQEEAKKRDHRLIGKQQQLFMFHQLSPGSSFFLPHGTRVFNKLANFIRDEYRKRGYQEVITPLIFKKELWETSGHLQNYHEDMFMVSQGIHNGCGHDHSHHEHGEGEGESDHFGLKPMNCPGHCILFRESKKYSYRELPVRFADFSALHRNEASGALTGLTRVRRFHQDDAHIFCMDNQVQDEISQCLSFIQHVYGVFGFTFQLRLSTRPEKYMGELAAWDSAETQLRQALNDFGEPWTVNEGDGAFYGPKIDIVVMDALQRQHQCGTIQLDFQLPRNFELSYDGADGQEHTPIIIHRAVLGSIERMMAILIEHTGGKWPLWLSPRQVAVLPISEAHQEYAQEVAATLEQQGKLYVDVQDSNKTLNKRVREAQLAGYNYILVVGEKEQENQEVNVRTRDNQVHGAKPLTTFMREVQEAIERFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHJ4</accession>
    <name>A0A8K1CHJ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHJ4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000286">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="58"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="445"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="55656" checksum="8417D33201DCACBE" modified="2022-08-03" version="1">MLTMGGAMDDQAMFSSPSLSAKAAVKRESKFVIKTLPESAKPSTGLIGKEIAKRSKPDAPKFLLLLYEILHAESDKVIRWSDDGLALQILDQNTVTEKILPKYFNHTNFHSFQRQLNYFGFRKWTKSKTDICTFSHPYFRRNQPELLQLIKRKKAARRTPVPEKPEEYSSQSDGRNSSVSSKRLLPLSPSGKRKLPVDANDNPTTIAQALPTLNTSNVHIHPAANGLSPNGPIPNGFGGDIASHQYHPSAVLTNAISPVAAQGCKKKAKKNEKNAYVTAGDDTDDPVGSATLTVNDLANAPNMERLSPVHGYNKGTLPNLDIVRNRLIRRQQISGTSVAMDGYAHTMDTSPHGAAPMILSGLERINASLPAAPVAVGESSPLFSNSFSDPVDILLRIKKSRALSTDSTHMQSPQQPPNDQADNMASLQNFLLSQSLYTNRLESQLKLALEENDALRVMVDAKQREVDALHNERKLLQNEKSVLLEDKNKLYEINRDLLNKLFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHX5</accession>
    <name>A0A8K1CHX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHX5"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="481" mass="52347" checksum="9B2AA41D55D2BF7F" modified="2022-08-03" version="1">MGSVRVGVKCGQIAVFEASSSVSSAAGPSTEIIRGGLRRTLLPRGLELLRAAGIQQGEVFILVLDNNSTSVACMLAAVNMRCVCVLLGVSRIGLLQHVVKHTKVTTIVTVRGETGTLSVQKQPGEDSPAWTQDPAIHSEGGVCMLTSGSVGEPKVAACSWEAMRLQGQSTHEELFPEGPARIICGTSISHAYSINAIFTLLTSPYDEQSELCFVSDVKALYDLIAVKHDKRTVLYGTPATYTQLLRLPAKPLYVDVPYSAGTRLSLELFQQTAQHSGLCVMQNYGSTETGDIAAWYLHGKRSPEESKHMIEAKETYVGTLWPGVRVQVEESTEEVLVWTPWQSMGYVVTGELRLRNGAPHRTADRGREHLASNGVTSLWLQGRIRPSIQLSLSGLILSMRPEQIEQVFLTHEDVTDVLALMPVANPASTLRLRVVLRDGCTLNAKELNQWGAEELNLPPDSVEIELVGFLPCSPAGKLMYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI55</accession>
    <name>A0A8K1CI55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI55"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000018">
        <property type="entry name" value="Oxysterol-binding protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF148">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="31"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="8">
        <location>
            <begin position="357"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="99422" checksum="B87FF32B6D684369" modified="2022-08-03" version="1">MHALQGLTDRVHSDSSRHRKPVTALPHYDSSCMKEGYLQKKGQRLKGWKRRWFVCDGRALSYYISRKDRKPNAVIPLESCSVQDGGVSETWNSPRIYLTDGTCGVMYCLSGEDAAVVTAWLNVLRTAVTKVLAGDLQHQTSGYESAERMESVEPVDKPLVKRLVSDDEEPQSYKAPPSNGARTMALASADSIVPEKRTTRLVSAPAQVKAQRTKAEHHPTNITLENELASGLDLLEVLLTNRNVGRGGVVFRPIGATNGVLKSVGADPSGVKFYARASTILPVPSDVASFYITDHAKRAEWDIHFPHSMHVASFDEATDLIHISGGFQQIESTKPFVTPQLAAAAGSLLGALLASSWDSMLVSAVIAGIVGAVLNSIEYSVLCAPRDLVLVRHVRESSMMDKRVASSSDIMEDGEDTPPVVMILEKSVVSELKPTLDGAVRAHVGLSGWLLEPVEGDRTRATYVSDLDAKGWVSPATKKDFLLQRLGCVSVLLEHVTQSQLSGTDPLMDDDRMSVDGDVKDDDLRRAVAYVDDRSDVVATSREFHPSVYMKGMMQIPSGGLKLVDKEVAKKQGGVLKDVIKSAGAKILEGKGTVSLSLPVRIFEPRTNLERVVDLFLYAPTFLNMAADQTDPVERFKLVMAFAVAGMHHSVGQLKPFNPILGETYQSVLNDGTDVCCEHTSHHPPVSNFQLVGKKYSISGHVLWHGSFSMKSNAVVQNNRGPIHVKFEDGTTISFHLPVMQSGGFLWGDRTVELLGNVLFEDKKNRLVCDLKFNPDEKKGMGGMFSASKTPSDQFRGAIVNAVTGSELCDVSGSWLEELRFGEKAYWRYGRERSGYTLPMPESQVLVSDSRNREDLRYLAMNDLDTAQDWKVRLEVLQRADRKIRNEGRRPNHWALRDEKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJZ1</accession>
    <name>A0A8K1CJZ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJZ1"/>
    <dbReference type="OrthoDB" id="63815at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="26581" checksum="5C043AEDFD303D56" modified="2022-08-03" version="1">MVLFHWHPQATRQSRIRSAGNMASLGDEERELIQKDREENPGCFYSTALSQSCRSVNGDSKCEIVKKIFRQCPGKNRELISNRKEVTEDEHAGEDMTKDDFFNHERMDSRKGDLGSFFDPFRQREDDFEAQLSPFDFFRQEMLRPFESFFGGGLFGGGNGSLFGEDFEREFERMPVHPPSRRPSNQPPPPSNPPHYSYHPSEDARRGRRSARSDDKKDMFAGYKGPVEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK71</accession>
    <name>A0A8K1CK71_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK71"/>
    <dbReference type="OrthoDB" id="155171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443763" evidence="1">
        <location>
            <begin position="21"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="55159" checksum="8EB406FA1854D649" modified="2022-08-03" version="1">MVQLRAFGLILAATALQANAYVAGENDALQHWIGPAIGVPIDNACYRKTHPTKKCPVGYNSDNIATCWAQCPLEYPVECGMECLPQNADCTKAVLRKVGAVANVALTAASSGMFGQISLASKGVQQGVKCGQQIYSTVQKVTGYVEELENSGKVNSTSDELMFLLSKSDFVTFDLPVAVATCLGLPVPTGLTKANDIMSKVKAVTEQIITAKKGGANLLDPQNFIKLIKDVGFSSALPVLKSPEDVNKIKETVNKGLGCGDALNKIVNRVVGMIQEIKTKDASTTVESLRIAVLGSDLVMKELPDAAGGCFKVNMPNAFQKRDEVLKAIHVVLDGAIEASSNKEKPLSTADYALKITDMGLGAIAMFDPTGIAAMAKEFVQPICGPTVFVGDIDDGPADQALGLRTVQKAFKDSKGDWKKQGDGQAHITFKSVDNKDVEVIIKSGGQVHAKVKVGKGKTVEWSGPLSELQGKTMYMDRWRPGLLGISGTGGGSLLLWIPSNASGSLKLDVTINPTSFSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM27</accession>
    <name>A0A8K1CM27_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM27"/>
    <dbReference type="OrthoDB" id="96750at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067:SF3">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="53009" checksum="34FB540ACF65B165" modified="2022-08-03" version="1">MADGASHDSEGYLDVRMSFGFNGQLHNYHLLAIPMQDRSHSGFNYSDLVLDVMKNVFDDSILNKLIGITSDGAATMLGCRQGFSTRIRLACEEVGGRGISINWCGSHQLNLLVDEFLAAFDEIAAFRSTLGSEITFTRKFDTVHSVVGKCPTYATTRWESIHHTCKFMAEKYEQLMECHEGKTYNKPSSTWWLCLFVLADLTKAIKNCFKKMQYQNVTKHAQYRALTELATTFQMQFEEDSDGTEPIVSRTKVSDFIKMASYSSEDMYNELPQAIQDQVVLGMVHAIARFIVGVKNLSIEVNYDDAPSPTILPAELPDLKPSAIRDLIRLHEERLKAAFGDTATTVIWTEYQHFLRRSKSDSAFKRLLDSSKRERFEGAWRQVDPERKYWHLIEFLAAFPAVSPGTHQVEGDFSDLKRIKGQHRSCLSNYAMKGQLQAKQYFALISLANDIGYQDAINEESTEDPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM53</accession>
    <name>A0A8K1CM53_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM53"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="83" mass="10166" checksum="8BC3C1664C153C3D" modified="2022-08-03" version="1">MHGNMRHLYERLRVLDAVLNDLEESQEQVELARLTIIRLQSRIVQLRLRVRRLRNPYFRQRMVRFQTRTGQESIPQQTEQHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMT3</accession>
    <name>A0A8K1CMT3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMT3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="37436" checksum="0927D0325C21AD9F" modified="2022-08-03" version="1">MTMTLDRDDLFAAAASGDVATIERFFHQPANQPAINRVNRLLREDCDAALARNESPFSMGQPRTPDEWYYRPSATRAYMFDRLFDEPAIRGHVQVFAWFCGATATTVIGDTIRSLIRLMYLSVLKNRTLHEELADVILSSLLFHSMNPLEQKHVFTMMLKAAIVYGRPENLEAVASSGGVWILHPFVVKAATTSKYEAPEFMIRQGMDAQAEITEQGFVDVNARSLDGVTPLMKAAGPGPSKWGKNGLETLFTVHMAMFWQHYWLTALIPMPKTTTGPPLHVTPERVKLAHYEDRLEMMLADKAGVSPYDPLIRTERGQSFVEAHPEFFKPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMX2</accession>
    <name>A0A8K1CMX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003603</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMX2"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF12">
        <property type="entry name" value="ASPARTIC PROTEINASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453042" description="Peptidase A1 domain-containing protein" evidence="9">
        <location>
            <begin position="34"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="51"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="570"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="603" mass="65628" checksum="A43C8238D47756B2" modified="2022-08-03" version="1">MRVRRRRRQSHVYNMRAGVFAVVFMALAGPVDAEKAQYSLDLYGISSGAAYTVEVDVGSSGETAPFRLIADTGSSNDAVLGAGCCGSGATVTFDCEASSTCQPESTQNTLEFAGATISGHFVKDKWSSSEIGSITKEFLVIEDQDTFYRTEYDGITGLAYKKLAAPKDSPKDAFYQNMVDAKSTKDAFGLQMCGIMQPMLSSSNFSLHAGQLLVGGDQGLKGEALYVEPMLYTPIIQEAWFVVAVSDVGFDGESLGLPCSSYNDPQAIIDSGTSNIAFPSDVYNALMDRIKTATKKTVPDFDDSYFDYSKSCCGEDYCDPSDAKAALLSLPSIYVTLAMSEDGSSATNLHYTVEIPPEYYFRPEMNGQNTDVPCRAIGIAEGSAIVLGAVLMDGLFSYHDRENARIGLAVAKNCPNGVTSTKKLSIAESKTDDWCKCFSKNLQKRSSIVTYFPWGSGCYYVPWWMYVVIASVVVVVICIGVLGYWYWSGRRDKQKAQAHTNGGSVAAQPVTIAPRNNRSETPQHDKQSHYAAMESPREPLDSGGSSIVMLTTSSREEARKTGKQRRRSSSRTSRASSSSTRAPSHARADNQQPHHRETDGFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNK8</accession>
    <name>A0A8K1CNK8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNK8"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="463" mass="50994" checksum="48EC51AF875D8CB4" modified="2022-08-03" version="1">MAVEQVEELRARGNAFYGAGRFEDARACYAEAILELESALKGVDVADRAVVGAKLAQLFSNRAQTYIQERNFAPALQDAARALEYEPSNEKAAVRRLVSFENLERFETAFQIVERILDDSSTRRAQPALFEYAVSARRRLRKAVAQDKAAAQQEQHAIGRMVHENQQLRINFGCLIPSTVVVGQFFDVVVNLGNEFGLFRRDYLQPGEQIHLQLNLRNNADGAFKLVFRETTDPLTSSTSSGPETNGKISLNERGKARFQLAIQPASSTAAGRSNMALALTVHPDSADRWNLLSIISLPFTLYTKAPLDEVNDEDDIVSRLGVHCCRPVNLPGLDQEILLAESPGNLGIGGKLWDSCLVLTRYLSANKHLLMGKSAIELGSGLGLVGIYCAMLGAHVTLTDIEEVVPLLDYNIKLNFAKSEGDALIPVAVSHFWAQQPRTFLRLPMSSSCLTLCTIQKAMSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNV9</accession>
    <name>A0A8K1CNV9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004309</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60292"/>
            <dbReference type="Rhea" id="RHEA-COMP:15535"/>
            <dbReference type="Rhea" id="RHEA-COMP:15548"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.356"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140951">
        <property type="term" value="F:histone H3K27 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10519">
        <property type="entry name" value="SET_EZH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026489">
        <property type="entry name" value="CXC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041355">
        <property type="entry name" value="Pre-SET_CXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18264">
        <property type="entry name" value="preSET_CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51633">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CXC" evidence="9">
        <location>
            <begin position="1101"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="1222"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="819"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="884"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="920"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="982"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="884"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="920"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="930"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1369" mass="152246" checksum="521AA60C7E3511FB" modified="2022-08-03" version="1">MVRKSAPSARSYNHAVGREPVARAKDEDEDEDFDEDDDNDDDVDVAYGVPMFAMKSAPSGVHYNHAVSIKPAPTAGYKTTKKSAPTAASKNHANGSVKHQRELEDSSDEEDYHLGQHAARTATRRLMVESEQDDLDDDSDDDDDESDSAMTQKVAMKTAPSAARYNSAATAKRQRAGDMDGDVEVVKTVKLPPSRVIKKADLVAPSPPPQRRSSGNDVGLLSEWLSVSELQAQEREWARLQREKRNQDAHYHVEKTEHGKRKSVRDDILAQTQGDNQSASSEMSLIEVVELLEDEDEEMSQKGEDDDDDDFMPSSSWSQKSSHKRDSKKKTDVAKKRAHHRKMMAQNGASAVNGALPVVSDTLPKARTAADTIPHWTTWRACAFAVAPTNLLCDWRMDRLSFTSTVDRPLSEYDKSGELGTKCAIVTSFGKTKQFVLTNDAVGATSTQEDMNSRVTQLLEKWSPHIRQCYERKTDAIVREARSTIRGYLQKLDVHRHEMLVSRNRGLVRARRSLDVCSAERVITKQLMRSSMLSPLEESNKLGYTIGRGESFLSEKSILAEVAVVLAPMRQLSRSTTYVGVKASVRVEDDPILRHVPYFGDHDSGDAIDVKHYGSIRKREESGPSISSGLEHELHEYMLRLVIAECGDAEIVFNSLKQVAGFTQPYTEYGEIKKLHDARRASAKRIVEVREFLSQVDNIGESSRQSIAAWSALSTLTSTLPPFAGGSRVNGALSLSERLSAPFTYFETNLLPPSGLSKKAGPLGLRNTSDYADLSETFRDLFCRMCYKYDCHEHGIEHPMPSRRVDPIYPNTRYAPVLIAKETDKNTKEGGKTDNHEDTTISDVNASAEEDDSSAETKQKNADSSVTSRPDVLDLAAEFSGVESQESVELLSSESSQAARRRSARSQTVASTLATISLESQMAHSSARQRVPRTQRSRSAVKRSKEDESEYLDNSHAMLLSDKVKTFLATDGLCSDDCWKNASSQETKGTPTRPADGGTSVEATSVFNEPNERVKDRLSATEILLLQKLRYTIGDNPCMISCVLESLTCRDVHTYLVGQQQRRPLGQGGCFSPDVGVKKTRKRGRTSTALPQNNRELLKRTRHQRLKDTSAFNHEYEPCNHEGICDFGVGCSCMKRDHMCEKACSCSRDCPNRFLGCRCSMGNCRTNACPCFVAMRECNPDLCFTCGATDMPVLIYNPELRRLGALELGICCNVNAQRGLHKKIGVSFSTTHGWGAFAREPIRRGEFIYEYNGAIISHDEAERRGSIYDKMAISFLFDLNEDAVVDAIRSGNKIKFANHAAVGQKCLARIMRIGGEHRISIWASADIQKGEELFFNYGYHGESAPDWSQVRITGSSKRGEADKQEQHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNZ9</accession>
    <name>A0A8K1CNZ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNZ9"/>
    <dbReference type="OrthoDB" id="123392at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="527" mass="58930" checksum="9AA06DB004D35B01" modified="2022-08-03" version="1">MRAITVHPVVAAEASRISSRSLSSRLNAFSVAPSKAFLRIVSVLTGFGRIHQRYTVAKLHEFEHYRQTTSLWRVVGILLSTPVLGFLGTLFPVWIPLQDPRLGFSNNPGSLVHYFLMVVLATLGATLIPRACIGFTREQFSRTKVGIIVGCVAVSTTGVYAIAASIWRFPVLFAIILSSAVFCPSIILCHSFLLKDLLAKSSPYRKQLLGSVPWVVVRCSQIVIYPAFTALFEVVDAGHQILLTLAFPILKHCIKTISRKVGKGFNDFNEEMAVTGVEISASLYQSMLMQSTPSLLTTAIIIMVDVVHGLLGIKVFMDKPSIVTRHAVLETALRHIEKSRLEKKSVTWADLRQSQFRPTMASDKRKVMIEEQQLGDVVVIQALEILQAAENILFVEYFGVAIPIVNVIYLAIASQADSARYNPKLAPFHASNERLVDGVRAILVYSLLQSVTLLAMLAVMRYRYRLSTARLLSFILERHWWSLQGKMIGWLPLFLHFSLLHYGADFKFKFDIEHSVQDTESQQEVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPK7</accession>
    <name>A0A8K1CPK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPK7"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="426"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="671" mass="74815" checksum="3AFCE95BF46BD7F6" modified="2022-08-03" version="1">MHMRWEPLRVQDAPPTIKNHTATPISRTELLIFGGYDGRRNHNDLYLFNSEAATWTPLTAPRVHGSPPAGRNGHSATLADRKVFVIGGWLGSGPLAADDMHVLDLDAMEWKQPPVLGTPPGPCNMHTADYIPHLRSILLFRGGDGREYLNDLHRLDVDTLVWSRVHASGRLPVPRANHSSALVDESQIVIFGGWDGHKRLNDIHVLDTYTMVWSAVDVQSNTPFGGSLPHPRAGMSFVRHRDHVFLFGGSGPSAQCYNDLHIYDPHDALWLDVATLPEDHQLCATVHALLTDGDDESDQEGRGVALSPHLSNSLDYYSEYEDSPSALSLYEHHNSHANPNDTHSQRHPDQIFVVGHGPGRRAGHTCSLLEDRKLFVFGGSCGNEYLNDMYVLDTDPPPRATITCTTSPTLVLQQALRDFVNNEEFSDISFLVEGRIVYAHKIILTLLSDRFRSMFTGGFREAQQKEIVIPDMRYVVFLKMLEYLYTGDFVDDSIGGASGYSENDTLIEHPGGSKGRRTSSVYEEASDDDVFASRQDGSAVPERFPSLQHSDALGKTQMVDLDVQLDLLIVADEFMLDHLKQLCERSLQYSVTMETVMDVLAAANQANAAQLRAICMHFLRNHDIEWLEEDEEDAEHDQGADTVNECTLDDEGPVGFAQWQDGDSTHEPVMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQH2</accession>
    <name>A0A8K1CQH2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011952</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQH2"/>
    <dbReference type="OrthoDB" id="568194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443285" description="Apple domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="23"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="183"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="254" mass="27444" checksum="E74BB6734CF71822" modified="2022-08-03" version="1">MVLQHLVLFTALAVGVSAADRRCTPIQRGTQFGGTTISTTSQANYFYCNDLCRDNTNCAAYTYTVSSSQCVLFSASTTENTDYSKRDNLYSAHCVTKEASAKLYGPSEPHTDYYGNDLWSQAAATATDCADICQYNWDCTAYTWTADNGGVCYVKRFKSETVTVSPAPSDGSVRIRSGEVYKCSRPMYDADITGQDLGSVLRSSWMECCGVCRNTANCNAFSWNNYNGGTCWLKTGAAGAMPQASGVISATLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQP5</accession>
    <name>A0A8K1CQP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQP5"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="471"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="574"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="574"/>
            <end position="578"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="617"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="735"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="735"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="853" mass="97271" checksum="8159C0F7CDA72754" modified="2022-08-03" version="1">MVTFAGLTPTPPPGGTSAKGHSAGSAEAHNANAIMNQERVNQRVSRIYPLTDSVIVSKTKKTPVEVKFHPLTSHFMNETRLEKLYQVTFARENAPRSTRIAVIFMVLYLIFTGSNLGNLFSSDAKTRSESRLYFYLVFTPIVPIPFLIYLGRVRKYEIQFQRIYTVILLCWTFSIIAGGMYSMLTEWYNYVVKDFNVIMGILELNVTDAPRYYINDTTSPGWQFKAMEGTAKELLLEYTREILLPAATMNINLVRLIMVFVFVPLLRIDTLHFTIVSLVTCTAYGGLTIAYYPAPDSGPFVQNRILVLAFPIVFALVMLMRNRDVDRVVRQDFLHVWAVELEAEKATREKNLIAEENRNLKKELAQRDSEFTLDLTSPLHSILAELKLFIDETDMTPSAQQRGFAILRNLSKLDTNLFMPDIRAQMKGKDEEVDKDTKNWALSVLTAKNYQGTGRAHATMSLSSHSNSDNTRRSYQDNIGGMIGANGALIIAPLPNMPLWEDELLDRVKKRIHQDGWDLDTLQIAELTNGRPLMYVTAAMFDIHELHEEFRIDRIVLRNFLFTLDEGYLANPYHNSSHAADVVNSVNYLMTRLNDGQIRDTLTNLEFYAALVAAAIHDFRHPGKSNNYMIKCKHDLAIQYNDRSILESMHLAETFFVMRNPLCDIFGRMKDKPYREIRKAIIEMVLSTDLSMHLQLVGNLKALMIQDQSNPSAGPNSRSVTDPMMIMKVVIKCADIGHAAKERRLHVIWSSLIIEEFFLQGDNERANNSDISPFMDRHSENSAKNQVGFFEFIVLPFYDTVSSVVFDKDFSIIHGIAKQNYLLWKESDKRQLTSIVAIKHEVFLNEKVQVSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR94</accession>
    <name>A0A8K1CR94_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR94"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="201" mass="23004" checksum="0A956D31ED15A7F6" modified="2022-08-03" version="1">MTGARAPRDHQFHLLVVIPDFMVWKLTPARVGPHWDRSLSVEKQAWQSVVRVVVRVASHVVTSSTALVVVRTARHVYVQTNMQMWRDERLRVHMSDAFKAEFEKNVPEIVEELRLPTGLGDGSHAVNWPQEIAMNSRLQIAIEQLVGDDDDDQELCQVLRFRLCWDCSASSDRVIFRIRVRRRAGARLSSLHSAAVSRAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRG9</accession>
    <name>A0A8K1CRG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TATA box binding protein associated factor (TAF) histone-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRG9"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000005">
        <property type="entry name" value="TATA-binding protein-associated-factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="6">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="429" mass="48342" checksum="0DEBA7AD7DC938B3" modified="2022-08-03" version="1">MSLLRSETLKVAAQSVGIEDLSDACVRELLPEVELRVREIIQDALKFRSHSKRPQLTTEHVNQALQARNVEGLYGFGAPGAAKFRQCEDQKTLFFADDDEVDLNEVLNAPLPHVPMQPALSVHWLAVEGVQPLIPENDAVEDDSTRRTAIKDEAFVGQVDRKPLVKHVLTEEMQLYYTKVTDAIRGDDFELQRAAFASLAKDPGIHQLLPYFSRFVYEEVKHSNNDLARLSSLMRVCRCLLVNQHLRIELYLHQLLPSILTCVLGQQLCENPADDHWALRKYAAQLVAQICQRYGETYEKIQARVAKTYHQAITDPECPFITQYGALHGMMYLGPLVLENLLFPNLEQYLKRLQPALSSSNANVVERLEAQNCLGILVHASGMYFSMAEGMDRDTSSVSIRDIMGLLDDAFGERLVPYTNASSTLTLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS07</accession>
    <name>A0A8K1CS07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TATA-box-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS07"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00652">
        <property type="entry name" value="TBP_TLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="192"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25385" checksum="251BC50800DD5A68" modified="2022-08-03" version="1">MEETWTPARLEELGVKPRVVNVLAHGHIRSGIDVKQLALLVRNADYKPRGFGALVLRFQDPRASIMVYKSGKFVVVGTTHPDEAKVALDKFLSILQKISFPHELGSFTIANVVGSLDVKFRIRLEGLASGHIRFSTYEPELFPGLIYRMLRPKCTLLVFVSGKIVVTGAKIDEAVCKLYPVLLQYRLRSSQSDDEDDDSMDGSEEEGYAIDADDELDDGSEDEDAILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS11</accession>
    <name>A0A8K1CS11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS11"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="30749" checksum="E6F2D7279D44830A" modified="2022-08-03" version="1">MASSSSSAKVWLITGCSSGLGRELAIAARKRGDLVVATARKVEALEDLKKLGCETLALDISASEDEVKQAVDTAQAFYGRIDILVNNAGYTTLGTVEEASDKDLLEMFDTNVFGHQRVIRGVLPYMRAKRSGVIANIGSGAGYTAIPVNGVYGATKFAIAGLTQSLAQEVAHLGIEVTVVDLGIYRTSILSHERSFKHAIEDYAPVKKAVLEMMATGVGVRPQDPAKGAQALVEALTKTGRCAGLTLPRRMPLGGEMMPLMDGELAAREKEKNEWVAFTKPEAFAFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSL8</accession>
    <name>A0A8K1CSL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSL8"/>
    <dbReference type="OrthoDB" id="159553at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035466071" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="303"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="46151" checksum="783EE6681F30BB98" modified="2022-08-03" version="1">MNIVGVLSVASLLVVASAQEHSYSFKDYNMRREGRAEAGRVRDTEANASVSFQEGENGWVTAKNCDFSGNDLTFQFGKVATCQKACEENEECTHYSAWALMCWLKSGDSAKATRPGSFYRTSCGYLQDRFQVDGSDNEPSPSSPAPSSAAPSPAPSVTAEPSEAPEPSETPEPTEAPEPSSSAPSKTPEPSTEAPTEAPSPVPTTNAPTKAPTPPPTTKAPTEAPTPPPTTKAPTKAPTPPPTTKAPTEAPTPPPTTKAPTKAPTPPPTTKAPTKAPTPPPTTKAPTKAPTKAPTPAKNDGGVDAEACLAAHNKARAEVGVPLVTWDEGLAKKGQEWATHMEKNNFFAHSTPGKNDAQMNNLFSGTSCLDAVNAFYSEKSKLPADRIVRAESYTQYGHYTMMVWRKTTRIGCGRGPTKNIACYYEVPGNMLGQAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSN6</accession>
    <name>A0A8K1CSN6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005977</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121574at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000077">
        <property type="entry name" value="Putative Unc104-like kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.50">
        <property type="entry name" value="Microtubule-binding protein MIP-T3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040468">
        <property type="entry name" value="TRAF3IP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042576">
        <property type="entry name" value="TRAF3IP1_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10243">
        <property type="entry name" value="MIP-T3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="11"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="9">
        <location>
            <begin position="1016"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="591"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="981"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1588"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="348"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1131"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1448"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1539"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="601"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1007"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1604"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1681"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1695"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1754"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1774"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="94"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1783" mass="198488" checksum="CF5955D5399CF4A5" modified="2022-08-03" version="1">MKDEKENEAENIRVAVRCRPMNDRELREQAVSCFVAEHGNAVLTNLENPSERHEFGFDHVYGCDTPQFQVFNDIGVPILDRAFGGYNGTIFAYGQTGSGKTFSMSGVRGKEELEGLIPRMNRAIFERISAEKAENPNKLFLVECSFFEIYNEIIYDLLDASGNSKKNKGGLEIKEHAVLGIYVKDLQERVVESRDEVIELMTQGAQARTVGYTQMNAESSRSHSIFVIKIHQKDATDESKNIFAKINLVDLAGSERAASTGAQGDRLKEGANINKSLSALGNVINALVEASRTGKKVFIPYRNSKLTRVLQESLGGNSLCSMLATLSPANINFIETLSTLKYASRAKSIKVNAKKNEASSQISQLNEEIAALKKRLLEQTSTTLGLDPKEKEEIVSKYEQQIKEMDRIRLQTWEDKAKLSKQHEMERKRLAKEKALADQKIREERPRKWKLLEEKGDVELMLRALRDLDRSGPASSTKTCAEDQWLSKAQAMKTLEGKIKDSRTLIMVFKDSLDKDVDQWAKRLDSKEAISGAAKRDESAAMHMISNQLCSKLQNIIDESKVLMSMEAKLLGDGSEMVNEMMSELIQFKQKRAERKAAKPSTATAEGTNRTASPKDDGQLVEEHEKGLSITLALFLRQRSTILTSVKTERSKMFNFAPVTCQFMKYFDARVAAPTQDNSQSREASEAWNKLKSSLTEANIKLDATMKAVGGATIETLMRYAPKGETAALGLESKLIADECLHTSSKKADAKLVRLNSPQFWIREEQDPVPFVVVDLEFPRFVDSVIIRGGPTSGILPVRANGSSAVGENGSAGGDGSQATTTVSTFELKSTEELINALQNYKLDEISGDHEPTHAVLSYVMSWMDLIKSNAVPVKLFARPPVRFLHDVISAVVRNTGFAKDLFTPNERDFTKLESKTEKMDFLNKIIDFVQDSYRKQGENGADRVIIAATASNILAGKEPMDTLKFLCYLGLAAIQHAIQHPPSRSAPSPNKPEAASSPQPTDVSDNNNTNTPEETGPEATEEKQGWVKKLRISTSLTGKQWRVIGDFDGNADGENLHTIAFKSDANAVGRFVQLTCIEWHESPLIQLELFGREACENNELISTMDSMATQAGMVLQHLLAAASMLAEEARTSLQRAKDVEREKHEELKQSMAEITKLKSTNAAYEKEIKELQQCKTTLQENVKAESKKLNDEKAKGEKLQKDLQQLTTQFGDLRKEKEVLSAQVNEHARTIQTTSLQLSEQRKDMELLQKSKTDLEELCSNLRNQLQTKSQNEGHQESKMANVLSDLMSVNVQLEEYKRKWESSEQMRKEQEAATQALHGQLQQQLAVMNEKEARMQDLLKQKLTEADKAAEVLQSEKDELTKRLDDYSALETTLRAASVALEAEVAAVREEIEVWKRKVVPAPSSPRKETLEKTLRESEQNALRAAAGEKLLLEAQTKELRSMAELEKMELKLQACEQKQKEAEQRTVEVERERDALSRRITELEEQDEELQLQIQVVTEERDAARLKEEQLFGENNEKDQEIERIRDGYVWVTDRMNSKEDELAEMQEQLEKYQALLQITGSANASKEKKSGDADESAYLKKLYDMTGGNSTSTGKSPADLMKHLEQWVEHANKLASTKKALPTSEDPAKPSQTNGVSPNPTPPPKPAMPATAEVKASPRPSSAVKQVEPSCPQAIKPSAPATTSASAMLGVSNSPPKQDNQLPSTTASKVPDHSTVPQASLGPNKAPPTATGKTSTSKPETPRATIGNNTEEDAYDDDFDADDGDEAKKLQRRKSSTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSQ4</accession>
    <name>A0A8K1CSQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein transport protein SEC13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_001031</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSQ4"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000655">
        <property type="entry name" value="Protein transport protein SEC13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="204"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW68875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34188" checksum="CDE92D44EB430A9E" modified="2022-08-03" version="1">MTAPILSIDTQHEDMIHDAQLDYYGKRLATCSSDRTIKVYDVTGDVQNNEQMLTGHEGPVWQVSWAHPKFGVLLASCSYDGKVIIFKEQSLNQWTQAYVHAFHEASVNSIAWAPHEYGLSLACASADGNVSVISYTAEGWVVTHFKDSSLGCNAVSWASFNSLGSKGETGLIQRVVTASCDKTIKIWSLAEGHTEWTKQEISSVPAHTDWVRDVAWAPGSGAPVNLIASCSEDKHVYIWSQSEENGPWKRELLHTFEAPVWRVSWSVTGNVLAVSSGDHKVTLWKETLDKKWIQISSVDEAGALHDGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSY6</accession>
    <name>A0A8K1CSY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_001166</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSY6"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="65"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW69010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="505" mass="55148" checksum="CA97CED1C8829718" modified="2022-08-03" version="1">MHSFSFTILPQDAMTTGNQMAIAVSEDQETSSFVQLPSPKLHEVFEPTRPTTVNRLVYTSSVLALFQVIHFGWSLFQLNFSKLNNERDCEARPVVSGTCIMFPGHSSTEWLFVVNSWIVGGTVGALSSGYFADRFGRKKTMIANCFIMIAGSIIQASAPNLPVFVIGRGVAGVASAVGTTLSNGYVSEVAPPHLRGAIGTLYGFAVALGVFLVCLAFFVFDSSDGWRYIGGLPIVVPLVFLFFCRNDMVESPAWLLLCHRQNEAEAVLARLYGEENVALAIQWMKMSAAPNDTHKATWKSLFATRYRLQVTLAVHLPLSMQLCGMNAVSFYSSTIFKTAGIDDGRVGNLIIGIVFLVPSFIVPAMTNRFGNRKMLLGGKLAMLFAGTGLTIALVYKASTLSIVFIAIFGVSYMLTLCALSFPTGASVFPDAIRASGMSLMMLVNWLGTLFNGIAFPYIASALDDLAFLPFVVLIVYFLVFMYKYLPNTTGKTNEEIQQLFASESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT73</accession>
    <name>A0A8K1CT73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT73"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW68255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="36595" checksum="BEBF74240A485323" modified="2022-08-03" version="1">MAALEPIDVDAIIEKLLSVRGARPGKQVNLTEGEIRGLCLHSREVFLSQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPDANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIVDEKIFCMHGGLSPELSQMEQIKRFVRPTDVPDTGLLCDLLWSDPDKDIMGWGENDRGVSFTFGPDIVSQFLKRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKQRYAYNGLGAQRTATPPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTE2</accession>
    <name>A0A8K1CTE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the OST5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTE2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007915">
        <property type="entry name" value="TMEM258/Ost5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13636">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05251">
        <property type="entry name" value="Ost5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="72" mass="7983" checksum="B4D36751D8938C92" modified="2022-08-03" version="1">MEIPYSSPVDPEQYGTLTVVLLLAGLTVMSLFFTKAVSPQKNFFVEFALAVIAAFLLGFGSLFLFLWAEIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUQ4</accession>
    <name>A0A8K1CUQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUQ4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="102301" checksum="F22C375056A8F804" modified="2022-08-03" version="1">MSETSVVSVVTNQALLHRIASFQCGLPHALYEFWGQWYVYPRKCNQLRVLLFHLLDQDESLHRLFTRVRLTPTHVKAMGSLPLKKAVERGNARLLAWMLEYTKPKSQRELNLLWDFALRKFDGDFAVLQVLKSQLADGLASCSRVPLITDIRLFEWLCNSLDGFSIPPVVMESAVKRGDLAMIRFLRQHSADVGSRLDLYQEAWLNARYEVLAYLLENHPVPWRSDFARNIAESDLVELLKVMHEASARFERSDDLWPAGMMDTLATLGRLDMLRFLHEHRRGGCTKLAMDEAASRGFLDVVQFLHQNRREGCTTRAMNEAAGNGHVEVVKFLHKHRSEDCTTWAMDVAASNGHFEIVRFLHEHRAEGCTTQAMDNAARNGHFEIVQFLHEHRDEGCTTDAMDGAANGGYLAIVQFLHENRLEGFTSAGFEEALKSGKHDVVRFLASYQSTSCSPSMMTSLLLQGAFDTWLELRTGCDADDGVDEAMREAGRLVKPETVRFLCEVIGRRDLLHLAFEGAAQSAETDRSLIWLIKLNQFDSVSHCHFSEAVRALAFGSQSLNCLSFLLRICCDGSREEAIAFADDMMWGNDAPQLENLTSMEEEDFLAMVDPAVREPSTPDWALKTHVSARIHAPWFSLAIEKGDLPYLQQLHQLSLTSSHGDALAIKFEGTLKPAIQTGRLDIVQWLVEVVEVTLEPTLLETAVMNRKLDIADWLIDHYPDACKMFQSQVIPSSHRLPCPFGESDELVGWLQMNKKARDIVDFGVLSTYAAAYGHTHHLRALYDLDPEAVMDREDLIDVAAIYGHVSILSYLAEVGYTHWSTAAVDDAAAGGHVNVLRFLYKHHNDVRCSMDVSVTTREAMLFLLSHGYLDEHPSTFGYTDAPGHFRKDTGLVRIYRQYPDIFLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUV5</accession>
    <name>A0A8K1CUV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear migration protein nudC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nuclear distribution protein C homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUV5"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000001">
        <property type="entry name" value="Nuclear migration protein nudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025934">
        <property type="entry name" value="NudC_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14050">
        <property type="entry name" value="Nudc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="8">
        <location>
            <begin position="148"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="310" mass="35491" checksum="2B72C9984DB3E8B2" modified="2022-08-03" version="1">MSDDDRFDGLLLNMAQTQRGIEPLLDTVFSFLRRKTDFFSGATPQVIEETVLNAVRKQAALAEKDQFHKKQQEEEKRKLREKKLAEEALKKKQKTAVESKPAPRFEEVTDEQAEEIKSAAEKKDDKEPSPDKDGDEEDKEPAPVGNGGQTDKYVWTQTLQEAQVNFAVPDGTKSRQVSVDITASRLKVGLKGGETFVDGLLFKKVKVDDSFWTIEDGNRICVYLQKDNQMEWWKTIIQGDPEIDTQKVQPENSKLSDLDSDTRQTVEKMMFDQRQKQLGLPTSDEMQKQEILQKFMAQHPEMDFSKAKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUY9</accession>
    <name>A0A8K1CUY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUY9"/>
    <dbReference type="OrthoDB" id="270009at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000013">
        <property type="entry name" value="Blast:Protein SCO1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="118"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27667" checksum="FB52875865B67A8A" modified="2022-08-03" version="1">MMNMQRVRAPLRRALRSAAPARWQQRGFASVPKAGNDKMGPITWPSLALAGVIGAGAVYYYYVEKDRLQTQTTSKVVSIGKPLLGGPWTLVDCDTRRAVTNASFLGKYTLLYFGFTHCPDICPNELVRIGDVLDKLSKEKDAPEIIPLFVTVDPNRDTIEQMLEYKKDFHPSFKMLTGTRDQVADITKAYRVYFSKADENEDDDDDYLVDHSIVMYLVGPDGEFLDFFTQSARVDDIATKIKSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVS5</accession>
    <name>A0A8K1CVS5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVS5"/>
    <dbReference type="OrthoDB" id="167248at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="509" mass="57791" checksum="890C2569C3F0D9D9" modified="2022-08-03" version="1">MRLSWRCLVDGFSACGIRGVYFDEGFLIRELIEIGIQTYQAYRISYLVPQGWVSQLAVCVVVLNCWTTPLLHFAFVFFASNHDRHEPLRRVLCLATDIVLDFFSSMIIPFLIYSSYRSQILKNRWHDPLWALRVGNDLLCFYLSNVWDVGFRLLPNFSMLTCLGAIQPLFRPRGIPRSHPSFRNQFQVRRSHQPSSRLWVVHGFLAVYGFAILIISSAAYRKVHQFSLVGCHSTTRSWFATKYPCAVLELNCFRHNWTGSANELDSTLELADERTIAAVVITHCRQLEMPSQIQKFKNLVWLEVFNSTIAQWHDDAALSSFHHHRISRLMLIHVNVSMFPTRALADEFPPTLIDLEFVHTNLSLVFPSAPGRSWPSSIYRLYLEYCGLVETPPVLTSLRVATLSLAGNALQSFPSTLVDNRRYRQLSLAQNPIQSLPNAVWAVTTLHLEGTLVSSLPPSLMNSSTTTTILATQTPLCSMPPPIPQLDCALSTPDGAFFPLELYQVGRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVW9</accession>
    <name>A0A8K1CVW9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVW9"/>
    <dbReference type="OrthoDB" id="123356at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="36334" checksum="908B297C244AEC2E" modified="2022-08-03" version="1">MQSQLSGRASFATSDDTIGGPNVTTIVPNRVSSVPTVMATRIKGRGRLVAFLSLNAGFAYLHLSAALTLTHQWQLFLYAAFSLALKITIQEATKKYQLHAARMPSARIVHLAMSIPTLTIDAQIRMVIVQKSMHSSMQATSIVQGSAFTVLLCEVIFRLVKIYRLRYVVRSRFTKSKGMKRIMHRVNSKIAARDVTVARAEYAQFLNWKNYMLRMHAAEVYADMHGEYISVGMASAIVYFMHQHPCYRIGAEGESVERQMLGALFQIGTGLVFDYISSVFEGVHEVPLYESISDEGKGLRTFMHVLLGALTAGNVGVVVTFALQQCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBK0</accession>
    <name>A0A8K1FBK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBK0"/>
    <dbReference type="OrthoDB" id="125539at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000006">
        <property type="entry name" value="Dual specificity protein phosphatase CDC14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="284"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="59056" checksum="1A5E5BB1B04EFCF5" modified="2022-08-03" version="1">MKRRSAVTTRPIEFFPRRFYLLLLRETPSYGGSSPASSSQLVFPRTPGIEFVALEDATWRAQSLDVANTLRFCRFLDRLRHQIPPSSPTMAQKAPQLHFYVRNLHLEAEMALIHLIARWRLLCLRLSPREALAPFQHLESIARPSMPLQMSLAGISKGVSTELLFTSATVEHQSQEEQESPDHDSAHMTHITKRFLIFAGPIDDIPPPTADSSASEQSEPPPATDPRPRLSVAQLVPVLKQNRVAMVVRLNATPTYDDQLIIRSGIEHLDLSSTDDTFDAASVARFLESCENAQGVVAVHSASGTGRAAFCVACFLVKHAQFTAAEAIGWIRFCRPGSIPRGYELLLTQMQASLWRDGDEYRRTMPENASPLTGMKEDATSNTRLTTHISIGKIALGRDSLLGTKEKTKEKENTPKTTARLIVQRSSGSYKDIPPTQELVATTEASLVRRRPLTQGALGRRRLIDRTSDGGSLRADFATMHKFLHQSSGGNGSATSRLNGYGSNRSDIDDVVIPPRPTATAPNRTRTSKVEITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBM4</accession>
    <name>A0A8K1FBM4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kringle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBM4"/>
    <dbReference type="OrthoDB" id="444255at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052613">
        <property type="entry name" value="LicD_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13627">
        <property type="entry name" value="FUKUTIN RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13627:SF33">
        <property type="entry name" value="LICD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035466593" description="Kringle domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="40915" checksum="8B910E93557C643B" modified="2022-08-03" version="1">MVVASVLLLLRTLSSSEVLTSERANLSRYPAFYTEERVYHDAGCSPKTLDARVVEYPSNHRFYHLLQSLDPPFTSPVFYGRHAHLCDPHGTECGDRGWSYCLPITARREPEYCRGADRMELLVPQSTDTLCYGSVLHMLLVDVYAVFKEHATQPAVLFGSLLGAVRNGSMIPFTEDADIGYRYSDDVNLHAIKYALWHKGYHLFRQNILRVCVAPTHPLASNLYDRYKAIDGRMCHVPYVDVYQMERAENLMEWHVEEIKNKRRVPNIKFEPYSQVTINGIEFDTVADPVDFLEQEYGKEWRVPRRRGLPSPKDENARIPPPWMDSELFESDEEEIGLPDIQVPDLEEASDENER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD7</accession>
    <name>A0A8K1FDD7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD7"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="34997" checksum="FE21B02F655848DC" modified="2022-08-03" version="1">MATPATHPTTTGGSETHVPSPVLMEPPGAGVSTRKLDGRGLKIAIVSTRWYEKEVTHPLVESCKNELLAKGVESANIKCFQVPGAYELPFAASRVIHTKQQHMDCVICIGCMVKGGTMAYEFVSEAVTTGLMKLNVMTATPVVLGLLTCTSEEQAKACASNVCVEGHSGKKKCNYGVEWAQEAIELAHLKRSTSELIEKKRVSHCKQEGCSCSCHCQQCKCHTCSCEGECKCSSCEGQHKAQKKQTPLTQAFDEALAKCSGCGSESAKCNCKGCNCASCAHKQEQQQGELECGGCGHQKKSCTCTTSHTKTGVTTTRHQPAESSAPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDQ9</accession>
    <name>A0A8K1FDQ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_008495</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDQ9"/>
    <dbReference type="OrthoDB" id="433501at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000026">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003603">
        <property type="entry name" value="U2A'_phosphoprotein32A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00446">
        <property type="entry name" value="LRRcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="4 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="16">
        <location>
            <begin position="71"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="15">
        <location>
            <begin position="621"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="519"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="532"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW55847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="72166" checksum="886D6F46EB30D932" modified="2022-08-03" version="1">MTTIHVKLHGAPSAALSNATDVYLLEEEHQVRLEENLIVAIGAFVFFWAVFAASWIISTKRVPEFSSFTPAQKADWCSRINSTIHAVAVVVGVVVALVCIEWGDDFMPMTSLRTASITFSIAIGYFTCDLIVIMVWPVPLQSVFVIHHTVAVVPYAINNFVACCAACQFGLLLFLLVELATLPLNARGFLESVGREDSKNHKRAIYATYIVWAFSRTVLPVFLVYSFWAYSYPSKRNHDVCLYPNLVGAHVIALFCVGVFFFVHTPEMLSIRRDRNLLPANNADVASTQVALPTPPMSVKEAKKLKHLASGSYEEVEPNGMSTPPVLAVGDSKRGGSDRPGGTMRLTVEVILRAQISINPLKDRELSLRGYQAPAIENLGVTKDGFDCIDLSDNEIKKLENFPRLRRLRMLLLNNNHIAKIQDNLADSIESLQYLILTGNRIADFSEVDRLVAFEKLDTLSLIGNPVTKRKYYRQYVIHKLPQLRVLDFQKIKPRERDAAAVFFNSVAGKRVEQEAEFESNGAVPPVTASVVPPPPPPAAAQPPPAAPKQVPPPAPAPPKPVPTPAPPAAKSQPADVEMAEPPSPVKKKKADPAPAPSTPPKPAKADVAMEEVPFTPSKPIEQLTVNQLREALKERGLATKGLKAELVKRLKEAVGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDU8</accession>
    <name>A0A8K1FDU8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDU8"/>
    <dbReference type="OrthoDB" id="123467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF14">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="22785" checksum="E76E19D06B3D4D91" modified="2022-08-03" version="1">MDSSLFTTSLSLAELSILNEIQRMLTPDIQDVRARLYKLNVYGPGGFFKAHRDTPRAAQMFGTLVNLDELEHASSVKANAKGSTKSTHSVAPAGQHASESKQAESTPAMTTSLAEKLQEALRDPEFAPNGVKLGFALCHGYIIGKNGKVPVLKGSDHLLKDDLDDLVSKSRKRTYWGLDVQDEAKLQQLKEWEFEDMVVPERDGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEC7</accession>
    <name>A0A8K1FEC7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEC7"/>
    <dbReference type="OrthoDB" id="98240at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="39553" checksum="84942E680FE28342" modified="2022-08-03" version="1">MASMADVKIPPDWLRSPNFAKRSELYEARKAEMKQLALDKTPMSPYFDQKFARTESIFRDSYRKSGAYEAYASPVSPNPRDFHPRAIASGIPTRSVLLDQRAEQKRLESLKFEPQELLRLADIPKPGAPEFEQWWTKVEGYVADPSPMIEDSLRIALNGNPHAQRGRFRLGPVDPAKERSPASVEARQELKHVKAQLADKITRLNHSAPDDHQGQNRSENAIIFRASDLYAQERKRASSGEGSRSETLLLPVSPIKPTKLCSPKRSQRHMENFFLECTNQRALLDQFKTHSPSSSPIHSPSPPRSVARSEVLRLPGMHERSHPTLEPVEEFKSPHAVKGYRSAIRCGGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEI3</accession>
    <name>A0A8K1FEI3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEI3"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="233"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="426"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="779"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="904" mass="99435" checksum="8D76A16C22157E1B" modified="2022-08-03" version="1">MGGKVLAEERARIVQNDSLSHAPPRRGPSLKLEINRPAESVQLEDEEEDGDDNDKRPILGSNVYLDSPRVGRVDDDVSPQEIKRRRLIGIATLAGLFLSIMLCVVFLHYLSHHESFGVLPPTQQRFMFSTTTGGARESLEQYTAGVRHTGSPGDQEMAKYIRSKALDFGIEEKYVKLEEFEILVNEPETLKIEIQYNKTAPVVIDKMTKFSTKKTTRMPYPAFHLYSKNGSASGPLVYAHYGRSEDYAALEEAGVNVEGAIVLVRMGEISLPAKVVIAGREGAAGIITYNDPSDSGYTRGKTYPDGPWHATDEASFGSVYMGNGDPSTPDGFSASTVDRISVEDVFSPHNTYNILPPIISMPVSAQSASELLKALGNETNVTAKTAPQVFANWTGGALNGTYRIGRSKVNIQMETKNKYSLKKVWNVLVTIPGSREADRYVIVGAPRDSLNAGAVSPGSGNAVFIELLRAIGDLLTNGWMPHRTLLLASFDGEQFGSVGSSEWIDRHFSHLGGRGIVYLNLKDVVRGAGALHCEAAASLRKNVYLMSTEVVQPKIEVDVSKFFSSAKTLSIDENDVDDSEDKGETDPVNTENGRRILTETSADGSILRTIVETPSPAAGFIEGEDEEDDESSLLPLNTTFGHEDLKDSGDSIYSYWLGATKKRHPKATLPKIHLPGSDDRISPFLARLGIPSVELGFDGGYFGVEASRNDSMDWIKRFADPSFTFHRAAAQLYGSIMLSFSDSIFLQYDFTEVARDLRHGESYLQEALRRTGLTGALPMSRLASSIAEFETAALGVIKEIRDLRDSMVNMISGELVVDLKKVREMNTRLLMTEKAFLLPSGLPHMPWLKHALYGISEYNDYRVGYYPGVAQEIKRGNAVTMKRELIRLCQTIEQAADILSTPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEN8</accession>
    <name>A0A8K1FEN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEN8"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452651" description="Glucanase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="48864" checksum="A72814ED0090A2C0" modified="2022-08-03" version="1">MRTACQLLAAAFAAHASSATAYGALDCKSSLTGSYAQAVQTYPHLKNAISMVASQSIGVWYTDRQTNTAESTRSFFLPKCEGSVNQASQNQGIASQRPTIVVYGLPQKDCEHGFSTAGSNKNSDDYRAFLNLLAEASQNQPVIYILEPDAIGLLAKNGCGNSNNYAANLALALDVLGANPNADIYLDIGYWTVMSDDGAAEVAEVVKKVDTSGRCKGIALDTSNYRSVKEMATSCERFARVSGKNYHCIVDTSRNYVPPASNEWCNAKNTGIGQLPTANTGHDLIDHFVWVKPPGESDGECSGQTSDSLPGPSAGSFFTEHFVQLWNNGVFVQELGQAPLSVNPGVQDVVVNVTDSASNTTPPSVVSEATQQVPVTVNSSDRDDFFTTSDVVSDSNESSPSDTPTPVAQDREYDDSVEGPSVHVEYPVETQEPSYQDGLETSDYTTPTEAPKHKACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FES1</accession>
    <name>A0A8K1FES1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000897</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FES1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="3"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="42942" checksum="AF2C9672FAD540FB" modified="2022-08-03" version="1">MPRIVIIGAGPAGIIASNTFAKSLKPSDKTEVVILEKNKYYYNTVGAPRAYTDEKYMPNMFIPYDKAIPKEASSFIKIIRGVATAITTDEVVYHKVGNDDKPQDAASTLAFDYLLIATGSSYTTPIKQDVNDYSRSGTEAQLKEVRDQIIKAKKILVVGGGSVGCEIAGDIAAHFPEKKVTIIDGHDRLLSANNLLEKFFTKLTNSLNELKIDVILGETLEERLTENRFEKRVLRTSKGREIESDIQLLCAGFSPVAELVQNLDASLVDSKGAVRVNPHLQLDSMNYHHIFAIGDVNNSSAPKLAYWAGEQAKYVVNKIVGLIRKTQTTVTKPFPNVGLEVLFLPLGPNGGVIQLPFFGGLVFGNFLTRMFKSKDMLAGRIWANFGATAPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF33</accession>
    <name>A0A8K1FF33_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF33"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="7">
        <location>
            <begin position="120"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="40172" checksum="9F3C15A77A3B4251" modified="2022-08-03" version="1">MTLFQVRRMQPAALTAAKAFAKGPRMALQGRTLRFDAKMASMQVMMPIHSFGSRSFSSSPVPSLFDEDKIVAMSPAEAATEALDVAGSVDPAAVANLGYSLSDLAIRALEAVHITTGLPWWATIVATTFAIRTALLPLTIKSLRNADRMKAFQPEMDKLRDEMDAMPQKDPESMAQFRKKYQALMAKHHVNPLVGVLTPFSQIPVFLGFFWGLQNIAQYFPDYSTGGDFWFPDLSVADPTYALPVISSALMIASVEMGADAMPENWGEKARFGMRLFGLVMIPLTMNFSSGVLVYWVSSNTFTLVQSTAFRIPFIRSLAGLKPTAPKVQLVAATGATSPFQAAVQRAKEGAAINTHMHKPKKSAAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF83</accession>
    <name>A0A8K1FF83_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF83"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463711" description="Glucanase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="45892" checksum="7832B9163B4DDD40" modified="2022-08-03" version="1">MRLSSAVSLVSASLALTSVSFVASAEEVMPICNVWKGYTYEKAKADYPDLTDSINIVQQHGFVPWYTDNSPQQGLDVIIEALQSKCPEKSKIPMVIYGLPKKDCVANYSNMGFNKNLDDYKAFLQRLNDAFPKQHMIYIVEPDAIGLTVNGGCSVDNDYKGAVKVALEMLSANPNAELYLDIGFWALLDSGKPDMLAQIVNEIWPKDGGKLKGIALNVSNYEKTEEMIALCEKFAKLTGRNGMKCIIDTSRNYRGPSATHEWCNAKGAGIGHPPTMDTGNAQAAYFLWVKTPGESDGECTNEKSGEATVGPRAGDFFKDYFQMLWQNGYFVDKKQTSPSSAPAPTTAKPTSAPAPAPVVTLGTETPAPAPAPVVTVATVAPAPVPSSGSGSFLYCGPARPDAASLTAWCNQNCPAFCPTDMCKQGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFD9</accession>
    <name>A0A8K1FFD9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="163928at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056536">
        <property type="entry name" value="TPR_NUP160_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056535">
        <property type="entry name" value="TPR_NUP160_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23354">
        <property type="entry name" value="TPR_NUP160_120_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23347">
        <property type="entry name" value="TPR_Nup160_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="5">
        <location>
            <begin position="73"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 middle TPR" evidence="7">
        <location>
            <begin position="1133"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 C-terminal TPR" evidence="6">
        <location>
            <begin position="1282"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="741"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1552" mass="171326" checksum="45D2941AEA7318F6" modified="2022-08-03" version="1">MTVQEATFACFEDDESELGVAHGVFQARLLPTHAIAAPVGFQTLPSRSGSRLHTLESTGSGTFFFQNDALKHRFLCWRIVKNTVIFRESSLHETLHQNAIRLKFPAPVVTKGGVAAFEAWDAHAVVLSVLTHAGTIHRLTFAVPVAAKSTASTGAASIFANEETLALAASTSSVFPRKPAFHVATTVVNSLQADEAITTALWVNEYNLIVSTDSGRIIGVNFGLPSAPEQTPQEFLFSDESMVRWIWNGLVKTSGVRRRTGNGDDLAGLSRDAIIAMTFFPLDNSNSENEEDEDDNGEIEDVCVLTLSADFTLRAWSFRSQVCLGKQSIRYLVRASEEDDNMSNDDDDDSEAFATQAKLMAIPSSTSGASRILVHVDSTDEYPQQLVLLRGDISTSGTHDDLGLEVSRVFSVGQGNRLKFVDFAIEKGFLYSAWRSTSGDFVYSHENPMALTGPRLIAGQLIGSGDVQMKKYEAEDLELPVQLGEQGVEGAIDNFYAERVLLPGRFSRHSLYKAISELHSGVDAPVRAYFTQAGPQESRFKELLVNVVSDKWLQSAGKQHPRWSVHDAQQARVEIWKSIVALCTKHWRNEVAPIGFAVAPSTLTLGSPVLLRRNRLSLFFPSAASIVSNMLTKTVGSNRDHVRDIVADVLPAYDAFPSHSFQSSIQNEVSVMSSDWKVESLIALARQSVRLSMRAEPSIAGVQRPDLVLTRALLRLSRILGEGDAHVQVLQDLVDGLAPSDPATSAEDPFASENSNGVMDDDEDDQMNGETNTRGQYFGGNEISFAFSQASARTVDELCAQSLRVVLCLAHLVDAMPTFMTSTTLKAVERTILPKAIIVYQRWSLSRWFANQNISSTTELDIVTAKAFGTVLPPLLQSFLVETSASLNHVETFQRARAVAEMRDLDPYESEDPHKLLASYIGGILELVSRPNDRLVTFLQKKKEFSILRSMLSCTLTDLSLQDADGQAQATMHKYIRSIGECLAWEGHQAARNDAKEEAAWCLKQSIRCFNMCLSSFCAQVESSQNDDAMEVCEQFISDSVSLLKETVPAGFYDLTLSFLWVIASEALKLVSSKSLQSFVWVNIFKYSVEEHQYHDAHLALMRTVSLSSLAAPSFDEDGNAHDEEAAAISRTAVECTSYFVKELCRHGRLDLICDFQWGVLESEVEEQIQWLAANANVLKDGCVDPTLVMFHQLVYAFFVRRNQPANAAAGMHNLFLRLRFAPTKSAVSLKTQRNALMAAFNILMKLDEENRWVVRKLNPEDVASGKLSAKQVASLSIVTYKDIERDLAVLDGKLHLLELGQEESLLLSSMGAPEIVALLIDSALSRGEVERPGTASEKQQESLVLLELAVQIASKASLGYEQITRSIARYCVSNVSKIGIDSLAWELLKTYLRFVDELEQYEIAAETILSWRVKVVLPEWITRRLTCPRTGNASKLVLRYLQHGLLIEASTVAAAMIPMDVLNEDETQFRKRASSSSMPLPFLPYNLFDAVLNASDAALSTRGFAADPGDTALRSATQKLRDHLVKYFRYVDTLQQARGAANASKNASNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGJ3</accession>
    <name>A0A8K1FGJ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGJ3"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="723" mass="78666" checksum="A43526B04B5763AD" modified="2022-08-03" version="1">MTFSPAGADHFEKSTPLATKYEDGSHKKRCSPLVIGNTCLGIGAFLVIFGIVYGAALPSVITNQIESGVAVCSESDIAKEQFTDNYGDCDECVPYYYSLIMFNVTNANDYLKNGAKLKVQEVGPYAYRRFQRKVDVKLEGDLVSYKMYTYHKFDAEKSCETCKDTDVVTSWDLSYLNVISQAGGEKGFVTRLAKGTTWGAELSDDEIADVVEKNGEQMMRWVNGLNSNQPKAWKAIGETVLPFLAGGVAPIEDLDLSGFEYNGLFAQRQVKDYALGFPSLLAGLGLGTNYVKVCSSTSTTKLEEKCASCKGDACDKIWSECKKCVTGKKVLAINAVTCASIEARYAAVYGEKEAKAFSGSTCGLCESVGLCAAPLPGAAEASGLDYSEKAPSSDSLNTYIQRTGCDDKTHINDYIQYDGFKTQPYWVKLDKRRNPTLTELNAFAVYGNCEKRTSNMTCSDVMGTDATSIEPAGASITGFPSKVDLQEAMMYLNQAKQNISLVNTGEVVEYEGIKLTRFIPPNDLLQHADWKDAKGTGYPVDGVQPLAFNVGFLAYLSYPMFIYGDKSLMEGVEITMADGVKASQDTLFEDGVLKEAYYNRYQTTVDIEPGTGKTMVARKRLMASYALGKSSFSDGVMSDLVWPKLKAEVISPAYFGEESATITPSRISTYKGVKAILTSLLPVMIIGIVLGVALVAGGFLYRRKAQMTRRDTMGDAILGSSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGW5</accession>
    <name>A0A8K1FGW5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Temptin Cys/Cys disulfide domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGW5"/>
    <dbReference type="OrthoDB" id="108313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057626">
        <property type="entry name" value="S-S_Temptin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055313">
        <property type="entry name" value="Temptin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34737:SF2">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24784">
        <property type="entry name" value="Temptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419242" description="Temptin Cys/Cys disulfide domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Temptin Cys/Cys disulfide" evidence="3">
        <location>
            <begin position="21"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="22420" checksum="C66DE9A33A7D7927" modified="2022-08-03" version="1">MKAFTVFAATIALAYTLLEAVNAMPSYLEKLPNGKSFTQDLGHVDGTSSGKFTEFGIMFQKASYKWDAVCKEKFPGTDITVGAAFGDACCVWTGEGDAPEQLAEKWTTKPTKGTTCATAPTTAPSTAPTTAPTTAPTTAPTTNPTPAVTPAPSAEAEESPSPASSQPGSGKCRTKEDGDNGDHKQGPSKPGKPGNGFPGKHNATKSYDDDDGDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW2</accession>
    <name>A0A8K1FHW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012957</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW2"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000146">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1470.10">
        <property type="entry name" value="Photosystem I PsaD, reaction center subunit II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="598"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="978"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="199"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="436"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="693"/>
            <end position="700"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1000" mass="111743" checksum="6EBC45E444F452EB" modified="2022-08-03" version="1">MEATDPELFQAGVMEHARQLGIDPEAEPDLLWIARDSLVAPLPDGWFHGTATESGAPYYYNEVSGESRWDHPCDDYFRRVVQEARQKQYSATGAQAASYYGKGSTAYFNGGSAAWQEATGDASHHEYYANVQWAAGQPVVSDTALDAYYQGYDAGGYNKEYEEADEYDAESHSTMITPGRRQHVRGARNGADSPARAELEELTRKVKHGDDRIRQFELEKDRDEKELSELRREIKLLNEQIESDHQQHKIALESAMANLERTESDRKADLERMEKQLDDLAEENTTLKQEMTDVMRRLHGDAANEERNEKEIEELREALDQERSVRKKTEEDIQLLLEEKTQLAKELQSAGSLVRKLEGDLVRHERSERQETEAAAASTASAVAAAAAAEATIAAMKKELTDREVEFAATQDALTASKEEIDVLKLKHETAILAVEKEFNERLALYEKDLETQQRECFVLNDRLRSMNEEKIASEKKAEDQSKIASVQLADAEDKERTLKREIRALERELKSLQTVSKEREEEFIATKRVVERLEAKVQEQDAIVEAARRTAFEEAERMAAEQVRQAQAEKAKVAELYAHELQTRRKLHNRLMELQGNIRVFCRVRPIQAVELKSEQSSPAVFFRDNDAASLDLIVGGEAGPDGKLTSIGQKHAFEFDHIFQPASTQEEVFEQTRALVTSALDGFNVCIFAYGQTGSGKTHTMEGPDSDRGVNYRSLEELFHIRDDRNIAGNFDCSMKLSILEVYNETIVDLLDNTTPTGNGERKGLEIRMGKQGVYVDNLIEVEVFNLKDVMDLMKLGKSHRSVGAHDFNEHSSRSHLVLSITIESGQKGESKRRVSKLHLIDLAGSERVSKTAASGQRLKEAQNINRSLSALGDVIAALGANSKHVPYRNSKLTFLLQESLSGNSKVLMFVNVSPVQWNAWETLCSLNFASRCRNVALGLAKANTSANASSPSPSNGAKENHNASFSTVTAGTRATVNATGMPPRGPPSTGKQRVVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIG7</accession>
    <name>A0A8K1FIG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIG7"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="229"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="381"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="55875" checksum="D75926B8B94170E9" modified="2022-08-03" version="1">MLELNRCTADLERGCTVHKLHRDRVLKLRSRFEMRKPHDKVTARFSGHSAARNRAASMTGPEKIHLINSIVESEVVNYLFEIPFLEGVDDSRLVTLSNLCSYMFIRRDEVLCKEGEIGDCFFHLHPRKSPGVSTRHPATETQSTHRNNRRAQVAGRQASRVRLILWRNLAALQDPGICSITALEDSLLVYIDRVAFCNFLKIVPKSSLVLLEHVRLHFLDTLIKQGCRFLNAFPHLKLQELSFISELVERQEGETILRREEKFPGFYILLRGQVQLEYFAITNSKRDDEQSDAPQTENASSAGTKATTAVPPKEIVTVGPGGYFGQEAIILGISSPIRVKCLDHCLLLRLTNEGFAEFFSSLPVVYSEFCIKCLRDRVRPEHVMQHYEAHKLWAADCVTRRRNQEIALFEQIEDFKWEADLAEERIHERALVVYFRFLAQNAPNCVRVSPKSIQQIESELSSHMISRDIFQSVRNEILELMEDDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIW2</accession>
    <name>A0A8K1FIW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIW2"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467368" description="Copper transport protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="389"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="464" mass="50634" checksum="146CFF50C021E814" modified="2022-08-03" version="1">MMLKMRVMLWTTALTALVMGGGARRVAAHGMHAMHAMEEMADVSSSDYKCPVCRMSTKTMYNNENWVEMANGQRVYTCGMEPRQFDDYDFKSTDTAYLGANMAEFIVNESDKENYACDASCPECATGIKDPISGAAVTTDNFKFVCLANGQKIYFASADTRKEYLSKVNQTPRVAVSAMTCEKNNCSDATKIQTLSALAKAFKPDTTSSNATTPAPASSSNSSTTTAPSTGANTNAEEEGNSGFCSGEGSVMFNGFSSTVNGSCVMLFFKPWVLNSALKYVFGFLGCLGLSFGNEYLVKFREQMRKKLLAARKERPLDKMHRLQCKLLLSLMYMIQMTVAYFAMLVVMTYETGLFIALILGFGAGFIFFKEFDVDVTNERGVWRYTDPSVVRLQVDGMSCMKNCGTTVENALLAVPGVSNAMVDFDERSAYVTGVVSIETLIQAVEAVGFSARSDSATTPSSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIW7</accession>
    <name>A0A8K1FIW7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIW7"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="21348" checksum="E7FA26E9E584301C" modified="2022-08-03" version="1">MTNIVIVYYSTFGHVVKFAVTIREGINKVEGVTATIYHIPETLSDDILSKMHAPPKVSYPIATPAVLKDADGIIFGFPTRFGSLPAQIRAFFDSTGGLWAAPGLESKPVGLFCSIGALGGGQETNAMTALPFFTNHGMMFVPLGYRSRLLSNLEEIHGGSPWGCSTIAGPDGSRTPSELELEIARVQGESFAEVTKKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ66</accession>
    <name>A0A8K1FJ66_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005422</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ66"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="58773" checksum="CEB786B115DA0538" modified="2022-08-03" version="1">MDDHSTLMASSRSPRSDDAHDDGATACPYVVLHDAATDQKVRPLSASTSLWTPSTLAIPVTYLCVGFLLSFPRAYIEFFPRTRNASDAQLSTVLVVRSLPWSIKVLFGILPDNFPIKELRFKPYILLGYALSSVFHWLLARAGESELTVVSFTMLLLGAMVGIVLADVMSDALVASRVLRKEEAYPGHTQSTVYVCRGFSEMLGYWCGAFLSNRAEWAFGLTMSEVFLLLAVLPLVTVVPCIYLLEEPHVTHVATWSQQREQLWLMLQRRATWQPLCFLALFNAFLLHNSAWGNYLSVAYRFNAFEYGAMSAISASVTLLALLLYRACIHPNSTSQPSWHHVYFITGILISLFSILNILLVFKINDAMGIPAFWFAVGDSAVISFAKGFQQLPLAIMLVSACPENQEGIAYALLSSITNLAHAFAHTISNMLLRIWPVELVDLRRGDYSGVWKLTVLTSVIALAPLFWTKTLLPRGKAEQDAMRNELSVKGARVVLALYVFGFFWVLALSVLAIVEPCNVFVGGHGCPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJJ5</accession>
    <name>A0A8K1FJJ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJJ5"/>
    <dbReference type="OrthoDB" id="125527at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="239" mass="27192" checksum="870E3B6652599956" modified="2022-08-03" version="1">MVGSSMRRLFSRGTDADKTTAPQAQPARSLSDPTSAATGPSQAWDGKCKRCRKLMSQCLCHEDQQQMGNRERTPSIEYSFPPSEKRHLFETLSEMHSSRTHSRLPIKMTQDRSRDRRLKDGEFHSARSAPSMSCAEPPSDKFSRSYPDAKWRSSTAIKSTVRLAHAPSTIPARRESSTKNLLSYESKKPTNRFNHVGMAPVVPGPQVPSQNYYVERPIRRRSREDEPNNEEVSEQIWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK87</accession>
    <name>A0A8K1FK87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK87"/>
    <dbReference type="OrthoDB" id="2155027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="187" mass="21455" checksum="4D2426F1C42F341F" modified="2022-08-03" version="1">MNAQYESDTLPSMSEFVLRVATPADAEALSALATRTCHDTYGHLPAEDLQMVLTTAFTVDNMRKEIENPLIYTVLLFSKDDETTPCGYGMVHDHRIRIGDNDSAENYIELKRLYLDKSFHGQGAAGILMIHLMDYLREKQRKVVWLGVWENNFRAQKFYQKYGFEETGEYAIPIGTTEDRALLYTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKB8</accession>
    <name>A0A8K1FKB8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003646</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKB8"/>
    <dbReference type="OrthoDB" id="69593at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="161"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="653" mass="73860" checksum="C5C0AB57A8819BA1" modified="2022-08-03" version="1">MLRPTVTAMARAWRVHSTSRVSPWTLQFAAFASQDAVRPNRALSTASSHRKRPTTSPFGHQRHDKSGVTAQLQQLLSNASSQRNFEPDVDFLRQAATALQAVHTPAQLQAARPLCKLVERASTMQASAVGECVRVYEALGEHKHAIELAFRLLENDFFLMNSSLASALQACTARKELVEGFQLFEMALDRGTIPNRTVFSALFVLCGATGEHPLNSPRVQRTLEKMRESEVEMNHTLVHHWMISYAKSGHFDHVQTLFEAMESVVQLRPIENTYAILMDAYAVRGAYDQVMALLETLKKSDELKAALLHYNVALKACGKASELTNAFHLYEEMKDKEIKPDLVTYITMMHAVYHGELGVIDTKKVKAALAGVGAMSLAFVPFIDFEEHWLTALFCGSLVSSMGLAVYMNPDGALRALYPNSDEPQNDTIIEAFFRRLREEDHCGRSMYLWREMTKHGVAADSRVYDVLVRTCVKKRHPELAYEALFEQNLPLIDSESGQFVLPQASTISLLHSLLSQRRLPMADTLFDAARSNRVFQELFQERKDQYTYDLRPFNTVQTRSYAMRRILTQFHEEAKMFAGKNSSNLPDVQFLLLHGYDLLDQLDSEAPQLRALFSMDEMKKEPSGTQYYFRLNVSKARLAEFLANPVVTNTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE5</accession>
    <name>A0A8K1FKE5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">malate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010711</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE5"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000010">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000002">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003916">
        <property type="entry name" value="PRK05442.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="155"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="346" mass="37594" checksum="27A39FA29088EC11" modified="2022-08-03" version="1">MSTIKVVVSGAAGQIAYSLLPLICNGLVFGAERRVELRLLDIPMAAEALEGVKMELQDCAYNLVDAVIPTSDLEVAFKDADVAILVGGFPRKQGMERKDLIEKNVTIFKAQGQAIERFASRDIKVLVVANPANTNCLIAMENAPSIPRKNFSALTRLDHERLRSFLVERVNAGFSTQSVTTRITSKDVRRCIIWGNHSSTQVPDCTNVEVTVDGKTQPLSTFVNDKAWIEDQLVKDVQQRGAAVIKARKLSSAMSAAAAIGAHLRDWLGGSVQGEYVSMAIPSAGNKYGVPEGLIYSFPVKCLGNGEYEVVNGLPIDERTKAMMEATAQELTEEKNDAVEILARVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKY4</accession>
    <name>A0A8K1FKY4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKY4"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="28"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="250" mass="27326" checksum="7286CE82861B1A2D" modified="2022-08-03" version="1">MVSTTTELSIVFATIAAGVIFTGQTLQTGEFYKPSSMITSSREDSMAPFRRSPCPAVNTLANHGYLPRDGKNISKVMIREAMAEVFNLDPAFADTLLTSVPVDVFDLNLLGKHGLVEHDVSLVHPDSYYGWDPMTVDGNLAKNLLSQAPYVYGVEELGEFRRERYVYCITTTPNCTFGERESFLAFGESALLLDVLGGNRNSTITKPHLASFMVDERIPSDFVKSPVPVAFDQVIATSKKVAAIAMAPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLA8</accession>
    <name>A0A8K1FLA8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLA8"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035473316" description="Copper transport protein" evidence="6">
        <location>
            <begin position="25"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="36196" checksum="646624568375281C" modified="2022-08-03" version="1">MTSRRGAMLAVMLLLVASLALTDAGQNLRKTTCPLCDMDIRPEIKAPILGNQFVYACEMAGHIDQLQNEPKSNLGAPKQVDISKDVVYKDATDISCPVCGKGFSELKYAVPWISLGDQKIYTCSEEHAHEVFANPTKFIGSGETVGGFCNQGSALVPRGSVMFNGFQLAIGKEATCALLLFKPWILTSAVKYAFAFLGVVLLAMSMEGLGVFRDSVEERLYRQYGVVYSSADYHEVKSPSSGTSLKAVESTALNAKGVMMMRRIPFWCKVVLACFYMVNLTIAYWLMLIIMMFETLFFVAVILGLGLGFFIFKDTEADKMSGNIDPCCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC8</accession>
    <name>A0A8K1FLC8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="122" mass="13508" checksum="8654D238DB41AB3A" modified="2022-08-03" version="1">MIITVDDRDVAQDRESQIHQSTELASTAPCLPEVMQRMATAGEERHAIQLLVGHCDFSSRVHVDGHWAHELPCPVTSSADLTTRSNADGCIVLYLHIKATQSAFKCAVRILFDIYELDFAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLE6</accession>
    <name>A0A8K1FLE6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLE6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="31606" checksum="428881533B015229" modified="2022-08-03" version="1">MTVNDQILDADAAKQQAVDNLVNSLSEHLLAFQQQELDPAKVEAQLRALNDYANIGDTTSGQVLPADDANTQDGRVRLPRVAAEAEETERRRFLANEEERRRRMAEEGDKLKNPLARKREADGKPRPPELLTDEDDRKQPPNTWRKLADEADRRRRWMADEADKRRWLADDADKNHKRWLADEADKNHKRWLADEADKNHKRWLADENAVVHSAAKTAKAQNFLAAGGDRNDAVMGLPQIFGGAFILVAVIALAVFTGGRRKKTQVEDKDDAHYQLYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM84</accession>
    <name>A0A8K1FM84_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM84"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="90"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="17055" checksum="D540D78A9102E0CF" modified="2022-08-03" version="1">MHHVRALRVSSVSRWRVPLASRRRALCSSRKGEESISASSALRQQLEFCCLVCGWDVPCTTCPFKWYGFDGKTRYRVSRDAASTPLRVAAAIQILHVPLDSGANMTRQTLKEAFRRQALQWHPDCNKDPDAETRFKAILDAYEYLLALTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMZ7</accession>
    <name>A0A8K1FMZ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMZ7"/>
    <dbReference type="OrthoDB" id="97510at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="48376" checksum="E9FE4C89F5606F4A" modified="2022-08-03" version="1">MAGIQEGAAELMELFQLPGEPATFINGDDDEHHEHKLSAEDKLAMLPLPGPDTDLDGKARNRLIVRRYYYRKLTNLNELRAEVERLEDRYQQLLREEQAMAARPSAMGEQSHQTRRQETHAAYVELARLSDALRRENEELLRTTSDYEKMERQLSTLYISQCKSAERTHTMLEEKKANPGIQVRTITSEECADIMARAYKRIEAHRESTESFMNGASVFGWHDRYRYENKNLSFSLQKTFRHQTLDTLASKTWELIQCGETFAELFPSSLQASFFELQRLDDNNLVYYHTLQLGAKTDIRTKSVVLCSRTSVMDGDGCLLVFRSLNPRNFVLNEGGVKPGRDRRGRQKIEIQAEENWTNMFIWLLFQRSTEDGEHCVTEFGGTMFESPLLPASWWLVERLQCTMKVEQRVFGGPGLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQB3</accession>
    <name>A0A8K1FQB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Poli38472_004198</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQB3"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000068">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0140">cGMP</keyword>
    <keyword evidence="12" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="20">
        <location>
            <begin position="86"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="20">
        <location>
            <begin position="204"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="20">
        <location>
            <begin position="327"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="459"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="721"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="465"/>
            <end position="473"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 18">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="TMW66433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="773" mass="86285" checksum="5401EB414CCAEBB9" modified="2022-08-03" version="1">MGCINSVPAKTQKEFDAVVSATNAEDGAAVADHKVAVIMREKRAAGRRRDICAESVQFNAPLEIVPVPKSNESRDLIKQSLANNFLFYTIDANDIDVIVQLMTEKNAQVGDVIITEGDSGDFFYVVESGTFGIIVKGETISVAQQGATFGELALVYNCPRTATITCTQPGRLWALDRVTFRRLVARNQADQIGECKNALRNVSLLKPLTETQLGQLAEAAQIVSFSKGERIIKKGERGNVLYIIKTGTVVCSDAGDARGMEALRLTDGDYFGERALMTHEPRAANVTAETDVTLIALDRQAFDDLLGSLREVIDRNMSMRVLQSIHLLKNLSPYEKEKLFSALEPVSFKDGEYVIKEGDKGTTFYIIKSGSAMVMKSVENGEKKQIATLSSGNFFGEMSLLRDEPRQADVIANGALECLSLNQAKFVELLGPLQNVLNREAEERKQALAMADAIAMEDLEVMRTLGMGTFGRVKLVRHKATGKPFAMKILNKANVVAYKQQVNVINEKNIMARCNHPFILKLYQTYKDKNCLYLLIEFVQGGELFTYLHCSPNSPGRLKDDHARFYASHVLMAIEYLHERNIVYRDLKPENLLIDPQGYLKVVDFGFAKVVEDRTYTLCGTPEYLAPELVLGKGHSKGVDYWALGVLIYEMVVGYSPFAGANQADQMQICRNIVKETVQYPPWVSESCRDLISKLLERDQTKRMGITHGGARTIRAHPWFAAVNWDNMYKKKDTAPYKPRLADPFDTSKFDAVTESESIQPYHDDGSCWDKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS02</accession>
    <name>A0A8K1FS02_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS02"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="366"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="470"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="60786" checksum="66B1B4CD221B642E" modified="2022-08-03" version="1">MEGMVDMSSLEFTKCNEDVFNALLDHGAATATFAKGGSMLHRACERGHVLMINALIAHGCDVNGVAMGEPVFIICMTQFITSSIAQKWREYSSITVQMSTSKASKGGSSEKVEELLDIGVEPLVDLKDGKTALYVACLEYGSVALMRVLLEYGADANLVYRGERTIVHWASFYDLQDKVELLLAHGVDINAVDERGSTALLLAVHHVDIATVLLQYGADPYVLCGKEGSTILHLACERGLLDTVNALLAYGMDLNVVDAYGKMPLAVCLFWKEKRAKYWDALETAYALMSRGAEYEGSRENFWSVPKKDRPVATIVAMCVQHWSSEQLEDEPALTEALRRAYEQGGLEELERLLAQDANVHSYEPGGETYLHWATRHGQVEVVKLLVAYGADVNVPNRDGRTGIVNSLTPLRAATYSSNMEMVDVLLAHGADPHVTSREGDTLLHGSWDSGAIVRALLAHGADANTMTRRGRTVLHVAAYYARLEKLDELLTHGVDVNARDMDGSTPLHFALHNEAAVVKLLESGADVYALNDVLRAAILVQAIDWDEYEREVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSF1</accession>
    <name>A0A8K1FSF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19996at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487225" description="Serine protease" evidence="7">
        <location>
            <begin position="26"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="451"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1008"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1093"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1364"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="457"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1022"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1525" mass="166109" checksum="0A3C6BAC09129407" modified="2022-08-03" version="1">MVSVSSIVRTVAFFSALAASHAAAADDNSPQRTATIAREEARDWSVNATTREPVEQTLTAAGAAFMTVHFSEFNLAEGDVVTIRNSTGDVLDEYKGLGRGDLGKQGGFYSTVVYGDKVTVQFKPAADAKVESDSGFKIDKITRSTNQAKVSSICSADNTLPAKCYENAPNIPEAYKKAQAVARLIVNGAEACTGWLIGSEGHLLTNQHCIGTQSAASNLQVQFEAESPTCDDQCRASGSCKGVIAATTSTLVAVNADLDYALVKLDPLVDLSKYGYLKLRVAGAIENEEIYIPEHPGGKAKRMAVIVDSGEAARVHVDRSTECGEHRLEYDADTEGGASGSPIIAVSDNLVIGLHSCGNTQEVCMNSALDIRSLVHELRALNVVPADALDDPAAELPEGPWIPGATEAPAATTPAPVLDICPGFNFQNSCEEFTGGKCVWNDGSCSKNPAFTSVPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPALRLLPLRRQLLRHQSLRPKLQFKRPKLQPLRRILQLQLTRELLDQIDLKVSSGVPRTPRSDPELMFWRRNDKKAGATGRNDGVYNEDDDIQKLQRQFGIKTFSDKEVEADFLRLMGGAKGASSQGGLGLGLSPRSELALFGGGGHDDSDEEAKILRELNISGNLDSINVEDWSDDDDDEDDGAKVAKQELRSVLTDIHASAKEGHAARVNGTASSSLGKKVTHEEVHAMKLRAVELKRAGHIQEALAVFREVKVLEAQFQNAGAAASDPMTVTTRVETRTTSVRVKQAVEETHEAEEDDDVEVTDEDMQNPEYLAQLAMLGLSIDHPAPAKSQQPQETVDSLEQQIRETKERAVQFKRANQINEALAQMRLIKELEGKLAVVRQKTPPATQVPPPIQSSTTVHTKTVTSIHIPVVPGDVVEDPEVEVTDKDMNDPAFDEELKKLGLDPKAGSAAPDSTPLAVNQTAVAKMPRRYSSVNDDDLIDEFEDSDEENASFSADLAATTTSQEETTFTASVSTQEPPQAHNPTVPSDQEDIGFSRGLDVEELQAQLDRAKLAAVNFKREGNINAALDMMRRVKQIDNLITLKRQAQSQPGPVVTASPSPSPQELERQRKFAELEQLLVRFGDEATAKAREKLSINRAQAAEWLAKRKSYGAHMEKLQQMRRIPGQDPPPFHVESLSEQVKVEHLSIPEDEAHFRIVSVNGLQQVAGKDIMIKFNLSFPSSAPHEGKSGVVRISERPPFTTGEITSENAFRFRVQRTRGTQRLFEIKKAVFEVWRPGTLLRNPEFIARGYQELHPLLTVSQIQCHIPFVGSNRKPVGGDIEISLRIRTPLRDTEYQTVVTESLHVGEYPPLASSVAETPPLSVSTSQLPSPASSSSSVATAQSTPLPAPSPTHSTDDADLEDPHDLDMIISYDVINEEMEKIEAKLSSLSGPVAAELRDRFDSLALKKQLLEIGMQTGTLTLDMYTEQLQARIRDDRQIISRLLKANRRPDAARVLHRVKVMEKELEGTEEPAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C266</accession>
    <name>A0A8K1C266_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C266"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="65"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="35451" checksum="8C2C839659C99F60" modified="2022-08-03" version="1">MKSPSQVTRWTSVVNMYETHFEPILGQWTVDAVNAAQTKVQSMLSTYGSREETPQACDATPLTVVDVGCGLGAMTLAFAERFLASAEEKAVAPVRIVASDIWPDMLTHLEQRIESPRYERFAKQIETTVMDGQTLEPLADGSVDVLMSSFGMTIFPDQDKTWSSAHRVLKKGGVLVATAWAVESDNVRWFDALATAAHEVSTASAVADGSEPPALDLPSTKLATDSNKLPTRLEKLGFSEVIAYKTSHSSVVPSGDELMDAMLQNPGVAAYLKVLGEERFRGVMLDLIKDSYNSVFSGETVSSNEKRNLVRPVIIQNAGYVVVATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Z1</accession>
    <name>A0A8K1C2Z1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Z1"/>
    <dbReference type="OrthoDB" id="118174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="40925" checksum="4EB3DA91DB5E353E" modified="2022-08-03" version="1">MLGGKRKFTENPLTAKAETGSLKIKILRKEGAAGTTENALGVPRSPPRGRPAVAAPQAPSAPVSPPKPRPNRKHVPIFYQQASVSVTSSTDEVSRGQSQFSSDYDAGYSVSSTSSTTNQMERLQLDQPGVEYGTSAPALNPLFSQANTDSNGALSELLRHAFPTVAQIQPFQHHAQPYTTSSSSPSSALLMGTEPEALDPVQEHPASALHQLATSSTTYSSLSRESSTSSTNDHESSSYRFDPMRALQSAIKLATAKSSSSLPSFSYQNQQTMPSHIYGGSDQYSSIHSQPTTDDHDLGPPPMAAPAFGVQHSLMGGGIESQPVIANVNTRNFDWNRHQEELRAAQANGRPRSGSLPNVLAEDDEETNEHGHPNVHMWKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C355</accession>
    <name>A0A8K1C355_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C355"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001881">
        <property type="term" value="P:receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045188">
        <property type="entry name" value="Boi1/Boi2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902:SF27">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902">
        <property type="entry name" value="SESQUIPEDALIAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="54"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="203"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="32749" checksum="B82DBCDCC9491FAA" modified="2022-08-03" version="1">MNHRSAPNTRSNNGAGGGGSLPGNSSNAMINMDLELLVQSTQNLAISFGRKNSLEKFHGWLWKKSSRFSKWRNQHFVLDGGLLSYYDSFPTGQFVTGNPMSAMSGDTLFTCKGESSPAGAVRVAHVERSRKSKIAFKVFAVSGKIIDLRAKNEVVCNQWVERLNEAATLAKRQESLNSSTTSTASSTLSIGYSDSELDSLANIVDKSGWLEVGDKKSKRRRYCVLQGSMFTVYENEDPWAVPTSRAYVTQADKYNPSGCEFTLITQAGKTTKNLILKARSQDEMHMWLEALQNAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E3</accession>
    <name>A0A8K1C3E3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_010603</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="750"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="802"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="884"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="126"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="435"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="762"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1080"/>
            <end position="1314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1330" mass="147642" checksum="E44DE24E30A97D73" modified="2022-08-03" version="1">MTADAYVQSNDSTLYATPTTFFTVKTQRNDATTERVQEEASVTSVTTPLHPLERVGWLSKLTLAWMNPIIRRGLFTPLREDDVWPLPQVDRTEFLHEKFNRSYTQAKNKRARVSHALWSITKRKMLLGLACHLFYGAISMFQALLIKALLQYLQGEANLFSVTSGYTLAGLLSASALVGATVLDYGMFVTARAGVNARTIAISTVYQKLLRVRLPNLNGEILALMSVDGDRLADAFASGLWVVVSPLTVTACCLLIGFELGVHTALAALACIGCVLVFVTRQSKKIAMLRRELCIVTSERVKLTQEVLHGIRDIKMNSYEALLEKRVLMIRSQETALSSSCNLLRVSNTVLLSIAPMLTMAVSLIMYVYFGHKVTIPKAFTLLALVNTCHVPFGQFSNAVVGVIEGVSSIQRISTFITAPETEVHTLPECEEPAVELVDADFTWNTSISRPILQDINISIQPGSLTIVVGAVGSGKSSLINALLGEMYRVRGTTDMRGSIAYASQQAWIQHCTIRDNVLFGEPFDQQHYDAVISACQMRRDLDELERGDATEISERDAALNSSLKTRVGLARVIYRRESDVVLLDDPFSALDARVASKVFFECVMGLVKTKTRVLVLSSHFHLLPQADRIVVLSKGRIVGDGVYDEVAHLLTFLPAPVATEDFVRDFEVINACDSHEDSAWGELLSDSDVHSALIVSGSSLLSDCDHSPVLIRSDHFTSPSHYKKHRYTVQVTTLEEEEKVWSVSWRVHTLFLALSGWNSTLLCVLLVGMFLIAQSGLLAVDFILKLWTEGSLDWLNPHAPLWFYVEFVIIAGVLVSVSAVFLIDLSAESANRTQKRAFQKVIRAPLASFFGVTPVTRILSRFSRDLDQLDNFLPSVWLDLMRSATNVLSIAVVCGVVTPTVLVLYPPILSVSHYVQAYFHASSRELKRLDGVTRSPFLNLVVDTANGPESIRSFGMAEKFLAKSREMLDYNSKFFFMYQTSSKWFAMRLDWFVSSIVVVVAFTCVASRDSIEPASAGMALTYAVQLSMQFQRLVTLGNKMEAQMASLERIARYFALKKEGVQDEIATSPQPTWPFSGFIEFDDVYLRYQDDLDYALCGLSFTIQDGLKVGVCCRTGSGNSAVMNALFRTVELAQGSIRIDGVDIASISLHALRSKLTIIPQDPVLFSGTLRDNLDPFNDKTDDELFGVLRKVHLMDDASKWGAGLSHQVTEKGDNLSVGQRQLICIARALLRDSRIIVLDEATANVDQDQDRLIHVSMKENFEDRTVLTIAHRLESIADSDRILVMDHGVVAEYDSPSNLLQKPNGIFASLMESMRSAYVDEDLDSVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3M0</accession>
    <name>A0A8K1C3M0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3M0"/>
    <dbReference type="OrthoDB" id="118154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="6">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="604"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="648"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="127"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="684"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="766"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="790" mass="83579" checksum="CC07E70C6BD3D887" modified="2022-08-03" version="1">MNRQTLTEATTLQDAPVPVYLMDQIAAGTKASERDAEKTADFLLGRLAKTNLIVKLKALQIIAYCIREGSPVFADVIREEESEISSYLQYSGPPDPTMGDERYRRIRVASQEALVCLNDGSLPRNDAPAPAASAPWGAQQSQSSGYDQQQQSQYGGNNAYGNTGNAPSYGQQSHEQNSSSQGGYNPQTWGSNANSNAQSSYGGASRPAPYSDNPSSTPSYGGPGGGYGGPQNQYGGSGGYGGSSYGQNDNNGSSQQGYGGGYNAPGQQQPPQQQASGFSSWSNPASGGAGGAPKGGAGGMWSSSGYQKPTPTQPHAHTPQYTRDNRPTVLVGHAVSFSRPQSYGNSSLVGGIGGPSGIGSNSNAFGGSSGYGNSSSGFGSHQGRNSNAPSYIENMNRMLNSSTTQNALSGMTSSMQTVMDQAAASKLGETVKNLKKVGVEVKDRWDTRNMDKSIGASLADHDELSAGPQVLDRGYFQPQSMGQAPARADTMGEYERGLIDNLCASVGLARAPPADALKRFVELAQTLDHQTIGDILLDKLEDPVWQVRLKALHVVLALLNSPGSGPYMEVFEDNAGVFEELRNDAKPTVASKSLQVLRALGLADESTPAPRRTAAARPTARAASNPQTHSAPANQEVDFLGLGALSINDAAPQPPAQQPHVAAPPAPEISLLDGFDTAPAPVHQHQQQQYYQQQQQYYQQQPQQPLSPSQQYTQAAPPPQQPQQEYGDLLSLSPVQQPQPAPSHVPGGFLDDRSKALSDFGKDLFTTANSPRTSTSSQQPVNERSAFDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Q4</accession>
    <name>A0A8K1C3Q4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Q4"/>
    <dbReference type="OrthoDB" id="91810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="319" mass="35606" checksum="B7B161C9B547DD9F" modified="2022-08-03" version="1">MANLPIFFIHGAGRSAADGIVFDRFATEQRPVISLNFAENEDTFHPLPDQVQLAIEQIRSYTRDDARFNNGYTLIGVSLGGVIARGIVEEMDDHNVQVLISLASPHAGLCHGPQADPSMAQQFGIALLNSYSLPVELFDFASYSIDSIKDGHLLVDLMEVMQKHPELTQNSSITSLLRYPVRKIWLDLKPYLATIGNLEQPGGEGQQRRKSNLLKLKEFHAFTSPQDGVLEPYQSGVFGHYSEVANSAELLDNFKSLGMVDMKDTVEYMQDTYGLRSLDERGALFRHVVDKVPHMCWIADYDGCYVDQVLDTNLGPILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4S0</accession>
    <name>A0A8K1C4S0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4S0"/>
    <dbReference type="OrthoDB" id="148089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="45088" checksum="CB41CF4A500B2D02" modified="2022-08-03" version="1">MEPNENVELPELEPVVAPLTAEEKQARQRLHVRRTYYRKLHRLQTLRTEVQQLEAQYQQLVDRNKLMEACAFVADLPEFLDEKEYQKHLRLREYQEVSGLQTRLQQQNEALQAAVADYDQYVEYVKTLVDTEQGWSKYSSSSSDETESPETRLSSVLNQSPVVIPTLRAPLTVEYCRQVALQRYEEIRRIRESPDALSTGASVFGWRDKRHHDKDLVNFYLTKTFPDISVEQLMVRGWNYLSAPRHMASLYSASITPQIFMVQRVDADTVVLMRVFSSADGNSLIRSFYLASRLRIPTGYCVIYRSLDNSLLAPYQNPPGIQDRWVNYNTWVTMEHVGERGQSCALSFGGEVHHALAAMSHAWMIEVLYIVMRWESLVVGSRVVIENGGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y6</accession>
    <name>A0A8K1C4Y6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_006644</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y6"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445903" description="glucan endo-1,3-beta-D-glucosidase" evidence="15">
        <location>
            <begin position="25"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="335"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="351"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="45568" checksum="96EDE297BCA7DB47" modified="2022-08-03" version="1">MALHAESWLRRIVLGLLLFLPTTPLSKPPLNPHIMVNAHVWTALTALLAASTTTTSALDKELYGVNYDLRQGPDWDPAKCKNAKTIASELKVLSTITKNVRTYSLADCDVTPVIKSAKELGLTVWLGVWISGESKVFEAEVETMKELIKAGLIDDNIVGFNVGSEAVYRKDVTAEQAIADLTEFKKLLKDNDLAQPVSITDIVDVMLQYPEMIEAGDVVTVNQFPFWEKMDVKAAAAQFRKRIQPLLSLAGKKEVIISETGWASAGKNENASDATPESSARYLNDFYLVAEEEKWKYYYFQAFDSPWKAQIPGEEDTVEGGFGIFDKDGVMKPEFGDLKISPREDTITDVGSASSDGAAGTAGTNGQTASSGNGAVHASSGSGASGTNSNSNKSSNKSPSPSSAVSVATAMSAVLVALSAALVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5C1</accession>
    <name>A0A8K1C5C1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5C1"/>
    <dbReference type="OrthoDB" id="101060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461964" description="Expansin-like EG45 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="27954" checksum="F89DF5FC54B69279" modified="2022-08-03" version="1">MNMGVCGTALTLAVSALALSAHAKEVFTGRATTYGLIDAIGGSCSVRKSPLGVDPSLFVAMNGDQYDSSSSCSRCLSITGPKGTILTYVADICFECGHGNLDFNTALWNTLIGGDPRIEGISWFFTPCPDEQEKFCMKEGSNPQWLALQVANSRDGIKSMEISGVKANVIGITSFYQATSSQGFDLNNLDVKITSNSGIPSKVKLTPKSYDGCAMPSGNDNAQSNDNNNNNPPTTIAVDLTGVTQDLSAWRSYRRRHHKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5F4</accession>
    <name>A0A8K1C5F4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006643</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="165098at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000216">
        <property type="entry name" value="Type VII secretion ATPase EccA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
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            <end position="1382"/>
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            <dbReference type="ARBA" id="ARBA00010378"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00022741"/>
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            <dbReference type="SAM" id="Coils"/>
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    <sequence length="1479" mass="166567" checksum="7A244A64E2134312" modified="2022-08-03" version="1">MVDARCATSSTLLHCDSTIEWKCGSGRHNFDIAVCKHGPPTMCPSCSFDLLEEELAATQSICDLTAEDIPWPPLGGPLKISWPTFASPIELSEADKIEFYTRKLILLEGFKRWVTKSKDEWSRAVFRPQIIPVFTIRKSVTRNPTELGRVEVKDFASNKSWNSIDVHEWTNANTNFMLPPARSTHQVIFGYLFSLGVNSSPSDAPTGKFGAGHLRWIESQQNAFGYDCAFLAKKKNGLLGEEGTIRVWDPFVIAPCAEARVSAGQRDMVLKQAAPERTYWSTASRFVEYDRAAMLDTEQAGDNGVAGAAFSVPSVPTEYLEKLHQVLAALTYPWAVGIHTVFPWLGKQLFLGGETLPESVERQLREKLGFMRQGTAPPAKKIGPFAGRRFMQQVVKQQPFAEAELFHALELLWIQKENVTEATTLLESYATKMTGRGKACHPLLLLALARLTARLKAAVKPSELFELFRQLYPEATELWMTREELEGMGVPADDDLSKKSISDPVSMTPAEQWEKLKTESACKSKAMEELLKMVGLTKVKRFAIQLFKSAVAFQRMTPEKRKKNAITQNFCFLGNPGTGKTTVAKLFAQILHDSGMRRNGTAELCTAQAVKDAGSDAFRDQIKKAMGGVIFIDEVYELDPMNDPKGKPIVAELLVAAEDKRDDLSVIIAGYEDDIQQKLYAFNDGIRSRFIEVTFDDFDEADLRIIWDGLLRDREWTSDENAGVVACRRLARCAGRKGFGNARAVRQVFERVTQEAMSREDFDGIMELRTIDVIGERPTKNPKLQLVMRELDGKIGWKRIKQRIRELIDICDKNYERELKGIDVIPVLMNRLFLGNPGTGKTTCAGIYGRILKQLGFLSNGDVVKKTAGDFVGQHIGQSQTKTNDILKQAQGKVLLIDEAYNLDDQWYGKQVLDVLVEKVQGTDSDDIAVLMLGYEHQMKEMLRTQNPGLKRRFPIEYAFYFDDYDDQEMLDIFMAACKRKSVRCSMDVAEAVIAQLSMQRHQANFGNAGAVELILKSAMANASMRPLVNDMIVLELADVENETLKRAKEDEGKAQGVEADDPLRLLDGLYRMENIKHELQRLSTRIQVAQQEGEEVPEIGHFVFRGSPGTGKTTVARAMGKILHRMGLLGSDKVVETSGLDMTGEYVGQTKKRVEEQLGQARGAILFIDEAYELGKGHYGEEAMTSLVAAMTDPRYVGMVVIIAGYPADLDEMLNRNAGLKSRFTRFLDFRDWETHDCLEFITGRSNRAEYRLMQDTVDCLRRMFEKLRSFPGFGNGRDVDKVWKSLLECRAQRVLGKPELERLITLDDANGAWQQVLGGRAPPIAKKLTQPVAFSPDVKFLDAGNQPPLPRVEHSHKSTEQPNAREDEEPETKDEPDEYELERVTRDAGVDDAVWEELERAKEAYAQLLRDMKDAEDRRKRDEARRKLEKERAMQTKLRKLCLCPAGFQWHRCGGGWRCGGGSHFVSNEELERKFMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5R9</accession>
    <name>A0A8K1C5R9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003021</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TPR_Sec16"/>
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    </dbReference>
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    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
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            <begin position="1393"/>
            <end position="1515"/>
        </location>
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        </source>
    </evidence>
    <sequence length="2391" mass="248809" checksum="64E9E6C996ECFB58" modified="2022-08-03" version="1">MDSAPSSQRSVGGTPLAPGRRYDAPLSSSGSTSSPFAFPSPFQRTPSANAAPTGPSTSSLLNTTTPAAARPRPSSAGNTRLRQKPSTPTGTDLFSALAADRNAGPPTAPAARTSTGTSLFKSTTSAASSLFASSSTQRSTGSFGSSNTQLAASAANATQLFSMEDTDADDGWGGLDSPSSILSPVGTTAKATKATTDDDFSWVEDDLEPTPPKQTAPALAKPPSTPSSMFPPTTATPSTPSSMFPPTNATPSTPSTSLFASTRSQSSTPARPTTSLFSSYTPGASTFGGSRPTTPAPAPTPAAPVTTADFAYSAKAEPTVADDDQGWGDEWGADDDDVLGAIDKPQPAKPQPVRTSHPPTTSASFAFSKPASPFVSTPTTAIPPATKAPELAAVISPTTAKEGEFWGDESEDGLFSDEDAAPETPAVPAPAPVVSPPVQEPPKASVFEATTSVDANEFSYKTEATPTQQSAPADDVASDWNDDAWPDDDQLASSTFGESSLSAANNAFATSAPHASAADSAFMSTQASAANASFASYGDYSAQTAESAPFANAAEANGSYFASTTSYEAATTSTQESYEFQSHASYETPGHNEYSAQCSSGEYGYTDNSANTESYASSTNREKQANEAKNEWEDQSQTQATTEPTPFASSSKPSSVVSFGSSSFTAAELTYGHHQGPSSDAEVGSTVSFAEVSSAGATFGGSDNASDAAYLDDNASETRSNFGSSSAGTAFVTEAASSSDGQGSYDDSTITYEPSEQYGTNSSLPDEHQDSRDAYEEYTHGASAAEGAFGSSSQAQDSTGLFGASTSSASDAFASSSYATTTSVTTATTSSAFETTQESTPFGSTSSAPNDAFAAPPTQEPEASNESPFGATVEDSANPFASSSANDGFAAAPGFETAGEDAPNPFGAPEGTVDDHELPTSEAGDLFVNSPVAAAFGGFNQPSDANGYFGHQSDTASYEPTGYGYEQQYGYDNNGYDQQQAQYGSYEQHEQYAGQDYYANDQSASGGFGQEAAGGDANAVFGAGDSAARWDEVVAESDHMQSYEQNEAFQYDQSKEATIEPASENVDNAQAPVAEEPATWYQESNNATPFAEEPNGGAWPPQDDSSHFGASNEFGYSSEYHQEDTLAEAGAVPSETIAPPQTTHAAEELSQGTPFGGDTQEEVDSSAMFGGSSSAFDGFGAPQTQANDPFAASQQTHDAYGYASAAGYDASQGYDASQGYDASQSYDASQYAQHRYAQDPANAQYPEYEEKAGVPPAQTGYQSDAYFGNSAPAAGPFTHGQHAPSTAAPVATGPPAPPAVPSSYPHNAYQASPSYGATPAPTAVPPVADAAATPAHGLSYEETAYSTHGASTGDDGYPMPYTPKSAAIHAAKHTPVMTSNKYKDPTAVAPSCLVSFGFGGNVATMFPKRKLRLNAASYTTRNSPRNPMANQFENTPHGELRKGPVQVYRMEQLHPKNTEFEQLDKFPGPLTENLTEETILQYVEEKIKSIRSSSPFEEDERLLLGILRVLIKCNGRLRSDPKDNPSNPNSPEVQLVSLLKESDQRRRRHKPSAFPPPKPVQYPSHPDATVRNANRIRELLLLGDRIQAVDVAIQSQMWPEAMLIASFTGKDEYKRVLCAYFSSHYSAGDPCRALYMSFADQEEKSVHEPQKLMHAADEQPSSAILSSWVIHVQMLLANRTADTNKILVELGDRLWKEANAVVAAHICYLLAGVGVEAPSPNSKIALLGGDHRTPEEARFYVSPTTVQRTEIYEWIQKRAHPNAMTMIPFQGYKLIYAMLLADHGKLETAFKYVNAMLSVIRSVTANMKPGTSMYLEGMQGQLTVLDDRLRQHLGQDRAESVAAAAANTKTGKWGLGNALNLMGKIVNRVVEGSDAPPQASGAQQTSTSLFQGAPRADGTNATPEYPSAAAYPSQLAPGDLNSSIVPQGPPSNSGIRLYASQKAPNSGRGSTYGAQPTPVGGQEGYGAPAPPVAAHGNTYDAPAPPVAPHPNTYDAPPAPPIAGHTSGYDALAPPAAGYAGGYETPAPPGSGSGDSYATPQPPGSGSGASYGAPPATTDNAYGTQGPPSTGSQGPTFRAYQAPAPGSGRGNKQAAHPAFSHSFKAPGATQAPANTSRFSAPPQGAADFAEPPAHGGDNTLTSAVVPPTSQPPAAQPPAQFQKPAVDLSGEGVSQELSAHASPKSPKRSPTRPLGEGPGSDKGNKSPKIRDAKKAGRSKTPPPSKSSSSGWFSGISRMIAAKMNPDAKVAKLGEQMEAYFDEEKKRWVFPGETQSEEPTMPSAPPIGPLPGSTPSGGPPGTQSAPGSISGGSAADDPLSALMAPPPVRSHATLMKSDPMAAMMAPPTRSMYGQPRGAAPAQKRPPKRPQFAVFKPVAAPAQEAAPADEPPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C611</accession>
    <name>A0A8K1C611_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C611"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54437" checksum="043AE81DE689CEB7" modified="2022-08-03" version="1">MGEKSEQAPLLKPQQERQARGRRGLLVGLAAVVSALVSVAIYANGTHSTAEPVVYCDTTKQEAGYIKLPNKVDDHYWYWYFESRSNPATDPFVIWLTGGPGGSSLLGMFSENGPCTVQEDMTTKVNPYSWTHSANVLWLDQPTGVGFSYGAADDLDSTETDVAENLYLFLQEFLRKHPELRENAFFLTGESFAGHYLPASALYIVGQNAKHSNSSSDDVIHINLEGVAMGNPWTSPIVQTSTTTKVVKQIRESYNITLVPESQLDEIKSRTDTCAEYHFECQKVPRNIMACVNATSCDVDLTEILTGSVRNQYDIREKCTEVTFGMCTNATASRHFEEYLNLDHVRRHLNVNLERVPVWLEGSEDTNGFITGGDYSKAYDSTVADILEAGIRVIVYVGDADLVCHWPGNEAWTRALEWHGKEQFNAVEEEDFVTHDPLDAAAAPVRAGLLRSFENFALLRVFNAGHMVPQAQRAVALDLINRFFRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6R3</accession>
    <name>A0A8K1C6R3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6R3"/>
    <dbReference type="OrthoDB" id="157215at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035481551" description="Chitin-binding type-4 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="25555" checksum="FBF135E99EF20A0A" modified="2022-08-03" version="1">MVRTAAIIASLALALPAAVNAHGSISNPKPTFLDIYNKNAPSVLNAGTPGYTGLDYDLKAEAEKLGSKCGKTDANGASQPIPADGVISFDISAVHIGPCVVYLGNEKVAESKNCWTDYPDKKIKIDTSKCGSGCQLRWIWMATHTSPWEFFDNCVNLGSGGGASTSTDTTPAPAASSAAPAATTAAPAASSAAPAATTTTPSTTAPASTTAPSTGSGKYKYCGAARADSAALGEWCNTNCPSFCPGDMCCEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7C7</accession>
    <name>A0A8K1C7C7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7C7"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="98"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41618" checksum="E7054425EF693703" modified="2022-08-03" version="1">MVFCCRSRRPSYQARETVIKGGGGDTLSPSEDVHRPDFQAPYAPPPTSQNQSQNSIQQHRERPASQRSEQPPVSSVTSVAGDHCFPSLVSYRLDEQEVLLTRKLATSAFSIVWLAHYHGMDVAIKKLVNGTDDTESFAREVEIMSKLMHPKIVRFIGCTWTNSFDLNVVTEFMAGGDLRTLLDNRKVALSWYKEKLSIAIDIAEALAFLHNQSPKIIHRDLKARNVLLTKKYVAKLNDFSRSRDRSYTQTMTAGVGSVSWSAPEVTLGQYYGEQADIYSFGVVLSELDTRDSPFEETSGKRSGDRRDIKLVIQVAKGEFRPKFSEECPDAIQRIAHACLQYEPTVRPSAARLVRLLKSFRQEQEKARTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7E6</accession>
    <name>A0A8K1C7E6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRAPPC10/Trs130 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000127">
        <property type="protein sequence ID" value="TMW57680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7E6"/>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477129" description="TRAPPC10/Trs130 N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="30004" checksum="A093F597D8EFC0D1" modified="2022-08-03" version="1">MWRQDMRLVVFFGIVCVISGSSSNSGISADRICKIETLEGASVVGAQSHHETQWTELLLRLRRWIMEAFEFKCFQYEEEVRVLDTKRSFRGWDFAPFFVAKERLALIYQQMYLLDDAIRHLDELEAIFLSLIQSENRFEENSQTFVYDAQHPIFTTSPLALDMAEMHHQIARHQAPALLMRLYFFSRQIRTLYLMGDFKQLTERAMGFIPSFHDLLLSSLGGIAKNVTMALHQWAVGACLEIAYACELSWSGHDYQILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7M8</accession>
    <name>A0A8K1C7M8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013423</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7M8"/>
    <dbReference type="OrthoDB" id="10018333at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009738">
        <property type="entry name" value="BAT2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07001">
        <property type="entry name" value="BAT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="BAT2 N-terminal" evidence="4">
        <location>
            <begin position="68"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="5">
        <location>
            <begin position="257"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="33817" checksum="A431DC3B42CF24A7" modified="2022-08-03" version="1">MWKDVATRRVTASERDLPTNTTKTWWHAERRVSAASSAAIAGEIDAETRAGDTQEATPRDERMTASIARSSSSSKTKFSSRNLNAVYKAPVSKSSESAGFPSANRMLVLRPVRGAVGVAKANTVAAPTPINTPSLRKENMGQDIHVNLVPSGRNGWGNEKNDEKSTEERRPSEPHEASEHQSSGENVWNGGVHSAPTTTLSQPSGNSAAIIVIIASVLDRDPDGVLIRVDSVRAVCGACRCDRVAHQSSKETKMALSIRAKNFIMGSSLGAFAFGVFAYTVQQMSKDDFAELDEVAKVNVHQSGAIKATPIKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C818</accession>
    <name>A0A8K1C818_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011694</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C818"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000904">
        <property type="entry name" value="ABC transporter A family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="43078" checksum="C3F36A342B1D6869" modified="2022-08-03" version="1">MAVRGLSFGLKQGECFGFLGINGACKTTTMKMLTGDVVPSSGTATLSGSDILTQQIEVRRQIGYCPQDNALFDLLTVREHLELFARIKGISSEDLDEVVADKIQQLNLSAFENKLAGSLSGGNKRKLSVAIAMIGNPKIIFLDEPSTGMDPVSRRFMWDVIAGISTRSKSATIVLTTHSMEECEALCSRVSIMVGGHLRCLGSVQHLKSRFGDGLVFDVKMASPSADEMREMIDRHFSNGQLVVTPMELEEKCAALGDASFAGRIVASHPSGYNLATAMDRDGFVRAEAFCTWFVEETRFEELELYLRRTFGEGNIQVIERQNNFCRFKLCGSRAQLRLSTFFERVERVKAKMHIREYSVSQTTLEQIFNQFASQQAEEQGVARGMMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C882</accession>
    <name>A0A8K1C882_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA-binding S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C882"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF3">
        <property type="entry name" value="RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="5">
        <location>
            <begin position="77"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="314" mass="35448" checksum="83431AD117F284EE" modified="2022-08-03" version="1">MSMRTLRLGALLRRTEASVDGLVRRLPVYEQRRSVITIKKFYRIPREPTAKAKAVDAAKVSQSKAQDATASQPQKPVRLAKRIAMAGISSRREAEKFIQSHEVTVNGRIVTDVAATVDVEKDSVAISGRPIQNATRRKVWMAHKLPGELVTTNDPQGRPTIFDRLRVMGLTQHMMPVGRLDFNTEGLLLFTNDGEYARELEHPKTEVMRVYRVLVRGSVTPSKLDELRRGPIVDGIKYRSIHATVQSTDKKDSWLQVRLAEGKNREVRKALAHVRVIVKRLIRVQYGPYRLADLPSGSVLEVRPKSLLPKTKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAG4</accession>
    <name>A0A8K1CAG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAG4"/>
    <dbReference type="OrthoDB" id="343609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480526" description="Kazal-like domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="32"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="90"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="152"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="206"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="269"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="322"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="39853" checksum="7001C395B06A19B9" modified="2022-08-03" version="1">MKIYVAAIAILGFAASQVTAHDNATSPSEYTVVSTIDCDEHAMCTSDYEPVCGTDGETYSNMCVFNNAVCDAMDDGVQLDKLFDGACDDTDANLYCHIRCTKEIMPVCGSDGVTYSNGCTLLAGRCETPSLTQVHTGECENENTEETRGYGEDMTSKCSNGCPRNIAPVCGSDGVTYYNDCLLKVAACENPDLGLTVAYDGECDTEECPKFCPDAIMPVCGTDGLTYDNECLLNIAACEQQDPDLTVDYEGECDDERPRPANKQPVTEETTHRACPEIACTDKYDPVCGTDGKTYSNDCYLKDAQCEHPALKLAYKGECKKTCQKPICLAIYEPVCGSDGKTYSNKCLFSYAQCLDAKLSIQFNGECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAL1</accession>
    <name>A0A8K1CAL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAL1"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="51432" checksum="DCDD55D35B9DB2E6" modified="2022-08-03" version="1">MDTRVGWEHARDSHGRVLYVNPLTREISWSLPTDDPQTGWQETTDGDGRVVDHTARRHPGRPDPKPSSYEGLGRVADPLSPPLVHNSTVAVDRGWIYWLARFSDQPCKDMELLAERSDFIGAFWLHDRLKRIGCLECSKQFMYMTVESADLAQVTWHMRNCEIHSLQDWLYAAVWIGRVDVVDWICRDKSSVNHLRVQSARRGPRKRKSLFHSVDASLVSIQECFESELMEMEAEMNVNEEAAQKGAAFSALSSIAVDLAATHGNRHILDCEPLHAASTTSTGWETLDPMSQDDYEVRVGCTVIGLYDAIINGHFEIVQWICDNQPVLSNWPKLEDGAQLLLKLLDKPTRKDMLEFFGRERGMRLDPHDLEEAVRRQDVERVRLIGELDLVESASSAVDIAAVQGNYQLLQILVREGAPLECTAQAMDGGPREATCELSNSYMHLAHPAHVGRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAW4</accession>
    <name>A0A8K1CAW4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007212</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAW4"/>
    <dbReference type="OrthoDB" id="162479at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035446037" evidence="3">
        <location>
            <begin position="23"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="27445" checksum="9B4D2AC2376FE8EA" modified="2022-08-03" version="1">MWQRLAVLGLLAVNALTTGTFASPAAYNVTGDEAGRRLQRGELPGPDKTQMAAVNFDVFVLSAYYWPGHCANSKGIAACTTMPAQWKSGLVVHGLWPSYSDAYKKTNKLAANAQGPDGGAMKCLGKAYDKTKIPATAADQLVFPGTGVSNKSPDFYQYQWNKHGICAQMEQKAYFTTAVTLGKAASAKLPAVPTAGTIKAADLQKSLGSLAQPTCFRDAKGRTILWFVNFCYKRTTDIGGQTACPGVSNCSGTITLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB49</accession>
    <name>A0A8K1CB49_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000146">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF16">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="1083"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="530"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="586"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="705"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="866"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="81"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="288"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="628"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="714"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="1163"/>
            <end position="1170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1445" mass="162684" checksum="1EA939C7C0E73BC8" modified="2022-08-03" version="1">MSRVADAVTAPSVENDVAMAHAGAQVAPLPHHIKEFHVGALLSDPSDAVVAPRREEEERYIPVTLAKAHLARVVQDMHAMKENQTRQVNVIVEQYKKMEQESKTYYEEYITTLKKRARDKLTEAQDKYKALEDTLHEQTKRAEEERTDMVEKHAREEEAHEKAAKRMRQVLETSCVQYEEQMTWMQKQVALELRRVVGEREQEMHGVEVCARNQLLMNWEDVQAASMRQTDRLHRLQHDMETKEAAYRREIRRIQEQHTIDHEVYRCVSTVINRVVDMEHQLVKMKRTKELQTEIKKLQQEVKRTTQQHDGLMKRLHEAQARWERAERASVKQAMDSILRTIELQPKEPRYKPPVKATMQDNGFQTQTEEQKEVKAVRPSMSDVGIETNPPPARQDAETEPMSVVPELSLLSGEQLQYEADVERYKERNAALVRSKQELRVVKTQMQSCLEDKNAAKARIKQWLSDFQAKYGRDPTIEEKAQVKELYLAFKESEDKYNKTKEQVAVLKTAHHERVVEVEALSQWHALAASSSRRAKDSDEDNSAREQGSSDQGPRPVSREVLPTDSSAKVLQLEDEVKSLRQALETTRLEQDKPVSPQNQESSSHALDTVPLIAEEKATAMTPRDEVSADEKQQLKMVREELTKYTKESKALNVQREELRTTIAALTSEIADRREEKTRLETQIEQLRLHAELMESDDSALLATSEEKHGAERQEEEEGDEEDQEEANTAVEEDQDMAADAKTTPQAPALTDNERADGAKEAQLLTLLREAIDTGKMQWNRGDKAKCHQIYVRACEKSIELLREMRTPRRVEVGILRSALQEASKLPPARSSTILRKQLDMLVAMCENHAKDREAKVAAAARAASITPVTSPVSRASPQRKAFKKGTAGEETTETPNTSSGPVNKALEGELKQKLKALEAKQKADKVRITQLEAALSKTEMQLSAASTGGGNAGGANSVLLERKLADAEKKHTKAMEDAEKSAKKEVTALTQQLQTVQAKSQGLQEQIDKLTKELATVGGKASQLSKIEEEVVTLRTKAAQVESLTVELAASRSEYGKLETSYKEEQSLRKKYYNMIEDMKGKIRVYARCRPMSSSENERGCQTCVRFVDEFSMELKTSHGPKTFAYDHVFPPASTQDEVFEDTKNLLQSAIDGYNVCIFAYGQTGSGKTFTMTGSESLPGLTPRAIHHLFRLAEETRSNNTITFQAFMLELYNDNLIDLLHLVDGGSSDKDAPKLDIKKNDKGMVFVQNITTKGCTNAQQTLKLFDAANKKRQVGATKMNAESSRSHSVFSILIENYNKTTKATSIGKLSLVDLAGSERAGKTGATADRLKEAQAINKSLSALGDVIAALSSNEKFIPYRNNKLTQLMQDSLGGNAKTLMFVNISPADYNQEETQTSLQYASRVKLITNNANKTSESEQVNRLKAIIRQLRSGKTDVDLEGVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBH7</accession>
    <name>A0A8K1CBH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Solute carrier family 35 member F2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBH7"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="37337" checksum="D60BD287CCBB06EB" modified="2022-08-03" version="1">MRGAITTFYAQHRVLVLGQLISLLITCTGIFTQFLNQSYEIQIPVTQSAGNYLLLCVYLVYPVMMYRTQPDYSLEIAWWKYALLALADVEGNFLVVCAYQFTSISSAMLLDCFTIPVVMLLSSMFLNAQYSREHFVAVAFCLGGISVLVISDIIRDAEDWSSSSWSLSALYGDFLCLLGSAIYACSNVAQEYLVKKKNRRLEFLGMVGLCGFVISSIQAYLFEGAVIAHADWSSGSVLCLLGYVVTLFVMYSFTSVFMKTGDAAVFNLSLLTSDFFAVVAARFLFNEHLSSLYFVGFTMIVIGIVIYNRSPPPTTSLDDKMEAAEGTTATLLPSHHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBY3</accession>
    <name>A0A8K1CBY3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBY3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="90" mass="9986" checksum="49544DEE5F9AAD46" modified="2022-08-03" version="1">MEQASAEAKTMRLEAVCRLYSGFLCTAASHSIAELDFSLAARQLEIRKQSENDVEVGGFHPGPSSLLANSWLTKSMLSLIQDGFRQFTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCP0</accession>
    <name>A0A8K1CCP0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="168475at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36493:SF3">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36493">
        <property type="entry name" value="NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035422060" evidence="3">
        <location>
            <begin position="33"/>
            <end position="1928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1864"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="958"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1386"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1417"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="876"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="959"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1465"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1928" mass="196068" checksum="F9E200BEC82DD748" modified="2022-08-03" version="1">MVYPRSEGTRSLAKFVAVCAVNLCLLHGTVTGAALEGSACGISVAESDAAVGIRIVSDPSCVNGGLGCIDNVCRFCKVADTPQAAHLFNCSDYGYTLPPTIAPTSTPLPTSATPEPSTGSSSALEPCGVAPGDQAVGVEVFVDLGCKYGGVGCYNDHCRHCKAYDTPQSGHLLSCKEFGADFPSPSPAATTVAPAPADETPCSVSEGDYNVGVSAVLDTSCKYGGLGCYSDHCRFCKHKTTEQSAHLDDCSSFTHPPTGSPVPATSTEAPVPGSVSPQPASETPAPEPTLEGPEPTSDAPAPTSTSPEPSSDAPAPSSESPVPTSESPEPMSESPVPEPSSESPEPSSESPEPTSESPEPTSESPVPEPSSESPEPSSESPEPTSDAPATSSESPVPKPSSESPVPEPTSESPEPTSENPEPSSDSPAPSSESPAPEPSSDSPVTEPSSESPAPEPSSESPVPTTEAPADAQCGVSEGDYNVGVSAVYDAACKYGGLGCYSDHCRFCKYKTTEQSAHLDYCPGYTAPPAESPAPEPVSSESPVPEPSSDSPVPEPSSDSPVPEPTSESPVPEPTSESPAPEPISDSPVPEPSSESPVPEPTSESPVPEPSSESPAPEPTSESPAPEPSSDSPVPEPTSESPVPEPTSESPAPEPSSESPVPEPSSESPAPEPSSESPAPEPSSDSPVPEPTSESPVPEPTSESPVPEPSSDSPVPEPTSESPVPEPTSESPAPEPSSDSPVPEPTSESPVPEPTSESPAPEPSSDSPVPEPSSESPAPEPSSESPAPEPSSESPAPTPEDPFGGTTDVDIVETGCPYAASSGDVSVGIQLVGDESCLNGGTGCFADVCRFCQFRTTPESAHLYSCKSLGYDLGSDTPAPSTTSPAPTPSSAAPSTGCPYVVPDGDFTVGIQLVGDATCVNGGVGCFAEICRFCKFRPTPESGHLTDCSALGYDFGSNVSPAPSTSTPEPSHEAENPVPSIPGNCPLSVSAGDFGVGIQLVTDPSCVNGGLGCLAEVCRFCKFRETPQSAHLMDCAAFGYHSSATSPPAIETPAPSSENPSPADGTPAPVDETPAPVVIVIETPAPSSETPAPVDETPVPSDETPAPIVIVIETPAPADETPVPSDETPAPVDETPASVDETPAPVDETPAPVDETPAPSSETPAPVDETPAPVDETPAPVDETPAPVDETPAPIVIVIETPAPVDETPAPVDETPAPVDETPAPIVIVIETPAPVDETPAPVDETPAPVDETPAPSSETPAPVDETPAPVDETPAPVDETPAPVDETPAPSSETPAPVDETPAPVDETPAPVDETPAPVDETPAPIVIVIETPAPVDETPAPVDETPAPVGETPAPVDETPAPVDETPAPVDETPAPIVIVIETPAPVDETPAPSSETPAPVDETPAPIVIVIETPAPVDETPAPVDETPAPVDETPAPVDKTPAPVDETPAPVDETPAPVDETPAPSSESPAPVDETPAPPSETPAPDDELPIGQPNDIGDTVSGPCPLTAAEGDIAVGVQLITDTSCVFGGTGCLHDVCRYCQFFKTDQSKHLELCSSFGYDFEVSTSGTPATSSVPTTSTVAPAIPLICDQVASEGDKKVGISMVTDPSCWSGGLGCKDKTACRECKLWDTEQSKHLESCDKFATLDDGADIDFVPIGATVAPVSAPVPDSSVPASPVPSASLICDQPASDGSKKVGIDVVSDASCLTGGLGCIENTACRFCKLWDSPEATHLDNCSKYGPPVTAPPTAAPVVAPAPLTSAPALSPAPVTEPPLDASKCSEYVSEGDLPFGVWAMADSSCATGGLGCFGQVCRFCKKYDTDKSSHFLNCADIKPSVSMLKMASVTSSADEVATKSEDKTNILLISLGGVGMVAAVALFGVGIKRTINRASNLDVMPAEVADMDDEDAEEVEDVVDLDENSLNAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCV0</accession>
    <name>A0A8K1CCV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014505</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5582218at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00694">
        <property type="entry name" value="DysFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035447324" description="PX domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="11">
        <location>
            <begin position="131"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="RUN" evidence="10">
        <location>
            <begin position="701"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="1188"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="9">
        <location>
            <begin position="1323"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="994"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1315"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1460"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="998"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1315"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1484"/>
            <end position="1497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1694" mass="186724" checksum="82BEA090C10643A1" modified="2022-08-03" version="1">MWRRLAVGLVALVALHRAELLPAAVHAALWTATRLGHVVVLFSGGIVFWWLLRSYQLATEQELFDDALSKYKFYQKYRPRETRSASGTRGNSYGNDEGGGGGYGMLDAGFQLKVVKRLPIVTHLRTSWNLPTEICEEIATFVNLAVRDYVSYWFQPISANEEFPHDVRFLLADMLGALAARLLEIDSSLALTIAAKSIEILRLHLGWFREAYAQMSEEHPQIFQGEESDENLQQRQALIASYAQKSQFLHPGCVAPPTTAASTTPTSSSSSSAKKAPTDPAEVLYLRHVATQLLVQLKPEFGVQAETNLFVSMVLNLLRESLVFRSLKPLVEYSQPRYANELVVSILSAEVDEDSDPLENPTAPSSSPVERTSSLSFSMPQLNPTGIELRKPLNLTKTFLYRASKRSTEQAEAAFQAVVGAVSTAASHAGIHGNGHSLSTTSPSGGDVTFDTEFWNDSLGFSAVSPLSPTSNAGVFLSPRGQGARSSGSGVVPTTPPPPSSQNEKKGNFVSMFSLEDRINFPKAPRFVSPRMPLGSHGRTSSQDNGVPTTHMEDLKNMRANLESSLNSSLFKVKKKFRDIGGQLHDPLSASIAMPTSTQAANLMKRPGKLFQKALRRAETAPDGATGANVALPVSPVATADLFSSITPPPTPPSTPTDGALPLETTKSVDLQVADRVLTLLDKTVASYLKMYQERPEMRSSARSKELYALVSALEDVCMLGYHRPDPLEMVGDDGVASEDGPIDPDSDPAPPLSPASLALMDPGQLYWNYLACDRPASPFLNEHWRYVATQCPQCADTESFYSTRGVQWLLIALERGVLWEYFTGLHLSPQVTQRFYDEQSVLRQPALIERVLKTLLPLNQLRVSLEIPHVLGRKSDLEDEWGVTVRVTPASRTVRVVESVWEVERYVPIQGWVKMNKRWMKDLPSSEWIWENEWTLEASRLLVAGSDSSDVESSQSWEYAKTFDDRFHEKERKFDSVRRRKWTRRRRHLAPVLTLASTTTSVNGNSSSSPRSVRRGGVANQLMSPTRTATTSESSTASPRRHSLRGASWEEDDVDGAGGLRRRRSSLLKRRSSSFDKTMMAAALSAQDVVTTERSQRHSASLAAPLSAPLPQTAVAAANAVSAATTAAASAAAQSIRRKRDRVANALNLRRAIPTALTKDTIPAITTSVVDIKNEEEAVDTEMEVDDDDGSLCFRCFTPLGAESPSKIKSQSTETCQNCNQRVCAPCHAFYAFLVYPPPSESARKEQVCGNCYDRLVSRYKLRLEAHVGKYFIKEKERDFLELFSLSSPTNCSVSSPTAASSTWSSPVASEASSSVVSGTPAPVSTTPTNSSTNNSEHATLERYEITVQSKDESTYAWSVLKTYQDFEALEKKLYDKLKKQEKKHGSGTKQRHLKGVDYAEIQSVTPSLKQLPASPSIPYEKRLYILEEFLQRLLACDTLCQSSVVQKFLLLNNAGLGLSSSSSSSTPWSPRASGDAGELPTGAASAPASGSGSAGNAVLVENGRWKRGKWIAPELNSKSTKMRVLQQLEVSLFATLNEVFEFDGISMVRRHLFSMTRSFVKAFLSASHFRMLERQFLSFTDPKRMASMILNFREYMFPEPDAALPPPPAELSPAEFQALRQECLDAILASFPSKAVSLFGETSCENAALKLHEFVQHEIFVKNLMFSVVDEVLQHLFPDTVTYTRKTRSKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDH6</accession>
    <name>A0A8K1CDH6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDH6"/>
    <dbReference type="OrthoDB" id="129194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14191" checksum="4072A33DBE24ACEA" modified="2022-08-03" version="1">MMAKTLEQHQFDDDDSEIDDATLEALLNMPKTNGHLEFLSLTLFIEQFEQFESEFAAYNGQLLGYPMALSTKLAFLSVAKHAHASEDQGNVLLPSVLGQLDSHVLSFVFQLAGEAHVRAIRLNRCHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDU1</accession>
    <name>A0A8K1CDU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000474</name>
        <name evidence="2" type="ORF">Poli38472_014916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000167">
        <property type="protein sequence ID" value="TMW54927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDU1"/>
    <dbReference type="OrthoDB" id="430238at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF37">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="22309" checksum="788C78C5FF53CE30" modified="2022-08-03" version="1">MILDSMSGSVVFSATDLMDGIYQILMRESDIPLTAASTPSGMLWEWLVMPQGLKNVPATFNRMVSHVLRPLRHFALAYFDDAFIHSKSEDGKTAEEVHLEHLRRVFEAMREYKLYGNLKKCIFFAPEIPVLGCLVSKDGVRADPEKVESICSWPTPKNPKHLRQWLGLANYLHKYTNNYAELVRPLSQLLKKDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CET2</accession>
    <name>A0A8K1CET2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CET2"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="14"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="37095" checksum="F43F34E079D2D990" modified="2022-08-03" version="1">MVTTEPRIINALAATKPGLEVETFQYQARPLGLNDVEVAISHCGICGSDLHTITDGWGGGNFPIVVGHEIVGTITAAGSDVKHLKVGDRVGVGAQVYACLEKDKCKECATDKDPYCAKHVYTYGGTYADGQPSRGGYADYIRVLSNYAFKIPEVLPSDVAAPLLCAGVTVYTPLKAHVKPGQRVGVVGIGGLGHLALQFIRALGAEPVAFSRSSNKEQAARELGAVDFINLSNTEDAARAQRSVDVLLVTADATGQPYDTYLGLIAIGGTFIMVGVPNDAISFQPFSLIAGAINVVGSLIGGIKDTEEMLKLAAEKNVRPIIQKLPMSEANKGIKMVDEGHVRYRVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF67</accession>
    <name>A0A8K1CF67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Auxiliary Activity family 9 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF67"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437392" description="Auxiliary Activity family 9 catalytic domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="5">
        <location>
            <begin position="44"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="323" mass="34404" checksum="5D8957D26F185AEA" modified="2022-08-03" version="1">MKSAAYLSALASALLATEVLGHGYMTIPAGRSGDVYSDMTDSGACDAPAGGKVTEYKAGQEIDVEWSRNNHLGGFIRYSMVPKGQDNKANFDKNTFFYTCRETNCDLKKCNQKWCGDDAGSKDHQIKCRTKIKLPDYLKAGDYVLQWTWHSAGSSYGNIGWNTGNYKTCADIRLTTSGTGTKPKCPTFVGGDRVTKMDNKPSDQCWYFETNDLDKKEIKHGSGGEAGKEFYKFGKPREIEQCGGGASAPAPAPKPAPGPAPKPGPKPAPAPAPKPAPAPAPAPGNGGSGGFKYCGPSRPDAAALTTWCNQNCPGFCPGDMCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG35</accession>
    <name>A0A8K1CG35_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG35"/>
    <dbReference type="OrthoDB" id="167578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052579">
        <property type="entry name" value="Zinc_finger_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569:SF4">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1207" mass="133503" checksum="035821F7611C3CD3" modified="2022-08-03" version="1">MATDEGDAFAVVRTALATPSAAVLAPPFPQHHTSWESFEANLKAYSQDTYQLYVIRTTTSVRRRNHRILELASSNAAGTAQEGEDGGLTLPATTSERALIPEHWQWYSKTLMCTHGWKDRQRGTGKRSITMVRSTGCPVKMCVTLQQGGEENGWQVVVTKHMRTHNHPLSKELYLFYTENRRIYDPELLALVGGAPLEGGGGDGADQMFSDVSNARFTSQRIDILDDEDDDDNYRATGLAALQDDPVPGTVVTLPKMSTKVFDSWESFQHALVAYATATQQHFRMRSTISVNSKNGKLMDHAIKVGKSGGDILQQLIPDTQKWYSKLLICNHGWKRKSRSKVAQFQAKGKQLATVNSNACPAMLMARLQRDVHDNWRIVVNRQVVHHNHPIHTESSGGVHDEDETAGDAFMEHGVVDDGMEEDDLDHDRNESDAELADAVESLHSMEELPRESESAVAATSAAMDEVDEASEEFQQTEIEDEPVPKPMSVTEVVVRVPKLPPAYDSWDAFHEHLRQYSAATYQSYRTRTTSSVKGRNQKILEMKANASTNTTGQKQTNDLSGENARLIPEEYKWYSKTLTCTHGWKERRRGSGKRTVHIVRSTSCPVKICATLQYVDSAGSGARGTTAQGTWRVIVTKHVVDHNHNLSRELYQHYCDNRRIYDPELLAIDQTSVVPPPTSGPLGGMNSDLSHLSSASMASFNAALQSIDPTGSLMQLHQATMPDAAYIPGNTLQMQQNAAAGGALMSFGPLQLPPSDGNGNQNSVLLGGIPTSSVRSGVSMIPSFYSPALLSAPQFAMLQAAGPAIIDPSTPATSSATSQSGSLPFGVMVTATNVLCRLHGPEVNQQSVDGSIDSIDSSQECTCLRIPVVHEYRTSPATQDSSTNQQRRRPRDAEAQATSTEHGKKARKVTSVRVPGLNDSSVVQGHVAHDGGDSAMLGASTPVWGPENLLPVVPVTLEDGVSVWRAPRLKRRHDSWAAFTEYLDAYSHATYQLYRVRTTSSVNARNTRIMQQLQQQDEAPSEGEDGSDGALPLLVPTSFEWYSKTYVCTHGWKERRRGKGQRVSHNLRSTACPVKICVTLQRDPHDTTSWHVVVTKHVLEHNHEISAALYRKYSENRKIRDPDLMARAEQMWREGVSRRKIYEFLKETTHVGILMKDVHNLVQRWQQQNPRAMGDHEDGEGDEMPSTEQTLEATADHEAMLNEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG47</accession>
    <name>A0A8K1CG47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG47"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="12292" checksum="B8B4E16CD783B28B" modified="2022-08-03" version="1">MSFSARFRAFVNHPTGPKTTHFWGPVANWGFVLAALADLKKPAESMSINMTATLSMYSLVFMRFAWMVQPRNYLLLACHASNETAQLYHLQRAVRAQYLDKKDPAPATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGJ0</accession>
    <name>A0A8K1CGJ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGJ0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="433" mass="46317" checksum="1CD19FF0BEA09F6C" modified="2022-08-03" version="1">MITETLRPRRTPVPTEEPVDDTTTTSSETTDTTEEDPSTEDLSELLPDPEETDGSSDAWSSSENSYQDDSSSGSYYTPEPTTYTPEPIQPTPSPTPDQDVIAASSSSGNSSPAGTVLSVALAVIIVAMIAAFVFKTWKKRKLDAAAKASEDDVFGPPTVSIELPPTAPSDFGQSMYSQSGFGQSGYGPSARQHSSLEQSMFHTTGAVSPTHASAERPTTQSAMFQGPASTTYRLVDQTPSTMASGNLIPMSSVRSTTTRTTTTGFDHGESYLQQQPSSRMHESNSTVNSLHDSTSSDRYALGDGLGRQHQQSQGSVRLQPPVYRESDESPVLSISDLGPPTPPDGNLPSASSTALPPLPPPRQQPPPVPITPEIVDANELSLHRPPPPGLTEDDLKEETVARFTGKSSRSNGSIEFVQVVEIDEHGRPHEFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGS7</accession>
    <name>A0A8K1CGS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002038</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGS7"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="8">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="8">
        <location>
            <begin position="228"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="435"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="761" mass="85906" checksum="D28234B1C4B5F899" modified="2022-08-03" version="1">MDLQEELEAKRAEEMAQRQKTAVDHVVENLFPYAPVRVQAQRYPPSSPHAGKSYLWITVDEDEIKRRGGVAVSPVRYPVGVAVDADGNVFVSEAGSANRAGQIEGVDSPHTRKISASSIMDLATCNQVPPAPSAPKLVQSTQTSLTVRWKKSVDTTVDRYELQYRLADSPNNPWQILSVALTTRDVALDNVKCNKPFEFRVRAHNPAGWSDYSPASIVLRTLPGIPDVPRPPVAGALTNSYVSLFWSPVNNNGASPVTYTLEVRECDDPSNSFVGIYEGTECGFVPSELRPKTTHIFRLRATNAVGSTSFVESQPIRTLAHARPEIVELSPLEQSTTFDRWVQCWDPKTEQVFYFNKYTCQRVTDEPPELAAARVDKGLVAVEDTPDMVFRRKRFRFHRDLRQGMQGSALSAPLPLLLRRETMYDDTLAFFQKLKKHELTAKPKISFEDEAGIDSGGLTKDWFLQISKCALDKDRRLFRSCDHGQYEIASNSCQNTNHLKEFQFLGKFIAKAVFDRQSLDLPLCDVVFKHLLQLPITMDDLRTMDAQYHKSLVWMLENEIADVIDETFSVEVEFGNGKIKTEDLKENGRDIPVTDLNKQEYVELILKWRTEFGVKAQLDALLQGVSSLIPLASLRVFALDELRMLVNGKPTIDVEELRANTVFQGGYSEHSQVVLWLWQALREFSLEMRGQFLKFMTGTNKVPLDGYEPPLNLTKSDLDPQALPRTHTCFNQLVLPEYTSYQILVDKITFAITNAEGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIE2</accession>
    <name>A0A8K1CIE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIE2"/>
    <dbReference type="OrthoDB" id="158216at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="52005" checksum="513F78152FAF2424" modified="2022-08-03" version="1">MDWSDTASFMTFPVRKQPCDSETESTASSSAPSPLADSPYKLSLVTGATLAIEESLSDDSEQTKRSLDTMSILAIAPSELTSDERRRRRNEKERLRVRGVKDRLQSLRDDLARLHLQHDNLQQELERRVVDGYNSENRSDTVIARRYLALVKETEQLQLSKQSLEDQLRPRNLHTTAVRTMLNLESDFRLAQQFFVQSDDDRDSMNAALVIAPSPARALVDPIALFEHVLFARPFEAEEAHRLVQETCVEMMEVMERAELEESNGVYGWRGGRVVDGSRLQFRLSQAFQDVSARDLMERTWGLLTDLEGYRQIQPEALQLKILQRINNECWLIGITVNGKRIRHTVLLVARALIHGGYLVTFRTIPISPARQQYVESETGGMYVNIFSWYNFQERVNSAGERECEVIFGGNARNGDTQVLQQLRLTLLAGITRWQAAVGFPRYIFAPYLPIEPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIP9</accession>
    <name>A0A8K1CIP9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIP9"/>
    <dbReference type="OrthoDB" id="2016588at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00042">
        <property type="entry name" value="CY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000010">
        <property type="entry name" value="Cystatin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="Cystatin/monellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441750" evidence="2">
        <location>
            <begin position="27"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="30570" checksum="15637428261EAA9D" modified="2022-08-03" version="1">MMNMATTMKLTALVTTLLASSVSVDALGGTPGGWSTTELTPALQQLLLDAMTKNESNYAAELKARVCVTAVDSVEQQVVSGMNYRFHVRGCAVDSIKRAGWCAGNDAECKTKEYEIQIYEQSWTNTLQVSDITEEKSAKKEELKVEAASEATLSEEEKAQVDEWIEDNGLNKYGDKKGTMYTGGTPLFSESTGKTVDRYEYILRKHPDHPWLKNNGPGKARSSTALNLAAAETTTARSHSSGYAMVFGTLGVLTALVALVALGKARRSRRRFNYDSLSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIT9</accession>
    <name>A0A8K1CIT9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIT9"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000001">
        <property type="entry name" value="methionine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="61671" checksum="FF91B746BE22A39D" modified="2022-08-03" version="1">MRCVSTSSGDKVFITTPIFYVNAAPHIGHVHSAVLADALARWHRLKQQRVVFTTGTDEHGLKVQEAAEKTGTTDYQAFCDDVSSRFNHIFQRANVEYSRFIRTSEPEHHAAVAAFWKAIQETGNIYLGEHEAWYCKSDEAFLTETQVEDVTDPTTGEEYKISKESGHRVEKFKEENYKFRLSAFQDRLLQWLDANPDVIVPKSRHNEVRAAVSAGLRDVSVSRLREKIRWAIDVPEDPRHCVYVWLDALTNYITCAGYPTADKDAFNRVWPADYQIVGKDILKFHAIYWPAFLMAAGLPLPKKIVAHAHWTVDNVKMSKSLGNVVDPQQMLDHYGADFVRYFLLREGVLNDDGDFSTTMLEERVNSELADTLGNLVSRSTAKSFLKTGVLPCRPDEASLREDDRELVTRGQALAADVARLFETPDFSAGIKEIVFYLHEVNRYFTANEPWVLAKRLREDPEDHATQQRLDTVLYLTIDSLRMAAILLQPIVPGSSTKILDYLQVPSERRAFSHATLLSQETRVLGERVENTKSFVAFKKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIU2</accession>
    <name>A0A8K1CIU2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIU2"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01135">
        <property type="entry name" value="C1.5.6:_HAD__Beta-PGM__Phospha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="231" mass="25095" checksum="EA0570AEE906B27F" modified="2022-08-03" version="1">MAHDGRALIFDLDGTLLDMEPISIKSLASVVGAHGGGYSLASHKRILGRASAQWTAVLIEEYKLEGKIEPTDMAAQWEAQLKASYHEIGLMPGAIEFLQKMKAKGIPMAIGTSSSQAAVAAKRSHNPELFSFFDIVVCGDDKDVKFGKPAPDIFLTAARRLLGDDFDASKCVVFEDSPNGVAAARAAGMKAVALPDGRFYTEDEEKHEKFYEADEILDGLLSFDETKYGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIW9</accession>
    <name>A0A8K1CIW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIW9"/>
    <dbReference type="OrthoDB" id="123465at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051435">
        <property type="entry name" value="RING_finger_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791:SF6">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14634">
        <property type="entry name" value="zf-RING_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="282"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="395" mass="43662" checksum="BF4EBCFEC1C515E2" modified="2022-08-03" version="1">MERWLIFPDEVFRPGDVVELTQQQPHRRNVASGSQTYALYYGRGRVIHAWSSSRTHFRVRVDTLRSLKSVGLVASSATKQLDSYCDAILGLKPLTSKEIVPRARTALHCPADNALSSLSFVLWARFGDAVLGLAHSLSMIVPCLFFFGGDYDDVYIYDGPRPDPLRTPIAVPVRLLSALVRPEQEVALPSNIPGAHLLEPITSIKSLLESKLEGLMAAMVACGLSRARLKDACHSPNDTPFSFKSVDHGVLITVNRERNMFTLMFKSDENLGDRLVDDDLECGVCLQDFHEQKARVLKCSHVLCASCLQSLVRKTCPFCREPIIFVRELTSETITSMYQAVDEHPAEPTQAEQGEIPSAPASPNEQIDHEGDQDDTNKASPLSTRKTAELSSASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ52</accession>
    <name>A0A8K1CJ52_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ52"/>
    <dbReference type="OrthoDB" id="425082at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032727">
        <property type="entry name" value="CLAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457:SF4">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14769">
        <property type="entry name" value="CLAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="228" mass="25018" checksum="E26453195C289923" modified="2022-08-03" version="1">MGKATTGARGTTPSARASPVPKTAPTENPEANEPVPVAPEADAHRPPGSLLSLAELEAFENASSSSDKLLVLLDALHVQHYPANPRSTVWVDFCFGVLCFAREEARMTEYKTLVLLQIADQVFRFATTSQSDAMSSLQNVYTEFRELVRSHSIATDDSEGVERFNTSDVTQIVTFMGATFFRHLSAYQHVFQYARPTVVRLVEVEVESPLPPPPLNLATTIAQEPQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJJ2</accession>
    <name>A0A8K1CJJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJJ2"/>
    <dbReference type="OrthoDB" id="168485at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23330">
        <property type="entry name" value="P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23330:SF9">
        <property type="entry name" value="PROLINE-RICH PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="623" mass="69452" checksum="1B213C314A88A46A" modified="2022-08-03" version="1">MVARRVPRRIVAPIQEKEEVKAAHEPKQTPEEILSQAHAIGIASVIDQIAQVTTHAFEIFSDLRNEIDGIDQHLQSLARRVDTVAGALDGDARCLREIPPVEVSDRILRVPELSGAVPRRKSKALEAAYEACEPLPAFERFAEFCPSVVECRKKFSNPEFFREDWIQCEASLLQQAQQQREERRRHRKELKKQQDEDGNQQEGGGPGPEETAEMEKERLAMQQKMKFLNIRSWKERYGTGEGKELLKPPQPRDKLALGSLLEKKKRCSAQRSLSLVKEEEETKDDDTTGGPGSPVECDLTLQGFEPVASPLSHHHRAGSWSLPSPVEVQRETAAGFGAFMQEIDDPGDLEMDNIVLEPETLEPFESQEDELAFTDHGLSYYDPRASHFHDVPPPPPPPPIDVEDEEPQSSDPEDGSTLYFPPPPPPPPPPPAPPQTFSVVSDEIDLDGDDHVPPAPPPPPPPPPQLPPALTIQVLSPPPPPPPPPPPPLLSVATMFSQPLRRVSPVMQQMPTLLQEIQRRKSELRRLDVDVSFEDVESTSPRSPSPRMGLLDQIRMKQQLRPVEPPVPRYTSATTHSAISHLSAPFASSIARILERREMIAYDSDDGSDHGSAHSSENENDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJL5</accession>
    <name>A0A8K1CJL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008988</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJL5"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="28603" checksum="814D3CCE680C9628" modified="2022-08-03" version="1">MQLKDIVGIVTGGAAGFGRAFAEKILTAGGQVLITDINTALLETTGQELAAKFGKKNICWMRQNVVDMDSFHRAFDLATDHFKRDVNVLVNNAGIAGYLKFWEMNAPTEFEPVITIDLTAVIRGSQVAVQQFRKKLQGKEAVIVNVSSFAGLGPVPDSPDYAAAKAGVVGFTRSCHPLKKQHNIRVIALCPGFTNTAMGNHIDSVKPELITGMGGMMDVSRVADAFVMAIEDPNNNGRCIRIVQTGTTYFQFPGDKHLYPSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJS8</accession>
    <name>A0A8K1CJS8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011640</name>
        <name evidence="3" type="ORF">Poli38472_011642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJS8"/>
    <dbReference type="OrthoDB" id="155171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272188" evidence="1">
        <location>
            <begin position="23"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" mass="57887" checksum="680BE6EB8B7A4E6F" modified="2022-08-03" version="1">MVNLRAACLLAVSLAPLLACNAEYDVIADDDVRGVVYAEERAFVTEERAANGLPRWIGPTIGEPSDKACYRKTIRTKQCPPGYDFDKVATCWVQCPLEYPVECGMECLPQNSDCTEAILSKVTSVATAALNAASSGVFGQLAKASKGVQQGFKCGQQLLSAVQKVQGYIDELKSSGKVGSSTDEILFALSKSTFVTSDLTNAVATCLGKPVPTSAEKADDIAKMVSNIAAKALDAKSQGKNLLEPKNFIEFVSDVGLGTAMPEVKAEDVSKIKDTVTAGMGCGDAVNSVVNRVVAMVKEAKTKDASATVEALRLAVMSSDLVLKELPDAVTGCFDAKMPDAFKKRDEVLKAVHVVLDGAIEASSKEDKPLSTSEYALRIVDLGLDAIAMFDPTGIANMAKEFVQPICGPSSFIGEIDDGSADKALGLRSMEKAFMSSSGDWKKQGDGKLSITFKSVDDKDVEVILHSGGDEKAKVKVAKGQTVEWSAPLAEYGGKTLYLDRWRSGFLGIPGTGGGSLLLWVPGSSTGGLKLDVTLNPTSFKDKSLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK76</accession>
    <name>A0A8K1CK76_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009231</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK76"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000003">
        <property type="entry name" value="Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF52">
        <property type="entry name" value="CATION EFFLUX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="7">
        <location>
            <begin position="62"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="8">
        <location>
            <begin position="269"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="44857" checksum="5FEEAD8DF661A1C6" modified="2022-08-03" version="1">MSQRMSQRLSRSSRAEHDVAIANASLHDAADTPVKESTSCIDSLLQIVRGERQINHVAMALKLSLGTNIMIVLTMTAVAIASKSLALLSTLVENMIDLFVQGLLAYAGTRSGKKQDYAKFPAGTSRLEPVAVIVASSVMVLVSVVFIQEGVKKLVDGFAHDNPETPHLTVEAIVLAGIAITTKIFLVLYSRWVLKTHSSPAVEAIQDDNRNDVVSNTFAITAYIIASVEPKAWYVDAVGAIVIFLLIMFAWAKMGKEQVMQLVGVCASAEFIEEVKELCNTHNAKLSLDIVRAYHFGSKYLVELEVVVPADMTVKDAHDIALQLQFKVENLEDVERAFVHVDYKARDYDEHIVSREEDALLTYAGYSGGETPTSSRASNYTPLPQNDVEIVVASPVASGDSSVHFQEMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKC2</accession>
    <name>A0A8K1CKC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKC2"/>
    <dbReference type="OrthoDB" id="10260596at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="241" mass="27512" checksum="3F1FB5939740883F" modified="2022-08-03" version="1">MKLNIANPHTGAQKVLEVDDEHKLRAFYDKRVSQEVEGEVLGDEFKGFVFRISGGNDKQGFPMKQGVLTNGRVRLLLSKGKSCYRPRRKGERKRKSVRGCIVGPDLSVLNLVVIKQGDADVPGLTDAQIPRRLGPKRASNIRKLFNLSKEDDVRKYVIRRKFVSKTGKKNDKAPKIQRLVTPRTLHHKREIANAKLAQREKVKREAAEYSRLHAQRVKEQKERRASEVAKRRSSRKSSVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL25</accession>
    <name>A0A8K1CL25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL25"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="45"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="143"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="241"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="35905" checksum="94E4A979526493D8" modified="2022-08-03" version="1">MGQHSATITGAVSDVVEGLSSASSLSMAHLSFVASPLALSDAKERPPLYSYTFGGVSAVGAVFFTHPFDLLKVHLQTSKKENLGLVRTVRRILKQQGFAGLYQGISGGAMREGTYSTMRFAVYHFLKDDAIRKNDGEPISTAHNVILGMIGGALGGAFGNPADIVNIRMQADSRMPVDQRRNYKHAVDGLLRVRREEGAEALMRGVRPNIIRAMLLTTGQIAAYDLAKAHLLHNPVHDFEDNIQTHILSSMVAGLVATTACAPADVVKTRLMNMKHGEYKSATDCFLKVVEHEGLRGLYKGWLPAYMRLGPQTLLTFVFLEQLRKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM33</accession>
    <name>A0A8K1CM33_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003906</name>
        <name evidence="4" type="ORF">Poli38472_003909</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM33"/>
    <dbReference type="OrthoDB" id="165008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="78152" checksum="1992DE0A73CB03F0" modified="2022-08-03" version="1">MFDSISRVAAAAEHAENDKPTPVKVSLPPEHSKRDTKITWQRVLHLVHRVFVFAAAWWYIIISFQASYASMELLRGHDNSARSGTIFPFPVMTSLVGAGPIRTSSLVKTTFGDDMTPRDSSIFVVSDGQAVDACPLSPDNYLYTNEFMRAIFTTISRDTAYNITALDEATMELIAPIIDCTYVLQPNSGITGGRLFYLARERANPDRVFLVVVSLIVQQYSISAQAETGPAAVGMVQVIYDMREPSVTNYYVVAKGFPVEEMEYRVYEYLNTTPDGQWTLRSIPSTKSEFAMVLITSIREGFYIKAPSEQSNINNQVWLAPSTPSEAVGIWHFVYTPVLRDSWAWVHGVQFIIGIRLLGNLVILCLTAYNNLRARKLWIGAAFVSISTSQVLNVVLVLVSWFMNEYWSLHEYSVTVGYAVIGLPDRLIHDTVMHADLLTLYFGACGLIGSVFRERIDPLLAMALFEIGYDRQTRINLLINSHHLHAKIQAFAYNFYMRGVLAPLNGQDKISPMVVQASHNMGKRDYDYVAVCLFPVFLNLVWVVAYAILRKIYRRIFPPKVLIQQNTTGTARSGNEESILAQKRVHTLFELATGAELENRYGLVSDYDTCIFIRGTKFASADGIYSNGFVIANKKYLVQASDIWTIVAMKLLRSRFTNVYVYEVNGTTVQPTALLVYPHTLTVRDLLNLNVSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM36</accession>
    <name>A0A8K1CM36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM36"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052204">
        <property type="entry name" value="PpiC/parvulin_rotamase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43629">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43629:SF2">
        <property type="entry name" value="RHODANESE-LIKE_PPIC DOMAIN-CONTAINING PROTEIN 12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035489913" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="7">
        <location>
            <begin position="35"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="145" mass="15709" checksum="58DCCA9E09634F11" modified="2022-08-03" version="1">MTMAKKTWTFALALAALCALLSVVMMPSGALAAGAPNARASHILVDTEAEADKLLEQLTAADDLHAKFAELAKEYSKCPSRRNGGDLGSFGRGAMVKEFDQVVFEKRMGVVHKVKTQFGWHLVLTTERSGVDETEILASEIDKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN03</accession>
    <name>A0A8K1CN03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN03"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17671">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="3">
        <location>
            <begin position="121"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="420"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="ELMO" evidence="4">
        <location>
            <begin position="706"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="969"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1014" mass="113940" checksum="BE8C537CDB4540A8" modified="2022-08-03" version="1">MDALFSPALLSRLSAMVRGEQSEPESPQARQLRLQKQSKMELLAKSQRAVILEDLEHAVRGVQHFLQVKNRHSRRSASAAAASELLLHEESKEQDDKDSGNLGVQSSMMESTDDQKQLLLNDDIGVVNVLCTTLDRCVNHGLRAVESDVTDTVKFFGVVKWTCTRVDAIRQKQMLDAMQQAANDKKVCEVVTSSVEADLPRHIRGFLGAARAAASLTNVQTDEGKARAFIRQALNMHVLKTSMGMILSETNMDLLSSYYSDVALFRQRDDVKIFLHLLTGLDELAFAFLIDDRRLDQSPDELPFSTPLPRLKAQKIKKKAPKLIDPEDMVGGRVRLCEEDEETNILAEKLVSHHELRSAFNSLKGGNPLSDILKKAAQSQKLEDAAVAVLRFLELGYPEYDVFGTELLDVLCNPFLSGMARFETALGVPDVIEAGICHLFENIDTPGLFQVHLHADHVMELRDTIEELGGFHKQMSVDPHEVTAILYQYLWELPDALLTAERLDNFLACGGSSLGGNGIPSTSDAIAMDHEEKKILLKVLVNDLPWYCKPLLERLCHLVTTALEPQHAEKNGLSLYSIANCLAPLLLRKRHAQRFHEYEDSAFRKYPVGSQQPRSVRYRLLPSDDRYPYESESSRTAAESRAMRHATRDAQESAQVLSLLLQEQAFIFCDFREEMSQRREKLKDKVLLLESLRFKVEESIDTNNPVHVVLLKRLWDVLVVAQDTKGDGGENENVMIVQDNTTGGETVDVKALIDSARWRQSGFHTESPLGGFRGGGLLSLECLIFFLEEYPQKAKSMMIRNALPGGNRYPFPVACINVMRMMLKLLMLDEAPEVGSKLVMHSADPTKQTTVLKMRVAERVSRTPFWHVFDDHQAFFKLHSMAFMLLDLHWIHSGATQMGFQPVLDATRRQMGWLLEQAPQTVEEMWTKWMEVREQHATKFTPIYQNTTRTTTSSESDELVAEIQRKTQKLGQLSTTEPSSQTITDSDTAGQAISKEVAAESTSPATEVDPALAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNF7</accession>
    <name>A0A8K1CNF7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNF7"/>
    <dbReference type="OrthoDB" id="64105at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="739" mass="86294" checksum="4B41AEF523F1543B" modified="2022-08-03" version="1">MPWIRLTPEQQLRKTRWKDVHVPRVRQATRPNNAYIDRPEVLSVLQQLSDGLRQVLMTRPLRPWPWLADYLRRVCKLGHVVEQDSQVVLMLEMHKKRRVIQNTLLDTKADEVASKQLIRRIQTQQIALDLPPEELRLDDDDQVFLETEIPQEQSQWSVDVSAITLPPEQATESMDKWIATHLAPQRDLNAYFDVVLRGVTQALVGLELAGPENPAEWIVHCFQQMGASAEPPAALTTFFKTNYELLRKIEELKAAQRVMHLRRERLEEIHHTLDDELAVRARFIEKLRTCHVTVRTQAIMEGTPVFLNGQKHWVLPGSLLVPSQLTQDELVGLQRAERFLMEEDERRWKYLLRQQLEYDSCVRIQAAYKCWIAYRAYQIVTSQRHHAATILQRNYFHYLYHRAIRLPAWCVVGQEVVVAPSIAQKCATTFQFYAKKDFPTGNYKRLEGLSVAALMEICRQDEECAAFSTDGALKRFVPRKLSQLKPMSETTRPLTLSDGIYVKVYPAKTDKVVNTGIITAIPEGRFGLIRVVLDGIGITEDVPVQKLSDRWRKVRIRRHKRVEKRKPKAFVFGGVQLDERQLALETERHSDHAYDVLDVDEDEEEMARRRRRRRGEEDDPLLDFVFEDVSTKEVREVEPIHTYPDNEDRVHVINTRRQAYEAEKAVEYEAKKLASAVRLQCAWRSKRAREAFRRVLELRAKEKDRERLVADVHATHTRQHKPKAQPRRGFLSRFLGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNM2</accession>
    <name>A0A8K1CNM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Iron hydrogenase small subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004174</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNM2"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000042">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003149">
        <property type="entry name" value="Fe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02256">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00902">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase small subunit" evidence="6">
        <location>
            <begin position="452"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="521" mass="57386" checksum="964C1BFF331E8A1F" modified="2022-08-03" version="1">MASVFLGDLDDYIQPGQACVNPLFTGPTTTDANGSTTNNGVAKISLDMEMSSSDWAVEETVRPNIIRTTAKEKATISLDDCLACSGCVTSAETVLISQQSFQELLDVLASKRFKHVVVTVSPQSRASLAEHFELPVIVTHRKLVTLFRKLGVDMVIDSTSSGDFALLESRAEFLHRYRNQQKTTWTRPPSSIAVSSTNTEFVEPITATNPLQDPLRAMPMLASSCPGWICYAEKTQPNAIPFIDTTKSPQQIAGALVKHLVGREKGFNANEVYHVTVMPCFDKKLEASRKDFLDEATEAKDVDCVLATTEVIDLMNSLGVSFTDLELAELTADEILLSGVSSDASTILGSNVNASSGGHLEHIFRFAAKELFNVEVQGPLEYVVGRNPDFREVSLVVDGQDVLKFAIAYGFRNIQSIMTKIRRNKCPYHYVEIMACPSGCLNGGGQIKPKSTLVASELLANVTSRFQELQVRQPTDNPACRYVYEKYLENQPFSESARRALHTQYHAVPKMEQANPLGIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNM4</accession>
    <name>A0A8K1CNM4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNM4"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="532"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="550"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="565" mass="63615" checksum="B399981633351CBB" modified="2022-08-03" version="1">MNAKIKVVGTRGSELLRRVESVDPRVAEGLKRDTDAPATSQELQQLLEEEKRRSITDPYQCLLYDVRAMHKKGNFKGTQGDIILQRIRSLGERDEKTLDLAGFCVRDDFAELLAAFLRTKACRLTELNVAKTQIGIDGATSLARAANSTLEGLQFSTEHPIPFASARKDARTIRSVVLSGKQFNHLDAAAIGVLIERESKKLERLNVSENRLTGPSTNIFRGVSIVFDALKKGPRLVELNLHAIELRSEGLTALANTIVDLPVLEKLVLSRNNLACNSFGDKMLTGVETFCNQLWQAKRLRELSLAQNDLDYESAAAISRMLVVNQTLIQIDLSSNPISEAGAVQLANGLNRNAVLQELDLSNCAMACEAIHSLATSLRKFNRTLQTLRLRDNPQIRSAGYKELVKCASVNPFILFIDVNPAPRHESFAHKLRDLLTVNVMLRALRQDFSAFDFESLSEVLRTNFIEKLRELSEGELERLYKLHVLEHLEISRLEGIETAVSSLRYYSQMEQYAPLKRLLWVLESGAREIEVEKRPKRKEESSQRAANQAEEDDDEEDIWDYPMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNP1</accession>
    <name>A0A8K1CNP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLUAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNP1"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019366">
        <property type="entry name" value="Clusterin-associated_protein-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21547">
        <property type="entry name" value="CLUSTERIN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21547:SF0">
        <property type="entry name" value="CLUSTERIN-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10234">
        <property type="entry name" value="Cluap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="660"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="524"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="737"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="771"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="819" mass="91416" checksum="A0BD87BC6B524AFB" modified="2022-08-03" version="1">MTPWRMRASPVTRVSFRGQRVHVKRDDVFHLAGNKMRKLYWFLQQNETFFQDKHFFSYGGTQSNAMLAIAQLAHAKCVPFTYFSRGLQIKSVVDNIHSEDVNLAMAQSLGMRHVELSVDEYNDLAQNREWSRFTRPFRDKSEQEVLIPQGAAFSYAEEGFRVLADELNAYCGSFHETESSQLEGPKTFFSVVVPCGTGTSAFYLAQHLDPSIKLFAVPCVGDSAYLLDQFHALASDSSNSTSQSEAKLPEILHPTMKARFGRLSWPLFDLHHEVLETTGIEFDLVYASFAWQTLLEPANLARLLDNDSSHGGGSPRELLYVHTGGDEEDEAMSFRELRNLTEMMRALGYPRPVSMENFRKPNFELVSDLLYWMVKKYDPTSSLTEEIDTEEDRIQFLTQVASEVLVKARIRLNPKKLYAADGFAVKELIKLARVLYEASRIDVSKLAADEDDDDEVSVKSVLGSRVKDPKATRQLSSDITQSGAKLYELLDAELDVRDARTQALRFLDALSNNSDHSSEQKYLERSLKEILQNTQENVEMTERQCVELEAEEKALSAKMKKAQTDLERSEKRLKSLQHVRPAFMDEYEKLEKELERQYAIYCERFRNLDYLQRELDLHNAREMKKLAENDRSLKKLQKKFREDELAILRGEQEDQIDASLLEPADNNSKARGKATGASSSAAKGGGNNSSNPPRKSSIGNNKKPAATGKPAASNGKAAPANGAKKRATQDESGSESGSEESGDDEESGDDDDATSDESGEGGDDEARSASDSDEVSLADSGELIDNDDESGSDDGSDGGSKSGSQQSGSETNSDSDQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNR5</accession>
    <name>A0A8K1CNR5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004038</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNR5"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000023">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453992" description="Apple domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="797"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="873"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="764"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="937" mass="100423" checksum="369A7494775DA5F6" modified="2022-08-03" version="1">MAARSVLLVTVLAAFVALCQGAYWLEGIPHKGVASFHPNATTYQVFRNVKDFGAKGDGVTDDTAAINAAISSGNRCAEGCDSSTTVPALVYFPSGTYVVSKPIIGYYFSQLVGDPTNKPVLKATADFTGIAVIDANPYTANGNWYFNTNNFYRAVRNFVIDLRATPEGTGIHWQVAQATQLQNIVFEMGSTQSQGVFIENGSGGFVSDLTFNGGKLGAFFGSQQFTARKLEFNGCQKAMQLAWNWVWTFKSLSINNCQIGVDMTAAGVGSIAIMDSSFTNTPTGLLVAALTDTDPKPANSVAIDNLATNNVTTIIANSAGTVLRAGSSGKIKVDGWARGYQIDYATGSAVENTIQGDFVPFQKPSSLLKDGKILERSRPQYEDVPASQFLSAREAGAKGDSKTDDTEALQKLFDTASRTGKIAFIDHGHYTITKTITIRPNTRVVGEVWANLIAAGDYFNDAKKPQPMLRVGQPGDRGVIELSDLAVMTQGPAAGAILIEWNNADPVGKQGVSGMWEVHARVGGSAGSNLQSDKCAKNPTGPSTPKPECMAAFMLMRVGKTGSVYMENNWLWTSDHELDIKPYTQVTLFAGRGFWSESVEGPIWMYGTASEHNVLYQYQFTNTKNVFMGHIQTETPYYQSHPGIEVPFDVNPDYNDPSIECASGDSACAKSWGVRVYNSKDILIAGAGLYSFFENWAQDCLDVFPQTCQTRMTSIEGKSSNIVVYNMNTVGTAKMVTVDGIDAGAQSNATKNSFSHTAVLIKAKSSSNGVPSPTPTPKPTPQPTATPTPQPPTSPTCSALDRRISYIGNDIGVARSDKATGCCDICSKYAGCKAYTWALGTCFLKSSKGWPFPLLGAYSGTVTSSTTLPPSTCVLETGIDYLAFPVGFAKSENPSGCCDKCRSTTGCKAFSWQKGVCYLKSSKGFPVKNKAVTSGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP68</accession>
    <name>A0A8K1CP68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP68"/>
    <dbReference type="OrthoDB" id="151678at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42951" checksum="273E4C6B08563B57" modified="2022-08-03" version="1">MNGDVGGKMRKRAASALAETERTSSDSEEDHLAVVKASKDKYKPTYYARKDEIAALEEEYKALTKQLEQIEIDRRAGRHLGNPLYKNLVLRERLGEADAAVDDIQLAISSKLAEEAHNPLSTFIHLKADPATRLQTLHSLRRRKLQDALRFILERTRALDLRRPHRRTETFDTANGDHIVIQCDVTPFSRESSVKHVYDEVLRALLHQDFSVWENLGISTWSDTENLLESVVSQVRFLSTMSTGVEVEKNLTTFLDFAASGSEDLKMPYGLLVQDAVDIDDVYPYNSKQRVRHDLTLVMLVCPSPPVEGSTQPGVSLLRWSYVKLHRPECPVTPSEEDDLVDMFSRWCEVLRKVLLEYVESRRTLQTSLSLEQNVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPE1</accession>
    <name>A0A8K1CPE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPE1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="55006" checksum="01B8CB28E5166647" modified="2022-08-03" version="1">MESPSVAVYDASDKPLTPVTESSLRPKRRRSLIIGGIVVVLAVAIGLITWRATRHSSSTASGIASGEEVCDPNVKQDAGYITLPNKRDGHYFYWYFESRSNPSQDPLVLWLTGGPGCSSLWALLAENGPCTVNSDLSTTNNPYSWNSNANVIWLDQPISTGYSYGDTWDDDSDSEHDVSENLYNFLQGFLDKHPELEEREFYITGESYAGHYIPPSAHYIWQRNEELASGNVSSSTSSRKHINLKGIAIGNGLTAPSIQYAHFLDMANNSYGIELATKSELALAKNSTSMCTDLIDQCQEDKKVCIAALNECEGGVMSVLYSSPVNPYDIRKPCVTTSTDCYESTSITTYLNSPTIQSYLGVSTDKVPQWEECSNAVSSNFAYSGDYMLNHESYVAALLNSSDIRVLIYAGDADLVCNWIGNYAWTKQLEWTHHDEFNAAKERDFVTSNGSKGGVLRSYENQFTFLRVFDSGHMVPMDQPQVALEMLQRFMGNKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ60</accession>
    <name>A0A8K1CQ60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ60"/>
    <dbReference type="OrthoDB" id="125005at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33939:SF1">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33939">
        <property type="entry name" value="PROTEIN CBG22215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="2">
        <location>
            <begin position="190"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="43589" checksum="CED6A2558284B0DD" modified="2022-08-03" version="1">MQMRKKLESGEPFYDEEERDRAMEVPPSFAGDVRDAIFDMYAAKQHVTLDTLLKTLQDKRVTRTSGWKWSRSTLYRFLTDTMHYTYGKRRTYYQNLKENVSIAAQRVAYIKKVQEYRAEGRPIFYQDETWVNKNMTPANVWLDDEGQGGRAVPQGKGERSIVCHIGGRDGFVDGAKLISRGSKALKDSDYHTEMNSSVFLDWMRRKVLPAVPSRSVIVIDRATYHTTLTEQTKPAKSTFRKAQLAEWLVAHGVVHNGMRTVDEYMTMTKPELGQLCKENKPKPEYEVAVTAREFDCDVLFLPVGHPELNPIEMVWSYVKSYVAKHNTDFSLSEVERLSHAALDSFDSEAWQRYVDHCVKVERRYLELADDVPLDMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY6</accession>
    <name>A0A8K1CQY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY6"/>
    <dbReference type="OrthoDB" id="5949092at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36453:SF1">
        <property type="entry name" value="RIGHT HANDED BETA HELIX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36453">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433732" description="Right handed beta helix domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="938" mass="101715" checksum="103E64BD9732D02E" modified="2022-08-03" version="1">MASPARLALISCWFLVFEALGNAAAPAIDLYISPSGSDNAPNDGTLSLPFKTLTRAQQEIRTRKAALGAKPSPPFTIFLRQGRYELDATLEFSAVDGGDSADTPITYQAFCDPAVEAAQQSVEPYPYASHLATPPRLLWNGVGDRAAWKGPVDPFYQMGIDRAKNSLLIAPTPAPPIANMDIGPLCVDKVGQGHTCYTGTLAMCVAGCQDSCTRHLERKMYSAAFYSEFSHLFGKNLEKEEDCIEICSQSCRACEDVTISGSKRFQPTTWTLDRTITTAVNSVTTTLSVFSTDLSTYLPATPHFIEQTDPPTVFSTLYFNGVQLPRAGYPNCVVQSTPSTALTPFTCTFATPSVSSKRGVLAFDPTKFSARVAQWTEASVASMVVELRPNRSSHANLLYMASSVDAVKNEITLGAGGSHITPEIFKDGVDLSTASLAALAGFRIENVLEELDSPGEWYLDVATKRLYLTPLDSTTATVATMASTVLEFPWLRQLVRIRGSQENRYTATAHASEQLLETDSSVRVRNLRFDQLKFTGTQLLATDLYDAMPSTARKTHPRWPVARTGAFFMENVENIVITHCTFNQLGGNAVIISGESDRVQVDHNNISFVDSSGIVIVARVASQDNSFHTPVLAHTLYSRSAILASNQIHHFGRRVAHSAAIMVVAAQQTTIQGNLIHTFPATKDAATNYVIENPVGALNADPPLLFRRIDPITIPSTYAQSLSTLYTITVPLTGFNIPVIAKLIGAPECPSGTGRIGSLYNELQPFTYTQCSGCCSFHDSGARIRIAGAGTAWVDAKRDVLVRPGDSIELSAVSSSLFNAIVDVYLAFHIVTPNRIIELPARAKWQILTRRCQYTETTYDATCSGPCTSSSPTTGCGNTNIAIQQNAALQCAPGYEADLSTHVCLGPFEAFVDCDGSGVFKSHRYYDCSIRCFTTQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRF3</accession>
    <name>A0A8K1CRF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000193">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="29"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="491"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1811"/>
            <end position="1879"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="616"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="760"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="908"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1041"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1412"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="507"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1811"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="117"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1879" mass="212505" checksum="D4804AA93A70D3A3" modified="2022-08-03" version="1">MEVATTPVPMDMTSVTSDTPALRQGEAENIAVCIRVRPLNEREVKHKDAPVLRTVNAMNLISVTDSDGQPLPGKHNVFQYDHIFDPQASTRVMYDRVAQRIVRSTLDGINGTIFAYGQTSSGKTYTMTGTGGSPFEDEEMTVPSSKPESMGILQLAVEDIFNYIEQSTDRDFLLRVSFVEIYNEVIKDLLNPSEKGNNLKLREDPRKGVYVECKEEIITNYENILQLLHMGNQRRTVGTTAMNERSSRSHSIFRIVIESKEKSASRRQSEEDMNGAVLVASLNLVDLAGSESMRNTAAEGMRQREAGNINKSLLTLSRVINSLASSGAGAQNAPFRDSKLTRLLQNSLDGNTRTLIICCVTPSERYIEETKSTLQFAQRAKNIQTSAHVNEVLDDQAQLKRLKREVHELKKMVNSEAYNALKAENEALHNEQSKNKSEIKRLMGLILSSSSIREVSLARKTKPRAKRTRETWCPGDFAADMKPIREFERLAFGPSSSQARKRHSDGDSSANFKENINPQNPMAISREIDEERSHISDRKRRRVMQESNELQTVVQRLENLVRRRRGVAPQDDSTISEDSNVDTDTDVEGRIQSLVSELEVLMNLSSPTDGDLAGENELLQMAVEELKTRLSHANSKLGENEAEALKTLQHEQAARADLQAEVESLRFELSQPSGIHNESSDPTSRLEAAIVEIEELKIAKESTVTKLEDELRRKSDELSQKTAEFAERESELLREIASLKISSVEPEREEESEKTLKKELDAATAACAALTVANQRLENEQASVMDAMVALEEQLQQTAQYQAELESQVKSIDEEKTILAEKFASIKDAHSNLQRELDQLKSTTSTGEAVHVIENSSEVEQLKLALAERDVLIKQLEASEHEARSYKEFLQAEMDEVSESTAVLVADKEELHAENMRLRNQLADLKREVEKALQNQLAIPDELVGEIDQLQEGMEKLKAELNAKKTEEKMWTVQAQKLGQQLEDYTQELAKVKGEKATLTEKVKALDQEKTVWLQRGATSDDLHTEISRMREERWGLASKLEESEGNFLRERRELQRIQAEMREVTESLRDENASLSDKIVEIAEEAQRITSELESVLKKNNELEEQVRSLDELGSNGHHSSGKATSSAIVIALESELEAAKSAQANLVEELSALESQLMATTEEKLSLETSLDRVTAEVEQYKNAVRSAEDKLLGAGNTRVANDEVGGDVEQLVEQLTAEKKRREKLALDVSSYEEAMVLLRDELNMKSDSLRALEISIQEHSSIRDQLEQEAVKLRTQLQRAKEEQEELRYQSQQRLMSTDAKQSGLIETVQSLEQQLAEAKSAVHKSVQEWELRAEQAEDRANALTVELTQERSEKRELMDQISRLESQHRDLFSELEQLSAAKHELGQMEQSLKSREEFWQEREEELSRKASFEMSSLREQLQESQDELEAYQKYADEEIQKLRLSIEQNDTEMLEMNNTTKQREESLLKRIADHEDMVSSLRDEMEHLHVELKTERASAEEIRAQHSERLEAGAALVSQLREDLEEMARRCERAEADQMGSSEQLKEMKSAMEKLEGEAYQHRNELEELSESLKSAQMEAMHYHNQLVEAQLAKEELEKVSETQKKRIEKLEKVKMTTETLELFRKLKSDRQELQLQVKKLEQEMDTLAKSRDQFKEASEQQHARALQLKEEEIGLLKDHVDELGLALKAEKEKAAEIRSEMKSVVDDMMDKAQQEIYDMQAVVKEKSDQVVDLEEKLSALEKEKVAMKEHRTSKESYLEKENLELLVENRKLKKRLESVASSSSSSSYRSRTMLDDDVAAFEASAKAASAVLAEPPSSASYSLGATVSEPKSPVAEEKNVPASTSSAEKPGLGGFLMPSSQEEEEARPSCSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRY4</accession>
    <name>A0A8K1CRY4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRY4"/>
    <dbReference type="OrthoDB" id="98532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="30163" checksum="E3A7681B34F288C5" modified="2022-08-03" version="1">MPVDATVVLERETQLRDAIAKYETLVTLATQSKQHVDFAFVWPREIRLYLADCLVTLARLKRLAATQGTEENKDDEIPYLLARAREIYTDPELTNSKMCALGRIHVLIEEAEALRQSEHAPEALATFANAIELCRNVGDQETESRLVRVTQVMQLELNATAHLDTVMSQSHTPESEKQILTEAFQRLAGNDGLLQNDQLPNLAQALDGNSTKAFDTTEVDELWRQLMRCKPSGSTVEASSGIDMATLWCWWMSEAKYAYQRRSRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS63</accession>
    <name>A0A8K1CS63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">PAP-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS63"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="281"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="9">
        <location>
            <begin position="508"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="69664" checksum="49BAE975545B1ACD" modified="2022-08-03" version="1">MAKMEHEEQAAMTEPPRKRARRGKRKSKAERLARGLNAVDTSESTSDARNGAVTMETLQSLLDAPTSTSSIEWDHAQSMALRLGSSEARCLMVFKLLFDRQAPRAVGHYAKRLHVTSEELLQVLESGRNDAARAIQVAKLLIETETDVVSNEMRLERFILPWLEHSRVDPSRGSTCEGEENDDDDQQNDAAAASQAVASSFSTALRLVLQRQTKFPDQQLALQRLLLRALRESLTPKASWSHPTIAFTYAGALLPLLQQASESSGSSGVVPSVWEPNALAREQMRRLEIARRVETQLQMLWQDARVLVFGSSVTGLLSPDSETSTQATDDVDLCVVLPSLPSFQHDTASTVVEMKEHLGMYISDVMAVSGARIPIVRWVDPMTKLQCDLCVNNLPALWNTQLIRCLVRVDDVVRDFALWMKQWHRAKKPLFGASLSSYGMLLLVLHFLQHRGVLPYVDCSTLVPPTATADEATQALNSVEIEDIESRVRAALHTQTTGSTIPTPSCWSLIVGFFAYYGAGEFDYEHDVVALRCASLCKRDKAWIRKSWRYALSIEDPIETERDLGTLFTRATLTRFRCAILESSLIIADCVEENEATLESSVEKLRSILERILQPVGPFDPEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT26</accession>
    <name>A0A8K1CT26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT26"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="432"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="523"/>
            <end position="530"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="98453" checksum="7D8870828EE85B78" modified="2022-08-03" version="1">MVKLFCAVVGVGSVFPVDIDISRTVGHLKDKVKEKKPGLIHFDADLLKLYLAREGDTWVNLQDDELEKLKNGEISDRIKSLIQEELLLDETARLDDDDYFRKTFERAEDDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLESESLQDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNWLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKGIDGRGWKRPPVYKSPGTATMIPQQQWRGEGENMDKRTARKVHADQFQSTIREIRAEYVKKASQEQPAETPDAEMASDQIHVYVRKRPLLPHEVKKHEFDVISALGEREIAIHECKMYSDMRHKYIVTHRQRFSQCYSEQTETETVYEDTTKRLVLHAMGGGKAVCMMYGQTGSGKTYTMGGMMDYIALDLFTENVGSVDFVVSVSAIEIVGTKCFNLMRDRAKVLVCEDGEGNINLLNSSETSANSATELLTVLEDVKNQRTTEATTVNSQSSRSHLAVYINLRHRSIDETPGELYGQLVLLDLAGSERNEDTFYHDAARRKEAIEINKSHLALKECIRAIGSEGSTGYVPYRASTLTRILKDCLWSRDSRASVIATISPLSIDTEHTLHTLLCAGQMLVDAPLISTEKTDVSEHGEAKPVVLIREWDATMVREWVSGLRNGEFAKYSSKLPTSLDGRMLMRFTVARFTQVCGGNAVDAGHLFKAVRTEMTNQDKLVKARRERIVARTQKKSGLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWJ3</accession>
    <name>A0A8K1CWJ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWJ3"/>
    <dbReference type="OrthoDB" id="1718410at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="133" mass="14974" checksum="F76E13C1558D292C" modified="2022-08-03" version="1">MQRTGARGGRTITKAILDINDAPIIFFSKYPDMTIINKAILYVRKNEQTSNLRVVHMYNDDVDGGVESGASMETRKEFENIIALFGHIYPKLKIDFVSLYGLFEPATVKWVSETMHVPTNLMFIAQPGDKSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB99</accession>
    <name>A0A8K1FB99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB99"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37524">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37524:SF2">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE FTSJ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="1">
        <location>
            <begin position="188"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="351" mass="39333" checksum="0D532CD06F380BC5" modified="2022-08-03" version="1">MDAPRLSVPCVAIHCEETQLERFSVRAQSLLVNNARTRVLTVVSPLVYVQSETHSTDSTALYQQNAALRRAIDREMGQGRIAAHRIYQLDGCCSDPDWIPQSQVFRDECSTQNVVIRVVAHPRQLQSKMTQVLVEHGIQTHPTQYTHELFVTTQASTSPLFFFGIGKRQPITLVDDSLQIRFRSEAPCRAFFKMQESLRHVSLCPGDHVLDVGASPGGWTECLVDNGARVVAVDPGELTIETTNRPIVHLQMLLEDALEQLRDMERFTMCVCDINVRVAQMAALILQAAPLLKPQATAILTLKLGKRPTPQAVDGAFEQVQQILAPAFTDFRLVWLHANTQNERTLFATKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCJ4</accession>
    <name>A0A8K1FCJ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCJ4"/>
    <dbReference type="OrthoDB" id="425490at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14811">
        <property type="entry name" value="bZIP_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="118"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="45203" checksum="8F158AB4FD83F804" modified="2022-08-03" version="1">MNMELTPEDDDLLSYFLSADVAAEQLTQPKPEPAAAYTGLGGAAGNASEFAFAQPMAMTQDGRAFGGAPSQGISGSGGVTTVAAMQGAFHAGDAAMMRGPQDDDANSTTASASGLDSDEKRQRRLARNRESARQSRRRKKQYLELLEEKVSQLTESIDATRASHLDRADDALNAVRSEILATLAKELSDDAGEGAATEKIRQGIQLIRERFGPNSLERNAVKDYNFRQLDNLLLPPYCRFLLWLSIQDDSFFDEANGLSAKAGVPEIPEKKKTPTVVKKDNLWQTLISELALTYEQDEKLKSLYKSGDSKASKLERRRVALAVAYLSKLKHSLEERAKEVQTQTDTIHSILTPEQSLTYLRWVDMNQDHLASFVDKSTTISSSGAVSSIQTILKKPDRELTVEDVTALLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCP4</accession>
    <name>A0A8K1FCP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003346</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCP4"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="121"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="164"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="58508" checksum="11A7B5B9F38C062F" modified="2022-08-03" version="1">MSFPGGKAPERKNYFKKTIDADEIRRRRSETTVQIRKTVKEDRLNQRRRMGGADGMGMVAAGGAAGENLEMSLSQRLSELPLMVQGVHATEREVQLDAVTKFRKLLSIERNPPIKEVISTGVVPIFVQFLQRDDFPELQFEAAWALTNIASGTSDDTAVVINHGAVPIFVKLLLSTNDDVREQAVWALGNIAGDSVECRDMVLRCGALRPLLGQLTENAKPTMLRNATWTLSNFCRGRPQPQFELVQPALPTLGQLIYTNDEEVLTDACWALSYLSDGTNEKIQAVIEAGVCRRIVELLMHHSPSVQTPALRTIGNIVTGDDLQTQVIINLQALPCLRALLDSPKKGIRKETCWTLSNITAGNQNQIQRVIEEGIFPSLISFLSTAEFDIRKEAAWAVSNATSGGSAEQIMYLVEQGCIKPLCDLLAASDAKVVIVALEGLENVLRVGEGQKGVGEFNPMATLVDEAEGVPKIQALQFHANEDIYQKSLKIVETYFQGEEEVEQPLAPTVDASAQQFTFGATGGQPSVFQFGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCZ8</accession>
    <name>A0A8K1FCZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_013784</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCZ8"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418722" description="glucan endo-1,3-beta-D-glucosidase" evidence="14">
        <location>
            <begin position="22"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW55022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="33894" checksum="05932B1C0270C71A" modified="2022-08-03" version="1">MKSFFLALVATVCLSVSSVQAKGICYDPVHGNTNVNADSIRIDLTRLRDAGFKAVRTYVVMHSNQNLGMMIVKNNMNASLTVPFVNDRPGDSEIHIKGAIEAAKHRNGAARVTHIWVGNENLASVNAVPQQMFDFITRLKNSVPKDVLVGTVQRNTEYLDPARNGIGRWKELLDRCTIAGINIHPIFTPNTPADKGVSVVNAQWGQLFSEDMKKRFPGLTGKLAITEVGWPSGGSMNGNTGTKAGSLTFMNAYADWRKRHVDEQRSFYFQAFDQPQRNDGPFEKFFGILESNGNNKFTTFNFKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD24</accession>
    <name>A0A8K1FD24_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD24"/>
    <dbReference type="OrthoDB" id="166759at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442218" description="subtilisin" evidence="9">
        <location>
            <begin position="21"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="181"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="468" mass="49275" checksum="B15E8765BAA3601D" modified="2022-08-03" version="1">MLTKAAQAVALAAFCCAVTAHDAPTAWNETANAASAHRILTSAANGGLNVIVTFKNGTTAPLKHVNSQKFHTRGARLTEIRRSLEDHAKKTQHSVFDLLQKGTFMRSERFWISNQLYVHGATPDLVENIKKHPSVLSVELEAVHFLVQPVMPVGTSDLIVPASWGTTKIKAPVAWINKVYGADVVVGVIDSGARWTHEALKDNYRRSFGWYDPEWKTAEPYDLSGHGTHVTGIIAGGKGVGVAPKAQWIACKGCRATGCHTADLLSCMQFMLCPSTPDGSLRDCTKAPDVINNSWAGNKGITTFNSAIEAWKAAGIIPIFAAGNSGPSCGSVLSPGDQPGVITVGATDATDMVASFSGKGPTINGLVKPDVTAPGNSIKSTCVSSDTHYCAMSGSSMATPHVTGTVALLLGVKPGLSYAQVRQALTQGTTMAVRPAALVCGRVAATVFPNNQYGFGRIDVTKVLAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDI4</accession>
    <name>A0A8K1FDI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Auxiliary Activity family 9 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDI4"/>
    <dbReference type="OrthoDB" id="119923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035440938" description="Auxiliary Activity family 9 catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="2">
        <location>
            <begin position="44"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="459" mass="46624" checksum="0D11D62A81D2D454" modified="2022-08-03" version="1">MKLFVLASAVASLAFLDAVSAHTSLKTPVSREGGREIVEDVNGSVGCKKKMAPGGPVTEVKAGSEIPVEYYRNNHIGGFVRWSLVKKSDEENMDAFEKGVFYYTCRESGNDCNPRNGKPYSLWREAWDGVDTFIIVCGDKIKIPDYLDDGEYVLQFTNFGTGHSMQDPGLATPTYRSCADLKITGGSSKNPRPACPTFVGGDRATKNENKGNDVCSYFQTNEIPKANALFHEKDQSKLDKLYMFGKPAEYVKCMASNGGNAATSSAPAPVTGGAVPALAPAPAPVPASSTATATAPASAPILAPAQAPVPVNAAPTVPSTTMIIDSPGAQTMLTAATAATAAPGTVHAANVTNLAVSTAVTATGPSAAFGSPATAPLAVAAPVPMSPTLPLAKTAPVAATAPVVPAMPAAPAAPLAPTVLATTATVAAPAVGGVTVPPTAGIDPLGAPVAPPAMQGVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDN3</accession>
    <name>A0A8K1FDN3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDN3"/>
    <dbReference type="OrthoDB" id="167703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="501"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="302"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="558" mass="62508" checksum="62F0F75706376A61" modified="2022-08-03" version="1">MQFSELPRRSSCPALRVDADECNHELLEHLDGVGREELSSFSDDVMDGQNTSDNNAELHNDVTWCECKDEGNPESPVQTKKLLPLRMEHFVRRRLAQVVQELSEEKENLRLAASAGSSLLEQLSVARIEMNNLRDESEARKLELDTAGQENQRLREICAKMESELRKYDAAWAEVEYPSPKWEPSSSKLATITSPGKQTILRAPVMTPADRDASCQMCDKREAEVVELQQACGELKRRCLDLELRNEQCQTELLEMSTAYKKTERSLKRVQADHAKALTDVDFMASQIKIMKDDNSSLVTSRDNLRGSNRRLQAENDALSSSLEEHKTMIEALLTDKRAAVLQATVLESRISSLQIENERLRLESTRQQNQLQRCEAEAADLMDCAALQRHVMDIEALLEDANRQLIEVRRENRLLSSRLRTSNAETSGMAVHRPEQTPMTVAEVLAMNPAVVEPLASSDMSCGKEQTSCADENKYQLRKRSQRRPPSIAYVCTSTGEKMRLPTLEAPSRRRSSSLKNRGSRGGAGNSVGSDEGVTAPVYLGLSLLACATAVRYIVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDT3</accession>
    <name>A0A8K1FDT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein kinase ATR</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_008570</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="16">
        <location>
            <begin position="1236"/>
            <end position="1896"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="15">
        <location>
            <begin position="2001"/>
            <end position="2328"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="17">
        <location>
            <begin position="2352"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1347"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW55922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2384" mass="270021" checksum="F40A8D8062644B8E" modified="2022-08-03" version="1">MACRGSRPGTPNMAMDVEGGKEEKREESAQVSMDANGKKDDRVDVEKLLPTLHAHKRQHEDDTYPLSQPSTTKRCQEIAGRLRLTILRLLRKVAKAPDDKVAEILVGACEAIKLLVEGELCPHFAGIFLDFSGGANASRPQTVRGSPSVEPAVTTLLYLMTYASQVRYQDQQATVIDAMATLVLLMQQSDFYAFLHFFGDAVELLEDCVLLEGCLERRGFQMSPGKASIACFLDTAIHAYHSTSGTLGSTHTEILCGCVPVEEQSRVFERKEQLKTLLPQMKVASLRDLTYLRKAIEHIIIKITVYGQLDLRGNASKLVDFFLESLSNPAKAIRECASQQLQVLVNHEDILDELLVPSSGTVGLMERIGDAIRNSQDGSILTRSCIDILGTAARGKSSTNASSRILVWGLLQLAFVWIDYYSDDAKKGFSAAAFDQIQRTMSYHQLSWRKMLLEYPGEVYFPLVDNLLRTRSVKDFVSTFMGQTMTKGILTDSAAYVLPHYVIHRDEDMLNQFVLECNQGDGDVEMEDVDSEAHSENTSIGQLLQENISSVFKELIMHQVQEGKKEDHMKDWNFLFKFFPENFTIGDVLSLRQLQVLSAIAAELGGERHHHAKLAFHEISQYVIQGTRVNNAEAGLVMPRQFFLAIMTTFGNTISDKSTQLAMRIRTVKSIDRLFSIFKRPGDEAGASSVLDAFVPKVMAILKIGMADPSLQKYSIQAWGNFIRMLTTKALETNFISIVVSVLPYTRLSDGDSETSHQKNLDKQRSPREYTREVAIKIIRYLFVEKRDDLVKAFPKVAILPSTPDLDESSAALMSVVGDPARLNLRDILQNCVSYINHWDMAVRERILDHLYHTLVARTSELEGLVQSEGDLFVDPVVVETLVSILKVASLDTDTNIRLLCSKCLGALGAIDGARMPFNFLHSKSDKIDPRSETQAKEKGDTRSELPTMDLALVLIEDWLVKELRAAPENTDSVAFAIQELLKFLSDLTLDPQHSGQQVDDTESAVRRSKVGVGPIPDSLKRRFDKKEIFQFVEPYWSTNYSVQTSRLRESDPGRDDSTFYEDYRMSYEKWLSTWCRRLIKLSQAPERKIFNACRNILFECPQIARFLLPYLIQNVLRSGRPEVYEEVKREVIAVLKDNGIIDDGANGGYSATQMPYEGQDDARERAFADYASRHHQCAQTVFSTIDELNEWVWKNEKKRFASSASSRASGDVPSELDDHEKENLEEFLKDIPSQVLSSAAFRIRAHARALQYFEVYLRQQQAPPSSDSLHAGISPVELSLVAKHATYLQQLHSSTDEPDALTGLATLRRLHEAYRHADIFTERRVDGEEWTSLTYLLHQVVDFEQLAQWEDALACYEQAIQEVQSAQANRAFYSKEFPPDGHEGVNGVDSGFPTDPHLVKPDLYSGIVRCLIQLGRLESALQHINGIVTQEPQFVGTLYPHALECAWRLSRWDLVSDLLNSERDTSLLASSFAQGGVQSRLRNMEVSQLTLVRVLKNFHDCDRVALSKNLQEARLEIMGPLAAAATESYERAYPLLHKLHFLHEVEQGFSWLERSKSLEPDDRSHEWTKQCPWDSRYEIMSASVKFRDPILALRRMMLQEADLPGEVSRIWLQYAKMARKEGYIRTANSAVMHAEALDNPYASLERAKLMVAQDRVHQALQILEPVDIDATKLDFNVEDPHFCAKNLLLATNWMQESGQRQGKKVIERYEAVIKFDPSWEKGYFFLAKYYEYLLNVRHPELQSSSSAGEESSLNLDDVFHSHLINLIKNYVLALSHGTKYLFQSMPRLLTLWFEFGELLQSGSRTSSVNKTMRSIEADVNQSNTEEQVLSDITRIMQNAAERLPAYEWLVCFPQVTSRICHPNPVVVDGVKRIMLKVLSTYPTQAMWPLLGLSRSLNAQRRARARDIVANAQRQFVSCGQNEVANSFAEGMRLAEELISLAGHDPGNQRRIQIRLTRLRAQILVPIQATLNTVLPSSGLAPGDERHAAFSSTSVVYIRSFIDRADVMMTKEKPKRIVIHGTDGKQYPFLCKREKTGDLRKDARMMEFNTMINKLLQKDREGRKRKLRLRTYAVVCLNEESGLMEWVPNTRAMRQLIGQIHKTERGLIPPVRLTQEIKERYLGMQKKYADHIPTMATYYRRKILSLPVFTPRFHQWFTNNFADPTAWFEARLMFSRSAAVWSMVGHIIGLGDRHGENILIDTTNGECVHVDFDCLFDKGLKLAKPEIVPFRLTPNMIDAFGITGYEGVFRRVCEVTMGLLRENKETLRSVLEAFIHDPLVEWGRRGKNTQGSTTGTTGRSIAEITSDRSKEETRVILKAIDGRLSGVYNLGEAIRPQITPAHRKLLPENETLPLSVQGQVDKLIHEATAHENLAQMYIGWMPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEW4</accession>
    <name>A0A8K1FEW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24188">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24188:SF29">
        <property type="entry name" value="GH09064P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="59"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="59"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="59"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
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    </evidence>
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        </source>
    </evidence>
    <sequence length="2300" mass="249791" checksum="90E76FCEFAEBF487" modified="2022-08-03" version="1">MIAASNGHADVVRFLVEQGADPRTKDMNGWSTLMSASQNGHVDVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASQNGHVDVVRYLAENGVDKETKDVDGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASQNGHVDVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVDGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAENGVDKETKDVDGWTAIMSASQNGHVDVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAENSVDKETKDVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVDGWTAIMCAASNGHADVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRFLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAETSVDKETKDVNGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASQNGHVDVVRYLAENGVDKETKDVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVNGWTAIMCAASNGHADVVRYLAENGVDKETKNVDGWTAIMCAASNGHADVVRYLAENGVDKETKDVDGWTAIMCAASNGHADVVRYLVEQGADPRTKDMNGWSTLMSASRNGHVDVVRYLAENGVDKETKDVDGWTAIMSAAYFGYLDVVRYLVEHGASAMVKSMRGATAIMCAAEKGHTHVVSYLVEKGVDVEAKENEKGCTAMMIAAQYGHADVVRYLAETGVDKDTKSNNGDTAMMIAADNGYADVVRYLVEQGADPRTKNVNKVTALMCAASNGHADVVRYLAENGVDKETKNVNGWTALMCAASNGRVDVVRYLVEQGADSRTKDMYGRNVLTAASQKGYVDVVRYLVELGADPRTKTITGCTMMMLAAQNGHLGAVRYLVEQGAEMGAEDFRGWTATMLAAENGHVDVVRYLVEQGAEMEVKDPTGCTMMMLAAQNGHVDAVRYLVEQGTDIGAENLRGWTAMMLAAESGHVDMVRFLVEQGADVKMKDSFGRDGLIVAAENGHVDAVRYLVEQGADVEAKTISGRTAMMLAAENGRVDVVRYLVEYGDNKETKSSSGWTAMMIAAQNGHVDVVRYLVECGAEKAIKDKNGVTAMMLAAKNGHADVVQYLVECGAEMDTKDLNDFTALLWAATSGHLDVVQYLLARGADGLSVDKDETSALLHLLMRDDINEVRLHLISKLLLERGLHPYQLNKHGQSIKVVAVKKNFHGILALIEEYMSKPKQCEPEPEDQSWLIPHSEIVKTHTAAIAEGGFGCVYRAEWARIDVVVKELSGVEMRRFLKEVNVWRGLRHRNVVPFYGANHRQEPYFIVSMYASNGELGPFLKREKAEGRKVTWRKLQEVATGLRYLHQSEIVHGDLKGNNIVVSSNGTAMLTDFGLSFFESGSCSYIKSMKNTLGAMAWRAPEYANMTVMTPTCKSDVYSLGMCIIEAVTGENPWGGYTSEEIRCFLRDGKIRVERPSASSMTEDQWQLVQRMIAFSPSDRPDLETVLAELAKFSTEELEMENSALCPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEY4</accession>
    <name>A0A8K1FEY4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEY4"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="20"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="511" mass="55528" checksum="0961870985A01E8C" modified="2022-08-03" version="1">MTTESLPATYRAYVIEAFGDAVKNIKLRSGFKHAPLTPTQVRIKVHAAAVNPVDFKMVELGAQFLESHPTTEDPLRFGFDVAGVVVEAGKDVTRFKVGDEVYAMSNYGVLGAHAEYYELDVKYIAHKPKNLTFREAVGLPLVGLTSYQALSFYGKLKAGDRVLILGGSSGTGTVGVQIAKALGASFVAATTSSRNLEFVKSLGADQIMDYTSEKWWEVLDPHSIDLIYDCGAEPLSCNDVAQKVLKPDTGVFVTIDAFAPIDKAILGPKIHQIMVDPNFTDLETLTKLAEAGKLTVPIDSVYKFESLHDAITKQKSNRVRGVVVETGEDVEDAKVGDEVYAMAKIGHMGSFAEYFEQDVQFITHKPKNLSFSEAVGLPSVGITSYQALEMYGKVKPGDRVVILGGSCGTGAVAVQVAKALGASFVATTTSSHTSDFVKSMCVDQVIDHSSQKWWEELEPHSIDLIFDCGFEPLTWNDVAQKVLKPHTGTFVTIDPSRRSMNRPTVLTSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFS9</accession>
    <name>A0A8K1FFS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFS9"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03571">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="20"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="662" mass="68459" checksum="E68BCB070C9716C6" modified="2022-08-03" version="1">MDKFTLDRLKNVVDEAKNAVKAKLGTDVEKKLEEALSNKNWGASSTLLNEIAQLTYDYESYNVIMTKIWEAMDSHARQWRTVFKALTLLDHLIKNGTERVVENARDHMFKLRALSDFSYHDGSADKGAGVREKTKQILDMLNNNDLIREEREKSRKMRDKYVGIGSVGGGMGGFSGYGNSSSSYSGGGGYSGGGSGGYSGGGGYSGGNTGGYGGSSDRYGEREKSYSSRYADEQEDRSGRSGRREKDRDESSESEEDTSTRRRTGSRKKASKKKDEEDAPQSKGPSAAPSLLDDDFFGSASNAPAASSGGGGFDPFAPAPAAAAPQQSFNAFGAAPQQPAQPAFDPFGVPAAPAQGAPSAGFGAFPAPAPAQQPGGMGGAFGQPMGGMNAMGGMQQPMGGMNAMGGMQQPMGGMQNPMGGMNAMGGMNTMGGMQNPMQARTSSNPGMTAQPSRTPSNSKPANSEPKRNDAWGAGSNLFDLNNLGPTSSSSANPGMQSRPGGSASSQNSFSGLDTLAGMPSRTGSYGNSNMNAMGGAKPGMGGMAMGGQMGGMGAPMGMGGMQQPMGGMAMGGMQQPMGGMGMGGMQQPMGGMGMQQPMGGMGMGGMQQPMVGMGMGGMQQPMGGMQQPMGGMGMNGGFGGGMPQQQQQQQQQHNPFGSFGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG64</accession>
    <name>A0A8K1FG64_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG64"/>
    <dbReference type="OrthoDB" id="165936at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="390" mass="43827" checksum="27CC721D8382D33A" modified="2022-08-03" version="1">MRREAALRGVPTPVADDLRYNMWIPASVLTATFKDTEILTSLGQSSQPSVWMDNCVNGNIRDFKCIKNAGISFVCTDRFICQKLGGTELSICGKKFKVQTYSRYTHWYYVDLTRLPDETSDGEIYDWFAEQGAPPVYITPTNSIRGLHSRSRRVYFPTKTTPACFILPGEKPLRQIGFRAGFCVVNHRIRAYNQSKPPFLEALQTQRRELKKQEKNEKNQSKSKPAFSSSLQSNIAKSSTEKEVKEGDDDSMEGDSEYNPDDDEGGDGGDFPMSSSSEKSKSRGSSFDSDSDPHSDDEKDDGKVVVNPATIWRDVSKPPPNFPSPPDQRSEITFFQVLGQRHTLFPDAEIFSAKDNFKVKVLPISQNSYPVFATVNPFEWIASGETDDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGA4</accession>
    <name>A0A8K1FGA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_003523</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000003">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="855"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="902"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1217"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1258"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1290"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="51"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW57598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1342" mass="148460" checksum="12B2D003AB2253D0" modified="2022-08-03" version="1">MTQEAPRLSSAEIVAVTTELRHRQAARRRSKKDGKGGKGQQDDAKRELVMEEHKQSIAEVIADLGTHLTNGMSNDEVDRRLETEGLNRLSPPKQTPEIVKYFRELTGLFSLLLWFGGLLCIILYFVQGDPNNLYLGIVLFLVVIITGTFSYSQNRKSSNLMESFKSMMPTMSTVIRDGKSQKVDASQLVRGDIVMLKGGDKVPADIRIIECSDDLAVDNSCLTGEPEPQKRIPDCTDDNPLETKNLCFFGTFIPQGSGKGVIIRVGDKTVMGRIARLATSTTMAMTPIAREINHFVHIIAIVAVTIGIIFFIIGFIIKTDIITNVVFMIGIIVANVPEGLLATVTVCLSLAANRMAGKSVLVKNLEGVETLGSTSCICSDKTGTLTQNIMTVANTVYNNKIFDAECSITPVGNYDLNNPSFQALQRCATLCNNAVFDEDSKYEKVLAADGTVARGKAKTFKKMVTTSSGAELGMVEWETIGDASESAMIKFCHDKRDIMEYREKNNKLKEVPFNSKNKYQLSLHKQDNDDSKPLLMVMKGAPERILLRCSKLLMDGEEIDLTPERLAEIEDCQLQLSKKGMRVLGFAQKILDPTVYGPNYEFNTDNPNFPLGEKDVDYEMVPKPDPKIEEPLCFIGLMALIDPPRPEVPSAVAKCKTAGIRVIMVTGDHPITAKAIAHKVGILWGPTSEDIEEENKERGLNPGDAGWQDPKTAPAIVVPGWTISLDTPQEEWDRILDHNQVVFARTSPQQKLIIVENCQRRKEIVAVTGDGVNDSPALKKADIGNAMGIMGSAVSKEASDMILLNDNFASIVTGVEEGRIIFDNLKKSICYALAVNIPELVPFLLYATVRLPLPLTTVLMLMICLGTDMIPAISMAYERAENDIMMRSPRNAEVDHLVTKKLVCYAYAVIGIIQATAGMFVYFVVMNDFGYPAKILPELGYLDMFGKHVLWCKTEKGQYCTAGGFYQDSNGDLQPLGRVRSQNGVAECSSNYDPTIPVGGNIFDAYIFYDAGNDGKVQDCQFPFVNVKTTVSKPSTYDRFDPSTYGGYGAKKYLVSYQAMDAADANDFHPYYPMRARRSSFFNMDWFAYGNQDGGLPGFGDKISLDIMYSFQPFGVWGITDDKKLAKDGPPVLGGAKDAFDGTPVTLVDTNGKLTTSTFKLDKGSTFTEASIFEKILDANGQPTCTGEQCLLDYHAGFTLRDGKNLLVNIASRMMQFNALAVAQTAYFVGVVQVQWANVLICKTRYLSLLTQGMHNSVLNFGLMFEFMLCSAVAYAGFVHTIFVTQNMRLTHWFPALPFSLCIVLFDETRKYFMRATSSSVIDKETGRMIRYPGWLEVNTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGD2</accession>
    <name>A0A8K1FGD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGD2"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433808" description="Ankyrin repeat-containing domain" evidence="1">
        <location>
            <begin position="21"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="754" mass="86395" checksum="35D97A39A6E224BB" modified="2022-08-03" version="1">MASVVLNAEWLHALLLPLLAHDDAVRLAVVALDARFDTLWHALMYDRSPIAPIQPRELLPIAIESGWWHIVVLFQRSSRPHHQQQRAHSTLKRSSDKAFALCQWVQRRHPIRFDKEAMYAAVRRGCLEEVQWLSCITEYDGNEALRQAAEACHLHVVKWLLGKHKTGLQRFEVVWEDEGFYWYDDNEGGAMCAMKNHGLLPPHKFSRSYPLMDWAAQRGDLSLLQRLHVDGFVCTSEAFNAAIARGDIEMIQWLHENRKEHVAHIDRVYEVAARENQVTSLEWLHKNSVPLGSLYLVVQVAARGGHLETVRWLFDHCGENINRPNYLLQAALSGNLDLLRLGCHEYGCQVSFRVMEAAAYRRYHEAVRWLANVNEASLKLATENAKALLDASAHGGSLELVKWCVENLGAWSREAAWRAVRGQVSVLEYLHTKAQERATIAKTSLQDQLDFSQINAVHSYLSKIDEETVCWLLEHIPEQDQAVRGGHVEHFMLVCQSPSRKMPSWRFMRKLMECRPMFCCRVPIFPQLVVQFGFLSDLETLKTANHPDLFTKTTLDFILGQSRDDTLMEWFVNECGSTFLTVHFYRIVGWAAKYGATRLLTVLLAMRDKNSALWDKGDFKLYGSIIWPAIRHNQASVLDWIDRQDHASELTQRLWTKRVAKMAAQRGALRCLLWLHTHGKIPDERLNEMAGITACSGQVRCLQSLYRARGIVCSSLDVLKAARKGHIDVVECILTHQPRLFDDLLSHKLEGLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGT2</accession>
    <name>A0A8K1FGT2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGT2"/>
    <dbReference type="OrthoDB" id="166466at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="25245" checksum="4310876BFB86317C" modified="2022-08-03" version="1">MSGRAYARRADGALGGATDIDSVLPHRFRIKAPKINSRAKELAIRRAIQRRVKEKNWKKLLYRQHSRLFPLFPSTEETETTNEATDETTAKDNTVEAKGNGVLTDGEKHTEQATTVTVTSDGQKDVEMESAVSATDLERQQTEEELTLAQQQLQELEAKLQTLSHEKHRKFLQLKDLLIAEARSKSSSTPSTKTPRLEGALGEMSTTGVDVAPEAPSSVQSSTAPTTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGT7</accession>
    <name>A0A8K1FGT7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Raptor N-terminal CASPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="118"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1409"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="786"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="901"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="786"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="905"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="921"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1535" mass="167766" checksum="B2FA8F6CA43E368D" modified="2022-08-03" version="1">MQSAAASMASPYAPPGASGGLHTPLRTSTSGLPGGNAPSGLPGASLGPGFRPSSSSMGAPSFGALSANMTNQSTPLPSRDFLHENYGGLRFARDAAADDDEDTAPDVPEIVPWRMRERMKTMDVALVLCLNIGTDPPDVVKASPCARKECWVDPFSMPAPKALETIGKTLQSQYERWQPRARYRQSLDPTVDEVKQLSVSLRRHAKHDRVLFHYNGHGVPRPTQNGEVWVFNKSYTQYIPLLVYDLQSWLGTPSIYVFDCSAAGVLLSHFNAPPTPGLEDPANPSPSTAGEAIVLAACGAGEILPMNPDLCADVFTSCLTTPITVALRWFISQNSMSMSHLDANFIDRIPGKLTDRKTPLGELNWIFTAITDTIAWNILPRDLFQKLFRQDLLVASLFRNFLLAERIMKSEGCAPCSLPALPPTNHHPLWRSWDLAAEICLNQLYKISHPHPHAEVSIQPSRFFAEQLTAFEVWLQFGASTKPPPQQLPMVLQVLLSQVHRLRALVLLKKFLDLGPWAVNLALSVGIFPYVLKLLQSPASELRQVLVFIWAKILALDSSCQIDLVKDDGHSYFITHLAASMPSSQGSGYGNGPNSHQQAASSMMPPDQKVMAAFILSVICHNCPQGQRSCVQQYLHKICGHLLSDLHDDVRKWMCLCLAKLWENFEDAKRIAIDERLPRLLSARLEDERPEVRAAAAYALGTLVGFQFDGSLYSTSTDPAYVEEFLRQRAHSDIVLSAELLWGCQDASPLVRRESVLAMANVVLHTYHQPRFESVAKHFKNRGMSKRSSLYSPAGASTSTGLPAMSEPTPIVPNEGRPSSFHVSREAHSMEGDERRFPVGVDVQVDSELVDEIGEDAKYYVHIWYILKEMQTRDPFQKVVEAVKSIVSRVNAHILATEQEALRQSASSNDNASAHSAGATQPGSPKTSHTSQSTGSTPALLREGSVPNIPAHAPVGSRRSAPSGEGIVPGNDHQGRDRGEMTNGGTSAPMAPGRSSGLRSAQSVGNFRAQYQEDYRGGAAPGAQYLGQGSVGPGQAVSHLPGMPRQQSARGDPGLMRSYGGMMGESVPTLPNHPPAIPSHGRQSDFPATLCSQFYEKLKARFNLSSLEPASDDDDPLSDKGAEKLERFRRYERIRKAALKIAPGFSLVNPAQPVPGSGKPNIGYGDMAPFNPSYSSPSPSSFTSSSQSAVPRVGIHSDRDEVKSFAMNLRQRAVLNNDAEMTSLLLFHPYETMLIVADEKDQISLYNFEQSEKKVLTFGNKNPSGSRLTSLSWINETEESLLTCGSDDGVIRIYQGLHTPQPVPSSPKLITSFMAVPDLVPGTRGSGLVTTWQQHAGMLYAGGNSSVLRGWNLRQERNTFSVSTHTDSCITTLATDETTGGTIVAGFGDGTLRLFDVRSRPEYALKCTMKEHTSWVVQTHLYPGKNELLSGSVSGELKFWDLRYPKTSVRALEAHRSPMTALAVHDYAPIFASGSHNQFIKVFRSDGEQLALIRYHEGFLGERIGPVSCLAFHPHRLYLAAGATDSVIAIYSSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGT9</accession>
    <name>A0A8K1FGT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGT9"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="920" mass="104761" checksum="9510E133EABA2790" modified="2022-08-03" version="1">MVNPARNKSTCQLRLEARSLAYQQKRQEPPQADDIQRRIQRATETRIGHQRQRKARAHARVLHAKRVAAEIHAQRREALTQSRLAVREKVEVADQRRREQLEKLQEICKRRVEQVLEKVEGVKEVQRYREERQRRLLEDQQLEAARRREEQTQKMVQRLSQRWQCVESVKDRVQRVKFIQRWYRRHVDARKATVKVQAVKAHIERLVASWDKIGKTNFEESMMVMQDRDLARAAQYVMRVLLPSAASGDQSPSPKNASPRSKGASFRVLLMVGMLAAHPNEIMENNQCPRLVFGSKSVLRDMECILVRLEEGEQNPRALKSSVAQLEARFAFYFDMFSLWKDRDAERLAAEMLRGYHDIYRTKVHYAAKDVNLDGDGMHQLIHQTEKQLAQLRSALAQVIGKDEAVARIKAVEASVDESSAPFEMEREAEPSPEKPKTRSSPQKPTTNGVSVPIQRSSQAETAQPPAQVESFLSDEKLVHELILNPDFRIPTQGANSDSLASRIRDNMLKAYWDQAVAANDPKMLLQNLEELRALFTSAVKARADLVGEINDALHPAAMQDLFSNASDHFAEIKGRCGHILQVILRAEAPARAESTHDFVAAFDSAFRELVSQESSDVSRPVRILVDFLAFALKKVEEIRTDMLNVHLGMLSTYLSRHGTAYEQKKFNEKVSSGVQLPMTSQWIATELERQWAKMSSEERSRLVQGDTSAVRMSLRSSMMALIVSYVDGKAGVWPELFVMDAERIRSYRDSMDRMTVVCSLLVVVQDYLARRRFVVPRDFFGLLAKDLGDLLRSAGVSGSHLIARVMNEIKQSQTSHGINVEDDPEFVALEQRLQSTFQSGSPVFGLFFSRVVGAVESVALHERSQWEMHASLAPFENELRALAISVQKLFKHNEVVHASFYNAAIKNAIANFQQASQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHM6</accession>
    <name>A0A8K1FHM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHM6"/>
    <dbReference type="OrthoDB" id="156249at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="38267" checksum="0BE63FED16ED2E81" modified="2022-08-03" version="1">MVQDLEQQREELVEKLEQKELSKEKEASVWQTIADIQRQQRLQTEQENRQLKEALEQQLQMAKRLEEGVRKKRASEVVLTRPFDQKRSRLDHTMALLYSQHMRDIHRGYNQLDEIFEWANGIEHLESPVIGSRLDEHGLHQPYVELRERRWVPYEFSRVCGALWQATVSEYLRTREGVEAHCEPDSLVIRYDNINHKPERDGLLVGTVVMKKFMEPNRMILVWRGTTTAVEEQVDVWRRPFSDETGWVLVERDPESDTPATRSRTCSRHYAQWDPESGESTKRTPTRLRAEDFEKLVLGSTLDDMACIVEAFENILLDEDALSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHZ9</accession>
    <name>A0A8K1FHZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHZ9"/>
    <dbReference type="OrthoDB" id="168132at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="805" mass="91183" checksum="C25FF542CCC66CAB" modified="2022-08-03" version="1">MTVTVPTWFPVLSPSDVAIDQSFEGLIHHSRFSNTQRALLQGTPVVALSFTSTTFKTQLWQSTVDIITEQLCQASTHPTFVQTLGVVGTVEADATNTSLYHLSPSYVVMEAMPVSLYDILHVEQLPLTREHIILIATEILRGLQFLHHRNQSFCSTLTSRKVMLGSTRHIKLRRFGLEQIGQKAETPDLVAASYASLSHYIDQNGHGHDESADILDLKAADQAVTKEVRDKQCEDIYAFGVLLLEMTTHEKPNVEIFNRISSTAQVDPVLETVIRLALGVTPSGSRSGVTYPRELLNKCLESLSSIKLQHRVVAVEGGKPPHSVISFPSFVQADDYVQRHESAVVLKSVGDRDRQNEVALKRLAAVEEDLVEEQKNFEIVVRQLEQAKIVLGHRDDELEQETQRTRALHEEIAAHDEMISNLQNDRNTALRTIEELQDTITSYEERLEQSRIARLAIERERQELLVEIMKLKDEKRAVLDQKAEVESQYAAVAAKVGSEKEAIEELEGRYTQAIHRWKHEQAARAQVERRLEAISQQLVAMEDERARFSAALQSTPLGGRDPRESSDYVLDLKEKCIASLQNDIQQMQKAMEELQSDLERSQSENHRLQQVVITDLEQQTEKLMDELRNLEQHFVEEQETTTELTKQLEEITLEHDLLKQKAFALDLEVAEMKKKADDEEQARRQRRCLTPNCDAPKYLVRPSGYCVECIEKMAKGTPSGSTRKTPAVTAAAHLTGQKTFLDAPRNMQTVEILRSIEKAREDLSPEDDDPRNESMTELVCLLKQFSTLLKENGSTLPLFSHIFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIM1</accession>
    <name>A0A8K1FIM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIM1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="394" mass="44178" checksum="95BBBE49C6B5AB70" modified="2022-08-03" version="1">MEDEDSALLTALLDTLEADDALQSILPHSETDVLPQKRVVSSKRARDKSSSTRQKEEITSLRAEVDDLERLRKRLRQAHGRRLAVSVAQQELASMWKAIADRQRGLRAKAEKENARLHAQIDNQFRDGRDVTAVLCADLSDSFVTLSFKGNTKVAGTRARQEHLYKQTHVAFTDPCFSDGSKTFRDFKIIDDDGMATIIGGREGWTSPFTANELDRALWATLRRDSTWRDGDYVTELEVTDDSVVVTLESIAATQGDVILGKFQSKIVIRRFQESPDAPSVYISCFYAEPMPSDGSAEQLTAYEIMWYRIREISTGEDVTLAPISQLQASRRLCIDCSGSPPSSRKETLEIVTEFALEALRRDAESIQELVEHELVRSSASSPPVYSSELQLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ32</accession>
    <name>A0A8K1FJ32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YrhK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ32"/>
    <dbReference type="OrthoDB" id="369339at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025424">
        <property type="entry name" value="YrhK_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14145">
        <property type="entry name" value="YrhK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="YrhK" evidence="2">
        <location>
            <begin position="33"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="YrhK" evidence="2">
        <location>
            <begin position="113"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="YrhK" evidence="2">
        <location>
            <begin position="189"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="28418" checksum="5A91DA7C3679E760" modified="2022-08-03" version="1">MPGSQYSPEYNNHASPAILGTKVVHGITFAEKVFQITKVLAYFCGSVLFLFGSVLFLPKYATLWDGQGAVVGSWVFFFGCICFMIGTNADFIDLIRYSNGTTTRRIVDAYIGLLYVAAGGIFQLGALYFLPDYYVTAPSLGCWSFLIGSIMFCMASLWDVVNITITHDDPKKSGVQLSNLYCWGTLVAIGCFAGAMCFIIGSWFYLPKFIAVEDADYALHYMNKAITSYIVGSVFFVINALAQIPGLQAKLSQKASLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK28</accession>
    <name>A0A8K1FK28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK28"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38137" checksum="9797A09EF6652229" modified="2022-08-03" version="1">MLPHANAAAFASPIPVTSVCAPCMPDCLASNTFEVRSMLRWRPTQLTFVSMFDDEVELYYGPSSDRTTMVRIKRSATEPNAIRLKEKPTKCEFSLTIPKRLTKLRLRAASPREYALWVHVIRAALGGPSITVQSIRALEAKATPGYASVFMHHLARVPTQASSVATAAESSPSPSPSPPSTSSTSSTSSVRTPVGPIDPIDPVDPVDPVDPVEGLDLASLVSPLRSPLSWSVTPLTPSSSSSSSPRSSLLSSRSRSSSVSSLLSSLLTTSPIASSRGSFEFPELHVELDVELDVEVDVELDVEVDSPTSSAGSCDWDQELEYALATYQTTIENARYYEPLHHKTSRVSLYTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE2</accession>
    <name>A0A8K1FKE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE2"/>
    <dbReference type="OrthoDB" id="10251131at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15589" checksum="2D51F59DF9CCF861" modified="2022-08-03" version="1">MADKVPVTVRTRKFLRNALLARRQMLVEVIHPGRPNVPKAELQEKIAKMYKVKDTTTVFLYGFRTAFGGGKSSGFCLIYDSVNDAKRFEPKYRLVRQGLADKVETSRKQIKEGKNRGKKTRGVGRRIARHKAAKANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL55</accession>
    <name>A0A8K1FL55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL55"/>
    <dbReference type="OrthoDB" id="271164at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="439" mass="48962" checksum="1FC9D4C0E5635137" modified="2022-08-03" version="1">MSIAVGPAGKVGDGVNAYYVYKVTSDTFSIEPIQVDRRYSDFLWLHTQLAKQCAGYIIPPLPAKVVPLLQGSEFLERRRSGLERFLRKVVEHDELKNTNYFRSFLECSPVELTALKAASQKAETSTSGNGSPGSSSSGALAHMAQKSQQLNSWWGKAYQRMAENDKVKLLAAKAGRDLTGVNTIEDPDFDRVLKYVSELNALVKSMQTRAQNAHKANKLAAGAYCELIECMNTIADVEESLSTSSSTASSDFGAVLALLDTRARLMDSELAEFSESIEYFARWVSAVMNAINVREDRRLTYQAKLAAKGKDANNNASQDVLEAKDEYERVHQRVMTEIQRFQAEKAIEIRRMFAQYAKVQMLCTTEMSEVLTVSNKALEQPVTTQQFTTRFSKTGEPGNNEANEMEEAMRKMDIRKPETTTAVNKVDPEGNEQYSDVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM36</accession>
    <name>A0A8K1FM36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="11">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_013079</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 11">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Glycosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM36"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020015">
        <property type="term" value="C:glycosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(P)+]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000019">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(P)+]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000940">
        <property type="entry name" value="PRK00094.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000942">
        <property type="entry name" value="PRK00094.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF1">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0327">Glycosome</keyword>
    <keyword evidence="3 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="2 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="12">
        <location>
            <begin position="28"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="13">
        <location>
            <begin position="204"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="279"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00084116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="354" mass="37824" checksum="6B7892001D6988A7" modified="2022-08-03" version="1">MEAFLGSSGVTSGATNAGLPSADVERVKVAVIAAGSFGMAMATIAARRGHDVVIYARDEVVVDSINQTHRNPKMFPNHELLPEISATTSVENATADAKIIMMCLPAQRTPDFLAQYKDVIPKDAILVITSKGLYLKTKELLSVPILAALERDQPLSFLSGPSFALELMNKTPSAVVVASKYLYHAVYVQRALSTVDFRVYSSQDIIGTQLGGSLKNPLAIGAGMIEGAGLGINTLAAYVTRSSLELQKLCVAMGGQPITISGLAGIGDLMLTAFGSLSRNRTCGMRIIQGEKIEDILKETTVEGVPTAEVAVHFADQCGLDLPIFKAVNAMLKGQIKREEMQNLLMNRPLKSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMH5</accession>
    <name>A0A8K1FMH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMH5"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="60"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="431" mass="47833" checksum="C631FD061A8B71A4" modified="2022-08-03" version="1">MVFGSCLSRCIVNDMATELEIELDESGRNLPAKHELHSTPANGTTSTTFGTTSLLAADEVMCLNMIGEGPSGVIYKGSYRGSPVAVKQMKMISMPTHPSAREAIESALEIEASRMGSLRHPNTVLFMGACLQGDYFCIVSEYCSHGSLYNVLHNPNVDTSPSRNKRAASKDSMPPRVNGTSGNTMHSFHTTDSKKKKSTLKWSLRIRLALGAARGLLYLHSAEPPLVHGQLKSTNILVDDSWNAKLADFGTRRVAEAVGFDRRRLEKVDSDTGLLRWTAPELLKLGEERVFKGKLPSGHVSPQAVDVYSFGIVLWELTTGELPFADCKSNHEIRDRLLQGLRPPMTPGNYNIKWADLIVRCWSDDPLRRPTAAEIVSTLEIINKEESLVQAEKRKARVVNSNRADYRFADRKHSKARNASKFRTNVRVPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMM0</accession>
    <name>A0A8K1FMM0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002734</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMM0"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000023">
        <property type="entry name" value="Transmembrane prolyl 4-hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="8">
        <location>
            <begin position="256"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="714" mass="80640" checksum="7A1B6FE63B4D99B9" modified="2022-08-03" version="1">MAKKQAQPTADIKAAAAPKETEAEPTPPQSPNKASNRASKSSSSVALPAIVSLLVVFAAVLVSPSDKLDQIVPGLGRVPQKLTTTWNSLSNRALTAMGKTPDKYKTDLVDVEPRVLLSNTQCDDESYMPTPLLGGRILPVTDAMDVPKVGSDKVFFMLNGRNEGVYMSWNGRFECLAGAAEAAAKWLGADTDEIDNGVRLYTPMGKAIRDAAELSGAKNMAHILLDFQLWQWPGIKLGYKYVLEDGVELTTVGLTPKVFDVKYFFSESEAQAIMDHGMPALNRSKVDGANESVVSKSRTSHTAFLKDIEFTRDFRRRSAHVARLPSPSFAERLQLVRYGAGEFYRQHLDTFHSREFLPKGANLFTMEDYKTWTEWAAAKLREMDQGKLPEEFREGGKLFPNADDDTEFPNAFMDLFYHDAKAKNTFMALSDEEWATWIRTNVDKNASGVMTSIMKDTNKPHYLPLAVRVWEDKLGLPELHYTFPKKPVNGVSHYFRWVRWAKERVTYLGDQAPAIARPTGELYPKFTVAFQRVLVNIILDDYSEDFVTRVLNKEWYDWVKTNRKSNHVLFQAMQSFPHFAELAIRAWEKRVGSPLFQYKLPKFVRHFHPQRYVTLFLYLNNQTKVGGETVFPFSTERFSEEKIERTGMNECSTGLAVPPRGLHASLFYVQTPEGEVDKMSKHGGCPPHEGVKWGSNSFMWDSDADEGADLWTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMT0</accession>
    <name>A0A8K1FMT0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="431454at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="163"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="486"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1225"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1304"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1326"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1365" mass="147978" checksum="28504834A74E975E" modified="2022-08-03" version="1">MTEDGDGESASMEALWAFVQRVAASPDGEESVDERLARFDGLQQEAQRLLTARSRTLEHEDTHVASNTAAATASTAAGDVTSTDAKQQELYEKANERVARRMLERTESHGDDSEDKSDTMSDCTTITEASSVYGIQNTWVDLALLYSLPFVASESSGSASNGSRHHRLKPVPALNIAQEQNSLNKIFQECQRAIHTMRAAATVDSLRKVLDRGVTVLHFSGHGGRIAGKTDCLLFEDTQRTGLAHFIDAATLRSILNGGVASGSASPPPSSAFTGLAREDSAEDDGASADGHSSTRSIASSYSRIGLGGTLKLVFVSSCHSKEVGEVFIQAGVQHVVCVRSGDKILDDASAMFSYAFYHAVLAGKTIYQAFEIARVRVSADMQIPDHEGDKFILLESSQVHADSCPLYDSSSDDTPYAIEVNFASNPCTCHASTMHFVFSDISAGKWVDVSPANRFSKTLPAIPESFVGREQELHMLAGLVNSQRFVTMRGPPGIGKSTLSIRLAHFLAERNVFPDGVAFIRLRGVQSLEGVETAIKSALFPDGGREKELPLQQTLAEMKVLLVMDNMEDPINANPLPVREFLLHLLQNTPNLAFLMTARQAMGGGIAGFDEKVVSLNRLSHFHAADLFLKKSPRALLLSEIGDIDAKASTHSRTASVLEALTSHPLMAFLDGHPQAISLCAPLLQDRSLSELTRAVLSRGVSELQVVGLAANDRSAMNTLVTSLDVSLEQVRLHHGSDAIRFFALLGLLPAGAMPADFKSLWGNKWEVVVETLLRFSLIQRNRIPGFVLSSTSRGLPSQTSRRSSSRLSSSRHSSSRHSSTQTYDVALLTALKSYGDFISSASATGSAKGADGDHSALTSSSSSRSGFSSERNLLNTFTRSGRAARVAEHVEKMDNQAEVMAVCVSYSTFPFITSYARSLLGLYDGDGAKNAALESICVADRDRFLYNTARHFWKVSSWIFQYICTLTARSSAAYLILDMHESNLWMLLDLHIRMMEEWRQDSEASDGGDGFAAAECSPEVLALREKTSSYVVDVACFFAHTLFLSGRHRGAWNAVNKALHIAKAHKDTLSEANTRKLMGILLTTEAKFDEAKAQFGMSLILYKAVGDKMGQAASLSAIGMIHSRKGNLRGAHNCFTKALTLYEWFKHALGQLNCHQRLANLEKKLRDGDGLRGKNGQSSGHSHHYAATRRLQGDLNRKRNGEYIVRWVGHEMSLLLELPPSKPDKIQEAHAPSNVVTSTASAPMASDEDTSDSAAACSSPKATLSRPTSSPGVTNTPKKCRLGQIIDQREQKAANTVGEPNSVSTSTSATTQPPTNETTSTDAVAERLKKSSFARRKEYDASIRRTLSASMVDSSSSAAEDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNB9</accession>
    <name>A0A8K1FNB9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNB9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="272" mass="29714" checksum="290B1778AB590D55" modified="2022-08-03" version="1">MVEDQLAVGEAFAQPLSLSSTEFLIKTVHGANEATLLKAAEPIRDACAKELTVYCPDQFRTAVLTTRHYLEGDGVSLWTVADACRQVGFCLAKNADVLSTFCKYTIIKSLTMPLDSWTPMPTPSGTPFSPPPFTPPPGTWGQAPSSRPGEHKKWHHGGRHHRIRLLDEDSEDSNDHKTKAGVEVYVINNGGGPGGQGGHGGFIGRHHRHPHHHHGPGWAHCVVWAFVLPFFCIGVYVTVKHAITYIKKRQASLPVAVRSGGYEPLRTTESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNL0</accession>
    <name>A0A8K1FNL0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNL0"/>
    <dbReference type="OrthoDB" id="175806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="122" mass="13249" checksum="7A31AD7941BB1F63" modified="2022-08-03" version="1">MKTYDATGATPHTSREDPKAPLISMHTQPTVTSVAPASIVQVYVCDYYGIASPVEVPAGTTLYGLVCAAYEKPVFTKAAFLGFEDGNLSMVQSVTAADATRWMADKPLRLKYKRDEDDPCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP39</accession>
    <name>A0A8K1FP39_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP39"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18311" checksum="AA521E116A0879E6" modified="2022-08-03" version="1">MDYGEDDYASYEPDPPGTHDHAMLSRQSFKLLKKALASKLTSAKNAVLTRKQSLPNFRASLSAMTSIKNVLPSRTSSAQTYETRSHRSASAPETASGSWYHYEKTPFYNQSRFTTSTSHYPDFWNDNQAEDIYHSTRFSEQSHEGDAYYTYAEASDNQTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPB3</accession>
    <name>A0A8K1FPB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPB3"/>
    <dbReference type="OrthoDB" id="163346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="65530" checksum="ABAE2283BF3A0289" modified="2022-08-03" version="1">MHHGQCDHVAPPRQNIVLLEDPDLFAYNEPEPTQFARNTSRYTSATTSSHPSQPSSQYYQNLTPDPSKPPAPPSSVGTGASGYGAFRAGGPVNLFSRTYISFLINWLLIGFFNGAMPALTYPLFQVYLHLQAYQGNAVLALIDFAWNFKFIFSFLTDCVPMNRYRRKPYLYIGWFVLTACLMGFTFRPQVEPYMRDGVVVNNDAEWQGPRHVIPLIVMSFARILVIVASEGMMVEFAHREGAMDRGETQAIIMMARGVGQVLGILLVAFGANSEEFGGTFNSSLSLRAMFGIWIAFAFLGLVTTRFIPEDQVPSSSQPFTSQLHRVWRMVQQRVVWQVMVLGFFLNAVLTLNYGEKNTLYQMRLTEHTLGLNILDAIKVVGSVIAAFVIYRFMLNANWRKIVVWSLVAVTVVGTPIDSITIFDALPSVALFYIKDFLVSIPTALIVFMREFVIVEITSPGYEAVTFGFITTVHYLGKPLAMMVTNLFAMDRQEVQNDTSEVRWHLAVELWIVIAVRLVVILAVMKLLPRDKRHALERKLLGNPNMVVPILIFLCVVAVFCAVVSSSFLAVIKNTSCLKFAGGSGCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPD4</accession>
    <name>A0A8K1FPD4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein 65</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPD4"/>
    <dbReference type="OrthoDB" id="430821at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019537">
        <property type="entry name" value="TMEM65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10507">
        <property type="entry name" value="TMEM65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="25126" checksum="C9B1CC7C8FAA53D9" modified="2022-08-03" version="1">MAFLARSWCVMSPKVVHRSLLASTVRSQGIRFVHSRGGASSETLSVLHDLQAALKDPHAAEKLGGMLSSSTTKNLTRALASVKHEQHIAGATAAAAAQAPEAPKATISMQELKYVALQVGLPFIGFGFVDNAIMIIAGDYIDMTVGVSLGISSMAAAGIGNTISDIAGLGLGGVVEDFCARLGLPTPALTPQQMMLKETRIAKVVGSSIGVTIGCLLGMLPLLFLETRDDKKQEETKVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPT2</accession>
    <name>A0A8K1FPT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006152</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPT2"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438618" description="G-protein coupled receptors family 2 profile 2 domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="47"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="37867" checksum="8ECD6BD062CBC300" modified="2022-08-03" version="1">MLAVLCVMLASWIPEVVGVTHKVVSSQALDAADQRLLSSTSSEISVARALVTASSVCSLCCALSIILYFVLNQDSRRCGRRILFCLHVADVGVSSAWLLSWWVSPTPSTDAPEAEASPLCMAQGYLLVYFSLASYLWTACFAFHLYQILARRSKYPELYESRYHVISWGLPALTVCQLVVQEISGATLLGESGRPWCWFRTWSDYEWVRSGFHAQLALFYIPVAIVLVHNLATYISLLYHLSDILSTKMEERIWRRLLAYSWVFFLSFVWGIFAVFYQATSPNHELSPSMLYFMSFFTPLQGAMNAIAYGVNEKMRRRIKSGLWQTRQPTQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQQ8</accession>
    <name>A0A8K1FQQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor Tu, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007879</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQQ8"/>
    <dbReference type="OrthoDB" id="1727108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000084">
        <property type="entry name" value="GTP-binding elongation factor Tu family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="67"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="58880" checksum="C1C7FAE0DDBA7A7E" modified="2022-08-03" version="1">METTSNQQEEELSVQEHLAILTLKQQALQGETNQGDDGAPDEALADVQSALEAAEHDETLVLDKDRVRTLRVAFVGNVDSGKSSLIGTLIKGDLDDGRGSSRKAIFRHQHEIETGRTSSVATAYMGFDEHGEQILSKRAGKTIAWLDLAKVAYKRLQLIDLAGHEKYLKTTVFGLTGMQPDIVVVVVGANMGVKRMTKEHLAIAVALEIPLVVVLTKIDIAPKNIAKETLQTIRQSLKRYGKMPMLVKSEEQAIAAAKGIPSNRITPILPLSNVTGDGLENLRRIFFDASPTALFKASLAATTLAGLKSNQKEAMEAEASTQSATSTDLVEMPIDETFQVPGVGFILAGTLVTGTFKVNDTLLLGPDYNGVFHKVVIRSMESMYVPMKEIFPGQTAAVSIRSINKKHVLNRQTFRKGMILLSLNVNVADYVSQVFEARVVILHHQTTVAVGYQPMINCRTIRQTAEIVWIDSSQDVIRTGDRALVRFRFIHAPEFLKKGMRFIFRDGQAKGIGKVVRIVPPEEQNNTKNRWEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRN9</accession>
    <name>A0A8K1FRN9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRN9"/>
    <dbReference type="OrthoDB" id="151325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="39078" checksum="DA1C3BDCFE9BE329" modified="2022-08-03" version="1">MYSIVCGQDVVFSVEVDADMVVWHLTTRIDSMLEERGFDPYQYELYIAKWKDRWLTTSEIHDFDSIHELRLLKGRLIALAGLGLSREDVQQEEVDATTPAQAPVHVLLSKPNPKPWRWTDDSPPTACFTASVREAYKCDEPRRIVRCMVLDAALPANFVVALHLYKPLEPRFAPDFEDIDDMRNGLVVCKRLAQAYVALQICFLYDAQSDQFRLKVLDQTLANERIVSRLAEQERVELHDGREVPNMKKRGKAQWFLPHTKFDIRTTFGDLDARSLCFRSLLRPFKRCLYLQARLARWRAIESHWHGAKEVRIDDFRDEGMSLAPKMEFFNARSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRZ6</accession>
    <name>A0A8K1FRZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mucin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRZ6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482935" description="Mucin-like protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="21787" checksum="DC78E5F01457DF57" modified="2022-08-03" version="1">MRVAGRRSRALWLVVLVVLAIALLGVDARTRVVDTTADEESGAISADAAVDAAKSSVPPRTADEEVEEAEANLTPTVVPSKQTPSPTPTKATKTPTKTTAAPLPSDDDTLVSSDDSSADSSSSSASSNDSESTPEPETTETRGPDMTMPKLPDISAEKLTGDDGTVLRGSSSGGLDKTIVLIIVGGVACIGALVLVVSRRISKESRTADDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C260</accession>
    <name>A0A8K1C260_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AGC protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C260"/>
    <dbReference type="OrthoDB" id="58979at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="150"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="416"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53768" checksum="B1FBD0E280969441" modified="2022-08-03" version="1">MAPVTTDANADDPAAVPTTLLDGLMMEYQRTDVLVECADSENASRRRWGSVKTWVFGHLLASSFARVSLNGRDSLESNCSQLEKAITDSAVTVSASSSTSSSFVGPSSPTASGTVTGCNDWDVCYKSLNMPSQSCNQKTVVTPGTTRCEFDILRIIGSGSYGTVVLSCLREKPSRLFAIKMVPKCKVGRDRTDRETCRLLTEKNVLAAVDHPFITKLYCTFETEQSLNFVMEYCAGGDMYFLLEKFAKNRLPERLVVFYAASIALALNYLHQRGILYRDLKPENILVDRQGFVRLADFGFARENMGLNEQTCKTFCGSADYIAPEVISGAGYGAAADLWSFGCVMYELLMGLPPFYCPNDRAMLFRKIERSHPSFPSHVSPEASDLITKLLHKDANQRLGNGPNGMRDVFSHPFFASVDWYQLSTKQVVPPFVPQLIGAMDTSYFEDQYTQQHVDGSVRFEGRPAEKNLFEDFDWCTNDEAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2F3</accession>
    <name>A0A8K1C2F3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2F3"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="163"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="521" mass="57900" checksum="E9B425D7F0B02449" modified="2022-08-03" version="1">MTPSLTQLLQDLEFQYDARSARTLWVPRVRSVRLEASRTHCTVVETSADASRPEKHRLELLWQDVLGAHILTEDGEHLALPIGLESVSKSKTYVFVLFAFPAKNHSPGSLKRRVLRQWLFRFQGDKMTDMVELLTWLNYLADPRSQEAIALAPSLEELKPVTHPTRKYLVIINPVGGAGKGVQMFEKHVAPIFKYTHVEAQVQLTERANHGTDIAEQLPLGQYDGVITVGGDGSLCEIFQGLMKRPDWKDAIKVPIGVIPGGSGNGLFASVMHGLGERFKPANAAFVIAKGLPQPLDLASVRNPHGDQMYSFLSTEWALIGDADIESEKLRMLGGLRFTVMIAHHVLLLRRMYGGRIWYLEDDPNNTSAVVPHNADEGSERPGFDLFENLEEGALASDGSGARWRKIEGPFQLSWAMNTSHAAPDCHTAPGAGLNDGYTYLVVLHQKHSRKDLIDLMLAIDKGTHTKVEAMDFIRTRAYRMEPENPDDVFCVDGELFKGPVESQVHHNVARIVSLPPTQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2P3</accession>
    <name>A0A8K1C2P3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2P3"/>
    <dbReference type="OrthoDB" id="122451at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49012" checksum="62DFAD73F1C68F45" modified="2022-08-03" version="1">MTNDAIMHDESSTESEFFDSGDENTFKTSSSAREKEFYQSNATFAASVAHVEPKKDPTEGTARAQQEATEENTQPVLESEQPRQVVTLSADNHSLSLPSLTMFGTTTTMESSFPSDSTNSTQPAPRAPPLSVVAVPLRAPPMVEAPPSTQVPQPVEPPSISCIKCRRSLSTDSYPIAAPGHGSCVCCGRFYLESKLMTHEDNQYCGECLPSSDACRRCGRAFISLPSVAPDAAIKCSCCEQLLPRNAFSNTQRRKPDENRRCKVCIGTLSQSIMDRTARSDWVPKTLRSTWNTGPSEMEVKITKIKLERRALQRKHDANDLVGATRLEYQAELAKQESKLDQQAATLRRSDPALYDELNATIKIKTANAVPRSERDSMQDKKGLKKMQKREEEREKKKTEKKKRKREEFHAKRRAAKAAKAATNAVSTVSDGTTEAEGDSATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3R4</accession>
    <name>A0A8K1C3R4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3R4"/>
    <dbReference type="OrthoDB" id="77038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="27536" checksum="E444DBB9E99F746A" modified="2022-08-03" version="1">MMITKPLVCPESPVDTSMFPPIYGTPMKETKVNTFSISADFPTNKPVPKSECVVYDSEIEPFEYKPSVTGIPEDSLSSVFGDADLINSIMTSLETEASTAPAVSPVLLPPTPVISSYPCLRKPGTFLNKDGRWIKGKPCRISNCDKRAQSNGLCKGHGGGARCNVEGCSKSSQGGGLCRAHGGGKRCLHEGCEKGTQRNGFCYLHGGVRSCNVEGCDRKDRGNGKCFAHGGGRRCQAAYCSTTIRKGSFCAKHDSGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W2</accession>
    <name>A0A8K1C3W2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3W2"/>
    <dbReference type="OrthoDB" id="163070at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="46062" checksum="78DDC22768725CFF" modified="2022-08-03" version="1">MLERHDVDILAMLLAEEDAEFAQETESRSEAKVKVRDLNSSRQRQREELQYLRRRVTELESELAAQKQMHRSSDGTLRVDPDASPTTVGGDGALTTGVSEWEAIALRQKKTRQRAELENHKLRQMVESQVRVAKTLEKLLLKRPNALHVDPSELKRRRRFYQMTSDRDEDAGIFENILASIDRSYAETSVVLEGNGLMRAPVGHRSVDIKAMQGNTSGMTDVYVELTDVSTMPFSQEATASAMWRCITSGYMQLHHEIYKAYAGSEDILAIKYTITLTRRRLAVDFVARAAMKRFVEGDRVVDVWECLSDTEETRSGSNAPGIQVRERGWTVLHPINGGASTKILSCMQMHPLVIENNADEERRVGVLTNLALDYYGEQIDQAHHAIESLLLDETRSTVAISSLVDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3X5</accession>
    <name>A0A8K1C3X5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008603</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3X5"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000006">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000006">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF3">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="57469" checksum="4EAD22A7A761CD57" modified="2022-08-03" version="1">MQVRNQKPFRRNLEPDMEPNNNDKNAVASLYQQTEAEPLYGHPLMCASLPTESFPQRSVPARVAHQLIKDELALDGNPKMNLASFVTTYMEPEADDLMVEGLRKNYIDLDQYPQTAEIHNRCVQMLANLYHAPLQPGEQATGTGCIGSSEAIMLAGLAMKRKWKDRRIAAGLPYDKPNMVFGSNVQVCWHKMCKYFEVEIREADVSPDCLVLTADRARPLLDENTIGICAILGSTFNGEYEDVKEIHDMVAEVNEKHDWHIPIHVDAASGGFIAPFINPELEWDFRLPNVKSINVSGHKFGLVYAGIGWAVWREKEDLPEDLVFHVNYLGGDQQSFTLNFSKGAGNVVAQYYNILRFGFEGYKRIMEASMENAEYLRSSLVATGHFRIVDKQHMPLVAFALIDSSRYTCFDIQDKLKSRGWIVPAYTCSRGAESLTIMRVVVKQNFSYNMANMLVHDILKAIDALEKHHVLVDTAMSSPKAKKMQFVDVVHAIQANLEHQKSGLTTHGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C410</accession>
    <name>A0A8K1C410_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TatD related DNase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C410"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47176:SF1">
        <property type="entry name" value="OS04G0577500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47176">
        <property type="entry name" value="OSJNBA0020J04.13 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32604" checksum="8A29AAFC58C4DFF6" modified="2022-08-03" version="1">MATHRSWPRVFDAHCHLHDPRLSAQRSDVLQRATAFNVTYVATCACFEEDWTALDELLAEMKAAQGAGQPFVDIVPAFGIHPWWANAQSDQYLDKLRAKLDQYPRAALGEIGLCKSNRGRQVDRAVQERVFREQLELAAELGRPCVLHCVGVYGKLLEILQSVQKARGLPPAVVLHSYSGAPDMIPAFLALQQASRGASKLYFSLNAKQLSSQPKAIQACTKVPLDALLLETDAPDQALDVAQVSAVLGEETIVVDGLNEPAMVQLALIKAAEAREMSTDELASAVFDNTVRAFRVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C491</accession>
    <name>A0A8K1C491_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C491"/>
    <dbReference type="OrthoDB" id="8026949at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="331" mass="38410" checksum="F9ADCB78FE78A132" modified="2022-08-03" version="1">MKGMALRRVLTRVASARAPVAAVQAVGGSKSALRVLVATETRTFSSRGRGDDEEELNGKINGELSPLERLLQHSQQFRDEVGLDELPSDVADEILGEHDEGEHREVDEEEEASFDEEDHEASWEHVEDELDAREEDHAEFVAELRKPRGPRAQRKQRFTRSRDLRATGGLEASVRRRLLRESEIDYEHGLSHLDERRAKEHIYTQLLERDYDHDRICHNCGERGHVARNCLLPTICSNCGDIGHRRHECPHHVYTPDELARIERQRKAKKVTPETAELDPEVRRHLELRSIKSRHERMKQAFDDELDEYLNHQENLQKKRKQRRGSQSEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C499</accession>
    <name>A0A8K1C499_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C499"/>
    <dbReference type="OrthoDB" id="68584at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478354" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19265" checksum="47EAA917108444B2" modified="2022-08-03" version="1">MKTPVLLAIALLCASVNARNCMSTCRTQLLNAYEKDCSAWREELPRPDLYNHCQMGYVQGREAACEVYCDPHGAPDERKLDTLRMDACLELRGRPPSDRINACYEGFVAARARAQGVVTPSLKAEVDDTPKETEPAPTRRTVSVKRQAEAKNILEMAREEAHAAFHEAKSSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C556</accession>
    <name>A0A8K1C556_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tubulin--tyrosine ligase-like protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-[protein] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60144"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143622"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60145"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C556"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF145">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476710" description="Tubulin--tyrosine ligase-like protein 5" evidence="7">
        <location>
            <begin position="20"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="681" mass="77819" checksum="C25C15F3331CC297" modified="2022-08-03" version="1">MLLLRVSTVVCAWVVGVTTAVPSGRSDARFYLTEEPRQEHKLLLEQLETLGIDRFIAPRTQDDPEKEDGWSPVSSQSDQFDLVWSLDAKSPFDQLSFSHTFRAKVNHLPGAERLTNTDIFHRHIVDNQRRKEKFFFNFVPKHFMLPRDEAKLPNEFEATRKKVQFELKRERDPLVYQRYLVRPVPKSGNDDALTPAVVVSSEKELQEKLQYEFKGQEVEFTQYLEPFLLDGHKFSAGFYVAVTSLDPVRVYVFDHALIKISKTAYPANLDVNSDRSTYNLNEYIPPWDFPDLQKYFYEFPSDTRPGTNAWKVVKRYLNMQGIDTKRLQREINDAIVKSVISSRGFLQSQVGNLKRFKKQDEKESERTDLSESFFELWRFDFELDDMGKPWLSKIHSNPSMTAEKSVFGTDEAIKKRVIFDLLNLVGVHPQASPSFDKFFRPQDAAFCADKCSDHSRVWDTACWSCPGWFAPYIARRLFDSMNEYARRGGFNLVYPSLDQDYSKFMDNALSELDIAFDRYIRSLSTAYGEKQTAAISDNVVVCVHREHCNDNGDCVNAKCKCDDNYEGSTCYIPKDKALDKRTKAERAGVAPVGESWKERVGNFWNRYGTPAPAQGALGGEDGAQTGATGQTAKLVSKPLSEIDRFSASKLLFGLACVTAFLVVAYRCLATNVETTDVHKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5B7</accession>
    <name>A0A8K1C5B7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5B7"/>
    <dbReference type="OrthoDB" id="160518at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067:SF3">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="821"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="822"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="881" mass="98292" checksum="A3DA7ABB4E2DF44C" modified="2022-08-03" version="1">MTVTRESDAATSTSTPAATPRQRKAKDRGAKFNEKHALKYGLSICSRNAKDNSVEMVMCKFCVAFGKESLSDATRKRRATANIKYFRQPFRADHYVSHLEINHKVKWAEYERAEGAEKEKFFSFHLEEGVAPPPPPSIASMPLTTAPMDDAAMEAVRAEVADNAGVAGVPGSSTPMDPLTLQRFVGPVRIPVSEIEKELVERVIGDLFFDAKEERGVTMTQALSMFTTKENTRNFEITIKNQRLYDLAIRFVSCGASYRLASKLIQCTKEETHIGFYGGCSDQRVANYIRAVMASNLQRVAWMMRGSWTYAIATEAAEHQGTSYLDVRIRVWHNGGLRDFHLMTLPAFDRHPATTIMQRLERLLTVLDPRWRSKLLGTTANGGANTGRNLGVTGSQQGLAARLTGLVTRPGFYLIWSGIQQLELVAKNCVVAFCDRAFFDDLLVTVNIIRKEKHGSFRADDLPDLASTLPTARGFVRALLKVLKRLMENHATVTQVMTHFGGATQLSPSWWVCVAVAYRLIAEVDYFMKKLLSMQSGPQLVNDQVQELCKLALIMADVVGARRDLWDARDVTDACTAGSFLLTFLNAQQFIQNEGGQLAIEMFDSLRGVDRTLISKAVAHFAVDLVASVAAITQDGRHYCADSSGIVVNPPAVLPYAVYKMGKDEFLKLLQSQEHRLHETYTAEEIRRIQGDYYYFQVAVETETILSNVLKKHTRETDVSFAWSCLNNRFMMLQEFIGGLSCVVPDASAGSLSSDLLNLNWEKPDYRDSLVDFALDGILHARQKMKIEVVDVNYLRALLRPADHERAQFEAARSRLMVPIDTATPAGGPAASPPTAEVEETTDDAQEDENMEEDTSRRSKNGNTQEIEAEEKEDLRETSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5H5</accession>
    <name>A0A8K1C5H5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5H5"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="118"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="34416" checksum="D046DEB5A6C794C5" modified="2022-08-03" version="1">MEEIPKHLSKVLNYEGKASEPVRHDESLWIPSDVVIRPDGRVEFLSYIDNLHPVRYMQLYESIADVFTAFVPLFERVLTYVTGPWSSGSGLFGLHPLEAKLTTGEKVLKTLYPLRGVIQAVIAIEEVQIHPDSISLPDAPSDSWVRHSVHNNIVATGVYVLHCTNLSEASLNFRRMARRPMAPGIRQSEIDEELGAIRCLEGRGVVFPAYCGHKSTSPLQLLVPTKPGSMQVLVIHVLNPSQPVVSSAEVPPRQREWRFDEIITPIARRYALPEDVQKRLETMIPGGFTPEEAVQLRGRVVPSTWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5T1</accession>
    <name>A0A8K1C5T1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121584at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1492"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="386"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="867"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1376"/>
            <end position="1424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1574" mass="184049" checksum="75C1E61B83B7DCAF" modified="2022-08-03" version="1">MLARGKAAEEPNNASADGLGENWKSALCVTSLYDSYVAVQHENEALRDQVRALQHANEVLVAETRNGRRSRAVVKPLPGPESDGSGALDKTDGDEDGVAVFLKEIQLLRTEKSQLELVFDKKKTQLEAELREYKALYNAQLEKYQHKFNLDPNEPRRAALATQALQDTLEKTVYEKEELAMQHRKLQQRFLEVEAELRTTKEALEMSVTKLQAKTVSLAQQRIKSVLEKWVLTNMSKAWKQWRVGVMMDRLQAKEAAVEKERVEQAKRTRKQMQDDRVAKWLVEALQTTTRRVFANWKQMVVLKKRRQAEMKTLSYQQDLRRLRSGFAIWKQTHRVYKTRAEAGQRLASLLNGHKQARAWRKWVVHLWSARLESERHEKEQLHSNLLRSSTMMKEMEELLAKATQEAQLLREQLDRTTEFHEQAQESKQRDQDLWQQKLGAFFLARSSKHLLSQTFAAWHETTLLKIAFRRKTRVLEAKRNERRGRQTIQRWHASSKQRRRCTEIALHVVQRMRMLGVFRCFLAWRSFANTRKDERAMMRRVIHHMSHRQAICCFKEWACYTTKRKRCRHKLQCVLASTKRAKLANAFVQWRSTSKQMGVALEALNRQTLEQEWRQRVEQSKKELKVLRQAFLSWRSTVKNGRKYRQLTSKYALRWRSGTMGKCFETWKLFLQERRVQRECVRRLLSRCGVATLREAWKRWHAHALVSKQAEVLLKLTQERDRQIQSLQWELGQLRIVEAAARDAVLEQEEQHTLAIRDVQLELAAAHDLRRQYKHGLISLYSSIERQRFLKRCLREWKQATHDRKALHLRVDEFVTSKEISCLRQVFDAWKLKRRKNVLLLAAMSMLKRTSQHQICEVITSELEYIRVTLEKKEEITKELQSILEQTQLRLANQEEALQLTAGITKSEAQTRELAAQRMRVLARVFLRQRVLRSTVTAFSRWKWKTCCQVPRVRAAFSIVLHIRSCKQRRAAFLRWKRVSNAHSRLERFRSRRKLATTRIAWNEWKLWSHKRIAIKRKLLLRWLQLSHVKYVELELQKRVHVTFRLWKAQSLCDRLVTERSIVQHALVADNQLQQTRWRRSLLAKWCWQAYHQHCEALRQFFRNGITLSRRQSNTEVRSQVQNLLTQVRELEAEVKAAQFAKTEAGANALKTLQLDKDALDRYSQGLQTLFRQFPSVTSTSELFAAISSGFSRALPASSGILWLLDPLSNELWTTNSIGLGAEPTVVQAPAMLGIAGAVLASNGPVLIDNALHDKRFHPLVDQYALKMTGSSVPVDAIGRHVSSLSTSNSLFCLSIVAADGSVYGVLQVAFQKPNEPSEASKLQTQIQLLGRALCFFVEQMLYEMLRHCRDRLRARSRENFVKLFKQNKNWRKYFVQVERQAQKTEAQLQQILVEQDFLLQEKARLQDAMRLFEEREEQASQEVRDRTTQEYEDLIRLLGISKKKLTKLKQLVDAKEAIIIEKTKEVDKVSEEFAQYRQEVRARDWQTILSHGAPQSKQTHHDKRPTEAASKESSLLHGAEFATIKNQLVRAESDNLLLVKAVDVATKHNGTIPEQLKMEVNRIATRLKKTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C620</accession>
    <name>A0A8K1C620_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alkaline phytoceramidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C620"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006672">
        <property type="term" value="P:ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044219">
        <property type="entry name" value="ACER_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46852">
        <property type="entry name" value="ALKALINE CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46852:SF1">
        <property type="entry name" value="ALKALINE PHYTOCERAMIDASE FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30818" checksum="725A6A4F08F70BF2" modified="2022-08-03" version="1">MTSLRTTDGFWGEPTATIDWCEPNYEHSFYIAEFWNTISNLLFVVLGFYGLWRSVQEGFEWRFHAQFIAVMITGIGSAMFHGTLQLVHQQCDETPMVWAMLVWIYIVYNNEIRKSGLSDAVVIPFLAFLGIGFAIIHAIYRFTTLFQVFFGILASLCCIRMCIHYTQVKDARARAVAISYVRNSLVGFALWMMDYHYCYYMKQLPVNPQGHAWWHIFMGIASYHGPIFMQFVRMEQLEKSPKIYDNVFGIESITIDAPVEKQKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Q7</accession>
    <name>A0A8K1C6Q7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Q7"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="51933" checksum="39706BCB056F6FC6" modified="2022-08-03" version="1">MSTVTREFRALMALALPAMLSTYCFFAMSVTELSVMGHLGVDQLAAVAYSQMSMDFCTLVFMQGFNAGMNALCSQAFGAKNYHLLGDYAQLTALVLTVMSVPMAVLWWNLGDLLTLAGVPDHVTVYARLYCRLSILGMWPRSMFQVLSIYYQAQQIVLPTTIFNGATVVLNFVLAMGLTYGSFGLPKLGFIGCPLGTSLAFAIRLVCYVMYMSGYKKYDRRCPWHWNWSFFQLHTLKTLLGVGFPLALGTVFENAQFQTMALFSAKIGEVQLGSHNSMMELFFFATSPIYGVVNGSVTRMSNHLGAGKPGLARLVAKLAGASIAVLSCTNAFSMVAFKSYIGRIFSDDPAVIDSFKQIGSLGGIAYLVLAFFYYSFAVLQGQARSGPIMIAFAVGAWVVGVPSAYYLGLGRSSQNFVGIWIGMLLGYMVTSSIGFYAAFVKTDWEEQAHLAMERSKKKNKRDHESFETEPLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7E3</accession>
    <name>A0A8K1C7E3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7E3"/>
    <dbReference type="OrthoDB" id="299656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="646" mass="73845" checksum="0E4D326E517FA932" modified="2022-08-03" version="1">MALTSSTPSAQRVVGNHEHKENATFRGQRLAAVPGDVLTMRNLVVLDMSKNQLTRFPGALVAADMPRLEVLLLQENVLYVLEDILALSTSPRLRELNLLQNPLRLVENRVYLLEALLSATTCDEKLLRMVQKDEALKTHSTPVETSQAMLQTASSARKMHHRSDRRRHQPQNATMQYMSRLPRRSGFPMLQKLNTDWITDADIHAVEQERGRPIEYFERRAAKNNRGDLLHRTTTVDRRFDGSRMTAKELLRRQTRSVAIPEVAVIERFQIDVESSAVVDLNDEELVNNKNATDSEDNAATGMTSEEATAARSRDEEEHLEVIHRLFQKSTTTNQKLRRISSTTLLASSSKRVQDEADAHSPTAEKTLPDEHVDPWNHPIQTFDDLSSVDRQYIRHRSRQSVESNLQRDDQFFDSTIFLDCIAQTERSRRLVVQAVDTICPPSASFKNLALYRSFTDSAPTLPPASTAAQQLRETMASKFNVGIDRHEFDKIERFRDKARASGFDERDVQAALSEYFENEHRLQQQRTRQLLSTTCEEPPRYSKAQVESLESAACAMDESLSRTKLRNAVDLANVLLNKKQEKHMIQMLIDADAKVIEEERAALDQALHRHHLELIASNQFFSQSQHETDREWMRRAARTHATKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C813</accession>
    <name>A0A8K1C813_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_014305</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C813"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000018">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="284"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="469"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="923"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="923"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="967" mass="109849" checksum="092F745C20AB6080" modified="2022-08-03" version="1">MIRGRSTPSERERSTREEGASYEPESTLRQSRYNRRPDGPKKEYEDEVEEEFDREFYLNDDVGGYEVHEEHVFMGNQEKFRELEEKLAKTRARGETKLRGMSARASALNADQEAWENNRLLTSGVVAKTRVETEFDDELDARVQIMVHSTKPPFLDGRVSFTTQLEMVSTVRDPTSDLAVCARKGSELLREVREQRERSKMRKRFWEIGGSRMGDAIGVKAQDTTDEQDEEIAEPDDTDINYKADSQFSTHFKKQKAVSEFAKTRTIQEQRRFLPIYQCREELMQVIRENQIVVIVGETGSGKTTQLTQYLHEDGYSKYGMIGCTQPRRVAATSVAARVSDEMGVTLGEEVGYAIRFEDLTSDKTVIKYMTEGVLLRESLREADLDSYSAVIMDEAHERALNTDVLFGILRKVVQRRTDFKLIVTSATLDADKFAQFFGGVPMFTIPGRTFHVETYYAKSPAEDYVDAAVKQVIQIHLSHPPGDVLVFMTGQEDIEATCYVLADRMGKVDGAPPLMVLPMYSQLPADLQAKIFDASDVRKCIVSTNIAETSLTVDGIKYVIDTGFCKVKVYNPKIGMDALQISPISQQNANQRAGRAGRTGPGYSYRLYTERQFCNEMLEAQVPEIQRTNLGTVVLLLKSLGVKNLLEFDFMDPPPQDNITNSMYQLWVLGALDNTGELTDIGKKMVVFPLDPPLAKMLLFSEQLGCSAEVLIVVSMLSVPSVFFRPKDREEESDACREKFFVPESDHLTLLNVYNQWKMNKYSSQWCTEHFIHAKGLRKAREVREQLVDIMKQQKVRLVSCGGTWDVVRKAICSAYFYNSAQIKGIGEYVNMLTGMPCNLHPSAALFGLGYTPDFVVYHELIYTTKEYMQCATAVEGEWLAELGPMFFSVKESYKSRLLKRMKEQEESKSMELEMSTALAKNRSDDVSDVKKLTKKQRMTMATPGRRDPSVTNAKTPLRTPRRFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8J3</accession>
    <name>A0A8K1C8J3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010218</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8J3"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="41038" checksum="8A1C16F0C1809039" modified="2022-08-03" version="1">MGGVWSRVSGQDARDQSIFYRACHMNDKMMQQLRTMGIDKKKLRALYEIFSIMDRDSSGEINLSEFFTYIDVKRTRFSEKAFAVMDRDGSGEVDFVEFVLAVWNYCSFSKASLVRYAFDLYDLDGSGEIELSEASRCIREVWGSEWEQNANAQKVMMKLEAIMRGNPDGRLTITMFQEFAQRHPVLLFPAFQLQTEIQQRVLGERFWRKAARMRGSVNPADLNWKNVEKIAVLSRQASNNFHKAMEEAMDEDTSERAEEMKKGRLNLSFRKATRGKPRVFMDDPDDRRRVGGVGAISTPVVSIDSKDPSPFSKRKKASIAESLSTNEIGVKNKSPTAAQMKRASKQNPTQNKSLRVEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8M3</accession>
    <name>A0A8K1C8M3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8M3"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="561"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="679" mass="73964" checksum="51CA8CF48975C40C" modified="2022-08-03" version="1">MIAWHEWRRYWHKRMPILDWLPKYSPRRDLKADMIAGFTVAVMLVPQEMSLAALMGVPAQYGLYTAATAPLLYPLFGSSRVLSVANASEGSLLVGVMLRVAEIRTMEERVATGILLTFFTGVIMIISGLLHQGGVVSFFSRTSMHGYITATAFLIITSQLPGWFGVPMPSGRLTIFTLFEIFASMGSTNIASLVLGILSMILLTLGKKLKKQLEAVRPLETLTTLSSSEEGRDYQEDTLDQEEGLEEVDLLATELQRDLVRGSRRASVAPTPPPEPSDKPVHASPSAVLTTPSVLQIYLEDKPRVLFLCKLFCDGSALVVCMLGMLVGKTLGEDHLKLTGDVHRGLPTPVFPPAALGSLVPWSRLQSIVLNAAMISLVFFMSSVATGSNLARKGGYEISPNQELFGLGFANLGASFFQGMPSSGALSRSAVNSQSAHTPLASMITACLVIITLLFLTGPLYYLPQAPLAALIMLSAVTLVDFSEPKWLRVVRRHELYVWLAAFFGTLTCGLLRGIAISIAASLFAVMARSKKPRVFALGQRSDGTYTDAESPGMDAIPLLDVVLVRMEHALYCGNASHFIHGIQHKLDGANTQGRVLGVVVDGSRMNDVDASAIHALKEYAQKLRDREQHLTFANLRTETAESLLASGLWEDPRVREKQRLTQDLDAAISCLRAMASSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Q9</accession>
    <name>A0A8K1C9Q9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Q9"/>
    <dbReference type="OrthoDB" id="129554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="39412" checksum="5350D7DCF7D88514" modified="2022-08-03" version="1">MNESDPVGVVDAVLRCLSDNGIEVTQMPQTIVVPTNVEVDEFKKAVKAAIPKLKLKMPVWMSMFKTAMDPLKEQANKTQVSKTMDVATLEQRKREFTQPYIGQDVPVKLCKYISQCWQQYCSKLMGQAYPYIAIVQSSGFGKSRLVRELAVLTNGEADASMRVLYVCLRRGFSSGYPFRTSHWRNYLFPPADGDDETLQNTLSEGLCTVFQNAVSDWANVGKECFQHFENAQAGVTTLAKLRCDAGSVKHTQQPCLKSESKRILVLVLDEARWLLQTNEDDETGWFRRFRRALNLANAEIRGRYGNDAGIFAILIDTNSKISDFTPPPPWIPRVVRYRAAARFSRRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9X1</accession>
    <name>A0A8K1C9X1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007263</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="529"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="598"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1123"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1148"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1192"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1231"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1260"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1361"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="85"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="780"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1387" mass="154834" checksum="F14C21229803FA69" modified="2022-08-03" version="1">MAGSRSDEAPSTVVIEYSSGKELMKHGAEALHEHVSTRTKAAMGRAPPQLEVRVQNLSLSAEIVVSSDAKDDKPELPTVANEFKKRFSRFSAKKHKVTKRILQDLNIVLKPGTMTLVLGQPGSGKSSLMKILSGRFPMAKNIKMSGEVSFNGTPLEDQHLKRCLPQFASYVTQRDHHFPTLTVKETVSFAHECCGGEWLSERTERVCNAGSPQENQAAMEAARALNKHLPEVMIHQLGLEECQNTVVGDAMTRGVSGGERKRVTTGEMLFGDKSLLLMDEISTGLDSAATYDIIKTQRSLAKTFQKTVVIALLQPPPEVFDLFDNVLILNKGHVMYNGPREHALGYFEGLGFKCPPNRDVADFLMDLGTRQQRRYENTESEVILPRKVHEFVARFEQSVFFETVVADLNEPMSPERIRDKEEFYDIVPEFHQSFFASTMTVLRRQGILMKRNTPFLVSRGIMVTVMGLLYASVFWQLDPKNAQVLMGILFQSVLFLAMGHAAQIPTFMAAREIFYKQRGANFYRTSSYVLANGVNQIPLAVLETLLFGTMQYWMCGLVSSFVPYLIFELMLFLMNLSFASLFFFLAAIAPDLHIAKPFSMVVIVFFVLHAGFVITEDQMPDYLVWVFWINPIAWCLRGLAINQYRRAEFDVCLYDGVDYCKKYGMEMSRYSLSLFNVKSDESWLYWGFVFLGVSYVVFMFLAWATLEFKRYESPEHVTLDEEENHKTTNVDQLSASSVSSGADYALASTPTERKTPTQQQLETVVAVAPERQTHVAPVTLAFRNLWYSVPDPKDPKGPQLDLLKGISGYAMPGTITALMGSSGAGKTTLMDVIAGRKTGGKIKGDILLNGYPATDLAIRRATGYCEQMDIHSDGSTIRESLTFSAFLRQSSDVPDSQKYDSVEEALELLDLHPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKVIMDGVRKVADSGRTVVCTIHQPSAEVFSVFDSLLLLKRGGHTAFFGDLGSHARELINYFEAIPNVAPLEPGYNPATWMLEVIGAGVGHAGQNDTDFVARFNGSEKKALLEENLARPGICTPAPSSVELSFAKKRAATNTTQARFMIKRFLDLYWRTPSYNFTRYMMYIIVALLFGLLYLNSNFRTYQGINAGVGLVFMSTLFVGMTSYNSVLPIASQDRSAFYRERASQTYNAVWYFVGSTVAEVPYVITSTFLFTAIFFPMVGFSDADRFFLYWAGVALFVLFQTYFGQLLVYAMPSVEVAVIIGVLLNSIFMLFIGYNPPSSTIPSGYKWLYYITPHRYIISVLVSTAFGDCGEGQEGISDSIGCARLENLPPTVSANLTVKGYVEEVFDMHHDDIGKNLGIFIGCIVLIRILAALALRYINHQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA42</accession>
    <name>A0A8K1CA42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CMGC/CDK protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_004338</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="12">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="107"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="11">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="959"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1364"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="551"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1387"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1403"/>
            <end position="1412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW59269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1466" mass="164550" checksum="6049B709F5B3FBCD" modified="2022-08-03" version="1">MDVDSTPSTAPDDAGLSFEHLEAIRNVQLITRNEYPLPHLTREKLHKADDAYAVCYCTYPRPDEPEQSRCDDVSCLNFATYIECSPSKCDAGKFCQNQRLQHPERFPALEAFKTLEKGYGVRTRAAITQGDVIGEYVGEIIDQKELALRLKSVPRNELNFYYLALEPGVYIDARNKGSFTRFVNHSCEPNCKTEKWTVKGEIRIAVVALRDIEVEEELTFDYQWKSLGSRRIKCCCGSANCKGVIGSEAVAKVELPQGYFRDPKPEEIGSLLEGRRIRLFLSTADTSLFAHAWVKRYVPEDETYELDYEDGSSQTPEDAFDSPSSSGAADELRSQLLIKLSERSWQLYIEPQDFEGEASGTGVFSIPKRRPSGTTENGEGEPASSTNGDKSDGAGLTTSPSQSSGASPSSYSFAARTLVITERRNQDGELVDEFGDIITTKILVKGIPPHYDERKLRGLFVAKPERSSSSLLAQFQRPRLLSEDIVVSLDMFPFDETCRWALVEFTDAKYPSLFKKNLNARNLAHTALRVYHAGRKEIDNFNRAKRHAAIKKREEAAAKDRQENDETKAQVKPLPYSYGRPLNWLVSIEQVENSPSRRQGMPQHVEDALRSKYTKAILRVARQLHLEREDATSAILALHRYFSFHPIVSGNAENMAAGMLHIYLKAHARKFTWAEFVCEAYAARYTSTGGNAKLDQKSDAFKRAAKQILETEKTLLDGLHFDISSADPYGLLESLTMPTKQKPKDASSMEKVEVPAEVQKEAKHMMSEVLRLSVWAHNIVECVVLSLFYVTTAALVAVDAEEMREEDVWTPALSIPAFLPRVDPIGNEKESLALLECALAITDALKEKWVRMDKQAKAARSRDRARSNPDEFDTERFAVQRHKPMEITQRITTVLKRWIGSDRTPSSSPSTQMDVQEAVDSASTKVAEFITFSMLQNNQTEGKFDTNSVDTYPGAGVYFQNSTTRKPGSFKPNDATQSLRLVTNQVENVDQIRKRVYLGTISRDVNAECVGQEVYLQPFPYRDHEDVVTDHTGFSRSCAREILTALVLFARSPRHFIRPVGIVFPADDDNATSTSKTEDGKSASLSVADLAMSDFMDDGEGGVSRRCRLHPSTHYLAFEKPLNVFSGLLESKISIPAHLRKRAIFDMIQSLAICHDRRYVHRYVAPCHLFVFQDGVRLGGCHAARKLGLRAKGDAYEMSESEYREHRSGSWIQVSAPEILLGDRQYTSRCDVWSAGCVALSILVDQIPLLLGSDLKSQLNLIFRLCGTPNIVWERGASLPSYEKYKPKHDYKMRLRKTIQEHRQEKKLDHVDDDAVDLLEAMLQLDPTKRRSAKKLLQMPYFAEFNDTSRSSAVDFAQLPSTYSSQRRRFEQQMTKSSSSSSKRRRPSESSGERRSSSGDNGKHRRHHSSSKRPKDDVSMTDDVPLPSALQHVAGVSLDSAAGDHTSSSSAKRAKLGWGMGLNSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB36</accession>
    <name>A0A8K1CB36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB36"/>
    <dbReference type="OrthoDB" id="93881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453524" description="Ubiquitin-like domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="42134" checksum="1B888FE9754CA8AB" modified="2022-08-03" version="1">MVVKLFCAVVGVGSVFSVEIDISKTVDDLKDKIKEKQGYGFPASELTLYLARDGDTWLNSRDEHMKALKRGELPDRIKSLMHEELQMLETRNLNNDAYFSKTFERAEDDIHVLVKLPEEPDQATGDRPSPSASIHSENRRKRWRELNDILDKNKKAKPNGEDTTSTGYSYVRWGQVKSVLGFERYKQERKPIPDDTFKFLVDYLKYASEAMNGYTDASREAKRYHFIAPVLIMLCSLFDDVKLEVEETVDGNEVHADGHFEFVLTRGKKKICIVEAKKNDFDQGRAQALVGCEAVADREGLQVVYGIVTDFMKWHLYRSGENSILMDSSTLSAKSDELEVDSLRDVCEMIHGALLDHEEECKKENVSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBA6</accession>
    <name>A0A8K1CBA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004968</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBA6"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF2">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="57708" checksum="0C917E58A3FFE17A" modified="2022-08-03" version="1">MDHSSTHSKFSSSMSSLQISDVDSPDACGFVLTDSTIPMVTGYEHTDLLLSAPIKESQIPQPPRRVARGHGSHAPTHTTASPRILGTLSVVAITFFFGCAGPVGSEDAVSTAGPLVALIMYLVYPIVFTFPYGAVVAELCTTFPEDGGFPIAVKNAFGPFWGIQVGYWSWIGNIVSTAIYPTYLMNLMLYHFAMDMPSSVAQYFFKAGLAVLLSLPTFLGTRVVSTGGVAFLAVVSILTLVYIIWGFAAADSFDQLSQVRQQDTRYNSEMNVMENSGPTDIDWFSLLDTVFWNYDGVQMASVFGGQVLIPARVYPRAISITIALTVFCYVLPIPVTVASNHVDWTVLGDYNTYAETATAIGGQTLHIIMIIVNFVSLIGMSVSSVFCESTEIAGMATSGLLPPALGRRSGRFDSPFTSALFTVGFILILVALDTEFLLPVTNAFASLVVITIFAAGIQLRRRFPYFARPATVPGGPYVLAGIAFIPVGVCGVMIVRTLIDSLSSLFTVVGFLVPGVLYSILRSYQESKSAQGQLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBY2</accession>
    <name>A0A8K1CBY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dipeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C69 family. Secernin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBY2"/>
    <dbReference type="OrthoDB" id="5175656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994:SF17">
        <property type="entry name" value="LD30995P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="SECERNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035444495" description="Dipeptidase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="647" mass="71970" checksum="CFEDAEFAD0B41FF2" modified="2022-08-03" version="1">MGFQGLSIAALLLGALVSPSHGCTMIAVGKNATVDGSTLVAHTDDAGGGAADLRLVRVPAQDHPKGSKRAVYDFFGGYPRVVTTERGPHYEPNAELQEELMKPLGFIPQVEHTYAYFDQDYGMVNEVQLSIAESTSGARTVGWPSDLPHGKNLFGIAELSKVALERCDSARCAVQTMGDLAVEYGFYSEDSGDVNNPGYSSSAEALGITDKYGEVWVFHVLTGKDNSSAVWAARRVPDDEVTVIANGFTIREMDLDDPDAFLASPNVHSLAQEMGWWDPEKDGAFDFTAAYGYRDRDPIRPLYVGRRVWRVFDLLAPSLKLDSRLGTVTEYPTYPFSVKPDKLVSIEKIMSILRDHYEGTEYDMTKGVAAGPFGAPLRWDGENKGVTGGWERPISIYRTIYSFIIQARQDVVDSLGGVLWYGQGTPHGTVYVPFSCRQGSVPESYLMGKQSEFHPNSAWWAFDFVNNWSLLRFDVISQDVRAKIAELQAEAIAERQRVEEHAKSLNSTQEMDTYMEKENNEFASSVVTRWWQFAWYLVSKFSDGYITTGEKPEEMVTPGYPKWWLELTEYAKWPGDSFSPKNAVLKDIDENVWHLKTHSMAVKTTDSESHFGPIIQVGCGLVLGVAIGATAMLLVEHRRRVGYQSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM9</accession>
    <name>A0A8K1CCM9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCM9"/>
    <dbReference type="OrthoDB" id="10260285at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="57438" checksum="8EB2A71F364E8753" modified="2022-08-03" version="1">MADVIPAKPTGAADVSKGSSASSSSSSSAARPASSSSGSSSRNGGGSASDRAREEAKRRRAPPGKDATPEERAQYELERKKIQKYKEDKLKARRDHTRMILESHAQAKRRALLGKQSEFLTNLEFRNTLPDLPFDTKFLQYPHEADRLIKYKPNSLEMDYVYEVHEDSNLGLNIDLIDPAKYEVPENPGPLEVGDEQVLMMKEVNAKNGKAKARPSVTWLRRTEYMGTDLSEMTHKFKSEVEIQSALREGTENALAEVVQLSLEDRAEASFRDASNAKTLVHPFKKNLKAAKVWDVFPDQIVAPNKYAILSYDLLPSQDLKGKSVTERESRALLCGVSKKSQGADVVQGSILLPNARDEEEKDNDEPQAEKFGYYREYQLSIDVLENRVRDESQHVIFMLDPESNHFTYADLLHRIQLRKTKLNGDEKRRRGAIVRRRDYSEAELERRQALLFETGGLYDESLDDAELVREHKRRRAGGDDSADEESKSNGDEQATNGAGGDSPAISSGSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCY0</accession>
    <name>A0A8K1CCY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000069</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCY0"/>
    <dbReference type="OrthoDB" id="148713at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="380" mass="41890" checksum="CD7E979965242C29" modified="2022-08-03" version="1">MASTPKLFTPLTLGGKKDPLQLQHRVVMAPLTRVRSGGSGVPPEYAATYYGQRATPGGLIIAEATNITPTARGYFGTPGIFNQDQIDAWKRVTQAVHDKGGLIILQLWHTGRLSHPLNQPDNVLPVSSSSNMPIDEKIMILTSEGPLTMVHPRALETHEIPLIVESYRQAAVNALAAGFDGVELHAANGYLLEQFLHDGINDRTDKYGGSIENRARFFFDALEAILTVVDASKVGVRLSPYSITRGQRESDPATLYKYVLGKLNDYDLSYAHIIEPRGLHYENDLMPKEGATKFFRQFYKGVYMTASGFERDSSIEVVESGDADVVAIGRPFISNPDLVKRFELNAPLAPWDQATFYTPGEAGYTDYPFLKDDEVKPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDV7</accession>
    <name>A0A8K1CDV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDV7"/>
    <dbReference type="OrthoDB" id="1739143at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418721" description="Isochorismatase-like domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28090" checksum="4A13BC8A8E358D05" modified="2022-08-03" version="1">MVQLSSLAVVMCFLATMATTTSAATTIRSVATADPVDCRVGEFCVSPDPFTAITHQDVVNGLWKPRDETLKDYVLAYTSALESSKKFVLNIWPEHCIIGTPGHNIVSNVHAAALEWAKKKKMGIQYVLKGTNSFTEHYSALRAEYKLSYDPATKLNQELIDNLAKASKVAIVGEALSHCVNYSVRDLVANWPASRRKDLYVFTDCSSAVTGFESVGEEFVADMKTAGLNVIKSTEYETFSLSLKSIESFYTCSIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDY5</accession>
    <name>A0A8K1CDY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013757</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDY5"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008669">
        <property type="entry name" value="LSM_interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05391">
        <property type="entry name" value="Lsm_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="647"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="742"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="602"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="836"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="837"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="934" mass="105310" checksum="F5C5942CEEE7EEA5" modified="2022-08-03" version="1">MTSSSSDFSSDEEDALMVDAGYEGQAYADHTVDMEVVEEAEEELQNAAELLDAVKSELSATVVEAIASLLQPNSTVYAYEAYTTALYYLSSQWPEAPSVQRRMHQLRGELYRRFHALYPLTSEMYQEWISDKESMAEQRRLYALSTQDYWSVALTTEHLQRLNENEDEEGITWEVVETAMEESLRTVGQHYTQGHEIWKLCREITSEHFDTLDGDNELDKEQAIRALYVRQMAIPLQQNDLIMSEFRAWNQYNTHDAIERRDQAIQTAEDTQQRVFGPVQKKMNQFEERLAATVSANPPPEETSEQVWLQYLNFGMFRLAPLFKDTDDAHVFMCGMFERAIAMVCLSAALWRKYLEYVMSRGENMTNSENRLGLCRRAVRNVSFDSSMWVDLLLLMESNAASLSEIIACLQKDILARTAPPLMDSAHSVQVLRTVSGVARRLTSTLPTEQAIVAIGHIFALSRSFIESAFPQDSIALASVLEVQAQCYSYLCSKSSHAKTSWSQCWHDILACRGNEAEIWLRYEQEFRFVHSTDPALTRLLREQVFVPAAERVLDYPLSIVDRWLMFELAAGDLVQYESVRQQHVKLSDKLQKQATEAQLAAAESTDYQPQNKKRKAASTHVESSEKRQDKRAKTDRSQEQQFTDDFTLFVCNLSKDATQDEVEALFRHIPSLKDVRLVVKERATHVKSRGMAYVQFHNEEGVAAGLNVNGVELHGQTIKVERSTPPANASSTSKSAASVATTLYVGGMLPPERDPITEDEVQTAINQVMDTPAAVKQVLILRDRRDKPKDYALVEFLETRHAKSMLAKSKVEALKAILGEQITVQTSRMSIAQVVRHRDEQKEAVQKRKETTKKPVAAKTKPPRSQGKAAPHAKPVTRLAIPPVGKPSLLMPRALQKKAPAAAATGSAGSGAQQPSAPKTNDDFRKLFMKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE68</accession>
    <name>A0A8K1CE68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE68"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469668" evidence="3">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="25749" checksum="599039D6F3597DFC" modified="2022-08-03" version="1">MRIRALFVTLGCVALHSASALTTAVRSISSSPAPEPESEPDANNESSVVISSDDTGLPSTDDIKHFLDKLREKAQDNADLETLLEDFQLQSEELIDELSPEQLQDAFQAFLAEFMTGVHQFFDDPSVKDWESLFDGASADASLEDIWDAVTNPEWLTDGSMDWNGLNWIGALESGSVVMEKESSDEDSDGPIETPPEPSNSSFVAPPFATPAPTGQAMHTFGVSLLVGVAMVLTHFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEA1</accession>
    <name>A0A8K1CEA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WKF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEA1"/>
    <dbReference type="OrthoDB" id="10261563at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019327">
        <property type="entry name" value="WKF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306:SF2">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10180">
        <property type="entry name" value="WKF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WKF" evidence="2">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="23775" checksum="84444880E9B430DF" modified="2022-08-03" version="1">MGAAKPSKKQRGKQKKAQKAKATAPVGAGRGAKPVANVKLAPASKNHVKFNEDGEAQPAGGVSVVGKKRGRGAAPAKTTKAASMDEAAEEDQQGGGKSDRSPEMIQSAKYYLEKWKTRNEPTADGEEPWKFKKMKQLWILRWMFEADVIPKSMFSLVLEYLDGIQGIARQRVLESAHEIIDAGTPDKGEEDAEEQDVAARLARRRYKRAMQVAELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEC5</accession>
    <name>A0A8K1CEC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP-dependent glucokinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEC5"/>
    <dbReference type="OrthoDB" id="5847021at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043843">
        <property type="term" value="F:ADP-specific glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007666">
        <property type="entry name" value="ADP_PFK/GK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21208">
        <property type="entry name" value="ADP-DEPENDENT GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21208:SF1">
        <property type="entry name" value="ADP-DEPENDENT GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04587">
        <property type="entry name" value="ADP_PFK_GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51255">
        <property type="entry name" value="ADPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61820" checksum="E8E6340925653CD1" modified="2022-08-03" version="1">MYSVSQLLALGVSVAIALAAVFYADLLSELLPTRADTLSVAEQHQLLSSLVFQTTQKPADDWNDGATTARKPRLAFCCSADLDVSVRAVELMDRVQQVEEESFKHHNAKKHSKRKTYAKTLVKEHHERIGDLRDLQESFAFYFSNGAAAEQSMNSPEQFREVVKFANEIAGVKHKVGGNAATMADRAAVEGCDVLLGAAIGKEMRKHFNAKMQLVGRLEDHEHEDVHLVLEYGKGDQFRGHESPRANRYYLNHDIYNARLSVLEEFEDSLAAFRPDLVVFGGLQLMEVETDETRRLARLTKLSEVLQNLFIKQIPSHYEFAAVSDFTLFDDTVRLVLPWVDSIGLNEQELYILHHYLVTGEEGTATHSRPTVAQISAQINDVIRFAARARTAFQRKQSGGEDENGVEKLALAQLSRIHFHTLQFHISCQRDDSIWADPTHALVQSSLMSTKLACGKNNSDPSVMRPAAEMEVHPERVELLLPRNVLVSQQQSIKVDIDPFNPVVTWREEDFQCHMVPMMACIKPDHTAGLGDNISGTGMAYHYLKKQQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFK6</accession>
    <name>A0A8K1CFK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFK6"/>
    <dbReference type="OrthoDB" id="10261598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004531">
        <property type="term" value="F:deoxyribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004947">
        <property type="entry name" value="DNase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10858">
        <property type="entry name" value="DEOXYRIBONUCLEASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10858:SF23">
        <property type="entry name" value="DEOXYRIBONUCLEASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03265">
        <property type="entry name" value="DNase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419907" description="C-type lectin domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="61628" checksum="CD84AB35BFD739D5" modified="2022-08-03" version="1">MRVLKLGLCAVLAGHRALAQASGDGLYARDGKGQPVSWWVALKLPMQARRGSADAPIDDTPCDCPPPTCTGLDTELRDFRARATGLCYLYADSNTPTLRHFREIGYECLGQGGDDPLSQTLRQIQNNRTDGDVYWALFNDQLNGISQTPGMNGGDNKTVCSGGDLFSAHAKGAVGFDATSGGFYLQTSTPNFPDPSIVRASREDKFIPLGCQRDNNVKFAQHVFAMSLEMPTLNQLGQSLQAARLCSGNFYHGLNASLASANLYRDGKDPERNANFSDIFHALLDPQLPVKEESPTITVPFRSIDHSGRKTDVFKPLPAEQPLVELDTTTSNENVTIIVKTPRAAVPPWALVAQTLRSDMSVASWWDGSFGIPNICAGDDFKQAANHFCLDNAAHGVVLNDDGTARYNIENLVEASWAMDSGTEQIWWHLVGGTRKDSNHAKWGLTTPRNGSAQATYVTFADLNMEGFPCSRACNGSQAGRGGSFISLPSIPLHKSFVNSLGIRACPCVASTTSDESYTSLRMCHFGCWHKLEKHFEPADLPQMSHSASSYWLKNDTRATQIRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFW8</accession>
    <name>A0A8K1CFW8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFW8"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="240" mass="26889" checksum="EA2846EFBE3460ED" modified="2022-08-03" version="1">MQAFRSALSSAQRQGALQRVSSSQRAFSAGAVAVQALSAEDWLQNIKSLADRNIPIKKTKLTSFLKTVTTSEELEASKEIMKIYERKRVDPDASAAGVFVKKALELGAANLVFEVLEANYRIGLFLEPTTLNKLLSKFFKDGEFDKVYQLHEIGTEKYGVKSTDRTYDILIRTAIEQADYDRAVDFMKTAAETSNLMRVTCNNLLFKLKEGEFQDKIEEVATLMKVAGVEPNETTKKILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHC3</accession>
    <name>A0A8K1CHC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHC3"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="78"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="538" mass="60311" checksum="5E3DBA76F24CCA73" modified="2022-08-03" version="1">MLKRWATTAAYVRTWSPQAVWRQVLAKLVRFFMQLTWLARPRLIKNEAVDVVDESVETIEDDKADEKPPKDADEAARIGLANTGNTCFVNAVLQCLVALPGFVARLDDEVVRVASTPSGKRGNHADQLELATALVDLLIGLLPASALSGFADDSHTNGVECSPVVADKATQPTCASKKRKRDVSVTAIDRSRDAHAKRLRHFLQAASKCSDLVTPVASQQEQQDAEEFLGFLLDSLHELLRASPESSTEVAKATLAELGRLVELENECLEYLKNCLVTEPESYNRAVCYLGDIRQRRFLKDHNSFITKFFGGQIVRGSQCCRCANLTCLHQEFRMLSLSIKSNRNSQTLEECLEAHRNLEDLTQDNRVYCDGHCQDKTNRRTQVLVQRAPEILVLQLQRFKQTRWRSRLEKVATPVKFPLGSEGLDLTDNMFMRDSAAPHLYELYAVCAHIGSVLDAGHYVAYTRQSVCANSSEVQWLKFDDDVVTAVDEATLRRETLSTAYLLFYKRIEQVEKTSENSDGGVNAQGDSDTVLIDDRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHU7</accession>
    <name>A0A8K1CHU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005674</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHU7"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000099">
        <property type="entry name" value="Lactase-phlorizin hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035458673" description="Beta-glucosidase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="65861" checksum="6D534B02EF1F3A0D" modified="2022-08-03" version="1">MRHGLSLATLAASCAVAVSATASEQRCFPDNFLFGSATAAYQVEGGWNDTGRTPSIWDDFCRERPGKQCANVADDFVHRYKSDIQLMADTGLSSFRFSVSWSRVMTWDSETKHMKPNPAGIAFYHDVIDELRRKNIVPIVTLYHWDLPSALHKELEPQGWLNSDIKEHFVEYAELMFREYGSKVDYWSTFNEPWSFSYMGYGSGRLAPGFTHSKSNAYVVAHNVLRSHGYAVQKFRALKNEDVIHPNARISIVLNVDYAYPLNASDPNDVAAAERKMHFGLGWFLTPIVSGDYPVVMRERAGENLPTFTPEDEAVVKDSYDLFMLNHYYSKAVVDCKSPLSAVKCSDLSLGWEADLGIDESRLPPDARREGTDREGNYLCPDFNGYPKGYLETIRWTHKQNPKAEILLTENGWCGNETIANEDQLWYYQTYLEQVHRAITEENIPIIGYTAWSFVDNYEWGSFKPRFGLYYVNFTSMTGSKESWTPRSTDLERIPRIAATWYASLAKSKCMDRLPETVSLEEVALVADDTRVSESMLSSNLLFCGVMAPIAIASVFAISLLRRRSASRSTTGTQAEVTPLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHV6</accession>
    <name>A0A8K1CHV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_005689</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHV6"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000004">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="15">
        <location>
            <begin position="169"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="87"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW63071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="54167" checksum="93D2EA45EFA29A7B" modified="2022-08-03" version="1">MPSTTNGTLSTTTASSTTNAKEEENGAGFRVGTILWANWMGQTERTCVVIDRKLVGKERFKYYVHWHDFNRRMDEWINESEVIREGTEEETKRLQEKHAHRPTPAANASGEGTPAVGTPTNATEESAPRTRGHKRKAPEDSHDEFAPPDEHDEHEGMDAASIREHEEVTKVKNVRFVEIGRFRMAAWYFSPFPKEYFPDGQIDCLYFCEFCMGFFCHKRELSHHQEREACSRHPPGNEIYRHENLSVFEVDGAVSKIYCQNLCYLAKLFLDHKTLYYDVDPFLFYIVCEVDNRGFHPVGYFSKEKYSELGYNLACILTFPCHQRKGYGNFIIQFSYELSKKEEKVGSPEKPLSDLGLVSYRSYWTKELLKILRDYPEKEVSIMELTRMTSIKNEDIIATLQYLNMIKYFNGQYVFVVPKQILDEQLNKVTKKGPQVLAEKLHWAPLHLDIKRDKWSLKSKSADKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI13</accession>
    <name>A0A8K1CI13_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI13"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="253" mass="27152" checksum="F77B9228B3D138C9" modified="2022-08-03" version="1">MSCCPVTAEPPRDASPSVGAIKNFGQTTLYVAGPANAKAGVIAYPDIFGLDSGRTKADADALGKLGYAVVVVDLTDGDYLDAATDFQSGLVDWFKKYSFDSFLSVRINDAVQYLKTEANVERIGSYGYCWGSWVGATYTATATPAVSSHVSFHPTWVVENILKGDGAVDKLAEAVKVPQLLLAAGDDPPFVRENGSVHTILKARGDASNVIDFPDQNHGWVHRGDLENEATKEAVKMAWHTAIKFIQTSVPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIB4</accession>
    <name>A0A8K1CIB4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIB4"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="196"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="35335" checksum="16A5E6DC7682D603" modified="2022-08-03" version="1">MGRCAATLGIGLKGSVTIELERPVYWPGDTVAGHVTLRVHQPIETKAFELAVIGEEALTWTTRHKNGSSGTRTMYHERQRYLLDIRLVLAPPGRFTPGDYVFPFALVLPAGLPSSLAYRNSYVSGMRDVDGSVSYRVKTWLPVHGMFKADLLTERSIAILSRPPVQPQLVQANFTRKVDFLGLFNKGQCAVTSTLISDVLTVGQVAEIQCHIHNSSKKRLQYIRACILQDVDLLPGDSWSGGGDVRRINIKEYPGLDPGQASLTVCQVSITPNGRFTGAAYLEPSFQGKFLSIKYYLQVKCKYALSPSATIKIPITIVPAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIW8</accession>
    <name>A0A8K1CIW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIW8"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000862">
        <property type="entry name" value="Eukaryotic peptide chain release factor GTP-binding subunit ERF3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="143"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="574" mass="62781" checksum="D53DC681F1EA9FF1" modified="2022-08-03" version="1">MDGSNQQKKGGLNPSAKSFSFNPSASTWTPSFAPPPPPPAPPAPPAFDIVMPVPKKGSAFASSAPAAEAAAPASPKAPTPVSSPKKATPVSSPKKAATPVSSPKPAPVAEETVEAKVEQLELNDAEDEEEFVEEEEVGDEDPREHLNVVLIGHVDAGKSTLSGNILYLMDMVDKRTIERFEKEAKARNRDSWFLAYIMDTGEEERAKGKTVEVGRAQFDTENRRFTILDAPGHKNYVPNMIQGASQADVGILVISARKGEFETGFERGGQTREHAMLAKTLGINKLVVVINKMDEANWGQERYDECVNKLRPFLRTCGFAVKRDVSFIPISGLMGDNIKTRLDKAKAPWYEGESLIETLDSLHIAGRDAEGALRVPILDRYQERGTVAMGKVESGVLRTGQKVMLMPTRAMTVINQVYINEKPVRTAKPGENVLIRVACGVDDIQKGFVMCAPKAEPQPKAIHQFIAQVALVDTLEHRPLLTAGYKCILHIHTVAQECTIAKLLRPIDPKTGKPVKKPVTFIKQGQSVICRIEVEQSITIETFDSMPQLGRLTLRDEGKTIGIGKVIQLDKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJC0</accession>
    <name>A0A8K1CJC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012922</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJC0"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="31"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="90"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="537"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="664" mass="73525" checksum="294C4BBE74AE1B89" modified="2022-08-03" version="1">MTADLDVHEVPSFPVIQSVAERAHVKGMEQYEALYKQSIEDPENFWAERARENLSWFRDFDQTLSGTLSQGDIAWFLNGKLNISYNCIDRHIPKNGDKVAIIWESDEPGQGKKITYKELLAEVSRIANTMKAAGVKKGDTVAIYLPMIPELAYTMLACTRIGAIHSVVFAGFSSDSLRDRIADARSQWIFTSDEGKRGGRTLPLKEIVDHAVHGLDFVKKVFVFKRTNNILVTLNKHMDVDMSVELPKHRPYCPPEWMDSEDLMFILYTSGSTGTPKGVAHSTAGYLLYAMLTTKYTFDLHDDDIHACVADCGWITGHSYIIYGPLANGATTLMFESTPVYPDPGRYWELVERYKITTFYTAPTAIRALMAHDDEYVKKYDRSSLRILGSVGEPINPEAWRWYYNVVGDGKCYIADTYWQTETGGHVGVGLPGATPMKPGSCTKPFFGIDFVITDDKGNIIEGNDVEGELCIRRPWPGMARTVYGDHRRYLAVYLASHKGLYFTGDGVKRDPEGYLFITGRIDDVLSTAGHRIGTAEVESALVAHNLVAESAVVGIPHKIKGEGICCYVTLVAAAQSSAQSTDQIKKELIQQVRHVIGAFATPDIIVFSPGLPKTRSGKIMRRVLRKIAAGEEGSLGDVSTLADPSVVPVLIANMKEALVGKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJQ0</accession>
    <name>A0A8K1CJQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">THH1/TOM1/TOM3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJQ0"/>
    <dbReference type="OrthoDB" id="71158at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040226">
        <property type="entry name" value="THH1/TOM1/TOM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142:SF3">
        <property type="entry name" value="THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142">
        <property type="entry name" value="TOBAMOVIRUS MULTIPLICATION PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="41169" checksum="1AA36D6CFFB971B2" modified="2022-08-03" version="1">MWAFLQDAMAFLNKICVFGVGHCFYTWSATASAVYCYAAALAYTVSVSFQRGRLGEHGHATHLLPVKRMRWFPTFLIFSYVTRIAWLLLSDMHAFEWVEGVYEPYSYDHMIIRAPFLPTSIDMYVLGVTSFGKLATLLYFSAFTLLLRFWEDVLYLAQRAEKPLARIAANQSVIAEYTRTSTLQMRTRTIFVVANVWIYLVEFVLLVLKTLFPHEDGFLFHADYAVVAIFFLILAIMFARCAYQLRQVLLKIEFSSLAQSIARRVTWLGVVCSVIFFARSLLLLIATPTIEVFDPHRSNPWLFYAIPEILPGIVVISMMTVKKQTATTRKPADEATPLLRQRHDSDETVSPFEGCELRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKG5</accession>
    <name>A0A8K1CKG5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014807</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKG5"/>
    <dbReference type="OrthoDB" id="1914176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="29238" checksum="EF4ABF61C23D0CE3" modified="2022-08-03" version="1">MEPIAKRLKQSAESALSAATRKKQKEEEDLAERIKRLEAELQQSGASDDEDESDAESSSSSDDEDTDDKGAVVNLSAYADERVEALPEHLLPKASASSTNLPEKKRKRPAAGSDLLDVVQWPKKVPFACKPCGFVGKNLEDFQAHRQSAEHAAKQQVAPAVLTCKLCDKSFTSPHQLEEHKAGKWHQQRAKQRKARHVVKVCYDFMRGNCRHGDQCAFEHTETKAMKRGTALDRTKKRVCDLFERTGKCKFGDRCLFSHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKL4</accession>
    <name>A0A8K1CKL4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKL4"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="226"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="7">
        <location>
            <begin position="349"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="52982" checksum="BB457D35A54B0FDD" modified="2022-08-03" version="1">MDPRNPQVAINISANAAGNTLDVVLAREEALHRFRDINWATYTRAGGFSLEKLEISALKEIETIAKPGAEDVNANTVDDFLVDHGRTLASALLKLVKNVTEPTVIKYTLARMEELLPDGLRLRKRVTYFVEEGKALDAAPFLRMIRNDTGYVQYAAARLLALFLTVRPRFEDVDALCQWAVQALKLGPTSNSLNDPNRANVTRAAVASTMVLLRHQKSRVVFVKQGGVTPVVELLKNSQSRAQLSYELTFILWTLSFSEEAMDKFVTANALDALIQQVVAAPREKVVRVALETLQNLLGKLSGHFNERMIDGGLLKTLNNLRERKWTDEDITKAIQAIRDVLIREYKELNTMERYEKELRTGHLNWGLLHTDKFWKENFMAFENKEFDLIRLLIDLLESDDPKTVSVALFDLGEFVRFYPNGKHIVKRLGAKKVAMKLMTHENPEVQKQALQCISKMMVNKWEFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLP2</accession>
    <name>A0A8K1CLP2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLP2"/>
    <dbReference type="OrthoDB" id="160172at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="243" mass="27128" checksum="EBA005F941EFCF56" modified="2022-08-03" version="1">MGAPVSFTTDNTGFIVSLRAEQRDPSFCMGSLIASRWVITAAHCLNKGKIRWVVVTAINSSKERKAGEIIEVERTIRHPKYRVVREKDQLMYNYDLLLVELRMSSVRTPIKMVNFNGLDVPQSIKQAKKATAFGLTLLNKAEVLRSVDHPLHYGKEKCNKLMQVKFTMPSDYVVCLGDKTTPKACLNDTASGGNPVILLPNTRTQRLLGVGSAGVACGYRKNYAMYTEISVNLQFIFQNVPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM24</accession>
    <name>A0A8K1CM24_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM24"/>
    <dbReference type="OrthoDB" id="547560at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="66620" checksum="64F8538406220297" modified="2022-08-03" version="1">MELLELTTCLARADVRLQGLDGVLRLLDSLLDVSARYSMPRAAASGSLRLFDRVMDRVKKAGEDPWLIENWLAKAMKHAIANADLDMAQRVHYYHPGPLEVDSLDSALRSGRLDLVQWLIEHRYDRMCVSKPPARLVATRPFDCCIKMSFGGAAHPGQLEVCRWMVEHGYVTQVGHLVAKAAEAGDLETVAFLVERSDQDSLSSAAVRFVLERGHFHVLRYLHERGWLPNDPPTDTILITSDIATEHESSIAYLQDVLDAKITIDDYPETLASYAQEAWKNLTMWGKMLRAVADGHLEATQWSLARQNARWGSDFVYEVAGKSGHLPIVQWLCENESSNWPSLTPDAIEAIARGAAYQGHIPILEWLYEAHSYKCERSTINNAVANGQLTVLQWIYERDGDAMMTEAIDCAAGAGQLAVVQWLHEHTSVGCTKHAMDNAALHGHLETVKWLHVHRTEGCTIAAMTRAAGADAGHLEVVIWLREHRDLQWPKTAACSIGADVTQWLAANNVMEVSPFAIMDAAVKGRLHTLQVLCALARDGKLDVDVAGCAAGWGHLGVLQWLYEQNPSHFDVESVRQSPFRHPHVMKWLEETFDGVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM32</accession>
    <name>A0A8K1CM32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anoctamin transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM32"/>
    <dbReference type="OrthoDB" id="1936208at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038900">
        <property type="entry name" value="TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302:SF24">
        <property type="entry name" value="TMC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302">
        <property type="entry name" value="TRANSMEMBRANE CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="676"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="861"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="4">
        <location>
            <begin position="247"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="938" mass="105182" checksum="0BDACB7D81CEFD0C" modified="2022-08-03" version="1">MNGTTSSYAPSRVRPFAARDEEDDDEVVDGFSGMRSSVNNWETIEREVEELLNPSEESRSRYSVDQDVEVGAFLSHQPQYQQSIVAKKLLLYEKQLIHRQKAIDKLERLQEHAQTTIQGLRRQLEQQEKDFEDERAEWEQEKTDMLRFRGAGGSGGGGGAAMQLQLRMGASAAALAARRRLTEADQLKQQQMRTQMLHGAAEAQAMLLDDAVDISFTNGPRRRTPWNYFRLWLMRRMSPLEKDVKQIEARFGTSVASYFRFFLWIISSFGAISIPALIFLILHILVLNEVAKVQAVEWTAFAGIAPKVFLLSGYVSFEALGYTVVLVSIMALLLLFTIRKWIAEDRLAKTVEAMENDRDEPKFSKVVLNAWDCSLTSHEQASDMKRAITEQIRLTVEEEKVALTLRTRTRKERHVLYLRRAVAFIVYLVFQVASWYVILLLTTQSSEIQEWIGKKAAFLASYASSIVPGVVTIINSVLPTILAILTKLEKWDDVGFAVKAMVTRLYLAKVLNVLIQLASYALLLDPYFLTRRTSVIDIVTINGPVVRKNVMLAFKPTIYACRAEQVASGLLMLVVTDFLVSKVGALAFPMIQWLIQSVQIFVSGYSRIRRQDRSKVMPASDLTSADGEKTQEARPATGTTEVDASSKLELPSSQVAISERRPTITKYEFQVPQKMVALLYSCTIALLAIPLAPSTAILTLMLHIINFKFDKVFLLHLQKKPTSPWNAKDAGNFFIKFYFCTILIALAFTHFFLSSSRLPKACELQDTTLDASQGDAPLCAPKSYVNGTEQCVIDSSNPSSSYFTDSARECQEGYPKCICSGSRACGPFVKLRNGYSPLILSLVSVQFVSACYSLVLANPIITWGFVGLAILVGFFMRNSLRVSAIVAAAREHEMTVTFASLHSKIKQLETRLRLQTKFNSTTVAPQDPTSEESGWKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CML9</accession>
    <name>A0A8K1CML9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CML9"/>
    <dbReference type="OrthoDB" id="149587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25622" checksum="3094E2F4C8CE2017" modified="2022-08-03" version="1">MSCFRRTQSVTSAPTTKRSSTLTGFVRLETSSVANLSLSPSSQHSTSRKRSTSTGSNSSSSSKAMGARWLYAVLSRGTLRCYARRADVKLQNPPVCEMELDLTPTPENPKAFGFDHECLYVRCQKDDSVVAIRLHEIDKVKNWVTGLYYQALAASATMPMSSSPRGSRSKSVTFVEVPEVSILPETPEVVDKSELYYSKQDYADFLQRWKEDMMDGNQSASVLRLCETCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN98</accession>
    <name>A0A8K1CN98_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2-oxoglutarate reductase</fullName>
            <ecNumber evidence="4">1.1.1.399</ecNumber>
            <ecNumber evidence="5">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008144</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="4"/>
    <dbReference type="EC" id="1.1.1.95" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN98"/>
    <dbReference type="OrthoDB" id="418179at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000041">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="394"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="463" mass="50462" checksum="70F51899BACB12F7" modified="2022-08-03" version="1">MLTALRRHALRPRPAAVLQRAYASVQATPPVSEPATAPVDAGDEALDQYLHRPVTYPLNKVKVVLLENIHPRAVEVFRREGYTVETHKGALSGTELANIGGDAHILGIRSKTQLDPEFFNGIGWHNHRLWAVGCFCIGTNQVALQDAANHGIPVFNAPFSNTRSVAEKTLSEIIALHRKLFLRSTELHQGIWQKSATGAHEVRGTTLGIVGYGRIGSQISVLAELLGMKVVFYDPVKCLPLGNARQVDSLSELLSISDAVTLHVPATSTTKHMINAKTIAQMKDGALLVNNARGTVVDIEAAAEAIKSGKLGGLAVDVFPVEPEKNGEPFDTPLRGLPNVILTPHIGGSTEEAQGNIADEVATKLVRYMNEGATTTSVNTPELDMLPMRSNSMRILHFHENVPGVLTKIHSVLSDYGINVTSQYLQSNPRHGYIALEVEQFHAEIVKRELSQIKETIFLRTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNA1</accession>
    <name>A0A8K1CNA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP proline-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNA1"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="550" mass="61408" checksum="162D1502300134A5" modified="2022-08-03" version="1">MAEEKRALTKNQRRRLKKKIEKQQAPAPVSNGQNDAVEASNAKATTLPNVEIEYVSMDVQKELDLPTDDPAYEELMRVLGKFSSAEELCGQTTDEDGETAEQKAARKGMEHGDDNGDERPSDDENATEKQLSRKQRKKVKRLSVAELKQLVAYPDVVEAHDVTSADPRFLVYLKSYRNTVPVPRHWSHKRKYLQGKRGIEKQPFLLPDFIAQTGIAEVREVAAEEDDKKKSKQKMRERMKPKMGRVDIDYQVLHDAFFKFQTKPKLSILGDLYYEGKEFEVKFKAKVPGQLSDELKQALGMVEGVPPPWLLNMQRYGPPPAYPNLKIPGLSAPIPEGASFGYHPGGWGKPPVDENGQPLYGDVFTKPVEQQHTDENIKRERWGEMEEVPEEEEDDDEETEEGYDEEYRTEQPGLDATGIETPLVDGIASVSSIASGLTTPGGVVDMRKGIRGTDTPDAPQQLYTVLEQKETSVGTSLYGSGHGYVVPGTASSTGTRSETGRVRRRFEDAGPSDGDVSVASSTVSKDDDEAAKKKKKAKTEKDKKLKDFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNB0</accession>
    <name>A0A8K1CNB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNB0"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045096">
        <property type="entry name" value="EDR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136:SF41">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY (PH) AND LIPID-BINDING START DOMAINS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00234">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="202"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="7">
        <location>
            <begin position="515"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="721"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="459"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1025" mass="113469" checksum="AA6174D70A28B5A4" modified="2022-08-03" version="1">MAVRPEDLLLDGDRLHMLLDVICTDYITASYASRENGKKVVIKALQKLSLSVYAGTAHCHVTKVKDAPFLERCKVFYEELMSELEQARQQRLLEREENAAYAETMPQLPLADDSIVKEVLKPKLLQFVEESCKERDRSVRSVSVDQGIASRTPQAGGVVTAPRSASIPAPVSATPGSSTNLLGGTMPAQSMAPNVPIWQAGEIRMEGWLRKKGQHVNLWRDRYFMIRSTPQGTHCLCYFRRKGEKEPRDWYILGPGTVVDEVRESPSKIETKPLFTFRIHPKTYGGEEVDEAPANTPHEAPAALLTPSRSTTASFDMPLSPEGSNGDHDYDPRSAKKASSRKFRNRAAAAAAAATAATAVVLTGGLAGVGMGMVGMGMSAAAAASAGAGAAIIVQNRNKGPIALAAESLETAMWWRNSIVECVAQAEEQWKRYLNWYMDKDHELQQSEDGSFGDLPPASINTSHLSGRPPLSQTASSAPSKSNINRTTSTRPRAGSFGAVPRSIAKTFRTSATFSQETSWKLYSFSTNLRVDVERSQLHMTKTGPPPALRTSIKVKASAKQVFERIMKMESSFYSLNHVIQEARVIEDHPQDHSDVVYWRLAPTFLWPVYVEARDLCLLRYWRMEQDSSYFICFQSTTHNDCPNASTTKAVRGSVLGGGFIISPRVEADENFEECWVTLTIQIDPKGWLDSSLTRSWYYLHAYGVYVLEMITTLTAPPHADTTPRPYLPPQGSVSGGSSASSPIKSPSPASTNDLRANQIIVSDVHYPRLEPFRTDLAIKHSLPPKFWSEPDATSFLVRGPHYLSTHTKVRSAPQPFRLVSVELLKSTEKIRHIGLSSFEGPGLSCVTSDGQPPFIFIINFIIPGPPEYSVVFYFTPEHPTELKKNSVFADLCHELMHGESDTFRSKRLKLIPRIVQGTWPIREGIGTTPAILGTKVNHEYHRGTQYLEVDYDISSSVVASAVVKMVLGYTRDIILDLAFVIEAQSTMELPERVLGCVRLDCVDTLNAVQYAAKKPVKAKDTRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNB6</accession>
    <name>A0A8K1CNB6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNB6"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010463">
        <property type="entry name" value="DUF1057"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533">
        <property type="entry name" value="PROTEIN CBG21859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06342">
        <property type="entry name" value="DUF1057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="37954" checksum="91E8EBD04D3B496A" modified="2022-08-03" version="1">MLRTARRSFAVANAQTARFSPCLAPVSLQSTSRPLNRGLATSGRPPRPVLPEPKELTVGDEYNIKYIDLKPSETSSTRKPTIVFLHGAPGSYEDFKYMIPLLQDHARIIGLSLPGNGGSTVLAKDKYYDRIQAATVGRSALDALTSLCTSDEPVFVAGHSFGGHSAINVTGFNEMEGRKLNVQGLVLLSSAGLRLHRGLRKYDVQPVWRMLSSSLPFVESAGKWVSRFLYTQMWRFPKSGSTEHYVAGIVRCATTDFAVINGHVNSVTAIPSFMAWARDDPLIEEEIFLEVGAMCHPGPRFAFERGGHNIQKTKAAFLADALVQWTQDVLNEGMSKHTRDVVVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP23</accession>
    <name>A0A8K1CP23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003905</name>
        <name evidence="4" type="ORF">Poli38472_003908</name>
        <name evidence="5" type="ORF">Poli38472_003910</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP23"/>
    <dbReference type="OrthoDB" id="165008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="78122" checksum="9A83D13EAF2C9D89" modified="2022-08-03" version="1">MFDSISRVAAAAEHAENDKPTPVKVSLPPEHSKRDTKITWQRVLHLVHRVFVFAAAWWYIIISFQASYASMELLRGHDNSARSGTIFPFPVMASLVGAGPIRTSSLVKTTFGDDMTPRDSSIFVVSDGQAVDACPLSPDNYLYTNEFMRAIFTTISRDTAYNITALDEATMELIAPIIDCTYVLQPNSGITGGRLFYLARERANPDRVFLVVVSLIVQQYSISAQAETGPAAVGMVQVIYDMREPSVTNYYVVAKGFPVEEMEYRVYEYLNTTPDGQWTLRSIPSTKSEFAMVLITSIREGFYIKAPSEQSNINNQVWLAPSTPSEAVGIWHFVYTPVLRDSWAWVHGVQFIIGIRLLGNLVILCLTAYNNLRARKLWIGAAFVSISTSQVLNVVLVLVSWFMNEYWSLHEYSVTVGYAVIGLPDRLIHDTVMHADLLTLYFGACGLIGSVFRERIDPLLAMALFEIGYDRQTRINLLINSHHLHAKIQAFAYNFYMRGVLAPLNGQDKISPMVVQASHNMGKRDYDYVAVCLFPVFLNLVWVVAYAILRKIYRRIFPPKVLIQQNTTGTARSGNEESILAQKRVHTLFELATGAELENRYGLVSDYDTCIFIRGTKFASADGIYSNGFVIANKKYLVQASDIWTIVAMKLLRSRFTNVYVYEVNGTTVQPTALLVYPHTLTVRDLLNLNVSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP78</accession>
    <name>A0A8K1CP78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spondin-like TSP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP78"/>
    <dbReference type="OrthoDB" id="347314at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039942">
        <property type="entry name" value="SBSPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044004">
        <property type="entry name" value="TSP1_spondin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20920">
        <property type="entry name" value="RPE-SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20920:SF5">
        <property type="entry name" value="SMB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19028">
        <property type="entry name" value="TSP1_spondin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477708" description="Spondin-like TSP1 domain-containing protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="5">
        <location>
            <begin position="128"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="5">
        <location>
            <begin position="226"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="5">
        <location>
            <begin position="421"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="58120" checksum="9A141D81C3DD7F3C" modified="2022-08-03" version="1">MKLFVVQSAAVLSVWLSLHVDVVEAQANVDCVVSAWGNYAPCDESTMKQTRTRTITKQPKGKGKACPVLAESIKCKPISCVVGAWSTYSTCDSKGMKSRTREVTQKAKYGGAACPALSENIKCKPVNCVVSKWSAWSECDLDTGKKVSTRTILVKPVDGGAACPELEQEGFCPKVDCKLSEFDEWTECDIETGLKTRERTILTAPKYAGAECEALVEEAYCPKDDCEVSDWTEWSQCDHSIGKKTRTRSIIKPNKYGGTKCGDLIETPDCDPVECVVGEWSNWTSCDLNDGSMHRTRPVEVEPLYGAPDCPSLKDVRYCIKQDCEVNPWSPWSACNKATGNKTRRRTPKIHALFGGSECGALTEEVSCDAVDCELSGWGEWSGCDPSTYQRQRTRRILTHPFNGGKICEGLIEKASCKVDCVLSEWSMWSGCDYSAGKKSRTREVLVHPESGGAACDGTTESVTCDPEDCKVSDWSEWSGCSAKTSLRAHFRDVLSYPLYGGEECPVTYEEEACDPYADPEKAVLADGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPZ8</accession>
    <name>A0A8K1CPZ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPZ8"/>
    <dbReference type="OrthoDB" id="181776at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="718" mass="77681" checksum="F0A6804501A51737" modified="2022-08-03" version="1">MSTQLLLLHPEDVPRDSPVQLAAPEYASIIDDSRPDSVGVTLARSQPATSSDSGSDVEDEDEDSSPAPDGSDVIWVARSRVNQCRVWHGETSIGAPGRLLRRPVHAVIDDAPVYGQVVGYDSAIVSVRHANGTSQVQASKVEEVAPSVVFLLYKATLVKRLAIPAARQAAHSKILDRLLGEGGYQATRQISELLAGIALTKSHPTPQDRIMWIDPATGSDTPCSVGHVIDFGFFRDGNVPLTPGVSLGDRFCRDPLEAASPPQTQVQPSDELDDADDADADLPLATQDTHVAFADLMDTLEAAADVAAAGSRRPPVVSPAPAAVPAPVTVTSQPPVASHTSKRLLDDLSTSDPSIGMRTITALAQYPDLLHHYVSTIGLRDDLSKRRRLTALSDSFPDSEVGERGEGNQGYRPTPSQQAIHQAITSAAYKGKRPTAFIEHARVSPATRFQPHLAIMMLMYHLQFGLCGLSLLNLARFDLAAQLALSGRNAVKQRKYSPSLELPEPVSEPTLSDLLGAVDTLALYVNEFCDDVTQRLVAAAKSFALSLDDYAPWSSDEVHTLAFWFSNVLAAYRLAVEMDLAHGTDTRCQVQSRFAMQDPELSALLFRMSRQGQPLSRQHSRRESSSRSHSSPRGVHHRPQSSDAASRGLSLIANLIPVQSGKRLCLRSISHRRCPSPLSDVCTSPHLGHFTPSKKLDAKVIAHIQSKLGGLRDEFSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ52</accession>
    <name>A0A8K1CQ52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 62 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ52"/>
    <dbReference type="OrthoDB" id="165538at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476933" description="Glycosyltransferase family 62 protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="52623" checksum="65C2AA3BD78C2D17" modified="2022-08-03" version="1">MKTVVVVALFAAVACLASGQTTNDNTQALVSSQEALEAIQSAVAPTGVMFTGELEQLEDPTTEDSDLASDGDFGKANTEGLVTNDQQEFFGHHRRRHHHRGRWGGWGSYGPYRFKFGCDGYGGWAYPLGYWNTFGAAALPAPKGDPFVIKGYRETLRSDIRETTETFPQYGTNERGIHYRLDNDAFIKVGAPDMVLIIVVFNNEDSWGETRSVEDFFQLIATFTHPKEQTSVTMLTSSKSEFDKIQRIMREKIPAYAQFSLLLRNDFNPDSSLTRENRHEDGVQNVRRRMLARYRNYAVVSTLESWHQHVVWLDADVYIVPSGLVSKMVHANLDILEPICMIRDGGRDREYDFNAWVGTRTQPKSAEERKGFVPNPLNVDRISTFAQRPEDYIALDSVGGTMLYVRADIHRQGVLFPHHYVIGSEWSMEGYDGIETEGLCYSAHFLGFHCWGMPHEVIHHYNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQJ1</accession>
    <name>A0A8K1CQJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDK5RAP3-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDK5RAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQJ1"/>
    <dbReference type="OrthoDB" id="340432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008491">
        <property type="entry name" value="CDK5RAP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894:SF0">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05600">
        <property type="entry name" value="CDK5RAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="467"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="61139" checksum="FD4342CBE7A40995" modified="2022-08-03" version="1">MADPRKVPIDIQYRKLLEGLIDRKIVLVQWTEQHQQIRDGLAILYPDLPSSTDKLTKLRVKKLSHEELTYFDCKYIMECLQESPEGANKNFFGQYTSPVLKKWQALLRMYEKNNVFAAEAARLITQNTAFEIPFLKKTMVQNEKLVADNKRKIMDLTKSIAEFKRKLETSCADMGIAGVHFREELQRLPLELPSLFADVAKVICSDDVDAAIEYHTAMQTYLHNCDVPVIATVGTGGSGKKDKGKKSSPAATIQSEEDYVPFDFFTAIKELRTASEAFDSPRSFDFEAEAADIDWDISLADTSSADGATIDWGIETLSEDPTTTVTSDDNAVDLDVPVEIDWDITTDVIEPVEVADVSAIDGSAPVVIETVVDASSRVGLLSDNEFRSRVLNELLELKAFLGQRRQELADNTNVAFANQFQGTSPLLEHQSEEKVKTYQQAVDQAISQLTNKRLQQLVLIKSSDRYLDRHVAALEMLTKHMDKCEREIHAIEDRNMDLVDATSRLQPQIDGLVASTKKLKKELEAALPPLFKGYRVNIVGDVNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQW8</accession>
    <name>A0A8K1CQW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007631</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQW8"/>
    <dbReference type="OrthoDB" id="158011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
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    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="248"/>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="96"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="295" mass="33361" checksum="AAD794581CE914E0" modified="2022-08-03" version="1">MTPKATASYGTFMSSARPVGRLHPRATAWWGSRLLLSWVSPLMRLGQQKQLSMDDVWQLQQQHQAETASRKFERDFETSQSIPTAFFKSFGLRFTLTGLSLLVAMMCSFVGPVVMKHVLSSLTSESYSVTDIAVWIALLVVAQVLQALTDLYANFEDEVIVIEFIGSVKSLLYKKAINLSIKSRMKKSMGEITSMFTSDSDTLLTTAFFVHQFWLLPTQISIVVVMLYNLLGLAAFAGVAVIVLALVLNQFISERMIEIQLVYRKSKDMRMKKVTETFKAISSIKFNSWEDKFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY0</accession>
    <name>A0A8K1CQY0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
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        <location>
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        </location>
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            <begin position="123"/>
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        </location>
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            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
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            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
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        <location>
            <begin position="545"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="TMW68196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1709" mass="192034" checksum="D55B30911BD63999" modified="2022-08-03" version="1">MDRCFQRHTAQVAPNGPTLSADTTRSGIDTNVLRPSYSTDKFLVMRAYCRAVTPWRMVWVCSTLALPALLAATVPVFIPLRHPREGITLGCYVHSFCIIFATTLGGLLNMTAATDFTRADFTLLEMAAVSLIAVLVNALETFIICEVWTFPVPFAFVIFSPFFNINLSVGLLVVVRRRLWTNPIFKRSVQLYNTCMNIQMIQIIIYPAISVLYDTANNTQRILLTIFFPVVKYGLKRLLNRAGRQLGDYQTEVAVSGVEICASLYQSMIMQTVPSTAAMGIIMGLDVVQGMMAIKFFADRQVKTSIPRKNLFDEAERLLTETVVVPGKAADTDQRGSKHGQEHKSIIKNALQLANTAESILLIEYYEVVIPVVNGVFLLIAAQFPSAQFNSRIRPFYHDPVLLSSSLLSLLLYSVLQGLSCVAMHLVMKYRYGISAVAHLSFVLERYHQSILGMMVAWLPIILHFTLMHYGSDFTFRFHFQDDYCSTFALPAFVAATIPVFIPLKHPREGANLGYYFHCSTVTFLTIFGTLLHSTAATEIPSTDFSIFQMVVVSLVAVLLNVVETVVVCKYWRFPVPFGIVVFSPAVNIHILIGLLVVLRQRLWKRPVYKRANKVYSPSLNIQVIQIIIYPAISVLYDKANNTQRILLTIFFPIVKYGLKWLLRRAGKQLGDYQTEMAVSGVEICAALYQSMITQTVPSTIAMAIIMGLDVVQGIIAIKYLADRHVDPLIPRLKLFEETERLLILSSTESSSRMKGEQQATVQRALALANTAESILLIDYYEVIIPIVNGLFLLVAAQLPSAQFNSRIRPFYQDPNQLRSALLSMVLYSLLQGLSCVVMHLVMKYRYGISAIAHLSFVLERYYQHILGKMIAWLPIILHFTVMHYGKSRSRQVLENQRIRLCVAETLSGSCLKRGVPSISRNLKTAPAAFTSADFSLLEMIAVSIIADVMYMIETLVLIKYWCFPIPFSIIVFSPLFNVNILVGLVIILGRRLWTRPFFKRSVKLYGMCMNIQMVQIVVYPAISVLYDMASNTQRILLTMFFHVIKYGLKRLLKRVGRQLGAYQTEVAVCGVEICGSLYQSMIMQTVPSAAATGVIMGLDVVQRLIAIKLFADRHSDPLVPRPKLFDKAERLLTLHPATLHSEPSQPTIQRALALALTAESILLVEYFEVIIPFFNGVFLLIAAQLPSAQYNSRIAPFYHDRDRLGTSIRHLGHCALVVRLGAVPPVDLGMMISWLPIILHFTLVHYGSDITFRFDLNDNTCVTPRRAGLVLFVFPIPSLVCALLPAFAPLQAPSLGPGYGFYLHAAIVVFFASIGTILHWSQASGIERSVFSYKEMLCISFCCCFVQTPEIFLVHTLVRFPVPFLWILTCPLWAVNLGLAIVVVLGGKLRRHAVFRESIGLYGPCMLIQCAQIAVYPAVPMVYSQVETTYQILIAFFFPVVKFLWRQILRRYSRGQGSSSTETTVCGVEICASMYQSMIMQTAPSITVMVIAIVIDTVQSIFSVRMHIDALAVSWLPHKRHLVEAARALSVRSILPAEVTLVQSLEARSKVVRVSVDSEGKRLRASFVAIQSLQIADAAEYLFLIEYFEVVIPAIHSVFLLVASQLPSAQFNTGLHEFHQNSRNLMPNVVSIWIYTLLQAASFAVMHWILKRRYGVPSFTYLAFVLERHGPSIMGKMVMWLPIIMHFTLQQYGTDFSFSFDQDTSKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH2</accession>
    <name>A0A8K1CRH2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007872</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
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        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SMG1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1780"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="9">
        <location>
            <begin position="3188"/>
            <end position="3220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="3109"/>
            <end position="3154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="3109"/>
            <end position="3127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="3128"/>
            <end position="3138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3220" mass="356837" checksum="88066510D2596894" modified="2022-08-03" version="1">MLALQTVLAGDMVPIKQRAKAAQQLATYCGQLPTTPGLYGVYEPYLPHLVSVVVTPIKAARDVQENVVHLLKMLGAHNPRQFAQWCAMHVSVTPSSDPWHVDWCCGLSIAAEVRLPRSVNDQGVEVWNEHTFEFAELGAGLAMVLKLWRSLLDSSSDEVLVKAIVDALDVMLSHRSSVGPTVWSSLVTAKMQPHFVDMADVLIGWATSAATSESMRNSILSVLDRMQDLWTGNSVFCLQLLESFSNDIVTLYATPVLPTDDRVKLNFILVCSLMVARCVPTLALSASGTKPSPVARTLSFAGFTRTRSLSSFYLLRAAEYLISLAESQVGLTLRLSVGAITFLVSEAANLVTKRKAEQSEVIFVIESSSRIASMSLSEAPRSSVAPIDVPNAGHNLLRSDQGDNYCAAVERLLQLKCLGALTHLTKLTVTVMATFGFDGLQFILVRHKLAQEMQQMDAVAYWASCFVLACGYQVKPSENQVSRLSQGLRATIGWAVSNQGRHISGFIAASRMVCAAMSNGAFVSHEVAVELVSGALCILESNPDESKEVARIFDILCWVIAQLSSDYKLPGEEVMRLLARLRCVLVTEDDTLLQSCTKLISVLARLEASKTVQVELADITMGLIRDDNQALTEQVATIVLPYIEPWCLLKNATRDEASTEDALVWSSELAVSDFESVFELLSDQECSEFQWHEVCLDILSHSRTHALSPRRLNRLEEARKVVRECAMWTIQNRLRSHLGGPSSTFSGIERVLQVWAERRQSQEASSSISCAMIVEFVSALESYIMLASDPKFAKVEPDSEAFKIGAFFRANLAVCEDWLSKIRPLAVRISGSIHAIEEVRHHSIASVLSCWKELEAFLDHLSGDELDQPKRTHIVAAVAKLHSALFILGESSCDLRDVDSIKGFQVWVDVFSCRLQQYIPDDGNIYSQSCFSWLEALRLEAELNYEAAVVEYEKVLLQVFVTQKVPHEATVDDNAAFGLFGSVILGCIRRCGACCCLLQQWDQFDHLFLRLRQLTSRFSTIEDEHVVARFTKLCTSWNGLSRATELALPLVSDLPPGLATSPKLSDLTSLSGWEGCVDQVTPRNDESMLIHEAVQLKWSRFRLASYANRPVNCISKQEEHAIFRLYTGTGAALTHAKKPPSFDDVRGGDCIRTTTDAALWSRPVLDASFDQSRDGSVYTGTSIISLARLARKQNNVQLASLLLSRAQALGLSEEEELQLQYEQSLVMIRSNLQSEGLACLGQLCSSMLAPLSALTSESVSEAHLEGLLQLAKSVARVESGDEFVAIEQVLKHIDGNLSSTTHTPGQSELLSARDDLVLRCLRAATTLRPSSMKAWLSYSKWCHERGRQNIDAIISNGGRFELVSAEEEALCFILDQLQITEAARSDITAAFQVIMDKTNVVSGRSENLRRFLLSRVSEEDRGLIEQLVELQNKCLARVLDDIKRAAIGYRSFLFASQQSTSEVSTQSSQVTLTVLRLLRILTRFGAERELAEVAGEALIAGPMSPWTRIVPQLLSRIGHPEKIVSTSVAKLLKRLGRQWPHLVVYPAVVESRKGEKGELLTETASLLIKDVLDDLRRDSASLVNQVEQVVSELNRIAVLWDDLWLTTLMKMSTDVSRRISTLEKEELRVDKNSTLTESEKLQLARRKSTAIMKPVLMVIERLWNETIGRTKTGYDLSAHERTFLHVYGKQISSAMRGFHSYCNSDGEDGTKSAATTPLEVWSPFAELLKALIASAGRRERLDLAEISPVLHGITHGRSSGIMPGVVGNVDDPTPVTIKDIGRNVRVLRTKTKPKCLRLEGSNGKTYRYLLKAREDLHLDERMMQFHSIVNELLRSDRSSRDRGLAARHYGVIPLSTDAGLIQMVPDVVPLFQIFTTRAEEGHGGIAPAVRLDAEESVHPAPQPPTAAFYAKLRQYGVNDVTPNQRPHWPAPLLRRVYDDLVSARPKNIIYHEILSQCLDFAEVRQRISRFSRSLAVMSVVGFVIGLGDRHLDNILLCAHTGEVVHIDYNVCFDKGLRLKVPEIVPFRLTPMLVDALGITGVEGRFRTAFEQTLRVVRKGDSREALSTLLEAFVYDPLVDWIKGGKQAKKSDLVKKRLEVNVNLSLFLSRAEERRQLTIGFGEAFVSALSSLSTAIEGSSSSLAGAIPVYEQYDLSVRDQRSRLLAADDLGTKIEQALSRCGDESIYTRLNEVEARLEVFVKECLSRHEQIMQWRSFVMATQIPSSSLILKNARSQTFGRVFSDLRSMIESQHTAASTPGWETVQDELNTKCVAVDALIGSLIEDMAGLMHHMEPLFIAYSEYQRDVNELILHHSTSDVYGLWGKECALVLWLVRAGKLQEAVKLISRASSFSLARDLPQLYVDEFDTIEQALQREISCVEDQSVFIQQEPEVIDRLVQVLFGKPSAMKLSNSQSQRVMKLASAWCFVSLLDQCNSSEAPADFDESFKRLSDVAREVMLALDISATAKGSMKRMNAEHLLQVVDRNKQMNEPSKFIRVLCAYLAVLESVECLSSVLYKELLVKFYVLRIGRQIRGGEVRSLRHQSSHGGVLPAGSTEYHEIINALHELVDKIDDLQITVAQVGIDGGLGGCGDTWFEACLAHIESVMEEAETGRQSPPDRILHGINSQLGSLLVKTLQQPLVRIITHVMETEWNLQYTSGSSDDGIITKTIEDEALKILPSVAQSREDSLASFQQLCQLLNDVLVACAYRWHVDSRSTSLSRRFAFLHSMKNLQQKRVLFMQWNNEEAAPDQMNRHRTLDIIAHTTATKVRVVQTCHHLEAYALELAQQLEYSGSRTLGGEAISFSGRVQALYNSMTRLIEFARSVADTAQGIEAIESSTGQACRFDKNQASLEVDKVGSALFDDLSGLLQKIATLESSQTVKSFSSLKEELHSAQESVATVTAISRNRKAALERECSRYNEQIRQTTEQLLVASRKVLMLLSSFQQVKAVDAAELDSASIEGHQAHRTHAAVADAAAVSSGIWQSFSFSENQRLARILLRNVTGAPSLQELRSILMEYETLDGRLCDVVSKLVPALGDFVDSASSGLAASDYELCVAAFSRLVGCLCSSNVEGSSVSGDLVVAGQELMSKCIHVFYTAAVMADTLSKKAPAEGEATERNSTESHEGLDESSEGEDSSDHDEVAKELGESTGNDIRRVAQVQEANTLGLDVVRRIEQKLYGFVTESDESPLSVEEQSSWLINEATSADNLCVMYEGWTPWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS32</accession>
    <name>A0A8K1CS32_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS32"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467009" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="178" mass="18577" checksum="2FB06E00BCFADE75" modified="2022-08-03" version="1">MKYSIALAASLAALVSTIEPISANSVAISSDAKLPSPTEALDTVKNIDLPKGITLSGTVEPIQAPASIKDAGTDAKNKKESDIIDNQIAIADDKQDHQDHQEWYGRGLGWGVGGWGGLGWGGWGRWGGWGGFGPYRFGYSCGGLGGWAYPLGYWNAFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT44</accession>
    <name>A0A8K1CT44_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT44"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="50964" checksum="D52CE5317E1E5DB3" modified="2022-08-03" version="1">MTKSAGMRVPVALLALYFLHSFFQTFPTTAYGKWLFNVIHMAPATTTIYFSASFFPWNLKPLYGLISDNFPIMGYHRKSYIVICEIGAALSLLITGTYISSITGAFVVRILDAIFEAFAQIMLGIFLVDLAAGDSTSQSSAQVQSWANGTKNIASIIALFVGIPLYKNQSISPQAVISWTSVFPILAAVICVVALKEKRKSSFAMEPMGEPKVTESLPSNSRCGVVTAAWTSFKDDATEKFKIMKPVLPTMLFFFLCSALPDDGTVWYQYTYELLQGQEECLQYASLVGMVGRFVSCIMYAKVCSGRNVRHVFVASTVSSVVAGLPRLLLTPPVANLPISVCTFGTIEAFITSFTAEFALLQLLVVATFYCPENREVHGLTYALYLSFMDFGGVVSGMFSSVLVTALGIVPDPVTQVINWDHLWLLVVLSALGQLLVLAFLYVLPEKVDGGVKAAEQEPLLAETRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTM2</accession>
    <name>A0A8K1CTM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="4">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_006186</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTM2"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="11">
        <location>
            <begin position="145"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="383"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="48827" checksum="D3350DCB4620795A" modified="2022-08-03" version="1">MPIQKIKARQIIDSRGNPTVEVDLTTEHGLFRAAVPSGASTGEFEALELRDGGAAYLGKGVQKAISNVNDIIAPALIGKDETKQSELDKYMVETLDGTKNEWGWCKKKLGANAILAVSLAVCKAGAAARKVPLWQHIADLAGNPTPCMPVPSFNIINGGSHAGNKLAMQEFMVLPVGATSFSEAMQIGCEVYHNLKKVIKGRYGLDATAVGDEGGFAPNIQENSEALDLIGEAIKISGYSDKVRLGMDVAASEFYTGKDDARYNLDFKNANAADKDKLPADKLIELYESFIAKCKGSSPIVSIEDPFDQDDWDSWVKFTARVGQEVQIVGDDLTVTNPTRVARAIEKKACNALLLKVNQIGSVTESIEAVTMAKKAGWAIMTSHRSGETEDAFIADLAVGLSAGQIKTGAPCRSERLAKYNQLLRIEEELADKARYAGNDFRNVDALGKYASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTV7</accession>
    <name>A0A8K1CTV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HECT E3 ubiquitin ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042469">
        <property type="entry name" value="HECTD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010606">
        <property type="entry name" value="Mib_Herc2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037252">
        <property type="entry name" value="Mib_Herc2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06701">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159034">
        <property type="entry name" value="Mib/herc2 domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51416">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MIB/HERC2" evidence="5">
        <location>
            <begin position="3581"/>
            <end position="3658"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="4">
        <location>
            <begin position="3917"/>
            <end position="4262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2481"/>
            <end position="2503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="2">
        <location>
            <position position="4225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4270" mass="470595" checksum="E46269FFD13089B7" modified="2022-08-03" version="1">[encoded data, 4270 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUX1</accession>
    <name>A0A8K1CUX1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUX1"/>
    <dbReference type="OrthoDB" id="129471at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="250" mass="28538" checksum="5890A9C9A973567D" modified="2022-08-03" version="1">MGATYRQGLVRSKYYFFGGNAHKMFASTTAEAADSILDALVRDGTSGVMVVSERGRLEIPSLYAPVLLAIAWEVAAFRFSAQFTLIDLEKQFSNFPAMVEAFFFTRLTLCTGVRVTDQGREVHWPMAPVQILEVDQVVQWATCNEPLWIKPLTFDHGGYNAIYLDKSQGLVRLIQIACTHDYELRLEWFTQCVRAVSRSWTELRSVEVFVVVKRKELAKFKFAHVSGGELMRSFPGWETNEEAPERWICF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV38</accession>
    <name>A0A8K1CV38_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV38"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56645" checksum="F03866920726E7F7" modified="2022-08-03" version="1">MKFPQPHSPFPPLQLSPAEIDSLLQLEETLIDQTIAEFDQFAYIQNRVVDRTKWKHATTRDNLQIYSAIGDHSEDYHLIMHEQLLDSSASTSSSRTMSTSRMDVKGGMRLMGFGSLVGNINDFLFCDVTRSDDDMQIRSSYVPDGCIDWRLLLTLRGATLDNPFRMSTIKYHVKGIQGATGIGVRPRDFVMLDCAGEKTLPNGERVGYSIYHSLDIPGCEPREGMVRAQVSCSYVIRQRGSNSVEIYMRLLCEMGGNINDSIATLTIATAYAGVWMTPWGGQNKKLAWMLKQQRRNGSKKQSNPRTSDRCHVCKKSFSLLRSATRCDLCREHACSKCLIARKISYVRPVRQLVQVPTKFCKHCIMQASLIDASEIARKENVPKEVASRSEGNSDASSNDSFRKPHSDSHHSVGSDDSSPSPSSGPSDITVETVEDWEQAQANPRGTVYSYSSDDPEANQQASVNVDDYQTQLWMKMEQLRLTAEQTYQLTKDNERVMHGARLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVC5</accession>
    <name>A0A8K1CVC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVC5"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="8">
        <location>
            <begin position="67"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="342" mass="38822" checksum="0B6C95B930EFA993" modified="2022-08-03" version="1">MAKMATDKKRGDLTRHSENGQARPHNDVPNKKRRINRKLPKEHRVGNFRSYYNYRLGQAQAGALEDDPRLSVLQQEWFQGKRGIDVGCNSGDVTIAIAKRFAPSYIMGVDVDPQLISRARGQLRDLVQKQQVEDAFRAIAADPSADSQDKSSATDSTKDTEAKLLPKDGSAEEAAATNVFTDEMPLSFRLWKPPQQPKHHTPQDLGKASRGDEFPFNVVFKREDIVNDKHVGTGYDFITCFSVTKWIHLLNGDEGIQKAFRLFYDLLAPGGRLILEPQPWKSYHKRKFTSETTEVNYSKIQLRPKEFPTFLVETVGFKSCTFLQVCQTSAKGFKRPIYLVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAX9</accession>
    <name>A0A8K1FAX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAX9"/>
    <dbReference type="OrthoDB" id="10253098at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="47428" checksum="77928D088F7DB703" modified="2022-08-03" version="1">MSEELKRDDDDGSPPAKRVRFATTTNTNEATHLAIVTDHAQLRGDNLTYFSPAFTYHAFGKEEQIEGYDNLRIEVLFNAFDFSAWLRIQCKDQETRSEDIRSKLASSLPPDVTEDQEAFVQKLKQDADSDFTPPGTLVSSYQRQVDGTEQLFEIYECNLDQNEAAQKLHENLQTLSLWFIEGADGIDVSDPRWVVYIIYERAPSPIVTAKMSFTPVGFVTLFKFRNPLGRKSSSATETHRICQALIFPAYQRQGHCERLVEYIYGQVQANENVYEVTVEDPVPGFSKLRDLVDLAHCKRHNFFSLAPDASTSAPPGHGTASLKPADIDAVQQVLKITQRQVQRCYECFKLGWIDKADEATYKAYRLEVKKRLFKLHAEDLEGMASSERRKAFLDVEFRNLEAHYEQLHSKLNLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB84</accession>
    <name>A0A8K1FB84_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002925</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB84"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000133">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="28228" checksum="33C98107B5579A5B" modified="2022-08-03" version="1">MADAAAQGGERRGFGRGRGRGGRGRGGPRRGGREESKEWVPVTKLGRLVKEGKIGSLEEIYLFSLPIKECEIVNYFLESSLKDEVMKIMPVQKQTTAGQRTRFKAFVAVGDNNGHIGLGVKCAKEVATAIRGAIILAKISLVPVRRGYWGRMVGLPHTVPNKVTGKCGSVRVRLIPAPRGTGLCAAPAPRKLLGMAGIEDCYTSARGHTRTLGNFVKATFYALRATYAYLTPDLWEQHAFGKSPYQEHADFLSKTAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCX4</accession>
    <name>A0A8K1FCX4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elicitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014718</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCX4"/>
    <dbReference type="OrthoDB" id="10454103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00948">
        <property type="entry name" value="ELICITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482412" description="Elicitin" evidence="8">
        <location>
            <begin position="17"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW54947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="175" mass="17082" checksum="1D09634087F93CB2" modified="2022-08-03" version="1">MKAALLVSLAVASVSAEVCDLAKLSIEVGTIVKPAFSCKDASGYDFITPTRLPTDADVKAVCSSPVCQELITAAKGVALPSCELKVGTTGTIPINELFAKIMGNCANIPVSSSTGSASGAGAATDVVVPPTSSTETASGSEEAGSAVSTPAPSSAMTATLGAAVAVACSVAALML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCY4</accession>
    <name>A0A8K1FCY4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCY4"/>
    <dbReference type="OrthoDB" id="427735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451415" description="AB hydrolase-1 domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW54977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="648" mass="71603" checksum="63A79BF85B667F74" modified="2022-08-03" version="1">MRVHTPLACALSAFVAVAAQEPVTRSSGSEGLSINGWYPCGFSNPTPFRLDESSSLDIDEKLPFECAEVRVPLCYEGICDSDSEIDVFVKRMVAMEDVGVGTSVWMLQGGPGASSAGMEYPMMDVYTRLNGTVSVYTMDHRGTGRSALLKCEAAEGYSAGSPGGVGIDFSEVANCVKDVLYQIEGQTAAFSVTSAAKDVELLTRELNEEDDVFVYGASYGTYLTERVMHLAPANIKGYIVDGVVSEALSSFARFGSNREEPGRFFGELCDNGTVCRTKYGNDVPADQKMYDAWLATYQKLDEAKVGENTCADMLRGINEDVTPSDLLRIMFASDVSVSNPWSRDTIPAVFQMLRRCNETDVRIFRSILDLPQGSSYNDKLNHMDETIQSFDAVNSNSDLLMFLIKSSELWTYPSPTWEDEKELDDKGVFTLSMEEDYSWHCVLSGNWSDPTCPALSYYGQQQLPPVDYSSIELASFTYKPDQYYRKHARIPDGASVMVMNGKLDFQTIHLWAVDQYENMEGDNKMLVEFENGPHCPGYSPTTAEDDTNCGARIIASYIAGGGDVVKTDTSCMAELPAINFESDDRLNYFAETTGGSMEDASQVGVEVGDESNEGDVESGSNRVEATHKLKHKHKHMKRTTKHPRRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD03</accession>
    <name>A0A8K1FD03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="8">PPIase</shortName>
            <ecNumber evidence="8">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013799</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD03"/>
    <dbReference type="OrthoDB" id="2083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000015">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001289">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="10">
        <location>
            <begin position="6"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="243"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="333"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="382" mass="43614" checksum="4B947BA8D765F532" modified="2022-08-03" version="1">MSVLVETTLGELVVDLYVDACPLATRNFLKLCKTKYYNNVLFFNVQENFMVQAGDPTGTGKGGMSIYGQLYGEQARFFDDEVRPQLKHNKKGLLGMANTGPNTNGSQFYITTRAEDLEYLDGKHTIFGEVAEGMDVLDKINALFVDKEYRPYQDVRIKHTYILEDPFPDPELLQVPPESPKRERPEEETVEVRLAADEKLDDDEGRTEEEIEKSLREKEAKSRAVVLEMIGDLPDADVKPPEEVLFVCKLNAVTESEDLDMAFCRFGPCKSEVIRDSKTGESLCYAFIEFQEKSHCEEAYFKMNNVLLDDRRIKVDFSQSVSKLWNKFKRRPWEKHSKGDGDPYASEKRSRLDVGKNLRLKQTGRQGDFDLKSGSSQQVIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDQ1</accession>
    <name>A0A8K1FDQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase 123 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDQ1"/>
    <dbReference type="OrthoDB" id="161881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025150">
        <property type="entry name" value="GH123_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13320">
        <property type="entry name" value="GH123_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 123 catalytic" evidence="2">
        <location>
            <begin position="390"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="781" mass="88501" checksum="D0A0BC82F24CF693" modified="2022-08-03" version="1">MEPTPSSSPSAAASTAFPTPRNSLDAIDLQSPSVASKSAFSAVERDDDDANMSNDDAMSDGSSLGIDGHDDAGNAASLALDYDIMAYMLGRTVPQQGQQMASPTKRSASFSDLFASSNGSSRHLSRPASLNYIPTSLSSAPPSGTSPLSLWMNSEWPPPISPQRKRRRQGLWLHAQFAPAMTKSVRRLSPPREIFPDLEDDLMNGVAVSEPSDGRRRRHRQPWGVPDAPSYQDPEGKYVVAARNEVIGTQLRVLASAPFLLTTDSTNWFLPEGHTPRCRVQIERSYLPQAIQIETFLVGYVEDENGDELTETLDTRGYSETQAVEHIVYLRLRVGSDVPEGTYEIPVRLYTQLPGFAFDEALSWTTTLHVRVASTLLPSPSQWRFHLDLWQHPTSIARLHRVPLWSDAHFTLLDRYFALLAERGQKCVTVVVTEMPWSGQQCYIETQYPSALFEHAILDVYESDTSSQDISEGIHVDFQYFDRLIELAEKYHMAHEIEVFGLVSIWRDAANGFDSPMEQGSGSGESDSGETDKSQSNCFDSWRIRCFNRSTQRFRYLRRVKEVERVITLFYEHCVSRHLVDRVRVCADEPSSVPLFHAQMAWITRLAPRFQVKVAINHMDFLQYAPPQVVDIVPLLPLVCADREATERWRDQVHAKQGLDGFPIETLRFEALRIAVQRFELLCLAKSRLNPVEMTKLESELSDILWRTPDRAWFGRYLDERRQPEDLYTLDPTDYERAHALILETLALVDARERRTDTTTDVLTSPSRKVTKRPSFPEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDQ5</accession>
    <name>A0A8K1FDQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L7a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDQ5"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="131"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="29383" checksum="53300EDB9BADDFFA" modified="2022-08-03" version="1">MPSKKVKKTTSTTTTAKTTKAAKPSSGKPVKNPLFQSTPKNFRLGGDVQPKRDLSRFVRWPRYVRLQRQRKILYERLKVPPSINQFTNTLEKNSAADLFKLLLKYQPETKVAKTERLRNIAAGKEEASAPPATVKFGLNHVTTLIEKKKAKLVVIAHDVNPIELVIFLPALCRKFDIPYAIVKGKSRLGQLVHKKNAAVVALTHVNKEDKAKFDSLAQAFKAKYDDAAARRKWGGGIMGLKTQKKLELRAKAIAAEAAKKAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDY8</accession>
    <name>A0A8K1FDY8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDY8"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="44502" checksum="D8CC79CED93F64B9" modified="2022-08-03" version="1">MGVSVTDKLNDAKRHGDLHLSCYNLARCPPNVFTSAELTKTLWRLDLSCNLLTTLPDAISSLIALQVLWVNENPRLTQLPPGLAKCKLLRVIDASSTALDTLPSDLARLENLHVLDITDTPLEKRWIEKKHLPLLEDSTNQIALPYTATAQQEMCQRILHKLKRKDERTRLKLELFDKLYDQVYRMERSNISGCDLLRLTIRRLMKQFPLADEIRSITRNAERFFPASFSTQALAAVDASEFRRAFDRLHEENERKKRAADLEIKIRNLYFDRIDPRAVEPMVKSIYEEIHDLSDVKFLLKHASALFPKDSKDVDGKEIKRRLAALQEEQARERAMAIDKLLIALKSIYSDVEPAQLHDVVSRVTALFKVVSSNIGLTRDIAHIFLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX1</accession>
    <name>A0A8K1FEX1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10287805at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF36">
        <property type="entry name" value="MYOSIN HEAVY CHAIN-LIKE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2177"/>
            <end position="2259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2857"/>
            <end position="2956"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1944"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2612"/>
            <end position="2684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2716"/>
            <end position="2778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2194"/>
            <end position="2206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2857"/>
            <end position="2873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2883"/>
            <end position="2892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2913"/>
            <end position="2928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2941"/>
            <end position="2956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2956" mass="332161" checksum="80F0943A8D950089" modified="2022-08-03" version="1">MEQLQELYANEVHMEELAAREALLQSMCTSSITLFRYCTSRDRFFTAVKALVTQYLPASTARLYQVEKTRGDGLSLVEQDARYVALNEEDTVRGIAGQAALGVSMLTGTQWDALQSRVVVLTRENDLSQSQASIVSSTPSEQDSWIQRHLEFALPSSHGHLFLLLPLDVAYRSAGFHPDVDVAIKRRRDLVSNEPQLLVAVLRDAASLPIGVFEALISDKNPVRMEFLDAFSALLATALEARRSICRPTMQSLEIVVSKRDEADPRPVNPPPVWTAEIADGVNLLVFGEETVKLPDDQLLLEALQAPLADMWAAKIEWEQKVKTMRRVSDQVQILWASLTSLNKNEATASLASVRYQRLRSMIHRMLQEIGLDGVGVRVLFVDESVDEFLASYSLEPAPLSVEGQYSVLRRVIDTGERFESAGNVVALSIPAPPHEDSFRAIAGVLLVFDEDRCTAHSRELTTATIFPAITSAVRLNVWLHQYAVYTRSVEQSLAIRAEAQAQLQCQLDHQTIVTKLYGALAQCESVDKLARCVGSTDLDGTDVTGMTLFVAETRGQDEGSSVSEIQSIWTIDGLSDQRVQVYDHDRPRAVKGIAAYMIDASAPLEYSTQHPAYDSAWRHGRVQNATFYYAVTLRDSASGVLGVLEVAFDTRTTQEHFIQSALKDDVVVVITGFLTLHQHWAREHRALDRRQDDRLADQRSERQSMGSFLSNMSLLPLANVDTWAIEATALLHKLVAEAECVKLLVMAKETDQPLIQSIQTELAATSSQLSTTLNLLHHRVLRTIKSIPLSSDNQILGILVLSKASDEPFTGMALSLAEMAVQLLAMQLRQLERHTKYSDERTKLISSKVEQEEIHSAMHEQLTKLQRREWQSQLLSRLWTVIDIQAQAQSDLVRSLLSLMNGRQHRQESPIAIEMDAFLLIPTEDQVEWLVQSDKASRDLSICVDDEDNESDEGGLAPQLAQQLCRFVERDGKMPHSHVFTAPVNLPSSNGDADGILGRLVVLSAREDDVDELFVRDVARIVEMHLHMHNEIIHRRQFQKQLEERTVEADKATAQLNEVERSTGQWNKAWFELLEGLDPIDSQKTITLDILTSFALHELQHIVQSCFNVQSVKVWLHESSEPCQEIISVLANTDTTWGRHGTVELHADDGLYMARWKRQSKSSGWDGVLLVRWMVQSVADRRALPVSMAQQLTRMTIQLTLLASVAQDACSLRRRLLAADSHLSDQAQLIEDQTRMNDNLTAALHCNQRMQTFVLRLLSSNPHIASDDLYVSVFQTMEELPEYRLWILNKDNETLWMNRHGVKHVMALDASPAVPAVASTVNLLVDDVCVGRLERLVEGDVSFNKLHVDEMELLAGALRCCLMGHQSSCALSSKDREIAQQQHEASTRLTTAHTRQVVAFNQLLHAQATCDAVPTAQIQSDNEFIAAFEKQLVQDGHPLRLAVIDTDYVTGRLLSVVMNGDPVTSLLQWSQWASCLGSWGGEHLKCQIIDDEERLARFPGWKASSRTDNTHRLIAVVHVRQPELDTEPTLHPAKTIVATKKLSEDEDPAMTARVLESVSVKIASCYRSWLQQRANQSRLDEKARQWEDIKLEVGTAQDWARYAQLSLESAQQMLNAGVEALLDDADAVTQRSRILIHVRSFLQLVCGCERAEILLPDAQRHRQDDESGYSDKTQLMQSLVAPNGVPLATIRLQWMSEDERCRAQSVVDTAMQWSSAMLALLHNAEAQYDQINTLLTRVETLSVGNGQLELEGVAMKGLLHEKEHRRAQLETSVGHLTSVLAQARGFVEATDSVEDSNALWHVLINEALRDIDGVYGSSLVDRSTGHNVRNTTLSTTENDRVGRCDDVDAAITKCLRTEATQTLPMLWNPEQGDSKQVWVVPVKKSVDSQLVLLIFTRIDRGAEDCSGLQTSFELLVSMALQRIELMESTQVQTLANSALTDSIQELQRQVAWKEEAIQVEQRRRQRQEELLAGLNDELLCHPVWKTAECDPTSVPTARLVDMWQFLQDLTQERVKRTLLGDMEFSSAHLYGVVSHKSSAAAALLFSLPPDTTKRAFQSIRWGDLQQRKEGQTLIRCVTTATVVASEERMTASCPDDQAVVSGGVTLYFPIRAQIQLEQDEDARKRAVAGVLVLKLRGGLDDQLIQSDECKLVSLFLANLAPRLQWVARVLHTKQSERQRVKRRSTIEVPQPFPSATQYQDTSYRTPVSAEKEDLGAMPSPYEGPVRPTWSRRNGDDEDKSSNQDEMETPAQGYDSDEDRKEMQTLMKRHVSASSSIIDVLSQIQELPLSPPEDDKALRALVVRSLPEIWSKSSHEESVKAGNVSCDLFYLVHGALSTSWSLDAEPRSFGNDPTLSPPLWLQDFVQKVATKRLTFASTLPKEEVWQVDPIHWILAIQIDTSSLTFGLVTFGCRNVGKVIRDQQSMLQLGKSLRSHWSHQLKAAVRRRQDEARAQQRLESVRGELNTAQLALNAAQRLNEREVRLNALAYELLKVEHEPALRQIISTTLKEWLACDQIGFDTSSSDESAVNAGRGSGSVTFESVAMETVMRFRFVSPIVDGSGQGIVYATLIARLGESGRAALSQDQGLLDQLRRFTEVVGCAWHQLAQRQLLERERTTNSSAQLEIERLREQLAQAESEKAAVIKSVDDLRGQVTDQHALRHANEQLQLEVSDLMENLASEEKTRRAMVAQVRRYETQMVEVNCQLEQSIRTEKQLMRVSEAHAALQDREKDLEHKVTKQKLQLKQLMMEVMERRQKQEVEQTELMELRRQVAVLTEKQQHARVDASVVASAAVQAQLQAQTQTQAQTQAQEEAARVNRIQRRFFRQLQVQQHQQKRKQLDLAQELRQLAALEVHEMQTRESERGPQHDERVRVLTPQTKPILRKERVELKRSASLPGAKEKQEPATGPTPGQRESLSASRLRQPTISSKERRAPSLVEPTVSTPTGRTPLWNNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX8</accession>
    <name>A0A8K1FEX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX8"/>
    <dbReference type="OrthoDB" id="164119at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40861">
        <property type="entry name" value="DUF2183 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40861:SF1">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="56597" checksum="5F62378A73D531E0" modified="2022-08-03" version="1">MKLIEALLLLFVLLFFVVWTILVWKGLNPLRLLRSTYKSPKHYLTPASLAERERLLKEANAPGPRTGNAMLYAESVARFAEDLSVQETEELIQFIHLNRLVNTDVKAQHFAQHCRQDVRLEDLPPATISLIIVCLQRYAKFDAVAECLKHCFEAKRGAECLALKTEVERHLCLYRLLYHYLQSSTARVAILKHFEREAEELKASPEFTAPVKLLCDIDDTMLSVLFDTRYPELTVYPGVHQFVHEINSSTSTEHEGSALNRLFRGPRIAFLTARPELLRRRSMRELRTCGFFHYSLLMGRLSNAVLGPERIAAGKLEGFSRYRRVFPEFRFIFVGDNGQGDIDLGKEMLRHPDLYGVSAVLIHDVVRNHERRPDIRSDTLAITPYRWNECIEHGIHSFRTYISAIFHLYTLSMVDAGAVMRVITKTTTAYSSITFDSEGQREKLAREIAADIVLVMGVLPEAQDDAFFAEMDSYLRQHVDTLIEHRADVTADIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFV3</accession>
    <name>A0A8K1FFV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_013511</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFV3"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="580"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1017" mass="112580" checksum="9D172050E39A2E2B" modified="2022-08-03" version="1">MDDMDQGPPRTPESEPEDMETQDTAASHDTVYADAPMDRAPPDTPPSSPLSIPQATNSTAFGATQRYLGRSTQDDAMDGRPRSPLSPTSPMSPTSAMSVSASAVSATEQPRYNFPEMSASIDATPMPRYLGRGGDQDEAEDDVEAELRRMAQRQLPRGDLGRLEWRLDSYGGGERGAPSSPSQQSIRSTRSDRSYSQYASNTENPSLPRPPASPPSSPRSRSSAASRAGRDDDDFSASRTPAPGGDDSEQQLNGAVVWGTNISVSESMMLFRLFLQQFRRPGQSILEEPYYIKVLRHMALTQSLVFNLDTQHLLQHRPARKIYNQLMLFPQVLIRILDMVVNEEFRRLSPDATEDEVQIQVRPFNLSDLSPMRNLNPSDIDQLVCLKGMVTRCSAIIPDLKEAFFRCSICHSTTQVELDRGRIEEPTFCVNCNTRHCMEMIHNRCAFTDKQMIKMQETPDAIPEGETPYTVMLFAFDDLVDDVRPGDKVEVTGIYRAVPMRASSRQRVVKSVFKTYIDVVHFRRVDELARRGTGDAEGVSGAANASVGDPSVTMDDPNRIHSTEEAKLVEFRRIASHPNVYQNLAHSLAPSIWELDDVKKGILCMLFGGTRKDKTTNAAVTNAANDGDTTGNHFKKATRSDMNVLLCGDPGTSKSQLLSYVHKLSPRSIYTSGKGSSAVGLTASIVRDMETGDLVLESGALVLSDEGVCCIDEFDKMSDSARSVLHEVMEQQTVSIAKAGIICSLNARASILASANPIESRYNPNKSVIENVNILPTLLSRFDLIYLILDKPLAETDRQLAKHIVSLYFDEDTRQARQQQGLNDNSPQLISMKLLTDYIAYAKKNIHPRLTRGARDALIRSYLELRRMGGSHAAKKNITATPRQLESLIRIAEALAKMKLCESVEESDVLEALRLMNVATQRAAMDPRTGTIDMDMINTGHSSLERESIAQLIEHMKTALSEAPNQALGVAELRKLLEETLKSEVKGNEFQMALRSMEDDELLQVSQGVVRYFGPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGP6</accession>
    <name>A0A8K1FGP6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">T-complex-associated testis-expressed protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGP6"/>
    <dbReference type="OrthoDB" id="341587at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF20">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="47938" checksum="DB96704C7EE10A35" modified="2022-08-03" version="1">MVSSSTTVGSTTDVSALSDQVKKYRSRVVGGYHNNDGLERSSAAVIPSLVILCLKVISDKFRLEPKIHNVPRKFLPEVMSRLPLDMDVCISAPNITDENYWKRCCMSKSAWKNLQISEHGLTWKQLFMEKNLQDMLEGFDSSTDDNDELIDVVKACQEYIFTLEIDQLLSHLDLNEVCSHLKNLTRLRLTYGVKQIGMKYERMLFGMKISDATNLSHIVKNTKTLTTLWLPNNLLDDDLLRMVMTGLVKNNTITSLDLSHNKITNHGARLLAKLLGPDSVITTLNLCDNQIHAEGGRYLSRGLKYNTSLTELNLRLNRLTDEGGRMLLEGLTEHPMLSVLNLSNNALGKETADALAEIIASSHCTLRSINLSGNSLTEADAETLLQGLQRNSMLVAVDLRQNEIPADAECLVRIAQKLRSNEVAPKAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH00</accession>
    <name>A0A8K1FH00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH00"/>
    <dbReference type="OrthoDB" id="100767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038127">
        <property type="entry name" value="FDP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451750" description="Serine protease" evidence="2">
        <location>
            <begin position="23"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="69487" checksum="F4A9022FD9F491E9" modified="2022-08-03" version="1">MTRCKPSYVWALSCLLLLGVQAKLQIQEDATNSQSRLRSLSLGMGCPEFLSSYYESNASDKQPFRSFTITKGSAYGYVAVHFSKLWLPKGASVILRGVEGYDRQDVTFNLTDAFRSGVKYEDVYAPPVLAKEFRIEFYRDQGPAKGKKIDFSDGGCHGFIVDWYHYVLVDSERNITPSREATCAQDNSEEAVCAYEQSSTRTSYLASQAVARLLIQKDVDKQAACTGWLLGSEGHLITNYHCVKNQDEASSTTVEFMADATKCSESCTEWGTCQGTVEAISTKLIQANEELDYALLLLQTDVDLPKKYGFLRLKTTQGHQGQEVYIPQHPMYYGKRISTLDDYGNHITIRDINATGCNSAGYSYNGDTQAGSSGSPVIDAQDHGVVALHHCGQSCANTGIPSVSIISDLKSNNVLPALAIDPGDNMNAEYFPDFHPREAVAAVNLTTWLKFDGAVHISSDGTSVGIDQFEFELREDAEIAIDVMSAEISDDGTYVDLNHDCQATYMDAIIFLFSKDNPKALLIKDDDNDNKGRSDGSVSARDPYLRTFLKNGTYVLAIASMPATSVDAYNGQSLVQDPPEIYSCVKSGKDGSYQIKFLGPEFLPPESMSFKRLPQSVTIPGTCDVPAEAICAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHC6</accession>
    <name>A0A8K1FHC6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHC6"/>
    <dbReference type="OrthoDB" id="77593at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="748" mass="82908" checksum="A008752DC536421B" modified="2022-08-03" version="1">MIIDLHTEKTEPPTTPSDAAEANDQAIKPVISLEVRTGEFDGQIAWGAPSPIETKAKATTKTSIEEQEAFIERMQATLDTMLARFEEQGLTSTAHEQQTIEELKQLIEEAAPMMTASLLQELPELYEQLVDAQTLAQDMLSQAEEDANGGLLTPSEAYLDIEDRIALEGPTQELVSALEQLAEEENDLFAHEKLAFIALFEPNATNARDFAQAFAHLRTASDAGLSAASGTLAMLSLIDFGRPRDPSASRESRHIHATELLRDLAKEQDFMASLVVANRIMTRQMDWYLRRYDRCHQAVAYYQRCAESNVNHMAEKGGEPHYVSVRLSEEFMTAGAFTTELYEDPAQRFEYYRSIAMNPGDELWAEATERLGEMYYFGDDAAGVQHDPVRAADHFRRAADEGGEPLAQANYGMMLANGIGVEQNNKTAMEYLQRAAAQGSGFAMNGIGVLYLTGAGVELNATRAVEYFEQAVEFGFLEAHTYLGSAYLKGTGVPKNETKAFEHFQIAASAGSHWAQFNLGVVYYRGSGVEYSCETALEYFRRVAVSPSLLTDMPFTMEKGHECYQKGDYLRAYLHYRLLSEFGSEEAQCNAAFLLERHGEVIYPSDDDGTLWMKEEEQDYRPMKEAFTLYKQAAQLNDTEAIRKVGSCYHEGWDGVCIVNHTRALEEYEMAATLGDAEAAYKCGAMYSTGDGVAQSLEDARKYFSMCSEADFPANAPCVIALAALSVISTVRNATQGILAPLWSSVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHU2</accession>
    <name>A0A8K1FHU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHU2"/>
    <dbReference type="OrthoDB" id="126651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="46728" checksum="2EA0464671DE5F4F" modified="2022-08-03" version="1">MKRQLLSTALPTLELTANEEQAVRDEAWAVIRQAVEMETAFYDHGTRVNPKEWKEVMAKDDLRIYRPRNLRVLRKNSGLERGVSTATSIAMPELFSVRSNDSSGSTRSWLSSFMRTTISHSSSASSEGSQAELADAPPLLCAGYVEGTLEDLSLGAYDGDDVTWKIRSAYMKDKFADARFLATIQRPTYENPFQFLGIKWFTTEYPPVVGAFIHIRDSLVVEAMGIGEDDKGEPFGYYMLHDYQNPRLPELSNFGIIRNKLSFCFISRQISPGRMRMYGRGCMSLGGSLPARLAIMISAISLTSTANLIETAYKKKLVWLVAQQEEERREIEEEQASNTTCHACDKTARLRGLIGCHACGFSFCPKCYVNRKLVVDASESHVTMRTLPFCFVCVLRAKQYPAIDVARATIILKQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI56</accession>
    <name>A0A8K1FI56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002392</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI56"/>
    <dbReference type="OrthoDB" id="5970161at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="539"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="816" mass="92861" checksum="E48D338324BB7D74" modified="2022-08-03" version="1">MAEFVEAILAQIIGNLSTALIIIIFYFNFLLFESYLRLIVWAILFSQALRQAKNSVIAVLQYLSNDPDVAKSGFLTCVFTKSCEIFLYNPYGTRRSAKEMFLNYGIFLFSLIGAVSVWLRMFSWASFFHTMFGFWLITLSLIKILDRRIFYYRYFFSDEVLVSSLLMLGFFSTGIFVIFYLGTETYMEGSRAAADVSNWIQKNFINDERTRELWSEQVENSRAMVSAALSGIEDNYNDTMWWPPVKGLVKTFYLDSKTGDGNTTAMTPFYSRLSLPENMTLVEAVTLAYSKVDSVNLTSVQLTDWTTKGLEVSSIAFGSVAQLIFLVFTLVIAFVSLGIRSFFFLSSMFYLLSTKWDPIERFVEDLLPIQVEKRPQVVHSLRKVVEGVFFLPLKMASLHALVTLVSFTMVNADFVYLATTFTFFISIVPIIPPYLVCLPWVFSIWVTSSFLKAIALFAVQYFAFTMLDDMLYEKSIVALNSYVSALSVVFGVYVFGIEGVIFGPLSVCAVTFAYEVSNHGIQAAQDEYFRASEDLRNFNQDDEDAEEPTSTGSSFDEEDEVPGTPPREARSPNTNIFSDAMYRVISGPLVDRVRRRLSMDISTDDSVCVTLLVDGLKTHRRVRFVVNKTWSQRMFYEHLRRTLRVHAVEGVTDTDDVEVLSPLHIMPNEVLKSTTHDKQHYLIKGLPVVNAELFERIFDHDWDHSDVERIVRDAVERKRIYRILKGAYRVIILFARFYAGKAALSGQPGTTTSDLHQVPSRLSILEDLNIQQVDPGKFGIVDTPIYRDGLVDFLLNVAKMVAANPNNPIRFQMLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIK0</accession>
    <name>A0A8K1FIK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_009652</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIK0"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="14">
        <location>
            <begin position="338"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="450"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW62159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="742" mass="82693" checksum="218713777F307FE5" modified="2022-08-03" version="1">MGNSPLTREFSTRRFSMEEREAMKKFCEEEIHLLRETFKGLANVKNGAAVDKETFLKCFPLPGLLGERLFEVIDKDGSGSIGYNEFVYGLAILFRGTRKEKLKFIFDLYDLSDTGSISRYELVTMLHQFPASTLEHLNLTEEPDTSTSEPSTKNINDEIEALVDLAFPTGHAHARLTFQQFTEWCDRTPGIANLLISVLPSEDGNAAPITPIDCSKSGLQGGDDTMRRRSSLKTLSPTRSYGRLITQGPVNQKELEKTRQLLLEAKQTCPVDALTGKILSLIGDVESALRAVVGASTTPHSSSSPSICLGPGSGVCASILQRGSIKLDGLDIKMITEQEFVSGDLWKRGSRLRQMIKRHYVLQGNFLYYYANKDDTAPRGVTFMCGCYVESLPQNAVVEKNIKYYAIDIVPEPTSSREKRTIYCKSLEEQAKWTKALRNATDKVSIEAFYVIGRQLGTGRFSRVCEATHKHTGATHAVKIIDKGKLSATERELLRTEIAILKLVTHPNIIRLHEIYEDKQNIYIVTELVSGGDLYSRIDGHNKYTESQARTVMLPLLESIAYIHRLGIVHRDIKPENVLCGDQGDLKIADFGLSKLVHPEEIMKMPCGTLNYVAPEVLAMLGYGKEADIWSVGVIMYLLVRGVLPFQSKTKNEIIQKTLHAEINLESDPVLSNVSPACKSLLKGLLTKDPSKRLTAQDALKHDWFTQRLVRGDSITGEMLANMHKTPRNSVTTLATTPTTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIN2</accession>
    <name>A0A8K1FIN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIN2"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="279"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="46254" checksum="FBE22A12E605B919" modified="2022-08-03" version="1">MEMTMETLRPTLLAAARAGDLTRVRALLYDPLLQPSMERMNATCRAHRETALATNQVPFVLDFRRLHVHDAWWTMYQPPMFWFRSVIDCGQLHVLSWFVSEEATELLGDTVRGILHQLCDAVMSASPEAKGLEAVEVLLSSYLFVHVLIGVERERVLMRLFRQALRSSGLTQTIDLLLAHGAPVTRTSRATSVTAQPMTAVQSLIANGGVDVEFGNVLADTAYGGNVDATRRLLDHGADTQYTGEQADALHVAVEEGKVGVTQLLLSEGMVDPNARDARGRTPLMMATIEKTSWNVGEKESDRLRIVQLLLDYGADVSPTDESGNTALHYATVGEHLDVVALLLSSGADPNVQNVYGDTALLDFASRIAVTERHYVLFDMLLAGGTDPFLQNAKNESFVSLLSSVSLAGLNYINERVQHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ29</accession>
    <name>A0A8K1FJ29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ29"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="44580" checksum="EF01FCC4D549EED1" modified="2022-08-03" version="1">MAVEDYGEVTPLTEHEDWMDISPRSLLDIYALEWDADVVEALQYDEKAGNESQTQANGKDEDVESEASEASTRRKTSSQDKSDSQSPRPKRRRVNRLREELKDLRKVVEGLEMHLRLLKLGRDQSNGSVQAEATTSTQLIQPRAMWKAVALRQHDRRRESELENSRLRMLLDEQMRIAQGLERLIQRSVTSMLNPRYPTPLALNTSPADYAALARATNDLYLLVDQAMNERRFEDLESELREISVHEDSIEMLGGRIAPLSCDLLTGGIWQSFVEPSRLNPSYQAQCVVDIPDYNCSTFTLKLDTVGRRGIFRGNVALRRFQEKSRCVFTIVSYLTRVEPAEVSGLVFRSHGIVERQQGLVNSSLPTFVVPEQYGMTELAKSLMELTANWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ95</accession>
    <name>A0A8K1FJ95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ95"/>
    <dbReference type="OrthoDB" id="5835702at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03754">
        <property type="entry name" value="proteasome_alpha_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000036">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034642">
        <property type="entry name" value="Proteasome_subunit_alpha6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="26905" checksum="58C3806C3E7D9B8B" modified="2022-08-03" version="1">MPGDGYDRHITIFSPEGRLYQIEYAFAAAKECGLTSVGVRGKDSVVFVTQKKVQDKLIDPDSVTSVFQITPQIGAMVTGLPADARAQVQRLRYEAHEFENKFGYKIPVHVLSKRIADVAQVYTQHASMRAFGVITFLIGVDDEKGPQLFKIDPAGHFWGYKATSAGPKEQEAQNYLEKKIKANPTMDNETTLHTAITCLQSVLSADFRPNEIEVGVAVTGQRFRKLTEDEIEAHLTAISERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL2</accession>
    <name>A0A8K1FJL2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosidase 2 subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003945</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJL2"/>
    <dbReference type="OrthoDB" id="28322at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029147">
        <property type="entry name" value="CFAP77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039794">
        <property type="entry name" value="Gtb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036607">
        <property type="entry name" value="PRKCSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028146">
        <property type="entry name" value="PRKCSH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630:SF1">
        <property type="entry name" value="GLUCOSIDASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630">
        <property type="entry name" value="N-LINKED OLIGOSACCHARIDE PROCESSING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14825">
        <property type="entry name" value="CFAP77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12999">
        <property type="entry name" value="PRKCSH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13015">
        <property type="entry name" value="PRKCSH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="7">
        <location>
            <begin position="660"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="774" mass="86617" checksum="E3E83D48C306C00E" modified="2022-08-03" version="1">MSADLPPHMLRRTMIKPTVGHVRRSSYDLPDARNPSHVYGLELPRDPENAGQVIGRWVHATPSPAAKCERSFIETNKQAIESGYITAGDARRYATEHPDILVKTPVKRKAGYTPTRDAVYGIRSKASEDITALVQARFTNFATENDDYPDLTSMKIKGKLPLPRETKTSTLKDVRVNPKPAERHHSELFKMSKFKNVGSMLSGELTVRGVAPADLEQYQRSGGLLCRIGDREELLPHDRVNDDYCDCDDGKDEPGTSACSNLAESTFYCVNGGFFSKQIPTSLLNDGICDCCDGSDEFDAAAGAASCSDTCPEEAFVYRQRAADHLGLVQRGYKKRQDVLRSTVSDYFSQGEDKKAATDKTLASLVLLKERVELHKAREERREKKMRLEVARQRQAEEGATEDAAVECKPGAENGDECENPGAKDDTAAESFDEVDTADVADASAASEDDTDSRRVSTMIQLSDGTRVSLAEYFRMEHAKPTKKKGSRSAEDMRRNDFLGPLFNGDEEGRKRIGIYTLRGIGLICSPVRLVIEAVLFFPRFFWDLFSASELVSPHLERLPSIPSITHSPTFRRLAGGSVNEAYKSTIWAGRVVWDAPIVAYNYLFPAVDPELTLPEAESLRKALREIEDDIAKLQKRRETQEADLKFDFGPDHAYYALKDQCIEKKVEKYDYKFCAFKDVRQDQLSLGNWEGYGKSTEDTTDHNVMRFTRGRKCWNGPERSANVQLVCGETNELVSVDEPSTCVYDIVVQTYLACTLAELESAQKEFAFWLQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKN1</accession>
    <name>A0A8K1FKN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKN1"/>
    <dbReference type="OrthoDB" id="59472at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="367" mass="40361" checksum="71019CFD35E992DC" modified="2022-08-03" version="1">MDAHEDSSKQQQLEQALTPVVAGSTLGRYEQWVLKNTSVARNLETMLYIAPQFVPKNLVDAEVASQSGYAVVGLLGLFHDYVLYKAAHADAKPSTSFTRMVRVPLSLVSHVQVLSEVIARKVGGEVSRWRVIVLIELFKCVCKLLLLTQERRALLVGVGKYKSIHPPGTKKSPFARFSKSNKQRGSRTGKIFANKNATADAAPAEPTPEDKPAGPTAITFADPTVSVPDVANEKKLLAGEILHVFRPLVYAVLRQRRDENSWLPALVALAIEVSGLVLSSTSLENSKLVTPTTLPQNKKAQEELSARKMQLLLYLLRDPAYVNLTKPVATTVCGVTDYVPVLGKVFRLVSIGLMDYYARFHFYTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKQ3</accession>
    <name>A0A8K1FKQ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKQ3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475326" evidence="2">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="33244" checksum="4B7C2DF06A6F066D" modified="2022-08-03" version="1">MIMAVSMFMIVAMIVSMATGDRVRQQVQERVTQQTASSKAQKHTQKGLLCFLVADTKRNKEQDDNWCGTNKRRREESFSPDLGVKSVNLGRRWLGPMIVRVSMRMDMIVVIMVMMVSMAMVVIVVVIMLIMVVVMVVVMVVLMVMVLVVMVMIMVMVVMVMIMVMVVMVIMVMVLVSLDITAGFLSLFVVMMVLVNVMMMPMVLVGVHRRVRHHPHPHERAILQTTPCARGHGHRQRHNRPTELHVDELFLRNDPPDLLTRGHYYNLQDSAPTAEDYQEVMPKVSACGRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKY9</accession>
    <name>A0A8K1FKY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKY9"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="109"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="576" mass="62979" checksum="F50E5AB7755FB7C2" modified="2022-08-03" version="1">MKEAATRPTIPSPSRPVASLEKASGSKLQSPRIKRQHRIHLRPAVDGDTFISAEDDDDDDGQNASLSCSDGIQSSLRSPTPAESSSCSSAASPSTKSETNDPIKRTRPYIRKEKIGQGAQGSVYRCLEVATGREVAAKVIMTYELSSAELEAIKREVKTIKQLQHRHLVQYYRATEKKSKELIIYMEYVSGGSLSAKLRQDGALALPRVKQFTRQLCEALQYLHQRRLAHRDIKCANVFLDASGEEIKLGDFGNFKEIGSVSLVGGLKGTPHWMAPEVIREQQTSEDGWFKADIWSLGCAVIEMLTGHSPWQQYSNPLTAMYQIVSSNNIPTIPADATDETASFLKLCLQRNPDDRATTSQLLAHEFLHVVDVKRKDSEANIPAQASESSDLQPKSGASPQRGESHIRKIPSPSTRTTPARPNHPALGAPSPGHRQKQLSPEMDDASCDAIKSPAQRPRKVSQIPRLMPLELIKTPSNQDHELHPSPPPSRLASNSLGKPQVTGMSIARGVSAGKLPHSHKGSLSPGVLIAPVRLRRISTAPHPSRDPEDIMSSASHQLKPKLPPLSARTHAETSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLN7</accession>
    <name>A0A8K1FLN7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLN7"/>
    <dbReference type="OrthoDB" id="127272at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="43533" checksum="A5CEE0C9C9F47FAB" modified="2022-08-03" version="1">MGRSDGWHDRPRKWEPTSSDDLLKKRYTEMDRYRLDLNQQRFAHMGREERIQKFGSHIIPIHVPLDRGETIEAYEQRFVHWLAVRENVRLQDIRDPMAERSYRIQFANKNANESLDYKFQYRNWVPPTPPPSYRLEATESSTMRSSSDQRPRLKRLRGLESHEIQRSSTSVDTVSSDIFDPVEKRLHGEYDELNERVLMNNRVLEMSVKRLHQGSVDNIKEATAQQEEIQELRALIRQEMDNRDAALAMVIVYLWRKEIGDLEERIKSKDIANVPQVATKSHQHCAKIASDLVAKREELAKVKKQLDEQLEKRSSPPDSAHLSMAKELGEKIASLEHEIDQLISTRRQEFQTVLQCDEHVRHLIRTVLAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLU1</accession>
    <name>A0A8K1FLU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLU1"/>
    <dbReference type="OrthoDB" id="160817at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477779" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="36638" checksum="E78400179964ABF6" modified="2022-08-03" version="1">MRWPVAALPIVCWVLLFSLLSHVTHASASRLSIVHAFSTDEEATMMSTVLARAGAILDADTDLGVLTTPTPSSNATNNRNETEDNAAAAGLLKIYSLGGDSRVLYKKKEWQVVREATSNGTVWVRLKGNGTQSFACVLVVDASEAIPIESDAGGRAIVSILQRMDSFCGKQDLVLIGFTATLSTTQVKYLEGQAPINASSVPRVMVESVVLGYDKPEFADAAPSSATDRFFLHSAQTACLVDATAVSADTSTAIDLAMCFGTECQVCHAGSSHVPDPLGDVQVDEEEESSSNHKSLVIVASCGAFLLGCALLFFCFNVKQCLSAHDSTKPEKELTSHLAYVLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM78</accession>
    <name>A0A8K1FM78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM78"/>
    <dbReference type="OrthoDB" id="67317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11104" checksum="F9B37A7D386DC329" modified="2022-08-03" version="1">MVSKTGCALCCSLLSCFGFVFLLAIGILVKTQPEYMKLSKDVKGTGPLFGSAFLYGTLFVASTTYYYIENKKNDASLARYEAQSTAAERKPLLQNIPEDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMN4</accession>
    <name>A0A8K1FMN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMN4"/>
    <dbReference type="OrthoDB" id="264795at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="3">
        <location>
            <begin position="49"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="491"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1239" mass="141076" checksum="4CC45BB971E59DF3" modified="2022-08-03" version="1">MFSAGGFGGVQHSNPFGTPVQASPVNPFQGGRGNASGGSNGVHTSFGGERELHIRVDELSLFEKNFPGQPGMERELIVKRFQRSSADHKLDIPSEVRPPGVLRSTQLYLEQNIMDREKIGEDPRFNPPRLPEMIELYNFCWDRCRMIRKDFVLQNYRGAGGRVHPIVLDVHERIARYHILSEHELCEVPSFVAQQNMEQLGQTLKSLNELYDESRKIGDLAYLSPFEAEFRAYFILCTLDNGRGLDVLKFVKGLTPQIREAPQVKFAMKAFVARHTQDYYQFFYLLREATYLQSCLLFRYIPSMRSQALERMNRAYRKQPYPLEDLVDQLCFDDLDHAESVCTHHGLDIGQDENDGAILVNFGGDFETDIDLRKNKNPLPIRSSHVYVGQKQADCWRKDICRGVTEYTPEEYPALSKLVEDTEDLERARLYPDRPPYEDEYSMFSVYTADPYDSNRQAGDQNGNRTPASIRHPEGEPTDQRHDLDDIAKRKAELEHTKQMMLQRLQQLEREKEAKTLQVQQKALESQREAELEARAKAKAEEDALERQREQEAAALREQLLAEQREKQLAEEKRRKEEAKIVAEKAKADEQRRIAEQLRQAEEERVRREAALRAEEARRIAAEAAERRRQEELAAAEAKRKREAALEAQRQAQLARELELKKRAQRIQKQKLAILKLKFHQWRAYVAKSKEALAGVKVGTTQIISGNSARPQNVVEWLFGGRRAAADRIGLRRRQWLSTDTSSRWISSRQWDPLNVVDIVEPSLFRANRASTGWKLLIADLLDEGISSFGSWSALKLGVSGASFDEDDRASTVHYVQLSDSSIPLCLRYLDASFTHSLSRLGQQKKLAGTSSILLPVDLSHVSTPGIFQRWEERVDSVFRNLHASSRVSLMVLAFCSADLHNKLMALTTVEEAIRKLQTRYAAHVNFVDGELVLEDDLGSADVVEAKVTNILVRLADHSTKSKTMCVTIGFADLLEIAVQNAFKRSMGGNVAEIQKQLHQQLSSLQDSLTSPEVLNVDIPIPELQDMVKLPAYGWNSSEAQAKRTRVLVAAMTLQLATDSTELRNDRVCEMYFHKIVEFIDKLFAVTRGSKSHISSDELKRNIYGLLLPIHEQVVAGDGGSVHERIPWQRILEKVFGAFVEEVDNMALYVPKDLPVFQEHNQEEPKHVQTSTTQGKKALDPNAVAAALAFARSALKRTSTRHELDPEQKVGLKKLRQSIAQDRAAAQQFQYFLRRELHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMR1</accession>
    <name>A0A8K1FMR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMR1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="59936" checksum="5A1B6D39086BC82A" modified="2022-08-03" version="1">MGSLLSTLPSTYELIIASVCLFVTLGLSVPLRALQRKLRIAQGLAPIPGSKGTFLLGNMPELMRHQHRIYDYLEESLKACGGRMKTPWHLFYDGSLYITDPVDVEHVLATNFNNYIKPQGFIDAFREVFEHSFFALSHAHTPDNGAKWRLQRKVASKVFTTTNFKYFTEQVFTKYARAIAERLESEGSCDMQEVSAEYTLTSIFDIAFGTELSRFMDPERFAARMNFVNEHCASRIFIKQYYKWFRWVMPSEYRVQQYTAEIRAIADQILLERLTEPAEKLKARSDILSLFIKKARELDDESAELLSPETLRAIILTFLFAGRDTTAECITYMFYALARHPETQQKILDELEAASASMPGQGTETLSYDLVKQLKYLDAVAYETVRLYPSLPYNVRHAVHDDHLPDGTFVPAGVDVVYSPWYMGRNEAFWGKDALDFRPERWLERKTRPTAFEFPAFHGGPRVCLGMNMALLEAKIFTLVLLRNFHVQITDGEPKERGYVLKSGLFMDGGLPLTLRPRARAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMY1</accession>
    <name>A0A8K1FMY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMY1"/>
    <dbReference type="OrthoDB" id="58713at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="647"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="690" mass="78282" checksum="9C7C92B4D26EE9A7" modified="2022-08-03" version="1">MAVMATKAELEQLWTLACLLSNQQLPHQALPCLEVCVAAGETSQPPTAFVIRAHVLLAETCLTLCRLESKEQSRELWWKRYKRAETSIYVVEKALESKTHPPKVEQEWVVRLYQSKVLLVQQTSKIEQPVQNRQVLENVCAAIRACGEDPPAASPLARLKEQLCAQLRATLADMHLQSMLRSSNQDFEGLAAFDDNLRVVRTAVPSHIDPDFQLWLVMVSCHVLVTSLRHRAPTEVTKAIGFADQWIASQPNLGPDLQLYHMIAKCLSFLRSGEFKKLGPVVEQIKAFRASVEIPTDSPSYVQAAFVDNIIDGLELEVISRYDPSQAMGLSMKAIHLVQTNLVKYESQPDIHLLLLGTLFDMLYIHCNLHLQHSRYFEMAVSVVQMLKLFNAYNHHLEPTIFHVQYSVQIHVLVAKYAIAIGRFKEGESHLNYIVQHLLPPISEDGRAYPRAFIHLWIDLLEASSYCSGVADPMFSIRSNDANGIQMRRIFPSTMQLTFLGKILENHGLKELVYKDGNVELRAKYDLAVCMWLWATQELGLFAATLQNLPRGHKIFPIHEKLEESRPDMLRMLHESLQLVSTHVDCAETTAEIMALFGPKLIEAGRIENGEETLKSAIRLSLHAKNALLQTRLLVDIFHLYTHRQLVQAQATTAEKYEKKIAALQRRIAQAQSENATNERIFKWTDVKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPE0</accession>
    <name>A0A8K1FPE0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPE0"/>
    <dbReference type="OrthoDB" id="1938039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="120" mass="14019" checksum="48D3879C4A1C1DAC" modified="2022-08-03" version="1">MDDLYGDLDTSTQALAKTELQQEKQRVEKENDKLKTELAELQLQNRLLGERTKALETNISTLFVTAQHELKRKDAEIQRLREALTKAERRDSARSDHQSHRRYHESRGDSPSRRSGHSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQB9</accession>
    <name>A0A8K1FQB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQB9"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="10">
        <location>
            <begin position="74"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="224" mass="23858" checksum="3E9B4DFDBAEC534B" modified="2022-08-03" version="1">MFARAARRAATVAKRNATRALHTTQVAAATKKAPVLAAAAAVATASVAFAVASSETNAAQAQKVPHAGVPGTKHERTFIAIKPDGVQRGLISEVIARFEKKGYKLVALKLMTASEQRAKAHYADLSARPFFPGLVKYFTSGPIVCMVWEGTDVILTGRKILGATNPNDAAPGTLRGDNCISTGRNLVHGSDGPDSAKHEISMWFTAEEINNYERALDSWIVSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTJ3</accession>
    <name>A0A8K1FTJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTJ3"/>
    <dbReference type="OrthoDB" id="161460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434368" description="Chitin-binding type-4 domain-containing protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="187"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="25077" checksum="64DEA24D630F2477" modified="2022-08-03" version="1">MKLATALLTAAVVAPALFLTPGVQAHGGMVEPESRAIRTMKLAIDSTFGHPIPMRASYTNGKGGNCVDFTPDTNLQAIPFGESKIKMRANDGANHIGMCTAYLINPKDKNSKIKVGEMKDCMRSLHPGPGNKGDQPIPAEMTINIPQDQKVCGAEHCVLQFNWDAAHLAPTIENYNNCADVKLMGGAPAPAASSTAPAASSAAPAPSSQAPSTTPAPVSSSKAPVSTPTPSQDKCRVRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C217</accession>
    <name>A0A8K1C217_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014767</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C217"/>
    <dbReference type="OrthoDB" id="118256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469204" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="11">
        <location>
            <begin position="210"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="10">
        <location>
            <begin position="263"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="87"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW54996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="502" mass="51876" checksum="105619BD8F2C5F19" modified="2022-08-03" version="1">MVKASVSVIVAALGVVSLLAAPVAAVPVDSDADMDSNPLGFVVAAAPTGGFEYSGPARPDSAALTVWCNQNCPAFCPGDMCRPVGGAPAPAPAPAPAPQPAPAPAPAPAPKPAPQPAPAPAPAPQPAPQPAPQPAPAPAPAPKPVPAPAPKPSEAPKPAPGPAPAPAPAPKPSEAPKPAPTPAPAPAPKPVPASKIKGTYSYKGKFAGNVPGSYERVTDLVGCKKTKVHINNPIGPMSEGVSVIFRGPMNIHDIAVYQPKNNKWTRVSSFSQASGNTDNLVFMNNKNIDYSGQNKHGPQGYATADGASKADKPEKFSGKLAEAKEPAKIGGGPGLSTGAEVNIMTAEKCNGKCPGYHGENDHKGWYGGKKIFVTKVHMPQGGSPNQPAIWMLNDQVMHSGQYGCNCRGMGAPGGCGELDFAEVIETNPARDRVSAHYYFYDGTLNAPNGDNWAPRPTNGPTVYALVMDDSGEGLIKILEMEDFDFGMTTISQELYDQWIKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2I1</accession>
    <name>A0A8K1C2I1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2I1"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="5">
        <location>
            <begin position="326"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="56106" checksum="B62C9F4148EA509A" modified="2022-08-03" version="1">MTAESRTDVSCDGSVTPKDQNALVVVLSVNDVYDMYPDQQGRGGMAEFATLLERERAKIPAHAKLLVTLNGDFLSGSQVAERHKGAHMIELLNHLGIEYVVLGNHEFDFGDVVLRERMAESRSKWFGSNVIETATGKLFPGVIDTEIVELTDGLKLGVFGVCTQETPNLSYPGDNIVFDDVFATSKRCVRELQDQGADFIIALTHLSIAQDKLLARKVPGIDVMLGGHDHEPFTLYEGKTLVHKSGQNAFWLARMEFHLSKSGLQPERPLAITPQWTMIANQNIPPQASTQEIVAKYMKALADAEDEADAKRVLATLALPLSTKTSQLRAGECNMGNLVADAIRSELSADFGLMNGGFIRGDTSYEARTVMTMGMLNQEMPFPRIGVVVRIKINHFRDAIVQHFSKYPQLSGSYPHISGLRVTIDRRTNPSEPTITEMVDASGTPLDMEAEVNVATSDFTARGSEGCTAWKQGKIIHTGERIAAIVSEFLLKKRLIAYLEREGRITILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3M6</accession>
    <name>A0A8K1C3M6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3M6"/>
    <dbReference type="OrthoDB" id="333551at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025066">
        <property type="entry name" value="CCDC174-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="36007" checksum="7BF1CC0F595E1AC7" modified="2022-08-03" version="1">MSLGFLTESALLPSKAKEIKVDSKSLLDLKAVVYKKEQERRERQRRLKEALHQEEEEAPGRGKYARLKAKKRKGSDEDRLGGTANRGVDKRRKRDESEKELDVDDDADDAALQRKSREMLEKKARLYEAMMQGKTMEDREGNGMSAAAMAESLVDFDEKKRSGMAMKESALWSRSKNDMVEIADEFGRSRLVEKGSKEYEEYMRTQQTPPRINQLDENRGHDDQPAGGSFVASQWEKTLHSTEKAYLQQVHEGVEQAKRSTVAMDKQTRKQLRLQKLRQQQQQQNVALQPDNSSTENAAAAAQATEFLNQFTSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4K0</accession>
    <name>A0A8K1C4K0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Centrosomal protein 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">FGFR1OP N-terminal-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">LisH domain-containing protein FOPNL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_006331</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Microtubule organizing center</location>
            <location evidence="3">Centrosome</location>
            <location evidence="3">Centriolar satellite</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasmic granule</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CEP43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4K0"/>
    <dbReference type="OrthoDB" id="5970631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034453">
        <property type="term" value="P:microtubule anchoring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.40:FF:000002">
        <property type="entry name" value="LisH domain-containing protein FOPNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018993">
        <property type="entry name" value="FOP_dimerisation-dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15431">
        <property type="entry name" value="FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15431:SF4">
        <property type="entry name" value="PROTEIN TONNEAU 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09398">
        <property type="entry name" value="FOP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGFR1 oncogene partner (FOP) N-terminal dimerisation" evidence="14">
        <location>
            <begin position="59"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="133"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00055043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00076755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW56321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20193" checksum="7BC63E52600B9A19" modified="2022-08-03" version="1">MGSFVEGTAKMESLADLKGVLKETLEARGSLGQIKARIRAEIFAALDDEGVPKPKLSNENLIINELIREYLEYNGYRHTQSVFLAESGQPAEPPFHRQFVAKELRVEEDPRYSHVPLLYGIVSSLQQARVEAAPLAQEDEQYDRKPGQQGETSPSLPSNKSTKDRNDGLRASQPSPVFIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4M8</accession>
    <name>A0A8K1C4M8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-adaptin appendage C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4M8"/>
    <dbReference type="OrthoDB" id="69705at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="2">
        <location>
            <begin position="423"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="60940" checksum="42DCCA16696E6C49" modified="2022-08-03" version="1">MALSLRSSIGPLMCADVAFQMQFPRQEAMPLEELSELTTGKNCGKSTVLAQILREIEKTVSVRGTFAAVDCVGTRMDEEMIGLFTVLQFCSPEANKDKGEMHVKEELEQLFEGPDRQKLYTSLIYRDVMANVDNVMISKSYELIKPEEDTPVFKFRAAQMWTEADQINVKLKVRNDGSSPLHVFAVTVKAFEDSSSLGVMLLPSESVAVLEPSQERTVAFQLKLAHAVDLPKDRHYGLYFAHSALRAHLLEGKLDGTKLKLVDKKKTQLKTVSDSISFKVDESASLEGSYSAFPFSMWRVMSIGVVLCVGLFATMFIRRKRIRFEWIRSMDCLKTRPLKYKTSNAKMTEMTVKKPSYDPVEDALDLADLETLESDGLLSDDMDDEPIVKPPTAKREKMPAITMQWRKPALPRDRPTIRRVLALDNTQRLNPKRFENMWEEYVQRHNASFRAAHRPASSAFLASMEAVGIVCMASGTVNGVEKYVLYAKQKDTTDYFFVSIDILVATNETNLSIRTGTDTNESLIQQFVALVDAQLDKLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4V2</accession>
    <name>A0A8K1C4V2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008805</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4V2"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000088">
        <property type="entry name" value="Potassium/sodium efflux P-type ATPase, fungal-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000160">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF20">
        <property type="entry name" value="P-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="812"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="885"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1030"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1058"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="60"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1125" mass="122509" checksum="7EDF6316FD30C6D0" modified="2022-08-03" version="1">MSPRALDTEYVEMTVEETKPNTLEEDHRSRFLSDAERLLAEHPDEVRQSLVSLDVTDQKHWDTKPIDVVAKLLTTNLERGLASIESEQRLEKYGPNALDEDPNAPLYIVFLLQFYNLIIMILLVAAALSFALGKYVEATAILIIVTLNAIVATAQENNATNALEALAQMASPLCAVIRDGEQQVVESKLLVPGDLVLLVTGDVVPADIRLIESTDLKVNEMLLTGESEDVAKKHNATASKKLTADNMVFSSTTVTAGNARGLVVETGMTTRVGSIAKLLKGSSGDDEKKKRSLNPLASCLEKYQPKQTPLQLALHKLGFLMGSIAMTVCLLVFIVGLARGSKDIKNPDRPVWLAMLMVAVSLAVSAVPEGLPMVVTICLSVGTASMVRKQVLVRKLAAVETLGAASVICTDKTGTLTEGKMTAVKMWGDFKTYDITGKGFNPEGGIFFNGVNQAVPGSPNKQVSSTLLASVLCSNTQLKQQEVDGVMTWVPFGNSSEAPLVVAAAKAGIWEDDVSMDYKRVVEVPFSSSRKMMVTVNTLPAGGMFGSLALGDKTQYVSCVKGAPNYILKNCTRYCQTDGTFAPLTDEQSAQVMEAVDELSSNALRVLAIAIQPLGDLPYAPECEDIDEKFAALSQPLVLLGLMASIDPERDGVREAIATARRASMRTIMITGDYLKTAIAIAKNIELLEVGADVDSEATDCTQLRPHGHEYLPDHEIDEITSRAVVFARAKPEDKIEIVKSLQRQGLVAAMTGDGVNDAPALKEADIGVAMGISGTEVSKGASDMILLDDNFVSIVAAVEQGRVIYANIQKFVIFLLSTNIGEIILIFSTIAAGMPLPLEPLQILILNLFSDGMPGAALSMEKGDPTIMEHRPRPKKQQLIHGRLWKLVGFNAVFIAAGAIAVFVLGVYWNFGHVLLDDIVATGAGANGKDYTGVTCNRWQGVDKGWKVYGNCEAKFSNGSYVFPDIPNRDEYETDEMYCRGGEYACLWDGMARSQTMTFICITYTEVFRAFTVRSFTESMFIGMFSNKHLVVAVTSSVLLTIFVTSTPVIMTDIFGFAYISWFQWMVSVAGALNAAFWAEVMKWLARRRDREAARWDAMRGGFDSVLTEIRHLRLHIEKLEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C512</accession>
    <name>A0A8K1C512_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C512"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="905" mass="100670" checksum="14DE4E4D3034E1C4" modified="2022-08-03" version="1">MMRPTALRQLQRATASAAVGNRALLVHADPFSGAYGAASWFSTSQKKQQRNGRSAAGVHINDIPLTDLATLPKNKVMQRHGRGKYMRMVKTLPEQLQQLVTDSKPSRDVLKHVFYAADKCNAPDVMLNALRALEAQQIEKVSGSKPRSIDFAVYTVLYNALLRSNLRDRMLAVYEDARTTLPRPLPEVVYRFGIVGKFGADDLDGVLGIVEEMQGDQVAITNEMGSQLMLGFAKANETDQAMRFFQIILEGDVTKLHEQDMNRIILAFGCIGDLHGAFEFYRQCQLPLSTTVFNALLSVCVHNDAPKEAHAIMKNRVRFGLTLDSVGYMRVLEALELFDRHDQIVHILNEMRQQDIPFAPKVNEIVQRNQEYLLGTAFAIRPVESTEHPSGVLELLRDSITTKDTGHAASLADLLVSTVRSSDVNLNMAEASVIKRLIWLGATVVESSEAADLVVQAFLDSNQQHKLQSLVRGFQLVKGDFDAALNRLFEFYSEKNIPEMVDGILSAMLHQDARIEKLDDAFTIFADRDNLDAVQRLLTQSFKRYNEALERHNGDISAASQELPFSVHGILDNALDCIVRASAFDQIISVLDNAESHGVKLGQEQYVRIVAAMKTRNRKDLEGADAQDQQSDANETYCAEHVASLWQDAMRRNIPIQKALIAASSPLLAAGNSTQRRLLWDAYVRICEMDSTADDYALQTVVHEHLMEVAVKDLTSTEAVAVYEAAAEPLAQANQGVPASLTVALIEKLVSEEQIESAIARMLGMRKPPPGALAVTLRAAAERDPSDPRVVELLDLQLQQKRGLGFALATSMITAAERSQARELAWRVVEAYEYRKVKPDMGQKGWKALVKNLTGLREHKLFYEGAMRVLLDDEDANDKREILDERLGGLNELESELVRKLEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5H7</accession>
    <name>A0A8K1C5H7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5H7"/>
    <dbReference type="OrthoDB" id="5586934at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802:SF2">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802">
        <property type="entry name" value="SI:CH211-161H7.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="32152" checksum="0A64F1FF5B478DED" modified="2022-08-03" version="1">MATMMMAMPSSRLAAFNAALYVTQLVITGISFSRPQNEAQYDTLITPAAYAFSIWSVIYVLTLSTVVTDLFFPAFSIYNNAAKPDFLRACFALSCIFNFGWVVLFHGDLVNLATVDITLLWLSLLPIYLFVNFERDERPFSWRPYVFSELSIRLYFSWVSAATLISWTITLQGITGGFLSLSTYLMLLSVLIVIATVGVVYGRDSVIGLVAVWALNALAHKDLGKLDVDDSEKLLRIQAAATLAASVTLTLILVSALERIVFRVRSSREWRAYLKISSETEAHPYYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5R7</accession>
    <name>A0A8K1C5R7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_002962</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000738">
        <property type="entry name" value="Dynein heavy chain axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001275">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001298">
        <property type="entry name" value="Filamin/ABP280_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00557">
        <property type="entry name" value="IG_FLMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="9 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Filamin" evidence="14">
        <location>
            <begin position="453"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1363"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1982"/>
            <end position="2134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2849"/>
            <end position="2897"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3242"/>
            <end position="3269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="4205" mass="471407" checksum="06FAFD21686D8C29" modified="2022-08-03" version="1">[encoded data, 4205 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C711</accession>
    <name>A0A8K1C711_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C711"/>
    <dbReference type="OrthoDB" id="29596at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="826" mass="92287" checksum="BCC53A49956EF40A" modified="2022-08-03" version="1">MARKRQREEAQALERTENVPPALEMEQDDELMCMAILYDRGQLGAAIYDAVTARLKTIQLPVPNLVELGEVVGRMLTQFEVHRVLVSSRNASTHGLLQVLKSIEAKQSRSIGISVRKHAEFNYLKACNAIERIRMGDTWWNESLANQGLTRREAYKYLGRYFDFESTELIRATGALFGYLATEKIGAQLDGAAVICLTSVERVALDGIMYIDAGSMKSLQIFSNEAHPSLVKGYGRSKEGFSLYGLLNRTLTKGGAALLRQWMLAPLLDVAIINMRLDAVEYLCKPDVDELRKAIRARLKCFGDVSGIFNRIRSRCASVSEWNKVSESIGSYLALQNLLQEHEASQSSSMPPLLCDILGERSMIHVSNLLGNIIDFEESAQEEHIVIRAGVSDVLDAARAKYEDLDNVLTEVAYQIQESQPSLSSITVQYIPQVGYVICCEAATALPDFVFQFQEDDTTFYYKDSCCRDLDATIGDIFGFILDLQRDLLEELTVALLQYEHCIFEMAGIVSKLDCISALADVAKNFNYRRPTVTEENEFMINTARHPLQELIVDQYIPNDTKLSDDRVVMVVTGQNGSGKSVYLKMVGLLQYMAQIGSYVPAHEAQIGIVRKMFTRIHSMETASISQSSFTIDCNQIVRMLQHGQERSLFLIDEFGKGTAEADGTALLAATINYLVAKPPTERDPRVIITTHLLDIFRRGLVQTDRAESRVICTMMASASASSEHSPVPMFTPLHELRQGVSLASNALGCAINCGVPPDIVKRAADVLEMTKKCQPITRPPTSSQEDEWERQVLELFASVDNWITAPADKLTKLQTMIRMSDKWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C728</accession>
    <name>A0A8K1C728_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein OSCP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C728"/>
    <dbReference type="OrthoDB" id="2157380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019332">
        <property type="entry name" value="OSCP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21439">
        <property type="entry name" value="OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21439:SF0">
        <property type="entry name" value="PROTEIN OSCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10188">
        <property type="entry name" value="Oscp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="43171" checksum="6F71950774220E7B" modified="2022-08-03" version="1">MAGSLMTMPMLIINMGAEMIYVLDQRLKAQNIPRDKSTKVLEDIVKTMHNDKFMLELFKPHHMYSNVSTRQIFDRLAHSSIMRLNTNSMDKLYDLMRMGFKYQILSCSSADELLQVTMNHLETTKGLVDSESVKRLIDETILLTSQAFGTMSSADFYLMKQYLCRFFQDTRIKVSLFLQNGMQGMDGTLALRYDGLTATGGKVPGTIRYYDNDGTVDDEEKFAIASADDSIEAPETPVIEREQRNTHLGYNMYEADAKGAAAGKSTKDLVADAKRAGAKSVLDRKPQKLFKATASDGLNLLADLLGASSKEVEDKGFKFNMFPDDSLRAKGGGDDDDDEKDVPTIWIDATSDRKETDAVVHDFGDDGGKRGDKDEEDDLLQLMDSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C798</accession>
    <name>A0A8K1C798_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C798"/>
    <dbReference type="OrthoDB" id="163128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000009">
        <property type="entry name" value="Probable E3 ubiquitin-protein ligase HECTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="255"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="597" mass="68525" checksum="2EDAB08E0161B73C" modified="2022-08-03" version="1">MEQKYQFLLITIGMTFGLILLLLFIRRVHNSDYDKMELNQPFIAASESREEAAWREAQEGFEKCEACGFTNFKRIVTCSVCHAPLGDEKTKAKYAKKNKNNANKDGSVRAQRAIKRKEWSRKLDVEGKLYWFRDAINTSLDKLLPGFTFSFVANEAPATANVTKTLHMETEGMQVEYLDVAKASPLAFAVGEPLVLLDSVSELLELNSQDFPYKYAEYIRRATLVLEPLKRQLLRMKISKVYGFEQSMEHLSCVPPKNTRLPINVIFQNASYLSEVHDKHDNHREWFVIVNDTFAKPATGLFTCVNEVDQSYYINPNSKAVFGEDHLNCFYATGRVIGRALLHGDLMAFHLATPLLKILLGLPLSFHDLEHFDPVTYKNLKYLLENDNVESLDLDFSIQEKRGDEIVTIDLIPNGRNVGVTDANKKEYLMRRAQHVHVESVSSQLYALCKGFYEVVPQELLLIFDPEEIDYVLCGSDEIDVGEWERTTRFNQYLYQHPVKKWFWQLVREMPLDYKKRLLHFTTGSTRVPIGGFSALSSSDGRLAPFTLQSIELVDSRSLRSFSCFNRLELPLYIKKSELKANLLSLLAPENYEHACD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8H9</accession>
    <name>A0A8K1C8H9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ryanodine-inositol 1,4,5-triphosphate receptor Ca2 channel (RIR-CaC) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013386</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polycystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8H9"/>
    <dbReference type="OrthoDB" id="300855at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.160">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046791">
        <property type="entry name" value="Polycystin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003032">
        <property type="entry name" value="Ryanodine_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF183">
        <property type="entry name" value="AT14535P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20519">
        <property type="entry name" value="Polycystin_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02026">
        <property type="entry name" value="RyR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin" evidence="9">
        <location>
            <begin position="151"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="8">
        <location>
            <begin position="354"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Ryanodine receptor Ryr" evidence="7">
        <location>
            <begin position="889"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="Ryanodine receptor Ryr" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1147" mass="130670" checksum="647D0AE96C7EB1AC" modified="2022-08-03" version="1">MASLAQHVDATDDNDAVSMTSGDADTSVKKPTGRLATFVRTHRAAKGFVNILETRSSRVFNGIHMGEKKLDVKAVVAEFKESKRRQFYQELVVYVVFLLNFFAFVRWLPVQDSYYQNDVVGHLTCREDSVCELSKFGDVYDFATTMSEHICDHKDVTAQWLRVGGVRFRQVRVQEGLCRLYDGWSTPCYPFYSPNVEFKDSIVSVDQQRVYSWKEGLGPLTPRLSSSVFEWMFASSSQEEDFGSGGYAVDLCNANVSDLQDDEWLSVATRAFSIEFILVNPVTRVFTVGWHVFTVNPSGHMKHFPHAANLRVLGLEDLELEGSARPIVPSEPLTGLERVSDAVSTVLDIVDRWILLWCALVLFFFAYCIAEATEMTTMGATTYLNSDMWNIFELAHLVLLASMLIYAALYYRASGEFVVHLDDITNGKSMDKVNHSVVQELLRSFQQFSDLASLTAAISLLKVFKFLRMNSTLNLLWRVLGMATRDLMGFLVIFNLIFLGYSAMGSFAFGFALEEFSTISNSYATCFRMLAGELDYPRLHQANPRLAPVFIVTFVVLVFQILVNMFVAILSEYYESAKDEDDDDDVEYDVLTRVRQYLKAFSPTVVVKKNEAVRLLPGQVVRLISTNLVDREQTRQRVKKLFRGAVWRVVALLRFGMKFDRRILSTHRSSIAPPMREADNMSSHICLSEDFDHKTIKEMIPIGITIRLQGDSLLGDSVALKVVRHNNFSVECVVLGLVESSGGHGSSFQRSNSGGSFSDSDSDAFERVVELVGGEKLRIPSYVFAFHLSKMLFKEIQASLLQATKLFNYSKTHLVDDYHLLILFETLRKEGNTSLRYDEVYRMLDLYLRKDKKSHSTPQQVRQETMQVMYRFRNALIDMPSREKEGHNYRPKPVDTSSIQLGHLEHLADMLAQNSHDVWALERLKQGWNFGPQRDDTKKLHPNLVPYQLLPSDEQQYDYRSSVETIKTIMFMNYSIVRGSGSFHASSSSLSATDVEISMALNSIDEAEADAKPKAKDFVPSFVREAMRFRHSSILEDSPYATVYEEASDRVYRPLPIDTSKIELPTRLMHLVDLLAENSHEIWAKGRMDEGWTYGPQRDDQAKKHPGLVPYIFLTDDEKEYDLNIAMEMLKTLLALNFTIVQRSNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9P7</accession>
    <name>A0A8K1C9P7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9P7"/>
    <dbReference type="OrthoDB" id="165447at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="61661" checksum="F176D3E15C458680" modified="2022-08-03" version="1">MPEPETKQIHVLVVVPSDEVEAKRRRMTGTFQGVIETPPPTERFDPVPPPAVHNVNYVTVPAALLDKCGLLTPEADKVMLYRRREVQDLWDFVQEEVISKNASVYIVGPPGIGKSFSTLCFVAQLDPSQWNVVWIHFGASTTSCLSMGGREYWEDIDESTFVVPRVAGKRLLVCLDGYNVNLAHLGFLRKIKRGLTKDERHLVCSSIATLGKLNQEDAEREQIRVFYMYSWTLADYEAAVADAAFYEQVVSKLDATTANEVNDDSDDEEGGEAEKKKDALDRKFYYAGGSCRFMFQRTTDQVKQRLQRAMESTTNKTDLIQYCSGNWHHDTINTLYGMAGGEGGRFPVSSYAASLFAKESGAETIVQLASRLNTSKNPAMDGHLLEWLFLASVPKRAVKLVGDDGVIDELPTAHVLEFDPKKRFRVSNGRIMGNKSWLQPVAWNQGGYDAVYFDNDKGNVIFIQVTRSGTHSFKMRFFNEVLLKLKAAKMTIKTVEVYFVVKSAQYLKFTIGQIDDRDLLWKFDARWKQPEENHVKVRAFEAVGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAI7</accession>
    <name>A0A8K1CAI7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAI7"/>
    <dbReference type="OrthoDB" id="163959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035420278" evidence="2">
        <location>
            <begin position="23"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="606" mass="64113" checksum="83598A74C49C9136" modified="2022-08-03" version="1">MFGKKLILIAAAVALAVGSTTAKPEGIKISLHVRDGSHHTDASSIAITANDTIVVESGSLEVDDEESEERDGDDDEEDEEEEESEEGDDDEEEEDEEEEEEEEEEEEEEEESEDGDVTPTPASNSTTTATETEETEITIWVEGETGPSTTPDCSGDGESPMSVEGVEGVFCVHEQACVADIKDGNCPEPQEGLEFGAYCGTVKSGVQGCKPYSSLEEWEAGQAKHKAKKAKKAVKKVVKKAHKAKKDAVCTGPNQSPMSVEGVEGVFCVTGQSCVADIKGACPEPAANLPYGGYCDKVKTGVYGCKPKTKEMWDAEHAGQENASADCSGPNESPMSVEGVEGVYCVSGQACVANILGACPGPQDGLPLGAYCDKVKTGVYGCKPYTSVRHFKKPLKKAHKVKKAHKAKKDAVCTGPNQSPMSVEGVEGVFCVTGQSCVADIKGACPEPAANLPYGGYCDKVKTGVYGCKPKTKEMWDAEHAGEEDASADCGDGESPMSVEGVEGIFCVSGQSCVADIMGNCPGPQEGLEHGAHCGTVKTGVLGCKPNTSAHKHHFKHATVSKPKAHPKKVVKKHAVVKKPKKVVKKVMKKVVGKVHPPKKHSPKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAR0</accession>
    <name>A0A8K1CAR0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004444</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAR0"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="177"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="47348" checksum="CF669BDA477DDD9A" modified="2022-08-03" version="1">MAAADLLLSEGVGTFFAVTALCTASVGFMLQFSTLVVVCLALVAVIFMVFVWCALAASCETIWELPRTILDIQLAVVRTVLGIASRGFRPRFPQWTLRFEVARAVMSAMRQGRSAQNIVTARNAQYFRQQINLVGTMKATAACQEFGTMVNPLNMNEMEHLWVRSKRDMRSKTRLVVLYFHGGGYVHFGPRFYVELANRLRAGILTKLQQLDANQAENVTVEVLLANYRKSPEHQFPVPQQDALSMYKYLIEREGIPANHIIVAGDSAGGGLAISTLLRIRDETSLPQPAAAVLICPMADLADDPSADKARDRHCILTVPMLRAFIHAFHPTPADPKTWKDAASAYCDLRGLPPAYIQTGMCDTIHQDSVKLYAKAQADGLTTWEYDAFEHMPHAFVIVPSKILPEADRGMDHAADFVARHWVKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAV2</accession>
    <name>A0A8K1CAV2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAV2"/>
    <dbReference type="OrthoDB" id="157199at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="610" mass="67396" checksum="92359DCB11C77B97" modified="2022-08-03" version="1">MICTAIYVVFATLLAVCAYGLHSIANLPINLGIVEQSWSRDIFDISVNTFMQGKTTMKAIAAANTTDLYGTESLADLQYDTCGVRDWECADKVRPNTEQVLHLLASTFNTIPQFETPELAKRSDELTVEYVNQLTGYNFPVVQYSLAGVESKSTWAVVCSVRRTRYRVAQEEADEIDSVAICSKRRYDPDWICENEVEKDTTSYIVKIKHGQVKYLGQTPRGELYYNPGNVVTLRGSTQGTGLLSTVIGIDEYNGGIIQSSAPWDIAPAYLCKGTFNFDTYVGMRWQGQGLVNMTWTSGSLLLTNSLVLWAITMSLALLQFLYLPKSSVCVLPVEMAKSFVGPIILGFACYGNYHVQILTTHLHLNKVTSFDTTPLKLCGPAMFASVIGIMSGTTIQAAFNPLLVAPSYVLTIVSVVNWLVVFALEAYVFPRQSVMLPHQCGLKTSTTCSYYSATTRNYYISSLVALVIVIIGMVVILIIQRHRAKHVMVCSRNSVLRLFSVDALGDLATSDTGGCVVVGPEDVPVVDAGVLLNKNLIRVSSISIVRVGMVKYVILWRFLPPFLSRLVSHVVGLTLVIKASQDRVVKEFAFLELKDMKLHTAKELPAYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBB2</accession>
    <name>A0A8K1CBB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004582</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="12">Interacts with PI4KB. This binding competes with FREQ/NCS1 binding in a calcium-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Golgi apparatus</location>
            <location evidence="11">trans-Golgi network membrane</location>
            <topology evidence="11">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBB2"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051111">
        <property type="entry name" value="Ca-binding_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001751">
        <property type="entry name" value="S100/CaBP7/8-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46311">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46311:SF5">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00303">
        <property type="entry name" value="S100_CABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW59513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="30897" checksum="0A4D0C5BEC3BE298" modified="2022-08-03" version="1">MPTGDAASKSHNKAVVSQEWWRTEPNPTTNHVTAKERYQEALDDVRRLDQNRWLGKRAKKRRFEFSAEQKRMLRQWFNALDADGSGKISVEELEDPMLSIGIVSDRNEIKEIVSRLDKDANGLIDFREFVDFLTPHARHSKDVLGKHEQMFMLLTKKMEHQSAGFLEINTQLSMERRRFILDAITHRSAQALMEDIAQLKVPTAAELRGSPKDRQNLRHQRSMARKIKLEALATQHEVEMRFQALQDVLTRNSQLSVSSTSDVQHVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBF8</accession>
    <name>A0A8K1CBF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000082</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBF8"/>
    <dbReference type="OrthoDB" id="76756at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07834">
        <property type="entry name" value="STKc_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000961">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="9">
        <location>
            <begin position="158"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="517"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="355"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="460"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="883" mass="98913" checksum="A907D962E2F729E8" modified="2022-08-03" version="1">MHTTRSLDGRRRLSASAASDHGGHVYLRRSPVNPSVVEDTTDKYATPPHARRTLLGRWFRMKAGRLRTYDGSEERHSPSSHRSTPTGRHMSNQDAFPDQPPPLPPRVRNVHAALPGGVARAISNSQRASRGSMSMSSSSSSSSGGSARAKTHSLPTTRVLMEGMLVKLSSHKYWHAKPTYFVLVEEASASAMRSRIALRQYRKVEDARERDPRRALLLEIILSENDVIVDISDRYIKYGIELHHRANADNTVAVPTTGELYSLRLSASDSTAHHLWMRVLGSAIARLIDHSKRHYPITPADLEFAKEKTSLEPNAVKAIVSKAVPGRASDGLKRKVSSHELDSAFAAAFSRSAESSEAMSQDEPEQVAIFQNDDNRRVRRQSQRETDDSNNNNNSDDEDGKSENNQHEDDLEVTRLSNASISTPELSDDDGMPPPPPPGSPPAEPEVDDHLSVAMAASVLSPSTNTRNLRRRPPPPPPPVPAPVAPFLPTRTMMMMPRAQVHSFSANGQVFTLDVRYRLIKSIGTGAYGAVIAVKDSKDETNVAVKKITNIFDDLVDAKRILREVRLLRHFHHKNITQLLDLAPPLSKKHFEDMYIVTELMETDLHQVIYSMQPMSDDHVKYFLYQMLCALYHIHSAGVIHRDMKPSNILLNSNCDLKVCDFGLARGGISFDPRQRMDLTEYVVTRWYRAPEIMLNCLHYTTAIDVWAVGCIFAEMLLREPLFPGNDYIDQLKLIIKFLGTPKQEDIAFVKNVKALRFLTKLAISKPKKWLDVFTSDEINPLALDLLSKMLIFNPAKRITVEQALLHPYLATFYDPIDITFAQPFDFGFDLPDDKLTKDALVDLLLEDIAYFHPTVQYSMPPPPQSSSPGIARRYFGMTASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ8</accession>
    <name>A0A8K1CBQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1939344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF8">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="553"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="755"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="947"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="947"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1337" mass="150739" checksum="7226DCFAE6BCE31F" modified="2022-08-03" version="1">MESSSPSFPPTMTAPHVYPVAAASTGKRADSGVALGLFSKIAAARKEKLSPFSGALYTESSNDRAFERRGSTPPLPGSQFPEIHDPPIRSMPIARGIPPNPRKVTSRAFAQNLRWSKLEDARVSRTPLGPPPVRTPPIRSTLEKVRRASAEPSTPPSIISERILPLDELGTRPATAGDDPGISNVRGFVRRSLDLTNNLELPVATRRAAEWSSKPRTVDSSRASPSLKHHADILVLEATVSKSPPETVPDVPEQEIYFAETDAAPGMPIVYRHQKAKALNPERLNLDRRNLAVVPLLEGETMLRLLNLQNNVIRKIENLMGLPNLIFLDLYNNRIEKLENFHAVPNLRVLMLGKNRLKRIEHLESLKKLDVLDLHSNEIERMENLNDLVELRVLNLGGNRIKTLEGIERLSLLTELNLRRNHVDRLGDIGRLPSLQRLFLSNNHLETLEALEPLLHVTSLVELRLDNNSVCDSNQSEYRARMIKSFPLLKHLDLRPLSDTERKESLVQQTQSTKNATKEREELEERERTQLLSLIRSQWERRDKGGVTSMIAARKRPSRSDLSSTTSAWGATGPSQGNRLRARSSASVINSTIEEDDKQIEVKPTNREDFTIHRNKSGISEIEVHNEYRILSIYGDALDALESAKLHTSVNAIKFRYVSIERIATVATSASSSNLKLFARLRRLNFAHNDIESLEQLAWIATMGTKAEELFITHNAVCLRALFRPYVAIRLSNVIRLNGEEIALAERQIGRQLFPKASRPKPPETLLESALPKTQRENRPPTRSGVAVNAAAEIVSNAADIEKKEALLEASWSDLLAAVVKETLTDISQRESCLSGLYQTTDDHWCNFYFHSLTSIHQLVIMDSSEAWNSATDTGFLEAEGLLESIELDTDDLSGLLTCLSPLNPNDDDNIIAPSLAKAERPSAALSVSNSDGGDSFDGRIWRFDGETSSASSRSSEAATRPSKCKRPRRSDSNKAREERRRELLCLRQSATQLEQELASLQLEKGPVTTIQKQQDGAEAQLRLHHRLGPWETIAAHQKRERRRVEEENVRLRVELDTQLKFATKLERLVRQSLRQQAAEGYHHGDALQRYMDHSQLHDRSVFEALIRAMEQQYQHVANRFDRLGINDIEYSHHGSRVYRRESGVEIEVFHNEVLPVSIEVAGDIVWHNYAYYMAQVPHRHYYQRTREVVYTSADTILEVIGIKFNFNGISAHVREQQVIRRFVEADRIVIMLCSNFHTVEYSDRPTVGMVFRRNGCLLFKRPKTFDPSELSVLKTSTITTPMLDGAQLNPSGVMVKELVDFLLSEGAASAAIMHQVIENMLMREAIRTKRPQLRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBZ0</accession>
    <name>A0A8K1CBZ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBZ0"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="118"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="29201" checksum="1E4D438A326E3C18" modified="2022-08-03" version="1">MSSILASLDMSLDDIIAKKKTNPDARPAKNYRPQQTGSAGPVRGNRRNHRRNEPYSRRGDGDDDLMDIEDDQPAASKKGPAAKRKAVVVKNKQQDKGGKKGSILSRLGKASNPANEGTKILVKNLQFDILEDEVRELFETVGKVTKAEIVYDRSGRSKGVARVWFAKRSDAEKAIKQYDGRTLDQQPMQITLDGDKNVRNGLFGTALSKREDDGVKFKVNLGGKKDQRDQKGRGRGRGGRGGGRGGGAPKTAEDLNDEMDTYMKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC83</accession>
    <name>A0A8K1CC83_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC83"/>
    <dbReference type="OrthoDB" id="123108at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="351" mass="39064" checksum="DD61A20AB02C1386" modified="2022-08-03" version="1">MPATEVSPSLRRRLSDDARQLLRSALGCPSRFEGDNFAKLSLAQRLQHFRGVIRLELPGVRSSVRLRIAVDETSYLIRYNLESIGAEVSVVNKNGATTAWITTADGTHMQLRAFVHSDTTPNDVRVQITTFVDLLEAVDLFDVFRACLTAREIRTSPTSVTSNPNRELHTSSTEKSSYVFVVDQVSGKPLSVTQTSMVNSPTQKAGSETMRLVVEDYIRYDGGVDVPVGIKSDVEIMIDTAMVCFSQWSVDGQQRAMHVFNLVDKDDDSFISSHDVYVQLLSVGHSQQQCANIVMEMSRLLCDTSDPAEEFGFYKFCGFWVTMLADQYRVSDPANESSVLQAFEGLFLGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ4</accession>
    <name>A0A8K1CCQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_004991</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="9">
        <location>
            <begin position="711"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="10">
        <location>
            <begin position="898"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="8">
        <location>
            <begin position="1209"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1276"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1463"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1280"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1291"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1311"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1330"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1486"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1527"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1583"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1629"/>
            <end position="1640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW59922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1640" mass="182109" checksum="38A7523CB8D06D49" modified="2022-08-03" version="1">MGIPRFYRYISERYPLINQPISDVSLLPEFDAFYLDMNGIIHNCTHTDAADSELNRLGLPAQLHNIFTYMDRLITHIIKPKQLVYIAIDGVAPRAKLNQQRSRRFRAGMEREEALAKEKHHQIKLEDEKNGHSATPPPQRFDSNCITPGTQFLTELSAHLVWFVRYKMKTDPLWSRLEVFFSGSEVPGEGEHKIVDFIRRRKMAPGYSPNVRHCMYGSDADLMLLGLMTHEPHFTLVREVVVWGSKTHKVTAKKIEEEQWQLVHLSLFREYLMMEMRVVVPLDGERMLDDFILLTYLLGNDFIPHSPTLEISEDAIPLLMRVYREHLDKHGGQYLTENGQLININLLQDLFETIGAMEEDILIDRAIEEAKRHGKHKRAYNERRTGPSVEVNEDAVANAINLLNDGDDDDQPPPLIDDEEEDDDIGVSDEEAKERELLEALDGELEAKLALEKEEEEREIFSQLTGSESFQDTKWTYYERKFGIQRGNGSANNAELERVKKHYLEAIVWCLHYYFQGPPSWSWYYPYHYAPMVSDLTNIADVVKDIKFGNDPTTDGPLLPFEQLMANLPSTSAHLVPEPYRFLMMSPLSPIKHFYPEKFEIDMEGKRNPWEGVNLLPFIDVALLKSAIAQYCPENRLTKAERQRNRLQLLPLRISYDPQAYETVPSTMPGYPGFPDIAACCTRVSEYSLPDITSYEGQFQSRLMDGVTLPMAGFPSLYTVPLESVRVEHIRVNCFGMGSRKATLILQLPPTGRLEEAVNPQELLGKTALVNWPNLHEALVVGISTLAGEYRLNRNSTDVAFTPFDNDKKVEWAQYAQSEVYRLLCGRGTPGSGGLDLGQTGIACVLHVLPLQGMISNPVTGAIEKKFGQTEALVPLQLAVVDRKLHDERFEETGPMALEERFPVDSVALITKGKWLGCTAVIQKCDGSRNKVTVRVNTIDKEPPFGYVVAQQISDKYYPGYMVAQKLGISTTTLGLLTGSVVIKPTGQEIGLNLRFRKDLLLPGYCRLVNKAASSSGGAGDENNVWRKGDIVKIVGSGVSLEREEQQAKRANGNGSGGGTTWEYTDRTIAVLAAYKAEFPEVFINLDKLSFATQYGGKEIFGTSDKKIIQDKADAVVAWIEQQQLGKKEHSKHIPINSQYISLNAMRAIEAAGALRAKEREKSAAQQVSNPVAVDVAPAELFRPNPLVNQDLTGSVVAEQATKNPGAPRLGDRVINISARGVPFGQRGTVVATHVTSKCVEVLFDEGFTGGEPLYGSISLNRGKIVPWTNVICVSTPPGEENKTQSRDQRGQQQTSRRQSNSRQTQQQSQPLQPGSNKITSNYRQPRKGKTMETEPHAEVEAADPPVQTSAPAPAPPDPEKIKMLMAKWTQKGSVEYQAQSTEVEATAPEVAGEEVVPSVAALFSAAAQATAPPPSESANLLATLFPRLAEGNSNIEAPETPAAPVNESANLLASLFPHMAEGNSSSVAPPLPPHPVSFLPHGIPGQPPMPPMPPQAFPPFMHPHQPPFPPSGYPPYPPYPLPPQQDQHKPRENRRGSKEKAPAPVASLTEYPPLGAAPPTAQQKKEDTTTDEPATNSEDKKKRTPRNKPRNKSANGEKAWVPKDASSTDAATPPPAANKPSLLLPSQVMRQQKPSTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCZ0</accession>
    <name>A0A8K1CCZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCZ0"/>
    <dbReference type="OrthoDB" id="669460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052776">
        <property type="entry name" value="Chloro_ReproSupport/MetalTrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33876:SF4">
        <property type="entry name" value="CHLOROPLAST PROTEIN FOR GROWTH AND FERTILITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33876">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="37435" checksum="2757CF2253C9836A" modified="2022-08-03" version="1">MTSSWTMTRQLSGEDSSLTHASVGHIIGTGVLLGVVHVLTGPDHLSALAAMTTNSSWKAFALGIRWGCGHSLGLIIMALIFFAAGRSFDLNKVGVYCNYIVGVFMIALGLWTMYHIRKKYQKQLKADTESVRCTPSTPVVVRVHSNGSNEVTHEAMVPLASRQASHEIHIQEHEEHCESPNVSPFHLVDGHSDDLPSQSDGRSSRRLSQTSSMDANKLQSSKPGRCSPRRCTNWSFHNPATQRVTALIVGIVHGIAGPGGILGVLPAVVMDNWGKSVAYLASFCVSSILIMGVFAALYGEITGRLSRNSVLIEFRIGIFSSMFSIVVGVAWIILQATGQFNKIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD04</accession>
    <name>A0A8K1CD04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000587</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD04"/>
    <dbReference type="OrthoDB" id="74661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="48749" checksum="B40776D31F6C34C1" modified="2022-08-03" version="1">MDEVELNCAVYGEGSVFPVKIARDAKVSALQEAIADIVSTEQHAVPPRLVTLYLARKKEGENDVWLKSDATFEGFLRRGRQKDEEYPYGKMIPNWILGEDYLGANFQPGRKEIHVLVDLPEGATGEKSETAQMVKEIHDQVVQTKRKRYVHSEMSSNKGNALLQDLNIRVKPARLVPFTTEDPTPAEAFTWESVCDEHDQLIVLAEEQQRERYRTYVEDNIGDVLAKKQLCVLGMEKGKNILSATVPGHNVELVGRTDMLILSDLAKQEPLHLEWLPEVKMLIEVKRNVKGGSVFQALSELIALDVLVDDPVMALLTDLTGHWQFFWVSEKSDNRVIIRTVIISDPSAAFAVIRTLLAQSPTGDADITLPCFEGPVKRRKLAQLLPSIGEGGESSGIRAAIERYYDIASVLGPDIDMARAAAHQIVRTIPTFNYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD34</accession>
    <name>A0A8K1CD34_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD34"/>
    <dbReference type="OrthoDB" id="119209at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="16278" checksum="2D0D707DBBC72B9D" modified="2022-08-03" version="1">MRAPPQATTLKRTCALDDTFDESLEEDRGVKGKGKKKATAKGKKRSSANVGVDKENAENNAARKVKVPVRKRARRSLGLQELGETDKTAAHTTETPPAFTFKQGKTSLRERKIQKQKRLSEDTSQSRIEELVAYFSGLDEQRLSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDL1</accession>
    <name>A0A8K1CDL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease ATP-binding subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014514</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDL1"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19497">
        <property type="entry name" value="RecA-like_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001520">
        <property type="entry name" value="ATP-dependent Clp protease, ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003745">
        <property type="entry name" value="PRK05342.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="371"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="578"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="693" mass="74535" checksum="9CFF414F01B62C3D" modified="2022-08-03" version="1">MLRRLRVDAAAVARSSNSKSRARLSSVRLQTLAERRLRPFSGRSLANPALRAVQIVPTRQFCSKGPVKKGDPLCCPQCGSALTLAESLAEAAAPKPSTPPSPASADANAHAFKEGDVVKCTACNLHFAVKAASNMSTRSMGPTPAPSPYRNAAAAAALSSLSSSLLAGTIQARGSSLDSAASPTAMAGGHNIPSAAQRRRMNADGEYEKLANEAFASTGSPLRAGSAFAASKLIKQRVLTPREIYDGLNQYVIGQDNVKRILSVGVHNHYKRLQAIELLNAKKELAKTQHNASSHVPSITGLLDHVDDSHASHNDRLLLEEVWMDNTHNRDSVPSKDAASASASSSSETPTSSPPPSRLDKLEYLDGVELDKTNVLLIGPTGSGKTLLAKTLARLANVPIVIADATCLTQAGYVGEDVESVLFKLYQASNYNLEATQRGIVYIDEIDKISRKSENVSITRDVSGEGVQQALLKMLEGSLVNVPEKGGRKNPRGEYITIDTTNILFICGGAFAGLEQLVNRRTQRSSIGFGAQMRNTRMTEAAHMGSLMQRADPEDLVAFGMIPEFIGRFPLLVSTTGLTRDELVQVLTEPKNSLVKQYKALFAMSGVEFHATEGALEAVADLALKRNTGARGLRSIFERALIDTMFELPDLTDVNAVYVDEDAILERKKPVLIRGDVTLDDYLKNHDDEAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDM2</accession>
    <name>A0A8K1CDM2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDM2"/>
    <dbReference type="OrthoDB" id="167385at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="56979" checksum="6CF2817A4A95D7B5" modified="2022-08-03" version="1">MMAMATQDSLLQGLLMDEDLEEMIATATDDAMLWDSLDFFNKDAEEEPAEAMPVLPVTTSRSKQKAPLSTFSTSSSSGDEEMDEKALKRQQHRKAMQLCRERKRSRMGALEGEEKRLLQLLFQKLRLHEHQRHFQITSDVYNEAFMTRAEQLRNEFIDLLLLKESLEGEKGTLEASLSEHKRFARLLTLSKAQMEKESLLREIDEMSGDSERNITKALEEMEDENGGRWVRYVDTEPPFYYEPIDEEECAQWVRECYQRVRRLHSGFLLEQFPDIGVTHCFGWRAERSLSTNEQNQRILRFRFTRRVPRSYASLEAIQQRAWEIFNTPSLIARLYSSVVVAKVLQNINDDTVILLRNSPVRDRLLNLRYFSVNSRMEYTTDANERAVMLLMMLMDKEPPKKEIPSDMAKEASKTPAPQVTWLKDGTMYFTMTEKPRAEGEDEDAIEIEHGGMIRCVNEEQVRYLLVEIAMVLIRWEQISVMTPLLLTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDR0</accession>
    <name>A0A8K1CDR0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDR0"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="157" mass="17267" checksum="38014CF6D71281FE" modified="2022-08-03" version="1">MTLPSYVVDVVRKQLAECAEDAPLSGVSAVVRDDTEALERLQGSILGPEGSPYEGGVFLVDIVIPPTYPFRPPTFRFETMVWHPNISSEDGSLCMFSEEVWSPALKLNTALITIRGLLSSPDPTEPHDVDAASMCLNHPELFDKIARSWTENYAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE23</accession>
    <name>A0A8K1CE23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE23"/>
    <dbReference type="OrthoDB" id="10067602at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22985">
        <property type="entry name" value="DD_CrRSP11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="129" mass="15276" checksum="77B908EA70EAE92E" modified="2022-08-03" version="1">MDVNRIFSAEQIAVPPDLPHVIKEWTKSVIRENPEDVLYFSLKWFQDKTNLASQKKATENQIRRMRQLFEQYDVDGNGRMEAKELKRFFLEDLGLPMTENDVEDVMMDLDGDNTGFIELSDIIQWYTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEQ9</accession>
    <name>A0A8K1CEQ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEQ9"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="32157" checksum="445E6F4F214577CD" modified="2022-08-03" version="1">MPATTTTAPPRLLVTGASGQLGLVTLHHLLHTLLVDPQHIVVGTRAVDSDALKTYKDQGVDVRFFDANDAVSIAAAAKGVQRALLISNRENDDGASHALAIREFVTAGVQHIVYTSLQAADVSLAAIAPIHRKTEEYLKQSGVPSYTILRNGMYFENVFPSLSVVSKTGGQWLSAAGSGKLACVSRDDTGRAAAYALASADRVESATLTITGPEALTIKEITSNISEVVGKPIEVVHLSREELALRLVEVLSLPPPVGHIFASLDATTAAGVASTVTGDYELLTGVSPVPHREWSKASQHILASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFC5</accession>
    <name>A0A8K1CFC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFC5"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="58"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="162"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="277"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="40882" checksum="0DC890E73DA85987" modified="2022-08-03" version="1">MAQHGDHQNAASEALPRRVSLRRHTTGVVSLGEAGDVALETADVDVQLIQKDGRKQFLKHSSVLFAGGVAGSVGKTVTAPLSRLTILFQVHSMVSTRHTDRFSPTLGGAFNKVLRNEGFFALWKGNGASVLHRFPYSAVNFFTFEVVKTSLIAQQHPMFTDNSWTTMFLSGALAGATATVACYPIDLIRTRLATQLNTDIRYHGIVHAAKRIRAEEGFRGLYRGMGATLMVTVPNLAINFTLYEDFKERAKDFRRMQRSRGLEGREKAAKEAEDFQLGVMDTLLSGGLAGIASSLVTFPVDVIRRRLQISAIHAGTHNIPPTPWGIALELYHTQGVRGFYRGLTPELMKVVPMVGITFGTFERLKNLLIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFL8</accession>
    <name>A0A8K1CFL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFL8"/>
    <dbReference type="OrthoDB" id="1476984at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03114">
        <property type="entry name" value="MMAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006958">
        <property type="entry name" value="PRK09435.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408:SF3">
        <property type="entry name" value="METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="METHYLMALONYL-COA MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03308">
        <property type="entry name" value="MeaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="77"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="39237" checksum="CD36C0DA414964DA" modified="2022-08-03" version="1">MATAADAGEDAVAEMLPITKKLVEGVTAGNRTALSRAITLVESTLKSDGEQAELLLDEVLKRRRDIRNRQTKLQALPSFRLGIAGPPGAGKSTFIEALGQYLTKKGHKVAVLAIDPSSSRTGGSILGDKTRMTYLSNDPNAFVRPSPSRGTLGGVAQHTNDIVLLCEAAGYDIVLVESVGLGQSEIVIDDTVDMVMLLVPPAGGDELQGSKKGIMEIADIVVVNKADGDLKSAAKHAAVDFMHAFQLLRRKDPDWEPKVRMCSSIENTGVDKVWEICEEYRRTMNSLNKIAQKRNDQSSKWMWNQLNEQLMRAVSRDTRVREKAEKMNQDLVLGFISPRSAAAHVLDLFLKSQDNFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFY1</accession>
    <name>A0A8K1CFY1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFY1"/>
    <dbReference type="OrthoDB" id="153600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423807" evidence="1">
        <location>
            <begin position="32"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="22389" checksum="0A3625D16D602E73" modified="2022-08-03" version="1">MSSFATTPTRLAAATAIAALVLTENLPQVDAHGYISLPAASYGNSYTKTNYDALISAGVNPAFSGRKWNGSPEANAQQFTEAFHAGGFSSLKALLDPAAPGCGNSRLDVPPVDVSSLSVMQFRNDEEQKGFIDSHHGPCEAWIDGTRVFHSDDCRAQFSGYPASIPINYGACHGKCTLTFYWLAVHEAQWQVYKQCVPIQNGGTRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG57</accession>
    <name>A0A8K1CG57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005037</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG57"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14690">
        <property type="entry name" value="bZIP_CREB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="179"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="197"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="48878" checksum="85E099A061E7D094" modified="2022-08-03" version="1">MSATNGGAEPTESVQTTSGIDWSIFRDGEDDTFTWLWRTNAAAPDALAGMGPPSLVEATGALNSTASIAQSASTPLVPPVASTPAPKQPALLQRSEMPAQSQQVINLEDDDDDDEFDQDDFDDDDEYDDDQDQGDLLHTGSDKSNNEQASQSANQQQQGGKGGKRLGKRRKGSSGVDEEKKKQQRRVKNLASVREFRKRKMKQQEENEARLRRLEAENMDLKMRLKIGKEALVSEQREKQQIKEQMREMLQRGASEQEVARFLNMYKVTYSDYGPKRREKIQFHLARIRELLLPTQVTKLSLYSVEQGSEMIARDRDLNEDTTSAVDAGMAPMSLWGILAKELNVSAAQQRQILERRASIQRVRDDLNETLGIVKQLEQVTEDKNTALEAHIAELQRILTPSQATKFIIWVKENPAFMYMLDKLVDSTLMGTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGQ6</accession>
    <name>A0A8K1CGQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGQ6"/>
    <dbReference type="OrthoDB" id="123092at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="194"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="515" mass="57703" checksum="A5680FB963861916" modified="2022-08-03" version="1">MKENAGGLQLLSPTLQRGLQKTKSALSNNQTETPVKKPLPVAVFDFDGFTLDAVRRRHEKEEERASSNQKQGGNRSFLQSMSTTTTSSSFAESPPSPSMLRPSSRYQSSERPTSSSGDAFETGSIRSLEDFEWGAGPSVRNGQRMTSSNQYQQQFNSFSTSTLNKRLSMASSNTSSSLPPQSLPGFAPIKEKAEVVMQGYLQRRRGRVIKRWKTQYCLLKADHKLSFYANENTVNGKLEGRFQVLRVTYLERHGSFQVIGVGVDETLFKEEFRAVNEDGWRSWFRAFRGFFDEISLREAYDRIPELEFESDSQSGNNLQYGDEDDQDFVQEVEEMIMRPYAFGASSTTSSPRRKHSDYDTRNSLSNLSNLSGASGSYGQSHQQPRRKASTVVRPSVEPVRRPLSNQLDLNELADDLPMYLSSSQLGNKFASSQNAQVKPTKSMRSTSIDRRRSSHPPRMEAGEDCAENGMSAPGLVDCPMIERDSEVNPVPILEIRNSESVVARDSDGGFSWNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGZ9</accession>
    <name>A0A8K1CGZ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGZ9"/>
    <dbReference type="OrthoDB" id="59157at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08507">
        <property type="entry name" value="COPI_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="28408" checksum="1ADDE25F9A40721D" modified="2022-08-03" version="1">MDLPDEELKQPLVPTIDVDSQPTGGITPTRSPKHSGRGGSPKRKGLVPSEPLRIGGGGATGAHYVAMRGAMGDGGEEEEKEEKGLHDKRQLPYAAPNVHPYAVPQYQPNAYGGRGGGWGGDQVFDQSRIPAIDIIFSGMYTLAAALTVIQGFGMLIQFSIASIILGLYTMAFGCVVILYDLKSVVYGVSVEQYFPFLGNYIGRALTISFFAALCAQTYTYSGWTKFIMWYNLVVATLQGFVHFTTRTVTPTEHSAMEDLPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHA6</accession>
    <name>A0A8K1CHA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHA6"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="908"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="965" mass="109338" checksum="CF8DBE64382CB1A7" modified="2022-08-03" version="1">MVLQSFLDRDQLVETILALDAKHAVLGLLMGIAALRCASWLRSKDLVSKGVTMPLVPSSTLPIIHNTLDFAMHTSDFHDWLLGLCEQFHGRTFVLRTLGRPDVVVLTTSESIEDVMKTHFENFLKGDHQYQVFGDMLGKGIFATDGMNWVHQRKVASNLFTARTLRESMTEVIRKHTVELRRILHDAGTQDKTIDLFNLLNRFTIDAFAEIGFGVSMKSMESEEEHPFQKAFDRVQRATMLRLVRPTWFWKLQKALQIGAERQLREDVRTIDRMVLDIIAQSMHHRHSHGKASDKVDLVSLFLDNYEKNPESNGEEFDPQYLRDIVVNFLIAGRDTTAQALGWFFKNVSMHPEVVAKIRTEIKDVLPQLLTGEIDTPTMEQVQQLTYLEAALKESLRLYSAVPVSSRVAVEDVVLSDGTLIRKGKLSGLFRDGLVAEALQNVDAKQAAVGVIATLTAIKCASWLLSKASEKRKMKRLGATSKPAAPSSTLPFALNTLDFAAHIEELYDWFMTLIEQHQGRPVVLRTLGRHDMVLISTPEGIEDVMKTHFESFPKGDFLHQIMGDLFGKGIFATDGLEWIHQRKVSSNLFTTRTLRDAATKAICKHTTVLRRILHDAGAQGQTVDIFKLFGRFTIETFAEIGFGIKMNAMEAEVEHPFQTAFDCVQRMTMLRFARPTWFWKLQRMLHVGAERELREAITTIDQTVLEIIAQSIQRRQANEKTDGAVDLVMLFLDHYENTPEGKNGQFDTRYMRDIVFSFLIASRDSTAQALSWFFKNISMHPEVAKKIRNEIAEMIPELMDGSIDTPTMEQVQRLTYLEACLKESLRLYPAVPLNAKLAVKDVVLSDGTVIFEGQTVGIPAYANSRMKYVWGPDAAVYNPDRWIDPETGKLTNFSAFKFFSFNAGPRTCLGMNLAMLEMKIVVASLLSRLEIQVLEPEKVTYKFSLTLPVKGEMHTRITPLHARAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHI6</accession>
    <name>A0A8K1CHI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHI6"/>
    <dbReference type="OrthoDB" id="75211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="825" mass="92066" checksum="2B3B6F3EA973F939" modified="2022-08-03" version="1">MKAPPTLPRINEEANATPPATLDDLKDAYNQWLHDLHTTNKTKKKRRSKKSQALRQLQQPTTSSAQKHISSHNTVTATKEKPVDPVEYAVARSEAQRRRFQVLADEVNYAQYQYDPPWEPGLHLFALMARHARTQASQSTGRPTRAELRDFPVQIPPTVMQIRESDCLIIVVLFTASQTQGEEVAHSAASSRGVVSKDRLAPEAAQQYSLHFHYFDSKEAFVRRLAWVLRTMLLVDTTPVQALWKQSGRIQRMPRALCSSSEVEQALLSLWDTPNDIKNLSAVQKYISCKSSVGTTVGSRVWLARSAYRKRDHLTTNVWILTATSATADYVTTIWDSSENAGITTAPCQIVKCANAQSWRQPREIVEALTQWFDLQLRATLGELVIDVLQDTEGQWWLLQVKAFQRRRVTLPLAGIRAKSAPDRLETLSNVSSTTKRKCVGKYCDHVGDPSNNNQANLLATDDDNTPSGFLTKKELLSCEFYDRFSQCDDMSLQNGCVDFAHALAFYLQHQLRKRDRTVLYEPQPLCLACLQRYYDLRTQYLSAIEPSKPQLQARNQATRSQSMKTLNSTKLPALTEAKRTVAPLVSSYSVPSLNDTIPIYEIAPAASYLDELASIERLLAQHDSTSTVAETPTPAISIADTLKTSLSVMPWSNSNTQDRVDEMWERIQLRPLPAIKTPSHTKAPTPQYNSFSLQRALPNTSTSKIDNAFNVHTVSIDDVARIFSDDAYVAEVVRDAVQRLTSKPPQGIRYVVLPNTHEDSATQLSAMARMALGTLYLDLTQAMENELGALSTGSRAAAPITDDPVGGCAVLTILASHFQSVAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHR1</accession>
    <name>A0A8K1CHR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHR1"/>
    <dbReference type="OrthoDB" id="416093at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="85"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42107" checksum="A02175499C6A2E72" modified="2022-08-03" version="1">MPVHASGQESLGEAEEHKDDKTSFLSRKFAGFLRRSSAVNAVRPDDQNVIIPANSIQARIADRRRSSPARIITAVDEEIVFGVKNYAANSSNAARAVNEDRYRIISSLELYGKALVTSDKRVQSYQDALDKQLLECYANEGNVPKMDLKKLAKYQSGTNTEFFGIFDGHGGDHCSSFLALLFPLYLLLTPDFHENMPAAATKACTAINTEILKREEAKQRGGGSTGLVVMIRDGIAYVCNVGDCRAILISKSGVSALSTDHKATNESEKQRIEDAGGMVLYVKGVARVNGRLAVSRAFGDAEHHEYVIAEPEITTHSLSPCDEYIVLASDGLWDVLSNEDVMATIRNHPWLSIDEITQVLIDRAMELGTMDNVTVVIIDVRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI36</accession>
    <name>A0A8K1CI36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI36"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="427"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="325"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="637" mass="70427" checksum="292F88AA270AE0F2" modified="2022-08-03" version="1">MAATATALHASSNAQHNLAALQTQLQTLQLQNAALTKELSVKESHVQRKEQQFRVLQQRMDELELNVALWKEKYREQLTVNSAMTTAKAQMGQAQEHAAWSTYALPASGNDADTEQVAALVDRLSMTDRDRLKTLLAMDKDTMGWSEVFTDVSDELLQVLLQYLVPVLQDAQQRANETKDGNDALTIQCLQRTYTKTATDFRIVCLTQERASAQATAAAAVPRESPTNRMTIAPAASPTSGASTLSSPPTSGDRWSQASMTIERMSSAAMAAALPITTPPPRPSIVKQQEEHLFDCIDCENPKRNPPVPHGPRQIHPHKAVYISRPLHSPVPSPSASSPRRFSTRISSGHHADSASRTSTMPSRSSATGYDGIDGDRRSGTTHGSLTGAPPLGREGSGKIKKIMGNMMKGLHRHKPQLTTAHPQMDEDDSVCDGCGRGPITGYKWVCRTCKLHKDQEYELCEKCYGQGLHGKENEDALLERVEEIVVAKCPKLVHEHDLMRLLRVGICKANLKKYSFCLTWIADLLQCKQTKDLRARALEISQISPQVRSEFVRLLKDLLTKYRRDIELLTEWKPAQNVSVGTSGLEDGAGGLIQLDTLRIWVKDVVTADNRFSLLAQVGQADVWLQVREMGTETRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIF8</accession>
    <name>A0A8K1CIF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIF8"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="3"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="26795" checksum="1A15D3DAE4A8D877" modified="2022-08-03" version="1">MNREGLVFLAKLAENAERYDDMVANVSAIVAQADGDLTDEERTLVSVAYKNIVGMRRASWRVLCSIEKAATHNRPDLVKQLREKVESELAASCNEVIEMTDKSLVPKATNAESKIFYLKMKGDYARYLAEFQSEDAQKSSTALALEAYEAASSVASTELPPTHPVRLGLALNFAVFHYDILESTEDACKLAKQAFDDAIAELDTLSDDSYRDSTLVMQLLRDNLTLWTSDDSKAQDPANDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ04</accession>
    <name>A0A8K1CJ04_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ04"/>
    <dbReference type="OrthoDB" id="2153609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="402"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="416"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="483" mass="56987" checksum="8E54D4299433CA40" modified="2022-08-03" version="1">MAILRRQQEERRNAAVTLQRLFRTRASRKAYLQLREAMKIQLEKVRELVRYAIKLQSNWRGHCGRRNARKAKEEMTKRERHRYDAASRINAGARGYFDRRIAQEERVKRQTRIHAVRVIQRAWRNYLTPSLKQIQFDQMIAKMKSQVVEEGLVASRKQEELLKKAKELFDRDSASEPESDDDWRDFLDDNGHQFWFSPSRNERHYVRPNDFAYQKSMLGMYCRVFWPLEQQWFNGRITRYNHAKNKHRIEYDDGDHEWFCVHIEGDRVQLYNGFCWCMARMFEPSMRTLKAAIYLKLRVQHYDHRYLGWRSGCIQAYNEQSDGFLVQYDDDGSGGGIVEEWIDLFRQEQGVQVQDAITLQWYSLSAYVFGNGQGRPLGILKQTELSSYYGVEDYLNYVEETGSSELVDEATVPETNGEDGEGEVTQDGENDADDEDEDDDEEDEDEDEDEDEDEDGDDGDDESNKASEEEEEEEEDEESEEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJX4</accession>
    <name>A0A8K1CJX4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJX4"/>
    <dbReference type="OrthoDB" id="60372at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20580" checksum="95B295BC2E8540C7" modified="2022-08-03" version="1">MARKQTKKATAAAAAAQNASLSAEQQLQQQVLHHYAKTVYFNDLWKSFLSNISGLVFLMSGFMIQRMNQSKQGIGFIGAFEGLSFIIAACTIFFVRRLVKPLLAFKAAFAFSLLQCLWFGHSYYRRVTKQDPEIGDLWVDQFPFGSMYFALCWLADRFMLRSHDLAKKTAEDVQDVLLKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK72</accession>
    <name>A0A8K1CK72_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK72"/>
    <dbReference type="OrthoDB" id="523796at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052:SF1">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="77" mass="8803" checksum="FF853E58CFCEA86E" modified="2022-08-03" version="1">MGLTGIAVGSFMGLTTKLGSNALQKLPYMRHPWEHVLYIGAGAYIGSFLEKKYHEDLKEVEELRLYLERRPDAARKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CML0</accession>
    <name>A0A8K1CML0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Multifunctional methyltransferase subunit TRM112-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CML0"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21089">
        <property type="entry name" value="Trm112-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15599" checksum="623B16974C2D8C5C" modified="2022-08-03" version="1">MRLLTHNMLVCNVKACQDTAGREPGLRPLNFPLKIVPEMDGVVVMETVFSKTFMLHIMKSIDYPALVQTTKELNHPEVPQLPDQLPTDLENADELLQLIHRVILDTNIVEGELICNNCSRSYVVSNAVPNMLLEEDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN83</accession>
    <name>A0A8K1CN83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN83"/>
    <dbReference type="OrthoDB" id="123202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="561" mass="63395" checksum="C56C48102A5985E7" modified="2022-08-03" version="1">MMIAREAMETALQSYQAYRMSLYVPRVWLNRLFVALLVLNCSVTPLVLVFFKRRPMTCRLLYLLCDCVLDLMSSIGIPLILLPAYVKEFDPKVGGFDLSLSYDDVWYVSAVSELQLVFISSWMDLFSRIVFYAGAISCMKSIKDLLRPKVSQTGKRIGPTTATPMHNSTIQVLPSIPTSNECAITPTTQQMAPLTRSDSPMARRFKHIIHLGFVVWGLTVMTLHLQAEQQEDLTQCLMQVRPWMTSRPACLLLIMDCHHYDVPGSVEDIAPYWDHADEATVTRIVIRHCPQLQIPSKITSYPYLSAIKIYNSTVVQWDDDAALTSRHHPTLSIVLVLRSNFTDGQLPVGLLSADFPPILYDIEFQFSNLRTLPDDIDKKWHSGSYLVFENCQFDHFPLVLQRVVPGVISLAFNRITTVPFEVFQVNGITHLNLAGNPISTLSKPAHETVVDAGSIVSLNLIRTNVSYLPRWIDPLLSRAAPTLSVLLCDSPFCLHRNEIAVGSRSHFPEIDTMPLDELSDAMSFTASELPRLDKKVSCTMTEIYYYPFERDDARNGLHDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPP3</accession>
    <name>A0A8K1CPP3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_004205</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPP3"/>
    <dbReference type="OrthoDB" id="34781at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW66440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="182" mass="20788" checksum="BCDC31C94DB3597B" modified="2022-08-03" version="1">MGMAFSRVFERLFGKQEMRILMVGLDAAGKTTILYKLKLGEVVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYYQNTQGLIFVVDSNDRDRVDAARDELHRMLNEDELRDSILLVFANKQDLPNAMSAAEMTDKLGLHGLRHGRQWFIQACCATTGDGLYEGLDWLSATLQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ11</accession>
    <name>A0A8K1CQ11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial 3-ketoacyl-coa thiolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ11"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF107">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="7">
        <location>
            <begin position="275"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="41362" checksum="915253293D246D5F" modified="2022-08-03" version="1">MSAVAKNIYIVAAKRTPFGNFGGKLKDVSATDLCVHASKAAIAAAKLDPALIDMVQVGNVSQTSADGAYIARHVQLKSGMPIENPALTINRLCGSGFQSVVGGVQEILVGDAEIALCGGAENMSMAPLSVFGNKARFGVGLGAGINLQDTLWSALTDSYSNTPMGITAENLAEKYGITREQCDEFALRSQTLWAKANEAGHFDAELAPIEVKAGRKVEEFKADESPRITTLEKLATLKPVFKKDGVVTAGNASGISDGAGAVILASEDAVKKHNLTPLARIVSYQVSGVDPTIMGIGPSPAIRGALARAGLKINDIDIFDINEAFAAQWLACVKDLDLNPDLVNQCGGAISLGHPLGASGSRITAHLTHALQRTGKKYAVGSACIGGGQGIALVLENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQE3</accession>
    <name>A0A8K1CQE3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014127</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQE3"/>
    <dbReference type="OrthoDB" id="167591at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="776"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="839" mass="97857" checksum="F808BE67D512203C" modified="2022-08-03" version="1">MEPATNEQLMQQMVALIARQQEMLEKMQREQVRTEFKLEGVKLPTYSGRVEESAQLFYEQADQYFAAKGIAWKSVELAPRVLAALGGSLRGAAAQWFATRRVLIQSVDEFFTELHREFVPADLQQRLRDQLNALQQRDCRDLADYIAKHRQLMVQVRDMSEIDKVIYFQRGLKQRTREEVQYRRCETLSDAITVALDYDRAHQWQYRSEPRRYEEPRPSYLRNEHSQRAEPEPMEIDNVQRLSREDCRRRKLCFKCKKPGHSWRQCGSSKRSEPRRNQRRPVNNVEEDAVSEDEVILFDRVTTCNVQEKEETELIRKPAVIEGKPVTVLLDGGSNVNLIRPGLAKKVLGTRHVQLEAFDGSLQSQEVKKVQADVSMEGHVFKDQNFTEWNKMSEKHDVILGKPWHYEFQPNVNWRTNEVSFPINTEMAEATATNVVIDSVIDGDEFTQQMKKGVYEEVYKVKICAVVAKAAPDFVQPVLEEFSDVFPDTLPDELPPERSVNFELQMKEDAEPKSKGIYRLSKTEQDALEDFIQEKLRKGWIEVSNSPWVSNIFGVPKKDPATNTIPKRAEWLRSGNTKIPIRWVIDYRYVNSQTRVPQIPLPLIDELFDKMQGCSIFTVIDLAQGYHQIQEIPLVEYAKRFVDERKKLVELARKNLLAAQERQKQYYDKKRREVEFAEGDLVLLDTKNLPLRVAAEGAEEKKSKLAARRIGPFRIIKMINDNVAKLELPANLSRLHPTFNVELLTHYVPNPDKFETRPTSKAAPIIIDEETGEKTYVIEKLLEFRQVRRRREWLVKWEGYPEHECTWEPEKDLKHVSHWADLVEDFENRQREVKSGGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH9</accession>
    <name>A0A8K1CRH9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRH9"/>
    <dbReference type="OrthoDB" id="78053at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="965" mass="106598" checksum="5A91E707248B83A0" modified="2022-08-03" version="1">MAEGYSDEEFDDVEYAAEFEDDEQEEKPEADARDTANDEPVHRPKVDDADTVEMTSYEDAEHYDGDFDESVVIEADASDKDQKETEPVVAIENEPLQVANDVYESLSSLDKPPDDTETETKELEPEPVAPADTRTEQLVPEPVIPQVVVPRSVEEPTFRSPAMVKMPLLQRIGSLPRRATYGEVEVDPHPISFALKLRSSSVPLIDVPSDPDAPLLVRQSRSPRRRPATVARLSSVGELTPAELDEEELSESPGKELLEEAARVVAASSASESTDDTGAVRTRPFFPRLPSVSEAEPVLIFDEAATIRLAEGDEGDEEEEQEEEKEENPTTERLGKEEAIVGTDQRGKEGEESEEEELDSEALTAIQAIHEAAGKLCEEALEEEGEMDEEDSEDPDDAIYVSDPVPITPIHVDEVDDEPTAEPPHPAPDPVGNALKGKDAIEEEEEAVYEEEEEVPDAVHIEREVASEHETESLLHEAQLLLQAQDQPMPYDDDDAFMDDDFDEDNEREVAYDEQHDTDDIENYPADQKLDVSRPLETPIRVNASSDADQDTNAATVTRGASTGTTAGGTAEADEHASAKPTKSAQEATPKPLVTPGRVRKAATERPIAAAQPKRMTRPLPQERSTRAASQPTPPASTPKAPVPRQVRPVRTPSQQSEQPLAQPLTQRQPRATSPTPRAASFPPVEKPMTAPSPTKTRSQSPIKSTAGSPPPSPSAWPLPRKAPVYKQKKPSKTSESDNKKRLKPVKCPPTLRIELPHVDKEKREWLMLNMFRYGDDTTKYEPFIPQYVPTGSSPPMATTSHISEHVVVISEDATLPKRPLSARQIYGEGPQTVGFRESFTTKIYSRRGRKLVQHVVNPVHQARERNWVGTKPNDSSIPKYDAILDKFCKTVTSPVVQRQIYETRYDDLSPQLAMVLEKRAFKEWKHGSKDAFGAVSNSYKTQIVPLHGSGSSTTLLQPKPPSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS68</accession>
    <name>A0A8K1CS68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS68"/>
    <dbReference type="OrthoDB" id="128131at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="21528" checksum="9D8ED5F9477B3372" modified="2022-08-03" version="1">MRVRARELPKDRVLVVVALSCSLLLLSGVMLHSHEDASTSARTFRDGFIVANAQRRTESTSSAPPSIGGGLRGASTQLEVENGTHLTKIKTEDGDEITIKRGANSNKITKISAHEDGMITIENREHTPDDNHEGDMKDRHDDSEDTVRGASDTEPLSTGYEKLSADREIAGDRRIEPRPEENDTEQIVVETGVKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTL0</accession>
    <name>A0A8K1CTL0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005903</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTL0"/>
    <dbReference type="OrthoDB" id="268027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015">
        <property type="entry name" value="PROTEIN AD-016-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="29"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="816"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="163"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="843" mass="93595" checksum="029080FE6409C5B2" modified="2022-08-03" version="1">MVDSDSDDELLTRLTSTVFGRTSHVHEDCAYCATPSATLPCTTCNAAHYCNETCKRRHFAAHRRFCINTRMRNEASEEEAESSEEESDSEVEDVQPASRRGSGMMNAGSRTSRARGSMKMSSVVNEAMAASAKIQIPGLTQKQVKKLLALSAKAESMTDSKTIDDLQRQITELMAQRDADAAEKLSKLQRSESNSTTEKLNEIKELQRKLLELEQKTQTIEITTRNSTFHGGNTIRASKPVVYTPLLVKDDDVFRKYFKLKDMSMPIEQIKAKMEADGVDPNVLDNPDDVSPNDPGAPEGAYIPLLVKDDPKLKKYFKLKNMDMPLDQIRLKMEADGVDPSLLDHPAKVSPNDPGPPLYVDSSAFQDPHDLRMSMPVMGYGGMGSPSGGSDYRMSIPMMPTGMFPLMGAPPTSPTALPPYVPLLIKDDPDFKKFFKLRQMGMPDDQIKLKMSAEGLDPTVLDRPDDVSPNDKGPPAVDTAGSVPTPPMSMEHLFSILMQHQQIIQQVTSGGGGNMRANYAHSNGAGEVSAVAPKSVEDQMAQELAAAESALDDIFGEEQQSKGLGGGMSMIEQLEKKARKESNKKLVEHRDEINKVVQSVLTTTFETDVQAIAYYKEVAPQLENLGLTLGVDAVQTWSARLLIKNKDTRDWYFSESERLDAGKAYGRLWSMSFLERDAGQLIAKRTQILHAPETLRASVKNKPELIDKFTQLLKDTVKLKHKIFKSALYPGELRRLQENRLPERFEDRGTELIDATTVLSDAVLDLAEEEFRTLDQTTRAKKIRAHTAVVVAEKAIQLVGIVKKLGARGVNESRMSQVESKMQQLKDEYLSGEQEEEDEDDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTR9</accession>
    <name>A0A8K1CTR9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ethylmalonyl-CoA decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Enoyl-CoA hydratase domain-containing protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Methylmalonyl-CoA decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_005993</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer. Also has methylmalonyl-CoA decarboxylase activity at lower level.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2R)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:59540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:85316"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:59541"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:32131"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:60909"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:32132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(S)-methylmalonyl-CoA + H(+) = propanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:61340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57327"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:61341"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTR9"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004492">
        <property type="term" value="F:methyl/ethyl malonyl-CoA decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000109">
        <property type="entry name" value="Enoyl-CoA hydratase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF27">
        <property type="entry name" value="ETHYLMALONYL-COA DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW68525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="336" mass="36013" checksum="EF64E593F48CE1C4" modified="2022-08-03" version="1">MRAAQWGRNVRHGVAIQTSRYANGGRTRGYGLFSFVNELADDQERLVAKSKEVLRGLGRPDDENHVRLFLPGSTDASVQSKSILSALSQTAVIEVHNPRGRNALSGSMMAELADVVTILEDPAVQDKLSAVVLRGTAGWFCAGADLRVAKTELNSREGGTAMGALMMDTLTRFRRLPLVSVALIEGGAYGGGAELSTSCDFRVVADNAIIQFVQAKMGISPGWGGGTRLYKILGRQHALRLLCTAQKIKAADALSLGLADETFAYDGVKSADEAVVKFLQPFDSVTPEVSHGAKDVITAADDVSLDEVLEFEHRIFKTLWGGPANLKALENALGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU63</accession>
    <name>A0A8K1CU63_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU63"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="246" mass="26194" checksum="EDACABCF2684E64E" modified="2022-08-03" version="1">MSSTSSVDTGALFAAVFGGQLEELERLLGTGVQVENVVDVYGDSLLHAAASGGNVEVVRLILDSEGGMRLLDRPNNDGKTPLHYAYSANATAELLTRGADGNAVDNDLRTPLHLASLAGARDVVETLAKHGVELNNLDRYNRNAMHFAAGIKPEDQDVAILKLLLDGGASVSVQEGDITALHLATRSNWLEAANLLLDHGADVNVLDMDCRTVLLIAIQESFIDLVKLFVSYGAAVNKKEAARLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU85</accession>
    <name>A0A8K1CU85_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU85"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="571" mass="62018" checksum="C3706DDDD094175B" modified="2022-08-03" version="1">MMCGQQEKPRRLEVETGAQHSVCDLARIFSRLQGPLPLRDPVELEREQAHDTLVLEDHCGSGRVCTRVTAVDDERQVDAWFNFVVWFILFVEMTLVVWPAMTACAMAKKLSKVNWTLRTTTIKTKIASRVVAVKTSVVNYVCLTQLWLLWAMATLKKCEDASMVAWNSSCEAFADLVWSCGYVLWTSCPLVINQVKTQQLKVTEGDRVKCVSPKRAVVSYSDADTDSESEVEVDADADSTAVVLERALVDGSVCAHEVPPSNSLPREGRAAASMMLTLTPTPTMPLESVLVGTPTATVTPVVLVTSLSMTAVHVMKPSLVTAMDAIAVPMEPTTIVPSLQAVPVAQALPSTSTIPSLLSVAPVVSTLEATTSVAVEPSVLEPETEHEGESAPTPTPTPTPTPATLPVSSLTQEPAVSSSATQKCGLRRLHVVPISPQQSARPESDIRPSTPMAVPSATPRARVHTRADGASALSTSTLRKTASMPSPAPVRITPSTPTSVNTKRSFIRRLVKQKVKPLPIKRDVDSRYMRYAEEEGSSYLARLKESVLRRQRIQETYGTTNNVQTRAAWSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUE7</accession>
    <name>A0A8K1CUE7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUE7"/>
    <dbReference type="OrthoDB" id="71226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="582" mass="66740" checksum="86641D87BA481F97" modified="2022-08-03" version="1">MEVRDSDGLAGATERLDTLTMASEEQETLSRQECTMRATQSAQSGDYTTAIEWCSRALAVLGDSNEEKTRHAASVLYQRRSEYHMAVKDYQAALEDVDRALKLNDSDRRQTTKAYKAKCRAFLGLDRRDDALSTWTSHFGLDSSVLDTMAFERTFGLTNETDAEDHRYDTAIEYLYRRDYGNAVGVINKEMDRHNMVRKDPVWLLLRARCRLALQEFEQAAQDTERLIALFPTATEAYRWLCEAQIAQNQHNRAWKVCQAGLVVAPSNEKLLAIQKQLQARRAKKTKQKTPVNETEDVVEETDTVEEADEEAEDPRIVAIRALKKAIKAKPKDSSLYVSRARLRMELKQYESAQTDSEAAVKLNPDNVDGYISLCEALYALRKYPKGAKVSEEGLRRHPEDAFLQEWREKMEDAILEPPPFETDESDELPQQTRSRVPKVVAARRKERAERLVAEAEGLRIRCYDKAVDLADSRDFGNAVFWVNKAMGYAGKSEFAEYYTLRARCRFELKQFELVQTDCERAIALDPENPENYRWLSQTHKTLGRMDAALRVCEAGLKLSSDHKPLLSLQKILTQRNRQHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUF3</accession>
    <name>A0A8K1CUF3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUF3"/>
    <dbReference type="OrthoDB" id="59683at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="21169" checksum="39DA9333365552B4" modified="2022-08-03" version="1">MGSQLSLAVSTTMLIATLVYYYRMVLLTELTTEATLFNTLYAEYATPQMMDAIRSVEDFSHSLKVTETQIVCKKQGEQLWAKSFDHDWQRLLHWYQKLVYFHRLGLLSDRFYQEFPGPIRARHFVDHVEPFAVNSCKLYQDQNCSETFDYLRKLYGLPRRAEIVCEGEASTKKADATKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUL1</accession>
    <name>A0A8K1CUL1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUL1"/>
    <dbReference type="OrthoDB" id="160925at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="549" mass="60746" checksum="880FF59FC3C8EF09" modified="2022-08-03" version="1">MDNGRPSSPSTCTYAVLARRLPSAKSDGGDLLLAFSQDSLQVYARKTANTNCSCHQDTADPYTRYGFQCPHLESYDDYEPTASIPFTAAFQVLMTYRTTSASSIATRTKDLLLVCHDETALWIDFEHNLARGWFLEALTTALPAIPVDYVDLADSTLVLPDTVNLTSFILKSLSCLVKKEDFLRDALRHVIYEKIKLSLQIAQENDVHSGDEHAACHLLLSTAKYLAVGLDEPDLTAFAWLASGFINMLAMCASKKDLAVDQVTQSLEIARENSLTVLTSLALHCLADLHLQRGDDPLQATELLVEAARLAPPDSMEPAMKMQVHRKIHDLRAFIGMEKALTPTEDSDKTSPGKLVARKSRSAFSLWQHTFGERSTRSQKELLLSKVHKPADNSGGSCFVDAIGAQGARKARFRVFFDATHTFTWLQHEIRSRLEGLLVDSDNSVARPVRVEIFYDPQGKRVVTLMDTRLSEWVRSKDHTMHAKLGLTVLSTHHSATETPTTGPVVALSEAAHNALSSPDPRAIPVVTCSLCHQKIPLDDVEEHSETCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUP1</accession>
    <name>A0A8K1CUP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUP1"/>
    <dbReference type="OrthoDB" id="59899at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="82"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="32847" checksum="AE5A7DAE01DD6E49" modified="2022-08-03" version="1">MTVVDIVSDESNPLEERDQPFYDAVKKQFGDQCTEDLAIRVTRAFHHFKAHRMEVTLAEAKKILEWRAKLNADTILTRELDQSRTYFDCWPGMIYGEDNDGHLVAVDRVNEIDVDAFHKNFSSVETLLPHRLQYMERIQWEKAAISKRLGRRVYKHICIVDLKGLGLKHVSRSVINQLKPIFDIGQVYYPETLHRLYLINAPFIFHGAWKIISTFVEPETRAKIQVLKEGEKFLDIAQKHGIPLESIPACLGGKHPGRSMNSTFKPSVADTPLPVPTPSETPAPSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUZ2</accession>
    <name>A0A8K1CUZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUZ2"/>
    <dbReference type="OrthoDB" id="67021at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="58575" checksum="E6D90CE6D0CC81EF" modified="2022-08-03" version="1">MALSLGMSAVSYGTRILADKVCKAGVFSCSFGEAIQATTGTFPPDFSARTCAEYDGLYFDPQHNYAILVITALFAALMAFAIGGNDGANAWGTVIHSFAIRFQPAVILGTIFEVLGATTIGYGVSGSIQTGITKLQNPDCFACGYCNSSMTLYYMGMMAALISASIFILAATMLKMPVSTSHTIVSSVFGMTVVFGGFGCADFGFDNLGGVIASWFISPLAAGVITVIVYHFLQRFIFQARNPRERAYVIVPVLYFLVMFVIVMISYLKAPVLEHKPRWQGVAVGLAGGVLMMLIYLFMIFPRLRDNLPSLSSANRIGADVMDFDDVEQYTANNDDMDLKAVNGDGFLDAEVERPSLVLLDEYDALTPDQQDAMYLFKHLLVLVACLQSFSHGSNDTANATAALSAVINGFKHGINDCADPESPWWIMLIGGLFIGLGIWVIGQKVMDTIGKNISVVTFDRAFATEFSSAITVVVCSLLDVNVSTTHCQVGAVIFISMAAKESDMIQWKLVCFILLSWLLTLPLSAGLAALIAYVLKFSVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV53</accession>
    <name>A0A8K1CV53_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001618</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV53"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000001">
        <property type="entry name" value="Transcription factor BTF3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NAC-A/B" evidence="5">
        <location>
            <begin position="533"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="627"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="633"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="655" mass="72101" checksum="E15805DC556E8AE6" modified="2022-08-03" version="1">MNQDDFRRLLATGGGNGGERGSGGRRQVSENDIDFVRKLSSKKQKKITKKHASNAHEKEAYVPTQPGSQYRDRAAERREGRLVEEDEIPRFDVAPKKPSGGTLAPEQAIKGLDLSLLRQLKQEKERLTQAKQQLQAQVAKDEEELVFKSRMGRLVYYHACQNQPQASASTNSELFLPGRMYYTFNVKSDAYNSIPAITQRSKEDCPEVDEVVTGLVDDLVISSVSDALTQKRNIKKHRRKKGETVELAGTSTHVGQTQVETEEKAAFETEEPVAKEESDDEDIFADVGEYVPIYRRDDEEKKAAASGVSSNSGGGYFTNLSASLTAAEELERKKAEEAEQAWKATLKKAVAAQSQAEREKEQKARLAKAMAEEDTYSECFPEYQAGAGYDSDDDEEGEGKKKRKGGDGKSGATGEVDGNEQQRRKKQKHSNKLDNDLQKINKLMDTKSSPIRRQYTRTKCKPCIRGIHDPDLLTIQDAWELLAGERMGLILSETMADEIALARARLAAKFGDVRTGGKGTVRRKHKAAHKVTAADDKKLNATLKKLGVTPIPGVEEVNLFKADGQVIHFASPKVQASISSNTYAVSGHSATKSLQELLPGIINQLGPDNLANLKQIAESYTAAQKAAKAAAGADDEDDDDVPDLVDNFEDVSQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWC1</accession>
    <name>A0A8K1CWC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001599</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWC1"/>
    <dbReference type="OrthoDB" id="6604018at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="81" mass="8895" checksum="8E6360936EF2AB9A" modified="2022-08-03" version="1">MAYPFPMETGWEKTKRRFKEEPLVPLGCLVTAGVLAGGLRSFVKAADQRTQQRFMRARVVAQGATVVALALGSVLAMKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWN2</accession>
    <name>A0A8K1CWN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001764</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWN2"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423665" description="subtilisin" evidence="10">
        <location>
            <begin position="23"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="174"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="458"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="528" mass="54981" checksum="995F410D8AAABA9B" modified="2022-08-03" version="1">MVFTKFAPLVAATALLATDASAAIVDPAVHRTLRQQGNVNLIVTMKKGTHEVLNAVHEASFTTRGDLIHDLVSRLQQHAEDSQVEVGALVAKEAAGEFTKAESFWISNQLFVEGASATFLERLTSLSSVAEVREERRFKVPQVTVSTANSTVLANEWGVAKIQAPEVWAAGNTGKGVIVSAIDTGVRGTHTALKGNYRGAYGWFDPEAKKADPYDNNGHGSHTMGTIAGANGIGVAPGATWIACKGCRTEDCPESDLLSCAQFITCPTDTSGANADCSKAPHVVSNSWGGGQADTWYKASVDAWRTAGIIPIFANGNEGPACTTSSSPGDYDNVIAVGATDSSDGLASFSSKGPSKTGLLKPEISAPGYNVRSSWNTGDSAYSTISGTSMATPHVSGVVALLLAAKPGLTYDQVKDALIKNVDTATLKAAGQTCGGTKDGVFPNNNFGYGRLNALKTVGASPVPSPSPSSPSPTTQTPAPTTKTPAPTTKTPAPTTPAPSTCGELGFLDCYFSDNCYWSWSQGECVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB43</accession>
    <name>A0A8K1FB43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="2 11">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_006890</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="2 11"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB43"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF0">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="13">
        <location>
            <begin position="73"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU271113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW56880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="43904" checksum="88830B3AE3F3E83C" modified="2022-08-03" version="1">MPRVKAPRNPHRLQRSPHALDGAIESGREERQAPNSLTAATTPYSRDESRVGKARSSKKSPSARPQTKSTDAFDIGAASPPDAVILREQRRLSGEMVGTNVSPVEQTLKTKRIGRPTRTPKSIMTLEERLDRTEISEEMAAEIIEKLYEEQEKDDRDMYDITTQTVKEETKCELSSIVEELDVMEFRRLLTYGEVSVESVSSTLLPFLNLQADDVFYDLGCGTGKIVIQVALQTPCMVSKGIELMQNRVMEGAKAMQRLENLGIHMLSDKEINVVQGDILKPPAGADMMDATVVFINNVCFGPELMLKVMGMLSSMPKLRRVVTLRKFCERHRPQKCVRANNYCVEYVHPPDEAEIKVSWASKTSLYLYERVESSLANLAEQLQVPVQVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBP4</accession>
    <name>A0A8K1FBP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">urease</fullName>
            <ecNumber evidence="2">3.5.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_006351</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="8">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1708534at2759"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035550">
        <property type="term" value="C:urease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00375">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00407">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00390">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.280.10:FF:000001">
        <property type="entry name" value="Urease subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.150.10">
        <property type="entry name" value="Urease, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.280.10">
        <property type="entry name" value="Urease, gamma-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050112">
        <property type="entry name" value="Urease_alpha_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017950">
        <property type="entry name" value="Urease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002019">
        <property type="entry name" value="Urease_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036461">
        <property type="entry name" value="Urease_betasu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002026">
        <property type="entry name" value="Urease_gamma/gamma-beta_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036463">
        <property type="entry name" value="Urease_gamma_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009671">
        <property type="entry name" value="PRK13192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009686">
        <property type="entry name" value="PRK13207.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009712">
        <property type="entry name" value="PRK13241.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00192">
        <property type="entry name" value="urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00193">
        <property type="entry name" value="urease_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440:SF1">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00699">
        <property type="entry name" value="Urease_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00547">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51278">
        <property type="entry name" value="Urease, beta-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54111">
        <property type="entry name" value="Urease, gamma-subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="12">
        <location>
            <begin position="398"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="965"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="1231"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="8">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="8">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW56341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1319" mass="143060" checksum="6B7FFC72C42EEFF6" modified="2022-08-03" version="1">MRLSPREEDHLLLHTAGVLAQKRLARGLRLNYTEAVALLATQVLEFIRDGKSVAELMTLGTQLLGRRHVLDGVAEILDEVQVEGTFPDGTKLVTIHHPIATMDGNLSLALYGSFLPIPSLDRFPAPEAMVSTPGDVITPDEDIVLNGDRQVAALQITNLSDRPIQVGSHYHLIETNPYLEMDRKRAYGYRLNIPSGTAVRFEPGDQKTVSIVPIGGKKVITGGNNLASGVVDPAKVDAIVAKAVEQGFHHKAMEDAVAQSLGSALKLCRMPRSVYAQTYGPTTGDVVRLGDMDLYIAVEKDFTVYGDECKFGGGKVLREGMGQASGLFAHQVLDTIITNALVIDYTGIYKADIGIKNGLISGIGKGGNPDVMEGVMPNMIVGVNTEVIAGEGLILTAGGFDAHVHFICPQLCTEALASGLTTLVGGGTGPATGTNATTCTPGPNHMRLMLQATDSVPMNIGLTGKGNTSLPEGLQDIIDAGAVGMKLHEDWGTTPAAIDTCLTVAENNDVQVTIHTDTLNESCCVEHTIAAFKGRTIHTYHSEGAGGGHAPDIITVCGELNVLPSSTNPTRPYTRNTIDEHVDMLMVCHHLDKNIAEDVAFAESRIRGETIAAEDLLHDMGAISIISSDSQAMGRIGEVVTRTWQTADKMKKLRGLLPEDAASPFQRDNFRVKRYVAKYTINPAIAHGMSHLIGSIETNKLADLCLWNPAFFGSKPEMIIKGGAIVYAQMGDPNASIPTPQPVKMRPMFGACGAAVGPTSVAFVSRSCVEKKVAEGYGLKKRIEAVKRCRGVTKNDMKLNDALPKIQVDPETYKVKADGGRARVFPTADLSRAKRNLRHRSHALTNLNAPTHSLGLRAQPGGPMWQELFHDGSPAGASASAAVGKQALIAELVTHTNFTTEHIFHMSRKFKEIAGAAKNVITFQEFRQIMGDDVGAMLEGIGVTTLEFQELATTDMTAISATISASESFLRRLFLMFDGDGDGKIDFREFVVGLNAFIKGSLEDKVETLFALYRADDQQYGNKPPEANEPQGEPTIAISELLGLFQGDRQLYQELMRCVDEYFARGEVREENVITEDEFVAASLAEPWLLDAITQPHPSSLYREDAGLRDALRIFVTQQQLSWHKMLELHRRMLSIATTALVSSVETLAVYLPAIQVRQVVVDCVRPPRTEQEDADDDALLQQIFRAYVSASSGSSSSDSPATVALISWREFLQDLAVAVQSALTLAADTDSDAKAQYFFELYDLDRDGVLSRTELVSAVCAGFAHFGPHMTEVVRVLEDEDRDHDGELTKTEYLRAARRSSLILASLYTCLRESPSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC79</accession>
    <name>A0A8K1FC79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC79"/>
    <dbReference type="OrthoDB" id="119547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="312" mass="33994" checksum="5C1CE3AA2E0BA3FA" modified="2022-08-03" version="1">MEFSTLPASRTSSPMAIPTDAYHHHHHHHHQPHQHPHQQALPPLAFHSISPPNTAMRHTDARLPSMPKCCRLLGCANFAKIHGYCPEHYQTTPEAHAQMMPPRRFECSMANVLSSVSDRPMMPPQPVLPSFDALRLSVLTPPTMRRFSDPSAHSPATASHSVHPMATASPPRHFSRLRAHSAASMNRHSPASSPSSTTTTGSSKAFVKCRRENCSNVARRKGLCMEHGGRHFCKMEGCQKCAHRGGYCIAHGGGRRCAVENCTKSAQSGGVCYSHGGGKRCATDGCTHAARSGGFCIKHGKMVRQGNEQELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC94</accession>
    <name>A0A8K1FC94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable pectate lyase F</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_010486</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC94"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479243" description="Probable pectate lyase F" evidence="12">
        <location>
            <begin position="22"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="28841" checksum="E660BCEC42D2EE3C" modified="2022-08-03" version="1">MVQLTNVLCAALIAAPALVSGAALPTGSWPASKGTVQLTAPQVVKAGTTFDGGMKTYERKGVTCTSQAEGGKADAVFLVEPGATLKNVIIGKNQIEGVHCEQHDCTIQNVWWDDVCEDALSIKNGKASSVSRVLGGGARYADDKIIQQNGPGKVVIDGFYAQDFGKLYRSCGNCKTQYKRHVEVSNVLAVNPKKAVTMINTNLGDTATISNLHVQSSKGDKTVCVWSKGVTKGEPSETGYGPSKSCIYTAKDVFLNEKGYNFSDLKRSLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCU2</accession>
    <name>A0A8K1FCU2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCU2"/>
    <dbReference type="OrthoDB" id="161703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052942">
        <property type="entry name" value="LPS_cholinephosphotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43404">
        <property type="entry name" value="LIPOPOLYSACCHARIDE CHOLINEPHOSPHOTRANSFERASE LICD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43404:SF1">
        <property type="entry name" value="MNN4P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="207" mass="23542" checksum="FD0C062EC0E3B60D" modified="2022-08-03" version="1">MSKTHVEPKYYREDACFTQVEIVDVIKDLISITTETFAAHNITYFLDSGTLLGAFRDVHVISHDVDADLGIDARGLEYLQHNYVAFPEAYELNIWNSYLDPNSTRGNKLPVRIVHKASGLYVDVFAFLEWYGTGKVGPLTSWCWGNCVSCPQTSPNGKTLRVPRNWIYPLIPCLFEGITRKCPGQTETYLRYLYGDDFLTPKEDSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDB5</accession>
    <name>A0A8K1FDB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDB5"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000753">
        <property type="entry name" value="CAMK/CAMKL protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="31688" checksum="CAC7B2D9796BE962" modified="2022-08-03" version="1">MHRFHIKRKISDTLLGATYECERVRDFSLSDVKPTYMSSVAIKCCSLTIAEDATVPKERLIDHPHREEQVITKLITSGGHRNVLQCYDHFVADDMVYFVSEYCAGGDLYQHLSTFPNGTMDEATAMQTLTQIADGVVYLHSLGFAHRDLSLENVLLRHGEWKIADFGLSTQVNEWTSDCAGKDYYMAPEVVAQESYDPAKADVWSLGIMLFMMLTGSQLLPLASPKTKGFSVVVSFGIGAILTAWGMREYVSDAVVGLLERMLQVDPVARMSMAEVVASLSALAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD3</accession>
    <name>A0A8K1FDD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD3"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472688" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="368"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="689" mass="77212" checksum="B9AFA9F904EA28E6" modified="2022-08-03" version="1">MRSFLSILLLLVATFMASHPAHAAVHYAVTHLFLVGGAARDVTSELCHQATPPALAVGVNWRHDSDDMVIQLCQQRQRVEEIDPSQLVFQHIAVYDAPVCPTAMELFFVVHDDRVVCVRRVLASEVLTSGNYISDVWVSTQLHYNTDAVGWRTIPESVQVPAESLLRSFWNSIWQSSYHGAFISYQRPVVPVREVRILPDANADFLKTACVTWFSAHWEDTGAGYLGHGSHNKGELCMRRAFDSENTPVLLEVAVTRGASGCSSRFSQTETLDHGVHLCFRWGEATATEAPIVGIFLESLLVGKTPQPTLPGGYLLVSSTSLNIGHRAVFIYVSRGLIKDLPYSEPLNRPPLVAKKVAENDVTTKLTFKILQLADLHYTGDPTTECKDAPSEIGSKACSEAIMTKFVNELLDFEKPDFVAFSGDNVETFKSSLRQEAMDAATAGVEARGIPHSMIFGNHDDVHGFSRESLMEMAMKKKHSYTQRGPLGVYGVGNYELNVQAPVDGLWGVAGSDVFRMYFLDSNAYPVHGWLRSEDTKYDWIRPNQVEYYRQMSAAHDDNRVPAIMFFHIPLPEYGMDVADQRTGQHREDVLSSEVHSDLFSTLVELDEVKATFAGHDHVNEYCYKRESVQLCYGGGAGFGVAYGMKEVQRRARVIEWSVNTENKREIRTWKRVFGRLDERLDDQLLYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDR4</accession>
    <name>A0A8K1FDR4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADPH-dependent FMN reductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDR4"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014063">
        <property type="entry name" value="Arsenate-R_ArsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02690">
        <property type="entry name" value="resist_ArsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43590">
        <property type="entry name" value="ARSENIC RESISTANCE PROTEIN ARSH (AFU_ORTHOLOGUE AFUA_5G15030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43590:SF1">
        <property type="entry name" value="ARSENIC RESISTANCE PROTEIN ARSH (AFU_ORTHOLOGUE AFUA_5G15030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="2">
        <location>
            <begin position="70"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="32433" checksum="DE787E0A6E076963" modified="2022-08-03" version="1">MLRYTRRFSLLSRRLSSMASAPVTASSENLAKWRPHVVAADSADWVRDLADDLVGAKTFVVPGATKTHAPRILVLYGSLRETSFSRFLAYECARILDLLGADVRVFNPSGLPVRDPSIESTDPKVLELRSLVLWSEGHVWVSPEMHGQITGVMKNQIDWIPLNTGSVRPTQGKTTAVLQVNGGSQSFNAVNTLRVLSRWMRMPCSTNQSSVPMAWKEFDEHGRMKPSDYRSRVVDVMEEFYKFTWLMREHADFLVDRYSERKEKEAKGRLLTQAEKEAEKDAAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEF0</accession>
    <name>A0A8K1FEF0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEF0"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF23">
        <property type="entry name" value="NUCLEOTIDE-DIPHOSPHO-SUGAR TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="39500" checksum="665512C53832A422" modified="2022-08-03" version="1">MGVAKNEPMTQQRRVSLGLIFVGLLFICVGRVAMVGPHLMALNQPNHTNGLRAQFASMNALQLDRYSREQARIPWLIHQSWKSVDKIPARFEPWMRSWRELNPQWQYVFWTDDDNLAIFEHVYPQYLYIAKALSKIALADMARYALLHHFGGLYADADFECVQPFGGLHEEYELFLSSEPRAHAVLLEGSDSPALCNALMASAPGHPFWVQVLESIKAKFDTESESDPVSLTGPRIVKSTYYGGFENDTRVAVLPPTYFYPEIAYWNRGNLLEKCKDRNDTAGKEVCAWLEQYPDGEFTEKTHATHHWQCTWCRGAGDETVTLSSIFPTSVYRPSFNQSNNGPKLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEG7</accession>
    <name>A0A8K1FEG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEG7"/>
    <dbReference type="OrthoDB" id="75652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="329" mass="37061" checksum="8F30B411878F3363" modified="2022-08-03" version="1">MVLSYMRRAAQRSVRASVGSRGLTSSSAVSTETRFSAVRPPAASVASLFSTQSQTRLAQTTPKYVANDVTGILAGVAVVGALIGVGKMWWDASSSPSDGVSGYKRYAKQEISRDDLAQFFTDLKASVQQLFKQLPEIDSAFREHLKTNNIELTEEGYKQSLLQQLFDVLQNIEQQVVASRGWDPESFALAMEKFEQDEVIAQLQLELQELMQSVFPPPEIPEHLTPETTLTIFRELIKGMEQAMKEMLSHARAEGITDATRAMEEFSQIYMDQVEQINFEQMKKHNVTTEVFNVALQKYHAENADFKKQVEKLYAEQAEVFKRMGLKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEH7</accession>
    <name>A0A8K1FEH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pectin acetylesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEH7"/>
    <dbReference type="OrthoDB" id="2015280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004963">
        <property type="entry name" value="PAE/NOTUM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562">
        <property type="entry name" value="NOTUM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562:SF83">
        <property type="entry name" value="PECTIN ACETYLESTERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03283">
        <property type="entry name" value="PAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035473185" description="Pectin acetylesterase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="48273" checksum="1D989FE8CBED5525" modified="2022-08-03" version="1">MLHKLVLAAAAALALTTVSAYRPGDEVCVVSPDNACPLEKLTPSTLDTSTLVYPGGKTRCAFDAFSTTNFTTNATYFFQVFPNQKKDTTKLMLYLQGGGACVDDDTCSFALQCGLGSSSTFTVNARAMSNGVLNRTDENNTFKDWNIVHVPYCTGDIHIGNLVKEPYEPIFASILGNNECLKQNKTAHHNGYENALSAFKWAAANYPKPEHIVLAGSSAGALGAQLFGKMISDLWKVEDNKIRYTIVADSYVGVVPEDKPASRIVDYFNSCTLDFGLSSDIEKKCDNASASVIDVIKPMIKATPFSDWLFIDSKADVVQRKFFELFDDGILGYPFTDLLPEDQFFGNMSTIIEAYKSASSRVSAFFVEGDHHVFLNLVNWYSTTSTSNQTLGAVMRDVLEGNYTRSSSSSSQAGSAGSVNAPAPSSATIPVVSSALILALFGVLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEL6</accession>
    <name>A0A8K1FEL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEL6"/>
    <dbReference type="OrthoDB" id="5954308at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36535:SF1">
        <property type="entry name" value="DUF1772 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36535">
        <property type="entry name" value="YALI0E30327P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18507" checksum="37389D017DEEB774" modified="2022-08-03" version="1">MVTTEALLEIAAAATSGLFVGGALYTSVVQQPAFLECATTNEFRAPYFSRAYAHAARLQSRLSIVSSVSAIAAGILLRESDSTNSKLWLASGSLMLTIIPYTIVRMLKLNFQLIDTANCIKQGDKWMEENFRRWGQLHHVRTGISMVAFTGMLVALSDSFPVEKTIVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF14</accession>
    <name>A0A8K1FF14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Presenilin</fullName>
            <ecNumber evidence="8">3.4.23.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The PAL motif is required for normal active site conformation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase A22A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF14"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070765">
        <property type="term" value="C:gamma-secretase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.100">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001108">
        <property type="entry name" value="Peptidase_A22A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042524">
        <property type="entry name" value="Presenilin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202">
        <property type="entry name" value="PRESENILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202:SF13">
        <property type="entry name" value="PRESENILIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01080">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01072">
        <property type="entry name" value="PRESENILIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="54516" checksum="AE1F17FA274A514E" modified="2022-08-03" version="1">MGNTRSSNRRSVHAWSAQDEPCAWLGYQEPFLDASSKAETMITRRNGQTSKLANLTTEEVAALPEIDLPATIHQLNSFFAVLWPVCLTMLLTSFAACNVVDEAMTTAMKTYMYYQETPSSSMAEKSVLAFCNALFVIGFIACLTFAIVLLYKFECMRFFLGYCVFYSATLLGMAGSKIAVLVLGELQSTVDAVSLVFVMYNFAIVGVLSIFYQHGFPTAFEQGYLVCISVIVAWQLAQLPEWSSWMLLLLLGFWDLFAVLTPLGPLRWLVQLVQEKGTPLPGLLFQADIAAAHTDNTSAETTREGDDNFLSSLVADLQPPVAVASGANPFVPVEIERFAHQIAEFLADQQSAGVARSTELSERFVYRQHELWCHLYAYYGTAFVSPAKSYPAVFTTAPAPSPADSEADNSIKLGLGDFIFYSVLVARAARHDFAAFTACFLCVLLGLAITMHLLARYEALPALPISIFAGILAFLLVILLVNPFLHQLTAFGIFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF92</accession>
    <name>A0A8K1FF92_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">50S ribosomal protein L24, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_006573</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF92"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="257"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00035361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="709" mass="79366" checksum="B814D313E637A0D2" modified="2022-08-03" version="1">MEETTPTPRKREEDGDELCRTTPAAESVASKDAEKPAEQDTSPSSPRVNKTLFLDDSDSDDDKQDGEEAKEEEKENRCGPSSRTTYRTRSRRLSRLSEQLKNGNDKDELTTPVKQAVQRRHHSRVGAAAGGLFDSPLPTEKRSNSVRAKAPFPGLYSPVPSIKSPPSRRTSGAHQLSDIDMSANMSECSPWDSPPRRSSREDMMLSTPFKSPPPPTPMKNNVSTPSRQQFLSKKEILVHVQHPSDPEGAASMPIEELETVGWLGAGVSAEVLKVYSQRNKEHFAVKKTKHQLRSERERDMLLQEIVIIEHLAASGASFDHIVRYYRAWQMDGFLFVQTELCEGGNLRDFLTLREGSSIPEDCLWSIIHDIAQGLEVVHSNQTIHLDIKPDNIFITREGVLKIGDFGMAHEFSKPSNRDADQEGDAVYMAKELLSSQERLPSADIFCLGIMMLELATAVELPTSGEEWHALREGQLPALPAEYSGDLSALIAHMMHPDPSSRPTASSILAHSQVRNRGSPSQLILQHARRHRPAARRLSMPSPASFAQTPRKRRLSISDIISFLCEVKMKFNSAVSSSRRKSRKAHFGSHSTARRVLMSAPLSKELQKKYNVRSLPIRKDDEVTIVRGSFKNREGRVTTVYRKKFVIHVERVVREKANGATVPIGIDASKVVITKIKLDKDRKKILERKNRATDDKGKFTEADVQMANVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFN3</accession>
    <name>A0A8K1FFN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFN3"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052710">
        <property type="entry name" value="CAAX_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36435:SF1">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36435">
        <property type="entry name" value="SLR1288 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429406" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="3">
        <location>
            <begin position="180"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="34668" checksum="6138DF6BA0822D1D" modified="2022-08-03" version="1">MTDRRKMRHGWKWLGAPSSGVLGLFAASTSAASDAADAPQSNEDSEASNEANAAIPAAVQAVLLVIEIVMAFGVGLFCIWCATIARTIAAAVTRAVANEAIAVGVSELVHVLVFHYGVVSFMALLFHQHRRVLIIRLGLTQSPPVTVICMSLVVHSVYLLHLGLKVETLRQDLVQISLSDVLQRLLLAPIEEELFFRGLVFHLALNRLRGNALLAGAVASTSFALVHLVNARKLGPHESFDDLMVQTAWAWVVGLFLSLRFALKGSLLECVVLHVINNVAANVLGAMQLTLVQSAVSVADRVNQPSAVKLQGDRHTNFFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFX7</accession>
    <name>A0A8K1FFX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009653</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFX7"/>
    <dbReference type="OrthoDB" id="6344460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="608"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="682"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="625"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="876"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="845"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="932"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="113087" checksum="B5CA449373576C46" modified="2022-08-03" version="1">MARHVSAWDLRHLSGKYPWLRVDNETVEEFRAPFEWVEAASESASSEEELETDDERGKDGVPKRQHSHSGRYSLANPTNRRAASVIKAKPSRKGQFSPKKLSEKSGNSVQTPPIAPQKHSGTSHTTDAMIPPPKSVLEASVYSDWAALRQHQHETRRNPKKPTHSILSLSLPSLHRNPQVASKTSLASQLTRLAQQERSLQQQVYSQIEAEKAKLPLTFLFERHLDQSYCRQKSVETITTIFAKLQFRLVYSAFQRWKALNDALNKQELQEAALERAKIRALALLDRLASDCYVGTLDRAFGRWRNTIKAMAEHERQSAARKIQCIFRQRRAKALFHELKRASMDRAYKRDVEIQQLLRFERRMAQRHRDERQRMEELVQQSALLIQKRARGMEARRVTTLLARAMRLVEQQQRRRYAYSTQRNVNTSPLLAFLSSDYHQTQPDLLEQMIQDADAELISEDRAVVLLQRHFRGYATRLGFVVLQTQQRERKKLEERMCHLLQRVARGYLARKRVRQLKQKQRSEALMAAYVRERHSKSQQEAWEERYKQEQMTLQLQRLQVLETMRVDAKRDAEVAKWQAEAALYRKQELQAQLEAQKLQDTLKHDAWELVTDAKGQPYYYNTISGESSWERPSSPPKPLSKEEKTDEKPTEDGVLSAKPDETAHDSALLSSHLNLAMHFRLGAALCAECQQVLALRQCVGCDEALCAQCFETIHEASQKKQSHEFTQLELMKEELTSARDAYCIDCTLRKCTRLCNLCGDGFCSGCFDKQHSIGQRALHTWIPWTQFTQYDDWLVIHDDQTGKDVYFNIETKESTHTKPFVLQSGEDRHRALFHEREQPLKARALALEGEVTQLQDKLRIVEEEKAVLIQRPRSRVANASNAEAKPDQGKPRKGKLKSLFSRSKGKKATMAEGESTTTPEELAKQALKKGVTSSEQSLLQQKLMTRSRGEKEAKAQRTIGTKHFEDAMIQQLSTDPPSKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG50</accession>
    <name>A0A8K1FG50_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG50"/>
    <dbReference type="OrthoDB" id="101030at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="41202" checksum="C81287E5380A0C6A" modified="2022-08-03" version="1">MRELSLDFEEVRNPTTDEMLEAFLLVLEMNDRLLYLTLTVTDTQYDRFNERFLVFNGQYMRWKLPIQAKCAFLSVVKHAQRANAKTSGTKCRAVGNLDSLALSIILFMASERHLRSVILDSLTEQGGVDFCEQLRALELPLTPDEGDEDEEATWFRHCEAVELLLLASLVDPKGFTEMVWGHCANKEEIPRECFGYNPVMPCRLRLVISTFNDIERVFAKTKTLLTPRSTHSDKFNTTLTTLLRMGEEKQLDLEEAVIPVTIALSFLDERHANHLLSLLVEYQRTKNTHSDHLKDCRFVMDDVELDISGVSISGGLIDVVELFKSTPGLRFRTINLPLFQPHYDLTAAIYERRRIPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGI5</accession>
    <name>A0A8K1FGI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005423</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGI5"/>
    <dbReference type="OrthoDB" id="163057at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="27"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="175"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="416" mass="46703" checksum="F0BC3F7FBCF59475" modified="2022-08-03" version="1">MLLRSADVPKRANQHDEKPEEGARQWYIMGKVVGTGTFGRVHAARHRVSDDRVAIKSYFRDKGALVCCPAPSCIPKKPSHLTDPLEWKRVRREATLMATLPVHPGLVQLVEVFETPTQLQLVMECVDGGSLYDLLKRQPHQKLTEAHAKRLFAQLCAALAALHAQNIIHRDLKLENILLDEHARPRIIDFGFSQIESTRSDGRDAVASAVKNFCGTPSYMAPEVVSCKRYDGKRVDVWSLGVLLYVLLCGKFPFQGQSIHQLYQNIRATSLAFPSSLSKDVQHLLQGILVVDPAQRFTLSEIQDHSWLHTMFQSEILAQEHAFTALMAWQEAHDVLRTALDLPKDETNDTKGSKPRKGGSALVFLLLLRVEKQFFAQFVKKTASTQSIQLPTAPVTSITHKQQLEQLIGLVRSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGM6</accession>
    <name>A0A8K1FGM6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGM6"/>
    <dbReference type="OrthoDB" id="76910at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="505" mass="58315" checksum="6A4726D7D8721861" modified="2022-08-03" version="1">MQKGSQLGSSWTPPADALSNGASDAREDSVYRSLSASISTAASPTTIVTHSANGDGLSVLQLKIRALEKYKVNYELLCGQLAELNTQIGLQLQRHDVDVATLHQTVVSLQTANASLERDLKDCQAQLTTQKALNEQDRSYSNRVHTQLATVAELLKAAEKRFEEQEAQWLSEKSEMQRTLRGLQQEDGGLKQVYAQRTHELEVVRTQTTTIQEELVRCKRKHRSEVKELHTEINKLKEELEAQRATSRQLKKHHREAREERDVLRKQLGHVKSDGSHLNEVLETQRIELQRQEKKLQQWRVKSHDTERQLRDALQEVEEVQTQLLSANEELVRKNAQVESLRLEARIINQSKSHSSAESESSKTDEIKLLKQQIQQLKQQNQLHEQQVQERVKQEELDAMETQRRYRMELHQMRHLLTLNHQCASESSKDMKVLKEELSSVQELLRRQRQYTTQYQRHQHEHSDFREETRTPLPARADIEKAVLQSAIMEQVRALAPSPPHTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHX8</accession>
    <name>A0A8K1FHX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAM50A/XAP5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHX8"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="198"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="40856" checksum="69AD48BCBF1F0ED1" modified="2022-08-03" version="1">MASNIERYGSSGVHTVEGNLAGGRAARLTKQREKEQHEFARKKQDIQHNLQRGTRIDQNFESHRDEDEAEFKRQTVGLVTAEEFRRKRENLHQQNDVEAAADDNAALPSQKPKKATKKRKEKKLGPLSFDLDQDDGGMQLNDDDNLRPSTKKKKPKIMKDPTVETDFLPDKERERQEEEERKRLRLEWEQEQERIKNENVTVTYSYWDGSGHRREITIPKKTTISKFLDLVRQQLVTEFTELRGVSSDNLIYVKEDLIIPQNYSFYDLIVTKARGKSGPLFHFDVHEDVRLINDARVEKDESHPGKVVERHWYEKNKHIFPASRWEMYDPSVKRDKYTIHGDEVSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI04</accession>
    <name>A0A8K1FI04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orn/DAP/Arg decarboxylase 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI04"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43727">
        <property type="entry name" value="DIAMINOPIMELATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43727:SF3">
        <property type="entry name" value="GROUP IV DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="4">
        <location>
            <begin position="807"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1226" mass="136504" checksum="CBF6EFFA3424EAEE" modified="2022-08-03" version="1">MAAAAKAKSDGVTRKASPPSTPALSPSTLVANTMCDDVDREMEVTKDAGQRSASSSPSRRIALAQQVETFHPELLPLLKHYTVPEQNHHKFDLESIVDAVKLSSFLQDRLLCLPELNRNSPCYSARSIVLLYTKIRYLETFKPEEIAMYAATGDHEYEEVRLLHQLKNVASNAELYSRLATLLHIPTHGDMWNEITRFVACALPFAEQTETLLIRGSDERSVLSPITKTNKYNGSTIPFQCHIARASCTCSGMTLEGFTRCDKLRQELLLNSFSINPNSRTSTDYFDAKMTDVRTRVASCLGLEDLVEGDNMRVVLTPSGTDAELLATSAALARLFSGLELVGGKRKVTSIISAHGEIGRGSSSASGGKHFSELTPSGEPATPNEPLRRYPTDLVDVIEIPGRNADGSINRIDEEVCQTVADILEKGEGANVVLLHVVMGSKTGYICPSLEVVDRLAVKYPNRLIVVIDACQMRVERRLFREFVSKGYVVLVTGSKFFGGAPFCGAVLLPMRCVYEMETTAVEEYAELCHPLGLEDYFSRYDFPDSMKHVRQRMGPFMNVGLLLRWESALANMEPYYAIEPCQIEEICRSYVFRCKNHLRANWNSIIEILCDPVPAVLSCAKPMDTIVSFKVWDEHTQEHLDAARLRDLHTLLSKDLSSVLPDESLAKKRCLLGQPVQLGKQSGGVLRIAMGADMVNTIFHRGQREGTTEYVIEDFVRDDDLIIRKIELILEHWDKLRQQYIEEQVVSAPIELPKPLSDWNFSVKKTQIARVVRKLCMDGVLDSQPQQPISPYDDPPNKLAVVYDLDAIDMAFQALLTSFPTHFDHRFAMKSCPLSFFIRRAIENDVGVECASIVEVQHALRLGCPPHKIVFDSPCKTRRDIVFAINAGVEINADNFDELQVIREHAEELFQSNFPECTPRFAGELPRIGLRVNPLLGAGTNECLSVSTVHSKFGIPLTCANRQKIIDFFRENPWMSGLHCHVGSQGCSLEMLARGATILCDLANEIDTAAGVSRVKVINIGGGLPSNYDSDDVSPTFAEYVEVLRKCAPQLFERTGRTILTEFGRSVSSKTGWTISEVEYIKRHEADVEILGPNGGPDDLRQTAIIHAGSDLFLRTCYRPELFPHRLSVYNSLGHSSTAPMCIQNVAGPLCFGGDVIGRRVPLPQMNRGDYVVIHDSGSNTMSLFSRHCSRPAPAVYGYRVQDDELSIELLKPAESPEDVMRFWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI09</accession>
    <name>A0A8K1FI09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI09"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="39873" checksum="92D0561062D3C61A" modified="2022-08-03" version="1">MSASVKARGGTAKERSVFVGNIPYDVTEEQLREIFSEVGSVLNFRLVTDRETGKPKGYGFCEYADGATALSAMRNLNGYEINGRNLRVDFADGGDKSGSSGEKTTSGVSGEVLITAIEGAISKFGPLKLYDMLVNLKEHARQRPEYTKSILNANPALTHAIVQCFKTLNIPIPAASETQPLLAAPPLLQTPGLLRAPQPGVLPPPQRSPLNAGPGGGGILGMAPPGAPPIMGAPPPAKAGGTRWSSRPGPLSAAGGPVPPHAPVIQSAPPLATPPVQQPLMPTPSVPASSTQRSRDPRRARDPRLAKRPAGPEPTMPDKRMKMDDQMGPGRDANEYNAIAELARDMTPEKLNMLPPNERQMLLSYMQQHGLNPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIR5</accession>
    <name>A0A8K1FIR5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIR5"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF25">
        <property type="entry name" value="SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="145"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="249" mass="25872" checksum="B5EEA128E16E0D3D" modified="2022-08-03" version="1">MASATQVFDVMGKAVGELGPSLVSKVKGTIKFDVTGASIWLVDLKNGNGKVTKSTPEEKADITITLSEANFLKLIDNKLNPQQAFMKGLVKIKGNMGLAMKLNVVTTATRDFIKKNGGGAAAAPAPAAAAPAPAAGGLKSAAIFQALEDAVKKEGPTLAKKVNGVIQFNITPGGAWNLDLKSASPLLTAGQKKADVTLTVSDDDFVAIATGKLNPQQAFMKGKLKLKGNMALAMKLNVVFNAIKPKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ46</accession>
    <name>A0A8K1FJ46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011411</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ46"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="59236" checksum="734F9C496152495A" modified="2022-08-03" version="1">MGPSGCGKTTLLDILADRVHTGQIEGAIEVNGLMRDEKSFRAITSYVAQEVSLLGSFSVLETLQMAAKLSLPSSVNSFMIAERVADVIDEMGLRSCQDTIVGDLFRKGLSGGQKSRLAIAIELLSNPSILLLDEPTSGLDSSATYNVMKFIAKLCDEGKTVICSIHQPSSLVYEMFTTVAVLSGGRTMYFGPRSEAMKNFASAGYECPMYANPAEFYIELVNTDFQDHADISHLQSVYAASSTYTKLRDKIMADRNSAVGNKERIELVLPSASRQFMVLLHRNTLNNIRNPGIYWVRVFMYFMLCFMVGTMYLSNNDDLTEDDLVPALFYVQAFLVFMSVAVLPFFIEQRAVFIRERVNSNLSVASYVFANFIAALPGIFFIALISTLLVVLLADLNGFWWFLLNLFLSLVVAESLMHVIASAVSHYIIGIALGAGFFGMCMLCEGFMVPRESIPNYWIWGYYMAFHTYSFESFVFEHFSRETTPASAAILARLGMEDVDTPQNMAILGGYVVLFQLIFTLMLYMFHTGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL3</accession>
    <name>A0A8K1FJL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_000895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJL3"/>
    <dbReference type="OrthoDB" id="7392499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418909" description="Alkaline phosphatase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW60853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="513" mass="56298" checksum="9C8494300BA02AE5" modified="2022-08-03" version="1">MVKLFTFVVAAIAIILPAAQAGKTFEYKTLDYDYAFDEDAEAPRSMIMMIPDGTGPNIFTMARTVLDPSLKTRLHIDPLLMGQVQTHSSTSYITDSASSATAYSTGFKTYDRGIGVDHFKQPLGTILEAAKARGMITGMVVTSRVTHATPASFASHVVERDNEAEIARQYVNNKNLDFLLGGGGKFFTDAMLSDLSANGYTVVKNYGQLMDYKNQNEASGKLRVFGLFHRSHMSYEVDRLREQNSNQQGQNDREPSLPEMVDTILSILKNNPVAQKKGFFMMIEGSRVDHAGHSNDPGTMAKEAIAFDETVGVVKDFLNTHPNTGLISAADHGTGGITLGRDGTYAWDPEAMQKQVMSTEWMYNKLTDVLSKDCASATNETCKAKLLETSTALLTSNTNVTAPTEADTTVLVKEIATAVDKTRDLNNVMIELGHVISKPALIGWTTIGHVGTDVDLHCMGPSVLERMCKGLHENTYINKIMANYLNLAHGLEVETLRLRNFTTLEHEPDASHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJQ7</accession>
    <name>A0A8K1FJQ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Activating molecule in BECN1-regulated autophagy protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJQ7"/>
    <dbReference type="OrthoDB" id="6363363at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="148"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="671"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="367"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="681"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="729" mass="80852" checksum="3CA95000CF662510" modified="2022-08-03" version="1">MVRRLPLDVAASDRGDSHASIHAALVAQVDLEDKICQRALADLNPPGVPNSFRRRAIPRENNIAWILNKRERGGARISRAYGSDREEQYWAESESTGKHESQYFDLPPTTKSTISIAISPDGKTFASTHGDHTVKIICMQTGRILQTLVGHPRTPWSVKFHPTDPRYVASGCLGFQVRFWDIETGRCLYVSTLRHAIISISFHPSGDILAIASGTCVYTWDYQHTCPRIALFSYQTLRSVTFLPDPTKIMVGEANERYMQRPIGQNGQSHPADLTVTLTLWDFDPSWALSPQPSENTKAMNNSREILSHALIYNDGGFDISRCGRYLAICADFSLRQAEKDSEMEAASDVQQILSTAPQDPAADEPSNQTEHQSESSTTTSSSSLHSSLSTDSATSTSEPLDMSTSTDSLPLGPLTLNPTSRVVPQPSRLFPTPPFQFETQNMFAVLQSAAAGDPSLNVDHYLNSHVRRVRPRLHPSVNLHRTQPVGSSGAAPVRTSPINTAPAPPQRFSSQIRPNIAVSRNRYSRFQRTQRSRLAAQIQSTWLALISLDPQELGRVVQTCHLEETTAGGVTSVKLSPTSAYVLLGYGVRDRGPRESDMPVHRVTRIYRWENMELCSHVESELDDVNIALFSPICGGGFLYGTKQGKLRVCSTYRGRFEDHENCNMLRVSSDPRPVYHISDDEDDELDDEIDDEDVEDDDMDGLDDGEDDDRSERADVRANAGEAVAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKV7</accession>
    <name>A0A8K1FKV7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKV7"/>
    <dbReference type="OrthoDB" id="27267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="748" mass="85152" checksum="AA7D0F97848ECDF2" modified="2022-08-03" version="1">MTRVLASSDAPTSTHDDDEDPQEHTSLDSLNQQPLVSKYKDTIRSASLTVRLAFRPFLACWLSILLFHVVTAVILLQYARFYRFLSNPQIGYYVRLVDVSIDQTFFLVIAMVYRVLSALNVIEVVRMLWFSFVFRRPVLPPWSGVAALKEESVRASLMSTVRLPRRRPVSRNSHIVVRVLYVVNQMVTAVFSERGLLGIKGRFFNWLQTLRKIVQILMLMYQANQVSQLVTQLWINNYYVVAIIFNCVSTPLIFGFVRRQEGLLRVLCLVCDIVSGVFTAVVLPYSLYRSYASVWDGELMGFGDEYLYDDVWFVNGILENRMIISTTWVHLLVRVYPFLEWLLCLDSIKILVRERPSLLIRRLVFNPCRSLPSLFATRSPSEPMLMRAPGKPPVLQRQKRRYAIWMPTIRPDRAVRQVRRRVHSVFLLFAILTGLFSGISHIPSASVPGCKATVKPWFTLTPSCAVLEINCYRHRFSGNASSIKQVMKAFRPTSTISIIFAHCPELEISSEIQSLSNVIGVEIYNSTLVKWSQDAAMSHRHHTTLTFIAIVLTKLQSMPEGLLTEPIPSLMDVELSFTNLSALPRNMHVFWPKLSTLTVEHSRLTEIPESVQLLTQVTGLAFTDNHIQSMPSALFDDMTYLGDLYLSWNPYTDLSMSLGPRNPSLSSVMVGHTNISTLPSYFLDADVLNGLDEFSIDSTPLCLNVKAHQSDYAPDLYAVLSSCKEHTKDSRIKDSYYPVSVVMPHRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLU4</accession>
    <name>A0A8K1FLU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLU4"/>
    <dbReference type="OrthoDB" id="1883418at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34211">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34211:SF3">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="710"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="765"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="791"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="908"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="359"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1056" mass="121240" checksum="8E440945B3A1E23C" modified="2022-08-03" version="1">MEKTGEDNDQLVWFALYGVLYVSFYFFTSPFVGNPELLTTWTPYVYISMGLYGWLFAAAALHTPLHQLGLLESTIKQPITLLFPFFSVSFAILVILELLMVQLIPRVTSCLGVARRPENVSFLRSFANVLRNSAAISVACVALIIHCDPTDETEEESQSYNHHACDRLFLYSRANVQFVPESYRGALVIWIVGVALAMTNFVLEQMSGIKVINIHWIFDRGEVDAEESEGEEHLHETLPHEHRLPMVPWYSMFLFDTAFQLLISLKVFLGRFDHRSLQRALYPDDDAFYFDHLASKNELWLDFMADCGDGFNSSYQIARLLAQPELEVECPEELLNPAQSSSKNSKRKSKKQTVKKVFPRGDTLLIGGDLAYPHPDSESYEQRLWRCFEYAMKPPRDYDPEAISTNKPYLPEGCEKLSDYKGPTVFAIPGNHDWFDGLNTFTRFIAHRDWLGGWLLPQKTSHFCLKLPHNWWVLGVDLALENDINTEQFSIFERLAEKHMGDNDTVIIVTHEPRWILDPYEQSEKTEEKLTYLINNVLKGRVVLRLAGDIHNYTRHSLKHVDMVSEVAPVLPGTPPRARSPQRTRSSSLMRRRHSMPAVPLQQRTLSPTRKHFPHMYEEDNESEGQVEEVLTRRGSGVWNTSLDAPPVGGAHHLIVAGGGGAFLHPTHAPQIKNVQYRGSTYKQRKCYPPEHVSRRYTLLNVMGFRRINWRFDIVGGLGYFLLVFSMFPRCSVHAIHTSATWQEAAMQFAWELLEVQHEMLTSSYVSFVTYVMMLATVTAFADFTSLWKKCITGLLVSFSHCLAAFSILLIFECIFEVAIERGSLGHEGDNSLYRYFTASLPDFSDVQVYDVLNVTQLFAEFMKFCMTIFDVPEMVAVNRIKICSSEAGLAGLSRTEMWRYYFSVLPYFWVLATPVVGVIFGAYLYIALNVFGRHYNEAFSALRIASYKNMLRMHVHPNGDLEVFAFGVDKMPRKWRRDPHWSGGSHVKTENKLPSYEWKRPSYWLPVVSRVSNMLRMDFENRELDGRLNMSDRSTVHLIDRVLIRRPAVVPATQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM25</accession>
    <name>A0A8K1FM25_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM25"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF297">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE-RELATED PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="385"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="945" mass="105179" checksum="BE776EE900E31D50" modified="2022-08-03" version="1">MRGRAFTQIEDPSIVPSLPIYAVSAPLSPPRASGKTVEIRRLVSPTRPGGATRQAVVSPSGSMAASAGRTVTSSATPSPKRDAITSPPTATRPPPAPAATRPRTDSEVRKMQRVSQWKEEAARLSMRVKELEKENQSLRRTVTIPPTSLADGELEGLLAALSEAETPSRAQSNGIPKSKSFANGFGQAGLTVAEAAAASHRSRSKRMGKEPLQKYKSGYWNEQNKMKTSFSLNNLAEMEQTALSFEKPRPTFQLQRSNSTTSRSVPKPNLDGAALIRTASRMSDSFNRSSLDQTGEEMAAQHKQQLAIAHSFHGTDVTQASPPMRSYQDTDIDEMSDEEWEVEEEEISVTSPRSYFEASLRGIGGSFRLPDRSKSLAVTKRPSTSDVRIWVGTWNMGAADPFVDRGGIMDEQRSGTMLQNFVPHGYHVYVLGVQEGVSENVYHAVAAYLNRNEGGTRYFRMELKNSDFMVLNKSHPTEATIDAVRGRGDGAFVGTKFTGLAVFYASSVQDKVQLLRAGVHKFNLTSGSKGGVAVALMINQTSMVFVNCHLDARNDGYRREQIRTLNANLGKVMGHQSFDLTEQFHHVVWMGDMNYRIVHLDPDIVLHMLEEGRNAELHDKFDGLLNDRRNGGIFDGFTEPNKFPDFYPTYKKFPKRGNVNHSLPSWTRLVYRVLYKEPFYKGGKVKKRVPGWCDRILIHSLLVSDSKLMPEKVQSPFDESGGWIDNYRSVNDGDGMDVSDHSPVYGTFVLSFPQHSESMSSMSPRLVRRNSRSMSTASVRSTPTPPRSSNVGGSYFDQPHVVRRIAAHVPNRSVSTVLRVFNMQLYWNDKLVVPKRTRVVAPLIGEDLKQCDVIGERCQGLNGLNLSLNAVVQHSRPLEHLHMLVWVKNDSITGHCTLSLKRVARQEEGGEVKFRVPLYNNSMRLYYDGHPLVLVFSVRSKTFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMG0</accession>
    <name>A0A8K1FMG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMG0"/>
    <dbReference type="OrthoDB" id="79470at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="295" mass="32493" checksum="7E15A941E41BE75F" modified="2022-08-03" version="1">MLEETPVVPIARMPSMSTDDDTPTVRGEVRRSKDFSTMTPGVDLLALLASESMDADEESDEPLSPLAEKSSQHTPRQETGVVESTLASETTRDEAKSPVEKGAENVSQESDLVECTHVTPRPPPAEPVGEEASTPTSVETRPVQTPPPATPTLTHPSKASSELSAETRQLVYEFLYTKVLRADIAGCMNTPMTSQLDVQLCQVAENQCGSHAREIHDFLYAHLTDAQRLHHLPHLLNDLTRAFHAEAQARHEDVSLETQSSICLIENMFLALGRKSPLQDMYTAEEEEMLEELAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMW4</accession>
    <name>A0A8K1FMW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMW4"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000093">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="81"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="50095" checksum="1F2C2CB3AA1D1EC3" modified="2022-08-03" version="1">MMMTDMEKPGPFNAPRHRVPRASTHTASRGSGVLRAPLFLAVVALFGLGIGYHVYNFSVGLPQYAPLHEPFYNKTMVEFTTPMGAFTVELFPEHAPKTVETFLKLIDSGYYTDRAGFYRNEPKFLLQGGGYLYDKVSPFPNLPVEYSLPSEERNLVIARSHKSDSGNAEFAIMLHDNTEHNKPTEDSPGYTAFGRVVQGWHTIETISRKMRDGYLAKEDRDRQVVFEKVEYVSRITNDNHEAKKRLEELNYVLETKHTVNILSELDCAETKELKALFTKMKATVRVEEVGYSLAHPYEHEAIEALSGTTKLPLVYINHKLIGGLTEVKALQDTQRLSGLLARGGTQAEDTVWTAIHQYPLVIFSKSYCPYCKKAKEILASLGAQPKVFELDLREDGAAIQDFLLSFTGQGTVPNVFIKAKSIGGSDKTAAMYKSGELKDRLKRAGAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN76</accession>
    <name>A0A8K1FN76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN76"/>
    <dbReference type="OrthoDB" id="58355at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="41122" checksum="0B1FD88C219D343C" modified="2022-08-03" version="1">MEVSGAMLALLLFVTIAIPLLYVVITWEHGIVNRYPVLPAPSDLGTKEFRWRCYLSSWTRRGWKKAILRSPCPRLTLQSRFALLSTDFAKLTTSLGFKELKLETIPCIFPQVAVSGLMLQLLGNSNFPAALTGLRLKAVTICQLRPLDMRFRDEPIAETSNAQEEEQAMEGLNCVMVLTEKRILEDEIEFLIQTDIFDDQGTVWQSTTCLAVPFYQKTLLVPLSVTAAQLDATLCDKSYDKLETNAFACSTHHLEEFEDVNVTNLDGTATDKRATPLLWALGRAMGVLQQTNRVPTLPLLCSFVCDDANDVVIPLQSRVECESSVATMAAGAEERLVTKVELKHDQRVVVSGFLRTVGWVFEEGATAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNN6</accession>
    <name>A0A8K1FNN6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">B9 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNN6"/>
    <dbReference type="OrthoDB" id="184109at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF2">
        <property type="entry name" value="B9 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="447" mass="49141" checksum="2407BD8984D93CCA" modified="2022-08-03" version="1">MLRKLASPKRASRFAASSEARGAQSKELRDLTVEAPSHEANSSDVSAPPSEPRSKMTLSFKKAAKKSKKTAGSGSDVDIPSANTKGESGGADPLTEAKTTDREKSPPPLLRTPRRRSIVGDDEKPGEMPGETPPLMRTPRNRSILDGEEMKVASPEKTDGKEKKKRESTQLKKIGKSKGKRDNNEDKANGSSETTPSEEKMIKGDKEPTQRTRTSNEKDRSTISAPLSPIRRKPRSTDNNNSTTSAATIGSKPARRTTAVPPSNQPEVHIIGEISGGDGFGSGGFCCKWAIEYGKNWIHIAGDQLGQTQIDYPSSSGQDYDLVWAHPIDLHFAMATLQGWPKMLLQVWYVDTHMAMSLAGYGFIHIPYYPGHHELTVSMWRPMGSAKEELEAQLLGHTPELISDEVLFTTAWAERCRLKTIATGRVHLDISIIVRNVPTHRMELNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNX8</accession>
    <name>A0A8K1FNX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acid phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNX8"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43428">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43428:SF1">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="6">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="158" mass="18270" checksum="DF7A5334679FF1B8" modified="2022-08-03" version="1">MNVLFVCTSNTCRSPVAELFAVEWLKRRLGLSRAQQEEKGIRIHSAAITDAFDREGSPASAHAVSVMHQYNIDLSLHRSRLLTEQMCAEADYIVCVSMGHRDKVRELYPNIRTMKATLCTFERDVPDPWHMDYETYTENVAMMEEVVRDFMEKTFTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR18</accession>
    <name>A0A8K1FR18_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">sarcosine oxidasee (formaldehyde-forming)</fullName>
            <ecNumber evidence="3">1.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005990</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>sarcosine + O2 + H2O = formaldehyde + glycine + H2O2</text>
            <dbReference type="Rhea" id="RHEA:13313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57433"/>
            <dbReference type="EC" id="1.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.3.1" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR18"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000189">
        <property type="entry name" value="Monomeric sarcosine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008425">
        <property type="entry name" value="PRK11259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF7">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="8"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="401" mass="44198" checksum="80D18041147EF33C" modified="2022-08-03" version="1">MSSPSVYDVVVVGAGLMGSSAAYHATLRGKRVLLLEQFEFLHSQGSSHGPSRIFRVAYSDATYTKMCIDSLAMWRELEKLTGKKLLEMTGELDFTRERSTVIDEVAQVLKQCGEPYEVLTPAQVNERFPGFHLPETAHAVYSANAAILNPTLAMQLMQELAAKQGAELRDHARVVSLVQQPLNGEEEGIVVTLADWSVFHARQCIVTAGPWTKQLIASQPGGANIDLQPVATFGTYWKCDPAHEEVYAPSRFPVFINYDSPEVYGFPLHNRADGIKVCSHKGADVDPEKRQDVTTQPAHLLASVQDFIKSYMPHVDSNTSTRVDHCMYTMTKDEDFILDFVDAPHASNPSNKTKKQLVVGAGFSGHGSKMTPVIGKILADLAIDGQTTYSLDKFKLARLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTH0</accession>
    <name>A0A8K1FTH0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTH0"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="120" mass="13476" checksum="A67153E39B0475FC" modified="2022-08-03" version="1">MSAIGALRQLEKEKNKGGDENEGLKALFTNLPSRIRQSKPVKTTVAFAKKSWVTSSRWLWIFSTTMLITLVPLSIELLREEQTNEVVKELLGKGFTYHQIQGMGYHVSQPQSTLAEGTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Y9</accession>
    <name>A0A8K1C1Y9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Y9"/>
    <dbReference type="OrthoDB" id="154634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16015">
        <property type="entry name" value="LTA_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052701">
        <property type="entry name" value="GAG_Ulvan_Degrading_Sulfatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751">
        <property type="entry name" value="SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751:SF3">
        <property type="entry name" value="SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="394"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="944"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW54950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1016" mass="112570" checksum="27A20EEED2A05D44" modified="2022-08-03" version="1">MTARVVDLESHGVSALQTAAGSSCSPAWLWRLAFYAPSLLYPQLARALVVYRDGADVGGASVLKGAVFGGLQDAAVFLQTLVLVRSVLALQNACCCMETASRWRRLLVTTCTASVLAVAYLWMTLACVVDLSLLWSFLPRLNRGFVRMYLNFSSQFASSMAAVLTPRMLMGIALYLVSMALWVAAILGQHIKLPSFAFIFCQRSGQASTSSGPSSSSVQRGKRSSSALPSHSSSSASNSGLFGCLLQLCVMSGTFRTVFLALMVFVSALHSTIALDGDGNDIYLLSNAMFSLEMESFLRPPTRSNAAGLTFHPDVQTIQQHGDANSTMAPQLSPFLERTLGLNERLEFAEGGNLTGAYPLWRKTLGYTGEKRFDIRLKREMVSENSTETVVVPPTVILLNLESFRSREIGVIGGRIIKEEYNQTVTPFFDKLSRDGVLFREHYTPAVQTSRTLIASLFGSLPSLTDDSAVATFAETKLRLHGLTHILKQAYNYASAFWSAVNLTWEDWEGFLRAQGFDDLYDEDTILPFLSEKKRNDLTDDDRFSWGRHDDISFRALSRFLSKRNQQATVDPENTPPLFLDVYTVSSHDPWDLPSTFQPNTNYSMFITEDNEKYLNALNYVDQALERFITYLRTKGLMKNTILLLQGDHGYGRMEHGDNPTIVASRVYDEGTHVPLLVLADDLMPEEDKGRVIDDTTSQVDLLATITDMLEIKGFMQHGVGQSMMRQPISDAERAVVLENPFYGVTKGLKVGDRKYVRYGSGRYEVFNLKVDPEELFPVETGKATSGFHHNETKSAMHYLDQMLQLTQFMYETNGFVPSTVDEESLTTDTQSDGEHVEEAAEVNAAETTEVEGEQPKVDDEPAEGEATEEAPVEETQAEAEEPVVVPGDGEIVDAEQIEEHGETTELSETQHDEWPAETSIAEEAAWEDNAPEAEEIAMEVEAGISEESTTETPQDEQTVAAELESEPQDPVDPFVAEEKGFEEEMMEPSVPLGVEEEQRLAALEEQVEKTVDVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C294</accession>
    <name>A0A8K1C294_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C294"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="282" mass="29517" checksum="E07F3B597008F1A3" modified="2022-08-03" version="1">MSVLGSRLAGRVAVITGAGGGIGRKSALLFAKQGAAGVVCADLNEAAAAETALLIHEELQRLGKSDVVARPLKVDVSKAADCEKMIQLAEKEFGKVNVLFNNAGLMHSDDDDAIATQEDVWDLTMNVNVKGVFLGCKYGIPALRRAGGGSIINTASFVGIIGAATPQLAYTSSKGAVIAMTRELAVIHARENIRVNALCPGPLNTELLQKFLDNQAKKQRRLVHVPMGRFGEAAEMAKAALFLASDDASYVTGTKFVVDGGITAAYTTSEAEVDPFGGPSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2X1</accession>
    <name>A0A8K1C2X1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2X1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="35004" checksum="67DB81BEBBA531D3" modified="2022-08-03" version="1">MFRVFKKEEKPVIVANGEDPELEEFLRKEAEEEEQRKQKRRRRQGNGDDEPKLFMQLSWAEQRRAGTNAPVLRQVEGDSINQRIRVYRRSLFFQIHSKLDHNAYVLTQLRLNKQDPNGKDEKGRTALHYACRYGAEIAVRTLVYEEATIDDPDLEMRWTPLHYAVMGGHDRIVERLLEKAPVRRITINRKDKHGVTPLMLVLMVPVPRVLFSLFHPMMVFALGVWRGSSSHRKAPASQESVRRRNRSAANDSALVAEVLVQYDANLKSKTYTTNETALEMAERLRSHLVAILLYEVIYRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C317</accession>
    <name>A0A8K1C317_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C317"/>
    <dbReference type="OrthoDB" id="91810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="319" mass="35651" checksum="A08DA38A51F57C68" modified="2022-08-03" version="1">MANLPVFFFHGAGGNAANGIAFDQFATEQRPVISLNFAENEASLQPLPGQVQLAIEQIRNYTRNDSRFDNGYTFIGHSLGGIIARGVVEEMDDHNAHVLISLASPHTGLCHGPQADPNIAQQFGVVLLNSYSLPVEIFDFAKYSIDTIKEGHLLVDLMEVMEKHPEITQNSSISSLLRYPVRKIWLDLKPYLSTIGNLEQSCDEDKQRRKNNLLKLKEFHAFTSPQDGVLEPYQSGVFGHYTEVADSAELLAKFKTLGTVDMKDTVEYKEDTYGLRSLDKRGGLFRHVVDQVPHTCWVMDDGDCSVKKILETQLAPILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3B8</accession>
    <name>A0A8K1C3B8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010569</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3B8"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009466">
        <property type="entry name" value="PRK12826.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="25690" checksum="0C412B36AB1E08E9" modified="2022-08-03" version="1">MRVALVTGGSRGIGFAIAQQLHRTGWKVAITSREVERAAQAAERIVASGNDVVPFAYQAPMGFASDASNDAASLVAQVTKACGPIQALVNAAGISKDSLLVRLKDAELEELLLTNLVGPVQLSKAVAKSMMQQRKGAIVNIGSVVGSSGNTGQTAYSASKSGLIGVTRTLAKELGSRNVRVNLVEPGFISTDMTATMADAAKERVLSSVSLGRLGEADEVAKLVSFLVSDDASYITGQCIRVDGGLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3P5</accession>
    <name>A0A8K1C3P5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="241"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1203"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1345"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="1388"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1492"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1509"/>
            <end position="1539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1546" mass="173801" checksum="09F21F6DB583F9D4" modified="2022-08-03" version="1">MASASRATELRRRVENRRQAALTEAKCVEDEAEEHVEATDAMESPSTKSEASYTSSVRRTRLPAAMLPSLLSAKKDLYGIQMEVFESDARQLASIRCADQQFTVDKNVRRLKSDLHATQMSVRQKVDRLDDLQSRVLRLSRLLTDTRDESTFVRTKIGVDEDIRKEQVQPQLSTMNYNIQCVSPAANMLSPVAPNQFRLTHLTANQEYGKISIAAITKNGKSAPSNVVETVKLAPAVAPTEPLFVSVGTVTAKTITLSWIEPTDDGGVPIVDYEISFVEAIMEETITHDKNFLDVSEIVYKSRLVRTYSASTTFTVPDLLSGKEHKKFEIRAVNSAGIPGKFSTVIESIFTIAPGSEFKLLDELQAAVNARTRIVDSQFLSGFMQRYERHHYIDLVSRFILSIHPELESKVHTILHGNDPLADEEVESTAASSVFRRRWEDLSDEEINAERRRQFHFRIAELGRELARVDYNIQWCKDQRIHLVSLIRAAETRILEKQAELERARMFRGPQMDSDVLENGLQRFHTKELILALEDEIEIEQLYIVDAKSEIVKVENYFRADEKHRTTVLKRIKDRQSALASFELNPRAALNNSDTKKSTLVRLRDGLLYRTFAALVENRDACRDMRRKMRAAINRMIMCKTRHALLHWRANMKALAREQAMGDPNCAGVGTIGLVNAAIGRYELVSDTRSLLDQIRRTDSKLQQLAWTSEQVANMKAESASADTSHEEHHKFYPFWLEVEAKMDVADWEGGLRVLEFIQSNSGWVEGMSAQRVFDLQLKIGQAHFQMKKYDHALIAYNRASILASRCQNQLNEGTAMLHLGATHFAVGSLQQSIKHYEQALLSFEAANDARGEVACYRGLERVFTKLDDREMMTTNKKLAEEIEFALQNKLAGAGDQLQRLQQRLVGIGAESSKEIELERVGAIVTRLRRDRIKSKYRIREEHKRIASLEKLLREKKELLVQGEIDLKRALASDSTQVESNVINGSFARYEIEDFKHKLAKLMGGVKAGEEHIAKEIMNAKIRISNGEDEIKELESELVVETGALMRRMQSKERIRCFRFNATNEALKNVIGTASHGYTTCVASAGHNGLLFDLLSGACLSQALGDPHKEHLGDPTGHQAQIVSLFYFGHRIYTGSVDASLGVWSVKDEDIGGFSCVLQKLVTDFDSTVVSVTSDNEWVMCGSSDCDVFLFDAMKLTLIARIITAHSRSATALVVRSSKLSLTTGGADNRIKVWEVGPPSNSTTRRNVKLVHTLEAERKGDEYFNGHLHPITCMQQIASEIVSADSNGRIVIWNLEADTKLLRICNIHKVAVACLQFDAMKIVSGGADGSICVTDFATGHLLQTLVGHRDSILDLQFDRSRLISMSADGKVRLWYWQTRIGVGADRKKYHILGPGETLKSLSLRYRSSIEKLLKWNNIPDSSKLYLGQKLVVDIDTNGVASDELKTLDMAVSTQFGKLSYENLDFMAANKVQSTDVESQWAAQRLALLAKEYFPPLDDDNENESKKDEGESEEEDDSDEDSLMAVDTNEEPGENEGSESEETKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4A3</accession>
    <name>A0A8K1C4A3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008904</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4A3"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000016">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="75"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="55617" checksum="B380BD796B4D5B5F" modified="2022-08-03" version="1">MSMFLRRVLASGASKRAVHAPVRSFSHDAKRNAAFATWNADDKRFFEQLLRPEAVLTDLDDTASYTTDWLKKYKAHSAHQMVLKPKTTEQVSAILKYCNERGLPVVPQGGNTGLVGGSVPVHDEIVLSLGSMNNVLSFDEVSGILVCEAGCILENLDNYVAKHGYMMPLDLGAKGTCQIGGNVSTNAGGLRLLRYGSLHGTVLGVEAVLADGTVVDALSTMRKDNTGYDLKQLFIGSEGTLGVITKVSILTPPRSSSVNVALLGCEDFESVQKAFVEAKQHLGEVLSAVEFLDRQSLDMVLSQQDWTKDPLESSYPYYLLIETSGSNTEHDMEKLEAYLESAMTKGMVVDGTVAQDAVQARKLFMIREDITLALSQRGYVYKYDVSLPISQYYDIVKDTRDRLEEFGAKVVGYGHLGDCNLHLNVSTLEYDERVFQALEPFVFEWTSKYRGSISAEHGIGTHKPEYLHLSKEKNAINLMRQMKQMMDPKGILNPYKVLPETSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5M9</accession>
    <name>A0A8K1C5M9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5M9"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="33181" checksum="8BE8BEE593801387" modified="2022-08-03" version="1">MLLRRALGGPTRPLVHRHAVLVTRQVLATKHRWSTTARTAPLLRLVSGACELPHPQKRATGGEDAWFICSDTVGVADGVGGWARKGVDSGEYSRTLMNSAHSALVKLKPKDESAIPTPLEVLTYAHRRATCPGSSTACIVQLHDDSIRAINVGDSGFLLCRSSPSEEDPTKVKWQVVYESPHQSHYFNCPFQLGHQNGDLPEHGQLIELDIKQGDLIVLGTDGLFDNLFPEQIASLLDSALPTIEQDGESMEKVASCIAYTAHKSAKGTKSRTPFAVAARKAGYEYAGGKMDDITVVASLVTTSAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C677</accession>
    <name>A0A8K1C677_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Beach-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046851">
        <property type="entry name" value="NBCH_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031570">
        <property type="entry name" value="NBEA/BDCP_DUF4704"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF163">
        <property type="entry name" value="BEACH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15787">
        <property type="entry name" value="DUF4704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20426">
        <property type="entry name" value="NBCH_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH" evidence="4">
        <location>
            <begin position="2026"/>
            <end position="2320"/>
        </location>
    </feature>
    <feature type="domain" description="ELMO" evidence="5">
        <location>
            <begin position="2858"/>
            <end position="3019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1254"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1515"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1661"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1804"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3107"/>
            <end position="3162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1254"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1531"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1674"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1707"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1730"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1827"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1848"/>
            <end position="1878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3162" mass="347723" checksum="D998EE376D0E4134" modified="2022-08-03" version="1">MAMERRQSAFTAALDGIAEAPPTVPTDTTVTTFLQELLGGKEYREAEAVKLTIRNPNALKALFTTIVGALEESAQIQALDALINLVRSSCSNVEACSSYGLQRAVLTFLSERAFFADPFVSNAVLKKILRLFLYLSNHSVTSDDVRAMLSVFRSPRMKEEVPDDQAVSYYVSTLEMIARDSFGPVSFFDLSGEYSGLVLPVLDAFPSNGYTFCAWIKFECLPDTAAPLFTFCGKSDVGIMCSFIRSSLAVTCFDKKKNDSHVEIPDLITPGRWHFLCIVHTHRPIRGSKLDIYMNSELRHSTKLTYPNTALMAPVVKSYIAMRERDRGPSLRVLLGPTALFGQPLPSNIIGNVKSADEYDALVFQFNSYISSSTTAGPGAAVPTGSTGAPSTGAGEGLLFAYDARNCDRQRGLCFDSSGNGNHAEAASTGVRLRRTGTFKQSVAQLGGPLICLPLLVAASNATTVHSNVPVDSNGLALASPSGGSLISQFDEDSEFLQQMADMIARPLGVRTVSKVLLLIAEIMRHSLVNKFIFRRHQGVRLTALLIRSLPPRYLTADLLLSIERFRSAVISDRTLSDEIYKFLLFNFRIWINAPTDLQHTVFTKLEIATRRDAATSSAVSTRHFLRCLSWIYWKFPNPTALRRAREFSVEDIDALRRRVLSIIKLELCEAQPVKTSVIGRGAKAKEMKTQLSYESTKSLIFCMIGKPTNPMSSGLNADGTPSLQDAGEVGTTAKDIKSLSDGEADAGSVVENVPENDLPDLIELLIELSVQPTAPAGLLDLFGRLGGLRIWLPLLNFPSNVLRVMTLRLLRTYLTLKCQCVQDREKVTSTEKTQLSVGDSYLILNALNAAGHPVTLGVYTEVLLIVLGIQVTEEEMDAPVGSREDYDALVSEEMLAGAMIWHTYMMFPFLEMVRASSASIRLVAIRHLKILFASSTPASAINRNMLIYNSISSSGALTVSSTTEQTPIIEAILSLRGNSKKEERRELPHTLFGVELNGCPGVPMSRLRELVTSSEESEETRINALYSIISLDDVEFVSSLFAVHSEGERKKNSHGRVYKNMSKRLRVAAVEIMAHLQPEGCASFITQTAYELISSIISLEAKSNDVSWILLQDPFTSLSRFIDSPKELEMVVVSLLKATLDKMNELLSVEINLRGKDDIPSRDSVLWRNAENLATLSAAVVLHYDPDTLGGINPVTLDATEVQANLVYWKCDRLLWHEAELVDAILGVWQHLASYFHSEKDASFGRKPARSAGLSQRSIDNSGSQSPPANAALNGVAGKANSSRGLGFGFNLLAVQSGQAQGSVAMRPHPGGPMRQVLQLLLRSFYLILLSDDQPGDVFAKRARTMSGTMLEASAMFFARINKLEYFLNVMGLGRDMTQFESSFTPSRTSTANIGIGGLVTLSSHIKAAPGDETSLILWFVPELAVLISRVRRKLWPDSAVKLAGVLASLVSQPLRSSEELISLLAQSDFSSNNQEVCRRDGFYFEQMAHARESRATRRAAMLADEVEEKTRAKAELDRISRSTRNRQPSVAGESSASSDESGSQVWLQRVKAKDIDDWMRLRVLLKWGVRHVWTSSSSSDLTEDTSNSLSEALKNNEFWRLDNYTSSNWIRCRLLPDTDDTMADYAEYVKSMAVDSAEVAAAVSLEAISCQAADIIKPEDDRDIGESGAGVDDAEYEDEEENYDVEEVSGTVMEGMDGFGNEDSGSGGETSEGSRTPGGGATEEDQKTSPLSGSPTEPNGNLISSGEPLSSSQASPQGEKPAARPDNLVDTPDVTNSVKGSKDKFPRIGTISSRFSSGIRLITGTGARPSEKGEEGDVANADLSEVEKKEPSANESERQARRSRLESGSTETTSETTTDPNAASPASVAPASNTPSRILRGLSSRNEQWRTLSACYRTKAYLILPSGLMIYGILRIGTTTIVFEGEYVTTLKKLSDLADDSKVEVNLGDSFISELKRRVWGVRVIRVIHRRRFLLNPQNGIELYFVDGSSCFFGLEGRKEADLVYATLKERKPPCLAKWGKRLLSAERMFGKSKWTEMWMRREISNFEYLMLLNVSAGRSYNDLTQYPIFPWVIRDYESTQLRLDDPTVYRDLSKPIGVQSEVGQKRASNVFASSKADAKLPPYHFDTAYSHVRSVFYFLSRLAPITGAFAVDGLSVENFLAGGVFDSFSSAYAKATEEENHNYELTPEFFYLADFLVGDRNKQLVKGTEEGSSVAGLAGLRSPVQLPPWASSVHDFVRQHRLALESDYVSENLHHWIDLIFGHKQHGQPAIDAQNSYHIACHPERLDLRSLNVGSRARLTLRGSVPLQLFRKPHPARLSQDESLETRYPASNAVAALSSRRQVRRHDLASKHTAPVLSVRFASALNSTMGMGGPGLGSGTGLGAHASGSNDHGIVVYTTDSDGVVLAKRYLNSVPDQPKLCPFSLVDVDQWWKLPTGSLVRDGVVFYEQMISCGYWDGSWRIHWSADGELLQRIAFHKKPILCMAHSEDDFTGDLALAFGSEDCTVSVWALSKVAATRSRRMFVKKDLPIGGLPWVLLHGHTSPVVAVALKVDLDIVVSSAKDNTILVHSLRAAMPLHNIEISCAANSFVTHMTISNHGETLIHSITNRSPPKGRSHSFNVLNPVNHGSSNGEEQSDLYLVSVNGQLISHDRLEDAEGKARVLLEQAAFFTRSGEYIITATGGSESVIEVRDAGAPAAIVRRIDCKRSSILTCVSLSQDERCIMCGYADGSVVAYALHYGIADGCKNQLGLDKKARDEEAEALARANKRDQLKKEADEKKNLFKWGSAGATPSKGLWIRPGKIVMPPEPYLSVMQSYYSWLKQPCVGDDPTYEALVKELWCAMYDRDSLASESKVEEVNLLDLPDDLAQPAEGKEFERSGPTWSRLGFQRPDPTTDFRAGGIFSLKCLVYFAKTYYEQASRMVEHQIPGSRQNTYPWGLAGINITCMLSRVFWAGDGCLYKERHHNWPFFAEEDAFYQIFSEVFILFDHLWAEMDAHYGMFSEVIQATMRVVLDAMEEAKADLQAFLVEIRAQSLSNTSRFHKGRAASRSMEEFLVNMSSSLTPLDPSSVPAAPSSFVSVTATSFPSADADLLLSFDSPKRADPLEVETTTQESDEAAPPATADSAFDPFAGNDIRGMATDLSNAANEPATEDPFAMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6N4</accession>
    <name>A0A8K1C6N4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6N4"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000502">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="9">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="51610" checksum="98F7C5646C4F5780" modified="2022-08-03" version="1">MSHFVRQSKFRHVYVEPAKLEKCYTNLRLATATGEQNYIKGNSKFFAVSIQAGGGAMAVVPYEKVGKFDPDFPLISGHRGAILDFDFNPFHEHLVASASDDTTIKIWGIPEGGLTETCVEPLVDLQGHGRKVTLINFHPTANNVLGSTSSDFSVRLWDIEKGSEIVSMEPHGENLIQDLAWSWTGNTFGTTCKDRIVRLYDARSGQVAMQKEEAHQGTKSVKMTFLGDKETFVTVGFTRQSQRQFKVWDPRNLDKELKKVDIDQAAGVIMPFYDPDTNLLYLCGKGDGNIRYYEMSEGEPFAFPISEYRSTTAARGMAMIPKRACDIMSCETTRLLKLTSNAVEPLHVYVPRKSDAFQDDIYPDTYAGVPSMTADDWLEGADNSPALMSLRPDQFGKITFDGKRAKVPKQNNSRVARVARAFSGNTASSGGAPVKRADGTLQKELDAANARIAELEAKLRDAGISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7V7</accession>
    <name>A0A8K1C7V7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Seipin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7V7"/>
    <dbReference type="OrthoDB" id="3990054at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035423937" description="Seipin" evidence="8">
        <location>
            <begin position="21"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="44044" checksum="B24F73876F087D30" modified="2022-08-03" version="1">MKWPSLWNVALALLPAQLTGSMYEDDEARRETREEMVRALQSFSRSAAQWLLRLAQVLLGFSVLLVTATILYSVLYYLIIPSRLHEQEIFFDYGDHAALSLSPAARTAAPTLPTAYLNLLKPHHQWEFSPLVEMEPTDTRVLVPGVKYDVFVELEMPESQVNRDIGMFMLQTTLKSHDGEFLASSARSAIVKDSHSLVELVRVFSWLVPYALRVTEPSQTVRVLAVNGFKEGKQHPLTSVTLVLNHPAVQIYSARLTIIAQLAGVRYLMYHWSVSTAVLVILNFVFVEALGLLILYAYYNLPVPDTDDTRHKSPITTDQGKVFEQNRSGGIPPVHVERAMKEEPMETAELLNRASAGELLSALQEEEMQLRYRKSASEETMAAALAASLKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C804</accession>
    <name>A0A8K1C804_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C804"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="14167" checksum="2523AE82A5DC984B" modified="2022-08-03" version="1">MVKETKTRNTKRSPDVVARDCTINLHKRLHGRTFKKKASRAVSEIRKFAQKLMKTQDVRIDSKLNKFIWSQGVRNVPYRVRVRLSRKRNEDEDAKEKLYTLVQHVQVATFKGLQNETVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8U6</accession>
    <name>A0A8K1C8U6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8U6"/>
    <dbReference type="OrthoDB" id="93513at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="191"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="38657" checksum="B570FC60C63F9DFE" modified="2022-08-03" version="1">MGRFAHKLKIGVRGSLDVLLEQTSLKTGDVVSGSVRLVVDKPITTRGLNVTIAGRERLYWEHSDDSGPHPHRRALDLLDEKRTLIDPLTSPDEKVSVECCDREYPFNFELPSHLPATFEYKCRRIKGMERVRVYVEYFVTATLLVDGFLKADLECVIPITVDSTKLPRQLTPEPVTVTKHNDVKLFGLIRQGSVDVKMAISSNVLDPKSIIIATVDIDNSSKRELESLRLCLVEDICVDRHRKRFNRTRASYRDVCCRLYDKSLLGMINSDSRSMLKLHLPVTPNDIYEFGPLLPTMKSHFIVSLGYRVVLDCKFQLSQRVKIDIPVIVVPSTSRIVAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C928</accession>
    <name>A0A8K1C928_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TAZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009992</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C928"/>
    <dbReference type="OrthoDB" id="167934at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="5">
        <location>
            <begin position="441"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="347"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="732"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="733"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="765"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="779"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="794" mass="86429" checksum="5A176925DEC64EAC" modified="2022-08-03" version="1">MFDDMAWTDDQPHGDWEMELQRVRYGSEMGFRDPSAAMDDPFYLSNGSGGLAARATGVTSSAMASNGPTMTTLHPSSTLTTSASCPSFTSLYDINGDDLLSDIPDGEPLGELFMNPGFNPPNANANATAAMGGYDYVLQFQQQHQDGYTRQYPHQPAQISNEHLAAMHQSRRQLHMSASFTSLSSMETEYKRRLAKKRKPGYERPHKHQRHKSFDSTTTSVSTAMSPATSMEFTPFHTTSTFESTPEGRVLDGSTDPEMIGFSIDDFPSTFTSDSSWPTAPPPLSLAAGLPFDSINEAPHSENQRTAFASELHEKDNASTQSEMEMLFSENERVNVSKILDAIRDFDSPVEESESPKPARSSRPPPSKSRPPSARRKSRSPQLRPSIVNKTELKRSASSSSSTCVRERINSLLDANEAKPETSITLDATEQAFLAQSPLFAPEKTAETAGSLWLLLHSSQCQQACTIAGCDVMRRVIKHCRSCEAELGKCRDPCNEAKAMLLHYATCSLRSTKDDKQSCALCAKLEEIDRTHNAIKTQSVPSPQMMAMGMPVGAGPVLIAPQPTFVSPTHKPATGNSKHVPIQPNPLPTASNPMGLMGSFPQFSYSLALYLEQTSSAFRAEVKARVEKRVTAAAGQDLIQHMQKKTRLRSLDDIRSEARAIVLGEMERELHYHMQNMNWPSGSDAGAKVDLNESGLPSYLLSVAAAGFAAFYAQQATLQAAAMRMSTIPPFTLSSSAPSPQSLSRQSSTGGPSTPSVMSLAPRNVGSSVDASPTISPKETIKTVERSTKDLSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9S9</accession>
    <name>A0A8K1C9S9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Apoptosis-inducing factor 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007055</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>A + NADH + H(+) = AH2 + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:11356"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9S9"/>
    <dbReference type="OrthoDB" id="6029at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016174">
        <property type="term" value="F:NAD(P)H oxidase H2O2-forming activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012501">
        <property type="term" value="P:programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029324">
        <property type="entry name" value="AIF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050446">
        <property type="entry name" value="FAD-oxidoreductase/Apoptosis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557:SF4">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14721">
        <property type="entry name" value="AIF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01353">
        <property type="entry name" value="AIF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="12">
        <location>
            <begin position="85"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial apoptosis-inducing factor C-terminal" evidence="13">
        <location>
            <begin position="428"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="61520" checksum="3FEDD4405516250D" modified="2022-08-03" version="1">MWSLGRQATRAVSTLRRVKGTRRIGTSSVLLTAPLLALGTAAFALSGDEVHAQSESGRRVSPPLSKEHMRLARRFTRKNNQKFHRYVIVGCGTAAHAAIEAIRQGDPHADILILSDERALPRLESRRGGENDANFVNDALLETYNEWRRHITQKLEEDPTEPVVITGGGVLSPSPVTLLMKKNTTMHFDVEKNRILLSDGTEIQYEKCLIACSGRPRHFYVLDRERISYEIKDRINTCTTLHDFEQLDALSKRPDIKRVTIVGGGFLGTEVATALATDPRNAHLKTQLLFVEAAPGSRSLPSYLAKELARRLTSVGIDVVADRLVTSLKASTDGHDDCVAITAMGNGKHKLKSDYVVLASTHTEPNLRLDRQHCFEVDDKHGGIKVNAQLEAMAGVFVAGNAASYYDPYLGRRRVDRYDHAVNSGLLAGRNMVASGSTNHLKLYRHQPVFRSDLKGIDVQIEGIGEIDASFHTVGVWVQPTASKESPQTPAYERGVVYYLKGNKIMGILLWNAPDVMESARQFMLTRPEVHENVIDELKEAISLGPDDWLHVVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Z8</accession>
    <name>A0A8K1C9Z8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Z8"/>
    <dbReference type="OrthoDB" id="4096268at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000019">
        <property type="entry name" value="Nuclear inhibitor of protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="76"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="39266" checksum="95EA2FC89B888EB9" modified="2022-08-03" version="1">MSTTMELPPFELPKLNLGTTFPASRPKFLAPLEPPTFPFTAPAWMLPHEPRSIALLDVYKSHEQLATYTVDKKPLYLIGRNAVACDIVLNHCSISRLHAAIIHHKDGSTYLVDLGSFHGTFIDDMQLKALQPTLIVHGSVLKFGASSRSYSFRSFESREQIVEIVQSRIGLEPDEMELQQNTMMNRALSYRLGISIPVTHKLDAEGDDPMAPGSTRQIEEPSSAAALIRRTQSEDNSMVMGTFPIHPHINLVQMEQEERRKRSRTQSAGPLTGNNSTAPNGALQISVQNGSSPVNGAAPQQIGADVDPLKHVHFIERSPEVIPDCFARFLNADELSPLTLSTVNETPAAQESKNDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAI2</accession>
    <name>A0A8K1CAI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAI2"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="457"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="305"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW59479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="513" mass="57107" checksum="9278E37DA138AEAA" modified="2022-08-03" version="1">MRDKRVKKTKQQPTTQPALVCAKILHPSTSSRLSQHEIRILQRVRHPNVIHFFHAVSSPSQNAIVMEFCAGGDLRAFLRPQRRVDEARVWSWLVQLCLALQHLHDRVSLLHRDLKTANIFLNDAGFLVLGDFGVASTGNLATTAIGTPLYMAPEMWDNRPYDCACDLWALGCVLYEICMGRPPFEATSTPALVRKVCDGTFPPLPAGRWSTRLRELVGQLLSVDPTRRPRAAAILKQTESAIHLERYLLDRRAAAARLGSSGVEVEDGEQQILQTQLQRMGITITLEAPTPSQAKTEAIGGSVEKTEHQLTLEREQARQEQLRNALQRLHEMRQQQHEQNVEAKLKPTHDAVTGVAPLNVEQRPQAIEESLVWKPPAQSRPKSSRRASGGSAVVCPASSVAFSGIPRTGVPLTQQSKAFVASQKPVCRDVRDLRKKEAAKAARRYRLQLDEQFNASSSVKKALGRQNDKQNEPAAVDRDGFNTLDGNEPNEDDGVVESYLAELEALLRQRLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAV4</accession>
    <name>A0A8K1CAV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAV4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="12925" checksum="19BDDD3978AC0572" modified="2022-08-03" version="1">MKSKPHFAVALWSTSKGAMALTALMIVLNAAYMLAQPLLIKAIIAFVAGEENMFGADSGNGLALMLATTALVGTTFVNLSFYLTSRIGGSAQITMVNAVSQKILQSYRLKRGATSRRGRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBD2</accession>
    <name>A0A8K1CBD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBD2"/>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="20"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="29316" checksum="573A9E8003A095E3" modified="2022-08-03" version="1">MRGNSAQSMSSRSNQLDENDIQMQGWMRKQKDTLRSWPRRYFTLSGKVLTYFDSEDTSRPPRGVLEFADVSPLTTEHNGLILHLVGGKEVRMIADTHVAYTAWMAVLSASLRRPQAPKSSRMFKEGWAHCLTDEDVWTRYYLVVKNDSFSCYESEDESAELALSGLVRSVAEWDGKRYGLVLGLNRSRKIQLCFDSAEEKMTWFLTLEFSVSYGAARMKKEASSKSSSKSSSEANPARKSDPSASSESSKESAEDDGVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBI7</accession>
    <name>A0A8K1CBI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBI7"/>
    <dbReference type="OrthoDB" id="73842at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="46478" checksum="8C888B0130924B1B" modified="2022-08-03" version="1">MTMDALDESAAAAFVDALGPLTLDFELDAVAVDVDNTFAEPSASEATESASNSQEGSGSSAPSVGKNASRERLKAELAYLREKVESLEHDLNELQQREATSGTQAARPKAAVAKVWKRIATRQLERRQEAEAENDRLKAVLDAQICVAKSLEQMLRKRSSEAILDLYEGARGSKKRCRAEDDFNAVYAHLLEDIECAYSIVDQVFETNGLANVYDETIRGYTVKTRSTKVHEQAYIEFVDVAILPFAFERAMRAVWQSTADEYARDHRIILNSRRGADHFGVRYQIQKRGRASSQDRLDVTIIMRQYIESDRMVIVWRATNASSNSSHLYADETGWNVLKRVPTTGSDDTDEAVVMQSCVHLVPRWSDSDRSRQVDQIQTGDFTKLVVDFFEDDVSSITEAAENLLLDERVVSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ0</accession>
    <name>A0A8K1CBQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_004496</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBQ0"/>
    <dbReference type="OrthoDB" id="527990at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.132.10:FF:000001">
        <property type="entry name" value="leishmanolysin-like peptidase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.132.10">
        <property type="entry name" value="Leishmanolysin , domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.55.10">
        <property type="entry name" value="Leishmanolysin domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001577">
        <property type="entry name" value="Peptidase_M8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10942">
        <property type="entry name" value="LEISHMANOLYSIN-LIKE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10942:SF0">
        <property type="entry name" value="LEISHMANOLYSIN-LIKE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01457">
        <property type="entry name" value="Peptidase_M8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437611" description="EGF-like domain-containing protein" evidence="11">
        <location>
            <begin position="33"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="618"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601577-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601577-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW59427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="688" mass="74933" checksum="E4ECD828743450E1" modified="2022-08-03" version="1">MWICSQSPSDSVGGKLAMRWLVLLAFAHAVGGCIHDQIKHQVPTTNVQEYSDNHPFVMAEARRQRKLQGLSDDLSDNLLGTQDYDRVMGQEVDSSSYSPIRIVPYYDNTTLDLLTPEKRAIIFKILPDAIRRFQLTLSVVPVVGNLKAQRTCYVQWKTTPAVCKDVAPSERCLEMPMPDSHFTAMKTCSTCLATGCTVGDCSTTKEGTGVANADFMLYVRAANSSYCTGPVLAYASSCQKDQYDRPTFGMANFCPEQIKTDPRQYQSQLSTAMHEITHALGFSSLFFPYMRNSDGTPRTARNSDGRPPAQANVQCPNGQTASLYVAPSSNTVKFSSERDTSVARMVTPRVAAFVQSHFGCSSLTGAELENNEEGCLGSHWEERIFEPEYMTPISSFRNVLSPLTLAFFEDSGWYKANATMGERLIFGNKQGCAFATSKCIDKASGVSVASDHFCTSNDAESCSVDANSRSVCTISSGLSIPKPFQYFSDPSKGGINDYADYCPINTGFSYGDCSDPTNLVMPTGTTINILGETYCPTCKCTRTTLRSSDSKKWVVNARRKTGCYAMRCRDSSTVDIDIPVVGSTTQVVTRTCTQKGQILTVDGYSGSVTCPDPLIVCDRSCPGACSGNGVCDFGTAKCTCSNGWSGEDCSKNTATTTSNLRTDTASRMDQSVVTWLLLGLTSLMLVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBV3</accession>
    <name>A0A8K1CBV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="9">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBV3"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="10">
        <location>
            <begin position="5"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="37420" checksum="3F887A92E4BFF2D2" modified="2022-08-03" version="1">MKPFNLAVHLKYLVGLKDKKEDFESCMTEHMRVSGMYWGVGSMALLGHEEDMKPEEIIAWVLKCEHPEGGFAGNVGHDRHLLYTVHALLILAMLNAVDRIQVEKTAQYVASLQQPDGSFGGDEWLEIDTKFTYCALSSLAILKRLDLVDIPKAMAYIDTCRNFDGGYGNIPGCESHGGHIFTAVGALSLGKAVKQYVDADLLGWWLCERQCDSGGLNGRPEKQADVCYSWWNITSLIMIGKLDWINKEKLIEYILECQDLEDGGIADRPGNVADVFHTFFGICGLSMLGYFDREKVNHPEYEKIRRVHPVYAIPVDIAEKLELTAEIIEPTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC16</accession>
    <name>A0A8K1CC16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC16"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31748" checksum="59B29969547E3538" modified="2022-08-03" version="1">MADHREEATLSHQEAGLVNVVNDKPEADYVGLTDGVSKKPRFAVSNPHLRECLAEFLGTFVMMVFGVGVNNQVTVSEQANGIYLSISMGWGIAVLLGIHASGGVSGAHLNPAVSTSFALFGKFPWRKVPGYIISQLLGSFVACCFVYILYYQRYDAMDPDRMTTQGTYATYPNADISIGVAFYTEVFATAMLIIGLFSIGDAQNQPAHPSAGPLHVMLLIWAIGMALGTNTGYALNPARDFPPRLFTAIAGWGSKVFTTRNYFWVPIVGPVVGGAIGGFVYKLFIENHHPKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC23</accession>
    <name>A0A8K1CC23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRUD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000316</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC23"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="424"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="747"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="685"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="817" mass="91346" checksum="CDCCC4816A627E17" modified="2022-08-03" version="1">MDTRRAPGHRAPHGNKRFHRHGHGGGGGRHGNGGGAHPSAARGSFWFKGEGYNDYEAVSIDEDVVGIHGFLNGDAQGFPGLVKQRYADFIVHEITANGQQAALTTLIKRKRGVQNQFIELVTAYAFEATSTESTTETEEPSDATRQVHKFIRDVAQRLGRQASANGKHAQEVMEQRNHGKLVAHITSELGEKMGGEFAEFLQKVKARKLQDADAKANGTATAEGEHDENDLVFYVGGLNEKHERVFLHETMRRYGQGLITADTITAADNRQVIRVRRTTSGPVRKGERDPRREWPVDRPDYLQFVIYKRNKDLVAIVNQIASVLKTNPSFFTYADAKEKRGITSQLCTVYRVSKERFQNFSRHMERNLDDQHYLVGNLKYVSKKLSSSDCLGNHFSIALRAIPDETQLPTAKLVDLVRQWETRGFINFFGIHRFGNSSTPSHLIGRAVLRKDFKLAVLLLLRPQDGEASKIREAREHFRQHKDVAAALRMFPPFLIPERAVLEGLLQHGMEANEIAFRNIAAHLRTAYVESYQHYVWNQMASLRIRDHSTTQPIVGDLVYEVEVSKNEANQPKRRVIALTTENMDKYTIDDVLLPIPGYDVQYPENAIGEAYRKMLSMDGVDFASWRTMTMSANHNPFQLQGSYRHVVKHAQHVTHEIKTYTDSTQALILNDVDRLLGRTAPICEGRRGQPKDSEANAATEAVKEPAKPERALVLHFRLDHGSDGTIAVRELLKQSSSIHVQWQLRDQKDGTSVGNTASSAVVPDRTRPAGKTGGEASKKRASTTALAGNRTKDAKVAAPKKSQVAIGRPGFSLGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC75</accession>
    <name>A0A8K1CC75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000391</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC75"/>
    <dbReference type="OrthoDB" id="78227at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36688" checksum="83DC6EAFEE48BFB9" modified="2022-08-03" version="1">MGIFAKESLVQFMAGAGCFSVVRVALHVQLTIVKTHNCLVQIQMLVLVILGAHLVANQHYHQLLSNSVKHAGGGLIFTGILYILSALLGFYSARSQNKFLLLMNFLLLSILVFLQVMFGGIAVGETTPYYSFAFQEACLTVSGYEQMSFPDQELCEKFFQHDNFAGMSLVWQSYYTKSVSDGSYRAMVLNFQKEHFCCGNGLPMHCVNDSRPFPSTYPDPVVWKQRRICDSKVASSYPATKECRVNGRCEYELPNGLCGANPVTSTSRGCGAYVFQKLSNEVAAIGAVALALVMFPIIFIIGTVCLCFKRRDEDVMPSIDFVSKVKIYIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCJ3</accession>
    <name>A0A8K1CCJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphodiesterase</fullName>
            <ecNumber evidence="4">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCJ3"/>
    <dbReference type="OrthoDB" id="68317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0140">cGMP</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="875"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="852"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="860"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1251" mass="138964" checksum="449FDF513953C783" modified="2022-08-03" version="1">MPTAMLNARIRHVPMATESPRDDDGSVRKRRRMTIIDGDQLLAMQAELATAAANASTQNASAPRVPDGRRLSFHDTARDIARRRWRLLQKHVCITQWLSKDLMRRQVKRFALAQESLVDALMTSNDDFMEVFVKIREQFLSLLDAENCFLSFEANRSILEFDGRSIYPSTRAKRGLLRQALQNGQPVHLFHPSTASDEPYMVDGVPQTIDVRSYICLPLVDSDGKVQAVAEIFNSRQDVTTVSTWLRPGCSNGSLHVLRNFVGNLIKAFAKRANISDLVSSRVMAPSASTSANASLPLRVSHGAPETEMNGYPIESLVRFLRHSVSVEHCSVFAYDKDADLLWVRLSDDSWSPPTVKCGDSIIGRAAMTGEPIQYSLPHPNSGDEEEQRAFNEHFGSLSLPMDSVRDVLCIPTVTTATQKLNGVVFLLNKTDKTPFNEAEIAMSINLCRHIGHALHSSELHEAILKAQGKAQTLLDLSSVLFRELETNALLVAIMDAIKKPMNASKCCMFIMDDEKHELVAPVGSDIANDTDQEIFRIPANEGIVGAAAQSAEIINVRDAYRDSRFNPMVDRQTGFVTRSILAVPIKDTNGAVLGVLEMVNKLSKQYFDKDDEELARGIAYYLAIALKNAKLFEAARSAMRRSDALLAMMQVISSSNENVADVFKALVDTACQILNVEHGALFFVDALSKTLFCRVGSNWKGYTIPMGKFIPGIVAESGDGVTLAHARSHPDFDLAYDDLVGLETSSLLCVPVKSSSSSTASHVIAVFYAANKLTGDGSSRASIRRAVFCEEDIKIMNAICNEMSSVIERRAWELVFLVESSNESSSDMMTEVTSSFLSQYTTTPSLPRRRSSFFRQRAPTPTSAAPSDEIAQQSTGLSGGLLSKVFASSKPTSSDSMARIRDWELIPWEYSAPQLVDLVLDMFEYFDLLQRYQVPRATMRRFVVSVKGQYQDIPYHNVYHAFTTLHVSFLIVSSQSSVGSGTLSSSSETIAQRIHSNSVSGDEPPRVIHLLELRDILSVFIAAFCHDMNHNGRTNDFHIRYRTSLAMLYNDQSVLENMHAAACFETMRRPGHDILAQVSVSEYRQMRKSIIRAILATDMHNHAGIVTQLHEKLKVDVFNPEDETHKELLMNAIVHSADISGPALIEKIHVKWSLQLLEEFNMQYEEEVALGMTPTPYMNAKPGSPELGKLNLAFIDSCVFPLWSIMHTFLDGLDKCLENIQSNRTVWIDMINNPSLSTVTVASEESAEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCP9</accession>
    <name>A0A8K1CCP9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCP9"/>
    <dbReference type="OrthoDB" id="118693at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="48113" checksum="BFA80B7E7A0F84B3" modified="2022-08-03" version="1">MIDVDEWAGLFRTLVTLDADVHLRYRLVRAQCEELESIQRYMKQVRTARLQAQDAAQRRTEEAKEEAGIMQASLEEAIQRARRIRQEIAEKPTVKGKKNGKETDESDDLSTPRGLQDILAKARSIRAAEANNSATKASSEAVVVVTPIRLEYPRRMKTLMEKLEDLEAAEREQSFRFVFCKRLNAHLAMRQRPSNSETVSFSQSELAAVQVSFPKQVQRLTKAYNRLRGFLIERVNAEVVENAFRTQSLTALFPLYCRIKQAKKMLKTLNEEANALARRIPPRPRLSEAAIAHREKMLRRLRKKEPTSSDNPRAQRTDMYLLKSRIGRDLEAHSETLAKLNQAWESQQGSASEPTAHYSNAVQHTILVQSSNILLQTFQRAFSGSPPDPSSPEFCEIMMLLRFVDSVVLHRGQKQRSVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDI9</accession>
    <name>A0A8K1CDI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDI9"/>
    <dbReference type="OrthoDB" id="6022711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="143"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="274"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="634"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="746"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="943"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="480"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="858"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="943"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="955"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="984" mass="107816" checksum="302B253B8995C2FE" modified="2022-08-03" version="1">MEYEVLWGDGPLGLTLRPDLGEDMPPVVGRITRLDSAAALAKVAVGDMLVSINGMDTARQGYDHVVDLLQKIPRPATLRFRVPRQQSLGSVGMSTPKLSSSSLLRDRSMKAPSRSSATSVSSVSSSSSSSSRIKHEQYTVVWTEGPLGMILRPDDDDVHVPCIRKITGKGAGTGMERAAVGDVLVAVNGQETKSLGFRSTISLLKTIRKPAVLKFKRMHRRISRRRSSRDELGNGSPSAAMPSMSVKLSSPMTSSPSPPAMAKEYGAYDIVWREGDLGLKLKPGHRDIPILSKLTGKGTASGLQNAAVGDELVSVNGVLVEGQAYHDTLRMLKHSQKPAVLRFRPNADRRVSTMSTKSTRSNPSTMREVAHVRSKHVPIYDSGRPTPPTSSSSSSSRHARDPSSERSRTRTKKRIPLNVAMELVAASLGMDLDTATFAGLPITEIREGTEEAHLLRVEAKMCIQAKAEHKRNGLPAKEAFMRAQQEARVLQEALQKVKDQARQYEKFLEQQKKETVLASAIRNKPEEVVGRHNNLIAELTGAIAPLYRESYSEDDVIPMKLEEQEKLMDDLHTVMNIPVVVPKTKYCAECGATEKESKLDLDDDGQYYCKDCWDNFLNGGAPSAAATPDVIPEEEVPAPEAPPSPVPAPKVPSPPPSPPVPQSPPAPAVVRGESIARLAVADREEEERTARLEAEKKLMELQELTRGGSTLSIGRQANVTPVDRTRRERRGLEELAQALLEEEERARAEGNLTLAKKLSAQRARTMAESKAEQNGQSPYPSLRDVFDSSDSGFYRNGKSGSTNALHVPETDSGTLKRAATMDYKPKPVEPTPVPVPVVVPVVSPPSPPPAPEPTPANDYDDVDEDEEADDQVDMSDGEDDVLREVEEKNFALAKQLDEAHSVIERARQSIMLGDDEDDIMGDLGLSDEQINLFKKLTSQADERMSMVDRMHPQDESDSDSDESVFEENDGEEDEEEEEDDGVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDN3</accession>
    <name>A0A8K1CDN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000725</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDN3"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000009">
        <property type="entry name" value="Probable E3 ubiquitin-protein ligase HECTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="12">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="13">
        <location>
            <begin position="158"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="54869" checksum="60305FCF9E15FBF4" modified="2022-08-03" version="1">MAKAACEARCAALFRLCATQASDSGCGACIVEYAGASSGKTACVREEASGSSKSSGGGAGTSSSIAVEVTLGLGCGVLFFFLVVSMARRGWFTWCTRLRRTQQYRGYFQSTSPRWQCSVCLHDNSAVHKQCVLCASDSPGVHREHMLKQSMQLFLTAPSTTLRRHLRVDFMEEPGVDGGGILREWLHLVCSSLFSDALGVFEPANSSIHQGYWINRNAALRCRSHLQVLSFAGKLLGKALLEGMIINVQLSIPLLKHLLGVPFSLTDLRNVDEQIYSSLVYLLKNDEVEQLGLTFAVAGHELIPDGANVAVTDVNKQRYVDRLVKYYLFDSVERELKCFTEGVRSVIPGNILHVFDYRELDLLISGLAEIDVVDWKEHTDVRLLDQDLGRELQIIEWFWDIIGAMSQIERSRLLQYVTGCGGLPVEGFAGLTGLDGLLQPFTIQLTDTASNSYTMLPYASTCVNRLDIPMYSSRDEMEEMLHMVIQMDVTGFNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE74</accession>
    <name>A0A8K1CE74_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE74"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="201" mass="22356" checksum="E74D3B138A91B2A5" modified="2022-08-03" version="1">MWTKCGRVWTHVNRNERNKVGEGAAPTPAPAQPEAPKPAAAAPAAAAPALNNSEHVFASPLAKKVCNYRIVRLYQTALVCRCRKGDLAPVKLLLGNGTRDNLAHITEHCIKLHPMDTWTWLRSYWNKKRICADGFDFGRTAPHKADREGDCRRDKNGLTQLHVAASRVSFKMTSFLLEHGADMDASDEGDVRRTISRSNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEH5</accession>
    <name>A0A8K1CEH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEH5"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="35"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="36860" checksum="A61EA4C78940B7AA" modified="2022-08-03" version="1">MAKGLVTNEPTASGEESVLWQDEDLSRHRLDASMVQVERLLGTGMYGEVFLATYQQQRVVVKRLKDRNSSRQQIQQFVNEIKMMANFRFPKIVRFIGVVWTKESDVAVVTEYMAGGDLRAYLDSTKRRARDGWTMEKYRIALDIAEALVYLHSLDPPMIHRDLKSCNVLLDGEMNAVLSDFGTTREVDDSSTMTAEVGTALWMAPEFFGGRRYDQSADIYSLGVILSELDTHERPFRTDDLESLDPVHVIGSVISGSVQLCFLPSCPENIRALSIRCTALDPADRPTTLEIAYEQRRLLRVEVQISRSLSRLSQGSSGPRGSVYLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF86</accession>
    <name>A0A8K1CF86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cwf19-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF86"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF4">
        <property type="entry name" value="CWF19-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="3">
        <location>
            <begin position="352"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="2">
        <location>
            <begin position="486"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="63590" checksum="7193EFD2BADC43BD" modified="2022-08-03" version="1">MTKVLLCGQVDGHWSLVWERVRKLNAAAKGAPFEALVCVGRVFPFPVEYVQEAAQVPVPTYFIPAFEDASQWENDAAQRAIYDKMQVADVGAPVEVFKNCFYLGNQGVSKIAGLSVAFIAGADSNDPFGFSTKEVRALEETIKAQSDDVDFFFSAQYASHFDNLLADQQVPGELKTIQTATALDELLVTFAPRYHITSSSREADKGVFYQRLPYVTEHERSGRKQITRLIGLCGVSSSKDKTKKYLHALQVTPSASQIDAEKQQSDIPPGTTQNPYKQHAVQLAEPALKRQRVSGPPPPPPRSGLSAEQVAQLTAQSGQGAQFFYDQQIAARGQRPDALRHPQRNRPPVPERTECWFCLATPSVERHLIVSIGQEAYLAMPKGAINEDHVLIVPIAHEASTSKLSDGCMKEIARFKEGLRKYFDSQDKDMVLFDRNILTVGATHCHLQVVGIPRTHAASAHQVFLDEGEKYNVKFQELKADDDLYALTEGKPYFYVEIPDGQGKTVRLLNFVEAKQYMQFGRHAAACVLGVPRRANWKYCVVPKHEEEAMTKAFKSKWQPFDFTLEYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFI9</accession>
    <name>A0A8K1CFI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ALA-interacting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFI9"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="44980" checksum="9382DA5E87614C9D" modified="2022-08-03" version="1">MEEKSRKPEDTPFKQQKLKAWQPILTPNWVIGTFAVVGLIFIPIGIILHTESENVVEYSIQYDGKDTNTDSSNVVQLGKGCYLKSDSDRDTFDVDERGCLITFTIDKEMKAPIFLYYQLDNFYQNHRRYVQSRSDAQLRGDASASTSDCSPLQDSTKVVKYNSTNSKPIDSTEKVYQLNPCGLIANSLFNDIFWVNSIQVDGKKYYQDDKYNDKKVVNLLDQSGIAWKSDIDTKFKNIAADQRKDTDLYLWQNEKYRYVIPMYEGQEPVANKTSWTTPATSYGVQDEHFIVWMRTAGLPSFRKLYGRIDTDLAEGTKLEFLVSSNFLVTTFDGKKSLVISTTSWFGGRNPFLGLAYIVVGALCMLLAILFFAKHKLSPRKLGDTRYLVWKNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGS3</accession>
    <name>A0A8K1CGS3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005134</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGS3"/>
    <dbReference type="OrthoDB" id="494993at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="654"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="699"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="840"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="860"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="882" mass="98831" checksum="3682FE3911C409BA" modified="2022-08-03" version="1">MKKPAVAADAKKAEEPKKKDEAEDDPEDDGDDGGEEDDDESEDDDDIEEDTGLTESQNRLLYLISLYSKPAVRAADKEEWIRKPALLVLLYEAIVSKALDYDYAPSSELVENKRKYFNISQEGKSDIDFLREEDLLNGLKLSSKSYQPVTCYQISEKGLEIVSKIAKADKLAVNDMAYAPGTLHLLRVEWDGEEYWLVDDESGYRRLSSVTETEDVSYVSSAYIPQCLRFGGRPTLSNAHRAHECGVSDSSIRDQLDEIITLNSVSLIVSEYIPFGSNQVVQLNCNLGSTERVQGGFFTAIVDDDSAGTKISVDPGLTSINILDYTMTNHVNFEADIHFPEAPGVVQVETFGCSLTAAGSCFYGMQVEAIMDRIKDNISLDHLSRLLVDVHMDSSKIVDSVLSAYQRSLLNLIFSGQAASRNKINLIIANEITPHLTAEEYMDKGEYENELKQVIGDTRAAFDISEHDTLIFGAYGLLIAGPNSRHHEPLLCSFLQYESMNLFTQNFFARMFIIVDEMAQVRELIDTATKDPNRLRQIRDRLAVLSKEVIILEETLGYLKESLDEAIVPPEPPEQAGRALYERLQLGLLANQLKRRVKDLHKNMAGARHELEVLNEMATIVSNDRDFQQNEAIRMQTRALCELQEVNERTAATLLLIQVMLAGLLAFSLLDRVTGYWTLTETDWMKSFLEVMMYANPGLWFFFSLLIWGIVGAAIVVLLRYLGFKSRGIVSIKLERKVPIYLKNLSAFLRTKLLEDETHHFEGGIKVAKVIWTEKDKKEWGGSAPTIELEYDEENGFMLRIGISYMKRKAAKALAFNSNELYTRLMQELDKAKIFVNPESAAATSSSKSAGTALPPSASGDEKNKEEKTSPPSSTSDKKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHN0</accession>
    <name>A0A8K1CHN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHN0"/>
    <dbReference type="OrthoDB" id="271164at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="35005" checksum="3399E6C9992784CF" modified="2022-08-03" version="1">MDESFFNVRGPWRGLRIEQYARAQSGIWYYQVDIELRFPRLRALWEDEEDCDDDSDVQYYSVRRRYSEFLQLYEKIKEEIVSVAMERSDFDLKYWVLPPFPQKEYISSAVLGLLWRTTTSLQVLEERRRMFEKLLHWIEQHSILRESPAYIEFLGAPPQLSDGYVSLKEYTSQNWLSSLEQLREKRRRRSCSECSSCSLPQDEKVTSFIDVRRQYVHDSTYTVTQYMETRRKRYRRDDGPGKWKHMEELDESVELVVECRRGVKRLAAPMEDSHYNPKKKRECEPPSTTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHR0</accession>
    <name>A0A8K1CHR0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHR0"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000608">
        <property type="entry name" value="Glutathione S-Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22447" checksum="7E302697A285D0ED" modified="2022-08-03" version="1">MSSQIKLTYFDSPGRAELTRLAFVMAGIAFEDERVKHEDFAPVKPTLPLGQVPVLTVDGVVYPQSMAMARYVGRLGGLYPTDPMEALKVDVVLETLLEAVTAYAEIHFRTTDEEIKKEKTEHAFEFVFPKIFRLVESSVHGDFVLGTMASLADLYIFVMVKKIMEVRFPEFDMSPYPKMKAIAEAIKTTPRIATYLASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI94</accession>
    <name>A0A8K1CI94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI94"/>
    <dbReference type="OrthoDB" id="63702at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="44815" checksum="013F0FC85BFBB49D" modified="2022-08-03" version="1">MVDALPIPLLEMDDQLIEESEQLLQDIESSRLSEDERSKRSRSERQSRQRRQANLERMREQVKTLQWIVKHADEVQEAETTQSATQLVDPDTARVQSFLQRSLVLTRKARKLKHEESQMRRLMREHELAQKLLRSWVEPPKKSPWELDIDVWNGLSAVHFKPWTMDDCVEVMKASLEMIHDLSQNKEFVSSGCEFMGWTDRRRVDIETSTLHFSFSKSFANCDTQSVFENYWDMHYTAEKLCQHMLGWSNKLHVELLQKVSDDICIFRRDVQYPGIDTRFHTVYIMFRLRSPKGFIHCIRTIPTSLTRETLDPEGGWMNNFHWTMMDYLPDPVTGDLTGSRVTFSGLISSPSIVFVNRWMMELAVTVIRAESSFVSPMFLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIL8</accession>
    <name>A0A8K1CIL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein odr-4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012876</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ODR-4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIL8"/>
    <dbReference type="OrthoDB" id="21458at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029454">
        <property type="entry name" value="ODR-4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33966">
        <property type="entry name" value="PROTEIN ODR-4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33966:SF1">
        <property type="entry name" value="PROTEIN ODR-4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14778">
        <property type="entry name" value="ODR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="49372" checksum="EEA53D450057B950" modified="2022-08-03" version="1">MTMSRSRQVHVASSVDAYWSHAIQQRRRFEMGLLVGQSGVLSACDTVLAATQVPAECEDEAVASFEDVSSDWVCDVAKQVDRMLPGGIKILGLYVISASDPRSVMDQASCYLRAIAEAVAIPTEFQSGLETDDVQCIVHISPSNSKRVAKSFWNLLDAAKTAANPAELKSPSTASCLETTQYTATIAIDQLLSFAHLKVATEQPVDPTVVIEKRVDEARQQLLPFVQRIWHARGIKSRQTESSSQRIDFLASFGATSSSAASKEPVNSTGRCQGVIECTAFVPADETSRPVDLAVLYLKQDFVKSLLVRIELLLERWTDDSIVGSATQSRTFLKGSRVVLPKRALLPWHSGVTTFSEALRLSLHIFPDDHAIDAAQNALEILGATQESEVDEAQLEWLEDDSKPHAHSTQSFTATSATQAAGLVATASPSSSNTLFVLLPVALLLLALIMQFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIN5</accession>
    <name>A0A8K1CIN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIN5"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713:SF1">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="202"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55765" checksum="204957E8FCF7B9DB" modified="2022-08-03" version="1">MGVTEIHGEADWNTAMRNAGGKLVVVDFSATWCGPCQFIKPTYEQYSRQYHDVVFLGVDEAQNRSLIGALGVRGFPTFHFYVSQQKVDELVGADPNSLRQKIEQWRQSAFNPFASAGVTLGGSAPASAEDAREARLRRFNNLNLVPTTTPAPPAAPAAPAAPAPAEKDLSKMVCDPVTGQCSIPSEEEGKTDEMEGQEGIPPVNENFLSQMTDMGFSELRSRKALLATDSASLEVAINWLDEHQDDEDIDEPIKFVDLSKHAKKPLTEEEKAAKVAELQAKIEVRRKEREEREKQEAKEKELARRTTGQSMQEAREEYEALQRKLAADKLKKEREDFKRERERLKKQLEMDKAARRAHGGKLVGPPVDITVETSGEAQTEVKKTSPVSTLSPEEQVVFNIEKLKKYRVGGDGLTALKTLNVYVKNLIEKPDEEKFRTINLENPAFRKRVASLVGGVALLKALGYEKDEADGLLKLAVENRKDDLLQYTRTSLERAITELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ05</accession>
    <name>A0A8K1CJ05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ05"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="550" mass="62116" checksum="591B81E9CF9C0822" modified="2022-08-03" version="1">MAKMEHVYMFVGTFTAPNGTTWKFPDDLCLNQWSATEVVPRKEADRLSKHMLDSEWFPCYVEVRYDGTFVPIQQNVAGDYLCREMAAWTLHDYGRTWAEVFIPNPDNKYEVLSLVMPPDQEKIGYQRRFPLSVFRIAGGGAMINTKIFMNQKFLVFEQEAGVRCLKPEIWKDGRLLQYGLARANLSLISDGYFELTIRGMIYIYIVLMRIKCVYLPIFRYSRVHGFPVNGSFETIHAGLRYGTEVFLLAFEALVSLDETIGTFLMLHEARTASTTEYAWLCTQASKILWIPVAIVTAVSLTARALSGGRLRLRVSPDAYPMLVPYLVFYAGPKIVETTPNLFQHYHTTTAGFGHVANSAKASTGGVRTILSLMHIVAPVVWPCTWILLAASILQQLTSVYFLGSGHRGNNHNLRHITTFQPISHDLMLHEHGVAANKFTQSLGLVIYGYERALVADFDLPILVRYGRPVLLIDPAAALKSMREGKATTLFVIVADQDKMYAHPLHLQSTALQIRTILPLHWQYTSIPARDAKFESTTAVDSVMTKKPSWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA0</accession>
    <name>A0A8K1CJA0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TFIIE beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJA0"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="7">
        <location>
            <begin position="31"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="44185" checksum="44549D1769AB8E7D" modified="2022-08-03" version="1">MSWRNLAYGSQAAAEAAPTVAPAKLAPVKEVVPQVDASSVPKNDGAKVYKILEYLRKIPMHQPVSVKDVFQHTGIDLTMDEQVDQRLKNNPKVRVDGEMYAYQAKYDIKNRMQLLKILERMPEGMPIEDFIDCYVGVENDLNELSRTGEIICLKNAENGAEVFYPRGMQFLVDVSGVATVEPGCYYAHSTVDISGEVRRGDAIRVGDQWFRASAAVKTNSSARPAAFAGMASKSVASTRDPNVSKKIRYLLKFDKDHIPLDAPFPDAKRREIVTDRWDSLPQRGPKFQMIKHGCTNDIRQLWRDTLRHWPTDRAEFEKKLVQAGLTTQAKVDANRRQIKRRLKEDKRKPRMRKQREIKISNDHLIGTELGEILAKGGDDGFTLGAVKFEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM40</accession>
    <name>A0A8K1CM40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM40"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04818">
        <property type="entry name" value="PA_subtilisin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF411">
        <property type="entry name" value="OS02G0248440 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="291"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="394" mass="44268" checksum="6CEEF4673352E0CD" modified="2022-08-03" version="1">MRRDVVYARVGGVSTRLLLLSMTLMVWTTHVTALIIERPFYSVMTHVSGEFTDADTLHDAALTSKEVIPVTPFHACEPISTDLSGRIALVQRGDCNFVKKVYNAQRAGAIGVVVMDNAARDEAPHHIIMQKDENATQLTIPGVFVAYRDGERLLHFIRKAAPWTPALVTINEVGEMPQDRTKYRFWKRAVAYIFLVSVVCALSSGLSIISSFLFGFVGTLWRSRVTRKLPVIHYVPHLQAELLERALRDAHILDRIVLDDDDGSTPETEGNTDNMSAAVDENEENTSGESCSICLDDFVVHDRVKVLPCQHFFHVDCIDPWLEFRSGRCPLCKQDAISALDEPPKSFFGFTLPRLEQVLRQEHWFHTFFLMLPASLVSCLIVNAAASVIRGMWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMI1</accession>
    <name>A0A8K1CMI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ANK_REP_REGION domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMI1"/>
    <dbReference type="OrthoDB" id="10254927at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="272"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36845" checksum="F971DEF24B1DA947" modified="2022-08-03" version="1">MNKSAATNAPKLTLVDVAKEQSNKVDSTATKSDMTDSEQPKKLTLMDVAKENDGPKTTATVSLASIAQEINVDERQSMDAAITKAATKVKQEQHQQRADALKETVAQIKMEDARAAEVLQVKVEKGSLAEDTTPPKEVKTNASRLVASTKEAEDDGGYSSFEDEEDSKSIKKKPKSTGKRSKEADNQSEEASAPPPRTTASDTPESKEYMRAVYRGDIRRVADLLDDGELDINTADQHGWSGLHWAASQGHSKLLMVLIKRNAEVNAVEHINGWSPLQVAVIRQQVACVKALLWSGADTKPRDVYGDSLSDCIRAFKNRKTRERMLQLLEESRAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNB9</accession>
    <name>A0A8K1CNB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNB9"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF12">
        <property type="entry name" value="ENOYL-COA ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29568" checksum="2E88F31588AAAEED" modified="2022-08-03" version="1">MTTDVVVRRYVHAKHIYVAELHRPRRMNAVSQLVYQQLIQAIEEYEANDELHALVITGHGKYFTSGADLSEGMSMDEKGNQILPSKNWACKFMDAMVKCPKVLVAAVNGPAIGIGTTLLLHCDFVYAVETAFFWTPFMRIGIVPEFAASYTFPRVLGRQLANEMLMMSRRVDTKRALAHGLVTQVYPVDGFLTKVFEDLAPMVNTPLTAQSLPLYKSMLRREDEARVREAIYHEFVELDRLFLSGAPLKAINAFLSAQKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNN5</accession>
    <name>A0A8K1CNN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ERV/ALR sulfhydryl oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1562405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="2">
        <location>
            <begin position="789"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2338"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2475"/>
            <end position="2629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2475"/>
            <end position="2495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2587"/>
            <end position="2629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2629" mass="292447" checksum="854831273668D7F4" modified="2022-08-03" version="1">MWTTLALLALLVAFGAKLLAGLLGVVLTAVQRGGLLSNIVVDDETKLSVVVGTIQISVWRCVWSFFRAPSREKLCLIEVRSVQLLISIQHKPSGDQRPKVSAKTMGSVDLSASFKSLKHPMWATPCEWIRRLSFLCHFVHLIGVAVSEIGVDVIFDVGKVQQTVASIQHASIALQANYNQSSSEVSLALDISRELSTFIRIPAVEGSVILGAIELRARFPVSRGVGDTRAPLPSLISVNLSSVSADVDFQCLLRVITSSPGSKTSGFSSCEPSCVEVGEVNHSSTLLPIRIMEAIPDEIELHLSQIDIAIKHPKSYDTFIVSLTKLGSRLVQDRLHWKPSGSDEVVERKATLDIDQISLGADTDAAQTSASRAQLDNIRVEVDAKIASTALDPDEAEVDTSSCELAVSCESRVAIEGKKLFVQLADDLHPWTLLLWEILRETSSGFSGEEEALLPPHGSTSGNMAMEMAVQAKLHRSEVLVISREEKCSVLPKGVPSFGLSTDEITVLAHPFVSDEPLGIRSKANIQCSQLKVIQFPKDRLLKTPFLTLDFVRVFIDPVSPMTLNQIPADVEMEAEWLEVRWSPEALHAIGGLLELGIHVMSPFIQEAPDWESDLKWNPRVRQSIPNMKTIGDVTEDVIAESESIKFRCKVKRTLAMFSHSDGSVDYITVGFVQMSVEEKTGRFRISILETNVSHTESFGNVRSPRKGGRSLGSQQHPVRSSTNLSGRKALERLSSNSNRLGTNPDSDHYLYVKNFSLEETRVPMCPKTVVDMFADEVRVEWSVSMQVRIMELIRRITFSTWEMLYRIRAAYAKDCTPSSSRYNRYGGVNVDMSDLSECERCELVFRKIISASGDTLHRMRASNIEVQAKLHDDFALQLYVSLFGGDDLPELWTFRGIRLLCNATELLQVNEVRVRHTVDKRRDYTFGEFEELLRIRQVACRRLEQTARRDGVIIDADNVRVNVPTPFDWAKLAQAIENEIVPDMGKLALILASEWRPQQAIFYQFFLRAPQTPGQMRVWLEISNFAAECSDHPMETWLERLYPLWVEELEERDLRTHVLEEQLATLKLTNAEMLQVDAAEEMKELLDEKNAKIYAQKVKKLQAKLLHAGSDLKRGSFLSVSVGWISTDISFGSNEMEIVDRIRHLDQATGALDSAITSMEMPSKDWIPTFSLLVHQNIAVSVQDMSLRMRSFPTPVLLCDNIMCTGDVIISAPSCGDISKFKLTACLRCFMDVEVIVIRPIAFFGPGYVYTMQELASLALQVLPSLVLDVDKANGTAVWDILRRVFHGRARIIARDATLRLLASPTSFDLADFLEVALQSVAIEYSGGSTDVHIDRLTAKIEPEAVVNVAEFSSIYLHTRLEWSATGDSRLHYVYPVEFRQIDNLKSERVLVDLHRRRAILTTDTCCTERYFQPFAATGVSVFVNGRIAPRVVAGENGSTMTKRDIAARTAVVLYTKHVEWLIRFARLYQEIPKRRLPRQRLADSQAVVAPTLSPSASPMLQFLTVFKGLVVSEFDIVGLDVALYHSEKSPVGIRACINDKIGFSGSLLDEGHQIIRDSRDDKTASQRQIPIHWDGYKWLVHDVTLIVHDIQVRICTPRTGSRGESLLSVRGMCLNVGGNSHRIRAQFAPTAEPTVREAGDIPLAGGSDARPKKKNILEHFAIPQHNPYCFRDSDRDENSVNYLHTENADATSNSLQLAFFEECRELGFVLGLAATEAKVLVTLDAIETLVDIIENWIHVIRSCLPEIMSVSEDSITQLSVPPAEQLPAEMESPKKVKSLADDPRFGAIFRESILPEHRTRSFNASATAHVGQEAEDSNESVQAPSSVVSPFIMVRFMDCQVNFQDSQNKGSILLVLNSGTLRDSISADSRHEFIDLKVEGVQLFTAPLDVDVKSRVIWLRTLADGSYCYSSYGLLKQVIAPIPTHVSIWVDRDVAVTNKVDLQIPSVQVHVHRDSKDILENLITSVTAIVTTKIAQYQSPDYVKMLQGYRSLSEPNLRSIQQLLNLKKQIKWKIAELQWNHTCRLNNYSSERANVALHAAENGRHVAFEVETSPLFRRRRVSSTSASSITTGISFTGSTATQMETTEDIQRFYQQLESITEVLRSLIAAEQKKRQPNPNVQLEFALRDASLTLSAANSDIVRAVMGDLRFKMKMFEDQSGSFTLTIQNVTCDNVCPGAPFPELLIPAMNSKSWSGDNTFLRMDADVAPPVGGITIVKHFEVNVHPMQVCVTQDLILQLVAFFAPVASSGRQEEKKAEIRSQFLSVPQSGGSSGERLFKKAAKVAGKAAHPLSLGWGRHRERSEENAINAGRLKSLQVLHDEAATWVARIAKSESDSQLERSADSRSSSEASEDKDIAEMQDRAKNNILFKHIRIGTLDVVVTYKNKKLNHQSHQTLEDMRGFEVKIHSLVYCDKTCSMMDLLLRMRRDIIVDVLSQVGRNFANIANFLRDQFDITRWGTFDALAPLKNLSQSLGGVSPSAQPSRTASNNTSVPFNGLSVSHEGAQRSPRESQVSSPSDATKVFQLQLPENHPSLRKKTATHNPVPRPADIKTNVGMDSDSKEDGEEATAVVSPLHAQNSKRLRKMLSSLFSKSKKSNPSSPSAAATASVSADYDQARAPSAPATPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPH9</accession>
    <name>A0A8K1CPH9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPH9"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="55504" checksum="B45D84AC3CAB1846" modified="2022-08-03" version="1">MYLMGAVSQREMEKIEQECIGMDSFKYAWLFDKRRDARKRGITIEVLIASQTLSTSRCAFAVVDTPGHLDYYKNTISGIALGDCGLLVVPAVWVSQSDEMAVVRDQLVTAFTFGIRQVIVAVNKMDTVEYAQESFDQVKTEVAAIMKSTGFVPEKVYLIPVSGWAGDNLIQKSTRMTWFDGPTLIDALDHVVSPRRAAEKPLRVSLLEAYKISGVGTVAVGRVETGTMKPGTTIAFSPTGSISAVQSIEMSHQAVTEARPGDNIGFSLAGISAKELKRGYIASEDLRDPARQAIEFTAQVVFAHLDGLLSVGSTIVVHCHTTRVTCRVKSIFAKLDRQTGTVVDGNPKHIENGDSCIVVLVPTEPMTVEAFREYPSLGRILLREENCVTGFGIVKSVKKARKATEFTSLLAFSRLSAPLTVGSDINVRCRSVQAVCQVKSIVAKVDGPTETVADAQPEFIDTTASFIVVLEPKQPIFLETYQEHHLFGTIFVGGSTDVNSGFGCVKSVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPP1</accession>
    <name>A0A8K1CPP1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPP1"/>
    <dbReference type="OrthoDB" id="167011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438617" evidence="2">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29010" checksum="756A1B77883CF5C6" modified="2022-08-03" version="1">MKTCVFLAIAATLAVAVSAANVNIRGAQRDEAPASTDIRIRTTDVLNRSTGLLNKNRVAMDNNVNIARSNVLFSQNDRLAMAKQVEQALNAEEQAGTAVTLTRSVMRSVSAPDTDSSLMTKASAVVAAKGGDASTLSQRIADFVNAVADKKEQSIQSETPRGMQLSVGTKDILRQPTAVINKNVGMSDNQITMSRTTFAPLRNDRVTMSNNAKVANAVAPGSAIRVDQITAREGQDQDDASSEEMRVPDDKKEQFGWGWGFPGYGWGGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPX9</accession>
    <name>A0A8K1CPX9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPX9"/>
    <dbReference type="OrthoDB" id="100847at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="39725" checksum="2DBD737076FECAD3" modified="2022-08-03" version="1">MELFTASPRRLNESSPSESSNEDVPAQEPVRGLKVPTYYVRKNEITALQEEAAVLSKKKKRLMVEKGVDLVDIAPSLYENAVLRNTLQATSWAVGEAQSALSSHALNQVFNPLETYIHLAIDQDSRHHTLRSLRGEKLHKGLDFLANRTRFLDLRLSQDQTQSLTNPNGDIMSETLVVLPFPDHTDVKYVYESLLRVMSDLEFNLWERLGLVSVSDIEELPDGSASQSRYFTTLTPGVDFEKNTIKFKHFEDQPSVLSSPYGIIVEDFVDEDELYPYNPANRLRMDLTAATVVCLSDPTTVSVVRWYCGRFHRPQWHLPASVVDSLRSLMQRCGETSQRALREHLEASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQI2</accession>
    <name>A0A8K1CQI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQI2"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="5">
        <location>
            <begin position="293"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="555"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="464"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="594" mass="65056" checksum="5501AC43D8CE8FFF" modified="2022-08-03" version="1">MMGQPEPKSSAGTKATASTSEGSLHRTRPFPPRLERTRLNGQPPRVRKEPRARLDLCKQHVESSRATLACGLSWMRVKNLKNNRRSKTGEDDAGDGTEQSSTSPYKTPSPAASKGYLQANPALDIGADSPTDSSATLTVESVEVSELDLRHQATGHFDTHMGSMADATQQQTQVYASNGRADSWHDHVDRSVREAVHQRIVEYLKALKPNAPPKVLSKLPGLADRMEEALFKLASSEREYCDQTTLPQRLTLIQQANAKRLLQQQTPVLSPKEKDNGARVNGFPAPARKPLSEEQARVVFSCLQSWRQKLVNMYGAAPWEILPNQILAKVAVYIPATHQELVVCGVRDEQLQRFGNSLLQEIQKIVNALNTNVGASSQLQVNTALLPPRSGSPSTLKRSSPGSAKSSRKGDTTKRTPDNAANKKRKTTENSSPAVRVPVTSGGFLAQPPSFIVPAPVLIRPMDGTSTTPSASSLPALLPSGSLPPASSVSGKKSPFPSSGQQQAFFPRLPMPGAPSHEHDNRMHLLAQGAGQLSKQDFHQSPPHGTDQQLDAKTVELYEKELQTMRWLLQESQREKSQLENEVQCLRQQLQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQM8</accession>
    <name>A0A8K1CQM8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQM8"/>
    <dbReference type="OrthoDB" id="163200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="173" mass="19485" checksum="CFDC131080C8F454" modified="2022-08-03" version="1">MFGMSVFVPLAVLAYGSYQVFFPEVNLDVQTSPVLNVSAQIVKAAMMGALTFFVKQVRLFLGVALAGNLHLLFLVLRFELCSTWHLKYSKVLIYAVSSWSALCALLSTFLSEADRDSIPLYTMHAGWALQTLAYFYAVRRRHQQKKAQLKSGLFVTRHVQSRQQPAELVVAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQW6</accession>
    <name>A0A8K1CQW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_007853</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQW6"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="64"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW68181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="513" mass="55535" checksum="CF428C91F947EF0D" modified="2022-08-03" version="1">MSSLERKPTLPTLHPSVSITILDDETTPTTDAAYTQFLTPQATAVPVFHNGSKTLRVNNPVYTSAYLAMMQAILYGWSLSQLNYSKFNNKVDCDRRPIAPGTCLMFPGHTSTEWISVVNSWVVGGIIGGLLCGLFADRLGRKRTLMFNCAIIALGAIVQAASPTLLVFCIGRFITGIATGVATAICTTYVSEISPPHLRSVLGTIYVVAIGTGVFLVGLTPFFAATSSGWRYIAAFPIVIAIVFVLLAPKHLAESPSWLMARGRPDEAQDVLARLYGEENIDLALSWIKLPVVESQVEQQTYPPSEASAIRSLVSTQHRRKLILAVVLALAMQFSGINAVFFYSSTMFKEAGIQDGRIGSLIVNVFNLLPAIVAGQFVKRIGNRRGLILGPSGMLVSAIGLTIARVHHISALSIVFISTYVVSFTICLGALAFPVGASLFPQSLRATGTSIMMFINWCGALTIGVGYPFLSVSLDEYAFVPFIGTLTFFVIFFYVFLPDTTGKTPAEIQELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY3</accession>
    <name>A0A8K1CQY3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Formin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY3"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="38"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="8">
        <location>
            <begin position="551"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="487"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="961"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1088"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="240"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1088"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1216" mass="133555" checksum="5D6ABD99122963ED" modified="2022-08-03" version="1">MTDEARRSDAAMERPTFVRRGSFAGRDDGGGFARERDCGKCHKGFNLLRRRHHCRGCHVAVCKDCGRKAVRRGVNTKPQWYCHECIAGDDEIEVVGGGRATLHKRMSISSGAFGADPPSINTLASVAKFCIECGYELPNRVKFCIECGTAVKPTLPSPVPGQLERSGSEMNRASRSLSRGFPQAGNENLMMIDEQSDDPTDSVDGLEEELTVESDGRREESESSPQSEEDAAAVVHAESSKISEELLAQLQAENEKLRRKVERLRVKVVQSEQYREETVEQYKQALAVAEAQAQTAATAAPPASAPGALPIPATSAAAAPSASSGSGVTAKDHSDYAKFFKLLTMGLPAEQVKMKMQQAGVDPNVLDNPDAVVGGAAPAPVAGGAAAPPGGGILVKDDEKYAKFFKLTKMGMPAEQVKLKMSAEGLDPNLLDTPDAIMPGSGGAASAPSGGMTVKDDPAYEKFFKLAKMGMPAEQIKMKMSAAGLNPDYLDTPDAPSPNQKGGTGAGGMLAGLPPPAEAVKVDSSALQASLASKLQRGGSQKKPEEPALPKKDPVKPNVELRPFFWTRVPVNVVKSTIWMKLDDSHADFDPDEMEWMFRKNPVDASKKQDEAKKKEAAKDTAPPLVLLLDPKRQQNVSIAIARFRMSATEIKDAIYSLNNEVLTSEVLNVLISISPTSEEQDLLKNYDGDEKLLGNVEKFFLELLTIPRYTQRIKCIRYKFQFENRILETQAQLDTLQAATDQVTDSEKFRRVLEHILAIGNYLNGSTPRGGAYGFKLDTLTKLHALKSVDPRVTLMNFLLRQLEERAPEVIAFAGELPHITEAKRLSLDQLRADLSGYNSELAMLQGQVRAAKSDKIDEDKFYTEMAPFAKDAAEVLEELGRDYGTLESSYQELLTSFGEDPRKCGPMEFFAIVEEFVNEFKKAYRQNQTKEYQAIFEAAKQAREDALAAVEAEKAAQLAKEEEERAQREAEERAKRAAEEDARLMGGSEDSRALYMQIIATVTNWAQAHVEGDPSVVVDQFKAISRSFGIDEITADEFCTQVRQIFGSKVALKVIPNSAKLLSSPGKRKDLLIAFDRFSEQVKKAKEEKKKNGLERQKSKPRRSKVSVMQVPEIEPVVGEAAQQLHKSILESVQHAFGGDTKKMKVFTSNARKYGTEQISARDFYQYLTASFDMDFVGRLVPDLARLLQDAEKRHALIRALCESAAGWEKFSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY9</accession>
    <name>A0A8K1CQY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRO1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012484</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BROX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY9"/>
    <dbReference type="OrthoDB" id="104504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038898">
        <property type="entry name" value="BROX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23032">
        <property type="entry name" value="BRO1 DOMAIN-CONTAINING PROTEIN BROX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23032:SF13">
        <property type="entry name" value="BRO1 DOMAIN-CONTAINING PROTEIN BROX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="199"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="530"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="574" mass="62407" checksum="48F80CD69D5C7C51" modified="2022-08-03" version="1">MTTTRQNLPPCCHAVRIGKKDTPKVRFKSELTKFAVASGKDEVSRLAFALTEARSALQLDRSGYDASKTASRFNQVDDIQGYVSSVTSYLSLVKGFTVAPVELVSVAKPPVTEESLVSHLPAEGSATPAASLQEPLIGSTSTAVDTQSTRSKCLSFCNWKDVLTSSSIYTMNARIEYAQCLLASGLLMMEEASVKVDVMLAERVTEINENDLKIAYQLFLHAAGLFEACLTSINIPARAIGAEATDLSVEPTKKTEEATPVTTQVDESALAKWREEQRNTNSSSTTVPTSAPTADAAGTSAASSEDLSVLKRLPDLVNGRFPQLLAWISLAEAQELVVLRGMSREFVDYSLMAKLSMDLSMRYKECHAFTARQLPCATSSVAERIRLYCTFKDAYYAAVSCYFQGAACMEKGDAKHCAQAIADLKKASTLIQQATQRKAAYDAKLTSRDEKDRLFAIKTVYVRTEQIIQRDLHIMTQRNDSVYYERIPEPQHPCEPLGLVRVVALPAVGVHPIWYEKSVATCLHPSDPHSATNGGAHAANGTSATTRSPTTEAHGSVQESGPRRDSCCNGCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQZ6</accession>
    <name>A0A8K1CQZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQZ6"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050403">
        <property type="entry name" value="Myosin_RLC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23049">
        <property type="entry name" value="MYOSIN REGULATORY LIGHT CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="152" mass="17081" checksum="149831BE2B16DA68" modified="2022-08-03" version="1">MTQNLTTEELAEFREIFNLVDRDRGGSITKVELGELMDTLGIDTSPEEIDLMIHEIDQDSNGEIDFDEFVAVMSRKVNATYTSEQVKNAFKAFEGNSSAPGFIKADRLLVALTTYGADRISPEQAQELISQLEPDQQGNINYVEYVNMMMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQZ8</accession>
    <name>A0A8K1CQZ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orai family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQZ8"/>
    <dbReference type="OrthoDB" id="61124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.140">
        <property type="entry name" value="Calcium release-activated calcium channel protein Orai"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012446">
        <property type="entry name" value="CRAC_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038350">
        <property type="entry name" value="Orai_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501:SF7">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07856">
        <property type="entry name" value="Orai-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="28705" checksum="B03E03FF5D701596" modified="2022-08-03" version="1">MAAVGAVVDAVFGSYDLKIAKQWRDEDVQHREQEKQWREDAIMREIAWRNADLERERRVLKLENEKRIIDARHKQLSAISQLSALLAGFSMVSMVEINLPEDLNEVLMAFYGVVCCVVFIFMLLAMLTCTLLLLAVTRYVTHTLEGEVRDLTLIELDLVSPFYAWWLRKCESEWLLAYRFFRLGISVFLVEVALIGWVQFGHSLTTGIIMSTLCFTGIVYFQLRVASRWRYLVKFPDIVNPNMPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR02</accession>
    <name>A0A8K1CR02_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Poli38472_012193</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR02"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00587">
        <property type="entry name" value="GLYCOSYL_HYDROL_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="20" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035459273" description="glucan endo-1,3-beta-D-glucosidase" evidence="22">
        <location>
            <begin position="23"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="309"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="313"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU004336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="TMW67077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="519" mass="54982" checksum="42C9D0C59CFC9CD3" modified="2022-08-03" version="1">MVRVMPTALLASAAALATAVQALDFHCYGINYNIRNGPDWAPAETKCKKADLIQQELVKLKTVTDIIRLYSLTDCDQGNIVIPAAIKAGLKIELGLWVGPEQATFNAEKDAFQKVVANKDLVNNKNIVGVHVGSEAVYRGDVEPATAIKYLDEIRKISKAAGLDVPHTIADVGDMYLDYPELIEAVDYVSANMFPFWEKIDVEEAVDYFYTRIQDLETAAKAENKSVVIGETGWPSSGVNVNASDASPAAAALYFQDFYNMAHQHDFKYYYFAGFDEAWKGTDPENTVEAHFGIFDASGKLKTEFETLKLNDKTPAPSSKTPAPSSKAPGKDTPAPTSKTPGKNTPAPTKDGDASDDDDTPAPSSKTPGKMTPAPTTKTPGKATPAPTSGKGDDDDDNTPAPTTKKPGKATPAPTSGKGDDDDDNTPAPTTKKPGKATPAPTSGKGDDDDDNTPAPTTKTPGKVTPAPTVGKGGDDDDETPVQKPTPSPTKGTENPIATGMPTPAPTKKVKPGKDCKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR37</accession>
    <name>A0A8K1CR37_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR37"/>
    <dbReference type="OrthoDB" id="166529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18665" checksum="87F5BC693A919461" modified="2022-08-03" version="1">MTKQHSAQELESIATAITRQQLSLHKQLTTVKNELRSVLHDLAASKEELREAQSRLNEIDAFLDDVAVELEELQQSEDANEQHLAAKENEQEQLMMEREDEVALLVQLQNVHDLHLSVATHLRQMLVHLMRELTKMRNQEQLLAMLALRSGVFKLMRRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR98</accession>
    <name>A0A8K1CR98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR98"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="197" mass="21355" checksum="160E5A06653CD418" modified="2022-08-03" version="1">MVIRGVAPPAGAKPHTVLAPVQAPADPSASEDFFHLLSTLDGDFVLGELRADAAAFSLTFGERRVAPGAYIPVIQAGNAPTVQATQDGVFTWVLLDIDATNAPFLHAITSNIQSGTTDNQVAVVSYFPVLPSSGAHRYVSLLFKQQEVAPRDHFSGHEEEFQARRPTFDVSAYAQREQLDFVAYSYFYSTPAQPTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC1</accession>
    <name>A0A8K1CRC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC1"/>
    <dbReference type="OrthoDB" id="60813at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454613" description="Kazal-like domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="72"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="21996" checksum="9DA2B37B91413B6F" modified="2022-08-03" version="1">MKTCSIVAFCVAALAAVDSVAAADCVAGCPEVFKPVCGSDGKTYENQCSFDYEKCAKNSTLTKVADGPCAASGSGEGCEPVMCVSVYEPVCGSDGKTYSNECSLNSARCKDPSLKLVSKGECSGSGSGSGGCTTVCTKEFKPVCGSDGKTYSNECEFKNAQCTASTLSLVIEGECGGSGSGSATGRDSITSPVPAPSSAVSTGVQVVTLAAATVCASYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRY6</accession>
    <name>A0A8K1CRY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar complex protein 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRY6"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="673"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="765" mass="86662" checksum="7347F279173E029A" modified="2022-08-03" version="1">MGSQKKKAIKFIAKGHLAKKIQQRNQKKKVKAQREKRKNKYENEDGKPKKKELAVPSGNTGKKEESDMMNDMDVDEFLNGEFLDSEPESDVEKNDPAATADSDDEEDGDIKMEADDSSSEEEDEDALDPRYMTSFPSFGGDDDDDDDDEDKDDADADAEADMNDDESAAPVGRTTLTMEILIKAEKECFDKTSMNSARRMVKIFSDACRSSDAADMSKQGEIMYDIESSAVYNRLMLNVFRKMHLVFAKLVGSTTPAEGDNDNEQQKVKVDERKWKKHSLMIKRFFSCVSYVLGQTTGQDIQTFVLRELAHYIPYLLPCQKTAGRLLRTLLKLWAKSLNNNVCMLAFVRIRDLALQMPFPFLELALKGIYITYTRNTKFTNEATLPHHVLLGNCVVELFGLDIASSYQHAFVYIRELAITIRKTITSPSPDTFKAVLNWQFFNQLRVWTAVVCAYPEENQLHALVYPLCQLLFAVVRLASTIRYAPMRFQCVKLLQQIAFATNSFVPTSPVLLEILNMPPFSTSYRGAKTKHSGGSGDSTRSDLDLDLAVKLSKSQLDNRRVHDQIVFRLFELLQRECDVYKFHIGFPEFTVPLLLALNKFSSNCRIPKWNSLARGLTDSLKKRADWIRAKRSGLDIAPKDLAKMNEFLKSERESAIKKVFATDAEELKKKLETQQEANKNKTVEYNSDSDADSDDEKTKVEETKNSKKKSKKKGKKTQKEDSSAGVDDATFAKVKKMSLSEFKKSVAAVDADDVVEDFAFSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRZ0</accession>
    <name>A0A8K1CRZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRZ0"/>
    <dbReference type="OrthoDB" id="193200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="590"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="879" mass="103396" checksum="B7BAC2B497C2F3AB" modified="2022-08-03" version="1">MVRKASKLPASAKSVEEVMVERIASGAALDPRKSVADAARRRTTHFRAARKTTVAVGATVPISVASNAEPTENPVLGHLQSMDEEVSSLQSRLSSVAKSMNHTRQPLHTHQGLTNERSYHQQQIDKYIQDSMNEINAAYRGHTRRGMLTHEAGSTMDPAKGAQVNYAVREIRSTVRRLDRVFYEVATGDKQRHIAATKITALVRRFLVRRRYLRMRLALGQWRARKCALFLMYMEQFSAREEFLDTQIVRLQEERTQSWLRRIIAEIRDVALMNLPLRRRRVEETERRFLTKQRNWMKLVFATWKQCALGPRSRKTATADARARHIAARERLEALERFDVITAEMVHEEFLKENIRIVRSRHPFYLLKMTFNIILYEEYLPMEEKMMRANAHLRKKLLAKIWSVWLPLFRSVQVDKAIARVNERRTLDRFDKPFNLRKIDAHYRHTHLRKHLRAWFVYGRRVRRVRKLFEVNTKMNLVQLLQRWRIRARYQHNLRENAVEEWHAYSRRIYHTPFRAWYNYAAARRSNRQAKESICVAYQRRQRRHTKYAFFRLWKHQVLFGNIEGIHSKIHLLRSLEDQKRLCLGLEANARLYQEKIAALQHSIHELEGKVQEKQIDLLQLQDATQTTRFSIHSAEQNIARVQGMLEAVRQIHPHTIERIEKMFKENPLLTQDLKDVVALHVQKRREVMDKISLDATELEIQDATASDSNGGDRNSRRTLTREDQLLLHRVKWVLSRLDLQTYRSGMEPTRPPPGTHVPMDAMNQLCALFEFIRDGQTQALTRENDPSYPRGGTGNREIQVEDLPRVAKEDLLGHSETWHVFLQQLTVKFAQERMLLVQERLVKRAAEMNDELSEIKTNPHIYNMYSGSAQPPRPTNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT71</accession>
    <name>A0A8K1CT71_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT71"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="28181" checksum="993504A41836720E" modified="2022-08-03" version="1">MLLQIRTRTRYRHGPQDRDAQGSSGSGCEALPLDVTADDATVNDIVAKAHALYGRIDVLVNNAGYAAVGAVEEVNSEEAQAIFDTNVFGLLRVTRAVLPYMREKRSGVIANIGSLAGYAALPACGIYCATKFAVAGLTQSLRQEVAGFGIDVTVVDLGMFQTNINNANQFAKRSIPNYAPFIEHFKNITTNGDGVPLGDPAKGAQAVVETLTQTGRCEGRALPNRMPLGGNVNDLIQHVLTTGQKELNEWKYFTDAKAFAFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTC7</accession>
    <name>A0A8K1CTC7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTC7"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479450" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="102"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="493" mass="54139" checksum="9C5657EE00426D4F" modified="2022-08-03" version="1">MRNLKATITLSTLLVSTALAEDGFLRYEQEEQALEATPSVHLLATAANDVFTKILCNTPAAASFFGYKCATSDSPATNTEAPASTTPAATVSPSVTYDLHALAIGDWGVDLGLGSCCNKYRKTGVDNAEYYKDQQAQPNVAYLLAMSAEKLKPKVIIGHGDNFYWNGLGSEDVNYRFENSFEAMYNHKALQNIKWVNVVGNHDLGGSMFICGKWDNEFHECASTADLLKQLDEKFTRQANYVSPNGDRWKMPARYFVETIKDEANDVTVEIYNVDSNAATVHGGEQICCQCYGYLMKYGGDVACNNVHRGHTHCAGGDTAMFDACLSKIKEWQNDALQQLARDAKASNATWKVVNSHYSPHFHMEPTMMNDWFKVLDDVGVQLFINGHTHAESHEYATFNTHFVTNGAGGGIQSESIGSPPDYAKGVSTVWIGAGSPYGIFELSFAKQQMKLQFMTFDDNWQFKKSLADTVRGGAAIGHCWLIPVDGSKGAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTS4</accession>
    <name>A0A8K1CTS4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTS4"/>
    <dbReference type="OrthoDB" id="431378at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032432">
        <property type="term" value="C:actin filament bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21217">
        <property type="entry name" value="CH_PLS_FIM_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21219">
        <property type="entry name" value="CH_PLS_FIM_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21220">
        <property type="entry name" value="CH_PLS_FIM_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000092">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000086">
        <property type="entry name" value="Fimbrin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000010">
        <property type="entry name" value="Plastin-3 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="415"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="561"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="685"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="809"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="158"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="921" mass="100134" checksum="BD76DB1245990796" modified="2022-08-03" version="1">MSYQLHSSFLQKFTPKEIHELKRVFKEHDHDYAAAIATGDLHTVLLKMGENVTPNQVTTILKQVSLERSAQITFPEFLNLFYDLRTGGIALDAAALMDQVSISPVSATPTAPAPMATPSVAPTVEKVPFFPAKPSWPPTDAAETPVEASPFAQKAQWPPTGAAAASQPPAPSNGAAKQWPPSKSTPSMTTTTAPAGKAQWPPAGSAPAPAPAPEASSKPKWGTSSSVKAPSAKPQWQQTQAAAPTSPSKPQWPPTQANAPASPAKPQWPPSQTTAPASPPKPAAGKAQWPPASSPQRQQPAPSPQKTQWPPSAAAPAPPVASPVAPKPQWPPQGSSAPSPEPKRSQWPPKAPLNVAASTSSLPVHTSPPTPEPAAMDAHSIGVLQRRASAAAMYNANVTIHEVKGTASSVHSYSEEETAAFTEHITNCLHHDKDLSAVFPIRAKDGLFRAVSDGVVLCKLVNAAVPETIDTRAMNIKKNKQLNIYEMTENQNLCINAAKSIGCSVVNVGPMDLIEGRPILVLGLVWQIIKIQLTSTINLKNHPELVRLLLDGESLEEFMKLPPDQILLRWMNYHLKAAGHPKSVTNFSSDLQDATAYSVLLHQIAPQQCDLCHENVPEERAAHVIQNARGLGIETFIKPRDITSGNPKLNMSFVAQLFNTCPALDIVEEDLKQLEEILYDDIGDTREERVFRMWINSLGIDEVYINHLYSDLREGINLLKLFEKIEKGIVSWQKVNLVAPNTFKMVENCNYCVVLGKQLKFSLVNIGGADIFEANKKLILSIIWQSMRHHQLKLLSDLARARGHSTGEGITDSDIIQWANAKVLQAGRVQKQIHAFRDLSLADGVYLLALVHAVEPRAVNWDLVTPGHTDEDKASNAKYAISCAQKIGATVFLTYEDIVEVKPKMMMTFVASLMSVDMHRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUV8</accession>
    <name>A0A8K1CUV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001227</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUV8"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="432"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="523"/>
            <end position="530"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="98543" checksum="033CE2C9F3E57A00" modified="2022-08-03" version="1">MVKLFCAVVGVGSVFPVDIDISRTVGHLKDKVKEKKPGLIHFDADLLKLYLAREGDTWVNLQDDELEKLKNGEISDRIKSLIQEELLLDETARLDDDDYFRKTFERAEDDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFVHYDPLESESLQDTMSSISSSSVTVLDCSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQCKHDEAFEQYDHDMNNWLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKGIDGRGWKRPPVYKSPGTATMIPQQQWRGEGENMDKRTARKVHADQFQSTIREIRAEYVKKASQEQPAETPDAEMASDQIHVYVRKRPLLPHEVKKHEFDVISALGEREIAIHECKMYSDMRHKYIVTHRQRFSQCYSEQTETETVYEDTTKRLVLHAMGGGKAVCMMYGQTGSGKTYTMGGMMDYIALDLFTENVGSVDFVVSVSAIEIVGTKCFNLMRDRAKVLVCEDGEGNINLLNSSETSANSATELLTVLEDVKNQRTTEATTVNSQSSRSHLAVYINLRHRSIDETPGELYGQLVLLDLAGSERNEDTFYHDAARRKEAIEINKSHLALKECIRAIGSEDSTGYVPYRASTLTRILKDCLWSRDSRASVIATISPLSIDTEHTLHTLLCAGQMLVDAPLISTEKTDVSEHGEAKPVVLIREWDATMVREWVSGLRNGEFAKYSSKLPTSLDGRMLMRFTVARFTQVCGGNAVDAGHLFKAVRTEMTNQDKLMKARRERIVARTQKKSGLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW60</accession>
    <name>A0A8K1CW60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_001509</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW60"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002150">
        <property type="entry name" value="PRK00982.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="15">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW69353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="118" mass="13119" checksum="3906BF39AB121D11" modified="2022-08-03" version="1">MNRLTAALRPLTRAAVARPAFRAAANVRFFSAAQTFLDRHEVSDRVLGVITNFEKVDAKKVNEAAKFVEDLGLDSLDVVEVVMAMEEEFTIEIPDNEAEKLTTLQQVIDYVAAHPMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB33</accession>
    <name>A0A8K1FB33_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB33"/>
    <dbReference type="OrthoDB" id="10441961at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="29281" checksum="52C23770975346AB" modified="2022-08-03" version="1">MDVAYSLKERLDSCDSFDVVSFNDLEEDLADDVKSVGSDEQEGEWEEVEASEDGPESPEVIKEEGFEEAMKMAMAVETVAFQPQSKEMDHATESSRSEENNSEDLLHHSGPTVPIQAEESEPVSPPIVRRRSAREALRDFYLARAKVSEEKSKRYRHYSPPGNQTETGVMPIKIAPLKAPERYSVDVIERVIREENTRKARVALRAFYAQRDAERTSRAALNRAREAQVYRSQIGSGVLAASCSPLTNNWSSVHLKTAETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC74</accession>
    <name>A0A8K1FC74_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC74"/>
    <dbReference type="OrthoDB" id="410751at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280">
        <property type="entry name" value="BLR6907 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280:SF1">
        <property type="entry name" value="VOC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="361" mass="41952" checksum="133D5A9785B45CDE" modified="2022-08-03" version="1">MASQPDTIISKEEALKLIEECGNIKTLEHINLSNVEKCTEQAPVYTFYMKGLQCSRDPRLSYHFWANFGGRHQFHLFTSQKENECINGSIYLYVPDLDAIESSLESVKEELKDTKFAFERINRGGLTTIDYPREKWQELFDVSKYDHIKANDPYGNEFRLSVTPRHYKAVSAALGGELPYEGGRPAVPEGFPFVAYPVRPGVAKGIARYFEHYLGAKTVVTRQETSSPDDTNELFTTHVFCGPLQAVVFIESEAQKDSKGEYDGHHLCIYIDRFEELYHVAYNEKMNHNNYLFFDRCDTWEDAKRDQQYRILNCIDPLDKSFLWSLELEIRSAQHFRYLHHRTDLTPEEEAENDAKRKKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDK1</accession>
    <name>A0A8K1FDK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_002924</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDK1"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005745">
        <property type="term" value="C:m-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000019">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000003">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF2">
        <property type="entry name" value="AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="403"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="94"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="214"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="832"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="832"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="863"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW56999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="873" mass="95479" checksum="AF0D9600773C2D98" modified="2022-08-03" version="1">MMLVSTRRLRRDAVHAMRKQCNPRQMHILQQQFGTTLQRLGVPGAMNVTRHPALMRQMLQTTRPHSFVRNAEKKESVSDFWKWMSENIPKGFGRFYPKNGNGGKPGAPKSTPKAEGETKTLSSKSASGGNKGSNSGGSGSSGGSGGPGREGMAAYAIPLAIAALLMSDLASTEKPMQEITYQEFRSRLLDAGRVEKLVVVNNKYVKVFLHDAAPTDSASGSSGAESHEWHDPNQRGQHDFGRDYSGASQDHGQASSSSVPGLRVKPQQPQPTYYFNIGSVESFERQLEHAQHQLGIQPRDYIPVQYSSEMSIASEVLKFLPTLVLVGFLLLSMRGMGGAGGGGGGGIGNIFKVGKSPAKKIMKEDIKISFKDVAGVDEAKKEIMEFVDFLRNQKRFTDLGAKIPKGALLVGPPGTGKTLLAKATAGEASVPFFSISGSDFIEMFVGVGPSRVRDLFREARANAPCIVFIDEIDAVARARSKGQFSGGNDERENTLNQLLVEMDGFNSSEGVVVLAGTNRVDILDKAILRPGRFDRQITVDKPDIKGRREIFKVHLKGLLLDGNVDDFARRLAALTPGFAGAEIANICNEAAIVAARRSGKSITFKDFEQATDRVIGGLETNRIMSPEEKKTVAYHEAGHAVAGWFLEHADPLLKVTIVPRGKGSLGYAQYLPKEVALHSREALVDMMCMALGGRASEVINFDGRVTTGASDDLRRVTQIAYAMVQIYGMNDRVGQLAFPKDESNPYQDKPYSEKTAQIMDEEVQSIVNDAYERTKQLLNDKKDILADLAEELLKNETINHGDIVRVLGPRPFGGNKTYTEFVEESWKEADRYEADKQAKKAEEAKVDTTEQQKSEEAPATETAPKEDDKSDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDP8</accession>
    <name>A0A8K1FDP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger CCHC domain-containing protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDP8"/>
    <dbReference type="OrthoDB" id="437973at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="20988" checksum="17CFA1ED9CE03935" modified="2022-08-03" version="1">MAGRGEDAAPSAWAMRKEAKRNMYLTSTDHVRVQRRGLGGSSGGSAAAAQCQKCLQAGHWTYECKNDAVYVKRASRTSQLKNPKLRQPFNQDKPPETAEVEPEDKKKKKKTSATKRTKSKSTRKKRRSGSDSESDSSSGSSSSSSDSSSESESESGSSSSSSSDSSDDSDASSSSSASDDSRDARRRSKKRRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDR5</accession>
    <name>A0A8K1FDR5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDR5"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000044">
        <property type="entry name" value="Isoleucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000414">
        <property type="entry name" value="Isoleucine--tRNA ligase, cytoplasmic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000133">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="22"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="702"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1171" mass="133301" checksum="ECCB97F956D1281E" modified="2022-08-03" version="1">MASSSASRSLPERISFPDEELKILQLWEELDAFKKSLELSKDRKPFTFYDGPPFATGLPHHGHLLAGTIKDTVTRFAHQTGHFVERRFGWDCHGLPVENEINKKLQVTTKEQVLEMGIDKYNAECRGIVQRYTKEWERTVKRIGRWIDCENDYKTMEPWYMESVWNVFKTMFDKDLVYRGYKILPYSTACTTSLSNFEANMDYRDTPDPSVVVSFPLIDEPEVSLLAWTTTPWTLPSNLALCVNDAFDYVKVKDLKTEKIYIVAETRLCQVYPKMEKKGYKGGEFEILEKFKGSTLVGKQYTPLFDSYASWPNAFRVLSDNYVTDGNGTGIVHQAPTFGEDDYRVCVKHGVCDKFDLPNSLDDNGRFTDAVPFVKGLHVKEADDIICKDIKERGRLVSKNTIVHSYPFCYRSGTPLIYRAVPGWFVNVEKIRERIVENNRQTYWVPSFVKEKRFHNWLVDGKDWNISRGRFWGTPLPLWVSEDFEEVVCIGSIKELEELSGEKVEDLHREFIDHITIPSKQGKGTLRRVDEVFDCWFESGSMPYAQQHYPFENKEKFDAGFPADFIAEGLDQTRGWFYTLMVISTALFDKPAFKNVIVNGLVLAEDGRKMSKSLRNYTDPNEIFERYGADALRLYLINSPGVRAEPIKFVDSGVLSVIRDLFLPWYNSARFFSQSATRLELATGKTFVPSSEEALSSKNVMDSWIIAALHNVIKFVHTEMKAYRLYTVVPRLVEFIDQLTKWYVRLNRPRLKGSEGNDEARIALSSLYEVLYTISKLMAPFTPFFAEYMYQFLRQFHPNVVNNVAGLAEDADGVAKSVHFLMVPDYDASRVDEQAEQSMKNLQSVIDMGRVVRERRTISLKNPVRKVVVVSSDAATLDKLRALKTYIHDELNMRDLEFTEDEKEWCVLKAEANSKALGRRLGKALSGVRKSIDALSHDEVNSFLLNKTITIDGHELTGDDLFVKREFKGDKKIYEADVSTEGNLMVVLDTREDEQLKQQGCARDFITRVQKLRKKAGLVVQDKIQVYFAEQEGNSTISTAIKEFLSMATTTLGTTPAPLALKPAHSVTIIEEEAQFSGSSVSIVVTRPAVFFAADDVLAKASKVAVADAKAYVASMEYADVKTALTSEAAAVSFQILAEKSTFKHGEHVFLDAKEFAAASKQPELQWLTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FET0</accession>
    <name>A0A8K1FET0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FET0"/>
    <dbReference type="OrthoDB" id="10634608at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="661" mass="72583" checksum="74FC54608F48AD93" modified="2022-08-03" version="1">MATAMATTAAMGGPREPRMAEEALLDVYDLQWKAIDIKLDQLRNECERMILEYEVELKQQMYLRECEELLRTQATQHEATRRELDGKQQVVRDAQKNAERQRVRTELKEQESERVAKELKEQEKKRAKEAEAEEKKRVKEQEALEKKRAKEQEAQEKKRAKELEAEEKKRAKELEAEEKKRVQSENRKEIAKAKETAKAKPTPVVPEPAAPSTPERKKPVPTIVQPTTEEPDDLLQMLSHDAEYESEDFGDLPSMTSLILPTSPAVWSPEKPMQSKLNRLAFRPLKTKKGVQDAAKRRKPSPKPLLQTAQPESEPRPSESESSPQPLVTPQKRALKRRKIMSPGPGTSLFATKAPIASAVLNKKESDKASSAAVDPPTGAVDDASAPNMPLDTSITVRRKKGTKKVTDDSASELEGDGEKKKKKKTAKKSQKLTAAEDEAPELGGFDIKTPKVTKKKKAVAKNTEIDDLEDPQPDFEVNSSEHNESDGNGDVEPAAGKKRRREATGADAVTPKKKSKTKNRFANDELNIMKSPVPLGFRSSRPPLLADPSGDKAGKKRLASDRDGGDDDEPKYGAPAQSIPASTTPGTPTDGLAAAAADYANRWLNSGLVTRAKKNAVKTVQKTTTGGAKAASAFGGGGGSFFDAFVNTAAPRLKGNTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFA3</accession>
    <name>A0A8K1FFA3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFA3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="102" mass="11452" checksum="27C9F2079C4B0A10" modified="2022-08-03" version="1">MRGVEVICGLVETAKLEENRTQRKRKHNKVGSAVDQPVNRRWCAFVVLPVTMEPSVTMNRMAELYDSALEACGPLRPPERVYLCLVDGGIISYYQLAMILGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFG2</accession>
    <name>A0A8K1FFG2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFG2"/>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36960">
        <property type="entry name" value="SI:DKEY-32E6.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36960:SF1">
        <property type="entry name" value="SI:DKEY-32E6.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="45542" checksum="B42273B273E11996" modified="2022-08-03" version="1">MATSSTRRKVVLHFDLNRTVLMSDAAGGRTMENTVNYLLSECTWGYVHPTNPSEWVCVSEASSIAPPAAPKVTIDGNDVAVPLITYKQFVDDSLPYKSLKDAGVDGKDTIEQIKAFNKAAKKQRTALQSAFTGSGPGAPVIGSFNEVMEKLHFPSGPQREAAKDAAKSLPVSRLQEAWSEGRYYLLPSFMQFLAYLASLEDKYDVKLVFRTFGDDIPEVAKELELLVDGKHPIALETAIPASFKLTAAGAQVGTFYRDGFESDGTALAVGTLTKVPFTSAHQGDSSALETFYQGQGVEIVRGFPAIHRKVQEMTHSHPTIALRDYWEWWSAHAEAGEYGKLLLVDDSASNNDIAVFFDDHVEAHHSHIVDVRDVASGAPVPFSKSKGKYLQRVEPFAAITDPHYFINLVKSILQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFY2</accession>
    <name>A0A8K1FFY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003193</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFY2"/>
    <dbReference type="OrthoDB" id="5325112at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="23"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="480"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="991" mass="110641" checksum="DF23146DC50F7F29" modified="2022-08-03" version="1">MSSEIDFGQRAAFRTTPLVNNFDGKIECVTHYSSRVVIGSSDGRLVMFDTRKGPNTSASVTFSFEHGRPVEQLLAVPHIRMVIVVANGEISAHGATDLKPLPFDFSKVNTHQARLVCINLRGPPHFRLGIALLKKKAVMIYQYHNSDKTYKYLREFPTPETPEAMAWYRNKVIVGLRKTYVILNDKSGESQTVNSPGLQDLQSFPIVKLLPKEEALITVMDKVGVYVGLNGEPLPKNSINWTQSPSSVEFTAPYLVGLIPRVGVEIHSTADNSFVQMLPISRVSCIFSNGMKWDMEPRPGGDSEDVVIVGVRDGSKSAVLKVEQMPMDQQIGELLDRGKIEEAQDIVKKAINGLPSEKQRSKIKRFQRQAMVALLRRLEFDSAVDYMYRSAVEPCELIAFFPEFQCASFAYEPAILKPEVLPRGSSSSPDIKSVINEILEHQHTNLASEIARATPEDLQQAATKALMKFLDRYKKHMREKAQSRSRAASRARSASIASSGSNGPKDARRAEAIDTALFRLYVTFKKQKELVTLIEENSTDAEGCNLELESCQTLLSKHHLYYELGQLLLLQGKHREAVEVYARLHSGEQKQSNVPKNPVEAAIEVLIQAPADQDALVYEQSIWIMKATAVKNALRVFTERRVKMSSNDVVEHLKKNSDDPAIVQKYLETLVKSERDQYTNSTSNGNRQSQSLDVNDSYSNFLAGDNEVEVVVPTDTTAVDPHHTRLAIEYIDEVLKLVQAGEAPSKSSPGKEPGPLGEARKRLLKFLKAGSSRYDVSQLMTKIRSTPLFNELIILCGRGNLHEDAVRALVTELNDLKGAESYAVKYGVRTASVEKKTKTERNGALLELLKICFNPTDESKRAAYEDYAFQLLGRHGKTMDGKLVLEIIPPTTPLHKLAEYFSQCLPHSAHNVRETRITKSLSNVYNLQVQCERVDKLSQSVEVDAHTLCESCKKRIGDIVFVVYPNGKLVHYNCTNGKLDVCPVTGEQFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHC8</accession>
    <name>A0A8K1FHC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHC8"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="43095" checksum="F3D1372DD51A7759" modified="2022-08-03" version="1">MVNGSDAALWHLAEGISCHAWNHDRSKVALCPNSNEIWIYSGCQNPDATKWRKEAVLTEHDMIVSGLDWSPVNDMIVSCSHDRGAFVWKYDPAFRQWKPSLVVLRISRAAINVKWSPSGTKFAVSSGAKCVSVCYYQAAENWWISKIIKKHKSTVTDLAWHPNSQLLVTGSTDLKCRVFSAYIADVDGAPNPGPFPQLAPFGEPLAEFDNANAWVNAVAWSPSGNRLAFAGHGSSVHLVQFGAPGEYPTIQSIRFQQLPLNRIMFLSDDALVGAGFDFNVLLFSTDAKGLWSFNELLDKKPVESAVKRSSGTFDAARSMWQSKVTRGQSSDATLNDKGALWTKHESAITDIQAYRRSASGGVTEFTTSALDGRIVLWQLANLNVQMANLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHG1</accession>
    <name>A0A8K1FHG1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005032</name>
        <name evidence="3" type="ORF">Poli38472_014830</name>
        <name evidence="4" type="ORF">Poli38472_014839</name>
        <name evidence="2" type="ORF">Poli38472_014855</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000133">
        <property type="protein sequence ID" value="TMW57651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000121">
        <property type="protein sequence ID" value="TMW57683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000100">
        <property type="protein sequence ID" value="TMW60974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHG1"/>
    <dbReference type="OrthoDB" id="164026at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="625" mass="70224" checksum="A354E87A8E204DF6" modified="2022-08-03" version="1">MRREAALRGVPTPVADDLRYNMWIPASVLTATFKDTEILTSLGQSSQPSVWMDNCVNGNIRDFKCIKNAGISFVCTDRFICQKLGGTELSICGKKFKVQTYSRYTHWYYVDLTRLPDETSDGEIYDWFAEQGAPPVYITPTNSIRGLHSRSRRVYFPTKTTPACFILPGEKPLRQIGFRAGFCVVNHRIRAYNQSKPPFLAALQTQRQELKKQEKNEKNEKNQSKSKPAFSSSLQADIAKSSTEKKVKDGDDDSMEGDSEYNPDDDEGGDGGDFPMSSSSEKSKSRGSSFDSDSDPHSDDEKDDGKVVVNPATIWRDVSKPPPNFPSPPDQRSEITFFQVLGQRHTLFPDAEIFSAKDNFKVKVLPVSQNSYPVFATVNPFEWIASGETDDLPPDVDILLTDDNKKLIASTVKMQKRAKELLDGARTAFDVNEMSLEALSNFLEKILSELDNTESADDTIAKIQAQPCFLRPILSKTVPANYKVLESKIVDHAYYRVVSERTKSKTNARSTFAEKLKILFADQVPSDAITALQKLVEDPDEFKQQLRLAEIDLCLQVLAPGIYFDPYKISAIVQQEVTRLSNSRWLLWDDATLELLLHSDFGTNLLKTKIPTQLAKAVTEARARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHV1</accession>
    <name>A0A8K1FHV1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHV1"/>
    <dbReference type="OrthoDB" id="156308at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035481161" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="63"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="378"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="701" mass="77190" checksum="F44D23CCBADE48CC" modified="2022-08-03" version="1">MKLFLRRLITLSVAAAVLLLSVATESVRANGCGGPRVRKAWRLMSGDEKALYKNAVAKALEKNEFFEFTKIHVHHMSEQQAHNTCAFFIWHKRFLLAFENMLRSQGPEFACLTIPYWDSMTEYAQMVDGQCKSIYDCAPIVRELSGEPTQKKETVKINGRAVTGECYPGFPGYCDDSKQVCGCVPRGDLRTRAIPSSSGFQGLFDQIAFSKDFETFAKAIQMGIHNDMHSALGGFMSTFYSPNDMIFWSWHATIDMLLYIYHQCHLAESMSVDQLRGSLYAFSQDGDCKYASDAPDAVVNGQLIQISEYKGTEYQAADNPVIGKYFQGLGTDIGALLGFKDLGDYSYKYEIPEAFKKFLLLKPELCPAFTDIAVSETPAPVTSMPPANTTNAPDVTNATTLEPSPAPSQSIPAQNFTSSLRGNRPKETRDYDASGSEDDDSYMPGTVRPEDPSYEERDQYDTGASGYGRNVGYDPDVGDDDGDNTYDDKKTQPPSPAPTPTTPPPTPVLSETPAPSTTQPPPPPPPVNVVIDPALLKVDEKDPSLQAAKYWDWVGTAKTKLEQVFPGNHSEIAQQLQYLECLSFNDQFGVRNYSKQFIEDFHLKEANQKPICMKKIEEVKTGQREVVVETKKFEASKVEVKPGVTPAPPVPPRPRPTRAAIPIGDASETSSASQLATSVISVHALVLAVGLNALVQLALQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI98</accession>
    <name>A0A8K1FI98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI98"/>
    <dbReference type="OrthoDB" id="121002at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="46160" checksum="AF61E639D8F05331" modified="2022-08-03" version="1">MGPQVLTLDKETMQVIQSYLEFMKDVLDIEPTRLLYRMNNHRASPYTYTTENASGFSAVIANLFKSYNEDKSFDKTLFNSLDDAEREFMKYLLNKCKITSRGFESAYNEGLDVYVKRLKHLQGAQDIGDDNPNIKKEMLGILDTLYNKGVFTPGYYNAFKRAITNRNADGNWRTITSQRQNNTFKIIWPTASTTQAYTITLPDGTYTAQDINAYLQYWSIQNNLYLINNTTGNYYYFISCAENVSSYAIQFNMQPVRAVSGYTAASGFPTMSVTAYTPQLQIIDSGAVSFSSIVGLTQGTYPAAQTTSLYSVYSNFVPTIDPTAAVVIGISNLYNPLANNSQVLHTFTSAGVEYGALVTTSQGQGISYCPMQGTNNEIILSFYDQNMMPLQLIDPNVCIRLLMCPKKLADLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIG9</accession>
    <name>A0A8K1FIG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIG9"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09615">
        <property type="entry name" value="Jacalin_EEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="282"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="44959" checksum="AFFDFB2BCAA40C42" modified="2022-08-03" version="1">MLRALQETTGSFSVLSANVAGLPAIISSGDPATNSVELGRRLSAWDIVNVQEDFNYHDQLVQANTHTYRTPHSGGVPFGSGLNTLSKYAFTDVGGLDRVKWSKCSTFDGADCLTPKGFTYLQVKLADGVFIDVYNLHADAGTTNADLDARKANINQVTDYILANSKDNAVIVFGDTNTRWTRAGDNIGSLASRASLTDGWVSKIRNGVPPVAGSDAIACSSEQMNNNCEVVDKILFRGNRLITLNHASFNIEKAQFLDAKGKDLSDHVPVSSVFSWTLNAALRMSNAVGGPHGTPFTDIGTVPTGQKVTSVSIRAANRVDGVALTVGGVTFTHGGSGGTLTSLALNSGEFLTSIELHTDKYNDRTRIFYVKFTTSTGRSLSGGKTTANKTTYTAPSGWQIAGFHGRQGDEMDALGVIYTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJG9</accession>
    <name>A0A8K1FJG9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003825</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJG9"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044518">
        <property type="entry name" value="ARF_GAP_AGD11/12/13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46220">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46220:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="9">
        <location>
            <begin position="246"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="418"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="162"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="360"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="654" mass="72956" checksum="1FFEBEF1FD27E02A" modified="2022-08-03" version="1">MLTMERGEQEHRGYLRECFALADAENRGYLRWKELKCAVAAALGIRPSKLVLAQLFEKQITMSESDLKQLKVDRETFVATLMPRMRKADLLDDVRRSFKAFDLRSEGFISFQSFQRACASVFPHLSSETQFRMFQAADRDRDGRVTYHDFETMYLVAMQLQAQEPRHAHNTKKQLTTPRDDAAAEKEERPVRHGEMSMSNQRNEVILESPRSLFDRKTTASNQQREEESRAKQDDVEEEEDDATIKQRLKEAMERPENANCADCNAPSPKWASVTHGCLICTQCAGVHRSLGVHVSFVLSCTLDKWTIAQLRLLEATGNDTLNETLEFSVPDEFQKPHADSGRTERERFIRAKYEHELFKSSPGKTKKRAVPCSSSASSSSSSPTKESEGEATNQSIRKSSDLSSTGGQRKSVISGVPSSTGTTSNGPSGAGMIEYVGVLVIELQEGVDLAAMDINDKSDPYVIFRLGEQTISSNKVHNDVNPRWNQTLMLSWDGTSPLIAEVYDVNTITTDRFMGSVVIDGDSMQPLLEESLQNDTPKEIEALYQLLMPRIWAKNFGEHMVAGAEGMTKGIYRGITGVWKDPIKGAKEKGIEGFAKGVGTGVAGVVYRPIKGLGTMVKETARSVGMTRKRSTDASEDLVPAGCLRLKLHLQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL5</accession>
    <name>A0A8K1FJL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="534"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="567"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="678"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="927"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="937"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1337" mass="150845" checksum="822E9E8EED85DB86" modified="2022-08-03" version="1">MLYQAALGLIYLHKKHIVHGNLSSAKLLVTEQGDVKLFGFGATLEKQNNKSNALKSDAREEFSAPECIGIDPNGAYRGDRHSASFESDVYSFGLTIVEAIVKRDPFAGMTLQDIRILKQSSGFVQPAEMSDDAWTLVEQMCLCDPRQRVALGYVAEQLRRTIRTEEEMAFQTSTLAHPDTVQRPRIHDMSESGGVQTVADSVRPASQNEIFKELNQMLVGMAGNSKNGSYIEGQSAVDTVSGPVEILPLGQVPTANIPEATTTAYHQVNPQLVSLVSSRETYVLVREAVANAVLVYHCYTDWRIDAIAVIDAEEVHFNVSFYHVVASENIRVDFNLLMGEDERNRCQHGRHDKRYTQALFCEMREFEELLDLIKDQAHPLLRERAAQELKDACIHQPNRDVLRSALSERLAFVVQHLLADANETVVRCGVLIILCFARDQAEWEGLRSLEALCSDIAIRLRSYSSLRLIGELVDFQLSRMAVRGRFRGTSPPDDYVSSERSRADDLLKAAGAGNIKAMERLDQGGTDLSFRSKDDRIALLSAAENGNVQVVRYLVERGIGIDTSYNNGKTVLLVAAENGHLEVVRYLMEQGAGTQCVDSDGNSVLHVLLLREDTKEIDLLPLVKLLLERGLSPLTTNQKGLSPKSIASSKQFLRVVTLIEEFASRDERSWFIPYDSIAKVGHAIAHGGFGSVYLAKWQHTDIVIKEFSDIEQHRFMDEVEVWSQLNHPNVVQFYGANHRDEPRFIVSMYASKGGLVDYLKHEKEQGRDVTWRKLKEVAVGLSLYASARDHSLWANIVVSSDGTAMLIDFGLSFFESDSDPWVKNIEDTLDAWAWRAPEYPNLSVETPTRKSDVYSLGMVIIEAVTGRCPWSEHSDTEIREFLRAGVSRQRDECQARKWPVGGERLGRRAAATSTELMTRREHSVYGLASNGYGGHVVSDDMNTREGERSHHGAEDEDADGQSTRNDSASESSSTAHRRRKRSAESSASSSDTERNAASIASKQPRKPTYLVRKEEKELLVEEIRLLESRLELLKVRAGLPTQSEEKSLAHTVESNATITDAIHTQLLQISSVQSLVARHLHELPVNPMSMFIYLSKNLEERRTTLRGIRESKFQRAISLVQERMRFLDESKPYFTEERYVTDDGAYHCKRFEIQQFEGLESVKQLYDTLRYYLSNMEISISEMLGHVTIRENMDSVDPQIWNHRLVSSSVHGLIMEMNSVGFAEYYEQYAPMQNQEFAVVAADTVDADELYPYVPEARVRRDATVAITMNSYRSPDTLELVVVLKRCTFLKLHPPQFPLQKEVLEELRANISTWSNVMSTFLVDTVRQSRRRQQQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJM5</accession>
    <name>A0A8K1FJM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJM5"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="130"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="53599" checksum="1472C6A6B91DDC26" modified="2022-08-03" version="1">MSSSAGERKGYEAFGSFHTPPPAALFTSDNAMPDLPDPSTFLPDAQLEDRLLFPKGKSDVDALAVIQSNQKHFTIDLTRWTYLNHGAFGGPTRFGMRVANAWREFAEQQPLLFNDRFLFPYVVQSIKALAKELRLKDAEELVLLPNATAGLHAVLSSVLQQTTAEDPVVVCFSTRYGAVRKMLQDAENQLMGLHVHEEPLTLEESYDDDAVLRRLETALAQYDKTKIALVVVDHITSNTGVVLPVERIVQTCRAHDVPVLVDGAHGLFNLDLDLSTINADYYVGNCHKWFASPKGAAFLHVNKHHGVAATRKAEIAPRVISHGFFDGYQSAFMWQGLQDYSPWLALPKCIEYWHHQDISRCRSYMHLLIQEATELLYMSWRMADALEQAKTFPAHKRHAMRLVRLPSTTIFGVPTNCTTQANTSADAKHIQDTLHHVHRIEVPVKCIEGQLYARISGHVYNHLGQYERLAQAIQPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKF4</accession>
    <name>A0A8K1FKF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKF4"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010658">
        <property type="entry name" value="Nodulin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06813">
        <property type="entry name" value="Nodulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Nodulin-like" evidence="6">
        <location>
            <begin position="31"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="50731" checksum="24B89561E2DC6AAE" modified="2022-08-03" version="1">MMWTTLSEDASLNGDLEAVDMAANDRDVPRRWASVLAGVALMISVGSNHSISAWNAHLKNLLHYSQAEIALVCSMASFGAYFSVIPGYVFDHVGAHNSIILGGVLLSLVYSVLSVGIVEFPNIMHPILVSCAFAIVGQASNFGVFAALGPNEGLFGEKHRGKIMALQLAAFSAGGALFALMYHAWFDGDVSRFFRFMAITYVLVFLFGWIATYRLQSGEKSEQEPPHMTSMEEFNPAPLVPGPSSSESLYGSIDITGRTLLRDARFWLLFSTVFILVGASLFVMANIAFIVESLGGRKEQVSTMVALFSVGNCLGRLVAGAISDLVLAQCPRIYFVSLASMFVAFNHVLFLWLPASYLIVPITLSGVADGIMFASFPVLTRETFGLRHFGKNFGMISVANALGFPLFYSPIGSFVYKFSSVSVDGVEKCFGPHCFRPVFLLVIALCVVALFASLQFARRRPGYASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKP7</accession>
    <name>A0A8K1FKP7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tc3 transposase DNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKP7"/>
    <dbReference type="OrthoDB" id="8060176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025898">
        <property type="entry name" value="Tc3_transposase_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11427">
        <property type="entry name" value="HTH_Tnp_Tc3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc3 transposase DNA binding" evidence="2">
        <location>
            <begin position="4"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="163" mass="18637" checksum="3482695E472B4A74" modified="2022-08-03" version="1">MPKGPALTAAERDEIRTLHAKNVSAREIAKKLERSKTVVLNYLRNPTQYGQTKRSGRKRALTPEQEEQIYTALRQQSDKMCVDPTSKMSAERIRREFNLPLSTRRIQQLLSDWRRQARKATDQQHAVDDVEDDNATEDTPTTATETESTVQDTEELLPSSIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL49</accession>
    <name>A0A8K1FL49_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL49"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="293" mass="31641" checksum="B24A0A155C84B031" modified="2022-08-03" version="1">MAPSTTATTTITTDNKVWLITGCSSGFGREIAIAARNRGDLVIATARKVETLDDLKNIGCEALTLDVTASDETVKEAVAKANAFYGRIDVLVNNAGYTANGAVEEASAKEIQDLFETNVFGLLRVTRAVLPYMREKKAGTIANIGSLAGNASFPTTGVYSATKFAVAGLTMTLRQEVAPFGIDVTVIEPDMFRTSVITSMHRFDNVIDDYQPMIQQVFSLFSSDIPVGDATKGAQAIVEALTKTGRAEGRELPNRLYMGITTRETVAGVLARCEQELKEWAEFTEPSTFLESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLV0</accession>
    <name>A0A8K1FLV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008266</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000019">
        <property type="entry name" value="Carbamoyl phosphate synthetase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000004">
        <property type="entry name" value="Carbamoyl-phosphate synthase (glutamine-hydrolyzing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000006">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF5">
        <property type="entry name" value="CAD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="524"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="1071"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="12">
        <location>
            <begin position="1327"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1493" mass="163618" checksum="DDE6131B1AD000A6" modified="2022-08-03" version="1">MASQALSPVASDIVSNMLNQERGQLALADGTTYTGYSFGAQKAMAGEVVFNTGMVGYPEALSDPSYRGQILVLTYPLIGNYGVPSFDVKDEFGLPKYFESSQVQISGLIVSEYSFQHSHWNAVTSLGEWLKQHNVPALFGIDTRMITKRIRSLGAVLGKIEFDGQQIPLADPNKENLVAQVTSKEVKVYNKGGSPRIIAFDCGMKHNIIRYLAGKGLELTVVPYDYDLPNSTVEYDGIFVSNGPGDPVMAAKTIESVRWAIAQENPKPLFGICLGNQILALAAGAKTYKMKYGNRGMNQPCIDMRTTRCYITPQNHGFAVDSSTLPTGWKTFFMNANDHTNEGIIHEYKPFFSVQFHPEACGGPTDTAFLFDMFLEKVTGAPPKLTLLDTSLYDRPTFTKVLLLGSGGLSIGQAGEFDYSGSQAIKALKEEGVQVILVNPNIATVQTSKGLADKVYFVPVRASTVLEIIKKEKPDGILVSMGGQTALSVGIELYTNGDLERHNVRVMGTQIPAIIDTEDREKFAQKLAEINETIALSKAATTVEEALAAANEIGYPVLVRSAFALGGLGSGFAANDEELLNLATKALHGAASKGGVKQILIDQDLRGWKEVEYEVVRDAKDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSNSEYFKLRSTAQKVVRHLGIVGECNIQYALDPHSERYCIIEVNARLSRSSALASKATGYPLAYVATKISLGIDLVSIKNSVTKTTTACFEPSLDYCVVKMPRWDLKKFSRVSNDLGSYMLSVGEVMSVGRNFEECIQKAVRMVNPNLDGLNAKVVDNESRPDVLEDRLKHPTDERLFYVMAALDAGYSVDKVHDLTKIDRWFLSKLMRISLLRKAIPSYSLSTMDERFVKTLKVNGFSDRQIAAELSGVTEIEVRNKRKQLGVRPCVKQIDTLAAEFPAQTNYLYMTYSGSEDDIPKSEDGVVVLGCGPYCIGSSVEFDWCAVSAVRTIRELGKPAIVVNYNPETVSTDYDESDRLYFEELSLERVLDIYELENPEGVIVSVGGQIPNNLAMPLHHAGVNILGTHPESIDGCEDRNKFSALLDTLLIDQPRWAEVKGIESALEFSQNVGYPVLVRPSYVLSGAGMIVALDAEQLEEYLSSDAVKLSSSICISKFILNAKEVEFDGVAKDGAIINYAISEHVENAGVHSGDATLVLPAQKLYVGTIKQVKRIASSIAHALNITGPFNIQLMARDNDVKVIECNLRASRTFPFISKTFDLNFINLATKAMLGLPVKSVPIALVDIDYVGVKAPQFSFTRLHGADPTLGVEMASTGEVACFGTDMHEAFLKALLSAGFKMPKEKKVLISIGHELIKREFNESALIFKQMGYDIYATPGTAKHLESIGVDCTVLYKPLTKEKMNQGLEQKSPHAVEYISKGKIELVINVPDGTNRDEISAGYLIRRAAVDFGVSLINNVKCAVLFAQAIQKVRKLEICNISEYYAMPTVGWRPGQKLTARKMSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMC2</accession>
    <name>A0A8K1FMC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMC2"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF34">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="48"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="553" mass="59813" checksum="59B784A2AA460FCB" modified="2022-08-03" version="1">MMALDEPTPTRRKDEQDDVTVVEDIKELKQAVHDEMEVIGCGFFQRRVVTILGLGNVADAVEILAIGYILTVYEDTEGKISPWESSFLTAAVFAGMLGGGFLGGIFGDIYGRKPVLLTTLTINAMAAFLSAFSTSIYWLIFFRSVAGLGVGGVVSSLFALCLEHVPVSARGRYVTILCSFWMVGSVITAATAWVMLGNNSEGHRILNISWRWFAAVVGLPSFFCLMLTSWYIPESPHFLASQGRIQAVNEVLQFIHDVNDSPKRIEYRFADAEAGLQSTRQHQPSGRGSVSSAVFDGDRLRGVGRLFHQPQLVGTLLLMLCAYCLSFGSYGLSTWITKLFQAVGLSNPFANAFLFAGANLPGNIISLYLVDVVGRKQLLSGAFFAAACSALLFAFNVEGSATVVVFVSCLFNACTTAAWNAFGVVSAESFPLEVRTTGISIVNCTGRLGAISAQFVNGFLMGPPPHVVALLLVVTTVMVSGGLAARAVRAPEEGDPAAQQLRRVALQTQAEEKRKQLESSRTLSSEYCDDEDDYDDAIASVDETKRFVGRTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMU8</accession>
    <name>A0A8K1FMU8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMU8"/>
    <dbReference type="OrthoDB" id="118200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="36538" checksum="1A8607BECBF47384" modified="2022-08-03" version="1">MASSDMTLSGSSVTEVFPSTTSRPLAPQDYLYNYTLQGGTCSHYSRVGNTGCLQPRSCSDCLLKQGCMINQFGQCVDQVTDGYNPGMDFRLAQEQGLVMPPATPPIMYNEQRWHFPAFGAAYCQASDLTCESCRQANFWFTGDFFLSDSRYCIGQDGCICVWSCETSARAYHVSEDCSPIYTPTWNNYPSSTASSFSAIAIIAIVVGISIILAFLICVANRRYQKQQARLATRQQELRQAAQTEREQSRMTAVFGLPSLNLSGWIQYRRDLIAKEHSQFEQTVDITLQGPDPSAYVSIEEAELDVGVVAAERHRHHNLQHPSSQVTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN80</accession>
    <name>A0A8K1FN80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN80"/>
    <dbReference type="OrthoDB" id="45342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="60061" checksum="9726B561F11813CF" modified="2022-08-03" version="1">METPTMLDLNDLNVPFIAATALAVSLAWTIHAFRQTKFHASRRYRALEMPEKTLPVVGNILDIVLNGDRVHDWVLENTVRVQGRPWKFNLLGLHEMIVVTTPDAIEEVMATQFTNFVKGKFQIDILSGIFGRGVVMSDGERWYHQRKTVVKFFSAKVLDLFMRQSIQKNMFRLHDVIEQAINTRERIDLKELFHDFTIDTFVEMSLGVELKSIGATEHHPFNEGLEVASNIVAGRFQRAEFVWKAERFLNIGDEGKLKHHMGIVYAWMHEVIQQSVERSIQAKQSGVASMDKKCKSLIELFLEHSEEDREGLKEEDFVDFILTLVIGARDTTADTLSWLFYALSKHPEVEAKLRDELKRELPSDTSTYLTMEHLKPLVYLEAVIKETLRLYPAGAFIFREAVEDTVISGDILVRKGQHVVMPTYTIGRNPVVWGSDAATFRPERWIDEATGQIKPESPFKFFTFTAGPRICAGINLAMMQLRIVTANLLQRFRFDVDATNDGSYRMGVTLTMKHPLVALPRMVDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNN5</accession>
    <name>A0A8K1FNN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011134</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNN5"/>
    <dbReference type="OrthoDB" id="123181at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="78"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="54584" checksum="B3E977274FFA19E0" modified="2022-08-03" version="1">MYLGFMSLAAVFLEYKRYESPEHVGWSPDESSGVIDASLSTDSDFTLIKTPRENRPSNYIAVEVSEAGHTRFFKPMTLAFKDLWYSVSDPKNPNGASLDLLKGISGFAVPGSITALMGSSGAGKTTLMDVIAGRKTGGSIKGQILLNGHPASDLAIRRATGYCEQMDIHSEASTIREALTFSAFLRQGSDVPDSQKYDSVDEVLYLLDLRPIADQIIRGSSVEQMKRLTIDVELAAQPSMLFLDEPTSGLDARSAKVIMDGVRKVAKTGRTVVCTIHQPSWEVFSVFDSLLLLKHGGETVYFGELGAKACELVKYFESIKGVTPLEEGYNPATWMLEVIGAGIGNTESDDTDFVSSFKSSKKKALLDERLARPAAIAGVMVNVVFFLLMGFNPPAKAIPAGYQWLYHLTPHKYSFAILSTIVFGSCPGQGDSSELACHRVRDFPPSVSANLTVKEYIEEVFLIKHSEIWMNVGILVAFIVFFRVVALLALRFINHQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP04</accession>
    <name>A0A8K1FP04_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP04"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="30578" checksum="8398E21DEB3E0019" modified="2022-08-03" version="1">MAPSANDPKVWLITGCSSGFGRHFAIAARQRGDFVVATARNIETLDDLKKIGCEVLTLDVTADDATVNDVVAKAHAFYGRIDILINNAGYTTMGVIEEASTDDVQANFDTNVFGLLRVTRAVLPYMREQRSGTIANMGSSVGFAPYPMFGIYGATKFAVAGLTLSLRQEVAGLGIKVTVIEPASFETAGSRNIKVFANQIAGYEPVQLFILDTMSGGLVTADVAKGSQAIVEALTQTGRCEGRELPSRLPIGPGTYEMFQGTLDTAKKELDAWVDFTKAEAFAKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP17</accession>
    <name>A0A8K1FP17_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP17"/>
    <dbReference type="OrthoDB" id="64243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="600" mass="68161" checksum="F3D52936D10ED9E2" modified="2022-08-03" version="1">MGHWAGTTTLRASPVFDLLGQVTTPRKDALFLESKMNTSFSGCSAPLFARNIYNASFLGVLSSALIRDAAYNLTFLKTMEVILPIVDCTFPTVVSGAGSALRIFYLMRNKTKTDDVALLTFSASLQDYRIPKQRQSGAAAVATISLIWDMREAKITQYFAIAQGYPFQAVSFQVYTLLGNTVEHEWILESIPSNPLMQTPKELYTSRRTGFYINTEKEQSNVLSRYWAMDDDPMSIITQIRLQGGPVLWDSWSWVHFIHLLFMVDTLANVLVLFVVTYWNIRAGKIWIGDAFVTVSTTLPYRAGLILLSWMFNGFWTLFEFSFSFAGSVSKVQDIYTCIDIMHADLFTLFLGYSSLAGVLLRERIDPALTVLTFEIWFAYRVEIARKLPSTAHVLTQFAKKDYDLSTKYLTGLSVLPSPMGLWTIHPLYSRSPHLMFVALLPIFSSFTFILIFIIFRKIYRRIFPEKIVMEHGSGNSTSNYDQLDALKLNLTMFEVATGAELQKRVGVMSDYENCVYIKGVTYASADGIYCNGYVIANGKYLIATRDIWTIIMMKIVRMRFKNVYAYEVTGTTVQQTARLVYPETIAWRDLMRLNVSMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPF7</accession>
    <name>A0A8K1FPF7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPF7"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="50"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="175"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32672" checksum="0F8D1FC0A6AFB43D" modified="2022-08-03" version="1">MFQTREVSCKFMARKMSEGAGASVHRTIGPYMPSQIDPLIMLDEFYVGLPGGFPDHPHRGFETVTYVLPTSEGSMIHEDFLGNKGELRAGDLQWMTPGRGIVHAEMPASKVPVNGLQLWINLPKSRKMMPPRYQEIKREEVPHVFNEEKNVEAIVFAGEVFGRKGPIQTEAPVTYIHFILKKGAKLEYRIPEGHNVFVYTLKGEGEIAGQSTEAHTTLVMEPEGDGIEATTSYENGVEFIAMSGLPLREPVASHGPFVMNTKEEIRQTIIDYQTGTNGFENAPHWESEIGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQE7</accession>
    <name>A0A8K1FQE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LSM1</name>
        <name evidence="8" type="ORF">Poli38472_001500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved with other LSm subunits in the general process of degradation of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">LSm subunits form a heteromer with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQE7"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="133" mass="14821" checksum="4CAC9F4CBBCEC8ED" modified="2022-08-03" version="1">MDAQEMGLCMGGLGWLTLASALRVLAEKILVVLRDGRHLVGYVRSFDQYSNIILEDTYERHVAGGLFCDIELGLNIIRGDNIVLLGELDEDKERDQPHMKRASMEEVLEAEERLNADGASSVREQWGFDAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQI2</accession>
    <name>A0A8K1FQI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQI2"/>
    <dbReference type="OrthoDB" id="58231at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23701">
        <property type="entry name" value="At1g26750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059242">
        <property type="entry name" value="mS23_dom"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="19241" checksum="0E60D9CB5A460653" modified="2022-08-03" version="1">MGRARKTSVDIIRRVKGLARNGGIRTPSWVPLVDRYPPPPTPRQDRDRLPIITFPQDRLAELYIKRQPHGLADEETAYEFADEQLTLIENGIPEEDAYQMLLEKYTQVDAHRFLDKFAKMRGIQFADPEEYDDLEREWVEAESRAVKDAMRLEFEEAEEFRQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQR2</accession>
    <name>A0A8K1FQR2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQR2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="237"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="515" mass="56159" checksum="ADC957966B38C745" modified="2022-08-03" version="1">MTSYTLDDLTNLNLKISNEDIDAFINSTANKIASGLKDANNAINGEETTTQPPTKKPKPTTAPPVRDEDELEDTPKPTSRPMTPGPGVTNSTTNSTAIARPSNTSVNASSGVNAKVNAADTEVNKSSPYVVPIAIAACVVAVAVIGFVVYKRRKTNASVAKTLSPRTGRTHSSNNGTIVDDSTSEYNNMADSSSLRVAAKLSDTASMRAAAPHAKPTASALIEDPEILAMRLPMEKIVLETRIARGAYGEVYRGMYKDEVVAIKRLLPERRKDMRQIDSFLGEAKLMATMEHEHIVRFVGVAWDSLAEACVVTEFMEGGDLRSMLTRFETTERRVQGFDHDKIKIAMHIAHALTYLHSLRPIVLHRDLKSKNILLNAEFDAKLTDFGVSREIADMTMTAGVGSSLWMAPEVMLSENYNEKADIFSFGVVLSELDTHRMPYSHAGERNGGNRRLPEPAILQMVSLGRLSVEFSPSADPEMVALGKACVSLEPSERPTAAEALHRIHQIWRNAGATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQV4</accession>
    <name>A0A8K1FQV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_001980</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQV4"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="6"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW69824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="160" mass="18356" checksum="494C257DB857A850" modified="2022-08-03" version="1">MSDDSIAVQRLRQERKNWRRDHPAGFWARPVTSDDGSLNLMMWQAGIPGKTGTDWEGGVYKLSLSFSEDYPSKPPLVKFVPPLYHPNVYPSGTVCLSILNEDKDWKPSVTIKQILKGVQDLLDAPNMSDPAQREPYMDLKNDPELYRRKVRQIAVKNREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR39</accession>
    <name>A0A8K1FR39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-serine dehydratase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR39"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06819">
        <property type="entry name" value="PLPDE_III_LS_D-TA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000026">
        <property type="entry name" value="D-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="6">
        <location>
            <begin position="312"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="429" mass="46327" checksum="A78B8AC0D819DE3E" modified="2022-08-03" version="1">MTAAAMATAAVVVGRRVWTTQQSTRRRLMSGAARLDVMTRRRPANIGDTLSAVETPCLVVDLDAMEKNLRAMPKTLADRKLSHVAIRPHAKAHKCAEIGHLQLHYSNAVGLCCQKIVEAEAMFAGGIQDLLLSNEVYGQDRYERMAELAKQGAKITLIFDNEETIHQAEAVAAEAGVEFQALVDVNVGQNRCGVDSVEEAIDLAKIINRSKPLTLRGIQAYHGGAQHIRSYAEKEKVILHQVCEKAKAVRDAFVTNGLCCDVVTGGGTGTYLFEASSDVFTEVQPGSYLFNDADYARNLGQNGKFVQDWEQSLFVLSTVMSVNKSAPRAVIDAGMKAVSLDSGVPLVYSAIDSRPLPPLTYQGGGDEHGILVPAPDAPDSEIPMPVLGQKLLLTPGHCDPTSNLYDFIVGFRNGVVETVWQIGARGPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTD4</accession>
    <name>A0A8K1FTD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTD4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="104" mass="11437" checksum="E5796F48C5980D52" modified="2022-08-03" version="1">MVTTTRGSRTTAVADEEEVVDAGLMVEEEDEVEVEDVDGGVEEEGEEGTTRTSTSIQGTSSAVVISRTVHKTLRVSSCRPSSKIHGMLCFYLLHRLHRMLQIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C237</accession>
    <name>A0A8K1C237_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C237"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="200"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30616" checksum="8E42AC884725E318" modified="2022-08-03" version="1">MTEVTMTTSVEAMAVDEQRHEAVETSAAADASLLASEEDEMERVLLRDERSCIFETRVERAALCRDRGSAQFKLKNVEKAVEWYERALYHVDFDEGTWHFEFMDQHRAAVNEVRLPVHLNLAMCYLGDAHQNLEKVIEHANEALVIDPENAKALYRGGKAHLLTGDLDGARTKLKKAAQKQPNDKNIREALHLLAEKTAEHRAKEKQTWGGRLLETKPDDDASDDESDNKTQPDNKKKAREDSPSSGPRPNETDDSNSSWFTQLRRSIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2F9</accession>
    <name>A0A8K1C2F9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2F9"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="112"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="47609" checksum="9863E1203745B3BE" modified="2022-08-03" version="1">MESHATKRSTTQLAWQDVLGTRLTQEDEVIADPSSLDENRAYYFEFVALPAKHPTADKPSRRVLHKWLCSFPQNALKEIQELLKWINFLADPRSTEDVARAHSFDDLVLVERPPRRFLVVINPISGAGKGMKVYQKKVAPAFAYAHIITDIQLTERAKHGVDIAKQVDPSKYDAVVTVGGDGSLRETLQGLMARPDWQEAIRMPLGVIPSGSGIGLFAAKMHAARELFVPVSAAFVLAKGVPHPLDITVVRNPFGETMYSFLSTTWALFADVDLGSEHLRFLGLLRFTITAVNRIVFIHRAYQGTIWYLEDDETRGYQPQPYDFERSTDRPGLDLVGAVEEGALAADGSGGRWRKIESSFHMMAVMSISHAATDVHMAPGARFNDGYCYLIMLNAMHSRKDLIKMVLTAERGEHVNVKSAEFIKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3J5</accession>
    <name>A0A8K1C3J5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3J5"/>
    <dbReference type="OrthoDB" id="166091at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="282" mass="32129" checksum="A154ACD2F08AFBD3" modified="2022-08-03" version="1">MKPGAEEVSTVPWDELLQHQSKACSTLDHLKRVSSKRHARKDIAAASDVSDSVHHEMLELAHHTELAQQRGRDKVQVADMTTLGERFGRAKPQYVPGTPIVRKLKGGRMIRLDGKDAPGSLASSRSAPALSVAQSKQDALDRVIEETKSPSRAAQQGDTTLRMREDPVTSQLQVQQQQLEERLLQVTQKLCRKYSKQLFPAEPVKHTIAERAQKWSQPEAMSEDERYHLYMEARLSTQHKIDYNRHELEPREPAYDRHRRHTIHTKYGDALARSRPGLRGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3T8</accession>
    <name>A0A8K1C3T8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3T8"/>
    <dbReference type="OrthoDB" id="66690at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="41362" checksum="5F540CFD341D8DCF" modified="2022-08-03" version="1">MASNDENDALRAIEAQTTDVNITEDQYEVLTCCPSQSPVPGASVVSLKRRNTGAVRSCANAVVSAVERAMLRSLAFVLYHLKHDQARYCVNAMMQWYRHLHAQLPHFAVSVLESFATSLTALSDAEFARFWLALLENTDEIVVPKTPLSRHSPLLLAQVPDLELERLELEEPSPSLLRSWYQPLLTRFHSLVGFPRGAIESSATSLKFSRRTQTPLTSPSDPFDDSYYRPIRRTNTLTQLDDQITLESGINEQQHDVNAVMEPGWAVQYIEAESRVPTEMTRRMQLMMHSTVPLNLFRVEVLYPTAHDDDDDDDVASSLRFLGAVSPESFPPTPITRDLQTRRIRHYTATVLDHATLALRLLETNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W7</accession>
    <name>A0A8K1C3W7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3W7"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="234"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="483" mass="55204" checksum="9FA625CC8867EA86" modified="2022-08-03" version="1">MGAYKYLEELWKRKQSDALRFLLRVRAWEYRQLPVVHRLNQPSRLDKARRLGYKAKQGYVVVRAAVRRGGRKRQNAKGIVYGKPSHQGINQLKAERNLRSVAEERAGRKFSNLRVLNSYWVNQDATYKYFEIILVDYSHKAIRRDPRINWIVNPVHKHRELRGLTSAGRKGRGLRKRGHLANKIIGGSHRGNWKRRNTLSLRRYRTNDSNLVSKRLAPTRQPDVMEGFNCCRCVSYYDEMNPERRKTMEDTVRIVDGFLQRKENGFFAIYDGHGGRDVSVYLQKKLHENIAEELQMDDTRTVEQRIESAYLITDIECCQTVAGSSGSTAVTAILLQEGDQKTLYTANIGDSRAVISHNGQAVRLSTDHKASGAEEMSRIIKNGGFVIQGRVSGVLAVSRSFGDRELKQFVPARPYTTATSLTDEYLFLVLACDGVWDELTDQEVVDLITRLPPHDHPRAAELLVKEALARESCDNITAIVVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Y3</accession>
    <name>A0A8K1C3Y3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tropomodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Y3"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053040">
        <property type="entry name" value="LRR-containing_protein_71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46984">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46984:SF1">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41292" checksum="3BA659DD9047FF2E" modified="2022-08-03" version="1">MPKTERTHAGIWSVEANNARFQQLSNVNELVTRIMPTQAFRTDLLAFYDATRLLPHPQLLPFHPDEEEPSANPENGGNGVHYELKNIEILTIKNWQIDQGSFRGMCFALEHCQLIHTVQLFNVQLSVEEVEQLCLLIPQTAVTVFHLEWNASFSKSDEASLPPSAIDALLSPSSKVTALSFRASGLSSVHADAIAKALRANTTLQVLNLFQNTVGDEGALAIAYALPFNSTLKSLSLGNTAISGKAARVLVDVLTKYVAPPSLLQELEEAEPRIQSELDQAKKAKKKIDRATAMQNLGLPLLETIDGEQYAPGNSVIEDLVLSGNKDIQEDDLTAMNAMLETHHAKLEQHLKRIRLQRIPALKAVTHPLSPLLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4A6</accession>
    <name>A0A8K1C4A6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008726</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4A6"/>
    <dbReference type="OrthoDB" id="79871at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="111"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="588" mass="67294" checksum="9FD132133F4434CE" modified="2022-08-03" version="1">MATLFGDLPSAGPKSSSRSGSISGGSGGAGSERALQWVFDEDTPNCMLCNTQFTMITRKHHCRRCGNVICHNCSPHKRRISATDPFPMRVCNTCYAAVDEHFASLEWSGHSTTDVQTKADPVIEGRVHIGQLYVKVVEAIGLPSTDSITSDPFVRVILTGKWSHGQEWGNDVKSIKCTKKKSRTLNPRWHETFVFNVCAPGAELVFEVYNYGQLSQPTKLGEASIPLSQLMDQRRHNKWIDLLLPEKLHRAGLNNDARAGRIHVLLHYKFSRMAEFCSYFSAEQKYVHEWPEFQAAHLYSSFWVLLDDLWPYLEVIWQIIPTLNWEHPTHSFMCFALCVWLCLSLQWVPVVIHLALIAFTLRNYFELNLNSFAVSDAKEATATLDGDNMLQFRQYNLPTGFNHLMNKMTHVTIDHETKRTLQSVQNNMAWWSTIFHSLEMMFSWEDTFYTAKVLLLLIISCVLHIVVPNKYLLLTLVVYLFVRWTVPYQWVAHFVWALRQAIRSLIHQQRLRSSTQPSDILASRDNMLASTGKRKSFDKSRSRRSMSNASTRSHHSVSKKEEMFGAAASAISERFVVNGERVQRKKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4L5</accession>
    <name>A0A8K1C4L5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4L5"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005371">
        <property type="term" value="F:tricarboxylate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000078">
        <property type="entry name" value="Mitochondrial DNA replication protein YHM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="15"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="102"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="198"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="30540" checksum="BB29989B345D561B" modified="2022-08-03" version="1">MSPPAAQPGKKVGPRDLLNGGILQCVEAATLGMPFEVWKTRMGRYRTETTTQAFRNVMRDGGGVKAFWAGTGPKMVESASKGAILLFSKEAIANSLLAAGVSESATGFLAGAGGGVCQVVVMGPCTFLVTAAVTGDKSITTSQRVSNVYKAHGIKGFYPGGTAIAFRQATNWASRQGFTEIVRGRFKLFFHDDPNAKLTVAQEAGAGIIGGALACWNHPFEVARIQMQSAADRGEAKQNMVQVFRTVVKEQGVPGLFKGIIPRVGLGIWQTLFMVTGAKLVKQALETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5S5</accession>
    <name>A0A8K1C5S5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein NO VEIN C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052957">
        <property type="entry name" value="Auxin_embryo_med"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024975">
        <property type="entry name" value="NOV_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387:SF0">
        <property type="entry name" value="PROTEIN NO VEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387">
        <property type="entry name" value="WU:FJ29H11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13020">
        <property type="entry name" value="NOV_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein NO VEIN C-terminal" evidence="3">
        <location>
            <begin position="2663"/>
            <end position="2755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="584"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2549"/>
            <end position="2621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="341"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2568"/>
            <end position="2577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2779" mass="311144" checksum="4C99E73C4BAB824D" modified="2022-08-03" version="1">MKEDTTPTTSQRPTLAPVAAISGPALPRRRTETLSSPSIQDVLTRLPRDVNVSTTTSPLMIARQDGTEGFQNIYQPHISIQPVALRQEPQRKAETPPQNSSQGEPSEASLEQEKINHSCRVTWCDRPGKRYGLCWTHGGGLEQDVVTFVNGLRASRSDPSAPPNALSLYAVLQAICAHFRVGTYEELMGSSPHQLPVLRQIQIQNERVWSFVTCYTHARRIHTLHECHLAFLQHEGIRQFSDLGIGNAFVLTDAVQSLYGAPTHIYRITTMDVLQTFRQFERVVGQDVFNNNGPPHHGHGPARVQHVDRNQFKQFLAAQHRQASAEVMGVYIDAEGFGAYIGMVRRVARREQKEIQELQDEFNKGIADRVFELSKEKFSAENRQQALEELLERTNEARSVEQTRTGAPGTSGEVAAARRTQRKAAISSMSSLSLEILNRVTEVDVYLDNVLRWKSTDERHKTRLAAQPIAENDLKIRNQLTRFLLATQKSRHHSRIKVVTWVLCGVLAKIHAVLQLDDKLPDETMEDDGESQSTRKPTTDAKDANDKDEDEGEECDCCCVGLDTCKCQCDCRCHQDDSDEEDVASSKVMAEENPDPVKNSDEHTVVRQNTSKDSVGCSSPRTVQAPPATDVEQELIRFVEEKMTQSKPTSIDDVLKLLAAAEDHLLNKFKVESPLSVLQQIVAKLKEVTNDGSKESPLDQFVECIRLFQHTNATSGAVVAAPAIDMDEAHAFISASLASPSVSVDAVVIAACVQFGLSSSNSATRTVLKQVVQDVQAKPDTKNSNHASDRIVYSRAILARESTEDVSMDGENELAMDQMVAGKTSEALARLAMCPFLVDVDEWMQWPVRYERFCGPLRRFLRSHEVIPAPTVWDDHAEKSANGLRFVCCTNGRIYRIREDATPSMLDVHLDDLTPTNLAVDLVSIVAQYGTSGADFPKELVLLHLRSLFQQFQGAERKSRSSRFVLEMLSLVPRDFVAFVYDLVKSAIQPISIDEAIPLVCQSDIERQSLLVLAENVGCPTWASALIQISSNSSSQRTVNDQLHEQAGISTPHQPSPSPQLDGCSQSTSHAPVASTELIVTSTKSQLDPSECKSFIAQLRREQFGIDLEVVDPTTSAVLAVQHRRLERALKRLSDELYSEKTHFVLELLQNADDNSYPEGVSPRGTFVLTDDDSILFHNNEIGFSQANIQAICDVGASTKEQQTSSQVGLVLARSIGKKGIGFKSVFKVSDTPQVHSNGFHIQFYAHDEQHGHGLGYVLPYWIEDTTKWKTEGGTTLLLPLNEPSRHRRQEIAASLLSFEPSVLLFLQKIRELRLKNSVTSSHQVFKKEERVVSVDDGVSLVTLHAERFEGGVTQQKQQRWIVVKSTLKVPPVLQQLGQHRQQTEIAIALPILEDEDLTNRPPLQQVFCYLPLRSYGFRFVLQGDFEVPSSREAVVDGSEWNQWLITQFPTLFTSAFRHLEGLGVSLSSILRLLPVDNEIQAPFRSMVSDMMRVIQALPCFKVAAGQESNASPLAPACELLDASDCWSIDGDSDDVAFLAETMVKTARALPKRLMDPRLSYELSSMLKAQLRVEKLRVSHILRLLSGVCPLRDVRVITRLLHILAMLWRREQHNSQSALWRQELRLLRCFPVERSEDSDDCWRSLADLRDVLFLPHSSRRVQHGDGAMARMGLDGAVPIMRSDMVTLLESESAMETRHFLIVQVGMKELEAHHIISHYVLPRFATLDLDADHPVWTDYTRYLAEHLDSCVNCALSASIRRDIRLWTCRNQLVTATDATMNVLVVFPAMMRRYEALVTWLRHRVMVNKPAWDLLFVDEDLEESNAIADRAVATWRKLWVEVCELTDLSDVATRSLSDTLAMVVGWIEEESDVSLKRRVSAQLAALADTNWLSSVEEQGTEDVKLAWWRAAKWLEGSDGGFHEPSALWVPSGETERLSLSSLDVPMAIVRFRSSTLISSWKLRMKPTIHDVLDVLARLSRSKNQQAVKLSHATDLYAFLLDQNAAEKNPHTTSVIKDAFSSTNLIAVAEEGIVSNWVSIQDAVWSSGDAAAAFMACHALDDSYPKSLREFFVDVCGVARKPSVARLCKAFEALPGGAMSSTEWNSSVFPILRELARQLKKKKKLTGSELRALDKTLTKQAWIPIVDHDSDMLLVKSMKTLKKGAVVFAQDDDERDIQKLLLGLQKESPGGFDKRSIHVMALDKDAVNDLGGLFEHLGVLSIHEGLMKDEVLWLESLAHVGRSCYSDDTTQATKTLRRKRKKYEKLLQRILTHWASAMSDDSANEVFRSVDVQAAFSQLTLFPVLNHGKTDSTGSRLVRGVDLFVNDQSELTKEAIASASSHSSSLQVIGLFEWDHFLENQNTSMLRLLVDCAQVRPLSQYLKSEVVVLGMQRAVSPFFTKKIRQSMQIAQRVMFYQYRRHYDALDHSEMRALLARLQILTVAGADEALQVVHRVANFAMRQSVSCVLEKHSGTLFVHVRDGEHADEQSQLFTALRELCRKFFGEQIATSVANVLYLASLQQSEAQVEAWLSSTQNMPPLHAQCGSLWIENEGDETGRGQAKKKRPVQDVDTLEDGELAGDSEYTAPPAQKRWKSEQVTTQPSPPPSTWAPSNARHSMTSYPPPADQGYAVNNWQPGSRPPTPSHLVSVGGNSMTDEEKLAIGRWGEEYVYQQLLQRYDDDKNTRVEWVNEKAESGLPYDILVSTGTSQDVEYIEVKSTRTMEKGVFEISMNELDQAGVHGSRYCIYRVFNAGNAPLCRVIRMKNPIALVRQKKMQLLLVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U1</accession>
    <name>A0A8K1C5U1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Crossover junction endonuclease MUS81-like HHH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U1"/>
    <dbReference type="OrthoDB" id="115877at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Crossover junction endonuclease MUS81-like HHH" evidence="2">
        <location>
            <begin position="157"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="290" mass="32228" checksum="A54212011454528F" modified="2022-08-03" version="1">MNLRQTQRVLAELITKCQEAHVQLPVDPFESMLCAAEALRHSRTGQNPHIDDALEEVKQRYGIEPTWQQHLDDEAQKQENRRKRGRLQKTQPRTRSSVKKPSNTKRAATSETDTTGSGSDTGKKPKKAKKETMAPKGATDSKRVQSIIANNPAKNSANQELANEFVELGGLELAQGQTQKGISRMTVAKQLRNADEPIESGAQARELPRVGPSAAAKIDEILKQGKMAALQEYEDEQEEERDSAGSGAENPDLSIESEDATPEDNEDEHDEEMEWEDDGENGDDEEDEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C608</accession>
    <name>A0A8K1C608_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C608"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000880">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="11">
        <location>
            <begin position="31"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="603"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="639"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="746"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="782"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="844"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="884"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="927" mass="106119" checksum="27837B49761941EB" modified="2022-08-03" version="1">MEEPMELEATEFSVEVGARVLVFGKYAGTVRYVPERRSALVGIELDRARGENDGEIDGQRFFQCKANHGIFVREENISRFSNEDAAACILQSMWRKFRAAQKFRTLVFSHAWNLLDNNQEQLNLKRSEKFKSAEHTLSMLSNRKLVRTVSEMQIASIAVDADYKGPHISWPLKLANVLDLLEHFKRGEVLHHKYVLEILKETIRIFSPLPTLQDLNLVQGEKLTVVGDLHGQLQDLFSIFSINGLPTQTNKYLFNGDFVDRGAYGTEVMMTLLCFKILYPDAVFLNRGNHESRNQNSWMGFEDELWSKYSGVMENDPERPAHLFERFQSLFECLPLCAVIQQKIFVVHGGLFSRDNVTLAHLKAISRKREPPLHQTGYEDKIYEDMLWSDPRSIQSRQPSERGAGVEFGVEVTNNFCLVNKIALVIRSHECVQEGFEILHGGRLITLFSASRYCGTQMNKGAFLTLGPELQPEIQQFYAHDINESTFKESEMQEALEDDTLRMIAERICDHKASLFWYFTQHDQEHNGSVSRLVWSEALRSVLQLDLPFLTYQAKLADADDSTGMINYSRFLARYRIENEAVDQNGWQESMIGMICKKLYRAMGAGNLEQAFKIFDSDHNGFIEYEEFMGMLKKMDTGLSDQQIFELMRTADTNDDGRIDFSEFAQRFEVIFTDLRQAPSSPRSTGSAPESSTSSMPPATPTSLGTPALFRRYSSREEKSFTPTPATHLDVETMDALLQIGKALFSMEGSLYYHFCHFDLNDDGVLQRDEFEQALVKLGFDFKPDLMNRVMAAVDTDGGNSIDYKEFVTAFGVQDAKEKEMLDKGDNLTWQHSVLQQVSNVFYQHRIHIRNAFRMFDKSNTGYISKDEFRVGITAFNAVLNSPLTEDQIEELLMHLDSNQDGVVSYKEFFDGFRVVDVRIAEEEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C618</accession>
    <name>A0A8K1C618_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C618"/>
    <dbReference type="OrthoDB" id="90180at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15254" checksum="EC784A8FA962C750" modified="2022-08-03" version="1">MTMEVSAAELLVGAWESTEAFGNTSLDWSQALKEKAATLVVTFHRDGAYELQLHANNQASDDVTSQFRHLVPANGTYSVESNQLKIKGDTSGIQWTFQHEEDNTLRIRLQGAKRFGRCKGVDVIYFKRRSKGDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C658</accession>
    <name>A0A8K1C658_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C658"/>
    <dbReference type="OrthoDB" id="165498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="32"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="41509" checksum="52454639C5F6F72B" modified="2022-08-03" version="1">MALTDAHAARELARYGAVRGTGRTQTLSSRGTVERSASMRGQYDYEVVFTEDRLGLTLKCHSPDELDEDETPRTVVKSTSETARHVHEGDILISVNGQSVVNLNFRDVRRLLKVASRPIRLRFRTSAENMLRYRDDSVAVETSEASYSTEDGVDSNELSSFVLPLSSDSDEEQDDDDMDSHHAVVSESFGDADSTRTTENSSILTDITDSDLKLQRHSRFSFLRKPFRRGEGVQLRSMEMHAAVIPDMPRVELALESPVKAALRVYWKEHPAAVASQVQYSRDRTMRVWKTWSGRIRRSQDNDREMLTMIYGLDFGKSYVVRIRYEFARPQFSSGEWSTPSAPVVTLDPGRIEMLRSAYSRARMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C684</accession>
    <name>A0A8K1C684_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C684"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF29">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW57095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="46999" checksum="788D9137732BDB61" modified="2022-08-03" version="1">MPVEVQRKLTVLGYPGVGKSSLTTCFVENRFVENYDPTIENTFHKTIRFRNAHFVTDIVDTAGMDEYSNFSQAASVGVHGYVLVYSIGSRTSFDKLKLINEKLLNMLGSRPPRVLVGSMSDLDKARQVSSEEGQMLARQWECPFVECSAKDNENITEVFTYLIKEIERDSGLLDVSNDTGCTILHRRRRMMRKVTFELGRAVRETGQALDRLGLRVLGENSFKERFSRHRQIMNLYDKAPMIAHDVWVAPNATVVGDVEICNDASVWYNVVIRGDLNQVRIGNRTNVQDRTVIHTASTSTPGLSPGTSIGNDVTIGHGCILYSCTIENNALIGMGSIILDGALVESNTIIAAGSVVPPGRRIPSGQLWAGNPAKYVRDISDDEVSDITKQAKEYKGIAQTHSDEFLPYGTAYLDAERVKAAGGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6C8</accession>
    <name>A0A8K1C6C8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003292</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6C8"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="810"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="489"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="897" mass="99546" checksum="7596EC9480879F92" modified="2022-08-03" version="1">MPTSVKLPPSGQRPSVVQTTSRPQSATPVLGIQRRQWNPPPLDLFPTEPPKRTTRTPRTPKAHAVAQPTPPSSARTPVESVSNKQVQPRASVVNLSPNRPRTTRRESLATADLGKEISPQRRASVVSEAQLEALQRGATKRMSQVTWARLHKAAIDDAPSDIDMSDRADTKTNADVVHNQRVDSVIAERRDAIRSALVTKSMKKQGVDTEDIRPLIEIAYWSPFLEVRRDAAAALASLSRNPANLDLLSNVGALGALLSMLNATDNKVDPAIARDCAQAIACMVKLHSVKLKLLQAPDGIECIFTLLHSPDFKLRTIAFELVKNLVTIEDLRQAIAKREGFAYMLDSCRSKDSRVRLLAASILNNLAESRENRFLFYHSTHFQTLADILHDPFLEKDVLFRRELLSFIQLLVTEEDNGRKFVELHLVPTLLLIVDSPRSNHAICLLVVSILESLSRNRRNHSALVTANALPRIVQLCFCGHRTVLSLGEITSSPGSPPRRARPSTAGSTFSRRTTRVASPPVASHGGDDDIRDSDNLKIPVGTQPPSTLRASVAMSAEMNALLRPAFAIFCEMAKNTVNRDHIIRSKLIDYIAARNLYASSDKRVRRSVITLLTALICKERERDRRGSAKCTPTLDQRSITGGIDEEVNSDTLNHQQDSDARNTNTATASQETEFKHYIELLARGIVKCLFGILSGNDFSMKVDAIAAIAQLTDDEHSRLTMCKPQLLQSLKEFAFHPLIQTRTNIAKIIANFAERPENILKLVDEGMLTILVKYVCPISRNNDVLVEATRAIAAMSKVHVTRNKLVECGVLGTLIQFSKSPSTTSEVRTYAAAAIRNLRHDAAALLIQSIYRGWCIRVHHARAILTRKRRIRRMTSIMKIQTDQAIATVMERLVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6D2</accession>
    <name>A0A8K1C6D2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Signal peptidase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6D2"/>
    <dbReference type="OrthoDB" id="29558at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009582">
        <property type="entry name" value="Spc2/SPCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06703">
        <property type="entry name" value="SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="193" mass="22130" checksum="32D89BADC9CE8232" modified="2022-08-03" version="1">MGGTQSHKRKEEDEYEEEELVENEYHVEIGDQNAVKNLLDDTINEFFQEHKDYTVQYGWDNVKLLLLVLAAGIAATAQFYRSPMITERVLIYSCVIGFFAIHALLLAYTVFVERDIAVRMTGKSSSSLLVKTSFPHTAENYTVVIEDAANPGHKAKAELYIGKYFDAEGYFDRDTFLKHIDALRMQFEKQKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6L9</accession>
    <name>A0A8K1C6L9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6L9"/>
    <dbReference type="OrthoDB" id="1924189at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1131" mass="134277" checksum="4594B60ACB3B258E" modified="2022-08-03" version="1">MGQTFDIESSPSTSGLIDLFVNWSALEKFQQLQDSSVLYAAPRGRPKRLKALADYQIPEPEEQLRPSLTAEEQEQLALPRKPFRSEKEYLKPLYATLSVETRSTGRLQAPFIAEILNVLQSSPPAQTVRMAVSNDLLVLHIVAVHEVRKDEIVVHFQRDQMCPIDELCKLRDAYVWQIVRFHPKKAIYKLPHGENDTTRPPRWLRDVLRFVIHPTMDFSASRQRHELSEFAFFRVHAALETVEAIVEATFWSHSIDWWHHMRTCDLEELVFSKKYGALCHSHPPSLAIDSLKFSKFLRECELQPRFLSVGDAAFLFATHRAPGSHYEMIYGGFMKALAHIAVLVYGKQDTIVVDHNEIIRRLFFEWLIRAPSMREIWMELVDSWRLVEKKHFMTGAARRYCAATRIRSVWKRYVTRCRHVEAMKRLKQERLAASKLQSIYKMRREQGYYLKLRTCTIRVQLFIKARRYLRHLRAKRVLYVERMRVRLVKWMRQRLRVLRVWKQLNEMWLARRARIQEKRSRLVSSGVFQLDSRRFRISLYHVLRMENQDEREYDLEMLDPHSSWWQSVRLTPKQLEQLKTTDVTKNRPKYDRRLLDITRRLYLKRKRNEFRLYKNPLETSLGRLVFHGAVRLNASSSTDWCVFRALLRLHDMTVISYSPRTSTLVRWDFSTTFVYRVLQVTHFNDLLLTQDESQKPESLEDRTRMRCVVFDTLVSPDTTLDVLRRLIDYLGLRGTTQPTYEMQPRVIAERELARQRTMALECERQRQRELTLVTRVQANARRLLARRKLRQVALCSYVKHFDRHLASFVYILLRCRRDYWLQYTSKPPSLGTTDIADPKDEWILAEQLEHGAMSFFNPLRGVFSRISDEDAARLIQSWFRRVMWIGIQRWDLRYVSTTLRFHHNTRPPTDMNDPNELEYIVRHSFDLHVLQHDFKTAYTVYESALTIAPIDVRLLVGLAIVLVYTCHYPVKQSWPRALALLEHAQTLENDLVSSLEEMESKYFGWALLLRPKCLHAIGTYAVYLQCVRHEFDKAEILYRRALDLDPSNEWILENYRRLERERTPTGVYHFSGGPGKIAVWRSQEVRRLPNSTWREMEDQETRCPATRRFFHDTRTNRCSWTEPNDARVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C784</accession>
    <name>A0A8K1C784_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003237</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C784"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="71"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="221" mass="24789" checksum="CA51E68BCA0E1BC0" modified="2022-08-03" version="1">MVPNKFRTQRRSFGDGGEHRQSVFDSADRVLFVLIGTNLVVTTLWSKADTHLRKAMMVAFFTTSIVHLEKGNYHTVFTSMFSHVDLSQLFTNMLGLYFFGRDISHILGSKRFLGLYLAGGVLSSCAALEEQMRSRRVSPNLGANGAVNAITALSILLYPHTTFRVFGILPVRSWFAGSLFIGRDFFDWIGKNRDALFASLASIGCGGLYYVSMLRNVRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C793</accession>
    <name>A0A8K1C793_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein intermediate chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014348</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C793"/>
    <dbReference type="OrthoDB" id="4189at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="387"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="533"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="690" mass="75609" checksum="0B31683F0B6657F0" modified="2022-08-03" version="1">MEDRRETVRARHAAELEAKRKKLEEIRRRKANIRTGEEGVATESVARAIDEQENKFDDFIQNILKTTATGESESEGASATTTTTTSGSAHAVFSLAEKLAALSTVGNVAEVHIQPTLVETYTKFTETDITLEHEIVVRDYQSVTDAAMDESSPHSPRNRRQSTDAPSTSPSGKLRSLTIETDLSLGGDVSMGLSDEEKKKIMQSDAMESFLLKASRVIERAMTSSSKFDIMVDYGATVEEDHLPEESAESLKQLFTFKDDQWTKHRAVTDVDTSPFYPELMLVSYTSRDFLEEEEKDLLASTKQWDTMANSAALADLSRTTEGVVMLWSTALPTRPEYRFTCHSQVTSACFNPFDRNIIFGGTYSGQIVVWDTRAKSAPVQKTLLSSGSHTHPIYSMSVVGTKSAYHLVSASTDGRVCVWDVDQLQQPLEMLDLRIAMSIVSNYSSVNISSDKKMEASVTSFAIHRKENKQLYIGTEAGKLYSTPLDQQKSKAVTVGPDASGIDGDKAARGVIGVSNGNAAAREVVVNPFSKESAHFGPVTAIHMNPLLPVHRDGLLLTASLDSTVKLWSTEHPQRPVFSFEPSNEYVCDVRWSPLHPALFAVVDGSGMVGFWNVNKDVEVPVLESKVSEKALNKVRWTADGKNVIVGDASGQTIVYEVPSEISVPHADELSVLESKVASAVVAAGINRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7C0</accession>
    <name>A0A8K1C7C0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7C0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="70" mass="7955" checksum="9C5681BF1F9EB3B7" modified="2022-08-03" version="1">MALSKRPHDANDGGERVEDENAQNRLENVVSHGDVHVLKRLHREFATALTQQDGDRAMRQAVRQAVMKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T3</accession>
    <name>A0A8K1C7T3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T3"/>
    <dbReference type="OrthoDB" id="427998at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="38305" checksum="5FC29717DCA0D582" modified="2022-08-03" version="1">MYVQAEGINQNVRPAQDRCVCKSNMHNIVFYEVPIVQTNETIAEYQDSRDTPEYGPFVTMESGRCSPQEDGEFPPECYMFNGEKGYPNLGPFVGGGKHNDSRAPYPDTHWLSFPDRCPTELWGPTKFGKCRQNTRRGLCPIGTAPDGVTCTFTYEILGWVPIDDLVGISNESYIGGKYENFTTWCKASDDHVEFAGDVKTGEMEKGLDFWKNPTDPEANKERAAKVIQLYDEIVSGKFVSSMIWSHQLKRFKPLPSPEELTAKNTKCYESVKCCAGGCVRTGYAQLCTPCKAGESGCEAADTSFSFPSLEKVKSEGEDQTPALSSAMSVQVTVASIALLATFATLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7W0</accession>
    <name>A0A8K1C7W0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7W0"/>
    <dbReference type="OrthoDB" id="166900at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="27918" checksum="E7A7B44951CECCB6" modified="2022-08-03" version="1">MNADEELVERLNFISEFSCAVTFLLQITIIGYDLNMKIRFRTVRVLTRVSQLLTIIDLIEIVRALLSIFFPTLVHEEIAELFPTVCENVTLGAIFVFRLYYVVISSGWPDLWMNRKLEVTLYLLFALHEIPFLILENASGLSWEYAQALWERVTLAGCLYITATNKLRGPGGSRSSDRYKSQEFRRASAQRPSILVVKTASVQRMSASQIVVPAISDRTASCDSIKPSSALAAQVYSKSPGLNSQILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7W6</accession>
    <name>A0A8K1C7W6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7W6"/>
    <dbReference type="OrthoDB" id="113361at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="32163" checksum="D227CBCC0CB9EBE6" modified="2022-08-03" version="1">MASSSSSSSSSQRRRAPAADVNALRRIGEALLLAQNRARVSTERANQCERLLRSVLSQINLQSGALLHELETIPRSMSLDALSDWELLHSLAHGESSSPSAQFQFPVLDSDPHPPPPPPRRQSLSTSESQTFALTMTPHALVHAASSDSAADVRAVAFDVVMNLHIAARNAERRILKMQQPRADVVMVRRRSSWFVLDGWLYRWVSDSVRPWHFVAGIVVGFVLGVSAARQTMQRPSSQHSKPRPLAIAHCRAEMSTDPRMKKLRLAASRLPVAFAVDDMSHLLYPTVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C830</accession>
    <name>A0A8K1C830_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011762</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C830"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="478"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="586"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="647" mass="69914" checksum="5122F4073FE80739" modified="2022-08-03" version="1">MPGTTPAIVPTPTTASSSPVAHPVRLRELWLLAVSMTISGHFTHWHIALLTVDVLSATAAFFALAAVFVVMVLTTAELNSVLPYAGGAYAITRRTLGFTAGYVVGTFSILVHLFYIADAVVTLVRIFVENASALQGLEPFLWFVTLMSMAILYRRSSRVFWGIVTLVGGSSLAILALYCLSALWLYRRSQAEPDPTRPKASAAKFLKIFPLPGWMFLGVEALGTITDLGNDNRVLASRAQRAYLYSLLLTSIVVFALSAALPPHELTSPLPFTQSFADTLGLSTPHASLLSAPAMYVTAYCLIGSCARILTSMASSGLLSRRLYRRIQRSESRTRDPSRKRTNDSALGTVCVVSYLLCLIAHYAKTQILFTVCLGFAFVSWMLQLVTYVTIRLSPRILQHAPYRSPFGIPGALFALIISLVAFISIIGGQHDGGVEDIVMASVGALLLLYYHYHIKKHQLMSSRERDLMLAILGNKATKSKPKPTPAAPARAPAPITVPAPSPEPEPTPASSVAVIAPAPGAPVDPSAPSPKLPSRPSLRRLPSFPEGEVVDMDVPYLPAAESEPVATQEPTPTLSPPPPRRAKTDSNVQTASSPPVATTGPPALSWGRSFFRSTGLERLREETERDLRSAVSGIWPSERSSHGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C891</accession>
    <name>A0A8K1C891_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C891"/>
    <dbReference type="OrthoDB" id="147163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="21862" checksum="F6C179905D6DDD36" modified="2022-08-03" version="1">MKSFLANVDIRSIMPLIDITNDSCFPSAAVSRQVKQNGGEKNEGAITGNCRNKKQFYDYSNTYHRYACKAPGNKKHAFDHVIVWTTDGKVTHGSTATLGPKAAADIPKDGQRLKFVYYKNTNYSFRFAKNGEAVQNPYGKYVSLVVDSWYPLPGAIIDGLNMFDYSPAVMPIKNSVFLTKSTSLVQRDTRSLTKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8L4</accession>
    <name>A0A8K1C8L4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8L4"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="784" mass="89933" checksum="FC7F497FA869F9CD" modified="2022-08-03" version="1">MSPRLVRALFSTDWLQRLLLPLLSHEEKTHLVLVGVAAGFESLRRDKSAFPPISNIELVQIAAEHGWWDAVTVLQRDCRLAKRRFKIDHDGDKPVGTYKDPMFLQCQWTQRHHPVEFEPNVMYAAAKRGRLEEVKWLHRYTEYHADEAILTAAKACHLDIVEWLLDHHRTANQRDADGWTSYSIVMRREDSFLDGISWCNNTTEVTYCVLPKEGFLPPAYSRRYPFMDWAAQYGDLELLKKLNSDPELRQTCSSDTIRSAAMRGDLPMIQWLFKHRDEHRRLLNLTVQTAAAEGHVAVLEWLLANTSMPRSTTDIDLALTGGHLEAVRWMFANYDESLFRPYALSHLAAKSGNLDLVRFICQEEGYNVTFTTVEYAAQLGHVDIVRWLVDFDRDRVLPNAVYDKSLLEYAASSGNLELVKFCVEELGTWSDTLAQCAAPSGNVDVLEYLLAKAQERATAKGASLTSEINFAPVKIVRMLKVRVAEEAVLWVLNHTAEEETERQRARDAKHFLAPFKDLPSDRMPSWRVMQALMLRRPKLCRVIGLFPEWAIRRGTVKDLQTLEAIQHPTLFTKATLDCMLKYSRDAVVMSWFTTRCDSTLLDVRVASWIATYGVTELLPVVVRKLLVQGEDLLQVFGTVIWSAVKHDQVSVLDWLKTQAYLSKLSDELWRVCVAKRAARGGQMRSLLWFYKNEKVDRLQMNALTGITAQFGQVRCLKGLYEALAVECTYADLAKAARRGHTDVVEYILQRQTFIQADCEQVMCEIDHIRLQYKRFMAEDHAKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8Q6</accession>
    <name>A0A8K1C8Q6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine incorporator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8Q6"/>
    <dbReference type="OrthoDB" id="5963193at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429075" description="Serine incorporator" evidence="7">
        <location>
            <begin position="18"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="45769" checksum="64F9A3503FBC6B58" modified="2022-08-03" version="1">MTRVVYLALFFVNAVLAALLREFGKLALARMSSILHVFKECDPYEDQGYCFGNQMVYRMSFSLGCFFVMTAVLSCAASRGCENACCLMCVQLPVYFFIVVGSLFIPNSSFETYVDVARLASSFFIILQIVIIVDWAYNVRDFLLDQMEAASHDEEARQALLTSDYDNLSLTEKSSSATAWEAAYIAIVFVLGAGSTAAIVIMFKWFSGCDLNVAFIILTIFAAVVITVLSVLSWVNVGLLPAAAVTAYLVMMCYQAVHSNPDETCTGTDLSTISPHGKSVLLNATLAALTITWTSWRTSATNTKLFTLTPFATTETKTFDEQDVKDLADIEAGEEGDVVNSNPHAVPEYQFHILMVLASFYMAMTLTNWGSANGLDTDDDQVATMWVKISSQWVAAAIFLWTLVAPAVFPGREFGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA75</accession>
    <name>A0A8K1CA75_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA75"/>
    <dbReference type="OrthoDB" id="2383523at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="46748" checksum="F1F204B849512208" modified="2022-08-03" version="1">MTDRKRRKLADALGRFTTSAEELRALSLALTSAVSEHSKREVATLRIYPATSSSSAATTQAPKTATSLVSLVPITQLRDASDLDKAKEGDNWKIKAAQLARSLADSDPDAVDRCSRLIRRYESLAGTVSVYEGRLKQQSNEVTLTEKVEHQLEREEKAWESQMQEREHRVAELEVELSALKRSTEEEDDDEDIQQEVASTDPSESVTAENHSLQEALALRMEEKRDIEAALQSLRRKKRRRSMAENTVTETETALLSELDALREEKEQLRQGILKMEEEQERIEAEQRDVAALKTTMVERKAERQRVQEQLDKQKLLLSRMKSKMKHMVDIQLLTARDTSPPTLKEEAVILHLLYEHAGEMGVNELKQAATEFLAQFGKVNASGVVIRALYSLVANGVVQIDRTYGSGHVTSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAZ9</accession>
    <name>A0A8K1CAZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000904">
        <property type="entry name" value="ABC transporter A family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000298">
        <property type="entry name" value="ATP-binding cassette sub-family A member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="514"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="586"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1052"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1257"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1318"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1350"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1385"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="669"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1530"/>
            <end position="1764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW59991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1934" mass="213754" checksum="5A226A0B2CFEB16A" modified="2022-08-03" version="1">MRKNWLLKKKRPVRLLFEVFTPVILILLLAWIKAQTTEQNYLAGFGGDESDNDLFQPYGYTPAGSSYSPRYAIPETTLTGLLLYMARLSFDSNRDMQTFGDEKARAICERELVYGGRISLNKSSSYAVPSECQDHVSLYKLAIAPDNAFTRAYFFDTVKEWYPTLEINVTSNATLVVPSLEDSVVFYDTEEDLENYIKSATYGKTMEQPRIFGALVFNEFPGDASIGSYAPIDYSIRMNGTDTEVGFISHVPSTKSGDASTWFPFRRGVDTAAYKLYASGGFMTLQTLVTRFVNCMPKWDSKAKVSTGECQASSSLASASNDLDNRLLQTVKQDPSTKRALSELMGDRGMDTTIVKANSFDLPLSKGHREVLLKPLRQAPQPYLGATTSPFPSAAYSTSDFYRTFKSIMPLFFTIAYQMVLSKIIVTLISERETRSRELMKILGVKESSLVISWYLTHGLILLVSCIFQALMATSLLFEESDMILVFLFFFLFSLSFLAYGFMVSSMFSKARTGGYVGIIGFVVMYAVSNAFNDMSSESSKNAASLLSPTAFAFAIQVLSEVETAHVGIQFSNASALVNRFRFSSALWMFVFDTFLYTLIGMYLEKVVPKTHGTTEKWYFPVMPSYWRRRRGDMSNESRTHDETAVHMEPNVEPVSADLAEQERTGAALCVQGLSKVFSVPGGEKVAVDDLQLNMYSGQITCLLGHNGAGKTTLISILTGMLNPTAGDATFRGLSIRRNMDEIRESLGICFQHDVLYPELTVEEHLQFYARIKGYSGTELDNEVTHKINEVGLSDKRKTISSALSGGMKRKLSVAISLLGDSSLVFLDEPTSGMDPYSRRSTWEILMNNRHNRVLVLTTHFMDEADILGDRIAIMAEGQLRCCGSSLFLKNRYGAGYNLTIVKEEGCDDAKVCDFVLGHIPGGRVLSNVGMEIAFQLPLETSAQFPSLFNDIDANLENLQVRSYGISVTTMEEVFIKVAEAANDEDVSGHQKLVLGNSMKTHKVQTMDSGELPILGSTDSPVVKSKPTSMFALHLIALVQKRYRIAKRDKRFGFVSLFLPIALLVSGIALLKAGTLSKPNLLMPLSIDSLQLQLPSYCDQPSEDWCNKVFSSSDFTGGAPVILGTNDIGNPPYANNSPTVLGFQYYSPSFNHTGTTGQLLKLTQVIYDRAIEQGVDNQFGGFLVHADSKSRVLSYNVLVNTTLDHGSAVFKGLMDQSIYRIMASEASPSVDVSKLYLKVNNYPLPQSVLPSAPFSSYLGILVCLLIVIAFVFFPAPIVTLLVKERQAEHNSKHQQLVSGVNLLGFWLSNYLWDLLVYIIPGGIALLLIQVFDVAPLSGSSDCVSCTSETFPAVVVLFVLFGLAICPYSYSLSFLLRQHTSAQNKAITFNFLFGLVFIGLSLVLELIPDVQVIGRALKWVFRLCPIYNLGNGLLIIVSMEMARNGATPFETAPWLSPFSTENAGYEILSLGVDAVLLFGVAVGIDYARSFPKVKSMFTKKPSVESFEEIEDTDVVAEAKRVATGQADGDMIMLQNLRKVYPNGDKVAVKNLSFGLKRGECFGFLGINGAGKTTTMKMLTGDIVPTSGSATLAGFDILSQQIDVRREIGYCPQFDALIDLLSVREHLELFAQIKGVPRSELDEVVREKMQQLNLTAFEHKLAGSLSGGNKRKLSVAIAMIGSPSILFLDEPSTGMDPVSRRFMWDVISEISTYNKQSTVVLTTHSMEECEALCTRVGIMVGGGLKCLGSVQHLKHRFGDGLMFDAKLLPAPVSEVESLVLRHFDSLDARISALELSDVCRRFGESAWEEKLVETHPTGFLVASALRRDGYVLAGSFASWWLTEVRFAGVERFLSSNFARVELLERQNESCRFKLHDVAIGDRVALSRLSLGHVFGLLESSKASLAIREYSVSQTTLEQIFNTFASQQHAENPMDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCG7</accession>
    <name>A0A8K1CCG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCG7"/>
    <dbReference type="OrthoDB" id="66500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="193" mass="21869" checksum="9C2E552A7D679520" modified="2022-08-03" version="1">MKMMAPAHESDGDALRRAFQQLCGEYEEIVDDSAEITQPVDERIGLAMFKIDEATAVTELVRQEALETQDEVMEALLENCRELEDIFIRVNLMESFVNKVHATTKELEKRLDAISRVADPVFNTGSVSTLLRSLSIKRPTTEAASPEVKWEPLEFDFNTKQFVERLKRTNAEELGVSIDTHVAKAEDKAHRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU6</accession>
    <name>A0A8K1CCU6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCU6"/>
    <dbReference type="OrthoDB" id="71691at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452030" evidence="4">
        <location>
            <begin position="27"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="46856" checksum="2B4AD926574DE595" modified="2022-08-03" version="1">MVSVRSIARVLLVATLASSAVSMAAADDVVKTEPKVATQTEESCLAPSVVAQLETQLDELKQTNAEWAVKLEAATGAWETEKALLVEKIAEKESTHEAATQALAVAKTDAEAKLVAVEATLKEGQSEHMEALSALQKQVAALEATVAELKKQLSSEKETVVQRNAEVSEARAKLAKVSTQVKSLERDVAQSRKNNAALRDELAKMDEKLTMAALLSSYYDEGVVLASKTVTALQEQIAQAQNGTSSLSEVLTTIEDTKKTILESTDKLYAEHLAATLDPVIADLRTATEPYVTEYRPVVEAELTKAQQAVADLYEVGVARAHATRGDAVTLLKQNESVAPYAQTIVDGSLVILALPIAFFAIRLALRFVWWVLSTVLCVATFGFCCGKCAKKRSKLKRKMSRKQLTTAAKPAAPAASTQSLNGNGSATRRATKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDC5</accession>
    <name>A0A8K1CDC5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDC5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="23685" checksum="AD3788F7CAD1904D" modified="2022-08-03" version="1">MLVEVEGNLMTNMPVALRFAYATLVMKRRWVDGHKPSVSVDAPYAIPPTVATSPQKTTACETEEAGAMDLLTPLMAFVLETSATTANLHNSDVMAKVACELRAFARDHCLVTEVVRALTSLFDNDLPTEMGNRLSSAASQVMLCFESRGSEGELIEYMPTPECEQILEGLIALLVHSVSVPDEAISTVSITRLRQVVEVITTRLEASNEPQDQTLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE45</accession>
    <name>A0A8K1CE45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE45"/>
    <dbReference type="OrthoDB" id="77799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Chromatin target of PRMT1 protein C-terminal" evidence="3">
        <location>
            <begin position="138"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="26852" checksum="2FE6D51AA12650F9" modified="2022-08-03" version="1">MQRRAGAQRGNGNGNGRTSVKSQRRVNQQQAPRGGGKKQNKENGQTNKGSRAAPIGVSGVSLSSRFQTLQKVALVDNPAPKAKAALKKKSPVVNVKKPQLRAKTPVVRTAKQQQKAKKQEIQQKQQKQQQQMKKVADANRTKRQQTMNSRRKGLEVAAPDKNAAKKTSKPAAKKAALAKGNGASRGRKGDDKKKEKPVTGDDLDVEMEAYWHAAGKGPDPHAARLDRQMDDYWAGKPKPEGESEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE75</accession>
    <name>A0A8K1CE75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE75"/>
    <dbReference type="OrthoDB" id="105025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="45806" checksum="0962BA48343ED95E" modified="2022-08-03" version="1">MKPRLPKFALPSLSLTPEEQQAVISECETVLAETLAHERSFRRGETTPDKKEWKQVKAREGIRIRKERHPNHSSPSDVTAPRFLSLHDDSVSSIDSIDSNEEELDYVTSIKDPRVPMVITTGTVEGTLEDVIFGSMASDEVSWRLRATYMKDKTSDSKILATIIEPTEADPYKCLCIKWFMREIPGYLSPFMHVRDFLVMEAAGIRVDEYGERHGYYIMHEFHHPSLPVLQSRKILRCGISQAYVSRQIGDKVRMFARGFVDPRGEVPYNISVQLTTATTISVTNCVETSYTKKLGWLMMREEDRRNDPEEPQVVPRSECSCNKSKAGLTCRVCSASFCSRCVVQKKIVVDMRDSDVIEHVLPFCFACVLSAKQMSPHEVAVDTVDRPRSFLQSSSASVSQPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE77</accession>
    <name>A0A8K1CE77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE77"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="6">
        <location>
            <begin position="81"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="34759" checksum="D127E0810B081B33" modified="2022-08-03" version="1">MAVMTITLVPMFWCEVRGVTEMREHPALRNTPDMPQVADLWIAVVMALGIIAVRYVLVRALEPVSRAILPPHLRDSAFRIDRLATSLFNAFYFSWVSIVGYIILKNEEWFPASLGGSGDFDQAFKVFDIVPTSSAKLYVLLQLAYQIHNLIYVLLLKPLDNDVMDFVVHDFTAILLIGSSYLTNYYAIGATIGFLNDACDIAMFTFSVSTDSERKPVIAVMTLTILVVWGYTRLYVYPLEILSGVFTESPKDNPNLSPLFFWLMRIMLSFLLVLQTWWLVLFAEKGRRKLLRPTVTTQLKQIVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEE4</accession>
    <name>A0A8K1CEE4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_010738</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEE4"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF5">
        <property type="entry name" value="ARGININE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="12">
        <location>
            <begin position="11"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="11">
        <location>
            <begin position="494"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW61675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="626" mass="69542" checksum="9E81BE10CD3DAE20" modified="2022-08-03" version="1">MRSRAALSCTGQLERLLHGALRRARPSLDLQAANLKLPPALGVRRSQQANADYQTSIALMLGNRFREAPEALAQDAIAGLHEEQDGNTAVVEQAFVSKGGFVNVVLKDAWLAQHVVNMATLGVQPAEYSKEHSKSILVDFCAPNYGKKLHVGHLRSSVIGDTLCNLLEFRGHRVSRISHTGDVGSAFATLIVELIEQKVSLETLSDAQLGQYYESGKKKHANDPAFKAKVDDVVIQLQRIGSSGTRTLDPVVEKTWQRACEVSQAAYAEIFDRLRVNVKERGESTYLPLIPEVINELKARGLAVESRGALCIFVDGPDKPPMLIQKQDGGFLYATVDLACLRSRIFGFPGVDDTQHDEVIYVTDQSQQYHFQHLFHVAQEAGWLSRPSHPKGDVRLTHAWFGLVLGKDGSKLSSRNGAFDYLEDLLNEAGAECQRRSVLANDTRADGGESLSSLNQKIGDAAVRYFDLAQQRERNYKFLFDNVLNLKGNTGVYLMYASARLQGILRRAREQEPALRRVEDWNELLTLADARGLLSEASKDWEPSERALALLLAHFDDEVSATVAQLSPHYLCDYLFRVVGQFHSFYEKCRVLGDAKQDSRLLLCAATHAVLQRGLHLVGLEAIKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF80</accession>
    <name>A0A8K1CF80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Myosin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009839</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="90"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="624"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="660"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1378"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1449"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="902"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1289"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1386"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1456"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1495" mass="170469" checksum="46F71B3CADD03983" modified="2022-08-03" version="1">MAPNTTESTARARGQSAALGLSIGTRCYIPDKERIWLPVTVEQVNPQEQTATFVVDPEANDGSEDEKSIELSLAGQVHFPLQNAPARTPGGYEDMIDLNHLHEAAILYNLKRRFLARLPYTYTGTICLAVNPYQWIDELYSHGLHAKYLAARSQKQLPPHVYAVSVAAFKHMSGEALNQSILVSGESGAGKTETTKILMDNLAQIGVSSSADAEQTTIQRILDVNPLLESFGNAKTKRNDNSSRFGKFTQLQFHRKGQNMVLTGAKCETYLLEKTRVVTQEAGERNYHVFYQIFHGSSAAEKGEWGFLADEPITNYTYIADDDANMSAKDQRNFERTKHALSLLGLSSEEQNALFRVLAGVLHLGQVVFEPNPDNDEASHVTESSVMVAADLLGLDTTEMNKALCNRTMKAMKEVYSVPLTVQQAASSRDALAKAIYANVFSWMVDTINQSLSAAEEYVDNAIGVLDIFGFESFVHNSFEQLCINYANEKLQQKFTQDVFKAVQEEYQEENITWDHISYADNSDVLALIEGKMGIIALLNEEIVRPKGNDEGFVGKLNTAFRQEKKIIDFPRISRTQFSIHHYAASVKYEAIGFLEKHKDALLPDLSELMRGSTADFVTRLFEKKEEPEEPASPAPGRARRNNAASADSQTVGTQFKMSLNSLMENIQKTNTHYIRCIKPNSEKSTTKIDEDMVVNQLRCAGVIEAICIARAGYPNRMRHKEFVTEFDIFLSEEERNLEGDELRLCGLLAERFKLKTPEEYQMGKTKIYMQYGILERIETLKAEKLFAYVAAIQAQWRGLQQRRRYRVMYAALLLMQRRSRGFVAVVRLARAKASIQVMQRVWRGHVGRCVFHARLCDVRARLIQRVYRGHVGRRIFHEHLCQKRALQIQCAWRVHKACKTLMQLRNIFEQEQARLRAIKREEERLRRIAEAEEARRLKEQKEREERARRKQAAISMQRIARGILARRVFAMMKEQARREQEAAVCLQSGARGLLARRHFAMLKEQQRREQNAAICIQSIARVLLARRELAMLKDHERQKHKAAVYLQSFARGMLARREYAMLKGDQKREQAAIYLQSFARGLFARREFAMLKEEQQREREFHAAICLQTIVRGLLARRRLAQLKDQKQRECEAAVYLQSFARGLIARREYAMLKNDQRRERELQAAVCLQSVARGMLGRRYFATLKDQQRQECEAAINLQRVARGMFGRRQYNELKEQKRQEQEYSAAVCLQGLARCVLARRELAVLKGQKNEFNAASRLQSIVRGAMARRRYVTLRKNALAIIMKREAEQAAKLKAVTEENDRLKQQLQELLEANIELETLVSEWKCEQEVIKASSLVQETELKRQINTQKQKLSSVQQEYGTLCSYLDQNGMGDANHNNSSHYSERDTVDSDSDRSSVSSGGGPYDSPFQEDRLSRDVSGMIESFSSSRGPTTKSKLRAGVTQMSVGKWMNGPRSSKSARTPTPTNSSKSPNMSIVEDPTVTESARRRMFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF98</accession>
    <name>A0A8K1CF98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0489 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF98"/>
    <dbReference type="OrthoDB" id="418142at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024131">
        <property type="entry name" value="UPF0489"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13225">
        <property type="entry name" value="MISEXPRESSION SUPPRESSOR OF RAS 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13225:SF3">
        <property type="entry name" value="UPF0489 PROTEIN C5ORF22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12640">
        <property type="entry name" value="UPF0489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="386" mass="44285" checksum="A5E9BB08C7B3B2C8" modified="2022-08-03" version="1">MAHREQAAAVTPLRVVITDDHHHVLPEIHLAIRQRRLPFTGLHIVHFDAHPDLSFSKSIDPSMIYDPEQLYDLLDESESGIAEFLLPLLYAGHVNRLTWIKSPWAEQMRVGSMERVAIGQHQLSKRLAVSCPWLHFVEDGLYASESELEPATFKHWDFSVCELSRDSGDSFVRAGEPWILDVDLDYFSTWNPFRKVLEKYCSPEEMELLVAVFTSSRFKDIDLPLDISQRQHEHRAFADAMQRIRDERLFEKPEAEETRAIIASLRALFDQALRPDELLSRFLLLIASKNDEARDKIWSAGPSLDLPHHESSSTELQRLLEDFDGFVRREVSRVGPPKLVTIAKSAADQFTPPHHVEIILSAVLKTIEIVCGAVEIERIEYEPIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFP6</accession>
    <name>A0A8K1CFP6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFP6"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010708">
        <property type="entry name" value="5'(3')-deoxyribonucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052419">
        <property type="entry name" value="5_3-deoxyribonucleotidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35134">
        <property type="entry name" value="NUCLEOTIDASE YQFW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35134:SF2">
        <property type="entry name" value="NUCLEOTIDASE YQFW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06941">
        <property type="entry name" value="NT5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="313" mass="34790" checksum="BAD5F7169A8FFC5E" modified="2022-08-03" version="1">MTEHRVALAIDLDHTLGQLLPAVVDWHNASAKTAVKEEQLKTADWIKHLGIADADVEEKLLEFYHSEQFTSNVATVDGAKDVLKPLRKYFSLFVVTDRPRVVEKATREWLDTNFSGVFDKLLFLDEDSKDDIVSRKKEIYDEFKVKIAIGSDPAILVKTTEDIDHSIKVGTVPWAAKEGTGKAVVVSDWAAAKPVLEKIIQDLGLKPSDKVSNGPKLSRYTDDLVTVSTKKPASFYASMINSKFVVQKQEVIRLQAAEGAITTAVQAAEMLKLQKHAAVTKISTRYVFKKMRGEPGHRVPKIEIILHKTAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFR2</accession>
    <name>A0A8K1CFR2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009448</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFR2"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479774" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="364"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="510"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="403"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="659" mass="72056" checksum="5805ABE036F9531B" modified="2022-08-03" version="1">MKFVFTLLLGAFALMGTTISSTEAQSCGPRVRKNWDAMTQQEKTTYRGALQAAMDSGAFIKFVEMHTEMRSEMEAHGQCMFIYWHRLFLVIFENMLRGQGEQYACVTLPYWDWITAHSRMTNGQCNSMLTCSSVLAELGGVPTTSRQRQVSINGEATQGYCVSASPLDHFCESGSVQGNRCVKCVPRGDWSRITLPGTCSYASVMNQIFSAKSIGEMSPNLELGAHNNVHANLDGTMGTFASPADPVFWSHHSMVDLLHTVFHKCRVGETRLTFEQKASHPVAWTSCNRRDGVPFNPVDSITMRTGVNGRNPIQGSQDPLIGRFFQGVPSRFADLMDIRDLGDSSYTYELSGVTATMYTQCDGTPSPTPAPVTTAPATRTPAPVTTAPPTRTPAPVTTPPTPVTTIPVPTRAPVTPAPVTTRPAVTPRPTTPTSTQAPAPPTQTNCPWWSLWCRVVSHINNRVNGGRWGRTLRETAELEAAGASFFGVDGNVAASDFTASINDAAQISLPSGEVNTNTGDASDAQQQTTNDPSQTDNTLPVSIVECEPEPGTQKVHDWYNELTDLIGGPSLKSFDEIERMLCVYQDECLGGVQDYSEEFKKIWNVDHPRCKTIVDEFNAGSQTFCVEDWRERTIQHLGCPLNTTAPASSDYNPAAQRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFX3</accession>
    <name>A0A8K1CFX3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFX3"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455826" evidence="2">
        <location>
            <begin position="18"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="160" mass="16671" checksum="6E9CF56FDB6166C4" modified="2022-08-03" version="1">MKYTALLCAAVATFAAAASQDPAIDNPSNNKDIISPTEALDVIKEANLPAGMKLTGTVDSIQPPANTNASKEKTSTDIDTHIEDSGSVESKQEWLGYGGRGWGGWGGWGGWGGFGPYRFGWSCGGLGGWAYPLGYWNTFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGB9</accession>
    <name>A0A8K1CGB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_005111</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGB9"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="5 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 9" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="118"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="299"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="450" mass="48679" checksum="65428921AB1A3A36" modified="2022-08-03" version="1">MHTSQALATLRRSRTANSNEPLDGGFRSLSGDNHALRRSFPTERQPLIPPKRILSCENGRQSSSSFSPDVSNKRSVSKPTWKEDANAIFHFLVHQKLNVMLLTAPFALWASLAHWGDTWIFLLNFVVLIPLANMLGEATESLAFHTGETIGGLVNATFGNAVEVVVAVLALSKGEINVVQSSLIGSVLSNLLLVLGCSFIAGGFAKKENSFNAVGASANSTLLILASFAMLLPSYIFYFSGSDSEESRVEKTLALSRVAAIFLLFMYMQLLYFQLFTHLHLFQGEGGEDEEVDLSKRASLIVLLSSTLLVALFSEYLVGSIDGFASELNVSKSFIGIVLLPIVGNAVEHVTAIKVALHDKMELAMGVAVGSATQVSLFVVPVVVIAGWIMGRPMSLAFPQFEIMVYLMAIIIVYAIIADGKSNWLEGSMLLTAYALVALALVWVDIPATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGP1</accession>
    <name>A0A8K1CGP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable methyltransferase BMT2 homolog</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009883</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Probable S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BMT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGP1"/>
    <dbReference type="OrthoDB" id="5954793at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000656">
        <property type="entry name" value="25S rRNA (adenine(2142)-N(1))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03044">
        <property type="entry name" value="BMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021867">
        <property type="entry name" value="Bmt2/SAMTOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008:SF1">
        <property type="entry name" value="25S RRNA (ADENINE(2142)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11968">
        <property type="entry name" value="Bmt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="276" mass="31419" checksum="4714924174F8C32F" modified="2022-08-03" version="1">MGAMTPASASTAASNAKNKKKKVARKAIHIAAPKLKSRRKARQITTEFHRLTHELDQLKKDTEMDKSEKQQRMNEINASLDAMGGRSAYQDASFHKTSKWVFQLLTQFDRRPKSKEPPLRTLEVGAINTQLLSCPWLNVRAIDLNSKHEKIEQCDFFSLKPSGEYQVIVSSMVINCVPDAPSRGRMLQLYYEHLQPSGLLFLMLPLLCLRNSKFMTIKRFREILEAVGFHIKETKDSPKVSFFCLEKLPDKQPSGKKFPQQMLVPGAKRNAFSVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHV8</accession>
    <name>A0A8K1CHV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002290</name>
        <name evidence="12" type="ORF">Poli38472_006317</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHV8"/>
    <dbReference type="SMR" id="A0A8K1CHV8"/>
    <dbReference type="OrthoDB" id="186195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="136" mass="15340" checksum="ED085C55D3CB5FB0" modified="2022-08-03" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQGSAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ79</accession>
    <name>A0A8K1CJ79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ79"/>
    <dbReference type="OrthoDB" id="122038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="19544" checksum="A865CD8BD84A111D" modified="2022-08-03" version="1">MSVLQASRRRQLTALEQEESRSAFELSTHGNVEMTAKQLRRCLNAMGLATTKEEARAMVYELDYNDTETITLTDFQRIYAFKTAHRTDQDRFNDAIRMLDPSGRGKLDLLGLTRGKEMDLATLHRHIRVYCKDEDTIHDCLEEEDDLSSSVVHCETLAGFLGLEQATNEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJA8</accession>
    <name>A0A8K1CJA8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJA8"/>
    <dbReference type="OrthoDB" id="105698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="70"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="31499" checksum="46FA601B915576CE" modified="2022-08-03" version="1">MLSEPNKWSFLVRQAKNEDQVSLLGLGGHLVTNEDGIWGFSWLPKLLTSSTFLDNGIQGVHTVQTVKKEIVGGRVIEKMDKYTEFIVGLRISEKATSNCTGSLIASRFVLTAAGCWRPLYQFKWAVFNTVATSGKPSEVIAIKQLTRYDSFRAGILGNNVMLIELENASSRRPIAYVSKNDATKMPATITAFDYGAYRKLFVGHWSTILRYKKFKVYNNSDCPADVQRRLDKITVCALDGLCYGDFGSPMVLDAGTDKQKLFAVSGMRSTVLPPVCRSQPSGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJE9</accession>
    <name>A0A8K1CJE9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJE9"/>
    <dbReference type="OrthoDB" id="186871at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580:SF28">
        <property type="entry name" value="BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="40145" checksum="0762ABBD6ECEB305" modified="2022-08-03" version="1">MTGLLDVEPTSRVNYRQVGTRTGGAVIRGAVVRRQPPPDPSTRVASIPSKYETLLHRDPNERDAFGNRTQRFHASENDQPGPGSYYKPPSMVRTTTDSGSVSRLGYSTGFVSKSKRFSDRVRDVAPGPGQYQDTRVDRKFQNKKHGTSCFASTARSSNNDPFLSPSVTVPGPGEYNVSHTSSAIARNIARSAFTSKTARGFAPKLDVPAPGQYENPIELAQSIRGGNHSPQSVFKSTAKRLDSPIESLWTPGPGAYNAEDAETALRYDWIARAHTSAVFQKGNADRFGRVPTKRATEADVGPGSYNPGSPVSQEAGKPSQALASSTFRSSTSRGTLPGGQTQPRDVPGPAFYHPSSPDKRSHILNSNKKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJK3</accession>
    <name>A0A8K1CJK3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar ATP synthase subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJK3"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000026">
        <property type="entry name" value="V-type h-atpase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30225" checksum="46B83D12FAE13C3B" modified="2022-08-03" version="1">MSAIQVAPTRMALTTFKGKRVAAKKGFELLKKKADALKMRFQAMLREIQKTKMAMATEASDAFFSLTQAQYAAGDFRTKVIESVTTAEIRLMNRIDNVAGVKLPVFTEVEVTREKTENIGLAGGGGKIQNCREKFRVLVRALIKLASLQTSFVTLDEALKVTNRRVNALDNVTIPRIEKTIDYIMRELDELEREDFVRIKKVQANKIVEEKKALAIRKAAAEAAEAAEANDVPSSPKPSATPAFDPNDPFADISADRDILAQYEPAADSDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK51</accession>
    <name>A0A8K1CK51_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK51"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="756" mass="84971" checksum="D00BD751BB4ADCD5" modified="2022-08-03" version="1">MAKKRRCCRFSFVKLILVALNLASTALTLMSGLRENPALVFLTGRYDPIRQRLREGTINNEIADHDIYRLSGLTSYQEVGDNFRFISLPRRDPASVGQKRSVCMNINSVNASIMGIMYDDFWGKGPRRIQIYVFSISAVNCKVLNVKPAWVQTCIKSNGNTTTGCHNYILSNFEQLQRNRSVIVGSMNDFGTSGTPFLKCYGRPKQDFDFQADLVTHQTFWAGGEYHLQIQTSDCKAKPLLPNPNWDWSLFQVEGVDDGSDVVLAIPPPGWFTSVITLLYSIASVVLILLGIVSALLQTRAVRYIPDELRYSNDQKIARYLTPFMPISALLTDDVRSIITFKGSLLIASDVWMNHWLYIILSMLDVVTNLRYTYAWFQIGTWYLLMKVTVENFIFLTSVLTKMAWLMCLVHTVIRFFLKVAIHTLRSMQIIRTTTRDKLQGYIDGSSMFLSFKIYNIMLCIILLLIIQVRGTATLMVRSVPSKIGTYGGIPKIPRIWGSEMMCDFATIFLILAACGQVIGAVFMLTRFRLVTENRVMRLLQKRYVVVGWDGLMTASMLGLDPTTSDIMATGRPRTNCSLGTLLQLLYLSGPSAFVRLAGDYIFSGYGFSSAPLEFHFPVKRAVSMGLLDRAKGSTYRSKDGASNATDIDNIVNRSAVKPASISMSTRQVREEAETTPRSEDDIAPLPKRSIFQRELKIVTDGYFGKMYIIDEADAGTVITNKETGMREYVVTDALATISIVDIKWVLGNKKGLFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKN8</accession>
    <name>A0A8K1CKN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_011608</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="707"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1546"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1584"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1622"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1683"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1827"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1856"/>
            <end position="1879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1899"/>
            <end position="1918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1924"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1961"/>
            <end position="1982"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="12">
        <location>
            <begin position="234"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="816"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2026" mass="232717" checksum="C9ED0362C5FA8B00" modified="2022-08-03" version="1">MSMSGMMTEALEMQRQMCDEAMNLVKQGTAMQNAQPPNVAGAEASLTRAVDIMEQALSIRYNSAEEKDAAERLNNKMLRYVKMIKSQRAKNQGGGAAGKRQMQKHNILELENLPEIYAPVMHLLHNSQALGDIFESLKQTFGFQESNALNQKEHLLLLLTNFKEQADSFDDGKKKKKKNKKMTGEEALEDYMRQRDPQQEMDLANKGIKRFHTRLFANYVKWCKYVSKKPAFTSDPLVDVSLFFLIWGEAGNFRQTPELLCFLLHSMLPQATSRDNKESGWFLANVIRPMYVELKRDNDKKTSKGERAPHAEIRNYDDFNEFFWSKKCLKYDIKTIGEAFANVDKKGRPKIVKKTYKEKRTWIRAVMTFRRIFFFNCALFLATLGFAMNMVLFCPDSPIMYGQDIQPLSETNVFEILGKKYAQPADTERVQTEIMEEEEGKPKCLPAKLATCLGVGNYNDGETFAYLPIDFRTLLVEVPFTNCLEKTSGRCACYHKLIDTCWSQADTAEEINEDPAEGEPSVTKITYDQSGCYPDYKEAMLKILDEDEGGYLNCGKCRIDINSLIKKPTRVVDLIMGLIDFGGRKDKGVMAMAGGVGALGLVIVGELVNRFSSGFSMGFVGRSLPVPMKVWCRYTCFWIVLLIIKLTFDYQFMMKALVEASLFIWNANEKDYLQYSAFMVQFSFHNIAYLFFLWIPAWMVFLYDAQIFYSILSVVVGSFAGFNMRIGELRSFRILRLTFKSIPGVFNKKIVPNIYEDLDQKKKKKANKKKKNVKEDVPMPERRFERISMSQGNKPLTVKAQKYSSLLEQRDDDVYNELRTPNGNDDDVSSQTSRSSNLGSITGVSGAEFERTIPFAMAWNRCLSSLREADVISDRELNVLSYLIDSKDTVGRKLYPPAFLTAGKLDESIDIVLECHALYDKLKTDKKKKDKTLQKIEVTMRERLLKDDLRIESILGSYKFSSQVLRILLGEEHKELDECYNFIEEMASHQQILKGLNLSNLYQCRAACAELMKAILEVPKKSTESSIKFQRSLYKVIDTVEAVVTCLKKVLGKQENLVQLLNDTPLKPNSFFFPADTQHYASLQLQKIVNDEAALDIVSRAYQLLTVDNFDAEPRSDEGRRRLRFFANSLFMDMPEAKPIRKIRSLTVSTPYYNEIVMYSVKDLTSQNDDSIKLLYYLQTIYPFEWENLLERLQVKDMNEALKKNPEEVQLWASYRGQTLARTTRGMMYNEDAIRFLHWLEIGENEPMHQAGCQCNKCVRLNEMVALKFNYVCTCQIYGRQKDEQRQQAQDIDFLLKKHPSLRVAYVDGPKKVKDGPPKFFSVLIRAMEDKIVEVYRVELPGDPIVGEGKPENQNHAVIFSRGELLQCIDMNQDGYLEEYLKMPNLLSTMDRHTDKAPLTIIGFREHVFTGGVSNLASFMSIQELNFVSLGQRMLAINHVRQHYGHPDIFDKLFAMSTGGTAKASKGVNLSEDIFAGFNSTLRGGYVSHEEFIQVGKGRDVGMQQLAQFEAKLSSGAGECVISRDALRMATRLDFFRLQSWFYGNLGWYFTQTLTVFGVYFFIYGKVYMALSGLDEYFLSRGGLGIGGVLNTSWAIQFGFLLVVPVVAVVGVEQGFRHGLTYLLWNVLTLGPIFFTFQMGTRMNYFDRTLLHGGAKYRATGRGFTIKHEKFAELFRFYAFSHFYRGVELLFLLLVFAFYGTFSWCNCSWRMESQFYSNIQPTELEWKKRCYANHYQTCVLPTNQNYGIMSFSLWIISATWMWAPFFFNPSGLDWDKIIEDYNDWQNWLRTTNDSAESWFGWWSNELAYIEHSSWGSRMVSLIRKSRFLAVAIGMYLQLVYNVYFERRDEAIKSDDKMLTFIFAGAIVVLMLLLVCCGYIASRVTKKMTMKQRKLRKMKFIISCICMAIALLSLTVLAITNVFEVIVIILMAAYWFMHLCILRGQSHHIAVRAMARAYDRAVGWIVFGPVMFVAMFLPFIGLFQQRVMFNNAFTSGLEVSKLFAHDVAPAQVVKVKRVSKKKKQRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLF5</accession>
    <name>A0A8K1CLF5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLF5"/>
    <dbReference type="OrthoDB" id="160454at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="571" mass="64789" checksum="2F1ECA820B265BB8" modified="2022-08-03" version="1">MIRRLSSTVLSSLEFRTQSILSRLPSPFARFCYRLWHGVTKIYHAVDLRNEYHGGVYLTRVVIQMVAHTYCAYEASTVVSEHWMNDLRVALMVANSWVVPCLQLLFRKYAPQGRLLSITLNLTLDIVSIYVIPIVIMLPTTREFDTTLTNFPEDKWYTDKWFAVVVFQFRFIGVASITEFLARIFITYNVARNLRFISLMLRKEEREQTNEESTAKMAIAVAAAIHPAPAPPARRSLSSSTASLLSESKEKLKQQIRRRCLRLELVHSAILIALGAVVLRVHIKASELEDRVVCSTPVFPWFAVQPSCLFLEFNCEKLGLVGAEDELDEFLEQFDERHLGYLSIRHCPFVQMPPRITQLTNLVGLKLYKSAVHSWNADAALTSTDHPNLRLLILADVHVTEFPEGLLSTDFPQELLDIEFIRCNLTDLPSNLDERWPKRAVLVFEHMPFQTFPLALTRLQPASISLAMSNIDTVPAEMMDNMFLYYIVLNGNPIKTLPSPVSLGTRMYWLSIISTELSSLPAHYSQLISIDAGNTPYCTALLASSVTPKNVDCASSPPSQLTMFPKEELNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLG6</accession>
    <name>A0A8K1CLG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Early endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLG6"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901981">
        <property type="term" value="F:phosphatidylinositol phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039937">
        <property type="entry name" value="SNX20/SNX21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20939:SF11">
        <property type="entry name" value="LD12265P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20939">
        <property type="entry name" value="SORTING NEXIN 20, 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="462"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="577"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="68256" checksum="5A94CBFB3F0D1362" modified="2022-08-03" version="1">MYSSYYTPKDAGRQSTVLTDHEALRRDENTHKKLQSDETKLRPIDLETIMSSKAAVKYWYLHRPKTMEYVHKNATKIQSVGRAFAVRQLKKKYGMEYVVALAKADAQKKEAEKLAELSAEEREAAEAANLAYDARVQESRRLRMEQIERERLAEEELRQRLADEKRQRLVLEEERKRKESEEKAAAAALAAAALAAEEEARKKARAEEAARQAEIAKAQAEAAAIKKAEEEEAARLAAIKAAEEEAEAARLAAIQKAEEEEAARLAAIQKGEEEEAARMAAEMEALRIAEEKRRQKAEEKARQEREEAERAHAAAAAAARARVEAEQSEKYEQSLSKDVPVIVRKHGPGRVIAYNKEKETYTVKMEAAMGGLTIDVKSSDVNLDDDRILSPRTKVDTPFGAGEIVGLDPHVGCYAINTEINAPEGEQFLAFVQIGDVTVHVEEPEERAIVENASMPIPDEIGLVAARIVDSRVVNRTGKKFIQYKLEIRTNNYGTVYCWKRYSTFRSLCERLQKEAGYSRKEIPELPKRQITGNFSQHTIGERAEKLNVFLAAAVHAEHLQWGIRVDDQIAVYKRRVKRPASQQQQQTASRETKSRGFFSSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLL8</accession>
    <name>A0A8K1CLL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitric oxide synthase-interacting protein zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NOSIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLL8"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023577">
        <property type="entry name" value="ENOS_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitric oxide synthase-interacting protein zinc-finger" evidence="6">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR023577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="32362" checksum="523E70E9E94D8132" modified="2022-08-03" version="1">MSRHSKNATATTHFTYHERQAAGHGTLKRRFGKDSQLAFGFCALCLARTEDKQPLVSPSGYVYCKECIYANLLAQKRAIQENLDAYERFCEKREQDAQDTLVAKEREEIKKFLSASDGSGVNGQNTKSDDAEAIQNKLREKVDRTTDDAKRDAMKRTSFWIPDCTPTAQNKMDQPDTKTRDPMSNEELKLKHLMPVKFEWLAEGSSKDKHVVCAVTKKAITHQLAVLLRPSGQVILDSCVKDMVLPTMTCPVSGLKLRKKDLVKLQTGGSSFSAHSNVEAKKYRPTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM54</accession>
    <name>A0A8K1CM54_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM54"/>
    <dbReference type="OrthoDB" id="74529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035446764" evidence="1">
        <location>
            <begin position="17"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="613" mass="68850" checksum="B8B798536DE72A9A" modified="2022-08-03" version="1">MLWLALATTPLTAVDCVTREYPHVAALDHVVAHIDAFLDRSAAYSLLQAAAIGNAKLFDRVVERIKPPTTNVFLYQNWLVKAMMLAVEQGHKEIVYRIHHHHPGRLASKAMAKAATRGDFDLVRWFHENRREDVWSPETADCAAAIGRLDMVQWILEHRVECFGLEGFMRAVENGHLPVVQWLHAQDLVRHTQFLGDRAAANGHFDVVRWLHEHDIDQAFSSSAMDAAAARGHLPMVQFLQENRTEGCTSHAWNSAILNGHDEVVAYLRAHRDEDISDDLVTEAGRAGRLDLIQEYEQQFAEDPDVLVVALSNAAAQGHLEIVQWIVQERDGFCSWNGLRRAALHGHFHILKWVHENRCGQWSTNVMDAAAEGGHFEIVKWLHENRQEGCSVHAMDSAAGAGNLELIKWLNENREEGCTMTAMDAAARKGHLAVVEWLHENRPEGCTTDAMDLAADAGLLEIVQWLHVHRDEGCSVQAMDLAADHGHLEIVKWLHENRREGCTRGAMDDAPLEVARWLHMNRREGCSLRAQLMAGGMGDLAKLQFLHLERGDDISPLVVSVSARRGHLHVIQWFHSIGIDVSEALGTARYLGYPHIVQWFESLEPTEAASVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMC4</accession>
    <name>A0A8K1CMC4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMC4"/>
    <dbReference type="OrthoDB" id="514167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019265">
        <property type="entry name" value="RTRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15924">
        <property type="entry name" value="CLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10036">
        <property type="entry name" value="RLL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="255" mass="28859" checksum="BD6A3F3DBA8F13DC" modified="2022-08-03" version="1">MAPSTEAQEQQRVQLQHKLTQRLALLGCSVLDAVGETDGSPLTSRQCAQIIMWLEDRVIRHDSIDARSGMREALSPQKWLLISSEYLERQGCPLKTPEKEMADSGAWGSFIGLDMYRVLLWLASHTISLEYEEHADRIKADLRAKEHTEAQQPSRIHPVDNIACSEELWTAFQEMQKASHGADTLRDHVQVEDKGDECDNDPERKADMENAVMKLRQAYIDDMKALQLDINRLIARAQEYTANPKTDASLGRTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMV0</accession>
    <name>A0A8K1CMV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMV0"/>
    <dbReference type="OrthoDB" id="58806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="281" mass="32304" checksum="53BCD9F39BF432F4" modified="2022-08-03" version="1">MSEQTIVSPTSVGVAVDCGVATEAELAWMRRCLPIFVQPKVDITNGNQLVKVFFRFEREESSARLDCKLCIVFAGESSYNRVYEHSENFVATLFYRTFNRRTYKRTADINYMEFHNVDLSPDSAMPWESIFSCDYGGEQKWAQGEKANICCWFSLMHHYRVDVPYEEWKRDGARPFVYLNTCNHMIGEHDNNPQMAKYDWTEYAFQEGDADDAFLYVVDHVPTKCNLYSYVCFWKAHNGGGCCDRHHTNSVSRSGKSIYVKAPETSKQALTEPISDTAAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNM6</accession>
    <name>A0A8K1CNM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Repressor of RNA polymerase III transcription</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNM6"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037240">
        <property type="entry name" value="RNA_polIII_Trep_MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="234" mass="26779" checksum="AA70EB259AC416E2" modified="2022-08-03" version="1">MKYLEENQLTWLNSVLSSYVIGDRVLTGKIEAYSCKKAGADKKLAKSLDMYYQQEIEALSSDLLSSSPLGPLTSSTTRKLLINLITTMNATFPDYDFSTVKPEQFCKEADYRIAVQRINHDLAEVFDLESNGFVEKMWESIAESIKPDECEVYSYIPDMDSDPFSDGNLSSFNYFFYNKNMKKILYFTCMSQALTTYEEGMDDEMMEDAEAMDDDDNDVIEDYFGMSPDWEDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ44</accession>
    <name>A0A8K1CQ44_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014573</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ44"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="80" mass="9000" checksum="AA27018395ECB098" modified="2022-08-03" version="1">MSTTPVNNMKYRFLGNTGLLVSRFSYGCFMMTERALSFEQAYAVMERAYQHGVNFFDNADMYAGGHSEEILGQVVKAGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY1</accession>
    <name>A0A8K1CQY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007646</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY1"/>
    <dbReference type="OrthoDB" id="340227at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF157">
        <property type="entry name" value="LA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="6">
        <location>
            <begin position="128"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="240" mass="26596" checksum="865C39376FED5A2C" modified="2022-08-03" version="1">MGVNANDAASATSAVTSEGGVKYRLVEAEEVDATKLVTSQPPSAAGTRAPKTKAKGKTSWSQFPLDDAPATEQTSSEEGSQDRQRNFRGRGRGGRFGGNGGRGRGGFNGRRPVYDDNGVYYNGVFVPNTDLKVTAQWAKSQIEFYFSPDNLVRDMFLRQHMDVDGYVPLAFVGSFQAVYSVHQDYESLFDAVKESTILELDEENEKIRLRDNWASWLWPNGDGTYGVPRYIKLQEEESAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR39</accession>
    <name>A0A8K1CR39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR39"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF9">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035438940" description="Beta-lactamase-related domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="44"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="300" mass="33146" checksum="9EEAEF5E40851DC7" modified="2022-08-03" version="1">MRGISPVAFGFSLLLSSAKAGNESLTDTYNKYRDTYCFSNVTQVTENGTTVFRVSDGLANEEFDVAMQPDCLFPIGSNSKLFTSVALYQLEEAGRVNLSDPVNNWLKQDDFVQFGYPNQTKWCPRLANSTDDSPCEEITFVQLLHMSSGIGDSVNCDNVDSEHCYRSAEDLAYYKGSIGVYVGRFINDPLVFKPGTNYSYANPNFVLLSYLVEKISGQSFGGYLKEHIFDKLDLKDTIYDPYAGALSVNHRVTDEYLSYFIQGEGGQKPRLVLTGTCSPLIKSGALSGTGGLKGTVEVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR45</accession>
    <name>A0A8K1CR45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_007736</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR45"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="125"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW68064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="643" mass="69779" checksum="2A14C5B1F97060D0" modified="2022-08-03" version="1">MLPMRQSFSGRSSSSPVVARALSAPRSMSLHAPGVRRRSSTPLSTVLEINDDDEAEEGAKLFNGQPPAPPQRKPTTVLLPPEMRRSSTLSALSPGQSRRRSSNRSGAHGKKDLTPQIGSFFMYASVILTVMLGPQIGWQTSQLNLARFHKVEDCAENPVKPGHCIIFPGHTSVQWIMAVMGWVLGAAAGSLGSSIPAERFGRRWVIIMNAMFLVAGGTLQMLAPNIYLFALGRFFNGIASGAGSTISSVYLTEIAPPHLRAGFVVAFQATGSMGLVAVNIVHFTISGSPNSWRWMMAFPAALGAIQLLFAPFVLVESPKWLLANRRKLEAAAAFQKLYKSGSFEELELAVKLETERSVRRQILQAQESANSQAKASFWRDAWSKRCSKQFTISCILCIGRQFGGVSAVFYYSSGIFADAGIKDGRVGNLILAIVNVLAVGVVCIFMKKLPRRIALLGGIGGMIFCSIGMTMALLNKSSAAVPLTAAYVGFNSLSLSPLPFLVAAEVLPEQIKTTGISFTTFINWVCNLIVGICFPVLAEHTGDLTFVPFTGMLVCFWLSVFVMLPETKDKTVEQIQLDFRNQVGFFDKFKKIKSVDVVDEKKEGEIVPTDAASAATIAAEARRTSVEYAMSTQPPRPNFSRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS62</accession>
    <name>A0A8K1CS62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS62"/>
    <dbReference type="OrthoDB" id="187808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052603">
        <property type="entry name" value="EFCB6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20875">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20875:SF0">
        <property type="entry name" value="GH12158P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="631"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="953" mass="108124" checksum="0000E9673D2A5BC7" modified="2022-08-03" version="1">MHSSHEFRSLKAKIRVLCKQRRIRLEEFMKTFDIHHVKKIKVEQFKRALDVSGLQLTSEEMNLIVAKYRLKDEPLFVDYRRFCDLIDKAFTVKGLEGKPDLCLSIHNELPAQKKFAIVPLSDMEEQVLTQAKAKLATAVRNKGIVLKDVFHGFDRSNAGKVTKSQFVRDLLDIVVLSSAEVEALVKAYGNELDVNYRVLHYDIAPNSGNISPGRNSPDRPRRFTAPASMSSELDAVQELEASLSELTMRDRIRTKNFFTDFDPLRTGKCTEAQFKRCVKLCYSSVTEAELDLLVKKYLIRDLVANKVDYIRFCNHVEGKSNRFSSQDINSDDTLASFAGLTPAADLKCSREVRGNLSDAEVATFQAMMQRLSSYCSQRRLLLKPAFQDFDRGRREHITVDQFFRVMTMLKLTIASEAERKALLKHFSSSHGDRFVNYVTFCYDIDHWEENNNRPSSSGGRSSGIASEILSPTRIQSDTFETTAASTQVRSVPMLMRYIKQTVKRDRIRLEEYYRDFDKLRHGKITAAQFAAGLGAGGLLLTKEEVGLLGEDYALEDVDSIGNHLVAWKKFVEDVESVFTVKGLERMPNHDLTDLQTKGEQFGGAKQDKDLTSMEEHKVTQAIVTMKKAIDRQRLEFKAAFEDFDRSKQGFISATKFDRVLSMFQLLPEAVTARLIVIKFREQTSMGNSMTLSSICDVNYRAFLNALDLVGKVLANGDDTTSLILPGSVAYRQGVYASGLMQHDGMRRQTRGDKAGVADVHQVVRELRRQLDAKRIRMKEFIAEGDKLRSGEVTVAKFHTALNRSGCVLDAVDVNTVTEHFRSAKNSDKIDWRAFLEALDRSNDAYEGCSPEQVEVSSVDVPNTKVSGILTKLRSEVNSRRLHMKPYFQDYDHNRVCRVTKFQFAAVLDMMKLNLTPQEIALLQQQFVVHATGRKTTTDVNYVTFIQAVDSEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU05</accession>
    <name>A0A8K1CU05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU05"/>
    <dbReference type="OrthoDB" id="20835at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013885">
        <property type="entry name" value="DUF1764_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066:SF1">
        <property type="entry name" value="DUF1764 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066">
        <property type="entry name" value="GROWTH FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08576">
        <property type="entry name" value="DUF1764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="215" mass="24119" checksum="B43BB2F2EEE324AC" modified="2022-08-03" version="1">MGRKRRRGDAKETQDAAAAPTKQESPVNGTSMTPGNGKKQTKTLQLKIIGVKKPIETKKVEAPKEAAKHHTPEADGAAMKKKKKSKKKKSSNDDDEAISPTEKQSSKTKVDTTDIDDLFQSLKGKKQAQIEAEEKQKQEEEMARKREKKERLRMEEQIKKLEAQNTNSTAVQGKNPEARPVRYDEDGLPIYTEESLQINKGGDTAECPFDCWCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVD1</accession>
    <name>A0A8K1CVD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Voltage-dependent anion-selective channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001536</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVD1"/>
    <dbReference type="OrthoDB" id="7827681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000012">
        <property type="entry name" value="Voltage-dependent anion-selective channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="33154" checksum="DBD208F6B169AD13" modified="2022-08-03" version="1">MGGSLQVCGRAAPDTLVFVILEASDRQASMVAVLYKDLAKKAEDVLKDDYDFSRKLKIKSKASNGVSFTTEGQLNTNKSILAKVSGGFTHGQSGVVFKKLQVTTQGRLITEAELPNVLTKGLNLTFKLEDGSVAKHASAKQVGVVGAEFKQDKFSFNADADFVGNSVKAAGVFVQDNFVVGGQVAFNVEKSALTEHNVGVSYAASDFATSVVTKKNFSALSASFHHQLSKDTVYAAVLDYDLKSAANTLTVGGRFKADSETTYAGKIDSEGFVSLASIQKIRPYVALTTSVHVDAKNFEGDAHKFGIGLTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDD4</accession>
    <name>A0A8K1FDD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDD4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="207" mass="22455" checksum="98E6B22B2E6DBD47" modified="2022-08-03" version="1">MHKLFSGGWVGPAEVGGSLFVLLFSMNYYRSFLQWNAMRSDVKTATLSDPVLQLLTPMDCSIVMSAVVYGMLVAGSVYCRNKPDVFITAAQTLTLALWTRMLMIYLVPVKSPRGAIPLSSSIHETVGSAPSLVACTLLAVTRRHHCAWRWAFASFAMVSGLLGLAQKLQYTADLITTPSLVTLVASVVAAVRQTVGQITSKAKLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDM3</accession>
    <name>A0A8K1FDM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Poli38472_011671</name>
        <name evidence="21" type="ORF">Poli38472_013780</name>
    </gene>
    <organism evidence="21 23">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDM3"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036433889" description="glucan endo-1,3-beta-D-glucosidase" evidence="20">
        <location>
            <begin position="25"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW55018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="TMW64791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="33914" checksum="264772E641702238" modified="2022-08-03" version="1">MKTFLLALVLAIATLCISVNVVEAKGVCYDPIHGSAKVTRNSINADLRRLREAGFRSVRVYTATLVNENLGKRIIDNKMNAAITVPFVNDRPGDSESHIKAAIEAAKYRVGNNRVTHIYVGNENLASVNAVPQKMFDYIARIKAAVPSDVRVGTVQRNTEYLDPARNGMSRLKELLSKCTIVGVNIHPVFTPNTPANKAINVVNAQWNQLMGNVSNRFPGLSGKIAITEVGWPSGGSLNGNTGSKSGALTFMKAYAKWRRNNIIEGRSFFFQAFDQPQRTDGPFEKFFGVFNSDRSKKYSSFNFNDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDS9</accession>
    <name>A0A8K1FDS9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDS9"/>
    <dbReference type="OrthoDB" id="125510at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="186" mass="20596" checksum="2F7CD046F44AB536" modified="2022-08-03" version="1">MEMTTEEATNMLKRTHSEAMEGVDEEESDAETTIDDGDGPLSPCLWDGIEVFVEATQASPPKPSHTPELTLSPESQLNVLSQISQLAELRAKEAQQTATVVSQMQPRPPHVWASAQVSNRETNEKTKKQKLSTGLPKLTSTKRGNISARLVADMADWESCDETVFAVIDEDDMQSWQWADLSDSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDY2</accession>
    <name>A0A8K1FDY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4866634at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF33">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF3638" evidence="8">
        <location>
            <begin position="1343"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="9">
        <location>
            <begin position="1701"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2427" mass="275265" checksum="E833FF74B9CBEDB1" modified="2022-08-03" version="1">MLETVVEETIGLGERDYNVEMMLSMCNEWRDALDQAAEEYAATIASTYQIPQQAFLEALRQSKQYPQVDEPRVVDLSALAVPSTDVRRRALEQVKVYEFMDPSSDSAQSLLEFLHTIPSEGSVFKTVTGLRNIEQFMYQQSGRLYRVTMEAARANIASQIALKWNAIEGRKLQARQLEAQIEDSLAEVRKYERLLDDEVTRLRSEYSGRRYRRKPSSPQTRSYEGSIRAWNDDVESKRNELIRVENMPEYVISPLPVSDADALELLFFLNMPNDLGLLAHLSCTAQLAMGKGESIHVQLSCSTSWMSHFNQHARLVSSAVPQYVTAFPKRLDVPSSYGPKNINDVWSLGDFRSRCLWFPDASIELAWFGPLRIYVNPFLITHEDSICWLTAQATDWDWANAYPGGNTRGNTVYAKADEISLGSEDFAEYVGVTSLRAYPVLQLRKLFTAMESDTIQWQRDVMGILSRQAVYQVGVLTDEAVPRFQWHFDLLSSITCAEFCAALAKQVARVEASPPQRWENIPILGELAGFLSQYHDGAASLQNRLSKTARKFASEIRCQWQEGVSQEQRAELRSRECLLYGYGLICRGFGACTSDTELQDVCDLLVLFYNSLLFATDAKVHNMVKKIEYYVSEIMARRIHSVLGYISCGDTSAKLSALCRLVNTQFPSALTWYRVNERSAGRVPSSFEAMNEGQHYLINLATGMVLMDGNLPGSLPLAIRGSPKFVDLFGEQDFEVTYSKGVFSTTYASKGYYYKFAVVNEDLVVEESCKKGSKTIQLCSPEWIEAFKNAFPPRLTEMHSHWYWPRQHCVLLRSRQIDDKSVSFVVKFRGASAICYQVPTVDHAQLDASGIVTKTHTYNSLVVANPELLSVFEKFEDRRYIHFLSSPTSDLEIDFPRARIGFFCGEDNIFTSKDFSGYVLAPSQQLNDSFSRFCQHLVLQDATNDSTRAHYRVLVPFGQILLGDDGNATVKLPNSCSGQFRVSVFDMHPRLNVLETESIESRLQLANIYAASGNFLPSKSLSMTGGEAALVVLRGCVPPRPFSVDAAKQLTNLTSWSWRTPSLKLLAALLAKKSRRLAFLYGEAAALDSIEYTCELEEYAAMCSMKQAQAKSSLRQLLTRSEENELMGNASVYRESRFTRDEARLEPVDLPRIPVNRDVVSKMEGLLLELVSPGKLQVPPPVFPLDHRHSNTMSAHMMEELRDSWDTHHRHPVDRLDISLDGLAKYLVDILARVKEKRDCIHKYLIGSVETAHADWRDQLLKTVNRVPTLTMVDLLRSAIDEDTLLQLAPRLSLAGRKRFRLSVVRLMELCVLEDKLERVIGRARSNILPSLAYFVEELRCRREWSGTEHPYWLVFEVEGRLQIRHEQYVIAKHLLDQPGSVSQLNMGRGKTRVILPMLFLYWSYHSHGQVVRAHFLSPLLSETRQFMHRVLSSGILRLSLMEQPFERQKELTGWDVLRLQEAAREVKLCGGVQMVAPEHRLSLELKRLELEALDEKDTWLVKSLDTLLNNDAYVDIFDESDALLHHKYHLVYAVGTPCPLENASDRWSTAEALLSSLMNPESRKVQALLRELPDQWCHQPEYSDRRGAFNGFRLKASADDLEEYRAKFRRVLVDDLLTNAPFELAWLEVFSSRSKRLRRHLLRFVCDVEADPEELLSKMRGVSSFKHQLLALRGLISFGVLEHCLEKRNRVSFGLPVPGSRPKLLAIPFQAADLPSERAEFCHPDVSIVLTLLAYYHAGLRDEEVFKAFQTLLLLDESERARYYDAWFDSVKSLLSEEDRTLLRSMQNIVLDNAVVVNRLHEVYRYCMGTINFYLNRIVFPRDTRQYPQRLARSAWDLVRGPRNVGFSGTNDNHRLLPLAVTQREPDEPSLRGTNGKMLDLLLQYSIGYEVLHVDEACLLPVWKTLLLMAVKKKCRALIDTGALLAGVPTHDAASFLAERCSSFLGITYYDTRKNYDCWVVLDGARQAVAPLKGSAIHERDTFVLFDEARSRGSDMKLLPDACALLTLGPKMTKDKLMQGAGRMRQLGCDQTLWLTSTDEVQKSVQRSTGADLANLDVRAVLQWVGVSTQEQCTLGVLEWASSGVEFCAKETESKLELKDDDWSLEGQYGSAQTSSFIEAIVHTRVEQFTNGKHGDQTVESIKEMLGGVKARATLYGLDDEVHVSAYGEECERELQVEKEQEIEKIVELSKQKPLSEKDWDYKVLLKARSVQEVCGAVQIFDMKALTKSYLSPAGIATMDWGMTKLYATKNFWPSIVSRSLRTVWTGYLRLIDVMVVFEDGTILLLSEQEADEIIKMLLTDSRHSGGFKVVHLEFVRSAVEACGRDVKYSDVALSLGVSSNGVERMEIRLVDFLACCLLNGDTNLVAKALPGITEEWLRVLLAPMKQREDVLCNFIAARRFAQRWPRSTLHALAMKMDLEDCAIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE07</accession>
    <name>A0A8K1FE07_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE07"/>
    <dbReference type="OrthoDB" id="183853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="206"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="317" mass="35140" checksum="2F96BCBF8A3E48BC" modified="2022-08-03" version="1">MTLRVEVERTRVVIGTVVALAFVSRIVLVFYGGVEMEEIAVQEDARDYTSEGKLIDNYNSYSATVVSLFGRPIGVFIQLVVQLFALRFPSTAILQPETPWHVRGGALCSAAALAYLVNNGLNALNAQLRPLEVQPVISAADLSISMSNNDSWSADEITNVSQVVSEASPGNPISNTVLRNLVLPRIWTQERVCTSAVSTEPLPLIYEGLIAGLKEVQKKGWTPLEVVGSSSLVHQQMSKYKPPRKKRLLGFYAVARRLADSLGVRHWHHHQSEFNRMERAAATHEATTRPIDQAQQHWQRIFRETTRAGKATTGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE79</accession>
    <name>A0A8K1FE79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE79"/>
    <dbReference type="OrthoDB" id="166917at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="50627" checksum="FED9038DA2617EB1" modified="2022-08-03" version="1">MNQAVLEMETSSLQELFKGSVLESPEISVWEASGGLGRRDAESPNAVSQLDMATTIKSGGHSPDLERDSMNEQNLSPLELKRLRNRECMRRSRRRKQDEINTMKQEIAELEAQVHKLQIQKQSQLSTIQTQMTALAPADTNPNDPSSITQLQQVADAIQQENFELRDEIRSKQKFHESIALLLEQEEQRQQIDNQEREFEKHIPEQFSWLQYALPVLSLRSFSPLDVTKLVQESCALILSSAGRADSHMPNSNRVLGWTDKRIVDDKWVQFIFGKDFIHEDLESVVAKSWEVNSNIERINVFQPRLQSMVLLQRWDEDTVVIARNLFVPDEGSDGTEIDLNFCTVMLLFRLKTAHGYIIGTRSLMPETINDSLRLAGEYRTTCVHLCYGLLFTPLAQGFNVKFGGRGGNANQLYVQVCAMDALLAILRWENFCIAPLNRIGMGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF75</accession>
    <name>A0A8K1FF75_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF75"/>
    <dbReference type="OrthoDB" id="167922at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="398" mass="45157" checksum="94C46FEDF4981C28" modified="2022-08-03" version="1">METPTSRWVLGAARTSLYQSKGNQRPTSEDDDDDRTSEKAETPRAASEADKDDGSEEEEPQEAPIETERVAAAGYDVVSDLQRRHDQLQEDVEVLVAHLEKQTHEIESERATMQSMQEQFEATRDAMERELQSLRIENEALRRQNAAVTLERDNAHQKAESAAETHEELLLALKSQQHRDDHARTIVKSLIKERDAARKQLDESQTYCRRLEEELVTNRAELQHMRSENATLTTAAHTATTHKNQYEQRVIREQEQLIQSLRADLLQMEFEFKTLSVDKDRLIDKVSKLQRQSDHPTMYDVISLAAHGDGKKDSKNKGKKQLRVVTSTTTSSDFTNLMTLPNMVDDHEDTTPTSSAKPVAMGNRIRSPMGSLVAKTLSSAKKKLFQTPSTQQTVILPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFA1</accession>
    <name>A0A8K1FFA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START-like domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFA1"/>
    <dbReference type="OrthoDB" id="99575at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="52888" checksum="8C8246B5FDA6C959" modified="2022-08-03" version="1">MKLRLPAHALPELTLTPDEKHWIVDEAQGVIDEALRAERKFALNGRHVNKAEWKLVKSKDDFHVYRERSGGRRRASTSAMSLASTSSSCSSSGHQNMSLVTSGRSLNFSVNSMSSEEHEMLTSSRTSRRMTSTLSAPGDGGIVSSMKESHVPMLLGAGYVRGTIEDSVFGAQSGDDVAWRLRASYMKDKFADARILATVRGPTHEDPFQYLGVKWFTKEQPKLMGSFIQRRDFLIIEATGYKRDAYGIPYGYYLLHSVKLKDVPPLTELDVIRCNVSMCFISRQVEPNNMHIFARGFSDPRGEMLASVGVALTAESILAVSEVGECAFVKKLTWFLRKKQHERHQQLLRTHAFSNCLVTKCESCNGSLMKLLGGMRSGTTSCEACAITICSKCTVSKKLILEVNGDGVVDRELPFCYICVLEAKNLSARDVALDGVPVPARPSMRRTMSCASRPTQHIRRHTETHRKPSVNIVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFV9</accession>
    <name>A0A8K1FFV9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFV9"/>
    <dbReference type="OrthoDB" id="41771at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="152"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="423" mass="48035" checksum="B7B49F1546B7A0D2" modified="2022-08-03" version="1">MGRRAAPLLEMPSARGNTRWRVIAAGRWRMWDVLKLSVIAVVVLVFGWNVSMLSAIVHRPVSSMETPSILRLHEATEETKTTTPPTTAPLLRVEEEKVASVVSTAAVTPNVKKPWFLEPDWYKLETGCDFSEAVRIFDPSQLEINCDNVGQLELGEFLGQGFWRQVFKTKWNGREVAVKVVKAKLMDRGDIIPRHVEEAAAIFGIRHEPNIVSLVGWCNTTVVVEYVPTKLDELVFDPDLEVTVHRALELARDAAHGLAQLHQAPGGPFAHTDIQTRQFLVDDHGRLKLNDFNRVKYTGSCLLPGQSNMKCYSKTSVAKGKWRSPEEYLKLDIDEKADIYSLSLVLWSLRSRVKPFDNLDRETVYDQVPKGMRPDVKAMEDFPQEMQDLIVRSWHHDPEKRPSSLEMAKEIDRILQNYVAAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFZ0</accession>
    <name>A0A8K1FFZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFZ0"/>
    <dbReference type="OrthoDB" id="119892at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="37220" checksum="6A5D2FC483A23595" modified="2022-08-03" version="1">MADDLQEHATQEPEPLASSQSFRVSSAKFHNAKSLRVISGNIRSTHSLRVISGKLHSEVTWVGKVWNRLQVELHGRFSTQRINAMSDYHSRTSWWRAVLVCIVTPLPALFTITALDIAPVKPPTDGSNANYVYWIPIPVLLVFMRAIWTRPLKENPAQLKALHSQLFAFAGQCVMTYSHALYFFAFTSMTRSQQSIFIFGLPVLKICLKNYISRMLRRLEDVKPAFILFNIDVFSALYVANCLQSSQSWINTMLIMLVDIVQIGVSITDIRAINREIRSLTPTSEQSISLFDLYQMATTSPESQKDPHAISTVVPSVQVAPRGPNAESFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG45</accession>
    <name>A0A8K1FG45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HVA22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG45"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="50650" checksum="8095CD2FF83E108B" modified="2022-08-03" version="1">MVLLGPWTARQCCVGIGCVYPLYKSSRALRRQDKEEMLQWITFWMVNAFFWAFETIGDTIIGWLPLYYEAKIVFLLWLVLPSYHGARELHRKWLAPTFQQHEEVIDLTILQMKRRASEKVMEMCKEGAVLAMRRGSGVVAQSQQYVTAQLVQQALGKLQTPPGSTGESQETRLPAVLTTLITTAMTTSVTSVTTTSEPKEAPKPPRPSRTGVLVPVPVVEETNEEEETEELKSPKAQEKRTERQRSKAEKPQLEKPSKVKSVDDKPASPKKSAAAARQEKSKELVTHFKKLLVKGFQLKYYPSEGVIKHRTLRLDHAQSRFLIFESASSTTDASPPKKTKCVKLFIHNARRIAAGLSDSDMETLGWAAMGDDLDNNLLFQLDNGKTTLLFEAESQKTRDLLVAGMRLLINEHKRQDTAALTTITMVHDKLRKQEAFDRLLYSVTHPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG89</accession>
    <name>A0A8K1FG89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG89"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="433" mass="46427" checksum="2866E367E40F1AD0" modified="2022-08-03" version="1">MGAEASFVNQDLVAPAHPVVAIDKRLCHDRAISMLIPQDILHHPSHGAIYEVGKGEFGQHGVGKHGVTQDLTGHNTTGHNTTGHGMTGHNTTGHGMTGHNTTGHGMTGHNTTGHNVTGHNATEGGVMHNLGEKLTGHHDTHHNTTGHNVTGHNTTGQGAVQNLGDKLTGHHTTQPASVHHPTQTAPHGAGQGVFGQNEIRQNELPQDAMHQQTHGLGGHNMLGKDRKGQLMFDFASLGIKDKDDRVLKDSNGKPIVYLTEKNRVIMRNFAITRDSDGYDKIFDVKRKHLSKSPVRAEFKDLASGRTCRLGAAVMEEAHGITALLWLDNGDGTKQKIPVGRIHLPTGSSAHPNVTQATDNHHKVTDAVRPVEHQHKDHGDGYGKDYQLDLMPGVDSGLAALVGMVTIACADHKRRHGDSDTAAVTPTPVVPHNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGQ4</accession>
    <name>A0A8K1FGQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGQ4"/>
    <dbReference type="OrthoDB" id="2017405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021475">
        <property type="entry name" value="Pants/Emi1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052:SF1">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11326">
        <property type="entry name" value="PANTS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="37363" checksum="CE0AFFA449AEFD81" modified="2022-08-03" version="1">MSAKPVSSCLTSSLSQRFDDDILSDLDGDEDDIIQDDEDEDVDGMEFGEALERANRQTKQKQKIPIPISVLGNSRGKAFRPTSAPVSRTKPTAQLGLSNKHFQHTKHNDRSVISITYLKEAAEKKKQRDRDFARELLREENEYKRKMTQKIEHANKMSSAFGSKRTFSLAPDRDGLHMIRVTDPESTDRVISVENFHILSLQLAESTSTTMAEANANPNADQAKRYIQEFYKSQAEEGEEKKTLSCRWFLDRAFLCVTPGNQMTHYYRYGRADECKGTWTNMYDCFRASLMDDERRLEYLKGTDLDPTVPPHKTDVWEEKEKPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGY9</accession>
    <name>A0A8K1FGY9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">arginine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_002256</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGY9"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000116">
        <property type="entry name" value="Arginine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.70:FF:000002">
        <property type="entry name" value="arginine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF5">
        <property type="entry name" value="ARGININE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="15">
        <location>
            <begin position="222"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="14">
        <location>
            <begin position="682"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW63315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="799" mass="88720" checksum="E030A982A8E09489" modified="2022-08-03" version="1">MADLRVAQTDKDLEDMKLLISATPAAEELKCFITLAHVNAAFAVGPSDPKYASCGPQIVLPGAENVIFSANAVCRYVAAANDSLQYEDLAVDEWLEWESHVLTPFVLKGKKAADKTGLAAELTAILEAKEEARAKMDALQFLFGSELSLADIVAGVTLREALELIPADQDTEILKKFRNYVEQLFKVGSFVQGAALLASGGKPESKLDTEVLKGNTSHNVLSIVSSIFEEAINTAFPGLDLPTVEVTRTNVKNAKFGDYQCNSAMAIFTALKGTPNAAKSPRDVATAIINAIPENGLLERLSVAGAGFINAFLSETFLNTRLCNVLQKGVFPSPVKPTRIVVDFSSPNIAKDMHVGHLRSTIIGDTMCRILEFQGHDVERINHVGDWGTQFGMLICHLMEAYPQWETEMPNVTDLTLLYKAAKERFDSDEEFHKRSKHHVVLLQSGDPQSRKVWTTLCDISRKEFEKVYTRLGVKLREMGESYYNSIIPSVIEKVKAKGITSDSDGALVVFTEKFPQPFILVKGDGSYLYGTTDIAALWYRLNELKADRLLYYTDFSQNDHFKLLFEVGKMSGILDPTKNRVDHVGFGTVNDESGKRFKTRSGEVVRLVELLDEAKTRMKEQLLARIESGQTSLPADQVDYAAERIGYAAVKYFDLRQLPTSSYIFSFDRMLSTTGDTAVYLMFAYARLCSIIRKSGVNMEELVKTSDKVLKPVHPTELALAVELLQLQDVILFVDKDLNSNRLCSYLYTLAEKVQTFVTACRVIGSEEQSSRLLLCDATLKVMHKCFTLLGMEPLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHI7</accession>
    <name>A0A8K1FHI7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHI7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="432" mass="48880" checksum="E7C12AF404519331" modified="2022-08-03" version="1">MAAEEGDGIGAFLSATADDETLAAALSYVDTFEDHVEPSMSASLPRNDVTSLANDSLPVQGSTKTTRKRRQRTTPKEELEYLRETVRSLESQLTELQGKSELDLCDAEQKAWKRMTKRHREERQRAEVENSRLRSRLEDQLRLIKSLERILKSRRDEELFPSGAAKRWRDSDRTSPLDSIVVEEELKRSLDEMYDKANAVFGDSRFKSRERECSPVNPTRVMELRPDPLVGAVIETLETSLFPFTYQETADVIWEFMSGQVSRSTALSLMQYDSVSSTSDPSTKVFNGRLSILGQSTTIRAKLVCRRVIESDRVILLSTILMDPKTVDMRSPDNLYLRTRMWQSLRAVSLGDASQSAATVREFFHEAAPEFYGLDDDDEATVDDTTTSDAREQAGVLTTIIQKGLGSHLDVSIQQVENLLLDRLTKLKIHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHJ8</accession>
    <name>A0A8K1FHJ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHJ8"/>
    <dbReference type="OrthoDB" id="164313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="551" mass="61530" checksum="04BCBA8E0630195C" modified="2022-08-03" version="1">MHDGGFRQQPPPLKADYILGHSPSYAKTEDASSSYLAPPQRPVQESTVRGRFVAGEEFFNYDAMGGLREGLHAVELMSRPYFGLLVNSVVGGFATIFFQYVFQQLLVADFTAHHQAQINAAKYLLQWPGAFSVFIGLISDSIPLFGSRRKSYMILGWITACVMFVSMVIVFHSASDGTARGYLLLIFGIIAAFGMQISYIASLAMTVELAQREHLYQRGHLQSLYLAVYFGFSLIAQIVAAYVLKPSDDGVSMTATIDLAEAAAILAGICVVPVPFLLFCLLDEHTDANRVTVMRRVGELWQLLQWKVVYKILFFLCGSMFFSAAYDESVQTAVLLWSNIMPSKSMWVYVVKMIGKFLAVVIWKMWLVNYSWRRLGFMVLTLSVVANIILAVPTIYDVVRDEWYLYIWSIIADIPFGCFELFVLIAPTEIADIGREGAVIGLVNSFMVLIVIATFTLWESISKAAGMEVDVIEIMVDTHEARTSVMTNGAIYIVINLLGIVMAFFMPNQKLDAQQQRAFGGYNRLARTVLIAIFVLLLTYDLVANILKITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHK0</accession>
    <name>A0A8K1FHK0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005439</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHK0"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474938" evidence="7">
        <location>
            <begin position="19"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="299"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding 8" evidence="9">
        <location>
            <begin position="476"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="10">
        <location>
            <begin position="556"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="716" mass="78757" checksum="891D130E1CC427AE" modified="2022-08-03" version="1">MLRRLFLIAVSAAAVAYAAVPTSEICKSAEFQALTLLQVGKSPLLLRSLIKGDQACLEFTLASTVPSNTEWFAVGLTATASMVNTPYSNVMLYRKSVGVPESYSIVGKDRSDVSKEANQKFFVVHEAKTEPLKFSYQRTLAAASEYDMTIDPIQDMEFVWAYGSSWPISGHKGGTIGVEKYNFATRVSSSVSLSPIACSGARCTPIAGGVALLFMLVFGLLFTSVFKETKFARTLLHKTLGTPPVKSTTNAPIAGPWTMLVQNLADLHIGELVIIFIFVLAVGVRVLMAADESDIVKSGHAALLIMKFMLLPIAKIPLWTVSFGSSFERVVKFHRWLGMLLSVITLIHLIMATDVVDLTSSEKYNEVVPLWGLLAFITFVAIGLTANEFMRRMFFDVFYLSHRVLSIMGFVFTILHAPKEIGVALVVPLVFYALGLLSQWFKSYSTTYQATVSVHEPTKTTTLELDSTDKTKRIAQTMNLCSYFWVRVPTVSGLEWHPFSAIVTPHRDSIAFCMRAMGPNTKSFTAKMLEQSKSTYALSVNLCGPFGKISLDVDAYDVIVLIGGGVGVTPLLSAINQRRLFAAKSTKSAEWNILWSVRYPDDLLMTDKLMPSGDSIDSASSIQDAYVPLTSDGAGLKVTWYCHCSEEKQDGYVPRANGEQIGYRAGIPVLDEYINSSRYMGRKVAVLACGPPTMTVEAQALAQKCGFDFHKEVFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI23</accession>
    <name>A0A8K1FI23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HVA22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI23"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20399" checksum="5C79EFB3894BEEA9" modified="2022-08-03" version="1">MSFYLISEGLTCLGMFNGAYESLKALSRAEKGIEVSTLTQILEFWIALGALTIFEEYAEFFVSWIPFYYFFKCMLLGLLLVPSTKISHVLYHGFIEPTMDKIQEQVHARVLPVVESLVVQHGHWFHERLLSRSLTLLDDQALNEYEQELQTKLQDVRNEVRERRQRPGKEHSEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIZ8</accession>
    <name>A0A8K1FIZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIZ8"/>
    <dbReference type="OrthoDB" id="424220at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="6">
        <location>
            <begin position="250"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="37074" checksum="8F29A62C5646B989" modified="2022-08-03" version="1">MEQGIEALFTRRYPNAVEMFTRVLGDTRGVSERVKCWIYRMVANLRMGNIDAFQADLDCMELVGGANSASLLGLNHLWEEITALRQTERTVFSVRQLMARADHFFTHRDFESALQLYQEVVSTETSRANQALRVCQAEAQFAAAKCMVMLDRPEPARASLEAVLAMDDVSVEMEVRVLLWKGRCMHQMRRCNEALETLLRSFDRLRAAPECPSAAWLRQCLLTEMRVDLISRCDTALVNLDGPQDATSQQTLELLRCPLSLELMEDPVVTPSGHTYEREMIERHLDLNGQFDPMTRTPLTKTQLSPNRVVQQLRETLLNNACHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJN4</accession>
    <name>A0A8K1FJN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="8">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="8">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="8">PHB:PPT</shortName>
            <shortName evidence="8">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009283</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJN4"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000003">
        <property type="entry name" value="4-hydroxybenzoate polyprenyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="40383" checksum="1418BA3ABEECC6A8" modified="2022-08-03" version="1">MSSVTPALRSRVFHSAALFQRVTQSTGGDALVVNKLTQGKQSSLRWDTSRAWMSTATPPEEKDAEKTDDAFKIEKNTWAERHAPKWMVPYIQLARLNRPAGTYMLLWPCFWSISLAAPAGSLPDLGMLALFGTGAFIMRSAGCTINDMWDKDFDKQVERTNQRPLASGALTYPQAWRFLALQLSAGLGILMQLNWYSIALGASSMGLVVAYPLMKRVTYWPQAFLGLTFNYGALLGWSAVQGSCAWPVCLPLYAGGVAWTLVYDTLYAHQDKNDDRHIGVRSTALLFGDNTKPILNAFSAAAVAGFGTAGYMVGLDWPFYAGLAGGAAHLAWQVNTAKLDDPINLQTRFASNKWFGALMFASIVAGKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL97</accession>
    <name>A0A8K1FL97_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL97"/>
    <dbReference type="OrthoDB" id="120491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="50270" checksum="C685BD46E074FF73" modified="2022-08-03" version="1">MQWTYPLGVVFKSTYWLLDVSIGRWLAVFSLILTLLPITSSFLMLRHDMVKLLLWTYEFWYITVINLVCCVFVGLEFGDWRWCAAVMVTLGNQNTLMIDANFRSVSTTIVASTAAAVMLVCFIVYYALGLVDATQTVDLIQYNGWSLRSSDIASNGLGTLLLILLRNAYRRFTHISGMDKSKNLVRCISYRARVLYVPVEPPAALAIQDQETTGTSSHKEEEINCSTRLQFVPVPIVFKSTSVLGCVGSFSVAGVTLSPIATRLAGWTATIRAVSAVAAITLSTSGTLHAILSQIALGLSSMYCIVSYLHHNRKMLRLLFASFDYLFLSIQLLMTQLTIGYLLRWNERCYLVLALWLWGHWVVTLDAMAPDAKSKLGISRWLVMLVVAVELAGLLLLCSGFTVRMDPSYEDRVVLTTLIHGNPIEIHAIPFLFSRLFAVFLWCLRLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLI3</accession>
    <name>A0A8K1FLI3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLI3"/>
    <dbReference type="OrthoDB" id="5806726at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="253" mass="28823" checksum="9E8DF3D696A9C045" modified="2022-08-03" version="1">MRGLVEDISTQVIRFKNVEALEIILDSDLFNEVLSPKERKLALECMQRSLWWYRRDTNFLRVLIAHGVDVDKFTRQTPNRSFPYLFFGATAVPFFEELRRSGVVGLRSTTLGSEVWFEDIESARTLISWGVDVHGKPSEWTPLHSAVMTSSIEMVEAIITHSYVDVNAPGCNYPSRFNDGTTLLYARVAKDLRLQEMSVDKLDLLFSYGADPYIKSAKGISPYDMLMEHEIGRAYVSANEPGFPTDHKKKTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM8</accession>
    <name>A0A8K1FLM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005883</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM8"/>
    <dbReference type="OrthoDB" id="167576at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053033">
        <property type="entry name" value="Androglobin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054094">
        <property type="entry name" value="Androglobin_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46298">
        <property type="entry name" value="ANDROGLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46298:SF1">
        <property type="entry name" value="ANDROGLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22069">
        <property type="entry name" value="Androglobin_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="3">
        <location>
            <begin position="364"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1015"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1222" mass="135842" checksum="9B3777977E2BBBF8" modified="2022-08-03" version="1">MPPRKPPQASSQKSLQHVNGPTPSERQPLPPPVQPEPGTVAPLWTPTGVPNEIFPEWPGAAALATENWFSEDAPFEDAISLSAFPLPSSGDTITWKRPREIFTPIVEASPPAAALAPVVPDPKHAKKPPAPAAKKGEPEPPKKPPPAWYAHIVYVEPPVVHHEPSAHLPPPSSDPRKAAGASVPPTPAPILPIQPPPRRIIRDFRRLWSPEEFTRLTQWKKEEDRIEREKENRERVYMEFEDATAFIINDRPRGAYNEDSVSPDDLVDDGGDDDLEHDEADGDFGAQESLLYGVLPPPRISITENAIQKPEIPHGSVVNADIASYFRVIDQLYEQFSQNSDSPFLWEAIYPQDTHGIPIYNAGGKYTVKLFVMGKWRRIDVDDRLPVDEEGHIVFVSSYMKNEIWPSILAKALLKVFHWQFGNVSTVQHGTMVCSFDATRFTNSAVSALTGWKVSRCDDVLIPGSDYLQIFSQFVSPQIQNSLIVEEETDQLDLSAPEEVMDSDATTRSRVVLSCENEQGASGLAFREAVLLNAIVGDTGSVIFKGTNLNGPMSVAEEDLTRFRLGFLLVHPPSAFSDFVEVAWTKSPEGEHVPFTNAPSRVFVVELASVPRAGAEQSPGDSSSESAPIASPEFVDVIVTLTQVTSTSMPTQPNEARLIEPPPPADPGSVILVEDISYRNFQQKKQDQDSQFVDSAPLVFEINTFSSTRMRLPANQQSRWGFRVFPQQSCCYGYGIQIESQVKVESHFSSTYWRDLWGLQVIDGDGSYPAMLPFSWNVLFKQTIEFSPSDSVKAIPDVLVDLQISEAQVIPYVHISMINNQTNEVVQLAGLYSQVALPVGPDSTVLPTYTIVVECTPGASTIPEGKWRLTLGSSMPFKQASVHQPRMTAFGGTYEPNKPLICFRDVMIQPKKTAATSLDVKFVDEANEIMEDLTVKLQVIDLASQQVLSEVHGHGIVRLLQLPPYTKAADDPNEEKSGYILQGMIDKGHCNVPDALRSVRPFRNRPPHKEKDLTLTATSEEQSTDESTGNNSSVEPQIRLKWRLTCWSVDEVKLELDRTEELRYEAIQASWIEAAKGRDTHAAASRLLFLGKTEAAEASMRGDSVNDELMAKYKARLEWLSSASNTMSDGPYLDLLPEVDPTQDILRPENSFDNDDRILNETIESAAHFLQDIREARAGAKDARAQQLKEFVQSVKDRRQDAHAYRQTLYQERDEVLKSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM04</accession>
    <name>A0A8K1FM04_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM04"/>
    <dbReference type="OrthoDB" id="10684999at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="468" mass="53983" checksum="D7302E7228AD4984" modified="2022-08-03" version="1">MMLWGVVADDSLLFRLCLYVGVALILFDTVVPMLFRRRVKLVWPRRARPRRLFPRAPVLPREEFRRRKRALEEEIRVLERREERRAKRRSRRREQPRIARRLVDSAMTEPIVPVEERRRTPKQRRVSFHEAEGEELLPRSMRKAPSPVAHERMNSADYPHVAESHSPLSHFEPPAHEERPLPAFRSGFAPTNTFMTERDGAGSSSPLDSRRADPLSVLDNDFPWRLPNYAPLPDPVRQPSPFKMNVRRPTQYNRSTTTSTASLASAPRRSEYDDLFTFRRPATGAVPTAATQSEDTEVHADETHPAADFSREKPSPSPLAKRSHEQAFGILKRRMASPKPPLAQRSSVVSSATTSSQPIRAKSPSPLVSRVAAQPPQPRLKTPKIVRRITFDDDMMAMATPEASPASSKRLREAQDDESQRREFQRDSIDLPETQKRRVSGEFNYSEAEEKEEQSIHDDRRWDTWRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM21</accession>
    <name>A0A8K1FM21_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM21"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="16"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="37092" checksum="881E2B8B0CAC938A" modified="2022-08-03" version="1">MAAEPRTVRAFAAMKAGLTVETWEYQAAPLLPLDVEIAISHCGVCGSDVHAITEGWGPALGANNYPMVPGHEVIGTVTAVGSAVTDLKLGERVGVGPAVGSCGECSECIQGKDAYCPKGVFTYNGRRPDGSITYGGYAEYMRLDSRYAFKIPEVLPSDAAAPLLCAGVTVYTPLREHVKPGQRVGVVGIGGLGHLALQFIRALGAEPVAFSQSPNKEEQARELGAVDFVNMANPAAFGKAQRSLDALIVTADAKGQPYDAYLSFIRPHGVFMLVGAPEDNFSISPFSLLASNVTVVGSLAGSRRDMKDMLALAAAKNVRPVIQKLPMKDANKGLQMVNEGRVRYRVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM31</accession>
    <name>A0A8K1FM31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM31"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36657" checksum="F683AEA39404346E" modified="2022-08-03" version="1">MSSLAAARADNFYYPKDWRPEDGSINKFHKSHPLGKRAKDIKDGVLVIRFEMPFNVWCTHCDVHIGRGVRYNAKKKRVGKYFTTSIYEFRMTCTNCQGELVIETDPENRGYKLVSGVKKQTTVDDVEDKAEDTGIVEEMETERLNDAAVGLQLAADPFFKLEHEQSDKRRAKQRAQGIEAIQHVQDAQYRDNYASNAALRAQFRQKKKHLKQNADRAENLGLGITLVDAQDEDVALSKAMVFKGIQNKRRSSADKHGAKRKPTKRASEDSFQHFGDTMGSQLHRLKRRKQEERKGARVIKPVAKSGGDRVAGRAKKLLLQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMV7</accession>
    <name>A0A8K1FMV7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMV7"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="866"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="952" mass="107505" checksum="DB6285DC829463D0" modified="2022-08-03" version="1">MLCRRWYFTSAWLQYDLRRPLHKKSPLNLHSRPFQHQWQQFIKANCKVFLDRLVQFLPPASKEETYRLKMGLCKSTNTGVRPSFDNANARTGYIVDKMNRCGNLPNVLLTEEMSDMRTDLFGSRSSRHWKVALYGGGPGFDSIGLEFLANYLRVPDQTFETIVYDNEPGWADAVSGVRRTLETLGFSRSSWEFKPCDITEDLTTAMNAGVGADASSTDLFVFSRHPVRVAVRRRRRKRELSARPRSAHKQHPGQTWSNATSPNFNPTLMTQPSGENSSADEVTAEQVYVKLIRKILTEEPRAHSDPPTINPAMVNVLSEDAALGVFLSYITRLAGHNVEAEPVLDGPSDKPFAGDVVELPTSDRGDSATITPELLASYRATMLLTSDEASEALMTFLAKKTKVIVKCVFPIFQKNSRGNLRHGCRVIDYLMRLFVDDVYDVIGRSSSIVKRYMGSMLQYIEHAPVAELFLTMICKPHSATVMRFYQATPQKKWQFFRSLSEWKILLVLAEHVYGTSYTEEHNIGAADVFVELLDRLSADENGAILLQPAAYCPELLENLIRTAVDNKLSRSAGQRTAAMKCVLRLLQRSMLEKVQGPPTSPYQSFGGTIVNLVPNQLASLREKIFELAEKDMAIMLQYMTEKYQDQQNIQMDLSSDKPLPDSAVRHTAYVVKVPFTEFRLMLVDALVELIAHNPVKMHDHFDVNVWRVLVAWFFEYAHNNLYHAAFYQLVFIALRTDNKATLAILMKKLKLVTSLIENYRNEEVSSSNKGYILQCCNAIRLQAASQSPDAFLRSFLQSHTTWRGFEAELREQTNRFCVPGLGFTVPQHMRPGMYQPQDTWQTIESSDKGIDHGSEFARSLGFVDDVAWPDDHTGSENGRKKKKNKKKGKKKSGATNGEEHEDDESEGAFTGASETGSEHGSTDTLDMDDLTNTTSGAPKKSKKKKKKSKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN43</accession>
    <name>A0A8K1FN43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN43"/>
    <dbReference type="OrthoDB" id="160810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58073" checksum="2B3C95D4AA9C4B69" modified="2022-08-03" version="1">MVRIRNPYASQAPPPASPALKTQRYAVGVRVANPLEGRMGSIASFDAEKGVYHLVFHDGHEEDVPEDQVDALVIRQPQPSAEKTAASEGFTMVGRNTKKVVTNYEGKELVLMGWVAAYFPDTKRCRIVYESGTCEDMPVEDTKKCIKAAEANSNGKRRASDEGDEDATRKKAKALDDELQKPPLNAQKFPSRPAAYTILRKVLRAILAQEMAKKHRTEKQLSVLKNEDIKPKRALEMFVEADGLSLLQKLLTEWMRSTETHPGASLVLKLLAALPGVTPDAVLASQIGKTLSGIVRVSKEMDHVDKMLGDLASWVIATWRRNVVPKGVSNLMATQHAVERAKGVLPALVVLPIASQARLKERHEMTKHLRELMTAPEPPPKETEPALFFPEYNSLGSIDKRRPARQIIHIESFLERVSNRLNDKTDEEEKDDGIPKGRMQFRKPDVHQFNPNVPPANLFATARSRALDAQHQRLILDEDEIDAVERGAKMLPPPNRTQAPKKSILKATEEVIVPAKDVIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN60</accession>
    <name>A0A8K1FN60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN60"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="253" mass="27906" checksum="E2128B3C178A7E8C" modified="2022-08-03" version="1">METPAVRVLVVGDSGVGKTTLLQGVCTSAANGVERESAKQAHRWTIGCDVHLLLHHYRDGYGMTKETYIEFVDVGGHPKYEISRAMFYHDVQGIILMHDLSNARSFDHLRQWMTEIQETQRRKGSVLSASFHQRTADAPTLHSLPKLIIGNKRDLVARQSSNKRLPTTVASELRGIDTLEASAEPFALDQYAFGGFLDRVVAFANNQGVESSQGHDATYHPASAFSDGLRQMKGKPGVSPSPTALNSTGSWWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNI8</accession>
    <name>A0A8K1FNI8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011558</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNI8"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436333" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="30"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="27083" checksum="6F42622B6D0B0655" modified="2022-08-03" version="1">MVSVISKLAVCAAVMATAGSALEVGEYYRPTGEEVSGVAGSTTEYARSPCPALNALANHGYIARSGKGITHEELQNAIVANYNLDASVAKALASRVPASLSLSDLGKHNFIEHDVSLVHSDSVYGDDPAALNQTLYDDLMSRAEDGYLTLDSIAAARGSRIDACKARGDTCEFGTKQRILGVLENAILLRCLGGFNEERISVEYAQSFFVDERIPDDFHKSETVVSPVKLILTATKLESKVTWSDILEFFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNW0</accession>
    <name>A0A8K1FNW0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNW0"/>
    <dbReference type="OrthoDB" id="43153at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="40801" checksum="6661E8AB5A6FD0A9" modified="2022-08-03" version="1">MKMQLKKRSRASKAAAFMQMSADSKQQSRDKKDQNRRRMRVIQLQRSLERKEKELRAFPKHPVPEKPKREKGPLQPHEWKLKGAARPAAMLARIAAGELDQEGNEIPKPIETFDLFKQTMQEGKMAINPNTREYLIIMKQLADACCQARMSDRGIQHYQKCMKLDKEDTLRSREGLACALIDEGRGDEARALVDKYNGSASAVLAYCRVIIEYVSWEVLEEKGSSEEVVREAFLKAFELNPFIAVFIAAHESFFQSVEYIEDIKDPKVGSIEESFVYCANNIGVWLDTVGACAWIEKELAELPEPVATAEHCSDEMYLGMYETAVEMHKEALAEGEDDEDASEEEDEGDDYDEPEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNZ0</accession>
    <name>A0A8K1FNZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007501</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="776"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="878"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="950"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="92"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="407"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="735"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1297" mass="143885" checksum="FAEA62199F36D625" modified="2022-08-03" version="1">MTSTYATFAAPDASSGAFKHPQTQAWCLSRLLLAWVVPLLRLGHRKQLDADDLWPLQHKHRAGVVAAPFRREVERSQSIVRAYFKLFGGRFVLTGLAFFIATAATLAGPLVLHHVVTELTVDTYDVQELMTWIVGLFATQVVQALMENYARFDSEVIAIQFTGALKNMIYDKTLRLSADARLDYFVGDITNLYTTDCQFLLMAASSVHQFWLLPLQIACVTVLLYRLLGLASFAGFGVIALAFFLNNFVSTKIYARYIDFMECKDDRMQAVTEAFRSISIVKFNAWEDKMLARIGEERARELKNIWGFLAYSGASVVLMWGLPVFISVVTFSVYSGVFHKQLTPAIVFTSIALFQLIQIPLRMISDMIAALVKAKVAHGRIVAFLDLPEVDTDSVRSIHHPDADSHIKQNVIVAFKYGTFGWDYDSPILRDVNLRIKTGEFVVVHGPAGCGKSSFCAALLGDMANIDGSLYVGGSVAYCSQQPWIQHMTVRDNILFGRPFDRKKYEKVLEACALTKDLQSLPAGDRTEIGERGVNLSGGQKARVALARACYSDAGVFILDAPLSAVDAIVQNEIFQKCLLGLLRNRTIILVTHNPEIIASEHVTRAVTINEHGELVETRAVETRPEYKSVVTPLAAKAYVKHSYDNEDDDSNEAAYKTSTADDLKYAQLMEISTGLTSPLRQNSVSYIDEKADNDMKDATETHWLIEDEDQNVGRVGGGVFLSYYRAIGGFPILFIILVSQVLWQAFEIASSFWLSDWTNDASATEDGMFSETFRIQVYAGLGLASALMVVVRALVVSWSGLGAAKRLFDRMTYSLMHAPMKFFDANPIGRILVRYANDVTDLDLSVPLGFGSFFACLFSVGCTMAVTAVIIQHNGLFLIPVVILYIVVASFYLTPAREIERVLKTMEAPVVSHLSETIEGGHVIRAFGQSHVDRFKLTNDHKLDSSNKVWFAQLCVSRWFALYIQLLGSVLVFGVAYSLVLLHASLSSAIIGLAFSYVLKASQTVGNIFQAWSTVETTMVSPERIQQYIDVEQEAPHKVPSVDPPASSEWPSSGAIGFENVSFRYKEGDRLVLQNLNFTIAGGEKIGIVGRSGAGKSSLTMALFRINELASGSVSIDGVDVGKIGLKTLREKLSIIPQNPVLLRGELRRYLDPFDEYSDDALWSALHRVGLSDRIANDEDKLYCMVEEDGENFSVGERQMLCMSRALLRESRIVIFDEATASIDRETEQKLQRVIREAFVGSTVLTIAHRLDAILDADRILVLDGGEVVSFATPLELVEKGSGHFYELMREGGYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP93</accession>
    <name>A0A8K1FP93_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP93"/>
    <dbReference type="OrthoDB" id="96297at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="226" mass="25102" checksum="D6196257A7E51243" modified="2022-08-03" version="1">MLKVYNSTITQWDDTDGALTSEAHPLLRSLQFVLTNFTSSKLPMGLWSARFPQGVTVIEFCVTNLVELPPLVSLRWPHQIRLAWEGSPLASVPSVLYELNLTQLSLARNPLTSIPTRVLRVPTLVAFSVAHTAMIAFPSNVTLSPVLEQLSIVKSAVSEMPSWFYDDLMHRPVHYLSEGLTLFAGESPFCESIASQTIENGERIVCASVRDDVSYPLDQEDAQSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPZ1</accession>
    <name>A0A8K1FPZ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphatidate cytidylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_011017</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPZ1"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46382">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46382:SF1">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53597" checksum="8829D6AA8F3F83C1" modified="2022-08-03" version="1">MTYRPNDLTLDVALDNMHELRSPTSSTCTYDVMSVSTEEDMHMAQWREDAPCLRRVGKRLQRALGSNAVQRVLSACLLAPLVTVFLWFSPAFATATICSFVVSACAYEYSWMVHRIQFRFLALTECPSNAVPGGSMEYFNDFFSKNGDTKDIEQGEEAHQEEPDNEIRHAMNLQDCVITPIANRYFAGAQRFTVVLLAIPVAVAISAVFQALLLLMPPSFRESDFYTFRWLYSLTTDFVCALFALHTPNRRSAFVVLVEKAVFSFITVHSGMCPINELSCGNILSATDICAIGMLIVIIFHISLRKQALHTFVYLFLDLLGFIYLIGTMSVFIGFIDDSRRGLYRKLLITLLYVVWASDTGAYVAGKVLTRVGYTKYHAIAPHVSKNKDYEGTAVAVLWGIGTIFLVSEVIGVSAISIEKSVIAALAVVVGRMGDLFESLIKRAAGIKHSGSLIPGHGGVLDRIDALLFASLVFSRYYTVLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQW8</accession>
    <name>A0A8K1FQW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQW8"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF22">
        <property type="entry name" value="SLL0786 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="17277" checksum="ED0071F6B9B50193" modified="2022-08-03" version="1">MTLLVTRVTTPEELAIAKAIRFEVFIDEQGFDGSIEVDEHDAAETTWHFIGKDVEEDKYVAVARVLLTPELRKAKVGRVAVLKECRGKNYGAVLMKSVEDAVADQVDTYMLSSQYERRGFYEKCGYKRMDDEIYLDEGVEHCMMIKKVVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS43</accession>
    <name>A0A8K1FS43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF83">
        <property type="entry name" value="SOCS BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="22"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="199"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="232"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="298"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="430"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="493"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="526"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="559"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="592"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="649"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="682"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="715"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="748"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1996" mass="217778" checksum="2BB77A3E8EC8AD94" modified="2022-08-03" version="1">MELLRAVQKGDVKQVERLLKRADVGKLLKATDCGGKTVLHVACSNGRLDVVKKLVAHGAALMAVDSNGETVLPVACEDAKANVVTFLLSQGLDVNAVDETKWSVLHSACDGGDLDIVKLLLAMGADLNALDEDEKTVLHAACQSGNEEVARYLLNRGLDPKAVDNDGYSVLHSACEGGDVDLVKLLLAKGVDINAKTKDGTTVLHTACEEGSSDVVMFLLERGMDVNAVNDEEYSVLHAACEGDDVDIVELLLDQGANLNAVDKDGKTVLHAACKGGDTDVVKFLLSRGLSPTSVDNDGYSALHSACEGGDIDVFKLLLKKGADLNAATKDGTTLLHTACEEGSDEVADSLIARGADVNAVDKEGNSVLHAACEGGDVVIVKKLVKKGASLNAVDEDGKTVLHFACKGGDKDVVQLLLTNGADLKAVDKNGFSVMHSACEGGDLDVVKLLVSKGVDLKAVAVDGRSVLHGASGVDVVKFLLESGLDVNSASETKWTPLHTACEECEADIVKVLLEAGADINAVDEDDFSVLHSACEGGDVQIIKMLVEKGANLKAVDSDGRTVLHIACNFGSVDAVKHLLELGVDINAVDNDGWSVLHFASESGNKALLELLMLKGLGRQESLRVVHSDQDGAAAATSPVFDAYTSSKDGQTVLHSAAKSGNVNVVNMLLSLGMDSNIVDNVGDTPLHAAASEGNAAVVQVLLNNGANASAANEDGYTVLQAAAVGGSIEAIEALLAHDADPCTLDNDGWNVLHFAAFNEETEALKFFLNRGMDANTSSNEGNTPVHAAARSHHYRGVDALIGKGCHLNLRNKSGKTPLNLCVQWHEEVAELYASDEGEDDFLSILQTAYSLMSRGATYEAVPGDFTPTSSKYQDQAKIVELCVKHWAEEQKRGKKTITQLPPEVFMRGVKAVQTYLDEINASSDSDLVLRRKVCVIGSSKTGKSSLIKSITTMEPILVAEEDRTIGVDLHHLEFVEVGDGTAPAKNHQITFWDFAGQDEYHVAHTLFFSRRTLYLLGIDTKAFAEVVDASRECDDDDEAEAMIDAFVKERVWRWFRLVFVRQPDAEFVLVATKVDALATEPQRVKELEGTLMGILQEYKSAFDREVNEEMKCLETRKESVYFTADESTLSARIDHLEHMRTRLNESLPTSWLPLDVTKANSIQDARFLIERVVTQSDRSFLMPDKYSRVLEKIQELREEPPHQSTKARIKQLIVPLPELREQLVQGVDDLEPEDCETILETLHDLGDILWYDRDGLGVLGDTVILSARLLIDLVRQIICHDPIKNVTKTRAGARVAKLIENMLVSGQVPHELMTTFTLWKSLEYPDQMVRFKKLLQHFQLAYPADMSSMEADSDLIVPTFWKLREEQMDVLELEPLGDKFRSSLPEPAGSSARVFHWEYDFHFEMVETLFEQLAVQSYSVFSKRTAARSCIESIPNAHYAIRLSLVKENGRQIIALEVAAVDATIAQEFLQKLYESLESVLADYPGITVTRYGVDEDGSRVRIDQVVDTVRAASPAKLQVLRSEHEWLPADLSWYKLPEEKQKSTVAPVKLLRNASLLLALNTKTKLSMPNAGPSRSWQNVLAKVSAQLSSTKLGDVESTPAMPAKLLKLPSGSFRRELRELVRGELDGVKNELKTKMDSVGDKLLQTSAGDGNHRDLPALWMVEYVQKPKARLILWILSEISGRCFHKPIEIAVSRQFLAKHGDKLQLGLSVFSSVLPDAPVVSVVKSALELASPELDNRLAQARSVHDLLGNLGLENGGTLNTSKQQPVSPAGMYGLLRALLKIHDPEFQPDKICDLAKLECGMVLLEGGYRWAHRHELLQAPDLYKLRVEYATDSVHSRGTGGVKLGSDLPGMCCLSDFRANGMGTDDSRLAYCTWEIVNASRSLLSAGETIQNPNDGDVQSWWQEAFVLSGMQSVHDLRDCELVVEVKRPSKLVLRSDRFVARGSVRLADVLPNDTNQVVDQFRIVVPLTKKDGSVTGASIECQLWGVGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2T3</accession>
    <name>A0A8K1C2T3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Poli38472_013311</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2T3"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="132"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="229"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="530"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="1005"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="TMW55420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1097" mass="123025" checksum="92F86A78220D7196" modified="2022-08-03" version="1">MAGTKRVDAADASAAKEQEKDAKRQRLGDDRFRQETAPTFADDLEKMAPIATKASAWPRKPLRKMDPSTDSVAFQWIDIDMYDGPPLARNPKAGEPVPGLVASSTGGNQNAAIVRLYGVTEDGNSVMMHVHGFLPYFYVACPDNFEESRCGEIRMSLEAALSQRDRDRADMTRIVGVQFVTDKMSIYGYQFDRPVKLWKVYLSMPNYVPKLRSLLEGGLTLPGIEHRTYQTYESNVPFILRFMIDQNISGCNWLEAPAGTYAIRGAANKKSLCQLEIDIVYNNIVSHEPVGKWGKLAPFRILSFDIECMGRKGHFPEAEQDPVIQIANVLQVQGESTPLVRNVFVLNTCKPIVGAHVLEFEKEGDMLEKWASFVQEVDPDIITGYNIDNFDVPYLLNRGKALKLSNHAFLGRLAHTAAYMEKKTFSSAQYGKSESVKTTVHGRCMFDLLPIMRRSHQLSSYSLNAVSSTFLGQQKEDVPHGIISDLQRGTDDDRHRLAVYCLKDAYLPLRLLDKLSFVVNYIEMARVTGVPIDFLIERGQQIKVYSMLLRKCQNASLVVPTLARTGDNGDAGYEGATVIEPKKAYYTVPIATLDFASLYPSIMQAYNLCFSTLVAPGDVGKLAKSDYTTSPSGDVFVTEQRKKGILPMILEELLSARKQAKRDMNAATDPMEKAVQNGRQLALKVSANSVYGFTGANVGQLPCIPIASSVTAYGRQQLYQTREEVERIYTVANGYKANAEVVYGDTDSVMVKFGVDTVEEAMPLAEDAAKRVSDIFPNPIKLEFEKVYFPYLLMNKKRYAGLLWTKPEKYDKLDSKGLETVRRDNCLLVRRMVESCLRKILIDRDVPGAISYTKNIISELLQNRIDISLLVITKGLKKTVDQEDYKVKQAHTELAERMRKRDPGSAPTLGERIAYVIVDKGKAAPLYEKAEDPVYALENSVPIDCDYYLKQQLQNPLERIFEPIIGMAKVKSDLLNGEHTRKRSKPGVKQNSGGMMNFAVKKLKCLGCKAPLNGSGALCRNCMENEAQVYTKQLESVNELEQLFARLWTQCQNCQGSLHQDVLCSSRDCPIFYKRIKVQKDLGEAQSSLERFPSVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5D2</accession>
    <name>A0A8K1C5D2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006881</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5D2"/>
    <dbReference type="OrthoDB" id="29061at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055089">
        <property type="entry name" value="COP9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF1">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22788">
        <property type="entry name" value="COP9_hel_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="COP9 signalosome complex subunit 3 N-terminal helical repeats" evidence="10">
        <location>
            <begin position="43"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="314"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="53536" checksum="0C046D4905FACCB1" modified="2022-08-03" version="1">MTSWGPLQPLYAQLLKEEQQQDGEKDRRQADLALARVLNSDETSQAITNASLEQLDLALAHDALAVERKPLCHLFLLSTKSAKVEQFVARRATTDDSVQWLGIASRLVAQVSQFLYQVPVYVASKEIRRVSSLCVHYVNLVVGLQQGIRAVFPLKSFLRRFHQHGNTDVTPIHGQFMYLCLRAKCYSAAMEILDQPLFEVHSQTHLVSAVDVLSYAYYGGLLYLGEKRYQDTIDLFLMAVTVPAVALSAFVVESYKKLLLASLILRGEVEPLPKYTPFVVTRHLEMHCGPYLELSRAFTGDKSVEAVAKVHETYAAVFAKDGNNGLVKQVIEALKQQKLLKLPRTYVTIPLAEMTKAADMEISGDIGAEKMLLQLVARGDMAAVIDKQKGMIKFVLDDDDHHVNNQENELEQMLAMEKLQAEMEKILHISSQLRAVDTEVVTSAKFQSRLQKDKDRRLRGGPSGGDERVGGGPPGLEGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5M4</accession>
    <name>A0A8K1C5M4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002934</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5M4"/>
    <dbReference type="OrthoDB" id="446044at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045900">
        <property type="entry name" value="Peroxisomal_Ade_carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46650">
        <property type="entry name" value="PEROXISOMAL ADENINE NUCLEOTIDE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46650:SF1">
        <property type="entry name" value="PEROXISOMAL ADENINE NUCLEOTIDE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="95"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="190"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW57009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="301" mass="32832" checksum="962273DF129F3507" modified="2022-08-03" version="1">MLAAASAAGVGGLLATSILYPLDTIKTRLQSGGSLFEESGSDDDKKKKQDVVAVIRSFYRGYQYKAAESTVSKFLYFYAYTLLAQIVAPPDGKSIGTATNLAVGYLSEFFHLPLTLPMEVIATRLQTSSKGSGNVLQIIRKVLEESGVKGFYKGFQAYFVLCLQPAIQYTVFERVKTVYLSRAKDAAKSLSALEAFLLGAIARSIATLLLFPYIRGKVLLQSKNKKAAAIEGEAKSNDAKKEEGIVAILQRVYKEEGPLALYRGLTPELTKGALSSALMLMIKEKIQMYITFMLILTSAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5S4</accession>
    <name>A0A8K1C5S4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5S4"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="379"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="412"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="479"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="531"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="771" mass="86154" checksum="6F63C2327B8E262D" modified="2022-08-03" version="1">MEDEAKMLSMEERLQRMLTQPQRRNRGQVPMHEVEAAWQYQRTYVPQFTELDSNAITDCSETLQRLRDEKREARDRRDMTWEDHLATEVRDEITRAATTKAKRLAQETAMLSQIKTDMDKWNMAVDLNLCEYLTATLGVLAADIRCEYLLGRIGAGQTPLHRAVKGRKAAMLSLLLSMGADMTIKDDSGKTAMHLAVEAGAFELFLVLAASLTPDQRNLLTQFDNGGFSLLHAAATSGNVEMVRAVIDAMDPLKVPVLLNQQTQKEKLTPLHLAARLGHDQCLRFLLRTPGTRANLRTTNGSNALHLSLEQTFNIDTLVQIFLECTPSQGENEEDAFQAVDAVSGCNCLHLAILKNYRNVSLALIRSRRIELNTATRDGAWTPLHLAVMTEEIAIVRELLEHGAMVDMVDQDGQTPLLQACLGGQLDVVQLLLSSGANPAHQNKQAHSALHYLAAFCRDRPMLVDLIGRGADVNAKSLKLNTPLHFAAMNGNEVATEVLMTHGANVSAINEDKHTVVYLAKKWRHRAVEDLVKPPEEQAATPDSRPGTAASRSHHQTRNSHHPTRRETGMGSHSPSPGSSSIRSRTPLTTRSDDSDACSLYSFDDEEILAPSTPWPGRVLGEESNNGRNSIQPARSFAELCLRFDRREAVNGANSDKYPLKPLLHAQTKPQHRIAMQVAREIVDSTMRKQEFTRFTRRLLTSPVHIPWEMTVPLSGSLLHSSTSDSDLQRRLKPSIRTNIGLLRDHLTHAQELNWPRYANQRVFRKDPLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5S6</accession>
    <name>A0A8K1C5S6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5S6"/>
    <dbReference type="OrthoDB" id="5824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05266">
        <property type="entry name" value="SDR_a4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43574">
        <property type="entry name" value="EPIMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="69098" checksum="8BAD7843B899C0B5" modified="2022-08-03" version="1">METKKLFVFGLGYSASRTARAFKQQGYAVFGTSRTVESAQELARQHPELFQATGATRNVFVFDGAHWDLTANGDVSVEQALAGTTHVIVSVPTGRVEGQEDPVLFALGEQLIQIVQPTLQWLAYLSTIGVYGETNGVAVDESAPVQSTVKRSQMRIAAEQQWLATGLPCHVFRIAGIYGPGRGTITKVRSGSATRIDLPGRLFNRIHVDDIVNILEASAAKPNPGAVYNVADDEPAPAEEVTAYACELLGVPAVPLQTWEEAEKTMSAMAKSFYAESKVVRNTRIKEELGVVLRYPTYREGLLAQLLEEEAQFDVSADAVADAAQGAEPLVVLANIGSLKPEPYLDLRQISFRLSRALRRPVVPCSFRFSNRIDPSLLHGMAAQTLEMVVTDYLQKKLAVRQDASLQVVILPLFFGNSTTLTEFLPSVLEKAWTKVVSPLSSVDAKLAAHVGRCLVDLEAPRDDRVAKILSEKVGLVLASEDRVKGDEHVTVLVLEHGTPNREVHDATAQVTRQLRALLPEDTIQRVGNACMERREGSQYDFNDPLLANAIDHYGITSGLVIIALLFFSQGRHAGEKGDIEEIVDDVKARYPHLDIRVTEPLGTHAFLSEILQDRYRQALQSPPTHVLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U8</accession>
    <name>A0A8K1C5U8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras-related protein Rab-23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U8"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001329">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="61517" checksum="DCE9DF9620CD5070" modified="2022-08-03" version="1">MDDFECDDFEKTLKVIVVGNGNVGKTSMTTRYAKGRYTGNYKKTIGVDFMEKRVELRDLGETINLMIWDTAGQEEFGALTSRYYKGAGAVIYVFSTVDRDSFEDLPKWQRKVEEECGRISQVLVQNKIDLVDDAAMSRGEVEDMADYMKIRLFRSCVQDNVNVKEVFEYLCRQHLRYGSHDGGAEDAVQAVTDISTLSEVSSRARAPPSPRSERKAQREISEISDDTRSVPSAPPSLVAKKPQRRHEEDEDSPRRGRPSRSDRKSDRYDEDDEEEEDEDRHGRRHSTRQRRDHREDRRGSNTERTRDRDRDDERDSDRGRSHGRDRERQRDREDGRERHDDRHHDRQHRHRDKERHRDRNEERRKERGQERHERRHTRKRDNSDEEDIQKRAKEPEEETSTRARSSKPSKQKTREREQAPEAEESRPVDVVAPRAVEEPDDDGADEKALSKATESVVATEEKEHESEHARDTKQNGGEDEDDDPSAPARPSTIGTESSSNSTRVQPSKRRTNGKKTHPIIHKMSSLLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5X6</accession>
    <name>A0A8K1C5X6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5X6"/>
    <dbReference type="OrthoDB" id="10649234at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="24720" checksum="B56DF94EDAAD7FFB" modified="2022-08-03" version="1">MTLQVDAAEASAPPTHVGGAQLQSISEEQTAQADTMTIAQVTTYSTSSTSMRMPSMRSSFGANPMMQATLPREAGDDPLASPVGFKPEPIDEDEPTPAPQVEEKPAPAPAPTTRSFLPSFARRRAAPAPAAPAPAAAADTAKQPPSLRRGTSAPLSASLLVSKVTPMLKRVVSGSVKTPAPPPAPTRAEHQDEDNIMDEQQHDLLLQMMQVPMKRRQSQVPLMSFGHEQPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C656</accession>
    <name>A0A8K1C656_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C656"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000002">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="201" mass="21703" checksum="CF52A37A46350259" modified="2022-08-03" version="1">MLMNVLKQRAPVMASKRMSFQAFRFSSDAKNPTVFFDVSIGGKASGRLVFELRKDVVPKTAENFRQLCTGEAGVGQSGKPLHYKGSKFHRIIPNFMCQGGDFTHGTGVGGESIYGRKFPDENFTLKHEGTGLLSMANAGPNTNGSQFFITTVDCPWLDGAHTVFGELTEGHDVLKAMEAQGTSSGATRSAVVIEDCGELTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6K0</accession>
    <name>A0A8K1C6K0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003304</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6K0"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF9">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="363"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="763"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW57379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="825" mass="91538" checksum="F6EAB0C0DCA5CF23" modified="2022-08-03" version="1">MTKSPATQTAANGDGRRLEYVVSDSALEVGESVASVAQETTEDVVEARTPPRMPLLERLRKRGRVESESYDHSPQQRSHAATVLSASRGAVGYGSPLRGLPAGGRRRVLLLARSLSLPNVHEETDDPAIHNIFPDVNPMDLRIAEVKSWDCPWMHQSFPVDAETSRPEPTTNGSATHKSPQKQQRANGQQHDARDELEAVIATISSEFSMEEKALTPAHSTAMMSPQPLSTPSSTASSTRLAKRPTLRLKLEDMPTPQQAEDRAQRAASRIIARREAMERAMADGQDTGDGASASQKAILRLNFKSYSSGDESDVQSPNGTGRLSGSSAYSPNQGMFTTKSVAVSEAGISSPDSGYMHLQEHLERVREIGRGASGVVYKAVHVPTLKVVAIKDVPVYGRGQRRQMVRELHALYSNLVPISDNDKRAQSETRRTSAAKAQASPYIVSFYDAFVDRAKNCICLVMEYMSAGSLQDIVLRGGCQNEKVLSRLAHGVLRGLAHIHSKNMVHRDIKPHNLLTNRQGEVKISDFGLAKTLNDNSSTTKTFVGTLLYMAPERIGGGDYSYAADVWSFGLALISVALGKYPLPTQDGFFGLVDSVANEQYLELPKDKFSSNCRHFIHMCLKTDPEERPPAQELLRHPFITMYTEDETLEAWNHFVDNTHLCEDREAELTSLGEAVYRHIYERSVKFSYQPQSDYGVSFASPAAPFARKEVSIQPVQMSLQLGLANYLGLPVHLVYELFEEKRNHYSDKLLEEYCYSPQSWSASPGIGRRQQWFGSDTESPMARTRERTGSSFWRKLHDGLSKFKNKRRQSKAEKGSSRHLGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6V9</accession>
    <name>A0A8K1C6V9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6V9"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="195"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="587" mass="63463" checksum="575B5A75AEF19B7C" modified="2022-08-03" version="1">MEQAASSDATSAATKMPSTNSRDRSISMNRTAETPPAKKHRASDDECEAVHDQKTPPPAPSIGASQKASSTDWQDSAAASTHSDGETKAGETTGDQSPSSVSSGSSGGSSSSSSSSSSSSPLRSNIPGLAGGLTEESFLTWLMDQKEQGISAGQMLDVLGLGVSEGVAVDDDELWDAILSMGIRLIQPSIPARQKLENVNTLQDVVDLLQRAQKIVVLAGAGISVSCGIPDFRSENGIYSRLGEYNLPNPQCMFDIDFFRTNPRPFFAFAKELFPKSNGFTFVPSRSHYFLKLLESKGKLLRIYSQNIDMLEHAAGISHERSILCHGSFATATCLACKKVYPGDAIRDEVMKQQVPMCNDCGSESGIVKPDIVFFGESLPRRFHDSIKADENEADLVLVMGSSLKVNPVRSLVGRIHKDAPMILINREPVGRPHRFDVELLGYSDDIVEELCRMLGWEIPQPDPVLLGQSNLSFNPRPLAKDRDPLPFELIPPSRHLFDGAKPDTPSSSEDEGAGDSPSSQDDDEEEMGSGRYSRDLDVGMDDPDARSANGMDDDAEEAEHLMGSGSELLRPSMLEEDMSAEDGDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7J7</accession>
    <name>A0A8K1C7J7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7J7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="209"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="29131" checksum="F3830DDFF3638937" modified="2022-08-03" version="1">MSVSMMPLAAALQPTRSSSSKRSSLSGIPSSSHSYVAPVSARHLEQMSIEIEASLKHVNDVRYVIRVHHKQSQMRWSLSRSFDEYRAFQTRVLDLLRQGHFCHAECPWIYSFVASYFPKSSMFRSASSRTVTKRREALEKCLQKLQSFVLTRENHSCSVAANVATELLNFVCGSLVDTAEFELCEKAHRDSASSILSSTDDESDIDAKCPLCDLGFTEESGPCCSYTTTLKCGHEFHEECILSKLNESMHCPVCGHSELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9E5</accession>
    <name>A0A8K1C9E5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9E5"/>
    <dbReference type="OrthoDB" id="118115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="28831" checksum="C74E74C2C570A786" modified="2022-08-03" version="1">MGGDGISRRLRAAIHAHSGFLLGAPLPATSPASAAALYYAFSPSGGVLAAKVFTDYATAFDHEVAVNLQLEIGYSVVKFISSFSVIEHGDDDGSISKLGIIIMPFFPQNAADFLQYQSPMCLNTITVIARDCIRALHHLHSKNYCYGDMKPTNIMLQGGEQGRAMLVDFGATVALGAPLLEATARYCLDIDVSVGTEMVDWVCLGSTLAELSGFDLGAYCTTKSLIHDVEEAPTMDTTLQEMIVSLLRGHIVDKPVLSALLERAGSFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9I9</accession>
    <name>A0A8K1C9I9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the free Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9I9"/>
    <dbReference type="OrthoDB" id="15735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033745">
        <property type="term" value="F:L-methionine-(R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000008">
        <property type="entry name" value="GAF domain-containing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF15">
        <property type="entry name" value="FREE METHIONINE-R-SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="133"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="33110" checksum="BEB26986B4666039" modified="2022-08-03" version="1">MADFAQVVALFASVEEPQRVENVVLEEKTKPVVVLLYRKDREYKTKPFLNALAFLFRERSDLALYQSIVKDAEPSLTVYKNGEKTVSVNPKSGSAKDQILALIEQIGYSPDCPDEASLPRYFNPVDYKEVFADIEAYTTSQRDYVSNTANVSAIIWHAFQEAKRPINWAGFYFTRPLAKPKEDETHILILGPFQGKKACHTIHFDAGVCGAAARTKTVQRIADVHHFEGHIACDSASESEIVVPVFNDQGEVIAVLDIDCPEKAGFTKEDERQLVEVCKIVAAGSDWHNMSLPFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA85</accession>
    <name>A0A8K1CA85_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA85"/>
    <dbReference type="OrthoDB" id="46836at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343:SF17">
        <property type="entry name" value="CELLULAR REPRESSOR OF E1A-STIMULATED GENES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343">
        <property type="entry name" value="CREG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442755" description="CREG-like beta-barrel domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="44"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="212" mass="23282" checksum="193E5C4EF37D9AF5" modified="2022-08-03" version="1">MTGLRGSVTLLLTLMLSALLAPSMARLSFSWTLHVERVWEAPSAGTAAVHARQLVAKNIWATLSTLSVEFGGMPFGHIVSYSDGVGSDLKNSTGHLYFYLTKLDDAGKNLAADARASVSISMAQEGEHACKMDVEDPTCWKLTLLGKVVRVPADKQQIALDALFSKHPQMASWPSDHGFHAYMLDIEHLILLDFYGGAKSIKPEEYYRVELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB63</accession>
    <name>A0A8K1CB63_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB63"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="20533" checksum="64DA1DA396912B18" modified="2022-08-03" version="1">MSRRCTTQSVATEKWQNNYLVAEGGKCTENQTCSSMGGGTSNGYRVGCCMSGAASMNAYTKATFGTGVNTVTWVIFSDTVCKNYVVASDSQMTTSLDTARCNPQTDGTTKTFTYNATALAVTSSQFASKDCSGNPINSTIQQSDFGKCITLGSISLQAYSTIDSKTYGLPADSGATVTLGLASIAVSLVASYFAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCI4</accession>
    <name>A0A8K1CCI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCI4"/>
    <dbReference type="OrthoDB" id="67196at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="START" evidence="7">
        <location>
            <begin position="142"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="262"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="68130" checksum="EB8117D3C813CD5D" modified="2022-08-03" version="1">MLSATETTTVEEMSPREKERLTSVAKSMTESLLETTDLLGGVPWFLVHEKAGISLFRADVGNDVPCNVHAVCKFNSDIEDVANSMITTTTDSYKNMMSMLSSDFIDGAIVENIVEPTEANPYRYVALKWAAYKSSRSFGKDRDFVLLEYVDMIEDDQGQKIAFRIMESVDVPNNSPYAESSRYTRDIVPLVGYMYHTTKKAGELRLTYTCNFDKNGDLPAWAANSAIQSHVEKCINGLLKYIESYRTSQEEIVLPQQQVIPVSEQDHCRLCTKNFCLVRRKHNCLKCGEVICSNCSRLRTAIVPDVGERQLRVCTACALAVRRSSRSPLDGTLPLTANGGDEKAQAAVGRTQSYSTDRRQRRVVDDLLDPVRSRLIEYKNFADAPDAGVIPKANFPGRSFSDGLIMRKGSLFGNKRRGSPADLAISIEAFRQHQLRMGNSEQQPEDGDQSDEEAMNQLRYFSSSLTSSSTNSSASSHPTVDEVLAPLQAMQPDIEHGPSRKQHQVRQVEYESSHSIESRARLNAAMELASGIIEQAKYANSLAQHARRVSHHRVLAIQREEVFMSVRNDNSDDDGRQAPETDNHSRRVVYQVNNGAMLYGKLDRDPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCK2</accession>
    <name>A0A8K1CCK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000936</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCK2"/>
    <dbReference type="OrthoDB" id="421393at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="287"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR009449-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="475" mass="54620" checksum="8E6087E6ACDAFFE2" modified="2022-08-03" version="1">MLNVGNRRGEIQEQRSLSAVTLSMYNEPPLVEVSLEEFEEYAIDRLHVLKAVENYRLRSTTAAKDKESRLDKVINKHMPLRAGGPSLSRRAENDSVKDVLSHFFLRMAFCQTEELRRWFLSQESVLFRYRLDKMTREEKIFFMKQNGISYEEATPKEVEARQSQLKAVRDGQLLDRKQRSNPLPAFFKVPFTDALDLVGTRKVYLEGGIAYVPFDHVVSLLYATFRANLSKQLAAAFRKYNRSLIGKDERLAPVLTNLAKHHIDADYSAQFQGPGNSDNRMTPEMLDQMSSTSMPLCMRTLHKALKVNSHLKFAGRQQLGLFIKATGLQLDDAIAYWRQAFCKKMSVDDFNKKYAYNIRHNYGKEGKRKDYVPYNCMRIITGEPPKAGEYHGCPFRHYEEDHLRKALQGVSEPEKQDIISLVQGKHFQVACKRHFEATHPGCDPDVMISHPNGFFEESRKYYAAKNEGVNVQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCT8</accession>
    <name>A0A8K1CCT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCT8"/>
    <dbReference type="OrthoDB" id="271910at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160147">
        <property type="term" value="F:tRNA pseudouridine(38-40) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="176"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="39425" checksum="E74576D7CAB5B976" modified="2022-08-03" version="1">MSCSDGSDQDERLSDVEAEQNAPRWRYVLHIAYYGTGLVGWQRQVEKSRSGQGSVQELMEDAVTNALGAAKRINVTSASRTDAGTHALYQYATIKVDQELTVSLADLQRDLNERLPEQVRVLGLQPLPASVKPSRFRSKYKKYIYYLQQGYRPDLELGKYSWFLGKRIDVMRLQEAISLLVGTHDFRPFSQGLQKAEFADRSTVRTIVSAKVRVRRNVIFSLDPETCGNGDIIEDVNSLYDACAATEYDEPEAKKRKLDANAKEPARPMVPVHFICVELIATGFLRHMVRRIMGSVRPIAEGTYPVSRMQQILDGELEPGPSAPTKGLWLHRTWLTQEDWDNDTIKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCW9</accession>
    <name>A0A8K1CCW9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCW9"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF102">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE JMJ31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="117"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="46243" checksum="270F6ADEED41CEFB" modified="2022-08-03" version="1">MIASTEPTFLKGFARECVHNDQDLALFEPGSIHTLAAFQSHRDTVVDVACKDKSGRFYSGDHRARQSVEVKFGDFLDYYQATNKGEPHWLGSVEDLEFYLCQCPIAVFKPDDTSSVATLPNIMQMFKVPNALAGANLTQTNLWIAVNSSRTSVHYDAYRNVLVVLHGTKTVTLYPPSDTGNLYSRPIFSKSSNHSEVNFAHPDLSQHPAFANAHPQVFKLEAGDALYIPEGWWHQVDTSAYCIAINYWFDGLRAELVQDPHMTTYYARVAMEELVRLESSRILRQFHEQAAHTVNSATPSRIVQPQSQTEHERMLMSLSEQQLKDAQVTLASSHPDDWRALLENASVDFAAYLADHWDRQTDQLDWLSAVLQALGEHEDRIKQHLLEQQEAFQHKIFKQVVEAALGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDM7</accession>
    <name>A0A8K1CDM7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDM7"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="336" mass="38467" checksum="5116FE22F5051AA0" modified="2022-08-03" version="1">MACGWTPDLMRMLEQMAAEKEKLATQSASELHSTTKHIEKLRQKTEVMPTDKTTSDGQYDWTSVYEKWDAWEDPEELAQREQEAREKHERALKSQQQSMCNHDHSAEQKLMDMTTDAKLCACDEFRVLGNLFFAQGQYQRAAYNYHKALVYFEYIFPEGDDENKQHDQLKLTTLLNYCACRLKTGHNDDAIHHADLALELDPHNMKAFYRRAQAHRHRDDFDEALHDITEALRLCDDDQKADTAALLHEKALLHAKMLAYKLKSRQISTAMFAGGIHSTEKKKPTPSAFAPVHDVPLTLSKASMSERRGPKAIVNFESGEPCTDGLVELQQLVESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDW4</accession>
    <name>A0A8K1CDW4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDW4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="367" mass="40824" checksum="2AD349180281F027" modified="2022-08-03" version="1">MFAIFLLDRTPSISCSQSSDGHRVGSAWSKDSTTDRVLALIAAVATGLGILMAFVPSCYFANPLPFTLVLTSPPWLAVLGGGLVFYLRHEIRSNPAAKKDLRQYWTIILTQLHLPLVYPLYHFLFSSLSGTCTKAAFVPVLSVIKLAFKNVMNRALYGLDDLKPQTIILNVEAFHALFATYSMQNSSSSLTAMALVALDFFHACVSFYDVNELLAQVTTLVDSLRTTKATTDMSVLEIALFVINEETEDVEPEDTANVITSLMPTVKHLTQVAPLPQIETPARASARQQRASTDYTRAPSVQGPPVHQERRLLLHKTLQLLYLTEFILLIEFVEIIIPPSTVLIYLNAMFHLPNRAYYPAIKDMDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE89</accession>
    <name>A0A8K1CE89_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE89"/>
    <dbReference type="OrthoDB" id="97518at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="29397" checksum="80C5FEB9F6627826" modified="2022-08-03" version="1">MGGTQSFTALVPQLHCPPAISGRFCRRRDVTLRLHPRMWTPTQPNEIRDMHSNLIMFCVVPRSSRHLHTAAIQFQLVDPYKMPIATLERTHDTSYDAVVYPVTAVDASADEFGHHETRHVGVITPHTSQCVQWTDPVTQESFVCTYEGDWGSHNGCFWLQRGFESPRERVARVYRPDATSGHAFNQDYHLDVAAGVDIALLLLICAAFDDTTHTRREEDERAAAEIASHRHWRGVDRDMLTPFSPRQSQAERCQVPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEJ8</accession>
    <name>A0A8K1CEJ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009479</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEJ8"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210:SF1">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="344"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="482"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="267"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="582"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="679"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="760" mass="83654" checksum="8F7C0B8EF35E3F89" modified="2022-08-03" version="1">MLRAKAAMGFKSVPRVEVKAETTTPGEVRTTTDANGMRVSTSRARRTLPKLEFVIEENGAILHGPQRGLFPYYSTSQYYHTETGSSTALIASETQMRNVASTSFSSLHLRDFGAIPTSAVPAPSSNQEEAAASTEADVGEDESEDVVDRGSFRKMSAPSAHSTTPMKDCVLNDTRATTLAVKYDNSVGKFVCGSSIERFSGHTGVCRVLGSKKYPIIPHSLQIGDLLRIGSVGLVVCEINRGPAEENLESLTEEEYQYIKENFLSVPLQQTFRPTDPRNNNDGEHDDDDGEDDEESRQNKLRAGETSDEGESEEDGHKRASEDSEDGECFGGGARSKAHRLKDGLGGEKRFCYICYDGEEEPDENPLVAPCNCKGDTKYVHLECLQRWNNNLDADGTNPNQKMCAVTNTDGLDVCSICKATYLTSVKLEDGRVVSLMAKKLPPPYVTFAVVTQHETRSRSTTLTNTRFQLSFANMPRGQPYLTIGRSTTNNMTLRYRTVSQLHAKLKFEDNNFYLYDAQSSNGTMLFLSRPLELEWNKTMHVKIGRTILTLKSKKRWKWSGGGEVDEDPNAAIASPQSAHALLTPPTDELNNQTQETTTATPRPPTGNRFEVSAASLLSDPSAELLTSPFAVALRQPLNRTFTSTLPFPSHQFNRPFAPPADIDPDLDGLRLSDIVDEGSIGSGGSRGSFTQAGFAGTPRRSLVSTPSNRDSSENPRGLSRHLEQRDRPGYDYVERLSHVSIGSPQYVDRLSALDRLDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF28</accession>
    <name>A0A8K1CF28_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF28"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049916">
        <property type="entry name" value="WDR72-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099:SF4">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="486"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1213" mass="133496" checksum="3CF9DC9DD5D4D6DE" modified="2022-08-03" version="1">MSWTATNAYSPTVTKKPSMATTTASNSTATGTASEGSVFSERAIDQARDDVVVPLVLWNEPPRMDITSLHVLYLPMSQPSQNTSALMNRWPSLASFVQQYSSNNLNANATGSSFASLNSSHSMLNLKRVLSQHRSKRNSLSVEDRAALATAISNLANGAGADLMDDDEFQYVDDGDFDTDDELYQLCVFAGTADGAIVFWLFEQDIVVQVNVLVHPSVSEGYRDELLTGNSTRQISPVQSVVSGIDEWGQSNLISVTRDGAVARWELPNGVCARADVTLAAQLAPVKGMEMFCNNRYAIVYGEQSRMMVLDTWKMTMIYCVDTAQEQNPFHRARFPPTVQKRTSGSRYLNIHASTVSPHPPPAPLKPSLAASVTDPAANFVVFTGGVDGSLKVLELSLQFDGESFVVDATVLQSFKQHRGAIKEIVISPMMRENSPYPERYVATIGEDNTVNVYAPIYLQNPFAHGPARTPSRSRCNIEWECVMAFCEHPDTICGIEWVTDRGVLMVECEDRQVYVWNLDTGVLERSIPTSLVYEGGNLSIDGRQEGESESDIASVECTNLGIGDSSLHLLKFNVNKSAELIKANWKTYYFGLVRGKSRFSADQEGGSSSTSKRATSPYAVGSIELVLLSFLLSWGAAPEIDRACRDLLGLETPHSLYSCVLMDQISGAITIPVPWKSIFSPMSPNPAEANPFPRKWQHSSALSANVALGIVSLCMNLMEHKYSKSEPSESFNGAHLITPSSPRNKEEFHVLWSQLITQHSVVLPDYVPFFREPSLEFLAKYGFHTSDYTQLAARALLSGIIKRLAPLSRSALCAEYSTKLHCEIMRLETETGAKLNSSSTSLPIDPVLVVSRLGSLVILLSMVGTCFPGEISPAGAREVCDILVYLLRAPAQYIASVAAELLTKGLMLFRPHLVDLSSLICQLLIIDMREKQRNPGDDSPTFGSNARVLASGGSNAALSLLVELGACETAFVLNLLQQEMNNADRPHAFRECILLYLTELINTHYLLMFRHLSAVVDTIMCCLDPTKPERRKRCLELSTICLHNIVRRFPMVDFHKDTQRLALGTMEAVILIYDLRTATKWRVLDGHTSAVSALSFRTDGQILVSYAAREGSVRFWNSGNAGIFGGMLKMQQSCIKEHKLEVLRGFAHAPASSGGASADLKQVIQTCRFQFLVLKDAPNGNQQAPTNGSSETNERRVLRLTREDASQVQFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG87</accession>
    <name>A0A8K1CG87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WLM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG87"/>
    <dbReference type="OrthoDB" id="261960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="298" mass="33272" checksum="A14730AD3C69D5C5" modified="2022-08-03" version="1">MTSMTSFAIGEIRALVRRADRSAAQTVLEKIADAVLPIMTKRRFRVRTLREFFPKNPHLLGMNVNRGATIYIRLRPQSLPDTFLPYEALLETMLHELTHMVHGPHNSAFYKLLDELKDEMESLMVRGLVGQEGARFYDAGVGHSIQTEVSHIPVRHTNDNHAAVLAAKRREHYQRLLGGVTSQRLGSAGSMTSTSRTLAPRELRLRALEAAERRRRDNTECGNVVIAGTTSTPETIELLGLDDTDDGENEMEQTPVGRPLHSSTPAVVINLVDEEDEIVPIFIESSNQVIDLTIDSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGH0</accession>
    <name>A0A8K1CGH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGH0"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="14"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="35154" checksum="1B3A1D782D094E08" modified="2022-08-03" version="1">MPTTQTRTVNAYAATKPGLEVEPFQYQARPLGVEDVEGAISHCGICGSDLHTISGGWGGANYPIVPGHEIIGTITAAGPDVKHLKDTCKECASDNESYCNECVFTYNGKYADGQPSYGGYAEYVRVPAHYAFKVPDVIPSDVAGPLLCAGVTVYKPLRDHVKPGQRVGVVGIGGLGHFGLQFIRALGAEPIAFSQSPNKEQAAREPGARSVDTLLVTADAKGQPYDTYLGLITIGGKLIMVSIPDDKMAFNAFSLVSSGISVVGSLIGGIKDTKDMLEFAAKENVRPVIQKLPMKEANQGVKMVDEGRVRYRVVLENKATPKRRRRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGL1</accession>
    <name>A0A8K1CGL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGL1"/>
    <dbReference type="OrthoDB" id="10249775at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042507">
        <property type="entry name" value="TBC1D19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110:SF1">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="307"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="585" mass="65595" checksum="1C5F507B24A80F89" modified="2022-08-03" version="1">MEKNHAHVLQLYGPEVPIEDRVRFLTRQLLELDQVRAWKGVVKQELAKPENSLDQLLLLTQSSSRASEGNNAAVGALYRLVDKMGLVSALRRLILDLHYDATQAVHAAATQQSKEKEASFLPHADGGSLDVVQTARESWERITREELLRFASEQGKTLLSSLTNPIRNGTPTSATTTSETIEGDMELNLPNDAAPVRSYKPPTTTRFLYDGRDLLHTLQSIKPSNRSAEAVAAALDAWGSIQLHFHAPSSSALRRQYAELTPSLGQIGLDELFPSERQAFLAEKNRVGDLVLSHHSVSMARQYAKTGCPASLRAQVWSLALGQTVKSPDARVYFEQLQDQVTQWTYLTDDMYLLDLQRAIDSCDYFVFQDHLDSVVMAFTRDPHVHQHALQVNGTVHLTPEQHQVTQTAALPPPNKCVPPNGVLPFSGLVMYVAPLTYLYTDPVQLYYVFREMYIRYWSRLNAIRSDHATILPLCRLFEDLVVRSSSAAVFHLLNVGVQPLDVAFPWIQGAFSGVLELQQLLLLWDRIVGYDSIQLLAVVAAALFHFRADELEGVTSMDEIRALYAEQLEIQVIPLLQEYLFLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGR8</accession>
    <name>A0A8K1CGR8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGR8"/>
    <dbReference type="OrthoDB" id="61413at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="266" mass="29498" checksum="860856DA5EEAE21D" modified="2022-08-03" version="1">MQHSGTTTFLMGGEQREFRFAVEVTANEELSIWLEDKKTRAQWQAIGLTTTSFIAPETTIPGATLVDYAKGFAECLRAPHAAEDGSMGRLLSDPSKEGTRTLTVTLPFTWFSVAKTLTYEFTLIAMALDPVQVLTARVCELEEALAATKPNPPVQLDQIEGRELTDDEYLCWDVTQSYTHIEASKEAIRITQDGIYAVQFIADYADDDGNDSFVSTLEINGKAVCECEGYLDTASGLWFLKTNDRIRVKFDDDVDIVGKLTIVKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH14</accession>
    <name>A0A8K1CH14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH14"/>
    <dbReference type="OrthoDB" id="10266771at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="2">
        <location>
            <begin position="71"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="22920" checksum="74206DDFD67830EF" modified="2022-08-03" version="1">MTLAEVLYAYDLTGAQLLHQRFGQSKLARALWEVLSHTGDGILWFLMVLPVVGIMWLAGYLDNASPAAKTVFVSFYTCNFVDIIAIILMKLAFKRQRPPHHRADGRFVGPDQHSFPSGHATRVWCIVALFLDMSSRQPEVIRSFFSISPTAMRVLIVLWALSISFSRIALGRHYPSDVLAGSLIGAFLLYPIASLIIQQTSGVKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHB3</accession>
    <name>A0A8K1CHB3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002323</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHB3"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000018">
        <property type="entry name" value="S-adenosylmethionine mitochondrial carrier protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="98"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="189"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="282" mass="29992" checksum="3542C2D61C295C4C" modified="2022-08-03" version="1">MTDADVRNGVEAKSKGFLASLLGGAVAGTSVDIALFPLDTIKTRLQSAEGFFKAGGFRGVYSGLSAAAAGSAPGGAMFFSAYETSKKAIAATFPEHKQSPFAHMGAAAVGEMSACLVRVPTEIVKQRMQTGVYSSLQGAIVGIRTTEGVFGFYRGYWSMIAREIPFSFIQFPLWEGLKNQWSKQQNAPVSSLQGAICGSIAGGCAASITTPLDVVKTRLMLGKDAKGVPYTGTVDTFTRVYREEGVKRLFSGVGPRTMWISIGGFVFFGMYEKATETFSTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIN7</accession>
    <name>A0A8K1CIN7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIN7"/>
    <dbReference type="OrthoDB" id="69209at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="39423" checksum="79A34FB713345144" modified="2022-08-03" version="1">MPDMTVGMTAQVATFVRILNATQTSELLEWNLESLERALMWARAMETLASQSKASQSGDRVNELLTEQLPKATVPSMEASDAVLSVQVLEQATTHLCHSILTSPWLGAHSARSEFASHVIKHRLQHGDLVKCRRASRSLSATFTRQHQTEQRVEALSQIAERMSRGCKRVRVNVLSGWLEIPTRGSFLLVPRTLQLRALAKSLRANAAAARAQGPNHYEDFLQTLYEHLQQGDADVQETLAWMVVLDLNESTSLAIDSLAHKILALLEAQVTTHPQEGLYGVSAWLAAKLCALSASLQQQYVSTLVSTGLLRLDPEDFQTRIGALVLESHELQAIISHELRKLEPPVLKEHFHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIX5</accession>
    <name>A0A8K1CIX5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIX5"/>
    <dbReference type="OrthoDB" id="164262at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00042">
        <property type="entry name" value="CY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000010">
        <property type="entry name" value="Cystatin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018073">
        <property type="entry name" value="Prot_inh_cystat_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="Cystatin/monellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00287">
        <property type="entry name" value="CYSTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461682" evidence="2">
        <location>
            <begin position="22"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="20452" checksum="559EB56192349189" modified="2022-08-03" version="1">MIRQLVLSACVLGAFATSSMAQNTTAGGLSPHTVGANETSLLETALSSETGYQASVTQRLCYTKIASLETQVVSGMMYYFHVDACELPKGSKLTGKCDASCEAKRYTVKVYEQSWTNTVQVADVQEGDVEAATSGSTESDGHLLLGHTQSGNSSSGDMEPSTNASTVPSPTPDAASRLFQQGIALGVVVVSLVVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ47</accession>
    <name>A0A8K1CJ47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014699</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ47"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="598" mass="64833" checksum="D2C4ECA2CDEDD688" modified="2022-08-03" version="1">MDHQQESQTRGSIDRSIHGGIVLLDPQHQENLSRRQPRNIHSFISANEESTTSSVVSAPNSNPRPTMEPSPYGRVTMGSPRTNFKSSNQTDAPPIAEHLHALEDSPIESVDAIEGDARAIHAVTTMQISFTWIMVGIIAGIILGSVLYFLKVSPLLAQWISLPGELFLRALKCLVIPYIFFAVAVAIGDIVYVGKVSIVGAQTIRVFLITWIATAAMGMGVAMLFKSFFNVQEAPPVSKHPIAFTCKNGETFELLSNGSVACSGSAGNLSVDALFEPVDVNSFFKKASTASSLTTLSDIIRASLESFVSANIAGSFTSSYIPGIVTFAMLLGTIAGHNFFNKTRRVNYLYLVMLQMRNAFFLALEWVIWLTPVAVVFIVAGSFAKNQESLAQFSRTYMFVIAIFVAAVLQVIVVKPLIVLILTRCNPYKHMVPMIRAYLFAFGCSSSLNTAPVTLSCIRKAKVCSPSIANFVISLGVCANSSASAFYYPITVVFLAESSDMGSELTPLRLVGLFVLGMLGCVATPGIPNGALIALEPIYKIVLGVSTMPSTYAFVIAIDMFVDRIRTVCNVNDDIMALKVIAENTDETVSAEYLGQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJD7</accession>
    <name>A0A8K1CJD7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJD7"/>
    <dbReference type="OrthoDB" id="159280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463309" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="32"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="158" mass="16985" checksum="1336FAA70D0147C0" modified="2022-08-03" version="1">MKLLTSLWTPLIVFTASLGAMAQQDGVTWELLDIINTLRAADVEPLLCFNAKLTAASQQLANEMALTGVLSTTTLDGSSPTERAVAQGLNTTGVSELVGAGYENASHAVAEWLRTPAYRAYFLSNDMFVGIGYAYNAAQTYKSFWVVDFANATNETCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJE3</accession>
    <name>A0A8K1CJE3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJE3"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="228" mass="24483" checksum="98A05BA0C19EDCB3" modified="2022-08-03" version="1">MSFKTVMITGCDQGIGKALVQYYTKLKWNVIGTTRDPEEAEALREANARIVAMDVSDEVSILNVAAHLAGERIDVLINNAGIMIRGGLQNISKKDLMDQLEVNAVGAFLVIQGFLPHLRSAVDKNGSALVINIGSRMGSISENTSGGLYGYRASKAALHMLSVSLAVDLKHEHVAVVVVHPGKVETEMVAPGELTPVESASMIAKLIDTVTMEDTGKFFHANGTQLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK01</accession>
    <name>A0A8K1CK01_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK01"/>
    <dbReference type="OrthoDB" id="548799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="39130" checksum="ECF5B14B56E5637B" modified="2022-08-03" version="1">MDGGRRSISEELRDDESQPQPSRRADVYERLYDRRSYTGVYRKRFELEIHDLTDTVVHDLSSTIRPNLNYSVTPKQQKRAVSPRLSISSSTPASITIEPPPPSPSPEKPPCPSPIQLKGDPNDPHTLLKAVFHYYCRFGRTGAKGVNEKTMNNVNFSKLCRECPDLLSADFTTTDVDLIFVKAKKKGERRINYTQFLDALGMLALEKYPETPLEKSLPKVLQVHLARLPPIVELTDGRMRNAVWQRRRSSGSRPPSPRTPQRRASVTQTSPPRVHFPHPTPSHSPLRRRQSAPSSVMSNSGLARQFINGLPKLRSFTSFDTDALASPTPTSFDDLPYTEESITEVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKN5</accession>
    <name>A0A8K1CKN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKN5"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="770"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="426"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="942" mass="102726" checksum="9DA76532FE88A4A5" modified="2022-08-03" version="1">MPPLRSGTRSCGATTATVDPTDAKRALVQYDNCTKEVVKLEDLPDARRVLDLKHRGIQRVESIPEATELLDISWNPRVTADLSTHEGLTSVYARGCELTDLSQIKLPSRLQELNLRTNNFTRLAAESLPVALQKLKISQNEMKSLDELASLSSLQVLLASENQIEAIHKLSPAIQVLDLSYNKLSALEDVRLPPKLTQWNVSFNSISAIHGVQFPSTLEKFDVRSNPIAEFRVNKGDFELFRNDSVVLATPSEWKPSASKCPDVEWIGTMPLCVVVDSGQSAAEYSAATVTPIADHNGTSGSANADANVTGGYSHDAGRLALFGGIMVGLCALVLTFLLFTYRRRQKRGQLTIAQFANSGMKKAPPLTTENRTSKSTFMSSTSPDPSELSNSMAPIALTPISTDATPGSIWVDSNLSSMVLPAKSWYKDRVFAFGDYGEIFVAKSRAATRGSKFFLVKQIHPLAALTTHGVEQFVEEVQLCSKLRHRHLVPFVGVTGGDASTSLGYACDYISDGDLQTALARQRSRVDHHKTFQWFSSTSSEIKTRKLDLARELVHALEYLHSLDTPVVYQSLTSKHVLLVRAQNIQLSLFGICQTVALHDMLTKSGTGGSNVPWIAPEILKGGKCDVTANVYSLGVILSELDTCQPPYRSGSGDILPPNASSARIAIMVSAGIVQPELRDDCPRAISELIQCCLRFEPESRPALSVVREALDKLAINHDAAVSDAKQTCLTRSATRGIVVPAESTRQAQHLKQTTQTDARGVWGKTLSAYNWALWALVTVLLFAEVLGIFVSTVTTSTILVFGKKPAEGLHNIDGQNDDPFTDRSIACIRQGRLFHQVPLSVALASTSTVTISTNATADNFIHGYRVVERKEMAMEAAIEAFYTKTCGLLALTLDQILSACTALGYNVVDDSLRIVPGIESNTMKLLPESLPLLIVPFWDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLG0</accession>
    <name>A0A8K1CLG0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLG0"/>
    <dbReference type="OrthoDB" id="157835at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="655"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="838" mass="93665" checksum="2EC5FD1306CCC892" modified="2022-08-03" version="1">MSTAASEVGAPWVWVTPDWAAHPVIENYYGHARRPRDNSFYDIMRSPTNTQPTRTLAEACNSYDKTDEEEDTVLGVESAQQMEGTHTFFRRSSVTERNDRLRQTGRGAVAVTATTRKLGSFSYSYTTETSEDIATASPYSTSTRGSGDFGALRHMRDDSGEAEEVPSAPPLSATERYATWNRQRQEQDATTDMVPIPNANGLRKKPIANDVVGLTLQAENPQGGVSILEDASSTYSSRRSSMSSMADSPLSRKPSTTGRLRTKLQDSLMQIDERIDFEVRLAREAYANMKNTRPPSARESLVWSLLCGARTASAASQSDGLEMLHEKLSITLHNRALNQLQRHRRHVRGILQIVTSHNPDLYLTEKQLDSFESADAMLANDIKYSTLQRQVEALKTSLVKRKDALRHARIKNGRECFESQRVKNAMLAKLLEAVSWYRLVQTNSREESASTSVGLSVEAASAGDITHAPGDSGEELSHGPPSSKSSSSILSVSRSLQELQVERILNVLAGEDFYSDYSDLMCQPDWWEIAQAHFENLIFSRADSRLCQWLNRISKDVAGVSHEAIEEDTFGLEEKQKGSSGTKGSAQLFDTIPDWAKDPQPEQIIDFVDRFTRRVRKEFDVPCDVSKSLQSFVQRTVYPRLALLCFNQKSTIDCQRRDKLWRKRCTELSGVPMENLTVSSDLAGKIRANLPNRRVPGGRAYFIRAIDAFNCMTSLVPCDLLDELMYGVIILHHEAALVLGTTQFSVETFFPLLAYVLLHCQLPTIHAQLHLLENFAITNSNVNGEESYYVYCVHAAIEYVCNSAGLNTIEKKPKDESTAADVEAEPLEQKREALVTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLM8</accession>
    <name>A0A8K1CLM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal RNA-processing protein 7 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLM8"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
        <location>
            <begin position="136"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="27784" checksum="C3871A0B00EB7DD4" modified="2022-08-03" version="1">MASGLVGGYHAIALPLAHGVFKRHIYVKKHNTKESEKGGESKLAADRTVYVVNLPNNSDEDWLQQCLSAVGSIQHIIPGSEPDQNADPLLAKTAHVVFKSKKAAEEVLRVQTLDCPAPAETTGLNAYLEDYQAKKPGLVAVKELADRFMAEFDAAEEEEIREREDLKNQVDDDGFITVVSNKRKKAPIPEELMPVKKPKSKELQNFYRFQMREKKRDQLKTLRERFEEDKLLVEKLKKANKFKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMG2</accession>
    <name>A0A8K1CMG2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMG2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="127" mass="14722" checksum="1C5D37C3FF95B85F" modified="2022-08-03" version="1">MKQALHLTHEEYAFTTIALIAVLTSLTVEAVCTTLAFVYRFPLPFRELIGLPVWSTSVVVYNYIFAKSTLYRYRRKLKLYLPIVGVQIVFLYVFLAFSVGFGYLKTVTQIIVILIFPFIKMYLKHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMM5</accession>
    <name>A0A8K1CMM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003649</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMM5"/>
    <dbReference type="OrthoDB" id="167134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="402" mass="46486" checksum="70A9289A3415B453" modified="2022-08-03" version="1">MVRRDLEKDKIKEKKPGLIHFDADLLKLYLAREGDTWLNSRDAEIKALEKGEIPDRIKSLMQEELQMLETRNLNNDAYFSKTFERAENDIHVLVELPSAFGVPSVQQTGLWLVRGSIANALSTKGIRAKLYRLAGMFLGYYDPARYTGDSHSALWYEGKTLCIHVLFKTEENALQFENAMQDEPVTLGSALNGHEVTTNVTRINHVPAAELQRIFFIHYEPLESESPQDTMSSISSSSVTVLDSSTDEFRYQRIEHERYFLPYGKAERCHLVSAKQRKHDEAFEQYDHDMNNRLALSREMHGFYDGLSYEVPIMNIYPGKVDDKRSIANRYKVEIFVKVLDKQCKDRVFSRLKEGSDQTDDPLVMKTFVHVESPETFCFCLRWKHEDNDARWRSFLSNGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMS4</accession>
    <name>A0A8K1CMS4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMS4"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="2">
        <location>
            <begin position="435"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="3">
        <location>
            <begin position="558"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="675" mass="76419" checksum="30C7ED7DF9F74ABE" modified="2022-08-03" version="1">MGVFPLLIPSVEVNMASDEDVEWEDFADETEREAATGGDEEEDEEFVYSPGEEDDEEVDWEAVEGDDKSVSNATADKCLDSNSDEEDDEASAEAAVKDLNAVNWDHINNVLQREAEKANKKPKKRKVVRMSKDDKQHEVALHKSHLLVSLAMQQQWNRLCQVSVLRGLMLSLTSESDVDFYRDLDTMPRKYALELLVRWFNGVFRTRDVSRAGEDDAEDENEHMVTALLTESRLMRVFYSRRGHDYELAVLFTLLCRAVGLRTRHCAALDPLVVQQHTMAFESSAVASTPTSRKRARCSAGARKAEEPMETSSGQQFWAWSEVLDEKNQSWVMVDAVRKVVDRPQEIQTARGKSRPLSYVVSINAEGILTDVSSRYVDRWSKTLPLRLADDWFTHSLSLVNASIDDKCVWRDPEARAVELRLQDKERDELTSLKQSEEMPNSLEGFKKHHVYCLERHLGRYECIYPRKAVGIFKGQAVYPRKSVQTVRTMFQWRQLGREIKAEEQQKPAKREGKPSKGGGDSDDDGISPGGSGAVGRALYGFWQTDEVTVAAVENGVVPKNKYGNIEVWSPAHLPRGSVHLRLSRIERVASQLGVDFAPAVVGFEVKNGKNYPKIEGIVVAATVEAMLVDAHAHIQQSTIEQAIEKNQQAILKRWERLVKRLLLKQRLNDEYGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNH7</accession>
    <name>A0A8K1CNH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNH7"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF12">
        <property type="entry name" value="ENOYL-COA ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14303" checksum="3510787DD40521B2" modified="2022-08-03" version="1">MRVGIVPEFAASYTFPRTLGRQLTNEMLMLSRRIDAKRALAHGLVSQVFPVEDFLTKVFEDLAPMLNTPTTAKNLPTYKRLLRREDEARVRDAIQHEYAEFDRLFLTGTPQEATAAFLASLKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNI6</accession>
    <name>A0A8K1CNI6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008294</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNI6"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15848">
        <property type="entry name" value="SNARE_syntaxin1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000008">
        <property type="entry name" value="Syntaxin 132"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SNARE"/>
    </dbReference>
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        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
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        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="181"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="275" mass="31292" checksum="20ABE16E48465367" modified="2022-08-03" version="1">MDNTRHGVVRPKFMEEFFKDVEDMQMDLTNINLGTQKISELNQRAVLATSNAEEHAISNELTLVIEASNKLATHAKGLLEALKKESVERKKDKDTPVSEIRIRDNMCATLTKKFMDNMKDYQKAQQKYKNDMKNKVKRQVQIVKPDASEEEIDAVMRSPDPGSIYKTAILQGAADSIRDVYLNVQDKYQDVLRLEQSVAELHQMFLDLALLVEQQGEMLDQIEFQVRTAANYVEQGNQEVVKALKSQKSARKKKCCLLFVGLAIILIIVLVAAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNJ2</accession>
    <name>A0A8K1CNJ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNJ2"/>
    <dbReference type="OrthoDB" id="68600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="218" mass="23733" checksum="0070A0E6E9909B63" modified="2022-08-03" version="1">MIRNESKWGIHHCGRTVRTNTCEEPLVKLKNAAMIVWVKYGFDNMPLKMYNTNVSCAILLSFLKATCVKDIDEYCKQKSIQLSIELDAIRRALQQASKSSLASVAGSVAGSRPASGASSGPHDGRPKTPQSTRSESHAGEEISEASAARAKKELFEKQLDIINTAAKHIKELIAGVCWLDLVDSHGNRMNVDAAGNDRANTILTARQQYSVVSVSTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNR9</accession>
    <name>A0A8K1CNR9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Folate receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNR9"/>
    <dbReference type="OrthoDB" id="567542at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053305">
        <property type="entry name" value="Folate-binding_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018143">
        <property type="entry name" value="Folate_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37390:SF1">
        <property type="entry name" value="FOLATE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37390">
        <property type="entry name" value="OS02G0592500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03024">
        <property type="entry name" value="Folate_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472840" description="Folate receptor-like domain-containing protein" evidence="4">
        <location>
            <begin position="32"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Folate receptor-like" evidence="5">
        <location>
            <begin position="61"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="312" mass="34881" checksum="F166D718864DFAD1" modified="2022-08-03" version="1">MMRGLVGGKRALLTALWALVLLLVEQDGALCAAEPRQAETGTCRSVGGLRFDPAERSMQRSKGLELCSQYRGNTCCNATHMMRLRLKLREPVVAQFNRRCQKLTDEMTCSPCHPFVGTGKIKTVCPRLCDDWFNACRSEYYSFSGSGSLVPCYGNALVCSPLSIIAPDGAGFCSKMGFQVGSEDDSEGHDCFDGSVPRQLGEAEPQEPWQTWLQRLFEEQSDDPSGLFIVALFVPLFFAYRLFKQLRGPAPVDRYGRSLTLEEVRAMQQASYERAFNAAGDDSDSSSSVFDQDEIDERREIEQEEEDKKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNV4</accession>
    <name>A0A8K1CNV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23287">
        <property type="entry name" value="RUBY-EYE2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23287:SF16">
        <property type="entry name" value="TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="1501"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="777"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="937"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1554" mass="170800" checksum="EF1BE75E56DF0B59" modified="2022-08-03" version="1">MQATEAENVDNDGENATVATPQLRARPLLHYKELSLGTQTKKAKFTCVHASENFLACGTSNGAVHLYATSVNRSDASDAKRTFPAKYHLVKMISPPSNNDRIGVSCLSICPAQKRLVVGTSRGVVYGILLTDYNKIGEKVEFSHDFHSGFPVTCLLWDRQGVKLYSACNGGMVALTTVRAGVSAFFGKADTELLLKEETGIVQLDLAKYSRADILMVSSQLRVLLLNLSVTDGNAVQIGTKARQGTFGACFFTSASDEEEIAKRTNIKVFSARPGRRVWVADPQTGKVSATLKFSLTKNPTNFLQSPECQLEEGIQPRDLTINKLSLFQFLPDSALPEKRGERSLLVSWNVGTSVLFLLDPLAVEIVEWHLDLGAIHDLKVVSDTVMVVLHGEGPKVSIVQSCTARTFLDIYAGEDVKKAVELAVEYQINDLPALESLKTQWSKLLETRPDTDNQATKLTAELDALHSKARELHEMYQKTESGGVPGITTAPLQVIFKQRPQQQQQPSQLPVSNVPDLFAANTDNGYGSTAGDKAVTLGTSGLHRTEGYSGVNSPSYSYSRSIYAPDGSTIEAQLIDINEISHGEAVIRDDYMESWMEDIADEIRRFEAMKPDDSINILPALRGTLNHTGAAAKAITTYIPGANMISNLVDTAVNANYSELGSAVFGDLSDMDTLVLDPVDYRPVIKADTYECAVLRIAMSSATEDERNQDSEVLMEAISMDIWDSRLKYISNLPIEQQISLPEAVKEEEDLKVVSKPKKEVKPYQNKKIEALSSEKPATIRKSRSATSLTIDSSPTTAESPTLAIKRNPGVNRHSSLSPDSGRSAQRALMKYIGGGPNCDFERRCMVSGQLATSPEIEPLLKREVCDLISELQSATMAADKPGRHPKKLWPTAGITRVCACLTSMYLFEGDLDQVEMVIKWWLACFDPTAKPEDQVPVSTAPLKSKANGTSNKQGSLKGSGRGEGLVDGDTLPLTRSDWSLVRVLITLYFAVRAGGPSLLVRPATPADLNDDPVKPYAYELGAILEFAPSSSNEPDNSAASLWPVNEAQDFIAKYGVYLNSEVAAHVCNLRKMSGTLNAVLDQVVSSSNMASICDDVINWIAEKQTEKALKTIKETESLCLLLHVLDLLLKKCPAEAVELSVAKYPILAPWNVERCLFGMACDNEDLQKPENVTQTANYFRYLVRLIEVWGDEVGKDCNLVDRCVKLCFGGAKIVGKLFETEDRSNRITWLCRIFNQPVRYKYTHASAWEMCVKNHATVCLVELAHQSLISGSSNEQGLKELDFLMGTIIEKSELSLLEEVFTRLSTIPNAAEIVSKVLHHIENAAGKGDEELITTVIHSLLNSVGTKDGMQILAQCPLLFAASPLSLYQSIIESHVLSQRQLGELDRMLEAVDTQVWAAYKESSRSDGICLAPQVQAIFDLERHMLKTTLDDTKFGKWQSKRDRYESELAEYRHLTGPSLPTNEKMTITADAPHAFVSRAFEYRSSDWGGDVQLHDATCGVCDLPVVIIADDNSNLEVKLLSCGHAYHSMCISDSACPICFESGFDSLIQMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP28</accession>
    <name>A0A8K1CP28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein RER1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP28"/>
    <dbReference type="OrthoDB" id="448250at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016013">
        <property type="entry name" value="AtER_Rer1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="185" mass="21670" checksum="C3B1422B711B3C79" modified="2022-08-03" version="1">MHPMAGDSQGLTEPPFVARVSASFKRKWQHLLDRSTIHVYSRWAFAFFLLVVYLIRVFTLNAFHIVTYGLGIYLLNLFIGFLSPQIDAENEGPLLPSKLSEDFRPFVRRVPEFQFWYSTTKATFISLLMTLSSAFDVPVFWPILLIYFIALFTLTMKRQIKHMWKHNYVPWTHGKQVYKGKKSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP54</accession>
    <name>A0A8K1CP54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP54"/>
    <dbReference type="OrthoDB" id="10253982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF31">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="441" mass="50513" checksum="456D3C61612338CE" modified="2022-08-03" version="1">MRNPSLPSRAKGCPTSIGEAGVELLSLGKSESGVKEPRRWHRSNAGSLRGDSTMLPTKPEDTLSGALSSYVAYVPPRHDEEQIEKVITLALAAMLDAVRRRAAAAQLPRSLSLMTFNVLAPCYFRHGGRLESDDRTAYLSRAQALIHTIQRDQCDLICLQEYWFNPEYQAQFRHAFRGSHYIHTVKRPDKKEDGLAMFVAKHKFDIHHVHHIAFDKAGDRVALMMHVATKWNRHELPLHQRSFLLINSHLTFPHCEIYKEMRLDQINLVLDSIRKYVASEKLEHAPVLMCGDFNDFNDPVHNTVMDHGFSSVFSHIHGREARITHCNHNNREVGVDFIFASHLEGNEKGEEALALERERLQLLPTRCDLWPRNMSDRTRLKRPSFGHNWETLLSPKGPHHEEEAQFVDYWKLVSDHRPLVAAFDVFPPTESQAVELSELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPD4</accession>
    <name>A0A8K1CPD4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPD4"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533">
        <property type="entry name" value="PROTEIN CBG21859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="103"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42094" checksum="A701861F24C19CDE" modified="2022-08-03" version="1">MRLVSATTVRAAQRSLTRAPPHHAPPLLHLSLRSRLPIVAGNVVIQSSAYSLLSLLPGSTSQKESRERLPSPPPLPQPQRLQVHDDCVVEYVDLRAREDTSYTLVLVHGAPGTYHDYRHLIPILQEQSPHVRLLGINLPGFGGSDVAHERYFDRISALGASQVTLDALHQLCGVNERVFLLGHSFGGHTAINLAALNLQASDSSPQVRIDGMVLLASAGARPHRVLRPRERTFTVFRLLQSRLAPVRYVLPLALKAFYTTILRFPSQFPPSHFVAGVVRAATTDFSTLQTQIAQLRAACVPTLSAWSVNDEFMEDEIPAALAAALGSSRRVVFEGAGHNLQKTRATQLAQEIIQWTDHVSCVNESQCDGTQLIYDDVVLHELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPN2</accession>
    <name>A0A8K1CPN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011126</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPN2"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="692"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="84"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="85255" checksum="737A494448F1D37A" modified="2022-08-03" version="1">MSTDPRRLRAENRHLMVSDEYSLLNTILYTSARSILAQGPEALHQHYSNRMEKAMGRALPQMEVRFKNLSLSTDVPVSGNGNDYELPSLANTLKNGIKGLVSGNKDRATKHILKNVSGVFKPGTMTLVLGQPGSGKSALLKMLSGRFPLTKNIQLEGDITYNGTDRFELADRLPQFVTYVTQRDCHYPTLTVKETLQFAHECCGSELPERDERLLNQGTPEENEKAINAARAMYKLYPDVMIKQLGLEHCQDTVVGNAMLRGVSGGERKRVTTGEMEFGNRFVTLMDEISTGLDSAATYDIVKAQRSAAKKLRKTVVIALLQPSPEVFELFDEVLILNKGQVMYHGPREHVMPYFRSLGFLCPPGRDVADFLLDLGTEQQHVYESPGVHGRGFPRAASEYVEIFQQSWLHQRIKDELDSPHDPMHVHDAANHFNHIPEFHQTFWASTLTLMKRESKVILRNKALLRGRAVVVLVMALIYSSLLNQFDPNNIQVVLGTVFPALLFFGLNQTRQIPLYIAAREIFYKQRRANFYRTPSYVLATTVSQIPLALVEVLVFSAIVYWICGFVSDVSAYFVFQLVLFVTNLAFGAWFFFISSLCPNFNVAQPVGMLSMLLYILFAGFLITKDDIPVYFIWLYWLNPVAWGLRSLAINQYMRPEFDVCTYNGVEYCKNFNKRMNVYLLESYNIQTEDHWLGYGILFLAASFVVYMSLAAIVLERVRHESPEMVTIDKDEDDQKMVILSSCTSAEIDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPR9</accession>
    <name>A0A8K1CPR9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPR9"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="45745" checksum="6385027CE0B2A0FA" modified="2022-08-03" version="1">MANKEFDVIVYGATGFTGALVARYLLQEPESLPDAPSAIKWAIAGRSTKKLQAVKDQLKLKVSSVDAAVIDAIPVVVADSSDEKQLVDMVLKTKVVLTVVGPYQLYGEALVKACAENGVHYCDLTGEALWIDRMVHKYDAAAKKSGAILINCCGFDSVPSDLTAMLLADSVTKTKNTSTAEVSIYFTDLDTGLSGGTLASAFATFDNSTSAELARMKDPFLLCDEKTQAQKKAAGLTRANQSSMGLKYEKDLGRWSSFFVGGDMNAAIVHRSNFLQKNAYGDTFVYRERMSSGGLIKQVLTTVGVAIGGMFLYFNLTRALVRRFVPKPGEGPSEEVMQNGKLVAQGLAYDGAGVLVARSTTIGTSDPFYSMTSKVIAETAFCLAKDELANSNVQRGGFFTPASAVGVHLAKRLHDKRIMTVDVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ04</accession>
    <name>A0A8K1CQ04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ04"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30509:SF9">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN MDTO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30509">
        <property type="entry name" value="P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="639"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="882"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="926"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="976"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="989"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1109" mass="125447" checksum="77E9AF67C958B4ED" modified="2022-08-03" version="1">MTPPREKPIDEEEAEVAAPEQMDVEVDIDADPYSSVSTPRMKATKSMRIRMHKQKSDPSGMRPKHIPHKFVSKVKRKIKHLGNPRVAFRTDLRLAVRIALGVLLAGVAQTRAPEGSSKHWFFMPESYIIGGLNWAAIMVIFAASRTIGGAIQQMWQIAVGMVIALLFNMLMFSLIPMNQEKLIKASLNLRGEDYWISVQDWGHVVPLLLAFTFIVFLSPMEENVKKFAVSTNLYFMLTIVSPMNPIYPTQLKETGPGWFSVHNLVQNFAWYSVVGIIGTFISLATMVLPYPLVAIRMLKNHIHDSPFEIREILNVIVDTYCFRARDIREMDFFQLKLDRLMKAAQKRLETMQELLDDSWWEEIVGGGWLFRFNKTVAKQYIRLYAKLLIDLQAMRLAIEKEACASSHSKIMSQLQRRIYLLQVETNDLLEAIAANVLTGSRAMPTSEFNHLELSLENLLHKYTRIYGDLLSTHQTSRDVSSSMPMNLFLYSFHTLVQTLFEFERTFNEKNYSSRYRMMNFLKLAVRSFCTRASYPRSRIIFTARTTVAVFVGVVFSTFIFGFSSTVPNAIAMVAQYRIGGTYGNIVNRISGLIAGTVIPSIFSFFICKSPSNILYNAINNIVLFVWTSLSMYVYYSGSYISSAGMISAFMAASVLIDHSCRSQTGFKALSYSSLTENSLGILILLLLEAIFQPQSARKLVRKNISDFLSEYSDCLDKILRHHMAMERGISDHEGMTVLDTAAVKELRRLLMGTLATKLEDQTMLLKDAALEPDLWRHEFSHVKYTHVHQMCETLLSNLRILLDLVDWHESRRVSRVDITLQQPTPIGSKRFFNTVNPSTRRVLDQEWCKAQDDMVGALSSALDTLVALYSEQFSNTNAEDTAIFMQMKEAFRLADVHRHGEVDASELAVLLERLLPYQSVQENKPRLDQYVAEFMRLVDRDGNGKISYTEFMDALNRGFRLELEIYEEVDPTTGLFRQASSVESEESRSLQSKESGESDATTAPSTGRSVITTANGPSFSPLISSTSVARLPASSRTDVSLRPDTLLNVESFPIKDAARKLREAYGAYLIVETKAHHVAVEDFILMSCLITTMDEIAAALTTLSSLAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQD2</accession>
    <name>A0A8K1CQD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQD2"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010463">
        <property type="entry name" value="DUF1057"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47533">
        <property type="entry name" value="PROTEIN CBG21859"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06342">
        <property type="entry name" value="DUF1057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37197" checksum="F9D6C7F02B542F51" modified="2022-08-03" version="1">MRVLSTSLRVLRRPIASLTRPVRVAAVSFSTDKSVLPESQELDIGGRYTIKYIDLHPTKRDGKHPTIVLFHGGPGSYEDFRHFIPLIQENARVIGINLPGNGGSLIKATDRKSYYNDIQAINIGHAAFQAVTQLCEADEAVFIVGQSLGGHTAINVVALNEKDRPVNVRGLALLAPIGLRIHKALSPTLNSLLWRILQSDIKAIENVSREFVRFMFTSSGFRANQDIEFYVSGFVRNASTDFDLIKTHVQSIHRVPTLCAWAKNDAFVQEEIFCEMSAQLPPGPRFAFERGGHNIQKTRAEFLSQQLVEWMQRVLEDENEAKKETRDIVGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRK5</accession>
    <name>A0A8K1CRK5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_011065</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRK5"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="61"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW67445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="524" mass="56328" checksum="673177F0D65E1BA5" modified="2022-08-03" version="1">MAPTSFASLDPEPSLKPVVVDFVGLASPTPLQEDDQERVNESPYDSMTVNRILYTSVALALLHPMQIGWAVSQLNLSTFHDQDSCNARPVAPGTCVMFPGHSNGEWSWVVNLWIAGAVLGSIGCARLSDRVGRKKALALNAIVIIIGAAIQASASSLTIYALGRLVSGVASGAASALPNSYINEISPPHLRNRLGTLYQIMVCSFIILVSASFVFANTSTGWRYIGGFPIVLGGLFLLGAPSLLVESPAWLLEKGRRDEAEQELARLFGEHNVQLALSWLDPHDSSDATASKIEELLETPEHGNQAPASPWKTLFSPEYRLQTIIAVVLAFGQQVSGINVAFMYSSSMFKDAGVQDDRIGSMIVNVVNLMPTLFAGGLGTRFGNRRMILLGHAGMGLSCVGIIFALSANSPGISIVFTALYVAAFATSVGPLVYVVITTMFPNALRASGTSLCLFSNWSGQMIIGIGYPYVSDALGALAFLPFLVMLLCLGLFHYKFLPETTGKTTEEVQEIFRSRRRNKSLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRL2</accession>
    <name>A0A8K1CRL2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRL2"/>
    <dbReference type="OrthoDB" id="62482at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="971" mass="109089" checksum="14667929658C1B15" modified="2022-08-03" version="1">MAVKTVAQAISQLGAPFLGQFIEDLIYTIESLARDRLQHEAAVIESRALPHSPHRLAIGASTTSACEGSASDEAEGEATSSDGEEDEEDTDNHEEEEADQNQTPVASSPVPVIDRCNLPRGTMFRTTLRSRAFPPTRVPPVEFIRTTCVYTPFELCKKPPALSSMRIQGRDENGSAEWAVVLFPKNKPSLANADEFAAFEQWARTRQKEFDETHHLIDGSSHETLVERLKAQLALKETVCYEFCRFVFDKCPTTARFLHGLFVELVEVTLRTLGNAERDAMIMEQRHKNVQLELTRLHTQLRTVRTSLGTLQETLARRHQQLLHERECIIRKRKTLNQLLCADQVLIRRVMALVQRVQEIADDVTQAQMMPLASPGGNLLLGAQASEEEMRFPVANELFVWVQTKYDSLEEVNCTAQQHERGVNTEALGEVVNNASETGKDVIVLDLNDIKTASDALKNTLLRLMRMVSGKSPDSAVGWDAQELWDQALFIPPHEDVQDLERDVQRLVRHVEEHVISRRWAQCTVARRNAAVQTEIQACVPKKRTLEMPVSRPRPQELVEDRIAQWHWRLKQRRRLRNADSSATGSIAADSASQDDLLRTLVPDELRRYLPSALPPDYTPHQLALHDVHAVISYLFNHMWLLVQEDLQQHPPHSRFSFSPMSAFSSVLPLAGVHTYLYRIYLQHFRIPAVVTCRLLDLLVSTSHLDTQSGKVLLFARLLGLPGVAPLPSDGFWFLLKTIHVLQRACGSAGCYFLLDGSGNNEFVPQASASEALGLLFASASNDVVKRLRLKLTGLASVYGAVWIPAYSIVTFIVDEWGTMQDALRHRVEQTLLLTRLATSENTTTLPTLATFLDGLTALELRVDRLDAISAYRELLQDSKTDASRFQLLWVQRVIHAVNRTQQRSLTSRGLSGMPGVHLGAVPDAFMIANDRLSIKFLAAGWEAIKPESIRRLSVIFQDVGLQCRRCECLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRV0</accession>
    <name>A0A8K1CRV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRV0"/>
    <dbReference type="OrthoDB" id="108594at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="677" mass="77002" checksum="22FFCD8A08FB8CAB" modified="2022-08-03" version="1">MDDEILSEGEQIYEEEHEGEEEEEEEEDDDDDDRKKFNIRCGPWAFLDGDFYRWFNHVQFAYAPCEASQSLRFGHFRYYLPWVLEDSDKRRKELREDRESLELISLMLRADPSSWLYILNERKPCFTGFDPLAFDQWEMIPRIEIRMHQRYGSEDDEEGAVKQCRHFLLESDHTTEGVQLRTRDPQADYPFVLEHVEIILRTEFLDDTLDLLKELLSLGVPVTLNSDGTAWAIGPDERIRIMTLFASNHGASCPVAPAAHSFRLSGYVSDHFIALMSAVATSDRLHDLTIDEIFGSGDTLEIQLACARWLAYACCSRASRNSLRALTLGTLRLNEACMEAVMEVIDAEDPALLLRDVPDPPEYPNQFAKVEDQAALQCPLGDETWFSAGDLHISPASMYRVIGRDISKALLQIIVPGLGPCLIKQSGVQVTRLDVSNTSPSQISSLDISSANDDQCAPELIMAIGESLQVLQFSSIQRDRVNNGVITNILASCPNLRTLRIDRANWTTVDPLLRYYGRPSELCRLTSLCLWGVVLPSFEVERLMEALANSESLIAHKLQELVLAVVFPTAESPGLDEKCARKCVSMLQSNRKLEYVQIKVQSDTLQALKTEFASLNGYLTSRRLEKLPIRQKCAFFSVIQHPDNRSRAVGQLDSRCMSRIFGFFGFFRPRRVFIELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS41</accession>
    <name>A0A8K1CS41_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS41"/>
    <dbReference type="OrthoDB" id="68676at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF8">
        <property type="entry name" value="BAND 7 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="75"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="48054" checksum="EA2B63B0898DB6FE" modified="2022-08-03" version="1">MSGVTRTMSQPAPTLTQSRYSRLVQINVGKPMDAMKVFNAKTTDGKIPLVLIPSYPKIFTPFMQVPSGLWVLKQKWNAHTGMMDPGLKMFWPAWNRVSHIVTKQAVSYATWVRNCPTSDNVMVDIDISISFQIGPTEDDAVRFVYCLGAHRFDELLHSLTEEAIRGLVHSVRHDQVHDLREEFALGMKKDLNIKLNAYGVFIHNVKVTDVALPPALSRTLEETTAFKTRMEEQEKNHENRMRILLNEETQKITALQKENERQIQDLIAIKARTIIRRDEMRTVAEAKAEVTIAEHISKNDNRIKEAEGLKEDAVATATAETVSRKALPMVELTNLQKDFEQYVNVAKIKSEAVVKAAVREAAKIQATADAEGNSAAFLAEKRNFDYQTKKITLETKLAEAVPLVISGKNGDDLIRQTFLQTLDAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS49</accession>
    <name>A0A8K1CS49_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">U6 snRNA-associated Sm-like protein LSm5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">Poli38472_007409</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS49"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="7"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="85" mass="9385" checksum="169B37B370AEECB2" modified="2022-08-03" version="1">MSAGRLLPLELIDKCIGSQIWIIMKGDKEFVGTLRGFDDYVNMVLDDVTEFEITPEGKKEVKLEQVLLNGNNVCLLVPGGFPSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSM7</accession>
    <name>A0A8K1CSM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007588</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="560"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="595"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1113"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1143"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1185"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1253"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1351"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="74"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="774"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="712"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="731"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1377" mass="153362" checksum="C5C6A07AB5269246" modified="2022-08-03" version="1">MYELRQPLKPTIGHASAKDLMAHGPEALHAHVSNQLETALGRAMHQMEVRFHDISVSADVVMASSKSTTNELPTIANSVRKSVGGIFAKKHKITKHILKNVSGVFKPGTMTLVLGQPGSGKSSLMKILSGRFPMSGHVQLSGDVTYNGATTDEMRKRLPQFVSYVTQRDTHFPTLTVKETLELAHEFNGGVHFSKRLASTLSKTAPEETKAAVEAVQQLSEHYTDVVIQQLGLENCQDTVVGDAMLRGVSGGERKRVTTGEMQFGSSLVTFMDEISTGLDSAATFDIIKTQRSVAKNLRKTVVIALLQPSPEVFALFDDVLILNDGEVMYHGPRDQVESYFADLGFVCPPERDVADFLLDLGTRQQRRYEVTRRDASQLPRKASGYASIFRQSRIYNDMIQYVNGPHDPALLEDKKELFELVPEFHQSFWASTRTLMGRERKKMSRNPAFYIGHLVLLALIGFLNASVFWQFDPKNPQVVLGIVFGTVQFVGFSQTAHIPVYMAERDIFYRQRGANFYRTSAYVMSQLACQLPISIAEAIIVGTISYWLCGFVAEAGAYFIFLLVLALTSLIFTAMFFFLAAISPDLHVAEPISSVSLLVFGLYSGFIMAKGQIPDYFVWVYWLNPVGWGVHALAVNQYRNDHFDVCVYENIDYCKQYGMQMGEYTLRLFSVEPDRAWLWYGIIFLAGGTIVFMALAALVLEYNRYESPHNTMLNGDDDNSSKKTDEWDTESGSGSGQEASSEYGLITTPRKDGHAVVDIHRSSHHSRVTPITIAFRDLHYSVPNPTNPKEDLELLKGINGFALPGKMTALMGSSGAGKTTLMDVIAGRKTGGKIRGQILFNGHPATDLVTRRSTGYCEQMDIHSDASTFREALTFSAFLRQDSTVPDSAKYDSVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLVMEGVRKVADTGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGDRAGELISYFEKVPGVSPIEEGYNPGTWMLEVIGAGVGSTANEDVDFVEVFNASEKALELEENLSREGVGRPSPLVGAVKFEFKRAASEWKQAKFVTKRFLDLYWRTPTYNLSRFMVSIFVGLVFGLAYLRDTYDTYQGINAGEGMVCMTAVFLGSITYVSVIPFAAQERASYYRERASQTYNALWYFVGSTVAEIPFVFASCLAFMVLYFPMVGFSGAGNFFFYWFIISSLMLFLGYAGQFLAYALPTIELATIVSVLILNFFFNFMGFNPPPTAIPIGWRWMYEITPPRFAFNVLSAIVFGDCPVDNPDAIGCARLNDLPPTLPPNLTVKEYVETVFEVKHSDIGLNILYLFISIVFFRVLALLSLRFLNHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTP7</accession>
    <name>A0A8K1CTP7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTP7"/>
    <dbReference type="OrthoDB" id="167655at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="708"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="736" mass="79112" checksum="BDB71DE5F5449CEF" modified="2022-08-03" version="1">MTMTSLAPKGSGALVTPDEMLLLVMFPFEDQVVIIQTSTSQTIGELEEFVVDEYARVFPTRPALNRNLRIQKCVPLDLAVNRRKRTASEMESKKDHSFVDLSKSVQVGNVFENMEQIYVVFNRDQHLATPQKPITVSPAPAEVNGKKKGKKQNGVDKKPTAGSSDAPEHSVNQKKKEEVSNKKAKPAQPEKASTDAPTATPPAKKAKITPVKASAEEKKTNAASASTTSEATTATSEQGTTTKKKRGKKAAQNDAVAPVTATETAPVEASQPTKKGKRASIGKDGEDNLPPTKRSKAQPTTDAKKPDAGEDEQSEPVKKRRGRLPKAAAADASASGDKNEQPAVKEVSRPSSAEKSNFMGNLSVSDRVALLRERMQADKHTEPETSGKEADVATSKEKKKQSGKSSTVENGAANSTDEVKEKKTPTKGSTTENGKKNAKKDTSEQPKEAPKKKVTKTVDDEKNKKVTDAAEQTKKDAPKKKVTKDVSSEQDKNPKDADVAPADVVKPAAKAKFGEFLASKRMEIEAKKKDISNPSSKKVPTTSNGSTTSSDSDFEDVTPRKASTTIKPITTPKPSQDSDNESTDYDTPGPVKVKSTKGNNSDSDSSDDDDGLDYSQNLLAELAPSESAKKTKSTPSKTDSTKKTKPTKTKITLPEDESEIAPESSQETVSDLSQDLLSQKTPESNSVLVSSLRKNRFSLNTVPVAKLKKSAKNPFSKTGNKAAQTGGRRRKSLPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAT3</accession>
    <name>A0A8K1FAT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAT3"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF418">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="52990" checksum="A4AD1014A0FEF3C9" modified="2022-08-03" version="1">MAETTDAFHEVVIIGAGVAGLRCAHQLIHEKGVTDVLVVEAMDRIGGRILPNTDFIPGMTVEVGAEMLHGANTTLTKLAEEQKWSLREIFTWAQGDGGPTEPAPDGGIGYYYLGDQKRMLAYDDTDPDFCHFNDAVEQLCEIEDIDAIPSNESMLDYFRKCNISESMMRLADAGYANTAGSRLDDISLRITCRYERQWIELEDDGDYRIVPTFGRVIDFFKQGVSVQLSWPVATIDHTDPQRIVLTSKSGERLSCRKLVVTVPTSVFLDIEYLPELPEAKQVAVRSFGMRRAAKVFMHFTDSFWPANTHGVICSDCFLPEFWVNSTQGVGELIENGDEEYPASKSADQEVQYLVTGFAGADCADRLHLLTEEEIVSRFLSQLDMIYATEENPTPATKAFVKGMYLDWGDVDYVKGGYSYPRVGQTDHASKDLADSIDNRIFFAGEATSFEQPGMSVHSAMDTGSRAAKQVAESLNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBS5</accession>
    <name>A0A8K1FBS5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBS5"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="384" mass="43395" checksum="F9ADD874C59B13FC" modified="2022-08-03" version="1">MNAGKTLYRAIRSGAVDSYDGVKMDWQRERQYENRLDDAKVIQQWTNRPLSMAILRAQFDQPVDIEGHKLLDQRLDAAFLALREMNDHNALIDNLTAQGAFAAKKRSSSVQYRVGDVVDVKDVGRGVIVSWSEERAHAFGKLHVTYDVLPDTSYQSDRSRLHQVPQDEIELVQDATPVHHPSVVLFFDGFRHGRHTPCASLAQRFPEDLTSEDTEPSVDIPHTPSILQLQFADEDKLTSYLRCNDHTITQLALAALEGKWISECGDEAQQQVREALKEVEQGNLRVARNYLEQVVEAFPSYAYAWSKLGTVELRAGNTSKALQHYERALDLKPHMMDALAGLGTCATRLRRWNVAHRAAMQLLRVQPSNETARLLLDNVIVSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCZ2</accession>
    <name>A0A8K1FCZ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCZ2"/>
    <dbReference type="OrthoDB" id="79694at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="604" mass="69236" checksum="1486ACBAC708ED52" modified="2022-08-03" version="1">MDELYFVDPDQAVEQLQSIHEEMYRASKEFDSCRSLPVADHALGMGKTTFAHHYVRLCLKTWPIEATRTDFRQTICAAHTVMCRLESGVFVHEVSAQVTMNDLLAKAVRRHLSPETELSVLTPPLSTSPQTFAEDLVAAIGPLFIVLDNVGDAFGDGNLDEKTSRDRFAQFCKDVLLSWTQVPGLVFVVLGHAPFLRFFKSMNSSLNAKPWYLERLPLFCLEPPQVQRILRHTLHKAALPETLVDRWGLTSLELEEDATSVLFDLSGGHPGTIMRFLRDYTTYESFKLYAIGDNWLDFYRDAWRWRGILQDWIVTFRLPRGNTRIIDLSRAEMLEDDKWVDISYGEVMRHCHLLWEGTLIEASVFAHPVVEDAIMNVVLPLNLYALRVCEMAPRRTLSYAMAFQWMCVKRLQDLIDQLLVPRVASPLFFELEKRECKSMIVKPRVEWALPDALMMTRMPASEEKADSKFDVFGGPNERSTKRQRKEMETLTVGLLTRKAIDNLDMVEGCRKFHELFVSLDAKTRREFGRMTNVLIVCATAYSDDLPSFSSKDDGFVSMDVPPECGNVTEVLLLNLTMNEKRDQFFGWEKDEMLVDAVETIVTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD25</accession>
    <name>A0A8K1FD25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013874</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD25"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="243"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="ELMO" evidence="4">
        <location>
            <begin position="624"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="860" mass="96416" checksum="17B6BAB8B3A69311" modified="2022-08-03" version="1">MEDLSDAFLDSLDTLTTLPAGKAADVTSDSQSSQDLSDEDYDRATHVELQPVIPIQTRVAQVEMALGVHSSRGVATIAENGDEFEESEQEQMDVITELDSTGSHNTDVFATFYGDTVVKVSRLYNGDGNDRSFSFASECTEFSPINSPQEVSFADDRQTNYEQRLEASVADHASRSGRGDNSETQSTGQKQFTMEDLRYFDPHFGRDVFLEELGESFVDGSGSRSLVSYRVSSTQVTTESASDVIKQGWLMKRAEVVRSWHKRWFTLRRMPQGLMLTYSRSDSPNAQAKVIDLTSTSRCMVPQKPSKENEFRILTSADSSRKEYAVYAKSNFELTEWVRAIQSSINDGNKNICDGGVGFQHIWDETGIQGLIVRYGVRKVSARNHLQTRVLELNFADQTIIISRRGETLTTLHFSDLLGVLIPSPNPKWSNEHHGLVLDFNGKHRSWPLYLDTAETRDDLLDILQKVASKDVRGDDLETRCSRLRLKSGYMERRNVGPQATLKGRLFVCLYENSIVFYPEVVDLKCSRPWYVVTLRGLKVVCNEGKGGLGLGRLLLKCSSVQECREWYNAIMGAISLPQEVVDVELRERGKIRSAFHTSVFRLRKLLKANVKPEVNGPPKDHKTIDLMIRKLWELTFPGEAFTSNADPRWQEIGFQRGGPASDLRSSGLLGLYCLIYFVTYPSGEFTRILDRTRFGVSEGNMKNYPLAIGCINVCSILMETLGFGDAGSHSERSSPSAMKTFVRFIANAVSGHALLDEIERGSLSGQALGLFDRWEEIVLEADNHVFEDIFCILFPVLDHLFVEMGAGYMEFGQVVAAFRRRIGVIFDAQPKTLDELKTLAAEPCTDTLVEPSIISKTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDB7</accession>
    <name>A0A8K1FDB7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013288</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1630"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1739"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1632"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1660"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1671"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1683"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1826"/>
            <end position="1836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1836" mass="200274" checksum="5E6FDD163E49D3BA" modified="2022-08-03" version="1">MALNPPKCAVNMEQRLAALRHDQEIDGLRVYLIKYNLFPRNRDPHNSPIRIEELKELVKHWKLHRQRGFWRDHPEKEDLVRALLQHLKSEATNKKRRQEAQEKYNNRHKNAGLGATANGPGMEMSEAAKRDFSMILLGGKDREGDADDLTATGSPAKATFLKRRIGGDLFYQRGDYDEGMIYLSRIDPSRFQNEAENPRNELLTTTAASPTPIEHLVQMGTGNSSGVPTLRGGMPNHTLHAMNSSESTAVDSGPMSHVTTLEMTSAATSSHPLPTTTHLTREMKIKCLEGLYNVSCHRGFELQMLKEGALATIIQLLKTDDTLLRLYAATTLLNLTAPPHKPSQSLLAAVKDVYTKMMDDGVLGALLDLTHTPNASIKSFCARALFRFTIDETHHFRMVHEGSVVALTQLMTSVPNEEMRQACMQALVNLAAIPRAVTCDAILTTILALSKIGIERNDLALLQRCAQALLNLSLLPTTRANMIDEGALPALSVLTSTSTHWPILETMSCVLGNLAAIKTNQETMTKMGAMVILSELLRHVTRAFQELEAQEAAVDNVAQDDDGEVRAMVRAMLQRVRRNCAHVLAQWCCNSKVQLRVLSAGFVTTLLALIKRPLCPEDLTTKPLEEETEKLAVLALANLALEDRCRVAIVQDGAVPLLLGILQDDPGSEPTTRTHLTLLQLDCVTALSNLMLHPKNFNRMVDEGVVPALLVLIQHSTSPEIQRACVYAMLTLAKDPTMKTRLASITASDEIEDASSSPGAIPVMLVFASKQIQDSELCGVALSFLYHLSTRSENYEVLYFEGAVGFLMRVLQKKPEKGDAVAQQHTLYGLWRDALMALSQLANHPEKRATLIDDGALEAVNHVLRTLAKAAEAAVTRRRDRRLETDAVMLQFSCAQILCKLQPLCCASKSEIPAFCASLLLLAAQSSAKNSRLEKHALATQQKTVLRCALTIARATLMKRGLRLLAAQGDLPPALNAIMRTGLHEAQICAAIALCNLATQRSPPTTLKQYPLRLWKDATTEDFIVITLLRLNSDETKEICSKALFNLLTHDELRDQMVKDGVLYALIKLARIENEEMRDLALRAIYNLSLLPRTATQLLEMEIVRTLVKMYQAEWSKEMKRFLCGILSNLSSTVVGYDAQILSEGALSVLKHLLKVREPETRVYAANILYNLSCAGDVADTLVRDDANVLSLLSSALPSENRDVRRYAAMTIANLSGHALAIQLMTEQGSGNETTSNHGIVRVVHDVLKRTMASCLATSRACVLALRNLLTVGANQQRFIACGGITTLAAILACPEMESETSTLHVATDLLCALANLEEGDDGFEVRLVKDGMIKALLAIATGAMANNPDGSASTSVAERTVVMQIITSLSNLSKNAACHDLMLRDGVLETIALLARTSADTRSPFKGLTGVKGEEFCHHCMIALRNLVHQDEHSDDGPKDANDRNAIKAQRIGSQPSLVPMLLALSQSSVAETREHVVVTIHNVAMYKRCRMQLLKHDGVKALLRLGTSSTSAVKRHICGLALQLLSQQDASEDPHAASIAQDGLVAALNALAESQHAHNDVLMVAATAVRAVLAPRTKAKTEAETSLVAPEYKPMTQQGAAPDWNKVVILSMETWPALETLTTAIYSGQDEQDAHDEAYSDDDDDSDHEHSKHKDKASSPPKAAPLSPVNSRLRASSSILSTNTTGAASTTPSSSVTVPRTCSSDTVLGTLHLLEDLHLDKVKINLEVELAAMQRRGASRGTDGNGELPMLPRPATSEETERESLSLPVDFKSPKKRGVSSSSSTLSLVRHEANQSPQHAAGSGGSPIKSPISTPKRKSRTLVPLTSSASSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDK5</accession>
    <name>A0A8K1FDK5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDK5"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="529" mass="57968" checksum="CFF52325DF4FFC3E" modified="2022-08-03" version="1">MAPTENTPLRGGVQTANAAQRRKRVLAIAAIVIVAAVAIGFWVVDRKHGDNGTPAKVGKSHDDSTPAPQTPTPAPEEILVPAPAVPSPSPEPLTKVSPVTAPSPANASDVFCDVTKQEAGYITLANKIDDHYFYWYFESRSNPTKDPLVVWLTGGPGCSSVMALLTENGPCQVTDDLKTVLNPYSWTNNANVLWLDQPSNVGYSYATDLDADQDENDVSDNFYAFLQGFLDKHPELEGRELYITGESYAGHYVPAVAHKIWQESKNASADSSRINLQGIAIGNGLTNPAVQIAHTLDMVNNTYNVTLMSDEDYQHAKEILPGCIEVGKEVFETRNASKIQDLEGCDLVISPFKDSHRNPYDIRLPCGDVADATQCYDITSVNEFLNSADVKERLNVPSEKQWLECNSSVGLSFMTSGDVLVNYESYVADLLNDGNIRVLLYVGDADTVCNWYGNKAWATALEWEHKDEFNAAEEHAFLASNGSVDAGVAKAYKNQFTFLRLYNSGHMVPRDQPVVALEMLGKFLQGETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEB2</accession>
    <name>A0A8K1FEB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46159at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357">
        <property type="entry name" value="COP1-INTERACTIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="3523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3635" mass="389069" checksum="23B5F1CDB5A7C022" modified="2022-08-03" version="1">MQSVGMRTDMSMMTFRGRTNAVIEIGRRMCVSDEEWKEKCEAMKELKTLVGEYALVQQKKPSETGESAVTQPTTDRMETLFTVENIQALVLPFRTIVLDLRSLVVKEACETFAQFVTTLGPNKCKILVRDVFPSLLEARGGANKVNTSSIHSCIENIVRTTPSRFILAPVLSTLTTTKNRDLRESCIGYIQLAMKSWPKSQLDSFKADLQSVIAAGLSEASQKGREMSRESYWKYIEMWPEETESLDKLLDYGVKKHLKRSRKEEKGTTPAQALKRRHLSTITNTVAQGNASEALMMHDEDRRSAMFRYENKLEEQRATISRIVTAHQALQELLNQKSEENDNLKMEIMETAQESKCLKEKLRNIEARCPEPAETGHTEELLDKLSELQTKLDEYNDKFTIQNLIREDLEEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCRSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDVESKLVSATSAAGDQVSSLLSEKASLEDRVSEQEQELLSLREARESQSAALAALAEEKAALSTQVSVLEASKSEAVDQCTSQSSRVTELESELESLRAKLSDLQKQCGSTVAKDRVPVGGRSTGMESFAMKRTASGSIDPSPLLSKLRRVEDLPRNPSVAHGSAACEATSRPNVSRISGLGSLSLMFGRDQSEIDAEERRLNEANLLKRRQRRQNRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FED7</accession>
    <name>A0A8K1FED7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FED7"/>
    <dbReference type="OrthoDB" id="296632at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12422">
        <property type="entry name" value="RRM2_PTBP1_hnRNPL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021790">
        <property type="entry name" value="PTBP1-like_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15592">
        <property type="entry name" value="MATRIN 3/NUCLEAR PROTEIN 220-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13893">
        <property type="entry name" value="RRM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11835">
        <property type="entry name" value="RRM_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="277"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="395"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="476" mass="51799" checksum="0A4604E3A53BDB45" modified="2022-08-03" version="1">MASKVLYFEQLPSHWTEDKLRETLATHGEIRKIVLLRKRNAIYAGYNPSTLEPIRTNSLQALVEVADVETASTMLNTFQTTPLQVDERVITVSYSKNQELRERHAVGSASRHAPGESNRILLVTVQNPTYPITTDLIHGVFHTYGTVEKIVIFVKPVGLQCLVQFASLDEAVAAKHALNGLSIFPDCCGLVIHFSNLPQELIVKENGLRTTDFTNPNLPVPLNDTAVNSGNDFTPAAMYGYPAPMAVAAAAAASMVGAPMMAPPPIIPGLGREIISPVLLVCNLRETVTCDHLFNLFSCYGNVARVKKLAGKSDHALIQFASQLAAQSALVHLRGFTLLGRSLEISYSKHSYIAIRPGAGGAESDATLMKEYGHGVNRFTGKYANGTKHIYSPTKILHISNLDESETEEQLKGHLSSFQGGDHCKVKLFTNTNGHVQALAEFPSVDAATNVLAQAHNALLGARRLKLAFSKKTMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEH1</accession>
    <name>A0A8K1FEH1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEH1"/>
    <dbReference type="OrthoDB" id="207369at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852">
        <property type="entry name" value="OS06G0298400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852:SF2">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="40686" checksum="4BD2ACA3B53D9150" modified="2022-08-03" version="1">MTATEWEKYVDDSTQTPYYYNTKTGESSWDVPEGYVEPEVEEERASDAEERPEKPPRWRKYVDDSTGDAYYYDEANERTQWDEPEGFVEEDADEDDNDDNEEDGDASDPVAAVEEDAEAKDESDASADKPQTAAPETETPSEQHTWVKHIDRASGKPYYHDTVSGKTQWETPEHFTEANAAPAVSAEYLEYLNRSRAEQLARATQQALDPHGHLSRLNAVLSKIDPGSARPEDVGDEPEAADVADRARAEWQQHVDPSSQRYYYHNIVTGVTQWEKPDGPIASALGGDDYWASVGAAPDREGRQMSAFFDMSKFEENREQAKRIKEELKRKNIDWKKVAAEKKAKKKKRNSEWLFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF11</accession>
    <name>A0A8K1FF11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF11"/>
    <dbReference type="OrthoDB" id="111864at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010488">
        <property type="entry name" value="Zeta_toxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239:SF0">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06414">
        <property type="entry name" value="Zeta_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="56"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="576" mass="64920" checksum="086F4B135BCFAB80" modified="2022-08-03" version="1">MAGMRGLWMQMAASTGRLRVNKRTELWKRSRAIHSSSFWLQRSSTADATDVDDEQIISALVVNRPGTLAQIADVFGYAQQNISGLSVRSTVVPELSRVTITCRLRESDVAAVQKRLRALVCVTFFHITTLRSCIDNNELLLRSHALVHVSLASHQSVASLQRVLEDFDVEIVFGDDNAVIPEDGLHMAEAEEQLHVEALHATASKPSRKTRTLFLHLTAEPSQIDAFVAALKHQEYHIDELQMCGPLFLDMAQSTLDTAMETSFSRSVVQEVERFLDDHEVEDDVRTTHRRSVPPKYKIEGLDDMEDEDEVLMRRPPTTFQLHCNANGHFTTERLQLHARIAHQLYESTPQNIVTPKFVLLIGVPGAGKSTILSHLDTTQQLKISDFVNFDVDDIIALLPEFYHAMLNIGLGNTSPVSTNATRKMTRLPGPQQRYQMCRDEARFILKKNLHSAIMCRRNIILHGTGKSFSHYANLIDQVKAAGFDAHVVCLDVPLELAYDRVDKRSAGYGRDVPRLLIDFTASLITRNFRRLAGRVPNAHLFASDALPPRLVWSKQHAQVVQTDINDPIQQKYELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFB1</accession>
    <name>A0A8K1FFB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFB1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="156" mass="16800" checksum="74BE42A105A5C428" modified="2022-08-03" version="1">MAAADVPGRLLITGASCKLGLVILHHLLHTLHVDPQYIVAGTSSPDSDVLQIYKDQGVDVRYFDAKDPASVFAAADGVERALLISNRENDTSASHALAMRGLVKAGVQHIVYTCLQAADVSLAAIAPIHHTSEKMLEPSSVPNYAALRNLRTCYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG65</accession>
    <name>A0A8K1FG65_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG65"/>
    <dbReference type="OrthoDB" id="159562at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="30774" checksum="4D299E903BD9DE9B" modified="2022-08-03" version="1">MVPMPPPPGAASPESNDEREQQLRREMERAVDCNVCLGVSIYSRAMLEHRKDPDCKGISMVLKASPERMDELRERAAKPRSDNFTLYSVGLSMYSPDWMKTGVRVPAVRGLGMMVIRTDPDELMKRMEQHKRIKRELEDENDDDGGDLVIDFGDEDENDDDGSGLVEKGPLGSMPTRPPRLPPVLPTMSLEDLARQSVENAKTMTRAMYNFWAKRLDGFGERYQESCRRIFQQMSKQARAIPNSITWAHGKIKEIEEQVRGGGRDGPEPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGK3</accession>
    <name>A0A8K1FGK3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGK3"/>
    <dbReference type="OrthoDB" id="107303at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="719" mass="81497" checksum="A68134D1861F7CF4" modified="2022-08-03" version="1">MRRWDRVLPPLVRVAQASRRASASATTIHGSWSEGSAIVSSGASQLRTYSASAEQVSVADTSSSTEATKAQQEQYKRETKKALTDKILLPQYSYHEANEAHDELRQRNLRLQERHYLAIMEKANVEQRYDVVEAHYQVFCDDLEANVVSLHRAAKTAWPHLTSERVQMHRHVLWAMLHGGSTTRFRRMQRFFRRHVLNQRNQINVYESDSLNFLLRMECTLKLSAPTQGTDSANDGWLSRVETILKEMRMLRYNTSYSSSHALFHFLMHRPDVALASVAGTEATQEDTLPTQQEDTLIKVLFELMDAYRRPLDRDSRRISLAISTAASAGRMRVAIALLQDAESRSIPIDAASFAHAVTGADDEEMRMEIAEHYLRAKEHDRLYDDADNHSMKNYLLLYAVHDGNFKQLMELLHEMEFHKIEANNVTVRALFASIARYRAAMRLEETPIDQAQPACPTMLELLNDFPHVLPRTPHSVTSAVLQSLRAGDLDVARLILRTTVWSTDVVVRPEIFSQVMYAFLASPPSPTTHEATIEVEKLYKTQHPDHYATLNAQLLNLCESNQDVATMFAVLDRWQQHAAVGGPLSRRGLQRVFDIVSKQLKNLHHHDADGVRYVVQGDAELSFRAILERYPHIITLDAITLNSAVFRSVTAGLQGDAVTLLQVAHAQQVTLEPTAYKAVVELLRDQSDSLLQECIATMQATDAWTIATARYPELEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH52</accession>
    <name>A0A8K1FH52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydropteridine reductase</fullName>
            <ecNumber evidence="6">1.5.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinoid dihydropteridine reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000716</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.34" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH52"/>
    <dbReference type="OrthoDB" id="1204at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004155">
        <property type="term" value="F:6,7-dihydropteridine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070404">
        <property type="term" value="F:NADH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05334">
        <property type="entry name" value="DHPR_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000157">
        <property type="entry name" value="Quinoid dihydropteridine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15104">
        <property type="entry name" value="DIHYDROPTERIDINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15104:SF0">
        <property type="entry name" value="DIHYDROPTERIDINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="24927" checksum="C2D63008A0DC5394" modified="2022-08-03" version="1">MAKRLVVIGGAGALGRGVISRFTRSSWKALSVDFTKNDESTSSFVFDKTSASTLTQASHILEHANKTFGKVDAVVCTAGGWAGGSVQDADTLVNLAEMHSKNTESALLAAHVASQLLNPGGLLVLTGAAAALKVTPGMISYGISKAATHHLIASTVESLPKDATVLGVLPLTIDTPMNRKFMGDADFSTWTSTEEIGDKILEWSEASSAERPQSGHLVTVVTENNKSTWKDVGNPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHH4</accession>
    <name>A0A8K1FHH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_006928</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHH4"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000391">
        <property type="entry name" value="General transcriptional corepressor tupA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00507">
        <property type="entry name" value="N12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="13">
        <location>
            <begin position="12"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="12">
        <location>
            <begin position="214"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="483" mass="53741" checksum="44C4968798F76047" modified="2022-08-03" version="1">MSSSMEPSTWPEFLVFFVHRHFNFRYPELDAVLTMQGLQLVDAVPDGDVSALPDPEASPLLRIRLPSAAHAKFLSTRGILVKGVYEVWGHTTSSSYEALVKAVDAYAAPQKQQIIQDEQCSWCIGVDAFGKKLTMEEQETKREHFQDVLPFAGPVQVKTPDEKFLILEEYGLELPDLKTALPRQLYFLREIAGSERNRGRGGARDLIDQQTLKRRAYIGPTSMESEMALLMTNMALVQPGDLVIDPFVGTGSVLVPCATHGAVCFGTDIDIRVLLGTGVGVSGAGATEQDEASRVNVVSNFKQYNLPLPELIRADNSLNPLVRRCAGYFDAVVCDPPYGIRAGARKSGRRPGSNTMSTEQLAKKAKQTYVPPTQPYAAEDVMKDLLEFSAQTLRVGGRLVYLLPTTYEYTDADLPRHPQLEIIANSEQKLTKKYARRLITMIKRSEAREVDMEEASRDDVSFANLREKILAENRKRKALDLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHI3</accession>
    <name>A0A8K1FHI3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHI3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40524" checksum="588BF30E92CB30EB" modified="2022-08-03" version="1">MRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIEMNCLDSEEEHDFQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVAKKLREEIATMIPELVEGKIKVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVISAYALARATHVWGPDATEYKPERWVDETTGKVRNESAFKFFSFNAGPRICLGMNLAMLELKLVLTSLLTRYQLDLVPGQTITYDNALTLAVKGELFANVNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHS4</accession>
    <name>A0A8K1FHS4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHS4"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF1">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="14"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="36536" checksum="B4CA27A52053FF0E" modified="2022-08-03" version="1">MRAIRVLKKGDCRSEPDVLVLSDDVEPPTLVPTGNELLVRVLTCSVNAGDVKLMTGALSLPGKTATLPYTPGLEVCGVVEAVGAKVNTFQIGDRIIAAVRPHAVGGGGMAEHVVVESGLAAKVPSTLSPLSAVSLPLAGVMALQAIKDVNIQKDSKVIVLGASSAVGSMIVQLAKHAGAVFIAGTTTEERLTSTLPLDLVIVDDNKHDKWWDVLQGKELDVVIDCLGEANAWRHADKTLKSSGAYATLLGDLLSDGDVKATTQMISMGLVNMWKAFWRASPKFKMVSAFPSTALLGEVIERVVDGTITPLIDSNSPLGFKTEALQQAVVLQRGQQVSGKLVMQISEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW1</accession>
    <name>A0A8K1FHW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Auxiliary Activity family 9 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW1"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482331" description="Auxiliary Activity family 9 catalytic domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="5">
        <location>
            <begin position="41"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="273"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="360" mass="38469" checksum="6940EBBA4C926279" modified="2022-08-03" version="1">MKVALLVASSAMVAQVHAHGYMSIPTPRSTDTFSDMTNTGACDRSQVGKVTEFKAGEEITVEWTRNNHLGGFIRYSMVPRNQANKAAFDKGTFFYTCRETNCTLKQCKDKWCGDDAGSKDHQIKCSSKVKLPDYLQAGDYVLQWTWHSAGSSYGNVGWNTGNYKTCADIRLTTSGTGTKPSCPTFVGGDRVTKMENKPADQCFYFEQNDLDTKEIKIGTGWNNKEGMSHYKYGKPKEIEKCGGGAAPAAGQGPAPVPATGANNTAPSAGGSKPSTGATPVPATSSSPSWSPKPSSGGGRPPASSTPSWSQKPSNGGWSTPAPWTGENEGPGKVKPPVEEGEGDAAQRPRRKHQKWGGEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIR8</accession>
    <name>A0A8K1FIR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIR8"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="45"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="316" mass="35291" checksum="D2D4911C081A305F" modified="2022-08-03" version="1">MAAFHKLPLGHTTKNQELFLAYEQINKTSTDNNNNNNNNNGLTYVCLPGLGDLRNQYRFLGPLLAKDQHGQPNIVYAADLRGHGDSSPHFDDYSVNAGAQDIIALLKKLNQEHGKQQRFVLVGNSFSAATISVVLGRELPHLDDLKDQIVGAALVGPFVKNYPADKWFRPLTHVLFGARWYGVAMWTMYWKTLFMDTEKNPADFKDRVAQLDAKMREPGRLQATARMMRASKEDSEAVLTKFGVKGSATPLKVLVVMGDQDPDFSDPVGEAKWITDKINEAGAARVTCESHIVANSKHYPHVEYPEEVASAMLRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ72</accession>
    <name>A0A8K1FJ72_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ72"/>
    <dbReference type="OrthoDB" id="10066789at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470550" description="Peptidase S1 domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="256"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="52081" checksum="A62EE9BECBCC7D32" modified="2022-08-03" version="1">MPKTLLSLVLATLLSLSVHAAASSTPLVALGSTERPQACVGVQISPLHVLVHSTCATGSGVLTTARVMNLTMPTLNNKSAQATMGPTVAVVNSTIAPLKQPATANVTTSTSSVHVLTLEKPLSSSSPSIVLPLRSPFPNYLDVDRNASLLSVDLGSMQVSWTHQVVYVANSSCEAPVCALPLEVNDRDVVSQRKHWSFLLRHDASRDAYRLLGLGGNPVTDHDGIWGFAWLPQALPNLTTLGVEGVNQVVSVNKEIVGGKQVETTSEYTEYIAGLRSEPDGDTFCAGSLIAPRWVLTTAGCNFSKPSWVAIDTLYTKGKATEPVKVKRQFMHPDYQRGGMGSNFMLLFLERASSRKPIALSRAGDDKINYKGTVFGYGATKYKLKKMNHRLRSTKLQVYDLWSCPVEIRPRLDGTTKCAFGKACYGDYGGPVTNNAWTSDRRLFGVVGTQMTCRAEDDFVIIGFVRGITDWVDEVINNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJS3</accession>
    <name>A0A8K1FJS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJS3"/>
    <dbReference type="OrthoDB" id="1585644at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021832">
        <property type="entry name" value="ANKRD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055285">
        <property type="entry name" value="ANKRD13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447:SF25">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11904">
        <property type="entry name" value="ANKRD13_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Ankyrin repeat" evidence="10">
        <location>
            <begin position="179"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Ankyrin repeat" evidence="10">
        <location>
            <begin position="623"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="482"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="737" mass="83249" checksum="C3A004F2385D3209" modified="2022-08-03" version="1">MGTTPAIPPLHAAIWEGNAQRVRQLLEDASHVNNPEYGRASERQAESRVKELLEARDAHGNSALHLAVRVVQPPQRAIVELLLEHGARVGSRSTEGWSCIHDATLCDDEFLLAQLFLKGEKQLWSQFNEHQEDFLLALERLPDFEIEIFVETYSWIPGVSKMLPSQTNRIWKRGSQLCVDSSMKGLERFNLNHGNISHIFMGRGDAKHPGGRAVILNHDTKTFYDITKAIHTSSTLTKMDLGVHLLLTKELSMTSIDGSGLEFKKRKDAKSITTRKKTAGTRRACPFTGTKYEMKNFAVSFESRAPVNPQRQQGKFATTGIEATDEAMEKLQEYVDELSLTSSSRGLSSRGNGSSRGNGSSRGGAIRDVVIDPNEDAHEADLGQSAWLAKGKRMEMHLDVLAGDVITWTFKCKNKEFSFTGTYYSDDQERLVCRSDGVKNTAIAGTFVADDNGSFVLSWKNTQRGFSLDKKKIKIHYTVEHTRPAVPPPSSSGRTWSGERRESLMMAPPEEYTTDDEDNSNTRSRRGRSTRREPTDLELCQQFSRLDHFPNPLIATMSFSDYFMVDVEHKHEKAPPPPPVEKKKTARSRLMRRSKSQEMPSFPDSPISDAYVASTQVNGVEYRNTYRNLTVLPPSKRFRKTFDAKVFMAEDFPFQLTDFLPVIEFLSKTGDKVQNLAEFFRMKLPPGFPVRFELPMMYTVKAAYTFQKAELRSDIDPALFELPSDYRQVFAVKDVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKG9</accession>
    <name>A0A8K1FKG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKG9"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421092" description="subtilisin" evidence="9">
        <location>
            <begin position="21"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="177"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="519" mass="54519" checksum="B7505D683580AB8E" modified="2022-08-03" version="1">MVLSKFTALAAVLAISGAAAAPRIDPSVHRTLRQQGTVNLIVTMRDSNDSPLQAAKEASFTSCGAQIEALVERLSAHAETSQKDHEAVIAHESSASLFSESRTFWIPNQRYIKDATVELVEKVAAVPSILEVREEQILHLPKIVPSSANTTASTQATNEWGVEKVNAPKIWAGGNRGEGIVVSSIDSGVLATHVALKGNFRSDHGWFDAGHKKATPYDEVGHGTHTLGTIAGANGIGVAPGSTWITCKACRTEEEGCPESDLLTCAQFITCPTDVTGNNKDCSKAPHLVSNSWGSGQDDTFYKAAVNSWHAAGIIPIFANGNDGPACSTAGSPGDYDNVIAVGATDSTDTIGWFSSRGPPVKGLLKPACPLLVSMCARLGSMERPYSTPSRAKPGLTYDQVKDALIKGVDTSSIITAGEKCGNIKDSVFPNNVFGSGRVNAVKVLGGSTAPAPTWAPTPSSTTRAPAPTPTTRTPAPTPTTRTPTQAPSSCSDLAFVDCFFADACFWDWSSGQCVDFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKP5</accession>
    <name>A0A8K1FKP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKP5"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000286">
        <property type="entry name" value="Heat shock transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="20835" checksum="9E56E152C41C5F0F" modified="2022-08-03" version="1">MTKATRELAPFLRQLWDILEHESPDVIRWTDGGRAFEIHNLQKVIDTVLPKYFKHRRYASFQRQLNYFNFRKWTKSRTAVSTFSNPYFVREAPELMWHIVRKRDLNRSRRDLAPIAIQSPKELPEDVLHSPQDSTQDPSGLFAWIDAEFPSLASLEQLEKDPVAVPSLLGFDLSVVPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKQ2</accession>
    <name>A0A8K1FKQ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKQ2"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.410:FF:000002">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="511" mass="56233" checksum="67CD2AEC932D4EC9" modified="2022-08-03" version="1">MSLNEQTPLNGSAPSLHSAAREATRSRLVRVALGSVLAVGLGALIYSASNSSVAVAVATSKAPNSPAAVVQGVPSGDESWRCGNGTQEAGYVKLANKIDDHYFYWYVESTNEPATDPLVLWLTGGPGVSSMTALLTENGPCSVNEDLTTTTNPYSWSTTANMIWLDQPTGVGFSYSTTSEDDDKDEENVGENIYWFLQGFLDKHPEFEGREFYITGESYGGHYVPGAAHYIWKQSKNESAIESKRINLQGVAIGNGLTNPIIQYEHYVDQAFNSYNISMLNDEQIEQMRKDQIECIELTKQCQADPKNGTICVDAEGCWNFKLVAPFSAAHRNSYDLRKPCEIVDKVGGMAVCGFSFGPIQEYLDLEPVRKFLNVEVPTWTQVSAEVMQAFVSSGDFSFSYESYVADLLNDGLRVLIYAGDADLVCNWTGNQAWTKSLEWKGKDGFNAAEERAFTTHDPVIQDAPAVHAGTLRSFENFSFLRIFEAGHMVPTDQPAVSLEMIAKFFKNEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKY0</accession>
    <name>A0A8K1FKY0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKY0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426405" evidence="6">
        <location>
            <begin position="18"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="215" mass="22480" checksum="D57C375349D15C3C" modified="2022-08-03" version="1">MKLAAVLIAPTVAIASAADVGGLDPNVTLPACDTQTLLKIVRSGNSTACTAETGFTIAILKPVTSEDAPKVCGQKSCQAVFADVKDTFKSDCMALGLPFYKYVIEPTEEACAKYSANPLPPCDTAALLKIMHGENSKTCTAETGFSFGILKPVTSEDAPKVCSQKSCQAVLAEIKDTIKTECIALGVAPFFGDVIKRTVDACAKYSAGETPSSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL31</accession>
    <name>A0A8K1FL31_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL31"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01301">
        <property type="entry name" value="RGSPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="198"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="456"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="74266" checksum="5D4CC954A775CE2A" modified="2022-08-03" version="1">MGAMLGIHADHHEISELYDRSMLLPLIGSDQRDKVIRNARLKKAHERQAIPHQETQVMLIVDGSIDLYKASSKLHTIYVSSHEEVAAPETSLQTAARRARYDVTGAESQADDDALAIRTREVLIYWRGPEDVVCRYSCRSSSDEIILKAAVGDRVEFHGRTRYISISLKYLAAKTGVRKTINAVTNADLVELVGDIPFFAGIPREHLAMLTELSTLRVYPPKSVIFREDEGVSTQMYVTLAGTLEVSSSRASAPLAKLEPGSFFGEMSLLINIPRAATVTTVDSCLLLSIEKPAFHSFLENLPDVKLNVYKLLKERLLFKAMKSGVIPYFSNVPTARLIKFSQDLDIEDHVRKGDCLLDQEDVNSHKFGLIIYGVLEIVSSEQKRAKTHSQSVFITPGCYFGPFTFERLNFQRGRVLARSSVVLLSCPFSRVKELFDEYPEVAAEAHVAWFGERCDLAAVLRHAILTQRFQAFLEAEHSDENFMFCLDVQRFRSTPREERRQLAILIQQRYIQPDSPKEVNLPAVIRDQIVSTLKKTAVTDDVPVDFFDTANDEIMRLMKKDSFPRFKKSPMFQTVVDALDPHLNRKGSKLMDACHAFRESISLVHPGKLEHASMARMQRMLSTIRRSQQRQNAVAATTGPEFRRSRAKLRHVKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL48</accession>
    <name>A0A8K1FL48_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL48"/>
    <dbReference type="OrthoDB" id="157561at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="43638" checksum="896B03FD5B68B04A" modified="2022-08-03" version="1">MASAAVDMRVPADERGVVTETKRRRRSAGGARKRVAFTGAEYIEYDSTAAPVVRRAGVGRVLRRSPASATEGATPPPLECADREAIALEWQARRPRGLRLGRQKDDDLDEEAKHAAVIQQYEDEMREMIESRGLPCFEEDVADLPLQLRITELLVAWAAVADLPEDKTLDPKTSFDKHRRQLELCRKHVFGPVVDGYAFGRRFFSIESYLGTLELEELAELAEARGLTVPELTPEERDAVKVTERELIAIFSPTGVGKQLKALTFRELVEEAYARGIDVDEIPDNKQKRSKRAWVDRLRPIVAAEMKELKLREAQSDLLFEQLLSVMEEAMQATQLSTIHRLIQLHLSASDTSRSELSREDMAMNAAVARYFRHFQQWYQDHHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLB8</accession>
    <name>A0A8K1FLB8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLB8"/>
    <dbReference type="OrthoDB" id="122776at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="37842" checksum="4F2DA2559DC0B132" modified="2022-08-03" version="1">MVQKATKTRSVRAADAASADLQRHSLPHTQLPLATKTTGWVILKKSTRGVLAAFMASARPLAVLSVVAGLFWLAVKIVGRFQLWMTAAGVLMVVLSVASAVQEVMVKQVAPSSVEYLDEECSKIAIATSDKTAEEIPVVMDVPQTHAVAASDDVALNMASPALVDMTKQQQPTNETSVKPARRNSSTLELGDNKLLVVHCGTVINVQGSRGFIIPHNLPSKPSPKAATRTAYSPSPLSKLPLVIPFELSAVLAALRPEVTVGKTVEFSCAEDETTSRETVVAVNVRPVATDEGIVKSRNALQTCKQAREASFAKAMGAIKRITPRNVPVKHPVDLIKVAEHLDDQESPIDHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC2</accession>
    <name>A0A8K1FLC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDC20/Fizzy WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009281</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC2"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000025">
        <property type="entry name" value="FIZZY-related 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="10">
        <location>
            <begin position="541"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="586"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="628"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="669"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="717"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="805"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="372"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="866" mass="95888" checksum="2B3CB464398B407F" modified="2022-08-03" version="1">MRVRPRGQWRARSSVTKSKAMRVGTPDTVCEDDELSIEVSFASNGPRRHEIQAPQVEVIDLCDDSDKEETDSLRRGGILPTEFWKEAAMSRVHPYRKAGIRRKEPSGRRSPMTTDEAFKLRHHYNVLQSALTQEDRVNDSNWLTSTFIDLMLWRLASQYHHTHFLPTDFCHFHLPSVFRRAGKAKVSMSDFDVRDVLGRPIEFADTRPIVFVANVGGIHWNLFRVQFEPQAELQLFEPMGRLSSRTGISYRSIPREVLQWLDVCYPEHQNWRGRTVSAITHAQQISGFDCGVACLLAMRPLDHQYAARLERNENNRPPQSGGVDSWTDLGCQSSPLPHKTLKRSRHIYSDRFIPSRLSTKLETRFELQSEPSKYAVSNNQNDSPTRTSGDSISNTAGANGASTQCTNPSGKDISASASTSYSMLLKSELLGIEPPAQSIANSYFQYMDSDYDMYSPPTARSMLRGSTAFDFTSNNGTRPLYTAGPSTSQNMLRFKSSRSAPLSDLKAASIPFSGLGAASHRMISGPSATRRKIARTPFKMLDAPSLQDDFYLNLVDWSSMNVLAVGLASCVYLWSACTSKVTKLCDLGPSDCVTSVAWSQRGTHLSVGTNTGHVQLWDVASGKKVRTMTGHVARVGTLAWNSQLLASGSRDRMIYLRDIRSPAMHQNKLVGHKQEVCGLKWSFDDRQLASGGNDNKLLVWSLPASCGAGASVPVVRFSDHTAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTHTNTALQAIDTGSQVCNLMWAKNVNEVVSTHGYSLNQIIVWKYPTMAKLATLTGHTFRVLYLAMSPDGQTIVTGAGDETLRFWNAFPSSKGKGGGRLGTSLLLPLGPNCNEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC5</accession>
    <name>A0A8K1FLC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_012092</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC5"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="559"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="658"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW66976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="706" mass="80334" checksum="D67DF8344B638C67" modified="2022-08-03" version="1">MDRENRVVMIVRASRPGTPSGNNGTFQNRDNMDAIAINMGPMDADAWRQQQFQRQRMQLLSMAIFLCFMVLFFDNRASDPRQNNRNRLDSTSHNRHGADGQNETERLDKIQDFEKLLRMQPGYDAAAMANNISGIYSGSWSSLTADDYEKTKPKYTDIVPYLKIDRDMQVQQFTQPVEVGHTWLLLKMKPPAAKELSDDVSYVKGQLVIYEEQASLAATILPVQGVFFRKMGKLTLFGNSPDSTVQVLYKKADAPSNRTKDDDLNQPLEPPAKTDDDTSFQPHLRLGAMNLGEIDGVPMIENREDYESIDISPPRYSYVSRFRSSDSFSDQCVSVVEMTLVNDTTTAVPKGGEGELSLNNAKLTGTLASVNCGLYLKIETTFQEENLNVFFSKASHYAVIMTFIAMGEIYFLLRQLQITNTQATAAKVSLLTIGQQAIVDSYLCLGHLTVGIVAQNVFTAFASVAFVKLIIFSVFEMRYLLIIWKARRPQGFADGWLTLRRELTTLYSRFYLSLLGGLAIFYNFSSHLPLLVFICYSFWVPQIVHNVHREVRNPFDLGYLYGISALRMFLPLYFYGCPDNFLTAFPMYESKPDISFCYTLSFWMALQVGILVLQQRFGPRFFIPARFLPVKYNYERRINQQEVSLLHTATNDEGTIDCVICMVELDISARDYMIAPCDHIFHRECLQGWMGVKMECPTCRCALPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLD4</accession>
    <name>A0A8K1FLD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLD4"/>
    <dbReference type="OrthoDB" id="10263032at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="637"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="637"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="655"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="766" mass="88252" checksum="71D749F3AF8B4A70" modified="2022-08-03" version="1">MAVATKQLPAKENALFRSVVKCYEMKQYKKGLKAADAVLKKFPEHGETLAMKGLTLSCMGKKEEAYEYVRNGLKHDLKSHVCWHVYGLLYRFDRNYQEAIKCYRNAIRLDPENLQILRDLYLLQVQMRDLKGFAETRRTMLTLKPNNRNNWIGFAIAHHLVGNYQMAIDIVEKYFSTLDENRAADYEDSEIYLYQNMLIEESGDLEKALAHLEASKAMILDTLIWRQKKAEFLLRLDRFDEALALYEELLEINFDNYVYHRGIQATLLKRKDLIETKDQRLPSVYVELTKEQAEVLRVYYESKKDQADSKSTVCLRVPLDFTTGDHFKAIADQLMKKQLTFGVPSLGSDMKSLYASNEKVQIIESLVLSYIKTVEAKKPLVGDAAPSPSVILWTYYFAAQHFDRLGQHDKALDYIERCITHTPTVLDFYQRKARIYKHKGELSMAADIMGEARKLDLADRYINNKATEYLLHADRVEEADSTIALFTRHEGDPQQNLFDMQCMWYEIEHGQSHIRQKKYGLALKRFFAVEKHFDDFIEDQFDFHTYCIRKMTLRAYVGMLRLCDGVFGHEFFVNAALGAVKTYLEIADNAAREADANGGDLSGLSAADKKKAKRAQAKARKAEFRKKEEEELKAKLQKEAEEKEAAKKKAAPTLRNKDAPKDTDPFGEELVKKPALEEAWRFVTKLQQYAKDDIKTQLAAFDVAIRKEKYLLCLQALLRGFKCVGVSSAQKTELEARKSRFLESVKTVTDPIVLQVINDKKAELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM3</accession>
    <name>A0A8K1FLM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polyadenylate-binding protein</fullName>
            <shortName evidence="10">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_005451</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM3"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000004">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000091">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000385">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000520">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 9 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="28"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="204"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="313"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="13">
        <location>
            <begin position="548"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="465"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW62833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="625" mass="68326" checksum="0DF9397245C5A759" modified="2022-08-03" version="1">MANSATSPTSSPATTAATGAAAQPFHTASLYVGDIHPDVTEALLFEIFNAVGPVASIRVCRDAVTRRSLGYAYVNFHNVADAERALDTMNFTSIKGVPCRIMWSQRDPSLRKSGVGNIFVKNLDTSIDNKALYDTFSLFGNILSCKVAIDFNGNSKGYGYVHYETAEAANEAIAKINGMLIAGTEVYVGHFQKRQDRPDIDDWTNCYVKNIPSQWSEEDLRKEFEPFGPISSWVIMKDAGAETHKGFGFVNYETAEGAHKAVENLNNKVYKNGDGSDIELYVGRAQKRSERERELRNKFEQLKLERLNKYQGVNLYVKNLDDQLNDEELREAFGVYGTITSSRIMRDVNGASRGFGFVCFATAEEANKAVAEMNGKLISGKPVYVALAQRKEVRRAQLEAQHAQRVGLLGRGMPLGQPPMYGAAPMFYGQPNQMPPQARQGFVYPQQMLPRGVHPRGPMPYGARAPGAPAPGPGYMPGYAVPMQQARGQPRGRRQGPGGPAGPQPGAPVNRRNFKYTANVRNQPRPDGMPGAPVPGAMPPAAPAQPGLEPLTSAALAAASPEAQKNMIGERLYPLIHRQQPELAGKITGMLLEMDNGELLHLLESPEALESKIQEAIQVLEAHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLW6</accession>
    <name>A0A8K1FLW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLW6"/>
    <dbReference type="OrthoDB" id="127077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475140" description="Membrane-associated protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39412" checksum="523AE270BF6462D3" modified="2022-08-03" version="1">MWSSCVRVFIVGFAVLTTLWSKEASAALTITSTKVVVPDLVGLLYPQHAEHSVQFGSSKSATTYSAAFTTSPSLPTCDSTSFCLDVVVHSAFEFDPFVLVAYESKYPIASETFGNAAVVNEYPNVRPVVEGSGESGAGTGGNPGYLETLWRFNAVNGAQKIDVVFRLRQLSQWNSQKDQAIVHIATQVVDDFTSTTSVDAYVVYGNARIQHKTSQVQQNQVRLDIDITRNASQPNVGSEDAYPLVPIDVSPRTLLWSYGESTCLECTALLYGCTPEDVSSDSCTFGSSTAPLPSCLRSTYGLTSAWFVEMLSYTAGYQVPIKNWIDTCLRNIFNEEFGLDLQWSMRRWFNATRNHLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMV5</accession>
    <name>A0A8K1FMV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMV5"/>
    <dbReference type="OrthoDB" id="47198at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41271" checksum="9BE28200471D6C46" modified="2022-08-03" version="1">MENDSAFVVAAHRADTRCPPSASEGLELAHKRTDALLKAMIANHTEDVKALLECSDERDEGIKRVFYEACRRPSTSPELIKILLEHGADPNSTNSIGYSALSVVSRSGRVQVMHLLLEHGADVNFQSNPNGRAPLSTAAKRGSLEAVQLLLSHGADINATCLKGKTALHYACRRRNPNILLHLIAHGADLNVGDASGQSPLHEAVQLARRKFIPILIEHGADLYSRTTDGKTPLAMSLQWGRKWNPIRTLDTTFALMTHGAVYENSPNNCPTYYGHRKWKKRIEPPNGWPQSNSEETPSGNVEFTELAQAIALCVGHWSKEQQDGKAGMSSVSRNVLYGGLIVVKHHLESSIDAQSSVIDESAFSRTDEPPHGTISSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN83</accession>
    <name>A0A8K1FN83_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012165</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN83"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00538">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PA" evidence="6">
        <location>
            <begin position="53"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="6">
        <location>
            <begin position="285"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="487"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="525"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="575"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="690"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1121" mass="124203" checksum="CBD8E1BB6CB63A24" modified="2022-08-03" version="1">MSSTWSSAPSSPSPCSSSSAAPPAYAFVTWDAALGRRLSFLAIFGSRAEQTLTARLVCVDPPRADLETLANADDVRGAIALVVRGGCSFIDKARRVQAAGAVAMLLANNTREEQFTMFTMADESSPESQRDVTIPCVMMCLHDVRELFKQYPPSVKTGVLTLEVPSTLKAEALYVECEQRRQQLMKQEASGWLTRKTSSLIKRWEAPPVPQVAVETSSITHMSSVTIATESSSPEAPPPAARVPLFAFVQWATSAHDSVLFFAPLADFSVAVEPNAVFEAPCIACDPLLAHQDPIVNAADIRGAIALVQRGACTFPAKLERVQRCDAIAMIVGNDDAEDPDAAFVMSVDQINVDKVAIPAVMVSRNVFTRLQTEKPSRVRVLCLAGEIAAEWLGRQGESIALTEPPSNEQDDNALARFHRACREADIVSCQLLIEGHGASALVHTVDASLRSALHHVCGSEVSDDKADALVALLLLHHARVDKADVLLQTPLHLACLRGHRAVVQRLLGANSSASTQLTTAQNLGGRTPLHYTSEYGHTACLELLLSVNARFDMSKDGSSTDKFSFLGVDTTDVEGLTPLHVACDALQLECVLYLLAANADIDALDHKERTPLIIACERVNDEEDEARKDLALRIVEKLLEAGASCLEPNDAFVLDRIRPVPLRRELELVYLRREAVHARKQLQDLSKHVSQQNERLSALRTLVERLEATVEIQEKKLQKRDERLNRQQRQLEQLQRQLQTVLQVLQGTGSVSGYIPVTPNPQDEQERAQEAALARDVGKKCCRQHAYALAEAHFERSIELFPLPGVARLLEETRELRAKETVTKQPPVLLPVGNEDDSDATTKRRELTQLRDAVQQTHTSEATKDTLLAEINKLEGFSRSSNEYQAATKWLEWLVALPWDADATLSQRLHLERAMFDELEQLEQEAWNQRLHLASKTIQRAFRKRFAEHLMRRVLASTQIQAWYRGVAQRICHETQQSEEPVAESTITAPLEAGACHSRDDDGDLVDLEKMLDPWAMQRIQSEAAIELVTGEYAEDSSTFLVVQLVRQCSNPTVFFVWKRWGASRALARQCQVSGPYDTFETASRRYKRLVESISSPATNKMVDQDDMDTMARSTVARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNK9</accession>
    <name>A0A8K1FNK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011618</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000325">
        <property type="entry name" value="ATP-dependent RNA helicase DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001214">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056328">
        <property type="entry name" value="DSRM_DHX29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056890">
        <property type="entry name" value="UBA_DHX29-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF237">
        <property type="entry name" value="ATP-DEPENDENT DNA_RNA HELICASE DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24385">
        <property type="entry name" value="DSRM_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24899">
        <property type="entry name" value="UBA_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="9">
        <location>
            <begin position="418"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="617"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="860"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="529"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1404" mass="157141" checksum="7C92C351111D254F" modified="2022-08-03" version="1">MQLLHEYCQSKKRSNARYVHARAPEGRFRMRCILPDDKSSAKDLAFCPEQDFETMDDAKHCAALLALKHVDPLRPLERKLPDQYRELWLDLVKDVVPAGAAATTTSADKKPSRGKGKKGKEETKTVVMEEKKQTEVVKSEGDMDLWADTPDSPTHEDKSKTKRPVELTADRKFASRAEYEQAQLERAKHRNDRNRARENRERANPHKQVFMSAACREMIENVLKTLGVVSDGAAGESEGATQPTKENHEVFYAKVTKELSAIGFERKHIQGALQACKKDSDHSDDEFMTIILDWLCLHVPEGELPKGFNPEGTQLDVVVMSNGTDAQSTQTPLSTVLVQRLMKLGYDRRDAVTLVDEHVEANKSRLDVDNDAPTNAQVMQVVHSSLPHLLRHLALDTVVDAAKSAIPDEDELKQLREDELFALEAIYDDKMVMEFIDAGQLLTVHLTDEVDLEILLPSDSKYPFEYPALAVTCKDGSATPFKCLGACANALRSCQNSMGEPMIYDLCVAVESAISEKSGGERIVLFKREAKETASSPPPAPTVIAKDKPGNKKSKQPQRSASAKQPRKKQSVDPAQIKQMSDKLFQQRRAKDSNAGFQQMLQARAKLPAAAERDNVLEYIVHHQVVLVCGQTGCGKTTQIPQFIMDDYIDKQRGGECQIICTQPRRIAAIGVATRVAQERCEDIADIVGYQIRMDAKKSANTRLLFCTTGVLLRRLLTDRLLSGVSHVIVDEVHERNVDTDFLLSILRDLLPQRPDLRLILMSATMNAELFVNYFSSSAKSPCPVLDIPGFTYPVESHFLEDVIAKTSYQVPKKLLVNKKKASDAQDENAREKLVSEMTPQELVARIDDSRIDYELCVHLVKHLVESSSNQHGAILVFLPGTAEIKRLMEMLNQQKEVGSRLWVLALHGSLSGADQSLVFRPPPKGKTKVILSTNIAETSITINDITVVIDTGKVKEMVYDSQLRRSQLLDCWASRAACDQRKGRAGRVQAGTCYRLFSRDRFQRMDAQLAAEIHRVSLEQLCLQIKKLELGPIRAFLAKAIEPPKQEAIDSAMTELIAIAAFKRVEDDSGRQREEVRLTPLGSHLAMLPLDARIGKFLVYGSILRCIDPVATIAACISSKNPFVMSMGDPELQERQQSLKKELNAGSKSDHLLLARLIERYAPVKGQKQKRAFCKDYGLSYDTMETIVELKAQYLQQLDAIGFYEGNKRDELNTNSSFPRIVKAALCAGLYANVIQVVYPEQKYFQSAHGVFTEQHDAKKIRYFVCASTATGPESAQPSAASRERVFLHPSSCNFTQTQYDSPWLLYTELVQTSKVFVRESTMVNPYAMLLFGGKLEVVHEKNLLCLDDWIRFQAVARIGVLIKAIRRKLDELLTQKIANPEVDIAQSELVTAISHLLKSEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPE6</accession>
    <name>A0A8K1FPE6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPE6"/>
    <dbReference type="OrthoDB" id="159093at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424703" description="Protein kinase domain-containing protein" evidence="8">
        <location>
            <begin position="17"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="323"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="597" mass="65103" checksum="D484D1D037DE21DC" modified="2022-08-03" version="1">MLSASLFLSTLTLTHAMDARVAPDVRHLRRLAIEFHEAGSFPDAPQLTDISCALMDLSYIDEATFVENNECATKTTYRWGMTVLPNAQQQRELCTCTALIKKVQMLELPRCLVYISDDIYTYKQVIEYSFARCTSSSGDSDSGSSSESASSSGSESASSTASSSTSASSGSGSTPSAPSPQTTKGEDFFSTLTPQVSSEEKKSGSNVGLIAGIGGGALVIVILIIFLICRCRKKSKNSTTKQGAEFEDLQHVVPSPQDLEMVAGDYAAYGQANNSKSNSKHSATKSTNASSSVPSGGSGPRPTDAGLWDDSMIIAVRIPLEAITFGALINRGGYGEVYKGVYKNEVVAIKQLLPDRRKDLSQIDSFLAEAKLLASLEHERIVRFVGVAWNSLSDLCVVTEFMDNGDLRSVLTRFENEERRQHGFDSDKLKIALHVAHALTYLHSLQPIVVHRDLKSKNILLTSNYDAKLTDFGVSRERTDSTMTAGVGSSLWMAPEVMLGERYDEKADVFSFGVVLSELDSHRLPYWDAKELGTGRRLPDTAILQMVSLGRLSVSFTEYADEDLMLLGQSCVRLDPTQRPTIAEVLHRVHQAARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRV8</accession>
    <name>A0A8K1FRV8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007635</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000362">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="724"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="778"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="854"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="878"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="965"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="96"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="417"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="736"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1057"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW67963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1311" mass="146033" checksum="FF3F90CBEFBB7496" modified="2022-08-03" version="1">MAIKSTARYSTFTSSPRAEGAAPHPYTTAWWGSRLLLSWVSPLMSLGQQKQLDMDDVWPLQRRYQSEFASQQFTRDFETTRSIPKAFFKSFGWRFVLTGVGFFVALLCTLVGPIVLNHVVSSLTSPSFSIEDVSVWVGLLFVSQVFQALVDQFSNFESELVAIEFVGCLKSLLYTKTMRLSAQARMEKSTGEITNIYTSDSDSLLATAYFVHQLWLLPLQISIVVYMLYDILDVAAFAGIGVIVVMLVINRFISKGMFAIQRVYRDSKDARMKKVTEVFKAINIVKFNAWEEKFMERIEETRAKELKDLFTAQLYVAASIVLMWGMPVFISIASFGVYSVVLHRELTPAIVFTSLTLFQMIQGPLRFITDLITMLIQSKVALERVAKFLDMSEINSDNVLSIEDVSADEYIKKNVIVSVENATFGWDESSMVLRDVNLEIKPGEFYVVHGTVGCGKSSLCSALLGEMIKKSGQVYVGGTVAYCSQQAWIQNMTVRENILFGKPYDRKKYEKVLDACALTKDLASLASGDQTEIGERGVNVSGGQKARIALARACYSDASIYILDSPLSAVDAIVQNEIFNKCLLGLLRHKTIILVTHNPEIIASEYITHAVTIDETGKLVETRKIQTRPVYDSAVTPLAAHAYVKRTFEEEPDVEVSDKSDVPSYEEVAEIQQELALASPFKEDKVKSFGVTDAETKEAIAAGKLIIEENRSEGRVGWHVFEGYYHAIGGLPVLTIILLSQVLWQVLQVASDFWLGSWSSDSVSEAGNVASTEYRLGVFSILGLASAFMVVVRTVMIAYFGLRAAKNLFDRMTNSLMHAPMRFFDVNPIGRILTRYGSDVATVDSRIPTSFGTLFARLFSVGTSAVTAAVVIQWKGFLLLPVVFLYYQIGAFYIQPARELQRLIQTAQAPPLNHLSESIDGGSVLRAFGRDQIARFTSTNFQKLDNANKVWYAQLCVSQWFSLRIQLLGSLLVLVVTSSLVLLHNELSPAVIGIAFSYALKVSQNLESIVQSLTRIETIMVSPERLQEYIEIPQEASHRIPSMDPPKTAHWPNEGSIEFDQVSFRYKEGDRLVLQNMSLKIEGGEKIGIVGRTGAGKSSLTMALFRINELASGSVSIDGVNVSTIGLKTLREKLSIIPQNPVLFKGTLRSYLDPFGEFSDDELWSCIRKVGLGDRISNEEKKLECPVEENGENFSVGERQMLCMARALSRHSRIVIFDEATAAIDHETDQKLQRVIREAFEQSTVLTIAHRLDTILDADRILVLEGGRVVEFASPAELVKKGSGHFFELMQEGGYLEKFLSGSPTHSAHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTC4</accession>
    <name>A0A8K1FTC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTC4"/>
    <dbReference type="OrthoDB" id="7875889at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000773">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit beta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34944" checksum="0CFCC7110D214B9B" modified="2022-08-03" version="1">MAETSIYPRGELDGHNGKAVTALATTRENPNLLLTASRDKTLVVWQLTHDGESYGFERRRLTGHSHFVQDVVISSDGQFALSGSWDGTLRLWDLNTGITTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGECKYTITEEGHTEWVSCVRFSPSTANPLIVSAGWDKVVKIWNLANCKLRTNLFGHQGYLNTVTVSPDGSICASGGKDGVANLWDLNEGKRLYSLVAGDIIHSLVFSPNRYWLCAATSSGIKIWDLESKIVVHDLQPEFEQPKGKYAQVPHCISLAWSADGSVLFSGYTDGVVRVWAVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2N5</accession>
    <name>A0A8K1C2N5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2N5"/>
    <dbReference type="OrthoDB" id="124038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="22128" checksum="2FE96DA33D156917" modified="2022-08-03" version="1">MILISRIIHQVSSTLRGLRKEKENAIVKRWKNTDPYHAAPLPKKGYAMQLDHIVEKQCFSYGLTLLKHHNDEEAVETAIGALHSIVHSRKNLCFTLATTNVIKGQACTAYLEDSLMKLVVPEYTVQPFTDYLLAKEKDGSRLERGDTRRIRKTMGRAVKSCQRKLDGQGDTPVLGRLSKELGNLYADMELHVPAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2T0</accession>
    <name>A0A8K1C2T0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2T0"/>
    <dbReference type="OrthoDB" id="111653at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="30095" checksum="675B694C611FA50B" modified="2022-08-03" version="1">MPAESASGWRRDAQARSFASSSPPSWRNHWEDRGYAYMLRRGWGITSRVMRRWNAFEAYYKQGVFAKETTNEERSRMFVLTCMPTKTQVDLFEFLQGATHAVHAVYDELYTTGTYPVVVSEALAQMASEDVLQVFQRKPQRQTQQLAVHAEPRQTRLVLEQLDIERLELIAVDYTTTRLADQVAADRGYEEEERLRLDVVCDVTEHVRVVSTGLAAIDDHSTFQTTFKWSFASNVSESDQLDWTIVDATEFTMKSTLVTANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Y8</accession>
    <name>A0A8K1C2Y8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_010326</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Y8"/>
    <dbReference type="OrthoDB" id="266663at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032954">
        <property type="term" value="P:regulation of cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000038">
        <property type="entry name" value="Tyrosine-protein phosphatase CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="14">
        <location>
            <begin position="82"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="15">
        <location>
            <begin position="167"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW55444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="40638" checksum="19283FD4E10F4B95" modified="2022-08-03" version="1">MTLLALFLVICHNRSPEDTIKPFQTLKPAFGFRDAACGVGTFFISILDCALAVHKAMKAGIWNYGSFSLDEYEHYDQLHHGDINWIIPGKILAFSGPQQERIVLDEKGSTTLLAHDYAKVFQKLGVSCVVRFNEPSTYDRRAFVQANIRHLDMLYPDGGNPPDEILHKFLRTCERESGAIAVHCKAGLGRTGTNIAAYLMKHYHFSAVEAIAWCRICRPGSIIRQNPIYFVEKEKIMVNGTLTLHIRRLEGMPEVEADEKQHIEGMYYVVRVKIGALDHRTQSRGKGQETDMEQDLTFELQDVDGRESVTIEVLDDHDAVLAGAEIATVDELIEGCNKEESYSVHGANRTASLTVSSKWQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3C0</accession>
    <name>A0A8K1C3C0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3C0"/>
    <dbReference type="OrthoDB" id="273345at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="375"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="421" mass="47796" checksum="E1681C19BD30823C" modified="2022-08-03" version="1">MADMAATTNAVDEPNALDASSPAPDKRQVLTVGDGNFSFSLAYLKQQLQRREQLRLVASSYDEYQELLEKYPESIRICTQLQELGADLLHRIDATNLRATLEACASENGEVQLPTTFDVIIFNHPHCGEENVRRHQSLLSHFYASAKELLHPTRGELHLTLADGQPERWEARERGTKAGLVLVEEIEDVDAHPVYSVDYERKRHQNGKSFHRVLLHGEKKQQDSTLFIFARPEAKRPPIAPTTTLKRKADTQDAHEYSEYNCETCVKSFKTAQGLRTHMHMVHELGQGMPSSSNGRYPCDMCDRTFKNEDARRQHQTSKHGKDPQIRPDWFKGDDNDVPSANDQLTCEICGFSFADQAAFDEHWSQLQPKAALRLACHGCKKVFDEERALRQHQNFCRKLEATHSTPTSSTQTPDKASKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Q0</accession>
    <name>A0A8K1C3Q0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Arsenical-resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008512</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Q0"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035427051" description="Arsenical-resistance protein" evidence="11">
        <location>
            <begin position="34"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41809" checksum="5FDDAEED9545D7EA" modified="2022-08-03" version="1">MSASGPLIAQLSLLDRLLSLWLLLSAGIGLGLGQIDAIQSFIESTTIHDTNILVAIGLIVMMYPPLTRVRWNMVHRVLADWQLLLLTTFQNWVLGPLAMFFLAAGFFRDDAGYRAGLSLVGCARCIAMVVVWNSLAGGDDEYCAAIVAVNSILTIVLYSFYATFLLNDLPDAMHLATSDDIAVSMGEVAQNVGIYMGIPFVLAIVTWYWLTSTKGTEWYSTQFTDKIGVCTLVALLFTVLVLFASQSTQITDNLDKVVYAAVPLFIYFIVMFFVSFAMAFLLGGSYPQTASVAFTAASNNFELALAQAISAFGLRSDPALMSVVGALIEIPMMLSLVYVALYLKKRLYHLKDDEEESVDTQEASYQLHKELQETEEAKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C418</accession>
    <name>A0A8K1C418_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C418"/>
    <dbReference type="OrthoDB" id="346371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042410">
        <property type="entry name" value="WBSCR13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321:SF1">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433091" evidence="4">
        <location>
            <begin position="18"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="273"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="406" mass="45383" checksum="BCB40C52DB93C2A6" modified="2022-08-03" version="1">MDILLVLLALVLGLAGAYYMYDQQQKQQAAEAARLAKIKEQEELEKLQKKPKPKRVDITAELKKKQAAGDAQHEHIADDHPWLRHILKGHKYGITAAAYSPNGRFIATSSTDRTVRIYLREALTDPKARPQQISLEYDHVTAMNFSSDGRTLILATVNGNIKLYQKLKAKPELVTEFAVAHKTDVHSVLMNDIGKWATIVTCASDADTDVKFWSTDGTLLQVVNTNQVTNYHCLGSRDNRYIAVAAYTPEVKILEITREKNGTFKKAHKIMSLQGHRTGVMDLAFNGSDTQPVNRVVTTCKDGSLRLWDINVRYALQEDPKVVKSFSPSSQKAFHSLDMEANAKVIVAARERDLVFLNAANGNEFAVIEHAFEDTIKRVMFSPSGDEVLVLGKNAKHIKIYKTPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C427</accession>
    <name>A0A8K1C427_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C427"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF547">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="47"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="472" mass="54570" checksum="2A9F397F96FDDB7C" modified="2022-08-03" version="1">MADTTDVEMVDTQPETEDKRRSRVVRGVRFVKETFQERQGQNVYEAFRHHMQLGENKFRQFEMVRPLHYYAARCGEEEETKSDEPEQYQIVAAFFDPMKHVPSNEPVRLCRTGIVKFAYHFTMTENKKTGKTKTVDHAVAFKIMDRDQLTQQQEDTQRERRVMSALRAEGFRKKRLNPLTEPDERKPTERLYEHFPQWRFFEDAHNEYMVTDYASNGNLLMYAKRRIESYCFDIAHLISTYMILDGFPSLKALTKLWRDEALFIFTGIVRAVVYMHRKGVCHLDLDVQNVVIDSLGNPILVDFGSSEVAGEDGIVACDRPILCKYYYCPPEVREHNRNITQSAGVDGRAADVYALGVIFYWLLFVKAAEGDIYDPVRCDSNWLLNVIHHVGRVVDTHDEEACAICRSVIPVATEDLQILQALLTKNPRDRISAEKLLGIVEERGSQPLGSSFKQSQVVFEQLRVAMQTSSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4F5</accession>
    <name>A0A8K1C4F5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008886</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4F5"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="70"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="54905" checksum="075C513F9897956C" modified="2022-08-03" version="1">MTEEETNELLRLREEKTAARRHGTSTGERRRVGSGEASIGEPAAEIDAETDSNDLKAHGQSVGGIKPRTWMVFSLIGGLIYGYNVSMAAPLQYIRDDLNLTSSQEEVVSATATLSDASSMLIGGYLADTFGRKTTAMFACSCSIFGALMASLFSVDFGWLVFWRLCSGVGNGLSILLLPMYISECVDAEHRGTYLTLYQLGVNSGTAIPYFFMIFVSENWRSCLAFGSFPALYVFYNFYFSFPESISWLQWKQDPEKYDLENGSHNDSKHKQRQRVPSTPSAPSDEPLRSKPRLELVIGILLAYVNNCIDASLFYGPEIISKVLGDSSNREANIFGLTCALLAAVSVVVGVKFLINSLPRRQLYLFCLIIVTLTFVVSGIIFAKYSTEDFANDAVASTSIIVTFVIMNIFAAIGTSMLFIVILSELFTDNSYRARYMSYCTFAMSFISLLVNGTLLTLFEKLGTSMTFFGYGSTYAACLVFFWVYLPETKQREIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C598</accession>
    <name>A0A8K1C598_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coiled-coil domain-containing protein 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C598"/>
    <dbReference type="OrthoDB" id="10261348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17032" checksum="BB0367FFC6DC56C3" modified="2022-08-03" version="1">MGEHGGEEMSRAKRLKLLREAKERKERGETKVEEAVPVVASEDAEMAEETSAKHEDADTAMTSPTSADQSMNAIIEADKKGDEDDDEDMLNLAPKRANWDIERDIAPMLKTLERRTQHAIVEIIREKMAAEQDEEDDDDDDEDEDEEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5M7</accession>
    <name>A0A8K1C5M7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LYR motif-containing protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family. LYRM9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5M7"/>
    <dbReference type="OrthoDB" id="190541at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20269">
        <property type="entry name" value="Complex1_LYR_LYRM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045291">
        <property type="entry name" value="Complex1_LYR_LYRM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052151">
        <property type="entry name" value="Complex_I_LYR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47061">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47061:SF1">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="83" mass="9772" checksum="3C5EF786BC7E97C1" modified="2022-08-03" version="1">MHVPNPKSLALYRRILRASRRLEPDTRDHYRRFARSGYVAHADELDDERVDEIIARVEHDMDWILRKYTGKGLDEDPGTPAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U7</accession>
    <name>A0A8K1C5U7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_002920</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the MICU1 family. MICU1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U7"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990246">
        <property type="term" value="C:uniplex complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036444">
        <property type="term" value="P:calcium import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051560">
        <property type="term" value="P:mitochondrial calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039800">
        <property type="entry name" value="MICU1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12294:SF1">
        <property type="entry name" value="CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12294">
        <property type="entry name" value="EF HAND DOMAIN FAMILY A1,A2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW56995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="323" mass="37640" checksum="145FDFD097638116" modified="2022-08-03" version="1">MRAHIFRTLPRASSVVTTALAASGLALVQNSQQARMESSSPEDKTDLPSFSERMVGNYENRLRKFSSPERVFEYFSSVELNKEYFMTREDLARAITPYTYRSGAPLASKNTKFNFQARSNKPSKDMVEAYTQHVKHLLLEKQNVTTQDVQALLAFREKHNIDFETHVKTLHFLHITNNEFDQFVELHGGPKRERTFFDMVDADGDGLISYDEYMFFNTLLAIPERQFELAFKMFDADGNGRLDHREFKRIIDLMRLRTPAGRQDRSVQDDDAPIFKHLFGELVTETLSYEDFCAFRRDLKKEIMRIQISFLAIHCLPLWIHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C644</accession>
    <name>A0A8K1C644_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">POP1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003056</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C644"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="14"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="6">
        <location>
            <begin position="573"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="722"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="770"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="480"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="834" mass="93128" checksum="BBA330D38A384353" modified="2022-08-03" version="1">MAGVGPQVVQVLEFANARAPELQALHELAHHERMHSAVDAKLSSQRNQRRRRANAFKSHQLPRRLRLVEPAKSTEEELIDLPARGDRSKLKVKQQTATQKEKEERTRCRKHQRRMGKMVEERSWLATPQKNDEKDAELYEKAKWLSTHAWHAKRMLMQERYGHVLAQRRQDKSVSAALTALRKTAVVHDMSYYGVLELYGRSELIMEALQLVSDPSGSAFEQEDLLSGREEGESVLYNVEQFPMGAIAPVTFMWRPLKSDFDGSTGKFTLSSSWQSTKRQLWLWIHPAAFMEAASAISEACQNVMAERGADETIEILDRRGHVSRIKLRGKTSNDLLTQILKPAPRRLEESTAETDHVDEFSSSEVYQYGTKGNFELLHSALHANSRASRTKNNVFAVTAVDPRMTKCWPAANPAASTSLLEEPSSSVVHGQGILCPLSGRDLTSSDNAEEPDSDIILHQLQVLLKWTTISTASSPGALSSLGYPHQPPATNANADDVSMSDNSPPRGNVPCSLLWSLSAREKQRRSFKKDHDLNHETFQRRRQQVDGESIGSSTKLDLLVVGKPAPFPNTSGWDFILTPEYAPVILHALVFGGAMVVGLEEDEAFATIISEPSFPRDFPDTTAGQAYWSDIEETERAMWLRKPTAKRIAYDKLGVASPFQPQWDLLFPSTETDDAPMEDEEEGDESLNVCVLRGEEYMAPFAFSSSLAADAAFVPVAVPTLIRVQLAVPRRGTIEPTSMLYQPTEADLIAFRSDVKWTGREMKPEEDDSLPLLGFITSALYDRPKSAFRALGFCACEPLQRLFLGQTGETTVIALTRTSSSRMLRPVTVTVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6W9</accession>
    <name>A0A8K1C6W9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6W9"/>
    <dbReference type="OrthoDB" id="124652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457317" description="Elicitin-like protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="25356" checksum="48FA6AA2D904B1CC" modified="2022-08-03" version="1">MKFAAIISTASLAVASAYEEAKECRPQDYSALRPLASNPNLHACQDNMGWQLLPPVGYPSSKDLDFMCLVPECLALMNNVKALGLSDCVLNFDGVKVNFKKLSEEFGPRCSGWGASVHASNSDAGNYAPNGSDGSHGSHGSYSYDGSDGSGAYEVPFPGEGSDGSYSHGSDGSYSDEIRFPGDDGSYGSYSQDGSDSSYSDEIRFPDDGSDGSYSYEVPFPGDGSDGSYSRGDESDVITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7L9</accession>
    <name>A0A8K1C7L9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elicitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7L9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461551" description="Elicitin" evidence="7">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="23666" checksum="CDE2106DEE265F70" modified="2022-08-03" version="1">MKTSAILGGVFSALASVGSTQTMSQCADVFVNLVKVADQAGCSEDSGFDLMVFNKPSAADIQSVCEIESCRKMVIDILTIGIPHCYLPWAPSVQFVNEFVVPTYMCTPTTPVKTRAPSPTPTVTPTPEPTTSTPAETKTPEPTSPETQTPETQAPETEVPVTSAPETKAPVTQSPGSTGPETKAPVTTAPETKAPEASSPAPVPSVEATSPPQKPTSPSLTPAHSLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C995</accession>
    <name>A0A8K1C995_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C995"/>
    <dbReference type="OrthoDB" id="62564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF193">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="616"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="347"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="752" mass="85901" checksum="AEC8FA80BA8BCDD3" modified="2022-08-03" version="1">MEEEPDKFVGVKSLNSKQRKPLWEKWPRHCGILVFVAQFVVIMAAGVYIYGHITYFHMHYTNVLSVSIKTWWKGRPEMVRPTYFTVFTIIPLVVTAAMLAFLRQPMTRRVTSQYFFKTAMIMRRKPRCLRWTSYWSFGELLYLCFLVIGNFLVFYFAYDRRYKRLKIQAAAKKTVVTGDAKLQAVAITFGFNAIYNLSFLFIPVTRHSIWLEFLNISYANGVKYHRWLGILTIGFAFLHCACFYSLWIRKKTWKTEALPCFDCPLSSTKGRHAWINIFGEIALVCFLVIGLSSIPMIRRKFYNLFYYTHHLFTMAMIFAVMHYAGILWWIFPTLLLYIVSRTISASSSFAPVQVKELAALDNDIVKITLHRSTQTDGHFHVGQFLYINVPALSKLQWHAFTIASSPHANPTTLTLYIKSLGDWTRDLVTYANDCKQQDVLPTVYVDGYYGSSLGVYEEYSTLCLIGGGIGATPMFAILEDLVSKTRLRALQQRVVFIFAFRDLVLLKQIHPLLVKLQALDPGGKLVRYQLFLSTQANDEVLDRKLHLRQENTDPPTKYEKSRRVPCPFSENLQLRSGRLLATLSAFVFAWLIVIYLEYGGGKIQSGTNTHLWPLQRFVEVIILFAGGIVFPALFFAAERLIKRHTKSASMIKEVAMHGVVLTSSSVEIPSVSIQTYRDLLTEHNAVVGARPDISKLLQQVLEFHTKSVPGIKGHSVIGTFVSGPVEMKQAVACAVSSIGANRFDVHEEEFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA08</accession>
    <name>A0A8K1CA08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA08"/>
    <dbReference type="OrthoDB" id="103326at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF2">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35071" checksum="38D51EE4B61A378C" modified="2022-08-03" version="1">MILESPRSAFKDVFAKRQPVNHRVVGTLGMVSIIYLYTCAGPIGSEPIVSAGGPLAAMFALLVYPLLVTIPYAYIVAELCSAFPEDGGFTIWVLNAFGPYWGFQVGYWSWISGVIRTALIPDTILNLFLAFYDTKIESTAVELFVKAGIAIVLTFPACFGTRNATRLSCFLLVVVIVPFFTYTIWAYVKTSEVGEIFDVRHEVTYYDRDIDDAILEAIATVALLPISFDDLLPLSNAFAAAVEFTIIVAAMRLRMTLPYIPRPTKVPGGILGLLIFAGVPAVVLGYILVHTFMTSLIATLLMVGLLLFGLINGIWSTRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAM1</accession>
    <name>A0A8K1CAM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAM1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15672" checksum="0CA22978E8C3461F" modified="2022-08-03" version="1">MSAFNATRLDKLSDKVQHSSQWLARICSELAKKNHDEGTVAVLLRLQQVLQNEFQAYLQEAQRELAELRDNQNVIMDPEDISTDPEVVTHESTGTASPDVLEKSEASASLEPINGTKASHKLAKLIERKKQRRGIKSYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAV6</accession>
    <name>A0A8K1CAV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TKL/TKL-CCIN protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAV6"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="249"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="569"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="898" mass="100214" checksum="F328C76443BD06EF" modified="2022-08-03" version="1">MAQRLSETGTIMTFTTTGATAAPPATTRLAELPMRVQASKEVQAVCEKILSRLQLLHRQLDHMIMMTATSSTGSNGSNGVAGTKSAQQHKALSEVTELATQFDTFLRAQSTQNIVYRLTDTRRVGGLLFFHEELDVIFRMLRLEHVDPVRQWRAEWAQDREDMEQRFKQAVGATEVLYRELRSPADQIEALAMLRTALEKAQRQNSVDKDAALTTHIDLLKTTFRRLVSFAKVEIPVVPSWFLSPAELSIQDEAFAGGDHVEMCYATWGRFKTHVVIKRLTAASSEDEFYRTKLVDEAKMWSTFDHLHLLRMHGGSPVSSPPYVVLERPTNGTLDEYLQINGENRRLLFKLLVQTADGLKYLHEERRLCHGDLKLSNIYVGNDGYVKLGNFTSFFIPVDSETSVHSGQEPTGSVRWMAPELLDSDASVSVSFEADVYAFGMCILEAASSDLPWSMMPDSEVRQRVLAGEIPARPAHVDDSLWALITSMCAPEPTKRPSMSAVLTQLEQLAAEEAQLLRQGSSVSNESEDLTGTSLDLNKTMFFNEVDIDELISSRSNNPPGSLANSEPVISVVTLHHKWLGIKINSIGHKIVVSTFLRSSSGALGEIEASGQVKLGDVIVAVNNRSVRGMSRHQLGSVIQSTPRPMELMFKREPELLEECFQFHGLRLEERWRDRGSVAPLPGSLERVFGFNEDTFTFSTWFSLNDADDTFFGGILLGAQDISCAEQSWAYCHHQLIMIDPHGNLSCFFLQDSTPVLIAADLSPARWYHLVITFSENELKVYLDGAVRHSARGSLNNLWSKLTHANIGSGCISKAPSNAKPTPDFCGWYGFNGLVHDACVWHSVLPDMAITQLYRGGSDCVDDPFFSLRRDLNKESFGPQVPRRVMASRPHHVVAQTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAZ3</accession>
    <name>A0A8K1CAZ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAZ3"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04332">
        <property type="entry name" value="YbaK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30411">
        <property type="entry name" value="CYTOPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30411:SF4">
        <property type="entry name" value="YBAK_AMINOACYL-TRNA SYNTHETASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="418"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="547"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="699" mass="77640" checksum="9E1736DC4014C99D" modified="2022-08-03" version="1">MATIESVHAQLLEAEKRLAAVEKLLDERESVRRVQQHLQRAKLSSAFLKTAPGDYYSWKLEQRGEFLQCSVPHLCKSIIVDNTACTNAGMEDPLNSRYYCVVLQYNSKLNGEQLMRFVRSRIPEKDRPGRKAFNFQHASGEVAEQLTGFKFNGVSTFGMKTQIPVIVSGAVAALEPPFLWLGGGSETVKLRISVQELLSSLSADVAPELTTLRDDLQQEDTTMASRLDLEARLRALREPKGSMKTSTQPPTSPATSEGPPAAPAPPRAETTSAAPQPMARTSPMPPRFNYYAFSGTTPTPPKPQPVERPPVAVQMPPPPQINVSAILGPAYDDAVTMAQFAIESERKQLVHTSIDAYIRAGQAFIAIGRQQTVPHLQTILKTKALALLQRAEGLEDWATQIIANNRHAANDEAIRAAYAQSQQQEDEMMNEKEALVTQMRTENEEMTQRLNKLVLLTKMRSRLKRVVSERRERKAAEAACAEEGSGALEVETATSNEDTPPETERPAPMSTESSSPREEQKRAIVNELHSLIGLPEISHLRTFKPLSADARRERRQEELERELEQARREAEELRAAVQDMEVALQGSNVNSFSSDQAPEEDMTQLKAELERLREELAMERQMSSRQMGPVEFEDEDIITTLRKSLQGLNNGDEDLLNKALGREEEPTGAPRGTSSPRRKLLSSQSSGDSASESDDGVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBM3</accession>
    <name>A0A8K1CBM3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000378</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBM3"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0820">tRNA-binding</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="TRNA-binding" evidence="11">
        <location>
            <begin position="323"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="275"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="53532" checksum="2C79A6F529D37253" modified="2022-08-03" version="1">MMQEEASPKTLPSPRATVPDVAFVTGSISLPSAEENTLDEPVSATILRDVRLVAGKLKVVLLPKNTSEETLKALRDWDLWGPLMLCLTLSIMLSLTAPASQSAMVFTGVFVVVWAGAAVVTINAQLLGSTISFFQSVCVLGYCIFPLNIATMLLLVLKVIIHHVAIRLLIVAIGFVWSTRASVVFMSKMVPPKRKALTVYPVLLFYLFISWMVLIQIRFLCDTYFLINEKALFRPHIPVVEAICHQEDVTKMSGSASEQLDKLIRDIETDLGIDANAPLPSDKKPVKKAAAAKEAGAEGAKPKKEKGPKPVKKAAEADADQPEITKLDIRVGKIVKVWKHETADKLYCEEIDVGEDEPRQIASGLVYHYSLEEMQDHRILVLCNLKARNLVGFKSHGMVMCAATPLEDGKEKVKFVEPPADAKIGERIVFDGLTGEPFTPAQVEKKKVLVNIGEDMKTDENGVATWKGHVFQTSAGPCTAPGVPNAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBM8</accession>
    <name>A0A8K1CBM8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBM8"/>
    <dbReference type="OrthoDB" id="77656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037485">
        <property type="entry name" value="PEX22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34126">
        <property type="entry name" value="PEROXISOME BIOGENESIS PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34126:SF1">
        <property type="entry name" value="PEROXISOME BIOGENESIS PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22978">
        <property type="entry name" value="HAD_Pex22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="23935" checksum="49701E82321CC5EA" modified="2022-08-03" version="1">MGTIYVFAQQNQPQTTPAGGQRRGAPVGPPGQAVPQLAANAIATASLTEKQMKLHRSLPSRNGARTITICVDALLRNKTWEMEWVNEDTPKVLADLLFVGDVYLLCKVDGDDKAVTERIQHFITSCEVIEASLEASKKRGLQSHKILFCTTTVGKVAFVRQLEPQVHVEVDPSVVRDLEKHVPRIIHVVPRLESPPASGMHHVTDSFSVYFDMLSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCK7</accession>
    <name>A0A8K1CCK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCK7"/>
    <dbReference type="OrthoDB" id="58460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF9">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="41"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="59605" checksum="01633165E473E302" modified="2022-08-03" version="1">MDAAIRVEEQVETYYGQGGFPKQGRSLKEKIKEAERFLEKEIPKSGIVGVGAAIVYQDQVVLSKGFGLLQANDSSLPVTEKSLFQIGSVSKTMIAVAIGLLVEERKVGWRDPVKKHLPWLQLYDKYAEQHVNIGDLLSMNSGFGALPDIPDVFGAFASEREYIEALQYMEPEYSLREHPDYANVNFVILGQLIESVSGQPWHEFLKTRIWEPLGMNNTYASAQLAPSDAEFNSGHFACDGEVLGPFDITKDRATFLKGGNDRELNAAGSIISSPKDMATFIRLLLNKGIVDDVKLLRSASTVAEMITGKNLASVFDLFPKMGLHYAPDGSTLSAGYGIDIIGQAIWGYPYFDKSGDVATHQTRTGFAPTENLGVIFMGNSQAPDAHVTFYIDHYRTYVMGIFLDVPKKILDFEYQKWRTADKLKPPLPGAPRCGLRFWKDIPFKQLRNEQLEELVGDYTTTTSTKFFPKMTISQTNDSQLTMTLALSSGPLHYLGDMEGDSSTKLFLAKTGLGPIVLPASVSATGQYSFNVGVSYQKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE19</accession>
    <name>A0A8K1CE19_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE19"/>
    <dbReference type="OrthoDB" id="90288at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="42436" checksum="9DE46C8E3CAA4E3F" modified="2022-08-03" version="1">MVITNNVIADYKLFTPLTIGKDLVLKNRVVLSPMTRARCDPKTRAPTELTALYYEQRASAGLIVTEATAVSEQGFGWYGSPGLYTEDHAKAWKPVVDRVHAKGSKIFVQIWHIGRQGHSSFNIKRELVSASSIPATQGRLRDANGEYADREAPRELSIDEIHGIVEDYRKCAQLAKQAGFDGFEIVTNGGYLIDTFLQSVTNNRTDKYGGSFEGRARFLFEVLEAVKSVWPSDRIAVRISPNASNGEMGSADNAEMFTYVLEQLSHHNLAYLAILDGVFGFNFGYHNKGRLMTAYDAKQSFKGRVFGVNSHTRDTAEGAIRTGAVDAVCFGRAFISNPDLVERFQNDWPLNPDAPREMYWDPAKEAEGYTTYPTYGQSKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFA2</accession>
    <name>A0A8K1CFA2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010844</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFA2"/>
    <dbReference type="OrthoDB" id="1892506at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF124">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="5">
        <location>
            <begin position="375"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="620" mass="71251" checksum="230AC66E29F776B3" modified="2022-08-03" version="1">MSESRSRHTNAAVLEVSDAEDAAFLRPETTEHKPSSPRRQWLGGRKRLWLGLAVVCVLVYWSNVLNVRQRLRSMADASKITLLSAEEREKREKDEAELKRRKAQHAKRVADCDAYRDYGMVSVLQRTPKKFCQRNETTTTALRTEATRPSSPYTVYESGNAGIQSTVFSNLWVDFRQAKVFKPIDSIAQDGHLHDPRFTFPSVNVYCFCDADQNTSSVPRVWDEMLGNFPTNDYYTVCRRTTQEQADVLASGWDTTGAMEDGVDTTYNVTRIATNAIVLARRDDHNPFFQISAALNAWMMMKVVGWKPETTQLVYFDDGFPSPIDALQQAVLSPKHPVVPGHDLLKSVVHFDHVMIAPFEMAGPMMRHLDNNEPCGLNKMISDFRKHALQQMNVSLIKQDPTTCLVTIITRRPYDGRMVQRKWLNEDHVLAEMIRNYSQPGVYKHGTCTFQSVDFVHLSLAEQMQLMVESDVVIGMHGAGMVNVLWTRPETLVVEIFPKKRFRWGYRNLCQFVGCRWHQFRDGEDISTGKTANANDKIIPYDEWQRFFDPLFQGLLKGLEGRVDYELQQLRVAQHKPRRVMRPYWIAGAFMLGLMSVVLIYVFIVFRARRSFRPSLKTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG27</accession>
    <name>A0A8K1CG27_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG27"/>
    <dbReference type="OrthoDB" id="295029at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="612"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="739"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="82738" checksum="9337EEBB0A9F2809" modified="2022-08-03" version="1">MSLFAAMSDENSVWAKGSSLFNISSPLNDLLETDSFTLEQILQEDELIQEVKTRNTKLLEFLSQDQVVQKLVEYVVRTPEEGSDDLRALKYPYMSCEVICCDISSITETLACANDGKIVETLFEFLYQPTPLDPRLAGYFEKIMSMLMVRKPQEMTALMNKNTDKLLKGFVAHAQSFSIAELFKRLLQPYHNDYMDDMMDFPGMSLGFPPSNSWYGMGHDDDDASVGTPTSSTQKSLSWQQDKVVIDLLLANLTPTDTEGKPLDSDVHKHSADVLVDVIHCGTRAQQNDPASPASMSAPTSYALLEYLETKDVVEKILNLAVPPADATFVASSMTSALSVLSALLSRHTNARYSTTDELPATVASTLERLPQLCSTLRAEDHDAGTIRNQRYQTVPRLGLRRLKLVGLVVLLMQTKFQKVDAALLEQDAINICLDLFFKFESVNMLHADVESMIVGILESGGPDLLKGLIKNARLLERIVEAHEKNEEAVKQPKGFSYGFVGHLHRICNMIISLTEDVRGEGVEERQSLNDMTHADSVLEMLEEDKEVWKKWDELATKVLAPIYERERLPLGGSSNSVSGDDPYSVIGGFNPNEAILNEKFAEMLGSSAFDPQEDFDIKNSNDTPMLPDMHDSSSSSDEEEDRHGEKGEGWSNFEGGASWANFEHAANAFASSFDPNASFANFDDAPDSPPAVMEFVNDNEATSNVSSEGDAEETEASTGAEPVAEAAKPADEAEPAEEAAPTEAAKPAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG60</accession>
    <name>A0A8K1CG60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG60"/>
    <dbReference type="OrthoDB" id="155775at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538:SF1">
        <property type="entry name" value="VWFD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035430894" evidence="1">
        <location>
            <begin position="18"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="557" mass="60144" checksum="CE116A3B4035600E" modified="2022-08-03" version="1">MYFRLVGAIALTLGLHGAYNYHASHFAHPTRQLLEELTSAKGIHVTFTPRGASSSIPAGVAMHAVLYPRGAEGLQFDGRLSYQIHHEEHNYTLYDNKAYYTVEDTNAGRISRMACLSPNNVPPFHELAEALQNARVVDEVANADVTCDIHDSKLVEFQFAGEPYVFCSTPSTQSTDGVVDIHGQDLQASLRVLTETTEVSTLQPPASLDWSGCPEVGTSSASAQRSLLSSQSLDSAKQRVQDSVSVLTGGRRLSSMVDDECSCKGGLKKCLFVHGLGYTDGPTTDTFTEYFGNIHNQAKCCSSIQFLHLDTRDSTWYGDNLTSKLCDAASALSTGSDPQAIENVAIVAHSMGNLVFAGALMNKKCALADSSKWIALAGPMYGSASASKAVTTFDNLPPSLVENLCTENPYAIIEDPILKTLMFFGLCPTRTSLRSIVFKDSAPATPELKALMLEAGSTFKEHVSSSLCAVNAKGFASTDSIQLSTLGLISGHASFQNDGQVDFGSCHAEVSASKYQSSWNGGNFYLADINHLDATFRRGDGLWGESRKPVKWFNCQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGT1</accession>
    <name>A0A8K1CGT1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGT1"/>
    <dbReference type="OrthoDB" id="167797at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424350" evidence="3">
        <location>
            <begin position="19"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="552" mass="59022" checksum="9588B1A738223697" modified="2022-08-03" version="1">MRWTSLALALVASASVHAANIDEGFTQDGKTTYCEGVRGGDSAGAMSFPELYPHSVNRCPVVITMTASAVSVHAKDPIDVTWKAAGVKGEIPGNIFPNALDKTTKVPQNVLTSLMKACKAGTNCATLIDPTPTGPATAESGAFSAQGSKDLRANRFIFPDVGDYVLVGKIVLPGDATLNVSATEFIAFQKVSVVDPSVSLAPTTTPPATTTPAPTTATPASTTKGENENMSTPNTSKDSKGSENTTTRSEEEDDGFFATHGTLLIGVVAACLVVAVAGYVVVQRRKKAQQAAYMKRMGGPPMFAIGSSDGPDAGAYQHNKSGRHSITLPMMGRPSTSYTEEIPNDLSRRGSELDESFEEGTVDASNSVMASIESQEPAPLRKFSAQPYPPPHHQQQQQQQQDKYPQDSLYSDIRDSSMIQEESMSIRSDTSDMDRDYFQSEAWDATASAAPGHIREESTVNFDDEFETGRGYSMDSYSSEGVFDTARPGGRQSDASVDSYAFRPSSASVAESYKSRVSRYSGISDFNDSEIDSTRSSGISIFSARDTNARHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGW1</accession>
    <name>A0A8K1CGW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysophospholipid acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005628</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGW1"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="54833" checksum="F6F25AF9FD09C0ED" modified="2022-08-03" version="1">MDHIQALVTDLQPYADLVTPLKFEYLNAQVDDLSSSLGLASDQVRYVLCLFAAYPLAVVYKLLPAASLKHLFDIAVGISLAQFVLGSGWVHSFISSFLTYVLVKFGPPKFAPYVVFLFNMSYMSASHIYRLYVDYMGWTLDFTGPQMLLVIKLTSFAYNYFDGVVDKTGEKKDLSPARAKLYAARKKLAITELPSLLEFFGYVYSFSTFLAGPAFEIREYLDVTTGKKFIHDGKSKVPSSVLAAFSKLLVGSVCMGLFAQVGPQYPLSNLHDPKVAALPVGQQVLTLYITLIFCKAKYYSAWKIAEGSTVLAGFGFEGYTAEGKSRGWNGVSNMDIVGFEFAQSIRAASRAWNKGTQNWLERYVYTRTGNSLMATYFVSAFWHGFYPGYYIFFLSLPLATSVNRLAFKKIRPYFLEADGSSGLKKKVYDFVGMIATILCMHSFVMPFQSMSLEYSIATLKNTHFAGHITCAVLYIVFTLVPAPRAPKKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH79</accession>
    <name>A0A8K1CH79_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
            <ecNumber evidence="1">6.5.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH79"/>
    <dbReference type="OrthoDB" id="10249697at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118:SF1">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01288">
        <property type="entry name" value="UPF0027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="185" mass="19952" checksum="9A934FE6EEA6F3A5" modified="2022-08-03" version="1">MAKGDTKVVRSYEDELAFISQRDDLSCEIKVGMVDNMRVPGVFYANDKLRALVCDEVRDFSQAGGHGGFLPAAKQIANVAALPGIVKRSIALPDVHSGYGFAIGNVAAFDMDDPEAVVSPGGVGFDINCGVRLIRTNLHEDDLKDKRELLAQTLFDHIPVGVGSKGVIPMSFKVQQFFSLINGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHA1</accession>
    <name>A0A8K1CHA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_002472</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHA1"/>
    <dbReference type="OrthoDB" id="205060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031090">
        <property type="term" value="C:organelle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000051">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="463"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="224"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="228"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW63531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="579" mass="64666" checksum="C39C09CB22F9B045" modified="2022-08-03" version="1">MTDAKTAFLDAFDASLDGVFTISPPDAFMLQGLFLSAMVECSGPHEVAGILLQLHRRLDAVGPFTDSTLAEAEQQRWTWLLMELQLMVEIDAMRCDSRVAAEVTRLGQRIEAGNDTELTIRIDSAEVEMPLPEGTTIWDNVKRSFRDSTRLTLRRLASDESTSSADDRASGHVDHSSRRKRNRALSADDKVVPLLQRGSGSNVSDSMPSIFRSVTALMGMAIEETFLCQICYENNSLANSIELITCGHRFCIQCFKMYLEFKIVDGQVYPACFHEIGEVDDASGKRKACGARIEPSEIELLVNSEVWKKYLTFKFNKENQYGRQCPYCGYSQLCAGPEHPECICESCGKAYCFTHGNAHASSSCADYEMRQLESEKLNRSAIAKISKPCPGCKSNVEKSGGCNHMKCIVCETNFCWICGAVVDSAVAPTHFQWWNLRGCAGQQMDDVENQTERERFWWFVFRIAFFVILGPPAFVITLFFMVISCFFLPCMKVFDTSFVQVFTSFLTGVAMSLFMLLLGMAMLVAFVVGILFEALKAIVLGLSKCCCGWHHRTRGQRNEDKGTEHSALENGQERSAPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CID7</accession>
    <name>A0A8K1CID7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CID7"/>
    <dbReference type="OrthoDB" id="530303at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="64436" checksum="CAF5C203D0EDD2F2" modified="2022-08-03" version="1">MDMHDQRLRMTTCMARVHADIAALDHVLDLIDTCLDMSVYFNPPRAVMAGSIRLFDRVAKRVLASDADPALIMYWFAKAMETAASRDDLAMVRRVHYHHPTRLPVKIITKACERGNLELIRWVVDNRTDDVCVSDLSGELPAWRLDCCLKRASMTAIRCGHFHVLRWLYERGLIRNMDQSGDKAAADGDFEMVKWLHEINAPGLFTVSAMDKAASNGHLEIVRFLHENRQEGYTSTAMVGATVDGHQEVVNFLREIGAEEEVTWQLVHEAAHAGRLDILQWNNYAMRDRQWLQTAMTAAFNQGNLEVIQFLVERRRINCRPSHLETAATKGDLGILQWVHEKRCGEWSTTVMGNAARHGHLSIVQWLHNNRSEGCTTYAMDGAAREGHLEVVVWLHENRTEGCTATAMNESARNGHLDVVKWLHSNRTEGCTKAAMDGAAQNGHVTVLEWLHENRTEGCTTNAMDYAALYDHLEAVIWLHENRSEGCTKMAMDYGTEPVVRWLHFHRQEGATTRAMTRASRDGNLALLDFLYTHRTEGMAANAASMVEYDEGHLPINQWIRERYPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIK6</accession>
    <name>A0A8K1CIK6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIK6"/>
    <dbReference type="OrthoDB" id="168429at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="226" mass="25742" checksum="EEB3466AF88F38DD" modified="2022-08-03" version="1">MTTPYWTVHDVERFREQQRWRVRQQQLQSHLQAPAVASWASTSHESESRERPRKVSVLFRQDPKAFVPDALPPLAPELSDGCLMVESPMPHAAYAMFNAFDSAQSPELFAMGNPRPRISVGDNQENDGDDEDIAMMTGDDEDGASETARQRSLWRRRFLRQAELRKSPKLGQVALWDGVKVDLSMFTSKQLLDMPPRSAIQRVPHPFASSNDDEQLQQEELALRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIV1</accession>
    <name>A0A8K1CIV1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002204</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIV1"/>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.430:FF:000003">
        <property type="entry name" value="Checkpoint serine/threonine-protein kinase BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0137">Centromere</keyword>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="8">
        <location>
            <begin position="89"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="580"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="893" mass="102554" checksum="5EBF22D32DE5BDE1" modified="2022-08-03" version="1">MEALRGARKATDENGGVDVLSPTRMMRKRKVEVRDDNHQAQQPDFEWENSKENVMPLKRGRNVTDLNRALRTHESYQAKTNVETKAKEMEAEVKAYKGDDPLSAWVQYIRWIETNMPEDTRKKFGALEKSTRELKDITKYKNDIRYIRLWIQYADLVSNPKDIFKYLYQNKIGDHVSLFFVGWAWVLESMGNYAQANKVYLKATQKKAEPEELLSRKYKEFQRRMSRHWLKVNQTTDSNDDSMQRSALEDLSCDQADFERMGNSENFRRYARAQAEKMQRANAHKPVFTIYEDPVGTEVDTLDENADWKSLDTMQHQNKENDTAPTRWNGPLERPQHVEGEVPVAVASRRPVEPLQVFVDEEFSASDQKPSVVGKEHSLTLRQRLDGVSTEEEQLAQKPLKNFAAQKTESSKPPRAIKTKTGPEEKLVFDPALLKTTSGETLCFEELRARKYANKREETGHRHTHAKGLQPPLPKTKPAAKVDPLFALDTAAQEDMTINTRVAMEDVNNMFCSPGRDERASPPRSKKTWGVPEAEPVERKLHFSIFEDSMDSIAPHQDEVSQKHKLKKPIKIRLSKSISIQAVGFLGSGAFAQVFAVKAHGLDPSPSEMALKFEKTEGNLAWEMYIIYEIQKRLTEGGRVMPLIQLPILRRLDTFKNGSMLLMKKGNTGTLHDLLNAYRKNGRQFPETLAVYYSIRMLRAVELLHAADVLHGDIKPDNWLLVPGSFEQALSIGTMSKNTPHEATDLQLIDFGRAIDLRHFPHGTRFSGDCHVKGFKTVEMLTKRPWTYQIDTFGICATAHCMLFGEYMEVSKRTDENGKSRWGIVKSLKRYWDIGMWASLFHTFLNVGSCEKQPSLPMMRRRFESYFLDNPNKLEELRGLLVSQQTLLSRAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIZ8</accession>
    <name>A0A8K1CIZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Costars domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the costars family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIZ8"/>
    <dbReference type="OrthoDB" id="9871914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032970">
        <property type="term" value="P:regulation of actin filament-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1540">
        <property type="entry name" value="Costar domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044302">
        <property type="entry name" value="Costars"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027817">
        <property type="entry name" value="Costars_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038095">
        <property type="entry name" value="Costars_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334:SF1">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14705">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01283">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Costars" evidence="2">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="91" mass="10348" checksum="11AD74822D38324A" modified="2022-08-03" version="1">MFKGTARKATTKMDVDKEVEQLVVEIRRLGAQEGDKFGVTFGVLFDDERCQDVFEALMGTLRAAKRLKKIDYQGQLLLKGTHDKVFIELLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ57</accession>
    <name>A0A8K1CJ57_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ57"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="112" mass="12264" checksum="62153B9573056C74" modified="2022-08-03" version="1">MHHRIYSATKKHENTGATNKAALSAPSSHSLPVLHSKAQVFNTHQAPLQATNPVSTMGKKQQNKQQQQEQKPMPEKKGQAQQQQQQKQAAPAPAKEAPVQQEKKGGKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK54</accession>
    <name>A0A8K1CK54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK54"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="18"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="123" mass="13980" checksum="D60CF86EC37CF819" modified="2022-08-03" version="1">MSGREEQDNDEIREQDRFLPTANISRIMKVSLPSTAKIAKDGKETVQECVSEFISFITSEASDKCQQEKRKTINGDDIIWAMSTLGFDCYVEPLKLYLQKYRESVKVEKNDKKDNVGTFGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKC1</accession>
    <name>A0A8K1CKC1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKC1"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF123">
        <property type="entry name" value="OS04G0645500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="29522" checksum="897BA1D74D0929F3" modified="2022-08-03" version="1">MTSNGGDARHEAFQVLVEDHTDRLEETLRVKVYDRELELSLLLKEDELAPLFSGAAWAGTLLWDAAAHLTKRFLVKYRDKLARADNTMGVIELGAGIGVPGMAARIAGARHVVITEQDDLLELMHRNLADNASVLRIGDVFPEAKHGAIHARPLSWGTKETTAYLDKHADEPVDVILSCDCIYEPLYGKSWKELAETMELLCVKYPHALVMMCVERRNEDGIDKFLSFVETNTQLQWTLEEETIGTENNPLQLYYLRLPTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKF5</accession>
    <name>A0A8K1CKF5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxin-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014792</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKF5"/>
    <dbReference type="OrthoDB" id="78870at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="31717" checksum="1592E81A8AD3B682" modified="2022-08-03" version="1">MASTSTPPSMMGATGTTGTTAPPKPWERATGATASTATARPTTTAIGTGAATTMGTMSSTATGTPMSSLTSYPGSTYNNTNSVYGSAYGGTGYGGGYGSGYGSGYGGMGGYGGYGGGYSSYGGGYGGYGGYSRFGGGYGGGMMGGGMNGMMDPNGHMGWLTSFNQMVSSIGQITDMLGMNADALHFCITSFVNFFERIGGMFAGIAAMLSPRPQFPPGHPRHGEAQLTEEEEKSRVRRVRIFQFMLSLAAMGAMYKFARWLASLRRQRPALLAAAPAATARSLESIFRQTVGPTPRRPPTAAFSTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKF8</accession>
    <name>A0A8K1CKF8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKF8"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476094" description="Peptidase S1 domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="254"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="483" mass="52718" checksum="FACF86F29806E46A" modified="2022-08-03" version="1">MIKTSAFIVALLLFSWSLIAAIALASVPLVRISAEEDLQACVGVPIGPQHMLVLSTCLTGRVPMTKAWVMNLAMASSRNTSVQATLGPSIAVINITAIPPKQASAAQAVHVLALEKPLASSVPMAVLPLNMPYPGYLEVDRNTTLVSVDAASLKIVLTSEVIYISNSSCASVVCALPLQVKERHVRSQPSHWSFMLQLDSNHDAYRLLGVGGDRVTNEDGIWGFTRLPQAISAATLANHGVYGVNTVVSVNKEIVDGKIVETTSVYSEFVAGLRETENGETFCGGSLIAPTWVLTSAGCDSSSFNYVVIDTIDTEGKPTEAMKIKRKVKHPKYKDGHSFSFMLVELAHASSRKPIPYKADTFMLQLFDNMRVFSHVITTAFGYGYHLFNSKKMYLQLRSRKAPLLPAKDCPEYVRAKLDNSNVCLRKVTYGDYGGSVVANAWESRHRLVAVIGNGFDLEDRRAYGVAARVKVVYSWITQTIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKV0</accession>
    <name>A0A8K1CKV0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKV0"/>
    <dbReference type="OrthoDB" id="97693at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="157" mass="18013" checksum="B65F0B5A0A555574" modified="2022-08-03" version="1">MTAVQQWKSRVHRWHQLSRYYLNKWHYDGSKWAERVWYGTGSQTPNSVASVPFMITRNMRTQLEQMGFPGAEISSLLPKTAHELINQKTTYAQYVKMQQMAAKNEEIAQEVDTTEVKEIVAAIVAREEDEAAKNQATESTSSLALVPETQEEQAKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL78</accession>
    <name>A0A8K1CL78_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Indole-3-glycerol phosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_013010</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL78"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000024">
        <property type="entry name" value="Indole-3-glycerol phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0822">Tryptophan biosynthesis</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SANT" evidence="19">
        <location>
            <begin position="150"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="17">
        <location>
            <begin position="153"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="20">
        <location>
            <begin position="155"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="18">
        <location>
            <begin position="446"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="415"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="542"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW64388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1160" mass="126806" checksum="D17765F60F71C70F" modified="2022-08-03" version="1">MATGGRKSDARDAVQTTTATPHVKEEMNGSKDHVEGASNAGSAASGGGAVATKGVVKSKFCLNCQKDLTRTIRITCAECVHGKTAQPLIELCIECFGVGIELGGHKKTHKYTVSDCLAFPLVREHGAPVVDETTAVTNGAKDASSVVAVPSANEWTADEELLLLEAIEMFGMGNWKDIAEHVATKNEKKCETHYLGAYLSRTDLLPRFLDEPDSPDDVEMVDASVDLTSTSEQTTTTTTEASVLPERPSGSELAGYMPLRGDFDVEYENEAELILADMEFSEDDHPTERELKLKVIEIYNAKLDERARRKKFVVERGLLDYKKHQQSERRRPKDEREIIAQLRPFARFQSPKEHEEFVNGLITAMRLRKQILLLQEYRKNGVRTLAEAELYDVEKKKRETEQALQKQRESASYLYESARPYSGGRDRASRLASRGSEANGGDSVDDASRSRAAAFDIDGTPGSHLLTPKEKELCVKLKLLPKHYLVIKDALVRECYRLGYLTEQTAKDIVKIDVNKTGQIYEFFVNCGWVRKEASLTTVAVPTAKPAPSSTEAASTATDPASSASPSASTGSPLTPAKRKADELTPSASISTVEELMSILDEITAQRRVDVAHAKQQVAPDALRTQIQTTEAQFGPALDVIQRLNAPAPNGWSQLALAAEFKRASPSKGDIAVYLRLEDQAHMYASAGASMISVLTEPKWFKGSLEDMQTARATVETVQNRPAILRKDFIIDEYQLLEARAYGADCVLLIVAILTPEDLTKLIKATLALGMTPLVEVNSVEELHIAIDADARLIGVNNRDLRTFKLDLDTTVRIADAIRAKGIALGPQGVSLLALSGIHTRADVIKFEQCGAQGILVGESLMKSGDVKVMIRKLMEARRHSGEINELFPQPLAKICGITKVEYAEAALRSGANLIGLIFVEHSPRYLEIEQAKKIVDAVRAYGERTERILPKFLEIKGVESTLNVCEWYQRNASALRDACARTPLVVGVFANKSAAEINEIADKVGLDIVQLHGDEGFEICREINVPTVRVFHLPDHMNSDSVDAEGIFQHVKPGLANFLLLDTTVKGQQGGTGMTFDWKIAALFNQARLPCLMAGGLTAENVGKAIAIAQPLGVDVSSGVEVKGSPGVKDLDRVARFLKTVKDHLAVASLKIDEGDEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLE4</accession>
    <name>A0A8K1CLE4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLE4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445979" evidence="1">
        <location>
            <begin position="24"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="300" mass="32930" checksum="472BCAF333F51287" modified="2022-08-03" version="1">MPPGRFHALLVALVLWCSCGAHAQFLRTKELVMTDLQIVHGATEAEAKAQCVQLALERKANWLVTGQNLNTTRGGDAAVRSGVNTTEDEGDDAFVLLCMRQDSVESVRNDPPDLFVVQSVDVLAEDACPSAMVEFYQPRNGVVTCLKLVPTFIALGSGLYVSDMTTVQSLMDRSEILGWSTLDTSIQTNGRVTTSNTTSNEPVSVFLAFKRPVRRVRNVKVRSNIHRKNHVKACRTKYGETWEEAGPGFLVEDDDRITILCVERGPSPISFERVLVNVSVATSTVGCPRGFEDPLELSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLV5</accession>
    <name>A0A8K1CLV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLV5"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="192"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="47947" checksum="F931E8DF0396B900" modified="2022-08-03" version="1">MTRPNKADQENVFTSKSPLLSPGPVGLNYNSDSAVYEIEHQRSYRHEESDEDEARDFFEYETPSFANPGSMKKSMSSNALIPRASWRGFRRSSLPEDRQVNPSTRRARLRTMKKHLKEPRSSQKHRVSVYCTCDQLQLFKLLKNLEQRKSSDLNSLGWKHKMYMGAIHSTCAPPVEDSNGDIISLPYQQKDVFYFGTGCTVFWGLTRAEEQAHLRTLTTFSVGPVKQVEVEDMDYTYGESSHIFNDSITLESNRASEKLAISFAMAQSAKLDVFEERVEETIQKTKHIPQNLATTGSIQYSQSDISKLIGQLFIVRNDVNLNSDMLDEPEFFWEDDEYQPLYKKMTKYLDVDNRVQILNTRLDILRELLDVLNQQLAHRHGTKLEWIVIWLIVAEVLVDVVWNMLIKDILGFFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM14</accession>
    <name>A0A8K1CM14_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM14"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="11952" checksum="FF655B725BED3904" modified="2022-08-03" version="1">MALTSHPGCSSTNILVEPTTNNYFWSRLKWQIISIMPINQSAAMGALPSLYAATAPGAKSGEFYGPGGFMSIRGYPALHDPSKESKSAETARKLWEVSERVTKVSFPISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN09</accession>
    <name>A0A8K1CN09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN09"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000026">
        <property type="entry name" value="TBC (Tre-2/Bub2/Cdc16) domain family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="165"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="484" mass="53777" checksum="BB578091223DA447" modified="2022-08-03" version="1">MSPTQRASSNGSSSDGESDRASRSSVERSTGDEALGRVKISLSLLQKPAAHGTRVTDAWYMLKGVKSGEVLYEPSDNDTIETVTAEAERLLDEEIYNQEMEDFYGFRVPPSGTSTWAHLRSYFDCREQRRIAEWEDAFDSQFFSVMSCRPPGSDYATVQRMARRGIPRHWRQRVYMAMSGATEKKESEASDYYASLVAQLASRDSVSFRQIELDIDRTFGHSHTKIATEAGRSVLRRVLKTYSMRNPAVGYCQGLNFIVGFLTLGVDEETAFWLLAVICEDLFPGYYIPTMADTQTDMLVIKQLIAEELPELDEFTSDVGLRRGCWLRIRSLLDIMLHAVLPSLPQLEGVAMAVLVFFGVDHVAEPHILSNALAAAFFGIEMGVVTVIWASSSFPSCFSVNEHSVSVMLAVVSGSSSSASPPASLFGLFILSLARTRVKLALDPAPVEWIQTKYTKLSREMRVTIETAMVFFAVGLRHAATDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNH6</accession>
    <name>A0A8K1CNH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNH6"/>
    <dbReference type="OrthoDB" id="113054at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22123" checksum="4780FBEEE811CEA9" modified="2022-08-03" version="1">MPSHRSVSVATTPSLPVLETVAVRPSRRNPSVSSSLRDIDTILVRDSIKRDGDRYYRVDVYLNHPHSLVGGEKRPSGQVQHRFSAFVDLRHEIHFHAHWSHARSVPCQFCLKVMEFTTVSRFQPSLLTKVLVNDEGKCRLLSQFMQDLMTLVVEAESNLQGSEACRAQHFIPQLVQRFLRPADVTDTTASAETTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNK6</accession>
    <name>A0A8K1CNK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_003671</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNK6"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 12" id="KW-0288">FMN</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="13">
        <location>
            <begin position="372"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW65906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="54881" checksum="2DA9B913A591C3F9" modified="2022-08-03" version="1">MKTVTRLARSVQQGAVREFRTSAAVANAATDGPAMTRVYGGLKDEDRIFTNVYGEDTWRIEGALRRGDWHRTKDILCMGPEWIIQEIKDSGLRGRGGAGFPSGLKWSFMPKQTDGRPSFLVVNADESEPGTCKDREIMRKDPHKLVEGCLTAGFAMRARAAYIYIRGEFFNEALILQEAIHEAYQKGFLGKNACGSGYDFDVYLHRGAGAYICGEETALIESLEGRQGKPRLKPPFPANTGLYGCPTTVTNVETVAVSPTILRRGASWFSSLGRKNNHGTKLFCISGHVNNPCTVEEEMSIPLRELIERHCGGVRGGWENLQACIPGGSSVPVLDEELCQDIMMDFDDLKQRGGSGLGTAAVTIFDKSVDMVAAIRRLSHFYQHESCGQCTPCREGTGWLESMLKRMEKGEADLEEIPMLEEVSRQIEGHSICALGDAAAWPVQGLIRKFKHKIVERIEDPASFNPEDHFQKSWPGAPFQNQEWVSKFGDGSAYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPC6</accession>
    <name>A0A8K1CPC6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPC6"/>
    <dbReference type="OrthoDB" id="198232at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453360" evidence="1">
        <location>
            <begin position="22"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="26891" checksum="3508B1A6A39F365E" modified="2022-08-03" version="1">MSIMTRSSWLWLASCALLSYASYESAYALSADRVPPSLPRQFQADLLIVSHLTNPQQHYPHSRREIRIQYDYDQGIARADMLKGYEVGKTYVRRYDQKCEYMVKQGKYRKCERAYLGDVMPTPEIPFEQQFIGVEMVRGKPCEHWVHSYATTRVHIYADERSKVPLRLTEEVMVANEPTLMLTYDLRNVRLGPQNITNFQVPGGYTHKECTRNVDGFPYIHAFHYYLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPP7</accession>
    <name>A0A8K1CPP7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPP7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="83" mass="9575" checksum="74EA932572420306" modified="2022-08-03" version="1">MTETDDKTMTLLLVAFCQAVVFVLFPDKFSPSDPLSIITYLVSQAIFLRYAYKYHVVETPEQALLLQLFVLNPIYSYVHDHAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPT2</accession>
    <name>A0A8K1CPT2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Anoctamin dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPT2"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032394">
        <property type="entry name" value="Anoct_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16178">
        <property type="entry name" value="Anoct_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin dimerisation" evidence="9">
        <location>
            <begin position="41"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="8">
        <location>
            <begin position="238"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="724" mass="83932" checksum="05F1E5A44A5D5609" modified="2022-08-03" version="1">MARKRVSAATRRAAVLMADKKRSKMLKHGYGTVDIPTEHWDYVMVFPDPPKEDVEPHLTRESIIMKLRAVGLETKLFYSSGKEMVFCKVRAPEERLKDEAERMKLRLLLDADELKHTADKGLPEYGIKPFPIRDIKQTYPYGPYQFIYAPYIQAPDAQRFFHRKGPSGSLFSSTERMQIIEHIIINHTNGAGCDLEQMLYDGIIIECYPLHDEEVKMDLKKKWIVWNTSPMEQPFEEIWEYFGVKVSLYFLFLGHCTKWLTYPAIIGIVPAVLNYVVSDAYTTEVFTYISPAFGAFMTVWMNAYLEHWKRVNARASLRWGTTDFEEIDMLRPQFKGESIPSPIDGSTTRWFSDREKLKRVAFSWLIISFLCLIVFAVVAAIFYLRWDLTKGHDAEALTIYNFKLGAMVAAFANVVQITVMGKIYNYIAIYLVDQENHRTDVEYENSLIIKTVIFQFVNNYAALFYVAFIKEGVEGCATTCMWELQYTYATVYLSRLFTSNMSEVAIPRLWVYINKYRLTGSIREEVVELAAEMSHAEKELFMASYDWRGTFDDYTEMVIQFGFTTMFVVAFPLSPLLSYLNNYFEIRLDAYRLIFESRRPRPQKVKDIGYWYQVLQAFTAISICTNGGVVIFTGDYFNGVSTAMRVWFFTLFISSMFFLKYLLEAVIYDVPRGVKAQLRRQDFLVGKVLYHVPDEDLTPAPEVLKSDLENPQAALAIADHDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ05</accession>
    <name>A0A8K1CQ05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasomal ubiquitin receptor ADRM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ05"/>
    <dbReference type="OrthoDB" id="340431at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13314">
        <property type="entry name" value="PH_Rpn13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.70:FF:000001">
        <property type="entry name" value="Proteasomal ubiquitin receptor ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.70">
        <property type="entry name" value="Proteasomal ubiquitin receptor Rpn13/ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044867">
        <property type="entry name" value="DEUBAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006773">
        <property type="entry name" value="Rpn13/ADRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044868">
        <property type="entry name" value="Rpn13/ADRM1_Pru"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038633">
        <property type="entry name" value="Rpn13/ADRM1_Pru_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032368">
        <property type="entry name" value="RPN13_DEUBAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038108">
        <property type="entry name" value="RPN13_DEUBAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225">
        <property type="entry name" value="ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225:SF0">
        <property type="entry name" value="PROTEASOMAL UBIQUITIN RECEPTOR ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04683">
        <property type="entry name" value="Rpn13_ADRM1_Pru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16550">
        <property type="entry name" value="RPN13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51916">
        <property type="entry name" value="DEUBAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51917">
        <property type="entry name" value="PRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pru" evidence="8">
        <location>
            <begin position="18"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DEUBAD" evidence="7">
        <location>
            <begin position="338"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="47617" checksum="73297FBA85C89ABA" modified="2022-08-03" version="1">MQSLFPQYGNVFGGNNSNGRNELVSFNAGKMTVQPTANGKFLVTPDLKKGKVCLTRGDDQLLHFQWVDRQTGASPDDFIIFPDDATFTKASTGREGDRVYLLQYKNSSRRFFFWMQHKDSSRDEELANKLNDFMNNASASAGGSESSRGGAAGNVQLDHNAIMQMLGAMGAGDRGAAGAGAPGAAGVQISDLQNILQNMGLPTTQAASPATSAASSSQASHGASSAAATTASTHHDDVSGMEVDDMTEEELLRLAIEESMRDVQPDSGAAQPPAPSAPSPAPTPTPTGASNVAPAPAPVPFPSTTPAAPAAPAPAAPAPSTGSITAADLQRAMASIQAFAQPKSVSLMKLLSAVNVTTLLQDENAISALLPHLPEGAQTPHELQATLRSPQFRQSVASLASALQTGNFNAVLTNFGLDPTAGAAKLTYGDSIGAFLDAIQHWANQQDTSMTEEEPKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ61</accession>
    <name>A0A8K1CQ61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="16">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_012320</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="16"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ61"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000113">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="19" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035481409" description="glucan 1,3-beta-glucosidase" evidence="19">
        <location>
            <begin position="20"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="20">
        <location>
            <begin position="43"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="190"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW67204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="737" mass="79356" checksum="00EA4BB16A1E9FA1" modified="2022-08-03" version="1">MVQIGSAVLALGLLGLVEANKFNHAPHRNGTHGHHHRQLVATCSLEAAGIDYVGNDIGSVIAGAASECCAKCSAVSGCRAFSWNDYNGGTCWLKSGKGATITTSGVQSGTVAQNTDDGKCTLLANLDYSGNDAGSATSASAGDCCSKCAARSGCKAYTWTPWNGGTCWFKSAVGNLAGYAGAYAGVVNPTNTPSPTPTTPAPTTPAPTTPAPTTRTPAPTPTTKPPSPGKCNVEQDVDYSGADVKSVKGSAGDCCEACSLTNGCGAYTWTDFEGGTCWLKRSKGAANANSGAVSGVLPQEDRCTLEQGVDYIGLDVGSANSESADGCCSLCSSRSGCGAFTWSSGVCYFKSHRGQTKANADVVSGVVTVANRPQTHVQYRIRSGEIPAKSVNLGSWLVGESWISFTSPAWVDSWSVAGQGEYAAMRLLGKDKGTRQFQQHWATWITENDIAEIAGSGLNCVRVPVGYWIVNDDPTTQTSADSEVFARGGLAYLDKLVNEWAVKYNIAVMLSLHAHQGSQNGYDHSAPKNVGVTSWSKSQANVESSLQLATYLAQRYVNSPAFLGMNMMNEPAGDTDQGVLENYYLEAYRRIRALGSDCILVTSPHLNLQGPPIMMNFMRYPQYYNVWHEFHIYYAWRDGLNADQILAEARTYRQNHLDNWSGNYMHIGEWSLTVPPSASGFNDRNKLRQLAETQMDQFRGAHGGWSFWTWRHDEETKQLSGWSMRQQLRERVFTVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQD5</accession>
    <name>A0A8K1CQD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQD5"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="37"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32146" checksum="97C862D02426DDEA" modified="2022-08-03" version="1">MASSSPVCARTRQPAVFIPHGGGPRVILGHPGYAELVTWLKAFRKTYLKTTPDAIVIITAHWEENVPTITSAAHPTMLYDYSGFAPEAYQIQYPAPGHPQLAHRIKSLLAEYGLPAKLDSTRGNDHGTFIPMKLMFPEAEVPTVQMSLYDTLDPEQHIKMGEALSSLRDDNILIIGSGLSFHSFKHFFGNKVKANRVSEPFHEFLVDALVHTTDPSERRKKMNQWLQAPYAREVHPREEHLMPLFVATGAGLHEPCQEIYSGLVMDIRTSGFLFGGESTSVPTTVDPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQK8</accession>
    <name>A0A8K1CQK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQK8"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="37"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="659"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="427"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="590"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="659"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="161"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="725" mass="80896" checksum="4DBA837C2D4A6298" modified="2022-08-03" version="1">MSESKRVKTLPGAVSVNTSGATVISSSLPNAASRAERVKVFCRVRPLLQRERDGWSYDDFCEHEQGTNQDDTSVHDDEPVTGRSSSTFLTEKGKIPLDASVLTIAWDGKAITHHGSSETKDFAFDASLSEHTTQEDVYQRVAYDVVQDVLDGYNGTILAYGQTSTGKTHTMLGHDDGLEGDGRGLIPRAFEDIFARAESARARCKTTIALSYVQIYCERVLDLLRPETPSSSILIREDAERGVYLDGAAWCGVSSVEDCVRLIMRGNANRAVASTEMNAHSSRSHAILIARVERKECLGAQEATATSTHRVKLSHLYFVDLAGSERVKKSKVYGRHVHELKAINLSLSALGNCISALSRQQPQRHVPYRDSKLTRLLQSSLGGNAKTSLIITVSPSPTEAHETLSTMQFGQRAMKVAVQAHQNVLSVLDYKALYEETQQRLDEQQQVQQHTENELSKLQTSKQHLEDQLVKAQLRIQHLEFECQAVKVAPTTSTTAASASDEQVQALIKQHEADLAHIQAKCDLQVATYKRLAEEAQQEWHELEDSLAQEKQQVLSCLQELKEFKMRFFQLEEETTERIAELVQDGRDHEREYTETRDTLQQRVKAQEQELEAMKKKLAGTEERIQQLQDQMELDFVPKQAIKQMESLYESAISKLQTRVGSLEQRSSSRKLQTNQERDDPPVDPRKGSNANNGGLPAIAPAPPVHKAIPKIGRIVPGARANSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQU0</accession>
    <name>A0A8K1CQU0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012150</name>
        <name evidence="3" type="ORF">Poli38472_012156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQU0"/>
    <dbReference type="OrthoDB" id="159229at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036433882" evidence="1">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="234" mass="25781" checksum="81852DEA3EE0407C" modified="2022-08-03" version="1">MKLFASAVVAASVAQLASAQTILYNFEPELTAGVNGVALVEYQEFNSTKANIFLNFDFSGVDQGAIRKSDGNCTSDVVQYKWHIHVNWNSLNGSESFNWCSKALTGNHYDPLKACGPNSEFVDTPECAPRVKDYACNPDNYAKNPLACEKGDLSGKFGDIKLTKDKTFSAQYTDVHYPLFSENTPQWNMILHASCGKATPRIACAVGRQVFLTDDYWGSSDSSDSDDYNTPYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRA7</accession>
    <name>A0A8K1CRA7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007491</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRA7"/>
    <dbReference type="OrthoDB" id="59153at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="START" evidence="7">
        <location>
            <begin position="151"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="281"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="52077" checksum="C596C4410D4C5C3D" modified="2022-08-03" version="1">MSMRGFFRRGSSKRTELSAMSSGASTSSQSPISSDLPPLAEEQKETFIHEARDAYIDLFHSIEIAQAKTSSGGTHLEGVSEETGSTVWMCTTTTLYGKLEEVAELYLSSDCHFILDFSQSKRLYELEWPSETHPLRCTALRWSKWTAIANVIKDRDFVRLEYMDSFEDQSTGHRGWARATKSVELASCPPSQEPNGPRRGELFVSGKIIRETDHPGMLEFTTLIHLDVKRAVPAWVRKSVLKTRKINALNMNHLLKIRRLLKVKSSVANQQLWSHRETFKQVDQRTCHGCHEHISRWNRMYTCRDCSEVICPQCAAISYYDPMFHQLKNRICIDCSVVDPEQSILGAARELEQRQKAQEFNLSPYSIDDDWRDHALSSFSQGSDDWNAVQNELTVSRTDRHAYGSNVISFSQAFAHLPSKPWVKPRTKPASASTSQERSTFDLSHLQHYAAPKQSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC9</accession>
    <name>A0A8K1CRC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC9"/>
    <dbReference type="OrthoDB" id="93881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035433872" description="Ubiquitin-like domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="41920" checksum="1D46AD0EF4EB3618" modified="2022-08-03" version="1">MVVKLFCAVVGVGSVFSVDIDISKTVDDLKDKIKEKQGYGFPASELKLYLARDGDTWLNSRDADMKALKRGEIPDRIKSLMQEHLLLDEAWDLSDEAYFGKSFERVKGDIHVLVKLPEEPDQAAGDRPSPSASIHSENRRKRWRELNDILDKNKKAKTNGDDSTSTGYSYVRWGQVKSVLGFERYKQERKPIPDDTFKFLVDYLKYASDAMNGYTDASREAKRYHFIAPVLIMLCSLFDDVKLEVEETVDGNEVHADGHFEFVLTRGKKKICIVEAKKNDFDQGRAQALVGCEAVADREGLQVVYGIVTDFMKWHLYRSGENSILMDSSTLSAKSDELEVDSLRDVCEMIYGALLDHEEECKKENLSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRI3</accession>
    <name>A0A8K1CRI3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007887</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRI3"/>
    <dbReference type="OrthoDB" id="7464992at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07331">
        <property type="entry name" value="M48C_Oma1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="8">
        <location>
            <begin position="82"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32872" checksum="88A96C5F938E199F" modified="2022-08-03" version="1">MARRLTWREEWRTTPPYLRALMLGTASVGGLYVASHVETMPLTGRRRVMFLSHLSEERLGERAAQEIMHSERILPASHPMSRAVSRIGHKIAEQSDNPHMKWQFHVIESHEPNAFCLPGGKVFVNTGLFKILHNEDALAAVLFHEAAHGLARHGAEKISFSLLVYGLLAFFLPDYGQFSDLLVKLAVDLPFSRKLELEADSIGLRLMAKACYDPRASIHMNNALGKIEKKNPAARFKYFSTHPPSKERVQALRDQLRDAMEIYEASDCYDRKQAFHTVFVPEIVKPDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRX0</accession>
    <name>A0A8K1CRX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phospholipase D</fullName>
            <ecNumber evidence="2">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012324</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRX0"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09104">
        <property type="entry name" value="PLDc_vPLD1_2_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09105">
        <property type="entry name" value="PLDc_vPLD1_2_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="212"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="443"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="64198" checksum="91F929B3FAE3FB25" modified="2022-08-03" version="1">MVSTDVVAVRTGITCTKLKNPLSMATKQCVCSPCHLCEYSLSKMKCQLIKDDGLVLSDGSELTLQQPVLQPTEWFLTKEEITQSRGGVPRSNLQTYSKGNKVVVFPSSDQYFLFAYRDIERSGANDTVYLAGWGVDNVPFDPINDPTGKKSSFQSIMKRAVQRGADFRALVWANQLEREQNLVMRDFINTNLTKPTVSGPARFVFDDRVPYLASSHHQKSLILRQQNKLVAYLGGVDLTTDRWDTINHDQSKLRDQVKISRYFNGWVDAHYRIEGPAALDVGNNFLQRWNSAFKPTLGKIDDLLDFENPGHSALPPLSSNGPLDLNGKGPHMVQITRTFSCKYKHYEEFAPRGENSLFQARIKAIKAAKNFIYIEDQYFVLVPELLDALLEVLPRIQRLIVVAQRVMPDTKVTGYDRYSFDMVAPIQKRFPNKFQLYTTKEAKNLYIHSKVVIVDDVYLSIGSSNWNRRSMTSDSEIGANVVDTETVETPEGLQVGKLVRNFRLSKFMEMTGKSVASLAKMKLIDAANAFDTAAEDPASIIERLQVEDSVKFVAFGDVVRQKIDPDDKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSP5</accession>
    <name>A0A8K1CSP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein WDR12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR12/YTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSP5"/>
    <dbReference type="OrthoDB" id="10251381at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03029">
        <property type="entry name" value="WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028599">
        <property type="entry name" value="WDR12/Ytm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="9">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="257"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="345"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="424" mass="46782" checksum="1B914AC3E37E823F" modified="2022-08-03" version="1">MDSEGPQVRVKFVTKNAAIRVTETPFAVPTRLNRQGLSQVVNHLLNTTTPRPFDFLIDGVFLRTSLDKYMQRNAVSEESLLILEYVEALPEPEQKNETNHPDWVSAVSVAKDVIVTGCYDGQVRVYDLKGECLASVKAHQGAVKAVSVQFIQGKEYRITSSGKDQMGQVWRFNASSKQLSAVAALTGHLNSVDTIQLHSGGRQALTGSWDNTVRVWHLPEDDNAGEDDEAQPKKKQKNSAKSSGTVSFRQVEAEIILTGHTSYVTGVAFHPTQEDYVVSGASDRTVRFWDLTTHLCKQTLTGNRAITDISVNANGLVLTAHPDNCVRLWDPRASQSGENIVQKTFQSHTEWVSAVEWHQQNENLFASCGYDGAVKVWDVRSTVPIHTIAAHEGKALDVAWRPVSEPAVAFVSGGEDKQLKVYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSS8</accession>
    <name>A0A8K1CSS8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSS8"/>
    <dbReference type="OrthoDB" id="168273at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="18531" checksum="57A67CF4CB57F7E9" modified="2022-08-03" version="1">MSSPTNSQADQSDNICKYSSKPCFNERAFKKTGELHSFCEFHRAMANRNQRRCEQKRRNQRRLERMQALSQQQMQQADYTMLAPKFSMTQLHASPLTVHGDGVFLGGNPLEMYGNFQGSFDDYDVEMLDDCDLEPYEHPVSLHAEDLEYLFMTVMDRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT63</accession>
    <name>A0A8K1CT63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S26 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT63"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="8">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="8">
        <location>
            <begin position="102"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18795" checksum="621B200BE20C7B5F" modified="2022-08-03" version="1">MWGEVATVATYFVRFAGTAYCLLQGVDTIKCVGPSMLPTFNRDGDIVLVDKITPRLRTYERGEVVIAKSVSNPRHTVCKRIIAKEGDTVCVRPRSSSSEVEFHKIPKGHVWLEGDNKHDSHDSRYYGPVPYALLQGRVVMRIWPLNKIALVEKRFATQAFRERSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU16</accession>
    <name>A0A8K1CU16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="14">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_006074</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU16"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 14 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="777"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="269"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="333"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="543"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="297"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW68606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="830" mass="94214" checksum="5A0CC20BCA8A99F8" modified="2022-08-03" version="1">MAEARSPHSNGSTSAKKRREVALGGGSPVKKLKLDDDEPPVANPNSLEAVRDRNKAMGLDLLEKNRRIAFLTQKCESLFQRNAVTKSAFRCIQRQWLQLLDDVHTLTQTLGDSTENEWKAVVEHMDTLGVLRISPAIVKLELPEWFVAISNGEETVELPNKPETEHDVVETSVILTEKEKAIEVSLQEEHERVKTTLQKLLERMPQVQATADVKQIVKEKCDSTAEALRLKDELEAMKEKIAELQADLEHKEAERHRACRNYDRLSQYVERQREQSAPSDVKSEQPAANGSNDSADEEKPRATRPGEKRVTLQDATDRAPADRETEKKLRADLQIFNQKLQTERATVNNLRREIEQLRAAETAWQKVEAQLKQEYEDKIVRLQEESTLTAEELSKVRHKSKEIEQHVHEKWKKKLDKMQADVIKAKTQMDEITVKNAALREKLSSYTVYRDQVGDLKSQHESLKRENGNLKKQVENVLAKADRAQAAADNQEIATLRAQLTTSTQQSEELKKIVDELRAIESKSADAKLSGAVKREEETQAKYTSLQAQHAEAVADLEKARIELEDLKATQDAFREENDALVAEIESVGKEVEAARHSKKKVIHQLEEKRNSAKKLQSQLAKESDAKAHCFEELAAARLQVSSLSHVHKQQKATLDAAKEALKARETELDDLKKYVKQLEIERDVVANEKLKVQREADIAKQLYNSEASQKQQQQILQDKKRSCEHCESHRKKAAELEKRLAATKAASGSGGAGGEGGSLSELERFELVDLQKQLKCSVCQDRHKDVIISKCFHMFCKECVDNNLKSRNRKCPTCKKMFGQDDVKNVWFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU91</accession>
    <name>A0A8K1CU91_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU91"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="163"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="163"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="166"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="41105" checksum="58B07C3DC344A3F5" modified="2022-08-03" version="1">MNLEISTSNPPAHAAEYSNEYQATGPALPRLEGGMLSSALPQPSIMLKKENEPWRGSSGFGIANILNRNNNGVAPPLPKFSLPSLHSFGKPLMTKTDQSMNRPRSILHDTPMANDSHRSHSPNPSQSSPTSSTKETPRKVVPSRRIAPAPADDDDNDQEDQSMDSIRGGRWSADEHERFLAGFRIHGHKWKRVQQVVRTRSVTQVRTHAQKYLLKLAKMKAEKKGGDEDHAGSVNNSSDVEMSHAASSRVEESDEQSPRKKQRRYEPADQLDEEYIAAAATTLCFLMRQKIDSIFDTRYEDEKDLEPYDCYSAESSYGSEANAAEHSRKRPFMHFITNESADYSYNEHHQTQESNNFSLEGKQLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAK2</accession>
    <name>A0A8K1FAK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AGC protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAK2"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000465">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="607"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="879"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="522"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="567"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="636"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="945" mass="104847" checksum="AFE251274AB3826F" modified="2022-08-03" version="1">MERRSFLKAEGAARPKHFFHGIDLSTQPHLTKSGRKSKRVVKRVFVILDGYLFYFQNALATEPCGVLPLDQSQYLLHSYASSERLSNFCVEIHSPVRTWGSIILHFHKCESTKVHEIERILVTAGASRRRQLPRAKGTAARSLSPDRRVSRLVTLRRLLSSPRLTTHAKLKDTRVEELSTPPSGEDQSMQLETDEAAASETTSFICKTTMGRRRSLIKMKLGRAAPTPDYSSETTETIKPNSTISFTSRQTLRFDLEDGDFVAEDEIAVELCHELCTNGFVENAGRKVFHFMTPFWPWERQRRTGDQFLLTMGSGTQPRVRFATSLDTAATTRTTAKANGTIEISTAKGNMVAKIHLGKERAVSFPIVLATEAARLRPLLQQQRTQPLVICAQHPSSITPPHTVAVRPPSPQRITHGSVYLSSGHVQTSTTLITAGSAQLEITFESSLDPPPPIPGSLSPSKCFPLQITSSSAKTASAQPSPVSSRPRALPLLLPLPIHNEACFALDASEIAPPSSIARSPVVSDLRRRMTTSSPSPSRFSQQATAASPLKTDSLAQATVSSPVRGPMGPSSPTSPSASHEAPKDLHLVQAASLAESYSGSCQLKKYEPIKMIGCGGFGHVMVARHRATDQLVAIKTLSKKAIATQHQIQHSLSEKAVLTLCRHHPFIIQMHAAFQTIDHLHMVLDYCPGGELFFHLSRVGRFREHQAAFYVAEVFLALEFLHNNNIIYRDLKPENILLDKHGHVRLADFGLSKLGIDDWTLAMTFCGSIEYLAPEVLALGEPTFAASLPRKGYGKAADFWALGCLLYELLTGEPPFFSGNNRPRLYARIMKGQLQFPAFVSADARDLIQGLLTVDPTERLGSRKRGHAAIKEHAFFSKYINWHALFHRGLRPPFQPRADDFANFDTQFTSMPLSVVDKMTQFPRQIPMDYQLFEDYNWEANTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAZ4</accession>
    <name>A0A8K1FAZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAZ4"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="188" mass="21510" checksum="936B3CA6D0C5132C" modified="2022-08-03" version="1">MTAEATHTAPHVDKSSVSIEIRSYQPEDLDQVRKMFITGMSKYAEVEGQSEEFWADYVKESLETDLSDIQGTYFESGGHYWVATTIVDKSEVIVGMVGLEGKPNQEGELRRMSVKPEYRRFGVGRILVSHLEKWSRANNVCKIWLTAADAAQQACRFYESLGFSFVQSKPYPAENPYFQVLEYEKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBM8</accession>
    <name>A0A8K1FBM8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBM8"/>
    <dbReference type="OrthoDB" id="427735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475739" description="AB hydrolase-1 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW54989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="60605" checksum="42425F99896C8544" modified="2022-08-03" version="1">MRVFRPFTFALGAVFASVSASAESLLADWAPCGSKFIVSFECSVATLPLCHKGVCDSDKTVEVQVKRVAGTKTASKAVWVLTGGADASSSKVEGSLDSLARALDGQADVYTMDIRGTGNSTLLGCKATDKYTTGAAVDFRVVADCAKDIYAQMDEQPASFSVTSAAKDVVSLIGEHKGDVFVYGSGIGSYLAARVMHMAPDNVKGYVLDRVVSEKRGNFAYAGSNRQQAATELAALCDKSPDCRKNYGESLSEDLRMKDIWNNLATKYDEAKSDPKYAECTKLLCGDCKDVSPSDMVRKLLEMGVPASSTATREEIPDVMETLWNCDDVKVLQKRMGGEGSFAEMLKEFQAEQETATADPAKEGPAEFFTQLIKHSEIWAHPSRSWEDAKKSIQSTTFGAYQTYDYAWHCVLSGNMTDPSCSALKEYGEQLSKPIDFSTIKDMQSLLYAPDDYYSKFATIPDGSSALLMTSKLDFEMPASWAKEQMSEMRGDSIQLIEFETNAHGSEFINTTPEDHNDCGTDILASYVLGGGDLDQIDMSCFDKFQPIDFKDMQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCH8</accession>
    <name>A0A8K1FCH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCH8"/>
    <dbReference type="OrthoDB" id="434648at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052032">
        <property type="entry name" value="ATP-dep_AA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040570">
        <property type="entry name" value="LAL_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005543">
        <property type="entry name" value="PRK07206.1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585:SF2">
        <property type="entry name" value="ATP-GRASP ENZYME FSQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585">
        <property type="entry name" value="FUMIPYRROLE BIOSYNTHESIS PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13535">
        <property type="entry name" value="ATP-grasp_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18603">
        <property type="entry name" value="LAL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="248"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="700"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1005" mass="110925" checksum="76CF6242FBB0AEAB" modified="2022-08-03" version="1">MGNTPTTEASTAETTSSTPAMMHEFKPLSPEQRAATFDERVHLPVSSRRVTIASTQPMSGFRPLQRAATYDPRLRTQKHLLTASDVMYRRYFNMREKRDVSVDARRPLYRIPEGVEEAKKHKGDAIVVVDPFSTGLTLSQKVLERGYECICLHSDTLEVMKDLIKHIPQEVSDQFRAVVCHNGGHEDAEQAVEETLVALKAVQGVRIIGVLAGAETGVMLADRLSERLGLTTNHSSGSDARRNKYLMGEKVRRAGLRAVKQRSVTKWSQIVDFIENELKPEPFQVIVKPVESAGSDDVMLCTSMDEVKRAFGNIQGKINGLGLENTSTLVQEYLHGTEYVVDTVSRDGVHKVVAVWEYDKRSVNGAPFVYYGVLLRPATGDVLTPIVDYVLKVLDALEIVHGPGHAEVKFVNGEPCLVEIGARCHGGEGTYLPIVNRCIGYNQVECTLDSYFDPEAFAALPDRPLTLKAYGCEAMFVSYENGVLVDYPGLAEIEGMASYVSKMIHVHQNDELSVTIDMFTTPGSVLLVHDDEKQLQQDYERIRELEHEGLYKIQEQVVESVASSKKVVIVVDPFSTGAVVAHSLMERGYECICVYSDKLENIENVASLVPEGLTLTFAATIAFEGKLEKTIAAIKKAASSVAGRSRSSSSEQRDNENLISAVLPGAELGVRLADALADSLGLDANVMEHSSARRDKYLMGETLRQKGVRAVKQVKATTWDEAKAFILDDLKPSPFEVVLKPLESAGTEDVVLCLSMEEAEQTFNSIIGKINGLGIENNAVLLQEYLEGDEYVVDTVSRNGEHKVIAIWKYDKRRVNNAAFVYFGLSIIPADGIVNELIDYQFQVLDALGIRNGPAHGEVKFCRGSPVLIEVGARCHGGEGAWVPIANKCVGYNQVDAAIDSFLNPAAFNSLPKRPTKLLEYGCEAMLVSYKNGVLKALPGLDEIEKMPSFLKKEIFLGPGDMIRRTIDMFTTPGSIMLTHKDKNVLDENLARIRELELDGLYELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDH5</accession>
    <name>A0A8K1FDH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_009925</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDH5"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="14">
        <location>
            <begin position="2"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="11">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="348"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="13">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW58366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="565" mass="63491" checksum="544CCB74D1C953AB" modified="2022-08-03" version="1">MCGIVAIYASMMKESELRQAALEAGKRIQHRGPDWNGIRVFPEKGIAIEHERLAIVDPESGAQPLVSTDADESITLAVNGEIYNHKQLAAELKTPYTFRTKSDCEVIIPLYMEHGVEFLNKLRGMFSFVLYDAKKQVLIAARDHMGITPLYYGYGADGSVWFASELKALEHGCVRFEPFPPGHFFSTESESFTQWYNPSWFDSEHMGETPLDLMTLRTSFESAVKRRMMADVPWGVLLSGGLDSSLVASIAVREKQKLVASGGEWINRIHSFTIGLENSPDLKAAKEVAEFLGTIHHSYTYTIQEGLDAVSEVIKHLETYDVTTVRASTPMFLMSRKIKAMGIKMVLSGEGADEVFGGYLYFHKAPNAKAFHRETVDKLRGLHQYDCLRANKATSAWGLEARVPFLDADFLEVAMNIDTREKMIDAKNGRMEKYIIRKAFDDAENPYLPKNILWRQKEQFSDGVGYGWIDSLKDWAEREVTDRQMKHAARLFPYNTPQTKEAYLYRSIFTKHFEKEVAAETVPGGPSIACSTAAAIEWDAAFKNMADPSGRAVAGVHVEAYDAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEH4</accession>
    <name>A0A8K1FEH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEH4"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="144" mass="16471" checksum="66B0BEE654E1EC2A" modified="2022-08-03" version="1">MLVPKKNRIAVYSYLFKEGVMVAQKDFAKPTHESVDVPNLQVIKLLTSLKSRGYVKETFNWQWYYWYLTNEGIEYLRAYLHLPSEIVPATLKKQAARPTRPQAPAPGGFGRGRFDKDKGVGPSGDFNPEFRRGGQDGYRREASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEI6</accession>
    <name>A0A8K1FEI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_004530</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14891">
        <property type="entry name" value="MYSc_Myo30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF845">
        <property type="entry name" value="MYOSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="10">
        <location>
            <begin position="129"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="9">
        <location>
            <begin position="1290"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="712"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="692"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="223"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW59461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1545" mass="174889" checksum="A70C01655CA202D6" modified="2022-08-03" version="1">MASNRGRVELVSSGALPTHDLFKRKSGAPVDYSQLSINQRLVLENKRRAELENLRRRSTHEVVKALAQTPVEIGAQIWIPDPERVWRIVEIVSYKDDAEKGMVLTVNGKYGREEIDLREIGDLYKVNPRVVDDMTALYYIHEAGILENLHARSRPENLRPYTLMANVLIAVNPLVRTVEPKIQDYIKTQMGDRPPHPYAIAEVAFQQMALRTPAQCQSIVISGESGAGKTETSKIVLRYLTSREHQASLAKNKTKNPTLTKASTTEALAIELDKRLLDTNPILEAFGNAKTLRNHNSSRFGKFMKLQFQPEKNTLCGAFIETYLLEKFRVVAQIPGERNFHIFYFLLSGADDQLRNELQLEAVDKFNYLNQSGCVSDPNVDDELLFDEVLSALDTVGIDSALQKQVWTILSGLLHLGNIQLKDRETAEGDAGEVTPAAQRYLKSCAALLGVDANYLTRVITEREISTRSEKFTIKRTAKEGGYVRDAIAKSIYEHLFKWILFKINHSLGHGASSLPFIGVLDIFGFESFEENDFEQLLINYANEALQATFNQQVFIAEQELFTQEGIDVGKIVWPDNRDCIELISSKPSGILPLLDQEAKLPKPSDEKWNVTLHKTHAGHAHFLAPHEKDKKYVFIIKHFATRVPYTIGNFIDKNNDTIPKDLEDFVMSSSTSLINEIFSTKIENDSMDGPPSSNQSQLRKPSVSSKFTEQMQNLVDTLNATRCNFIRCIKPNPTMTANVFDHGYVVDQLRCSGMLATCELLKVGLPTRVSYEEICRIYKPVLPPSITPLFAPYNDRTFTEAVLWSFRVDPDAYRLGRTKVFFKTGKIALLDALLKVDMKKMGPWIVSRLRKWLARRRWRYATAKIIAQRAFLWLLERIKKRRAAILKLQAVMRMHQARKKFLKYRNAHRNRLRRQALARKRWKTAISATIAGNAFQKLLQQVRARRAADDAKRTSAAITIQSIVRGKLGRKRALKRRQQIEEAKLRQRLQAEAAAQALEKQKTAKRRWRAALQTISAQRHFVQRLHHIRKTRLAVEEARRRADEQQRLLLQQQEEERLRQLAAQREEDERQHQLALKRAAAAIVIQRAFRRSVARDEGRRELALLRARHTSMAAALAAQDAARYAEEASLAHQQEAEALRRLNELEQQQKASMGRLGSVGAAGSLGVAAAANGATLGSAQAISAQPGQAGELGAVGSVGVAGALVGQESLQNSDLSWMAQENIKIEGQAQADAFNQEQLAQAGRDIFGEGADMPQGPMLSAEDDNLVNPVRRIQEFPTGPPIPYKGGIMTCTMLGHRKLQDENWGDEYTEYVLRVTWGRDILEQSKTSWLVGGRYNDFNALHQELKAAASGRRGKRAPWFPRFPKRHPFSSMIGKNQEEKFIIKREKELNRYMTQVLTQMPDALLNVHMDRFLNLTVRTQDISEREAYAEARKRWEEEEREALASAADAEPLNDAELHEVEQLVHQLMQKVIYSSGDIRQDTELQEMIHAVKVLAPRVGASAQIGANVNMELVPLAMQLQDDIQEAFNQYHDTLLAIRLGQDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEL5</accession>
    <name>A0A8K1FEL5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEL5"/>
    <dbReference type="OrthoDB" id="98643at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="224" mass="26219" checksum="C1BE3C39C98825AA" modified="2022-08-03" version="1">MAEGPHLGHRLPWRSLAQVAKRLAMGHFKNFWWPNDHLELYAAKNKLKEEEKAVDHFSQCLADAIKEFAETDPTSYEDKEKYDPSHPDTDWDVEYSYSIGAYVGYYDSLIQGYIELNILLLDPDTWKHVVLRENGKWSRAMQLMCGFTDGRHPKWLADHLRPIFDEHGYLKPVTADVVEIMREHAKLIFRCLYSIGPTNSMLNWKNVKCSHGLEYFAYQTYWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFB2</accession>
    <name>A0A8K1FFB2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFB2"/>
    <dbReference type="OrthoDB" id="68333at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="57100" checksum="2AB5BF4B524ADF84" modified="2022-08-03" version="1">MFHGFDPYTQRTGELPLSRLKLLLKHYDLSVGDVTYRQWEQTLPEGTSAIPLLLFMQACMLWFHEQGLINHYHNWQQSHSIRQSDHQKSRQELGKCHSAPQLLHPFDLLTRRHDTALTFSYDDHVKKPPSPQRTQDEMMASKRNTIIDATQQMRRNTKILSRIESERPLNTKPADTKSIDGASSSSPGKRSTTYDRLHGEKLARHILQRCSTNALAPSTRRRPSVTLIHERERQQQRTLALKRARQQNVETAKAFSASIAMISRHVQNEELRDLRELEMEKQAAIVHERKQLRRLQRAHCLELEREKNIQHQRDVEAMKALAKEEALMLEQFLATRQELVRCGKPTFSLSQSTSTLFAPPPEVLAAKATATTTAQRRRLHTMEKDHLEHMRSIQLLDYVYDKRKAVLDAQRPKADAALVQVDSTPQLPEAQELEILTQDLWQQVLQDCADRADWTPLLPPPNSPPAALRYYGTSRPRILPPFTESTATPSHVSKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFP1</accession>
    <name>A0A8K1FFP1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFP1"/>
    <dbReference type="OrthoDB" id="166853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="33978" checksum="A5E9A1011D76BC99" modified="2022-08-03" version="1">MTEVHDEQRLDHFGSTWCLPIMLLMNCACFQYLLLLFHRRWREPRVMLLLTVSAIGFIVLIPYATRPHLTVDAMNDVSESCLALLLLVQTVLVGSSHSDAPLGPKILKRLADLLILFDVAVVILGFVAIFDPSVVTRFGGADAMNNVSENVTLAFTFLYRFGLLWCKKGWRRLVLVEDNWELFWHAMFMTHEYVFMLLEYKTRYSWERVQGVYMRVTLTPCIWMTVGDHHNFHLVRRGLSEPKSSKATKSVVDPVVAINDKAPTETSKPTKDAAGAPVLDDEQQETKEVVAQEGTDTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG41</accession>
    <name>A0A8K1FG41_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG41"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="17277" checksum="DBA5E436F85D7E05" modified="2022-08-03" version="1">MADVLLNLVEQTPVAGIAVGGALVAAAVGYGAVKAIGGGSSKPEPVEVAKKTKTAKKKTKKAKTAEEPAKENEAEKINLEDFVVDYPDTEEEEAARAEKKKQKRKQKKKNAKEKAKAAASAPTSAVSDSDNAKAKAAAAVAAAKKDAEDGWSTVATKKKTTKVKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGJ4</accession>
    <name>A0A8K1FGJ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGJ4"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="268"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="441" mass="49677" checksum="98A413A5371F62CA" modified="2022-08-03" version="1">MSLMNIAGTQPVDDPEYRYKMPRLQAKIEGRGNGIKTLVVNCADIALALHRSTGEVCKFFGCELGAQSKYDDKNDRAIVNGAFEAGMMQQHLSKFIEGFVLCPSCRLPETKYKFKGQMIYHKCYACGAVEPVDMNHKLTTYILKEHAAAKRADGKDKKKKDKKDKKKGDDEPEKEESAKEKKEKKEKKKDKDGKEKKEKKEKKEKKKKSKDDEDDDDVEWHTDLSPEAVAARAAEAEAIEAAARAAMAADAAAKGSDDEDDEVVATLDNLEVDDENAIESAVANVQRFLSESHSDAEIFEEVCRQQTYAALPIADRLVIFFRAAFTNQILSSNQVAKYTPVLEKIVDGQHAQFQLVALCEHFCAVQHPELITSFPVVLKLLYDEDLVEEELLMSWAKPEVRKLHAHWEVSDEQAAKLATLLKPFIDWLENAEEESDDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGT8</accession>
    <name>A0A8K1FGT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycine-rich cell wall structural protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGT8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455937" description="Glycine-rich cell wall structural protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="36423" checksum="ED63DB84730B957A" modified="2022-08-03" version="1">MKIFVCASLGLLAVLLHATTTDAQPRGMQREQFGGQNGGGGMNGGGFGGNQFGNGGQFGGGNQLGGAGQFGGGNQFGGGFGAGGQFGGAGGRFGGAGGQFGNQFGGAGGQFGAGNQLGGGLNGGQLGGGLNGGQLGGGLTGGQLGGGLNGGQLGGGLTGGQLGVAGGNGGVGVGGAGAGGQLTNGQNGQGGGLPVAPSPSPTPARTVPGQRPRTTQPAANGNNGGTAAATNGANGATSLATGANGGATTGLTNGVGATGVGATGVGATGGLGAGNQLGGLSGGLGGGLGGGLGGGLGGGLGGGLGGGLGGGLGGGFGGQNGGGFGGLGAQGGFGGQGQGGFGGFGGQGQGGFGGQGQRGFGGGFGGMNQFGGGNGQFGGGNGQFGGAGNGQFGNENFGGRVAGLRGRFNDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH71</accession>
    <name>A0A8K1FH71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="581"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1121"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1151"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1194"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1232"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1261"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1371"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="72"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="765"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1398" mass="156186" checksum="7CFA61078B2289DE" modified="2022-08-03" version="1">MASSSQLLHNQDIATKVELALGRAFPQMEVRFKDLSLTVDIITARDRGADSNGSRNADYELPTLPKHVLKTIAKVTTKKTTVQKHVLKNVCGVFKPGTLTLILGQTGSGKSALMKILSGRFPFGKRVTMAGDITYNGLPREQILERIPRYVAYVNQEDEHFPTLTVRETLEFAHECCGAGLSEYTERNLSRATCEENEATIHAAENARCGPDVVMKTLGLTTCEHTQVGNSLLRGISGGERKRLTTGEMSFGIRYATLMDEITTGLDSAAAFDIIDTERRIAKMQHKTVVISLLQPSPKIFALFDNVLLLHDGEMIYHGPRGKVLGYFESLGFCCPPERDVADFLCDLGTPQQFQYEVCRSSSDFDCPPRSSSEFATIFRESAIFQDLMSDLNSPIDSALKVDAEYHMLSAPPFHQSFVAGTWTVTKRQMRILLRNRPFLVGRAVLVTIMGLILSTVFYDLDATNVQIVVGVLFASVLFLGLGQMAMTATFLKARGIFYKQRAASFYRTSSYVLAVSASQLPLALIESAIFGSVVYWTCGFAPEAGAFFVFEIFLMLTILMFLAMFFFISSMSPSLLVAKPLAMVSLLILILFGGFVVTKEQFPDVLQWIYWINPVAWIFRAITVSQYRSSTYDVCEYGGTTYCTPTYQKKTMGEYSLSLFEIPADKSWTFWGIIYLIGTYLVFTFFAWFMLEHRRHERPEIVSLPRGVNTGENSVTVPHEMSYQEMEATEYLKVRSPMNALGRGEIALDIRPTHTSHMLAPVTVAFQDLWYSIPVPDGGKDEYIDLLKGITGYALPGTITALMGSSGAGKTTLMDVIAGRKTGGKIRGKIFLNGYEASDLAIRRCTGYCEQMDIHSEAATFREALTFSAFLRQAATVPDSHKYDTVEECLDLLDMHDIADHIIRGSSMEQHKRLTIGVELAAEPGVLFLDEPTSGLDARSAKVIMDGVRKIADTGRTILCTIHQPSSEVFYLFDRLLLLKRGGETAYFGPLGAQGHAVISYFEALPGVESIQEGYNPSTWMLEVIGAGVAGADLAHSPLKYPSDEEDGRSTVDFVEAYHQSAIKRECLDSKLEAKGIFVPTHAGDQVTYTEKRAATNWVQFKLLFQRFFTIYWRTPSYNITRFAVALFLGLIFALVYHDTEYTSYQGINSGVGMVFMGTTFNGAVGMISMLPFAFAERAAFYQERTAETYNSFWYFVCFTLVEIPYCFASAFLFTAIFYPAVGLSDVSHAVLYWVATALHILFQAYLAQFLIFEFPSIELASVVAVLFNGVWLIFLGFNPPAIDIPHAFKWLYTITPPRYSFAFLVGVVFGECPDEYMDQIRSLRATEDMSSWPIGCQTFTNAPVSLGNMPVKLYLEYVFGVKHAHLTQYFGVFLATIALFRILTAFSMRYINHQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHB7</accession>
    <name>A0A8K1FHB7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHB7"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035461621" description="Phosphoglycerate mutase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32974" checksum="7B2BFD8DEF741F95" modified="2022-08-03" version="1">MLRAVGRYMAAFALSWTLTIAIATAQATDTSVCTMENSAGCAAFTLRLTSGFFVQGDESIDDPAHYPPHLGLEPSKTWGDVDALLKDGSHKLVVFLRHGEALHNADKLRVGEKVWEELQQFLEEYIDAPLTATGIQQAATAGGMLKEEVEQRGLKIDAVIVSPLDRTLDTYAGAFKDVSVKSPVIAMELARETLGVCQCDRRKPIPPKKEAFPSIDFTKSIPTDDDSWWLPDHRETDAEIEERGRQFMNHLFYERSERSFVVVSHSGFTRGCLRALGHRYYRPANGEFIPVLLSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHS2</accession>
    <name>A0A8K1FHS2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_012822</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHS2"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="81"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="196"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="262"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="334"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="399"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="457"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="10">
        <location>
            <begin position="602"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="635"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="731"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="10">
        <location>
            <begin position="732"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="696"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="827"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1085"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1032"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1116"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="827"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="887"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1085"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1239" mass="131977" checksum="4C2E52DF437F2CD3" modified="2022-08-03" version="1">MTDNADACRVCKKDDDEELLVLCDGCDSAFHVYCHVGCVCCSQKPKSSHLRRQATVPDGDWFCKFCADHLPALPEGATPVSSVFAWGDNEDGQLGLGDTTDKVVKSPTRVHQLDGIGVVQLASTETSTILLGNDGNLYSVGTGAAGQLGHSDVVHEKLTKFRLIAAMCADKRSKSEGRFKKIVSGRDFYMALTTGGHAYTWGNGDLGQLGHQENKPKKVPKKISALREMEIPVDQACCGDDFILMTSGETDDSDPFNTHKPGVFMSMGANTQGQLGDGSGRNQWVPQLLNKNAAEYTNSEDAGIEEPAEFLLGRDIRFLAAGKAHCVAVPTRMKGLWSWGFGEFGQLGHPQPPAPSGQSQFFRQQFRVPRPRFVQALANHVVSQVACGGNHTLVLVADGQLFGFGDNQFGQVGVARGEDEESKKIQTPVVISSIAAAGKLRQIVCGEAHSAALTVSGEVYTWGRGQYGQLGHGEKQAETLETPTKVASLPAIKTLYSGPNQLFAVEFTDDTVKEPVVSAARKLFHLGGFRLPEQSDRLRLTMNPQHYATYAQQQQQFQGRTGSAQMGLGGQFATMGRTASSSGAPGMGAVPLHMWTPPSPQEQQYFDLLFSMADEEKRNAIGGRIAVAFFSRSNVDKNILREIWSIADSHQKSELSRNEFHVAMRLISMAQRGEPINVQRFFELAGMPYSLPTLEGVPPPPPAQSPMPQAPPQVHTPSTGGSTGPYAITAEEKTRYDGIFQQYDTDHDGFLLGGEAVGLFGMSGLDRGVLRQVWSLADRGQDSRLDIQEFYIAMHLIVCVSKRNLPLPAEVPSELIEAIYGGRSSFTSTSTAPLATPPASTGSISGMGSRTSSMSVNPPSTTESKGDPMDAFAGLSGLSPPKDASVRSNLGSLSRTNSSSSQAPTPSLSMDAPAAAMSASSGFGAPASMGSFHGAAAISGLPGDQSRDRASSVNSVSSFASVSTEASAVSSVQFKPPMPGPGQQQMGFAGHQTGSFHGASPIPTYQVGGPQHQAQMAPPKPFMSDEEEVNAARQLDQRNEEFVHSLQEVEKKQMAIESLSEKLRELDQLRHDLVTLSMKRDKVRAATTATAASSATPDPSETQARRAVEQSLRELVENERVMIQKLQSDIAGYEKELQEGLLADVESKLTIECPIPSPAATLPSPVGVTMPSPAVSSTPAATGDFGGFGDFKAASPTASASTPSNTGGFEAFGAFSAAPTTSAPATAGGFGAFDDFNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHW8</accession>
    <name>A0A8K1FHW8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHW8"/>
    <dbReference type="OrthoDB" id="163783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37067:SF3">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="905" mass="99766" checksum="926F5545337ED455" modified="2022-08-03" version="1">MDNKEQRKKLHRWEQKNRWMGHYELKYGVQPIEFGPALAAPAGGMTGYADGLPTVLKAKCRFCECFGREALASGMGGLSEDAVMGKSSALEFPGSPMGPSDSSMSMDASGGVGLEPPLKRRKKRQTLKVFGPNFRTDNLESHLTREHPVKWKEYERLRDAEKKGFFPEVPEAKDVFLQAAATAAGSNAISQQRYGNGLGLLNGNGMAGLASGSFVTALMDKGASAGIKYVVPTEIMEMVEQLFTSRAFRAATDATGANSWQGFVREDEKLSEDVVNTDSFLTGDCQSIINEVRSITIKNDSLFQFIVDSFASKLSFESTLAMLHASQRLVPDPTGLLGNATMPDVVNAVHQLVGLNLTSISQWMAYAWGYSLSLRFVTHHSTGFVELRLQLAVHDELQDLHLISLPVEAQRHNVESLGGAIVKALVALDTRAMEKIVGVSVDGDGFHMQQYKGIDVWLKKQAAEVATQSAFYVVHSGAYHVSHIIDELLEQCQADFGFGTTLADLEALCRGHPSLLAAMGPAPSRFAAAQWVSTYNACEWLAIHRETIQKWCTEQQMTSRLPPLRWWIVLFVLRDVLKDVVVAFKKCREQALSFADVQKHLRDLVFQLRLKFNIKPVMPTPGTSGTSASSLSLDPCEFAYQDFVNAIIPLDLFMYEAFQLKSIDGIDDTERGTLYQRFNLQLMLLINKILAVTNVPTDATSGSSGGGATAGGDLVSSAAVTTISGADGVTEATSAQQVDTNTVLPELHQYATEIPASTPYEFITMHNLTFMEMLNEQRTRIRHKWTGKVLSMITDDRNRMVSEFAQRGPLYEAVTLSAKQLQSGAASTFRDAWKAFTVEFSSLHSFAIVFGGVLAVTQTSEEDLQRLEALYRFFRVPTILLEAHFHAAQYNKVTALRRHSDATIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHY0</accession>
    <name>A0A8K1FHY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Urease accessory protein UreF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHY0"/>
    <dbReference type="OrthoDB" id="2550922at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01385">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009467">
        <property type="entry name" value="Ureas_acces_UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="27839" checksum="B71A39276C17B7C1" modified="2022-08-03" version="1">MATTPAVDASPMASGGDWMIWQMVDSLFPTGGFAHSLGLEAAVQENVVKSKDDGVSLRQFLTSTVHQAGNFVLPIVYSSIQATEAAGEDEAALVEQFLDLNARATALYSNHVAKKASLAQGGALLRLAISTYYRTPGDKFQVLVTIRKESKKRKHVGVHHAVVFGVVCGLLGVSASTSQRMYLFFVLRDTLSAATRLNLIGPMEATRIQYEFVPLLEQVMQAKQNRSILDSYSSAPVLDLIQAMHDQLYTRIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI00</accession>
    <name>A0A8K1FI00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI00"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="105"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="374" mass="41681" checksum="C2A0C4597BFE0C0D" modified="2022-08-03" version="1">MWHAGWARSMTATSAATTVVVAALAVLALKALYLPIQRRRQHPQIAAQIPFAAYLSFDLSVRFRRYVLSKGGVSSKLTKIPDVDVLVPGIIRILGKNPSRMTLQGTNTYLLGEGPNRVLIDASDGNLPYIDTLLRVCESHGVTEITDLVITHGHSDHIGGILHLREAFPLIKMWKFMPPHGDDKKLRYKNAECETLLVQPLSEGQTFQIPGTKAVLRTEYMPGHCADHVCFVLDDTKTKQTTLFSGDCILGEGSCVFDSLKDLMASLHRLRAINPRIIYPAHGPVVTDAIGKIEEYITHRQQREDELLRVLTSTEAALSSKELVQKIYEKLPFLLQLAARKSVEKHLDKLLLEKRVVKASSSWLSGTTYRLAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI08</accession>
    <name>A0A8K1FI08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002242</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI08"/>
    <dbReference type="OrthoDB" id="197155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF42">
        <property type="entry name" value="PNPLA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="6"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="411" mass="45614" checksum="610FB5BC9DB920BE" modified="2022-08-03" version="1">MTTESYSFACGGWLKMYLFGVAKALQEHELEKNARVIGCSAGALAATALALGCDFDAIRDFVVDEVVPKAHENLSGPFQVRSYLQATLRSVGHLDRYEELNQDTEKLSVVYSSLSAWASRRVTRFESQEHLEKSLLASCCAVPIAGMPFKLSGEWVMDGGVFDFQPVFDAHTVTVSAFYCTAADIKPSRYVPMWWAFYPPSQRDVEWLFELGYEDGLAWIAKTGKSIKTIEMPTKGASYDGQWTTTVGRVVGYRGVESRILDMLFVGLFVCLWKPLAFVLLYLELYLHAIVSGGKAALFGAAAKLMISSIILVGTILAMATHSFHDMMVFMLCLLGMGIFLGVLVLLSGGIQGAAMVASKDWRKCRACMRNITSLSLFLRTVPVYGSSIVIKRHEYLLEHSMVYRLAMHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI69</accession>
    <name>A0A8K1FI69_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">acetylglutamate kinase</fullName>
            <ecNumber evidence="6">2.7.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_000524</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the NAGSA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the acetylglutamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI69"/>
    <dbReference type="OrthoDB" id="438291at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd23936">
        <property type="entry name" value="AGPR_C_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24149">
        <property type="entry name" value="AGPR_N_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000046">
        <property type="entry name" value="N-acetylglutamate kinase / N-acetylglutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058924">
        <property type="entry name" value="AGPR_dimerisation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22698">
        <property type="entry name" value="Semialdhyde_dhC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="20">
        <location>
            <begin position="327"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW60482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="678" mass="73192" checksum="CF78BC590AD7B312" modified="2022-08-03" version="1">MLPRAVAAHTAIRGHARCFSAKPVVPKDITTSLLQIVSSEKEVHEYLKTYGTPGVTRTTVIKIGGEVIENELDTLVNSLIFLKEAGLFPILVHGAGPQMNAELARAGIEPQYVAGNRVTDKKTLAIAKKIFLNANRKLVDALAAAGAPARPITSGVFEARLKDLDVYGYVGEVSKIYGESVEAAILNGQIPVLSCLGESNDGQALNINADVAARELALNIQPYKTIFINAKGGWIEDDGTKLKEINMAKDYERMASRDYTGRQGTLLKLNEINALLRGLPASSSVALTSAAALSREILSSCSTGTICVRGEVDATPVSATTKKKKYRVGLLGARGYVGREIIRLIGHHPELELVCASSRALVDQNVLEFAQAPPLNPHTNKPAISTGRLTERFDIPDTLQFCDLGLEQIPTSEFADSVDVWILALPNGHCEKYAMVLDNLNRKNKLIIDMSADQRFNDKWTYGLPEAPDSRARLNNATHIANPGCYATGAQVGLMPLLGGKPSVSSSLLDASIPPHVFGVSGYSGAGTGLSNANNLKVLHDNIMAYKSVNHIHEHEVSHQLGTAIRFMPHVAPFFQGIHLTISAQLNDTSLTEKHVQDLYNSFYADESLIQVTPSIPLVKDNSHRHHVTVGGFQIDPKTGRLVTIVTIDNLLKGAATQAIQNINVALGIDEYAGILDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIF8</accession>
    <name>A0A8K1FIF8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIF8"/>
    <dbReference type="OrthoDB" id="94624at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33266:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="34826" checksum="80A90FED766EB217" modified="2022-08-03" version="1">MLLYADPTRDVYVAEYVSEPMLALGAAFAWYQDKFDPLAKCILPHFREMVAHELIRLPSRGVDEIVARIVFLMAMDFAAVNPTERALSSSRRYNGHLTSLRVFLQALSGESFRAIRWTRHGTERDRSSDAEAFVRKWDDWLLGFTQFIQLPRLPTPTVLRVLLERRAAGVFPSSNRSVDWVIPIAKDWPDGEVSMLLVRVEHHLDDDAELNDDEDEMVARHRIQTALRRLRPSSVWAKEPQNGSTRRTFCVSTLTCVTADVGHSRFCTRDVSYTTPSQPKRVSRCVCVVGHGGEAKGCPTMGSCEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIW4</accession>
    <name>A0A8K1FIW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIW4"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF51">
        <property type="entry name" value="LD01482P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="1">
        <location>
            <begin position="140"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="313" mass="35742" checksum="8D676A1B7F843A94" modified="2022-08-03" version="1">MTTASTHVRRQAAANESLLAFIWRWVKNTLWSVLFGQSEWDRICGPVAGPVDEIVRTVKFRTTLALSKALVSTCNVVFDFEGFDVSVVAKDMIQTAQINDNKLTVVENVRSCLHRGSFVNRVYARVLTLKDEAYDSANTRHEAMLEDLWSNLKPDVRRTGGRITKEWGEIGFQGTDPMSDFRSMGVLSLVQLNYFSAKYPVEAQKALVESNHPTRWYPFSVTGINITHFVVELIRERLLDVKIYRFADVRANDREETVVSGVDGIHEIYCDIFVRFNKFWVGSNPRDVMAFPTIFESLKTSIRQELTTSSFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ79</accession>
    <name>A0A8K1FJ79_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ79"/>
    <dbReference type="OrthoDB" id="163959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="18010" checksum="59016F532092A229" modified="2022-08-03" version="1">MVGNPEPLSETPEPASQTPTPQPTTAAPSSIAPAPTTGPSSCDNNWSPMSVQGVAGVFCAPEPVCVADRENGGCPVAQDGLEYGATCGVVRTGVFGCIPNNSSGLPVDIAYPLPTSCAGNEAGDTPVSVEGVGTFCAMYPVCAGEIFGECPGVQEGLDRASVCATVRTGVYGCVLPAISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJF9</accession>
    <name>A0A8K1FJF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Anaphase-promoting complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009043</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJF9"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="372"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="440"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="516"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="568"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="72283" checksum="3F27F55E5537B0D3" modified="2022-08-03" version="1">MRTATYATPTGMWTSSKTASPATTGPELPQTTHDTVTELRRLVRGCIDRHHVASAMFYADKLVTLSPSTPSDVLLFAETCFLHREYHRAIHIVKTAGLLAFETPYTIPPSTLQSYLLVGQSMLAIKHKEECLDLVAKVLPDDEAAIVAFARRSAAQPDETSSINVVSSLALLMGETFEGMGNRDNAMVYYRIALRCDVRCAEAFFHLVEKQMLTTHEQRALLGSLEFSVDETRLLESLYGVHLTKYDAAPSVENRFDVIETKLGLRDNVELSIAKAETYYYYQHDIQKAHEICEWVRESDPFNFKVIPVYVATLVELGKKRELYHYAHQMVDVYPKKAGAWYSVGAYYLLVEKFEAAQRYFHKATTIEPSFAPAWIGFGNAFAAQDESDQAVSSYRTASSLFPGCHLPPLYIGMEHLRTNNLVQAVEFIKQASAICPNDPLIYNELGSVYYKQKNYAMAIDMYMKALELCRHLPERLMEVWEPTLFNLGYAYRKLRRYDDAIRYFRSALRLSPRNASIHAALGFTHHMKGNLEEAIECYHAALAFNPEDSLAGEMITVAFDESLSASRTIQHSLPPPPPPDTAVKRPFSKPGSTSSFGEESVRRNLSLDHSFSSIEHNQQQQSMNCSSLDLSDDSSMNLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJI8</accession>
    <name>A0A8K1FJI8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Golgin subfamily A member 7/ERF4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJI8"/>
    <dbReference type="OrthoDB" id="58259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="3">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="19282" checksum="F548ECA4B9854F3E" modified="2022-08-03" version="1">MAMAARRRLALLEPTGEVFVNGLAFSYEDVFPGDVDMSFAQYMTAEEFQKAITKINDALQDHWPCLPCTSFAYGCCVCTLGLSFYCATAQVHEAETRVNMQIRRINDQANFKSRQIEWQLVRKWYRRASHIEISIANEAPVPKLPPSQAKPAVNLQVLPMPATEVIDGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK93</accession>
    <name>A0A8K1FK93_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK93"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001067">
        <property type="entry name" value="CAMK/CAMKL protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="102"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="410" mass="45590" checksum="5F20B92F2501F8C4" modified="2022-08-03" version="1">MGNQTSAPASPVDASPQSARTDEESAHTPGGGICASSTSAMETLSQWFTPPTSATASASSSPKDRKTPTNSTNTHVRDDGASQDAEIAAAVTVNRRVEHFYDVSTQNLGRGHYAVVCRGKCRRTGQLVAIKKIKRFLTDEKRLRAEIAVLRRVQKHPNIVELIDVFETAREVHLVLELCTGGELFERLADKGPYSEADCVRHIRDMACAVQYLHEQGIVHRDLKPENILLSTPNDDEAVIKVADFGLAKIFTGTNMKTKCGTWGYSAPEMISGSGITFGYDYKVDSWSLGTILYILLCGFHPFDPNGTYSDHEMIACIKNCRYDFKDEVWDTISDGARDLIGHLLVLDPDQRYSMAELLRHPWITGELVAVSALPLSPTIHRDLARYRQQEKQKAFSFEMFDDDDDNQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKX5</accession>
    <name>A0A8K1FKX5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKX5"/>
    <dbReference type="OrthoDB" id="196040at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="971" mass="102356" checksum="1530F9C3CB71BC05" modified="2022-08-03" version="1">MRSVETESMMTTLPSSSTVRGRAPSMPERVIDVESDSPALLMEGSGRDDDQDDDEDSSSGDESESEHQYPRGRLAIPMESPGDDFQSELVLDSTAEDDQRRRAYGRPRRGNFFANEEDERQILQRVTLRRRKEDAKGDGDWFWTAIFVTNILSLAVMVCTMIYLTQTDFFESHQSDLFGTTVDNRFTVVAQENDNAKILLKSGYSNSRYAEAMVSFGSGKLKIGRRPLGGGDTQSFYGMSIFGNGSARFTNRVTAPFVKADYVHAAKAFVFEDGSVMTSAANMSSGGSSSVNEIGDLNLVSQSGSVSMSAGGFPVLQADPDGSVTVLDNEAEYPSAQGIKLDATNHLISIAGDFQIRHGQNSTSLSAREALRLDTTLLLVGKGSATKAVITCPPHKKHSSSDDGRTMELEVLGQSSKDQELGGNVVVRGGDGSIEGGRVRIDGGVAFTAEGEKRGRVMINAQLDPAVESKTEIGSHSVSHEVSLHGAVTINPGIDNKNPTSLTIGGTRVILGAKNITVDNSAVSRSQVQVHSRRVALTASSGPKSFATVELEGNEAVIDARDAVYVGGDARLVQLEGGDNATVALKKAGSIEINATAGITLRSTASQGSTTIIGKVVFREEDDKSFAPDLALSDGKIALDADAVVVGGAGETSSMRVNAKRIKIGALGQNSNIKIAGNTVQVNGATVTVGSQAAGVSMVGKTINIGSINGSLTIDNSGSTASIKAKSVSIDGKTVSLGTGNAESVIVGGADVSESALDAKTVDIGASATSVNVGSKAKSISIGSSRGTIDLKGKVTLNGEELSTRRRLASVDHVYGLAGSDQVQQQFAVGTCELPVHFDERFSSEDGAVQVLEDGLGISPDASATERQHIMLGLSLDNIRAPTTHEDGEKMRLRCRVYRTSQSGNEGVALEVTSNLDPCAGSACDGIFLGASNRRMVAYDSGDRFSVRCITSSTRAVTVFMDRVQLDFSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM69</accession>
    <name>A0A8K1FM69_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM69"/>
    <dbReference type="OrthoDB" id="10617393at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="289" mass="32637" checksum="78A8894724694BFB" modified="2022-08-03" version="1">MATTLAVAPLMPAVDARLCLSLDDLIKERKKENKQKKRESVKQETKPAPQDAKKSKAKAQAEQRKAVMNKNRGLPAPKQTTESSGKQQKKPQQRQKKKKTTKAAAPVQQSAGPSKHQNKKTKNAPHANGSQLSNGQTKKKKTTTTVVEHKKVDNKKMAKPQPTLSPKRQQNKNQRMAPSSPKQNREVTKPRNGVKLTITLKRSRGDVRRMKKQQQQQKKQQRSVVVKPRVMKALLPGKTQPKTKKILAQHIVKKVKTSRKQQAASKSSRQGQFIVRKPVVVRRVKSERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMG1</accession>
    <name>A0A8K1FMG1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMG1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="4">
        <location>
            <begin position="99"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="295" mass="33383" checksum="D1744C8D10C765F8" modified="2022-08-03" version="1">MEAIAGIYDALLLQLPKPMSTDISDGTFGQERLTIKAMKLPQVHRDEYHETAFTLTDGQVSSLCGRGITWRNIGQLKVLYVEDYHDIAQWNDPEAPRKYVPNVVGFFCYNSLTSRFVPIEIQYPGTSIAYTPFGSKNEWTLAKMGLNAASVVYHQWTHFTETHAISSSVRVELFRNMAANHLMRALLEHHAYGDHGMDLIVNVALPSPGTPVDRTFGWGATGSARFAHSYLHNKGSPKNDIPTDLQTRGLNDIPHHKYAQYGSMLYNAINSFVKRYIDVYYKSEFAVKNDFELQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMV4</accession>
    <name>A0A8K1FMV4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMV4"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="156"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="409" mass="45758" checksum="DF63FF6CBDAD5F5E" modified="2022-08-03" version="1">MTSDEVSAVAVDSDDDYEYDEEEAEEEVELGFVSKIEQPLDAKLLHESANWGEWDGGLVGGKPRWLNPATVPSTEALACTECATPLSFLLQIYCPLDDQPDAFHRSLYVFCCRKPGCAKQGSGKAFRSQLPQNNSFYPPTSGIETFETSEPVPSLCALCGQRSVFTCSACHVAKYCCKEHQKDHWSKGHKADCGACQEQNAVVESNESRDTLRTKGSKWLFPQYEVEIEHEPDAGEAVTEHEAKLLADFERNKRMAAAHAKDGDESDPFTDDSEIDVSQKDLNEALGSTAQQDKNYIRFLTRVELAKDQVLRYARWQENSVLWVHEQETLASDAAPPCARCGAARKFEFQVLPQLLFYLQVDQTSSLQQISEKSCEWGTLAVYTCTESCNLNGEYSEEFLHYQTPYAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN26</accession>
    <name>A0A8K1FN26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN26"/>
    <dbReference type="OrthoDB" id="74529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1120" mass="126385" checksum="49C874C49E2BAFEF" modified="2022-08-03" version="1">MRTMRRMSEPSVSPRALKRQRVVREKTDPQVVLPLLALGGNEALNAYWREEIQRNGFENARSVHEALTKLPTWRCDGEMMKEAMTQGDTVFVHWHLTHCAANDPVWLLPLAAACGRVDVLKRVWTSSVDADVAKSVVTTALNEGSMDVAQWLYQTVDDAYRRRMVDEAARYGRLDVLRWLHTTQVDGWLTQTMDLAAEFGHLDIVQWLHVHRSEGCTTRAMDRAAMRGHLDMVEWLHGNREEGCTTYAMDCAAINGDLEMLNWFHVNRSEGCSTFAMDCAARNGRLDVVAWLLSHRNEGCSTRAMDWAAESGHLEVLKRLDKYSSVGCTTDAMDLAAVHGHLHIVKWLHENRSEGCTENAVDHAARHGHREVVEWLMENRLEGCTANSIIWASARGHFAVVRSLYLNGVRTPDAVDEAATHGHWGIVEWLLENQSEWGTIHTLTAAIESREIDITKTLYDRRELHSWPRLAHTNTLVKLSQGSDPRDLAILRHITERRRDRYLPIGANNPVYPAEEEDSGDDSDRTVESTEPFVLTAVSKVATEWNLPEETTAHLSGFIVCDPTTLCRPTIGAQRGWVHWLLRFAHLRPDHMRLVAESGNLHGACQLHDALAKLGGSNCSKRFMYRLMEEGDLDLAKWHIRECNAHLLDEYLYAAVWIGRVDLVEWIHENWSDLSTAYQLETSGQAATTTKTMFNSLMASFSTVQQRFASELMEIETLMSRFKQGNVHPPLLPLSTGDQYFDAADRNRIQTNLLDLAAVKGSLKIVTQLTRFRKGQCTVSGLVGAVIRGHVSVVRQLYASQPELASWPSQDDALVMLRFLLNQGNREMLEFFRRERSMRLEIRDLNQAVALTDEARVQLICELNLVESASEAIEIAAVEGKYDVLKILCESYPATTCSSTAMDGAAEEGHLQIVQYLTERNAPSSRRAMDFAARNGHVDIVRYLGSHRQEGCSPYALLWASACGHTDVVQYLLNSRLVSGGIDTCVAVAEHHGHNGVVAILKAYQATRHLSRSLQCSSRHLVRTHQLDLTQLPTSSSRVIYNELVEKNLVRPQEVYRVLPLDQMGVDGILEQPEQLDSDGIFQWMHEQPVSLGEEQTLQVIDDDVDFDVETILQLLDMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNP6</accession>
    <name>A0A8K1FNP6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">short-chain 2-methylacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="11">1.3.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_003857</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNP6"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000026">
        <property type="entry name" value="Acyl-CoA dehydrogenase medium chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="49"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="164"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="273"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW66092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="427" mass="46803" checksum="8F1912919984F8BD" modified="2022-08-03" version="1">MVMGIGRRMATRAAARALQGSRIEAQRVGTPLVRGARSNYTHAPLTMLTEEEEMFKDSVAKFAADMVYPRVQSMDQAGEMDHEITRGLFENGLMSIEIPAEYGGTEASFMNLAITIEELSKVDPSIGLLVDLQNTVVNNVFVLNGNEEQKQEYLPRLSTDTVGSFCLTEAGSGSDAFALKTRAEVSADGSYYTLNGQKMWISNAEYAGVYIVFANVDPSKGYKGITCFIVDRDSEGLEIGKPEDKLGIRASSTCPVSFNNVKVPKEKIMGEVGKGYKIAISTLNEGRIGIASQMLGLAQGVYDQTIPYLFDRHQFGSPIGDFQAMQHQYAEAALEIESARLLVYNAARLKDAGLPFVKQAAMAKLHASRIAEKTASKCIEMLGGIGFTKYLLAEKFYRDAKIGSIYEGTSNMQLTTIAKIIKQEYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPD1</accession>
    <name>A0A8K1FPD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SMG9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPD1"/>
    <dbReference type="OrthoDB" id="79514at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039177">
        <property type="entry name" value="SMG9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="56942" checksum="7F195106EB5F3414" modified="2022-08-03" version="1">MDREPTPLKQRQKRSGSAGPRRGGAAATNDGPTRAFRSSQPRQRSASAKALAPTGGNVPAPSAILAKPPMMILRAPAGSPPPTPPPAPTMLLHSDAPRAMPMPMHAAPSPLSSPPSSNLYQPRGPPMLRVNTSHAHDGPAHAAPSAPMMQRHPSPHGVPPQPLKRPSHPGHPTPSPVLLRAPAGLPPVVTRPASSVRVIHPNGQFAGDLLSRLGSCLDLTNFTVVGALGFQGTGKSTLLSVLATKGDPKPLASIQDLHTLRDRTKHPFFPTQPLEALLNARTETQGVDVFVACAPKQRANRGGLVLVDTPSLLGSSLCVDQVAKSEGSTGSRYGALTPEQHVELWSVQLAVLLFSVCHYVIVPQSAVVDVEMIAFLRKVYDKMQQMRLPNVSGAVKDRHTAKLLIVVNGAEIPIETDDEQLNVLEHVLPPEWLYRERRLPTAGSTTPSPLWAFPWVDKSDEPSKEARAWRVTALNWSRYMSTLPNSPSFSSGGVHTLTLKEWLSNTARVWDSVKKSGVLTAEYSTRDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS91</accession>
    <name>A0A8K1FS91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS91"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55036" checksum="DCC95551DD885F15" modified="2022-08-03" version="1">MKFPLQHNPFPPLKLSQDYIDSLLRLEQSIVDQTVAEFEQFAYVQNRVVDKTKWKHVKTRENMHVYRAIGDHSDDPHLIMQEMLLDASASSNMATSRMNVKGGARLIAVGSVVGRVNDALFIDGSHTEEEMQIRSSYVPDECVDWRVLYNLCEPTHDNPLHTSMIKYHVMATTGAAGLAVRPRDLVMLNCTGETILSNGERVGYGICHSLDVPGCGTVEGIVRAQASCSYIFRAQGRNSAEVYMRMVSEMGGNVNDSIAALSFASSMIAIWKMPWGGQNVKLAWMLKQQRRNRSRKESSHASDCCQVCQRSFSLMRTDMKCGLCRELVCSSCLVVRKISYVRPGRHLLQVPTGFCKHCILQASLLDAADIARKEYVPKQASTRSGGFSSVSSTTPTTHMHDSVVSDGSSASPSSGVDLRDAHVETVEDWEKAQYDPQGTVYSPLQQEATNTQQLSAGVGVDQHQMNLLLQMEQLRLAAEQTYQLTMENERAMNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSB9</accession>
    <name>A0A8K1FSB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="1">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSB9"/>
    <dbReference type="OrthoDB" id="337745at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="2">
        <location>
            <begin position="80"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="227" mass="24937" checksum="024A6690C64AC9B0" modified="2022-08-03" version="1">MVAFKPQTIVDYTTVASPSATQKTLLAAFESNAAYDQSVVQTLEQYVDEQIQTATVDVDANLALLKLYLVYPEAANVDKIQKVLLKAITALPSSFFLGAAAIVPESFREDATVKQILDAGFLLHACRFEEFWQLDLAFAGAVADFADAVRAYVLTVVEKTHSSISSAVLQAKLNVSDVKDIVAAKKWTLEGDVVQVPANDDNQMRPKKIRENIEFDDVLKAIHTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C219</accession>
    <name>A0A8K1C219_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000169">
        <property type="protein sequence ID" value="TMW54923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C219"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29242" checksum="3EFD773411B197DD" modified="2022-08-03" version="1">MESPLPKGDYDYADLETKKASAPEPSAPPATELEAFVFPTESVESSHHEAHNPAVLTPTISSASEKWLFASKLALFQILNTILASAALITVATIVFLSIALLPLCGLGVFVYRGALPLVCGLAILDTKLANLITPVNDRVCFMNGRPGAKSILCVAPNLHEVSRESIQVVVYFLTLKALIGFASFVMFALVVLPFLPIMREINGYNSNESQWAAGFNVGNLNFFADPVWYMLGCIGIMNFTNLLGCYSRDLTRSVCCRTVSPMAVPVAMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C274</accession>
    <name>A0A8K1C274_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C274"/>
    <dbReference type="OrthoDB" id="78487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="128"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="294"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="675" mass="75893" checksum="1F66A9F93D1E70ED" modified="2022-08-03" version="1">MEVIGEETTETTALEDGVRASKAKARWKKLRAATCVFILFRRRTTHGVRQQKLSRKAVPVFLGERNGRGASVFASTLFSPRGTGSSPHVAKLYAMKLERFECLLQKPIQNRSDIDIKLLAEFIRNTRFFTDLSSASIDALARHIRFCEYHEGEVLYRQGDTIHEVCGRCMVIRGSVFVYKNSDYVQSAREGEDYTGWYLNAVPGSTREAIKYGDCIDTCNIGDIFGDDAVYANLFRERTVIAQENTVIACIIRTDYQQTVRFNIPNDNQLIDHSNRTSFSALSSSFAILDTMNLAHRLTTNQRVQAAMSLRYRCLTPGDIVFKEGHEGQAIYIILFGKIRLCTMRASEAKTSGGSNDLHGELVIELGEGDVFGEEAFWDMYGSTRSSTAIAGLDEVETEILYLTRADYDTILGCGLRSNQRTNNTVVPMKFFGLQQQHMTAADRWRMAIYQVIHCRTSRSQWLSVISMAHERRIDLLFDIVKPLFTDTPRHQIKQLCRSAVLRTFGADSIVYSRGDTMVDECFLVVSGSVALQQTFFGAGNNNAALANANNPPSTDTTSVKVTIHVVESGGIFGEFETLGNCSKRHISAVVLQPDTKLLLLPAEDFVSFWPEKSRLDAKLALLKSQIRSVCRLDLDQTCSLYYAAHHQSYRRNDVISGKQEQEGSQRYIDLEITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2A0</accession>
    <name>A0A8K1C2A0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2A0"/>
    <dbReference type="OrthoDB" id="167389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="26811" checksum="AFF7A7FB5F53FCCB" modified="2022-08-03" version="1">MGSESESARFMASRAARASAQRELRPAEAGSDTDGESVERGHVTMAPETEWDGYMARKHVGVIRNDRTPLNTPYTPHLVKFQLTRLEEDDDGDRTSQQPFELGATLQATLSRLLQPFGYLRSGIDRIMWALLPAFITQSVVFEKHRHWVVWYLTTILSIPFVMLLSPMVIALCICTSPIWLAGMLVLFIRAFVSLNKPQHLDEDSFTHNGNGHILNGTTHHDAVYRRPGMPRNGMNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C324</accession>
    <name>A0A8K1C324_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">MtN3-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013133</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C324"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000007">
        <property type="entry name" value="Bidirectional sugar transporter SWEET7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF30">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30428" checksum="B5F1ED0DA5F7A50D" modified="2022-08-03" version="1">MTSTFVTVLKVLASLTALYMVFSPSTSMYRIHKNRSTGVMSVIPLIGLFVGCHTWVVYGYVTDGYFPMVTTYAIGDLAAIGFIAIYYRWTEKRRYVAKVSAIVLVANVLLTAYAILGKEGVLSQPYSQVKLIVGYIGVAAAVSMYASPLATIALVIKTKSAESVPVAMVLVGFVNNFLWTLYGLLIDDMFIFGCCLASEIVCILQIGVYIVYNPKKRAGLSQELPDVEHELSTVPHHGQRKASLSSSVAIPSQEIDLTSIQIENGGGFVALQSPSRSNAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3F1</accession>
    <name>A0A8K1C3F1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sporangia induced parkin coregulated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3F1"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207:SF2">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34071" checksum="AF8B72B66F550291" modified="2022-08-03" version="1">MSSRIPNVSTRIVPKAIALPETGSCFDTTIVAPKRRTSSEKHDDSQHIGAFSVSKPTKPHTTDNFLRKGVGLGGTGDIERGKQEKLDNLSPRSKTQRLAFKERPNPPDTSFRRFYERGDLPIQIDHGGVRNMVAWKVDITKLDFHHYLPIFFDGLREVEEPYAFLSEQGIKDMLINASTKVLPVIPQLIIPIKNALNTRSATIIVKTLHILQLMVTCESAAQPGNGPGLIGQALVPYYRQILPVLNIFIRRNDNLGDAIDYGQRKQLNMGDLIQQTLEIMETHGGDDAFINIKYLIPTYQSVCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3G0</accession>
    <name>A0A8K1C3G0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010319</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3G0"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="31"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="167"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43412" checksum="292FBCCBDAF43D53" modified="2022-08-03" version="1">MARFRLSALPWLRKSPVITQSRCFSTPSECLRVAIVGVGRMGQIRLRGLQQHPRIQIASIIDASLTGANAARYEAQYNAPCFLSLADAAALKDVHGVWIATPTPTHLPVIQDALTNSKTLKAIGIEKPVAGTLEEIDQAYNHCFQQNVHLVCSFQRRFDPSYEALRRQCVDEGRLGRLQSIHTVFRDHPCPSVEYLKTGGDPFHDLAVHDIDYVCTVVGEYPTRVYAYGTSLSDELKAVNVMDKASVWLEFPRTGVICTMDMSRRADYGYDQRVEVSGELGMLQVLNPPRTQIVHSGGHGVQGDTLVHSFPERFQDAYERELDHFVDVLDGKTMPRVHWNAARMATIIAEAARVAATQRKVITIKYVETCQDQPRQDPYLHVEYEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C416</accession>
    <name>A0A8K1C416_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008725</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C416"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046354">
        <property type="term" value="P:mannan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="585" mass="67324" checksum="6F40C72C6C897E49" modified="2022-08-03" version="1">MFVQRIIVLIYSLFLFVRNRVPHKKWIALVLASLYIALRTTGQAPVVGQPAPQIRINVMNTATKYEGLHGLPSTVTTLWTDETFECIGWKRTHTCRKEEENQDPDDTPEPEKDFFNCSDPIRPEMAGYCIVRNRTSGDLFKLMSSSCDSLATGEYTCDMARNFSDYAVHSLNYEHKPLAPSLALPSFTSSKRKLTNGILMIVYDKVLPSAFATIRMLRLHGCELPVELWYRPDEMSIDNPIIHRLLSDFNVRIRPIFDNRAKGFHVKPYAVYYSNFDNILLLDADNIPTKDPTYLFEEPEFLKTGAIFWPDYWQPSNSLFQLTNTSLLWELTGVDYVDQFEQESGQVLINRLKSKKALDKLMFYSTHQPRLLEELHLIWGDKDLFRLAWLNTTQPFHYIQFPPAVGGLELQDKGIFCGLAMVQHDVQGNLIFFHRNSIKLDGTLDQPRIMTHIQEYSLEGDPKEYRIFQAVHAHKECCYYIGTQTLPDGQPATQITAVDSTIYASLEELAIQFSIEGRTLLLAEEAKKQRMLVGDISPSNLRIQEIVALFLLAYVLFIIAYVWCKARPARERLPSRWKPLESKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C478</accession>
    <name>A0A8K1C478_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008753</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C478"/>
    <dbReference type="OrthoDB" id="114727at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="387" mass="43419" checksum="787DE072BC81F1F7" modified="2022-08-03" version="1">MAVEEPSGIKTDERPTEEPKPVKKKKKNKPQDSTEATQPKKTKKKKAPSVQIAVEPPSPIVSLPKEAQDQSSAWSTNLGGYSTGYYRVLLETQRVEALCRSLTLRYRDIAALRSAFDNEDWDRTGYLTVDEFIHLLKEEKRPLTTGVFEHCGLGKRAKRLNFDEFVLCIVTIASLSRRELIHYAFTLFDKDESGIMDAKELAEFCGNLKNKGFFFQGNVDIAQKKLTELAPTNQAKRTNGMGNASAGDGLVDFEDLAEGSTHFHAAFYPILQFQRKFQTVALGEAFWDQIIFRKAQVERIVHYMRLHDGHLPPLTIRERARALGASALFVITGGMISPSDVYTLRKAAVAKYAEEVHQVKQQVAARELAEAEAEAAEESKNEQAQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C490</accession>
    <name>A0A8K1C490_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C490"/>
    <dbReference type="OrthoDB" id="2379186at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="214"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="473" mass="53664" checksum="1C810A93EC875D0B" modified="2022-08-03" version="1">MEAPSFQPKPVKRQIVEEAPDIWMEALKDGRVEVRPRDTKSLRDYLKRELRVKIPITERLAQKVSAQDTEDTCTSVFTKLFQSHQAISAHTAMVLHSAIHPTTCGFDFAPKATYHHFWDSLIGVVLRLVSNGFYRRHRDVPGLFCPDFVFYYAGKRVCVFRGQEEGSGEMDVPIRKMSENMVWRHDDAPYLFGYIAVRYQVCLVVIRKGEDACRPTVEVLEQYDLGKVCGRLSFLLALLNMSTLFRSVDEQIRYANIREHDVTVQPNGVTIRCGKDSVLQEYPPDLPSESIIKNLKKLHTLMAKQSVPNVVCLAKANTKERHVVLRPLGLSLHPSDLKQLLMALRDVLNALVTLHSIGIMHRNLRWENVLKHPDDCDKWFLTNFDDAVLVPAAQGVQHLSDDSHAPEVDSEHAVEVDIWGVGHLLRTTNVTNIPSELVVMQAECLSEKPRSRPTATLLLKQVEAMLTPGLHET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4I8</accession>
    <name>A0A8K1C4I8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein ENHANCED DISEASE RESISTANCE 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4I8"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045096">
        <property type="entry name" value="EDR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136:SF41">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY (PH) AND LIPID-BINDING START DOMAINS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein ENHANCED DISEASE RESISTANCE 2 C-terminal" evidence="2">
        <location>
            <begin position="74"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="304" mass="34154" checksum="7B7E97A954434DC4" modified="2022-08-03" version="1">MAMTEHEPSIESTDATSTTTSATVVDEATAALAQLQCVEASEDVARKTTTPAAAHQLTEDLPFSVYSPSIRTMWSEPDADQVLVRGSTYLDDQVKVAAGPSLGKLLHVDVWSAETPEARHHIARFDHKRDQSVLRYCEEKHPESLVFILNIELPDADNVSLVSYWLLPNFFSAANTSDSNFSRLLRTFYEADNSWCDNRFKLIPSFVNAPWLLSQLVPSRPALTGLRLTQHYHRADNYFELDLDVSSSTTARYIGSLCQSWSMYVEMDVFLTVQGETEDELPEQVFAGLRFSYLDLSLATTIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4L6</accession>
    <name>A0A8K1C4L6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-adaptin appendage C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006434</name>
        <name evidence="4" type="ORF">Poli38472_006438</name>
        <name evidence="5" type="ORF">Poli38472_006440</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4L6"/>
    <dbReference type="OrthoDB" id="69705at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="2">
        <location>
            <begin position="506"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="623" mass="69981" checksum="64C9B3111B619E7E" modified="2022-08-03" version="1">MLSDLLLVRLTNKKWQRKPRRPSNDKILSGSVDEVAKSWDVTKDSVGVSHQYPGHVLGTISIVGNKAGTHAVTSSLDCQIRVLNLTDGSVEKTIDAGAGERECRQFPRQEAMPLEELSELTTGKNCGKSAVLAQILREIEKTVSVRGTFAAVDCVGTRMDEEMIGLFTVLQFCSPEANKDKGEMHVKEELEQLFEGPDRQKLYTSLIYRDVMANVDNVMISKSYELIKPEEDTPVFKFRAAQMWTEADQINVKLKVRNDGSSPLHVFAVTVKAFEDSSSLGVMLLPSESVAVLEPSQERTVAFQLKLAHAVDLPKDRHYGLYFAHSALRAHLLEGKLDGTKLKLVDKKKTQLKTVSDSISFKVDESASLEGSYSAFPFSMWRVMSIGVVLCVGLFATMFIRRKRIRFEWIRSMDCLKTRPLKYKTSNAKMTEMTVKKPSYDPVEDALDLADLETLESDGLLSDDMDDEPIVKPPTAKREKMPAITMQWRKPALPRDRPTIRRVLALDNTQRLNPKRFENMWEEYVQRHNASFRAAHRPASSAFLASMEAVGIVCMASGTVNGVEKYVLYAKQKDTTDYFFVSIDILVATNETNLSIRTGTDTNESLIQQFVALVDAQLDKLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Q5</accession>
    <name>A0A8K1C4Q5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_006477</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Q5"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010556">
        <property type="term" value="P:regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000172">
        <property type="entry name" value="cyclin-dependent kinase G-2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="72"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW56467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="44367" checksum="57136A29493A6747" modified="2022-08-03" version="1">MGGYKRNRWDSDSDSEEERRRERRRRQRDRQDESRGDSREEAPPAETQEATYQARQLVHNFYLHGCRSVDNYARIGKIDEGTYGVVSKARDKDTGDIVALKQVKMSQEMCHEGFPVTALREANVLLALDHPNIVKVREMVVGSTPDKIFMVMDYAENDLKSVMETKMKHPFLQSEVKCLMKSLLSAIAYMHERWYIHRDLKTSNLLYDSKGVLKVCDFGLARKYGSPIRSYTQLVVTLWYRSPELLLGATEYSTAVDMWSVGCIFAEILLMKPLFPGRGEIDQMDQIFKVLGSPSDESWPGFLELPNAQNMKWKWPKTNKLREKFPLAASFSGGGSSLSNAGFDLLNQLLAFDPKKRISAKDALKHEYFRESPPPKAQELMPTFPSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X7</accession>
    <name>A0A8K1C4X7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X7"/>
    <dbReference type="OrthoDB" id="6222486at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09271">
        <property type="entry name" value="RNase_H2-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="16561" checksum="D0B9ACF0D433491C" modified="2022-08-03" version="1">MATHDERGAVRVCLTRCPLPPAESGVHSLPCHIHHDGPAGIKSYFRPEKEEEDSSAMDEKKKNSAAWRAEFRGIALRGKTVALNELGMKGLLLEDAGMRHPDDEGRIWEVESHFDELTSWEVPGSGADELDLHATLQQWTAVANALHGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Y1</accession>
    <name>A0A8K1C4Y1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Y1"/>
    <dbReference type="OrthoDB" id="298589at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="983" mass="108258" checksum="9BCD2ABE0B0F4DA5" modified="2022-08-03" version="1">MATPLALEGDGLIENLFHFLWSKDDFGDGPRIFVPHTVVYHFTQPSAWYFTSLKSGKLKKKNKVNLTNFQIEHAFTKHLRKGTGVATDIVAYYLYQLPGTTTVSTNSSASLGNDEETQAPPTVIEYFDAAALHDFLFTREKTNNGILQRFVLPKGTHNATIRAIWSPKICLLERRVNSKSLFDKHYSVYERAVTFDGGGAGELFSRPEPVRGAMLPGEVQLLCEQIVDHVTQVSYHKFRISRMVLHLKSDADDRLWLLWCSSLRLLRVHASEASSMRPLDIVSDAQVPAHVSLGHVSHYSLSPTSIKKSKSLKTLSSYHRHLSAHEIDAPLPEGFQRCTSCASVGDQPRMLLTNYRAVLEHFQRFLAFLRERINEKEQAAIEWPPDERLIKAAGGVGFGILPFCERMPSAGLSATSLQARNLVIPPVIQYLHPTLTVEDFERHRLDPIFLHRPVAVCERCCLVYADYMTLALEANTLRSTAPAILRPQREVSDLKRRLDPLDPVSMATSTLRKPVSPHAKSASKPPPSAWKPIPAGSGTEKASKAVSMLTKSTLHALPPAPKMPDRIESLAEFTGCSSEEVLMKTASWSSGCGSGTTTSPGMASQDAQREETFFRELYHQRGQVSEGHPLQHMLDSASLLSQDAKQRKNHLKTVRASGTSLGKSASMGYLDSLLAARQSKQSANPYKQVQKLRVVGNKRTKQKTKGIARSPASKTKSNLSIVVDDRDEDDLGSDVDELQNGSKSRHTNQGGTSSSPASSPKQRFISEREARASEAHQEFLFAALYEAEQQLEHMESLASIVLPGSAVDVEDEAFDDGTFPAPTSTTVAELQALLSENATLQYPPDFDTTTELDVDTSLATQHEYDEVPSSDDADMDANAYVNVNDVEASTNAEYDEMLASQYADMDQIVDGSTGEAEPTADEEHDEGPAFHYADMDTNAGVDENEVEATTNDEFPGGPTSEYADMDINAADEDPITDQDNAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Y5</accession>
    <name>A0A8K1C6Y5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014829</name>
        <name evidence="4" type="ORF">Poli38472_014837</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000121">
        <property type="protein sequence ID" value="TMW57682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000100">
        <property type="protein sequence ID" value="TMW60972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Y5"/>
    <dbReference type="OrthoDB" id="164026at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="965" mass="108140" checksum="752F7A3BD4591EDC" modified="2022-08-03" version="1">MAPDRAPGPDGLPLAYYKTDIHLWSQVLECVYAAQFALGRMTKFQRRGQIILLYKKGDKRDPLNHRPITLLNMDAKIPPKVLARRMGPALQTILGEDQYGFVPSRDIRNAHLRFQALQQLYKKKNTTAGAVLLDFAKAFDSVVWDALDLTLTHFGFGENFCEWVKTFFKDSLVSILFNGDPLPSFQIGAGVRQGDPLSPALFVIYIEPLLNLLRATMKDKGLRSAPQDPSHTVISFADDVTGLLHDLKDAPAFLEVVNEFCEASGMKLNTDKTSAFSKPVLVGFSSPIIRLDTMVKPVTPDAEWRQTWLQSAPSLDNVRPSDQIFASAEEIFIDPNATPEMRREAALRGVPTPVADDLRYNMWIPASVLTATFKDTEILTSLGQSSQPSVWMDNCVNGNIRDFKCIKNAGISFVCTDRFICQKLGGTELSICGKKFKVQTYSRYTHWYYVDLTRLPDETSDGEIYDWFAEQGAPPVYITPTNSIRGLHSRSRRVYFPTKTTPACFILPGEKPLRQIGFRAGFCVVNHRIRAYNQSKPPFLAALQTQRQELKKQEKNEKNEKNQSKSKPAFSSSLQADIAKSSTEKKVKDGDDDSMEGDSEYNPDDDEGGDGGDFPMSSSSEKSKSRGSSFDSDSDPHSDDEKDDGKVVVNPATIWRDVSKPPPNFPSPPDQRSEITFFQVLGQRHTLFPDAEIFSAKDNFKVKVLPVSQNSYPVFATVNPFEWIASGETDDLPPDVDILLTDDNKKLIASTVKMQKRAKELLDGARTAFDVNEMSLEALSNFLEKILSELDNTESADDTIAKIQAQPCFLRPILSKTVPANYKVLESKIVDHAYYRVVSERTKSKTNARSTFAEKLKILFADQVPSDAITALQKLVEDPDEFKQQLRLAEIDLCLQVLAPGIYFDPYKISAIVQQEVTRLSNSRWLLWDDATLELLLHSDFGTNLLKTKIPTQLAKAVTEARARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7W8</accession>
    <name>A0A8K1C7W8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7W8"/>
    <dbReference type="OrthoDB" id="163979at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="284" mass="32745" checksum="8F0C045B591328C8" modified="2022-08-03" version="1">MVLSDARMHYYGVLYLGPVTMIINFALFQYLCGMYYQRRRERRVKLLLFFGLIGFVSLIPFSNPDPLVFDHLNDISETCTTMTFLVQITIIGRDINRKVRIRSLVWLTYISEMFTLIGVVLATKSFVEVIAPDTGLEQFDFIDDIFEDVSLWFIFVFRFYYMALSKGVRWLLQNKRLELFLYALLMTHEYPFLALNQTTGVSWESLQAIWHRLLVTMCLLQTIRDKIRGRSTPGGNSLRSQARDTNGTMSKGPQAEDLALCKGATTLSARNTLKQGSITPIMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C905</accession>
    <name>A0A8K1C905_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C905"/>
    <dbReference type="OrthoDB" id="78284at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="484" mass="55859" checksum="63FBA75E59F95840" modified="2022-08-03" version="1">MELSANARKLQEEEVERLVKCRLRSEIEARKAVEATMKRAVQEARELKKELMVLREEKEELRTAARKATLTAATTPSTGTSGASTSNTSTVKDNMQKKLAHEKAKRQEAVQQLEQLQTQYRALQTQDEERATHVAELEKQHEKALKQTKDELHRRQRELQTLEDDVKRLRSAADDAKRKQQRALKDKGVEIQQLMDENDQLRKKSETFERQADETQKLRRQLEKAKEKQNGATDEWQRRLDQREQAFLRQEESNRQQIQEKQEELNALQTQLENALSRIEGGERERQDQEKRFEATLRAERTKFEELVRSTKQLQEKVLQARESAQAAERDRDEAEKRLQQQVEFRETAERAADAVEARAEKAEQHVEKLKQQLAKLESALLKKGITLEYLLKQPQTVTTAAKTTGTAPVNPRKEAPREPEDDSEPHQATRKTSKPPTMTTTRVVSKTKTMTGGPFATPLLTKKSPASNNNHAEREATPERSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9J8</accession>
    <name>A0A8K1C9J8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M16C associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9J8"/>
    <dbReference type="OrthoDB" id="10250783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000013">
        <property type="entry name" value="Mitochondrial presequence protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000057">
        <property type="entry name" value="Pitrilysin-like metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="10">
        <location>
            <begin position="523"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1047" mass="117179" checksum="341B095EC72EFBFA" modified="2022-08-03" version="1">MVAMMLRASRAFARASQTSTRLASRSLSSAVPLLKRGDGCEALQVGEIYHNFTLKRKTSVPEYNIDALELEHVRTKANYLHIDAKDTNNVFSVMFRTPPYSSNGIAHILEHTVLCGSHQFPVRDPFFNMIKRSLNTYMNALTAYDHTMYPFSTVNEKDWDNLRAVYLDAVFFPNLHRLDFLQEGHRLEIVEDKGGELELQYKGVVYNEMKGVLSDANNLFATKVQQALMDGTIYGHISGGDPAAIPDLTYKELKDFHAKHYHPSNACFYSYGDLPLTEHLQYLDENIMSRFEYRADSAAVRVDNAVPSVDIIKKTGSESLIIVDGPTSNMAGAEASERDPNTKFCMTKYLPLASTDPFETFVMRIVGYLLTNGPSSELYKALIESGLAQDFSVGTGFDTSTYYPTFGVGVEGIEGEHAVPEIQDAVKRAYESVVKNGFDKQRVDAMLHQMELSLKHVVGNFGMNLMHGVSSVWTHRGDLMENLQLNPLLERLEREMQANPKFLEHYVRDFLLRDDTKQVQVLMRPKESYVSDQEVKEAQRLADLLMEQSNNDLDRIGKTAKELEKYQKKPQPVECLPTLTLADIPVTAEDNFDFVDTERISTSEVPTQFVKVPTTNEISYVRVLFDTTQRLPLEYQLFVPLFTSVFGSLGTSRLRYDALPTVIQNCSGGISCSGLTHPSLSDAATTSHQSILLGTLSLPHKLDETLQIMHELLTDTQFLDPENLKQLRILLQMGAANASNSISSSGASLAGKRSRVGLTDAAFYEELYSGLTQIEQLQKWAQASDEELVEIAKVLQTIARTVFTPDNMRLSVVTEDKLRGQASTALEQHLLNPLQRSVSTTNDVLPSADVATMPSLTPAQRTFFGFPLSVNFVVETLPSVPFAHPDHVPLTVLAQMMSSCFLHQQVREQGGAYGSGVSQGEGTFSLSSHYDPNTLKTLEVYEKALQWAADGKFTDRDIQEALLSIFASIDAPKTPSMKGKMSFLRGITNEMRQERREQYLALSKTQLVDVATHYFAVKPPSHVVIVGKESETKELQREYFEIKQFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9V8</accession>
    <name>A0A8K1C9V8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007279</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9V8"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF2">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="540" mass="58697" checksum="A1C2AE469C9E9143" modified="2022-08-03" version="1">MAALKDEHGRESPRVRPDHQIPRGDAAAGHNVDGSVDTKVTVDEDIAMMETPFYVDTTPGQNPKKLDRDVEAKRQYPFAQRPQAPAHSRTLTTVALFCLYYFTVCGGPVGTELSVSTGGPLLGLVGYIAFPILFNIPIAYAIAELCSSCPEDGGFAIWILNTFGPFWGFLEGYWAWIGSVLDRILYVNILYGYLNELLDFSSLSSVAAYMIKAGMALGLTIPSLFGSRTFSLVLTALLVLVIIPVLVFMVDGFVETHSLDQLGDVRVAGITVFDDGEGSTDVEFEGPMTVDWTVWINTLFWNLDGFYYVSVFGGQVANAAQAYPKAILWSGAVMWLSYVLPMLAAVGANTPHWSTWDEDAYPSIAQAIGGDSLYGIVLIGAIAGAVGMFLAEVYCEALQIWGMASCGLLPKIFQQREARFETPLVAIFFSFVIVLLGLTFDLNAVMGVKNALAGAVELLILAAAVKMRQELPDIPRPTKIPGPWIAMCVILAPSAFLLVFLVVNVMVEPTSAIAFLVITAVGGILAAIQHWNFRRYRVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA23</accession>
    <name>A0A8K1CA23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peroxisome membrane anchor protein Pex14p N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA23"/>
    <dbReference type="OrthoDB" id="441517at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="3">
        <location>
            <begin position="8"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="287" mass="31537" checksum="C5F94CFB58ADA5D4" modified="2022-08-03" version="1">MASDAAFLAKCEQFLLHPTVRALSLAQRVDFLEKKGLSPAEITSVLKNVERQNGLSPLLRTPLPSAATASTAAGAIVQKKPLPWWALVVRYGSAAAATLVLAYAYVRFREHMMSKMLQAQRDEQARRRQKRNATVVDLLAVISQQRKQYDEVVKRVQSRVSRLQTLKATALNEEKQKTSVVTDARQLELQALQTQVLELKSAVTTTFSSPPESPPHSLSSATSTQSIEKSNDLSTANSARNSQPSRPAYSLPVVPSSFTATRSPLESTDEETIQERVSGRSHLALTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC03</accession>
    <name>A0A8K1CC03_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000286</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC03"/>
    <dbReference type="OrthoDB" id="79068at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="56066" checksum="E12E91E4AFF570F0" modified="2022-08-03" version="1">MHKLKKRTNTTVAVEHKVATYRNAYGSHFECSSTCYFIMLAYSIGIAFLLVLLAVIPVRSPMSAEEAPFLIYKDNQGNAVAQRGMFGRFVLWLAGSAVIVEARGDAAAKIENQDDLKERFHEDVEAIADKFQEVSPSKTFESVAVATDDLVFSPPPPRQPPRITTDDCVLIDDVDRLFDFPGKSPQGSKKPGIFSPVTPKATFPDKTGGDSVFTFEQTSPSSSRCGSLLPDQIKRKSIGAGSAVSEPENVIAAVERRNSMLKRVEKRKEQAKSDIKHDQLDDRELEMYEYLEFVRELLEGITIKKICQKSSRVVKRFFFINPTLSVVYWNKVGNKNWISKKSSVECAAIDKVVKGINASPNLEHKGKAAKQALYLSLLTNKGRRLDLEAKDEALRQRLYRGFTRLAKEKREEKARREAEGDSAGTPSALSPSESRHGSVGATEARTGGDPSSRREPSVIRRVSAEAERMAKAEEDDPKHWREEAEESDEEGDEDETNQGDNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC54</accession>
    <name>A0A8K1CC54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-soluble NSF attachment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000559</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC54"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000049">
        <property type="entry name" value="Alpha-soluble NSF attachment protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32841" checksum="C74970E74E3567BE" modified="2022-08-03" version="1">MSADAKAADYYSQAQKALKKSTFFSFSGGTQKYEDASDLFEKAGNQYKIGRKWQEAADAYVKCAECQMKLKESSRAAQFYQNAADALSKVNPTDAVEYFKTAIAMLCDAGRFSNAAKLQKQIAEIYEGQDNKEEALENYRQAADYFSGENQQSSANNMLLKVAQFSAQLERFDAAMEIYESIAKSSMESNLLKFNAKNHLLNAGICALATKDLVLVQMKWQEYQEIDYTFADSREGKFLQAMVQAFEGFSSDAFADAVYQFDTISKIEPWKITILLHVKESILGEVDAAQDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDK1</accession>
    <name>A0A8K1CDK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Chromodomain-helicase-DNA-binding protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_000680</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17995">
        <property type="entry name" value="DEXHc_CHD6_7_8_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15565">
        <property type="entry name" value="PHD2_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15566">
        <property type="entry name" value="PHD3_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055198">
        <property type="entry name" value="NSD_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059153">
        <property type="entry name" value="NSD_PHD-1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF11">
        <property type="entry name" value="KISMET, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23011">
        <property type="entry name" value="PHD-1st_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22908">
        <property type="entry name" value="PHD_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Bromo" evidence="15">
        <location>
            <begin position="248"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="380"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="501"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="17">
        <location>
            <begin position="788"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="1010"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="1327"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="1791"/>
            <end position="1838"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="20">
        <location>
            <begin position="2045"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="2160"/>
            <end position="2215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="445"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="675"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1530"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1686"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1959"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2022"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2222"/>
            <end position="2307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="676"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="720"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1696"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1722"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1743"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1965"/>
            <end position="1979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
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    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
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    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW60638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2307" mass="259888" checksum="9BCE6649EC6F7AA1" modified="2022-08-03" version="1">MATRAGEMRPPKDATVSKEHVTNERIVRAAVDGADQTAMADTVIVAVVAVNSTDVNGDAGDGRRRRRASTKSVKYADDDGSDEEQAIVVEKKRRARQLDSELRVDVGYPLLEQIVGRRINKRSGATEYLCKFLGRSYLHLWWLTFDELDLFIPEGYQKHHRVQIYERKLRREGYQDLDDVDDVEANKVTIEKILNHKIDPREHLDEQIEKRRRQLTMPMEFPRVTDYFLLDNADSLPERMIGIIKKLMNENGGEIFSQPVDTEEITDYLNIISNPMDLGSIATRLGRESYYVGPSAASLFAADVRLVFDNCKTFNAEGSDIWLLADELLKTFEKWYYDWILCPTAWLKLQPSGNQEVDRKLGKDFREEGEDSYDLWLPWQTGCSICRSNTDSEQLLLCDRCDGEIHMYCSTPELTELPEDEWFCSYCQVRNQFENEAKIKWRETLQGSAESEGESAGVKSETKTDPVSPKLGDKNSPVPNILNTAIDGAKKFNRNTDGKQPTLDRKKDSKPSSVKDRATFFLVKWVGLSIRYSTWERAEDIGDDEQIQRYFKFSRVPTVKEVRETTCQLPCCARRNQLLLNTVAQRCCDKDKFCTRGFQHEGECSREIKTVDKEYGTYPYRHLRMVEQVKAQLYAFHCLLNNHNPDKDVLKQCGVYTNAFVCKKQYLHASLRVQQEDGDEDYSEDENASESSDDDYEDEVDEDDMPFRFRRPVSLLPGVADDDSVEGDDDQLSKKKAEDEVSEVLGALVEHVALGYPTNVEKVVQRVSYNSTYPVSSFQGSPSFTEYCVALRKSSLGLGMRLGVGDDGVASVLGFQRLANGMVGPAEASQVITPGDVLVAVNNVSVGKMVFQDIIGLISRSPDFIIFHLHSRRPAHTYPPFCQPKHVFLQREGVHEDAVAESEYIPFSFNNCKPMLKVGLPSTANSESVQVTTFITPTGPMQHLYAGIVDNSIDPHEHFGSFLPAKKTNVATTTKVKAEKSEFIPYEHSPTFKGGRTLRPYQVEGLNWMITSWKAQRSCILADEMGLGKTVQVVSFIEHLRSEESIRGPYLIVVPLSTIQHWRREIESWTDLNVCVYHDIGDHRAGKFTAKDMRAVIRNQEWYYPGLFGSIFKFHVLLTTFETILADFEEFEHIHWRLVVVDEAHRLKSAGSRVLKQMRSLNTDRKLLLTGTPLQNNTQELWVLLNYLEPVKFDSMDDFNEKFGTLQSQEQVLQLQKLLGPYILRRVKEDVEKSIPPKEETIISVELTTLQKQYYRAIYDKNKSFLYRGTKNSMPTLNNIQLQLRKCCNHPFLIKGVEERELEELGDRPDAAVIMEKTVQCSGKMVLVSKLLPKLKQEGHKVLIFSQFLKQLDLLERYCEANGFGFERLDGTTSGSVRQNAIDRFSRPNSKTFVFLLSTKAGGVGINLIAADTVIIYDSDWNPQNDLQAQARCHRIGQKKSVQIYRLVTRNTYESEMFNRASRKLGLEHAVLGTASFSETSQPDKPTAEQLVELLKRGAYALMEEDDTASKQFAERDIETILKENAHVRVMNQGGDKVEEDESGETKSPKKSRKRKSLAGIAFDRSSFVAEGASNDLSVDDPNFWEKVLPGAMSVEMLSVKLEDGSALASRQSKIKFMSNLDISLNELVEELRNGNEDDSRSGLNLQHEYDIAIQVLHQITTKHKKDFSNDQLDLVKGYLNKLEKSRVRSCRTAPSKKETSQVDDFKKRRKSKSSANGRDASDDEILSSDDDDEDEDEEGTKKAKRSRKKKVVSTRNDASPARSRPSKKRKTPTGFEAPSSMFSGVINDSDDLCTLCGDGGLILLCDGPCHRSFHLECVGMNEEPDDERWLCPDCAAGRHMCLICKQVGEMGVEFGVIQCSVAKCGRFYHKGCLAKHPRVDWVGKKRFRCPSHFCHGCSQEQQLVVASSKKKSSKREPVVGCIHCAQSFHPGCIKSSEQFIRLSTNLMICANHLRPKKPIKAENGKSSIKQESAQTSRNGHTKESVEEIPELEPLDEDVSPAELKKIAEVPALKVCGLCRQGDTTDPEAESSSKRGKRSTKADAGVTSVEGPFIEAPVRLQLADKSTQLVYLHMNCALHSPEVYVKPDGTFCNLQRAIKRGRQLKCTSCKEVGATVGCVVEKCRCNYHLRCAVESGGEFIGSPYTLYCKSHAEENHKEPKVFCTCATEDAEDRGLSLACGSCQMKFHPKCVNMSERQAVRKTKEKTWVCAACTGVATSVTTNATKTNGTTKPKKAKSKQVDEPTEPALEPATSEDNSGRRSSRSRKRGAAQPSPPASKRSRTTKRSTTIHAISPHLDGSDCSISDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDP7</accession>
    <name>A0A8K1CDP7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDP7"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30046" checksum="78DB4633A0A7D195" modified="2022-08-03" version="1">MSAQCTLIADQTDDAVQLALGFVALSSLYCKWHFETPRRPAKIWFMDAMKQGTSALMIHVLNIFSAIATANFSAQPSDADECAFYFMNVVIDTTLGVYIAYLLLNVVTAFAMRRNWPSLKHPGRYGDPPSLRVWTIQLLSWMGVLVVMKAIVAIAIYIFRTPLGFMGSLLFYPVHNHPKVELLIVMIGCPLVMNMVQFWIQDSFLKDHGDREALPLLNKPVSNLQVHAGPTPANKKKVGNLSGLVGDKTQNVAPKQEKTASNAEDMYNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE94</accession>
    <name>A0A8K1CE94_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE94"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="28080" checksum="33FEE1F071FCC3A1" modified="2022-08-03" version="1">MPGRGRKPEPWVTWLYKETLDEFRRLQAKGAKVCYGMLRDIARYILRKSKGEFTATSVCGEKNTKTLEERITNTWIRKFCEHHNIVGPASTRRKGGNGINVWLEEAGRDSTPPRRNRPETRSQRKKPPTKPSSPVVIDTTRSQRTEDQGTTEAADQDNRHSYLISWLRDAFEACQRAICEEEDASSVGAASERTALRKIRIKNAIDEAKDAIEAVKQSKDTAVVHWLRRFQRAVDAIDKQVRPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEF3</accession>
    <name>A0A8K1CEF3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glutathione reductase</fullName>
            <ecNumber evidence="12">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010992</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEF3"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000235">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="7"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="357"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="186"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="50"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW61929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="488" mass="52718" checksum="0691BD10C8B4A289" modified="2022-08-03" version="1">MSSSTVYDYVVIGGGSGGMASARRAATYGAKVLLIERGRAHDGMGLGGTCVNFGCVPKKVMFNAAAHVEHLGRNADYSIRTATKDFEFGDFDWTNMKNKRDAYIARLNGIYERNVGNAGIDLVSGIATVVGKDQIKVGDQVFTGKNILVAVGGVPAMPAIPGIEYAIDSDDFFKLETQPRKVAVVGAGYIAVEIAGVFNTFKTETSLFCRYDQVLRAFDPIVRDLVNEEMERAGVHFVRRSRMERIEKQDNGKLTIVATVDGKEGQTFADYDQVLIAIGREPRTKGLGLEEVGVKLSQGGFIEVDKQENTSVPGIYAIGDATTTGWELTPVAIAAGRRLADRLFGGEPDACLHYHQIPTVVFSHPPIGTIGYTEPEAVEKYGADKVKVYTSKFVNLLYAMADPENKAKTAMKLVCVGDEEVVVGLHVAGEGADEMVQGFGVAMKMNATKADFDNIVAIHPTAAEEFVTMAPWGMIKDKVVLPPTPKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CES0</accession>
    <name>A0A8K1CES0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotinamidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CES0"/>
    <dbReference type="OrthoDB" id="1739143at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457037" description="Nicotinamidase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32553" checksum="C0C9CB1F4F184DBE" modified="2022-08-03" version="1">MIKWTSLALAFSLVVGLVAPQATSEAGPMHASRVLEGGLALVVIDQQADFHPGGSLAIPTANEDAERIAKFIDTHADDISQLVFTLDSHQRYHIAHGIFWTNATGSSPDPFTEITHQDIVNGVWSPRDETLKDYVLAYTSALESSKKFVLNIWPEHCIIGTPGHNIVSNVHAAALEWAKKKKMGIQYVLKGTNSFTEHYSALRAEYELSYDPATKLNQELIDNLAKASKVAIVGEALSHCVNYSVRDLVADWPASRRKDLYVFTDCSSAVTGFESVGEEFVADMKTAGLNVIKSTEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CET0</accession>
    <name>A0A8K1CET0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CET0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="17220" checksum="B0D0AB8FF69B37F1" modified="2022-08-03" version="1">MRLPVVNHYVLALGYPYEGPFYGVYTREGVTENGFLVFDYVSTDDDKVLSRRVLTATRTGFYLKSEKTQANIKNVHRKPFDDPLLGISMWQWAGSSVIVNPWGWVRFVYFVFAVDVILKLFVLMLVVFRNFPAWETMGRRYLRVHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFI3</accession>
    <name>A0A8K1CFI3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycoside hydrolase family 5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009582</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFI3"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923:SF2">
        <property type="entry name" value="ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923">
        <property type="entry name" value="MAJOR EXTRACELLULAR ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="176"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="565" mass="62878" checksum="310CA6D34CF2D4E5" modified="2022-08-03" version="1">MATTYQGEVESPGVTPSYRYSNLAAENIQRQSQSNDVPVDVFVRGSLMDRGIRAVEMADSGKVERSKHFKGRLRRWPGLLLLVLLAGAAVFLVVRYGIMTHESSQDRAAEYEARKFNATKIADGKKDTQKDLTDDGVVGNPAHYPKRACEMPNYLSKNGQIVAVSTNGTEVPLKIKGINWFGMETGQAIPFGLWGNADNGTTAYQIASFLARNKFNAVRLPLMAAWILENKEPNTALLNKGENQAINGTNYMSLLQSIVKALQYRDIGILLSMHTLTYNDNGMLWYNDAVSEENFLEAIDILTKNLCNNDYWNIMGIDLKNEPYKGTWGDGGPTDFHAGAQRIANRMLKGCPKWMGFVEGVNAQHTIVIDGEEFGYYDWYGGGLHGAKKLGMEFDIPNKVVWAPHYYTPAVYPQYYLYGGGKVAEDKSIQDYVELDDDTLRHRIKVTMDDMFGFLASETGPALLLGEFGGLYSHDKHPKKTTQRCTDFTIEIITKPGWAGGFAWSLNPESGYLYNPGDTYGGNNEFTEGLLTTDWLGVEKPFLDGMAAMDSMENLQPFPCFAPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG06</accession>
    <name>A0A8K1CG06_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG06"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="370"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="510"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="545"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="578"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="611"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="644"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="677"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="745" mass="82783" checksum="BFD1DBED611BEFA5" modified="2022-08-03" version="1">MKRTLEHVNNPASDLDTDDEFSFPRTSTRRLSSGLLKRERRALRSGSNVSQGALSPSSFARIRRRTCDLEFHLREEGLIRWIFSFMDVREHQLLKSCCRSWMKIIQAMSVDNLDLSIRSPITSVTVDRAFLSVIHSYGSVRRIDFTGQRSLSDRDLLVLTSCYWPNLEHIIVDDCLEISDFGLLSILNAQSQLLHTISMRHCKHITGSFGPDKINGRHPSLQVLDFSDTRISHTIVHGLENKFPSLQQIHAMHTPAHFDFFHHMHWDDLLEELDFLVSNELSDLPHLTALQEEFVSRAARWLQSQVSNKKSISVFYGTLLSYGKAALVNAPLHRGDYMSALLMACENGLTNIVPSLVVEGNAWVELTDKDNASALGIAATNGLTDVVRLLLEAGADINKRTHCLATPLYIATEMNWDDVIDVLLTSNAQTTCSVVGGATALCVAAKNGNHKTVLRLLGAERSTRRSNTASARQLLQHTQALFLACERGYEDIVRDILNLTDAHANVLMDNSVTPLYLACQMGHERVVALLLECGANPNFRRPNAGGVSCLYIAAQEGKVSIVDLLVRHKVNVHARMEDLSTALHIAARMGHTAVAHLLLREGACINDQTRSGLTPLYIACEEGHLPMVEFFVANGANLNLQTRNGTTSLFVASQKGHTQVVRVLLLAGANAHLPKNNGTYPMDAASLLGNYEVTKLLLQFGARVGGLSLHFAERRRDLQLQTLLMDRYYEQHSQRASDRPTGVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGA4</accession>
    <name>A0A8K1CGA4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGA4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="17576" checksum="48F223B867DE9E25" modified="2022-08-03" version="1">MASAVCLTHSSYPDFDFFVLALEEALQVLAAREPVYFDPVALQLICGIPPKSTIRTRFGTVTCLLMRSTDGVLICAHSCGGGVTAYLASGNVVQDNEGAFVDSSVLPPVQRNPEYEDDEDLEIERTPRTTKGQPTRIDLRGCFINHGDMMRLSHGLASNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGX2</accession>
    <name>A0A8K1CGX2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGX2"/>
    <dbReference type="OrthoDB" id="127396at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16134:SF119">
        <property type="entry name" value="AT02038P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16134">
        <property type="entry name" value="F-BOX/TPR REPEAT PROTEIN POF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="70222" checksum="8117C69002331F08" modified="2022-08-03" version="1">MPRFHALPIAVAQHVLTFVDGNYVVDVMPRTPQLPIQLFQSLATVSKAWRSMLGELKRLHDVSMLSVHLETAGEDEVQDMMERLQTRGARLKALTVAMGVSRRYIPAFDIRCARRSDEALDNTEIDWKGVFRLVPKLQRLDLSGVPMHSMHLRKILLAASAHCPEMKALALPQKEWHRGLVTSQWQPTMDTLYTALERWHHSTPAHGLIQLTLPQRVVKTDDNQTDFHALTDTYLRVIARFCPNIEYFDGWKTSYAEDAGRIHCQELLYCSRPAWEAFCASCTQLREVNWFVLPFINDFFDAFASTTKSKLEKLTLAGGDHGNYPDVAVFGRYYYDGTWSCSSESLSRVFQACPSLRELRVVFQYSFYDDRDLLKAVNDAALVAAAKHCPRLERLEIEELEHPSFMDIMRGITDAGVIAVAKLPDLRSIRLKSTACEAPGIISLLRHAPRDGAPRTVEMVIGNTCDGTRTRSRKRNFTPMHEILIEVLLYLLECPEDIEGRRFHMMLNGHANPSNPETMMRGKMVRVIINELQHTCPWLSLSVQERGTRLTVVLSSIQSSPPEVPQPFVLSRKKDLYNEVREAYWLPSDGSKTSWGTLGEIIVTAMRWPWQSLLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHE8</accession>
    <name>A0A8K1CHE8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHE8"/>
    <dbReference type="OrthoDB" id="93559at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443431" evidence="2">
        <location>
            <begin position="18"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="36987" checksum="3D1B4B64CAF73713" modified="2022-08-03" version="1">MFRSFIVALLFTSCARAYAPCEDGQFEMSVEGIEGIFCVADTPICIAQESNGSCPDVQEGLPYGSYCGRVRAGVYGCKVLDAESIKTLTPAPAQETPAPETQAPQTQAPQTPAPETQAPETQAPQTPVPETQAPVTQAPQTPAPETQAPETQAPQTPAPETQAPVTQAPQTPAPETQAPVTQAPQTPAPATPAPQTPAPVTQAPQTPAPVVSIVPPRGPYCGGLEGWSPMSIEGVEPVLCVQEPACVADRSSGNCPGPQEGLQWGSYCDVVRTGVYGCRPYNGTDIPTDAVYPLVRSCADNTAGDTSVSVAGADTFCAFEPVCSGNRKGNCPGKQDGLDQDSICVGIATGVFGCVLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHJ1</accession>
    <name>A0A8K1CHJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHJ1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="61625" checksum="AA3020D2FC6A6B0B" modified="2022-08-03" version="1">MEIPRLVHDELLQKLEEPREAHLLQAVHDLEHGARIVEDDVVDKSLVAPKHTEKTPLLMAGSHVVTVDSDLDLKELAMKLNEEEQAAVRADAALPAMEIIKSEFKQLLLMFLPLIFSFLMEQLPFTFQAMMVGRTDESRSAEILAAFSLAGLFQVITVVPLLNGIGTALDTKCAQAVGGKRFREMWMFVQASIVMMLVCAPFIIVIFANGATILKALGQDPVIADVTTTFLWTSLLSTPFLVLYSMQRSILQAQNHVNPVAAASLLAYVVSVPAAYALGFWTPLGYVGIALLNTINYIIKSLSLGIVLARHKTSRETWPGIQLREASRFIPKLLHLAGSGVLLVMFQLVGTTVIAFLVGLLPNAAVMMSANSIFSSALALAILPTLGISTAGSIRIGNALGAGQSRRASLVGQVTTWSCVTMGFLVMITAFAIKDPFVRSFTPDADTIHEALKVFQHLLFVFFLLGFVHGQQAVFLACGEQWLCAQLNFMFLFVLAVPLGMYFAFSLDMGVTGLWSGYVLGTFGLILGGGLWYYRLSWSEMTHKARLGTQLHVEERDTPTAAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHW8</accession>
    <name>A0A8K1CHW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rab3-GAP regulatory subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rab3-GAP regulatory subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38572at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026059">
        <property type="entry name" value="Rab3GAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029257">
        <property type="entry name" value="RAB3GAP2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032839">
        <property type="entry name" value="RAB3GAP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472:SF0">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472">
        <property type="entry name" value="RAB3-GAP REGULATORY DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14656">
        <property type="entry name" value="RAB3GAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14655">
        <property type="entry name" value="RAB3GAP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab3-GAP regulatory subunit N-terminal" evidence="6">
        <location>
            <begin position="123"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Rab3GAP regulatory subunit C-terminal" evidence="7">
        <location>
            <begin position="1273"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="957"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1125"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1437" mass="161075" checksum="2CEACA14647EF5E3" modified="2022-08-03" version="1">MASTTQHTTLEDDPLRAEEQVTSPNADTGVVSTESEAVDALSVLFRVDCGAIRDENDAPVAIFQQQSVKMDVAIDRSLVIGYETSLYLAQPPKEASNAEDKASTALVLLEDEAKTTLEDDELIADVKWIGGDHFGVGYTSGIFRVFTREGKLLLEQKFHHAAILKVDVSASVSTKPSGNILGRTDPSASVSASDSDGPTPDGEIWILHDDSTVAIVQVQELLQRIRALSYGPTQVGKFRKYALRDQADITTALSCGPARPTIFQSHSRLGVHTVVSVGADPFISFYHAGNDQNSIIHLAHIATAIASRAAGAVWSFAKSWGWSGSVAADGTEGAAEVRSIDEAAEHVAAPLSSVRSFPEDQRRRSRMLVLCPTGRLAAVSDTLGRIMLIDTYRMTIIRMWKGYRYAQVGWMHGVEGKRRSRGLYLVIYSAQRGIVEVWRARYGPRVYSFAIGDSARLFTRYDMQQQRIRCMVLTGGADGLTDMIEVHADAPSASILMKYFTQNKLQEENFLLHQIIGGIQAFVKKKRVDASHTLEQDSVNPLLDDIGQLSSPTSIQSLVDVLLAQDMAFLSASFVLRALEQLQSVLRNGLASHSPSGTELSLLWQLQWRQRVLSAFIGLHTEYHRSKHIIAHAMKDSSTMLAKHVTNDVEIDSARSRLVPWLELYRRAGYNWNDESHESIRQASVRAGQLTWWDFMECFSMPFSDPELPRRRDILALYERTDKSEDFIREAFRALGVPILRTSVRGAPFFALLTFLYTPVLSNVFAVQELQSLHESLFLSPGDFTSMFLEWYFSLPVGAILAIPPPSLSSSFQRWLQPSISTWDFEQDLDQDGHDDLVHSNKRRLSSCPESLGQIYRACIRSQRLVHVFVLSEHCRWGEQQKSKSFEETTLGKFSSIDGGLRWSILQDCLAQAVHLSLRLGRLGRIAVETVENVDDIMRSIALMQLNEGQDLDDLDLGAKPTIEGSTSQDQESNKQDAWVASLEDSRNATQMKSWAAVLKWYPQFADADSLYCFRASLLCAAWNAERSDMHQLEDAVVELQAISSTRLKLAMGVHVWEKYIRVHVVTLITFWEESAAGRKPPRGLQPQIARRFFGIIKNLLTTLHTAVDGSVFIQDEANHNSLDPDAEEDDEEDDEEDEQEDDDDEASNENTHAAFTMSSLTQRRRWNCRVRHLREAFRMKWPPSHEHASLIQSLRSFSVDQVSRHQISDHLSLILLLDSFAATSVTPVSIVRLFANKGRHLCRPETFTSTHQETTSAEKKMIHKERTHFLRQLLRYDETLGFALAEAFELPTEQIREEYVLFLYQCGSDEVADFSLDKMKRPERIVSQLGSIARARLALILSRMKTDPEFAMVMSVLPADLFAWIVAEKSPPLVADAQVAKLDEAPSLTATSMLLLKCLGLMQPTGPEFEKISAMSVLVKDVIARVKHQQQFTRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI83</accession>
    <name>A0A8K1CI83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI83"/>
    <dbReference type="OrthoDB" id="91652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="382" mass="42505" checksum="C204E7201D541BA4" modified="2022-08-03" version="1">MTMTNKHGSKAPSSTRACVACAVERPSADFSRNQLAKDQPKCRECVAKALAQAEEEQELAAKIKRCMQCFQDLPKEQFSKRQYHQLDGKCISCVTQLERDAATQSSQLIGKWSYDRYYRCCHRGKSGGVGVRSRCNIASPLVGHIPLGSVFRATDVIHNEQGDAMVKVDLLNGPVVFSGSESEHDSPKRKARDGWVPCRSIRNEVMIERHAGPWQQSSRYYRCVIEGCKVRCLPDLALSEIGYVLYGDVVEVLECVVSSEGIVFLRLHERYFDGPAWVVERTLDNESVLNLVEGPSTQSEQYRCVQETGAPTRLEPSLTAPPVGRIPCGALINVIERVVTPERQIFLRLPSQEDATTLWVIETSTVCASVMIKVSKDALAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIN1</accession>
    <name>A0A8K1CIN1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIN1"/>
    <dbReference type="OrthoDB" id="90120at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="2">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="2">
        <location>
            <begin position="449"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="867" mass="98905" checksum="D412281DA12595C1" modified="2022-08-03" version="1">MRYATPIPEGITVGAVIGKGGFNTEMLKRDYDVNLCVNNTTVSLKGTQECVEKAKPWLEELFKQLQVNRPAAHAIRVALKDGDKHCWRFERFQEEGTRIPLGSSKRAQYQYRLVRSAEAAEVEKGDDNAWIQCFDQSFLTRMALDMKTLPKQSDAQIKAALGFTHFRVSPDQANQTYTWAKLQGLPGNMSSWKNQCDPSSTKTNALFTTLMKASSENLKPWKYRLTMYLKNTERQNHEVTLKFRFRNGEWEQRRAPLDRQVHHRYNIELDNSISLTDHTAFRVRVFSRSSVPDSNVCLHSHVAFDHVYAHDPFTTTVALAPEAPPGLTIYKCVVKKKKHVEYEGLRFTLEEQVEKPTSTNEAFIATDDKINCVECRLARSYDDLPLAERVATLVTKLAALLGHQLNGEKNGTCWVGPLMRKDRILFPSVPLPSFCFLRHWTMSYVPPRQRVTQRVPIPEDVAIGAIIGRGGSYQKSLSATHGIKSYVDPAKREVVLSGGGSSVDDALEELLGKFETLKVAPNSSKTQLRTSTRSSQEPRLGGAVYQNALKDADKHFWRFEEVDYDDPDAEISPYKLVRVFTNVLDEDDDDDEDDVVDAWIQHFNQAFVLHMVGEMQTLPAVVGNEEVKIKAALGRTQFGVRLHPVGRIMTWQELQRLQLFRQINPRWQNMCDPLSMSTNALITKLQGMTSEYTSPPQAVLTVFLKRGESRRDEVTLKFHYSDGQWVPNREPRGRSIHHLYNITLDDETAFRVRVFSRSPVTKTEYEDLHSKILIDTDDEEDLFSTIVMLSSDAPRELEICEYNVKMKTHIDYDGLRFTLAHQNADRTDMRLECRLLPSVDPAKPTLSKTIETLVTKLTTLLGHEWMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIU7</accession>
    <name>A0A8K1CIU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_012859</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIU7"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="21"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="193"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW64237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="38030" checksum="2D311B5279B500BE" modified="2022-08-03" version="1">MVATRSGSRPSPTAEKKRSADAEASPAPAAKKPAAAKPKALEVGQTVDKDVTLENQDGVAVAFADLYKEQGVVIFMYPKANTPGCTKQACGFRDHIQEIKDAGFAVYGMSADSPKSLLNWKTKQSLSYDLLSDPKHELIKYFGSSIGGTKVQRSHVIILKGGVVGDVQPKVSPAESVDRAVEFVTSHKQNGSAVPPTPVPAASVASSTFAVGQKTTFDTELETDDGAKVHFQELVHDKGAVFFMFPKADTPGCTTQACGFNSHIEEIKHAGFQVFGLSGDSPAELAAWKTKESYQYGFLSDPKHALIGHFGSSIDGNKVQRSHVIVLPGAVVGDIQPKTSPVDSFTKALEFVKAHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIV3</accession>
    <name>A0A8K1CIV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acyl-aliphatic-L-amino acid amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acyl-L-amino-acid amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002694</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.14" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIV3"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.900:FF:000001">
        <property type="entry name" value="Aminoacylase-1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052083">
        <property type="entry name" value="Aminoacylase-1_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010159">
        <property type="entry name" value="N-acyl_aa_amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01880">
        <property type="entry name" value="Ac-peptdase-euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892:SF1">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036696">
        <property type="entry name" value="ACY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="11">
        <location>
            <begin position="187"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036696-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036696-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47968" checksum="BDF05216EF0ED45C" modified="2022-08-03" version="1">MAQRMDPVTRLLELLSFPTVSADGPKGVYEECAEWLRAYLVEIGLAVQVFEPEPHKPIVLATWKGEDETLPSIILNSHYDVVPPLREYWTSDPFQAKVLEDGNIYGRGTQDMKSVCIQYVEAVARLKSKGFVPKRNIYLLFVPDEELGGFGGMRNFLQTPEFKSIQPVAFAFDEGLANTTDAYTVFYGERMAWWFYVKAEGPTGHASRFIPGTAVSKIINISNKALAFRDEQEKLLNADAGCKHGDMAKKKLGDVTTINLTMLKSGVTADGGQTYALNVIPTEATAGFDVRISPEMDVELFKAMLDKWCEEEGVTWEFPMKVTGPLPKHAVTKIDDTNVWWELFKGACDKLGMQVETEIFPAATDSRYFRQLGIPALGFSPMNNTEILLHEHNERLHKDTFLRGIDVYEAIFSDMFAYAGRDGESSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ55</accession>
    <name>A0A8K1CJ55_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ55"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="19284" checksum="8B64DBB0DA5CAA97" modified="2022-08-03" version="1">MIDSLAFLASIDRIAIAKTRYRLVDMTFELEVTFAEDDEPASSRDSVLSDASPSSYQVERSYSDLLELHQAILNTARHSHTHDAEECTYCSAFVNHCVMLEENLPTRIGRLFVPTEMMHMMVEGMLAQILSLIRSKLKWESNTELCYGQRLLPVIFGRFLDQELFIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJU8</accession>
    <name>A0A8K1CJU8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJU8"/>
    <dbReference type="OrthoDB" id="79367at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="375" mass="40442" checksum="0E8C9135EC3F319C" modified="2022-08-03" version="1">MGGRSASNAAWEGHAELQRALEGLATAKGVSANRVKAVATAACQYTKDYKRVVHDVEVFLWKAEPEHRLAGLYAMDAIMRQSQGKLRAKDPFVKRFLLHMNHTISAVKKLPADQQINISHVFEEWQTRGYYTSEEIEEAGGYMYSMNNPERLKDTQQSASALKASPTHSDAASKEKLASLLSIIKKQKELHETGQQDSTNFPAGNCRFGDRCSFAHGEEDLDKLAVGKRRPSPHGSYDSRWQADDSGASAPASGYNYLASAYGGNYQGYSGPNGGQGGSNYNTSYAMPSQDSHVGNVQYTSYASSTSQPSTSGGSVTTESRPATSANGPGIPSPATIQPPRATPAAPVAPSTRVKDDDDVEASGPEFTLQYDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKV5</accession>
    <name>A0A8K1CKV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKV5"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="522"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="621"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="881"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="932"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="988"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1058"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="526"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="627"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="933"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="998"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1135" mass="125537" checksum="6A3D3FAE897BAFA0" modified="2022-08-03" version="1">MVQSAVIHQDFEYTGHNAVLHTVCFNPQDASFVSGDDTSLRLWRPVRNGDVRQINLPPRTSQYIQALTFIESRQMYVASALDGTLRLYDVELNELTSIFTGRAVIVSLVFDSKHQRLFTGGIDGCAVWQLRGKASLNPENVLNPSYEIAALPNFFHYAEKILGKPTEEVGESEKAEKSTGKAPKKRFVRPNDIAWVQSVQLNSEQTRLYAQGKYQIDVFSTVDGHHVDTYAQLYPREYGAITAFVVHEKTQYIVCGSVSGALFVLSVCPISLIHIFKDHTTAVTGLAVHGSSGLILSSSMDGTVRLWDLDARRQTHRLDVRQPVHAMGILVPSANPYEFYCRVRSSVQIFSIRSAAKEHLASLTPTSILQRVVTPTAATIYAPEVLLGEREDTKDNSLFKLAALRSKDERAHDAELEHQLQQMQTPTQWIVAAGMDRTIRVFSGRAAHEAPSFTWIPEETTLNVIGFSLHPKGTRLFLLLESQKLVLVEVVKLEDDDQNEERPRAPVTQIIDLDPCNGPFKLSGKSCETGNKSPSIRSQKKERDTSTSSSTPASASTTTIMRGAIRSLCCCHYPPIFRASMASSSVVSTPSAYAPALTSDAAHARWFSRTFVHRRQQTKRELKRLDSSLSTNSSSSPEKPQETASPSSPSSQRPPLVQSEREWVVCGSEYGHLVFWHAGLGPSFADAISLDAHDAAIVAIQAGASSALLVSLDAAKRVHLWQLQPVFNLRQMLELHESPTCWVLSPTSELLVSGYEDGTVVLMNVSDALSASHQVETFTGDEHHFAMISAADFLDEKQLVLTASVDAVIKVWDHQKNLLRQIQLGMALTSLCFMNQDGDVMAGVATGILVIPRADILPEKLPETNHSTAKKLPFWLEAAESNGSATMEPREPSQPTRPIGFLKKRVSVTFRDDSEDRRGFQADQNDAVNALKASEASNPESPEPSESLLPPMSPSNSWERKKDALVASIPLNKPIAELHPPVLRPISNRQPRLHLNQRPPSSSLRSPSSSFVRKDQDWRDVIMPSPYRLPTRDSPRHARTRSSAAAQTIAELRMLAHTSHLHPPRSPRRDSSCNVEDSPASPLAIGRAEGDPVPLQYCKHQAPVPHKAKTPRKLWNAIGGEDRRLLAVQRNLPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC1</accession>
    <name>A0A8K1CLC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mut7-C RNAse domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC1"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002782">
        <property type="entry name" value="Mut7-C_RNAse_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01927">
        <property type="entry name" value="Mut7-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mut7-C RNAse" evidence="1">
        <location>
            <begin position="239"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="37838" checksum="4638538B46ECD928" modified="2022-08-03" version="1">MALLRAFVRLHFEYEGQFWVFIVDIVLALSVELRQDQETRADAELTVSQTDRSRTDPKLLVEILELFHVNGITPTQVYALADHLRASKSHAALIKLCQTFLHAVEWDFHAMIRSLVQSKDWGSAELVAKTFDTSNDRDLAKLLVQEAINHQEFKRAHRIVYNFQLQADFPDIELLYSRDTLMKLIEKQRWSLALTFVGSDTTLQTLLLTHVVAAGELQYATYLAKERLGWTAFGPEQVYLTRCTECEFKGFEVVDIEYVRQQTDDVVQPIVLTAITDFWKCPLCLKIYWEGPNTARRMKTCCKCSKRQCQPPAVITPYEEKSPRLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLZ3</accession>
    <name>A0A8K1CLZ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLZ3"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="181"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58041" checksum="F966E087FAB92D7E" modified="2022-08-03" version="1">MANRKRVTSMETPDVVMEAPPLPPMSWDEQRRLVYDIVNLAPPDVPGVLLLIHGHGTAGMTCTEYPDDGITSWDASADAKRVDRLPQTQSTPTQVDCTFLLDSADQELLHQLREYVDNCYIPHYVPKENCMICEGLWSNGRVIACGNDDCDTRIHEECFGTILRENSDGPWLCPTCLLGRQLNCAVCMQSGGALKPLAAGSNTKDASDDQKWVHVLCALAIPELTMRDVPTLEPVDGFDEIENGRFRYLCGICRKRGGASIICEQENCNVGMHPICAANAGFMIGTEAKPLGAYCEKHLPTSRIAHAKRWISDVDLVEEIMSENSVIEDGDEVMGHGLERFSFILESTPGLHAQNKLLGPASALRWGALPRYSTRPDRKSNAFENVKVNANAWTVPGMVVMGLKTQKPLVFPPQDQDRVGLPVFPQGDDLVGAVVDYLVKDQDEWCRAQVVEWDAGRGLHLLQLIANSQKLWARLGSSNTQILYLMDEDTELDGPRIKLYRPVRRGVSEWRPKPRKFASASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM20</accession>
    <name>A0A8K1CM20_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM20"/>
    <dbReference type="OrthoDB" id="156202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="50"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="423" mass="44573" checksum="C4B78BAF48A46FB3" modified="2022-08-03" version="1">MLHDDRLWCLLLDQPERRHLLAQEWPWGHQCQLNNVKSALFYVGYTNPVCVLRADVDYAGNDIGRASATKADDCCDICHKYAGCRAYTWTNQGGGTCWLKSKNGGETYKVGAMSAEAYPCSQPPTPSCSLENDVDYIDNDIGNKPSSTAGGCCDICKNTDKCVAFSWTNQNGGTCWLKSAKGSTAQKAGVISSQVSPNPPGPTCILETDVDFIGNDVGSKASSSAGGCCDICRATTNCVAFSWTNQDGGTCYLKSRTDKKATKSGAISSQVLDNPPAPSCTLEADVDYVGNDIGSKASPTAGGCCDICKNSQGCAAFSWTNQNGGTCWLKSSKGSTTQKPGVISSQVAPNPPTPSYNLENDVDYVGNDIGSALSTDPAQCCTICKATQGCKAFSWSGFQGGTCWLKNSKTATKSSPGVKSGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM65</accession>
    <name>A0A8K1CM65_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003847</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM65"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="584"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="226"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="299"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="381"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="679" mass="77673" checksum="350BF2BB234D98D5" modified="2022-08-03" version="1">MVALTVANKHEKSLNDYLKKQIQELSAEISQLKELYEDEKTKNEKITALRKQKPGEYGYLPDIHSAAAAAATAAALQQQTQMEITYQRKILSLENRYKDLTENNKRLLRKIEQLEKTEADADALISELRQDNIRLATEVDSLSSTVTSQSALIIGLRTSLNKLTQDERQISTLIKKYDRSQIDLVATKVREKLIREEMERTKLIMSKEKEGLMSKILEFQQRLQQSNLAGADAEALRDSIERLEQEKTELENAMDDLRKANQKADDRLHEQEQMTNRLLQDKEGLEIDRRNLLALVATKDELLESQDELKLKLSMLRQKGSEVDRLMLQIVDLQGVNDMLNQTNSKLRDELQSMRDLQLSHDETVRALQLARQKAATHEALALVNEERKSLEDKLRTLQSEWEEERGQLVAAKKQLEAETEFQTTRIGQLQAEIAVLRGRPAEQIIVEKILPPSAEEAEERARIEADLARLRSEYSNLRENLESMEKEYNKLVTKKYKTESFQSQVRLLQNENTELNGRLDDLLREQEQDRNELHARAMEIVELRHRVMDPEAIDMLRKTQESLEKTVSTLVEAEIASESTFTCLQCMRLFVSPMTLTPCGHTYCATCLDKLGGDVSVPSTIPCKECKASGKASDIESVFPNQSLADLTARFIFRQQTLSSMTTMCLSLRNSFATRSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMI4</accession>
    <name>A0A8K1CMI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">U1 small nuclear ribonucleoprotein 70 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMI4"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001585">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="118"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="61"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="37753" checksum="5E854E5448137DE3" modified="2022-08-03" version="1">MNAHRKMTPKGQMSSSGMGPAIVHLPPHLKALFEPNPPLEHLPQLTKRKMPPYSGLTEFAETFETAQPPPREVSETPKERRERVRKEKVEAHEAQLQANLEKWDPQAADERKTEDAYKTLFVGRISYETTEKQLRQEFEQYGPVKKIRLIEDEEGKSRGYAFVEYEKESDMKVAYKQADGKKIDGRRVVVDVERGRTVREWKPRKFGGGIGETRKGGPDVNVKYSGREPINQVKVGGMRDGPDRNGEDRYRPRGGRDRSDSRPRATSGGRDRDRRERRRSRSRSRSRSRSRSRGRGRDHDRHRERRDSRDYQRGGSRGGSRRDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN55</accession>
    <name>A0A8K1CN55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN55"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="805" mass="87686" checksum="5CD5C506A9E5114F" modified="2022-08-03" version="1">MARNRDFLKHLYHVLTEDTLECLTWDPRDDARFLWHAGSDSELTAYLQVKRGRFGVSKLSSFREKLTKLGFEHDGTTVGCHPPMACMVYKHRNPSSFFRMMYAPPDQRPTLPPPTTAATGQEEMEGKLEANTVDTVTTDKASAVCRKRKLAMNLDRSRCRELPDGPQEELTVGREVTTDMQPLGGQKEQDMASSRAFSAVVVAPINSAPISQGTPMNLGVVYKRKDPSTFNYVTEEVEKPMEMRTGVALGKRKQEGSQCGSRYRESPGDAQMELDFDHHVSIDVRSSIKEGSSEMTTGTSLRPILQHSSLPSLGSVQKQTTAMYEFPSIAWAHESTPTTRDGAVDKQEVDSGDRMSTSRMHGDRDQEEKSEESAVPLSVQRSGDRIRHTQAIGASGSSLAAPRDTLAGILLALSKSDGNGAARRAFSEPYVSGATDTSSCSNAGVGDHDSASSGLSMPPLTLEQKTNLINKTDPSAVHPGFMPRTQAMASSGRYFAQPQALHQHQHQHQHQHQHPQQPSQTAPFVARSYGSLPLPPASSNSSGVTDHSRASTLSITFSSDISSASTISTASSGYYLSTATDPSYSGAYDDEDLENHPSMFMPPLTLEQRSAFLSKKGPSSPHPGFMPRRIPEGHTVTTSTGERIVFAPWRTQNTAFGRSSTNVGVNVDVGAGAGDVKATATAASARSDQDDWDRTYVSRATDGAFSGPFVESESEEKPSVPMVDSSVEKFRVPVDLANVPGFKVRYVTRRRRGSFSDAGTDIDAGSVTYFSEEGESDDDDDDDDVDPHWRELERGVAPIIADTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN56</accession>
    <name>A0A8K1CN56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2CD3 N-terminal C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129860at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057537">
        <property type="entry name" value="C2_C2CD3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21254">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21254:SF1">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25339">
        <property type="entry name" value="C2_C2CD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2CD3 N-terminal C2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="939"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1415"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1763"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1782" mass="196747" checksum="870AB632054BABE6" modified="2022-08-03" version="1">MEMAPLRASERLVQELTGCSLPPQVEEEPLGAVLLSVTHILPSTAVGGEEETTSVGIPRVSLVRVRWWGEDKPDTLFRPVRVGHDGNGRVGGGGDEEEKGEDAEEEEEETRSWIRMRYPVCAPAEQLLEYFHDMRELVLDVIDRKTRRRYEKLRYTNELMEIRALEDPDHVVGYLAVNFEVEWHAATAITPSKWVNEPSTPSISVNTAMIDHPAAHAVPFFDPGSARKRLSFSSISSSSTGGDRYDRRYTPFSSSYAQGRDDRGKVVTNTRLEELLAKGRALQQSMSQAAEYENVQVPSDPLALIADNLSPSNPVLAKARMSTMLAPYEAVTEEQDTDWQRVLDESEQIPRRETSTAEVLRELEDVSDFSHLNAFPFGISDQSIICLQGGFLILEVWVEEKTVLPSHPIATFLGVAKIPLRSFQFVFRDGKLHGLCRQISPLVGIDEDIPIANPLTGTTTGSMHVKIALGTAEQLFNLRATIKAVTKFQSIVRGYQVRQALGFPTWHLESSAQSSQLLTPSSDYDDVGSSQAVQHDTSPDVPPRMVERSVRFIQLDIRLELRGPSAQQRGFSTVGCEVHGKLRLGNEALVLGADGGLQFVLWWDANDQRLNSQFVHSFHSHNGSAMEIRLHDVSAMFQIIPQHVSKGISTGEDIGQAALDLSSLWHSSTVQTSTEKEESQTVVRDVDLPITWSPGNRNDIEALPLRVSIKIYQEDSTTDAEPTQQIVTIEDERVVTSTTIATMERLLPASLALCFDFQRLSDLKMLVSEVWKGLSTRTDVDEESRVLVRSILETGHGFLAMEFSICLGNEVHNAEKQSKTVVYDNVSRRWFKQFRLEAIPVDIVDGVQLLPSVACVEALVIVHPELIEKLQESNLDVSLWLRGEEAKTATTLPRIDLGVVSVPLAPILFRPNGVQGSFPVQNSKGFAGRLGVHLFVEHDSNDDGDARENPEESYPQNAMDHLSHPSVSERLQNSLTEAQDDVTPDSSEDNVGPGNVSIDSGDEDTAVKSEDGIIVSTNEDTGDHTSEAIEPSSSQTEEVGTLAQAVASINEATQEINLRLQRLLLSSSALVSEVEESVTSSVGMTEKAEPMPTLVDDHDREDYECKTIAVEYAGTKDDNEDGRVMEIHEIHSASASEGSPLCTMWDDDRVKSGADEDDNDDEYFQPITLASLGISEMEFSPVSVRTSASLYAVPLGVDEVTSQPSSPPIPHLTDDDSFVDQLASLSSEEENANDGGVADELELPSVFADSTENVEEECRQVEHDEVDKPTQLGEVELVENEAIKLSDNQGLCIEMPELQHDADDNALDNWNNPSTCFSEQDDSTAEEDSWDVHRGTTDIQDVEAIPQQHLHEIPAGDTEEVASATVEGYLVEDSSAVGSPINPPHVQERGEDNPLAAFVGFKGFDLSVCSSRLSTATTTEDKSTQVEIGDSVDTFNLLEEKESGETESGRTSHSVEAPSSEAPDDISVHRDHAHERNASNDNCVLEEPVAPSRLQMSRQSSGVDAGCQTEAMAVSSHEMPTANSSEQGIRVESVALPIEKFNLAWQLLSEIRSVYVDGVTPAASPLKTPEYQPFASGRSSFFSSSLVYEEKADLETDSDGHAEEEVSCRHPRQYETETTRTVGQGFDVDAFQDERYGERHEHRMASGEGYDHHNRRVVREMEDRGPSSWQWLNKEELQKEIIVRIKASGADEDDVKWSEVVSSPKSQWRSSGIGHRSSAVRVTSATSVARPTSAKRSLFKDNTETERIARIMQGSIKYWLQDSSEEEFTSDDEDEDTGAGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNC2</accession>
    <name>A0A8K1CNC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNC2"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428275" description="Glycine-rich protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="18593" checksum="3F4807F6336DD4DF" modified="2022-08-03" version="1">MKYSIALAASLAALVSTIEPISANSVAISSDAKLPSPTEALDTVKNIDLPKGITLSGTVEPIQAPASIKDAGTDAKNKKESDITDNQIVIADDKQDHQDHQEWYGRGLGWGVGGWGGLGWGGWGRWGGWGGFGPYRFGYSCGGLGGWAYPLGYWNAFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNQ3</accession>
    <name>A0A8K1CNQ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Fanconi anemia group M protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_008414</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="164902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18801">
        <property type="entry name" value="SF2_C_FANCM_Hef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.20">
        <property type="entry name" value="hef helicase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="183"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="524"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="1170"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="1225"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="22"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="868"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="931"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1100"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1349"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1548"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1659"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1695"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="877"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="931"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="951"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1111"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1138"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1349"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1370"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1394"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1410"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1458"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1548"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1662"/>
            <end position="1681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW65772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1938" mass="214572" checksum="7B4351A2AC3634DE" modified="2022-08-03" version="1">MDDEEWDDDVWSALDALETRHLQRSGDQQSRCDGLVDAPRNGGSNGALVASGGRAMTRAASASTRPPVPSVPRNPPGNGSSAAFPSTLSAPSRKPAPKHTQMRMQPAQPVFIDDEDVDDEPVDPMAAILAMRERRGGGEDPTAKTRYLDLVPRTSDLPAMDFEAAQTFVYPTNYSIREYQLTIAERSLYHNTLVSLPTGLGKTLIASVVMYNFYRWFPTGQIVFMAPTKPLVAQQIRACHEIMGISLVDTAELQGSVPPPVRKELWKTKRVFFCTPQSLQNDLQRGICHAERLVCLVIDEAHRATGNYAYCNVIQAVERKTQLFRVLALSATPGAKFDIIQDVIRNLRITHIESRSADDPDVRQYTHARQEEVIKCSLGSQISEIKKLFLRAMQRVVHRLFTLQVIQYNDPERLTKFYVIQTRDRLRQSPQYASKRGAEGDLALLVSLLHGRDLLTLHGLVGFNEYVEKLRKEVQEPEEGTRPTWAKKDLIGSTEFQALQLGLQHVAAASSTDGDTGSHPKLLKLREVLHEHFQRHATAQSSTRAIVFTQYRTSVTEIVNVLNALAPLLKVQPFVGQGTSKESKGQTQKQQQEIVRKFRQGAFNVLVATCIAEEGLDIGEVDLIVSFDALTSPVRMIQRMGRTGRKRVGKVIILVTEGDEEKKLARSVAAAKTVSRALTTFKNKFTYAKCPRMVPMGVTPQLSALAMEIPEFHASQIAGRQQKRVVTSEKEARKTKEATVDAWRLNELEKSIARAKYVLPRMPERRDFRPVVASRRVLLRRRPWDEDTKDRVDESARSRLLRSLVRRMHGVSYDDEDEDRAVRAMVDTEEDDDEPMPEREQEDEYQYEMAMAEMHFSPQYTNDVLASATPQSTEKVPSSIKTSTTKQTPPSTTTSRKKPRRSIAKTPATSTEETSVLERGERLLQRLTEMLNNSSIKGTPSPSEKAKETTPSDSETASSSGASSAATPRRPLAFPRITRRLVFDAETTTPPSSRSRENCVPPPPAVIDLSWCSSTESVDLTETEQKLEVTEPLVHEPTQDVPPEPPTWFPSVNKTEEERVEITVTLAREQTPEEPKAKPRRSLALRNLATTTPVTAVIPPVPSVPSKATPVPSTVSCPTEQVTGMPLETPKPAPVTTELVTSKRQAKQKASSTSTPSVTHVGTQREEEDDECCAICSEHESYEDDPIVFCGGCNVAVHQFCYGIPRLPTDDWFCDFCASQDGSSSARCALCPLRGGAFRRSSCGQWVHVQCYLWIPELKFKYTSGGLLSLGVLSRLDPERKTLECSLCHSTQGRGLVQCAHKRCLTAFHVSCARHGDASLVQMEQDDGQTLFLTYCRLHRGSKSVWKVPVTTEKPTTPQKQVRTEPVKPAAPSTMPSPSALLLSQPSSASASKQQRRRFKRLKRKYEAGSTPSKDPSQSSDGVSPWAKRMRRSQQFNEDARGRRQQQSALAKTMFIEDQAEAPSTDDEEDDDEEMDEADAAFINDSSQLFSPSRTSMSPGDMRAIYARSLVESPRTPALLRGQRGGYLPSNGIIQACLNELHGQTDSPLSVVSSGAATTPGGREGPPRTTNASPISIASTRDGEEEDAKVDGKEVPDGAPCFNLLGFAASTSTEALTSAKELPNKTAAEVALTRDSAKAEAEELQRRIEANRLRALEKLRARQQQQAQAVTSNPSSSRSPPLRASTMIASTDVPSFSLLGGQTPAPSPLKPPRRPSGTRVPVFVSTAFAKSHLNTMQNDEEELRVDEKASLSEADVVLSVRLAAVCMKFSELTTWLTNKRDVAQHPRVQLALQVFKQTLVLVVAEGTDSSVDARHPSFAQLHKLETCAGVEIVRSVSAMQGVLQRHARAEWTQGFGLEAPTDAGPKSALDENFRGRLRFFRDVCALSLGSALSLSFRFDRFVATQIPVHKFNEMHWRRMLPWISEATAMALTAHFHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPM5</accession>
    <name>A0A8K1CPM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPM5"/>
    <dbReference type="OrthoDB" id="166708at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="24532" checksum="FA005872037A9177" modified="2022-08-03" version="1">MHDGRTQIYKYSPFSFVVDGVNAGLEQFCKSDDCFDLYMLFRKINNGFSLLAKFQRSGSHELGFDPDKVKNALHVAHALTYMHSFQPVVLHRDLKSRNILLDNELNAKLTDFEVMMGKRYDEKADVFSFGVVLSELDLHELPYAHAVESGTGRKLPDTVIVHMVSIGRLQVEFVNPTKSEMAKVGLDCIALDPTARPTAAEVLNRVHQIWLRHQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQL5</accession>
    <name>A0A8K1CQL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PLC-like phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQL5"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051008">
        <property type="entry name" value="Telomere_Capping_Maintenance"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518:SF2">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518">
        <property type="entry name" value="MAINTENANCE OF TELOMOERE CAPPING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428339" description="PLC-like phosphodiesterase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="861"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="902" mass="95030" checksum="07FF34B346FF8EE0" modified="2022-08-03" version="1">MLGRLVRFAAVVTALCAGQAVQSVAAKPSSVPSIDSAYFLRHHERILAAQAADDQASCDAAAKGNPLATYLSGLPETAGLKTCAASNLATLMAGLTTQCSITTLTGLLGSTNAGMTAFSELFSALTAGFNSSSTSASGTDLTSVLSSWTEDSTKNAAFCSTMNSTIGPCVQSILPIFLSLLENKAACCSELVEYYELIKLIVPTGKTPAQTLFDVVNGLHLTMCTKTGSDSYCGEPLLTYVAGVVEKTSATSLLSPLLFSAGLPLFALPDGDDACSALETTEIPSRVASTDGGAYAFADLSCCATGLSSLIESFDSIVTFLTGNSLAETLNLITARQDEDESSQFKAPYEAIKGCSFKKTCTKPSFNLPTDGKSAAKTGNPSKTVQPKGLKCTTTKLCNKDNVCSSVCEAGSVKIAPWVARAISYQRNLSYDQPLCFTELPGTHNSATTFANGYGNRDQLVNNMLDANNSDSYMRTSNQIVSLTDQLGMGARFLEIDSHYFAKSFRSGHCSRIQFSFLDDASAAIVRETGALLSAGSKEDATLVEWQASLMGCLPSLSGIRAEDERLHEETLNEIAEWVKANTNDLIILYTEIGSEIDTFRKTDDLLALYEKAFGDLSFTPADFKAQGGDWKDFKLSDLIAKGKRVIHISGSSNDLMFDMDKLCDGWSDIPNGKTGTAGAIWGQKTNSGKLIRAYQSQLHYATMSEDALGGSVVTGTDSEPATVTAATLPAFVKAGVNILAPDLLDGATMTAMVWSWASKEPSEGDTAVEISAKDGRWYGVKDKSSIQHVACVSTDDRLSWKIVSQGSSCPDGFAVGAPRLAVENTALVTALQATGADATAQLEVDLSKIPTISASDEAAFEDLSESGTGSGGDSAPEPSGATSIAMSWHVGTLMAVMCTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRA9</accession>
    <name>A0A8K1CRA9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRA9"/>
    <dbReference type="OrthoDB" id="157554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="377" mass="42790" checksum="D0994327D1F97591" modified="2022-08-03" version="1">MEDWTFTSLLYDEDALLMEAIETHVTNASPFNSTQGATTSESEDDPMCMEEEAPKKKNKPTYYARKDEIQTLQAELGALTERLEEIQDTKQQDNGLDDAVLENALLRGGLKQTDLTLAGAQSIMANYRATHGRNPLDVQINLSADPTRRHQTLTALRDERLAEATDFILERVRYLDLRRPHRESESFELPNGDHVLLQCEVEPCRTNASVKLVFDDIIMAIIQQEFTVWESLGVTTTFESDESQDFTYAQTRGISTMPDGAQFEKNIASFRMYSDGSKQLNAPHGLVALHPVAQDERYPFQPQNRVRQDTTMVLMTCPLPGGGGVVTIRWAYVLTHKPQCAITRLQEMRMRDISARWNEIVRNNALEFVLGRMEQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRD8</accession>
    <name>A0A8K1CRD8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRD8"/>
    <dbReference type="OrthoDB" id="164695at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="158"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="427" mass="46379" checksum="795332FEEE601ACB" modified="2022-08-03" version="1">MSSSGSGSGGGAGNTTRFLLARGLQSSSGSSSGSSSRAGPSIGADLVAGVPTPSPTPAETSTNSQTISVVAIVVISVGIVIVGIAVFMAVVWYRRIRKRHPRTSEVPQVLNAKSASYQIDTVTRLRGSVIGQNAMARNASSLWNDEELLSYHMRIEDLMDVRVIGSGGCGIVYLVKYRESRLLASKRLVRDQSTRQKSRALVAEIKLVAKLQHPCIVEFVGAAWTTESDLQALFEYMPNGDLRSYLDKTPQAPWDERKLIIAKDIVEALVYVHSFSPPLVHRDLKSRNVLLTEEMHGKLSDFGVSRYQSDNRTMTGGVGTSRWLAPEVINASGEYNHMCDIYSFGVLLSELDTHVIPFSDLRSPQGNPYPEVGILQLVSEGKLQPSFSASCPEYLVTLAKRCLSFDPSQRPSAIEIAYVLRTAGNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRE7</accession>
    <name>A0A8K1CRE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007886</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRE7"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="902"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="932"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="583"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="879"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="979" mass="108979" checksum="D88C4BDF6BA3ACC2" modified="2022-08-03" version="1">MRSHVRTLLWKNWLLKKRHRKALALEILLPVIFIILMNGTKSMSPTVYVPPGWSDATPNPGNKTAGSSYTLTNSSGGFGAEDLEMKIGWKGAKEPRYLVRETTMSGLLLYLDMASPNAIPSHCRDNVTPYKIAIAPDTTFTRKYFLKTMKVWYPQVAISKSNHALTSQVKVPAFGGSVVFFKDEDELELYVTGENYGKTVDTPKIYGAVIFDKYPDEQAIGQATSIEYSLRFNATGQSGSNGDVPRTIGDPSFESPFQGMINTDPYSRYAVLGFMTLQTAITRFVNCMPVWDATTKSTTGACKHQMAVAKADAALDSKLFQRIGNDSFVQMALPFAFNDLSTAAIEHASISSTDKEKLLAPLRIAPQPYYDSTVAAFLVDAFLSSPFYNSVKSVFALVFVLAYLYAVSRILVAFIQEKETRSREYMKILGVRESSIILSWYITYFMIFLVSTFLQASVLTGGLFDNSSFGIVFFFFFFFSTSVLAFGFLVSTLFSRARTGAFAGMVLFFFMYFVSSAFEKVIPKEYGIAEKWYFPLSPSYWKRKYSAKINNTGVTDETVIDIDPSVEPVGQDLLEQEQTGEARIIKNIKKEFVVPGGVKKAVRGVSLAMYKDQITCLLDHNGAGKTTLISMLTGVIAPTEGDAYFRGMSFSRDMAHIRQSLGLCFQYDVLYAEMTVEEHLIFYARIKGYTKASMNEVVSTKIKEVGLTEKRKVFSAALSGGMKRKLSVAICLLGDSLLVFLDEPTSGMDPYSRRSTWEILLNNRQNRVMEGQLRCCGSSLFLKNRYGAGYNFTLVKREKCDEKQLIGFITTRVPRAKVLSNVGAEIAFQLPLDCSSEFPLLFEALDDQLETLGVLSYGISVTTMEEVFIKVAEADDEDNQHTLKKDAGSPDAVSTGPSSPSIANLTGMTMFFVHLHALLFKRFRVAKRDRRVLVFSTLLPVLLLGAGRGLLKSSTVTKADPKIPLYTEGFRFDTNNVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRT5</accession>
    <name>A0A8K1CRT5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRT5"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="310" mass="34593" checksum="4CE656B097654E17" modified="2022-08-03" version="1">MHPSQIAMELPIEAEAVRMESVPVTSLGLHGQDPHAQDQRKLFMKLLRSGVQDKLQNKTQSDGPAAAWQALSWRNAQALEPFFEETVCGQTLRVKQLLQGELTGFGTGLTVWPAACMLLKHLEHRYGRGSNSSTEASLESKLVVELGCGTGVVGIAAAMLGAKRVVLTDVQKLLFLLQMNADLARDLSGGRTNIEVETYDWGASPSARLLTEDGSSPDFVVISDCILPKLYPIEPLVEALDRLTGINTTVLISYEHRHYEQFHPKLKFWELLTARGFEIREIDQSLYHPQYYADDIEIWEAHRNSESISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRU1</accession>
    <name>A0A8K1CRU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRU1"/>
    <dbReference type="OrthoDB" id="60781at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="41346" checksum="D0C43318AE8A3B6D" modified="2022-08-03" version="1">MASIRSFSTASVSSGTSPGVGSVRSSEGCIAMSTRSGIYAANLNSRYRKELMKAAEKTCNALAQEAEHAFSIPRSRRPTQWRYLVSAHGLSLYQYGNETAAPPQPLIPHGHHVRPSSKTVPRVVALGSIHSTLNELIDLLGPKSGNSTALLNPDLEEDELVDTLADRGSVYTAIKCLRMGGSWNEHMRRQREFLVLESHRMIQTPEGRNGWLIVFHSASWPSCPPPPGHLVRGSMYRSGLLAMESEYFPDRLDLFLATKLDLKGSSTMHVHEMIARDRTVMMAKQVIDAIEQRAAARISIANTVVFEDIQRRVTSDKCDTCFDRIGFVPPGTEPYACRKCCATVCGSCSEIWQRGNKGIRLCMECWADVTLSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS29</accession>
    <name>A0A8K1CS29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS29"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315">
        <property type="entry name" value="U BOX DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23315:SF7">
        <property type="entry name" value="U-BOX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="629" mass="69377" checksum="8D5EDF34DB1ABABB" modified="2022-08-03" version="1">MPMQVIEPKDAEYPHVPTPKEHELSRQVVDLQQEKDAIELKLMTQIKDLEAQIHKLQVRVQDLSQHLQATKREQIQSEQAAIEQERAIWRVRVEALQTELDQEKNDKEAQKKWRVKFTEADNNAVVDPVDDALARFAQSIALLPASAAPKATQAGVLPFLVHLLRENFSDVVTGSVLMALVHLAIYQKPQRPTRLRSVLAPATEAICVKEEIVKAGVAAPLAHILESVRNARVLVEGARLCAALSGDVPNKRVLAAKNIVRHLIQLLLPRSDDGTPDDAMSTARRETLPLPGPSELQHFGLSALVNLAYDSEILRSQIVNFDFIPIAVRYLRESPVLTVQAEAAKLLGNLAFNHVVNQSAILTAEGDAFLTRRLTATYMHQSADLVRASAVGVGNLAYTSVNQLSIGYGDATTFLLQLLVDATQPLVLEAAAIAICGLCHQNPLNKSRVAAQNGLQVLLYVIGRSQRYGHNEAVLIAALECFAIVAKPKPARQQVMELDGHLPICQFCKKSNSEPLLIAAGMAICALIPASTERSRWLADGKEYKLETQNVALSALERVKHQVYATRTQATPSWLARGIAQLTSYASSKDPSGKVEEEEEPTEFHERSYYSMESLTEIEPDELCPGFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG0</accession>
    <name>A0A8K1CSG0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSG0"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="121" mass="13215" checksum="16A5284D1C21FBAB" modified="2022-08-03" version="1">MLEYVRQAAENAKDVLTVSTGSRTLGATGLLDGKRATTKKTEISKVTTSYPGVKWIDNERWVSDGKYRTASGSTAGLDMGYAYITARYSAKAAENIATNTEWCSIISPQFCPTQFCKKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSR3</accession>
    <name>A0A8K1CSR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSR3"/>
    <dbReference type="OrthoDB" id="1913277at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039205">
        <property type="entry name" value="NDUFA11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="14295" checksum="13F16D0A1DF11241" modified="2022-08-03" version="1">MDGPKGTEKIVVATGTGVFFGTAVGAVESVWAVPKLGAQLPKFTAQAKHIGARALVFGAVAALYTTAEYTAESVSQKTSPVNAAIGGAVAGIVPGIVAKNARVAFASSLVSAAVMTAATYWNEQSESAFDKYAKARAAEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTA4</accession>
    <name>A0A8K1CTA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTA4"/>
    <dbReference type="OrthoDB" id="10266500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="58302" checksum="7EE23F71D0C4BA55" modified="2022-08-03" version="1">MATTAARAICLARGLELLHVWEAVGAYLDHSARWTIERAAAHGHKYLVQHIAITRPLGDDQEVASLVMDFAARNGHLDILQWLNDTKTLNRCSTRAMDDAAKNGYLAIVQWLHENRQEGCTVKAMDGAAMNGHLDVLQWLHLSRKEGCTKKAMDLAAQNGRLDVLEWLDSHRHEGCSPLAVEYAATEGQLDVVKWLCEHRKMEGAPTAMVKAARHGHLATLEYLGQRFPDVFESVGAKMVHAAIANGHVALMTWLISVLPLRALKCEGDSYSWLDVAAEFGQVAILQWFSEHTSELPVGVQIDGHLPACSPEAIEKAAGNGHIHVLDFLHGHEMVEVDSQDDAVKAIQAAVQGGHRDCVEWLVHHFQRHLEEPEASTAVMDTAAASGHVEILAFMRACVVTSSWHTSAKAVNEAARLGWIDVLQWLHQHEVTGTPETSELWTPRALECAAANGHLRVVQWLVANRCTECRSSEALNSAAYMDHLEIAQFLYREVRSSCSVVQALEHAEEGGAEETLAWLESLSPQDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTA6</accession>
    <name>A0A8K1CTA6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTA6"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="51315" checksum="DC5CFBB2DC0E7071" modified="2022-08-03" version="1">MSDEAKLDFAWLPQGTEALADGEYDAIVLGTGLKECILSGLLAVNGKKVLHMDRNPYYGGECASLNLTNLYNKFKPDQEPRSDLGSNRDYNIDLIPKFIMACGKLVKMLLHTKVTRYLEFKNVDGSYVVKGGKTYKVPATPEEALKSSLMGIFEKRKFRKLILYIYNYEEEDPKTHEGMDLFTQPMSELFEKFGVDANTQSFMGHAMALMRDDSYISRPAIETVRAIKLYAYSLERYGKSPYLYPIYGLGGLPEGFSRLCAIHGGTFMLNRGVDEILKDDSGRAWGVRAGNEVAKGKLIIGDPSYFSSDKLRPNGKAVRSIFILDHPVPNTNNSESLQIIIPAAQANRRNDIYVCVVSHAHCVAAEGMYVAIVSTVVETEDPLSELEPGVVLLGSYIDRFDSVTDMYEPIGDGSDDNCFISKSYDPTSHFETTSDDVLDLYKRITGEALDMNINADSTEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTL4</accession>
    <name>A0A8K1CTL4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTL4"/>
    <dbReference type="OrthoDB" id="162149at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="181" mass="20277" checksum="2CC5B03A2F49B95C" modified="2022-08-03" version="1">MQFITMPPTLPNAGVTNMEPHAPLFPSFMTPLSDLYGANGFRVGESYAYTQDLDELDREELAFEQSVRALVDRPAPTPTGVKFHRPHGSGMATPSTTAPYPTQYQAGGPMTHGRGFGERHQDEEEEEDDEDDMEEDEGDDMEEVAEEEITAEDDDEELFPEDDEEDQEEDGSMDLSMDMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU74</accession>
    <name>A0A8K1CU74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU74"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20532">
        <property type="entry name" value="CYCLIN_CCNL_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20533">
        <property type="entry name" value="CYCLIN_CCNL_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000031">
        <property type="entry name" value="cyclin-L1-1-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21797">
        <property type="entry name" value="CycT2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="40"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="162"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="585"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="633" mass="72178" checksum="089A7EAC94AA023A" modified="2022-08-03" version="1">MEHTTMEHVVLPEAILARSPSQQDGVSAHEERDHRFWGCELIEEAGILLRLPQVVMVTAQTMLQRFYYRKSLRDFDAFRVAIGCLFLAAKVEEQPKRMREVVSVFYAIYRRRKWGKTRMTQQLLEPESDSYYLWCDWLIMVERQILIDLGFSLYTIMEHPHKYILYYIKILDGSKALAQKAWGYLNDSLRVDLCVRYRAEVIACAAIFLASRMLQVKLPMSPPWFELFDVDETALLQASTVIMELYTRKKIVWLDPLTEVNPFAIDDLPDAEPQAVRQSAAVDNVPEKPVDSTRLDDHKPPTSSTSSPSTHSSLLECWLNMEPEDELDAALIDAFDATPEPLAVLRVPPVNRGDTADVGRVRKPVDPVGIPRETVPFRQYPSFDDAYKPPNAYSTTGSKSTAVSYPSLDTVMPPAPAASQERVSWIPPRASSHPSTQPVVSAKATTTTSAPWIPRIPSPVVSASTVQQPPPLSPATPQQEIVNMTHESAQQHESVKTPISTEQAHKEQEEEEEEEEIVSPVELEARQQLLEMEVAEYQQRMEYVAQALAGLTPHQVDARRKRGEERQEREERRLAALEVRVEHQLERAHEREERRTRILERTHRSSCSPSPVRARDIKEDCQDTTQSFDYSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUM3</accession>
    <name>A0A8K1CUM3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUM3"/>
    <dbReference type="OrthoDB" id="99615at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="81" mass="8772" checksum="AF0F0796A74F917E" modified="2022-08-03" version="1">MNLDKADQLHELAPYKLVQLDSGAEDSILKAAEALKDEKIDVLINNAGIGSDEDLEGTTKASLLIIKPLTVRPVWPRSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUZ4</accession>
    <name>A0A8K1CUZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001594</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUZ4"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000199">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000015">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009251">
        <property type="entry name" value="PRK12607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="11">
        <location>
            <begin position="44"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="343" mass="39025" checksum="D7F95BBEF69211D8" modified="2022-08-03" version="1">MSLLTDAQTRTQGYVARINPSDVLTKTSLERVASEIPAFRQIVGKVRDVYVFDQYVLLISTDRQSAFDRALASIPYKGQVLTLTSVWWFHATQHIVPNHLIATPHPSAMLCKKCTVFSVEFVVRGYITGSTSTSMWTNYAKGVRDFCGNKLDDGWKQHQKLPHNMVTPTTKDDVHDELISGEEVVRSGRMTQEQWDYCSQKTLELFAFGQQEAAKRGLILVDTKYEFGVDENGKILLIDEIHTPDSSRYWLAHSYEERMAQGLSPENIDKEFLRLWFKDHCDPYNDAVLPEAPKELVLELSRRYILLYELITGDNFQFPSADASSTSAEDQLVESVRAALSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBJ3</accession>
    <name>A0A8K1FBJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4485 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBJ3"/>
    <dbReference type="OrthoDB" id="78101at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027831">
        <property type="entry name" value="DUF4485"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14846">
        <property type="entry name" value="DUF4485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4485" evidence="3">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="308" mass="36056" checksum="4C46AF4ACB48ACA3" modified="2022-08-03" version="1">MPMNRVRVAHAHENERVRELLARVQELNVHSTKHQQIRVNHWVRKLLDQPVSNPAWLKNVMEHAATLLQMMLTGVVEEPFVKMPPQGPLPSLPRHKVARLVTRSGSSSALIRESDRRLASISKARPVFHPTSRPAPRQMAKDIDDEISPPRPKRMESKQIQTTVDDDHWEWQRVWKGAFERMQRELKERNAHVQTLNEEVKELRKVIMAQERSLDQEARLRDDLKIKHRAEVENLKSLHELEIEELKAKHKKQIQAATLQNEDVLRRCRREKEMGGPFNMQSDNYGEFLAYIDDFYADTLHLTKTQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCB1</accession>
    <name>A0A8K1FCB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCB1"/>
    <dbReference type="OrthoDB" id="73523at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="280" mass="31180" checksum="9BD3D2F9C7879551" modified="2022-08-03" version="1">MAQWSKPVIIGAASAVAAAAVLLFALTSRSAKSDKSSKKNASDDDVREVPNLHKDQLLSILETICSQMGQVVMQLAKLEAKIRQESSQSGRALPEDQLASYLMGQFEEAMKAIESQVYAKFQTTEDEVKIATEYYEEQEDKDVVNAVTKLQDLYRVMTGGGFSDVEVPEDLTLEKFIAIMHETMESLNVAMEEVCLEVKELNPDNKEDAINQRYVKRADALSTEIHAKHGLTREVLQAAMMKYQQEPAFLMAMTELQQQQAERFAAAASIFNGEVNMGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD04</accession>
    <name>A0A8K1FD04_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD04"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="155" mass="17644" checksum="CB76593AC516FC08" modified="2022-08-03" version="1">MLFLFQDGTTKDMLTLSKNRESLKFSQNIQRMAVRLSIPHINMVLSIVGCVLCGVGVVAVILYSTFTTKDPLQDIDRAHVIAQVMLDESKFPSMVLRRHLVDLLDDQTKHPEVHMFVIQALALAPHECRDDKEHIKFGMESRETRNSSSHVLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD75</accession>
    <name>A0A8K1FD75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013168</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001374">
        <property type="entry name" value="Pleiotropic drug resistance protein ABC superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="610"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1097"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1136"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1171"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1209"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1239"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1327"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="107"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="764"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1357" mass="152976" checksum="32F7FA1637940C9B" modified="2022-08-03" version="1">MTDKQDLLRAEETEEVPQVYRSLNFKSIQDPYSHREDDMISRYSTIRAENLESMLSGGLERFYKKYNHLSHKINLQLPTPEVRFENLSFSVDVPVAQKAAAQYSVGTYLKNVFTPWDRPPIQTKQVLHPMSGVIKPGSMTLILANPGAGKSTFLKALAGKLKNSKKTKLGGVITYSGLRGDEIDLIKLAGLVDQRDNHIATLTVRETFKFADLCMNGYPEDQPEEMRDIAALRTELFVNILGLHNCSDTVVGDALLRGVSGGERKRVTIGEMLVGGQSLFLCDEISTGLDSAATFDIIASLRAWCQTLGGSAVIALLQPTPEVVELFDDILMVNEGHLIYHGPRTEILPYFQERGFTCPPRTDPADFLIEVTSGRGRKYANGNVEIPKLPITPEEFNNLFCQSSIYKKTHEHLSRGFNEANFEKPEDFKKAKAVANLARSKDKSEFGLDFFRSTMLLLNRQKTIWLRDRPLLWGKLFEALIVGLVLGVLYYDCDPKYYLRMMFFSIAVFQRQAWQQISIAFLLRQVFYKQRSRNFFRTSSYAIAESIVQVPVNLSVAFVMGTFFYFMSGLTSSFEKYIVYLLILVSYQHAIGAYMTLLSSVSPSITIGQALAGISVSFFLLFSGNIILADLIPDYWIWVYWFNPLAWALRSVMLSEFHSDRYTSAESNKNLDSFSISQGFGYMWFGIAILLSYYFLFTSLNALALHYIRYERYLGVSGKATKTDADEVESAYVEVATPTAGLKGKDAAAARANGGGLPFTPANLCIKDLEYYVTLPSGEEKQLLRGITAHFEPGRLTALMGATGAGKTTLMDVIAGRKTGGRIIGDIIVNGEPKNPDNFSRITAYCEQMDIHSEAATIYEALVFSANLRLPPNFTYEERMNLVNETLDLLELTMISNELIMNLSVEQKKRVTIGVEVVSNPSILFLDEPTSGLDARAAQIVMRGVQAIARTGRTVLCTIHQPSISIFELFDALLLLQTGGYTAYFGDLGKDSVVMLEYFASIPGTEEIRPQYNPATYMLDVIGAGIGRNVKDYSVEYANSELNKQNRVRTLELIEPSPEFIPFSTLKFDSIATPFSNQLKELAKKQRLTYWRNPQYNFMRIFLFPLFAILFGSTFYKLDYNSIKKINSHIGLIYNSMDFIGVLNLMTVLEITCAERAVFYRERMSNYYGPLAYSLSLFFAEIPYLVVVIISFVTIEYWMVGWSSYAGDFFFFLLVFYLYTSVCTFFGQWMSVLTPNAKVANVAVGALSCLLNLFGGYLLPRPQMKDWYKWIQYIMPSAYSLPALVGVQLGECKADNIACRELPDATGKLVLVEKFVHGEYDFRPGSMYAFMGGLIVFWVVIQLFIYLTLKYVSHLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDG8</accession>
    <name>A0A8K1FDG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDG8"/>
    <dbReference type="OrthoDB" id="119777at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="449" mass="51099" checksum="E09252EFFC9824A4" modified="2022-08-03" version="1">MEGFLDHLESAHRFSGLTQKKNWTRRFFRLNAAFHLLELFSDATQGDRKGKIELADAIVVSADDLGELLFASSTSSPDKPNLSSRLSVQNSRRFIFRVTEGAKGGNSGGEHHYLCAEIEGDPVASRQYMAQWLQALQTVTAHGSASPTSSSVTPMDQRELSAKIATHMDRLHVAMHVTKRTPDPHGKGKYELSIMAWTLQRELSEDELTGSKDWQVLEYSCEWAVQKTSADFKAFDAQLRQLFREELRDLTLPTISHVKTLLHVHNATQREAEDQRRVERYNAYVQQLMCLPAFSAFGSDASAMLDHFLSLSSHLVSFRRLEKSTGQNLQLRKKRVVPWLERERFVHLYQLHLEIARAQQSRKPRQSHHAVRLSSQSERSQRHEHRQKKTSKRESRSIAEVTGPEELSEPVLVESVEPTMVETDSVHDRIARIGRKLIVEAFQATPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEE9</accession>
    <name>A0A8K1FEE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEE9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25978" checksum="EE2F015DBC886737" modified="2022-08-03" version="1">MQVICLLYTSTVAEKSVSFFCAFIGFVTLVPFALPSEDLHDHLNGISEVSPTLTFIIQIEIIGLDILRKVRIRSLHYLTIVAEMFCLFGFFMMIKSVVAICRPNFNLEVLEPLDSIMEDGGLFFVFVFRFYFLAMSVGIRGVLRTKSLELFAYFLFVTHDYPWDIIGYYPDASWEPAAAMWMRVTMMMCIMLTIRDKLQLEVSHNSVAGPSKDVSLKSPPNKSMGPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX6</accession>
    <name>A0A8K1FEX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_004995</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX6"/>
    <dbReference type="OrthoDB" id="10261013at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040016">
        <property type="entry name" value="XPO6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21452">
        <property type="entry name" value="EXPORTIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21452:SF4">
        <property type="entry name" value="EXPORTIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="34"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW59926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1176" mass="132115" checksum="FB5C0E901230AB18" modified="2022-08-03" version="1">MSHHGATNELIAQVEDALRRIMDPTTPTPLKTQLETQLTEFKAHVPTCLAVLYQLLSSSTNEYALWFASTTMEEYVATRWRQFSVQEKQHLRQFVWEYVLAQGTSTTSGRPQHAFVLRKLRKVIADIARLEWLISSNGAVSPTTASALWPDFLSQVEAMVMETSTRRTGLEILCVVAEEFGREDALVVATSKRRAKSQLTAQLPSLLALLSTILNGCNQQFQQESNPAVLQEQDGIAQLALETLTHLLSWAPVAEAMHDGWIPLLFELSASWQHVRQRGGNVGPHLCGSSLVAMQVLIELMSKRFQPGHTEAIVGQTMMGLCPLVQKTVEDNMMSVVTPEFLDKLTEFVEAFLTQHLKRLEHPQYEPILPQFLELVMRLTTRQPHVSGFLNCLSVWEVFVGYIEEAEQNEAASNEHVRQLLASYERGLISVMFHLLDRVNFATNEAQLTELGDDDDEESAAKANDEAGTSFDVDGDIGDGRYVTGSLQDLAQWWASRSNSSDGAGVSVNVELSDWKEFVVECIALIRRIAAFQSCAPPLLERIFQRVKETCENLVFRLHETPSLPPGSDAWTQERYTIRDLTVNCAILSSVCAQHYCVSQDVNDQTAGWQILHMFIQLSEYLTQNRLHTRGDAFVGLQCESLTCIRFCLTCVPYVMQSGARDDVLKSTESVLQVLLQTLDTTIISSPQIVMQNAMQLLANLGYVLPYDDMISLPSMVQLEANIHQFSQHLPLTIQGDLYTSMSNSILNSAISLRNSGATNEEAMQRWANAYGALILPIRESIDQSAIAVQQNEHRVLEQIMITQFQRDFYLVRCLARSVELKPKIAKDGFCSAYQQSFPSILSLMTTYFATIKKTALGNSGSSPRARSQVKNALKVVNEIVRLYAQMLKSIRKEMQKETVGEIMRTFVEIFGDAQLSSILRQRGTPGLMVLCGFLQLLKIVVEEPTSVFSSFLQSVLELCYGPLKEAIFDHPESETIILGYFVSLVEQILEKHYRFFVSAVMTPDGRRERQFSSDAAHSYFVSIFQSLAAILTREGAQGGSEREALSPRLCRQVLTLLDRIDNAHKAFTFNGFKDEIRLGFLSTLMNILTKGEMNLLQDEIIALIHRLAAVDFQSFYQVFLPTYQNNMLTPQNIDVARSFGEGTCLQWSGQVDLPTFTQEVHSYLNDLRVIKAQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFE0</accession>
    <name>A0A8K1FFE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFE0"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071709">
        <property type="term" value="P:membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055091">
        <property type="term" value="P:phospholipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097035">
        <property type="term" value="P:regulation of membrane lipid distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF4">
        <property type="entry name" value="TLC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="58"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="265" mass="29615" checksum="C1DD6ABD498CFADA" modified="2022-08-03" version="1">MLTEALVLTWFGMCAAMLYTDPRLWIVFASSIAFTFARVVGAPLVAKQVKAFSVMSDNNQLLWSNTIVSMVHSAVSSLLALSALVVGHSLFGDFVNRASHMEFVTTAISTGYFAYDLWDYVLNRLYIKSPGIVAHHVVILICYISALTKTVGVPLLSLALICELHSVFMHLRKLMSMSSYRLDLSSSYRLVWSLQWVSFLLARVIPHVAVMLLAYQGRELFSNTWFFAMAFCGIVFINALNTQLFLQVQGAYRKDKSLAKATKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFQ3</accession>
    <name>A0A8K1FFQ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFQ3"/>
    <dbReference type="OrthoDB" id="101217at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087:SF161">
        <property type="entry name" value="TUBBY C 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="212" mass="24270" checksum="FAD9E8F22EE8B6D2" modified="2022-08-03" version="1">MGSNVSSEQHQELLRAPVTEPATPVAGVNVRFLNPTTVNLHLKEKSWDDFTIRDVQTDELYFRIDAAMLSMSQRKALLDANHLPVAQLKRDPTSFITHHFEIFEDEACKRLLFLMQSEFSMFKSELSLNFRNRATGKRCQMGVQGDWRAHHAVLWVDVGDGNKTVVARVRRPTDTFRNLVLNHQDYYIQIAPNVDLALIVLVCVAIDESFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGS5</accession>
    <name>A0A8K1FGS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGS5"/>
    <dbReference type="OrthoDB" id="59491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="79"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="274"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="482" mass="54077" checksum="2BF56BD688E75C13" modified="2022-08-03" version="1">MLMKVRTGLLDEADFATSCPDVSPHPLEMDAIWFHVNKAKEQLDKMRSCIINTLDMVIQSNNLAATSNGEGFISPGPVNETWFSDSLVPVDLKTAFVDQVSVLEGVPDKEKDWHPGSDNQVLDLVHPSLYCCVSGKTKRMAESGVVRGSSVVDHMHHIAFKATDVVYPRSTVCSWSNDVCQWIPSDVAVDKNGHVKFLSYINNLHPEDHAAMYDSIASICERFVPLFDRVLSALASESERGPQLDTSCDRDYYSENDMTNEHIPSFPDAPKRYIAEIHLTPEKPQYPGGSWHIEGSDSENIVATGLYYFGCDNITESKLSFRVIVQEPDEVDKDTLSMAAMYGLRRDEMLVQSLGAATAIEDRCLVFPNTLQHKVEPFELADPTKPGVRKILAFFLVDPTKTIPSTSVIPPQQEEWLQRLVAPMLEAKGLPVAAMEEQLTHLVSDGMTLEEAKRFRRELMDARRSESNFDDNEELYFSLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGU3</accession>
    <name>A0A8K1FGU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGU3"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16015">
        <property type="entry name" value="LTA_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052701">
        <property type="entry name" value="GAG_Ulvan_Degrading_Sulfatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751">
        <property type="entry name" value="SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751:SF3">
        <property type="entry name" value="SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="399"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="841" mass="94770" checksum="FD0F4E7AC4CAD669" modified="2022-08-03" version="1">MTLRSCWLAVAARVDAGLRPQPARHWFVAYAVLLPFFCVYRCVGFSAMMEVFATKEQDSFATKLAAVLLGLLEDALVVTYLLVLLSLVDYCVGPTVTWTQETTTSDEAKGEAPSRRRGLEWVRRTTRFVLSAGLIVFSLVPFTADILLLRLRGMRFTFEFVSMYIRELSFTQGVSVAAREVRLATHSIIVTVLVALVLVFMHMVWLDFARWNPSHLFQWKSTSPATEQPNLDDKMLENEASASPKYLSLEDGEQASTIGDSTSHSPAADPYSNVASTDNEASASRDTKLNKFRHIALVVLLTVLVLIIPTILLLIVTHNIPAVTSALALNDTLNELFRTTLDVQFLPGLGDGTIESAAQYLNSDTETYELFKDDVLYRKTTGFKGDLAFNLSVDAENPPNVLMLVVESFRYRDSLYMLGNSSTATLVEHNLTLTPNFDKWAKRGIALRNFWSSWQTSRSLESILFAQVPYDHSLNTGTTGGRQGVELNGMPQFFSAKGYETTFTTGCRLNYDNWDEFLASHGFDEIYGTKEFKAIAERDLGVKPTDWKQRDEGGTGRGMFWGVHDDVAFDVLAGIMVNKTAEQRERMQKKEPKKPFFLNHYTISSHTPWTELPDWFRKHKVPNFSPLFEGHQDQKEAIKRYATLRYFTDYTLGRFMDKMEQAGVLNDTIVVIVGDHGQSPEFGLQKPEYDQITTTRVAGAIIAEGRLGKQAGLVLDDTTEHYDILNTLADIVGVPEGGFVQSGVGRSLKRVIPEGTRPVWSNNPLRQLSVVRGHKRLTYDRRFDMMALYDADNDPSEQNDLFPSLSAEEKAEMKALRESGRRLSQYFKHRWDSKCISQVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGZ2</accession>
    <name>A0A8K1FGZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TNase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGZ2"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="4">
        <location>
            <begin position="77"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="244" mass="27727" checksum="39C61CF3B28C3153" modified="2022-08-03" version="1">MKLPEEWEPFLAEAKQTCMQQSNALIQYYHSLPHEAHVMGAFMAGICVGLLLPKLRQPFRRFQTVDDIPMSFFHQERQLSATSVSISDGDTFRARHLPFWRGAGAYKGKLSEHTLQIRLAGIDTPETPKFGNPGQPYGEEAKKWLADALDGKRLTLTLLHKDQYSRAVCMVHYGRWPFRKNASEEILKAGLGHVYRQAGAVYGGRLVVMERLEAHAQKKKLGMWKQGKKLESASEYKARLRSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHA5</accession>
    <name>A0A8K1FHA5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHA5"/>
    <dbReference type="OrthoDB" id="269173at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="101" mass="10734" checksum="3EBE254392EB1163" modified="2022-08-03" version="1">MSVSATMESLTVASASIYWWKIGACSGATAVMCGAFGAHLLPALHQHYHLLHSVVLLTVPMSKHPSVSGGHFVAGFVAASTRSFSRARTNWALSHLLEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI64</accession>
    <name>A0A8K1FI64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sphingomyelin phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI64"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09078">
        <property type="entry name" value="nSMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017766">
        <property type="entry name" value="Sphingomyelinase/PLipase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF23">
        <property type="entry name" value="SPHINGOMYELINASE C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="533"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="843" mass="95262" checksum="373A847BA1FC475A" modified="2022-08-03" version="1">MSADVVMAPPSAPAAPTRPRASTVSVTRRWSLQDIEHVDTEDAETSYADSRRAPHKHDEDDDEEEEDVFEPSSEFVCYGDRLCLLCEGQLLALTRKFNLSYEQMALLAMSTLCTGGLMGIASFFIWQKGWLRKRYAALFSNVLYEDDAMNAAKRSKEAEESSRAVMFRIFQYDPVTQSIAFQSLGQPVRFDEPIVIVHAASRRAMRYISHRGAITISRPPRYPLFQRHVKTGLAEMQRTMLRGNAEENEQERADQARARPHSVSGTILQALFSGRRERLPAPKPSTPPLPMPPSRASLYSTESATKMSSTNTSTSQLPRLTAGPTSQPVAREPSSVTLRKKSRHRSSSESCLQRPRREGSIPTTGALFAALKQRRAIKKRKQQLTKNLPNMWFPTKSGELFVATLRPVGRPCLKQLSLQDMEKQASENDDGDDPTSHATSSTASEGGEPLDDGTDEEFLRWGAPMQIVAAHNHRACGFRSREYYRDSQRYLSTDVSPTTMIPIPENGNLQAIAKESIRLLAHLERRQVELQIGTYNVWMLPRKLSMFTNVSPRKNTRARLIADVLPDCDIWVFTECFDHRARNILLDRLKTAGYCFSSPTVGHKQRDRDGRYIKKMLNGGVVLVSKYPILSIRIKLFQDVSAGSDKFADKGVLYCKILKDGLIVHVFSTHLQAWNDTASRRVRKTQLQMIASFMASLGIDDRNDAVVFTGDLNVNYWLNPENGEYDEMLDILNVHDPARVRTQSFDNVNKEATSPSSQPTTQYSFDPRVNPLAAGGLSSDGSLELLDYVMYSRSFRQPSKAESWVQPLMTKTPWTWRKQPQHHLSDHFPVLSTMTFDLWRENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIU3</accession>
    <name>A0A8K1FIU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sucrose transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIU3"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="52216" checksum="C9DDF0C484E72821" modified="2022-08-03" version="1">MSTTNKDVEAGTPVYEQFGSPKIDGIQDSEPKPRVSLGMLLLISMPRMVVQMAWSAQWAALGPYLGTMLPRFAVQLTQVIGPLSGILVAPTIGVLSDRSLNKWGRRRPFILYAGIASVICWILMGFTRQIGEACGDYGDGSDGTPTSRTWTAFFMVIFYTWMDITVNVVQAPVFLMIADFAGDRQTTGAALGQGWSTLGSILISGYIEIFGAAHKSLGYFLGMLCVIMIISVTLVCVFVKEEPLQETDAPKESTLKQIGQAFKSIWIGLKALPMVLIVYCFIFFCVQYGHTAYNGNKGQFFGIEVYGGNPDNADQCGDKCTEEQDAYNHGVRVAGGSTDLIFNSVGYIYTWALPFIVHKIGAKWALVASLIPQALLAVMAFSDVVGLNVFIVVISSLTQVIIFALLVPIVVHVFGDKEDIGVYVGALNSANCFGQLLNFAIGAAIVDTSMGYKLPVFIGGIMTVIGIVVAIFFFKIKMYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJH8</accession>
    <name>A0A8K1FJH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009103</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJH8"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="MSP" evidence="7">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="7">
        <location>
            <begin position="385"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="562" mass="62065" checksum="2D1B8981F3F0B8F8" modified="2022-08-03" version="1">MAAITASVGVNSSLLLAPSHALTFPLEPSENGVQTYLSLSNLSTRKSVIFKIRTTNAEMFLVKPAQGVLEPTGSMTVQITIVPAALNRLFGMSPMDRANMIERFLVQSVDRSEDMHVHADDLNSFWKRIPTEVVTNKKMTCHFVDAREVNTLVPLQRFRSQQQQQHEQQRTLARKQSTAQQEPRAPPPPVIAVQVPPVPVEMTPQEFTVEEYDLDEDSDDGSTSEEQEQTPEPLDFRPPLPPPRAISVTVAPPTPPLPPPRSPSRSNSVAALSQAPPLPPPRSNSVTSFAPPLPPARAPPPPPPVADVPEAPPSPVAAPATEAPATPSTPPLLVAPAPVHHEDDDDEPPIERMSQFQFVEASEERTLKPPPVPKIVEEVVQDEREYRVHPSDMLVFQVKHVSNERIEGLSFFFLTNKSRLSGLAYKVKTTNHDGYFVKPARGVIGPKSAQRIDIFLHDDNPKTFDPHQREKRDRFLVEILYLEAGVYRDLMTQRDDQPKQTLQHLWEIAKSEDKGKTMLKCEIFFDSTSMIPGSGLSDAPGVANGDGPSSIEGSGGNRQFHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK52</accession>
    <name>A0A8K1FK52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">START-like domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK52"/>
    <dbReference type="OrthoDB" id="101985at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="44811" checksum="8BFF6938A48782E9" modified="2022-08-03" version="1">MKTQRASQALPVVALTSGEQHSLIEEAAGVLAETLRVEREFREGHAAFGSKQWKEVYSRDAFHVFKERRPKDNVSGGFIAGGHREKQSGIVAAMKDPRVPMIVGAGHVEGQLEDVCFGSLASDDVSWRLRSTYMKDKFAEARIVATVHGPTPEEPYRFLGVKWFMREQPALIGMFVQFRDYLVTEAIGHAVDEQGVPYGYYMIHDFKHPRLPELTELGIIRSQISLCYICRQISPDKVHIFARGFVDLKGDISTNLTATLSAEAMSSTVNSVETSYAKKLSWLMVQSQRQRQQQRSGMGNQSKFCESCGKMGGKLMSGSLSCCQVCNCMYCGKCSVQRKLVVDVSGGGVVDHAFSFCFSCVLKAKQISPRDVAIDTVVRNANRMAVPMLNKDSPSIASLATPTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKE1</accession>
    <name>A0A8K1FKE1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKE1"/>
    <dbReference type="OrthoDB" id="151678at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="40616" checksum="1EC23390F2814490" modified="2022-08-03" version="1">MAAFLPTDATRTSSESDDEAARDGDVTSPKRKKPYKSTYYSRKSEISSLQSQIEALTQQLERVKAHQPVTAVDVYRACSENAVLQDRLQKSDLFIARTHSLVLGDMATNPRNPIDVEIRLSTNLEERQRTLNGLHGPVLDRAMRYIFERTHHMRLDQSQRQTHMWTEDNEDQVLVQCDVTPFPDVTDLKHVYDNIHLAIAHQEFQFWEHLGVTTVCHFDDPEDAPAKQARYISVTPYGIDLEKNLIRFRQLFPSSKYLDSEHGVIVLQNVDVDELHPYDPKGRVRIDVSSVVLVRAFPEGSPKPGVSVIRWGMTRVRLPECPLTREKQHELVDLIPRWGEVVRRVVKDYIQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKR7</accession>
    <name>A0A8K1FKR7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.182.10">
        <property type="entry name" value="Toxin - Anthrax Protective Antigen,domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044801">
        <property type="entry name" value="Filamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001298">
        <property type="entry name" value="Filamin/ABP280_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537:SF8">
        <property type="entry name" value="FILAMIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537">
        <property type="entry name" value="JITTERBUG, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00557">
        <property type="entry name" value="IG_FLMN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478482" description="PA14 domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="1876"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="8">
        <location>
            <begin position="539"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="5">
        <location>
            <begin position="777"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="5">
        <location>
            <begin position="811"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="5">
        <location>
            <begin position="929"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="5">
        <location>
            <begin position="1037"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="8">
        <location>
            <begin position="1231"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="5">
        <location>
            <begin position="1628"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="8">
        <location>
            <begin position="1716"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1876" mass="204097" checksum="04C207964CA7A266" modified="2022-08-03" version="1">MGPSFLTGCAWLLCVCDAYRILSSISDPLAPTPAVFEPYVRGQVGYYGDPANPDPERVNEGSPFSPDTPRIYLYGAPKQNCPGMVGPINDEEYYCHSRDYGYCDRRSGLCVCNQGYTGVDCTQCKPSYFMKGRLCYPKKSCPNDCSRAGVCDYETGKCTCALNRRGDDCSQVYCAFDTKCTSCTSTQCLSCIEGFYVDPTTQTCASCKKYDPRCLVCDATQCLECADLILNSIRRSGARLVDTALPTDELSREFSFKFSYGSQDPRVFDEAEAFSLLKSPVKYLNENSQRCVQGTRSDATWVCETTTVSHRVCGHPGVFSFTSPIYAVPETAQTIMLTVRRSGGGMGSATVAYELQHITTSAEDVSPTAFYTSSQLLQFADGVVELSFLLTIHDDHKVEGDETFRVILRSPTDGSSLGSQREAFVTILDDDLPLTDAKLSYIVPTSGTTLQKGGYAGDPLKFQIQAVLGNGALKTTGSDLFLMESYVADEREADLADALMSTRYRPKMLGQVVDNTNGLYTCSWQRSLAGEYTVAVYLLYPNGLQGDYFADAWLSGSPAVSRIDRQINFLWDNGPLFPGATDYVSVRWSGRLKPKMTADTTLFVDCDDHVRLWIGDLLLIDRWSLESDGGVAVQATIYLDSTILYPIIIEYRDLAGIARISVQWSTASLTKEVIPASQLYTAQHIQGSPFIKIPILPELSASPTATYLQGTFQTVAGTPLRLKLLPVDQYGNPRAAFDPAVDRYDAQLTLVTDQSLGGMGSKTVACSVSWQGVTRLFSVRCIPFFSGIHALDVQINGVKITGSPFQVTVTPNQMHPARSVLSGSGLVANRISGVATTVGLETRDLNNNRIYAASSNVRLTLRAFHTTLSGIIDLGTVVDNGDGTYTFTYTPRKVGTYLVHIKQNDVHIHNSPYSVSVVQNVPAGPTSVASGAGLSAATTFIQSTFQVQARDLNDNDVKTGGAIFKVTLDHIANGTQVIGSCVDLLSGVYTCTYTPQVVGGSRLNVGLLSGGVVAPVRDSPFSIDVIAGPALGSFSFARGTALVSSIAGERTTFTVFIRDNYGNDKLNAGTEVISVRFTGPSPATTNVLAADTGLQIKYVSNGQFEVSYRLERKGQYAIYVNVDGVAIVGSPFTMYTYPAQASYTTTSIDLVTPSTPPIRYYTGSTVVTSIASRDAFGNVLETGGNLFQFATSFKNSTLIDSSIFVDQQNGYYRFEFTPRIAQDYDLAQRLMRPGGLNGSYYGNPELQGALVLDRVDSIVDLDFGVQSPLSADQKETFSIQWRGYILPRYSEVYTFHVNVTGGARVFVKEAAVISELWPVAARSNAIGTFYLIANQLVPIEVQFSKPKSLTTANIRLSWSSLSQIKEIIPSDRLFTGWSFVNNVPPVHVDPGPPNGPSFTPEFPITTMLGTNTICATAGIAYTFQVAARDRYGNRRLGGGDSIVVIFPQLANAVSITPTVQDLGNAVYTITFTAKLSGSFTMVVAAPTAGVDASTNGGVDALVERLRPFFIQQSPFTVVVQPNQALGTTSTIIGDGFYTATAGIPAFFVVELRDLYSNLIQDRVAVSNVVIQLRQVADPSIIFIVNHGNAVDGKLQTNYTALATGMFRVMLSTFNGPFAEKTATLRVFPNLASALTSTASGTGLGPQVQASQPNSFQVDLRDFYRNPMEVGGNNLAVTLRGPGTVYADVNDLNTGQYLVQYQLLAPGTYELRTVLANPGHGLVGYYYENTRFSHVALTHAAQWVDAVMDFDWGANQTMRAYPRIQWRGYIKPQYTERYTLILQVYPLGAVYIDNSPVIDVLNTPVPGAPQVVEGSVNLVAKRLHRIVVEYRSPSKREITGHLQLQWRSASQSQQVIPTQALFPDGQELQPRYTIQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKU4</accession>
    <name>A0A8K1FKU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKU4"/>
    <dbReference type="OrthoDB" id="265776at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="1"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="756" mass="84876" checksum="B290FCCDC8D065DA" modified="2022-08-03" version="1">MPTVLDAVTPSDLKQAVAAQFPHLSDGSQQDAQEFLSSLLSCLSEELKRSPIHQEGMGDADLLSPSVFARFASFSRSSELTSSSKASQDVAVTINDSDGRPDTVVAKEWWIAHLLREPSIITALFCGQFKSVLRCSHCGNTSTRFEPFSSLQLPLVDETAMLSPRKKPQRTDVVVVLHFLGHQTPRRLVVTSGLDWTIEQLLIKLQETHATFSTAGHRQDHVAVQLNGACIDAVLDPDALLVTLPTPINVFELEYQTLASQTSTPTPFVVNERVLLQETPERWIRAVITRVDDSHVNCTPRSPVGSQSLPPLRYHVCLDENVHRRQVIVYGQELRPITDDRFLFLRFVHRHRGLVPFYATSPFRPMLVGVPFIHRIPASKATGKALYRAIYYRLSRYSEGSKWSQRAFVLRRVSCDGKCCDRCHWTTNCTGCPIDRSDESPLDLEIDETIAIDWAEVNSTGISSPGDNEDDWWVMMTEVEDDPSYTTYRESQTQGLAKSLKMLCAEEKLEARCSRCETQDTHSETAESTDQRQDTPRGFQIHTKSLTLWSLPAILVIQLKRFELVDDGGFSWQRLNHSIDFPINVLDLSPFLAASEASQDSGRDAAQVTKAEAFLKARLQFPTDTASRDSTSYRLYGIVHHMGDLGGGHYTAHVRHPESGDWWLVDDATVTPARVDQLSPSSSAYLLFYVRDDVDSCMEGTLLSPRHQIPTEWYPPQHGATRVSDHVIEQLWNQLKTPAMSSKPLGQPNENKCVMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLC6</accession>
    <name>A0A8K1FLC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLC6"/>
    <dbReference type="OrthoDB" id="113054at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22552" checksum="C3A8C7F181E50263" modified="2022-08-03" version="1">MSFSPVSSPSEVAQFLRLMETATLLPSPSTAPAQAQLTTMQVIETVAIRESVKRNGHRYYLIDVYFKASSRSPTSVQGIPKKPSLQIQRRFSDFMSLRYEIYHYARQRHSHGNVPCHYCAKIIAHNILGRGQPGLFTKIVNSEDSTRRLLDQFTKKIVDLTLRTSTAREPECAGQKYIPLVVSRFLHPDEPSNEEGTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLS5</accession>
    <name>A0A8K1FLS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fanconi Anaemia group E protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLS5"/>
    <dbReference type="OrthoDB" id="3247158at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043240">
        <property type="term" value="C:Fanconi anaemia nuclear complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039685">
        <property type="entry name" value="FANCE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021025">
        <property type="entry name" value="Fanconi_anaemia_gr_E_prot_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32094">
        <property type="entry name" value="FANCONI ANEMIA GROUP E PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32094:SF5">
        <property type="entry name" value="FANCONI ANEMIA GROUP E PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11510">
        <property type="entry name" value="FA_FANCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fanconi Anaemia group E protein C-terminal" evidence="2">
        <location>
            <begin position="260"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="52139" checksum="28CEF188AE3A84AF" modified="2022-08-03" version="1">MASKDAVHGAVVAAKTRGTEGLYVYLQDHRLELPELLTRLTAPALLDATTHGFASGTGDVGLKIEVLSPRVQRELWSAFVRWKTMLPPQELRLLVERFLTVAGSPDRMTEADSVCVHLAQLLLPTEEEHDEEPLDALDAQLGQLVWLPSMQPYRKSTKKIHIAGDDSDDLSQSRKRRRSGDGYSTEDEDPAASSSQARRPKITLSPELEQRATTIAKQMEQVAAPDAVMNQSKVQQVSVQASELLQQVMNAVETTAAENESMFALLCTKLQLPSTSDEVLFHLTTALMEGNWSAQYAQSFLQAALLPRVLAATSVISRVLLQTVLLYAKPSYQTALIDGLIVPVLSTSGISSAQGEALTRILREKGVAAEQLDTLVNQSLSQSTSILANEAVVLVFQSVLNLKPSLSAATIERLITVLNGSVENEAEILKSAKFATLLFTLVSKYGEQCAAHADDLEAVATKLTSVMAKAALRAIQKLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLY1</accession>
    <name>A0A8K1FLY1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLY1"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF17">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="419"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="565"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="578"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="609" mass="68215" checksum="1A7F43325E66D247" modified="2022-08-03" version="1">MQLVESLPLPRVSPATSHADPMSAAAEDAASPVAPTSTPLFQLQAHPHPHPHHAGHAHQHGPHCSHGARPPVPIHAPPAPPRDLSPLDELFFCAKTNHLVRFQELIGLHGATLAHERDAQGHTVTHWIAQKGSSELLEFVNSIGAPMNLPSEDNVKLHPIHWACSTGNLAALKAFVRLGVDINTADATKQRTPLLIAAQNGFPLLVMYCVKQGADINLVDIDQDSAIHWAAYKGATEIVSVFQYLGLSTDAPDRYGQRPLHLAAMRGELATVQYLVEALDSDLHATDQQGRTPYELAKLKGYDRVAQYLARRQFRRKWNVFTWWESSRAPFYFTSVNFALGLLAVWHVVMPAMPELRGLYVLLLAWTLVTIVFFVQTKRTPPGELADDPQYQDEYSHVTEALVHSDASTNADAVLLERPLCHTCHIQRPLRAKHCRVCNTCVPLFDHHCPFVDNCIGEANHIVFLGFVASLVLDLILLEYILYRQWSAQGFTWWRLIGVGYALFLLLPTLHLLGFHCYLTLKNLTTNEVMNAHRYEYMRSAAGAYRNPFDRGMLRNVMDRCLPTSLISGSRPRRRYPRKADGKSSDDERQRLHKTTPEEDEGDLVAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM49</accession>
    <name>A0A8K1FM49_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADP-ribosylglycohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM49"/>
    <dbReference type="OrthoDB" id="547734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="entry name" value="ADP-ribosylation/Crystallin J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="ADP-ribosylglycohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="10435" checksum="3FA0DA7D1E792E65" modified="2022-08-03" version="1">MAAHKPRYASSFSGSGVTKSCGLPGVLKGSLFVLLTSNGYVDAVRANMVAGGDNCSRSILIGACAAAAAVTEGAMDPVPAEWKHKTKSYTQVQAFAERLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMD2</accession>
    <name>A0A8K1FMD2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMD2"/>
    <dbReference type="OrthoDB" id="46760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24118">
        <property type="entry name" value="POTE ANKYRIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24118:SF99">
        <property type="entry name" value="POTE ANKYRIN DOMAIN FAMILY MEMBER 3C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="15643" checksum="49AC30EDD326509E" modified="2022-08-03" version="1">MLLTHGLDPDRVDKNGATALHFASAGGHVGIISVLLDHGANVNLVNKKGVTALHCVSSFACEEIAEILLPRGLDISIADENGNTVLHVAAKKSTIKMAKMLLSYGADPYAMNVEGDLPLPCAARACYSLMVETLVDWGYDVNVRNAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMN8</accession>
    <name>A0A8K1FMN8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMN8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="90" mass="9743" checksum="69811BA83CDDC887" modified="2022-08-03" version="1">MIRGTRRAFQSARQIVRASKSKNGRRQVHMLLGEESVIGGRQRHAFGRSTTSDTIAKALATAVAGLPSRQVLDALNLLVADLTAEDDDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMQ1</accession>
    <name>A0A8K1FMQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001771</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMQ1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452427" description="subtilisin" evidence="10">
        <location>
            <begin position="23"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="174"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="612" mass="64725" checksum="19D1DEC151F00793" modified="2022-08-03" version="1">MVSTKFAALVLATALVASVISAAHVDPAVHRALRKQGTVNLVVTMKKGTKAAINAAKEASFSSREAQIESLVNRLQQNAEKSQVEVGKLFAKEAGGKYVRAESLWISNQVYIEGATVGFVESLATLPTIGEIREEEVYQLDEVTAVPANSTGSGNQWGIEMIQAPAVWATGNTGQGVVVGSIDTGVRGTHEILKGSFRGDYGWYDPEAGKPEPYDNAGHGSHTMGTIVGSNGFGVAPGATWMACKGCRTSSCRQVELLMCMQFMTCPTDPNGENQDCSKAPHVINNSWGAGARGSDNYKAAVDAWHAAGIIPIFSNGNGGRSGCDTASAPGEYDNVISVGATNSTDGLAEFSSKGVSSSGRMKPEISAPGKDVRSAWLGSDDGYYTDSGTSMAAPHVTGSVALLLSARPGLKFDEVRDILSNNVDTQSLMPTGYSCGNTVDGVFPNNMYGYGRLNAFKAVSGDAVGLPERPSPVPTTLAPAPTTPAPTTPAPSNVAPESCSTLGMTPCYYSEHCEWNYPNNKCQDKASTPAPSPSQPACSTLGMTPCYYSDYCAWDYPNKQCLDKPSPPPVTETPAEDTPKPVEPCSSKGMTSCYYSEYCNWDYPNRKCLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMV0</accession>
    <name>A0A8K1FMV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAC-A/B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW64003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMV0"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="2">
        <location>
            <begin position="41"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="19387" checksum="8879A237C1617DDA" modified="2022-08-03" version="1">MSQEEVNAKKHEEEVAEDSDDEIPALEEAQDGNDAEAGKHNRSEKKSRKAMQKLGLKPVSGIIRVTIKKSKNILFVISKPDVFKSTAAETYVIFGEAKIEDLNAQAQSLAAQQFKAPEPAQEAAADAAEEDDEDVDETGIDAKDIQLVMSQAGVSKSKAVAALRSNDNDIVNAIMELTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNE3</accession>
    <name>A0A8K1FNE3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNE3"/>
    <dbReference type="OrthoDB" id="163959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482139" evidence="2">
        <location>
            <begin position="18"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="319" mass="32947" checksum="B0B7AE73B519F09A" modified="2022-08-03" version="1">MLRSFVSALLLAAVVRAQSERCPGQYEMSVEGVEGIFCVADQRICIAQVYNGACPEQQEGLPYGSYCGVVATGVYGCKVLDANSIQTLTPAPEPSSETPEPLSEIPEPETPEPSSETPEPETPEPTSETPEPETPELSSETPEPSSETPETPEPASEAPTPQPIVFTPSIAPAPTTGPSSCENNWSPMSVQGVAGVFCTPEPVCVSDRENGGCPGAQDGLEYGASCGIVRTGVYGCIPNNSSGLPVDIAYPLPTSCAGNEAGDTPVSVEGVGTFCVNYPVCAGEISGECPGIQEGLERASVCAKVRTGVYGCVVPAIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPU7</accession>
    <name>A0A8K1FPU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methenyltetrahydrofolate cyclohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPU7"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="8">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="9">
        <location>
            <begin position="141"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW68729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32765" checksum="98E41AE664665CDC" modified="2022-08-03" version="1">MARVIDGKAIAKALRVAIRSDVQTLSARHGRPPALGLIMVGDRKDSALYVKRKRIACEKTGIRSEDFLFPEQATQAAVMAQIDALNRDPAIDGILVQLPLPSHLDSQEVIDHIHPTKDVDGLHPFNVGELAMRHRYPYLVPCTAQGIIELLDAENVELQGKTAVVLGRSNLVGTPITLLLQKRNATVIQCHSKSQELRRYVEQADVVVAACGQPYLVRGEWLKPGAVVIDVGINFVQDSDTQTYHGTETKDGYKIVGDVCYDEACDVAGAVTPVPGGVGPMTIAMLLHNVVAAYKRHVGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSH5</accession>
    <name>A0A8K1FSH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124677at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1590"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1647"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1590"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1647"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1666"/>
            <end position="1678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2488" mass="277976" checksum="E44045921F01BA3E" modified="2022-08-03" version="1">MDEAYEQALACEGTAGSVFTEDQWIAWEEQLALAPDVATKKQLVHGDKGRLLPDFPYRAAMCTLFEVQELLDEKTAAAAQKADDVLKTKHGELAKYVSDLYTRNLWRKAQRINYRRTMLELEAAIQLNKSKEEIQSLSSGMAVLMGVSLIDTPPADCDVQMEKEAPLPTHLDEKDLSTEAKLVNAIRGLKVIVSDYTAQTKVQELFSGMDLHARERFFAMVYRTSTQPSDLQLSAERHWMVLKLFLEDFAFECTDVDGYVDLIIEDLTRDSTTRREFGTREAHNRLSFPQLTVILQKQPQLVQESTAFAIRCVQLLQAVTKAEQRESLDNSDLGRDKIQYAGIERSLSFLTQMGPAVNSVRAALLHEQLQILRYQGASKQLWEKLVQYIQLPRFGADYVNIAHVNRSSGNELVVFHTSDPSLFGMRHGLNVQPTSWTFIESSSMSLGLNQISPSTDLQLIKDILHVLWAAEALSDQDESLLAQYLSLDMLNKEKPEFMVKSGCGELSKWIDKLPDKGQELSRWSTSTEISFCESSPKYFGPEDDLDVFIRVRNVKKLTVQLYEIRTIDYYSRVRHEIRGNICLDGLLPNEEQHIDLSHLSPWQEKRVPVKISSRTAGRRGVFVVEVFENGTTCRAILRKGFLRHVELVTARGHEFTVFDERGNVLKDASLKVMNSKTGRSRAQSPRTYHPDEQGTIVVPFRQADEASGDKFGILLCQGNFGFFSSSFRYLEARYNLQADMHVDTEQLRPGDVAQLVTFPQLYIQGTSVPISSDILTDVKVSVKFASVNTETSGSVARQVDRQFSSLLEFTGAKFEFEIPLDAASCNVELSARVASDHVKPASTQDLPVVRCQNTFQVQRINQFEGTYTPHFLRRATKFAGSVATEWEFYIAVLGHNGEAIKGKGVAVTLKHLHFSREIKQTLQTDSQGEIKLGALTEIIRVTAAFSNDQEEEWIWDVPNHIVSLPRSVNCAIGERVEVPLPFAYSRDIKQWVASRQILVCEVITTDSNSVLEDITNSSRLAPRYNTRNESIGVAFEATKSGKFVLFVRPLDLKYTVTVVKLANRERSASRGLLVEKSKILFETSTLPVSILSQEIVSEGSKKLLRVHVANALPSKTVVWLICKRFLSLSDQHITVMARNSGSKDGSSGLTFGTKLFDNEYLKKRKISDEYAYILQRRAFLNENPGSLVLLGSSSMPKPTLLQNPRILDQSNMEELVMRQGEKVTGFGCVEREMLRSQADEDIDAKKERRRQQVRYASRRSSKKKRSGGNVCSSSSISFLATPSESVVTGTLDEGGVATFPLSDMPFFAAEDTFVFEAIVSATDMASGFMTSREVQLSMNGDELAAPNVPKRDIRLSHEEALLPGCKSMQIQRHECLFVGDTRALARTFSSKYALYETMGSAIELWKTLCQDPLLPDLAAKLKSWSTLSKQAKIGFYFINASDDLNFFLFWKDREFFEKCVKQLVQGKLVKSLVDYYVLEDRVAISKRYLAPGVFRKLSVVEKLLVADRVESTETRRRICQHVIDEVDSTLGVGGVGSQLSRVFDTILSQGAVKPEEAPDLYGEVTIDESASFPPPGGGGFGSTGGFSFGGAPRAMAMQQQPMAARASRLSTSQPESAAFSFGAAMAAPAPMMMYSIPANDFEVIPESSTSFDVESIDSSDGNNSVDQDDDEEEEEVDYSDQSTSTDRKRNAQPYVRPGKVRRVGEKRFFGVQKPDLDGRNMFWRDYAGYIMSASTQSADKGLPFLSSHFPEALRSLTEGIFATSVLGLDIDAPATGIVQVSGGLRVRLEAASNVILYHQGVGEATIDDTPNSTLIVKEKIVLKSELATASEVSKLGSAREFVVNRVYSCVVTVSNITPSRLTNVNLLLQIPHGAIPLTESGFYTKNEIVEVAAHDTNTYTFDFYFPTVGEFKHYPAQASWKDKVIAWATQENSVTSITVVLKPSAVDLTSWNDVATRGSLDDVVKFMHNEKDVRKLAMDALLWRCQEEAFYTGLIQYLSQRYVFVEDVWKYSLKHGDVEHMSEFYSGSETFCRTIGAGVETSLASSMSPYIQERFEHALAFDHIEFGPFINRRAHRVSGKIESHFGMTTDVATSSSSEPARILNKSAREYYRTLCHILADGVTLSGEQLLVMSYFMILFNRIADAMKVFKRVEEHFATNMIDSTENLIAFDYIDSYLDFFRPQGNVAETSFPRARQNVSKYSKLFHDRWRLRFKRIAEVLSEYDELHSASLANDAHARLSISESDGQNPVQSSSIPSNEVRLDATVEGDTIQLKSQNVGACEISFYRIDVELMFSSEPFDSFSDAAASKSSLTLIEPWKQVNVEITGASSVLSSGETHTTSFKVPSDLVASQMLIRIRELPESRLVTSVAAPLDLTRSYFNTQLQVVTMSQAGILQVLHKGVPVSSCYVKVFAKTGSTSPFYKDGYTDVIGKFDYAAINGDLLTRVEKFSILVSHPKLGTTVQQVHPPVLATTSSEFQAHDAQSALWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSZ6</accession>
    <name>A0A8K1FSZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSZ6"/>
    <dbReference type="OrthoDB" id="446422at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="616" mass="68340" checksum="65BB80517AB32F50" modified="2022-08-03" version="1">MVEKTGKAAGSVVLHRERVKTADGSATPLQTHNNDDADDLPVLSIRVKGIKRETSDSEQQQDDEEDDEDALDDEDDDDAKSYTSNQTEDDSEEDPEALDQDVDHDSNNNGASKPQVDPADAMKQSMGQSSKPVVVTTRSSHAKLPAALSLSGLDPSKGIQEPRHQRGSGSMNPASSTVSSKQDKKARHKFQFPDAELLKLMLEQEKQNAWSSALATSSTQCTVSSSSLRSSRRRFSSASIAPAMLPLRRKSFSLTKGPIKNLATEQELVSPAKTRLPTRRKSTSACLFAYPRSPKSPTSVLSSLPMPSLPPLTPPGISVDPFSSSSTSSTTPQAATAASQMVVRVRGRKSDGKPEVVISKRPARFFVWQWNDRQVRIPFMIQLGPHQHGIMLRQLRYVKSVMNDFPWAKTHLKELLAAYTKKEMSKEELYPQLNQLSNQVQEEIGSHIKKQKQLFIKKQRLTTQLSVATGVLNDLQVTKHGRHGKPHDTKLCYDPGQPTKLQWIRKNGDQSSEVMAVDEITIQCYSDETNEEDMSVGMKKAIKKFPNQIVPSHSLSLVTATRTLDLQLKSPMHREWLVTALHDVISFARQYKAAGARRQDGSSAPAQHNSHILRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTD9</accession>
    <name>A0A8K1FTD9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTD9"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerases I and III subunit RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="38581" checksum="B402D0966E2B8B41" modified="2022-08-03" version="1">MAKSDATKIIRVGLDAPHLPDVNSDASHDFVEQLKKQVKVKIQSLTDEEIVFDLVGVDASIANALRRILLAEVPTMAIEHVYIWNNSSIIQDEVLAHRLGLVPLNVDPREFQAFPDNEEAEATDENTIVFKLDVTCKFDPEHPNDVSKAINSTIYSRDLEWVPQGNQEERFGSIRPVHEDILIAKLRPGQSIALEAHCRKGVGKDHAKFSPVSTASYRLLPHIEFKQPVEGADAKKLVEEKCVMGVFDIEDIAGVATATVKDARACTMCRECIREPGWEEKIQLGRKNDHFIFSVESVGMIKPEELLPEALNVLVEKCNVALESFNEVADEDEEMAEEDDEEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1X2</accession>
    <name>A0A8K1C1X2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003141</name>
        <name evidence="3" type="ORF">Poli38472_014942</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000169">
        <property type="protein sequence ID" value="TMW54922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1X2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28986" checksum="3EB248C431852D94" modified="2022-08-03" version="1">MESPHVKCDYTQIEVKKVQAPAPSAPSAPEFEAFVYPTDSPRSSPEQSHNPPPPTLTPSSNSDKWVFALKVVGYQLVNAVLAFATVVIVATMLFLSIALLPVFGLGFFVYRGALPLVREVAMLDSKLANLITPDGDRVCFTSARPGAESILCVAPDLHLVSLQSTLVVAYYLTLKPLIAGASIALFALVILPFLPIMNDINGYYNSENRWVAGIEVGDFHFYADPVWYALGCVGISTLTKLLACLSRDLTRAVCCQPVRPMAVPVATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2I5</accession>
    <name>A0A8K1C2I5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2I5"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46571">
        <property type="entry name" value="SORTING NEXIN-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46571:SF1">
        <property type="entry name" value="SORTING NEXIN-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="59"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="9">
        <location>
            <begin position="292"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="448"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="513"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="694"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="163"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="696"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="789" mass="88960" checksum="261ACA31307E6721" modified="2022-08-03" version="1">MLLRGFLDREYPLSNVLSRHEYRLFRGAPKVKKKKVDMTEEADHAAQLWRELVESSLECELCNEPYDESDEHLPRLLSCGHTFCQSCLDDWSSVGASTALGHARAHEVAVMECPTCRRPTQYTAVEGARSLPKNFELLRVRQEFESQTQPQLAKLKQVWTTQVLEKERLAQEAEEHAMLAQRESVEAAQRAMFLAKQVEINEQEKRRAQEVAQEARRRALVASQQAEALQAETELLKQRLHQEALQLQRVRNDASSAAAEAAELHSRAELLEQQVEYVRAQLSLHSGRHDPSKLVVLVVEPTTVGSWLLPYTRYAVISIASDAQRSMDPYLAAKTWTLNRQVAEPSASVKVYRRYSDFVWLHHELRRKFPFELVPSVPGKQLFFNKDKDFVGERMRALQAFLRQVLRHPVLAVTEDVRAFLLSTTEELEQLRNTARLNDDEDSFLKEVEESEIVSTTTSQRSSVDTLTPVSSPPSSSATSAASKRSSWAWGAVSAFTSSAAKLVTTTVSNGISGVTGSTTSLREGETTEKAMSSSLTPPDNGEGLDPQRRQSIETRRKYIEVAQAHQAVATRGSQVSRAQRRASHHLHRLCELMHNMDTLDQDYSKKQRERLAMSMDRSTYTARQVEEDARSCLESRTFQARASEVFSALSLSTKNDAECMEFALLEVSRMQTSHLGAIEDAFTRLRSKEDALQRAATSSNGASGTASSSSSYASDDFGLTSPVLALKQDELQQRRHEIQQLVQRVDPNRAAFVLDTLQKNVVEMHKLAQTRRKLFQDSQKQLRKASVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2U5</accession>
    <name>A0A8K1C2U5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2U5"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="253" mass="28956" checksum="8CFF98FAD50DF97B" modified="2022-08-03" version="1">MRAIKSYKYVTLDATGTLMRPREPIGRIYLVYWQRLTGQKLATNSKNAMEEEISTRFLVAFHRRSLARPNFGRAEAPNLDHTAYTWWRELILDSLPSELVAPLDSDAKDTFTKELYAHYATGEAWHVFDDVRPTLNILRDKRVPMAVVSNFDERLPQILQDLELSSYFETITTSWDEGVMKPDAVIFDRTFRRLGIENDVLFTEVLHVGDHAKRDYRGALAIGAQARVIHRGSTPPPDGIPHEHVLSSLAEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Z7</accession>
    <name>A0A8K1C2Z7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Z7"/>
    <dbReference type="OrthoDB" id="76256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="92" mass="10229" checksum="13417AA44A751AD5" modified="2022-08-03" version="1">MASPHRVKIYFQDDALRARSQANAQQLLTSASGSDGDNSNSARLAMKALKYRKVFQRMSGVDVNSPGFDAFKFLGVDWCKTASLEAHCMRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5L7</accession>
    <name>A0A8K1C5L7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006863</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5L7"/>
    <dbReference type="OrthoDB" id="448087at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039902">
        <property type="entry name" value="CCDC148/CCDC112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21549:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21549">
        <property type="entry name" value="MUTATED IN BLADDER CANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="388"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="533"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="671" mass="77516" checksum="BDCD4F7D20BA8169" modified="2022-08-03" version="1">MNRVKGTAAVIAPPPPRKVFRATTGLSLDQQLHVAASLQASSHDVLQKIQQMKKTSKKQKKTTKENTLKYEWLQENHRLKRMEETCSKELESLLLRMYNDACTDRFSASNASSKSTSSIKKSPRPEMDSPSAKTLTPESSVANQYASELEELITLEQTQRVALLKQVSSERDQRLAMKQLLASLQNNNQTNFESPAASKMRQQVQDLIFDAVIGHQMVEATLEDEYKQCEDDYQRTYRSIVSGLRQERVKDLPNNQLGSQQVDAFIASLVGIDGCLDDMLLLDIRDEFQRLQNECSDDLAAYERDFRLLAAQDDAAVSMEAASSETGGWLPAEDERFLTVLKSYDRSRPGPSKKPELLYDQISAVLPHLDRQQIKRHVRFHRHLRFYQEKCRDRAKDHERKMSELKTQAQERITQAVEQEREKQKKMEELQRLRDQCQHLHGKVSEWKQTKEAEARIQAQQQELERLFVEQQKTEEENMWRRKHELQKHLLEDYRKSRLLDVLAGERETQEAQEREEAERAAQSAVNAERVQFRQAEYERKLEEDRLEQLRREAEEVERLAKIETIKQQVPYAEKLAAIVADPERTRQETAAFRANFEAAEDGLPVHEKGLFPSHGYDSDTLFKNARFKLGLALRDAGLHSTEYARQALANIKVSNVGAYRHAVAPSTQLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5M2</accession>
    <name>A0A8K1C5M2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5M2"/>
    <dbReference type="OrthoDB" id="116699at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="823" mass="92449" checksum="2B59CB34F88153C9" modified="2022-08-03" version="1">MEEESIARTVRIACGVLGYADTFHVDTPLNVSVGDLKKKLVQEWTGDPSYALGPKDVTLFVTRKGDGTWLKEDDDEFTSILLGTVQKPFPIMLGTSPLFKDTNLGSSFKYAYGDHHVLARIDLRHEQSHETSQAPEFEHMMNVEPSYEEITQAYRETAERLKNHDKVKQVIAAINQITKYRVEELTSRIVQEDMPFIVLESSSGTGKTQMAFNLMAHEDLEVYYLVHDQQPIRQKVYSAVATRSNTFKKCVKKDMPYIDDGAIVAISSMGSLYTFAFIWALLTGASSVSGGKTRSEVEEALRSKTESGKIVVVFLDKFPALGNQEDERKVFMLRFIQNVFRAFGIVVIMSATNGTARNLITTGSHSRSDSKALWCIMFPSLPSFQDPSVELIPSELQRLVRHSRPLFAHLALKQLGSDQLPGEKEELIEYLNILMGSLADQFGGWKEHWPDWFRTGQVCLFLCGCYVVDRKSGLLHGHFARLAEDEPFELMVGKKDLTKNDETGQWECRTMFPPVYEDALLYLTLTGGKYYNPLVDATGDPIPFHTALSEVPASFVRFDNDKQLSEDGMRLESIVGASLVVASHQDGFGGSAFPSFFLRFLFELGILESRDATVSLPKLPLMYESPTNRCVPFLAPPNQVWPNTSANELLQLGTLRRVRNEERIDFCFMGGEVTVECKDYSDPPNVKVIKDILDRVPEASRIHLVVTNTLQASYFNTESFDTFMKADPKLPAEGSKSLKPPRAGSLRHARIYKMSANDRSFSEITMMENKCHGENCRPDCDQLDKVILFLLRGSRGNGQKEDGKAPPKKRKTAQSEDSVMASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5N1</accession>
    <name>A0A8K1C5N1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_002961</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5N1"/>
    <dbReference type="OrthoDB" id="1689029at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000034">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF0">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="14">
        <location>
            <begin position="13"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="13">
        <location>
            <begin position="284"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49939" checksum="128DCF6D27BFE9C7" modified="2022-08-03" version="1">MSSSSSAAWEDLAYLPGFGGHFCSETLPNALPKAQNNPQKCAYGLYAEQLSGTAFTLPRHKNQRSWLYRILPPVVHEKYKPVEQPFVKGDFANETLTPQQMRWNPMPLPQESEKIDFIQGLRTIGGAGEATMKAGIAIHMYAANVSMGNKCFYNSDGDFLIVPQQGALKITTEFGKMLVSPHEICVIQRGIRFTVDLDGPSRGYICEVYNRHFVLPDLGPIGANGLANPRDFEHPVAYYEDRECEYQVVNKFGGQLFTACMTFSPFNVVAWHGNYVPYKYNLDNFCTMNSVSFDHPDPSIYCVLTCQTDEPGNAVCDFVIFPPRWMVMEHTFRPPYFHRNCMSEYMGMVYGEYDAKKGGKDGFQPGGASLHSCDTPHGPDAETFLKASNAELAPQKFDGGLAFMFESTYLIKLTKYALECEHNDPNYYQCWQKMPKLFDPTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5T2</accession>
    <name>A0A8K1C5T2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_002977</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5T2"/>
    <dbReference type="OrthoDB" id="10251371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="224"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW57052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="318" mass="37410" checksum="5715829967C7DD2B" modified="2022-08-03" version="1">MAHRDLTDKFYVRRTNLKKRNLRFRLRQLQENTPYLPLFQSKGQFKIKGMDKALLQESRELAGMEAGEIPRPEWIRFADEANEAVRLLHVKLEYLQLVHTKRLMIRFDDSEEAYEREIDQLNDEITALFHLADRLLKKITGPFVGGEPSASSADRRVRLSTQRAIATRLQDISLQFRQRQREYLHRLQLQKHGSDAFNFDPDAEPMDQERYESAQMALVTDMQTFDIKTRDTEIQRIARTVSSLAVIFKQVADMVITQGTLVDRIDYNMEQVATRMQSSLKEMRRAEQYQRNTRPQRCIFLLLTGIFLCFVVLLLKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5V3</accession>
    <name>A0A8K1C5V3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L13a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5V3"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000009">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23073" checksum="E7451716F5331817" modified="2022-08-03" version="1">MVFEKPVVVDCRGHLLGRLASLIAKELLQGQQVVAVRCEQLEVSGSHVRNKVKFLQFLNKRTATNPKKGPVHYRAPSRMLWRTIRGMLPHKTARGAAALQRLKVFDGIPSPYDKQKRMVVPDALRVIRLKASRRYTVLGRLASEVGWKHGELVARLENKRKIKSEAYYKKTLAQKKRLAEATTKVFNENSELKPTLAKFGHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5W3</accession>
    <name>A0A8K1C5W3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5W3"/>
    <dbReference type="OrthoDB" id="74640at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="96" mass="10589" checksum="7C3BE6875C4199B1" modified="2022-08-03" version="1">MTMSTHGAEASARTGGTALGGAGSASHGDQRWKTSAAKPQMNSSYRNIVMLEKRKRSNEMAAKEMSHSLMKETLTGLRQKAADLQNDKWMYEDVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y9</accession>
    <name>A0A8K1C5Y9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA pseudouridine 55 synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase Pus10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y9"/>
    <dbReference type="OrthoDB" id="271937at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2510:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3190:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039894">
        <property type="entry name" value="Pus10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048741">
        <property type="entry name" value="Pus10-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048742">
        <property type="entry name" value="Pus10_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01213">
        <property type="entry name" value="pseudo_Pus10arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21238">
        <property type="entry name" value="Pus10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21237">
        <property type="entry name" value="Pus10_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pus10 N-terminal eukaryotes" evidence="8">
        <location>
            <begin position="98"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Pus10-like C-terminal" evidence="9">
        <location>
            <begin position="277"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00075270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00079393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="512" mass="56978" checksum="C82BCC3E9E60D958" modified="2022-08-03" version="1">MLDPDLSLIVLSESNSSGAPREDGMDMEKVLKTAPWLQPEGFLKAIEAGLCVRCVLRFGGVQQHDVYAYAETTLREALYAFLQDAGLQVNETMEKTVCTCCLDILSAQFHDAMIEEVRRVTDGLNYDVDTFTLNIKLPSAVLLREYSLREHFGQIIPGYRSNILSVDLKDVLKSLVTDRVAKVIDVATCAAKSEFAVLLEIKHDESAEEAQQIPAIKEQLDTRKKRHRGPPPVLDGFGAVTRALAALTTMPSTVKCPPPALQSQPTCGVVLERDPVYIQGRYLKYKRGLSQTPWVLDGVRMGDSSVEECIGEVGLPFFKGSGYKFHTAGREDVDVRMLGNGRPFILEILDAKKSKLTPAEYEQLQAAVNTTHQGAVEIREVKASTKEYFGKLQAGADSKRKTYCCVVWSEKELTPDLVAKLDAIHDLTIQQQTPIRVLHRRTLMTRPKVIHATKCEVLNKHYMLLRLTTSAGTYVKEFVHGDRGRTVPNVSTILECEADILQLDVESLIDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6J0</accession>
    <name>A0A8K1C6J0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6J0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="53988" checksum="3BEB7F0B22590636" modified="2022-08-03" version="1">MQAPSQGNRYLYRIVQSRPSPVVEMSKGLKHAIFRQETARKLTRLKRKYSHLAAILYVATFPISIAVLFCGASEGQILAMISSSLQIPMMVFVVLSLRIDMLRLLLSTYDFWFFSIMNFMTLTLLALSYRDSRVVLAFFTWLNMQYNVSIDATLSNSRGSILASFICVSYRRAVKLEKIQDATSPRKIVSVRVSSNAAALLEHVASDIVYNAEQTLFGYWLSLDAWPAWKQRLFQSSGLLGLDLNGILFLYWSYVAQEKLSPTLEMLTILVGVVASFLTLCFCGICFAYQNPGLLRHVCFSFDYAFLMFQFTVMHLSACDIFLWDQRSFIILSSLIWRHWVLSVDAITPPARHKLGLNLRHTAVLVFTLVVSSSISLYEFANGTKWRLRNRKLMTIKAYGHSVDVMILPVFFTRVLMVLLWDVRLVWRVVKEREENALVVTQGVMAFQQSKISSDLALLPAPHATQICPSRVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Y9</accession>
    <name>A0A8K1C6Y9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6Y9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="356" mass="39566" checksum="E2F720008C33A771" modified="2022-08-03" version="1">MESSNQVGRLSTRSMLYQEVVTKPTVRSLRLQHRIGGDTATELFSALRASNCLKSLHVEGILQDKSDADRKLLRQWLTWAIFSRQAAHKIQFVSLSDWWLTFDDVKAVEELLNASDPMLLLNGTPSDNNMTEIPASESKGSHVKGLTLRFGDVETTKADSAATRLLVVLKHLPLVKLSVSVSESPGLSGRALRAAWTGYPALEELTMSCVKLTSNDDDVFALTDCPHGLRTLQLDRLTLATHTNLMRFFKALGDFDANPKAAALEELVLDVSVNGDRYAHSLLNDVKSMLEKNDRLRCCVLRMLPMSSTEATREVVMQRFDGQVIPMLPAARPSRKAVKKRHLFGNGFRCTSLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C762</accession>
    <name>A0A8K1C762_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C762"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="489"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="491"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="540"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="594"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="721"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="773"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="825"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="353"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="919"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1087"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1142"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1092"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1161" mass="128690" checksum="23D1ACD5F0EDC929" modified="2022-08-03" version="1">MRRAHTPDMRVTGLSRALHALTMTCEQHQARGASMDVTTQGNPGAGVYFDWEEPTKTTKKTMEEEEEEDGRYEVVYPYDMAEAGEATVETETESLRRSTRELMAKLNVPVKTVVYEEERPTRLDHKTLSARGENQENPRLSHSYMTISRQTASASRLMELPLHRRGCDPPTRRLQSTSAHRRHRAAGGATSRSYDVHVPSTPSVVPFWSADPAPVPPQSTYRENYQWPAREELTRVIEKVDGYTAGGEARYQPIRAFTASEAFVVAKEAARDFLRKDVEASVVLSPSVVPEPPSVNQVQEVERHVETVQEGETKKIRDEKRRNAVDSSVMAIVPEAPTREDFTQTNQIEPLKEKAPLVYKRRRPSPPKPPSTPIEQPQELSVKSTNSFSRGSEIRYQLKLLRPPTKGKAVTIHVCVIMNKCGLTADPTELVISASDWRLPREVRVISDLNAEVRTVQIHHKIHENYDDVYTSITIIPSVFVSVLQKEATFLFTFGCGLHGRLGTPDEQNANEPTPFSSKWLHPVQIACGKAHSAIIDVYSNIYCFGNNANGQLGQGDSNLEPSKRPLRVLSVGTGSVLQVACGSNHTMCMTTEGKIFVWGDNTYGQLGLGTKFAKPRGIPTRVEKVVNVRNLYCGGNQSFIVTLDNNVLAAGSNIAGQLGLGDRIDRATFERSAFFRKLAAASSNTGTTLLTREQLLQVSAPVADLELACGPYHTLAVCSKRLYSWGNGDDGRLGHGSLESFLEPTLVSAFDLIPIRSIACGGSHSGALAANGDVYTWGNGHYGQIGIGSTKNRRVPTKVRLLQNKRVIQLSFGEWHSMALCEDGNLYAWGFGEEGQLGLPDDAKQKLTRVVSFPTIVSALSGTGATTVRCGSAHTFVISVLESRRPQLAKTHRRASRLEIVQETGRLETLERQKSRVLHGEKIDETDSLEDDTVKSKTETSVSSKSNPKLDRVQLQAWKSERSIESLNDDGEQDRVDWSWKDRPMTSRTAVRNALRQEAKVMTEMKEILTPRSPPPAHRAERARAAKAFISPRLKRLHEQVVRSSEAGVASARRKEVINNPAASQGIEEAVRAATAPLLYPQRMDVSVHGRPSRPSRHGTSRTPPPRHVMSYEMEMSPISTPSDDSERVDDEEVAWVGSGHDTTALEEQIREQTLHNATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7A2</accession>
    <name>A0A8K1C7A2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7A2"/>
    <dbReference type="OrthoDB" id="128611at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="286" mass="31819" checksum="EAFEF365B75D1A4E" modified="2022-08-03" version="1">MHARQASYDPYVAILSELKQLREAMQCMRTAVDAIVPAVVDAVVSAVENQGQTILMSRSELQHSIQDAIEGLKARPTVSVDCDIDAVFTPIGSTCGLPMNGASMGMSSASSSMHVIQEESTSRTMPPNAVPMASMASMSHTSDVTSSGQRYLWGNAWHDVPEDFEIPRSSLPEIWRLWCRGDPVKGYKPLRQLETSDVPTKNTRKRLSDLRFLMRHIESLLIKLNVWRESPSEEEANQMLRAAFDKLPLADVAANGRKRQPDDIKWHSAVSIMRNAVSNKKARITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7U3</accession>
    <name>A0A8K1C7U3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7U3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="578"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="629"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="704"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="734"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="763"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1142" mass="129204" checksum="2A89B5316CEEA6D8" modified="2022-08-03" version="1">MTTRNRFEMQQIVMSRVSIRAVTGSAFTSLTSITQSAFTFVLPFIKLGLRNHFSRVLRGVDDVKSVFVVLDVDLFSALNVTSCLQSSHLWINTLLIMVIDVLQLVISLNDVRNVMKEIRSMVQLDKYKGSLLDLSDQRVHLVQKIMKLLYIVEFVLLIELAEVMIPIIYSIYLMAMTYLPNKSYYHQLASLDEYHLNHSITKVMLNATLEFLSFLAMGWLLQRELRISTMHLLAFALDTERVLIQASLLSWILYVNHQSLAHNERGRNGNAIYWIRMHLFIFIMVSGRIKQFHCCVPRLDLRAHQVVAVAFATATSATLFVYVLSSAVGFPVPFAVICASLMGLPTAIFSMFMVLRKMIHTDPELKSDLDSHFLVFIGETMMTYIYPMYLSAFKSLSPSSQSAFTLLLPLIKVTLRNHFGRVLRGVDDVKPVFVVFNVDLFSALYVTSCLQSSQSSFNIVLISTVDIIQLTVSVADVRSVLKEIHAIIRRDQYEGSILSLCSAVASNPKVRKELDRQCLSAKIANASRYNVSTAPTRQIVPVSCAGEASSLQKAKKTSLPAGIRSAQRVRLVQKITKVLYIAEFVLLIEFAEVMIPIIYSMYLVAMTYLPNKAYYRQLASLDEYHLNHSIANVMLNATLELLSFLLICWLLQRQLRISTMHLLAFALDTERVLIQASLLSWILYVNQQSLTHNAATTQGKDSNAIYWIRMHLFIFIMICGRIKQFHCCVPRLDLRVYQVILVAFATATSATLFVYVLSSAVGFPVPFAVICASLMGLPTAIVSMFLVLRKTLRVDPKLKSDLDSHFLVFIGETMMTYIYPMYLSAFKSLTSIAQSAFTFVLPFIKLGLRNHFSRVLQGVDDVKPVFVVFNVDLFSALYVTNCLQSSQSWTNTLLIMVVDLVQIVISLKDVQRLHKEIKTLARVDRFDGSLLDLCTMVAALPDVRNEVEQRCSSIKVSPPGKYSVSSKSSRQIAAVSQVATSPSVATVQEATLAIGLQPAQRAQLVQKITKLLYTVEFVLLIEFAEVMIPIIYSMYLVVMTYLPNKSYYSQLADLDAYHLRESIAHVMLNASLEFLSFLLICWLLQRELRLPVLHLLAFALEEQRVLIQASLLSWSLYVNQQSLTHNGVDFSFRFEWLHAKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C893</accession>
    <name>A0A8K1C893_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C893"/>
    <dbReference type="OrthoDB" id="153756at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17260" checksum="51491C3D44B6EF7C" modified="2022-08-03" version="1">MTKLKDVYGTYKKEMSAKFDNEIVAVVARGKPGYANLNHLNVGSPGSDISDMDDTTDLEELLAHGTSKGPQTHPCIICCAIFSFSGFILLLIVGSIVSSNSLYIHVTPPKGKKKSSLATSIFLAAFLYLCVFGTSVMYFLRARRAQKVYQLSMDVHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8S1</accession>
    <name>A0A8K1C8S1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="4">3.1.3.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_010062</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.99" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8S1"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="391"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="48236" checksum="0599CD572DF8FB77" modified="2022-08-03" version="1">MLKEQDPLIEMILEGIMSPGHDTADMDVTITDIFQGVQDMMLEHHENPEGQTRLKKYVPSMKKVFLPLDLVSALKEYDAKKHLLARKRVPPTFKEVRHVLNLSVVNAIAGKLKLVTFDADDTIYEDGGSISATSRMVTIIVELLRRGLVVSLVTAAGYPGNPGRYEERLRGILDALESCTKEERARFLVMGGECNYLLETYTKREDGKVYLREIDGALWKDGRGMRWKEEEVQALLDLAEKTLEETTAVLHMHSAKILRKERAVGIYNTSHKRFAYENLEELCLTLQYVLKDLPVPCCAFNGGNDVWVDIGNKALGIQALQNYVFRFLPKDLQGDELTKIQGMECLHVGDRFTRTGNDTRSRDAATTVWVSDPRETRYIMKKLLNAIDAARGEEARRPSIPATPAQAQREARVEAAIQAATEDTLAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8X0</accession>
    <name>A0A8K1C8X0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="9">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_010291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8X0"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000020">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="107" mass="12314" checksum="27093AF1FF69E768" modified="2022-08-03" version="1">MASVEYKRVQEDEEEFQKGPLSVLMHSVKNNSQVLINVRNNHKLLARVKAFDRHCNMVLENVKEMWTEIPKSGKGKKGAKPVNKDRFVSKMFLRGDSVILVLRNPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8Z8</accession>
    <name>A0A8K1C8Z8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8Z8"/>
    <dbReference type="OrthoDB" id="112281at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="465" mass="51355" checksum="80BE09FE0259CC86" modified="2022-08-03" version="1">MSSKRVSFHEHEDEDEEEMSVHTEEYSNGRRGFNDRAQGRPSIPPPVIPFVDNSAVQSPVRKKITALQDRRVNTVLLEALQLIEFSKDEVQTIEKSVKKLRDAIFGFSILVDKQVNIIGVETLEERGRIKVDIQDLAENLKISYEVFASTCNRMKQTLTTGKQHVQVHKKRVAARTPAEEASPSRPTTQSSQGPVSPASVSGNALLLEPGPNRSSLLSVLHPASNIDDDSFDPGPYMTPELFDSVLESVGLSEKEFLETKDLIRFAQEMLTSSIARSRALSFMGKAFHRRLIPGYAKDLVGLICDELQLTAMAPSLSPYSSSAPTISLPQNTFYDYACERLDNLLDAVYIHDANDFAGEPSPNVKAGATPSPNPFNDHITRNGGVLHGGKVVQHLLVNRPDPELLEMAEQTLAMAKLLHDLATAENEAKHGDRLSIRPSTSRAQEFSKTYLATSKELLLKESGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C947</accession>
    <name>A0A8K1C947_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127766at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="344"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="416"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="449"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="531"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="982"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1248"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1248"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1267"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1285" mass="143329" checksum="1361455566AD3994" modified="2022-08-03" version="1">MTPDEALFNAAQVGDINFVIYLVQSRRIVNLNYHNSDGWTPLMIATRHNHKDIVAFLIHSGADVEARGIDSPTALCVAAGNGHLKIVQLLVDSGAAIDRAMAEGLTPLLSASAQGHADVVLSLVERGAALDHQSGTLETALHLAVRAKQIDVIKTLVQGGASVRVRDNNLSTPVMVACKEANVAALTAIFEALKAEGEQDTITDVLEVRTFDDRTPLIWAAGEGLLAVVRVLLNYGALLEGKDDTHSTALTNAVKKKQVKIAKYLVEQRANINHADLQGDTPLIVAASTGSMAAMKLLLKAGAKLQAKNQGGFTPLHAAAVAGHCEIVKLLVKRGAALEARTNRGYTPLLHAAEQGHTRVVQCLFELGASIDVRTHDGKTPLFASCHLDHDETSRVVLDLVTENGLLASLNAQDLKGWTALHCTAANGDVSTTRLLVERGAGVNIINGNGLTPLHMAFLNYHDRTTQILMERGGYPLSDDDSIWPISAIEELLGRPIVPGRDPRPAKRRMWFVTPSSVRFVYGQPTHLLDIVMCSGIWFGAPATILRPLPPLMSTPPHEMRHWWQDFRKRFFLQVARWYPLNHPHLLKLYGACHLPDHMLLVAERVPKATLREYIRDHPCAKWTIMHQVALAVQYLHERNRAHKRLRGDTIHVTEDGVVKVSGMNDLLSFHDNDGTEDIRWQSPQVLGGGGFEYPDDIYSLGMCIIEATTGEPPYSGYDPALHKYDLRKWISHGMPPDRSGFSDGEWDLVTRMIAFARFHRPSISDVVRDLGDLARVSQATDRARDVDVDVKLGELNSLLSVEMKLDYQALERLNHLRSIHLSAPSSPGRAEESFRRILTLFTKYLAQYQTDVDVEVIRFIERRHEDDNFSLHNDIDRLARELGVDDLIAEPIHEWRETWHDHRIARMNRFEKSLTETELAKLAASTDRIKVLTCLYFELRNHSSSYASVRFEVIDTACQYIKHLPDIRVADWFLPHYEIDFDQTHSFASGGFGSVHRGTWMSTRVVVKKAKENKTTKTVDPVLFEREVEIWYQLDHPHVVQLFGACHLPGEQFLVCEDAENGPLDEYLRRDTVCRRRVVWQHLYEAAVALQYLHYKGILHRDLKCNNILIGSDGNTKLADFGLSSVVGNERDSKSHAKGAPRWKAPEVLRGEAASEASDVYGLAMCIVEAVTGKVPWGCLGGNQNELYDDPEVREFVKDGHRVPRPTGFDDAQWELIEQMTEVKASKRLQLDQVADAMRRFALEEAAGKYERTEPEAEHDVAEPESSSSCLSSRANSDSGSLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9B8</accession>
    <name>A0A8K1C9B8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9B8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035440937" evidence="3">
        <location>
            <begin position="27"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="174" mass="18338" checksum="0D8B4D99E5C06B58" modified="2022-08-03" version="1">MSRSAGRLVLMLVLVAVFMLSVCVSASTEMRPSGARVTSLRRVEAVTVFSEDSITTTEEETTSSLVEEETESASSTTHEEETAASTTHETEETARPKKKKETTHVEEESSASTEADEDVSGGNASTKTEGEDAKETSHAKGPSTASFTGPLIAGVVAIVLIGAVVAFKNRPSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Y0</accession>
    <name>A0A8K1C9Y0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Y0"/>
    <dbReference type="OrthoDB" id="125661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035448498" evidence="2">
        <location>
            <begin position="20"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="29672" checksum="9CF52962DD0C5D51" modified="2022-08-03" version="1">MRAVAVVMTLLALTSSVSCTAIPTEVVEPLSIARAERTVDTTPAAATPAKSAATPAPAPSSASLREAHEITTTVPTTAAPPRSAMLQPATSSSATSSVASTSGSASGSKDATAKPTKKTSSVKTKGSDSQDGSTDGDDTGSGAELDPSLINACVCRELRMVSLMGAANYCLARGVSVGDKCGNTALAEKGACPRKGAQPCQDTGHVLTKNSQCVYDKRDDTYKCVASKEDLLLHKKGKRFKKKKNGTSSSLDPSAGGVDSTTSSGVVLVPRDDLVRVLTLVASLVLGVAALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA33</accession>
    <name>A0A8K1CA33_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA33"/>
    <dbReference type="OrthoDB" id="74529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1155" mass="131566" checksum="1B6BCB928CAC4B77" modified="2022-08-03" version="1">MRLREAIREWKLKRILSRQQRHEAKKQRAETLFSYIYPDDACWDKMKEAVNLGDLAFIQKHTLTCHHHRSGLLLPVAARKGRLDVVKHLYTISDSEMDPQVMENTLKVAARMNHLPILVWAHVNNLGGWSYKLMDVAAAFGRLKVVKWLHKYRTEGCTTDAMDNAAGKGHLKVVKWLHRHRTEGCTVAAMDHAAADGKLTTVQWLHKHRTEGCTTDAMDEAARHGEVFVIKWLHEHRHEGCTTSAMDSAASNGYLQIVKWLHENRTEGCTTAAMDQAAANGHEDILEWLQQTRTEGCTTAAMDNAAKRGNWQVVLWLDKHRNEGCTAKAMDKAAKRGDLPMVKWLHEHQNAGCTTEAMDQAAACGELDMVEWLHNNRTEGCTTQAMDMAAKRGYFETVQFLHENRTEGCTFGALNVAIAHQDVKLVKFLYENRPELSQWPQFKHVETLRVLLGSNDYRDAGMLECIIDSRRNRHAHAETTRVDEENQLKDHNGSSQVTRFRLTLVKFVLNHKLAESSFGISHLVSLYIVQDYQQRINPIEAADRGYIYWLALYGALGSGHLGWLACRGNFDGARRMHDCMNKTSCEWKCDDQFKLLTMERGDLAYIQWHIRNCSMKFDEVIYLAIWTGRNDVIRWIQTHYLRGNQDNAVSGEARWHEEPMQTELDFAAAANDLFTVEYLHNVKYEDGRCSTKAMDLAAANGHFEMVRWLHNHRREGCTTDAMDMAATNGHLDVLKWLHHHRREGYTMLAADGAAANGHLQVIQWLYAVDETSRGKLAPAKVLTAGQFESQETRRFRDSLPSILGNIRSQRHSPLDLAAYHGHFEVVKFLHEHQGGRLIATQAMDLAALSGHLRIVRYLHNNRSEGCSATAVYGALRHKYYKVALYLYQHRPECEQWPSDEDLPGFVETLLKSRIDPVIRQLLSFFYLHRNVQLSPRVMDQAALEGDINLVRVIHELGLGNCTTTALDFSAMKGDMEMIKFLHFNRSEGCTPNAMDGAAEAGRFDAVEFLHDHRTEGCTRNAIDLAARNGHEDIVKFLLLNRKDGHSPYATYWATVNNHVGVVRCMVDSKTLVDVDKCLQVARSHKNREMIEIFEELAVSRDVQRSSSSRSRARRIDTHCTKKIAAICPPQSIMLRAMRDFLSQSASDDLVSIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAA1</accession>
    <name>A0A8K1CAA1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAA1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF15">
        <property type="entry name" value="DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="62"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="304" mass="34371" checksum="B4B37F64D9A0C712" modified="2022-08-03" version="1">MDVSVLTPTQLESKGVTPYVYDDNLEYVDLMSMSRISAFEARSRHRMGRELAALKSSSPFKGPVFYGWLWKKGASFKTWKKRFFLLHGCTLTYYTHPCVISTEKLGTRYLEIPAKGGLRVAAAVLTDETTFGIRITSSSGRILYVQAGDHGPRLEWLHVLQDAPQKKYGTSAVRCTSVSDIMTSRSFDMASRESSPSDSIFSTMSSDGEENLISDIQGWLYIRTSKLTGFRKRFVTLLDGHLYITSSPRPQCPQDVAHEVILVAPWNGHEYGIHIHLDRHKEMFAHATSSEEMNLWIEAMTNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAL8</accession>
    <name>A0A8K1CAL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="167290at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1734"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2350" mass="263579" checksum="EEFD15795C7964BD" modified="2022-08-03" version="1">MSSPQKPSGSTSKPRGSEFPLLRARSPKKKNESTAKKTTRTNGQHIELPRVGSITYANSTIGTSTKTLAPVPDSGEELEILKCILVREGYLQRLTTASSAGKVSGSHLSATIDVLDLLRIATIEVVEAIVAWRVKKQRQLKATTNAPVDPATLVFQWNSLNYLLKIGSDLDFLEKHLGLVQWLGFTLTRNPFILPVNLDGRAKLDAAEHLASESPTHIIKSRANYDESQFVQVGGKRVIDRRPDTVEQHRAQMAGAALAERKRAKNPYETRVVNDEELVPMGSVKSGLGETTRPRSRGGASNGSSSSLVMPSQIGDLDMSRIRSCELVILQEERLHGRYTHDIQGHIVPEAEAQRRFNMVEMSDDAYSYQNTSAHGTVDDRASGEDERSAPQVESREAKLAPKAFAKKRAGMLGPISKPQHLKPTRKPPTERARGAHLEEALTIEKQTNLEFGVAIDGLREEIERKEMDLAYFESFSGVQFYGSELQDFQQKTHREVSQLRKDLTEKQYVYESRAASILRKEEIIHIFKENRKAAVEAEREQVIANQSKPIRGAHSSSLANQEEPKEGSTPSQPSENAALAISRATLQDFYGSAATSPLVHHMCATLIQKIARGKLARAAFESMKIEYYVGSKYIQAVVRGFLARRRVARLYWQLTASLVLQRFARGMLARLRVARKRLALRRERSALRIQRVLRGHFGRCRMLKIRKLFAARVELTQASSELGASDFKELAAACLSMVAIPSLSVSVKGHSHLQQPLTSLVLGLVRVLMVFTTDQDVDIDVCNVRWREAAHFLQCSVRLQRRMSKIAVASVGRYLRQSLLGSALLEMYNKDEAFSETTFSRLERGWRAATAIFRWITAFDSVSKLQSVLPPFDYVDGDDTGPFAFAQALTATERKQERVEDQENTVQDEAIVRRFVPKELTHVAKYPLHRPRPVLLVVAFDLPTQAKHRIMDKLMSLLPGLLVVLNRRSDVPAVDKSTQRRIPMAKQEQLETLGTDFTSVHEALAVGLSVVLECDVGLTDSQQRRFTGAFSALKAAIKPSPLCILLRGSLRNRREDIVAQVERPPGELNRNETEDSAADPTRGEGKLKALFEESAEWLARLAEPTVATQMARLSTEDSPPSPALVLAMEAIVILLTPTKRYDGPKRHVNGGGVSWKLSRRLLAKPRFLHQKLRDVAYDSITSDNLRALQQYLRHVEWPSAVLAHSVSYGGETVHSLASWVESVVKCAQTAEDLHGLAPMITRTTPVRGLFTNAIVYRNDFVDSYIQGEDSVLRELLDAILADVRVFRKCHILDGRRCVLNVYHDCQRIYFTAYDPETSWRWQSVIPEGDANTLLAPNSIERSDVSKTPPTTREEMYSRLVDLCLLQSINAPRKTSLDTTALRSDEKELIVRPTAVRLYRRAIRLNGRQATVTMAELSRGRIQVDVFVHGSAMEIRRIVSLEAILERLSNLASREHFILPERLPAIVLERLHLFSRYKSQAYHHVDDSSEAKLVVRSKETAPGRLLLRKAIQSPWLPSRRGASSTRWMLSVYEHVSTGRFRLEVYQPISCERFSFFITRREFQDLSLTDLCKRASGPRPSVLQKLLTRLHFVLDAEADDVEEIPQIHTCHVRHIHLRFPLVLPFIPTPHQVVELRQVLRCYVQVETRMRSTEGQASHVEPMGELVYRISMPETCEEQTIVLSDAEVDAYFAHSEALWRAAPLSTRKSMAYDLARHALHWDSSTKRVVAHLPSEMFEASPSTRQTGRTKQKPPPSRGVVSRKKSPFSLRGLQSSRSVPIPSTCVRLLDGDVSEEGIVFVYDREESIHKGSYRANGVLVMVEVFMKAIVVKTLEPRVPVDRVVESDSFEVRFDFYHPGSSQKRSMVVLGRRELREVVGPERAELIASSSVHELIEYIVEARTVITFEAKGPEPKEQATKTPKHSPEMQVAFIRDRLYAKQKATPINDVSAADQAKNATKLIDQRAGRGLKILSKSRVLDGVGRTIITVFDVSHTRSQSTKLPDGMVQLRVDAYVCTTSTRLSLSLEAVDLVQVVGEAKHLLSTSSFSPSDIERKQLAERVVEHIAIECKRDGSADRLFLLETTPPRTQSPAADLANGSATELLGKTVRHIGYIQVLISVFLDLGDTSLRIRLYDPQISARDELWVPKLALALMFGLEEDILTSQVILDFAQTSGGAKIVVAHVLSFVCFEPIPENDNIETAPLMRVRASLQVDEHTAATLRSELNAHRGLGFETTTISQESTTEISRWKGLMMVTTTTQGRECCAVHVEVQQTATPSWRGIYSVYLPRKMVVLTSAIPPRVLESIVVGLNFNSTPITQTIMQECRQKMVISRQIDGFESDDSLTQQFQIQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAY2</accession>
    <name>A0A8K1CAY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="166094at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="748"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="809"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="846"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1838" mass="203951" checksum="F07A1402D0D06256" modified="2022-08-03" version="1">MKVQGENEVLPRLHERKRAGTNEEDDVKFLGRMSWQKGLLDVHNDVDSKNANFSLGSGSRYGETNVSSSIPLSSPWLSSPWLSPSKSAQSLPQHSREAHSSSTAKLHRSVSVLTNNSHEALPGRSGMTFEESMAEVEQLLEQHVRSPHRQRNAKIKPLSTIQQSAERRDSTKSTFVFAPLRDPEILVATADVELDEEGGSAGVEQDESNTDQLNAEESSVDSPGNQKYFGATAKAAYYKTYKELHGKPHLFVETPKKAAQLKSLKTPKSIELRKSRMMNSIAAPASGSHQVGSPIRRPALQAPPRVASSSALAASVDAISTPPLHSPRVVFLSSCIAKSHPAMSLVLRRENCRVFDFSHQGLGDEFIIEFAAALPDLPLVEAIDVSDNRLSDDALNELINALDNKPNLIKLDISQNEIGRKSARSLRKYVSSSMCTLKTVTLNNADIDDQECTLFMIAFEQNKSVERLFMRSNTIGQTRKSMALGAAAAVASTLPSDVDLSGAPLPAGGDAIASMLNVNLNIRELDLSWNVLRYSSCAPIAHALQLNYNLHVLNLSYNGCADHGAIVLGNALRTNSALRSLNVSYNSVGMKGGLALASGLIVNKGLTELILDGNPIGLESGRELMHASCSRIHTQTVCRLSMFECNLHATGRAVRIDPAAAKNLGQVVSLNVYNPSDPVGKYHLDLSDPYEHMIAHELLRLATFKSEFRFAKLEYTTATTPKVTTRIELHRKAVAQAPPPPQEASIPDAPSPLALLFTKIDTDKSGFVDPSELKDALEAYGIHMDDGVLTRVLQEYDYDHSGALGMEEFEDFLLRCGFAMIDTNHSGALDEEEIANVLRLMGFKEVSQRELRTMINQYDLNNSGEIDEQEFIEFMKAEVLQRHQLVALRKEEQAATKPVLLSTPSGSLDDNYERVALRDVSGVIWKVPTSGFLFVDFVSEMKTDGDEAFDDPNDLSSPYLRRKPRASHLIADIAISKLLNNIQNISNNSDEQSEFFQAVLERSNLFFTAHQAEGVLRKQGALKSWPRKLYGLSRILPQMVNRYEAMTLVNRVLEPSRQWQQRQELRRTVGKLFSVLLGSVTNRYRIDLHVESDRVLLKKLAVISQEEKQFSKNRSGRRDTSQNGNWENFRNAKLDGVPYLLTTQFVLNNLLTTQGSTSAERKFVEFDYISTTRPPRGMKCLTTRRFDQLVEVWTSTEVQAIPTRTTSTNASETQANSAAKNDARLRWAILRNYVFEMFHPKVASTSTKPSLFNVKSTLGSLQQKLDFLEILVSERWFNGEQASILIEMLPNAVLVRAQAAALLFARLIDLENFITIYDSLSSEDQRECIRRLGWLNIFDPTQPDRQYPPLDLSVHDERELVMILSQLALQEGRQCWRKASYRASFDGEFAYKVDELEHHNAALVRGKGYEWVTSGNFGQKLERTGCLSRNQVPPLHLLTRLLRMATLESNGSIRVQFAGEIYRIRREDGASSRPTKAIVESDDVLIELSPTSLAPGQPLPDFVDQIPDLPMCPVLFESLADDSTVSLSEQLAVDENVTSATSCTCEATRNCLFIHGIGVHDDRGLVDAYPEYWGDIQRSMPCCSVVKFTHLNTVDSAWFSGLFAQRLCDALTATATNGTFVLTNDKKPKKNSQLTPLKNLIVVAHSTGNLHLASAFLHNECSLDSATSKWIAIQGPMRGTNTANRVVEECNKPASTWDKLVQTVVHDFELCPVKNSTKSLVLKNTPVSPGCLNTLYDKATRVYNERVNASLCGVSPFGLTSTSSPKFVALAAFSNHSTSENDGVVAFESCLSSARDYQTTYRSAFYKASINHDDGRLIHGDGVWGEGRKPIKWLQCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB33</accession>
    <name>A0A8K1CB33_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB33"/>
    <dbReference type="OrthoDB" id="122626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="416" mass="46758" checksum="6BD2F344E2F05572" modified="2022-08-03" version="1">MEWSALELDDDPALLDAALLMLDTLDGGEGVSSTTSLPDSVLEAGTTSGSSDGEELRSEHSEKTTPSASSTAIVTPPKINKSRNRRKEELALLQDTIKQLETTLSTLKRRRVEDERAVVPLRGRQALWKQLAGRQQQQRRAVEKENARLRDMLNTQLQVSKELMRLVQKVGRVNPNTRLPYTPRPSVHIAGLTDAQRLARVDELHRLTCHQVLAVPMDVSGAAVSNTKIYRESPQMTLVKFVTAWSVPFSTMSVLDTVWKLYADPSVNLTRHNLDNETAGGFRLHPGIQAPRIVPGEIAGRKASKRFLPTANGDGVILSSMSAQCIPEDASSEVPFSQVQFYEDSWTRVRTLDQVWTDEPLTQIQINRQMRFHVVLEDEDEQERVMEMLKKIALAYVEEEVLWKQQVIENVLFAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBT9</accession>
    <name>A0A8K1CBT9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000546</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CH_dom"/>
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        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
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        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
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        <property type="entry name" value="MYOSIN"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
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        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="610"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="220"/>
            <end position="385"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="399"/>
            <end position="477"/>
        </location>
    </feature>
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        <location>
            <begin position="1167"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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            <begin position="197"/>
            <end position="207"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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            <begin position="303"/>
            <end position="315"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
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            <begin position="324"/>
            <end position="335"/>
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            <end position="352"/>
        </location>
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            <begin position="406"/>
            <end position="422"/>
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        <location>
            <begin position="432"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="704"/>
            <end position="711"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
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    <sequence length="1496" mass="166399" checksum="97406EBE730F2347" modified="2022-08-03" version="1">MRRAEELQDWIAQTTEQPVEEEHLSVVLQDGQLLCLLANALDPLANVKVNKLTTVFHSKANIRAFLDWCKKQGLQDSELFEADDLLDGTDFNAVVATLSILYDKFGGAYVVSESIDFGQENPALSDSETSSGTATPEPTTPKKTTSNSKLASFMKASFFTLSSKPKRPATPEGTPPSTPPPMSPPQAPATPPRRNRNSSAVSTQSNNSRLNAFLNQVPASQEKPLEHVDRPAGPPKRAPSVRKENRPLNVPTPPATPPRKMSTPPSTPPRKASNGARTKFAAFMQANPPAAGDAPPLPRGGRTESNSSQSSNAPQVNLPVDNSFADRRAAFEPKKNAPPQAPPKPRSPPPPASKKSSVGDNKLKDFMNKQPPASTGAIKGRSDSSNSKLAAFIATTGVAPSISNTPAPRSAPSPLASFNPGGKTPPKPLPPANNAYANRNVPSSAPVASAPVAQASNSGERFPFTPRRVAERSTGRGNYVRKRQTYRQFRAKPKRFSLEDKRAKFMHEQLQLKEEQLRLQALGAASAKQNLIVPGVQCYVPDKEEVWMLSEIVEYNDRTKQVTIDAFLDSGETERRNVNLKDPEVIRALAGPSATEVESLPVAILHDTPGGVDDMRLLRYLNEPSILFNLKQRFEASKPYTYTNDIVIAVNPYKWIDGLYGDHLHDQYLRKPRDTIAPHVYSTSTAAYKHMTTNEQNQSILVSGESGAGKTETTKIVMNHLASVAGGRQDKTIAKVIDVNPLLESFGNAKTTRNDNSSRFGKFTQLQFNSRGKLIGAKCETYLLEKSRVVSITDGERNYHIFYQLLAGLNKREQSDLELDPSFKYQYTGLLNSMKIPGIDDAKWLDETRKSLSLIGLNESAQKTLFQILAGVLILGEVTFLESGESGSMISSTKELAQVARLFGCPTERIQAALCNRTVITRNDAVTVPLDPVEAVENRDALAKTIYSKMFDWMVTKINNAISSDESDIHAQIGVLDIFGFEDFVQNGFEQFCINYANEKLQQKFTNDVFKTVEDEYIREGLEWDHIQYQDNKDIVEIIDGKMGIIALMNDHLRQPRGTEEALVNKFKTNHHKKGTEVNPHIDFPKVKRTQFIINHYAGSVTYETVGFMEKHRDTLQKDLLDLIQASNIPLLVELFDDSESLTDSNGGGARSKAGPKSLGSQFKQSLSQLMENISCTNSHYVRCIKPNSNKSSTEFNKRMVVEQLRSAGVVEAIRITRSAYPSRLSPQELASRYCIMFPPSMHSPDVRRTCSIFMTAIGRKAPLEYQMGKTLIYFKNGVMEELEAMKSDFMYTEATCIQKIVLGFVYRRRLARKIRAAIVLQSYSRMVIERNEFLFQRQAIVKIQRRWRRYLSGPVAVVEDVHSEADDSIRDSVSSDGGQWVDEMDEFDDPIEVSSIRPPSRSVLERMRGYKDDSMTPGGRRSSLKRLGDLSSRAKSFMRNSGGSSLTGSSGMSMEDENSMLRIENRNLKYDLELMREQCIELQAIILEINKSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCH3</accession>
    <name>A0A8K1CCH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
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        <property type="match status" value="18"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF73">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
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        <property type="match status" value="9"/>
    </dbReference>
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        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="31"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="26"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035479515" description="Fibronectin type-III domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="6117"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="2140"/>
            <end position="2236"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="2355"/>
            <end position="2447"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="2449"/>
            <end position="2548"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="2796"/>
            <end position="2892"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3236"/>
            <end position="3331"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3335"/>
            <end position="3432"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3433"/>
            <end position="3538"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3542"/>
            <end position="3647"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3649"/>
            <end position="3746"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3751"/>
            <end position="3844"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3845"/>
            <end position="3938"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="3940"/>
            <end position="4035"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4039"/>
            <end position="4131"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4368"/>
            <end position="4462"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4467"/>
            <end position="4559"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4561"/>
            <end position="4657"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4662"/>
            <end position="4766"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4772"/>
            <end position="4859"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4865"/>
            <end position="4957"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="4959"/>
            <end position="5053"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5054"/>
            <end position="5147"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5152"/>
            <end position="5248"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5494"/>
            <end position="5588"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5593"/>
            <end position="5688"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5690"/>
            <end position="5795"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="5992"/>
            <end position="6091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="6117" mass="654291" checksum="C04EAAC1224025B2" modified="2022-08-03" version="1">[encoded data, 6117 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ0</accession>
    <name>A0A8K1CCQ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GB1/RHD3-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000757</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ0"/>
    <dbReference type="OrthoDB" id="2135133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10751">
        <property type="entry name" value="GUANYLATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GB1/RHD3-type G" evidence="5">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="820"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1095"/>
            <end position="1104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1104" mass="125984" checksum="F3471785B08C77A5" modified="2022-08-03" version="1">MDNLKSMIFGTKPSAVKWLGMGHSDADNQDHPDRMFVHPDAAKHVLQPLGDQPINLISIFGAARQGKSFLMNLLAGQQDLFKISNLREPCTQGVDLSSHFIPLPKFSALNNCPAVATRDDPAIQVGFVDAEGQGDRDITYDSRLVSPVLLSSKVVIFNWKDSLQADRILNLLAVLARAAQGIELADGDHSKVFGHLHIIFRDWSFVDSSPEEVYNDLFSKEKGRSEEVNLRNLARMHLVEAFESINIWLFPAPVANTANLRDKIRFEQLQEPFQVKLRDLRKMLSTQLRRPMLFSGKPLTARLLSQMMPVLVETLNSDEVIMPESIYSSMVRAEAKATKEAFERRITEYCEAAGIEDLIASDEFEKMLQHDVQVLIKEAMNDMSGAPGTLRREMQAALEEFAAKEIKLAIHTNNQKIAQRVSHEVDVVFENLRSECLHIEQNDVPMRSDLLKHRCKELLAQELNRLEVLPAGTQGRHSIDVEMNRVRQHASVLFDRLEVTNEKAIQKASAAVNERVKTGKVRMTKDTHETLDKIFGARTPVTVATLQAGLEELYRDLIRELKAYVDEHPFMSADFVEDIEDHKSHLAEELNRRYYLEIRQILSEIGFSAKDDLGKEIGSRLEGKLPLEDDEIKRAIDEAVQQVKVLVAQQLQGWTILKHDIAAKSMEIEKLGDVYAYEYLRRNQDLQKDVSIRQEHQQYEDLKSEVIDEFQRELRQVEFPTSEATIETTFTKTIREMISEFLAIETTSPNFTASALFDKLTNECRPELENQKILNRLASEKNHALQLAEKERAMREQESILARKKEEQIAQLQTYVEKSLGERETESKRLQDQLREEADRARQLRDEVEAMRRRTAEIEAQKQMEMSARETALREEMARREEADEMKRELEELRRRAASMEVERSHLQRQAQEDARMQEESRYLSTELNEMKRRAAALEAQKYQLELQAREEALRRQDAEQAARAAANAAALSARAALEAAADEVSPFRYQHVDSGNKRKFSHVQRDVEMEEAPSVTPSVTSGVRRMTPEAIRRAQRIAAGQRPSGSPPATAAERKKRKVQPNTKAPAGNSGRLSALEEARRAAQADLERRIQERTSNLKSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDB3</accession>
    <name>A0A8K1CDB3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Coiled-coil domain-containing protein 104</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000249</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CFAP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDB3"/>
    <dbReference type="OrthoDB" id="97851at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038888">
        <property type="entry name" value="CFAP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532">
        <property type="entry name" value="PHOSPHODIESTERASE HL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BART" evidence="11">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="26459" checksum="512E9833200F4EC6" modified="2022-08-03" version="1">MAATFDAIDLLTRYETPLLKDMEKEDDVLDWVAAYIGSESFQDGVDAFCEEHGEKFKILMTKGGPRSEDLDAVEEEWKQLHTQFVDNAHAQIEAFLESKGFTAEHYKNRCDEEMRLSEERQRHTRLSFFVQLLTACTDYEQFLNLMRRAADPEYYDKKELQYQAEMIVYEGGGPPEYLQQTPPPGTRSGKGVSSDQIQAAHEFLEFFDQNPSATLEELTEEFQKKLQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDJ2</accession>
    <name>A0A8K1CDJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62528at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054517">
        <property type="entry name" value="SPEF2_D5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052634">
        <property type="entry name" value="Sperm_flagellar-bone_growth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919">
        <property type="entry name" value="KPL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919:SF0">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22946">
        <property type="entry name" value="SPEF2_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="605"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1217"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1290"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="923"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1226"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1297"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1315"/>
            <end position="1332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1564" mass="176897" checksum="8441751EE2B81829" modified="2022-08-03" version="1">MSDLLLHWLNHDLHLSTYVTDVEADFASGYLLGELLHRLNHQHNFSDFMNSPIADAKILNFCLLEPSLRHLNIKFDSKVATAIMNGKRDAAANVLYQIKMAAERIRRAPGVSTRSLERTNIHPLHNMPVKLAKPTYDAAKHYFFEHSVRRQVKSLATLKQERDAIEEEQRVQREYRAEQARIQAELKVTKAERLHRAFIHSHFIKTALEETDSPAWRLALEKKHTREQRKAHFYKQLAAHRAQKQEEHTFSLRHSTQRDLDEFERRESSPRAANGSLPARKSVGYGLRSLSATLEQSKPTDNGLGDPHKPNPVGETPELQSNNSVIKEQKQRREKRREHLDRRRKRFLLDSQQTQGQRNQRQALERMETVVARATPREDEAQGEMSKILVYKTIAKENRDLREATYAHRRETDQYEAIDTDASRFELLFAKYNDDWELLVLQQTQREIARQSARAHGNQLLVGIIMQEFIDFALFIAARREDTSHARGSDIFLHDTTWQEYKHQFVRGRLIDPPDESKSAENQLVHHQLIEYLNSFLAPQFTGDYVGAVAKGSNMRSPWVPTDWKFVGACEILEDRFVLGETVKYVRWLAVHYTPPSVVEPAEVEAIETPSEEQSALHKMEPREEGGTAETLPSENQEEPLQPTEEETTPALVPPLRILLVGPPFAGKKTQAQKLAETYELVLISVEERLTQAVDTATSLGIEAQGILSKGEELPPRIYSQLIVEAVSTLLQPRWVVYDLPATKEHAVSLEEALTGFVEPSLIPSPYDHVSILAPGCAAPPLSKTFLHGKSGLDLVFYLNSVDATLLERCLGQLRDPATDTTFHLLTDPPSVDSTDRYRLVHDNVTRYASELLSLQCLSVHDASKDQKTWFQRFDVLRDVTTTQATQGQALAITWPLTVEDVEKQLHEHISAFFQARDDEKIANQASKEAQEATWMLEEETRQIRLHEMEAVITRAQDEVLKAQQVVQQAEEAKAKKDELAELRGHIETAKKGVDVALASARDWLLDEQQRIVNSRTTYSGGLIPPLGSVLAQLWNHMEDEYSHAMKTFFAEQKQQRERVTDHAMSMVESFCKMLRRPDRKQSVLNAFQAQFNAVLEPLRFDDTTKQELHARTDLLQDELCSITMHKHQENDEEVTAMMSDLWLEDTCQYVAVLHQSALQAECDRFRVTLQLLLDGFSAASDDPAQLQCVVDVLKAQPQAVELSVKAFLIAIASDKAPEPAPTPAPAAATGKAAAGAKGAKGKPPLNPVASVSSMEQASSADPLAVDELLLVYDQILQRCEAVAQLILNAPSKNDTPEPPPPTPAPPPTKAGKGAHATPAATPSATPVSSAAKIPRQTIDVATSNFMKAIRYESELMQRRVRALKESALTACEEVTRAIRLVESTLRDANDERKLREEAAIAAVVQYIRHTIEAEHELPYYIDIQPEQVYRFPSTLQLREDTCATVNPRDRLVPRAAVDPPPEIEPRHDFLVNDRQVLRLRTRFFQACFGQEPMHLSLCQTLEVLVPLTTLPDALPRMWRHCPEETLVKICTAFLDESSHLIRIDALLDALIRQDNWLRGFLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDN0</accession>
    <name>A0A8K1CDN0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ras-related protein Rab-21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014544</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDN0"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032482">
        <property type="term" value="P:Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04123">
        <property type="entry name" value="Rab21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000550">
        <property type="entry name" value="ras-related protein Rab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041833">
        <property type="entry name" value="Rab21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="175"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW61083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="284" mass="31198" checksum="D416B17929C80C66" modified="2022-08-03" version="1">MADRSGATRKFKVVLLGEGRVGKTSILLRYIKGEYDDRQVSTLQASYLDKRLMVDNAKVQLSLWDTAGQERFHALGPIYYRDADGALLVYDITDDESFKKVRTWVKELRRIVGDDIDISIAGNKVDLQRNRKVSEDEAKRYAESVGATHFNTSAKLNRGLEDVFVDLTKRMLSRNSSKKKKSALIADDEPMPPPVVPGRPSTQRPTSHSNAGRGGAPRTGRNPSPVADPRVRAGGRGPAPFIADDDEDDGASAPSRMTDGVRIRGTSHQKAQVEAATKEKSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDR8</accession>
    <name>A0A8K1CDR8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDR8"/>
    <dbReference type="OrthoDB" id="92924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53863" checksum="8D36A84295CF073D" modified="2022-08-03" version="1">MKSSLRLPPNALPQLNLSPAEERWVMDEATAVIAETLQREQRFMARGRILPKSGWRVIKSKDDFSVFKERSVMRMFNSTPPPSGAVLLPSERSASAAGAFFVDEIPDDPSIRLSRDHGSMTATRGMWMYTGRGDNEGIIANMKDHNIPMIKGTGYIEGTINDVLYGSLAADDYSWRFRTFYMKDKLADARILATIRRPTSDRAFEFLGIKWFTKESPRYVGSFVQPRDFIVLEANGTGVDDTGTPFGYHIVHSIRLRGVADLSEIGVTRAKMSLCFIIRQASDNKVHIFGRGFSDPRGDMLESVSVGMTADSMAAPANAVECSYAKKLMWMMRHQRRHVNKQTQTSITLVQCDSCDRSQTKLVTCQVCARVICSRCTVQRKVLVDITMEGVITERSLAFCFGCVVESKKITPGRVARDSYSNNFYPAEISPNESALHVTTPTDRLSYTTSPPAPTSRPPSVSGHNVSVCKKAKSSPPPAPGIVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CET5</accession>
    <name>A0A8K1CET5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CET5"/>
    <dbReference type="OrthoDB" id="101421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035473938" evidence="1">
        <location>
            <begin position="22"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="485" mass="54585" checksum="9933E49561363F3B" modified="2022-08-03" version="1">MEVSKALVLSLLLGFEDLCSADEWAKAFYTASEDYEDPESVHTAHDTVEITVSSSVVEVVRLVIPDLPEYKTFSLNLYGLLDFCQQRYPHEHFVVVRTWLTRTDTSHVFRVWLYEWIASAQGVKTLSIEPSGSKEAVVLATLREQDQRLKRRLLRYLDEKMAEVDGGVTEPQEMATQAEQLLVFYWNHWRELAPTSLLSAVKLVAALANQNQNATQQEKIFTLIKWGRALKPVLFEGMVKYTTTLKLFVDVPVHQLALSSVLTKQLRGIPSELLLATRSQLVQVANHLQDACQRKMKHVFSQSGGLMPLEDSASAIMSSEERCLVVAELAQDLDVVLPDVFADLLAVWVRVVGPLLARATNPEKEDDAVVMTLGSLFELLCWRADVASCFLVLSAIVEYGLVKHQAWHHHPLLYQKVVGLLSEAYTVQGDVTKRWILRMALQQLLFESDRRVLVHSISQIQSGLPTCLLSLTTQRLGVKPHCTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF56</accession>
    <name>A0A8K1CF56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF56"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="54352" checksum="63CC81EA65D2E9E2" modified="2022-08-03" version="1">MKTLRLPPNAIPPLKLTPEEERWIVNEAAAVVAETVQREMRFMSLGRIFAKNSWRGVKSRDDFTVYRERRVMGMWNSSSDSGNPTTDSMSTDRSISSSEDFHDDSSDEMRICREKRVSKATRGMWKYNGHGEDEGIVAGMKGDDIPMMRGAGYSDGSVEDMLYGFLAPDMQSWELRNFFMKEKYADTRILATIKSPTPDKMFNYIGIKWIAKDPPRLVGSLVNTRDFLIVEANGQGVDEIGTPYSYLLMHSIKLRDFPDLSEIGVVRAKGSVCFISRQEGENRVHIFGRGFFDPCGDMGENMAVMMMAEMMVMPATAVECSYTKKLLWMIRERRRRSKKQTQSSSYTTVQCESCEKTPGKLSRGNFSPCKACERVVCGRCTVQQKLMIDVTSEGEVIERSFPFCSGCIVEAKRLSPGRIMYDVLTNEAQLSRHDSHSSNSRASTPSSAHTRPPSVTETPGSTKASRATEKRPTPPPPAPGIVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFM7</accession>
    <name>A0A8K1CFM7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFM7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="612" mass="65647" checksum="CD7CF7BE3C259C49" modified="2022-08-03" version="1">MSADQQDVDLYCRSTTRRNARADVFTLRGPKPDAIRVRAKIAKMEISIAFASRCFKLRLRTTCLQEYEHWFYLLILSATNVVVEVPPQVLTKVSAATHVDVDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDGDLQLEAVANLRIEDEDQGDAQDDAQDDAQDQGHDSAPISLCWSTADSYETNSDSDEADENVFDDHEGGDEEEDNDDNDDNDDNDELEVDVEDNKDVEARIQPQPQPQPQPQPQPQPQSPSPSLVFSEGDPDPDLDLHLHLHRGEEDAHADNYRGHGDYYTPSSNAWERYLVDSNGDGDNDNDQDIGTATKRDQSSLWSLDDLVSSPRESWSAFLDADADADTTDANAGESEGNSDNDNDSDSDSDGDGDDDDGNGNGNGNGNGNGNDYYVVPEERTPPYIWADRFLPDETLRPLTRDSDGSIADPPSSPRAVYVERHRDDPDVNFFGRPSHEITATSRSTFYAWSPRGPNVEGHRVSASASVDVGVDVDVDVDAGAGTGTRSAQTTATARTHATTTATATAAWTSLRQRLRPATSAANSAVSRAPQAVSYVRARLAQARAAIPSAKRRTANRTSNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGD3</accession>
    <name>A0A8K1CGD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGD3"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01161">
        <property type="entry name" value="DUF1767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="261"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="457" mass="48706" checksum="5444CA03C49562AF" modified="2022-08-03" version="1">MSRLLSYQGVDPAWEERERSAFAKHSNRPGATVGQFLLGRFLEEDIHVSCKPMLPRDVVELNGKVLKGVCILQIVDVVNIGASFEHRTENSKGPSRTLKLCLTDGYQVISGFEYQWLPQLSVNTPRGSKVAIQNVAVRHGMLLLTPSTCQLVGSSGEPVEADKRKTKGATKDPTAGAYSAALLTTGSIGGPAIKPSGGTPQKASMDRDRPLFIATSGEQSPIIPLLPVNEDCAGPDSPKTSLQPQLTLQSTSKPPSIMTKVAIIYYSTYGHIVQMAEAVKEGVEKVEGVTATIYQVPETLPEDILTLIHAPAKKDYPIATPDTLKEYDGILFGFPTRFGSQPSQIKAFFDGCGGLWAAGALVGKPAGIFFSTGSLGSGQETTAYSALPFFAHQGMTYVPLGYRSPLLFNLEEVHGGSPWGAGTIAGGDGSRQPSQLELDVAKVQGESFAQVAKKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGH8</accession>
    <name>A0A8K1CGH8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGH8"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="34445" checksum="AED55A2D43763050" modified="2022-08-03" version="1">MSSSTREWRWRVWHDEDCAWLSALEARNKRLVARVSSAASEPNRPSERAIPQIIHQIWLGPHKIPPRCVNWMNSWTQLHPDWEYRVWRDADVTRLSLKNQSAFDAATNFGAKSDILRYEILEMVGGVYVDVDTQCVRPVDTLVKHFAFVVGISNTGCVEINNGFIAATPHHPILTHLIDSIQQDFKRPRLNTATLSLIAQMCGPGIGLPGQLLPPDSQSNPMETIERTGPGLLTRVFMQAIGWSTTERGFLSDDEQEDVVALPETYLYPLPNTLSTISSDELSVQLPSTAFTVHYWERSWLPSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGN8</accession>
    <name>A0A8K1CGN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005322</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGN8"/>
    <dbReference type="OrthoDB" id="66546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF33">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="714"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1043" mass="119474" checksum="59B91857EEA3796C" modified="2022-08-03" version="1">MAVPAWTATQWRPHVRPLCERLLRRHAEDAEDEQLLRVDRVVTQLYNHRYMETTPNQVKQQVDEMVVKFQVHSLAERGVKLQELAQHCDFLVLRTLLELADAPTKVSASRIQVDTKTPDELDAIWSRLLKEGKDAQLKREAEAALAANMEKELLQIAWEDDWWHEREAKEEDDDDDESELDDLEEDEDDDDVDMERMDPSIEDMGIAVDVLGRKDDEESGDVRMPETDGEAGPSDDEDEDDLLLRYYRPVVSVHSQTEANTTPMDTDTDESSKREHQSFALDVPTLLYPALEASHYKSQAAHSGTSTASVQSVEPRRVVQEQYLVESIFHALHGIESPVFEFRRIPVDWMFHGDFETSIVSVSSLTRRGLALSHLSPLTMDSVLQKMAQAASDLQFLRELVGFILSTHGDRSQSSTAAEGLANVLAKYVWKILQHVGSVKVAMEKSMEPTFDPSDIALPTLLGTLGRLKELFTLVSWLSGIMTYCFGSFRQLRRHEVRPAELSSQLLTALHEQLMLAYIEGSPSVQQDSQWSRYDILLDLFAGSLCPYLDGLERMLFRMNHADTIPLHPELFFIAPETSVLSPSNRRHKESFDEAVLALMPFRVSPPLVPSFFKSLIPTMSDALLSRQMKNRYLHQRNESSEHEPNSSQSTLSERFLQDLSTLQFSSSAAKKDVHMSPFKDLVERCVCAHIRNECLEISGTIAQMFRDRLHFVQHVEALRHFVLMHEQDVYTTLVTHILEQIQLYPVGWADSERINQVHQNAIQTMHEEFNLSDQERAIASRIRITVDIEKLQLFEPSSAVNILAIRCLQFGFTIAQPLSVMFTSAVLRKYSLLSSLLIQVKLAELVTTKLKLSLRHRRCSRVVDDVMREQLVHVTDMLQFTRCILHYLANQMTGPLWIQLKETMQHSKSVAEINAAHEKYLDQMQNQFLLLPKHEPVMNVVLGALGSILGYVRKAEGFIRLMDRNLEQFFPEAATKRPVKEYSPEFQKHFIGFKQEVRPELTLYTRSVRMITVMLDGMVKHGASPHIRELFMLLTYNNFRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH36</accession>
    <name>A0A8K1CH36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="9">
        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="138"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1144"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="292"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1053"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="140"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="177"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1150"/>
            <end position="1163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1354" mass="149693" checksum="F6D72EA9FF5A801D" modified="2022-08-03" version="1">MSMELELGGRVTYGVSGKTGVVRYVGEVETLSGEWVGIELDKPEGKHNGELNGKVYFTCPPNHGVFVRKTQVKPLNARTPAGSPTPRSAASTRARLAGASASSTTASRLQQMRDRRVSGVGVGTGMASERRSYAVGLGGSAASTRSTASTAAPSPVVSSTSRLSTSGAATPPPSGPPSVRRTPSATSTASSGATTPSRLPLDPAARRPLLNRRPSLSTPSDDLMEARARIAKLEEELEDRNRHVEQLNQNLTALRESHERVGTESRGETPTEPAPTPMEVEDSGETDESVWLEKIEEVRQEAEEHVRNVRAELEDFIAQLQSEHEELVDELRLENATQSSEIKSLEAEVAQQKSRIAQFTTAEQKKAEEVAHAVAKTSAGARKVEALEAQLAEFQEMIETLTLDKETLEMDKEIAEEHVEELQAEMEKLKSSIALASSAAERVVSSTSATELAEENMKLRAAVKALHDRGAEEKNELNKKLRQLQRENVELVALREEVEILTTKRIKLEGEVEELKELLDVANAYESMVEDLTEKNLTLGEKVADLETSVISLEALKEMSEEMEHQHVEYEGELNREIESLRASIQELKNEAADQKTTVDDRDRTIARFRDAMNRSREEINQLKAQLRAETGELESLKGTAHSALNQTMTLRVLAASARENEAEAAKQKINAEQARLENAFLRAAVPSSIFSEMDQKVLRVRLRLGRIAGKADILLQYLKKDLDGLTQQEQQEEGAATVIDSERTIQQFLLGEKLATLSCQAKEDLFVLDCHLTTAEEYNITCGRLDTNQVGLLEAALDSGLIAFADGSLFVSRSGEASVYNRLLSTLDEWRSSQQTMEQATEGFPMRCAVVKFRSRKSVMTLMFSFAMMVTYMNTMKGFVQSPDVQIASEAKQALTNVLSTIIEDFGGLLKVAQQLHRRGEMDLAWSDEDLDGSVAVGGDVVELMYAYAAECQTLWSVIQEQLSVSKLQAGASDELMAFADQSLLSMLTSLKDRLASIFKSVCRGAFTDAVTSRSRDRIDMPETREGRPQWQIRAQAIHNELLNAAGMRVSLNEANELCQALHTRVRELERADSQHRVVAQKLESEILRLNGEVSQTTSEKTRLEEQLGREREQFHITLDESHKEKAALDNLNRELRKQLKRSSDVGLNISSSSSRGKSALNQGDADAFRKAFEHLHGELHRARATLAKERMDRVLGPLVPTRPEVVATPSDKLVKCAKEVSKFSAHVKTQLSMPRMVDLTKTTASARSQLVTKQLEHAKMRQTLADLRSRLSAAVREDGWSGDVVSAISRGENVFGWRPPEMERPPVLLGRVTLRPPVDKDAMEDISSGSPQPVQLVLNQSQVQQLTQRLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHC9</accession>
    <name>A0A8K1CHC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">fumarate reductase (NADH)</fullName>
            <ecNumber evidence="6">1.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NADH-dependent fumarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHC9"/>
    <dbReference type="OrthoDB" id="10252157at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000007">
        <property type="entry name" value="NADH-dependent fumarate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF7">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="9">
        <location>
            <begin position="51"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00050832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00077246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="506" mass="53143" checksum="3EE2D352F66BA7EA" modified="2022-08-03" version="1">MQMAGGGSLVGPIVVAVLSVCCVVYLYIWSTIMAGANEAATGSNAAQIQADVVIVGAGLAGLSASIEAATLHPTGKVVVIEREPKVGGNSAKASSGINGAISDDDYPVFEQDTLKSGGGLSNEQLVDVFVKKSPSAIEFLKQNEVDLSVLCQLGGHSAKRTHRNKSGPNVGFAIISALQKRIAQISNIEILTGSTADKFLVDDSKSKVSGLQIKQTDGALVHIRSPAIILATGGFSSNQQLLKRFSPGMEEFPTTNGPTAQGDGILMAEELGADLVLMDKVQLHPTGFINPKDRNAQQKFLAPEAIRGSGALLLNTEGKRFVNELSTRDLVSQAILAQPGKTSFLWLFEGAKALESSLGFYKHIGLVKQVASVREAAEYCHFEADDVLIQLNAYAQIAAGETPDPFGKTVFPYPLEHIDTIDSPEDIHVMEIAPAVHYCMGGVKINAQTQVVRADGAPIAGVYAAGEVSGGLHGANRLGGNSLAECVVFGRIAGQQAVQHVLQAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHS1</accession>
    <name>A0A8K1CHS1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPT6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="995477at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09928">
        <property type="entry name" value="SH2_Cterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.850:FF:000001">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000081">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028083">
        <property type="entry name" value="Spt6_acidic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028088">
        <property type="entry name" value="Spt6_HTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035018">
        <property type="entry name" value="Spt6_SH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14641">
        <property type="entry name" value="HTH_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14632">
        <property type="entry name" value="SPT6_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="SH2" evidence="6">
        <location>
            <begin position="1290"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1480"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1483"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1501"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1519"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1531"/>
            <end position="1549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1569" mass="179821" checksum="4B09E53443A750F1" modified="2022-08-03" version="1">MASSDDERRGGASPMVSDSDSGAEEELKNKSKKRKLTKPSSKKSKKKSKKSKVIEDSDDENEKRPKSSFIEDEASESEDGKEGDSDDSDDDDDDGDKNEYEADGFVVDDMDDDESDEDGGRHRRRRKKKEKKLRRLKQKIDDIDDEDLMLVRENLGMDTGPARSDSEDEDMDRSSKKRKDDSGLMSRELSYRMFGDSDDEEEEAAPARNNNNYMGADEYESDDIDEFIVDDDEEGREGPRRRRKQVSLPASMQGPSVYQMGEAEELFGDMEGFLEATRGALSGEGQAAPKSKKAALLEKYEPDVLKEHMMTPEIISVRDRDLPERYQQLFDGRQFPDAEDRADESEWIGEALKNKMGDKYISSGEVVSAIDSVLRFYHDEKLEPAFVQRYCKEFWKPAGLRTAHLYEILDLDIKWDKLDRKRKSLQAIMQRTVDMSSAKESSFVRECYNRMFRVPNEKCYQDLTEFFALDMDSSKDEASSDRKYRRPVRRNFYQICTKAGLRKLANAFTMNATVLGGLLVGVDHDESVREVPTPQDSPGMFGQSFTSKEFPTVDDVMRGARHIAATKIAAEPNVRKCMRDLFRQNALLFTQATTKGQEEIDEFHYAHGLQYLEGMPISEVFAHGDVWLRLTRAEKEGLMTISITNDRLQDLIDPLNAVFMDGSNDADEEWENQRYQTLQEAISSFMVPSFENELKRDLVVSSREYLVKECGHRMRERLLVRPFESKDGTEPFIVSIWVEGGPDAIAHMAAIDENGELVDKTQGYCRREERHIRTLTNTLFRFLQEHPRTQVVVINVSGGMKCMDMGELVDAVRHELGRNNANRFGNNDGKDWMEILFLKDDVATMYSRSKRAELEFPEESEPIRAAIGLGRYLRSPASELSAMWGNVTLDEPTRGRELLYLNVHPMQHSLGKEMLLREYDRVFAQVINKFGVDINLLANHKHTSYQLQFICGLGPVKAASLLDKVRAKSYIERRQELLSKGMVGKIVYRNCAGFVRIRERDALKEAPLNPLDDTRIHPESYYMAVKMCGDANNNSTIDMYDPNQYSYAVEETMFQSATAIRGKGSSRTERLGDNEIQDALSELDLPAYASRLEQQKKGPKLLTLEYIKRELRYPYFDKRHPYQMPREEELFVLLSGENKDTFQEGIIVPCTLLHMAGGEFVRVRLQNGMRATLKKDLLPDYLTDDHGAYVRNNGFPKGLTVNARVLCIKKDPNGRFEAQLGCNRRALMDFEMTFNPEKLLPYARRNQIVDDTKIRLDKLLNRLVLEDEKDVYSSDRRGGQARRKKRQIGHPLFKNVNCQSAMQELRKGTEGDVVIRPSTLGSDHLTLTWKMLDGVYRHFDILELNKPSEARLGEKLMIKEETFDSIDELVARFVDPMNDLVREVVQFKYFKNISLEEVHEDLIKQKKAHPSRIPYIIHLYNKFPGCFSITFIARTTPHSCHMEVKSGGFRFFGRIESSLLPTLNQALQFFKMKALVAQPTQPSRSSHSSSSYQRPESSNSVPFAQQRPPSSSSGNYRDSGNGYSHSSGSGDRYRQESRFDSRYDDRRDGGGSYSRYNDGGRYQDGGRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI45</accession>
    <name>A0A8K1CI45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI45"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="31291" checksum="7E7E7930E59A0747" modified="2022-08-03" version="1">MHTTIMASRIPSVRTETRSTDSVGSAMGEQVLHLLEFVDLELLTSSGPVVEDVRYVLKVHQRRARAVWKYPRSFDEYVAFNGRMLEALQHGHFCDAGCPWLHGFLVSKFPAKTTLLLSASSHTVVDRRRRALEEVLQTLRKFLLNRINYSCPRIKYHVAEVFLDFVYGGVIDDHRLLEACRGPVSVPTPPTSSDSSRSLLSVLSRGSSMDEVIIPELKSSSSVECEEVCTLCMQLVTTQDVYAMRLRCGHRFHDECIVPKLNEELRCPTCGDGQRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI54</accession>
    <name>A0A8K1CI54_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Histone-binding protein RBBP4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI54"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000512">
        <property type="entry name" value="WD-40 repeat-containing protein MSI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059104">
        <property type="entry name" value="Beta-prop_EIPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23609">
        <property type="entry name" value="Beta-prop_EIPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="8">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="185"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="232"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="EIPR1-like beta-propeller" evidence="9">
        <location>
            <begin position="237"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="278"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="322"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48998" checksum="2EE2825A3A54DE7A" modified="2022-08-03" version="1">MSSTEADGVVAAAVDPRENDPALKEKLINEEYKIWKKNTPFLYDLVMTHALEWPSLSVQWLPNSHTSAGDDYSVHKLLLGTHTSGAEQNHLMVAEVRLPLEDTEIDARKYDDESQELGGFGGVSGKVEIRIRINHDGEVNRARYMPSNEFIVATKTIHSEVHVFDISKRPSQPEEGAGSEPDFRLLGHTKEGYGLCWDPHEEFHLISGSDDAVVCEWDIRNAGKTVEPLHKYTGHTDVIEDVAWHMHHKKIFGSVGDDKKLLIWDMRSASYDQPATTVYAHTAEVNCIAFSPFSEYLIATGSADKKVNLWDMRNMKAKLHSFDGHNEEVYQVQWSPHNETILGSCSADRRLHVWDLSKIGDEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNDPWVVASVAEDNVLQIWQMAENIYNEEGGDEEDEVAEDDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIX0</accession>
    <name>A0A8K1CIX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_005630</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001145">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="1388"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="2017"/>
            <end position="2242"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="2380"/>
            <end position="2537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="2842"/>
            <end position="2914"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="3158"/>
            <end position="3185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW63012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="4091" mass="460865" checksum="5DA5A808B95319CD" modified="2022-08-03" version="1">MDPPSSTVERDGAKRMHRRGTGLGLGPQANHILQRLYEPKLGPQSGHNGKPSATPSTQASTGSHSPLKPKRLMKKTTSVETLAPSPSILLHPALHQASQKTWKLQERQHDSVPPSTASTASLRAASPVRDNQRQDSPTRARRGRTTSASGSTASLSFTASLNLDPRYLREFRSGNFLYLRKRRDSDLVMYDLEVVEHFAVDRSDYFTMSLEGVTHFTTTHSEFWPLDKWELEYARFMQMLTVPFFQKYKLWKNFNVWKQCVRAFKMRHAKKALHERLFLLQPSLQITLLHLRALCLDVATLELVRFQPKRTYSLKEFENEQRLTRDQVTERLANFSQQSLQLCVQACDDVIDRFLEANKIAADHKMTFMERAALRKECRTLTNFLRLTDFLTIDATIQLTVHSFQRLYDVLTAGKVQAAAPIIRTIPEPAKPSGKGGNAATAPVATPFTAVFAVSVQMESASASISAIPGHESWNHALQRALKEALRMVETPARHLGHESLAPYTTASAEDEGKSVWSIEQLNVALILNEDVKFSMLTNDIFVALDEAFEAVDEYMDVFAPFHSIYSENQGQIVRLMDTYAAAPLEFFTESIEKYKAQGQSFIDIPDAATVGIFRVDSSEFKSRLLPNPEQCVQGIRALIPKLMKQTSTALLETLNDLSPIAFSTPSTPESFVNKVVHMTHVTNVLPDLRTRYRRVYEMGTLMDNYDWRVPDDIKEDIILMKEGVLSLEGTVMKFEGEVDSETARFSQVILDSFTPLTRQVLSVREKLDHPKLSTIKTPIQEALSFLQSQENMLNQLVDEAKKLTLFQTQLKQPVSEITEMNDVAAEFELKMKLWGGLSEWQKLTVQYADTPFDDIDVTSIGKHVQTYVKVAYQAQKAFPGNEAADLLQREVDKFKLVLPAVSDLRSPALKDRHWQQIDTLLGFSMRGQTEMTLGKLIAKDVMRHSDAISAIAVSAQQENVLEEMLKKVTDAWATTEFEVKPYKESKDIFVLGSVEEVTTKLDDSIVTISTIMGSRFIGAIQDEVEGWRKRLVTLQETLDEWLLVQKNWIYLENIFSAPDIQRQLPDASKIFQHVDASWKTIMRRTFETPHVLTAGTFPGIKETLQQHNTHLDRIQKNLEDYLETKRMAFPRFYFLSNDELLEILAQSKNPQAVQPHLRKCFENLVKLDFGDLPGSVDMLAMISAENERVPLGKNLKARGNVEDWLKSLEVSMKASIYKLMKVGLLGYDTKARADWVCDHPGQVVATVAQMTWARSTEEALNTTVGDPVEEMHHWFGRVVFELNELIIKIRGHLTSLERKVIVALVTTDVHARDIVESLWLEKVDSVGNFIWQQQLRYYWDPQADDVLIRHSDSVIPYGYEYMGATSRLVITPLTDRCWMTLTGAYGLKLGAAPAGPAGTGKTESSKDLAKAMAIQCVVFNCSDQIDYKMMGKLFRGLSQAGNWTCLDEFNRIDIEVLSVVAQQLLILREGRLQGKEHINFMGIEILLKDHHVIVTMNPGYAGRTELPDNLKVCFRPVSMMVPDYALIAEIMLFAEGFGDARTLSRKMCKLYILCSEQLSQQPHYDYGLRAVKSVLVMAGSLKRANPEIDEDVTLIRALRDSNVPKFLADDLPLFHAIVVDLFPGVFIPSHDYGELQTGLEEEIRKAGLQPVPTYITKVIQLFDIFNVRFGGTLVGPTGAGKTSCYRTLQSTMTSLRAKGSKNPVFQTVHARVLNPKCISMGELYGEFNEVTQEWHDGLASTIMREAVADETEEIKWTVFDGPIDALWIENMNTVLDDNMTLCLANGERIKLKYEMKMLFEVMDLAAASPATVSRIGVVFMTATDLGWMPYIQSWMQQELTPPPRAFPPALLQRLESNIRLYMDKTLQFMRKKAVELVPTVDMNLITSFCRLFTALFSPDNGIAYAAMTPTDPSVLELLDRVFAFSLIWSLGATMTVDLHEGFDVFIRELFVDAKLQLPNAGLVFDYFVDPAMQRFRAWQEIVPVFQYNAKLPYFKLIVATPDTVRFTFLLRVMMAHKTPAYVTGVTGTGKTVIIQDLLRELQEGPPSTTEGEAPPPSNYMTMLINFSAQTASLVTQLTIENKLEKKRKNLLGPVAGKRMLIFVDDVNLPAVEEYGAQPPIELLRQFLDFGGFYDRDKLFWKEIADTMLLVSAAPAGGGRSHCTPRFVRHFHVLSMYPASEPSLKLIFASILGGFLEKFPGGVKAMRDGVIASIIEIYNRVSLELLPTPSKFHYTFNLRDVSKVFQGMLMITPSKCQDTDAMNRLWVHEATRVFQDRLNNAKDQQWYEELACGLLARYFNCNWQRETLFHAPCPLTFGDFSKPGAPQPLYESCTDLTKITKILDDALENYNVSFANKMQLVFFRDAISHLSRLARILRQPRGNAMLIGVGGSGKQSLARLAAFMVDAKCTQIEITRGYGTNEFHEDLKKLMLSAGVGGVSTVFLFTDSQIVDESFLEDINNVLNSGEVPNLFPSDEMDRIVNDMRPIVKSMELPETRDNCISTFIERVRDYLHIVLAMSPVGSALRVRCRAFPSLINCCTIDWYMNWPREALQSVADRLLAHVSLPSEDVRHALVEMCSTVHTTSSDFGDAFLAQLQRHVYTTPKSYLDLIGLYLKMLQEKRTILQTVKNRMEVGVKKLDETNGIVDSLKSELILLQPILQQKAVEAEELLKRVSVDQQAAAVVRARVAQDETVVAKQAEEVSIVQADAQKDLDVAMPALNNAIKALDSLSKNDITEVKSFAKPPAAVETVMNAVCLLFNEKQSWDSAKKVLSDVTFLDRLKTFDKDNIPAPTLKKLSQCVSDPSMSVDVVSKVSKAATSLCMWVHAMDVYSKVAKEVGPKRENLERMNQKLADANGILQQKRDELRAVNENVAKLEKQCQDTLDEKNQLARDAATTEKRLERAEKLISGLSVEGARWKESVAFLSQSILNLIGDTFLAAACISYYGPFTGAFRQRIVEQWLASTQQAGIPCTASYALATTLGSPVEIREWQLNGLPTDSTSTDNAILVTRGERWPLMIDPQGQANKWIKKTNGTARLEVTKMTNANLLRSLETCIRNGKALLIEDIDEALEPALEPVLQKAIFKQGGRLLIHLGDSDVDYDPSFKLFLTTKLPNPHYLPEVYIKVTVINFTVTMDGLEDQLLGDVVRHERPDIEEKKNRLVVTMAQDRKQLQEIEDRILKQLSESAGNVLDDQDLIDTLQSSNATSKVIKERVLESETTELEINRAREAYRRVATRGSIIYFVVANLALIDPMYQYSLPFFQRLFNICFDEAPKSTSLPQRLQNLIDYQTRYIYVNICRGLFEVHKVLFSMLICCKILLYAGRITAREWSLYLRGASQADRSTQLRNPMPDRISEAQWDLLTELETLPTSFKAVGDDPDDTEPILGFAALCMSLTQETQDWLAWLSHPSFLTAPCPAPYEEALNSFQKVLLLKGLAEEKVPQAILRMIATEMGEDFGKIAPTSMEEIYYDTDRKTPCIFVLSAGADPTGMLLRFAKEMAFIDRLHLISLGQGQGPRAEKLIETSQISGDWVLLQNCHLAKSWMPKLEKIVEDLAQRSDDECVSTFRLFLTSFPASYFPVTVLQNGIKLTNEPPKGIRANLIRSFNTLATEDVLDAFRSLGTFDDGLEKDVAWRKLLSGLTFFHAVIQERRKFGALGWNIKYEFNDTDLETSLASLRKFLEEQPVVPWDALRYVTGQINYGGRVTDDWDRRCLMSILSNYYTPSILEPGYGFSQSGIYRVPSDLAHAKLLAYLNDLPILDNPELFGMHENANVTYERNESMNMTRIILSLEPRDSGGGGGRSNDQRVLDLAASIQENLPPNLLVEDAGPTTFKTREVAGTVVMDSLATVLGQELVKFNTLLKRMRSSLVDIQKAINGLIVMSSDLDNMYTAFLNGKVPQIWAAVSFASLKPLASWVKDLLERVVFFRHWLMNGEPVVFDLNVFFFPQGFMTGTLQNFARKYQVAIDSLAFTFTVLDVESAEQLTESPSDGIYVDGLWLQGARWSQSRAKLVEANPGEMFSPMALVHFLPAANVERSKADYPCPVYKTSVRQGTLSTTGISTNFVIAVYLPTDKHPDYWVMNGAAFLLNLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK14</accession>
    <name>A0A8K1CK14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease III homolog</fullName>
            <ecNumber evidence="7">3.2.2.-</ecNumber>
            <ecNumber evidence="7">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="7">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NTH1</name>
        <name evidence="10" type="ORF">Poli38472_002598</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="7"/>
    <dbReference type="EC" id="4.2.99.18" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK14"/>
    <dbReference type="OrthoDB" id="2099276at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000001">
        <property type="entry name" value="Endonuclease III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="9">
        <location>
            <begin position="114"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="315" mass="35094" checksum="8041C19F6CD9C7E3" modified="2022-08-03" version="1">MANPFARFALKRSRSPSQDEAEQADVKLVVNGDDGAATSEAVTHVKVEASALNQEQESTEEPEDNRLWLLKQLIQARREGPPSAIDLYGTQACVASTAVDDKVKRFHILVAALLSSQTQDPITHAAMQRLHTELSSAANPQGVTVATMRETTTDRLEELLKPVGFYRRKAEHLKRVVETLHTRYNDDIPRQLSQLIELPGIGPKIARVILLLAWDQVDGIIVDTHVHRLSQRLGWTAHRGQPVKTPEDTREALEDWIPRAYWGDLSRDVVGFGQTVCVAVHPHCINCPLAPRCPSAFKCEPPTKKRKKTTMTVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKG6</accession>
    <name>A0A8K1CKG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKG6"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019396">
        <property type="entry name" value="TM_Fragile-X-F-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568">
        <property type="entry name" value="FAM11A, B PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568:SF9">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10269">
        <property type="entry name" value="Tmemb_185A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="44271" checksum="A5163CF0C4ACFE39" modified="2022-08-03" version="1">MADQAREEKVECTPFGEPDVELSRSQSPGEAVTVDVQPEEKESDRGFQKAGQAEKQYEREMIALAMALRANYALGSSSSSFEDDEVDESEWISLAASMFIYGAMMAVFLIIPIFWCLRVDHIVSWNWAVVFIPLWVIDILLYCVIGCAVLIGDSVLEDHPYPSAYKLFMFTKALLLLLTQVFVVQKLNGDIDWSVVYVLMPYFVFDGVTVAGELLKALVLYVPDASHEYTQPGYVGLKMTLMTLTTALSPVVIRLVQILLIALRIDGTLGNTSWWVVFAPVWISFEFTLLVFLTNVVRLQVLIAFFSHLKLFSPHFLVLAFIGLCLVMAPFFVLAARLQSGSFSSFYILVPYFVLAGGLLLGAVGIGIKLMREEAASTSRLPCEAPLVDSSSKVTYSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKP5</accession>
    <name>A0A8K1CKP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKP5"/>
    <dbReference type="OrthoDB" id="74783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUSP" evidence="2">
        <location>
            <begin position="44"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="31291" checksum="BB962CC296F6DDFC" modified="2022-08-03" version="1">MLKLVSSWRSREEHEDEELTGLDLESGISGDALASPRSVGFGRPVAEERRRLEREMILRHDTRELKRGEAWFIIETSWLDAWMAYILSEDDPDCPVVKPGPLTNYTLFDPKEYCLKRDLVATKHYRGVNPMVYAMYAELYGTAGAKPIVRWTLDIYATPVMIDDVKEMLHGPELKARVEVSELNDMFDFEERPDRSQDETWLYRCCCRCEFLVPCLGRLLMGPTYAKEGEDKKKKKGKKRRKKRRSYDDDDEEDDSSSGEDESETRGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLB2</accession>
    <name>A0A8K1CLB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013014</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLB2"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457178" description="Peptidase M14 domain-containing protein" evidence="11">
        <location>
            <begin position="21"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="137"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="48377" checksum="50F017B2DE4CAF3E" modified="2022-08-03" version="1">MKIFQTLSFLAALVVGQIAAEEAVAKQLYHVTVPKVVFDLALKEYGAELDVWDASLVESDKIKADIYATEESINKFRGGKTELREASPLVKIEQDVVDMPMLIKETAAAKATCSSRTSRHLQAINATNYVNNAFFDCWRTSDEVYSFLDTLVKENSLVFSKIANVSTTYEGRTIPGYKLSTGGSGKKAIYVQGLIHAREWHAGSTTFYTIAALLDGLNNNDSTLKPLVTQYDWYFVPIVNLDGFIYTHSSSGDRLWRKNRRKINTRTYGVDLNRNFGPQKYFGLGGESPSAQTYPGSAPLSEPETAGIYKFIKTLPLAGALDVHAYSGLVLRPFGNQRAQVPAPWGTKLKTLGDNVKKAIQVNNTYTYTSQTAAELYLSYGSFMDSIFLEFNNTATLSFEMEGNNFVVSESVIRPGGKHVFQGIVQFARELTAYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM74</accession>
    <name>A0A8K1CM74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM74"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000068">
        <property type="entry name" value="STE20/SPS1-related proline-alanine-rich protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="42665" checksum="A5327CC39DE70457" modified="2022-08-03" version="1">MADEWPTVASDYQIIEQIGQGAFAKVWKAYCIPKKTHVAIKIMDLEKITTSFEDIRAEVQTMKMTNHPNVLKCYCSFVHKDQLWLVMQLMNKGSCLHVINLLKKKSMGEGLKEEFIAVILNEALKGLQYFHENGQIHRDIKAGNILLDGEGHVVIADFGVSGWMMEGGDRRKNRQTFVGTPCWMAPEVMEQVHGYDYKADIWSLGITALELAKGYAPYARYQPMKVLLLTLQEDPPSLKTYDDDSAQQFTRHYKDMIKLCLQKDPTKRPSTSALLKHNFFRKAGDAAFLAQSLLGKLEDIGETSMTAGVTDALPGAGPLYASGTKLPAGLQDKEDSKYVPGTTWVFDDNEDGDAKDKPALTSDDFADQFNMLTGGEEFRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMC9</accession>
    <name>A0A8K1CMC9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Nuclear receptor coactivator 6-interacting protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">PRIP-interacting protein with methyltransferase motif</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Poli38472_003952</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="20">May form homooligomers. Interacts with CREBBP/CBP, EED/WAIT1, EP300/P300, NCOA6/PRIP, PPARBP/PBP and SMN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Cajal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMC9"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000066">
        <property type="entry name" value="Trimethylguanosine synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="18"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="171"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00064494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00079339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00081504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="TMW66187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="445" mass="49618" checksum="90E99AB5BB57991B" modified="2022-08-03" version="1">MVVTEAWLVTKNGQTIVLDAKTAKKQSKKKRNTKRKANSSGGRQRKKARVDWDQDTSALQSIGEEDGDAEDPNAQLFADAQSDLMEEMAAAGFGGELPLSFGSTKSQPARSSKKRRRVYDEVHDTTPVGAEDPVKQPSPVVVEHVPTPAVVEKFHVKYDSDGEVVERSTEVVELPTEPTPSESFGHNVVENDENGLHNEPAAENGEEPPVTPPEELDQTVLKFWKQRRTLFYQYDDGIHLDHESWYSVTPQAIAEHIAQRCACDVIVDPFSGCGGNIIQFAKTCRQVIAIEIDPEKIRMAQHNARIYGVADRIEWINGDATEILPKLKADVVFLSPPWGGMNYNRNQFDIDKMLVGDTTGTELFQMARSVAPNVVYYMPKTTPVADLEALSPDEIVECEHLHLNGQLKVVNAYYGELVQRKTIRDESEMAEQTEEGVQVDETQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMI9</accession>
    <name>A0A8K1CMI9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_003999</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5980013at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051986">
        <property type="entry name" value="Innate_Immune_Apopt_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16295:SF10">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16295">
        <property type="entry name" value="TRAF-TYPE ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRAF-type" evidence="8">
        <location>
            <begin position="1193"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="7">
        <location>
            <begin position="1556"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="1193"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="375"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="815"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="893"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1121"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1225"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1396"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1488"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1622"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="551"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="732"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="815"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="847"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="950"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="963"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1126"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1229"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1396"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1430"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1488"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1525"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1623"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1651"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1688"/>
            <end position="1707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1726" mass="189102" checksum="0EF8BBB4000FFB18" modified="2022-08-03" version="1">MDWEANLAAIIKHTDANLEQQFRQFADLSGDLDSFQSYLSEPTGFGTTTAASSSHSHPRATSEHGNFANTFLRESLGTMHAAQRQGTVPSSFATHFRQRQERKHDVPGRRYETGPENNARSGGSKEDARSESEEEVYYQDMPQQSQRRRSHRGSNSYGGLSAQQVFGGSSSYDMAQMMEQIRLSLKLEVDARAAIAERQLSALLQLCKATSEELDRLRIEVCATDRQLHTIDQVQAKMRQELTTQKDIGFHLQSMCGKDESWRVQADNQLLELRQLVAALREHGNSVQMQVQEKLSRQELLVQFNAAIEPIKAQFQATLQHQAQQLAEVTRTSSSSTLLLDALTQKVNRVQSDEIVELRNELQAVKSLVSRFSGLENRPRSTDEKAKGRKSRGGDSDEDTDDENFMKKQKKARDAIVKDVTSSARQELAQLVQSELEARLAAHTASIADLVKHEIHAVRSDFPSLARQCQEGLSALERRLTTHVDAQVKQTEQSVHSDLLSQLRDQKDRFDQQLIQGIAQQTSVSETRITSLQTCLQEMGKSVEADHRECKQSVERVAEDLRKTRHKLEEHLHRMGIEQRTKVTVWNDELSQKQREMERKMGDLSETTQKEVRQFVEVTQTKIREEMSRQSDDIAVKWKTLEEKLLKIEHSQAEATAAAVAASMEANKATETRVSVPVASSNETQTQSQLAAIDTTLQKMMMQLQLQQQQQQMQLALQSTVSAVYPPSIWSQSSAPPTPMAAASQTPRPARVEPATIETSAVVEKEGKEAALVSARIAKHTIEEKPLATAEKALSEPTPEELKLDEIISRVVTDELPRRVSKPEVKPEAPRPPLPPAPLQMKTEEPTSSTNQTSSSSSPAVDVLAKAQQVMASTAKGAVAEAEMAKLRVEARRKQELEARQQAVGSGSIGPPSILTRSVSASSLDPAVPSKTDVANTGIADGKGSPMLRTRSNSVNDISLSFLPPPEVPPPPASAARPPPIKIPEASSIAQSKPPPPPPSVPPAVPPSPLVPRPVSSALELKTPLPPSPSPPAQVVSPPAPALAEAKTPSPSETVPKPQAPPAAVAPSPSVSHVLCEQCRLPVRSDLLSDHMQRQCIKRTERCGLCENSFLWSERETHERDCPRRSTGLPSSPSLETPSSGSHTDLVGSKKCRHCSTDVPGGDLFEHELRCDQMLKQCPHCLRRQKMVELQEHIENCDCRLVPCPYDCGGKFLQRGIDKHLATRCPKRPAGASTTTATPTTPSATSTTSVAPSIAQPAVAVPINPAPTPSIISASGPPKAQEKAECKFCDEEFNTRELDAHENNCDWKPRRCQHCNMVIIARDLIRHESSCKTSTKNCPHCNESMPQAALTGHTSRCSKRPIKCIRCCQLFPADAIVAHSSNCKFLPSSASQPSVTAATPAQSITSGSATGPTTRPPSSIGQTSATTPLKIPPPPPYPPSTTTTTGATVAQSINRAPPPASSAPAKTTVSEEANVADRLARRNLALSQLTGQASPATAASIQREMSQTSTTATRVLEASGHPEVAEDDDEDEDDEEEEDDEDDDDQLTLAQVVAEWSVENVCLWLHEDVGVPEVVPRFQQRQCNGEMLLDLTESDLINDFGIKNRLHRERILSAIDAIKTSDDFSDEDEDDDDDLEDEEEEEEEEEHGTHAVTSASHSGSTRRPSLDESSFLHPRDLLRRNSLPSPQNSPLRASASSSSNSTLPSSSAMLRRINSALNVEFPSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMP5</accession>
    <name>A0A8K1CMP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMP5"/>
    <dbReference type="OrthoDB" id="263617at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="71"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="209"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="57479" checksum="C3012CD81C91C641" modified="2022-08-03" version="1">MRLEMETGDADVARIKSRHKPRHASNALVDYVEQSLAVRGRVEQEERHKPRRRRRKKPTKTPDPEALDTVKRVIVRNLVTPDELDDSDEYGDVVEDLRSEFERFGPFMAFDLDRSTGELVMAFESEEQADEVVKAKHGHVYGGKALIAEHAVAIPSLHGVDDSPTKTVTPTVSHNEPVESKQKKKRKSKIKSAVLARRQQHNVPLAPDTRLVVRDLVDPGEVEEEDEYEELVEELTSDFARFGRLESFIVIREPDDQALCSGLPVGSVVVHYEAFQAAQAAFAAYNGKTFGNRVVTSSWLPIPNNTLHVHGMVEPDEVVDEDEFEDVRDEVRAFFTKLEGVQDVELSQRTGDVVIHFIDPEYAMLAQEKLETIRYGGKDLIVKPELGSVSGQQDTPRMVKSNTAFGQLQSTQTEHMSSLIISLLQRLSSLQERAHIQNPLQDKRSRRLVLGLHEVRRGVISRKICLIIVGTDVEACQLLDETFGEILQLALKQDIPVICSLTRCAIDCYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMY6</accession>
    <name>A0A8K1CMY6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMY6"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14832">
        <property type="entry name" value="AP4_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000010">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="144" mass="16923" checksum="ECB75A6B821734B3" modified="2022-08-03" version="1">MIKFVLMVNKQGQTRLAQYYDFLSIQERVALEAEIIRKCLGRNENQCSFVEYRGYKVIYRRYASLFFIVGVKDDDSENELGILEFIHALVETMDKYFESVCELDIMFNLEKAHFILDEMVMNGYIVEANKISILKPIHLMEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN28</accession>
    <name>A0A8K1CN28_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN28"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19508">
        <property type="entry name" value="RecA-like_Pch2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000680">
        <property type="entry name" value="pachytene checkpoint protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23563">
        <property type="entry name" value="TRIP13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="172"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="448" mass="49848" checksum="1E40614BBAF85F1E" modified="2022-08-03" version="1">MEAMTDVRAAVDASAVKKRVHVEVCLKAASVAGYEEIRGVVCEYLQHNTSIFTKGTIHFNDVELLVQHVEHMHVTEIDSSDEEDAQNEGVPHWEAHVIVHVFKLSDEPPAEETAEDDDNVSTCQQLALPATMLDGLWESLIYDTTVKRNVLEYATTAMLFSDSKVNPHIISWNRVVLLHGPPGTGKTSLCKALAQKLSIRLADRFPNSYLLEINAHSLFSKWFSESGKLVMKLFRQIQELVEDEEALICVLIDEVESLTAARKAALSGSEPSDAIRVVNALLTQLDALKNHPNVLVLTTSNITEAIDVAFVDRADIKQYIGLPSPHARYEILRSCVEELCRVGLIQGSSQTLLTYRELQRKRASKKRVADQMASNGTFEGDEDLVVSSALLRVAESAEGFSGRSLRKLPFQAHAFFVQARTTTVIDFIQSLSRTVRHEIEQKQQLTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN37</accession>
    <name>A0A8K1CN37_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003904</name>
        <name evidence="4" type="ORF">Poli38472_003907</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN37"/>
    <dbReference type="OrthoDB" id="165008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="78140" checksum="199725F773CB03F0" modified="2022-08-03" version="1">MFDSISRVAAAAEHAENDKPTPVKVSLPPEHSKRDTKITWQRVLHLVHRVFVFAAAWWYIIISFQASYASMELLRGHDNSARSGTIFPFPVMTSLVGAGPIRTSSLVKTTFGDDMTPRDSSIFVVSDGQAVDACPLSPDNYLYTNEFMRAIFTTISRDTAYNITALDEATMELIAPIIDCTYVLQPNSGTTGGRLFYLARERANPDRVFLVVVSLIVQQYSISAQAETGPAAVGMVQVIYDMREPSVTNYYVVAKGFPVEEMEYRVYEYLNTTPDGQWTLRSIPSTKSEFAMVLITSIREGFYIKAPSEQSNINNQVWLAPSTPSEAVGIWHFVYTPVLRDSWAWVHGVQFIIGIRLLGNLVILCLTAYNNLRARKLWIGAAFVSISTSQVLNVVLVLVSWFMNEYWSLHEYSVTVGYAVIGLPDRLIHDTVMHADLLTLYFGACGLIGSVFRERIDPLLAMALFEIGYDRQTRINLLINSHHLHAKIQAFAYNFYMRGVLAPLNGQDKISPMVVQASHNMGKRDYDYVAVCLFPVFLNLVWVVAYAILRKIYRRIFPPKVLIQQNTTGTARSGNEESILAQKRVHTLFELATGAELENRYGLVSDYDTCIFIRGTKFASADGIYSNGFVIANKKYLVQASDIWTIVAMKLLRSRFTNVYVYEVNGTTVQPTALLVYPHTLTVRDLLNLNVSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN65</accession>
    <name>A0A8K1CN65_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_008317</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN65"/>
    <dbReference type="OrthoDB" id="157607at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF508">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="22"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW65675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="363" mass="41913" checksum="A82E03BAC451BE56" modified="2022-08-03" version="1">MPRDQAEAYFEPLGQCRDVDDFEKLNRIGEGTYGTVYRARDRRSQRIVALKRVILHNESSDGFPITALREIKLLKRLRHPNCVQLLDVVVGRKRSSVFLVFEYCEHDLAVLLRSHSGRRHPPFKESQLKRIMLSILQALDHLHRQNLLHRDIKLSNILYDRYGCVKLADFGLAREHTSDSQRPNTADAKDADAGLTPKVVTLWYRAPELLLGTENYSSAVDMWACGCIFAELLLQEPLLPGSSEMDQLDKIFKLLGRPTDHIWPGMSSLPHADKLSFDATRYSFNHLAKLLPDLSERGLDLLNRLLTYDPEERITAQEAMQHPYFREKPFPQEASMMPTFPSIHGDIKPTDDRHDHRDKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNN7</accession>
    <name>A0A8K1CNN7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNN7"/>
    <dbReference type="OrthoDB" id="289314at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="1">
        <location>
            <begin position="110"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="262" mass="29477" checksum="CC2B3FDED7CE174A" modified="2022-08-03" version="1">MVFTDFSFLQEQGNDPALVSVMEKYPPVSVLDTWANPANDERAAEDGQLVKAESDFQTFAVVTATFARQTSDNSPVPAPRRKTRMKSYSENGAALERMVQSKARPYSVGNMYELRRVSISGCTKNKNGIWMFKVDIGTDPFDSYAVRRRFSDFKELYEGLSEELEEEEELPELPHHGVYSVFQLYFSPEPALNQRAKKLEELLQFANNHPVLSLSAPFVKFIGKNPSSLELGYVSLSSYEAPTSDGLIQFPSARSRARCQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP29</accession>
    <name>A0A8K1CP29_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">V-type proton ATPase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP29"/>
    <dbReference type="OrthoDB" id="10261947at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10580:FF:000004">
        <property type="entry name" value="V-type proton ATPase subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="entry name" value="ATPase, V1 complex, subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005772">
        <property type="entry name" value="ATPase_V1-cplx_fsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01101">
        <property type="entry name" value="V_ATP_synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861:SF2">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015945">
        <property type="entry name" value="ATPase_V1_F_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="AtpF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="12643" checksum="8519C182ADBDDA3D" modified="2022-08-03" version="1">MSDGSKLVAVIGDEDTVTGFILAGVGHRTAEGTNFLVVKSSTPISAIEESFRKLSSRDDIAIILINQHVAEEIRHLLNTYDKTIPTVLEIPSKDSPYDPSKDYIMKRVTHMLGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPI0</accession>
    <name>A0A8K1CPI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_011007</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPI0"/>
    <dbReference type="OrthoDB" id="265776at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUSP" evidence="15">
        <location>
            <begin position="50"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="14">
        <location>
            <begin position="239"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="13">
        <location>
            <begin position="302"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW67387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="887" mass="99500" checksum="54F3229398B301EF" modified="2022-08-03" version="1">MGKGKKKQKAHKKQHKNPAASESNGAPANAAPTTPSVNAVGVEPRSNKLLDRTKQRAIIQRLMKQADEQGLQVGDKRFVIAAKWWERWCQYVGYDSDDSSSPAGTGLLTNASPSKINNLPLLQLPADKLDELMGAPLRPQLKESYHFALIPQEVWDALLCWYGGGPAIARFVVEVGDRSLGNTFKRVELYPELVEQEDDPMNGIDTAAASSTTANGPATEITKPPPRKLPVPSSIQKMCGACRTTTGSLKRCGNCQLIWYCGSACQTAHWKFHKSACRAAVSNEDKESAIQGSLEEERRGKMGLRNLGNTCFMNSALQCLSHVEVITKYFLSNKYIRDLNKDNPLGTGGSLALEFDALLKELWFGTSPSISPAGLKRAIGRFAPQFSGFQQHDSQELLAYLLDGLHEDLNRVKQKPYTEVKESDGKQDDAEVAQEAWKRHLLRNDSIFVDHVQGQFKSTVVCPICSKVSITFDPFNCVQLELPIQQNRRMEAIVVAKGKQMMRYWVEVPKKGNILSLKRAVSKLSGIPAHLMIATDIYQSTVYRVISDTERLAMLRDEDRILLYHVEPPTPPPSSDGSEPQPLYYGFLYHRLDTALKGDPLLFTFTAETTCEEMLETWSEMIAAHVAQTKGLTSKLSASLLATCTYLSNRDGAFMRSEAVPASKTSRFLDYATLNPDEGLEDLVYMSISWSPALLNSPGGPRPDVEHVADHESMREHAAHKGTRDGISLYDCFRNFTKPETLDQANLWYCSKCKEHRQARKTMEIWKLPDVLIVSLKRFEYRNEILRDKLDAFVDFPLEDLDMTSFCLEKTEDPERLRYDLFAVSNHYGSMGFGHYTAFARSWQNSDKYPGWYSFDDSQVSPAMPGQVKSNAAYILFYKRRQLTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPI8</accession>
    <name>A0A8K1CPI8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPI8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="134" mass="14985" checksum="5B856F9867B9D327" modified="2022-08-03" version="1">MMEAPTFMDAVETGMTVPPPYSGAQGTSASESEDDPMLVDEQAHKTESKRTYYARKDEIRKLKAELSALTERMEQIQQIKQQNDDALMQMSAMSAFNSPLSLQGMTTSESEDDPMGMEEDTSKKKTKPTYTRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPL3</accession>
    <name>A0A8K1CPL3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPL3"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="42"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="362"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW67165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="487" mass="52023" checksum="496978D812611ABF" modified="2022-08-03" version="1">MAEHIPLRRTRRVPLEALRRRLEGQASSNGVVPLENYSGVVYSAEMTIGNGTFRVQVDTGSSDLWLSCYYVDRSRCQLTCPSSAVVITYGSGDVCVVREYADVQLGSIAIKDYAVGVAMGANVLPNSDSILLGDVEGLLGLAYPSLVTIPSPVGTFTDFVKSFSTYLTAEDGSDGSFLLLNAVDEDFIKENKLTGLSVPLKKAEHWTLGLTSFQIGDETAVAPCSASGMSSGSCNAIIDSGTSLLIMPADLYQSFAETYLLPNGCFTSEEVASGQVYICDSSINLPRLGFTFSNASFYLEKADYIIEASPTKIIVELQAASTINEAAAQMWVFGDTFLKRFYTNFEVNQGVTFYCNEGKTCATSGSSVTSSTTSSSTTDTSTPSTAPGSTLLDGTFSPSTIGGTSSGDDKSSGLSSLERTLIIVAAVLGGLLLILLFFMLRRWLAVRHQRKAQQQRAMAYNGGETVASTGDAYNIVMSPMAHTNNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPP4</accession>
    <name>A0A8K1CPP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPP4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031974">
        <property type="entry name" value="PDCD7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16021">
        <property type="entry name" value="PDCD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="42469" checksum="1CC83A4D9A076343" modified="2022-08-03" version="1">MRHHAHPPMPRYPPPPRLAHPPPPTAFYAARPRPRPLPPVDPEEQWLAAFKRQHLSDPEPVVTTLTGPPLQAVRLHLTEIESLVDDLEHNATELLTHERRLDELLTSEDDDENSLEVSRLRLQIERERSRCAQIQAAITAKCSPGPLGLSKEMAEAITAFARRAQKKKRWRQRAKARLQAARAVRRGLEEGRTDSREQSIQSPSIEEAATPRTSNDISGSTQAAEATSAASSSEEKVTAKKLLLAVELLKKRRGDSLTAEEQHAIDTAQREAEARLHRRKRQKKPRSRSPKAFSEEINSEKTTQTQDTTSTHAQTVSRPLLQDPACPDMEALVATRRHWDRYIVHPAVQGASSIPPHFVIPPVHPSDMWSVYLTTETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPR0</accession>
    <name>A0A8K1CPR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPR0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="23965" checksum="5B9303D1F1B632FE" modified="2022-08-03" version="1">MGLEEFQSHYMFTPYFKLKITETQTEKALDWKKTWRHLFAYEGQDASFRANHKQILKQFEEYQLELTTFPGIDIELDVKPPRKLTPEKQLEYLKALTTVVSEAVSHSAKAEKDHPMRPRFNIDAIYLDIGDLHIRHDIVQQLQELLALNVTIKKLTIQPTVTPEKSGPQLWRSAWAALLFTICGHPGASVKPGKPIEHLHLVQPSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQQ9</accession>
    <name>A0A8K1CQQ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQQ9"/>
    <dbReference type="OrthoDB" id="67991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47175" checksum="8EB9E564E9BDDEB0" modified="2022-08-03" version="1">MLAAFGLDIYRKAPGGKAHCTIPTDRLAVLMLDDCQRQFKNVPFSVALLKNSASLLPQHVRIVLSATHLLEDANPASPVEFGNVVARLTLEEFLISDDESKAFLEKENGLHKNMQYSTLMEILIRECKGHIGALRCAIDSLSYHFSKSSPTLAEVLQFYFSSTFLGYMSRCYGSKHTSPTIPALQQFLIKCLVRDPTAGPIYLQQLSQEDESYLKRLTKAGIVTTDRGGFVRFMTPMSERYYTQWLFPYRAAGNPTSLQELVRKALSSMSASMLRQSVASARDLPKEATFQHLFLTGLAHHTSASCFICHELSKVFPAEPNELTNGQMDFHLNGDLRWGIELLVDGKGIGEHMRRFAPGGKYAALGAAQYVVVDLRGNESGRVTDVVREEHRISVFYKLGDFSSCRCIFGMEEDPRPIVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR08</accession>
    <name>A0A8K1CR08_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR08"/>
    <dbReference type="OrthoDB" id="157554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="37479" checksum="7D3D3DFFA99E3262" modified="2022-08-03" version="1">MNATSTWEQDAAPGGYRSTYYARKNEITTLEAEADMLTQQIKQIKAEQGVMAAALHDNTLLRPSLQVNAWALAEAQSVLTNRMAAQGVHPLATYIHLTADPAQRQYTLQSLRDQKLRDATEFLIRRTRFVDLCRSHRQVDTSEMPNGDVEVEQFVVIPFPGVSSVKIVYEGLGEALSNQQFVVWEQLGATSVSDFEGIADKSIRLLRHVTKVAPGVEMEKNGVSFRQYYEKSDLVDGPYGLTVMDFVDQDELHPYQPTSRVRLDVTSALMVCHSGDASVSFVRWTRSCIHRPHESINPHVVESLRDFIPRWAEATHKAIREHVALTQRSRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSI3</accession>
    <name>A0A8K1CSI3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007597</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="737"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="792"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="887"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="967"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="106"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="427"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="751"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1073"/>
            <end position="1307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1321" mass="146559" checksum="28545625DB38BB6B" modified="2022-08-03" version="1">MDKWLIRAFATFDARDMTRYATFATASRDGITSHPYETASWLSRAMLSWVTPLMTLGNQKQLDSDDIWPMQPSQQAGTLAKTFSKDYDASKSLVRAFLGSFGGRFVLTGLASVVAMVGILVGPMVLNKVVTELTMETYDVRELMTWIIGLFATQVVQALVETHTNLGLEMTSIQLTAALKNLIFAKSLRLDAGSRREKTAAENTNLYTMDCEFVTDCATFFHQVWLLPLLISIATVMLYRLLGVASLAGLAVIAVALFANHFIASHIMTKYSEFVRLKDARMQALMEVFKSITIVKFNAWENKFLERIGEARVKELVTVWSVLKLTAASVVILWGLPVLVSVATFSVYAGIMHEALTPATVFTSIALFQLIQMPLREVANIVAAISKAYVAQKRIAAFLEMPEIGTDNVHSIQHPDANQFIKQNIIVAIQNATFAWDNDTPILKNINLNVHAGDFLVIHGPVGCGKSSLCAALLGDMNKTSGGVYVGGSVAYCSQQAWIQHMTVRDNILFGRPYDRKKYEKVLEACALTKDLQSLPAGDRTEIGERGVNLSGGQKARVALARACYSDASVFILDAPLSAVDAIVQNEIFEKCLLGLLRHRTIILVTHNPEIIASEHVTSAVTLNDKGELVETRKVKHPSRPQYDSAITPLALLAYTRPSYDDEIHHQHEEHHHLAESDLNVLDMAKEVTTPSSRRGVEVNSRRPSFVEADEADEADETHVLVQAEERSQGRVGLHVFVSYYHAIGGFPVLFIVITSQVLWQVLQVSSDLWLSQWTTRSSSPEGDTMSQSSRIGIYAALGLSSALMVVVRMLTLSWFGIGAAKRLFDRMVYSLMHAPMKFFDANPIGRIIARFSNDVTDVDMMVPLVFGSFFANLLVLSFTMGTTAVIIQWKGLLLIPVMIIYVQVGRFYLEPAREIKRVERTTSAPVLSHLSECVDGGAVIRAFGTDQVLRFHFANDSKLDSANKVVYARLCVAMWFSLRIQLLGSLLAFISSYSLVLLHKELSPAIVGLAFSYVLKFSYSMERIVKTWSSVETTMVSPERMQQYIDIEQEAPHKIPTFDPPASTAWPSAGAIQFENVSFRYKDADQLVLKNLSFFIQGGEKIGIVGRTGAGKSSLTMALFRINELAGGSVLIDDVDVGKIGLKTLREKLSIIPQNPVLFKGPLRRYLDPFDEYTDDALWNALRRVGLIDRITSEDDKLECMVEENGENFSVGERQMLCMCRALLRESRIVIFDEATAAIDHETDQKLQRVIREAFVGSTVLTIAHRLDTILDADRILVLDGGEVVSFACPSELVSAGSGHFYDLMREGGYLDKFLGNTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTI0</accession>
    <name>A0A8K1CTI0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTI0"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052079">
        <property type="entry name" value="E3_ligase/Copine_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45751">
        <property type="entry name" value="COPINE FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45751:SF11">
        <property type="entry name" value="COPINE FAMILY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="40"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="29927" checksum="FF5FD0DF618BF758" modified="2022-08-03" version="1">MGCAPSSELAKRLDLNKAIPDQYETFEQLQDELRRQGLESSNLILGVDYTKSNTWTGKTSFQGRCLHEIDPSGFLMNPYQSVISIIGRTLEPFDDDNLIPTYGFGDASTSDKAVFPFKRDGDPCQGFDEVLRRYSEITPQLVLAGPTNFAPIIHEAIRLVKTTNSYHILVIIADGQVTNEKDTSAAIVEASKYALSIIVVGVGDGPWDLMEHYDDSLPARRFDNFQFVDFNKVMKLNQIKPDVGFATAAMMEIPEQFKIIRSLGYLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUA8</accession>
    <name>A0A8K1CUA8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUA8"/>
    <dbReference type="OrthoDB" id="38351at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="401"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="564"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="597"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="670" mass="72756" checksum="8F8DEF85E810A9F1" modified="2022-08-03" version="1">MFGGLFGRSNEEKLRKAAKKGELSKVRKLLAKGVDVNASDGDVGTALHWASRDGHSDIVRELLGQEACNVNAVEDGWTALHWASSRGHIKVVHLLLGHKTCDVNALTLDRKTALHLASEHGRLDVVRALLSQEACDVNASDAYGRTALHWASWDGHLDVVRVLLDVKACDLNAQDKDEETALHFACWLAYHEVVRELLARGLNPSLLNQSGDTPLATCLQLKGLGSQTRKDQIFWYTLKTAHALLSSGATHEGPEEILPSVEDKYKDLAATVVFCVRHWTDEQQRKQSSLTAVPFERMTESDTIELLMEAMSKGDLGRVDDILSHKDIDVHAVMNRCYLAHMAIRFDPPDMLAVVLAHGADPTLIDEFGLTALHEAADVGCFESAMLLLSHGVDPNVRGGSGKTALHEAVVCENAVSAQFLLALGVDPNATDDSKETALHYATTNRHPNVMEVLIAGGADVNAANKDGDTALHLSCTFGHADRMEVLLRNGADMNIVNNNGVSVVCQARGRLYPLELLVKNGADINAVDCYGETVLTQAGVDGDLEIVEMLLNYDFDALVLNREGLTALHELSWRGHVEAVRAMLTRGVSPNLVDKWGQTPLHVAAEFGEIEVMRLLIQYGINTTAVSMYGTTALDVAIAAMSSSPEAIELLQAHDIDLRAIGDVGDTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUC2</accession>
    <name>A0A8K1CUC2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005876</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUC2"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11709">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045129">
        <property type="entry name" value="RNF123/RKP/RSPRY1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025086">
        <property type="entry name" value="SDE2/SF3A3_SAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363:SF5">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363">
        <property type="entry name" value="RING FINGER AND SRY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13297">
        <property type="entry name" value="SDE2_2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="175"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="7">
        <location>
            <begin position="262"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="175"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="588" mass="65387" checksum="E70909AD934D9693" modified="2022-08-03" version="1">MMTDDLEFLVHFNRALCLSLPASEASVEGIKAHLQQREGVPAERLELLVDGRRLADDADVPCMPTMLRVRMTDGLLGGKGGFGAMLRSMGKGSSGKATTNFGACRDLNGRRLRHVNQEIAMQKWREESELREQRKKAGITEREIMDEDTPSGIAGWYLATPSWAEGVKVSYMKRRRNTVLCKNWVDARSNGCTAPPDAPRWWGCPRGRDCDFAHGEEELRGAGLTDLKKQKKDEQYQKQQQKFDSYVNYEKEIPDDIHDAVRQGMRKRNAKNKAVGASAIDEELVLPPDALRPHVRSSVEIPDGWLKPVQDSLSTTFKFGLCELRGSGNFGTATMDECRLTSGKWYYEVKLITDGVIQLGWADHTFVANSETGDGVGDHARSWAYDGCRQLKWNAGKEEEYGVAWESGDIIGCLLDVDAGSVQFSRNGELMATAFSGMKLLDGAAKGFFPVISMEKAEIVLVNVGAQPLLHPVDGYRPIVEALDPPAPTPASEVLAEMKPLENNETADVTEAEAKKGEELVELIDLDKYKSAAELEKLGLEGLKQQLNHRKLKCGGTLQQRAERLFSVRGKTWDEIDPKIKDFKALRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBK2</accession>
    <name>A0A8K1FBK2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBK2"/>
    <dbReference type="OrthoDB" id="110562at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="642" mass="71566" checksum="CA131303B1DA6A3C" modified="2022-08-03" version="1">MARGNVSNASTSGERMTRRRAREAEPAAPSERAVSTASPARKRGRNTSNSRSKREESSEDDADDDAELLASVSKETRKMTSKRQRGKSAILAEFSSLDALLSNDFEEKQRKQRREDKLKQLREESKTIGKRGGIDTSSPLARLMSEMENNMSSLSADNHLFTDDLPRSQEKFGFVFTPITEPLPYTPFKATAAELKSELGLVYKTLQSKNEDELSALLWSKAILLRCLLTGKPPSKAKVTSTSPVQPVVVPARIGSWLFMTMSTHSNSHIVKGCLSNLFVLVASSGHLVTTDLNAGLACASFCHSPENLRGIIGEAMPDLQMEWRPTVYDFLNAFRRFGFQDSKRSMSAKSKITPTNASSSKRSSLGSNKAPVPFPTLNMRYVLVFLILSIRANLLRLDGYDAFSFTMFFLRMQFEHNMHPEIVQLASICIEELLEVFPTLEWRKEWAPSLVLRIAGASEGLFDSASGWLMVARRLPRTARGTQLTTGLAVYVLQHRIDKSSEAESNSERPLKFPIQSGLVLDIVAGIVEDMTVKYTEKKNRSSPGARAQQPPYDLLCKKVALMDLALQAFLNVLTQKEMSILLKKLDDLTGSHKSTMSAKWHELKTLVGLMHRKYSLENLRIGRDAEPSAMTVLFVDDAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBR4</accession>
    <name>A0A8K1FBR4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBR4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="25682" checksum="C404606AABAB96D1" modified="2022-08-03" version="1">MSTSGGAKAKTRAPQHYSDEVVLTCAVLGTSTVLRVVVDPSIIVHELMVKLYDREEIRAHCSAAKELALFLATSLNATRGETDKLSPGERIQERFPQGYPPVDVVAILVKLPTKPSSPGEPDSVEHDTHDSTPFQLETGDEEPDGDDRHGSRTRMLLVTGAVCCVIGLHVTIWTHYTAADIERAFILIGMSEANLEGAVCTIIKILEPPTSTIDAVKELVAFAFSTLRTALLVYDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC59</accession>
    <name>A0A8K1FC59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC59"/>
    <dbReference type="OrthoDB" id="278280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681:SF0">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681">
        <property type="entry name" value="ZINC FINGER-CONTAINING PROTEIN P48ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="391"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="481"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="575" mass="64386" checksum="D16B381FBE5DA9C5" modified="2022-08-03" version="1">MMIYGEHSFTIYRIDGAPSVSVQPGRNVATESEYAVAITIAGVTQSTPFGSPLSILQTLKYKLVGIASDSTVLIEVMRLGDTDGSIAAKAVPLEWFKSRRSSFIRRKVIVLEFPKVAGITKMTEFGPAASIIEPLEFELVDVSNSSQLLVEVLRKGDLERNFASKGNPLTWFEDQRATMFHKNVIAMDLPKGICVHLNCKWKLSQVPIRRPSQRESSVVLRIATMPPKSKPQASKKAEQKRKEQILEDKTFGLKNKNKSSKVQKYVAEVTNQVKGSKSRADRLKEEEQKKKKTAKEQADALKSLFAAAITQPKVPPGVDPKSILCEFFKQGVCTKGARCKFSHDLNVGKKAAKIDLYSDNREDKSKDLMESWDQSKLEQVVAQKHGQKVATTTDIVCKHFLDAIEKSLYGWFWVCPNGGTSCKYRHALPPGYVFKSKKEREAEKEKKVDEISIEEIIEEQRAKLGPHGGTPVTAETLAAYKKEKMEKKRVEEEKKRKEEAKKAGGRGPMSGRALFTYDPTLFRDDADADDDEYSVHSLNEEDDDDEEKPSVDQAAAVLDKSLYLQDADDLDSLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD10</accession>
    <name>A0A8K1FD10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="4">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD10"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000035">
        <property type="entry name" value="Putative lipoyltransferase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010925">
        <property type="entry name" value="PRK14345.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="12">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="172"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="11">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="239" mass="26708" checksum="F336F1AA43860ADB" modified="2022-08-03" version="1">MSSTATDAARKCVAYRLGTVEYETAWNWQKELIQQRITASREGCAIDHDVVLLLEHPTVYTLGRGATLDNVKFDPERESLKLIRVDRGGEVTYHGPGQLVVYPILDLNYHKKDLHWYLRQVEEVVIQTLARFDINGERVDGLTGVWVKEDGDELKKIAAVGTHASRWITMHGFAINTTTDLTAFDRIIPCGIDDRAVTSIERIRPEVTLTQVEDAAIEAIKQVFGVDVAAVQGSTPFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD20</accession>
    <name>A0A8K1FD20_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysosomal thioesterase PPT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD20"/>
    <dbReference type="OrthoDB" id="155976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426920" description="Lysosomal thioesterase PPT2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42280" checksum="A792BF96FD06D91F" modified="2022-08-03" version="1">MARRLLALVVALCSFSAVSAGPHHHRLRELVRVQGHKAVDEHAPALTPKPLPVFFFHGVTANASSGYNYQANLTAEGRVFVALNFCPSLCSVSALPGQVQAAITAVRTRVASDAAFAKGYVFIGHSQGAAIARAVIEEMDDHNVKMFISLAGPQTGVFYGPQPSDIIPRMAFTMRIGPQMIPSFDFSKYSGADYAAGKFQSDFNALVLGNPLLQQQLSVVNLGRSPVKKAWRAVNTFLPVINNVNPCGKGDKQCMADKTRRRRNFLKLKSAHFFGSPADDVVAPWQSSILGQFNDVVTSEDILLNFPLFRVIDMKLTDEYEYDTYGLRSLDVRGGLFLYAVPNVGHSCWVADSKPLGATEICRFQPVYENYIYPLLHKQGWGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDV5</accession>
    <name>A0A8K1FDV5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDV5"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911:SF4">
        <property type="entry name" value="MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="145"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="353"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="323"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="881" mass="97404" checksum="71F9A424A0404C30" modified="2022-08-03" version="1">MSSSAPSSLVVGVVAARNLLAEDINGFSDPFVQILLLDHRGNPLPTAPIHKTSIQKKTLNPTWNETFVLGQDGLDLRVVTTLRFLVYDYDGFKRDDTLGVVDVPMDLLLTDEIIDKTSDTWYMVKKHEGEMTKDATGELQLTFTRPSVSKAATTASPAAAAAEPNLLYVTIDSGRDLLAMDKGQSSDPFVKLSLVGQKFHTATIEKTLKPHWDERFAFLLSDAHTTLELLAEDEDRTVNDFLGRAQIVLADVLVNGPHVEHKVMVKLLDKKLREDKDRGSLQLRLLWTYDENAESITTSMKKERKKTMQDGLMNQLKSSLHLGGGPPGAPIAVSSAHDEGHDYGQPWEDDEDDDGMLLQDESDGESEAGAADSLRFLVVTIHRLEELPPLDALTFDKEKHKPIAPGGGIDAYVAAWQSDRPEDFIRTRIHTRKGRREELSTSFHESLMLPLSAPTAGAKTNVTLAVMDWDQIGGDEVVSHIELQDVEQLVAQRGKQPFWWNMYGAPLVGLKNKEAVAKMNEDTLAGSTYRGRVLLTVKFQQKPKATYENKHQKRAAKKLPRSLFPLSQVYRLRAHFLSAIGMPVPHGKYYLSLSCGLNEITSSHKGAINHAIEWNETEESDRMLFPVDVTQIPDILLCLCTGEWEKRVIVGYKRFSAAELLKKEFNDTVGEWVTLTADPTTEAVDCDEFPGKVLVRLGFGTLESANAQVWDQKALIDQVSRRVPYQVRVRVQAIQAESGETLPSKFNLTVQCWDQEVQKNGVELTSTSKTPTTFCLDTNLPHLSVASQVLIHVKDATSKSSKLLGTAGIALGIAEDKANALVTLCTAEQLKTDKRLQLPVAGGLSLVTPDGSVTRVQVHASVELIRKTFPDEVLPSAEATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE20</accession>
    <name>A0A8K1FE20_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE20"/>
    <dbReference type="OrthoDB" id="119374at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="114" mass="12995" checksum="AD9B00B0AE68EFDC" modified="2022-08-03" version="1">MQVEGSIPSSMDGNRLLDITAKSSAVYAKFGLDEPPTKDSNMPRRKKLAFFLEMLQANDATSDENKTLPLGEKLFLNRRYNNTYQHAMEYLTQNELYELSAHAKGPCEYLKQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEN0</accession>
    <name>A0A8K1FEN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEN0"/>
    <dbReference type="OrthoDB" id="72033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22936">
        <property type="entry name" value="shulin_C20orf194-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057478">
        <property type="entry name" value="DAAF9_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056498">
        <property type="entry name" value="DAAF9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040342">
        <property type="entry name" value="DNAAF9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33664:SF1">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33664">
        <property type="entry name" value="RCG26366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25204">
        <property type="entry name" value="DAAF9_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23281">
        <property type="entry name" value="DAAF9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAAF9 N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DAAF9" evidence="3">
        <location>
            <begin position="801"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1235"/>
            <end position="1262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1271" mass="141818" checksum="0BFFAD5BB915C808" modified="2022-08-03" version="1">MAWRDIEFTGIDSVERVRRLQAFCADPGASDGSTGDIDGILIIGGVDSFHSRLSQALLKYLFLGSSGQELLGEQVISQQHDRLEEVVLMLTRRRVSIFYSSESEAAVKILPVISQWRNVTEYVIHDGMDPDDQENRKIHAFKQMVSGTKRIGIPYGLDENGKDLQDNMIPEKWPLVQSFGLEDGANGRGFFTMNHFVVNISRLVQQELSKLDDFCARRIVQQVEPLLSHHYNQFLAKLDHAETPKARCSKSESEMAEDLLSFYEFGTTQYEARGLQEAPHRGCRVLFGKRTASITTKTSSNVFLRDAGGVSGRPATHFLVQTEDPFSGVRFIRTYFLATGKLARQVVDEDALVHPDSDHLGKAAHDKDEGTTDTSFLIELYVLLLRGFRVAVDALAQECHEREVDSLQACLNTIKREAIKAMCEYSRSASRVIEENALPMDFLDEHLVIHAEPLDGCGQEARFPAQRWNLLFLSLEIQNVMSRLGSASSLGSVIVGDTVLFQSLSSCSSKTKSVVFNTTASFPYLRSWIQSGLEAERASALLTVLQSNFMLQCSALQLGRPLAPLDASLDDDTSIDPTNAATSIAPSTATGPITSLGLSKAALLVECLDLPILNGSMQLFSSGFCFRSQQVNPLVISFARHVSCFRILSTPFEELVLLQLDLKLDHATQQTPLAEVMPFKTQSRCIAFPLLAGTRFQEEIVRALATWKDAAEDLSIPFYRPHEAAMYDGMTPRDGETRAAEVAPIMVRTCEDLVRRQSQQNAATTKIAEVFFPRWFIPKESNPITTLPRPKQDRSKMCVPITITLGIPGSNAQAIGAMICSLSGADNDWHHVVVDCREADIKDAARSTDSNEQWLYSHVQTELNRTLARIVNERSENHPRVMLSVTGYVDPITVAAAIKAGSVSWAMPSKISAVISCVSALNAYLPDSLEAQNPLPKLFDQFTSGFVTHIILTHVSNVSSSYLGRLRYHMDQVNPFADIQVLPKDVFEGQMTSFLATDRFDSTYYKAYRDLHYPHWALKENRLNYVAGFDSMLIPESVRFEIAPGTEKSRFIQLLGAPLTPFAVMTKSIDKIHPMDRPLDRQSCKAGKGVQTADNSKEEIETEYGICWCIDATVTFSSEPETVYQYISTGTYAHMRVVSKSTSNNAKVTAEVPLEVKITGQKLNASKLNKLILGCYAKMDGAVQPMRTKKAFTMEEKREIQKKHMMDPLPDGFFFDGITYIDTFGGRHEFHPQINEFIEEHVRSLNEEAEKNNAKVEENRKSQVTFVKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEX2</accession>
    <name>A0A8K1FEX2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEX2"/>
    <dbReference type="OrthoDB" id="156249at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="47129" checksum="456C33549A61895F" modified="2022-08-03" version="1">MEDPTPIWLNDASLHAMEALSQPNMPRGGMETSVVTPPPCDRASVSTGKASTDAESSSDSTSSPSKAAKPMKNASRDRVKAETEELRVQVEALERQKHVLDEKKRSQLHITEKNELWAVIAHMQRDQRVKAEEENRWLKEALDQQLRIGRHMQHAAMQSGAKSNPYTTQSIRDLLVTPWSWTEDTKNVVRAYVVNEIDEYFSQVDSVFWWVTQGDQFERSVVGVARDNTGVEHSYVEARDSRWIPFEFSQVSRALWEVLLIQLRPEHKFFEWDCVGPDHVVLRFKSLTRKRELDGLTVATIMIRKFMENNRLVIVWKCLCTATEDQVSILDRAFGETNGWVSVERARENATESSRISICSKHYPLWKSNPGGTIKLRMEHFPDLVLSPMQEDIATIVEAIEGRLLDDALALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF07</accession>
    <name>A0A8K1FF07_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013588</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024372">
        <property type="entry name" value="Ecm29_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055443">
        <property type="entry name" value="HEAT_ECM29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF19">
        <property type="entry name" value="PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13001">
        <property type="entry name" value="ECM29_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24492">
        <property type="entry name" value="HEAT_ECM29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome component Ecm29 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome adapter and scaffold protein ECM29 HEAT-repeat" evidence="7">
        <location>
            <begin position="1325"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1025"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1031"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1041"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1797" mass="197390" checksum="46D5D975D1DFFC1B" modified="2022-08-03" version="1">MDGSDVKKEIEALERVLFRLASVDDERLLVVLDALLPKLLTLFPRALNTPLEQQLKDKVLEVIAHVKTRLSAITSPKLPLPALAALLEDSSHSVFTHNFAFLFIEMGFASASREEQTATLAQLVGALDRASTAQQETFFRCLISALPVTDASAIIKSEDAPGSVVVFDFLLDLVLYQPSSPGATSTTTYGLMPPRIERLQRVKINELKREALYDRQLLALQFIKQLPHASSTTLLHYVAGIASYHHVIKSYCEDQVHRVLKEDTETIENSRLCRELLCLVLGSQTAQTAGAFQVTRDTCLLSNRIRLADPSLLQAITVLSQSKAGTNVVPLLLQTICHLMFGTEPSRPLNIANRVKIAGANLCAWTFLHCELQFLTGLFGPVLQPTLLRTLMDPNADMDAANATFWREFRQGVYDSLAMLASRAPTMIASSEQAFQVLIVRCLVEEQQRMGANALKAFGAMREAYGSCAERAVLAKLRSELIGLVNGIKIYDPSKHYERVRAAVAEWALVLIERGQGDGDDIELRFALLKMSADKDEAVRLAAQCALYAQPLPSVRVLAERLRTIFSSKDLKNCVEPRVAEQCLTFCDRVITTQSKGVDPLPDHHELMAYFVETLVQQSTKTDSAITKDTQRLCETLASILTRKPSSIVVTLIHGRAHALANVAQISTNRVFLQNVSQLVRWSFHGGDQLSSDFVNVIESLSSTLSSASSPGNELCAALYVIGATLSIASENAVATSLSNEDKSVISHALSLISGVLKSTVVSTSHFAGIPRGEDAQNALLDRLRSAMDSVALAHEWIGCTSNPDRSLSTCLAQYLAIVEWKLSAIGSDGNLKQKLTSIRSVALENIGVIVQQSATSSEQELRSSVLEAVLKLGQEASAELQFTVATTLLGFGSTQDTAISLLNRIVDEHSTSRFPSVRRSSTIWLLSLCAAGLAASDVDQSVGTNAAWAQTFSSEVCARTIIAIHEHFVTMLNDTDAVAKESAVKGLAYLRLRAPTTDLGDEFSDSLFRRLRCFRAFAAQPVAPSRGQDASDDVDDDEASPTAQASASQESSASTTIARDTVENAAYREVSNVAADIGDPELMYSLLYLSTMDSVWGALKAQLMNQGATTNLFQTGFSFITVDEAFHQSIIEQANNQWMTEDFVHRRKLVPWLFLLKHHANPKVTEVMTNLWNVMKGAVSSATQQEKTLVKQHWNEILQFVLKRLELSRNFKYREAACGALLELLNGASADDLRSEFVRLWKLTARSVDDVMEAVSVAGLKLFRALGELSLRVASNDNECRFALLEYLISEGMVSKNVMCRALSIDLLLRLMKELPASAVYDRLAALMLKLLEYLSSLEMPELQYAQFHVDKKDQLERLRVSLSQSGPVGQLLEHCTVQLKALAVDGHPSCLQIVEDLCRGLSHLLKFGVGLNTRVGTANFVATLAAEVPFELRKSNGAEQLMTRALIPYVGDRSATENDLYGDDGTNGSGLSDALVLQSYCRATAYLSPLVSPSVVKAYVRDGIFAFHSRRSATTSSPSEDLDVNNDTYSSRFLLVSALATKELVAKCPPLQNPNDVVTPDERNEWYSSDVFPAAFIGQFAGAETLRTTWTAVMEELPPTILYADPSLTALTTAIGRLVRHPAWDTRRQAIKALQSLFAGSSVYRTRITASQLDQIWQNLLQAVPGRLWRGRGVLLEALVAVALVRREGWTVLVSLLLEEADRAMKNRDTEYLESGLVALSTLAGGMPATEDSLRLHVLDELRTRYIKKIAEQHREIFELLEATERLVVASPFRIDCEASPPAFVVDTALTNHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF56</accession>
    <name>A0A8K1FF56_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF56"/>
    <dbReference type="OrthoDB" id="77741at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="606" mass="69110" checksum="CB1C37F9B48E7E57" modified="2022-08-03" version="1">MTSSQRRFRSKNGTKVEHLWRLACDKYESILCRIHPLRVHIYETREALLEDRGLIHIDSPIVELGVTASRALAFVVLPDVEKLQRPLKRRKTVWKETMSLPDRSDMVMINEATGKASSDYMKIRAAVLDGFGAHRGQHDLILYLREAVHWVFAYLQEDVLLTGDIGYISGPAGTGKSCAAVAFAVGRVNQSEWVVTWIHLVLGGFPIAVRLESNVKKTLEVRFDEYLRLDDILELGFEGVGSTKKHLLFVDNVTETNDTLMRACVGWARNDKNRRLVFVSPTVNKNYRKMLDQNHVQCSLHRLTWWRLDDYMSALQNQALLQHVLPQLDASEEPLPPMSALEPSRIEALARSKLYFTGGNVRYMFDNTTMELVEDLLDTLGRRGESAVVSFVKEGPLEVLCPFVPVLIAIAWNVAAFSVSWNFMALDSHWVYAKAPLMLETFFFSRLKRSSGVRLYERRGDEWCELQWLTTPVNILGRDQMEGYLEKDEPLWIKLLQLNRGSFDAVYLDRGRGLVRLVQIAGGHENVLSLEYFVRFVHRVAASWTWTAVVSVEVVVVVERSGLSDFEFASVSGGELMQVFPGWELNEGATNVRRVGIDSPKKWRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF60</accession>
    <name>A0A8K1FF60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CSC1/OSCA1-like 7TM region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="192629at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF135">
        <property type="entry name" value="CSC1_OSCA1-LIKE 7TM REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="756"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="800"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="841"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="911"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="964"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1034"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="426"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1361" mass="151596" checksum="B03008E57D19CF5F" modified="2022-08-03" version="1">MDDDELIDATLGTLPTLIVPDDPVNGAIEKPKTPPPSAPPSARAATAREEQHAEEERKEPDAVEVPVEVVPVVVDTAPPVTAQEPLPPITAVEVEQSINSKDYRGMAKRAIGLAKMDRLAGGNKSVFDAEMSDIGALGIGMQLYFMLTKYLAITFLIMGIVALPTIVLNKYGNGVTDSMVDPLELAYASLGNEGVHPEVKADSSLCLPKGDIDCNWTTVNTPFTSDPVTVSWIITISDVVYSTAFFVFYLVYRYRARKAIDTHMNENLTPAKYAVFVRGLPPDATEVEILQHFNQLYDLTKDEEASPLWCGCCWGRRRKVKTSFSRNAVNRNTVKNIDHLACTIQPKKDLYVDTWIAEISIGHPTGGLLRTFLSMEALTRSIAETQELVRILEKEKEEASTFSGGGKNKCFKPSDEKLLQASVKKLALLNERLAKKTSKIKALKQGQKRTESIQAIENPTNKKNLKASMKAAKRAAKKAAEATQHGFNWNACECAFVVFNNLESRRRCLQDYRRSGNWLARRYQPKVLRFRDGKYPLIVRPAPEPSNILWENLEVTDRGRFYRRSFTNFVTFLLLLFSAGIISAAQSTQQDMKKKMVTPDFCDSTLPLVYYGNLSYLSRTDLTWQLAWDANATCTPGTKNETRYHIAYNNSIVNDLHITTPAYWPANGGERTRCVDPCISETSTRTCHSMACFDQDIVDEGETCETYPEANILYCFCKDALTESIDQKGFYEGPKDLWSRYVPCRNFIRDYLIRNAFLYLAAGIVVIVNMLLKAILRAFATFEAHSSESAKASAIAIKMFGAQFLNTAIIVLIVNAAMNLNGLPLLKDLFKGKYKDFEREWYPTVGMGITMTMLINAFVPQIVLFVQMFLVAPVQRCLKRRSIRTQDQMNKLYAGPTFDISIRYPMVLNSVFVTMVFCGGSPILLFIASLTAAGTFWFDKLSVIHLYSVKTAYDEELGETALSVLPWTLALHLAFSTWMYGNTDLMKSRTINLDTMFRLLNIQVVEANGTAVSPTDLYNEFITETSKIKIVGDVVVRIVHSNVLVVFLLFTALVLWLLLSTVFTRLLLPILTRTFGVILQPIGRKIKQAWARRAARKKATAKVHAENKISPPKSTQVTTPAPSPPPQAEASNDTTNVAIPVDTTPVKDDAPEAQPPEGLSSLPIPPLSPKGKQKTLVSMLSPRSARVELILPEYTDYFRKTVPRRYNPDKQLGFEKNSEGQLIRVWQEETIQHGLKRLKGEHMRTWEAMQAPVKSYAIEANSKYKLAVMEIMAAAERLRVAAEEALAAPPATTPTINPTEEKILDVDAAIAATEPISVAVEQPLEAPADVAEPTDELVLAAPTDMDGGHQDDPELQVSFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF81</accession>
    <name>A0A8K1FF81_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">60S acidic ribosomal protein P2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF81"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478957" description="60S acidic ribosomal protein P2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="11159" checksum="149FF747FE695A4C" modified="2022-08-03" version="1">MRYIAAYLLAVLGGNAAPSADDVTQILSSVGVEVDAERLNKVISELEGKDINEVIAAGSKKLAKFGGAAPAAAGAAAGGAGGAAEVVEEKVEEEEEADLGGGMDMFGGGGSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFI1</accession>
    <name>A0A8K1FFI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFI1"/>
    <dbReference type="OrthoDB" id="42532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="358" mass="39511" checksum="CED8239208F2BD37" modified="2022-08-03" version="1">MAQVENDFTYLLMFPTATNDAEAKTASSDYWSPPRSPASPRMTTPRRTQLQPQTSSSYAVEGGAYPASYETPAYPPQTSYLPTYAYPPQQPVMTESYYPTESTQWQGYGTYAKHPENYLDPLPMRQMNVPTSSQYLLPEPAVLAAVDADLYDERLLHEALATEYPPRPMPHTTWMGNYAPAYPYEPSSMPMSQYAAPPQLVRHDSSALSTHSSDSEFASTTASLNNETVSTTSRKRKRRSDSSAPARLCRVEGCTKGIRSRGLCKAHGGGRRCLTPGCTTSDQGGGHCVLHGGGRRCTISGCTKSAQWKGLCKMHGGARRCRYENCTKNGQVKQGYCRSHHNLVTRLQQEAEAKAAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFN0</accession>
    <name>A0A8K1FFN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFN0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="19632" checksum="8CBF872F2FBDDB7B" modified="2022-08-03" version="1">MNDHYNVTQTLDGQKYIRHEDDADLGVDGVLYIVMILIEVIIILINVTDVGIVATSVVRPLVNSTRRSSTYASTSTLTSRTSITSKVSGRGSFLSLRKVSLLKRQRTTSFTKDTTQGDRDNTLSKTLLYTDLTSVSYRKPLLSALVLIDAILSSLYVVPNSNVFTWAAPTSVCSACGSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHP3</accession>
    <name>A0A8K1FHP3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHP3"/>
    <dbReference type="OrthoDB" id="166659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF87">
        <property type="entry name" value="CRESCERIN-LIKE PROTEIN CHE-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36722" checksum="6A44D9E149567675" modified="2022-08-03" version="1">MTQQSARGASWASDAEEKRCATPVEEQAAAVEDDRSVVILTTNELEPLENPSVEVIALAMQQLQCSDDWLVQHEAITQLRRAIVHHMSSRLTDEEYVCAFVPLLATACDNLRSALAKNALLALSECFEYLGFARLQSFLVVSTAVRRRSSCNAVSSSEPALLLDVLLRKSTCEKRFLRDAALEAVDQLIQYLASPELIACAAPYATNKNAKVVAIASKIISQSFRRLSPSDLARFTTQEASLQVILAALARFRAGKESTARSESLVCLKMLGESIGNAKMEAALQLALGSDAHTITSILSEVFPSSKKPVSADVGRRGSLRDRMMVAQRQSDTSSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK76</accession>
    <name>A0A8K1FK76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK76"/>
    <dbReference type="OrthoDB" id="109280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33714">
        <property type="entry name" value="COUNTING FACTOR-ASSOCIATED PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33714:SF3">
        <property type="entry name" value="COUNTING FACTOR-ASSOCIATED PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035440796" evidence="2">
        <location>
            <begin position="24"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="221" mass="23060" checksum="3159B3C3672C317F" modified="2022-08-03" version="1">MEAWRCILTLLATFALCASTTAAADLFTAYSSHTDGACTSVPKQIAYVPSVNCSTTNTCASDSSDTKSTPYVTQDCTTDLKKLTATRFASNPWIQFEIYSPGSGCATLVSAIAYLADGSCLIVDNATSSIIATVNTNGSATISTYEGVSCDGSPTKRNLIAKDDLQKTTCLEGVFLVYTSDVTSTKVTTGSSATRLSGRKDALHIAITALSVVLVAAFAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL90</accession>
    <name>A0A8K1FL90_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_005046</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL90"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000113">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="17">
        <location>
            <begin position="107"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW62428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="400" mass="44476" checksum="4F9FAB81EE50C09B" modified="2022-08-03" version="1">MKFSFAYLHRRKDFMASCVRLVVLLGCFLSAYVEGEHIQAAIRRGSVKVKGVNLGGWLVAERWMTEDAEIWQGVPQGIADQGEFVTMQYLGHSVGDARFELHRSTWITEPDIAEIARSGLNAVRVPVGYWIMGAGSNSNANTPNAGQWGVFAPGALKYLDELINSWALRHNVAVLLSLHAHQGSQNGKDHSAAPGGGVKQWSQYPANVDNSVELALFLAGRYRSSPAFLGMSMMNEPEYPTSPSVVMDYFRRVHQQLRSQGDDCVLVTAPMLSEQSPAFMVDFLRGAPNVWHEWHPYFKWGLEGQNEGQLIAAAQQYGSRIAKWSGNPLVLSEWSMGVWDQFAPFADNALYKHFGATQLAAYAPARGGYFFWSWRHSDDSKGKRSGWSMRGLLRAGLLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLG1</accession>
    <name>A0A8K1FLG1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLG1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035439641" evidence="1">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="123" mass="13997" checksum="9D8BD2DAA8E50AB0" modified="2022-08-03" version="1">MTKPNGYVLVVSLLIAAFVRHQQDDERVDDTETSILSTDRSADERRKRLTRSSVMELVQFLCEELQHPSKVLRSEGNDDNRGDPLRLSAVFSRLQSAIAKPEDYATVVDEVLEVLGAWTHRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLY0</accession>
    <name>A0A8K1FLY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012914</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLY0"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16649">
        <property type="entry name" value="mRING-HC-C3HC5_CGRF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="862"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="480"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="596"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="674"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="733"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="539"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="910" mass="102132" checksum="D49A71F092B326F7" modified="2022-08-03" version="1">MDMDVARTLRTNSQRFESILRMNDDETANGRMAAHRRLSMNQAEMGTTPSFEPKTQQSEGEEDEGDERGGNQSLYDLEVLRRRRRMLKASGREGSQQAPVEAQAQTRTGERYATSPRGQNVSYQHELPPPPPPSAGMASSTLQSMPFVATSSSLPQRYSSMAWPSPMPRRPSGLMPGIQHDLPESFDDAFSTSSLDDDAGDFSDDDDAASYGELLDNYQARNLDHSGHSGTRGFGDSYNQSAEEDDDDGADEQDDDDEYDADMHGSLSNRDINMSKAIALKNSMVRNLVRLGFQETVTRGALEAGVQEIEQYDSDCELAYVDIFISLIKMVCDAHQGAAVVSSHRRGSLDRILEGLDDSIHLPFKWPVFDMAQFEFGNARAGTCFESVCVLINLPRVSMDRTEELMEILSCHVFSMIGDPIQVVIPSVNATGRTKGHAFLEFDDPIMARACATAVDGLTWGRGPFGRIRASMFRQYQVKSPIPPTESNLSQSSSNQVSTSGPQQQRHFLATRRQSLDHSVGTDSGQPYTPELSRDDLNSSAGFSSSASFRTSSQLSVSGIDERAFRQHRILSAMRREENEGHRARDDIMRLGELRLSDDEHSGTESDLEFQDPSLGRRPLPPSTRAQRIQRLREQLSQVSTDNLEAPVFPDLPPVPSLPPVVNGEAEGPWRSFCEELIGRNREMQEQLSFARRRVAVLSHNNQKLHLLIDRMERDRDGLLFENDLLQTQLHGYEDHERQQEALMRELAALRRRMRRRDQRIERGMYESGLGGGDFTPARHPTSRAGVVVDLEGGVMSLDELEEQLTQNIVSSRRLDELKEWEQMLEGSLTRVRSIKEEIAMELQKKLAQQAEGQQLQDHKLCVICLSNEKSILCLPCRHLCLCQECSQHQELDKCPICRLGVDNMLLVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMF9</accession>
    <name>A0A8K1FMF9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004004</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMF9"/>
    <dbReference type="OrthoDB" id="272149at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF73">
        <property type="entry name" value="DYNEIN AXONEMAL LIGHT CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="33233" checksum="1833BF473697F393" modified="2022-08-03" version="1">MLRRRSVGLDGAESEYCDLSGRGFTTAQVERTLRVFDTAMAIDMSNNELEMIPTTIPATLMALDVSFNLIAHVRGIDRLKNLQELHLGYNRLSDVSILEFCPLLQRLNLSGNRLVHTRGIETLANLENLDLSDNLIESPEAFRALSLNVNLTHLTLRGNPIAIKSDYRVWVLDMIPSVLILDDKKIRTAVKCKSVEVSATKSLSYARIYDDKKQFMIRNTNRRTPASRPAPILVGNPNIPPKFEGNTIFLQSPTSASLMHDTIPERVRSPEPNFDCGSSTPPAPMMNQSHRRMAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNS3</accession>
    <name>A0A8K1FNS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX59 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNS3"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23022">
        <property type="entry name" value="zf-HIT_DDX59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="214"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="435"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="634" mass="70487" checksum="0D853F5F91506DC2" modified="2022-08-03" version="1">MSPFKSPNLGRRSSPSGSYPYTYTKWIHLSCPLLVHQVLEAMEAMEAMTHAAESVDYVDDRAHADVEEEEEAPVVMLSEQQRAPVDGEPVCVICGRYGEYICDATDEDVCSLECRDICTQRHKEKEMTTVQAKGPETEVAALEEDHKALMERKQQSSELRRSLKIRIEVIGQGTLEIPDLVAEFAGCPDIPIALWSNMHKQGYETPTPVQMQAIPCLLEGQHVLLTAPTGMGKTAAFLIPLISQIIKMQANDPPQTVTFGLVLAPIRELAIQIEEEIKSLVAGIPFMRTALIIGGVPIPPQVHRLIQGVQVLVATPGRLLELLSREDLGLSMETLLDGVRFCVVDEVDMMLSAGFRDQIMTIMSQLSTEERVQFAFVSATASSEAKRVVRDLIQSSDVCLHITAGEIANLGTQAKNLTVNLRIHQKVVWAEESAKKNELFAVLGDEEARQTMVFVESKLGADMLAKAVKQRCNVEAASFHADKSQKDRLLLLERFVNQDIAVMVTTSVLGRGIDLLNVDRVVVFDAPRSVAEYVHLIGRAGRREESFGTSIMFVNAKDASILEEAVRVARQAKGFVSHQVYSHLHALKKPKVPVQRVVDESIRAFKLVRQKEDVEASSRDWKGWTNRTKRSRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FP77</accession>
    <name>A0A8K1FP77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KATNIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FP77"/>
    <dbReference type="OrthoDB" id="304622at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026704">
        <property type="entry name" value="KATNIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027859">
        <property type="entry name" value="KATNIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21534">
        <property type="entry name" value="KATANIN-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21534:SF0">
        <property type="entry name" value="KATANIN-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14652">
        <property type="entry name" value="DUF4457"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KATNIP" evidence="3">
        <location>
            <begin position="541"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="KATNIP" evidence="3">
        <location>
            <begin position="822"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="724"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="780"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="378"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="731"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1253" mass="140045" checksum="8B6E10662042EA96" modified="2022-08-03" version="1">MAERRKWEKPHDGTAFAGGGAMAQTTDDDDPMVKKQRQYLKMLEERNRLKKKLTTTSKTQQRDKEREEAFVTTFNVPAAKTTTATGGAMGQDTVRKNKSSAALLPTKMHQSDVDKASRESKCRSAPSTTLPFRQMPRESSNEDAKDGDAEFHSNTRRAKWSRPVQGTVAVDNRNRLLFVTNDGDAKVDDERVHDDEGDEYSEESFEVFEDEDEEDEGEVKEAGGSVISSDVRYSSAHDDLVFGVGSRHQDTSLPRKAESKEVAIQKQPPADLSATATELFDVIHNLSRSKQHALVDVLRAFKTSSQGDSDIKQLESSIGDPDVWRKVTAALFDDQETAPKSRADGTSQAKATSKAGLTISDVIQEQQKWEEEYALQMKERLMREREAKERMLRDAEERRRAMMKKLEEEEERELEELMHKKRKERIAKLKALEVAKNVNPDSCERHKSDEKTQVNQRNVDAVSSTSKSPRKKSKPGKQASARADSSKPAPESSAFSIATNSPSRSSRPSEEAMVIIPKLSLVGSVASDFASMDLKLIDIRIRLLSTWSSTRAIGLSQVCVYNSNGEEITVDVNTVKVYNQRDGRPLPQSHEMCRTISRLFNGVITTNDQDMWLGRLSDAGVIEIGFCVADMPSKLCVWNYNNRQCAACTRDIEVAVNDRCVWTGSLPQTFGNEDDNVILFTQDTSILKRIEANDSLVTQHGQEHAEEELTSSIVASVRSSMELVRPRTSDGGVSSNTSGSETILNQAEDKGVRPTTSAKRNGAPVMQMPGVRTSIDKWISEEPQGQNMSLSKVLEGSKEEDENEQSDEEELCGCIRGRKITIRLLSTWGDQNYIGLTQLDVLVGKYGTPLTLDKTNIDASPRDLATLGYQGDPRTLDRLVNGVGTTCDDSNMWLIPFNESQHIVIDLKREQLIYGLRIWNYNKSQEDSFRGVKQISVSIDGMMVSPGSTGFVVRKAPGISHFDFSQIIRLYESSSGDKHSRSYADRVSHPLQSRTYKTPVVKQDYEPPLFPQGFMLKFVLWTTWGDPYYLGLNGIEFYDHTGKRIIEEPSQIFARPYSVTEVLAGSKSSSDSMNHDVRIPENLLNGKNKNTWDASDAWLTPLASSLGRSDGNQLYLLFDSPIVVSMIKLWNYSKTPERGVKDLDIYVDDLLIYSGTLRKAPHGNGAQTINRLGAKTIVVEEFSQPLLFTSSQAMVDAEKRRVFYCGTEEQDVLCINEGQVIHESKAMYRKPDPGAEGVVVDLALRPMTAMGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPA0</accession>
    <name>A0A8K1FPA0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dihydroxyacetone kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPA0"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000002">
        <property type="entry name" value="Dihydroxyacetone kinase, L subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011049">
        <property type="entry name" value="PRK14479.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="9">
        <location>
            <begin position="9"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="8">
        <location>
            <begin position="371"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="6">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="60002" checksum="D6C4B7A9C3D682BC" modified="2022-08-03" version="1">MKTKQLVQNADRIVEEMLDGLVLAQPHLTLVEGEKVVLHRDFEAIRERQVTLLSGGGSGHEPAHAGYIGEGMLTGVICGNVFASPTTQQVLAAIRLVAGPKGCLIIVKNYTGDRINFGLAVEQAKAEGYIVDMVVIGEDAAVVNANAGRRGLSGTVYIHKLAGAAAAKGLSLSSIVDVVNKVATTETLGTIGVAIKPCTLPGHDGPSRELGPNEMELGLGIHGEPGIEKCELEDAPVITNRMVERLAGALSLQSSSKAVLMVNNLGASTTMELFVVAKHAIESLKRRGVVVERTVVGSFMTALDMSGFSLTVWKVDGNSELLELFDAATTAPAWNYSPFSTTAKPQSVKPVAAKSTAATFKRPAELSANAQLIEASIRAASEALIASEPDLTAWDAKVGDGDCGHTFKCAAQKILADLESSYPLDNAGSTLRALANSVSQSAGGTSGVLYTIFITAAAVKMESFSSVSPVAWAASFVAGIDAVQRYGGAREGSRTMLDALLPAARALGDVSTASDAEILARLSAVVEAAETGADKTSSISTSKAFGRSGYVGDDNAAGVPDPGAKAAAIWIRAAVSKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPS4</accession>
    <name>A0A8K1FPS4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPS4"/>
    <dbReference type="OrthoDB" id="6130531at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035449852" description="EGF-like domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="232"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="339" mass="34553" checksum="40949112081C6EFA" modified="2022-08-03" version="1">MKVLYVAYATALASLVRGDTVSTTYPGRCLATKDCAVYGSGLECIAVDSNTKGLEKLSMCIPSGSICSGQIAGSCPTFSSWPATYRKVMTVCAFTVVENCDKQIAVTVKQTTTGSGSGQTTGEGEITVGDSSGSSSNTTVECYKRTFTANNENKTVNGIYKCLDARKYIQENLGHITNLTNSHIISCGGDPTSTTPKLCSGQGTCSPKTAFVQEYECKCNAGYSGTLCANVTSNVCSNLGQCGSSGTCVLTAGQTSGTCTCKAGSTGNQCSSCDASSSSACNGNGKCDSGVCSCNSGYSGTLCADRTSTGGTTDSASSLFTMVTATLSTMAAIGVMIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQS1</accession>
    <name>A0A8K1FQS1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQS1"/>
    <dbReference type="OrthoDB" id="118334at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="23277" checksum="3DCAA25A2A299696" modified="2022-08-03" version="1">MLWKGRTALHEATRSNQPQVVEKLVVAGADANAKDKEDMTALSMACSTGSYEVVQTLLTCGVDITAKDKWQWTALHSAASKSSVDVTKALLDHGVDINVPGVEATTPLHIAASAGKFEMVELLLAYGANVNAVAQGGGTPVIAAAAAGNAEIVKKLLTHGADINVTGESGITILHVASQHGCEEVTRFLLDYGLDVDSTTKVYNMDDAFSKGVTKLMSCCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FSP6</accession>
    <name>A0A8K1FSP6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FSP6"/>
    <dbReference type="OrthoDB" id="75751at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="99" mass="11132" checksum="B7F122ED8477E0ED" modified="2022-08-03" version="1">MNPEVEDAVLTSTPTKAASLSPMTRPNALRKSQVFQRRLKAKITESRMLELLDRQLEQDRTGQSVLDSNQDGEDELVCDSTMVRLEGPATPDAFDQRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FT39</accession>
    <name>A0A8K1FT39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Large ribosomal subunit protein uL24c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">50S ribosomal protein L24, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_001349</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FT39"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000042">
        <property type="entry name" value="50S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_uL24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057264">
        <property type="entry name" value="Ribosomal_uL24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 13" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="15">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00035361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW69193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18758" checksum="6F3FA15E14BB2634" modified="2022-08-03" version="1">MAARIPLAFLQGPRRKAKPIDLIKNWHIYRGDVVEVINGPHKGKQGQVVQVIRDQNKVVIENINMHNRYVKSTPAAPGRSYLAPGPVHYSNVNLVDPSVGKPTRVAIRFTDEGDKVRVSKKTGTIIPKPEILKERHTPRRTESGPFDTTPEDVLERTVQDWETTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C262</accession>
    <name>A0A8K1C262_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C262"/>
    <dbReference type="OrthoDB" id="162872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007021">
        <property type="entry name" value="DUF659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04937">
        <property type="entry name" value="DUF659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUF659" evidence="7">
        <location>
            <begin position="183"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="657" mass="74483" checksum="1006E236F40337E2" modified="2022-08-03" version="1">MAHEANGATPFGSLTDELQAAALEDHAAEPSPHPTEQEVMAAQLVAQQAPSPTRHKRKRKGGRQKDPIWEEVSIEASGAVVCNRCHMVVHRYGCTKVERVRAHFKNKCLFADEVKFSLEARMKGKDVPGEPKTPNRTEYATKMGIFKRRIAQWIFSSGHSFNEVKNGFFRSAFTVLRPGITLPTQYELETDLLELEFNASVAKVSRSLSGKACCLVLENWVNSNGQPMINYIAFCENNSYFLEASPAQSVDNNEFLVDEIERVLNKQKRTIVYGVLTPLASVVNKSSRELIQKKFPQCVFYYGCIANALNLLMTDMCKILPWLETIHDLVVLMIKTFQQNAKLRNQLRSLQYTQGKPPLILPEEAGASICDTLDSVLKSERELVELASRRDFIDSGKTTEEKGILKRIQDFVLGDTFLQDLLNALNILHPLQQQLSQLQNERVPISYVYRCFLDLLSFYAQMELVNKKDKALIASCVNDRFNSIYGDCHGVAYVLDPVFLGADMDEAKVREIEEYIVSFCSQILHAIGIDILDQLAKYRAMVQQLKECNQPYWDLLVSGKVRPFDFWVERRQFPQLQQLAWVVFALPVANMVPDQRFAPATADLHSKFHSQLPSYKLDKLTHIHCNAKYLDPEAKEPEPSSSMVVLPDLDDPNNALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3S5</accession>
    <name>A0A8K1C3S5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 18 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008564</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat UTP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3S5"/>
    <dbReference type="OrthoDB" id="1935146at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000121">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 18 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="171"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="51402" checksum="819BD2B84C0C0F66" modified="2022-08-03" version="1">MGKKSGAKKQANAPTVDETRLAEQLFTSANAGVSTATTAVKRKQSKQLKPVWVDDDDGEIEVTLDDERRLRKLRKTEDDTVDGHELQQRLKKQFASGHGSVSWADPKNFLGPQRGNDLLSDSEDEEAIGTDTIVRSTGKMLASEHDVLAQGTLEITRMKDANQHAPSGAVVQSVEFHPNGQLLLTAGLDKTLHLFQVDGTNNARVENVFVKDLPILSAHYTLGGSRVVLSGPRSYFFSYDLEAGRITKIPGITGRKDRKLERFTVSKSGDHMAFLGSDGYMSLLSARSYETIGHIKMNGDVRSATFCENDRYLLSTGSDGEVYKWDMRTRKCVFVHSDEGSLGNFSIAASSKYYATGSTSGVVNVYDNDGVTVHRKPRKALMQLTTQVDGLKFNPDGQILAMSSRDTRDALKMVHVPTMTVFANWPSSKTPLHYVSAMDFSPNSGYFAVGNARGRVLLYRLTHYGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3W9</accession>
    <name>A0A8K1C3W9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008623</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="268518at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="10">
        <location>
            <begin position="336"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="1368"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="1406"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="1540"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="2595"/>
            <end position="2628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2347"/>
            <end position="2401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2545"/>
            <end position="2586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2347"/>
            <end position="2358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2362"/>
            <end position="2374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2389"/>
            <end position="2401"/>
        </location>
    </feature>
    <feature type="active site" evidence="6 7">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="active site" evidence="6 7">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <feature type="active site" evidence="6 7">
        <location>
            <position position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2657" mass="297851" checksum="1A9071BF9CF3C327" modified="2022-08-03" version="1">MMTAMEADDSMRYAAEEQQSTRDNATETEATGVEETRKRKHDAISRSARRESAAEAFLMSPLKTRRSLSTLGRVLESSIRVVVDNEETLSARLEQASKMWVTVRDMSWMELVDFVERRISYVVELVEAMLDTGYFPLQQLCFMVTAAVLCQLQQRDERLLSAFVVICREKMGEAEWWMMDLLPLKEEIAWSDPLVAREHVIAMNRRTELCTSHRVLRCWVSPQKKEQLTRLRIDKWLDFGATTATFYWNENGNVVVVNVPYACVDGTEIDHANNVIYMRTKQLDRLGGVRLLAFSATAPEFSSLAKVIADRKLPGSLEENEERTPSKSTQNLLALTPEALFYTGSTVPSKGGSLHQAKVLALLKNDKLRWERPQYAPDDADESNQNESDEPATFSSEQVFASDAKLFSDGVCSGDVIQGNLGDCWFLSALSVVATRSDLLEQTFWRGNAYKTKGLFVCKFMKNYVWQYVIIDDLLPVYGFSRTKEGKPYFARCRDPNELWVPLIEKAYAKLHGSYEALIGGFVDVALNDLTGMCSEQVIMKAGYPGFGEDPFAPARPQQRKGDPFWDKLIKYKQGGTLMGCSIQPAPTSADKAAAPESSAGNGLYYKHAYALVDAAEIKTVNKELVRLVKLRNPWGMGEWTGPWSDSSDERVQNHDIIEQYFKILKRRVGSNTNKRVFLSLNGRGELQIDEIAQDEVIEMNANDGTFFMSFDAWMQFFTHFFAGIDFPDSWQGRRVEGCWNEANCGGNTTKSTWLNNPRFELALEERCHLFISLSQEDPRGRENLKIVPIGLHVCSLTQLSDTPGKYEVKEPPGKPDAYYRLYKDKDRTEFKKGIRPEVLPPAIIPGSVIPGIDDDGVPQAAYTFKQAVSADVTMEPGRYCIIPSMYMRTDKDTGKTNVGSFWISVYSDKGKFRLEGGEKIVEEEEGDDDVESDAMKTPYGQRARLRRSTLNSPGKMSDSSVSTEAISIVEKRRRFEDAKDELLAQAKSKGIGLRELKLEFAKSGIVKKADIRRKMVAVGFKPDELSDEKINVIFSGLDDSNSGAINSDRILNMFEAEIQEDHAACEIPEIEDDEVPQKLHQEGELSIELRGAKGLSLNSATPLQSGSKRKVHLPLIEYSSAEKKFRQKLAMQMCEKDPVLAGDLSLIRRKTGWLPPGATFSASKSSSKRVVSNCPFEKLYTLLNGEYDTLRSAQKEIAADEEAIRSVVSVNPTLEKLGDIRRKSTSLPIAVSTFHKTDKMQKLETKRALRLVRLQKRKQEALGNRMKTADLPRLIGGHKSGSSHVPCVDCGVRAHVPDLNAKPSSPPSSYMCSGANCTSVLCSSCYLSLPHGKKLCEECFEHELVPVEVFGGQLRAILIEKLGSSGSDRSRVESLFHTLDTDDSGVLSADEFSQALQTLGIQPPLSDEQQRSLFVQFDTDGNGEISLSEFKDWVTKGQVWQPNDNENRFVGSKTTDAMGDVISPLLEYLINAACDAATMSDSLTSWVTTRNTTRTHTLRIGAVSDPDKNRRNEVGAVLYQRVVGLENTVVGGSTGDARSTDHDIEQLFQRHDVDQSGMIDQSEFERLLSALGLVVTTEDAQLLLYRLEMSSDRNGLVDLREFRTYIQRISTGVKYTSGSSELVHLLSGIDFVVKGDTSKRETVQEILQQLHWNMRRSEKLEVCRHLRALGMTVTSGGLQRLMNALHFREVSPGEDRSSTLQEEVNGQDERLGVKSCGDVLNAILFTAPSDVIADLKAFSPMNVCRQIKVHVDSLTKTASIESIWRSVFELTPSHSMDQRDFIDKMMSTGFTVTTTLPEGQALMRRLITKLHLALCLDALRSEGVQDEEVYSDVVTFKVFTMMIRREQIDEFEIQFAQGLTNYLRLCRGGQQYMVTVALERDLLVLRAVDPVFKYEMDFTLSPGEYTRAALQQLSETVWPCNRQNASTRERQLVTTPSGLITAICFPQMHEALRTLVSRLRVAFLETADARRCITPFLTLVESDVFVQELRGQLERAKLPFFSSVSPTTLELSVDGALLAQRNRRSFQQYVAEILYSKATAKALLSFIKFTHSSLEVRYEIVGQDGAFDASWQDLQALLAGHQHTFAVLELRPQGDVFATAVDRRGGNDAPKWNFKTSVVLREPELSDHRIDRPVIYTDTVKISSLPDGSSSKPVTFSPVNGQAGHFVILNVRKAVPEKHGDRPRLYCTAYDPFTSSDYAVKGYPANWSVDFFNHAVTPDYEDKWNELIKTMQLGPTLTPKVLVRVFNKRGKRDLLVGECEISVSSAIAHEGYVFDDWFTLLDAKVPTETRGAINMAFQFNAKKSIPIDGIMLKPLEVVDERPAQITAPHPAESRLRELEHALLTTDKAKHEAEEQAKSMRQRLQQLTAAQSSANDEEVSKWKKKLDHVRKEQEDQQRAHDDRLAELKAELERLESAASAMPEPSPRRTVPILNMKQAALGAEASAHDILSSMKEILLNRSPERPYNGLKKALAAVAEVPGKIAHAAFEDALVDFGLGLSGAQRMTLLSTLDPEFKGRINIEDFFIKLCGDAEMYASVANLRSRQAPPSPVAKEHPSPERPASAPMPASPTRSAVPAPSRPHKQSWNEMKKLMVLNIPEGWEMRFTANGRPYFCNHANRSTQWKHPVPEVDAKYSEWVKENVSFFQRLSSSSTTTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3X6</accession>
    <name>A0A8K1C3X6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008632</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3X6"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000011">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="KRR1 small subunit processome component first KH" evidence="10">
        <location>
            <begin position="67"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="KRR1 small subunit processome component second KH" evidence="11">
        <location>
            <begin position="149"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="45920" checksum="5D424AF3237AF45F" modified="2022-08-03" version="1">MDQFDDVHASGNALLDESVKKSKNHRKDKPWDSEDIDHWKIDSWEDEIDDDKQPGKKLKMPTLLEESSFATLFPKYREKYLREVWPIVTKTLDAHKIACELNLVEGSMTVRTTRKTTDPYIILKARDLIKLLARSIPVNQAVKIMQDDMQCDIIKIGGLVRNKERFVKRRQRLVGPDGATLKAVELLTNCYVLVQGNTVSAMGSYQGLRNVRKIVEDCFANIHPIYNVKRLMIKRELAKDPKLASENWERFLPEFKKKNVQTKKPKTVHEKKEYTPFPPAQTPSKIDKEIESGEYFMKAHERKAMKNKEKAVKRAEEVEKKKVEKQSEFVAPNEKEISKKRKHQAAQAEKKRDASSIEALKNKFLNQKTATKSKAGGSSVDDYLAVPAAKKQKKSKKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C414</accession>
    <name>A0A8K1C414_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aconitate hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010619</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C414"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170034">
        <property type="term" value="P:L-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170038">
        <property type="term" value="P:proteinogenic amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="6">
        <location>
            <begin position="93"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="7">
        <location>
            <begin position="542"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="468"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="674"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="706" mass="76389" checksum="D62D805117859FA0" modified="2022-08-03" version="1">MQSSAQAPASSEAPRRRPMTLPEKILTHGAVGLTQPWVEPNQMLCVKTQWTLACEITWKSMDKTYNDMGRPRIWRNDRFWLAVDHTVDPRVNHLPKQQMMIKASEDFAKEAGLTNYQPPNTTILHTEFYRQRAQPGQIVVGADSHSCSTGGLGAFAIGLGAADVLMPVVTGETWIKVPETVKIDFVGTPPFGMGGKDVMLYTLGQLKCNTVATGRCVEWGGNIGALSCDARFAISNMSVEFGGIAGVFPGDERTAAYIAKREGHKEEALYFRADPDAEYADKFEIDLSNLEPQVALFPSPDNVKPVKELVGMKLDGCFIGACTTAEEDLVLGALVLEACMKQGLTPVNRGHRRVTPGSQIIINTLREHGLIDVYEKAGFTVGAPGCSFCLGIAADVAGENEVWLSSQNRNYRNRMGKGSIANLASAITVAASSFSMEVTDPTPFLQYIDVEKFHRVVPRAERLPITISEPSPELPVAGEESADTESDTGASTDSIPDQIKGRAQVFGDNIDTDAILPGEFLIENDVEKLGKVAFLYTNPDFRDKVHQGQNIVVAGHGFGCGSSREQAVTCLKGAGVQAVIARSFGYIFSRNYQNFSLLGIPLTDDRFYELAKENSDITINMKGRTIEVAGEVFRFNMSLFEERLLAGGGIMPLYKKYGNRLFRVAVQEPQDPLQGGGGCGSGGGSSGGCETKTPAVGAGGANDLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C430</accession>
    <name>A0A8K1C430_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C430"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="530" mass="60889" checksum="AE9DB151CE3FD18E" modified="2022-08-03" version="1">MPSVQAVSTGLAARVDAVPAQDGAFATIFYDYGEDSDAMLLAIRVLMRSIRDSQTKYRKLVIVPQDGLLPTSKQRFQQDDPSIEIVRADIPNIFRRNSVMDPRAQLLHMRNKLVLWDDPVLAKLQRIVYLDPENLVLNNFDEIFACAQFCAVDNGQSIVYSNSLLVVSPESIAARNLYSDAIDSFMISGREYNYIGITQGFLPGLFQALEESPLFNVDQDEADDEFEKEAAKSVVRRLPFYYSINHMVFYERMNWDLYKCKDKNKSSKQIPGPLLSYKYSGATIKPWFWMPYVYFEVNWHWLDMRERLQEDHVGFFFSKLISQSVLFVLSWFAYVAICLKLRSEPNGRMRRLSSWNLPGPTTTPALSMDLLNSNVVRKACQFSCNVLYAISSTPIFSSFVLVLVILWTSIYAMPPLMHPRFAAMLWACLLDSLVMTVLVVYHVAHMLRTTEWKREEAPSTLGLLFEAVFEGSKRLPLLLLVQVLFLRYVGNTELFANPVLRPTVLILLLATLCMIQVRFFAQEMRRLARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4D1</accession>
    <name>A0A8K1C4D1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4D1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="23556" checksum="A3D974A17B7B2173" modified="2022-08-03" version="1">MASTANDRFRKKPRLSPSAASTASHRVKNGVAGASSARPQYAFGSRLPLAGKENVNSNTLKTTVVSHSSGVLLKKSEKDSQMPASAMKNRLKRPRSATNASNEAVSTRTAMPSGIPAPQINVQASLASSKATAAVKAPQSEPEVDSVTTENEPEAEDTTESVEEEKKKKEEESDTAKETEELEEAVESLFDTLDASRAGFWKQRQAFVLTAMKDMQSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Q4</accession>
    <name>A0A8K1C4Q4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006398</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Q4"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487667" description="5'-nucleotidase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="5">
        <location>
            <begin position="315"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57340" checksum="B3407CC097D875D0" modified="2022-08-03" version="1">MKIFRSFAIALVAALAGTAEAKRNLTASLEILAYNDVYELLQDSVNGMNVGGPSRVVPIAEEMRAKNPNSLVLFAGDTMSPSLWSTQFHGMQMVEAHNRLGVDYATLGNHEFDFGIEGFLNVSSASNFPWLNANTFEIETGALLRGTEPRAVRVLSHPEFGTIKIGFFGVMYDMKDSSKGLFWSDPLEAAKRQVDILRNREKVDMVIALTHQDLADDNRLSKDVKGVDLIIAGHDHTSMLQTNFGAPYLKADFDFRSIWRSKVDYFKAEGSNTAAFRMDHHAVQITEDMKTDAKLDAVIDGYTKKIGELFKRQVGTICEPLDLSNKVVRAMDAPIGHVFADAQLNFYGEGTGDVSLMNGGGIRTDRIYPAGDLTLGDVMGWSPFGNMVMIIETDGASLKKFITKEMLGSCGAGVVQLNGFYVHTAGIKYAFKCTGSAKGEITSIEWFEHPTRTGPVQDTDKFKTVLSDYLYNTEFMTIPGVSSTVVISSAEGVRIDAALEAYVKSLPNAELCEKGPSRNSVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C585</accession>
    <name>A0A8K1C585_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C585"/>
    <dbReference type="OrthoDB" id="63077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="791" mass="87449" checksum="87A508D68EEA6B67" modified="2022-08-03" version="1">MNAYLQRKCRSEQQLMNELSKLLASKDYASKKMSELLKELGFYYVSPLFVKIPHSVLKDLSVLLTHLKDKKEDLRIAKLVLCFLARIVDVFELRYHHHALTSATSREASRAQSFDMAMSTTSNLMKIMETSELNHASFPRQATCLKLYAHLCRIFQRSDVLMLRIKPMIQKSPVWGLLTADKKVTASITGKKDFLTQIALLGAAFHSIRFHLTTDEQSYHFLENILQAAFLPNAAASRHAAATLLQLFETSNEQAKQVTAQFEVFFARFRPATLRVGDQLATIYLVRLCGQLSRLPITGDSSSGASQTRAASSNLSNLLDFSFDTGDAHGHSASDAPAASPPPSPIQRQRRRVEGITVSSTLSSRLRDLFLDILCAPDVMGGVPKAVLLVTIEEAVKDANAECCILKARGNVSLFEIAASLLLKVLGEAIATQNVATLHRVVRTVQFTAEALDGSVLQMTGTTAHHPQFMDRITDQIITSGLLSHANAFVTCQSLRALVWLLPRASSGVNDKWPMLTQRLRDLPQAQLQPEARQTIAEAFFHRAVTQPSLHQHAVDHEMLGKVMQLTLVWFQTQPCEWHAAMLVRIWTTALRKCLATLGDAVFASINAVLDFQHRTLRIATERVHQSTLLFLSHFGVSHLIQQSSLSWFHALVLRLTKHMLLSASLVTRRLSVNVLAEFHVQASQSGCQEIVSHVQTLVTYLTQPASSSSSSTDVVRASRIHTQEVKDTLGIQDALRQCLALRLPSKAPATVSATSVRNVEPATPFAAAGLNFSSTQQSTSSVLSAFDGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C590</accession>
    <name>A0A8K1C590_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C590"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="5">
        <location>
            <begin position="126"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="225"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="292" mass="32562" checksum="0E4956B50DC09E88" modified="2022-08-03" version="1">MTLTSGSKRQRLRQCLRRPCSAWASESPKTKPSLSTVASDQSISIGEDQEDVVKFVQLKKAASMDPISMEETLAPGVSTRRPASLSMDSSATEKLTSVSPVANVSPSNSCRKGVVYGSDGSVLSCRFCEILRTQDADFLYEDDTIAVFRPLYPVADSHVLVVPRCHIRNIKKLTQDHSELLQRMKQVAELVLLGDNVASPTSSSPKPTIECKYAFHSPPFNSIDHVHMHAFRTNERAFGCISAIKYRTETWWCRSFDEVVARLESANQARNLTQSRQHKVMYTYANDAIATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7F1</accession>
    <name>A0A8K1C7F1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7F1"/>
    <dbReference type="OrthoDB" id="61749at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="413" mass="46357" checksum="FCB32A6672B6DC1C" modified="2022-08-03" version="1">MHLVSVQMSKMLGRGHDDRGNAAFYGGVRATRSMGTLLTALLGLFLCGAAFGGVKASSVPFYLTVNGVYRLYPREDLVGTVDADVLWSEYYAYIMSRERTTPLVVLFTSEECEKAPQESREGDEDEGDDGLLWGFTASDDDYAVHEACDAQLARLSIDVETEVAETVTREYPDLPVLLISKKELSQAFHQHRVPSSPALMWFPLRSSKTFQRFAHPKTNYLNISDSLASGKSVSSAITKFLRRSLVEGGHAMSGSTASAEEDSSFLGFLLNMLPLVALFAYIVLSIFEHREVIFKLLQNRFLWFILTQGVLYVSLSGLFHSIIHRVILFYAHPNYGVMLIHPSGRKQFFLEGLVHGSWSFLISFGVFTIVDVMPTVRSRTGREDLFRWSLLFVGASYAFLQLTFMSKHNWLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7G8</accession>
    <name>A0A8K1C7G8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7G8"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16677">
        <property type="entry name" value="RING-H2_RNF32_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16678">
        <property type="entry name" value="RING-H2_RNF32_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042862">
        <property type="entry name" value="RNF32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="306"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="369" mass="42829" checksum="B05FE7C2E5928751" modified="2022-08-03" version="1">MKRRTKRPEAGSYSRTLKEPSTIINAAALQDHLVRSMALNTLACRPKPLQRAAQVSLAKTQAQKDSRHESGMYVVQTQSARRSPAMMVPSSEYRKVWVEAPPPKLSRDDWERCENQALERGDVNHPCSICRESFGVQEQVILSCSHMFHLACIQSFERFLRTKQRVCPLCRKDNYQKRATVKGAVIHRDKCALRIQTMFRGFRERRRLDSLWHQFYRQGKGDPVRRRRFLANRIGKTTDRLVGAMRARDDSIDALLAEFDKTLSLSRQVFDPSQPQTDDDPSFPTRRGVDWLAVFEKARLRDERECPICINAFSVDMTNVTLLSCSHCFHHDCLHAFEDFNIYEVPLCPVCRASYQKQSWDQFRTSTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C825</accession>
    <name>A0A8K1C825_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PAP-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C825"/>
    <dbReference type="OrthoDB" id="407432at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="9">
        <location>
            <begin position="200"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="9">
        <location>
            <begin position="352"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="8">
        <location>
            <begin position="513"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="68712" checksum="07FEB2E31089698F" modified="2022-08-03" version="1">MSRINEETKTEGLPEVATVEWHEAAWFVGCDGDVCAAYEMVAKCFGVGDVGALQDADAVRRIRRIEALIDRVRSCVLSYDEEEAHQTALTAIVEDAVAIVTALDEEPLKQTVIGPVEKAETVNLMEAITELLSSQRVSPLILDKWATVFDTTRPTRVLQKTIKSAVFNRLNDQLHDMIKPSERTETQVLPLRPQSEHWEREIQEFLVTYAVDPDDESARQRIAQEIQALVRTDPRWNESEIKIVGSTATKFGLKKSDLDLCLYVEQGDPDEQRENQQKNLRLLELIDKSSKSVKSVSNSLVAQTKRGSDHRVKLTATFLSHWKSLVEALQHQHDQSRGVKRGTAPTMASRHKNKEIFDLEQLLKRGGCEILLVNAGSNAPIIQFFPPGSDISCDLGMGNRDGLINAELLRTYAEFDGRVRILGVLIKFWAKERGICDGSKGFLSSYVHVLLVVYYLQVRVGMLPNLQHPMLLQQSKVSQRNANAGEVSFCADVEAARVFHKATSSFDRATGLSIAELLYGFFVFYATEFDFETRVVSIRAPDQRISKKLRWYNSSFKDWRISIENPVEPDRDAGAILEPKKQKKTLDEFQRSYELLTEGESFLASVCASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8D3</accession>
    <name>A0A8K1C8D3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8D3"/>
    <dbReference type="OrthoDB" id="64332at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042282">
        <property type="entry name" value="FKBP6/shu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674:SF1">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="7">
        <location>
            <begin position="432"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="234"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="527" mass="59954" checksum="D38F409FB69283A7" modified="2022-08-03" version="1">MPTPKMHVDDVLRLRTTLERTDKATQQFLAPLLGVEPIQHLLITFLQDTSRSFEDHVWDPATQDVLCRLRDHPNRDMMQGHKSEVVDMFQAEMQRRFGSRDYIADIDAAQEDGKRKFKKGDVYPAMNAFKKSLEALLAFHEDDYYGEKIDPCEWEEQEWRVRYVTLCCNIAVCAIKLKDGATIELYANKALAVDERSSKALYALAKLHVMDHMYEDARVVIEKALDFHPENKLLVKFQREIDTAELKEMEARAELAEQKRLYDIEQQRKAEERAKLAEEKRAEIARAIEVTPLPALSRDSNFVQVLQNYFNRIKHQVIIDFTQLHNPDDGEPPLFACTVSDGTTGAVLAGAIEAPSKKAAKGKACKIALLKIWEMKRSLGTLLPEDEERWEAYERSLQDGPASDSPDSQQGAFDDVSAGKPLCLTVYERQFEVQILLNQLQMKRQLKVELEVENVSPSPHTTAFKCVCTLNGQIKGEATAISKKKARAEASQKAFDEAVSQGLIQFERPMEYKSESENDESTTQALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9I6</accession>
    <name>A0A8K1C9I6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9I6"/>
    <dbReference type="OrthoDB" id="343609at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21312:SF28">
        <property type="entry name" value="OVOINHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21312">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035443565" description="Kazal-like domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="7">
        <location>
            <begin position="30"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="7">
        <location>
            <begin position="88"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="7">
        <location>
            <begin position="198"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="26291" checksum="DFF1279402AD90B6" modified="2022-08-03" version="1">MKIHVAAITIAVLGLTDSVISAQGNNSSTSTATTGCSKQGECTSDSQPICGTDGQTYSDICDFTTAACKAKSKNEALDKLFIGACDDLDANPYCGLSCTADIDPVCGSDGLTYTNECVMLAGRCDIPSLMQAHAGKCKASAPRLRCKAVRIKLVHIRTDDEEVDASEAEDDEEVDASEAEDGEEVDASEAEDDEEVDADEDSECEEVECPGIFDPICGSDDQTYSNDCFFSYAQCQDPELTLKATGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK2</accession>
    <name>A0A8K1CAK2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK2"/>
    <dbReference type="OrthoDB" id="173909at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="29924" checksum="39EED7CDD38D4770" modified="2022-08-03" version="1">MFRVWVIVLIVIDNGWKLTIVLLNERLAAIITEFTYVTSFEIMCSTLLGIYLTFDDIMNICVLKYGLVDGQRALNPTTPTILSFYSTHTRYSWGDRSNDYAALHFIYSPLAKIMSYGILFSFIIVFLRLVFTVARKHRRGVLAGEVETFWRSYQRNSAEVFMNTPMRANALIRSQRIMSYRFGKSVFIRPFVYLEQNFYITRGKFRARPAIPFLMNEDAEVGADVDTKSCMLQGVFRSENSTKLQKKHRGHDVQIPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAP3</accession>
    <name>A0A8K1CAP3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAP3"/>
    <dbReference type="OrthoDB" id="63226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="33"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="244" mass="27647" checksum="320904DAED4567E2" modified="2022-08-03" version="1">MPKATRYSPTYERRRVQSYGATRLTAGTPTGVGIAVESYLRIKKRGALTWSTRYMILRSGQLVWFNSKQDAQWRRGMVDETHVIEGRVMSVRNEPCLVIKSEDGKELIARAFSRGDLAKWITAFERLAVKREAKQSTIRSSTCTTEASPVSMMDDEGSVSTLSSSEAMSPEKPRVRRVTFHRNVLVRLIPAVTDEEASALFYSREDMERFSAQAASILYRTEEAVSCAYQSFRPSSMSCRKEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB39</accession>
    <name>A0A8K1CB39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB39"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF252">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="84"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="212"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="293"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="48330" checksum="5373994EEE01B721" modified="2022-08-03" version="1">MSFPTIKLIYFNGAARAESIRLAFYIGNVPFEDVRLSFQEFGALKETFPYGQLPVLEVDGEVIAQSEALLRYAGRLSGLYPVNDPVAALKIDELLGSTDELKSKMIPSIHEQDPDKKKALREELANAVIPRFLGFVDRRLTLLKKHAVFQRDALFIHELLINSFVSWMKSGVLDHIPVTVCDGYTAVEELVTKVTNHPKVNEFYATSQNVAPRLKLTYLDGPGRAEPTRLAFLIGGIEFEDERIPEYGDIAKRGSTLPFGQVPVLSIDGEVHAQSHQILRYAGIRAGLYPSTNFKKALRVDEVLRLVDDYFNTIALTYAMEPEAQHSARKLIAKETLPKMFSELDKRIAGWGGQYAVGDELTVADLLIYCWVLGLKSGYLLAIPTTIADGYLHIGRIFDQVSNHPTVQEWNQKTAPLDGFRKWSSPSRILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBI0</accession>
    <name>A0A8K1CBI0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="153118at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="718"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="769"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="853"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="877"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="952"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="89"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="407"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="719"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1052"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW59958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1296" mass="141070" checksum="0BC2F7682FCB39B4" modified="2022-08-03" version="1">MKDADQRDSGAYHLVETPRASASVRQITGDDDAAKTKKWSASTAAIDMTKPHEGSETDASDKDPAKATRKYGFFELYRFATPFDKVLLFLGVLCSAVNGAMFPLMAIVLGDTMQGFASIPVDRDAVNRAALNYFLIALGLFFTHYFGYVLFHVSAERQMQALRRESLKHMLYLNVAWYDSNDALQLSSRLTGDTVRIKLGMGQKLGEAVGFTSQFVVGVIIGFVRSWDLSLAMTAVMPVVAVSLGWVMKKTREKAEWAQKKYAEAGAIAEETLGSMRTVASLNGQTRAIENFKAKTLETETENIALAKVVSLVMGIFLGNIWLMYAVGLWYGGKKVSDNEAEPGAIFAAFYGTLFGTAALAHISPNATAVSQAAGAAEELFKILDTQSTIDASKDEGVIPESCEGAIEAIDLNFTYPSRPDAPILKNYSVKIEAGQTVAFVGASGGGKSTLISLLERFYDPDSGSLLLDGRDIKTLNLQWLRSQIGLVSQEPVLFATTIFENIATGCGKSVTREEVVAAAKLANAHNFIMSLPEQYDTLVGEKGVSLSGGQKQRVAIARAIVREPKILVLDEATSALDAESERVVQAALNDLMDKTRMTTLVIAHRLSTVRRADKIVVLGDGHIVESGTHDELLKIEGGIYRNMFTLQQLHSHEEDEEIALAGVADIEAADATDIQRSSFVSAKTVISESDVESNEYESKQFGFTQLAHLSKNEKRHFALGVFGSAVIGTIIPVSAVLVGGMMTTMTQDYALFQNTQDRSHLDKIYDDVVVYGILYLVGAALIVSFLWLQTYSFKYMGEKLTKRLRDMNFAALCRQNVGFFDDKKHRTGALTADLATNAAKVAVLSGDSQSRLSQGLFSVCAGIVVSFGWGSWELTLIMLAVYPLLLLGNYLRFIQLQKQDAASDELALPGSLASERLSNIRTVISLGIEKESSDRFEDLLMEPLRKGSMEAHINGLALGYSSSIMIATYALCFWHGGKLVDEGKITFGELIKTFMAIMLSIEGVAGATSYLSDARTAFKAGSNILSLHERSVPIDAFDESGLQPGQVEGKLEFEDVYFRYPTRPDVTVLKNYNLTVEAGQTVAFCGPSGGGKSTVISLIERFYDPVRGSVRLDGRDLRELNLGWLRHQVGLVGQEPTLFIGTIADNIAWGLGSEPSQEEIEAAAKMANAHDFIIQFPDGYQTQVGLKGEQLSGGQKQRIAIARAILKDPPILLLDEATSALDSESEKIVQAALDKVVSLKRRTTLIIAHRLSTIRNADLICVVSGSKIMEKGTHTELLTLDGLYAELVRTSSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBR6</accession>
    <name>A0A8K1CBR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBR6"/>
    <dbReference type="OrthoDB" id="126400at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="50509" checksum="0BCE343E46FF5C54" modified="2022-08-03" version="1">MTEDAEMFEAMARLLDVPVDAQATTDVLMHLLDDDDDCGVSSAHQAPVSTTASQPEKRKRRPGYNSNKARDARKHELVQLRSTVAQLECVATQLRQQHEKRSKSTRSQDLMVRRSVWRPIAARQLEERRRAEETNTQLRIQLADQTKLTESLQRIVTRPSVTQGFIRCGILVPRRGYVPPTYQYDPSMHKEMLHEVEANYNEVDALFRRLNLNDEEEQSGDLHVRRNDKAGRFESHQLEILPVSAHVAADIVWQHYAEHMSSVPFRRYYERTTAAGDLTEDTIIERICVELQSSETITTSTQELQVMRRYTEKDRIVIVWYCTMRPVLYANQEVNPLDSLERGYMVFEPSKTLDPESHSVLKMCVTHKRYDEVADLDGVQRKAVESMVSHGITMASALHRSIENMVLERRTPRSPTKHETKQKVVGVSARFVECSDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCB8</accession>
    <name>A0A8K1CCB8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCB8"/>
    <dbReference type="OrthoDB" id="601405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017054">
        <property type="term" value="C:negative cofactor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042225">
        <property type="entry name" value="Ncb2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138:SF1">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="3">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="134" mass="15108" checksum="00B5254E07FF7CDA" modified="2022-08-03" version="1">MALPRVSIEKLLRDVLPEHFMLQKETTDWVNECASEFLRVLGDKANETAEASAKSEQYRISAEHVAQALMELDQEKYLEQIRAGESSRQAVTASKRQRAATRKAALKQASHEDLLAEQNALFHQASQKAAKEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCE5</accession>
    <name>A0A8K1CCE5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCE5"/>
    <dbReference type="OrthoDB" id="10259249at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38150">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38150:SF1">
        <property type="entry name" value="PFU DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421222" evidence="2">
        <location>
            <begin position="22"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="700" mass="77512" checksum="0E52BA3536F071A6" modified="2022-08-03" version="1">MWTKFSSSVLLLALLAARSTAQNVAVNLAASSPAASSTSSSGAQTNSANAKRDVLITMPIAIDGTTRNLQLLRGESYEDAAISFAQSVGILQHADEIRVREVVGQLSGLLKGKMEEIEAEEAAAAAAAVPQQVLQLTLPLTINGFNSELKKYEGESVEAAVERYLYASGYTMEVMRELYPQIITLVNNKLEELQPPSKELFAFTLTIDGREVVTRHFENGDPMEEAQMTLRSIGVQDAELINRLAPQIAKEISRRIAGLGVQPTQEQEPQQVQQQAPVAQELFSIPLTMNNRPALLVHYEGFTSRESAMRFLEENSVNDANSMNQFVPQLVQLIDNRIAELANQEAQTQPQLQEQEPPVQPPHQVSALKELFSIPLTMNDRAVVLVHYDGLTSRESASRFLSENGVTDANAFNQYLPQLIQVIDTRIAEIVKQETEQAAAAAAAAVEREAEARRAQRVPMVRLPISLGNGHEATLEYFDGDSVERTVELFLSHIGLQEGPDFVANTQRLSELVRREVKTVIEQQAPAQETAPVQPPQALRPQPLLTLPITIGGRVFNLEYFAGQEPAYVANTFCVEKYEIVRAELGLQFDGNQLVECKNVLESTIRTQADLPQQQQQEPVREEPPQRTEPQQPQASPNSRGDHLFTVDVDIDKETTVQLRVYQDDDPEQVARAFCHEHRIDLANIPALVDAIRDQLASLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM0</accession>
    <name>A0A8K1CCM0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000712</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCM0"/>
    <dbReference type="OrthoDB" id="10253329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052650">
        <property type="entry name" value="Zinc_finger_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36886">
        <property type="entry name" value="PROTEIN FRIGIDA-ESSENTIAL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36886:SF8">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="9">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="326"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="CHY-type" evidence="10">
        <location>
            <begin position="600"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="735" mass="81497" checksum="5923A616F2F73738" modified="2022-08-03" version="1">MADTTTSNTTNALLQNELTAVQRRYHGQVLPSTEDGVTQVRCFVSLSDPDLPTQFKGEAELMVTLPADYPASAARLDLCGWEQRMSKTQFRVLNEATTARAEELRGVYGLRKLLTWLDNNFYRLLQSVKEEEEEAVVVQEEQKADKAEDDSDAKNESTEEAKDSRRRRRCPFFARGKCNRGAKCKFAHTTKQPAATDKEVDSRDASHTETQSAKSEETPSKPDADKKKKKKKQKKTDEDKGADKPEPAVTKKTKRPCKFFAKGKCRDGDQCKFSHEKKTKNASEETPRPAKPAPGILVAVIGEPTSPKQTAASVEVEYLPLDPKEWTTEQQKALDTALMKYPTTMDKKERWTSIASEVNGKTLNDCIDRFKLLCQLAKSGHLSEMPETPPPAPVEVTAKEEDSPSEEAQLNAKIIPVDQRVPVETEPEVKGTQIRLDELFMHQVGTLTPHRLVCQVQCSNCPLKFDAKLSLADAKLQKWCPRCSALHVVSLRPVFAHAASDVVAYIDSDNCAVVDVLPSDLLASCLDCSTEALVESTVPGRRSEQACFSCHTKLAVMTKRFVVTHLSTSNNGVVSKTSSAPATTKKTSKRPTETFVLGQPLPRNGVCEHYKHSFRWFRFQCCGKAFPCDVCHDSSDCPQANTGKIASKTVCGYCSKEQSSSVKECSCGNTMGKKVIKSSHWEGGQGCRDRSRMSANDKAKYRGVNKTESQKSKRVGQEGKARAQGHHRAHPETVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD17</accession>
    <name>A0A8K1CD17_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD17"/>
    <dbReference type="OrthoDB" id="127926at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="681" mass="75600" checksum="03EC7B94FEB8A2E2" modified="2022-08-03" version="1">MISFDTFIGSGHAESDSTDDDAALVKDGRRGENEGEVVDTPRGRRKNRIRHVANGRVQHLFQLLSLKNHTGDAKQALVQRLLNVTIVKELLLSKADQDQIASAANDAITEEILATVDMEDKRRKSISSGGTPNYEEFSSENRKTMIGTFVVGDMTQFSTYRVLELVDVLDSTTGGLVKRILLNIRRQRSGPQHAESEDLLETTEFCGFCVDYRGHNTRQHRCRICGALGQHRSQYCTQKPSTRPPTPSNRPPTPSNRPLTPSSNHPPTPSSNRPPTPSSRGRRRAAPTPPTPSPSRLTPDSSDKSYCTFCSTWGFHSTENHRCRNCSVRGEHRSRHCPRKASSEGYRWRGSPADSSVERKFCDLCGSLRGHSTEEHRCRICLKLGDHRSKNCPMHTPLSDYASPEAKNDVVVSRRGRTTPNGTLLRWHCSFCTKEVAHRSEEHICRICRATGLHRSGDCPSRRATPQSVLSYSVEKASKVGVRVLETIPLVLPASAAALVYESVDKVGDVDAILRRTLHRIGVWGGGSQTPITTPYLAQRAHSSIDGSATAAIVALPATQGVEGHGVYVLSYAEGRSMVPERILKYMRLLMHHEISTNAFSVVVRFDPRPSHWELQKPGMVTPRSLPSSPTMSEQLKKRMAKYTLSTLLGAREKLVKLVVAQKKLQEQHQQTQEANHEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDC2</accession>
    <name>A0A8K1CDC2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDC2"/>
    <dbReference type="OrthoDB" id="158652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="178" mass="18974" checksum="5D4DBC9BC5395247" modified="2022-08-03" version="1" fragment="single">VRYQAAPTTRSTVVYAFDTAVARPVRWMGALPAQKLEGSAGDTVARFGVPYPAVGVVPNRVDSVGLMAVGGKTCLVVDCKRSAKARGLCWRHGGSVICTIEGCTRGAKSRGLCWSHGGGTKCSEPTCDKTMISKGLCWTHGGGKRCLLDGCKRPASEKRQNFCPKHHAQVSQRGRKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDE1</accession>
    <name>A0A8K1CDE1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Barwin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW60994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDE1"/>
    <dbReference type="OrthoDB" id="147725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001153">
        <property type="entry name" value="Barwin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044301">
        <property type="entry name" value="PR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46351">
        <property type="entry name" value="WOUND-INDUCED PROTEIN WIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46351:SF3">
        <property type="entry name" value="WOUND-INDUCED PROTEIN WIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00967">
        <property type="entry name" value="Barwin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00602">
        <property type="entry name" value="BARWIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51174">
        <property type="entry name" value="BARWIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477900" description="Barwin domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Barwin" evidence="3">
        <location>
            <begin position="64"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="139" mass="15183" checksum="CCE400A5B8C070B7" modified="2022-08-03" version="1">MLRTLASIALVAALSTMAPAAVDAVTATYHDYNGVKPEQTFCNIQFKSNKRITAYANLGSDLQCGDCVEVTNSRTKSKLVVKVVDKGGNIFDLAQDAFDTLDTDKNGYAQGHMNIEYKKVPCTCEIKARALSAYNETEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE22</accession>
    <name>A0A8K1CE22_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE22"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05301">
        <property type="entry name" value="GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000026">
        <property type="entry name" value="Glyoxylate/hydroxypyruvate reductase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF257">
        <property type="entry name" value="GLYOXYLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="32"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="5">
        <location>
            <begin position="119"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="387" mass="42842" checksum="DADE91AD76844D7A" modified="2022-08-03" version="1">MSTKVFFSRRVPYALDRFRHLLKSSSSSIPVNIQCFDSEDQAIPRDEILRQVKGCSALFCLLTDRIDDELLDAAGPSLRVVSTMSVGYNHIDIAACEARGIRVGHTPGVLDVSTAETGVALTFAAKRRLVECVDSARNGEWGVWQPFQYCGTDVTGCTVGIIGLGRIGMTYARMMKFGFNCKIIYSGPNEKPEHVAALGGDVEYVDLDTLLAQSDIVSVHIPLNESTRASMNARRFAQMKDGAVFINTSRGEVVDQDALYQALKTKQIAAAGLDVTAPEPLPTDHALFTLPNCVILPHVGSATVKTRQAMADIAVQNLLAGKQTTLDFYARISQIARLSMSLYKCVCSPHDVRMTIQTLQKQFKDFKFRRYCFGMWRNQVSTWRSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE39</accession>
    <name>A0A8K1CE39_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE39"/>
    <dbReference type="OrthoDB" id="76153at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37473">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37473:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="158"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="423" mass="48703" checksum="7A6B9F2D7453E5F2" modified="2022-08-03" version="1">MEVAAADAQDLALFLSDEDEEETCDEPTETATEEDLGSEEPPSQDDNNDELSGMESVEQLQQQIVEQVQPWGHEFDSVEAILEQIRPNASDEASVALVTAHLQRLPSDVNIKTLIQLLGGLREEYVPKDAIMSIWFKILHPKKAKRAKSAGTMPILRSRLLESKRKQAECDLQLLQNRISLLQQEESRAWKKILQTKDRAQEILEIREANLKKQEAKSHLALERERQSRFVQKKQHSLKKESIIKKKHAAIQIISRKYQDVEIVKSESKRLKAEKEKQQMVEVERAREKREAIRRQEDALKQKRREEQRQHEQEIALRYMKKVIEEERKIKEHQRRVQAMEQQEKELIERLQGTQLIQQEAFSVLEQALLRAELRASAAQQHEQNVLLSSTSSTSVSASSLYGVDPLDRHASLSALTIGKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEP9</accession>
    <name>A0A8K1CEP9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEP9"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="228" mass="25856" checksum="0518C89378EDC354" modified="2022-08-03" version="1">MEDGRCELLSGAETYAIQLLLGVIAFATLWYKRHVERPRRTLQIWAMDVSKQAIGAAVSHFINLGVSIQLPPVTDECVWYFLNFISDCTLGMIVSLAFLRLQQEIAFAMNWTNIQESGEYGNPPSYRSWALQLVAWLMIIVFSKAIVVSVLIASSTPLGAFGEVLFHPIKGYPLAELFLVMVMCPSFLNVVQFWIQDSFLKRDVSILPAQYARFRHTFDESLQAKLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF44</accession>
    <name>A0A8K1CF44_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF44"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF9">
        <property type="entry name" value="L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="274" mass="29320" checksum="98326FC0B6613D1A" modified="2022-08-03" version="1">MASTTTPSSFTSSVFMTHISTATAILSIDGINFLIDPAFDSAGSEYPIGKVKLVRFDGPALQLHDLPPIDAILLSHEDHPDNLDPSGRTLLNGRRVLTTQAGAKNLAPRPGVQGLAPWETVELLAAGKTFRITATPCDHLPGGECIGFVVHTDSFGVDANGRPNVIYVSGDTVYMESVAQRLRAEYNVVLAVLNLGAAMVSLPTGPTMITMDGKQAVQLTREIEADVMIPLHYESWGHFAQGKDGIQEVFNGPDAKELKSSVAWLEPGVCTRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFP5</accession>
    <name>A0A8K1CFP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFP5"/>
    <dbReference type="OrthoDB" id="77288at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="3">
        <location>
            <begin position="300"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="3">
        <location>
            <begin position="610"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="302"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="612"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="743" mass="82451" checksum="72B7AFDF94CAAFBB" modified="2022-08-03" version="1">MSAMKMEFICEDNSEDAPRQTNANANAKLSALLNRASHGDSDVEMHDATERNGTDEQGAAPPRKKAKTEGEAVNEQAGAHADGDVNGLSDNENSEDEQVEYAPWEEVDLNPAVDLVNKVVRESLEAGKTYNKSITAKTSQLISGCDTVLLELKNLSDAREASRKQSSKQQGPQDGDCTCGVAMSILPLVGKSDSVVGAKQNEGQSKGGKTAQVDEIAEDQTDRVLFKIEASMERLRELAELIQATSMQGEANLVSKVTLADGVIGALNNAIQASAASATAAAIAQERGRTASMNMHGRLYSPLQVKKLQDWYYSYPRPLTDELTLMRTILNYRPFANPFIPGGLTIAHIRDWFKRRRYRERLRYVKLAVEAGRDPVAAEEEIDLRIEQRIEHLRMTVDPNELVKELDKVRAESSLYDSMITSFARPETLDSYVSASHALPSFADHLSAQNGGRVKRQRTQDSDLDDAIVVKIGTPTELIVMQNRIRSLLAMPRSATNTNALQQVIDILRSMEVSKEVRIQTGVVADLKKILKVYKKPTLLRNSTIALLESLGMSRRVIMDDNAHDEEPTMTDELSHPSGELSVKHESTSSSAGVTNLTSPVKISRGKKEKGKIQRPMKFSMKQVMALEAWFQQKYKPTQTEMEEYLDQLNSPPLRDEKQPVDVNMTQLRRWFNKRRCLRRPPFALMTQQDAAKDDIKATDEGKVGLEHDEAGGDEFGAEAHHHESADNTNDDSSDDDVSSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFQ1</accession>
    <name>A0A8K1CFQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFQ1"/>
    <dbReference type="OrthoDB" id="79475at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DZANK-type" evidence="2">
        <location>
            <begin position="293"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="538" mass="58457" checksum="96C41F50A7AB62F6" modified="2022-08-03" version="1">MGFCGECGFLLTPETAGRFCPECGAPVAANDHLEAHARREEADRKAMEARQRAESMQREATDAISVLEQQERARVEMEMEREESMRQARVDEERRAIEQQREEAARRREDAERSAREARERAEAMRVSAETAIHEFEAQQRAAAEREEARKQQELERKRQEQIQLAEAARARRENAEKTALEAQRHAEQLKEQALAAQRELERQERLRKQREAQREEARRLREEAERREENRRKAEEEARRAFEAKKQAEQLRLEAARLSSQTASLQALSLSSSSSSLSSLGSTSASAGADQCGNCSASLKPAQKFCLQCGTKRAGVAAPAPVAAPPAPAAAVAAPSSCTKCSATLKPSQKFCLQCGTRATVAEPVAAPARAAPAPAPVVAAAPSSCVSCSAALKPSQKFCLQCGTKVAVAAPVATLTPTSSFSSTSSFSSSTSHSFGASVQLPAPIPVLPSTGSASSLPLTKNCRSCGVECKYAAKFCVSCGFNFAKADDDEVARNLEAARLRAQAVKDKELQQRNQASMLASQAVRSYQPVYQSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGI5</accession>
    <name>A0A8K1CGI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGI5"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000081">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF16">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035428548" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="234"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="529" mass="60052" checksum="6F379D051C5794E6" modified="2022-08-03" version="1">MSMMTMRLTLVALVLCGLAFVHAWPRTQKELDQLPRWDYWQPVAGRPQFTGRFLASRPGMIHLKKQTFDVANLFDLDETVNNKLLYGSILLKPTVVTTAPLENPAVKAAFEFAIKAMKISSHGANLSPTPTLVKAVILPLYVTGDNGETEMVVLHEFQSTRRETEFFRSHVTLGTNFYLTIEDLSFQLRHQVGVGLDREHVHNLFQHTFAPLSPSATQTCDTSDCHAASPPRILSFNVWNTNPSGDVYGQSRRWDQYNKRIDHLMSFVKESRADIVGFQEVRYDGVLANKGQHSQVEHLAKRLPGFQFVYQAAMSYINDRSPYERIEEGPAIFSKYPIVETDYLLLSRDPNDPNDSHQRLCLHAVVDHPQWGWIDVYATHLSLSERSREQTMLEIWNYMQHGKGVTQVLLGDLNAEPDSRGIQFLRGDARLDGQTTDLKDAWLEKHMEAAPRSPDAHDRAHKFTFPSDNPIKRIDFILYRGKGAIKECEILAQAPTEDTKDFPTDVGMLNSQSPIYASDHRAVVAEFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGQ8</accession>
    <name>A0A8K1CGQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGQ8"/>
    <dbReference type="OrthoDB" id="68104at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.70">
        <property type="entry name" value="Hypothetical protein apc22750. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145_YbjQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068:SF2">
        <property type="entry name" value="UPF0145 PROTEIN SCO3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="UPF0145 PROTEIN YBJQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="YbjQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="18616" checksum="0582C89211DD5B19" modified="2022-08-03" version="1">MALRAAALRVRPAQWTARRSFATSADGTPTKLYFTTRDRIHGREVLEEYGMVSASAVRSKSVVSDMYVALAGLFGGEASSYTSLMNETMAEAVHRMQYAAQSLGATAVVNVRFDTNTTMNRLVFGMHCSVIAYGTAVRCRPASMHHHQPSSKATAQLHAATMAHMDQTNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGY8</accession>
    <name>A0A8K1CGY8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide exchange factor SIL1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGY8"/>
    <dbReference type="OrthoDB" id="448649at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457375" description="Nucleotide exchange factor SIL1" evidence="2">
        <location>
            <begin position="30"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="58534" checksum="8ECDB529D1167FAC" modified="2022-08-03" version="1">MRVRGRRYGVAVLALVLAVLSVLALCANAQESAKTQSNCGSDDGECRADAQQVVAVKATAPEFVATDEWQEVLPGQSVPPGLHIRLNFQTGKREAKLLSEDDNDQVADPNVITREVVVNSDASVTVETDITGEVNAAGVTTNPSSHAVVSVETEDKDAEDITVTEEIKSAPESKGAEPAQEGETPPAAEPNWNHEKIYEVLQALPEPPLVDGMDINEAHAKLSTPEFRRRIIKLWKKRQQELKDAIESMQDDAKYLAKILEQFQEAEKAGNTEEQLRVLEVLEWEVQDLDKTHVFNFIGGFNIITEYLNSTNLPVRAHAAWLVGTAVKNYKDGQDWAINAGAIPKLVNSLSLSVPSDDSTKSDEVYEVKKKALYALSSLVRFNERGQRLLLSLQGPDKLAQLFDNNHPRGVQLKAVLFVHDLLFEEPSASHTEGDEAALPQLHAIFRSSAWCNHVAEFLNTHGSRLQRHQAAEVMDAMKEQLPACSTEFAAKNVKSTIEKIKSTWSQDSSLEDDERRELQVPVDAVLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHM3</accession>
    <name>A0A8K1CHM3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHM3"/>
    <dbReference type="OrthoDB" id="181500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="112" mass="12691" checksum="D56C3C6B45880EB1" modified="2022-08-03" version="1">MSTEAVADDVHREKYAQLEELFRTTQQDCSELSDRHATVVQQLDRIRRENDYLLDQLSQYNASDFESDQSDFEGEDLLEKLTPAAPHGKAKVARKRVTTPKASPISKKPKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI62</accession>
    <name>A0A8K1CI62_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_002111</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI62"/>
    <dbReference type="OrthoDB" id="10257567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Cux N-terminal" evidence="14">
        <location>
            <begin position="38"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="13">
        <location>
            <begin position="460"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="103"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="450"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="536"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW63170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="703" mass="79166" checksum="D87B7B83580E541E" modified="2022-08-03" version="1">MEQVAGDKVMTEAAASAVGTAVASAPSSRGKNSGLSRNAIGTVLQYWKAFDLDSKRVMLDTQGGTMKTEKDNSLRSRKKLAETTKNFRKLPDADKVASVGGLLRAYQEEIDNLTRRAKYAENSFFTLYKGLYAAPDPVPSLESLNDMNKLGELEEENKKLQNELREYEIEFSSLKNQDITIRKLEEQVALMERNMDDVVHQKASERCKELEDQLTAKTLEFNQQRMDYERQLDQGRSDLREAFSRLDALQSELFEHKQRSGLAQSSFNAEIEAMSQEALMMQTLRLENSQLKKQLADLLSVAGDGSGGRTMLTSLTTTPPSDLSQKEATIVSLRQEVFRLKEAVTHLEDQAASDKSRYDDLLDQAKRARDDLSAQLAARPTMETFNEIQHQLRVLQQLEYNIVDEEGIQTAPGGSSSETDATQASTETEKILVSRVRRLEHTLQQRDLVIQEQSDELKRAQDALAQKEKAIAEQADLLRSLEETVAALESRRGGGDASRTDVGAEILLDAVDDQLTDRKAADGANGAGVAAESKMFEIVRGQRDRFRDRMKELQTEKNKIEELVNTYKSQVARLEHDNMQLYQKIRYVESYRGKGPSNMRVAPGSSMSDLEGGSATSSVTEVESRYKSMYEEKMNPFQQFNKLETQQRYTNLNTVDKILLNSAKLFLGHRITRNIAFGYILLLHFLVFATLYTFMHGCGISNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIR9</accession>
    <name>A0A8K1CIR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIR9"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="425" mass="46773" checksum="4090EF4D3F334692" modified="2022-08-03" version="1">MYAFLLDGDGSNRVYVLKVEDARAKEMQRHGELLDAVQRQLDGSRRNEKELLVMVAKLRADKCQHDAEMAALRAKTKQTEDSAQASDQRQRLVNEDWRERIDGKDRVIAELKATVERLQGAVADGAVQQSVSRTQVEGLERDNQRLHAEHAELEKRYEVLGLILDRDHIYSEWIYPKSLISPWPSTSRECAITCSRLVLLHPRSEMTTSSPKKRQPLFDSPSKYGVHHAISAFTPTEERFKWQSTSNPTDALYALPTSIGTGSKKSFGTSTREDWDPSRKRSDDCAGPGSYKSVGSCGRQPSSLCRNSSVTAFENASRSSLHSDATPSPGPIYDLATTVGTAPSPKFGTAKRMPLNGKSEGPGPNLMLPTAFKEHAQGVAPTFGTEKRMRPGAGSGGSAPGPIYDLTTTGFRTGSVITFSKAKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIV6</accession>
    <name>A0A8K1CIV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIV6"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20104">
        <property type="entry name" value="MBT_PHF20L1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="78"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="384" mass="44107" checksum="CABB9DE3DE846C70" modified="2022-08-03" version="1">MSNDGERPEIPMELGLRVDILDNEGIWNTGRIVDVSRDDDDMVEVKYDGWGDEYNEWVSLAERRLAPLHMFTMVKKCWAKLTKWPWWPAFVVLRAPTCKTAAAALEQETKLYVEFFDSYDVEKRSRCWMQKKNIVSFQEGFDERASKNIGKNFPLFVEGTQRAIAGGSPVLFTGHGTLPIEFSSKYAAPLFQKKLDLVDNDEERWYDAYRVFSDRYKVLYGYEYAVDSVSKVLAVRNAKTGSGKAASGKRVQRDDNDEEDEDEDDDVEIIEDVVAKNNVKKSVKTAPAPARRARDYPAKQPPQSVDDDDMEDAEESEEKEEEPEEDAASDEDDEEEEEDDEEDEDPESPNGRRSARLTKKRKQEEEDTLAARRTTRARRTKGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ93</accession>
    <name>A0A8K1CJ93_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014186</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000904">
        <property type="entry name" value="ABC transporter A family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000298">
        <property type="entry name" value="ATP-binding cassette sub-family A member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="505"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="595"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1103"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1312"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1365"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1406"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1440"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1518"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="730"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1580"/>
            <end position="1813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1983" mass="218664" checksum="099ED50701A00DC6" modified="2022-08-03" version="1">MLASLSRSESTPIMTAPIAINDKGSTPLSSRRTTWIHVKTLLSKNGLLKRRHAVATLLEVAIPCIFILLLGVLKKQTANVNVPAGWSDDSDHGTSYNFFDPTGSTIAWVPTPLPRFYMHEGSMSGLLLSLGSQSVFDGVRLDELSASNLAQCTQSVAVQGYISTNQSSPYKVPDACAEKVAPYKIGVAPDTAFTRDYFLKTMDQWYPRIKISNMTDDGVEIPSFRDSVEFFTTARDLEDYVKGKEYGEGALHPRLYGAIVFDKIPSDRNIGKFESIEYTIRMNSTLGEDGVLGVIPRTNDGPPEVSALRKALKGDYYSRYAVTGFMTLQTLVTRFVTCMPKWDASKKTTTGECQRPQATAISSDDLDDRLLSSLNDDARIQFALSALLSGNGTSMVFNISGTPMFPSSDVSFTELLAGSSPSVREFLLKPLRQAPQPYLGGAVAPFPIESYVGSPFYDQVKDVFALVFILAYLYCVSRVLVVFIQEKESRIREYLKILGVKEKAIIISWYITYIAILFVGSILQALAGLAGLFENSSVIVIFLFFFLFGLSMLSFGFLVSTLFSKARTGAFVGMILFILMYFVSSIFTPQTAENAKTIGCLLSPVALSLGINVVANLESTGAGITFSNLSIQSENFRFNTALIFFVIDSILYTALGLYFEKVIPKDYGTTLKWYFPVSPSYWRGRRAGRIPQKEEATYLDAPDSVIVDVNPAFEPVNAELREQERNGDVLSVQRIRKVFPVPGGEKVAVKGLNLVMYKDQITCLLGHNGAGKTTLISMLTGMIAPTSGDATFRGLKLTEDMDEIRESLGICFQHDVLFADLTVEEHLIMFGRIKGYAGDELQQVVTRQITEVGLTEKRGVKSSELSGGMKRKLSVAVSLLGDSSLVFLDEPTSGMDPYSRRSTWEILLNNRNDRVMVLTTHFMDEADILGDRIAIMSEGELRCCGSSLFLKNRYGAGYNLTLVKDDQACNDSEVINFITSYVPNAQVLSNVGSEIAFQLPLDSSSEFAGMFAELDANLSKLALLSYGVSVTTLEEVFIKVAEAGDEDNQHTLTKDARVVDPVPVPSPTNSSTSSSFTTSGLFGAHLHALLLKRFRVAKRDRKMLVFSMILPVLLLLAGLLFLRASNLAQSDSLLALTTDAFESKDQSPTPYFCQADDDKWCSAMMSPKVFTGALPEQLSSDVMKQYDSESPTVFGVKYTDPKINTSDATGYGLRLGEVLYKRGYGKDQDFVTSQYGAYLVHAEGDRNIIGYNVFTNTTSTHGAAIFKALMDQAIYRFFASNTSSDASANVDLKVNNHPLPLSASTKALYTSFLSFASCLFIVIAFAFFPASIVVFLVKERESSHNAKHQQLVSGVSLPAFWLSNYMWDMVIYMVPFIAAIVLIQAFDISSFTGNECVTCASGTFPAVVLLFLLFGLAICPFTYCMSYLFSDHASAQTYTIMINLVLGVVLTVLSFILDKIESTEDANKVLVFLWRLSPLFNLGNGLLRLTRHEIRSIEGGVRDKPSPYSGEMMGYEMLYLFLSAIAYSVLAVGIDYALTFPRVKNLTNNGRSVDDEQYEEDEDVIKEAHRVQSGPVDDVVVLKNLRKVYKGGKVAVRNLTFGLKKGECFGFLGINGAGKTTTMKMLTGDVIPSSGTATLSGFDILTQQIEVRRQIGYCPQFDALFELLTVREHLELFARIKGVSRAALDEVVSEKIQQLNLASFENKLAGSLSGGNKRKLSVAIAMIGNPQIIFLDEPSTGMDPVSRRFMWDVIAGISTRGKSSTVVLTTHSMEESEALCSRVSIMVGGRLRCLGSVQHLKSRFGDGLVFDVKMTAPSHEELQEVVDRVMFDANSFVSSDEIADKCRIFGNAELASRVSADHPTGYSLAAALERDGFIRGPAFCSWCVEETRFDALHRFLGESFGDDNILVMERQNDFCRFKLRGSNAQLRLSTVFDRVERVKSKMHIREYSVSQTTLEQIFNQFAGQQSEEQGVARGMMQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJK6</accession>
    <name>A0A8K1CJK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002343</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJK6"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15777">
        <property type="entry name" value="CRBN_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034750">
        <property type="entry name" value="CULT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51788">
        <property type="entry name" value="CULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418795" description="MRH domain-containing protein" evidence="5">
        <location>
            <begin position="26"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="CULT" evidence="6">
        <location>
            <begin position="51"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="7">
        <location>
            <begin position="194"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42065" checksum="1175DE005A29C6E8" modified="2022-08-03" version="1">MRRQTMHVWLCVAVVWVALWAAVEAHETGASVPVPTKTTEEKAVVTQEHTGPFVRCRMCGAKVARKSDYVPLHDTSKSVASRPSSLFGDDGEVHTFVNPSRVEMEVVAFKHAIGIESEAFTNKATFFDNYNWRDLRCNSCNRHIGWKFHHDELQQCIHTKIMEAVSAKSQEELKAASAEEMAKKKELVRRELEGKCVTASAGWWTYEVCYKKEVRQYHEEQDGTRPSDWSMGVYVGDDRKPGDTMSPMSSEIAQYFTGGQHCDENGELRSSKVVYQCCKSKPKAPTIDNVEEPSLCTYMITVCVPSLCDKTDKTKKSSTYDYAQIASTCEKEFEHSHEASETPSNFAALRWSTVVSEDSSELEWARNLQIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK40</accession>
    <name>A0A8K1CK40_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK40"/>
    <dbReference type="OrthoDB" id="155125at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="685"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="749"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="834"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1027" mass="115324" checksum="7CBFF6E14E599CF5" modified="2022-08-03" version="1">MDEKSKKRPHDILASLDAAFASVESKPASKYTSKAALQANAAASQQAYQHKRKRRNKSSGTQQSNGNEKKGDDSKPNQAAVSKDKDRQEPVQSVAKYDPHYGRLDVEVLQVGLKNCSLVRLASMRKPNVLNATLRQYIEALTTNQNTGAATDKLKNKVMQFDNPIRTTDAAKRAQNETQAQSAKLLSARQRRKLGLHLVSTPIKYSEAQVLCEIWRRYARDILQDDFGQVKDEAVRSARIQAKLKTLDLSGCPIEVVKSRNPCNIGIEGIIISEKAHIVQVCVRESGKVISLAVFTYALLVTDILRSGPTLNSLAFPRIEPNVFATEGPEVLPTRVVSRSFDRTAALQAAPVYSSSTDPDGTKISEFKYAPSSYGMRSIHALRPEDMSWPSCLTNTEYDEECNLSHLSPETVYHMLNDLVETVRANSVNTSCYKTDFKDVLDSAPQPGDLTTKTVAELLRTFLATFPQRVRFVARAKTRWISGAGNFLSHYLLDHKYWMGVWATHFDDFDNTKPGIQICIDDLDRPLLCEKTWADFGRLKPQGTVDKLWDDITSRAVALQKANPTLTLDMTIIEAESDPLTLLGGAVVIAHKIFNVVVLYRQQLCSPGTKDCELQTIQEVRYEGRVLYTDVIEWNYITGLLRYGAQAYMIARLVCLLVGCYRIAPRAVGSGAQRGVKRLQTAFRLFFAMPCQVVVYGSFIPVLAYALAHIVDGVVLYHIDDGSLSSPSHFFACSFAEMIRLLAVRTRNVWFAAFIVRVIVFINTSGNWTPAMGVTAFKGYLLPYLSTAAIAFVITNPSFRDARVLEANEVEPSPTFMLIRAETLDSWKMNAGGVYTDIIMLGLACFCYLGARILFHVIRRLVRGKSSNGEEPNVLSWWPTSLCWTDCDVPYSAGYLWDPSCLVVGWENDMFATMLGSEPPPVRRECRISEGILLKTTTKYVLSEIPTRVALMNVLFLSDPWNYMTLRLGFSHIHLYHLEQDGVVRYVLHPYSRPRFLREFEFKPEEVLLEKTLNAAEVDWDHLVLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKM1</accession>
    <name>A0A8K1CKM1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin-F</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cyclin-dependent kinase 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Poli38472_009157</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Perinuclear region</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKM1"/>
    <dbReference type="OrthoDB" id="62452at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07829">
        <property type="entry name" value="STKc_CDK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000574">
        <property type="entry name" value="Cell division related protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="308"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="TMW64990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="890" mass="99340" checksum="246D3CA0999CEA71" modified="2022-08-03" version="1">MSTSPSSQPREASGASERPQLAPPLASLSIPSTGAESTPSKKRKHASSSGATSASSSSAVPALSVTSPSLPSNIATTSSGKPPVGIRELRGPGGGGENPILVALGSTPRGTTSQFAGFPDPDVLELGATAHSKRSSLESMTTTASQAPAVAQAGAASLKRKREEHEEDDETVKTEFVAYAREHVHNQEAGEEGFSIDPSDRAVEHRANKLVRREILIASPAANDEDEWEGSATEAPMDDSMVESKPAEHIDLQPVDMILHIFSFLVSSEDFPNMGLVSRRWRELTSRRSLCRALPSILPDGSVNWLNFQNLGIKNKGTEGTCFKCHQRSTGRILAMKKARVFPKGEGVPYYMLRELAVLKGIKHDHIATLEMISLARDELHVFFPFVDKTLHEIINPTGDPSGGRVLSERVIRRLLHQLLDAIAYCHRRGVLHRNLKPKHLLIKTADLDTLEDAVLQISDFALVRATGIPKRTYTMEVVTLWYRPPEILMGVRGYSSAVDIWSVGCIFAEMAQGKPLFTGISEIDQLFQIFSKLSTPTSESWPGFRSLPNYHFEFPNWRRRPLNRLFPNISDLGIDLLSKLLTYNPDHRITAEDALRHPYFSEAAPSIEALTPTIPMDQMAYVMNRLRSSTIPEHVELFHSHLRQTERESWKEIKYLSRQKTLRPAHRSMLVDWLIEVVDVFEMCLRTAFLAVNYTDRFLDIVMVKKTRFQLLGATCLHVASKCEDVSYIGVEDLAMCADNVYTSAEVLKMEEKLLNTLNFTLSIPTALDFLNIYERMIPPIQKKTSMLAHYLLELALQEYQFLKFLPSVVATCCLSMAMYTVDGFPMSEDLADACQYRWMDLRECMSELQALYSSSPSNNLAVIKKRYSKAERCQVATIMPPATFNMAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKW1</accession>
    <name>A0A8K1CKW1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome assembly protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RSA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKW1"/>
    <dbReference type="OrthoDB" id="69550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051898">
        <property type="entry name" value="Ribosome_Assembly_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028217">
        <property type="entry name" value="Rsa3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127:SF1">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14615">
        <property type="entry name" value="Rsa3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome-assembly protein 3 C-terminal" evidence="8">
        <location>
            <begin position="197"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="260" mass="28173" checksum="DF2FB8234953A4DA" modified="2022-08-03" version="1">MVKSGSARRQESAAAATQRARIVHEYDKIIAEFGEDPFRPGAVSQRADGLGKVMEEIGASDPKRRHELLKQVTEKSVRCAELIEKALSAADKFKAMDAKLKTAMDEYEMGVDAVGDDDEDEDVDMDDEEGAATAIMLGDLITASEELQQAGKQLAQVGIVAKSTQASRALLSSTDQTLNAALGGITPAAEAAINDEFRDLYAEEFTSAFGDDLDRFRQEDRFESKDVNYLISCIHAGGDIFTPLQKKLFVESARGSNGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL79</accession>
    <name>A0A8K1CL79_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL79"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="343" mass="36613" checksum="80F4386CC9D8A926" modified="2022-08-03" version="1">MADSEELCCGCADLASEDEYNLGLHIGAIFILFAVSTAGTALPVLSKKVPMLAAKSMVMQWLMVFGFGVVIATGFIHMMNEGIEMLSNPCLGEVVENYESLGMVIVLGTIVVMHLIECESAVFFAGQGSPHGHGHGHGHTHGHIHDVHHTPLPVTTSVSSPALTDDEHPYHDKLMLAPTSSPDAKRKVAAVLFEVGVIFHSVVVGVDLGVTASTEFQTLLAAMCFHQFFEGIAISSSMLGAIESFKNVLLMNLAFAVTTPLGMVVGIGIRSTYSSTSVTALWVQGVLNCVAGGILLYTGLVELLTYHMTTNPEFLQRSALQRFALYFACWLGAGAMALIGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC0</accession>
    <name>A0A8K1CLC0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC0"/>
    <dbReference type="OrthoDB" id="164177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="39519" checksum="82BC672989E3BD8E" modified="2022-08-03" version="1">MAMPSAAPPSLDERLPLFSTKDKELRAHKLENRNGVLFAVPAHSSVLLKILAPKSHSYEERDLRWLHLLQAVAAVPSRKVETIAKLVQQAMQMVPSPTYRRTLEQMLRGLLDVLTKTDSTLSFSTQALLALRVKDQVATFLRQWIQDPIEGFVLRKEHVVGGMRMDDLVATPVGAGYLRAFRREDQFCIVVFPWGHGFVRLSTIERVEDAVVQQRAKRRHNEYLALEHQHLYEQVESLLENYPAESTLNYGMNGDNPDGVNVAEYEQLLASLQEEHYDTEVLQRDLSFVRRVQALATKLKRQRTQQPADEDMEEEEEGEEEEEDEGNVAEAAPAEAKDDDDDIEMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLH1</accession>
    <name>A0A8K1CLH1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLH1"/>
    <dbReference type="OrthoDB" id="66163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="470" mass="53916" checksum="39040CE9B5A81172" modified="2022-08-03" version="1">MLQRAYPNSTVEYLILEETGTKKLEALTFQGREHGQLVIFSRIRDCSEEICQTVAVDDYRYEIASGVRDTKSWYKVVATFRVLGQTDLQEASVFRKLFVSLRTVTLIPSQVVVYGSLFPIVCYVLAHLIDGRFAQEILATEYISTQGAVYNFNFERYLRINAIAMRSVWKVAFLCHILVIIHTRRSWTPNRGVLGVPEFFLSLIIVPTIFAQFRVLSGRDTRILEMEEVIDFPRQIELQSSIFFSKHNFIGSLLVGGSSIDIKCMLCGFVLLCAVHVVVNSVHVLFPRWQPFQMVMMSRTKTPCTAGTLWQPNGLVVSWDGTIFVNPARRRLTSFTVRSLTSHVSLMMHGMVARRLTKMPPQSQSALKRFASGTFKFRGASKVAEINRLDAMIYIMNLAIMSDPVTLFQLRVISRQQVGVYESRHTRRRFLLPYPLHEMGGNFSIDWNDLRLVIVMNTRELQWWVLLQCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CML7</accession>
    <name>A0A8K1CML7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008068</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CML7"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035426606" description="subtilisin" evidence="10">
        <location>
            <begin position="20"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="12">
        <location>
            <begin position="36"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="164"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="450" mass="47613" checksum="D342260BAAC2BE8D" modified="2022-08-03" version="1">MLRLQSAALSLLTVTGTLALEATKSRCHTQDRLDVIITMKQRTEPIVDSITEKVFSCNSDRVKAIKDGLETLAQSSQTGVLGLLGESPIHYTRSESYWITNQVYAANATQELVEQLSNHPDVASVAPEQVFNIEAISAPPSTNSTQWGVNKINTSAVWTSGNMGEGVIVGIIDTGVRATHVAIKNNWRSTYGWFDPLNKTLGSTPYDALSHGTHVAGVIAGNNGIGVAPNTQWIMCKGCRSDGCFTSDLLACFQFMTCPTRPNGSRADCSQMPRVVSNSWGGGQGLTIFDRAINLWRKAGIIPVFAAGNTGPNCGTVHSPGDNANVITVGSSDPLDTVSSFSARGPTVKGVVKPDIIAPGWAIKSSCSGSDTEYCTKYGTSMAAPHVAGAIALYLSAKPSATYNQVKLAFQKTAVNVTTPTGLSCGGTNDSMIPNNQFGYGRLDIGKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMS2</accession>
    <name>A0A8K1CMS2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridine kinase</fullName>
            <ecNumber evidence="5">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004266</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMS2"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="8">
        <location>
            <begin position="88"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="310" mass="34818" checksum="20BF793EC7EBBA13" modified="2022-08-03" version="1">MLKFASSTVANVMLVSGMLLAAAVVMHYRTTKQRRGNPLNKNATADARELELVQDIVYINNAVTPTNQFRFHHRRQPMINDEGNQILVVGVCGGSGSGKTTLSRAIIEEFGADRVTYLSHDYYYKDLNHLTMDERAEHNFDHPDSLETDLMVRHVRELRAGKTVQIPVYDFATHSRCKETVEMKPNSVILIEGILIFADKELANLMDIKIFVETSADIRLVRRLRRDIEERGRSAESVMNQYMKTVRPMHMMFVESSKRVADIIIPHGVNSVALDMIISRLHSFTSSASSTGSSASNSADEGDDEESVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP50</accession>
    <name>A0A8K1CP50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ataxin-10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003956</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP50"/>
    <dbReference type="OrthoDB" id="379794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="4">
        <location>
            <begin position="458"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="565" mass="63207" checksum="689FDE169763F9A6" modified="2022-08-03" version="1">MIMATALTSGELEALALQCRDAGFREGLASAELLWQQVQVTLQDGLSALDANITRSGTGTSSSEAQHDSGVEDEDDGLSYSFEVKKDASLDELSASSTTIHVHNTSAAMERVEQITSALRFLRNACAASPLNQDACREHQLLKLAHDIVMRGCIWSDVEDDALQQAVVLQSQVALQFSVNAITGRIASQNAVWELYFPDDFQKLLVECHEHRKIVAFTAALILNCVNTPCNGDMNQRRTDLVCARNLIITLLQRCLTRPTNSYERQAPVDDHDPAFEWICLLFRVLFESGFSKELYNAVGAHLLSRLWSRVTPEQLILLRMFTMWITSRRSKPRTPDDKQTDTPVDLVVEDAEERFIIFEFIKNTWVYITSLEEEDRPEEADATRRVMWMEFENEAKLLLLDVMGELTLAPSSSQVAEEALRSLLSELQRVWALRPLGGLAGKSPSSSQDAGKEPFGYRSAIIRVVGNMCHRQESHQNLVREEGYLPLFLNHCNIDEPNPLLREWSLVALRNLCEGNEANQAYITALRPQGLDSSNVNLSNVNVEASLSDDGKVRVTQKPGPSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ66</accession>
    <name>A0A8K1CQ66_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_007448</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ66"/>
    <dbReference type="OrthoDB" id="10259236at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003214">
        <property type="entry name" value="PRK04179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="92" mass="10519" checksum="FE593C2C48BBAE72" modified="2022-08-03" version="1">MTKGTQSFGKRHNKTHTICRRCGKSSYHVQKSQCASCGYPAAKMRKFNWSQKALRRRTQGTGRMRYLKNVSRRFKNGFREGSSAVSKKAATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQC5</accession>
    <name>A0A8K1CQC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)(+) transhydrogenase (Si-specific)</fullName>
            <ecNumber evidence="4">1.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NAD(P)(+) transhydrogenase [B-specific]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_012425</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="12">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQC5"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003957">
        <property type="term" value="F:NAD(P)+ transhydrogenase (Si-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003585">
        <property type="entry name" value="PRK05249.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF93">
        <property type="entry name" value="SOLUBLE PYRIDINE NUCLEOTIDE TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="29"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="379"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="209"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW67309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="54569" checksum="0BD3A079D39B946F" modified="2022-08-03" version="1">MMSTTWLRGVTQRRARAFATAIKPQVAQYDLVVIGSGPSATQCALESAKQGKRVAVVDKNTSVGGVCVHTGTIPSKTFREAVLHLSGYRHHGFYGKSYSMKNVTIDDILYRVKRVVDSEVDVIRAQLKAARVDLIAGFARFESEHEISIVNDGNEESVSRLQADKFLIACGTRPAHNPNVPIDGKVIFDSDQILQGGIRELPRSLVVVGAGVIGMEYASMLNVVPGHKVTVIDGRSEILSFCDDETISMLKYEMRNKGARFLLGETIDRVEKTENGVKVFLKSGKVTTADALLYTVGRQASTDGLNLEAVGLERNARGLLTVNDATYQTDKPHIYAVGDCIGAPALASTSMEQGRLAACHMWEGTTDLVTSQLENGNYPYGIYTIPEISMVGKTEQQLTKENVNYEIGIAKYSELAKGQMSGGTSGGMLKILFDPDSLKLYGVHAIGEGATEIIHIGQVAIAMGCSLAYFRDAVFNYPTLAEAYRVAALNGLGRLSKDLEIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQS1</accession>
    <name>A0A8K1CQS1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQS1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="30119" checksum="067BFDD1337263EA" modified="2022-08-03" version="1">MHVGPLWPWRWRGIGKMVLLRRLVAVEPVWTLATYYLTYDDTVTLYIAALEADELQTVVRSLEYEVETVNFSGKDRQLVLHCAAAHGCVHAVKKLMRDAQGSTGKKLHRHMRQYVPSTSNTRTKTMQWLNTFRPYLYPEDIMYTAAARGDMESVEWLHTTCKYKKHVAMESAVSKGHLSIAQWLYEHVEKTLVRDFTPAREWESIRMLVPLGDRGMMNWIARVPGRITRSAPFVKFAYKCSVANALRGRTAGSSENIEGNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQT6</accession>
    <name>A0A8K1CQT6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_007586</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101590at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000528">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="523"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="556"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1107"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1143"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1182"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1221"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1250"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1344"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="74"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="771"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="725"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1374" mass="152451" checksum="3C25E19F914F1880" modified="2022-08-03" version="1">MNELRQPLKPTIGHASAKDLMAHGPEALHAHVSNQLETALGRAMHQMEVRFHDISVSADVVMASSKSTTNELPTIANSVRKSVGGIFAKKHKITKHILKNVSGVFKPGTMTLILGQPGSGKSSLMKILSGRFPMSGHVQLSGDVTYNGATTDEMRKRLPQFVSYVTQRDTHFPTLTVKETLQFAHQFNGGVHFSKRLTSTLSKTAPEETKAAVEAVQQLSEHYTDVVIQQLGLENCQDTVVGDAMLRGVSGGERKRVTTGEMQFGSSLVTFMDEISTGLDSAATFDIIKTQRSVAKNLRKTVVIALLQPSPEVFALFDDVLILNDGEVMYHGPRDQVESYFADLGFVCPPERDVADFLLDLGTRQQHRYEVTRTDASQLPRKASEYASIFRQSRIYNDMIEYVNGPHDPVLLEDKKELFELVSEFHQSFWAGTQTLIRRDLRMLSRNPGFFVVHVFLLTFIAFLNSSLFWQFDPTDSQVVLGMVFVPVQFLAFTQSAHISVFKAERDIFYRQRGANFFRTSSYVLSHLICQIPLSLVEAIVVGSITYWVAGFVPTAAGYFVFLLVLFLISMIFTAIFFFLVAISPDLNITDPVSLVGLLICALYSGFLLPKDQIPDCFVWVYWLNPVAWGIHTVGIAQYRNDHFDVCEYNAVDYCKQYGMKMGEYMLRLFSFDPDQAWLGYGILFLAGGTLLFMALGALVLEYIRYESPHHTMLIGEDLSTSTLSTSNSESGSGSGSGLESSTEYGLMSTPRREANIDLPRSSRCATPITIAFRDLYYAVPNPTNPKEDLELLKGINGFALPGKMTALMGSSGAGKTTLMDVIAGRKTGGKIRGQILFNGHPATDLATRRSTGYCEQMDIHSDASTFREALTFSAFLRQDSSVPDSAKYDSVEECLDLLDLRPIADQIIRGSSVEQMKRLTIGVELAAQPSVLFLDEPTSGLDARSAKLVMEGVRKVADTGRTIVCTIHQPSTEVFMLFDSLLLLKRGGQTVYFGDLGDRAGELISYFEKVPGVSPIEEGYNPGTWMLEVIGAGVGNTANEDIDFVEVFNASEKALQLEENLSREGVGRPSPLIGAVVYDSKRAASEWTQAKFVTKRFLNVYWRTPMYTLTVLLVQFFFGLASGLVAVSADYGTYKGINAGEGMIYMSTVFVCVVIFQGLIPLAGQDRASFYRERASQTYSAFWYFVGTTVAEIPFVLTSVILFMIPYFPIAGFSGASTFFLYWFVLCLQVLSFAYLGQLLAYALPSTELAMITSVWLIALFFQNMGFSPPRAQIPSGWKWFNEIDPARFAFATLTSIVFGDCPSKDSDAIGCRVLTDLPPTLPSELSVKQYLETVFEAKHDDIGINILYIVLAIIVFRLAALWAMRFVNHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR15</accession>
    <name>A0A8K1CR15_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007632</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR15"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="102"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="418"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="739"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW67960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="993" mass="109824" checksum="F763C6675D181E76" modified="2022-08-03" version="1">MSASVVLLWGMPVFVSIASFGVYSVVLHRELTPAIVFTSLSLFQMIQAPLRNFPSVFTRLIQSKIALERVAKFLDMSEINSDNIISIEDASADEYIKKNVIVSVENATFGWDESSMVLRDVNLEIKPGEFYVVHGTVGCGKSSLCSALLGEMIKKSGQVYVGGTVAYCSQQAWIQNMTVRENILFGKPYDRKKYEKVLDACALTKDLASLASGDQTEIGERGVNVSGGQKARIALARACYSDASIYILDSPLSAVDAIVQNEIFNKCLLGLLRHKTIILVTHNPEIIASEYITHTVTIDETGKLVETRKIQTRPVYDSAVTPLAAHAYVKRTFENEPDVESPGTMDEPTNEDTVEVLQELALASPFKEDKAKSFGDTEAESKEAVRLIAEEKRSEGRVGWHVFQAYYNAIGGLPVVTIILLSQVLWQVLQIASDFWLGSWSNDSTAEASDVASTEYRLGVYSALGLASALMVAVRTLTLAYFSLRAAKNLFDRMTNALMHAPMRFFDVNPIGRILTRYGSDVSTVDTSISLTFSTLLSRLFSVGASAITAAVVIQWKGLLLIPVVYLYYQIGAFYNQPARELQRLLQTARASPLNHLSESLDGAPVLRAFGSDQVTRFVAKNFERVDNAHKIWYAKLCVSQWFSLRIQLLGSLLVLVVTSSLVLLHNELSPAVIGIAFSYALKVSQNLESIVQSLTRIETIMVSPERLQEYIEIPQEASHRIPSMDPPKTAHWPNEGSIEFDQVSFRYKEGDRLVLQNMSLKIEGGEKIGIVGRTGAGKSSLTMALFRINELASGSVSIDGVNVSTIGLKTLREKLSIIPQNPVLFKGTLRSYLDPFGEFSDDELWSCIRKVGLGDRISNEEKKLECPVEENGENFSVGERQMLCMARALSRHSRIVIFDEATAAIDHETDQKLQRVIREAFEQSTVLTIAHRLDTILDADRILVLEGGRVVEFASPAELVKKGSGHFFELMQEGGYLEKFLSGSPTHSAHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRE1</accession>
    <name>A0A8K1CRE1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007536</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRE1"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="285" mass="30412" checksum="571EEDA8EBD7054C" modified="2022-08-03" version="1">MAPSTDNKVWLITGCSSGFGRELAIAARKRGDYVIATARKVETLMGLQDLGCQAVALDVTADDATVNDAVSRANAFYGRIDILVNNAGYTANGAVEEASNEDIQHIFDTNVFGLLRVQRAVLPYMREKRSGTIANIGSGAGYGTYPACGIYSATKFAVAGLTQALRMEVADLGIEVTVIEPGMFRTNIVGAGTLFKNSIPDYAPVTDFFKNIVSDGTADMPGSDPVKGAQAIVEALTHTGRCEGRALPNRLPLGGDVFDLMQNVLTTGQKELNDWKDFMDPKAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRM0</accession>
    <name>A0A8K1CRM0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LRRK2 ANK repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRM0"/>
    <dbReference type="OrthoDB" id="43922at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056593">
        <property type="entry name" value="ANK_LRRK2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF15">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23745">
        <property type="entry name" value="ANK_LRRK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="LRRK2 ANK repeat" evidence="5">
        <location>
            <begin position="164"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="390" mass="44242" checksum="AAD07C25AEB28F4D" modified="2022-08-03" version="1">MEEKAATQEEEEEAEEEEEEEEEEEEEEEGEEEEEEGDALSTKQAKAGGSRGSAKVLAVNGGGMALIKRPERPPDFDGQTLTQQKRIGHAWESGPRIDVLHYKYVQEDYTRRQAAVDQLRERMHKKSRPGYELRVQRKWTCKTVAGLLLRRHFSWMPCIIASMADAAWDGDILLMHSLLLLRGDVNASDKNGQLILNICIQQQHEPIVRLLLDRGADFNRQDEDTLMTPLNNSIIMGNKALTRRLLKRGADVNLADGEGLSPLIWAAIRGYLEVVAQLLEGGADVNHQDFFGWTALHIACFKGYVDLVEYLLVNANAKWEIEDVNGFTPFMFARIAGNDDIVRKLDEFIIKVANGKKRRWGKSKKKKKRRRPKVDLTKVSPKKLLASSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS47</accession>
    <name>A0A8K1CS47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_011281</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14890">
        <property type="entry name" value="MYSc_Myo29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="3230"/>
            <end position="3251"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="13">
        <location>
            <begin position="40"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="11">
        <location>
            <begin position="927"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1241"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1308"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1403"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1470"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1592"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1659"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="1941"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2008"/>
            <end position="2065"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2110"/>
            <end position="2169"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2296"/>
            <end position="2354"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2363"/>
            <end position="2419"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2556"/>
            <end position="2617"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2688"/>
            <end position="2746"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2755"/>
            <end position="2815"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="2855"/>
            <end position="2910"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="14">
        <location>
            <begin position="3057"/>
            <end position="3155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="611"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="7">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1061"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="1120"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="1218"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="1555"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2634"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="3161"/>
            <end position="3222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="916"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1067"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1079"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1122"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1228"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1558"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="2653"/>
            <end position="2664"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW67661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3255" mass="354637" checksum="13B337F65BEED129" modified="2022-08-03" version="1">MRRGGAANAQGASRKDRLMRAKMKKKQQEEENDPSGGASATAEDILQMSDLSEQSLLDNLRRRYEKDMIYTYVGPILIAINPYKDLGSAYAENTMTLYYSKPLGALPPHVFALADHAYTQLIQGGALDPANQSIIISGESGAGKTETTKIIMQYLARATSYHGHVQNGGQNPTAGVSRALGKLEERVLETNPLLESFGNAKTLRNDNSSRFGKFIEIQFDHHGKIVGAEIMNFLLEKTRIVSQSIGERNYHIFYQLLAGADEQLREKLQLKTPHDYEYLRKSQCFKLPSADDAEEFATTKHCMSTIGINEERQERVFDLLAAVLNLGNLQFGMENETCITVGDNADQMLELIAGFLRVSTEALKSALLTRHLYVGGKVIVQQQNVDQVRDKRDALAKAIYSSLFLWLVSELNRTISKPDDKWGFIGVLDIYGFEKFDWNTFEQLCINYANEKLQRHFNQHMLEVEQEEYTKEGIDWKHIDFQDNQQCLDLIEGKPFGKPGIFIGLDDVWRLKGEEANRKFVAILHASFGRDPSGSANTSKTQHDSYVHPKMDATLRFGIKHYAGEVVYDASGFNDKNNESLNDDMKELIRQSKSDWVREIFDLSVQSMESIPGNTKRADPMALSRRPTDLASPTTKNGGGKSRNLREVSVGTQFRFQLQELMSKISLANPRYVRCIKPNEHKKPREMNDQDCARQLRYSGMMEAIQIRQRGFALREDHDVFFYDYQALAPEAESIQELIVQISSMLGAGKEEWQLGKTKVFLKRGMAFKLRKLQTLRGKAAARMLQKWCRNLKRKAAVIVLQAKCRQFIAKRRVQRMRKAALKVRGYLRMRVDKKKFEIALAEYRYKVEKAIVIQKIARGYNVRKKNILQPFADMGPKELDEKIAELEKAIGEAAKSKNFELCANLQKDLEFVVEARKKVRTAKELDAEIQRLNKEMDEAAASKQFARCAEIQSELEQVQELRKNVKEDLNELEAAELDERIRAVETAIADAMKSRDFGKCGALQDDLDKLVSIRKKKQTPEELDAEIQRLNQEIASLMSQKQFDKCAAVQREIDELKRRREKFGPAPAPAPPSPVKPAAPAKQATPAAPATPAPKPAISAPISAPAALPGAAARPVAMPTASPTLAPQPTANAPRLSVSGPSIQAAAPKISAGGPAIQVGAPSVGPTTRPAAKTITAPSTPAIQVGVAKPAFEGRPRSGSNSSVVSTQSYARSTISMASTANRLKKKDSSGDASRTVERLRPAKALTVAEDVTVAEAAKLMKSNRAAAVIIVDGDGALAGIFTDTDTARRVVANGLDPYTTPIGSVMTPQPKCVASDDSAAYALDMMLTGRFRHLPVISADNGMVVGVLNVAKCIHDAIRRIEASSSALKQELGGSSANAMLRGMLEKMLSPSLEDILTAPGETQAPMVYENDSVLDVSLKMAEAKKPALVVTGGLRSELIGIFTPKDLLHRVIAARLDMNSTTVGEVMTPDPESAAPDTSVLDAFHIMHDGKFLNLPVVSPTSGEVYGIADVLALAVASFGQGESRDMGKFWNATFDLGHDFDDNASMSGMSISGRSTSAKSVSGASVASRARQRKNRDKEVNVRPVSSLRPSPAVVIAEEASVFEAASLMNQKRSDALLVVDTSGSLAGILTDTDICRRVLAVDLEPGSVAVSAVMTKNIKFVAPEDSAIDAMLMMQEGHFRHLPVVSRDGGTIVGVLNIGKCIYDVSKRLEHAINSTEQLKQSLEKSGSTVQQLLGPMLQKLSSPTLGSILENETRNNATPAPRVRMGTSVKDAVKLMASSKKAVLIVDGPRSDRLCGVFSPNELVMKVIAKNLDPVSTRVEQVMLGDPEIASLSTSVLDALHIMHDSQCLNIPVVVDETVDEVAGLVDVLALSYGTIETIYGEDQEKMQEFWNTALQLDQPASLPVASSSRQRTTLLASKKAAAAQQEVNRTVAQLRPSRVLTIEESATVSELSRMMGRSQSDCVLVVSDEGLLSGIITDTDLTRRVVSENKPVESTLIGDVMTRNPLFVSNEDQAIDALCRMLEGKFRHLPVVDANGSVVGILNIGKCLYDAIRKMEKSEQSNAALRQSLEKEMRGRGARGGNLSALLGGMVEKIFSPDVKSVIDHEGVEPPRVQPYTSVYEVSKLMSATKKAALVVGNRGQYFGLFTPKNMLENVLARGLPVHTTPVCEVMSEDAVTIYGSTTVIDAMHAMHDNKTLYLGVLQSESTPQAIGLVDVLSLSYGSFAKGSPSDWKAFWNASFDAALDDDDDTSSVHSFRSSFSTARKSVHDFGVPRKTSPVTGDSRPVSKLRPTKTVTISEHFTVAEAAKEMSITHTDAALVISGDGVLRGILTDTDVTRRVVALGNDPNFINVCDAMTPNPKFVDEKDSAMDAMFTMLEGRFRHLPVVDSQGMVAGMLRIQKCLYDAITRLEKAQQVSSGAIREKLEKQLLSTGLGAGLAGNESAMQQLLGPMVEKMLSPTLEGILKDDQLPPLVRASDTVMEVARQMAAARKAALIVEDTGAGPSIGHSRMNSGVAGKKLIGVFTPKDLLLRVVGAGLDAAMTCVSEVMTPEPETVSPKTSLVDALHVMDEHKFLHLPVVDEITGTIVGMVDVLSLCYGTFAKNAGGGDSSDWKSFWDMSLALARDDDDRSDAGSLRSVSVAGSKASRRLRPSRSVRGRSNTGSSVDRRESESALRPVSQLRPRPVTRINEYITVAEAARQMRKSRVEAVVITTDEGELRGILTDTDITRRVLAKEIDPDTCSVSSVMTSNPSCVQTEDPAIEAITKMLEGRFKHLPVVGMDGLIQGMLDISKCLYDAISCMERVQQSTESAATEFSRDLGTGSSLQRLLGPMMEKMVRPTVSTALEGEPKPPVVDLSTTVTAAAKMMATTKKAAIVTDGDELIGILTPKDLLRKLVAKGMDATTTTVEEVMTTDPESLGPNARILDGLRLMHDSGQLFMPVLGESGEICGMADVLCLSYGQFSNSSSGSGGGDWRQFWQTALNLQEEAGYDMDDTASVGTIEDFERSEYRGSIAAPMARDSFAMSSRFTNAAAYAELGESASVISATPTTTTSIMMRGAGDDVFVFKVSDKAQGHYHRIMCRYDTITVLFEQVRAKVNAGPDDEVRLKYEDDDGDLAVLTSDESLIEAVDMAKRAGWKRIMLLVDVVRAGDSAPKSKKAASSPAKPAARPRKLTKVEETVESEASSSSEEEEEEVKPVVEDKKKAKKRKAREAAEAAAKEQMMMIAGGAALAVGALVVGLIMVMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSY3</accession>
    <name>A0A8K1CSY3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSY3"/>
    <dbReference type="OrthoDB" id="98369at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="257" mass="29289" checksum="8DD64BB69AFA48B7" modified="2022-08-03" version="1">MKQFEKGIDRVTVTGSPVIGKSLFLAYFFTQYCTQNPTATVIVASFTTGVMDEVLVWTHEQMEHANEQKEAMLELIQRAEAKAKDEGRPFIRLYDGLPSQLPPRSRVMCCANACHAMHDKERADPRQVTLYMPVWDSDELTGGEEVLYLHMEPPPVDFEIAEERFNTFGGIARVCLSDNEEYVKQTEARLLRTIERISNRAVMVHYALNAENTDWAEVLGGTSIYVPEEGNPLKFTTESPSTYIRHLAVERMMERGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTN5</accession>
    <name>A0A8K1CTN5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTN5"/>
    <dbReference type="OrthoDB" id="79569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="49626" checksum="D840457D549C06DB" modified="2022-08-03" version="1">MKNNRTAGESNEKLGKFLLEASTDSLLSEYVERKLRQSREHSIPVTSDNEKRRGSRIPPSVMEPPPSLSSSTVSSLRSSLADSILNRTANQVVGGKEDTVVRESSSMLSTAERNYAEIEKLRLSQRLREVNNVQAWMKWRDVVISDRLLAQARKREQMEVERAVAAAQRQHQEAQLSKQDEHELEVESLHEQIRAQEQAQKEKEERDRQQKEEERRHQSEEAVARGAKRTRVWSQLVEAHLEDCLVQADKRINDVDTKLEALLELMDVDVSSARFQAASFLVNAMLEQKVENANAHVQAQQELMQGLNARSAYPDDSIVDSHINKTDGKEKHQQWQERMPTKNARFLLDMVRQRVTRLHQLHQAIARLAATVSTPNMSAATDSARLHHAAFLTDVMHERALQHLEGMLDIHYKRSLLDLPLTTTETAPLPARRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTR2</accession>
    <name>A0A8K1CTR2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTR2"/>
    <dbReference type="OrthoDB" id="153103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18923" checksum="1E1B67DDB9489EFD" modified="2022-08-03" version="1">MGPLVHVRPLQADDIPALALNEQLTDFCTRALERRDWTTKSIRVFVTEVPAFSATETSQLAGFTLVGLGYPPYFPALDESVGQMYIASIEIREAFRRRGYATAVLEFFKQEAQTLGLDVLRCECEKGWRVTLYECVGFVPVEYKGTSPEYPESHQMLELWFTKNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUG5</accession>
    <name>A0A8K1CUG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative restriction endonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUG5"/>
    <dbReference type="OrthoDB" id="124462at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="entry name" value="tt1808, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative restriction endonuclease" evidence="1">
        <location>
            <begin position="127"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="245" mass="27797" checksum="C94F4F028B37E02C" modified="2022-08-03" version="1">MDTMDIIIDVDATSDSDDESSVIALLDGTQIPAVAGRRHILPPPDPNALAPERSLFFLEYDVPDLIVRDVALPYYAAVEVRPATLQAYEWFRQHRAHDGFVGYDRCGYTFVLPPPIASVVGQKTHYRQQYRVPDVSYVEPSTWSQLSREQKNTRYLTCVPTVVVLIRTPRYSMQDLHEKMTAFLAAGTKEGVLADTKIGSLWLYHPQSTPQCVQLGPVAFESWPEFILDCQAIRDARLREERRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUS5</accession>
    <name>A0A8K1CUS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kintoun</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dynein assembly factor 2, axonemal homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIH1 family. Kintoun subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUS5"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03069">
        <property type="entry name" value="Kintoun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034727">
        <property type="entry name" value="Kintoun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041442">
        <property type="entry name" value="PIH1D1/2/3_CS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18201">
        <property type="entry name" value="PIH1_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="PIH1D1/2/3 CS-like" evidence="6">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="528"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="679" mass="75495" checksum="882B1956486CDBF4" modified="2022-08-03" version="1">MGLQTTDKTPSVASAARKGDNQHQELSEDELTTLFQEAMKRSSSSPSSAAAASKHGPKITKDEQQKFLQAMQDPEFRSLLNDYMLEISDPENRRETEAYLAQLEQEQRVPENKMLIKPLPGFVVKTKWLETQKVFVNVCSSDKLAPPSSTQVAKSAQTTGGTSWHLPYSVGPERMEADKGGARVITYDVCFHTRTLQFATTQRPFRDMVIGTCLDAVEAQLRQFHREPQGVLSRNHHVLKGVLYKSGDPVTMCLKKEVEKPATITKKGAEETITTSKDEETEAPSPPKEEPLMKEVSTVKTKTTATTPSLKTLSYQLIYRGQFEMMDHMQGHVGDAPPASRRPKELVVEIAFPQHTSAKGIDLDVNDTMVRVTAAEYAPLTITLPFAVVEAQGSAKFDKKARKLVVALPVQPPPRIDKRLVIQEDEGEDEEDEEEAVQEETKMPSVEAKKETTASVTSKPRADDAFAMLRETALMVAQDPLYQRQRQTEAAAPVVQATVPKTHETNEKELTTLESTVKAHVASDALYDDLPPLESCSEDEEDYEDPIQVEAPPSQLPSSESKQLPPRTPAFEVTETTACRSYLVQVAGIDSSRVELTILSSHSFKLRFFTAENELFELNEADIPCEVDTTRFEVDVASENMAVILYKKHKVTPTETTTAVPPPPPVMVHFQNNLLDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV05</accession>
    <name>A0A8K1CV05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV05"/>
    <dbReference type="OrthoDB" id="2996783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1020.10:FF:000001">
        <property type="entry name" value="1-Cys peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000011">
        <property type="entry name" value="Peroxiredoxin PRX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1020.10">
        <property type="entry name" value="Antioxidant, Horf6, Chain A, domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF4">
        <property type="entry name" value="PEROXIREDOXIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="12"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="230" mass="25370" checksum="746E30580722D1D9" modified="2022-08-03" version="1">MTSQTIRNVRGFTLLDTLPDLAFSSSDGTHSSIHQYFKGSWGILFSHPDDFTPICTTELGEAARLQNVGEFEARGVKLLGLSCNSVESHQAWLKDIEQFSGQTVNYPIIADESRAVAAELGMLSQDDLDKKGLPLTVRTVFILDPEVRIRLTLTYPASTGRNFVEILRVIDSLQLTDKHKVATPVNWKRGEPVVVASNLSAEDAAAQFSDVKVEELPSGKAYLRFTSQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVR9</accession>
    <name>A0A8K1CVR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVR9"/>
    <dbReference type="OrthoDB" id="108594at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="776" mass="87800" checksum="7C87776FD13C0A31" modified="2022-08-03" version="1">MLAMVTKRDWSFLAPWWPVLERRPPRVILYDDIEDHAYQHFNGTLEITPVSPQDAPEDAPEYKEVWRQQCEAMELLAMVGRVDQAAWLAIIKRITVSTYSLMDWRATLIQDPNFVVYQIRIDHDDIIRHHPTYGVEEARARAEREQTGANAQDEEEEEREEQWPSELVTQLLAPFELSERCDEYQAAYAEIVKRAPSSALEDRFENMGISVTLEIRLMLANCLTSCIDAMMAKIEEGNSLFFIELVHYTFHDAILSTEWVDQWCQSKKDDGVLVSALTFSGVDQERPFLLQMLRRHLAFSLSAFLDEPKDRHGGPGTIPELCLKMPLGGYSSPGLFGLLAAQNSLNTLRLTHLFTPIGSEVDADDQTPYLRRRRRDWQWLSYVLFSSYSAGGYMTLDLADLSLTLEDIEAINEIRHAENPFPLLHPRSAGIQRNQPVQVARVEKGVEFDPIADLVGDVNNDEDTWQEALWQDSNGCSTNLPCSFYVMDDDPTKSTVDVLVPGFGVCPVDRAKMQISLASDREVACPSSPTSTASFTRELSSLRISLRPDDPDEITGLVPFIKLFKSSLDTLSVRSGFWPMINEEMLHEIVRECSELRILTLEGAILSSLQPIIDLYEVDGCEAYNLKFTRLCVAQAGDMKELLNVMVNPNSKFSQHVTYLTLEFGEVDVDTIAALVLILMLNKTIQYVTYGLPALHLAVARDRIEPFHNEAIAGIQSFVPVASRLALLSVMHRAAASDEQSVLGRMDSMVISRIFEFASEPKRRVVCLRESRGMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVU5</accession>
    <name>A0A8K1CVU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVU5"/>
    <dbReference type="OrthoDB" id="108382at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="434" mass="48784" checksum="CDC44132EF1C29E9" modified="2022-08-03" version="1">MDEVEVELECAVYGEGSVFPVKIARDAKVSALQKAIFDDQRYHERFSFPPSALTLFLARKNDTWLKDDRHVKNFLQAGKSAEYEEMRPSWILGEDYLGANFQPGRKEIHVLVELPEAAAGEKSVTAEMDKKLDKVLEHIMQPKRKRYVHSEMSSTKGNALLQDLNIRLKFAGTVPFTARYPAPVEGFKWESIDDGRGQNIAFTEEQQRERYRTYVEDNIGDVLAEKKLCVLGVEKGKNILTATVPGHDIDLVGRTDILVLSALAKQFPHYVKGLPEVKMLIEVKRNVKGGSMFQALSELIALDILVADPVMALLTNLTDRWQFFWVSEKNNNYVNIQTTTITEPGAAFAVIRTLLAQSPNGDADITLPYFEGPVKRRKLAQLLPSIGEGGESSGIREAIERYYDIASVLGPDIDMARSVAHQIVRTIPTFSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVU9</accession>
    <name>A0A8K1CVU9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVU9"/>
    <dbReference type="OrthoDB" id="1925570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36074">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36074:SF1">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="272" mass="30570" checksum="3C7E2C2011CFCAB0" modified="2022-08-03" version="1">MSVVAHKNYLADKKPFFKHFHPRDITITAVRSAVMQGAMVANFYMASLALEEMSDEEDPDSEDDEIDRLKKKAKKELKDQEPYEPPSPQEFTLLCLTSFVKSISVTTYLRSLEEAAIHFCRPQVVGKLVKDSSKSATRKYLRHHSRWSAATMMVKTGMRANMLSHLAIFLVEETQQIILILYRKFVSKETKNSKKSQKKLRGADDKKVLDEEEDTEEEHKHPTFLEITTKNAYRSSIAVVTGGIGAAVGTLIRPGLGTVIGATLGDTVGYLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCG4</accession>
    <name>A0A8K1FCG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCG4"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="61645" checksum="7F8ACC7559CE2690" modified="2022-08-03" version="1">MARQAIDVQERESLASLASKNETPVDDDVSGYVLTQSPREPKDLEAGQGPNIYSKKHIGLLVQYFSAGLVYSCVYRLIYPFLNNYLRMSGVTTSSVSVLTAFPYTCKFFFGIVSDCFPIFGFRRRPYIAIGMAVCTICCLVMAVLPTGDPYYPDPSLAYVNPAKLTQEQKDSINYDAPNSGTAFVCLLILANMGIVVAGAAIGGVLVEFSQQEPEAVRGKAQTMIWAARYLGSVGASALVGFGLNSRDFGGTFGGSIGVNSVMGICAVVSLGAAISSWYNNTETKVVERLSFRGELRKMYELMHSRVVYQIVLFQFFQNMFSSVSVTASYPIQSVWAKVEPLNSSIAAIISSFIGIGTLSVVAKYGLGWNWRWIIVGCELGVIALDLFPTFFTVWDVFRNQWFWIGIPLLEKVPSSISFVISTYCMVEIAEKGNEAAFYGLLVSVSGLASPFSTVITKNVDANFDIGLKYLQVDDTHVRTQVTYAYLFQYACKIFSFVFLFLLPRQKAETRELKSKGEKSVVIGNLTIVMLVFVFIWSLMTNVMSIFPSTACLKVAGGTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCW8</accession>
    <name>A0A8K1FCW8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_014885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in splicing regulation. Facilitates post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000166">
        <property type="protein sequence ID" value="TMW54932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCW8"/>
    <dbReference type="OrthoDB" id="340500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22526">
        <property type="entry name" value="KH-I_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01724">
        <property type="entry name" value="Sm_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000038">
        <property type="entry name" value="exosome complex component RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000073">
        <property type="entry name" value="Putative Exosome complex component RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000008">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049469">
        <property type="entry name" value="RRP40_KH-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041054">
        <property type="entry name" value="Rrp40_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034102">
        <property type="entry name" value="Sm_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18311">
        <property type="entry name" value="Rrp40_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21262">
        <property type="entry name" value="RRP40_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="8">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW54932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="359" mass="39483" checksum="528AA7E2A6E084A7" modified="2022-08-03" version="1">MKLVRFLMKLSNETVTIELKNGTIVHGTITGVDISMNTHLKSVKMTVKGKNPVNLDSLSIRGNNIRYYILPDSLNLDTLLIDDTPREKRAKWLESAKADEPIDATADDEASRFLEDAQRQVDFLFSPTVVLPGDDVTEILTKTSKNVRLGAGLRLLPGDRIVCTNAGVLRYRPPNRYWVEFDHKRYNVAVDDGVIGVVTDRNASSIVSSVTLGCLAFDGATKRNRPSLRVGSLVYARVLKTNPDMEPELTCEASANMTKKDWMTGLSVYGELTGGYVFKTSISLAKKLLQDDSYVLQALAKSIAFEIAVGLNGIVWVNSRATKHTTVVTNAILNSETMSPSEIDVMVQQLIATTSRDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCY7</accession>
    <name>A0A8K1FCY7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCY7"/>
    <dbReference type="OrthoDB" id="10470582at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="135" mass="15725" checksum="95A3620EA6A62DB9" modified="2022-08-03" version="1">MSPTPAVQLETAPPMPSSSHEHLQCRATAVDAEQERTWNEELVQAETLLAHDCWEWVRTSVQVVEDELMQLELKHFFLRLYRAMTAQETTAVLDEMEAWRDYVHIAFPLQREERESIQAMFMLGVDKQMSLQHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE37</accession>
    <name>A0A8K1FE37_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE37"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="116"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="172" mass="19345" checksum="260C967512595CDE" modified="2022-08-03" version="1">MVRARRSVQKVVEVCATSAKVVALDSDGTNEWRRVNLPDLIVEALKDDAVRLCIDSNGNHVIQRALQFMKPEYNQFVFDAVCKECTTVGTHRHGCCVLQRCLDAANDTQKREVITQVEKQAMKLMQDPYGNYVVQYVLDSCTAEEAYGVIVKPLGNVFELSIQKFSSNVIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE43</accession>
    <name>A0A8K1FE43_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE43"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="947" mass="103017" checksum="5EB41B53E5FE3285" modified="2022-08-03" version="1">MKEATPAAMTDVAVMDGESSASTERTTSAAPLAVVADAVDAVDARVDGVAESTSPKMPIHHILNDASDEIVGESEPMEQASTALTVMDVAGVHTSAPPSTVVSTTVKNTQVSTVVPVVTGQDPATAQLLLSLASPSLHRAEPQAQPQVVAEEPTQDDVEMEIAPESQSSTQPQEPDEEGKATEPTSSTIPPVSQEAKRTATAKAPVSEFMETATASTEDVAMESTDADASSGRSRRPRRASARAKAAGLNLVRPGEEPIAGAPSGSTARAREKRPPPRFTVESTPPKRSRKAASAPVPSSAESVTHTEDEDVEFVIASENVQKPVVETKKSKSRKRPGISQRQMAELIERQTDPIPDMPANSHRVDQGRTIRNCMFCKAAHSTHTLFHCAECARVYHDRCLANKYRPMVDKDQPFEDQLEKLTLHHDESRTSLLRCGSCLAGFMDIFRGDAFQWDCDCPTCTTAPEKIVAYRRHMIKLIIEQHNEQLDAKKKKGKAPVKAKTGGAGTTKSNPKTTGATPARKGSKRTRGAAAMDDSDVLSTRTRGSSRGVSDENGEETGSVSGDDEHGVVDADSKENNLDDQANAGGMDVDNEQSDVKGTEKMPASQPSTTPIGVTDEHEDSKLSSNGHNLNSRAVDSGEYEEPLTLNTILEHVDIQAVDDECVRIPIACSATASMQQGGKFKLGTLVWNKRKSSKVSCSCCSNTGKTQKWFVEHTDPSLVKGEKVEFLHYLFAVRRDLGRLYPLQDVVSLVRGQFDALPRSQGTARTKKLRTASDADDEETKKEQERNRHLDRLRRVRWGKGQKTSPSTRGGVQPKYTVELVCSDPRYMHKLDNGDVRDKASDSDIGTESGYKTGTLEVCVFPFKRGSVTCKCCDASMQLVDWVNHTTTSGKIDDKMAKHYLYVRLHESNLTVITFLKFCMSLDFVSGIDDQVTLNKTLDRIVKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFF9</accession>
    <name>A0A8K1FFF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007094</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFF9"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000929">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="338"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="743" mass="82281" checksum="EF8606D273F54F2F" modified="2022-08-03" version="1">MDWDAGRVSSMGMESAQVVAARDAQDTSPIAIQRRLLEFLRNFRVGPLFFYREQLIANYRRNNYFFTMNLTHLSTYDQLLQDLMLKNPKEYLPLLENAAKEMLAYLLVINRTETQSFDGTASTENENVQIKNLPDIQVILTSDQATVPLRHVHAQEINKLVKVPGIIISATRVRTKCVSAILLCKNCGNTKRVAVSGMGGINIPRVCDRNREEDPAGEMCPPDSYIVVPDRSEYVDQQTLKLQENPEVVPTGEMPRNLALIADRNLVDRASPGTRVSIVGITSVVNAGTKQVGAVAIRQLYLRVVGIEIDEEGAGRAKATFSPAEEEKFHEMARDPMLYDKLASSIAPSIYGDYTTNIKKAIACLLVGGSRKRLPDGMILRGDINVLLLGDPSTAKSQFLKFTEKVAPVGVYTSGKGSSAAGLTASVIKDAKGEFYLEGGAMVLADGGVVCIDEFDKMRESDRVAIHEAMEQQTISIAKAGITTILNSRASVLAAANPVFGRYDDMRSASENIDLMSTILSRFDMIFIVRDIQDDARDRRMAAHVVRIHTNAQQSTNANKPDVDEKTGEYEPWLLKKFITYCRTRCAPRLSVSAAQALQDFYVGVRDDVRRNQGGETTIPVTVRQLEALVRISESLAKMKLQNEATVDHVREAVRLFSVSTMNAAKDGGTQGLFGGFHEKAQEVEQSINRTLRIGARVETSSLYSRLEAQGYNPNAIQRAIRAMVQKGSLRQLNQYKFVARVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG40</accession>
    <name>A0A8K1FG40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC-2 type transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013694</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG40"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter family G" evidence="8">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="140"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="37905" checksum="1F3C12AA6A846B68" modified="2022-08-03" version="1">MAETVVLQLQQLAHDGRTVIATIHQPSSEIFALFDKLYLLTDGSTAFHGKASDSVENFASLGHQCPSFMNPSDYFMRQLVVMDKATDQAGVERTERLKLQWKKREHVVSAGGNSRSQSPSAISNEEAAAYETSRLGVFDQMLVLTRRNFVRIVRDPIAFQANAFTSLFVALIVGLICLQLDLNQKGIQNFAGAFFFIVVNQTFSAANSAFLTMPLEIPIVEREYNAGLYRLFAWYFVKNMSELPTQVLMPVIFFVPTYFLVGIGGGFDVFIAMQAIIILINSCSVGLGYVVSGISRRVEIAPIIGVMIILPFMLFGGLLINSEDTPDYFVWIQYISPIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGD0</accession>
    <name>A0A8K1FGD0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dolichol kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGD0"/>
    <dbReference type="OrthoDB" id="10053152at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="45858" checksum="12518BCDD6798616" modified="2022-08-03" version="1">MPTDVTDMTAPPPMEVAHGGANASLTEPPALWSDNLSSFDYTFMLGLPSGALVLAFFVLRVLWRPKAGPKFRLPKQVPTYGTIDDDAEHHGYEYDGDSNDLIYAGQVAGRYDTRWTRTFDFTFLVGMFLFATTLVGLTCVYKPELWSNGTFWMSLLPKLVVMMGVSTLGGIICRLFCIVDDAGYVITERNSKFKVNYTRKFQLLAAYMIPLVIKPEDACKCNGALELAWGDFVTLLAFLALIKPIRERSTFFMLQFNSLDRPEDRPHTLKWLVAGNIFPSLFVLLFFRYLFERTTQSELVFILVFVTSIGDGLAEPIGIAFGKHKYSTTSCLSKRKYTRSYEGSAVVFLSGMIFPAAQYFDFDSPQQLMLTMLVLPFVAAYAEATAPHTMDAPVLMAATGCVLYSVIHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGK0</accession>
    <name>A0A8K1FGK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein axonemal light chain 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000131</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dynein light chain LC1-type family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGK0"/>
    <dbReference type="OrthoDB" id="266138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000049">
        <property type="entry name" value="Dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF73">
        <property type="entry name" value="DYNEIN AXONEMAL LIGHT CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="188" mass="20956" checksum="42E1EB9BF233F134" modified="2022-08-03" version="1">MTTCAQAIKAWEAKNGSSGEEASVIKLYCQIPPINKLDNSLNTLKNCEQLSLSTNSIDRLIPLSGMKKLRILSLGRNQIKKIEKLDDIADTLEELWISYNLIATLDGLSGLTNLTTLYLSNNLIKSWDELDKLASLPKLRDVLFVGNPIYDNISKEEARIQVLKRIPKVAKIDGDMVKQTERDAALGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGN3</accession>
    <name>A0A8K1FGN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tricarboxylate transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_005573</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGN3"/>
    <dbReference type="OrthoDB" id="44467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071913">
        <property type="term" value="F:citrate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000140">
        <property type="entry name" value="Mitochondriale tricarboxylate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="99"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="203"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32481" checksum="E26FFE0F46D9E87F" modified="2022-08-03" version="1">MTTKSKNPIVATTAGAVAGGIETIVIWPMEMIKTNMQLGTMRQHYIGMVGGFQYHIRSDGVFSLYRGLAPVLIGSIPKAGIRFGAFDFFKHRFAGQHGETPLRNLAAGMAAGAIEATLATTPIETLKTKLIGANAGMWEGTKMILAKEGIRGIYQGLFATILKQSSNQGLRFMWFTEYKRRITPETLERYHLVKDANKLTGAENAAYSLVGGVTAGIFSVFGNNPFDVVKTRMQGLNASKYENTFDCVRQMLRKEGVMAFYSGIVPRLGRVIPGQGVIFMTYDAVSRVVTKYVENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH13</accession>
    <name>A0A8K1FH13_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TLDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH13"/>
    <dbReference type="OrthoDB" id="289228at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF108">
        <property type="entry name" value="RE10231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="1">
        <location>
            <begin position="214"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="454" mass="51122" checksum="5584A309ABF557CA" modified="2022-08-03" version="1">MGTTQSRGESEWKGPFSDEEYDRLVVVYQEITSGKSNAATQQALQERLTLPLHDDLPSEWREGLGRLGASFFELCLHSRELAGSSDTSTQLKLNDFVQGVAQCIRASSQAIYRSLFHLFVVDKKSAYLNEDEVHQLLLACLLMTNAQIADEEPRELVRMIKKLAESALPTTTGDSTRQLSMDEFLRWSSAQLPLMFSAFTTWISKCFLDSLARAAYNPPVLTHKSDILSKTQFGALSLIYTPLQKRMDRLYTNAKDGLSFNRLCYHILGYGGPTLIVIRDTDGDVFGMYCDTEWRETTKFYGGNGCFLFRVEPYINVYRVSASDANENYMYLNTKGFALPKGIGMGGTLNGFRLFLNEDFDDNCYSAAKCLSFEPGRLTKKDQFAMDAIEVWGCGGDESLQRQGQVRKDTAEMLDKMRKVDKAAFVGNDFDRSMFLGKTFGHGTDQARIADDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHC0</accession>
    <name>A0A8K1FHC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHC0"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31733" checksum="91D02428AC1C8B3F" modified="2022-08-03" version="1">MADHREEATLSHQEAGLVNVVNDKPEADYVGLTDGVSKKPRFAVSNPHLRECLAEFLGTFVMMVFGVGVNNQVTVSEQANGIYLSISMGWGIGVLLGIHASGGVSGAHLNPAVSTSFALFGKFPWRKVPGYIISQLLGSFVACCFVYILYYQRYDAMDPDRMTTQGTYATYPNADISIGVAFYTEVFATAMLIIGLFSIGDAQNQPAHPSAGPLHVMLLIWAIGMALGTNTGYALNPARDFPPRLFTAIAGWGSKVFTTRNYFWVPIVGPVVGGAIGGFVYKLFIENHHPKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHZ4</accession>
    <name>A0A8K1FHZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="11">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_002197</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHZ4"/>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000140">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="13">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="12">
        <location>
            <begin position="205"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW63256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="41743" checksum="76051C1D68BCCC10" modified="2022-08-03" version="1">MSAPQPITCKAAICWNAKEDFVVEDVIVAPPKDGEVRIKILATGVCHTDEYTRSGADPEGIFPCIMGHEGAGVVESVGPNVTTLKVGDHVVPCYTPQCRNCKFCKSTKTNLCSIIRSTQGRGVMPDGTSRFTCKRNGETLFHFMGTSTFSEYTVLPEISVAKIDDSAPLDKVCLLGCGITTGYGAAVNTMKVEKDSTVAVFGMGAVGLAVIMGAKAAGARRIIAVDINPKKFPVAEEFGATECVNPLDHPDKPIQQVLIDMTEEEGFGGLDYTFECIGLASTMRAAIEACHKGWGQSCIIGVAASGVEISTRPFQLVTGRRWAGSAFGGFKSRDGVPELVEKYLKKELKVDEFITHKFDLAQINDAFHAMHKGDCIRAIVYFNGVPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIM2</accession>
    <name>A0A8K1FIM2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009312</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIM2"/>
    <dbReference type="OrthoDB" id="164313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="568" mass="62477" checksum="805F3456F405A0CA" modified="2022-08-03" version="1">MMLLSKSQYPHMSPKTAAHCDTNQSAMHYMTAPRLSATTPSERPCSIDMVRTDMETQNDRFVAGNEFFNYEQYGSLRPGLMPVELFSMEYIGLAVQCLLSGFVFNYCAYGYGAILAEYLRGYNSGYATAARCVLFWPQCFAIVIGLYSDCRPLWGHRRKSYMVIGWLVSFVFFGAIALVHFFTASSATSPEVQSSSYVTVFLVLSLVASAGIQVSLVAAIAFSVELAQREYLRARGRLQGTLIGLTCVGGLVAEVLISQNVSYHGMNMTSSISVSGAAGLIAATCAVAIPFCMFLMKEIPVSSSAGHATSIKKRTRELWQFCSQNLVYRVMFFIAGYTFLMKLNNLSARAVIITWSGAPWTATTSTIVARGVAKVLGVIWWVLLLKNTNWKLLAVLGTGIFVICNLALSIFTIFDVVRSEWFYNIFITIADVPLAWLLLYVYILPTEISNIGREGVVVGMCLSFQAMSELASFTVSTLIPHQIGFQVSPSDIKGDSSSTRMRVFAAIMIGTTFNLLALAMVPLLPNQKLDAQQLRAFGGYNRSARAVLSVVFVALVLFVIIANLIFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ25</accession>
    <name>A0A8K1FJ25_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012543</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ25"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:L-serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019265">
        <property type="term" value="P:glycine biosynthetic process, by transamination of glyoxylate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000049">
        <property type="entry name" value="Alanine-glyoxylate aminotransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000027">
        <property type="entry name" value="Serine--pyruvate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="24"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW61352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="439" mass="47652" checksum="71A2C6BE8478F10C" modified="2022-08-03" version="1">MTKQVLCMNPGPIEFEPRVLKQFAHEGISHVDKAVIEIFGQCLEKMRKVFLAPDGQPLVVTGSGTLGWDMVGANLVNRGDHVLVINTGYFGNHFGECLEHYGANISHLRAEIGSQPTLLEVETELKSGTNFKIVTITHVDTSTGVLADVKAIAATIRKHQPNALIVVDGVCALGGEECRMKEWDLDVVLTGSQKCVGVPAGLSLMVVRPRALQAFEKSTSTVKYYVNWKHWLPVMKAYEARQPSYFATPAVNHLFALNEGLTILLENGGIEQRFREHKLVANGIKDAIKALGLSFVTDATSGAHTLTCVRYPAGVGAADFLPKVYKRGVSLAGGLHKKIKTEYFRIGHMGPSTRRLDHALKTIEAIEEALIECGYAVPAKGKAVQVLKALKKDIPLKPTCKYSTVVYHGCPVPARCQVYTIASLAAAVAAGFLLASLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ30</accession>
    <name>A0A8K1FJ30_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ30"/>
    <dbReference type="OrthoDB" id="118485at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035487292" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="4">
        <location>
            <begin position="90"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="312"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="526" mass="57738" checksum="CE2FE994A0C563D9" modified="2022-08-03" version="1">MVRVIAAAASAILAFAGRAAAEAACTVSDTEFVGFTHYLVGQHRLPGSIYADCHDGTPTCYVDDGISDTADAEVDCGSVNVESRRRELGVFVSSDRAWPNRVVCYKWGAQFSDKAKGFWNTAFKTYQEKVDITWIESSKCRSTYGENTKVCNNCQTAINIQTSKAGCYAHLGYIPNKDYKPELNVGNGCEWLRIYTHEMGHSVGLIHEHSHPKREVIVLRNKLRVGSSNYVKDMNAPTSTYDRMSIMHYDGDEMCIPKDPKIKFCDVSETEANGCVVPKDEHCDRSKQDTFGRGETLTARDIEAINKLYEKEKRHEKSPGGGAPAPAPAPAPQPAPAPAPKPAPAPAPKPAPAPAPKPQPARKSIQQEMLDAVNAERAKKNLKPYCLNKKLQTAAQKHSEDQAKHKKLTHDGSDGVNFADRAKREGYNWQGLAENVAAGQQSVADVMKSWMDSPGHRANILGAHTHFGMGHAKGGNTPYWTQEFGSGRDEKCDGESRSLDFEDLVGEPVNATATEERYGYDFSDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ51</accession>
    <name>A0A8K1FJ51_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycoside hydrolase family 5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011426</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ51"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923:SF2">
        <property type="entry name" value="ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35923">
        <property type="entry name" value="MAJOR EXTRACELLULAR ENDOGLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="179"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="634" mass="68755" checksum="650C63C6BE4E04AA" modified="2022-08-03" version="1">MYQESPHGTESNASTTPGRIWRDTSEEQTYGNYLDNAQGNTPHDMQLRPTFAGARMTGAGPGAHPDIAVGLLEDDGSDGGAAAVAAKKSYSGRKRVWPGALFLLVVCLAGTFAVTYFGVQQYNAAQKQQAISEEFTSLQKPKKALPLKVCRVPNYVTDKGKLYAIGGSKDEKHEVHFTGINWSGMENKEGVPHGLAAQQTNLDAIAQGLNDMEINAVRLPLNAKMVLDDSAPDVNSFVSRTSADLFAVTTYVDMIKKIVQGLARKQVAVLLDLHKIDPEYAESTSEELWYTDEYPEATIIEMFEKLAKELCNEKHYNIIGVDIKNEPAKGCWPAKDSDSYCPKNRNWPRAVERIGDAILKVCPNWLIVVEGLAASNIVKKINGKEVTYSDWLGASLQNATANPIKLSIENKIVFAPHFYSPSVYPSSYFFAEQKALPSGEVSVTEYPMTAEGNKSLETAVTTVLDEAFGEILDKGTAPVFYGEFGGIYGSKELLADKTSTRVIDIVIKYAEKKGMIGGFSWALNPDGNYDFNDVYVGYSDKLEPWKFGLYEDEKWDGYNEDYAAGLRQLKGNGIIPCFDRIVSGSSAAGDASTDGSSDVAASAIVGSTDGTTADTAGTVATTTTNTTTATTTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKA5</accession>
    <name>A0A8K1FKA5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKA5"/>
    <dbReference type="OrthoDB" id="74580at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="93" mass="10403" checksum="BBEC8E88D5B6BA29" modified="2022-08-03" version="1">MGRFLEGALKPGSREFVILLNLVLGLLFLVMLTVVYTELENSMHVFVLLFIIVGLTLSINWFIVEANRLKEMQVAESTTGASNTKQTTRAKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKQ7</accession>
    <name>A0A8K1FKQ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKQ7"/>
    <dbReference type="OrthoDB" id="69725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1264" mass="140881" checksum="928B989BACEF3752" modified="2022-08-03" version="1">MASRKCTCLVDTESDSEEETPLQQVAVAVSDVLAGDQSDARGVISVDDSQMPLSRRISGYRDSLSTSTALHNSEALRQAHVLQNVFCACYDIETVVSLIQRRERVFSPVQVTLLRKENMATVFRYATSLPDQHGSSRSAALAEDADVSTAHMNPEQYRRCVVATEIILKFYLKVIAWHGNPKTVVEPTPRQEQGHSNSLSAVGSPPNEITEEERQLAFQRRRYSADMSTLSPTHRTLAYGSTQRGRGAQRSKQNGLYSTVSYGDMSNAFHNSEYDVIDSIEVRGYILRLEDLTEEEWGSVFAQLFHSLSKKDGFKVSMTTISEVSGAANDIEKPLDSVLVTNLAKIIKNFVVYPSVHRILSSMTWPGKRGSSGKEPLLPALVSYAYSPDIASLLHGLVHLAQRRHFSSEAIISSFVENISSSVNGHSRLSPSSVFSVKRPRLHDRITACADVLVKILTQEFPNTFRYYIQAKIQLASFERIEAFERELFPPKIPPSDPSLHADIMSNVMTSLLDDPDTVIRFAELSLAEIRFLDAHHEYDTGIPRILLIDVLRRAIECSLQDRVQLDLFLPGIMRVLDTLCASINFHQHLSTISAFASRGCFSDSDSDDASHEDEEDEEEEDDDEQNNNSGSTRSSRSVNPDTRHLHNGTATSKGPAKELPTQLSLSSPAAPQVIEQRPLTSILLIIHIVDFLEAVIRMGIDSVDSRLMRLDLSTSLIQLFDHFPKANILHCRVLKLFLTLVDRKTTGRVNNPFLRSVFRPPNSIQEFIMTKLHRSSKTHPYDAHLAILGVKIDKICSAPTLQQELIRQYCSATTGWPEFCSSLVASHYQQMDALDDLALSISASASVHSRRGGEMDDVYPLARTSSSSCDYLSGELQPFRRLPMEKEGIGSSQNLALGTEAVNPTDMLRSRTQSQYPQSIIDILRNDTSTSFDIVEDDETITGYAYQKLAKWVKVKLKFDKATCILVCEDVSHRSSSHQSSTAGNVSSPTAPSKKASSSTSKLKQLLKQHRLLPWTSRPKKLVVCTARQWIAFGRTVKNPHVGAFGFQIDVFDRIREEDQTLTFVTRSEKTRTQWFESLQNAVIAARSQRQSFTEVDEEANIMLVKCVAMQREGGQMVFMAVPDVHVLNPVISSNFSLKSEVPEEIPFWGTFHGSHGVSKYCSLFNQCLSVLSVQEKQVYASGFSVIVEFEATLQAIELPTAHDTPGRHHLKLQLPIGSDADKTVTCSFTDTYLISGNQIVSMTRTIADSEKLVRILCEDVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKS8</accession>
    <name>A0A8K1FKS8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIPK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKS8"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00139">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="283"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="647" mass="73548" checksum="7A1723E566E418DC" modified="2022-08-03" version="1">MTELASSDPFGRALAASGGVGSFELEFEGVETVNTLASVASILGCVFIIVTYVLFQPIRKYHPATIIWIALLGLLYHVAVLAETQSFGPCKTAVVTQIGLVGQDMYFIVLAFRFFYSTKYPFRSTKLLMPLSHLFVLLLLVGLTYWSSNLGANTMYPYGICWFGTIGDHNKLALFLILMVPLAVGYVVSIGLYFAATKRVRVGSRNQLTNLDIMRRYLLCMFGYWCAIALIYILRQPQVTPLDSTFEKSIRFVGRMLFTLKGFISAVTWSSLLHTRTAFKLWRKGNWDEYIEIYDATWVQRQQTVYYATKGIQYSTQLATEEPFESAPTRSFARQFFKARQTDQKAVFRDFHPSLFQEIRQLSGISNEDYAKSFRGRAKERFSEGKSGSFLYYTGDQQFILKTCSPGEQRYLLRILPQYIAHLRKYPNSYICRYIGCHELVVDGRSVTFIVLTNMLTNPNMNIDEFYDLKGSWVGRYRAPPRDGSQRVCTYCGRDYIVGMSDEVCERNPIYGQGHTELSTGKDMDWGDRRLRLPPGLSQQLGKQLYEDSEFLRRINSMDYSLIIGMARSPSSTINLDDDGVIQAMHLKPPGQYGLKDERPVMEPDDIDTDEVVHLDDTTYVLASSPTASRSRELVPNACVTALVSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL29</accession>
    <name>A0A8K1FL29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL29"/>
    <dbReference type="OrthoDB" id="10606675at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035474526" evidence="3">
        <location>
            <begin position="20"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="381" mass="40637" checksum="F2D5C31DC266EB48" modified="2022-08-03" version="1">MVFKRSVALLALAATVAAAANVEVETALKHPVVKEVKRENGQVRIVLQEGAVVKKHKKHHHHAEVKKPEVKKPVVKKPEVKKQEVKKPAVKHHHHAEVKKVEAPKKVVHKVQEEKKDGEIIRKYAHGTVRIAAKNQPEQPKEQSKKKVVHKHAKQITEEPAGSTEGDIVDEKDVELLEGETLALNFEGHDLNVTVLNNGSIAVVANGKTTILPPSDDITLDFDGDFDLEEESSSASGSGSVSGDVGTVPQPSSLLETVEGDISSVAKKFTELASKMTGDSKLFSKDAAPVVFVCGVLGALAAVVGIAAIAVGRARDNAAAADPASVLAEATEDVDVEANATSEDNSEEEEDAAADDSESLDDSESENEDEEGKFTNEVATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLL7</accession>
    <name>A0A8K1FLL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLL7"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF22">
        <property type="entry name" value="SLL0786 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="150" mass="17006" checksum="4545C60941109FAB" modified="2022-08-03" version="1">MPLDVTQVSFTEGFETCKALRYQVMIVENGFDPDLDVDADDFKATTRHFLGRDVDTNEFVAVARCCVDATRREGKIGRVAVLAKCQGRGYGAALMQAVEENVKNDCDRLLLGAVMYKVGFYRRLGYERVDETTFFDETEQCWMAKSISHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLS3</accession>
    <name>A0A8K1FLS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLS3"/>
    <dbReference type="OrthoDB" id="5977668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF17">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="232"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="473" mass="53784" checksum="85EA3354787D7AD1" modified="2022-08-03" version="1">MKVVVVGSGIGGTSAAYHLVKDGHEVVLLEKNDRLGGHTYDMEIDNEMVDIGFMMFGDSNPNIKDWFKSFGITEADGTTKKRIPMSLTVTSEIEGDVQFSSRRPFKGIGGLFDRRIWRILVDIYHFTWELMNMPVKSGLTTREWSKLGQYSPEFFRHYFLAFCAILWTIPKHDVLDLPATQFLRCLKTHSNSLYIPLWQVILGALGRRTDRPRHQWWYIGSAYIEPFLKFFTEHNGTVRYNAEVKTVEKGGKAVILSTGERIECDHVVLATHADESASMIPWSEEGVKSLMKYHYHKSMMYVHRDPSFLPPDSKVWSSWNVLITKTDEYILTYWMNRIQRLKSKKDVFVTITSHDFAGKKPAKELTISSFRWDHPRLLADCIPQDEILKEEGITLSGAWLGRGFHEDGFVSGRRAAAIVRDPKHAKTPLYEDPGNIAVPAVPPFSVPLSIKLTTAAVVGAIGYGVAKLIERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLW2</accession>
    <name>A0A8K1FLW2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLW2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="373" mass="41709" checksum="AC31E0B1C643E3F5" modified="2022-08-03" version="1">MKRMNEVLAFMFSPRALENYSAAYRETRDRLLGSVVSPNRHQELEKMRVPIIVDGSCWNNELLEAFLAQTNAIYRRQREEQLSGSEISQLELDAIRTDMDRVHEGDLAIAVGDHFAQRVVPLVKLRIDGFKEPKTLVCRALSGQSRDLELSMSGSMALESDRAAVFSSIAAQSALKKACPLLKYLELRHVDGDGIDCIVDAFETGACKLSALNLNGVVITDGVESLFRIFKALMNPKTAIAQQLKELHVRTSASGAWLARQLLGVLDRNHALQTVFVSAAKKRLDQANGSLQDLEPVYFAQPHRPFPLRSKLSLLSVADEASSGVNPIVQDALSRLNRTVFQQIFEYAAPPMERVVRAVDDRNPLRRRRNEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM77</accession>
    <name>A0A8K1FM77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM77"/>
    <dbReference type="OrthoDB" id="2113965at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029329">
        <property type="entry name" value="DUF4472"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14739">
        <property type="entry name" value="DUF4472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="462"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="656"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="903"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="967" mass="109131" checksum="DDF876393B9A97C7" modified="2022-08-03" version="1">METEEDGAARHGVAIQTHAVLCASSRGGTTSDASVVRVKDGKTVELVNGTDTVGVRVDHVFEQPTAQDVTERSLQHLVKACVEGVNGSVLAFGSIKSSKSECLFSRMGNRSLVDVLMESLLSGLENKVTALKNGGARTPKAPFSYTVRFSFAEIYEEVMTDLLSPSKDPKNQCVENGGLSLSAPIAEVDTFSRQVVAGARSRRKNAGLFGSATNYSSAILRIHIHQVFQFQDATPQELKSTLDIVDLPPVDRLAQSNSTSRLSEGPLLNKSLFALADCINLMVETPTSSSGYPPFNSSRLTQLLQEALGGNCLTFAFLFLVEGDYIGSKASLSVATKLPRVKNYPVVNNDVIRGLLLRNRHELLHTKSYLAGAVLSSSSGNSDYIAKILDLEAKLNHETLEKKLLKEDKDKTVSVMHELKEKYQNLFDNEIAIRKELLVCEQEKLSLSKAFVDFQMEKNAQIQDLDSEKFELETKLIQAEEMLVQIQDDDTKKATQIQDLCLKVSEVVQEKQSLGEELSLLQKKCRQLEQTLSQEAKKNQQLSLELIVLVNQKQKYQKELDDIDKKNREIKKQGDDIAGREHTIQIEVTDLKGRITNLESEIDSLRKELARRDIEIERLELSKRSAEVDFSKQSEQILSGRQAQHEDSRLKFVAQVTALSQEKKVIQVQLDRLEVDLQKTTKEKQDHVAAWMAKSQEYEELLVQNERLAHENQSQVDEFRLKLSFISKGAVDHAVDEIVQSYQRREKDLRSQLHVYQQMVNRMRRKIPSPMTHGLDGVVPTNQSDAEDNEEVKHLQERLVRSEETVSAQMEMNAKLSLAVSALEESLEKLKTENQELQLNLSSVKDHPQPHDHEYLQTTRQMQDLLLQQLDEIRKIAVQGSTNRIPSYSTNSALKDEHESADMSKLKQEKAVLEQRLATSKSEWTKIVEQVEQRCADLLTQNVILTEENQQLRQSFKKLLARLHQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMJ9</accession>
    <name>A0A8K1FMJ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LAMTOR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMJ9"/>
    <dbReference type="OrthoDB" id="343907at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015019">
        <property type="entry name" value="LAMTOR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378:SF1">
        <property type="entry name" value="RAGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378">
        <property type="entry name" value="REGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08923">
        <property type="entry name" value="MAPKK1_Int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01278">
        <property type="entry name" value="MAPKK1_Int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="142" mass="15602" checksum="F70ED193548AB3A1" modified="2022-08-03" version="1">MTKEEMSMEDADLNPVLTEQLQSVLDRFDKLYGILVSTVEGVPLLKVTREQNGLSSYEYAETVLPTVFAGAAEQIGKLKFGQVKSITSFFGDLVLLHVNDMPLVLTLVTGDSSQLGVLQVVAMQLRDALYPLKRSVESADVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNQ4</accession>
    <name>A0A8K1FNQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNQ4"/>
    <dbReference type="OrthoDB" id="101030at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="684" mass="76838" checksum="271EBDD81AC44E2F" modified="2022-08-03" version="1">MEMTDKRWECMASWWAVFCGHEGEMATLASSHHVYSEYAWIELTLYVTNDANHRAITREEYEDVLEAMELVSLLACVDEDAWIQGLLKYTSGSSLVLADRGSYQPPRFAIRLVGYRPEDVEEDPDAAPACIQDAATLIHDMIHHMFSPVRHSAGFQEVKNELLSNVTDPSVREKCDQIKIPVVLEGMFWDNAVYTTFQLDLEDVYSRRHANLSPECPIWLEAMSISTEDPQASVEEAAQLGLLLSQRKLPLRDIDIFDIKWTSSIVVNGLKNSMHVNEVSRRFDLSGMYYSASERVAVFSALAANTSIKTMRLWLLQDWSESEHETTRRATLQWVAFSIFSQYSQSAIDTFEFEDDSFTTQNAQAMREVLTAANPLQILLDSSESECKTANLLEDHIISTSVVVPTGTKVWIIHNRPSEPRVDILLPGCGVYPVERSKLTQPEVVYRAKAVTFLKLFLDQGDNDFAPFIQVIGSHIERLSVQVRASTGSISSSHIQQVAGSCPKLKYLVLDGMDSEGLQAIVKAFDSALPCLDALHLEGFMTKEPEDLMQFISALGDTRHRMSLQLRELHLDLYGFDLSIDASLALRSALMSNNVLHTVFLKPGRHNYFEINDHVQSLPDVLIPIPHKPLALRSKFAFLSIVHNLSASDVIQDALGRVDSAIISLIFAFSAVPTKRIVVARRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNU5</accession>
    <name>A0A8K1FNU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNU5"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="16"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="45780" checksum="F8DDB962DDF44A5D" modified="2022-08-03" version="1">MMPDVALDRKLFTMLEMEGTRYASFFASLEKTGPQLVARDTALGFFRKSTLSEAQIETLYALLKTAHIELNVQMVHETEFIMGMHLIVCMTKRGLSALPHSCPTYLFPTLSFPTPSLSSAPSSSSSAFDLAFSSMASGSNADLISSMPSPDKPLMPSEQTPSSSTLLSTSMAAMDTMPTPSSHVETPQFSGNSIEKIEEAKSLTELLQREAHNKQVQRASLSQLEQTETTTLVHLHSCLERLVAAVEEVGFAVPPTARTLGALDDLANFLRSNAQSIRQEIQSMEISAQMLSVADEVTAANTPTQPKESAFIEITALTQQLVALQLESSQLIQKKEDLAKQLLNRKTASVPSSAPPSGTGKGMDFLSVAPMPVPQDALRKTESVATTAPANNAFDFGSLATPPPVAATTTTTQPQDDGASFDWGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNV3</accession>
    <name>A0A8K1FNV3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNV3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="104" mass="11235" checksum="597082D948C43787" modified="2022-08-03" version="1">MGKNTGDTASSAHSDWVDADNVDRAQLVDPAQTCGSARDSESSGIRDLAFYGYEELVLAFSTTRISATLAIDLVVCARKPVHTRSNLIQKRVVYRSSGVNDAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQF7</accession>
    <name>A0A8K1FQF7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQF7"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="1">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="130" mass="14940" checksum="61BFFD534BC209CB" modified="2022-08-03" version="1">MASVQRFLRMSAAEAEAAMKPHLVEGKWKQPLLSRRKIAMVKKHAEQNGLVGQWIEGQGGWLEGWDRPQKHHVMRPPKGHLHQRNEFERVKKVQAALANMPTKIAEHKKAVKQAKPLKGLDKWLNESDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQT5</accession>
    <name>A0A8K1FQT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQT5"/>
    <dbReference type="OrthoDB" id="162896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431617" description="Protein kinase domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="420"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="705" mass="76651" checksum="BD84852E10D2661D" modified="2022-08-03" version="1">MTRLPLALTAVVTTMASVTSAATCAKSGIVTPGAITLTVDPSLADSVALVVNAKCQEIQVEAKASEEVGELRVTANNMSIKVVESYPAVQSLFLQDNAITTFKADGTTLKEVDLTNNQIASLDDFKFPSSVQRLFLDFNPVESFSASNFPANLKELYFRKSSLSSVASYRFNDNLQKLFLNGNQNLLSLKGLVLPDNLQSLECSDCGIDEIVGVTFPDSLRKIVITGKTISSFDVRESDVPNLKKMQLQMDVATISSCSNENAQVTPITDSISACVMDDTSFAIAYPIKPKSVVTTAPVAGSTPSTTTPGAPVSGGSTTNNEASTGGGSNTNTITIIVGVLVLVAVLVGAAIGWFFQRRRRSRKDSMNGAIIEKGTGTETKTLYEGMDAYNSSSVNSGFLPNDVRNDSDLIPYRLPNDAIKIVAEIATGGFGIVYRATLYGQTVVVKQVTPIKANSPEILRRFMDEIRLYARLDHPKIVKFVGLSWTNLLDLSLVMEYMPRGDLNAVLKMNHRMSRGRSLFSWFNEQSEPRCKALLAQDVAEALVYLHSFASPIIHRDLKAKNVLLSENFDAKLSDFGISRESAEETMTGGMGTTAWIAPEVLQGDRYSEKADIYSFGILMCELDACGHPYDRNKTGVDSLSDAKIAYLVSTASLKPQLDEDCPPAIERLIMSCIEFDPSKRPTALELHYNLRKIREAALQSGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQZ9</accession>
    <name>A0A8K1FQZ9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQZ9"/>
    <dbReference type="OrthoDB" id="156065at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035447602" description="Expansin-like EG45 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28760" checksum="2F0FC9895B4A90C4" modified="2022-08-03" version="1">MHVFAALSTLLLATNAGYAIGHKRSAGQGYSNGNKFSGVARSASTGDFYPNKCAYNDFSSVIVPAAESRFAYVTSAYWSKDLPCGRCANVTVAPADDPQYAMPNSTVTVMLISQFDETCTSDDGTECVGDLLLSTQAYREMLNGGTGSRFDVNWELVKCPDDFVRGGVEFAFGDGTSANMLTVQPRNFHGQIASLEVKFDDGSRYPFGAPGQDTTGSYRMVLAPKKDGLDFSKPFTLVATQAISGYSIEVKVDELPEASLVVVTDAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS83</accession>
    <name>A0A8K1FS83_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pantothenate kinase</fullName>
            <ecNumber evidence="4">2.7.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005776</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the type II pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS83"/>
    <dbReference type="OrthoDB" id="275583at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24122">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000025">
        <property type="entry name" value="pantothenate kinase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF30">
        <property type="entry name" value="FUMBLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="50738" checksum="FD292E8393465CFA" modified="2022-08-03" version="1">MPLDALALERVLLTSSFLVFSSSVALLCCRRKKARHRLWRQRVTFKKISKHSDLGQCFGLDIGGTLGKIVFFEHRESSSTATNPNASSPPTTTSTTGAHGEHRRRRRAPSLDQAAGEMTKFLHENENIGATGVQDVRLRVYSKALQGVFHFIRFETRYTQEAVELIAAHGLNQSLRSIPCTGGGAHKYAPYFSEMAGIELEKYDEIECTILGLNFLLTTLSDEVYTFEDVDAKAMAASRMKVIQYDMDEGVYPYLLVSIGSGVSVLHVKGPNDFERVSGSSIGGGTYWGLCRLLTKCRSYDEALDIAVNGSNYNVDMSVGDIYGGSYDKFNLPATTVASSFGRMMTTPRENVTDADIARSLLVMVTQNIGQIAFLNSCLYKTKRIFFVGNFLRHNKISARTLSYAINFWSKGDMQARFCKHEGYLGALGAFMRNAELTNMHGEAFATMMRGEFQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2M3</accession>
    <name>A0A8K1C2M3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013186</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="153118at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="709"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="761"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="841"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="949"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="82"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="398"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="711"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1044"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1285" mass="139501" checksum="060DFE9399AC3380" modified="2022-08-03" version="1">MQREDDGVVHASLSPTGASAQYQRVATPPAAVVAVSEAKLKNSVDPTDSEDDKEDANAKKNNFTFGQLYRYATTGDKIALGIGLIMTGINGALFSCMALVFGDAITNFQPYDADGVNRSALYFFLIAIALFVTDYFSYLIFHSTAERQVKALREEGLRHMLYLDITWYDKHDALQLSSRLNGDTVKIKDGMGQKLGDCIRLVVQFITGYVIGFMKGWEMSLIMSAVMPCIAISMAFLIKTLRTRTEWAQKIYAEAGAVAEETLGSMRTVASNNGERRAIDKYNVRARKAEEQNLALIRMAAVVLGVFFSSMWLMYASGLWYGGHKVSEGKSDPGKVFSAFYGILLGSIAMAQISPNISAVAQAKGAAAGLYEILSTPSAIDASSVDDGIIPGTCSGRIEAKNVDFSYPSRPDVPILSDYNVEVESGQTVAFVGASGGGKSTLISLLERFYDPSSGQIFLDGHDIRTLNVQWLRSQIGLVSQEPVLFATTISENIAFGHPGSSRMDVEDAARLANAHEFIKQLPQGYDTLVGEKGVSLSGGQKQRIAIARALVRKPKILVLDEATSALDNVSERTVQAALNSLMTKTNMTTLVIAHRLSTIRHVDKIVVLQSGAVAEEGSHNDLMKLPDGIYRNLFTIQAGSDNSAEGDDELAAASGIEDGVAATRLSRHHSDVSDRASQTLNNADIDSELSPSFTIRKALSLCRPERKYFILGSIGSAIVGASMPGNAILLSGILSSMTERYMLFQQTGDRTYLTDLYDKIQMYGAIYIGGAVIVFVSTAMQQYCFKYMAEKLASRLRDYHFTALCRQDIGFFDETKNATGALTADLSTNATKVAQLSGEALARMIQAAFTFVAAIIISFSLGSWLLTLVILVAFPFLIIGQAVRMQHMKGEAGATDELAESGAHASQALSNIRTVVSLGLEKWVINEYGELLLRPVAQGTRAAHINGLALGFSSFIMFAVYSLVFWYGGKLVHKDDITFQQLIRTLMAIMMSAQGIGSAASWIAESDNALLAGSSIFALVERKPSIDSFADEGTRLNKLNGKIEFRDIAFRYPTRPEVTVLRKYNLTVEAGQTVAFCGPSGGGKSTVISLLERFYDPVRGNITLDGHDLKTLNLRWLRGQIGLVGQEPTLFVGTVAENIAYGLETQPSQQEVEAAAKMANAHDFIANFPEGYETQVGNKGEQLSGGQKQRIAIARAILKNPKILLLDEATSALDSESEKVVQEALDKVLSLQKRTTIIIAHRLSTIRKADKICVVSDGHIAEQGTHTELLALNGIYARLVANSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2V3</accession>
    <name>A0A8K1C2V3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2V3"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044636">
        <property type="entry name" value="RADIALIS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43952">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43952:SF75">
        <property type="entry name" value="PROTEIN RADIALIS-LIKE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="169"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="447" mass="48947" checksum="3AC6903599D6C037" modified="2022-08-03" version="1">MNEQRAERQDGAATADSQQWRKEEHLRFMKALELFGLDPSGDAWQKITAYIQTRSIEEVRLHGRRYLQQLMHLQAMETPPLQSMDSMRFDLSALSNQNDLNGPNQTNECAQSTKTKNSKGKATNAQNPLSVAALAAANAMSVQRVKVEPPPLVVGHSKKPPVRRTVRLWTFQEDKIFEVALAAWLLTGKPYSWPKLATNLPGRSAKDVRLRYEQLVEDIARIEIGNEPNYPCEYSSPGSSVASPSQLVNAMSMSDSPMSSPSQRPPHHSGLSRRISPPPPIQVSPAKGKSSFVLDSPSLFSDPNSSTRNRVASSLGFMGSGMLSPTFLDFLAGEDKPQNPASDASSASVGRSDTPPSLFSMSGPLPSPLGLELLTPSSRRWLTPRGFSTTPRIWQEFLSDDFKLEDKVKNSSDRTGSCDSSSKNSKETVAKASEGAKPTESPTKSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2X8</accession>
    <name>A0A8K1C2X8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2X8"/>
    <dbReference type="OrthoDB" id="159655at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="28315" checksum="C3E91F24825E89BE" modified="2022-08-03" version="1">MLEGQTVSISIGVSVDGHQGSSIVLPRGHELLKHLEALLPAITKKAPATPPAQAHQDAMVALATLAQQSTQNSPVRPSSPHYDSCSSSTSSQPASSGPKTGTRRRRAGTAVQAGSKRCQIPDCDKISVSRGLCRGHGGGRRCQHPECSKGAQSRSDFCWAHGGGQRCEVKGCMRSRKSKRYCVAHLTWENYDRQVLAPVSAPATYYAEPPKVLMPRVIAPAVPEYVQPQAKLPSLRQALQKNQCINAYPAPAAPMCYTPFVHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C380</accession>
    <name>A0A8K1C380_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">THH1/TOM1/TOM3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C380"/>
    <dbReference type="OrthoDB" id="63779at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040226">
        <property type="entry name" value="THH1/TOM1/TOM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142:SF3">
        <property type="entry name" value="THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142">
        <property type="entry name" value="TOBAMOVIRUS MULTIPLICATION PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="37163" checksum="D3F48BFE80AD560A" modified="2022-08-03" version="1">MADTSAPSAAPGAAVSDAPLIHLEFQYRQVDTILAVAYGGACFFAFWAFMMHYQSSSRQVATLGFYLLMGLAALTRVVWFATPYGVMSVTMEPPLLKMGDDGWINFLVAEAVELFGSYLIYSIFVLIVVFWADMLRRLFTQDNVRYHPLRLFFIVLSIVLFVQGLGFAIFAAKKVDSYWLMLYDDILVALLSFASLVALTVYSYRMKTVLQAFLEVSQIDTTDRIKAVNWATSICSVFLVFNTIFVSYSIISIASYHRVDMMLNPKSWWIFVASKHLLEVCVLYFLLYSLWGKSSDDEQRKEGYEQIPDVVSDDEAPVIASTTPKRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3P1</accession>
    <name>A0A8K1C3P1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Arsenical-resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008511</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3P1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="41901" checksum="A68A698F40FED4D8" modified="2022-08-03" version="1">MSDRSLVSQLSFFDRFLTLWLLLAAAVGFGLGQLDAIQSFIESTTVHNTNILVAIGLIVMMYPPLTKVRWNMVHRVFADWRLLLLTTFQNWVLGPFVMFFLAAAFFHDSPGYLAGLSLVGCARCIAMVVVWNSLAEGDDEYCAAIVAVNSVITIVLYSLYASLLLNDLPDAMNLTTSADITVSMGEVAQNVGIYMGIPFVLAVGTWYWLTKAKGTEWYTTRFTPKIGVCTLAALLFTVLVLFASQSEQITDNIDNVIYAAVPLLLYFIFMFLASYAMAYALGGSYAQSTSIAFTAASNNFELALAQAISAFGLKSDPALMSVVGALIEIPTMLALVYLALYFKKRFYHVADADEDATSAASPADAPYEQLQETSKPATMTTSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4Z6</accession>
    <name>A0A8K1C4Z6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4Z6"/>
    <dbReference type="OrthoDB" id="90974at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="16670" checksum="4E95E36909065B8C" modified="2022-08-03" version="1">MAPSMTTAFPAHSDLGAMVQRQQRPLKDPYAAAAAPGTGLSRRKVAPCLRKISAYNGGSLIPEDAEEYSPTDKGRYTLKKKLSFADQHGQQLALQHEFSRWDAPILCNVKLLPEFNTVTPASRPVEDVPSLERQRQQRPNWPSMYHARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5H3</accession>
    <name>A0A8K1C5H3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5H3"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="664" mass="75188" checksum="82DD0A7E450D921A" modified="2022-08-03" version="1">MSAPAAAQGGGGEENGKVRDLYNALRTGEHGVSFEAFLCELYFLQHRTFTLFDIKDAFLSSTGTNERFLSYRDFQYALTKTSRAKYMERDDLDCSNAELMVRLLDEITSTKTKSEDDEARRIDSIRHQITKRGVLDVLEIHMRKLVQSFQLYGKDNVVTKQSAHHALDTSSAITINGFVDFLNAYFEYEAYFSFKVLEEMGRSVAAAFSGMPVDKPKGSDMVQAVEDDVELIFPQFIELFCRTAAHFHTRSLEQEGAQLRRAIESCRLEFSIELLMEHMKIRIFDNQDDSKSNTKRTKKVENRSSPEVVEYEEGIEGLSLEVDPDTSMRSMESILQELRVLLDNGNTIGTNNSKRTRSRSQSMLFARLPPRKPIPGADRSVPVSSQFDDDFENERVWQPPDVTLIREVIAPPSLPSNILKRLQYALTYQNSNQFNMALGALHSCRKQYQQWRGSVQEETEVKVYFSLMIASVYDSARKDLRAMAMYLEALRHSSLLPLQHSGRALVKSCLGCILYYLGELPLARKCHERVLFLRKSNPACGEEHVDTATAMNNLACCLSQDQNGVAIEEAYLLLKASKRIYLETFGSSHPRVELVTRNFERVLDSQRMIVVDPVGALARGEYIHVIPGSRFQIKALVPVEKPTTLGKKKKKGAKGKGKGGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5K1</accession>
    <name>A0A8K1C5K1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5K1"/>
    <dbReference type="OrthoDB" id="10261904at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="93"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="304"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="521" mass="57903" checksum="75B24E1A6167790B" modified="2022-08-03" version="1">MSVLFGKRRRAESKQTSVHEASVVPAFRETKQQKAPVEDEDDDVVTMDKVQVDGTLAPMPLVSFLNLGLDPWIVKKCELVGIRHPTPVQANCIPPILQGRDVLGCAQTGSGKTAAFALPILHKLSKDPYGPFAVVLTPTRELAFQIADQFNVFGSSMGVRCAVIVGGVDMLKQALELQERPHVIIATPGRLHDHLLRPNPPNLALIKFLVLDEADRLLDVSFAKDLSFIFDRLPAQRQTLLFSATMTANLDRLEEMSLTNAFRFDATPSIKTVTTLKQFYLFIPAQVKIAYMMYLVSLLNPTTDEDESVKKPTKQRKIKANGKSIVMPTVPTSTRPMTSMMIFVATCKMCELVGEIGNELGTKCVTLHSMMSQNRRLAALGKFKSGVSRVLISTDVASRGLDIPEVDIVINFDLPRDADDYIHRVGRTARAGRKGQSISLVTQHDIALLQNIEAKIGKKMDDYEAQAPEQDVLKLLNDVTTATRVAKMRLAERGFEDKVQSRKAKRLEQQEKKNLKQEART</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C650</accession>
    <name>A0A8K1C650_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C650"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43574">
        <property type="entry name" value="EPIMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="27"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="349" mass="38651" checksum="0BAC964084583F5C" modified="2022-08-03" version="1">MPPFSATISSDNGLPDAAAGRVSQTILVTGAAGFIGFHTCVALLERGDNVVIIDEVNDYYDVKLKQSNLDHLTNTYSADRVKIYIGDLCDEQLVRRAIKESKPTSMIHLAARAGVRPSIDNPLLYIHSNVTATTVLLEACRQFGINRFVYASSSSVYGGSQKTYFSEEDVVDFPVSPYAATKKSCELLAHTYHHLYKIECMGLRFFTVYGPRGRPDMAPFKFMDRIARDIAIEQYGDGSSSRDYTYIDDIVQGVVLSHDKGRGCEVFNLGNGSPVFLKDFINTIESLVGKKATIKLLPDQPGDVPRTCADVSKANRLLGYEPTTPLAVGLAKTWAWYKEFYNPQVEQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C673</accession>
    <name>A0A8K1C673_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aurora kinase</fullName>
            <ecNumber evidence="13">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_006797</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="13"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C673"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="111"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="240"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="10">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42294" checksum="89A57C1FFE325F8E" modified="2022-08-03" version="1">MVVPPARATSTVRLAASNNDENASPPRAPRSAPSASSHGYQSTRPTAKAATTSASTRTARANPRSALQERAANAPKSAPSTRQPAQVRQANAPGAPQQPAGPPRAWTISDFEIGRSLGQGKFGQVYMAREKSTKTVVALKVLVKEQLRANGVAHQLKKEVEIHSRIRHQNILPLYATFQDETRVYLVLKYAGGGDLYKKLRSTPGRRFSEKEAAVYVAQLVSALDACHSQHVVHRDIKPENLLISDQGELLLADFGWSSANVTNANRRETLCGTLDYLSPEMIRGEKYNESVDIWALGIIMFELLVGKPPFEAPGQDETIYRITDGPLQIPPYISPAAQDLLHRILRKVPEDRIPLRDIKTHRWFSHLNIRQRMALRGSPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6F2</accession>
    <name>A0A8K1C6F2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6F2"/>
    <dbReference type="OrthoDB" id="78192at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1059" mass="117076" checksum="8A3451C7AA59F672" modified="2022-08-03" version="1">MARDDDVSETPRRGRGGGYDAQMTTAQPYAVVYGAEDGANGSSGAKRKRVKKNREESEWMPPPPPPPPFAQDHAVMMNQMHVPTILQNNSHHPMMNYATANATGGTAASATTVFAEAPVIQSFAETERKRNATTQAQESGQQVSNSGKSAGRASVSQLGGALGPNATSILGLFHPDAEKARRFGTSHDSVVNGEQSSKRRRKGESNDRSTRSSRRNRDSVEGDQVHYDMLRFGVDSVKLVPQGLADRMDARMKPDFVAHIVSIHTENWLRRAGFGHNFVPEITALLTAYYPCTYPTILDEIVAAFVFKRPELCSALLKPMIEKFHKTGESASPTRYPVLESFARICNPTMLLNSRTEESHRHVTACSTLLRYLFEQNTEKFMLSPWIASCAAACGPDVLTTMWKVLIEACLQTGGPMKPRRAKWNVEDPVDQIFELLRAERQTVRRDEVGDCKLSASLLLTLVTEDYKDMLGVPFACEAFEIFFTHASVEASGSFLEKWLEAASSDRDIESAWLSIHQTLILGCSRLSVKKTHWFTKHVIHFVLSRSSLKQYHNWVKDVVLYNAALVLGGVDKSEIDEVVQTSKGESSDGSADSKSTCVGALGSNEKHSEDDVLVHLKALYDIIDSSCAGIGFIETWMDSWCSDDAKVLIPWSYVWGVSQLSLEGKVANNLRLSSFADHLIRKYLRGVILSETVDTITLARIHKVISFVLRSSHEHALPFLRVILDNFATKTQLSPKSNSQVQALVLNVTASIFAQHSSTRALIANKSSVNALSKVLQLVTQRDATGALIRKILCNGRLVRVISDFIKSAKYSEANTVLDIVVRTLRFEGEQVAVWSDPMFIQAALTLVYRVKPSTTYNSVIVIESLSRCSPKSATAVLWCILRLCTLYCCGCSPEAALIEKATIRSNAIQLADMASQALGRMKTLPSDVLLFIQQHIASCRLHEARWNYFLMQFVNRIVQPAVTNESVALVRFIISPRADIDIDIMRLQLLNTFCNMLASTSDSASWRDGAILVTSNQLRASLRDVIANSTCSTSVALAESISRSSFEVKKLLDGCGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6X2</accession>
    <name>A0A8K1C6X2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TFIID subunit TAF5 NTD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6X2"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="9">
        <location>
            <begin position="169"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="618"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="703"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="745"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="787"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW57565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="909" mass="98805" checksum="E14EE230817F9BF5" modified="2022-08-03" version="1">MEPAASLNMASHAALLPPSTLSMGVPAAASPFQRALPSSELEIAASDASENAGDAMKDGDPMPLHTVENVMDQLMMQYLAKRGYKVTLDPSKHGEDVEMTPVDVSMNGHLNGAGVSEADKRRFLGFNDASRIPDAHENVVTLERYATELGLSTESCAANHILFYGLTNGDPTKYLDAYSALVDWICNSLDMYKYELHAVAFPVFVHSYLDLMAKGYVDAAKTFFQRFSSDHMRLHVEELRQLSLVFSPEHVRTNEYAQQVLHSKFNVEMSLLSFELLNAFLSQEQLFLILTIVNERINLIVTSNQPGIQIQQLEDVSISAEGIASMQLRAESNGYMDSDDVAMVVASSDQPNESEINAPLTSGEYNLEYMVEAAGGHGTTLADLHAIRVNWGVLPARKLQVRPDNDDGSATGDGKADGNGTNGSTAASGSGAGEGGAGAADGDKKGTGAADGASGDAGSAATKGGDKSGKSEKATAEAQRKAKRARLPTDPELDRRKSELEIMGPLPDRKNAFNAHILERLVLRQPAEMKALAMEDLRARATLNKNNLPSALCFSLVNSGAHINNMCFSDDVTMVGASCDDGSFRVWRNDDQPLGTARGSTYQGDMTETDEDEKTAVLRGHSSAVYGASFSPDNRFALTGSADSTVRLWSLAAKSNVVIYRSHEGYPVWDVRFGRYGYYFASCSMDRTARLWSTDHMTPLRIFAGHLSDVDCVEFHPNQNYIATGSSDKTVRLWDVQTGKCLRIFTGHFHGVKALAFSRNGRYLASSGDDQYINVWDLQAGKRLETLVGHKATVTSLDFSQESTILASSGLDSTVRLWDMQSIVDKPVHSVFEAEQPIYASTSTGVSSSISSAVTRPVQVVRPASLQDAPASRFMLKTLRSKQTPMYRVQYTSRNLLMSGGVFQPKIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C736</accession>
    <name>A0A8K1C736_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C736"/>
    <dbReference type="OrthoDB" id="100116at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="1">
        <location>
            <begin position="29"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="30357" checksum="7A7DAC51A25B74B4" modified="2022-08-03" version="1">MTDPNHFEDTEVVDVMTLETAFPGHIYGKYKRATRFFLDWVLRAHSATSARRAHDSASVQELNDVVMELVTQPKTLRPQLRKELPLALAACQVVITLREHVARFFPFKDASDTKDTHAYFLDRLKKWHTSLTALLTTCSSKGEQEEEFEVHFNNYYEVLAIPEDFFPEVDTIDIDERKTSSPSDAERKQLFDEAFAHSLKMDMSFFLMELEELSDAVYKVYCDVKFQKKTLIEASAVVKVAIQCATSALRVSSCDIHRFATPWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C759</accession>
    <name>A0A8K1C759_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000131">
        <property type="protein sequence ID" value="TMW57663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C759"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="29127" checksum="4E8A68EC388043AE" modified="2022-08-03" version="1">MRKHATALLNVFDRSSEKGEAIDLVKIFNSFTIETFAEMGFGIEMNCLDSEEEHDFQSAFDSAQRMVVLRYQRPSFVWKLQRLFGIGAEKQLKQDIKVIDDTVFDIISKALANRQNQKATDTPNLVSIFLDRAEDAEDEDGNIDPVFLRDMVVNFVFAGRDTTAQAMCWFFLNLSKRPEVAKKLREEIATMIPELVEGKIKVPTMEQVQQLTYLEAAIKESLRLYPAVPTTLKLVEEDTLLSDGTFLRKGWFAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C785</accession>
    <name>A0A8K1C785_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_014357</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C785"/>
    <dbReference type="OrthoDB" id="100546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0140">cGMP</keyword>
    <keyword evidence="13" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="19">
        <location>
            <begin position="111"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="19">
        <location>
            <begin position="232"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="19">
        <location>
            <begin position="353"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="525"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="20">
        <location>
            <begin position="786"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW57754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="844" mass="93487" checksum="7F2CC4A2D88504D4" modified="2022-08-03" version="1">MGCVHSVPAASKGSSTNADNNGKSSFRTKSGRPARTLSQHHTPSQAQLAEGVLSEMLRSRRRSIRSSQDYDADTIETIAQLSAMGSDPAHQSQISEPEQDCIVQALQENVLFSCMNHDQLLSLARLMSIQIVEPGETVVTQGEIGDKFFVVRSGRFEVVNAHGDVINRLSAGATFGELGLLYSAKRTANVIADAKVRGSLYTLQGSFFRYIAAKHSIETFQSSLEVLRKVPLLTPLTEEQLSLVANSAQPLLYRGGDVIVHKDEPGSVLYMIHSGTVVCTDIGNGGATLELSDGDFFGERALLASEPRAATVIAKTDVRLLAIDQRTFQLVLGPLQTLLQETRVWRALESVSVLREVPYPLKKKLLAAARVVQYEENHVIFHQDDAGDAFYIIKDGEVRIVQLPTRNSETTASVSPLGEQEARQADATSSLSSIQLSLSPDAKPLEVARLGAGDMFGEMALLQQGPTKRSASVVAASRVECIVLERAAFEQICASARDDLEELARRRTLENYERSFVLSLSVETLEKLGVLDVGSEGSVIYAARHTPTQRIVAVKEVWKSRLEHNQHVTSSRREKRLLAHLESPFVLKYFTTLQDERKVYIVTELLLGGKLFQRIVESSGRSICLAMDHARFYTASCALALGYLHEQYIVYRDLKPENIFLDHLGYTKLVDFAFAKKLAGKTYTLVGTPEYLAPEIILGVGHGLAADAWSLGVLLYEMVMGESPFATKDQDHLSICRNILLERIRFPEDADENWKELVLSLLDKTPEKRPSLVPSLHALAGFDWFQGFDWNALTHRTMPAPWKPTATSEQDVTACSFVKLSNEQLSDLEAPWNEIEPAWSWEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7I2</accession>
    <name>A0A8K1C7I2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7I2"/>
    <dbReference type="OrthoDB" id="166900at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="191" mass="21746" checksum="CB68A54C9AD8D9AF" modified="2022-08-03" version="1">MEFARNVALMPLALLINFSLFQYLMGMYFARRGEARTMLLLVCAFISFVAIIPFSHPNRDIFSGLDSMSKTAATLTFLVQVVIIGRDVTKKVKIRSVYLMTYVSEVLILLEIVIIIATIGELVDHGYRSAILMDATEILGDISLWFVFVFQFYYISIAKGFKHMIQTTRVEMFFILSSQLTITRSTVSQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C874</accession>
    <name>A0A8K1C874_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C874"/>
    <dbReference type="OrthoDB" id="106293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47157" checksum="3C8C36C3113EEF9E" modified="2022-08-03" version="1">MDASEWAELESFLATDESDYATLTAALAWVDDSTLPPLPQTPGKPFSMSPSASSTDTSVVSEPTKETPVKTRKRRHNRRDEIQLLHATARQLEARLAFLKERATNGEVATAAAVDDSTDKTNQLWKRVAGSQLAALSESERENARLRAMVKEQLSLIKGLERLMMKKRSKTFSWCPEYARSSPGVDPIEDAEVEKDMHKSIEDMLSNVDRILADERLQGDLDEPVSFVNVSSDDHDHPVVESMHTRMFPFAYQAAANALWTMWTSSHLHIMPSLRRKDICVDGDTARGILEGEFMLENTMARFRVKMIGRRVIQDDRVIMPAVALIDPMIKVDDTPLSGVYLRVRVCNIFRNVPGDEPVTSRVTHSLCTPMTFGDHEGKRRGIGALTNLVLQTSGVGAKMNNQILENHLLESFAKLGLNDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8B3</accession>
    <name>A0A8K1C8B3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Survival motor neuron Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8B3"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20635">
        <property type="entry name" value="SMN_YG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23853" checksum="FD889FF7C5FDCDCE" modified="2022-08-03" version="1">MTMSSSEDDASIAEEKWDDMAIVRAFEDALNGRQNRSPSRVKKPSKSSRPKRNGRKASVASVTDAYSTQETSHQAPAYGAAVPDATQYQSQEDLYQAAYAQAYAHLQSQMQGAGAYAYQTPMTHHTAPPSYQAHAPPQFQPFSHPQQPYYHGAPTPGAPWTPGMQPPSQWAAPPFPSVPGQGSQDDLANLLLAWYQSGYYTGRYQAMQEMRARSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8E8</accession>
    <name>A0A8K1C8E8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8E8"/>
    <dbReference type="OrthoDB" id="101428at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="23268" checksum="C7FC6625CAD6FC0E" modified="2022-08-03" version="1">MMAVIIGMPTVLIDTQVRIVIQRMQTLTFSIVGTIGMAVAELAFRLVKVALLKLQIHRREQRAPITPTLVNSMEHQTRTADDWKHRVQTYHVAEVYADMLAEYIAAGSALAIVGFYWNHPKYLLHRAANTENTDLDLQYGTNARQLVVFATQIGIQIVVDYVSCIVTIRNGIGFGAITRYATFISAVFITMASFNMQISALMYLDPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9V2</accession>
    <name>A0A8K1C9V2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_006968</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9V2"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="29"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="45436" checksum="FFC8C42FC1841100" modified="2022-08-03" version="1">MVFLRRLLANTTSAKNVALRGMATFDRTKPHVNIGTIGHVDHGKTTLTAAITKVLAEKGGAKFTSYEDIDKAPEERARGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAGDGPMPQTREHILLARQVGVPALVVFMNKVDQVDDEELLELVEMEIRELLDVYEFPADDIPVVRGSALAAVEDRDHDIGRDAVLKLMDEVDSYIPTPTRDFEKPFLMPVEDVFSISGRGTVVSGRVEQGIINVGDEVELVGIRQSSKTTCTGVEMFKKQLDRGQAGDNVGLLLRGLKRDDVLRGQVLCKPGTIAPHTKFEAEVYVLKKEEGGRHTPFFTNYRPQFFFRTADITGSINLKEGTEMVMPGDNTAIDIELISPVALEAGMKFSIREGGRTIGAGVISKVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CA76</accession>
    <name>A0A8K1CA76_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CA76"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW59589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33668" checksum="72676802D7FD9757" modified="2022-08-03" version="1">MPPIGSTDSNSTVSAIQDSVVDIADHTEAGYIVMTEKDYRDPKTSHFRVQNQHLRECLAEFYGTFIMMCFGLGVNNQVVLSKDKNGTWLSGNMCWGIAIMLGVHCAEGVSGSHINPAVTLAMAAFKRLPWRKVPGYMLAQFLGAFVGAVVIYILYYPWFDVIDPDRMTTQDTFATYPNDNVSNATAFYTEVLATAMLLMGIFCITDQKNRPSTPFGMPVHFMFLIWGIGMAFGLNTGLSINPARDFSPRLFTSMAGWGSKVFTLRDYYFWIPIVAPFVGGIVGAGSYELFVEMHHPTVSTPLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAQ8</accession>
    <name>A0A8K1CAQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAQ8"/>
    <dbReference type="OrthoDB" id="72677at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55374" checksum="ECF5653182F752A7" modified="2022-08-03" version="1">MDEELLALLAAEEAARATTGLWADSVDPLDEALLELQDAPLLGESNAGLPWEIGAEGADSVISKPVDDLQTSSESTSDVGSTVGDSSNANSPVRTTYQRRKAERLYLRQKVSELEKELHALKQRGSSEREDDNASEPANGSDVTVAVATFWQRMAKRQQEQRQRSIAENLRLKDLLEGQIKLAKELELMLSKRSESADKDTDELLCPARKRARLDVVATPFAELMESFDERYTQLELAWKASGLDAKKTTFQTVQVRPISTSPDDADWYLVFLDSRVLPFDPALTREVAWRSLNTPRIELEKGFFETVEFTADVVKARGVMAVHLRHAESTITSQLAMRRYLDDDTGRSVFVWSVSSRIEGGVLKQRVVTVVEDGWTLIEPVPETSYSIVQACGHIRSDVPAETDRKWRESVGLLTDVSLAMYHQNLSGMFERMEGMLMQESQTYQTVHCGVRTMQTRPQSVDIQDNSETYCSLAKCGQERGSRGEICYVTLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAU1</accession>
    <name>A0A8K1CAU1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_007182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAU1"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="54122" checksum="43456AC061359BAD" modified="2022-08-03" version="1">MTQDTPLKGSNHIEDVQRITRRIDAIGERHPGVMFGLSWYYIRLIFLTGIGWAMDAMETLVFTYVGGMIKEDITYGPHQGSFLAGAVFVGSFIGSFMFGPLSDKYGRRPMFLVTLMIFLAGFALCGAAWNITALTFFRIFAGIGLGGELPVVSTLVQELSPKKTRGKIIVLLEAFWAFGGMLAIAMAFGVAPHTGWREMFYICCIPVVYGAVVRFGIPESPKWLASVGRWEEAVAVVEKIERSHGLEPYDEKKDVDSVPSVTSTYQLPESHLARIKVLFQPPFVVRTIVLWTLWFGISMSYYAIFIFLPTLIAAKGVNINENWERILLITAFQLPGYFSAAWLVEKLGRRYTLVLYLFGAFASAIALAYVPTTTVNVIASASAMAFFMLGAWGCVYAYTPENYPTAIRGIGAAYPSGFSRIGAFSGPYLCNDMLEWGMTLESILWVFGGVLVFIAAVVLLFGYEPQGKNVEDYGDYKEGFQEISTPGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB54</accession>
    <name>A0A8K1CB54_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB54"/>
    <dbReference type="OrthoDB" id="152055at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="597" mass="67757" checksum="C81D0171F14D1A77" modified="2022-08-03" version="1">MTNKAKPKKRATIRKIFLLLTNVASTVLTLLTGLRENPVIVLVSGRYDAVRSRMREGMISYGIVEDDVVDVDKLPDLKHLYESELHEYDGRDAQLRRGKGVRRTQVFFYSISAKRCGIINFRPEWVDQCVQDQQGNATQCHEYILNNFDDLKQDRSIQAGVELDFGEPGFPFLKCKGRPQGYFNFNTDLVVHQSYWAGGKYHIEVQTSECLAQPLLRDSKWVWGLFQVEQADQAANVVVALPKSGWFGTIVTFAYGIVSITMIGHGILAAFVRSRAVPYLPDSLRSTREHTVAKFLAPFMSVTTLLAENENTIITFKGSILMASDVWMNHWLYITLSVLDAVINVRMTYVILEMGTWMLGKKANFENFIFLCSALTRITWVMCLAHSITRLFFKFILRSLKTLKVVRSNIRDKLEWYVDATALFMSYKIYNLLLCVLLYLFLEFHGGTTFMKQQPWYKQGMYGGNQSIAQFWGNEIICDFFVMLSILTALGWAISVAILQTKYRYLANNGVIRLLQHRYVLVGWDAWTAAQVLGIDPYNPMLVDKDMTLTGCSIGSLLQLLYASGPSGLVHLAGDYLLVDGGFAKGAVHFHYPINAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBN1</accession>
    <name>A0A8K1CBN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBN1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="156" mass="17596" checksum="FA07D22C3E7AADBE" modified="2022-08-03" version="1">MEAVSVVQVLHQVCSLGSKVKQQNETLKSGLELLRDQRVSLQEKLGSGELAPSELLHKCLLKLKDAIEAIKEFQKANVIEQAFKRKSLLRCLKDCEARVTDILATQRFINAESTINRWQGMYNMLDGLAEDIHTLVQTKQVDTRFPEGVVRAGVFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBP4</accession>
    <name>A0A8K1CBP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBP4"/>
    <dbReference type="OrthoDB" id="418911at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="306"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="340"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="395"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="525"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="525"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="628"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="666" mass="72518" checksum="A4D23FC54DB5C121" modified="2022-08-03" version="1">MATPKMEESNSLTRQLTAANEEAWLTMGRIAEMMGDDENTMLAYEKVLSHNRMNATALFAIGCCYEKVEDYTKAADCFRSLVSLNEQNSEAWGHLGYCCLMMNDLTSAHTAYQYAMYNNPMSQKDPSMWYGIGQLYERLGSLEHAQESFEAVLRFEPNFNMALEVKFRLGIIAKQRGDYEGALERLKSVLHDVQTNMQTNEMASDIWTQIGHVYELKDEIQLAKSSYMKVAELNPNNAKPLQQLGWLCLKHGEHSNAIDYLKKAVNIDPNDGKGWYLLGRCYMAVHEFEEAYDAYKHAVTTDSQNPNVWCSLGVLFYQLNQHLDALDAYSRAININPNICEVWYNVGTLYDTCNQTSDARDAYQKAAELGADAQFIRERLELLRARETGQSTIGMAGANAAPGPSEPPTTSPMPTFSTRPTAETNYPAAAGQQGAGASGPPQGTPVVSAGMPAPGGSMAHFTRAVNGEGGMSMPNAPPGKRADGAPGIPTSSAGRNGIEMMRGMSRPGVMPGGMMARGVMVPGMQHSHPQAAQPVPAHHAQAQAHAQAAQHQAQMAHHHAQMQAAHHAQAQGVPPGHMQQGDRRGGMPGRPIKEEGPVGLRYPPMDGERKMGGPGGQQRLAGLNPKNLAPPPQGGPGGPPRRDFPMPMADQKHRGHSSLPPPPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBX8</accession>
    <name>A0A8K1CBX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBX8"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="301"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="490" mass="54259" checksum="CB6D8AB005E210FD" modified="2022-08-03" version="1">MAEEVLACARYGELEELQELLKAVSVDEKDSYVNYVQPDTLNTPLHMACANGHADCAKELIAHGARHIANASGNTPLHWAVQNNHLAAVKALLEGIPDIDVLAQNGFGRGCVTEAFSAQDTEILGVLLEHKSASEERLAEGSGMENAKIREELDETDDEESKSGSNEPKIVQEMVLEFGFDKSLPTLKARELALDWNKDVFGTTAEEDITGVSIWSASLILSRWIIDNADMFANKQVCELGAGCGVSGLASYLYTKASRVVLSDLFEHTIKNLEYNVALNKTTTASIEPEQEDADDEERGCDQCGVMQKFSADNPDGKLMKCGGCRTTQYCSRQCQKKAWKEHKTECKRIRAERDARTATQRSLDVAAIDWAKRETWPQLDGKPSPFDVLIGSDLVYHREIVPVLVNAVDGLLAPNSDAKFIHVASQARDSLIEFKDAMEARGFTCDVQFVPESYKTNPLVGNESVVELFDLHFNEMSDVYCLYTFTRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC86</accession>
    <name>A0A8K1CC86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC86"/>
    <dbReference type="OrthoDB" id="77038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="55985" checksum="A19400A29671E80C" modified="2022-08-03" version="1">MEASAELFDGVVPRFDDADEMDASEHFQLQLQLLAASRGIGMDAALATTKEPGATQPEAEAEAEEDATTEAERVAIRALQAAAAVDPHAIDDALRAHQAEPMTTLVTEADLVGTLSSLVPTADTTSILTVSTTSLLLADNTTSPSLKKPTRRVYRCRADKCAKLAQGGGLCVAHGGGYRCQTPFCPSFNLRTCPDHGGSKRCSITGCHKVAIGPGGLCCTHGGGKKCEVSKCTKFDAGTGHCLRHGGGRPCSVDGCSKKQIRYGLCSGHGGRAKCKVDGCDKYDRGQGKCKAHGGGYLCKMDGCTKKDRGGGFCAAHGGGKKCSVDGCSTPCVGGGRCKLHGGGRRCSVDSCRKWVVQHGKCKDHGGSGRRCSVKDCEKYDQGGGFCLAHGGGFKCIVPECTKKGVRFGRCCAHGGKPRCMEPDCERMAQRRGLCKAHGGATNCDYPGCTRRANNGKRCIGHGGGGTRCKFDGCTKTNRGGGFCKAHGGGKRCTVADCNEWAIGGGHCGQHTLVPTTSVSPVPVTTAVPATVLDAVACV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCA7</accession>
    <name>A0A8K1CCA7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCA7"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="328"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" mass="61571" checksum="4367CBEFE0705419" modified="2022-08-03" version="1">MEQPEPPLDAHSPPPPQVSALAELFLNHNTPRACQLLQETPEELLSEELHSAFACVPWATDAFLHTMTQWPHDTASDKFLAVIDEAIRCVYSIPYLQVSPVTSDLAGIVLVSTFPDCSQHIQLIAFIQTFRVNWPHIQQFGCQLAHRDAIHAVRLLEMLSLLHLLPFEVLIDAAIRQRDLYAVDTYVAHFPAFQRPFVQAIILSDLPDQFVKKRMLMFRFNQSDFPEYRERKLRGSIRYCILNEMYDDALVSIEQNPSLSFFAANFVIERKGPEHPVTRLFIHLAGLGAHFPQVDTSDQEGKSFPNRDDLKPLPGCLSVVDLIGESNIVFVDTQEALDACFKDLLQSDVVGFDCEWKANTSGYRHAPCAVLQLASASRAYVIDMLALRGQDLGAIPLFFSSNEVLKLGFHAKGDLNALRDMLPSTHSSRTLTINRLVDLQAVAKQMVHTQWQAAKSDSDSGSQVNTKSVERSRQVSKGTTVSLATLVQEYLGRPLDKRARMSNWERRPLTRAQLHYAALDAYALVAIYHKMQDEVPSDVLVRILNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL1</accession>
    <name>A0A8K1CCL1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCL1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="394" mass="44432" checksum="9911DA24DEA2EBE6" modified="2022-08-03" version="1">MNWLELQLDDDPETLRAALELIDSAADAPIDAEDAGDHTTSDSVEEKHGREELHEPTQRTSLRRKKEIQQLQHKVTELETTLSNLRNTERGVISAKELTSELVWKDIALRQRKQRCDAETENERLTAMLHAQTVVGKQLLHLLHYTTASQSEAARIAKEPPRDSTPTEEQYRHLDELFAESESVFASERFNTPKPSFQDLRVLKDGTKGMVIDTFAAWVVPFEASQVADALWGSMTHYDDSKMCKSIQMNVETKDDTLIASFTISNASIPDGTYGYYSGTSLGRRYRSDDGSTLIVSMMSGEMVGSTPTSQDHIGALEVQWMRIRPIQSIVETESAPIVQVQLNRQIRLTFPTSHSAARRSIVGAVIELLLLQVEDDITRKQEMVERLMFQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDP1</accession>
    <name>A0A8K1CDP1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDP1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="316"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47932" checksum="6C6E19D4F10CCD52" modified="2022-08-03" version="1">MNKRQLPSHALPNLRLSPSEEQDVITRTNAMVQRALVLEREFHHQGARINEREWKEITAVDNFRVYRPRTPKKKHRFSIDKRRTSTNMISSSGTWHSATSTSTTEEEEIASTSRNFSHVMCAGYLEGTLEDFLFGSFDGDERSWKIRAAYMKDKFADSRIFAKIVRPTPEEPYRFVGIKWFAVEVPAIIDSFLHMRDTFVMESTGMADDEDGVPYAYFLFHDYDHPDLPELTEFGIIRNRLSICFIARQIAPDRIYIHARGYVNVGGDVIKSVGLTVAGVSLASTANSIEASYGKKLTWLMSRHLEQRRALLVNGRGHSHECHACQKPTNKLLSRSSACNVCGFTFCSKCTVHRKVVADVETLELSSKALSFCYPCVIKAKKYHPHEIALDTLVPATMSRKENVSRRKAFSTWVPPAPLGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE04</accession>
    <name>A0A8K1CE04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE04"/>
    <dbReference type="OrthoDB" id="58760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066:SF1">
        <property type="entry name" value="LNS2_PITP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="53898" checksum="BC28EC539C75CCD0" modified="2022-08-03" version="1">MLLRGRVPRASLFAWPRSAYLVPGRTTQCLSTSAGDSSFEQVAHVPRRRTRGQVFTLLVPALEAFYASKGHFLVPYHYPIPSQTSSEDESNTGAIVWPADAHGMNLGRTLHAFMTNKNHHKRFPRVVTSLRAIGFPVDVDWKQYLWKELFMAGLETFYRQEGHSLVPIHFVVPSNDARWPRQTWGHRLGTQVHAIRQKLDALDPIEREDLERVDFSKDVNETVWSEKLLPALETFAAIHGHCVVKHTFVVPSEEPWPRKTWGLNLGLAVNSLRVNRSYSEQIARDADRLNEIGFVWNVREDKWKEVVRPSLEVFAQQHGHCRVERAFVVPSEAPWPEKAWGFRLGHAVNHIRSKGSYAKEIAEDEQLVKTIGFVWDLRQDKWHEMIFPSIEVFVSLYGHCHIHRSFVVPAMAPWPAKAWGFRLGIAVHDIRYENAYADLVGEYQDRLRAIGFLQWVKGDPKRTPRALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CET1</accession>
    <name>A0A8K1CET1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-methionine-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CET1"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1060.10:FF:000002">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050162">
        <property type="entry name" value="MsrA_MetSO_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42799:SF2">
        <property type="entry name" value="MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="8">
        <location>
            <begin position="12"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="19364" checksum="A56EE13A642E8301" modified="2022-08-03" version="1">MAENQNEQTNVATFAAGCFWGVELAFQRLEGVTKTDVGYSNGETENPTYKQVCSDKTGHAEVIRIEFDDKVISYNDLLTTFWSIHDPTTLNRQKGDIGSQYRSGIFYHNEEQHKAALASKEERQKVVEKEIVTEIVPAGVFWRAEEYHQQYLEKGGQCSDKGCAVPIRCYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFB0</accession>
    <name>A0A8K1CFB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor Cactin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CACTIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFB0"/>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018816">
        <property type="entry name" value="Cactin_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10312">
        <property type="entry name" value="Cactin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor cactin central" evidence="5">
        <location>
            <begin position="149"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="4">
        <location>
            <begin position="439"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="562" mass="66839" checksum="643CA7102FFF3F9D" modified="2022-08-03" version="1">MARDEKRRKSSKKHKKKKSRRRYDSDSDASSRSNSSSSEDDRRVVKKQRKQAEKVLASFGYTNETNPFGDSNLTQPFVWRKKYEGGSDASDDDDDKHKKKKKKASRPSEKELKRNQLARVEEIRKARQRREEREREQEEKERLRQEEMRLRDAEQYEDWQQKEEEFHRTQTKVRSKLRIQQRREKPVDLLAKNLLLADHAMQEDEEDDFYRRGVRVETRRPHAIVEVLSMDELEDLREDIRAYLDLEESRNTGKTNKEFWDLMMVVTRDRIRRLRRSQSEASEDVRGRERGAIHDSVNDTIEEMLSGKNTSELDKLKDEVEATIESAATTPGVDVEFWEEVAQQIGVYKARARLTELHDDMLDKLKDLIKQHDTAAASQGDRDRERERSHRDRDPSDLRDDSAEARALEHQEAEKGLEESEEKLGTADEVALEGKLPSWSDKYQPRKPRYFNRVKTGYDWNKYNQTHYDHDNPPPKVVQGYKFNLFYPDLIDKTAAPRFVLEKSNSSEFCIIRFTAGPPYQDIAFKIVNREWEYSHKRGFKSVFERGILHLYFNFKRHRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFB6</accession>
    <name>A0A8K1CFB6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFB6"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27794" checksum="23EA48718C5D213C" modified="2022-08-03" version="1">MSSGERGSNSTPLTLAIDHGAEEIVDLFLARGADVNKSSAYGHSPLSCAAKEGLVSIVQRLLHEGADPTHFHPEREPSPMKGAVLARSLPIMKLLLDHGAKVDAVDTFDLYEFRGTPLDVAVMENLFEEAELLVKEGHADVNFTWGNNKTQVICHAAGRGNVEMMAPLLDHGADVNGGDADYSPLYNAASSGHLAATQWLVEHGADVERLTSNADLFKYCVIEAERHGKMAAVVEYLKALKTESQTELMDTSMDAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFD8</accession>
    <name>A0A8K1CFD8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005054</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFD8"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567:SF3">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="47041" checksum="ED5F782AA3B31126" modified="2022-08-03" version="1">MSRKTSERDALLGNGSTNDDTLLHHHDEPYLVRLVSVVQEIVPLSLFSFGGPPSHLALAHDRFVRTKKWLTDERFLEVLSIASAIPGPSSTQVVTSMGLFRAGLLGGFVALFFWMLPGFVILTAAGVGAQTYLQDGLPVWMSGLAPAAVSLVVIAAVRLWQKAVGDDKVKAIVATASSCVVLATQGLSSLVFPVVMVLGGCTILAGHITGMSIVRIAPDQNTTHNLQKQIGISAVGGALILAVWFSVLIALAIFHPQDAEHHTLLSMFYALYWIGSIIFGGGQVMLPMLLNNFVNQGWVTKEQFLAGFALVQSLPGPMFNISAYLGAVLYGPIGAVVAAAGLFGPGVTLFFGLLPLWEQVRDYEKLKIFLSGVNAAACGLVVASIFLLWEKAVHSNGDAAVGLATGLMVGVFNVPSPVAIILGAVLSFVISSQGFNIGQSDFCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFX7</accession>
    <name>A0A8K1CFX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFX7"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="64105" checksum="A524EDA89FB52EC8" modified="2022-08-03" version="1">MADINKPDEKSPLLKQASNSTSPGRLQPTIKPVEPEYEVDPQVKHVDAVIPLRQELWELSSMALQFSLRQMVRQAMTLTDDAFQGHIGTKQLAGVALAAMWMGVPSTFIQFSIQAINTLCSQAYGAGNNKLVGIWLQTAILFAVVGAIPVMIWYMCVGHFISITMDDEETVYYGSQFAMVMAIGLIPQYIYGACSTYFASQGIIMPATICSALTMVLNIFFNQFFIYGAFGWKGLGFIGSPLATVTSTCIQLTLFLLYTVVWKQYHKQYWGGWTKECLRKDRLQVFLSLAIPMGASSVVDWASATIAGAFSGFLGPNIAASQAVLGGVFGVTNSAVSGFSTSTQIRMSRYLGKGNAFAAKRVLYLGGSIVLGGAVVMLVLVTLLRHDIFKVWSSDPVIIGMCTDALVVFVVCILVAFVRFLLTAVLNALSMAQINLWANNFASWCIYVPLSYVLPITLGWGLDGFWWADTFGEMFKVLILVWGVSRVNWNDAALRAQAAAEADGLDEDDAEQERKQVIAYENEALVGRTPESFRTPSMALTPSTPYHTPSARRRVRSLLERQNSFPAVQNSRMARTPDARMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGX8</accession>
    <name>A0A8K1CGX8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGX8"/>
    <dbReference type="OrthoDB" id="185253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006139">
        <property type="entry name" value="PRK08289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43454:SF1">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE NAD(P) BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43454">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="4">
        <location>
            <begin position="156"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="527" mass="57714" checksum="90E243210DB4FF00" modified="2022-08-03" version="1">MAATLSSEEITALCDQELEQWKQQEEAADLMVPLIGRLYRQRNVITTLFGKGLVHKNSVDIIKQHNYVCKYVGKTMMPADTIVVLTAVTQFAPHARDMRLDLGRTLLLVEDEVKAVIEEEDEDAKQLKIKELGLLLEKKMEPLASPVHAKSMTKPSDVVLYGFGRIGRLLARLLIEKSGPGVKLMLRAIVVRKGSKDDLAKRASLLRRDSVHGPFHGTIRFNEEANAIIANGNVIQIIYSDGPDKCDYTKYGIHDAVVIDNTGKWRDEAGLGLHLKSPGVAKVILTAPAKGNIPTIVAGVNDSAITSEHQIFSAASCTTNAIAPTLMALEQKFGIVDGHIETVHSFTNDQNLIDNYHDKERRGRSAVLNMVITETGAASAVTKCLPSLKGKLTANAIRVPTPNVSLAILNLHLDPEKSQDLTVKDLNTFLSKISLNSSLQNQIDFVKSAEVASSDFVGSRASGIIDGKATIVNGNKVVLYVWYDNEFGYSCQVVRVLQMLEGIAHKRFPDASQVEAIDQALHLTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHB2</accession>
    <name>A0A8K1CHB2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHB2"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042655">
        <property type="entry name" value="LRC72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46759">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46759:SF1">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="502" mass="57594" checksum="DC18A8212305A7C8" modified="2022-08-03" version="1">MAPTQADARVRLADPLAELPIKNFKYVKNCTELYLAKRGITKIAHFEPFVNLEVLWINDNEIEQLDGLDTCFRIKQLYAQNNRIRSLDDSSLRHFKFLQELRLYDNKLRDFPSTLEALGRLHRLEDLDLFGNPIEEEENYRLHVIKAIPSLLVFDRHVITDEERAKAQRLRGDLLGEKRSKSRKKKSEVIAGAPPQTMSGTVKMLFREVKAIQRGREANAKAAAAQEVLEMSKTQQELSSLASHHQRKTKMANQENLGDLDEWELSALEKQFHQLETKKHTGLTRDQLPNLLRYLEDRGFSVICDGVSVVADRHDVLGNLLFGVNAASGQKIAWKDWKRILSSSHLRCEFMQPHILHATSSKHFETASTLQRRLLSISDESTRVKLSQELHILSQRAYHLKSVAEKLEQIPETRESVTPSASSRLSSPQTHDSQLTPRTRFFITSFRRTTSPTVTFHELKEQCAQVNNGMASKYKLHSKDMNKYLLRKAPATSTLVRKDLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHD1</accession>
    <name>A0A8K1CHD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHD1"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="81418" checksum="B5CE6AB67909101A" modified="2022-08-03" version="1">MMRHAWTQSAALLRRQGVSMQSAASVQTAAGQLQFAAHRRKRAGPHRPRHGAAAPPTGPPGRRLRQQDLSHKRPAPLRVADQRIGMLLTRQTPPSAIQRICEELGREDEVELLSATEPKVWNVALQNRLVQDDVDGAKALLQLLSGFAAENMSEQLWNDLLFTLLRQRSSLSREKEVRRLLDTLKRACGAEFVANVIVSTVNGCANIKMFEEARFLVMYHLELKSRVPLPRRIMGNLMSNMQIKRRYEHVVEFASDLMLHKQTTVNQIQPQFWIALFQSCAQTRANPSRFVDQLIVWFDAVKTRPMDEKPQFERVFGAAIQCCVSTGHERLALRCYHAMVGEEEEEEGSNTARVCRPDENIYVNVLKAARALHDTSLFVDVYRAMVRDRVARSAGFGTVIRFCHEQQDVELLEEVLEQAFTVEESLRGRWILPIEQYNDALGCFAETKAFDSAKELFSRVVASPVLKPDHVTMVEMVENYREAPFSDVFELMELFLELDISPNLHVFTSLLATCGRRRLINDAMALMDAMKAQGVEPDVKAFTAAAFIFGTHGHLEGIIGVFREMAARNIEGDGKFFDTIMDGLYEGNGIDMCFSLFQETLAAGLKIPQRMYASLIRVGTRVGLIERTLHIAYNMECEGFPLGSDELLGLIRRCEASTEVKELLRTFILLHAEQPMDSSSPRFSFDVYDEMIDLLGRFSLRDGVSRVQRLAEQAGYSGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHD7</accession>
    <name>A0A8K1CHD7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_009665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIGH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHD7"/>
    <dbReference type="OrthoDB" id="6256716at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044215">
        <property type="entry name" value="PIG-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019328">
        <property type="entry name" value="PIGH-H_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="4">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW62172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="180" mass="19767" checksum="05BB1C3B2CDFB805" modified="2022-08-03" version="1">MGGQVDLAINVFGAQAVEFALGDADKQGYGLKVLMSLLWLGVGAAAYVWYENKQQLALYGAVGVALLAVALSSISGSAIVQESVLVTPSLGVQLAKRRRNGTTAVRFVDRSEIRAVVVNEAIVFNDVVYYIALMTEKDDNMVLVFEHFRPRVAILQQVFQHMQTTLFPEDAEKMRLPEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHD8</accession>
    <name>A0A8K1CHD8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002532</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHD8"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="30"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="178"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="391" mass="44187" checksum="E00B2509BFDEC454" modified="2022-08-03" version="1">MTHSEARPLLSLQEPHHESSWFGIPRRIQGMLLVALSVFTFSILSALVKYTTYSMPSMETVFWRSSVACLLNLVAMQVYGISLKVEREFWVPLATRCIGGCCGLVFGFYAMQQMVLADASVLWLTSSVMTFFLGAVFLNERVDAINLGSAFLSFIGVICVCRPTFIFGSSTDAQPPLLGVLSAFMAAAGEATAFTSMRRLKELHFMVTIHYFLVTGTVVSSLWLISKPSTIVIYMSVSLWLAVLGIGVCGFIGQLFLTRGFQLEKAGTASVMRYLDVVFIFIWDTVFLHETIIQNHQQERHTPHGRRQRPTPSKEALHIMADLVYKEIEVMATELQHFAHHANRKVIKPEDVVLLARKDPNLTRMLQRYQREQLPSSTVTKKRRRHGDERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI46</accession>
    <name>A0A8K1CI46_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI46"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46228:SF2">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="535" mass="59171" checksum="F890FAF7056BAA8C" modified="2022-08-03" version="1">MEALEQQLQGLSTEQIRRLLSASGHGDLLETTEKTVEVTEVERSVGKDVVEAKKAEGNEHFRNGEYDAAVRVYTKCIDMDGGKDATYYSNRAMAYLKLEAYEAAIEDCSCALAITPSIKTYMRRANAYIAIQSMDLAVDDLHEALLLEPHNKSCLKALEQVICHSGARPNERRTWLRAVLLSSFRSGWRSLSVKGNPAPPGLNGHALFVCPNDPDQRVHCYGGRAVRDQQAAAYVMDGSDYSWSLTTMAGALPTSRSWHSISVIGDDRLCVYGGVSANGEDPTVHIIQTRRASNGRLIYECHKARTTSPSSPMARSGHSAVTVCSRDNKSPEVYVFGGRTKKGVSAELWRLVLEDDSESVQWSQVALREPTNTPCPRDGHTMVLRQPNDIRGPQLIAFGGNGQLTDDKLGDVWVFDVDTALWSKMQCHGDIPAPRSYHTSHLVDDYMFVVGGRTVETEECSIYVLDIDAQEWFLLPTPEKSSLTPRAWHASVLLAQEKIYVLGGGTFHGPLRDAAVLDLHAFRSCVQQAREKVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIB0</accession>
    <name>A0A8K1CIB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIB0"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="7">
        <location>
            <begin position="79"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="32795" checksum="E601A1593CF377DA" modified="2022-08-03" version="1">MIGADICGFIGNSNLELCARWAALGAFYPFARNHNNNDAIPQELYVWPEVAAVGRKFLGMRYRLLPYFYTLGYQAHLSGLPIARPLFVEFPDDANTHEGIAVERQYMLGGALLVTPVVFQGATSITGYVPAGTWYNLFDYSRLNSTGQDAVWQVKLDDMPVHIRGGSILPLHQSGALTTQAARATPFDILVALASDNKASGQLYLDDGEDIEGVSKSTVVEFRVDSGKLTSKVGLNGYKDAKTKNVSKIVVLGVSSAPKGVTVNQGKPLQDFKYDGEKQVLEIDLKEKFNIAQALTVTWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIB1</accession>
    <name>A0A8K1CIB1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1931567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.230:FF:000003">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000002">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1570.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="2142"/>
            <end position="2273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2378" mass="277141" checksum="31BA2CAA48A7F15F" modified="2022-08-03" version="1">MPPPMGNGKGAVPPPPPIAGVHVANGGDHPMNGNFAPPPAGHEFYQPPSAVDTPMTEEERQKMLEERSRRWAKMNAKRYGEKRKFGFVESVKDDMPPEHVRKIIKDHGDMSSKKFRHDKRVYLGALKYVPHAIFKLLENMPMPWEQVKDVKVLYHITGAITFVNEVPLVIEPVYIAQWGTMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYGDNILDIEPPEAINMELDEEDDEAVIEWFYDSKPLIDSKFVNGPSYRKWKLPVPIMANLHRLAGQLMSDLIDPNYEYLFDKQSFFTAKALNVAIPGGPKFEPLYRDIDDDDDDWNEFNDINKIIIRHQIRTEYKVAFPFLYNSRPRSVHIQPYHRPALCYIKTEDPDLPAFYFDPIINPISHFRVNRASEKKSAEEEEEDEEEEFQLPMGFAPILAEEPLYNENTANGIALYWAPRPFNLRTGRTRRAVDVPLVNRWFQEHCPPGQPVKVRVSYQKLLKCWVLNSLHHRPPKALNKKYLFKALKSTKFFQSTELDWVEAGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPIKTLTTKERKKSRFGNAFHLTREILRLTKLIVDAHVQYRLGNVDAFQLADGLQYTFAHVGQLTGMYRYKYRLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAPGWRVWLFFLRGIIPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGVKANKARTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTNVAHYNRERIKRGATVDKTVCKKNLGRLTRLWLKAEQERQHNYLKDGPYVSAEEAVAVYTTTVHWLENRKFSPIPFPPLSYKHDTKLLILALERLKESYSVNSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVHIEFMDLYSHLIPVYDIEPLEKITDAYLDQYLWYEADKRHLFPSWIKPSDSEPPPLLVYKWCQGINNLHEVWDTSNEECVVMMESRLEKVYEKIDLTVLNRLLRLIVDHNIADYMTAKNNVVLAYKDMMHTNSYGLLRGLQFASFIFQYYGLIIDLLLLGLTRASEIAGPPELPNDYLSFKDTASETRHPIRLYTRYIDKVYILFRFDAEDSRDLIQRYLTEHPDPNNENVVGYNNKKCWPRDARMRLMKHDVNLGRATFWDMKNRLPRSMTTFDWENSFVSVYSKDNPNVLFSMSGFEVRILPKCRAIDEDFTHKDGVWILQNETTKERTAQAYLRVDEPSMRAFENRIRQILMSSGSTTFTKVANKWNSALIGLMTYYREAVVQTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRYSKQTDGGVTHFRSGMSHEEDQLIPNLFRYMQPWESEFIDSQRVWAEYALKRQEANAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKRYQDLRQNPFWWTHQRHDGKLWNLNNYRTDVIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQELDALEIENVQKETIHPRKSYKMNSSCADILLFAAYKWQTSRPTLLHDTKDNYDGTSSTKYWIDVQLRWGDFDSHDIERYSRAKFLDYTTDNMTIYPSPTGVLLSLDLAYNLYSGYGNWFPGCKPLMQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNIYDDWLNTITSYTAFSRLILILRALHVSNDRTKVILRPDAETTTQPHHVWPSLTDEEWLKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSLQRQQVAEVEKQAREQSQLTSVTTKTVNVHGDEMVITTTSQYEQQSFASKTDWRVRAISATNLHLRTNHIYVSSDDIRETGFTYVLPKNVLNKFITVADLRTQICGLIYGVSPPDNPHVKEIRCIVMPPQLGTHQSVSMPIHLPDHEYLEGMEALGWIHTQPNEMPHLPPQDVTFHSKIMSENSAWDGEKSIIITCSFTPGSCSLTAYKLTPGGYEWGRQNKDSGANPAGYAPTHYEKVQMLLSDRFLGFYMVPEEEVWNYNFMGVKHNTGMKYDLKLGNPKEFYHEIHRKTHFMNFSALEAGDEENTNIEEEQQNVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIN9</accession>
    <name>A0A8K1CIN9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="746"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="808"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="845"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1180"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1442" mass="161285" checksum="1E1458E9B15E115C" modified="2022-08-03" version="1">MKTTPTFHAPASPAYSTAGLRAKVPWYRNSLEDSAITAITDAPLPLVVMDPPFVIPKELRPLGHKRRYLRTIQLIDDPLPSAVADFTDSNSLPSNEVPFPQTLRGDTPKGNPQSKFHRAVTFKDTIRPSSRKHSAKAGFPPQLSSFDEQSGGDQLMSKGERHREGFHRSTRSVGRLLPLSDAGYSHRREEIRDERERCRRLSVEEAQDLINSDFYFGPNARTEFFAQYQRIHSKPYLFVEDPAKSLRANNEDDPYNDTPSTESACVPALPSSGYLQRVARELAPVGSAIAHSDLPTCDKLSPRSQYLTACVTRPYLAVPFIMRKAMTKVFDFSFQSLGDEFIIEFSKCLVNDLPYVEEINVRDNRLSDEGLNALLEAVSEGSTMLHLHRLDISQNEMGSKSAQTLRSYVVSQHCSLRTLLVDNADIDDSECAAFMTAFEKNLSIKELSMTRNCIGKSENLNVVQPNFVTGGEAIAAMLHANLVLVHLDISWNYLRLESSITLARSILENHTLRELNVAYNACGDDGAMMFGEALRCNQCLEVLDLSYNSIGCKGALVLAYALRVNRTLRSLQLNGNNLTRDGGQRLMLAICENKGEQGCEVGLRACNLSSMVSQNRGGVPQGSGKTTGAQQAAPANTEVDFSRFPVCGGTSPRVFNSKEPTGRYILQLRDPYDKMIVMELIRLATFKKGCRFVRVEYRGVNSSGGPSSKMMISLVKRERKATIMPTKLMRRPSSSDGGTSDTEDHLDTIGLDALFEDIDRDQSGSIDRKELMHVLNRIGLFPRMENLSDMLDRFDFNNSGEVQAGEEFSAFFFHAVFQLIDSDDSGKIDANEIEEAFQMLGIEQYDDKEILEAIAMYDISGDGEMEEFEFVAFMRDRLLERIKLQLAASAAGSEQDIAPIDLIDGATQKPWVVPDDGQLEIDFLFEREAFATSEEAYRYCKISQQGIEQLIHNITNLAASKGDMEDLFHVAVHDSEIRFTASQAYQLLEACDNLRSVEKKIASIVMILPQMLTAKEAQILVSRTLTLRQRCRLKAEMGSAYSVILGNPTAHYSFDLSKPKDRAAVTKIAEVAQREKLFSKNKSGRGDTSQHGNWENFRNELLDGECFVLTTAFFHMLPTSGKLSFDYVSTTRPKRGTVPLSERRFQQLIKELQTSIKVSTTSETDEPDGQDHELVENTVEEGADTPTELDTSKHKGSLHQTALSRTLSERTRQTEFWDKKRASVLKKGGWQNLVATAQASFRFSSKNTTKETVALKLVQIESAICDRWLSCAQAAEIVACMPTTFHARPETARLLFSRLIDVGNFHQIVDAMPPDDQYVCAKSLGWLNIFNPMVPERAYSLDLSIWDERETIKLLVALAINEPGENWINQTFSNVRGEPGIPGWKLPVRWEKEDEKDGGGVNRSGYLEMEYYSGADRGCAPVPSFRKTLMSRVLAGTRLYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIW2</accession>
    <name>A0A8K1CIW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_002471</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIW2"/>
    <dbReference type="OrthoDB" id="205060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031090">
        <property type="term" value="C:organelle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000051">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="209"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="213"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW63530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="528" mass="58580" checksum="E90F4D790622D27F" modified="2022-08-03" version="1">MAERVASFLATLRTTASDQVEAGLGDELRQLITVCADDATSLGRLIESLEVFLGAMEAEYEPDTKRQWVVRTFDAWMEGTTGALDVPSFQEALQRMKGGTRQSITLARASIDMPLDYVAMPPTPKIGVKKGREFRDHSDNSLMRLTTSIGRGQGRALRQGALLRRAHTVAVGGDEKHMPLLTRASSTLQASIPSFARELTSTILTPLEETFFCQICYENAPVSTAFKLSACGHQFCRSCFAQYLEVKIRDGQVYPTCFHEVDSTDGNDKRAAFNKETKHARQCPYCSFSQACDGPEHPEVSCGGCKRVYCYTHGNAHEQGTCADYEMRQMEADKVNRAAIALISKPCPGCQNSVEKNGGCNHMKCVVCSTNFCWICGDKVENATAPSHYAWWNVTGCAGQQMMEVEDQSRMERVAWTLLRVFFVVVCVPPAFVVTLVLTILSGCCIPCIYWLEMDPKELFVGIVEKLATCLLLCVVWIIVFLFSTVKKSILWIGSRCCRQDKQREPTVSADLDGLELDLEAGTVYDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ37</accession>
    <name>A0A8K1CJ37_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014282</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ37"/>
    <dbReference type="OrthoDB" id="2015991at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="9">
        <location>
            <begin position="521"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="947" mass="106854" checksum="CCD6C17E663ADF98" modified="2022-08-03" version="1">MLPRRQQSATRGRLPHAQSTFTVRRAILLALALVFVLAVYLNFQFLTNARLESSSSSHSSPLKPKTKSDYMHQSKQQNGKKTSAQQKALSEQLAYESRAVQHIVFTSGCADADFVHSEVLAHSARASGFAKRISHLVYGCSVPVIEDWIRRKNPKNDVETMGFPAITSETTMFGEGQLNTTIHPLVVHQWFKQELNRNVLKDDDFVMIVESDAVFTKNVDIWNLFREVDDIQDPRWFGQDAAWYWPKRSPIPQEQIERAVPAKSKALHVTEWREFAATGPYVVEVALLREVLPTVVDIWDKLDVTKRYMAFPLAGAHHAVPIGISGVLSVHNYPSRYENWDFVDDIKHNPCNESAGKDVELESYPITIRPQNFTLPQWIDGNEWNFFNQQIPPQFLQCDAWLMREPSGFLWYLASHTNGYERVPTILRRRHLMSVCMAVHAYNRAAVAYKQQKCEFGYNENKKIPMEFEKPTWGAAVAHDKETVMDVQTPVRYGEYKTKSVAKHLATALPGHLESDGMHFVFVTACDAAAHWQSDVLASSFQHVKQRGALTRIVTGCSPSELREVVERSSIAYPFLHVFATKNYATQTSGDAYAALNRPFGVRDWLRGANPPVNEDLVVLLDADFVFLRSIAVNANYRVTRAKDVDSQNHKEHSEVILGLRQYKRFFVYEGSRSLNTITDTVKQGQAIGQLRATQYKSVGFDAASGPNTQLCPECQRVTGEDALEYYAVGAPYVLTRTDLGTLVDDYVSLSVKRRGLDQQLALAEPIGLSLAASKHNVQFTAFANLAVFGQDSDEYWGFVDLVKQNPCSKSPVPSVIGESPLFLQGSGLYRATDKHGVEWMYSHGLMPDNLFTCDAWLLATPPPSLWTAAKKAEDMKKLRDVYGLCTSIKVMNQAIVAQRERLCPNGFNQNRKLRLVSPRPVADLHVGAVHERWEIAAKEIVREDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJE5</accession>
    <name>A0A8K1CJE5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJE5"/>
    <dbReference type="OrthoDB" id="106065at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="101" mass="11444" checksum="25F444938AFEC2D2" modified="2022-08-03" version="1">MPTPGVVCSPPELKRQLENFSVELNGLVSQLNEDSSRATMTNALTFENGMDETIERACGLLMQVGHLLEELQQEVNTETSLVVHRIQEQRLEATMRSAEWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJL1</accession>
    <name>A0A8K1CJL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_011537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJL1"/>
    <dbReference type="OrthoDB" id="206335at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000031">
        <property type="entry name" value="RNA exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="527"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="719"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="757"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="916" mass="103061" checksum="5FF5041301C631F3" modified="2022-08-03" version="1">MLEDEYEDGEILEEGEEVEDVTRVESVEEDVEMTTAPTEAPVEARGDHAKAVLQTPSIAASSEQARTHEPLLPTPPSRTVRSDASSSDPSGYYEQNASRKRLHSEMQRPLYPSSMPGRNPYPPRRDYRSNDRDRGAPANNSSSNRERHDDREEKYSEDLIVKYPRQVPGSHVLLNFAKWMELAGSRYRRRLDAAEVQEMLVNVLDRRPHVSSYLMSPELFPNKPAPTKVCVVLLGNLHPSVVQRYRNELQFFNGCSSLPCVLTKPDQTRRMETPLPELLYRFPKPSVDIKDMPVNELFYGHELTFLMCHSIGYNDELILQPTGKFARKTQPQGGTWHLDGDLLHLKWRQQHKGAADESANASNPAEEEDDSYILDVLVAEDGTMHKFSTDPETDKTYARDTPEHMNAKRRNTQARSLRLSLIKAVQADVPRAPDGSIIRTTEKTVNGHIAENPESIITNDPSDLKQEDFEYYVLSPEELRQHGYPVDVGIEQTVLQTESKGCSRDQFVQTRPRTLEDSADAKASVPNVYALDCEMCETDLGMELTRITVVDVQGTVVYDQMVKPQSTIINYHTEFSGITAESLQSTRHILADVQRELLSQFLFEDTVLVGHSLTSDLRALRIVHLKIADTAILYPHQRGFPFKTSLKFLTKTFLGKDIQTKIQEGHDSAEDAVAAMELLIQKVKRGPTYGIPETTQLSGAYSTLVDKVAARNQRITILKYSPPDEKATGSDSSSSSEPKPWHLYASGDLHSHLQSPFEHASALARSHQDSTSNSSTHALSSTTRIADAKGLTDSVRAALTEHGDSVCWVEVEQSSGHEVANEFLLRHSQWMEKQSLYCKEIDGLLCQIRDDVLDEQTLLMVIPQGDLSMLRYLKGLRTRSKWKDGPHTDTWTDEMQAAVTDAVRGTMDSCVFLTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKF1</accession>
    <name>A0A8K1CKF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011579</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKF1"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000005">
        <property type="entry name" value="Clan SC, family S28, unassigned serine peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF11">
        <property type="entry name" value="THYMUS-SPECIFIC SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035448165" description="Serine protease" evidence="6">
        <location>
            <begin position="25"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59276" checksum="76B7A453FD49AB55" modified="2022-08-03" version="1">MTPSRALSVLLALCATATCLTTSAFELPTHARNGRLWAMIQTESQAMFTVPTPELWFTQRHDHFASDDSKTFQQRFYESNTYWRSPDGPVILYIGGEGALTKTPGGYVDVLAKKWGAKVLALEHRFYGKSVPNNDLSTPNYKYLKVEQALADLKYFKEQYEETLPAPHTHKWIAVGGSYPGALSAWFRIAYPNTTVASLASSGVVDPVYEFYQFDEQVALSAGEQCANALRETTKAFEDEIKKGNATAVKGLLGAQDLCDADFFYMVADAAAMAVQYGHKDVVCNHMTQALEQKLSLTEEFANFTIEMYGKDFGSGCFYDTTCLINNPSKWADVRSWRWQKCSQLAYFQVAPKTGSIRSSIVDLDYHEKQCQAVFGDVVNPKEGVKEIIKRYGGIHPKGHKIFYSNGGDDPWQRASVLKTISDDQVANLAVCDLCGHCGDLRADPDSPEPLKKQRAEIMEYLTKWLEEEDVIEEAVQDAVKGPLKQVYRSSPFMLLPVLVAVGVLAVIVHKDLIRDSPTNRRAGYVRLEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL15</accession>
    <name>A0A8K1CL15_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL15"/>
    <dbReference type="OrthoDB" id="118200at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="38794" checksum="9700A844812F60A3" modified="2022-08-03" version="1">MEERVLNMQRRELVSYEGHVTTKGSVVDVLRLWKKGSCTYYPAQRLDDSCLTPRSCFDCLNTYIEGEEEGCMIDEAGKCVSKKYYNPELDYQRVEICNSTSVPDGGPVQFTAPNVTYCDLTDPVCAYCRESVFTDPYCIQTVSEKSRFCIGSGGCVCTSVCESKVYEDNVGGAKCIGDALTYKDSKSNMAALQEEAEHKGKGPWVVLSVVLGCLVLVLAIAVVVYRRRSRSSSPTDAASASEPEGVSPPPSGPDRSLNLFGWQAMRQNLIDKEQAELNDPGTMTHVTPYVQFADMVASAPDAEIVPMAFAASAPDHSSHLSLAASAPEANFSLDALLPSAPSFDDESISDTDELDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL58</accession>
    <name>A0A8K1CL58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL58"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="16"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="199" mass="22885" checksum="167B9FAFE528769D" modified="2022-08-03" version="1">MKLTVSYTYATSPVCKQATRTGIWTSEEHRLYLEAMKELRGAPWKEIAAYIGTRTVRQVLSHHQKYLRKVKRHASSESDAVYSREEHAVDLSVLDACPRHRRRRRLSTETEVSGTSESDWEFSSNSSVATDTTLDTLLDQEIFETCDPADTLDIEVLFSFLEKVDTENDWEMNEDELLQASNCSGFPAQTSFMPQKCFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL91</accession>
    <name>A0A8K1CL91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methylenetetrahydrofolate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL91"/>
    <dbReference type="OrthoDB" id="41403at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004487">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000012">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000401">
        <property type="entry name" value="Related to MTD1-methylenetetrahydrofolate dehydrogenase (NAD+)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="1">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="2">
        <location>
            <begin position="152"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35477" checksum="3A910BE95E79457E" modified="2022-08-03" version="1">MTTAGRKIDAGEIAEPFSVAVRKYIAEEMHGHGPKLVGLLANGDPSAKKYAEWTGKACRRDGIRYEVREVEKDDLLEALESANKDPDVHGIIVYYPCFGAFPSFYGGTMDDFLRDSISIKKDVEGLSQFYRANLYRNIRFVDDAQTQKCVLPCTPLAIIKILEHLNVYDKHQPHGEQLTGINITVINRSDIVGRPLAAMLANDGADVYSVDIDSLYLFRRGKLIQTDETPATACKKSRVIITGVPVKDYKLPLEWVSENTVVINVASFKNVDEAALLQIPGVQYVPLVGKVTVAMLQRNLLRLYENFHMKPKKFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD7</accession>
    <name>A0A8K1CLD7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="178" mass="19793" checksum="8BF2882BED75550F" modified="2022-08-03" version="1">MQLNILVVNKSRMLSRGGFDPHGDRRGEIHGHDVRYGRSRGREDETHHEAGNGSLGVHDYRLPTASHGGGCEGGVLEQSRYLSHRGVGGALGPPRPLVDGNPTCGDHGTQCRHCRFHGDEDEDDEGGASQHRPNRYHYRDGEDGGGQPMIHLVDCRRDDEGEILREPKHREEQSPWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLH4</accession>
    <name>A0A8K1CLH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfite exporter TauE/SafE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009053</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLH4"/>
    <dbReference type="OrthoDB" id="434519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255">
        <property type="entry name" value="CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255:SF3">
        <property type="entry name" value="SULFITE EXPORTER TAUE_SAFE FAMILY PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470961" description="Sulfite exporter TauE/SafE" evidence="7">
        <location>
            <begin position="29"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="48578" checksum="491FCDCAD79970DF" modified="2022-08-03" version="1">MTPWSRVTWHVAMALVLTSVSLVLFVHAADVNADTKTADDEAKASIPPLSAMDAYDVIGILFMAFGLIFSSAGGVGGGVIMVPAMVLIMGFDIKRATPISNAAIFGGAVANTSFNLLKRHPHVDRPLIDSDLCLVMIPLVIGGAVIGAVISKLLPSFIITILFVVILLAGSFRTVQKGIRLHKKEVTTKKAEEETGLREPAQSPVTSSSHYVPALTPPIPGTDSQDDTLTQILERERHFSWTKQGVIVLCYLGIVTASILNKVVECGGVAYWVILVVEIPWVVIFSVFTSILLLKDHRRKVAVGYPFVDGDVQWTKKAVIWFPLGCAVAGIFAGLFGVGGAIVTGPMMIEIGVVPEVISATSALMVLYSAAAATAKFAVFDLIAWDWAALLCGLAFVVTSISQVIILGYVRRTGRQSIVILCIGVAVSVGTVLMTYQAIKVTISDAGKPFHADVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLK9</accession>
    <name>A0A8K1CLK9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLK9"/>
    <dbReference type="OrthoDB" id="311468at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013865">
        <property type="entry name" value="FAM32A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08555">
        <property type="entry name" value="FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="216" mass="23912" checksum="7155989C714651C9" modified="2022-08-03" version="1">MPADAYGKTVGGRLQLKGGVALKTKHKKKHKSKKRERDEDDGDVTATRKQEEFKIEKRKGSGRILSSGTTVMGQLGTKFLQELHNGDAIIIKHPTTLVEETRIIRVVLSDVSCSISSAFSSDLVSSTPFQFIRAPPEEEDEQEKEKKKKRKRTADEAAAFGTYAGGTEAGTTFAYRVKKGGAYGGYAIVTERADSDRSREELLDMRAKKKGDRHCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLS6</accession>
    <name>A0A8K1CLS6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLS6"/>
    <dbReference type="OrthoDB" id="114182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="204" mass="23150" checksum="71E5180EDBA1C426" modified="2022-08-03" version="1">MSVVPRSTSPPPATLFELLANVWGVIDYHKIRVSVIRIGSKPIVEYEQEAWRLQLFTAIYRLTPIDWKTSIDRGELFGGPGFIDLVIHNREASARWGIAMVYSRDDLREHVARFRPGGRYAALGLTDFCVLCFQHVTEEELEKDSLAQTDLASDLDVHPMVFVICYDVNVTSVLVWNAKGEKALRVENPAFNRGPVMYRGFSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLU8</accession>
    <name>A0A8K1CLU8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLU8"/>
    <dbReference type="OrthoDB" id="110024at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="17"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="299" mass="33966" checksum="D6248DF92A39137E" modified="2022-08-03" version="1">MGSTAELIWKQFGKKCDLYEVLGVAKGASGKDITKAYRKMALRYHPDKQRGDEDAKVAATAKFQAISAIHSILSDAGSRAVYDETGSIAPSDDLDDSPSFDMWVAYFAKLFPKVTEADITKFEKEYRFSDEERRDVIDAYVKLEGSMQDILDSIMLSTEDDEDRFVEMIQDAIKNDKKVKALPKWREYLKKRAAKPKKKETEAQKKKRQAKTDKEAQEAEELMNAIRNNQNQRASGSGSLALSTKSERNFSSLISSLESKYTDQPKSKKSKRSRADMDEPSEEAFQAAQERLLKKKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMX3</accession>
    <name>A0A8K1CMX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription termination and cleavage factor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMX3"/>
    <dbReference type="OrthoDB" id="77772at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cleavage stimulation factor subunit 2 hinge" evidence="2">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription termination and cleavage factor C-terminal" evidence="1">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14202" checksum="7075FDA370B0D085" modified="2022-08-03" version="1">MATKRVVSVAELSAAELYELVFHLKQCNESAPEEMRRLLQEQPEFARAVAQAQLQLGMIKEQEPATKQRAPNAAGVSNELMQQLDPEQQELLEQVQNLAPEVIQSLPEAERRQIMELREAMGLPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN46</accession>
    <name>A0A8K1CN46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN46"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW65645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="364" mass="41975" checksum="CB767776D8E2BFE9" modified="2022-08-03" version="1">MATTVTSVVTNQRVEFPNVHARPEQQTLGAIVRRNVVLLLLYAVWVLGCTGYFALSAFSVAALAYAAIMGDASYVPSVVRIYIGGMVLYSSYHLTVHRNGQPKWPYLHELCCSTLRKYPYFRHQICIFEEFEEESLKNPDKAFAKPKDKAIYAFHPHGILGCGCTVNGAFSMRFDQADAPWLVAENLFWFPLMRDLFNWMGFDNVRKETFVKYMKEDRNLCFIPGGFEEATIYQHGKHRSYIKRRFGFIKLALEYGYKIHPVYTFGEELAYNTFTPLLKFRLWLNTWKIPGAVFSGRLWCPYLPRNDCEITTVVGKAVQMPKIENPTKEDVVKYQAIYVKALVDLFELNKVKYGADPTAQLEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN96</accession>
    <name>A0A8K1CN96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN96"/>
    <dbReference type="OrthoDB" id="64243at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="71604" checksum="B8B016071541B791" modified="2022-08-03" version="1">MVESGAYSFRTLFGVVKHDDNFGEYHAEYIAHYVGTKSIKESPLFTEVFKNDSTPRQDTVYLQSMDEVSHVSCEGIRTYNDWLYGNEFMRSHWQDIVTQTSYNLTYLQDTELIAPVVDCSFSAITLGDITRARVFYLMRAKTDPSRVFIIVMSISTQDYKIPELYEVGPCVFVKLTVIEDMQATTLPRSLALAMGYPFDGPFYSAYTFQEVTADGFAVLEHVPKDPKVEYRHRVHTASRSGFYCKSEESQSNIKNMNWKVFNDPVLAMTTWQWEGSTVIQNSWGWVRCVYFALAIDSFFNLCVLITVIYHNFQRHKVWVGDAFVSISNTLQLRGAMVLIVWAMENFWQVYVHTLRYGTAQGNLVRFFSFPQVMHGDLMALYVSLAGLLGTLLHERIDPALTIFLFEVGFRNRLMIGELILSLKVIAVRCAITDYLSGIADAPSALKGFSPLRFWTTHRFEQNLSASFAAILPNFMTFAIIIVYAAIRKAYRRVYPSAAISHSSHLTKGSSIISEGVGAKCPFTMFEMATGAELQNRVGLVADYDSCVYIKGMRFATADGIYCNGFVIVDSRWLIRTSDILSVLLIIVTGKRLRDVYVYEVKDHTASQTAKLVYPNTMTLKNLTKLNTTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNG9</accession>
    <name>A0A8K1CNG9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15898">
        <property type="entry name" value="EFh_PI-PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF466">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="684"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="754"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="815"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="884"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1239"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1239"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1290"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1412" mass="158635" checksum="2B1386A4B1943DD2" modified="2022-08-03" version="1">MIGRPQRKRVVFIDGIPIDSTILNAGDSGVVRNEVVDPTALTQLDPRILFDKYDADGSGGIDLEEFKVLLNDLQIKLSEPKTLAYFKRCDKMRRGFISFEEFRLALYTCDPKNPNRTLGFAPGQAMSPKDLFEMFDKDEEGAIDRATFIEVLGFLGHKMPLDKMEGIFAAHEDPELEMMPYYQFKKVWLALVDVRAELRNRHEKFNRFLPNSTLLKKLEVLIHEEEQQEAKTLLEAANSLEEERIAAYRRWLVEEARRLAKLVLAEALDAAGQVYVLGKGTFGRLDGEPLEPDFIEFMDYEGIKELWHDRVRPEVPDEAPEGDSLEEPCRSGDFVPASAKATTVKAKITLTASKKAFQGRQISLVTAFLWGKRIQSVAVGLAIAYALTDAGQVFCWGGNTRKWRYFYDHATQQDPPADDATAPRARPMTTRTEMLKQTMPSQVDEDQRAHETLYVRQKFKKTFVKPERVIPTDEDKHKSLTLVGQYYDLLPANGTAKPLKYQALFDTIEPNLNVDDLVLSLEVRGVYMAKHTRMELLQKLGDCLALEIECLGDKFHKHMKEQDKLARRARHDRQERKRQHIILKTTVLWHEVRLLLDNIVQAEANAFTKTQQEYLAMKRKIMYAKQKMKRQALEGIAEADKRGRLLDLNGITGRGAPQRFHRGDQALQDIAVGSRHVLAIHQTGKLYTWGVGSFGRLGGVRTEHKSEPSPANDDDIDAWHKDIHTPQVVVALEELRFREAGCGFGHSLALSTRGELYVWGSATHGKLGVGPMPSSSNQVEAFTLRPLRLQLSDPSLRIRKIACGPSHSALLTQDGALFVWGGGDGGKLGLGDDRDVGQDLVPRNGTYLKVVDVPTHVTVPCLVQEKLVEVSCGAAHTVVVGQSGRVFAAGSNHALGKFTPVFSPLEMPTGVLIARVSCGNAHTALVSQDGELWTWGNNREGCTGHPTAIPIVKTPTLVSCFYRAPRNLCLDEGVQVMQSTQNASCGPSYALMEQVPASDTFVAQTQQEICPFWQVSLTCLSRIERVRVQLVTTSATARPGSSSVSTRTSTRGSTRSQESIKLVILISEAPFDPTERGKYSLALAKSYSVHTAFNVHVGPSFDWEVPMDTYGQHVRVQLEHVTGMTMLTLRNVRVLGSYADEYRGARVSSVSCTEGATIAICRPLSSQEQLRERFERAIRADRGALWLLEQLETFHPFVLEDRRRREEPWTSSSCVLCRPKEKCIICLLDDTAFASEKEKEAAKKREQQRREEEARRLKQKQQLEAQQKYDRNHPNKRRETKVLATTSFGETHRSNQSKADKDDTGTGEMIVAVMRRLKTLEEKCHKLLTMNMRTEEEETEAQERLAAELFRLDPMAELEQQRQQQQTAASPTHKALKSAILRGLIALFRAKTTIKTDSNATQVVGESPDPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP06</accession>
    <name>A0A8K1CP06_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_012085</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP06"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW66969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="387" mass="42848" checksum="AA78A788AAF98C38" modified="2022-08-03" version="1">MEIPKSLQTALGPLVGICVLSYAAVVLLIPVIAKYLPAKLSGKDLCKRGTPAGDIPIPEALGIVSGLVYVVTLLVTVFLLVDDADIKRMMLWGIVSILSMILLGFCDDLSDLRWRHKLLYPPLASLPLLLNYPGLTAIVLPKPVRFLFSKDTALYSLMNPFLPISDGGEVVELGLVYYVYMGMMAVFCTNAINIYAGVNGLEAGQSFVIAGAVVMQNVVQILRGHDNENCHFLSLLFMLPYLATTLGLLKHNWYPSRVFVGDTFCYYAGMSFAVAGILGHFSKTLLLFFAPQVLNFLYSLPQLFKIVPCPRHRLPKFNAKTGLLEPSTIAPDSTRSNYTVINLFLVVFGPMREKRLVQALLAFQVLACVLAFYVRYELSSYFYDFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP14</accession>
    <name>A0A8K1CP14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008425</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP14"/>
    <dbReference type="OrthoDB" id="273123at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055065">
        <property type="entry name" value="OB_MCM10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM10 OB-fold" evidence="10">
        <location>
            <begin position="80"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="9">
        <location>
            <begin position="211"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="290"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="44676" checksum="02E62558096069A1" modified="2022-08-03" version="1">MNGNGAGGNGAQWNWTALAQQASAKSTSDAAHVKEEIQARLKKVAKAPRSVPMQRQVAPQPSAPPEATSVTTQEKHDVEKFSRLRIAERTMPAADLETEMAGRRFIPLHAMDTTGRAVIADEEVDWVTIGVLVRKTLSKAAANGSSFMVWALSDLEATELAVFLFDAAYDAHWREMEGAVIAVLNATVLPSNEKDRFALKIAKGEEVVKLGKAVDFGICKGTTSGEARCRLPVNTAKSQFCLHHITSNFMAAGKRRQQLNNSFSTFNKSVFSSKSQLKNISAGVYGVRPTATTSNRNGSSAGGWNPVITNKRKRGEPAHASRAMFGAPMVLSASGAVVQKLPPTAAKATGASNNSSSSSRALPAGVSGSLPMPLPQRSSRGQKIIASLLASNSKNGTLPRPTKAKKVDMMKFMSSGLASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPT0</accession>
    <name>A0A8K1CPT0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPT0"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30509:SF9">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN MDTO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30509">
        <property type="entry name" value="P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="579"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="637"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="666"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="877"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="920"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1113" mass="125185" checksum="8E19F0026075DC81" modified="2022-08-03" version="1">MSKIGSPQNDLTVPLNDTRQSVDSGASPRNSRNSRVRKSTAGSDDLNEKISKMKIDMDSNKKGALKQERWSPEFRFNAEMSLRVAFGVIIASFVQTRNPDYDSTAKHDNKWFIFPDWYYLGGLSYCAVAVIFSAGKSVGATIREVCQSFYGVGLALIYNIILFAIIDLHMYEGSYDGYELIEKSFNASPYRINTHNFFVVLPWMMLFTVVVLLLPIENNTKKFALGNNLYFSLTIINPTNPLDSSKLKGVGDDYFSTANVLKNLEMYFLVGFAGTLISLLIMFIPYPVFAINRLRKESLKASDDILDLLNIIVDSYCFKNKNVEHMNFLKLKLHRKFGAAEARYQRMNQLIDDVWWEQLFGFNKILKFNRSMIKNYVRLVGSLIADLRSLNNAMQLEKYAHLHFEYMKALQRHVYLIQMQSGDLLEEISLGVHDCEPLLDLKWLKPLEAQMETTLQMYQRTQSRILRKQNVTLKDIEGNVPLNLFLFSLNSFCSTLIDFQESHNAKIYDTTKRAQSFIATSIKAFFVCHKFTRLHYLGALRASLAIFAGIFLAVYVYAFSNTTPAAVAYVMSNHIGGSFSVTVNRVGGVVAGSVVPSVFQFFISQVCSPKHLNTFLTDLTLFAWVAISMYVRFSGGYGSYAGLVSAFIAAGILLKQSDVCGADGTAALAISSYSTMAQTSVGVLLFIIVELALCPQSAQSLLRLNIQETLNTLQKSFDILFVHHLSSTDELDEKTLKEVRDILQVKVPALLVAQSKLLNEANAEPALWKPAFSYQKYEKILDNCYRLLNNNNLLFKLVRWFNYRVKNDKVDLSKSVDIRNTDDGPSGTGSGAVKEDLLRQKWQAASYKFHTSVGDTFDTLEMLFGDGFLYADPDQTAIFMQMKEAFRLADTDCSGEIDADEVAVLLENIFAQSGAVKEEEIHKYVEEFMAIVDDDNSGKVSFEEFMNALENGLKLEVEVYHRRKPKAPVLQRQPTMSRTSALSRISEESGAEPPLRVSIQTVPSPSKAKASAFTPKALALTPKRPIVQKRMSTVSAGLNSPMMRRQHDVLNVEDFSLGEIAGTMKSAYVEWLMGDRRYEKVTMEELLLLNCLVSGAEGIARNLTTIEEIVVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQN2</accession>
    <name>A0A8K1CQN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011094</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQN2"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17748">
        <property type="entry name" value="BRCT_DNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000099">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000395">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="154"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="762"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="836" mass="91960" checksum="10ECC11E8C77C5D4" modified="2022-08-03" version="1">MDIRSFFQKKDGAATAAKPAGGKKQTTTKAASPSTRKAPARQAAKKVVVLDDSEEDEDMDKDEVEVEVAKPQPRKRIRRAVASEDEDEDDDVLDVTPPKPTTSSSVKPAAPVATTKPAMVKLNVSAEDDDQDEDSAPIQIKQSGKAPPPCAGCLDGKTFVFTGVLHSITRDAAIHLVKQCGGSVATNVSRNTKYLVIGDKLENGNDVTSGVKYRDAMEKNVRVLRQNEFYNLITELAAAKEVGNLRKEKAAAKSAANKPPSTNGKVKLTTTPGSDALWTDKYKPKTLDHMIGNIELGRKLKQWLLDWDAVHVKHTKKIPFTTKLAENRGAKTVLLSGPPGIGKTTIATLVAKECGFECTELNASDTRSKKMLQTGLKDVLGTQAIQFGPAKARLSKRVVIMDEVDGMSGGDRGGTAELIQLIKNSKTPIICICNDRQSTKVRSLANHSFDLRMRRPTKQQISKRLMEIGLLEGLTMEKNAIEEAADRCGNDIRQLITQMQRWRMTTTNITYDDMVNPSSQHNKDESLRLNPFSATQLIFQRESSFEARNEAYFVDYDLMPLMVQENYIRSVMSHYDKSGDNLQAICNAADFIAESDIANTYVRMQQRWDLLTTQAALNVAAAINATGFIGNAEFSRWLGKNSTASKSKRLLSELSVRMRAHASGSREVIRMDYVPFMKEILLTKLLAGEEHINDVIDLLDSCEISREDLTESMESFKLPGIKRHTYSELDTKAKTAFTRLYNKASHKSQGVVERELQATTVKKGRGRAAAAVEEDGLPPPSDAESEAEDGDDVDVSKFQKKPRGRAPAKAKSEDGPAKGKRKAPAKATAASKKRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRQ5</accession>
    <name>A0A8K1CRQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 4E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRQ5"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000043">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="36566" checksum="5F19D4CB3F30DCEC" modified="2022-08-03" version="1">MGEEKRSGWKEAAEGKPNNGETPIQNAYSFSYIKRNSGNKAEVESYEKSIKELGDFKTVQGFWQIYNHLVRPNDLPNTLDYHLFKTGIKPMWEDPANRKGGKWMVRVRKGISSRYWEDLVLAIVGEQFDVGNEICGAVVSIRYTEDVISLWNRNADNSEACYRIRDTMRKVLNLPQFVALEYRRHDTSLGDNSGTTTRNNNNNNNNNNSSVWRDQRSGGDGNNASDSKRASGTSGSQPERSHPRFTRERSDRSDRGDRGDREGRGDRTASSGNSRSSWGRDSKRPIFTKTGSESGEGAPTSTSSNTTRGDSKKASSSSTPNAWQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS23</accession>
    <name>A0A8K1CS23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS23"/>
    <dbReference type="OrthoDB" id="77711at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="624" mass="67668" checksum="BBF0F9F0FE958601" modified="2022-08-03" version="1">MAKKGKRGGGGSGGGHGARAAPSTMGGLVVVNPALLHSMVTASKPQQAKKTDKNSGKKRGPSDPETPTDNKKSKKKRVMPKEDTKQVVSNGSAVGHVQVLTMQREDQLLAGLYWLLLTRENPRSSVVALPNTHQTLSAPQVAGVLKALGFQALAVHNKMANTQRKQSIDRLRSNPHDDKCVLVTTEHFLASSTCVKADLLAVCLDMARVNASASKFARTIALGATTNATSTQTFEPSPSPAALQQLQARLKLATQIVTITQKLGQSHTDDADGKWAAKLAKGADLEDEEDDDMAHKKKKKATKKALTPDEQRLQALSEKLVVLLAKRIDATGSTSTKQQDASAKASDDAQHRTEKLKLLGITTMSAAVGSSVTDERLSAQTQWLDTAPGAQFGGDWKGEIRHGASKDATSLALREHYCSCRKKKPTSSTHLQRWRPNDQPSDHEQWGGAYGKVCGHNEVVMQHLRPFFPQEVLNSRVCSKRHPAPGNQGFDGCLEFLRLACLDGRQALTVWDAEQFLFLTPDGRVLGVKKLPLLQLPLAGLQCLLQALRHWTLACRGQTSPNALLASIRLMCQLGNGDVTSPRLADAKVVKRVLAFAVGGSQRVWKQITRLSPLDTDELYHKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSY0</accession>
    <name>A0A8K1CSY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSY0"/>
    <dbReference type="OrthoDB" id="90288at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="100"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="268" mass="29332" checksum="77E63C1EBE35E866" modified="2022-08-03" version="1">MSTADYKLFTPLTLGKDFVLKNRAVMSPMTRGRADPVTRGPIDSTAVYYEQRAGAGLIVAEASAISEQAYGWIGAPGIYTDVHADGWKKVTDAVHAKGVPRALETDEIPGIVEDYRKSAELAKRAGFDGVEIHGGNGYLVDLFLQSATNKRSDKYGGSIENRTRFLLEIVEALKTVWPSDRIGVRISPNGGIAGMGSEDNYDTFRYVLQQLSQHNLAYLAILDGFGFSYHDKDRLLTVFDAKTHFKGNVIATNSYTRDIAGGALRSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTF1</accession>
    <name>A0A8K1CTF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001687</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTF1"/>
    <dbReference type="OrthoDB" id="190564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30880" checksum="BF8AE0A0FD9F16B9" modified="2022-08-03" version="1">MASIPCISTEIEESDQQIGEYPLQDTLGYGQYAAVYASMLPDRPDEPLAIKAINKDKLVDLVALHRMSSEIAALRDPGLYHHSILALKEVIHTRRFIYLITERGGKDLFEYFGARESGLPEAILKPLVHRVALAIETLHRHQYCHRDLKPENILYAPDHPVEDHVVKLVDFGLCTKGDTLLSEFCGSPGFFAPEILLQEQYDGRQADIWSLGCILLELLVGNDRFATMWMSMYELDTLKDRTRFAELVEKVQRVSHASHEHRTHYQPWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVA2</accession>
    <name>A0A8K1CVA2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVA2"/>
    <dbReference type="OrthoDB" id="74703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="283" mass="31626" checksum="FD15F2EB72D67B1E" modified="2022-08-03" version="1">MSAKTRIIDSDSDSDDNIPLAQLRSNVVVKAEPVVKAEPKVEPVATNAGVKRVKDDDSDSDDNIPISSLAKRIKAEPAATKPTTTPSGTARTQQQKKKKRVKIKFKQQECTEELYGTLKGRLVQELLCRWWYAIEWPSVDTKKSHPHSMQELDGFRGSFIRVKGDEMGSIVDTRNQIGKPSFIHFFALPSAEIQKLLITAYEKQMEVLQEHEGPNAPLLKDLKSALASASKISPDKADRSVTKILKKYKELGDQISEIQEKAMQEDNTGTEEEEDTADDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CWL2</accession>
    <name>A0A8K1CWL2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoyl synthase, mitochondrial</fullName>
            <ecNumber evidence="9">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Lipoate synthase</fullName>
            <shortName evidence="9">LS</shortName>
            <shortName evidence="9">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001734</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CWL2"/>
    <dbReference type="OrthoDB" id="3231at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="138"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="390" mass="42908" checksum="6223FC20A2913A44" modified="2022-08-03" version="1">MQRALGSCSVRVASRGFSSSAAAAAATAAPQVNVTKSEHGERLAALRERLAAEAQQGPAFTDLALTIEDFAFGEEASPGVKPSRKPNASNRKPSWLKAQPTQGPNYERLKQTVRGLGLATVCEEAKCPNIGECWGGGKDGIATATIMLMGDTCTRGCSFCAIKTSKKPAPLDPEEPMKVATAIAQWGLDYIVFTSVDRDDYPDYGAEHFAKTVRILREKLPEIIIECLTPDFQGDKELIDMVAKSGLDVFAHNVETVERLQRRVRDYRANYKQSLFVLEQAKASVPTMVTKTSLMLGVGEQKEDVFQTLKDLRNSGVDVVTFGQYLRPSSKHMPVKEYVTPEAFAEWQKVAEQMGFLYVASGPMVRSSYKAGEFFMKNLLQNRKKEAFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAI4</accession>
    <name>A0A8K1FAI4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013858</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAI4"/>
    <dbReference type="OrthoDB" id="285802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20529">
        <property type="entry name" value="CYCLIN_CCNJ-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="89"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="6">
        <location>
            <begin position="185"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="204"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="36647" checksum="7A642A17CAD0ACB4" modified="2022-08-03" version="1">MEYEYDYAYDYDYAYEGTSLDCDESFGEMSSSQDADEQMPVSLVEDSARIALEDMDLDMTYRCMLRQELNRPDYTRKYEYLKYRRVLVDWMSEVGEEMQIRKTTIHTAIAYLERILTVGKLPAKDRFQLLALSCLMIAAKYHGPEEEVPPISEFWEFGNRCYTYDEIRDMELTTLNNLQWSLTALTPIHFMRFYLSQPVLFSDDEIQGADMVEEALEYYKKYADFFVDLCLQEYQFQAYRPSLVAASILAASRKALGMTPLWREELGELTGYTPDQVEPCFSAVWSHYVRTFGDKNASDKEISPSDVAEYPAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBG2</accession>
    <name>A0A8K1FBG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MoaB/Mog domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBG2"/>
    <dbReference type="OrthoDB" id="448496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050101">
        <property type="entry name" value="CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13939">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE AMIDOHYDROLASE PNCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13939:SF0">
        <property type="entry name" value="NMN AMIDOHYDROLASE-LIKE PROTEIN YFAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="1">
        <location>
            <begin position="11"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="264" mass="28912" checksum="1C981679A04E85AE" modified="2022-08-03" version="1">MSTSTAAPGAALCVIGNEVLTGKTQDTNSHYVAQFMFRRGIDLTRIVVIPDELDTIASTVKELSDLVGPTGYVITTGGIGPTHDDITYEGVAKAFGRGVELHQPTLDGLRESMLARGRPESDLNDERKRMAMLPVGCKILSTASWVPIAVTENVYVLPGIPRMVREMLEYNEAHFTGVPIHRAYVHTLRWEGDLARQLADIQTRHPDVAIGSYLNLTHDKTGEKDESYNTRLTIDGRNADQVDAVADEIARAVDGQRFHATSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC44</accession>
    <name>A0A8K1FC44_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_013389</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC44"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="13">
        <location>
            <begin position="94"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW57915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="349" mass="39936" checksum="65535D279E839DAC" modified="2022-08-03" version="1">MSWKSYSSSPEGSASPRSALSLHGVTDYQLAMDLDKEEGFVLEEKSEDGMEMATNVAEWTDSEDENNFDDSSEDAVVAAWLRRNTRSRRPVYSRKTGTITYDQDSILDIKSTEVMKKMVSRGAVDQVYGCVRSFKNSHIYLALGTDEETYRQGLYAAKVFTDPSNGMVSSHKEFRCLIRAAKCIRAPAPLAIKEHIVVMSFIGDADGKPAPTLKEAKLTLTQLQFAYVDLVQALRKLFQQARLVHGDLSEYNVLYQHQKCWLIDFGQAVDRTHPEVLTYLRRDLRNLFQFFRRQGLPDATPDSPFGILSKETAYAFITRTECPDDVLHMYPKLPFDRKQLERVRFRRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCR6</accession>
    <name>A0A8K1FCR6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCR6"/>
    <dbReference type="OrthoDB" id="158677at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF1">
        <property type="entry name" value="ESTER CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="36721" checksum="E3B1DE9B3F3F61E8" modified="2022-08-03" version="1">MEALGRTGSEVSMTAFDGFRATTEWKEWDFDCLNNLELDLGLDSFLMANDFIEPLGATTSAPVMNMAAVPAQDVTSAMSTPVSPPVFDDLMETSCSSESEMSSIADDELLAMASLPKRSRKRKIPQTYPTARALADAKPVVTPKAANDKKIKMTAAQQKAMKKREVAPLSAEAERLYRRRYDILHEILEAWNTGGIEDMEEIADDVYDEDVTLISPDYSEGLKGAKALMHHWGLLLDSFPDGIMEEYNIERDDPEGQKMNVSWIFSGTQIFPFFGVEPRHEKVTIRGQSFFTFKGEKISQMVLSWNYREAMMKLMGLKAPSEDTPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCZ7</accession>
    <name>A0A8K1FCZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014384</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCZ7"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="59452" checksum="6B968C6DF4E14388" modified="2022-08-03" version="1">MTEDHASMMEAALLRRPSALVSSELSVAYHHDVTLMSLESMESVAMMSKPEPDVRNGYTRLRGASVQALGPEGDMTHDKDDTLPHEKSEFKKLCALSAPIVFTYILEFLPGVISIMLVGRMDSPLTKEYVGGATLSSMFIYLSGEAPGFGLATALDTLCSQAYGAGKPQRIGISFQTGVIVLSVVFIPIFFLNWYSEQFMIWMHQPEEVTELAGIFSRWLLPGLPFLFLYELLKKVMQAQNVVAPMVWIAILSNVVNLALGIWLTWYTSLGYEGAAIARTISNVVLPAAAIPYFMWKPEAFHVWWPGFQPKQALAHVKVFLTLGVPGMFMLVLEWLSYEIMAVFVGWLPNSVVAISVHSVLSNVANIAFHVFIGISVAATVMVGNYVGSGQHDHAKMASQLGMKLSLAVAVLIVVLIAALHRQLPQMFIGDDESVSESAKAILSLIPFELLDSLNCVMQGVFRGTGRQKFAAILNLLAYFVVGLPFGFLLAFQLDCGVQGFWLGLTGGYLLSVCISLVKICRTDWIAMSEEAEARLERDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD61</accession>
    <name>A0A8K1FD61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-structural maintenance of chromosomes element 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the SMC5-SMC6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NSE4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD61"/>
    <dbReference type="OrthoDB" id="361242at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027786">
        <property type="entry name" value="Nse4/EID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014854">
        <property type="entry name" value="Nse4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08743">
        <property type="entry name" value="Nse4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosome element 4 C-terminal" evidence="9">
        <location>
            <begin position="213"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="298" mass="33980" checksum="289B95C8D9C1A187" modified="2022-08-03" version="1">MAPSSRDDGGSTRGRKRGFLENSKLTDQDRRQVRWKERELYQEMKENATELAKLNSNRFQATTQELDEMYENVCYPREANLDASNLDELNMAVAKQSQALGASDLTKYDVSDLIRSGREACVSESNGRFDWETIGSAAGACFQSVPEISFLFGLMNTQVVHKERKRARRAKEDENVQASQPSEYTSKKDRKDAQARRLEVLQNSMEENRKRGLFEIVVNAQSFTQTVENMFDMSFLVRNGAVEIGVDDRGLPYLENHEGRAEENIPAQTQTIISITPEQWQDIAEAWQVEEPLVGHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEV6</accession>
    <name>A0A8K1FEV6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEV6"/>
    <dbReference type="OrthoDB" id="166945at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454266" evidence="3">
        <location>
            <begin position="17"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="688"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="74344" checksum="FD261E677CB5092A" modified="2022-08-03" version="1">MRVLFAAAVAASVASARPVSVCRDATYEIADVRGALCSGAGKTPAGTACPLKGDAASADCHPYLSSFNGNSCVAKENAVCQIVTGDTWGCVFPSVGCKPTPAPTVIVEPTCADWSYSGDDVDIGAIFDEGTAPGSSGFDGMVVVEESWFVQEHPVSDLYCCDQKPTTAPSPTTPAPTTPAPTTPAPTTTPPPTTTSPPMTTPPPPPPTTTQPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPPPSSSPPPPTPTPTTPCPPTPTPTTPCPPTPTPTTPCPPTSRPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPSPTTARPPIDQKPTPTPTSTKPTTKPTPTPTSAKPTPQPTTTTPAPTGQKPVPTPPVPTGQKPVPSPTTTSPPYGQIPVPTPAPTAQVPAPIAQVPAPTAQVPVPPNTTPAPETTSPAYQQGSVPTPSAGETTTLASTLSSNSNVGSGASAGSIIGVTALVVVAIGSAFFARSAYRRRRDSADMDRVLTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEZ4</accession>
    <name>A0A8K1FEZ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.130</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Coenzyme Q biosynthesis protein 4 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:81179"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="4.1.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of a multi-subunit COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the COQ4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.130" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEZ4"/>
    <dbReference type="OrthoDB" id="4249at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120539">
        <property type="term" value="F:4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03111">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027540">
        <property type="entry name" value="Coq4_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="31035" checksum="78EF88677CCDDA77" modified="2022-08-03" version="1">MLGGAQAAVRMARGAGRIVAAARARRVASLQAAAGGLHAGAELPPVAGEPCKRVLYDTHMPTSPTQKILLSFVSAFTVFANPERGDMLATLGEVTGREALQRVHARMCSDPVGTRILVEQPTIRSDQIDFDYLRNLPKDTFGYAYSQFMDAHGFEADGRAYVKYIDDPELAYVMQRYRELHDFWHTLFGLPPTVFGEIILKYVELVQTGLPHCALSGFVGPLRLESAERKRLVTEYIPWANEAGHQAKFLMNVYYEKEFETPLEELRTRLNILPPPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFV7</accession>
    <name>A0A8K1FFV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFV7"/>
    <dbReference type="OrthoDB" id="59491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="165"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="447"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="98345" checksum="0C99DC8C49DDCA98" modified="2022-08-03" version="1">MSEYGANFPTSDDDESEETFQEQNEKLESFGQLIWYFALVEKTREFKSRPLEEWPLVELSNPEVGWRYSDEAFDDQGESMEENGDVVQRANGFHKVEELLKTVRAARLDKSRFLEWCPDADPRSEIVDALWFHVDRVMEELQAMRNCITNTLDTFIRDADLTSTSAGEGVVLPGPVDETWMSSLLIPSDLKTVFVSQVAVLENVPEEKKDWHPESNNQVLDLVHPSLYCCVFGTTKRVPASEIDSNVDLTVVERMERTAFKATEVTCRTSSSDNYQWIPSDFAVDESGHVKILSYINNLHPVTHAAMYDSIAAIFKRFVSLFDQVLTDLVAEYYKQPCPFRVPDMSETRVDCTNYLPERLPIPDRIPLKSGCPWSYSLKGTTVQVIVTIAEIHLTPEKPKYLGGSWHIEGTGSEEIVATGIYYFGSENITDSKLSFRVIVVEPLHVTDDTTWISASLIALELKTAFVNQVAVLEDVPEREKDWHPGSDNQVLDLVHPSLFCCVYGETKRFAETETLDSTDEMSALRRMETIAFKATSAVDTPEYSGDQYEMDDENQWIPSDFAVDDDGHVKILSYINNLHPGDHAAMYESIAGIFERFVPMFDRVLSGLTGECHEPHAIEIPALKKHAEYLPEISVPGVFPLEPDYETAYTLKGTTVQVIVKIAEIHLTPEKPSYSGGSWHIEGTEAEQIVATGLYYFGCENITESKLSFRAIVSEPDLEDTSRFYLAALYGLERHELLTQSLGAATAIEDRCFVFLNTLQHKLEPFELIDATKPGVRKILAFFVVNPSNRIPSSSVIPPQQKDWLQRALPPMLEAKNLPVAALGGKLTQLLGDGMTLDEAKAHREKLMTARRTYNAFEKQQELRFSLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHQ4</accession>
    <name>A0A8K1FHQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHQ4"/>
    <dbReference type="OrthoDB" id="68267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="24965" checksum="26B8A11C3D5BDCC7" modified="2022-08-03" version="1">MTATPATNTNTILITGSSRGIGLALAKQYHAAGWNVIAAARNPANSKELQQLNVYKTVQLDVSDEASILRAAKELEGEAIDVLVNNAAIGAPNTLQATTKTEFVDAFEVNVVGPFLVSRAFVPHLKAAVAVKGFATIAQITSMLGSITLSTGDLLFPAYRTTKAALNMLNNVIAHELKSDNINAVVICPGSVATDLNGHTGILQPADSAARIVKNIARANAETTGHYFSHEGGEYPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FID3</accession>
    <name>A0A8K1FID3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FID3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="868" mass="97400" checksum="F91C64A9FACA3883" modified="2022-08-03" version="1">MKATLYEQPRQAIADCHIDMVYDYILLVTKAFGEIVTGKEVKRLHFNAPIVACVCAQFNGRLEVLMDEIVTGARVRANIFFDTFMKLGNKHLGITEAKRGDIRQGLERAYIGCEVIADAEGLSKVYSIVTDYRVKKKKTPEDEEREKKLPLDFTNYNAVLALPEVYFVDDEDLFDDEPASAAPSVRPLSAAEQKRLVDEAFAQDLNAEVASLLMELEELSVGVYSAFHDVKLEKATLIEATAVAKVAINSAASVIAKVQLCYPTIRDANALMGLIRDRLTLVELDRLEARVTAAWHHDDSEDEDNTKYRYVPGTVLMDVLWLAPILIAFGNQIRARPGMRFQANTDLHGERYSEDDSPLYSMPVVRAGATFISQQLPPVYVRGFSTSGHVSIQLLFVCICWLRSVAALEGSRGLGRAISLSITHQWDLADRLRSSIEHAGARYIDPPSLENWRNLLADIKNFDGCTGQLRLNPLLAGCFLKYHQAKYLSIGHNTVITNSRFEAFCHLYSDLRDRQLLEEIPFIEDTIRVYESAIFPAPRSQVTQGSFEQSFLTSKKQVEASINASSIRRSSRIPDPTTPAWLRMQFEHFSHAGNILFANEYSALPTSSTAYASWTSLLKAVSNQFSKEIFDSRVLSRDLLKLNDELTDLFFTLRDELCRGDAYEDMLEGPFHNEIQAVTSAVEACVMFPLLSLLDSLALDGRVRVMPDIISDLEDFQRRRMRGRSSVSEVVVGYCKHAADVIARKFGGGSDKIEKLYFTLPPTPAWASLEFGDAHSQLTSSHLSKRMANPKTFLQTHRSQAQVMDYLLDLMKNSRGPLHGEGLRDFKQNVIANPGISIWHHAIRLSSCRHCCTAQQLDLLTTGGWWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIE8</accession>
    <name>A0A8K1FIE8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49627at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2361" mass="266479" checksum="4657722E87A1EBFD" modified="2022-08-03" version="1">MDLDLVGDSGSEADEYGELDGMTLAKTMFTPDTQEFARENEEKPTTEARENAQQSQLVLETLPLEASRVDPENDAELIVEDGANPNTPGGVDEESEDEMEEAAPQGPRFKIGDIVHVAARTWPGINKLGGAGKIATILEEVDESGEPTFLYNVKYMLGGFEKRIEEEFIEDLVSTLEQGARPHKGRVFYHEEFAHEPNKKKRTANMDNEPKTTGQADTSVTVQKPKLVKTPTPRREHGPLGEDPLTNEEDDPAIEIPSSDDSDFVVGDESDAESSRVTQKLDDYSFIMASTPQDSVVREKESRDRVPRASAEKMKKRKRRRRSDESGKAEKTQSQKRSRRIVVSDSESGGDASRLERQQSKKRRYVGGYVHGTEDPEGRFIQPEGDLAGLPEDILRELNIKLGKSKGELRNQLNTVADRLLENLRVFELKKKEALISLNRVLSLNDDEAHQVNRTLVELGDFVRRQLIRSGEDVINEIIKLLEKKGGSLPERIDLQFEHWKQQISDHDIWVKKSLRSLESVFAHRGMSTTFSRELLDNQLAGQDDYEDANASHEEDLAPQDVSKSDSDDFIEVWPQNIPRKPEPRRRRTQDAEERRYRGVQSRKRSLPTKTQSTLDDYEFHDYERIPSAGLQPTSRMSNFRLTRERPQTLSKDPKWDWARKMKHSNQQTYSTAHRVAQVFRGVKAGRTATTKDTSGSVQIARLKLRDKRYRNPSFPSQPRLHNNGVYIMEQEIMRQDAGPRGMNNWKRGERSMVQDLSLSTHAQMNDMEPSSDDNAGWERIFKLLTEDMSLPLKVEVDVSNEIGPVFYNDTIIFDEWCDEHDFKRIVDSAAIVRQGLTTLRLKEFSVMAALNSTKYGQKGEKLEDSLDWKLLNTEAEEYHSMLRSFSANTTLVFQDLEGAEHESIMKDLFVEIARSLKQLPDCNTVFGSLPAYPYFFNVASPEATTTPLLTAINRSYWYYIQILVVIKDRYATLSRGGSMSSLAVLDILPPNRVALASCLFLVDLNIYLPVSHRRNRPLPEASNSNVALSAPSTPALSLWLLLQRLLSDGALQVGTNSIGSTNLWTFLQTTYQQRFVEELVIGYLDHKSNGGYVRERAPVGLDKGRNKCAVLQSQLFAADQMWDICVAIGSVHQTSSQEGHDSQWGMVKELMHPTNPDLLPFADNVSSSLSHDKVDLGKSVFKLRVLRRLLYLSAILPPSSDIAELALRQLWDSGASQTSLSEIIAFLEKLREVDSTSDDKILLSLFSEEAEDLDATGLLARIILIQVSKLDKAIYRNRFRQPVLREISARFEIHKLQNAQSANTSSTKPAVKDPVRAKTTWQWGNQAATAVQNVEVPVEKACQSTVPLIKNRIAEAGMMVSILVALAASSLCLEQDAASVSSRRRTLKREVEFYCKELWNIGSDVIEIGSYLGDALCFIGASAIDANVGYSTVFQQLNNLLKRSSDKYGSADKVEGDEIISPEKKAVCQDALATMLSSLKALRDLSLRLIDRIQQQKGGPMEAEDVRTSITMIINSGLSSCLESAADNLVPVSVLDVALELLMMWIPQQRYEPNQCLAFRKPTAASSGEFDEFGEFDDDVWATVDLDNISNQAPTAKLFGTEVVPFAREVALQQLRISLQRLVINFPTKRDRSYQEMFAIDLLGYMISTCSFQFSWSTVSLSSLRTRTLAPRLFAAILKYNPEKQWFSTCYLSEQNADQDLTAMWLMSTLDLKALSPLKATYQLGGTSSICTSRYSTYWSVMTDALMASLLKDDQVVRYKMDAGLHRLLWQTASQCTFPDHIRANSDPDNARVLYDMHIGVFRSFCASTRLIWEELNVDPVSNRLGMNRFRLKMMDSQRGIFAALPEAYEINLRSVCSQLDGGKVNWYRLSAEFLDVFAPLQSARTLHDLEDDSTHGLDKSRVDPAIQPLVTLFRFMYDCVDSFLFHSSAMAIGQQNIFFSVMKLMFRQAYCAEFPLAEKRLARQPTMNDTGAQNDWLQLNQQLMLKTIQDKSISSVLSTVSPACRGFIESVRLFFAFQKYPSLMNWFAQTLETYQTVKAGWFGSPLRILLYNVLDPHGPLGVHSYYPMEADSSSTQFDPSRIRREAFYLACGLFPCRCTASYEHTRSSHLQHNGGMNLKILRCFILQSFLTQLMESSIAHDEDVQETLIPVMQFMKAVLHHCNINDSANMRDNSESGFVASVEILPCFVHVAEQVILMMRNNDSLSSSISCVIFIEFVRITEELVRVNVVRPDDLVGKMLHIALRCAGCMYASLCKYSTAQLEPLFAEDVAIPFLDELAALKKRVMEIERVKAERIIPSSPTKNAEDYGVSPLRTRLDLLSAIRRLVKHCHQVLPPQDSQLSTLLHTREPAQQVEASMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIU7</accession>
    <name>A0A8K1FIU7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIU7"/>
    <dbReference type="OrthoDB" id="123202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="493" mass="55365" checksum="19DA9D3AA0FD372B" modified="2022-08-03" version="1">MLCRLLLLLDSALLDLFSTMGLAVILLTSYYHDYDPAFGGFAMDFWYNDEWVMNSFNEFNFVLVVSWMDMLSRIVFYVGTIVAVENLKELLRPAPLTKLTIGPSASLMSGKEPVDLVLKSTASLEPRQRRFDRAAHLVLVVWGVVVLSLHMHADTRENVAQCLMQVRPWGANKPTCVLLAMDCNLNDLLGHEDDITPFWELVDLASVNRIVIRHCPELHMPPSLQRFIRLDTLELYNTTVLDWPDSAALTKQHHPVIGSFFAVRTNFTGGLLPPGLSSPNFPQSIYDIEFSVTNLRALPDDLDTRWPSVATLYLELCQFDHFPSALTRIQPLYLSLSANQLTESPVEALQMPNLNFLTLAANPISTLETRPYRNVEDIGALRRLKLMETNVSSLPRWMDPLLSRGTVAKPSVNLHNSPLCTYIKEVENGERSHFPAVDTTPHDQLATVMMLGDMPALAKGVPCTYYFVLLYRLAGEDAWSGLTPQPVSFPATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIZ2</accession>
    <name>A0A8K1FIZ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIZ2"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="4">
        <location>
            <begin position="41"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="5">
        <location>
            <begin position="144"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="332"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="66274" checksum="2811B20A7A4F555A" modified="2022-08-03" version="1">MENSGMARSNGLETSTFSRLPKKPLLSCVVDGVAMQKLPSPKKKALDPLRYIPSERTSFFCVFTVLARFEEHDGEVRVQRTYPQFLKLHAKIHKMFPRSTLPKHVPSVSKKRHDDEYLQEKRTEMNEYLKQLMDVPEIRLCRILREFVEDTQVSDDSDDDDELPSKALEGLPGTIVTVRAGQSFSVSLNMQHTGDVASWQFKTKKHNIGFSASFNALSVRVYSREESSVKPVKGSFKCTEPGTLTLNWDNTYTWSKAKVLVYWAELESTQPKPSTNTQGKAKSGDTSSLMDGRRAGYIAQSRNPVLYPRQIVNSSLSLITKPFISSGKSNQAGFKSGLLIVERQIKFRGRRWYRKWFTLDMHKGILRYYDSEAAARKGLSLAKLNLSRKNACLAITSSNEAAPTPYLFMVRARKRCWKMCASTRSEYHEWEHAISTAILAAQVKRRRDQADPVDPNELATRTNPEEPHEDDSEDSDDDEGKDDEESEEVDSDHSPCVEVPPNLVSIFPDSESPSRPEEWKESNKHITLVIKKALMLLGLNGFVYSLRSSDLFVLIPMLVAMNGLLLVYYYEQSTSTTPTKDKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ21</accession>
    <name>A0A8K1FJ21_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ21"/>
    <dbReference type="OrthoDB" id="79704at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HORMA" evidence="3">
        <location>
            <begin position="452"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="781" mass="87180" checksum="50C452913EB65177" modified="2022-08-03" version="1">MQIESRGPAIRSVMRFLRWLFGPQGFFGIKGPHFRALFLSQQLVLVVFRAYQASQLSASVPHVLTVWSYSALVVAHCWSFLVIRRLCNHSPGLVRLCFVLSDACLGIITTIIFPAILATKYVKAYDSKLTNFPIHLNQDAVFSATMVVELHRILVASWTDLFVRIVMSISILISLGDAKVLIEKVDARSASDTSPHLEDIAESAVVPESKRPITLVLKLVIFAVGATILAFQLKAQQKSHNHSCVLPVHPWGTGRPGCALIRLNCTLEGIQGSKDEVTTILTAYSPDSVQVLELLSCPALRIPSYIQSFGHLMRIYMKKSHLVEWDVDAALTRAYHPRLSTLQIQDSQLPNGLIPPGLMDPDFPPNLRIISLLALNLVDLPLAVAAAWPPGTVLRLESMNLTQIPPVLFRMALYYLSLENTALTEIPVELFYTPVLMYLNLKAAQIEVDTEKGAKTPTMELVRVVTSQFCRLRRLFPPECFTLRSVEADEEEMFHVLKKPPLVDNEAERLYDLLEYGVAECIDRCCLRRMVLRVHDGKSHEVGEELELAIEVDGNKPSQSKNSVEIREISRKQRLLLQTLAPLPPRASFTVRLELIPERLPYPSWIPAFFTKAPSESTTQTQRPGNHQRQLIALSVSRFRTDDCHGNMVLRSAYDALEELHTQSSAASLVQFDPVFTVADRNERRHASPLHEKRRNAKLTQHKKQKVARIGSPRAPVVASLLQGHAPMSVAMTPIISVARPSVSNVLKEEAHDKQKLSSVSTVVASTPIHQGPTVFKTECG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKL9</accession>
    <name>A0A8K1FKL9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012376</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKL9"/>
    <dbReference type="OrthoDB" id="168261at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140996">
        <property type="entry name" value="Hermes dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="7">
        <location>
            <begin position="595"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="688" mass="77341" checksum="5374C0D07A7034A7" modified="2022-08-03" version="1">MEDLHMKRYSDAAGLTSPAIAAESKVLTSHDSDSTETTTSEEVVEASTGTQARERDRGLEVYAHIKLIDSRFRCTLCSSSEHGGWASRNTPKFWLHIRTKHLKEYRELRGTEGPMESTTEGATGSSTPTGATSTMEALVATSAPTEWIINGSHSLDIVEQRGFRDFCNALQPQYQVPNRQAVPDRVMKRWVDHKLQVRQTLLRQLQGTHRASLTVEQMSSTKPECMAVTLHYIDDQWNTRSVVLAYVRLVYPHSGARLARRLISAVTNMDKVLLGSLWTVTADNASISLDMVNELNLSLRRSPLKGESTRSQVCCPDLDAALGELREAVRTLQENPGLLEKYVEECKSWRWDGKKDCEGFKLDVVACWSTTYGMVEHLLHCTIRLDELSRRISGQCKGYSHLAGDLADSIKIKPESWTLAEVYRSFLEPFKDAVTLLSGTTYPTMGLVGAVYRSIRLYVDRLVESQEKEVQRLNETSSKAAPTVSAVLGFRETVALMFFKGVQSKLCEYEDIALTREAKIAGGLDPRCRGYQPTETRQLIIDEFMKCYNKRFEDNYRALTVSTRPSKLQKFSQLMADSVGVSTAHRARECIEEEVDDWLALTPMKLDSDARSVYSWFKENGDEFPRLKLMARDFLAIPATSISSEAAFSKARCTISNRRARLGAGSLEMISELQSFMAFNRGDQSVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKP1</accession>
    <name>A0A8K1FKP1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_005650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKP1"/>
    <dbReference type="OrthoDB" id="166847at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="438"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="55461" checksum="7754751A9137C9F5" modified="2022-08-03" version="1">MDDNQAYEEVAVDEAAAYEGAEYDGYAYYDPNASSDAYAYDYSAEADGNYAEYDPEVYYYDPIAQSPEDPGGYQLTQDDTWYGRQYDETAYVYEGETEAYEAPTSPFGDEAYWEQHGETTEMVMEAQPGEGLAEIEAPTPIAMSPEAEDPSMPTTESSVHTPSTPSKRKKKGKTKQERIQQRQEQLEKEEEERAKTAEDSAAKTDTADPTTAPLSPGKKTTTRAARPPTFLEREKAKLNLQLRKARSIGRKRIPVQLRVLTETRRHLSPMETYFGGSVEAVLSDIFWASIKGDLRRVKFLAEVEHVDVKDHSLDPWNMQQTPLHWAAKGGDKAVVEYLLHAGVNPRSLDENGSLPLHLACWGGHVDVTLALLRVTDTKDLYVRDYDAALAPLDWANIRGHTHVIKAIEKYEDSLWLPKFVDDLIRGIIRYKIKMYKDAPKGAKSPTQGFRFRPKAAENNAPGQAGDATEGKPDSTQVTADSANKAQATDNSAAAPVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH3</accession>
    <name>A0A8K1FLH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH3"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032870">
        <property type="entry name" value="ALKBH7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052">
        <property type="entry name" value="SPERMATOGENESIS ASSOCIATED 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24626" checksum="891CE021A61225D8" modified="2022-08-03" version="1">MRSLSSAVSPYSWKHSALVDPSKCVDDAVGVNDLLVMPEVLTEQEEQIVSDECIKLLRRRRYEEDHWDSVIIKFKEMERSRWSAETARILDKVRQAPIIPQDLVYFPPVHVIDLAEDGYIKPHVDSIKFSGQVVAGVNLLSPSIMRFKEEEGESIVDAFLPRRSMYMMTGRIRYHYTHEILPGMQLFRGTEPVNRTRRISIMIRDVHPDHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM24</accession>
    <name>A0A8K1FM24_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitogen-activated protein kinase organizer 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002194</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat MORG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM24"/>
    <dbReference type="OrthoDB" id="71437at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051980">
        <property type="entry name" value="WD_repeat_MORG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842:SF3">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING PROTEIN 83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="274"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34187" checksum="D11B70F05B5F8A62" modified="2022-08-03" version="1">MPAPVPSQCVRVLRGHHGPVNAVRFNEKGTYVMTCGQDKTIRLWNPHRDGLEQQGDGLLIKTYQGRHGYDVQDVAIAADNSKFASCGRDKAVFMWDVPTGKVIRKFEGHDQSVNCVRYNADGSVLLSGSYDKTVRCWDIRARNSYLPIQTLDEFKDSVTSLVVSDHEIVAGCVDGVVRTFDLRAGKVFRDQIDEPVVSIALSTDRQQLLASSLDGSLRLIDRGSGTEMKSYRGHRIDSYKIECAFTFDGGYVVSGSEDGQICSWDLVNGRMQTFHAHGKPVRALACHPEEAMLVTGCVVGSVKVWVTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM59</accession>
    <name>A0A8K1FM59_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_001156</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM59"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000063">
        <property type="entry name" value="Multidrug resistance protein ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="850"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="933"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="93"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="414"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="708"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="653"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="666"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW69000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1275" mass="139683" checksum="A01DFFCE538DAC6A" modified="2022-08-03" version="1">MTSGKYATFATDAPLSPSPRHPLSQAGLFSRVFLGWASPLLRLGNSKQLNADDVWSLQPAHQAGTIAKSFSSNLEASPSILRAFLRSFGGRVVLTGLAFLTATGATLVGPLVLNHVVNTLSTETYDVSDLSKWIGGLLLTLVVQALADNYANFDTEVIAIQFTGALKNLIYHKTLKLSAASRLQYSTGDITSLYTTDCQFLLDAAFYIHQFWLMPLQVICVSVLLYQLLGVASFAGFAIIGLSFGFNHICSSRMFTHYFAFVKAKDVRMQAVTETFKAISVIKFNAWEEKAETRIDEARKTELKDIWGFLVYNGLSVVITWGLPVFISVFSFLVYVGVMKQSLTPAIVFTSIALFQLIQSPMRLLPHIASGLLKAVVAQKRINAFLAAAERDPENVHTVDHPTATSYIKRDIVVAVENGAFTWDANASPVIRDATLHVRVGDLVVVHGAVGTGKSSFCSALLGDVTKISGSVFVGGSVAYCSQQAWIQHMTVRDNILFGRPYDHEKYQRVLEACALTTDLASLPAGDRTEIGERGVNLSGGQKARVALARACYSDASVFILDSPLSAVDAIVQNEIFNKCILGLLRNRTVILVTHSPEIISSEYATRVVTINENGELVETRNGTSSRTENKPLVTPLPKLAIGRQDNYVTSNTEAWPSVTQSPRATNDKQDANETDKLVQDEGRAEGRVGRHVFATYYRAIGGFPVLAVVVISQILWQALQISSDFWLGDWSTDATSSTAPVSQSYRMTVYTILGLAAAAMVVMRTLVISWCGLNASQRLFERMTHALLHAPMKFFDATPVGRILLRYSSDTSDVDLMVPLGIGAFLANIFSVSCTVVITGVIIRWNGLLLLPIIVLYVLVGVFYLGPAREIERVLKTTQAPVLSHLSESIEGSAVIRAFGSDRVTRFRGINDDKLDTANKVRFAKLCVSRWFALRMQLLGSALVFIVAASLVLLREHLSAAIVGLAFSYVLKISQSVQAVVTTWSIVETTMVSPERLQQYVDVEQEAAYKIPSMDPPCSSEWPTKGAITVDKLSFRYKTSDRVVLKDLSFAINGGEKIGIVGRTGAGKSSLTMALFRINELAGGSITIDGVDSSKIGLKTLRENMSIIPQLPVLFKGPLRKYLDPFNEYADEALWNALRRIGLSDRISGEAEKLEVMVEDNGENFSVGERQMLCMTRALLKESRIVIFDEATASIDHETDQKLQRVIREAFASSTVLTIAHRLDTILDADRILVLDAGEIVAFDSPSVLVKQGSGHFYELMREGGYLAKVVQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FME4</accession>
    <name>A0A8K1FME4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FME4"/>
    <dbReference type="OrthoDB" id="71006at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053290">
        <property type="entry name" value="TSET_complex_member"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45521:SF2">
        <property type="entry name" value="TRANSDUCIN_WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45521">
        <property type="entry name" value="TSET COMPLEX MEMBER TSTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1106" mass="119423" checksum="120792446BEC1C55" modified="2022-08-03" version="1">MATTLGNGGSTSTTAPSAVVNIPNGSIYDLQKSLSGVVLLAYLTAEPVSEKKPSRLTEATFHPVRPWLAAMDAKGAGFVWNYETKEVVTEFSLESSQDAAVASMEATEEDEFATSGAVGTTTAKGILQRSSSPTAYVRGSRSKVSAPRMLFYDHEAINWTTKTSNDRTCYEDWLIILTTTHVMFCDLNQPTVIRSIPSDDLLRQVPCSIEILPSGVLAIGCLDGKIRLWSPAQRRTIETIDSGSLKEVQQLLLLPLCANEGNPSVVSAHFLACATVDGHMSTWKVSARGECVRVPGAVELKEAYRSFDASSGLSELKFHAHQLVVIAASKDGTVYVLDVFPLLRQNRTMMLTAILPTTKLPGATVFAGPRKGAYVVVSAAASGAAVTISELLNKGRGVGRDNLPASYHELVVGASFDSKDLRQPVGLAILKKVKVLSLSGSLQNPSLLCCVTTFGILVMKMTCLPSAPSIWIRRGAEKSPLLLFPGPTRVGIRINGEETSTKQEDYKLQSGMDAPNEKLKTPMLEACPSNAAFVSALLPASTHVEILQMDSELRNQKSINMHMVFSGNAIAVAWHANKPRFALLVPQEPNARRLTRAASNMSTPRRRGFMFGGSTKGFGAEEAAAAAEARLRNSMARAMTLVMYEIADDGHVQVVEEGCSCGDDRLLHVFSGPLLGVVKFESEDDGGSSGSTGGSSTSIPGTDGLHDSPSARNKRTESSVFGAITPTAAAGGATTGSFSAADNDGGDIKKTTLDFYEWEASSNGGMKRIGTGIDCPLLLEWEKVTHRFCALVYPRCVRIYRVTASPTVEVALLHEIPTASTVVSLHWMYQTLFLSTPEGITCYFICKTRFFTVDLASVSAYTSGTSGPLLYPKQQHLATEATTLLGIHNHRLVLAAPVQSLHSLDLSNKVLQCAMLISIGQADLALQVAEHFGSELSDWISSLFEAFAFVTHAVRLSKLSLRLKVNIGIKHQLLDELATWLSTETFPVSPDLTGTSLFQRACTALRRGGRKEVLESLFQQQLAKPDHNQEAVFIASLLQNQELLAQAHQGKKEWGKAHFAAKRQSSSVSNDLLGHWNKALQSTTAPWKATLEQQTIRPPEVLTLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPB5</accession>
    <name>A0A8K1FPB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tectonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPB5"/>
    <dbReference type="OrthoDB" id="166585at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006624">
        <property type="entry name" value="Beta-propeller_rpt_TECPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051513">
        <property type="entry name" value="Tectonin_beta-prop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23250">
        <property type="entry name" value="DYSFERLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23250:SF3">
        <property type="entry name" value="FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19193">
        <property type="entry name" value="Tectonin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00706">
        <property type="entry name" value="TECPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="39407" checksum="E88CFCAC3D46C119" modified="2022-08-03" version="1">MQMNSNLVQILFDGRSVCGVAPANTICNDDVFVGRSIGDPQWRQLPGKLKQISSDGKQICGVNAANDIWCAGDGIFSNPNWRMLPGKLKQVSLADGVLYGIGPDDMIWYGMSDGEDSFQRVSGTLRQIAYDGEMLCGTNAADEIWCSDNGLQGSPNWRRLPGKLRQLDVQGGRSIGVSGDTNIYHKWLTQPPGVFAGWRQLQGKLRQLSFDGKTFAYEIFTGNAVGAVNRVKLPGNLKMISTDGKQICGVSKDDDIYCADTGITSNPNWRQIPGKLKHVVVLNGVLFGTNSADDIFTGRSKGDPKWLQLEGKLKMVDYDGVRGKPNWYRTGTKLSYVTSVANRVFGANSTQDIYTRVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPF0</accession>
    <name>A0A8K1FPF0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_005777</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPF0"/>
    <dbReference type="OrthoDB" id="109171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02892">
        <property type="entry name" value="zf-BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00614">
        <property type="entry name" value="ZnF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="11">
        <location>
            <begin position="58"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="626"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW68309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="804" mass="87344" checksum="C5027BAD2071F52D" modified="2022-08-03" version="1">MGKRAPLDAADDLTPGAATPSSTPVHAVNGVSAPSSGASTPSGVSPTVVSTSSLNAPPSVSAVWAYFEKDAAGNSICKFCDRVIKGHHSSNLLSHLRTAGRTDAVHQQASAICEEHRENKRNIKRQKMAIPTAAEFAANYPHLVAAAAAAAVPAFGAPFSFKKDNPLFPSSASALAAAAAAASLTRDQRDAIGVITPQPHAFTPDQLTQDFTLMVLVDNLPLNYASQPGFQNLSTLFMGDKKAELPDEEAVLKTIGMLHQSLTLTTKMLLSRAKAVGISLETWKHPSPGLTTFAQYLVVNAHFSINFRDYHVAISCTPVGNGIDTESLRAILEQTFERVGIKDKIIACVVGDLPWKEGAAITITNTDLPCGFTPINIDGRLATPETQRTTVIASAASLLRQTLKKDVFMASFPHVVISIDAFLRRLTARTETTATLKRKYPHLDPDSTAAEVMFVSYYDYLRVLQDALADLEQLAQDYQIEFLPNSTVEWVNYVIKKLRPFVRYADAFEGEKQKKSGSDREVHKDGLSSVSTIAAALLTYVDKLTTSVDDSTSSSEVDPQLWKSFFDSVAKEIRAQFGSNPPLSVAATLLDPRYKAREYCYVVPEVDRSEAEALLRRLFLWSGDDAVSSRQNSGDLDKTPSKAIGSSDDEDEDEDLLAHLPSTTPKEAVSDDNELTVTWAKELSAFLSLPLAERNVDPLSWWKASQLRFPLLASYAEVLMALPAAGSTGETMMKSISQVLLRTDGASQDPLVATNPVLVEAFLLFQKNREYVVEWFRSTATVVADPSIVSEVEAASSFKHIENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQI5</accession>
    <name>A0A8K1FQI5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014604</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQI5"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="18951" checksum="9F1D18ECB3390E09" modified="2022-08-03" version="1">MADRPTKRAKTAAAPSDTEGQAAKPEHLQVCSDAVEEADDAAVDVLFRLTSLKDAPERHNRYAIGLQELFEGEFTQCLLTNYMYDLPWLFASCPRLQDVPVVLVHGERDRHAMTQEWNGYGNVMPVAPYLYGNRHTKMAVVLYPTKARVAIFTTNFTAIDWYNKTQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQT1</accession>
    <name>A0A8K1FQT1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012014</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQT1"/>
    <dbReference type="OrthoDB" id="296793at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="9">
        <location>
            <begin position="190"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="10">
        <location>
            <begin position="276"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="790" mass="88233" checksum="E6D109309535C662" modified="2022-08-03" version="1">MTTMSALPSVKDAVLSVSQETLLHALERRVQLHVQAERTAALLPDATEETTSLPVFLKQHVHRLSTVSTASTTAFARQVDACVDDWNALYAHAHQSFALVEEMESSHGQVVSKTQALYDSFETILQQVEALNMRVELIAAPMPHFLAIDGIAQTLGFGVQFAAPSSATGDAHRVQQPVQVFQHKRSIDPTTKAFQQALEKIDVAVMFLEAHKEFKDAACYIEAYRTLTAGAIQCLKDYAVSGLDAARDVVLEAIAKTSQDNTLPNPGQNLDETSPYYVHFQLVVPALNAVTQQLERLARSKAEAANASTYMTNVMALADVLNAYASQRVQLLTPVLSMYFESLSHGTDIVNLLRLSGTYMVRLCEAEFRLFLNMFGREPRDAMFIFKSGTQTDEEDDEEDEEATAFERLIFQLSGVLYSIVRPQMLVQKDLEVLCEIIQVLQSELIEFLITPRAHVVGFVEPVMHRMIQDAQERLILCVQKYIRDEIEGFSPSPSDLDYPNKLIAAANDESTANSLYATWYPTLEHTLLCLSKIYHFVNMEIFEELAQDAIQICTASLKMASADITALKGPMHGSLFLVKHLLTLREQITPFDIKFSVRAKALDFTSSADAMAHLLSDVSAVFSLSLQDNALVGLFTQGIPQIQETTSDVKKDLELELRKSCTGFIDAVLDRLAQPLLLLMKQISDVQHRASATAPADLRKHAFTRPENVSKTLDFVSKQLNDVLPEILETIRLYLRNASTETILFKPIQRNLLDAVENLQTLLQQSYSAEERQSYHAAFQLLLQQLRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRE2</accession>
    <name>A0A8K1FRE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRE2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17288" checksum="7EE2608C1F8147C8" modified="2022-08-03" version="1">MEDDLWRNDGSFRGLQGNGGGKRGGGGGNKGGGPQFTRVIPKFLQKYEQAPGVQTKFQPPPQPEGDDGDDDELDDVQKAALEEYACKQKEKAEKVAAAAGAEDDDAEKEKKTKSKQRVVELGKTTDGEGKKKKRKRKDDEKVLSNKKLLSFSMDDEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS60</accession>
    <name>A0A8K1FS60_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS60"/>
    <dbReference type="OrthoDB" id="159517at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="71277" checksum="27D37D111D676B28" modified="2022-08-03" version="1">MDVQRAAVMRSFSAGVAKASSASAARSPHMYQVKVEHELYSSVLGADDHALSVTHPSPATSTVTASPSVGAPSPYGFMPHATADAMEDTVQPAEDDNLFAAYSAESHPQDLDDPDEWDYYYVPAPLPTPVTPSSVNSSAAMPPRSAPFSSALAAINNASATAVGRATARGSTSTRSAGVRQGVKRPLATTTGTGPLPSPTVTVASSMIAMRNHPDALDLGSAPKAPTKSTPARSTARATASRRVKKDDSSSSSGEAEQPPTKKTKVSRERQLKINAASRRCRKKQKLELQFLRTHVVELQSALKDQLLVMRGSNSQQQRFARLASFLEDSIHKVDEMSSGGRPTTPKATVFTESELQQLKAVATVEPPAAIEPAPTVVSQPEAPSGYEISEERKKTLLNIASFMRNNISLESQSFSPEVISCLPIEMDGWQLRLAITEKNYTIHNCKFFPCNVRDMYDFCWETNVASKVSIKQGKEDFCVVTPLDTDVAHVYSKTIGKWSLSVHGVPNVTYNSLVCRVYNPEQKRAIICQQSVLEDRDFEDESTIPWLFKRWVVFQPRVVDGVEGTFVEAYRTASYATGRLIYKEDNTYDSFCEHLIRRYAESNALLERMMARDSRFQHFAGLDLAASNDAALDPEETTSDRMVKDLLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2P9</accession>
    <name>A0A8K1C2P9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2P9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="330" mass="37078" checksum="859A24D32D7C6CD4" modified="2022-08-03" version="1">MADASESSTESEYYDEDVKAEQVKVEKTEVKDTSTGHSPESNSLVESAFPLSAPTQFVSPFAALAQTPPLASASGKSVSTEYTALSRSKQLKLQTADLVAEHKTLKLTVIAHCKNSLLVEKAFNKLVKIPVLPSGRSWDDIGKNPAHRAMIKRMRNMKRAEQRYNTKNSNAAKRKPLPPAKTLALTQELVDLDRLTIQTLTEQIINWVYHLQQEDVQLSKEAEALVAKYKRDKGSETALEELVEELERECETVGVRANPEMPDEAITGLTCERQHRRRYQVTAMKYVKMYRSVLDRAGVKVPSEIAQLCEDETLQARIQRYETASDRVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2V6</accession>
    <name>A0A8K1C2V6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2V6"/>
    <dbReference type="OrthoDB" id="439710at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00777">
        <property type="entry name" value="AspRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04317">
        <property type="entry name" value="EcAspRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047089">
        <property type="entry name" value="Asp-tRNA-ligase_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047090">
        <property type="entry name" value="AspRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001750">
        <property type="entry name" value="PRK00476.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="GAD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="173"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="654" mass="72901" checksum="4B4049E5D733B2EC" modified="2022-08-03" version="1">MRLLTPLLRPRWQQASRALSSATATSSSAFRSHTCGELRDGEHTGQRVVLSGWVDAIRPFGPISFISLRDRYGITQLVVEKAALDAQTAAVFNELRPESVLQATGVVRARPDSMRNAKMATGDVEVLVDSLQELNSSASLPLQVATGSELASEETRLRHRYLDLRRAHLQQNLVVRSQVSLATRNFLCQEGFLEIETPTLFKSTPEGAREFLVPTRNRGQFYALTQSPQQYKQLLMVGGLDKYFQLARCYRDEGGRADRQPEFTQIDVEMSFIKQEDIMGLIERLVKTIWKAAGMELSTTAFPRMRFQEAMHRYGVDKPDTRYGLELQDVGDLLASTEFGHFQTALSGKRGTVRAINAKALALNGFSRKELDELEKTARRLSKIGLFVVKVEDDVTQWKSSFAKKLSASEIERLNERLNVERGDVLLFAAGHYDDVTNLLGRMRSHCAQLLYAKGYLRDELSPTNFNHLWVVDFPMFERSEDASDDGDVVLSATHHPFTAPTDESAVVLQELLQRADGEGSLLQDPETVDQLLALRAQHYDIVCNGWELGGGSIRIHNAALQQAVFEDVLDLPPLQRQSFEHLLQALSHGAPPHGGIALGLDRLVAILCGAPSLRDVIAFPKSSTGNELMTSAPGPVLTEQLEEYHIQLLPKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3B9</accession>
    <name>A0A8K1C3B9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_010480</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3B9"/>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF160">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="293"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="747"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW55598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="797" mass="86891" checksum="7AB9D99CBDEF253C" modified="2022-08-03" version="1">MQSAFGLAKNVNTRPGARRAASAYHLSGRLPPSHSASSLVLLGESEDRTEFPLMPPFSSVSPVASLSSSSSSSSWGSRSAGDLKALGDGNRLAVPTAGQLVVELIDQQQHVGEEHDRNVTQRGSAVDKTNPFIGYFQMANEDKANSATVAVAASASTLRDSLVGSYQYSSTALVNQQKRFTEWIGAQSTRLPSFFTRRENEQSGRKKSASSTKQNYGKEYADGAQLQVMPDASRVPINILIGAERHDDDSVNAGANTRAPVQEKGQHNPVLARQSSISSSSWAPSSSRFEQDFEVIGILGQGGQGVVYKVQSKLDGCYYAVKKVTFPKAIQRNSPALLQALREVKAMAAMAPHENVVRYHTAWLEEELVDQHEVRASRGSSRRELSMEEATVSNKENSVSFFSEDEYSVDTLINFEGSIGGFEFAESSQSIIAEAEAELLKARPCLAAVQEVESEDSGSVSSRSSQPETNLVLYIQMELCGSPAAASTTEAYVSDCEQQEDDSFQRLIKRLTSKSERTMKSAVTTELADMVHSNFTAWLRSSVEARANPDENLIVHREGLKLFLGVVQGVQHLHATGVIHRDLKPDNIFVHGDIAKIGDFGLSKSIFGDNSPDNMRTKYEGFEDDHTTALGTFTYASPEQLGNNWSHTKGVTSNAVKSARYSIKSDIFALGVILLELCYPCSTMMERSQVLTGVRHGVVPQLALQRFPEEMNLVLRMTAVDPAERPSTDEIIEKVRSLVAVKDTTSVRSAVEELLDLQAKLALAVNQLRDRSQAAQQLESLVAELQDKVQNVGLALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3H4</accession>
    <name>A0A8K1C3H4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3H4"/>
    <dbReference type="OrthoDB" id="4564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050970">
        <property type="entry name" value="Cl_channel_volt-gated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45720">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45720:SF10">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="93772" checksum="1A86197A94B87BFA" modified="2022-08-03" version="1">MQSPGNLQDELLPSHMRRAGRMESLHEFQRRAMSYDEGENKQSPIDHQIALDIGRNYRLDQLLDPEGKKSPQDQHMSLNAIFGDQLIDPDSGKKSPQDQHMPLNAIFGRAKSQSLAVSELSEDLRHAVRTRRASSSLFGGVKRSKRTTEKYYRRQAKVLCFLVLLGVIGGPFNYCIRLLFGQIKSLRIYLVGLCSSDGSQFVVWTAHTVFFTMLGVLWTRLSPVAAGSGVSQMKSIMTGIDPRMYLPGYFDASTFIAKVFGLSCAVGAGLIVGTEGAYVHIMSIITHHLLHTPMFAGFCGHLNGRLQLLAAACAVGVASTFSSPIGGVLFSMEVTSTYYLISNYMKAFISSVSGSLMLQITLALADSSSKELESTAIKTSLGPVPFVMWEIPLYVILGCLIGVLAWGMVVLLRVVAQKRKKLRTSKSKWKRRFATWVDPLAVAILTATVTYWPGEFARLKSLEELAILFTQEQLPESWQIVSKFYSLAILSITYIILLPLSISLQIPTGIWLPTFIAGAAFGRMFGEALRSIHGLEEITPGAFALAGAAAFAGASTRTVSAAVITLEITGSMPLMLPIFCTVLAAIGVFNMCPEQSVYDTLLLISGMPYLPLVDFDPKLVASDIVEPLLVYVTKRTTVGRLLLTVMRMKDQDLPVVHNEVDMRLLGLVDVNQVKDLIRHYYEANNLPDVEVDLGEAPTSTPNDFSWTTLMSKVSRTKNAPGGFYGQMSYDYMYQALATTIKDRQPNQIGPNGAVPFMMDDDRMMQLISESWSEDKKRLLEKPIKLTYGGHCALKPMALTVSSFTPLDDLHMIFTMMRCDHCYVCDQGSLAGVVTTKTMLQISALEQHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3M2</accession>
    <name>A0A8K1C3M2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol-3,4-bisphosphate 4-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="159395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016316">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039034">
        <property type="entry name" value="INPP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187">
        <property type="entry name" value="AGAP000124-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187:SF11">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035482263" description="Inositol-3,4-bisphosphate 4-phosphatase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="709"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="740"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="777"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="858"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="908"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1165"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1228"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1165"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1845" mass="201586" checksum="579439A7097A3673" modified="2022-08-03" version="1">MAPQTSWFMTLLLMAMALVAARASLMDPDGSYDAGFVSTQPFPWPPTPSPTTKTPASTRPSTPSTPLFPPMTPTPTTSTPAPTPAETGAMPPSPTQTSPVQWTDQPTPEPTTAPEPVDGAGSSSAAEPPAGSDASEPPAPAPEDGASHEGENSSAGDPTDLPTDTPTAPGNETDLVGGEANLNVTAPVLPCGDANSTTCSTGVTPVPGNATAAGNTSAPVLAGKAVTSVPPATSKAPAVTPKAAPPPYRSSYCRCKDNECQNDIPGDYGAVCEAAKADGSCRSGYKKCVSTSSYKIQMYPKTPKSVTDMSFSLLASDIIGTLYNLGDQNPISSNKKWWVALRLPTDWRFVTWDMTTLQVQLVAGDSNEITTRQFQVRPCKEVTDEKNCRDENVGFVDISDMLSDWETLMTSTSKSPITFQLLKSIVSGGQSSSAVAEVGVFLVFEKATTARRLDMRELYVAATGSADAADINLGDLSVITLATMEVPSISTGRLYSSLLWVEIDKKKATLSFSTSTIIGNNSLDPKVCINLRSSTCAHRGQTPTSNVTFESGSIAAYVAGGNPFIDMYSLPGDSPLKVTPVNETYFCVESLKPTGLNPNQSWEVNREFAFQLYVQGAMWSSTLEQNKTGNNFRVPFLAEISLIDRDVVQGSDCSQLIVHDQTYTNHELSVYSVMSVTIYAVGLVGAILITRMNGISFSAATFYNDMTSVGVIMTFTLSIIGNAFWINVSSDTLATNASHVYYLLRILAICFSWTMMTSVCFHWSTVLSNDVRKIKRFYLMLAYSIVNGGFFAFGLFTLICLSDFFKCTYDDYLKNPKYDKRICETDYCPDLQPFQWKYATEDLCRGVPYAEWYVPTSFGAEILMFVAAVALLVLGTSVLRRGSRLIEHSGDMIDEASIAAMRKSLTTYLVVILAITVSLGIPVIVNIVLYTLDWKLNAILWYTFTIWLPTIIPPAGFLILQWNPRVNGGSWSRGNQDVKNRKTIAEDKYGARENSTFGLLSDGWAGITDFPDTDYLPIGAETKEGNQNVMALSVQLVTPVSLGHACYMELYIAETEGNDVTGDDFEGHVRSRRASISALIQSGIQRESMIHRRSGLATFAHPMSASNPSWVRVGLTETVVPTLIHSQGDTSKQMATFMSILQIPEMNSNPMVRFVVYEIPDSVANSPASQKSPEIDGYTSNPVEGRPNARVSGLGLSPPSKPRVFCEFTCSSAELSSKEDIRLVAPQGSHRASLPFNPASSHGSPLGPPDSKSAPVLRVRSTTVTTRTLKENNGFYITKCFQFSEGDEMVVEDMTESIFTNEIPRQYLDLLLKERGQDLSRAERDLREFEEKCKLGLGAGMYDNLIDQIQGENVQAVAQAWLEERIRQRSMYMDALKECQQLCVDRAEEGLNFKASTEKKSSQLRFLPINLHVQDMWVGPTSDLRSQFSRRTSEAVKLYSTVTVGAFAAHSFKFRHGAGILTLRSRLAKKPSNDRLLTRNNSGVSDTGDADLDWTQAEVRAEDELKWQLATRTDMCVSQALTGLVASFCRNLEAALQHPNDRHFLKVINSIGFLWQIESLLSTQGKEIGMLEDYYAAVQAMGGVRFMLDTSPPKHLPSTLNLHMKDADLPSVVSARVSGDARHGNLTVVIGVRCSSDVLKVIPQNIREGGKISVTPVFFTQGINEMQTLANSSSAKKTTLQDNINRDSYEVLCEYVEKYKKLASEDPSAVPTDVTTIANLVADLEERIMLASKQMVKTKHPKIIQQSSRLCRLLGAGRVTSCKSAKDRTGMSVTLEQGHLLADYHGLPAEFLTRTISTMRSNGVRLENAFKNTGKRQFAFNSLQRSLLPDEYKCPEGTYGRGNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Y1</accession>
    <name>A0A8K1C3Y1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Y1"/>
    <dbReference type="OrthoDB" id="129756at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="52698" checksum="11F83211DB6124DA" modified="2022-08-03" version="1">MAVMEEVEDATGRSVALELLERARRLCLAANELALPQLQGQARDGDSKAAKPRKPELPSSSNAPRLPILPKKKRVLSAQSNKDREQSRDALPQINVTEEWRKQREAERVRQAQERAQARVLRISNQFDPCNIPEVINLPTNITNMHSIEDEQTKQEKIRQGQARAHERVRRTRQRYSKPDQREVCDSDTKPVTPEHPEKVGAFKRQTLERLRRARQKELDIKKVQVEPVESRPEVEFDDPDERKRLEKERRRETAQRLKRIQALADEQKRKEQEQFEQGLSAFKSKRQELDRVAKGLSNHRRSNLAPVGLAQSIEEGTSIESQFPNVQEASSPSSPARGDTDKAHLSVKRENAALPWSGLTIKTDPQPTAAVSSGFHDEPAPSRHSKLPPWKRPPVPILPTTCYSYKAIISSTPNILSSPTQTSPQGSYAQRFDSRYTVSAASGTTKNQSRANGSTSKQQRAIGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4D2</accession>
    <name>A0A8K1C4D2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008948</name>
        <name evidence="4" type="ORF">Poli38472_008949</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4D2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272183" evidence="2">
        <location>
            <begin position="20"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="360" mass="34708" checksum="679835F75CD58599" modified="2022-08-03" version="1">MKSAAFFLATLLFAHGTLALDKRSHGHFQPHRQLTRAADADSDTKSTEEQDEMHKKAHIVVKKIAVPVPIPVGVPQPFAVAVPISQPALVANSATSVNSVNSVNTASSVNAASSVNSANAGAGAGAGAGAAGGPTPAPTGGAGRPTPAPTSTRPTPRPTPAVTRVPPQQPEQPEQPEQPEQPEQPEQPQTQPQFGGTSDLQQPATGFTGAANNGGAFQPGATANGANSGIGQGLAQGQNGFGGIGGLGGQGGLAQGGQAGGQFGGAGMGMGGGGGAPFNNGQMNGQFGGGQFGGGQFGGGQIGGFGGNQGMGGGFGGGNNAFGGGGGNNGFGGGLGGQSGFGNGAGGFGGGANRRARRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4H3</accession>
    <name>A0A8K1C4H3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_008924</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4H3"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="65"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="246"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="407" mass="46608" checksum="A276F857067D85E3" modified="2022-08-03" version="1">MSEVEDRRPTEQEQEGAIPIADGDIETNWDEVIESFDGMDLREDLLRGIYAYGFEKPSAIQQRAVKPILLGHDVIAQAQSGTGKTATFTVSILQKIDTSLKETQALILAPTRELAQQIVKVIVAIGDYMSVQVHACVGGTAVRDDIRTLQQGVHVVVGTPGRVGDMINRRALRTDEVKLFVLDEADEMLSRGFKDQIYEVFRFLPEKVQVALFSATMPLDVLEVTHRFMREPIRILVKRDELTLEGIKQFFIAIDREEWKFDTLCDLYETLTITQAIIYCNTRRKVDWLTEKMQSKDFTVSAMHGDMEQRERDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRSGRFGRKGVAINFLTHNDVRYLRDIEQFYNTQIEEMPMNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C515</accession>
    <name>A0A8K1C515_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006579</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C515"/>
    <dbReference type="OrthoDB" id="199717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="218" mass="25157" checksum="3C2FC5577A4A5A2C" modified="2022-08-03" version="1">MADTDDNIAAMTPAQRKLFELRMKVNAGRKANKQEVAAEHERLNNGDKKAKKEQQYKKREEQKAIKASGKAHLEETADVAQYKAKKDDQKAKRKAAFGWDAFNQDSLFKAYKKRLTHLPTEAQAKSETGTEQAITTLEDELSYGKSDNVEQEGLNRMAKELEDRIKARKTFSRRRQHRDGEDVDYINDQNRMFNRKAGQAYDKYTVEIRQNLERGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5C2</accession>
    <name>A0A8K1C5C2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5C2"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18470" checksum="490171C64F1ED28A" modified="2022-08-03" version="1">MAMRSGLLRAIRGVQATPRGSALRTAMQQRRDINYGHDMHKEMLNGTAKISVTEYDDGGFVVNDVNLRGGVVLFPEIAMLWKPKRFEEITKESLELFTFANPPVEILVLGCGARLSRQLDPELAEFLKVNGIVVEYSDSANACSTFNILNAEDRKVAAAILPCEAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5I3</accession>
    <name>A0A8K1C5I3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5I3"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="121"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="30113" checksum="0452378643E912B0" modified="2022-08-03" version="1">MRWLPTNVRIRIDGGVEFLSYINNQHPVKYQATYESIALGFRAMVPLFERVTTGLRGPKPISYIPSLFDLSKPTGNLPLPAIVSLRGSVVQAVFALHEWSWDPMADEPVGTSEWDGTDDAVLTVGHMVVQTENVSTARLAFCQNLQSTVTSFGGRPEPQWEDAGSIACLDNRCIVHPGYYQHQIKLAERVDATTPSSIRLLTISLLDPKKPVVSTSEVPPQRLDWIQEAILQPISRSRGLPVDLERRIMEMLGVGMSVDEARRHRAAMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5L4</accession>
    <name>A0A8K1C5L4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5L4"/>
    <dbReference type="OrthoDB" id="104052at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="214" mass="23635" checksum="E7E6EC3C5C7C085D" modified="2022-08-03" version="1">MRSANGHTYGLNSQAGCLFERSRNVMRQNSFARGRTSMKRKARDDGSSGDEAYCYDGRGNRVLMDGLKRMRVTSPPTSVPSSPSSCSSEDEYSATEDMMMDTNEARAEAKAVVVASKRNPAQDARPVMEYKMPMYGNEYAELPVDMSGTALVVFNPNWALAVERSPKVELVEDSVVVPASPSHDDATSSDDEHFVRFEEIHDDDDAQADAMEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Y4</accession>
    <name>A0A8K1C5Y4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Y4"/>
    <dbReference type="OrthoDB" id="68469at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="12"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="380" mass="41900" checksum="E4CE16FF7BC408C3" modified="2022-08-03" version="1">MASAMEYGVYGRVLFCGQLEKRRDGAVRGGWATRLFMLTPEALHYFRRVTDQELLGEERGSVPLATIKVVRAMPEDDAPISAVEMGSEHYYLEIITDTRAILMRVPVAEASTCESWSIAIEEQRKVLRGERVDQNASSRIVPEALPSPTLLATNHEMYSQFEMTPPRVAMISVISVADHESKPQEMVIKRKVGWGEVVDLGVVSQGGACVILLQDGGLGRIGTQALMGSWDAGQACWIEVSNVEHLTEVEVTVSCKVVPAPSTPLSPKRENSTEVLPKWVEWVDEGSSIGFLLMCLFVHLLYGVDGFHWSHKCCLTLGAALAITTILNGSSKNAPMSPTPVKSSTPKQLPKLQFSLTVHRCRIKMEGTEYMYPHDQKTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C665</accession>
    <name>A0A8K1C665_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C665"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="161"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="332"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="963" mass="107358" checksum="D4ECCBC32BDE2424" modified="2022-08-03" version="1">MEPVHPKDVTVLWHGWLKKLGGFSKRWRRRYFVFLATANGMKELRHYDMHKDVATLLLSTPKGVIAMTDVTGICTFTPSLTSTAAAASSASPPLGSTRKNLIFSRQEGHDGTSAQDQRFAILTPVHVHMLAFQGGQDWGSTDSQRGLALLASLSAFYPAVDVLHTGYMSKKRERTVHASAKGIMSYWKRHFFVFLSTGDLLYFRDDSLQEFQGRVDVRHAPTVRVTGERLLEEKKKELGVLKFAKLPATYERESCLVWIATPPSKMFVVKLQEDREGLSSDGRHQELTPAAKKWLSLLLQGHAETKYTQLEQCISIGKYDPTPEIVSAVRAGIPDELRGQLWKGFSRSVDMQRRAELKQVVRNTAKTTTIRGMASKDATTAGDTSAGSPSGFYMELSEPLDPNAAHTPEYQMIFSRLCAIAVREVRAGIVEDDPNLEGKDDPTLDSSSARESFLYLHLGDDGDSGGNSDTEASPTSAAANTSRPQSIKQLGRGKYGHYVYPSDAPAHEWEISARRRLLIAASRFNPFSHPCPWKVACLLLAYLDEESTFWVINSILDIYLPGYFHGYRPALQIDVSGFDSILRDRVPALHAHLKQLNYPIEKTVERWFLSLFTSTLIPLPTVLRIWDAFFVQGVRIFFGVGIALFLRAEEQLFQAKSSKEALEVLHMIERTSIDADALFSHAFKDDLNISWLSEEHLNRVRSVHRHQVTDYVSRNVEHFNDKLGISNQFQAQISRCTTIVQQLLTKTGAADRLGLPMTQGLDTYAAADERDSMETALKLLYGCLKTGADAVSKFANDLNTRRARWLALASQLAACPLTRGLNSDIQSWLSQVKEGKISGAGLDTLARADGFKIPSISAMINDSNLFFDAATGMEDRQQDWTCLVKSRSDFALSDRFVIGKCQVLLIDHLRDFIGCFLSSRRISVLRSIDAKGDGSGPTRVPSRSAQIRLAFWSMASISSRLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8X8</accession>
    <name>A0A8K1C8X8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8X8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="54144" checksum="3E7AC41FF6A9A34D" modified="2022-08-03" version="1">MGVDAAFINQDLKAPVHPIVAVDKRFCHNHPISVLIPQDILQDPNHGAIYEVAKDEFGQHSVSNHNKHNKDDKTSHDPSHGAVHNIVQKVTGHDKHDKIGQNEIRHNELPIGGAHGYHGTHGVDQNENQVGYDKTQHTGVRNAIHDAVHGTDRNEFNEFGHNETQHGDTHEQTHGPAYGVGQTVSSHSEFDQYELGHNESGHGDLSRGGVDLSAHAVHPNEFGLNDIRQGAVRQPTHGESHGIDQDVTGHNESRHGGLGERTYGVLHGVGEFGHNKTGKQEKRGFGKHGLSKDDFLGKAGRGPLMFNLTHTALNDRDNHVLKDANGKPIVYLAEKNRIIQRNFVVTRDADGEDKMFDVKRKHLSKSPVRADFDDLASGRSCRLGAAVLEESHGITALLWLDVGDGKKEKLPVGRLHLPSGSHTDPNVARAADNHHKVTDAVHPVTKQHKDSDGRLGKDYQLDLMPGIDVSLAVLVGMVTVACADHKRPDDDNAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C926</accession>
    <name>A0A8K1C926_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_010273</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C926"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="31"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="11">
        <location>
            <begin position="452"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="536" mass="59982" checksum="DFC022BD37A41911" modified="2022-08-03" version="1">MTTVAALAPSATSATPSPASALLKPRMLKHFQVEHTLGAGLQGKVKLGINTETQERVALKIIDTAKLNRKAMVNVYREVEAMSRVQHPYVLRLLGVFDDLPYVKKNGTTKQVILIVLELATGGELFDFMMYTGCFSESIARAYFQQLVSGLEACHQNGVYHRDIKPENLLLDDQFALKIADFGLSGLREGPNGAIFELYTQCGTRSYMSPEVLSCMPYEGEPADVWSVGVVLFIMLAGFPPFQIATRQDWWFRACAAKQYEAFWAAHERSATFSPGAKALLTRIFSVNPQERITLQEIKSDPWVQEITVSAEEFRAELVARKQQVEAEKHKEREQKRIQQQEQQQAGGKQFGDEFDPFNASTTRSVPDHDSEVFNDRLSTTSTMSTISTISTMSDATLVSPAAPLYPKECVALYTSFQSRKAPVELQARVEKALTDCNARFVAKKDRFKTKAVMESELVSFAARIYTLPNAPERCVVEFRRTSGNCFQFQNAYKKLMAELADLVWDPKDDTTESESAEANIPPIAEEPISDDPMMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9C4</accession>
    <name>A0A8K1C9C4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04011">
        <property type="entry name" value="C2B_Ferlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04037">
        <property type="entry name" value="C2E_Ferlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037720">
        <property type="entry name" value="C2B_Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037724">
        <property type="entry name" value="C2E_Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012968">
        <property type="entry name" value="FerIin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037721">
        <property type="entry name" value="Ferlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546">
        <property type="entry name" value="FER-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546:SF33">
        <property type="entry name" value="SPERM VESICLE FUSION PROTEIN FER-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM01202">
        <property type="entry name" value="FerI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1994"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2022"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2051"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="265"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="511"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="698"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1055"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1208"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1496"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1678"/>
            <end position="1809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="424"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1386"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1819"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1885"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1394"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1822"/>
            <end position="1838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1891"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1907"/>
            <end position="1916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2085" mass="231609" checksum="16205C249A9F487C" modified="2022-08-03" version="1">MSTTQRLTLTLVAASGVGRHATSNEAPQAADIVCEVCCGEHTARTNAKKANTEDWGHEVKFDVEKGLGDTAKLSLFAVDDDDDGKDELVGEAVLELSTLMPKEKTQMELPVLAPGTSDAAGQLIVDVLYDPEYVEVEEKKTRTSSGTALPSLAPSKPDVVSSPAKTPATATPPASELLLSPKATAAVKSAAVGSPSKTPLSPKTTPAAKAKAVESPSKAPRTSLARSTPLSPSAKAAVKSALSVSPSDASATAEEEKAEAAAVVVPSDPPLTAKPPNFLIVTILEARNLIARDGTGENATSDAFVKLSCTKNKPQRTKVIRESLHPKWRQRFFFRLTPTRQVLDLVLEDEDMITNDFLGQCSIDIEHWMTHFNQDKVVMWIALEPRKAPGDVSVSDISPERNMNYGHGKICIAIETRHIERSLDSLEQGEQDNVTIVPSSKSSKHTTGMTGDNGEDESGGRADGGEGEVFEVQGGEQNEGGGNEEDAAEEDDEDDESVTKETEEDIKKREEEREKMFTELSNVQFLSGDYQIQVRIIEVRDLKPMDVNGLCDPVVSVECLTQRQHTSVKQQQLSCVFDEYLYFNFKNLDRDTAQQGSIKITVLDADGPGSLATSNMSAIARICSNTIGFFTVDIPYVYFQKDHEIHRKWVALVGSGKDNSDLIQGYLLLSIVVLGPGDKLKIHSPYEDKEAQSSDVLSKNDINSLVLIPPRVIQTLNYLVVTIYQAKDLPDMDQNMLKRGGIDAYAVVKFAGDEALETKKITVKGSNHLTVEFNQELWFPVLLPCMANLISISLWDWDLTMDELVGNSSPYLFSQVQNHPTLFEPHWTNLYGPPIGYTDATAERKFMFSHPKLASTYRGRMLVSLRVEDGSKSVTDRPHTRNLTAALPLPPTKSYTLRTAIFFGTEIPRFVSKMRWNYNSKMSLKISIGRYQVSSSRVDNIKGLCHWNQYLEISDVKLPADLEHVPDVFIHLVRQQLNETRYICYARFSARELFQSVDSSPDELKTIPSPRWVSLLEDPVMDDLKDHDFTGNVLMNIRLEATQPNIIANELAQRWREHAISSQSYTKYTLFVHVFQGRALPAADSNGALDPYIKVTCGGAEGKVSARMATRDPCYYETVSLDVELPQDRAFLPMVSTQVFDWDQWDADDYVGSAKFSLNDIPVLTSSDYNKKRSNGEYSPPRPKWYPICYAKEGDTDGELLLSFELIRKDTPGIVIDPPESIRPPMMDQFLEIVVLGCRGLQPVGFMPVNSPFIKFEVGEITKKDGMRYTNPSSKPSGRNPNYLERILLPIKVPVDALYAPRLNISVFDQLLGGFYKPLLGICSVDLSTKMPMSNGKRNPLYKAIRIEDFCGNPYLDKPIDFSTFPGTLPSSIVKENDEAIAIMSSGRGSRGSRASEEIKPDEDTGAGIVPLMSSLSTPIEEDYTDDGDDDTPHYLRGRLLLDGSLEDELNTAPFESYPLFRGDMLVRKKFFGGASTPDFRSVGRFKGMIRLVKTKDEPPLFDLDQFLTPQPYLIRVYVLDAQRLQPKDENNNCDPYVRISLGDGRKRHHMINDRENHKKETTTPKFHTMYELKAELPGASELRLEVLDYDFFAMPTIPKGISNGITSVGTTVGGDDFIGATLIDLEDRWFSAKWQQLGASGDRYEKRKPLELRPLYAPFSALPQGQLRLWVDILTAPEVKICKPLDISLPPPRQFEVRVIVYRAKNITPGDVFTDLSDLFVKCWLQSRDDKAQTTDTHWRARDGKASFNWRMKFPLELPIDEDNEADKGYLHLQLWDKDLLYDDCLADTVVDLSVFLKQAYKANDIVNVFAKKKQVRIRGATSSQPRSGQPDYSSMHSAEVCAPPNSDSVVISVGEDLRRPLLGEVPMYSSGAEQSATLMVSESHGANGANGTNGSLPRSQPHQKKSSDKHKESARTLVQSFKQRFGMGDDPEDASWLTFTTRDPATGDRVRAGELLVSVEILPVAVADARAAGLGRSEPNNFPFLAEPADRLHLAAMWNPLYVLEALMGPSVYRAFTSCVLCASIIALFIFAGPLVNVFVTFLELVPEPYGWVVFGIALALVIGSFWYFLYRCRRAVASISTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9H6</accession>
    <name>A0A8K1C9H6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9H6"/>
    <dbReference type="OrthoDB" id="116162at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="381"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="602" mass="65433" checksum="32D495C628BB4526" modified="2022-08-03" version="1">MHLRFPLPEGYFPKFELTPDESVSYKDLVAAIVKQTRREYSQYVGKGERQVDSRTWNHAKTKDRINIYKRRSEYGAAPVGLARKTHSTPNGSMCSHSSGSMDSGSEASFSTESGARQNYSTVMTAGFTSPGSVLLAKSIKDKDGDGESGIRARLSSTQSHQSSNSGNSVRSSRAGSHVGVDVDEISVMGRGHEPAMLAVGVLEGTVDDIVYALHDGTALDIKGAATLTGDDSLIDCAVLHTIKQNKTTYLGLKWKLTRTPGGNRDMCFIEYVGVALDSKGERYGFQVLESVKLHQCPAFADNSIIRTDISFCYLFRESGQPGIVDVFMQGSFDSSGDVVTAGGVGDSRSTMEMLMSVETCMDRAEAKKLRDLVAKAPAKSNGSGSHCSICRSKPGLLSSHVTCQGCAVVICTKCRLKKVILAKNGGKQKIACCKICVMNVNEKSPFEGEVISQHEKPPSLKAIHRKTADDDLALIDPLKRIGRTNTEDSFAETDYSASMQSLPSSSVSSSYSDIEEIYTHSPADLNMSQLVISESSGRGHAQQMVLPPVPQNMPRAAPQQPANMHQHRVGLYNQMLELQMQAEKTYNLTSQNAAFMQQQQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9P5</accession>
    <name>A0A8K1C9P5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9P5"/>
    <dbReference type="OrthoDB" id="103805at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="166" mass="18625" checksum="2A1E270A8BAF6BD9" modified="2022-08-03" version="1">MYKMVRSNAEYCAILKANSKRDLQLILKYFNIPITEQNFYEAYQRATASKVEPNEYIEQSEIAEKHCFQMSSYKQVSIDVSTATAKKLALGKVVNITARELQGNDEKLWLHPANYEKEMPSLVSAARQGLKQLTGVGMAGKVAKGSPEAKARMATLRAKRKYGKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAE9</accession>
    <name>A0A8K1CAE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAE9"/>
    <dbReference type="OrthoDB" id="65166at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="191"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="96569" checksum="0CB9BEBD82BDCCBD" modified="2022-08-03" version="1">MGSIRKRSALQSSNASAYNGSSRDVQSIPREPSTFRGKMRIAFNDPTQGDNSIDVALCVTLDGVQTVADLDNSVVFEASYRLMKEIIWDHTEQTVSFVLDDETPAVCFEFTTLAEVEAQIAEAIQHPDLHKQPEQVFIGVLIGKNIPSPIQQRRASTVSLDSSMSVLPATKRRELLSHERPSRNITSRESLVKYHGLLMKNGGKYQLTKSWNQKYVALVETAVGGFLCYYDKLAHCPGMTETPKERRVVDLCAVICIRRRSTVASAPPFAFDIVTLYRTWTFAALDAEEYDVWLNLLSDAVEKHSSMAPDQALRYPLKGVVDPLHNLPSKDDSITLEISSYGVTVCAGSEGVADIYSWYFTDIQKWSVVVHHGETCCLLSCLAAPAGSETVPGYHEFLFLSNEAAAICHTVEFFVSKCMAKLEILSVAYIEPSTRPRRPSSSDQSTHSHLHNKSKPTESKQVVIEAVQLHPVGMSAEPVVQETRAATAPSLTTPSEWSATPDLVQNPEFPSSEGTQANEERAIIEPIEKQRDFIPVLIELPVSTLPRQASGLLVDQRAGVYGSRKGSFNPFDNVDDEPEETTFVIRTHPAEPLDTTVERVPSAHQVAFNTMNHQSISDDASTFCDVSGLDIASDIAVVSEDQLQPNEPCQDVEADTSALEEPTTTVALEDIVLEEPSQAAGDAENDRFLSFEYVECVVREHVELLNADTEEESKNESFVPDDEFEDVAESSFGAFGLIDMDDGVVFLENGAGDEDSMILLEDISLDDVDSLEPMVQCIDPDDVLDEDTEMEPSANTESSPVVEEANDENFEELTTDEVEELLRRNRIDVQHPRIPIPAYSQRHSVTMETACEHDAMLPRRAFFWRGCRLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAN2</accession>
    <name>A0A8K1CAN2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Replication protein A 32 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAN2"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000168">
        <property type="entry name" value="Replication protein A 32 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000184">
        <property type="entry name" value="replication protein A 32 kDa subunit A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="9">
        <location>
            <begin position="78"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="10">
        <location>
            <begin position="172"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW59213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32478" checksum="04B3C52E5C2AB227" modified="2022-08-03" version="1">MNYGSGYEAYSNDDYGGGGFMDPSSSQGASQNTPSKGGRGGGRSRESQTLVPVTVRQLLNRTEQDDVIRVDNHEISSIKVVGILNNVSPHSTNVTFQLDDGTGVIEGRMFLHSDDVDFAEAEMAKFRDGIYVRAVGSLRTFQDKLSLSCFAVTPVEDFNEITHHFLEVIYVHCYNTKGALQSSTATKSAAGGDNFQMQQSSWNQGTNSTYLGQSSGGMASMGSMDYNMDSSFSNEQKAILDVLGTCTSDRGLKIDQIFMQLRGQMTEHQLRDALNYLTSEGHVYSTIDEDHFKRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAN3</accession>
    <name>A0A8K1CAN3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">M96 mating-specific protein family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAN3"/>
    <dbReference type="OrthoDB" id="75145at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="49036" checksum="62580A598C3793A7" modified="2022-08-03" version="1">MRPSSPIASLSAALAFLGDNALDDVEVENLGARELLGAADDSLDFLASLDALDVPAIDNVPSDYQHRPMETHLSDSQHAVSTEIKTPKEKKKDMRTSRREELIYLRSTVAALEGQLDKLRQQRQDPEKPSADSLVVSSMWKGVASRQHEQRQNAEVENTKLRAMLEENIRIAKALERLLRKRSCLELIPTPISVVPKKRTLANRSTSPLVQDDIMGELSDSLIGMYEQVDTVLKSNRFRGSQPVRDFGLRTDAGTGTSVEIVETRVMPFNYKATAAAMWELSLRPESCSGGHRISSIETHVATSNMISRSITSTFATPQMQSEFGAKMVERRFDEADRVVFVLHLLKEPKVVAGKPMDGIVLRHRGWVVVEQGPGDSSIMKVFHIGTPEIYDAVAGHRKMVGELTNFVLQTVDMHLDLDQRELENLLLQHSTAQYNGNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAU4</accession>
    <name>A0A8K1CAU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminodeoxychorismate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAU4"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36986" checksum="BC363A07B6F68700" modified="2022-08-03" version="1">MAMTASMAMTAVVKMTALNERICVEMATDEAPETPSARAFLMAHPRGVYTCARAVPTATQFCLVLWRFHLDRLAVGWRSERQETGDTRALVGVLQETSTRLVTDALARWAEAEKDAMVTVLWWEENKDEVNVRVHVCTMPQVRSLTANVLIHGEPRINPLCKHSRWIDQRVPLEQHMRDVTTSLRVEHGEDFVLNEAILSSPLDRDGVSERRLLEGLITNFFVVKDDVVITADADMLKGSTRELVLRACKELDVPVKLEAPTVKDLRASQGAFVTSCVQVLVPVVNVFWSDVEGGQKYPHLSISTSHSTLALIERIRNHIQSHWLKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB32</accession>
    <name>A0A8K1CB32_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000078</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB32"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="382" mass="42299" checksum="CCDC70052CC496E6" modified="2022-08-03" version="1">MTTVTTPKLFTPIMLGGKKNPIQLNHRVAMAPLTRLRAGDPGVQPDYAATYYSQRSTDGGLIIAEATNITPYGRGYLGSPGIFNQEQIDSWKLITQAVHDKGGVIFLQLWHTGRIGHPNLQPNGELPVSSSTNMPLSENRASTTKNGREPMVKPRALETDEIPKVAQDYRKATENAIAAGFDGVEIHAANGYLLEQFLQDGINDRTDKYGGSVENRARFLFEVIEEVLKSVDSSKVGVRLSPYGKSCGQQDSDPAATYGHVFEKLNDYDLAYAHIIEPDPVYDNNEMTPKEGATKFFRQIYKGVYITSSGYERDSSIKVVEAGDADIVAIGRYFISNPDLVKRFELNAPLTPWDDSTFYRTGEKGYTDYPFLSEESESISEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBP8</accession>
    <name>A0A8K1CBP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBP8"/>
    <dbReference type="OrthoDB" id="168130at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="855"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="898"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="920" mass="102207" checksum="B0B2D43B1C0D0D2A" modified="2022-08-03" version="1">MVDDDDNSTFSIMTTPPSTQVVIMEGMLKIRGHGVPMMRDRYCVATWEGEVDTAKAVVLRTYKTQAAYAQKPDKPASEYTLKCLSDWDGKGKLRTYSNGFIFETNEQKLFHCVAPSEEEKDKWTELMDTVVTPRTVVEEPVIQPKKKVRPPSEGFVFEDRSVDVHGFADPDDIGDAEDLFGDDDVGGLESMMNANDVKVMKLAAEDDDKMLFRSSSGSLTVSDLDQQDDRRTRLQSSQMVEEPADWGLYGESDDIGNGPSSRYDVVDNPVVLLDNDILSGTSKAPVLSSDAFLFEESGPTFGAVVVNRLATDDADDFVDPELVARQEKKKKEKQLKRVVQKLESNRDLYAEMAAARLRSMRKDARQPRRSVSHRRDNWSEFDDDEYDESHAGYDGDFDSFRSSRSLAESTTPSVAHSGSNVENGEVEDEDEEARRKRERRALRKMRRQEAESADTTESNSSDLAMVTFEAAEHEEDDGFLFGDAGVPMIPSSVIAEETTGITGEDEVRARKREKKNKKRREEAVQDDEESVVESAPYESNGRAERANSEPTAEELEEERRREKQRRKEERRARREKERRAEEEAAAAAELARQHREEMRRQEEERYKHDRHGRKEKKKSKEKSSLEKKAKELKKREAALQAEAERLKQAEEELKAEAERKDRKTKRRDKYTSPTERIQRREKEAEALASEMSNALVLVEIPPQTAPAAMQAPVTVTVASVPTEVAPAPVSTPAVPVATSPEAQTMPQASVPVETTAPAPHSAPAIHTTAPGSVPAAPQSVPMQMPMMAPPSFYPGYPPAMMPQYQPYPAAYPAMPYGAAYPPMQYAPVAPAYYQPPVGYVPGAYPPTMTPPVSRAMFPPGSIPTGPTAEEEPPAFIGPSLPSPKAHQDGPPPPPPPSTSSMAPPSSTASILPDLPDIVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBQ4</accession>
    <name>A0A8K1CBQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBQ4"/>
    <dbReference type="OrthoDB" id="74158at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF79">
        <property type="entry name" value="MOBA-LIKE NTP TRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="660"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="698"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="733"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="761"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="479"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="631"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="834" mass="90129" checksum="8B294EDAC3734286" modified="2022-08-03" version="1">MASYEALAVPRQQIFSLDVAQVSDRVALSTDELLTGLATSRPSASSLAPGQAEAYSVCLLVQADGESGRCRALQGLEDGPTVLELLLRRLLQPLCVRLVVCGVGDAVGPELDAIVTSEYDSIVTVLHETDTLCALRKACEILVDTKSTQPLVVMQTDRAFDTLTIMELLLQHRNATILTGDLTQVLSLVDHKDSEHLPRPMGLWICSTLAIDRLCRSDPSVFKGQDTTVTARYVQQWLETLVGDCACQDVMASETFNWEEVVDSGKDDQVTLVWRFPAQDNMDVKSVKRSSRTSRGSSTFEASNPVLTLLQQQLADEGVNAELYPISTRVSYESMGEGTTERSTERTPLLLNESTSPVRTGSLESTMLSEIDLLDSAQVTEASSQAFLIQVETPSVTSGTELILALPETALRAIEASPSLESIEMRPTGGRRFSVPRARLPSGVKEITLEAILEPTIKPNVRTKRLSVMLHVHKQVPTIGYIILITAVCAVSSQGAALELLMGVPPLLKLFWRMTGASIAFLPLAALSVYKDGLPAILTHKKLSFLVCAMSYTIYNGTFLIALSLTSLGHAYIFCNSHSLIMVLGKLILRQPLGPLELIGAALGFSGGVITTMDHSEASPSESIVQASPAGDLIAFAGAFGGVLYLICAKQVRASLDVRVFLFLLVTSVWTLLLPVLLWNRHKLGVQLSNITDPHTGLFGWIHHIGIELYLVIIGSMCGTMGFITSLKYFDPLVVSVSMLTEPVVATTFGILVGVDQIPGWPTFIGGFAVLLGCLLVVIASHNTTVKVDVSDTLTKTRYTSARSVLLEQGADYPEDLTTGAVRPSTTGRYGSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCG5</accession>
    <name>A0A8K1CCG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCG5"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF9">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="45503" checksum="52BD16C2155D39EF" modified="2022-08-03" version="1">MAHNHTTMGPIMALGGDAYDPENADNAMYKWVGLGIVIGSAILSNLGVNVQKLSHVREEELPAFKRRMYYTRPIWIIGMILIVLGAIGDFEALGFAPQALVASVGGGCTVLANVFFAHLWLGQILTMTDVIGTLLIIIGVVLSTVVNEPDDKMSLEELEMQFFQPGFLVYLGVMILILGVMFGEIQAISRLPKRNNMAKHRRLPFVYATASGIFGSFSVLLAKCASILLILTMGGDNQFVYFTTYLFVGGMISTLVLQTDLLNRAIMVGDTVSVFPMFQCFWIGSSVVGGVVFYEKYTRFTVFEWVCLPIALGFIIGGIYLLSKHGEEDLAHLATSGPNGTPSPALSRKGSHFTSGHFGALMPLSPTHRASLIFTNPKQFEEDFKDENTPLKAEKTALIDSDQEQYRQHERIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU7</accession>
    <name>A0A8K1CCU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000024</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCU7"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="13">
        <location>
            <begin position="41"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="12">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW59982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="76243" checksum="D61991C25F86374A" modified="2022-08-03" version="1">MAMSSTGEAPTKTALEVYKQSFREYLWETHVVSTEEELDQLVALLHEPLPVSFRLNLHHPDTERVKKLLATDFQFPSNQYFHGNIPVDPPKPIPWYPLSNVAWQMDCGRVALSKTAPKYADIKKFHACLLESTEMGTIDRQEAVSMLPVLFLNVQPGHRVLDMCASPGSKTTQALDFLADSSNSDATSTPLRGMVVANDLDKKRAYMLVHRLSRNTLRNAVVTCGSGITFPGLYDAASKTLQPTNVFDRVLCDVPCSGDGTLRKSQTLWKEWHIGQGLTLHPTQLSLGLRGAALLKVGGVMVYSTCSFNPIENEAVVAELLRRCDGALELLDVSSSLPSLIYRKGRTQWPVGWRSKSKSTHKGHVFNHAKSGEEEAARLHDWYSSYADLPQELRGQRVVRSMFPPTSAEAIAELEKTLRLVPIDQNSGGFFIAVLRKTRDLPGENQEGLAPLDEEIAIPPPEYVCKLCGEKGHFMKNCAKYLPEDTYEAGPKPTKKRRTDEEQTKTEKARETLYRPISDEAWTMLQTFYGITDSALRARFWCRSDSASTVNYVDEDIVGSCLGGDALEIVNTGLRVFTKVTERGEAFYRPTEEALGFIERFLNKRLLTFTRGDLEQMLGGNAHTPFTSLSSIAQSALTDATIGPAVAQLDVNKNIAINVWIGNGAVLPRVSKTMKSEVALALQRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU9</accession>
    <name>A0A8K1CCU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCU9"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="212"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="630" mass="71386" checksum="2789FE0EA1131DE8" modified="2022-08-03" version="1">MSSASDAKSPSGVSEPLSFQPNVTSSTKGGDSMWSRLFRPFSLESPMVHRFLPKLKAGRFLIEVGDKSEWRQYEIVLAGSSIGDLGLYYYGSKADQAPVGCIHLHSAHVDVLEEVLMVITQDKTWFLCANSGRDASDWAEEICAAIDRVSQAILLQGNGPRSKRRRLSSHVSAVTLKEIQSREPRARVDEFLEIFVRSNHEDVRMQAMEGALSWSCMRNLAWRLWLDVLPLDMAFTEWIPTTRIKREKYASQREQHALFRECLKGKQNDEEFIAACETTEDSLLYSIFKDVYRTQGSMDYFRSASVQCMLIRILYTYSNAHPGISYNQGMGELLATIVYLLHTEQWPGNSKSSKSSALQESSQLTSNRTSLERLIDDEDASYVYVESFIDIQDDTTYLDREKFLRLVPFTGGVGKYQDCCREAAEEIICELTLPTYIEHDAYLLLEEIMFRMAGAFCPEAARASSNRTPKSKKHKRSSKSTACTVTLFASEMASSPLYDQMNAIHHHILSRCDPPTARHIAALGLEPQMFVLRWVRVLMSREFEMAQVWQIWDAIFSLTPSDFSFINLLCVAAVREFREEILQVEDATAVLLCLRDLSDKVDADRLVDNARELYDALMIAAAVEATNGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDG4</accession>
    <name>A0A8K1CDG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDG4"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF173">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDRATASE-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31572" checksum="D6D825469411DEBC" modified="2022-08-03" version="1">MVRSTLTRGVGAVLRPARNAAFSNMRSMSSVVTLEKQGRVGILRLNDPKRLNPMTGAMGQALEEKVAEINKRADEFGAIVLTGEGRAFSAGGDMKFLNARIEDTPSRNSAIMREFYGRYLSLRTLKVPLVAAINGPAIGAGLCITLFADVRVAAEDAKMGFTFVNLGLHPGMASSHFLPQLVGPETANYLMLSGKVFDGKEAERLRLVSKAVPNDQVVDEAVKIATEMATASSTAVRGVLRSLRAKQDAGLDIALQREADAQAHSYASPDYAEGLKAIAEKRAPQFGDYEHYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE05</accession>
    <name>A0A8K1CE05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE05"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="86" mass="10287" checksum="08589175D895F288" modified="2022-08-03" version="1">MGKPIVFKSALRQEVLYAAGNDLSYDRSRRNLFTWQSEWSVDQAKEQWLLIPVDGQHDRFYIKNVCYEEYLYVAEYTPFGREDRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEU9</accession>
    <name>A0A8K1CEU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KIF-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010791</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KIF-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEU9"/>
    <dbReference type="OrthoDB" id="409897at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022083">
        <property type="entry name" value="KBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46321:SF1">
        <property type="entry name" value="KIF-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46321">
        <property type="entry name" value="KIF1-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12309">
        <property type="entry name" value="KBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="623" mass="70302" checksum="B3A1009C4C10FF88" modified="2022-08-03" version="1">MTSKAESMIPEDFTALLRHVEELAATPNPDATPYASHYQSIEILQKWLTTPMDPLEEAIARIKLGTTYLHVEEPHQAQPMLEQAATFFYPKLLEYIKTIDEPSEQDEGKEDEPIATQIQRLLTQLPGIELPEELRSSERAQFAHYPLELLNQAGILWSNRTQPRRALCCFHACVQLASSIDALSCKSEEEAEELRSTSRSIQAHAQFYLAQVYGTLQLADASAQACLATLELQLQGFLALLAQSKAPNSRGETTVNDWVKNAVRLAEYYLETAYLHDAATCLYASEYILGQLCTQPSDEDDEERRLRLGEIHMTWAKIHQLTLQEAVWRQDTPLPPNTAPAPDQDAPIETKSLERLLGPADASDLKSFSSLLMQVTAVGAIKSFDTAREVFKQGMSASDAALQIFSLDGFVTAHVRLRQLQSRLYRRLVAFETDRKRQIAMHLRRLGLLTPLLTAELNPAAYTALIQELLYEAAEVATELHDLKQLHKPNEANNTYAFKAIQWYRDYIALFYPSGPARLVLPSQEMTPEEFKAVLHGYFALGRVCGKVWFPQDQEKTVACWKQAIESFEAVKTLVKLYERLPGNEARASALRTLYGAELVMCDDMIELLPEKINQLVYNGKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF87</accession>
    <name>A0A8K1CF87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012654</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF87"/>
    <dbReference type="OrthoDB" id="152370at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="126"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="581"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW61463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="700" mass="79299" checksum="644E037F7CB45361" modified="2022-08-03" version="1">MPTTAFRTGPAVRSFEDPTKSKQPVKLTKTKSIKPKKLDAGVVVHDLTERHLHRHASTLIATAGRDAAIRECREKVEMISSECRLRNVKYRDPHFDLSERAGTCLYGLHQMADENDEGVHMPGGIKRVGQIFDNPKFIVDGIDAGDIKQGAAGDCWFLAAIATIANKPELLESICVARDEVVGVYGFIFFRDGDWISEVVDDQLFIAHGDYYHAPDEVRRAFASEQQYVQSLQRGSNALVYAHCEDSNETWLPLLEKAFAKVHGDYSAIEAGFTGEGVEDLTGGVTSEVICSDILDKDHFWTNELMHVNKELLFAGGIDRLGVAEVRGILTGHAYSVLRAVEANGKRFVQVRNPWGKTEWTGPWSDGSAEWTAEWITILNHKFGDDGSFWMSYEDFLETFTVLDRTRIFSSEWSVAQCWTRELVQWPNKSFAEHEFRVSLEKDGPVVIVLRQADTRYFQGLEGQFDFQLHFRVRREGERKYFARSSHSIIMSRSVSMELPLTAGVWRVSYKIRRQKRGRASRTDYINEFREKQSDKFMEVAINFDYALNLHVVHGSKHELEDGDEIVAVPVPEVDDIVTEQVEEEEVEEEAEPEMEKSNQEEEEQEEAVEEEEHEEEEEEGEQDEEEAAKAKRAKEQVELLDAIVVVGIRVHAQDPGLQVSLVKSAPTTSDWALDPDDSIVKRFHARTGGLLASISQLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH47</accession>
    <name>A0A8K1CH47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH47"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="57500" checksum="CDCFD1190169DF69" modified="2022-08-03" version="1">MKHYADNRSWPRVMSVCFLSALPCLVMNVLLECIPLRPISEGLATSQTFWIRSSIGLHFIAFTSLELYRLFVPSIPSTLRQIVVMTIIVGTGTTITEYLCALWLGYPVPFCAVLTAPMFMTLMVACVVFSWGKFLKENKEVFLELQHFHTVISIIFSLAFIYPAFNYAFVCFNSTQQSWFAFLLPIIKLAVKNCVSPFVFHAFFVAICMQSAISYRTTAVLMLTDFVHAGISLYGISVLTKRIQDTRAKVFYSHRKNTKSELRLSWSELPDHIFFLVKSDPKLQEVHNIRVSSRQTTQTRKSTSPSVVTPLTVVPVEPSGAQPSGPVLQLSFTQPTTASIPDLVPKAEQQLLLQALDENERAAYVGSVLKLLHMIECLVLIEFTELIIPFVYSVYLYATFHLPNHAYHTQLRDLTEDEIRRVIGNNLVYATLELLSLVILQIHLYRKFHISAAHQLAYVLERQWISVQLKLCSWFIFIIQFSVDHFGADYSFRFNWLKNPSPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI07</accession>
    <name>A0A8K1CI07_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002365</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI07"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF620">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="46"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="366"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="613" mass="68701" checksum="F5349CC91B2C1B67" modified="2022-08-03" version="1">MGATNDETLPLLAKAETPREVSAWDMKVLLKPYFWPTTWSLRLRVIASFGFMFLSRGSRILAPLFLKEATDTLSQTQFTQLPTLAILLYCLCLFGFSFSKQLQTYIYMTVKQHAYQDVAHTLFEHLHSLSMNYHLTKKTGKVLRILDRGSSSTDSIVNVLCFRLLPTLLEVIVVSIVFIFSFKEKILSVVCLVSVMIYIVFTGLGTQIRLRLKKKRNEHDNMASEKAVDSLTNFETVKHACTEEYELTNYMESVRKVQELQLSTRGLDNAVVSAQQFIQQSCLAACLFITALNISRGTMSVGDFVAVTVYITNIFKPLDSLGNIYNTIVQSLVDMENLVELMQIEPEIKDRPDATLLRIDPQHSTVEFHDVSFTYPSQPPENGLKHVSFTIPTGRTCAIVGPTGSGKTTISRLLFRFYDVRRGIIRLNGQDITRVTQKSLRKSIGIVPQDTVLFNDSIRFNLSYGCPSCTEAEMIGAVQAARIYDLIQSLPNGFDTEIGERGLKLSGGEKQRIAIARLILKNPSVVVLDEATSSLDTVTEKSVHEALEVACQGRTTLIVAHRLSTISHADEILVLQKGVIIERGTHDSLLGSEGVYHQLWNRQSHEIEEDTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIP2</accession>
    <name>A0A8K1CIP2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002366</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIP2"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.530">
        <property type="entry name" value="DNA polymerase alpha-primase, subunit B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043034">
        <property type="entry name" value="DNA_pol_alpha_B_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013627">
        <property type="entry name" value="Pol_alpha_B_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08418">
        <property type="entry name" value="Pol_alpha_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="10">
        <location>
            <begin position="227"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="8">
        <location>
            <begin position="358"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="637" mass="70165" checksum="EC561D6D33918099" modified="2022-08-03" version="1">MALKIDLDAEAVRQAFASCNLDVLDDAVHTCIAICAEFSLTADELAAQWDAYSMNHQVDGAADVDKLGVFRSKLAQDKAAKSKEGSAAAASGANKRKHAKVSSTPVIKREIKTESSQDPLNALYNMKSPEGKNARSFASPPGKVARTAGLFSPSSMQSPPTTSYENRTDAGKTVSEFNAHLKKELVPMTDASENTEAVSIRVPFPDRNLKANAPYMYTPLFERALALDEQLVEYEELIKTHYNLENIAAVADPSPAQVTVVGRIVCEAAEGKLNASVVQLEGSRKTCGGQRVLLDLSAVPNFQVYPGKIVALEGVYEDTRNPMVVKRFLEPVPAPMPTTEKARLETIYVNDQKRPLRVVTASGPFTTTSNVSYLPLNDLLQIVREQKPDVLILVGPFIDTTHASFRDGLVEFDGMMLGFEDIFLFKVMAALDSILEQHKTLQVVMVPSVRDAHHQYVYPQPPFNKKKACEALGSPEHAKRVHMMSNPCTFAINDVVVGVSALDIVMHLSSNELYRAQARDQNRLLRLCQQVVDQRSYYPLFPPPPNAEAPIDLRYMTQFQFERTPDVLILPSMLNRFCGRVHDSICVNPGQLCKGESGGTFAALTVLPLSKDKITNSTTDEVAHFVPDRTTVDIKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIT8</accession>
    <name>A0A8K1CIT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Patatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_012844</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NTE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIT8"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046470">
        <property type="term" value="P:phosphatidylcholine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001423">
        <property type="entry name" value="LysoPLipase_patatin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01237">
        <property type="entry name" value="UPF0028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="117"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="331"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="434"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="13">
        <location>
            <begin position="800"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="9">
        <location>
            <begin position="804"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="9">
        <location>
            <begin position="831"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="9">
        <location>
            <begin position="952"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="833"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW64222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1129" mass="125034" checksum="8B127F14AAC50B7F" modified="2022-08-03" version="1">MDAWLRFLPLHDQRLLVYAVIAWTLVLGATVALYVWVASRQVRPRPMPQGPPSRPTSPAFKRKRHSKSFSDMQALEKEMMAENAVMDRQDWSAMPLSLQKKCGPEQCTLIYETLSKAFSFLRSEYIDTLAHDLKIHKHRSGDVIFERGKHDGSIIMVAAGEAQLTIHDGDEKRFTKTLTRGDTATSSLSLLAAIVADLDDVSEFLREEVVDKVIGDLSAVCTKDDTVLFEIPTSAVREVLDQYPDSFYRLAQAALSQVEKITARALVDHFGLASSIFTPRSLIDLSDYTRREGDADIAQLIKLVSQPLNAADSKFEAALLECSTLITCEEEKILSKRDVAGSVYFVINGSARIEIRQSSQYVKVANVEAGGEIGVASSFIEHHHPSRIVCKPSTTLLSIPQQTFASFLQSRQVAASCVQHLLRQYSPLVCTADSAFDSVHLHGGESLFDRGDLCDSVFTVVSGRLRAIQVHIQHGKQVETSNELGRGATLGAMDMLAAGRSNSSVFAIRDSQISEMPRCVFDYVVHRQPTVLIHFTKSVAERLPRHGLDKPTNDRGSRSAYNFLLSLGEAPGDEDAKASSEMLPVSTIAVISLTKMAAISTFCSHLHSALKSIGTAGVVSSKKASEVLGDQWLVNSRLGRANLSAWLGDMESSHQLVVYEADPQLTLWTQLCIRQADHILLLCSDSEPPQSFLTDIVPILESAWNRKSIAINVVRIREKDWTLTAVENAKAAAASQSSRRNALKRRLRLWKNSPMLPRFLLPMEKYEWITAFHNVQTPFQDHHPDFLRLSRRITGRSVGLVLGGGGARGLAHIGVLRALEECGVHVDVVGGTSIGACIGAAYALHPHHLNLVQAKIETLSISLSSVMEKLRDLTLPIASFFNGSRFNRGIYDLFFDLSIEDLVLNYFCVSTDIAKSRMCVHHSGPVWKYVRASMSLQGYFPPISEGGSLLLDGGYMNNLPADVMKEERGIKYVLAVDVGSEPRREYYGYGTALSGWWLLWNKLNPFSKTVIVPSMGDVSAALAYVSSEQHKERMKAECIDLYLRPPVNDYGTLQFDKKDEIIQVGYEYALPRVKAWASRVLSVEPEADIVEPDAKITKLDDPSVTEEVLSDLDTRKSEESVSTMASEMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ68</accession>
    <name>A0A8K1CJ68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ68"/>
    <dbReference type="OrthoDB" id="167863at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="39589" checksum="3374B9B4D846DA18" modified="2022-08-03" version="1">MLEGDARRTLEEEAIALVNLSTSHLSKRDMEATSQMKHVMTHHPRVQVHASLRHEGTSVSRPMSLQHPVASDLSMSVFVNGQGKLSAMSGGKTSPDHHAAFEISSLDPVAKNHQMTPVKMEGSDGQGVKRAHCESPTSPVDDKNISMQSLLVTLKKRKLEDSNEATASCLKLPSFRDVFNASKQQQVQERPRATATSPTIQDPQNSPSRVQAEEAHQQTLPAGVIPPPELKCKYRTGKCNNIRALKSCGDYHNLCNYHRLRANANQRKLDRKKKVQRQQVTTGPHSGHSSPIAASSHLAAPPAAAAAAALASLPTAFMMSRSVKASREPVAASFMPFLIPATTGASRSSSFPVRAPLRPKEENAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ72</accession>
    <name>A0A8K1CJ72_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_002118</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ72"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470620" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="10">
        <location>
            <begin position="56"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="11">
        <location>
            <begin position="368"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW63177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="725" mass="81410" checksum="18FD5795E179335E" modified="2022-08-03" version="1">MKLWLLSAVGLHAWLAATSEAQDTWESGDLTPPQTLVPYSTGQLSLCTPRNIDIVAGKPIPTNTWWGNLITCDPSSNVTQPIWPNPFAISVETVNTQSLHGFAMGYPFRYRYFGNLSPSGEAPFYGHVAHKEVILSATEFAGTVPIVRVTDWSDLGVSVALSIASGKLESNIVSGMAFVTGTYTQLSPRIGIQVPMQSINGLSITVGRVVTGRKFLITTVSNLQWVIYTNTDVSLTIETNQVLRTSSPFTGTMRVAPVVTEVPVTVYDMYKDCIVLGGDVAVVSDAQYQFQWRTMGDCTNGLFHYALPHQMETIDASTVREVTGVSLRSTVRGQMRALVTRTTAMTWLFNEPASIPITFYPRYRLTTQDASQQNLLNQLVTDIQSTWSIATTGSFYFNGKAAQKYASLCLMANDPTIVGSDITPLRRCLTKLAAIITPFLDNSWTYKLNYDRVYGGIVSSESFTSGNLNADFGNTVYNDHHYHYGYWVYTAAVMNYLYPKWTRIDDLNRMTRLLLRDVATPNSVDPFFPKFRHYDWYRGHSYSHGVTTFADGKDEESTSEDVNFAYAMYLYGQATGHARMTTISRMMIKVTSRAIQRYFLMEASSTVHPDNFKTHKAPGILFDNKVDYATWFSAERYCIHGIQMIPITPITDFVRTRTFIQEEWDTVLSKEAIVVNGDVSNPWLSLLYANYARVNRAQALPMLQKTEMDDGLTRSWALYMALQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJK7</accession>
    <name>A0A8K1CJK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJK7"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="74585" checksum="ACA4D31869D38B1F" modified="2022-08-03" version="1">MALAAGTSIRALDGFFRLHYSCEVPAPTPVVPTPHLFSSFVLDTNSWEELEKKRQLLETSSSTSEHASEGSHVKIVYFVRHAEGYHNVAERELGTARWEAVEAKQEKFLDADLTPFGINDAQSKGPPAVAVELAKGMPPVERVIVSPMSRAIQTAENFFTPGQGPRPFVAMELCRETLGIHTCDKRRPLHQIKEKFAGVDFSRITDEEDVMWQPNNRETDDELRARAKEFLVQLFDEVEERHVAVVTHSGFMSSVWSLFYGEPFKAANCERHFESFLVMGDILSRKAPVESKSVAARTGKGSGDAPAAASEAIFLDEIDPESAEWSREGMCTTIQRFLGLLPDSKGELLKQDQKIPLYVARVPVGLSSQMTSASRAKAILIVQRVYRRYRLLVKWHVVAFQMLDTARVRIEEREMQEKEQEMVANFRELLMDGFSAQKVSVSGTLKSIHLLLVFKPEQEDCYLTWTPSRKRQARINLHDIAEVVPVLKEGNKHAPKLANKVSHRRGLIIVCKSHHRGRVILQMETKQARKVMLAGFKRLLADLNDFNPTLDSAGALRKSMPRRQSVVKFFAQPVSRKDPLESASSDEEDLIPVDHQVDTPNESKSSESTGTKDQPPPSEEPKKVKRRSTFSRFYKTRFDEPTEEDVASKSTLTRRSSMVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK90</accession>
    <name>A0A8K1CK90_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_008962</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK90"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.380:FF:000001">
        <property type="entry name" value="Valine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000009">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000078">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="16">
        <location>
            <begin position="113"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="17">
        <location>
            <begin position="791"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="domain" description="Valyl-tRNA synthetase tRNA-binding arm" evidence="18">
        <location>
            <begin position="1000"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW64795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1068" mass="120893" checksum="7984EF2FF230F5D1" modified="2022-08-03" version="1">MADQQPPATPAPTEAKDALPPAAPATVAVEAGEEKKLSKNALKKAMRAQKDGGKPKKDKDPNRWAPKKDKEPKKKETKVEETPFVNLTPKGKKKDMTSPMAPAYSPVAVESAWQDWWEQAGFFTCTDEKIKNAKKDERFVMVIPPPNVTGSLHLGHALTVAIQDALTRWHRMLGHATLWVPGTDHAGIATQSVVEKRLLKEEDKSRHDLGREKFLERVWDWKNQYESRIHQQFRSVGCSVDWTRVYFSMDDNCSRAVRHAFCKLWEDKLIYRATKMINWSCKLKTALSEIEVDYIDIEKRTKMIVPGHNPDRKYEFGVLTSFGYVVEGSDEQLIVATTRLETMLGDTGVAVHPEDPRYTHLHGKFVIHPFNGRRIPIVLDAELVDMSFGTGAVKLTPAHDPNDYECGKRHGLEFINVLTDDGAINENGGEFKGMMRYDARIAVEKALTEKGLYHGKQDNKMRLGICSRSGDVIEPLVKPQWFVDCTQMAKDAMDAVTKKDLRILPETHEKTWFRWLENIRDWCISRQLWWGHRIPAYFPRVKGEAWVDPNSEESASRWVAGVSEEDARKKAAKNLGVSEDDIILEQDEDVLDTWVSAGLFPFAVFGWPENSADMENFYPTDLLETGYDILFFWVARMVFMGQKLTGKLPFHTVYLHSMVRDKYGRKMSKSLGNVVDPLEIIAGCSLEDLFKKLESGNLPQKEVEKAKKGQQLDFPNGIPECGADALRFGLLAYTQQGRDINLDVNRLVGYRNFCNKLWNATRFAMSNLEGFSASDEDFKTVLTNEAVSVRDQYILSRLNYTIGVCNKAFAAYDFGDLTTALYNFWLYDLCDVYLELAKPVMGGSDEKAKLTAQQTLYICLEFGLRLLHPLMPFVTEELWQRLPGKRSAPSITVAQYPLAVDGWSNPEVEAKMELIKEVIHAARSVRAEYGLVNSVRPQFFIKCADAEVQQIIDTQLDDFSTLAKAGESKTLLDEEPPKGCAIHSVNEKVQIHVLLAGLVDFANEISKLEKKLTKIQPSIDSLQNKMAKEDYAVKVPENVREAEAAKFEALTKEKEGIENAINGFKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKA0</accession>
    <name>A0A8K1CKA0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKA0"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="15"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="261" mass="29742" checksum="9141C5A35C612C38" modified="2022-08-03" version="1">MTDEAIERILSTGVHHYHVLGLSLPTDATALAPSTVVRRRYKELAIRVHPDKNASPNAEEAFKRLSEAYECLANEHSQRVYLVRLLAQTSARRGAKRPRPPPPRAPSQRSKPPPPPRRPKRPKTSPSPPPPPTPPPPPRRRTPEEIWQAFQREEEEQARREFHAKGFEREYKAASSPKPVSNEHDEAERTRVLESALDDKASRWHGWTKRAETTEETQTSSPPRVICCLLCRRKFPSEAALSRHEELSTLHRENVAKDSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKB2</accession>
    <name>A0A8K1CKB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rho GDP-dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012857</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKB2"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000004">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24186" checksum="FABFD0DBD660EEC6" modified="2022-08-03" version="1">MSQSKDDTAMSDDGFHGPADQDEYRMSELAPTDVGELMRLDAEDESLRRYKEQLLGSAAHGDLGDRSDVRRVVVEEFKVVFEDGRQDILYRLDTPQGIEYMRTTPFAMDEGVRYKFAITFRVNHAIVSGLRFRNKVKKTVLSTTDEIVLGSYAPRSQPYEFLYPRRDWMDAPSGMFYRGKYMAQFRFIDDDEQEHLKVLYTFEIKKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKV7</accession>
    <name>A0A8K1CKV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKV7"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000008">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="9">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="259" mass="28182" checksum="EC464A86409F0FE3" modified="2022-08-03" version="1">MFEARLPQGRIVKLIVEAMKDLISEGNIDCTKSGIALQSMDGSHVSLVSLLLRAEGFEHYRCDRNISLGVQTASLSKILKCSGNDDALSLSAEDSGDALNIMFEAASGDRVSDFSLKLMDIDSEHLGIPGTEYMATVRMSASEFQRICRDLQTMGDTCTIAVGKEGVKFSVSGDLGAGNITLKNNTAAEKESDRVIITMEEPVELTFALRYLNMFAKATPLSETVTLSMSPGIPIVVEYPIGDIGYMRFYLAPKVEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLA4</accession>
    <name>A0A8K1CLA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptide chain release factor N(5)-glutamine methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLA4"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050320">
        <property type="entry name" value="N5-glutamine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895">
        <property type="entry name" value="HEMK METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895:SF74">
        <property type="entry name" value="MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Release factor glutamine methyltransferase N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="145"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37938" checksum="507B9AAB74153FC9" modified="2022-08-03" version="1">MEMRLRNALVRRVCARNRCVSERFGRRFHGQSVQETLAQVRERLQRSGVHGSDAKALIAHALTPKLASSNDVFLHSDRLLTAQEGEELTAFLDRRCSGEPLAYVLGYKEFWSLPFQVNRDTLIPRSDSEVLIEAVASLYPRDAPLKVLDLGAGTGCLLLSTLSEFPRATGVGVDICPNALQVASANAAALLDDSNRATFVRFDMADLPKDDTALVNNHLIQRFDVILCNPPYIPQSELPLVAPDVFAYEPHSALFSEVPQGQVSSPEDPKKDLGLRFYEYLAASVSRLLRNDGAFQGSVVLEIGSERQAHAVRDLFPPNVVSFDRFLMDAAGKYRGVVFRSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLI7</accession>
    <name>A0A8K1CLI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deubiquitinating enzyme MINDY-3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011392</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MINDY deubiquitinase family. FAM188 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLI7"/>
    <dbReference type="OrthoDB" id="9981542at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025257">
        <property type="entry name" value="MINDY-3/4_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039785">
        <property type="entry name" value="MINY3/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473:SF8">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13898">
        <property type="entry name" value="MINDY-3_4_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01174">
        <property type="entry name" value="DUF4205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Deubiquitinating enzyme MINDY-3/4 conserved" evidence="7">
        <location>
            <begin position="13"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="516" mass="57102" checksum="3357114BBCCA0010" modified="2022-08-03" version="1">MPMLSTETTHALRRLLWARHQPQQDIDRWYQQGFVFQSPTSRFPLGLVQGHGGPCGVLAAVQAEVVRLYLFPERETLTTDARMTKLTKEMSEDAQYEWLARALVSLLYQCASTRADGVRDIRIVMNEDSTASDTKACNEQVYVEEVVSVSSDSDRGLIDCIKSQKAGWQSADGVVLFMFSVLRSRGIDAIRSDMDDQDGNLTGQFGHCSQELVNLLLTGVASSNVFDGAVPMGDTGLMLRGVEARPRLGYLTELEALRYCQVGYFYKCPMAPVWVIGSTSHFSVCFGLDDKLSEVSASQMLMQRIQRVFKSFDPMEGGFLDIGSLVDSLKQLGVSNEILSNEYWMGQLFSRLEVSGAGIVLWDDYWKIVSVLLHTGDLELALSGNFSAMSSGSRPKSDEEIARALQAQFDAEFGAGSATQTTEDISAPDEEEFDVCYYNGLAKRPDSTRQNIPGDPQLARAHIKCSRTEEFIGQSIPTELSSVGSSQGSTTFDDILKTKWPQAHIRWEGESVPSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLR6</accession>
    <name>A0A8K1CLR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ARMC9 CTLH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Early endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Late endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR91 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLR6"/>
    <dbReference type="OrthoDB" id="193023at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141039">
        <property type="term" value="F:phosphatidylinositol 3-kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051898">
        <property type="term" value="P:negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056327">
        <property type="entry name" value="ARMC9_CTLH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039724">
        <property type="entry name" value="WDR91"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23138">
        <property type="entry name" value="CTLH_Armc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARMC9 CTLH-like" evidence="6">
        <location>
            <begin position="52"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="690" mass="77297" checksum="F3F6F9DF7F22F251" modified="2022-08-03" version="1">METHTPAQLLPHVDELVMEYLLFRGFTKSFQVFVSERKRDRAKGFDVEQLISQLLAYVQNYQIESILETWKFLSARFFNHVDSAYAATVQQLEDAWLRLYVVNAIKTGHREKAVEFFTLMISFPHFAQEDGDSWSRWFIAPYIQNPEQDPYFRHFFAKEWLESFVTSFRNFLSVIFHNLPLPKLLAFQITRLQEPSLSLRLKVSQAECSRLRLQNLQATERIRKLEDTGRQLYEMVRSMVQHSFMDHFMPSETPSEQSSPTHSPDKEMSLKTMAMLADRLKALDVTFAQGNSHQSGSEDPAPLLDPLRMKLHPMAPSADSDRGTRASASSSSVASTSPTTKKSRHAVRVTEVPIRCEDDETSLSSCAFTGDGRSMVITGSGHDHMLVVGNDVSQNCELQAKIDIAGQLVDADWIKDNRGLVFALDDGFLGYWDRLTGKTSANLASSSMETFSPGLLSCARQRNIGALALKMASSNEPDVARVQFFSTQSKTIEFRSTIDIEASEIVSMDWAHDGSLLVAGCVGGTVCLCSPTSDRITWNVSGDPQGRPTVSFAPSGESILTADVTISGTITEWFVDEKIRSFSIDQPRKKFEYRIPEDLLRSLEEPHVSCIQFNPVADRFVIAMSSNAGVNGQSLLLVFKSGDPHPERAPIHLEGCLKALVWRDDVHVLASVSRGEKAALYRFGFGTESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMI5</accession>
    <name>A0A8K1CMI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMI5"/>
    <dbReference type="OrthoDB" id="158739at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47355" checksum="8DA37741E38AE131" modified="2022-08-03" version="1">MSLSTQGYTIYLVVDEVQILYKDRTSSPRRKSTVFWELVKLVRNDAASTIRILMFGAYGSDPQYTQSMTPVDFSADMVLGIKHLNFRREEIEEYVEKWFVGIRCLQGTMKTFCDCLQFLTGGHVGLCAVAIGVLNTVYFSRVGCGGVTPFAYDWICMLEQGSLYREKDHALFDALILTCAVKVLTTLEMEDLDGLERLFYGVENHLDAQLLDECIRKGILIGCEGRVEFSSPVMWRYFVKMRVGHVDRALHGPNTLQEMIARVVRAIDYDSIRKTLGRTLSNDIPLERAWQMEFYKASYRCTPSTCVTSADVGALFGSTGFIDFTVECGDNFWGIELLREGSALDEHIGRFAPGGSYSLLQLSDYCLVDFRRVSSMEDTARATTIQDLNRCEKLYVVCYDRKLAHVSVLNSQSVWNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNE4</accession>
    <name>A0A8K1CNE4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003858</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNE4"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001953">
        <property type="entry name" value="PRK00733.2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="601"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="794" mass="83620" checksum="435540EBAA2E82A9" modified="2022-08-03" version="1">MRDIEYGDGGGYGDFGLPSGANKAAHAYARKIDVQKPFIAISALGAVFLLFSSDFRPIFLVLTFCGYGALFSFYLSHWVLSKDDGTPEMREVSNPIREGAEGFLRIQYTAISRIAVGIAGLIFFSYALRPSSALASGVETLGNMTLGVLGSLSFVIGAVCSAAAGYISMWVSAQSNIRVTSAARRSYGEALLICFRGGAFSAVLDITLCVAGVSILYVVLYVMFGSYVALTDIPMLMVGYGFGASFVALFMQLGGGIYTKAADVGADLVGKVEVGIPEDDPRNPAVIADLVGDMVGDCVGSSADVFESVAAEIIGAMILGGTLAKEAKLDYPVAFVFFPVVVHAFDIVVSSIGILLVKSPSDVDASRANHNPMGTLQTGYNASLGLALAAFALTTRWLLYSERAPGAWFHFFLCGVVGMITAFVFVKSTQYYTDYAYYPVRSIAKASTTGHGTNIITGVAVGMKSTVVPTVMVSIAVISAYHLGASSGIGGPNNRHAGLFGTAVATMGMLSSAVFVLAMNNYGPIADNAGGIAEMSHQPDYVRDATDKLDAAGNVTKAITKGYSIGSAALACFVLFGAFMDEFSEFAGRPFKTVDIATVEVLVGGLLGTMMVFFFTGLAVAAVGDTAAEVVNEVRRQFQLYPGIMEYKEKPDYRTCVALVTQAALKQMRFPGLLAVMLPVTIGLVFRVIGEYQGKPLLGAEVLAGYLMFGTVTGIMMALFLDNVGGAWDNAKKYVELGNFGGKGSEAHKAAVTGDTVGDPFKDTAGPALHVVIKLLSTTVLVFGPLFVSRVANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNJ1</accession>
    <name>A0A8K1CNJ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNJ1"/>
    <dbReference type="OrthoDB" id="10045021at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="47389" checksum="03CCAFE2A0990055" modified="2022-08-03" version="1">MAFDASLAVLMAAKYCKQYPLFRWREEVLPEIGRREEKLCCRVDLTNLLQDQGQEMLMTLFPAQLSFVDFQKENTLYKLKALMVTMKHPYILPVVDIYYSKGKKGVLVVQPFIATGSLKDRINRSDPSRPYKEKYRLYHASPLEFHEVARFGRQILEALNALRSKGVVCDHLSTGNIVIDQGNARIADIYIPLLAIDRHKDSRELTVSLEARVDVDVLLFGRVLYEMATGMELTTPIPADDVLELLPPEIADVLDLIFYQSKPATDDREAILSIDDESASIISDGSGSSNGDKSIVDTLLECALFTGATDVPPIKTLFSGFRFDSGMKSTIRHSMRINASRNHAYVVQYKEKEALIRARQRAERRVHDEREKNEKRAQQVAVARVQSSTQNKAPSSRRKTYRANSFRSPLDRQPSAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNL5</accession>
    <name>A0A8K1CNL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNL5"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="41758" checksum="15BF5CE4EE7B98FB" modified="2022-08-03" version="1">MSKPRILVLGGAGMIGRNFVQYCVENDLCSYIRVADKTMPEIAYFNPTHKSAFQDERVKFVQADLTRDAHLERAFHPESGPYDFVYNLAGETKCGLSEAVYASKCRDLSIKCAKYAAERAVDLGIRRYVEVSTSFVYKSQSKQPANETAELSPWTVQAKFKLEAEEAIRSLRELDTVIVRPATVYGSADFMGLMPRVVCAAAYVKLEEKMKLLWDAEMRVNTVHVNDVSRALWHLSVNGKRGEVYNLADKNDTNQGKINEILEGLFNIKTGFIGKLVSNLARVRLADVVDEANDKHMEPWSELCQEHTINNTPLSPYIDKELLQHNHLYVDGSKIEGTGFTYQYPMLQASELRKVVEEFITQGVFPPVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNZ5</accession>
    <name>A0A8K1CNZ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNZ5"/>
    <dbReference type="OrthoDB" id="21589at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039751">
        <property type="entry name" value="HERPUD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943:SF27">
        <property type="entry name" value="HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943">
        <property type="entry name" value="HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="614" mass="67063" checksum="54C7CA80FAB9E41A" modified="2022-08-03" version="1">MTSTTADRDVRILIKNVYAPSEPQTFVLADSLTIRTVKEMLQQAVTGNPEPKHQKLIFGGKICDDEQPLRRILSGQTQAQDGSEDMTYVFHLMVTSVVPRSRPSTPSARAHSEPPTPRVVPSTVEPPRAVTPPANVEAAQTPTSAFTFPPVQTSTHAAAPAANPMAQQHQQQFYMQSMLMHQQAMILSQIQYLQQLQAHYAAHPPQQTPAQPAQPAAHAPFGQFAYGMGMHHPAMFGHANHIPGHPAAPAAAAAATTPGTNPVDAQQRPVGPIAQAFREIWPLCDIRLAMKMAFMLFIIGQDTPQDRLIVLALMSFGAYLHITGILAKVYEVYQRLNGQAEAAPAENANGRGEAAQNNPNGAQNAQSGRQGLASLTRHLRIAADRGFLQDVRYFFTGFVLSLAPAWHPQPMNGDGENAALVGQDGNALTSVDAVSVDIEDVVALRDAVKDKYKDSHLAGIAPSDLTVFAVTQEGKQRLEEDSPIESYGATKKDVLIVQVPQRAVAMDVRGNLNRVQVQFATGELNHLLNKDPGKLVWIRYLLGLVYYYIYTERLERTEHVCSLVEGLDLSTDTTGAVREMSQDRSLSPGEALALPRYLLKVQYTSDFDVLKMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP21</accession>
    <name>A0A8K1CP21_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP21"/>
    <dbReference type="OrthoDB" id="165008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="524" mass="59190" checksum="2A32CBB570052F1F" modified="2022-08-03" version="1">MELIAPINDCTYVLYDDAGSSGRYFYLARERANPDRVFLVVVSLSMQQYTLPAQAETGPAGVGMVQVTYDMREASVTNYYVVAKGFPVEEMGYRVYEYLNTTPDGQWTLRSIPSTKSEFAMVLITSIREGFYIKAPSEQSNINNQVWLAPSTPSEAVGIWHFVYTPVLRDSWAWVHGVQFIIGIRLLGNLVILCLTAYNNLRARKLWIGAAFVSISTSQVLNVVLVLVSWFMNEYWSLHEYSVTVGYAVIGLPDRLIHDTVMHADLLTLYFGACGLIGSVFRERIDPLLAMALFEIGYDRQTRINLLINSHHLHAKIQAFAYNFYMRGVLAPLNGQDKISPMVVQASHNMGKRDYDYVAVCLFPVFLNLVWVVAYAILRKIYRRIFPPKVLIQQNTTGTARSGNEESILAQKRVHTLFELATGAELENRYGLVSDYDTCIFIRGTKFASADGIYSNGFVIANKKYLVQASDIWTIVAMKLLRSRFTNVYVYEVNGTTVQPTALLVYPHTLTVRDLLNLNVSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ69</accession>
    <name>A0A8K1CQ69_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ69"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="653" mass="73296" checksum="08116E47F44D3F09" modified="2022-08-03" version="1">MVRKEPSTHVYPEFEALRMPIGPFNLQPSDVREIREAMELVSVLACVDPEAWAQTALVYTPYSNAWYSDRTLVSLATPRFQLSFEGSISILIDGGSYTYMDYRPLLKEVFEPLRLGRRSAAYQSTLKQLLALVEDEETLQRCQELQIPIKFSGLFFDPPTCSSFQTALELYAPRSSNSLALGCPMTLEDVALELVNPRGILLQAAELAQSIAASTLPLRSLRLRVNRATSSLVHAGALLHPSVTHVDIDCHLANDPDVIRTFTTLAVTKTVESVHITPSYFRTRIRNAVLRWMAFAFFNRCAVSPVHTLELNANELTLGEVAAMKQVIKAKNPLQVLLQSNAPSCQAAALVKDLEIDVLDLDAPVLLKKGTTIWVLRNHQRQHMVDALVPGCGIQRLDRKLITTSTAVGDRTRITRLDIVFRQSAPLNLDGFFAFLDIIGAQLTSLLVSIQGNECCMSTEEVVQILRKCRHLEHLGLSNFRLESLDMFVDAYESQDCHIRVLQLRKCTITTPTGFDHFMNTLVDSPSRMARRLRQLEIDFSGTAAFLSPPATVADMLRKNYYLEEVFITLPRDRSHFFDAMLKELPEIRLHVPEKSFPMRSKLAFLSVSHASTTPRATEIRCSMERMDRAILAEIFVFAAPPATRTVCVDVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ93</accession>
    <name>A0A8K1CQ93_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_004163</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000029">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="13">
        <location>
            <begin position="1397"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="2202"/>
            <end position="2517"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="14">
        <location>
            <begin position="2618"/>
            <end position="2650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="928"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2505"/>
            <end position="2549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="2512"/>
            <end position="2522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="2530"/>
            <end position="2540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW66398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2650" mass="297494" checksum="B5465F3DE25057A8" modified="2022-08-03" version="1">MMWSTSMGTVPFEGEEVEHDEANHAAGFMDSLGRFLPGLRSQSGATRYRTARDLRGFIESESRDLSHALYMKWVAGISAKLMDMCNSNETLERMGGIAAMDELVELFITERNDQTIIEFAHSLTKVFEKIPAADTPTLRVASKALGHIVSTGGTSLIEFVEDYHVKPALEWLKNETFHVRRQAAVMILKELSINAPSTSFRHMDRYFDFIWSAFWDSRVVVRVSASESLQTCFSLIQQRESNRKSAWYSRALEEAENAIRRGVADATHGALLIINELLRNTGDFMHPHYIKVCQLVFQLQDHKNSAVRAAVINLFPRLAKFNTSVFLEKCYRRCMLHLLEVLHSATTTTRADGLLSIGKLSLAIGPALSRDEQALPAIMSGIKIGLQVRKKEFDTHKEALACLRMLAESVGPALVRVDLEAMVTQLFQNDLDASLVETLTTIVKKIPAQKQYVQMKLFERLNLILSAARQGESSNAPQSRSRTKTSSSSVKSGMLSLFSSALERSNLTSSADPTSAAVMSVDAATAIAMQSLALETLANFDFQGNRHIPVVEFVHETVVKFLDHDEAQIRRSAAITCCKLLLPPGEERGMMTSEEFGPSVTAVLERLLAVGIADREGSIRLQVLRSLDARFDPLLAENDNLRCLFIALNDEHFEIRQTAMSTLGRLTHHNPSVVMPSLRQTLVQLLAELEFSGDSRGKEEGALLIGCLLRSASQLAKPYVLPILQALMKNLREDSARARSRSNISVSRAILATLGDLAEVGAEELIPYLNQLLPEIIDQMRDSNNPQILQVAIKTLGQLVSSTGDVIRPYHEYPELLDLLCQALQKSGDAFESLRIEAGRTLGILGALDPYNLRLFHLQKQGKLTTMPTRELRLALPGADPTNPTADDLANPSKSSTGVAIGFGSAALSTLPGEDEGASLDLLLSETRTRRETKKDQQTSNKLSVTLEPPPEDILPSMIEDSSQYFPSVVVNALIRILLEPRNSAHYQGTFVAIMYICKSQRRRIEPHLSKIIPAFLYTMERVNHSLRKFLFEQLCDLVQIVEEQIQSHLDHVAMMSIINSYWDEHLEEVLNLVKRLATSLGEKFRVYLPDLVPELLRVIRSERDSASRPRTLLVLKTTVSLGRLLDGYLHLIIPALVALIQSDADLNARKQGLGSLGSLVKKLNVSVFASKIIHMLARVIGSQPELVYLAMDCLCCMVYTMGNDYAIFVPVISQVLGRQTTRSHDIFDRYDLLVSKILKHQPLPVASWATDPLRGRAEGATERTDSSNNGDEAKALPCDQKNLMNAWEASQRSTKEDWTEWMRAFSVELLRESPSPVLRACKELASVYQPLARELFNASFISVWPHLGTQTQDNLIRSLEAAFHSPNLPAEILQTLLNLAEFMEHDDQSLPIDIRHLGSLAEKCHSFAKALHYKELEFNTNPTADGIQALISINSKLNQPEAAHGILKYALGRLSGVEVKASWHEKILKWDDALATHDRVLKDDPSNIEAIFGKMRCLYAIGEWRKLNDHVQDTWSKIYGDGHGTLAIEGEETGLLDAPPALKKELCSSGARVAFMLQNWDAIPKYINTDMDENESHMFQAVVAIRRMELDEAMNSINQCRKVTDTMLRSVVGESYSRAYMPSIVNLQILTELEEVVAYLRTFASNNNGELTLLSTPTSRRKQSISSLNFVSTASSSKYEHEKQAALAKLQSTWTKRMLGVERNIQVWQNLMLVRSLVFDAREDVDIWLKYARLCRKSGHLNLAASALYRVGAQPFIRSMQKDPRAPIPLNLGNTGSSFTISGGLSTSSLNFSDGATPDPRVALSYLQHLWYENREDIALKQINHFIEALERHQGDESNEELIKLRVQVYIQLGEWQMSLPEPRKQGDGSFDQVIGYLETATKLDPTNHRAWHEWALMNFRAMESTVKDQADSNQVKRYASSAIQGFFRSIAFGYKRFDVTKDVLRLLTLWFAHGHRPDVHTAMVTGFQDVSIDTWLDVIPQLIARIDSPNAKMNELLHELLSRIGFAHPQALIYPITVASKAMNVNRKTAAEGILAAVRRHSPKLVNEADMVSRELIRVAILWNELWYGALEEASKHYFNNRDPQAMIAELAPLHEQMEQIGTEETPTLREVAFYQAFARDLKYAKEWTDLYEETQNVDDLNQAWDIYYNVFSRIRKQLSNLSTLELANVGPKLLSVRGLSLAVPGTYKAGAPIVRIQSFDTKITVLTSKQRPRKVTINGGDGKSYPFLLKGHEDLRQDERVMQLFGVINTLLANDNDTSKRNLAIERYSVLPLSHTSGLIGWVPNCDTLHLLIRDYREARKIQLNVEHRLMVQMAPDYDKLPLMQKVEAFKYALGETTGQDLSRVLWLKSQDSEVWLDRRRNYTRSLAVMSMAGYILGLGDRHPSNLMLDRLSGKMVHIDFGDCFEVAMERDKYPEKIPFRLTRMLTQAMEVSGIEGNFRYTCEASMRVLRENRDSLMAVLEAFVYDPLINWRLLKKDAVPSHARGAEGDDVVNAAADRNGVAAGANGTTTQESETNGTNDDDRSSVKSTPSVSNTPPRRRHSSTEAMFAFNMDGLDTGSLARNSIQEAQREYDTKNIGSSVISTELPQLNEKALSVVDRVKKKLAGRDFDDGEKVLSVDEQVDRLIIQATSHENLCQLYYGWCPFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR68</accession>
    <name>A0A8K1CR68_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR68"/>
    <dbReference type="OrthoDB" id="123866at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="500" mass="54397" checksum="B97182EF1A316C8A" modified="2022-08-03" version="1">MTPVAGLESSPRRVYIIDDLLGAILLLAAGALLVLLDLTRRQLCAVYQLAFVLFMACSLFVIGGLIDVHLSNDQLQLALYSSYVSRALTTSYVYAPVFLGLSITALVLYNFSVCTCDCCCVVGAKSSGHQRCFTQRIRAHVSLYLTCFVGLYVAVGMRLNVRLRESAIHPVGGTLHWMMLRSPFYLSMIHMASLALVLLKIFLQHAERSSAHTSYHNFQETLTQSSVSMSPLAPPPAPMTASAVVEELMRPPPLHKNLPLASRRSNELKTTLTRSPHHVTKPESKAIGVGAKSSASHRVPTPNGSGRRRSEENQFDGDVSALISSDSESDDEVLQPKFSTTRRTSPAPSLGRRPSDGSSSSAVSVYTASPPPSPARSSSSTSASSTSFSTSSRPRAALPSSRPAHSRSRLSSNGSSSSTTVFSDSDEMLLVSPEQDPAQYHNDQPVTLRRRLTARRVLSPPLTTMVEPTTEWIECFDDTSGSAYYYNTRTGESRWKEGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSD1</accession>
    <name>A0A8K1CSD1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rab proteins geranylgeranyltransferase component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSD1"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="686"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="79732" checksum="85626270A2E517B6" modified="2022-08-03" version="1">MALYHVTNVYIEEESRRNGLEGDGGRLRGLTALEKLTMDATLLETEYDAVVVGTGMAEAILAGALARVGKKVLHLDQNDYYGSNYASFPLEQFLRWTRNEDITPRRFDEDDDAPKKPLEASAPSETSTATRVLPMKSSFQCHLVEEGFSEHVSEELQQAMKKKSSQFSIDVNPRLVLSSEEIVQILITSGVGRYLEFAAIERTYVHFQDAKDKDNTTVDTVWDVPCSKKDVFSSKLLGMVEKRMLMKFLQFVADYGETHIRGDDVKSKNERELALGRSLKRPQNKANQVDAVDSAVLEFLDRPFQELLSKHFKLSTKLQEVVVYCVALASFPVDAPSDSAHAQVQQMTAREGLAAVYRFVASIGRFTGNAFLVPLYGVSEITQSFCRLCAVYGGIYVLRAPIDGFVVDEETQALCGIRCTDGAVIKAKNVITNASYLASFEKEHTPVAQVLRGVFVLDRSLRLDMNRFMVVIPPRDAGLDNPFAIQIIQLDRGAYVCPEGQFLVQITTPLPAQWQSNKEKQQALMDAVIKRLVQSAMAQRNATKKTQSADETEGEEKAQDDLPEEWASWIVWKAVFAMDHHLAHHTASPSDAGEESAAARPEGLPANLWVTETAFGGNKSANPLEIHLESASLNARVIFEQLCPNEEFLPKSASAEQAEQEEEDEDDVVLQAAQKLAKQADLIATSAVETAGEQSEAEPESVEQQGETSQPIAPESAVKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSX1</accession>
    <name>A0A8K1CSX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSX1"/>
    <dbReference type="OrthoDB" id="65213at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="2">
        <location>
            <begin position="17"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="71" mass="7702" checksum="BC785A92E05E2196" modified="2022-08-03" version="1">MGAEASKVATTEAVNPCATEMETYIKCVESKNAESGGLRDGDECEKESEAYRECRRIAKELKKATAAAQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT43</accession>
    <name>A0A8K1CT43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT43"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938:SF35">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938">
        <property type="entry name" value="RESPIRATORY COMPLEX I CHAPERONE (CIA84), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="147"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="34696" checksum="BC2041A2D10F3F4B" modified="2022-08-03" version="1">MGVVTVRFMRASLLRRRDVRLLHAARQSTALRSSYPTVAMALQERTGTLRFASSSPAVKPDDASVLALLERSLAERQPQQALSYFNRLKTPPNQLLSQKLAMLLAKRGDRVQTDRAVEILRGVYMLPALKPDDYTKLASIYVVDACLRHNRLDQALEIYEEAFNVGVTLDLPAYDAMIQALVDADRVDDATELLHEISADNDVSPTERSYLPLLTALIERQDYHTATVLLQKGRARDVEFTSETFYPLVELAEADDDAPDSLVSFLSYVENVWDEAKLLDHLAEADDDDDEDLDFDHDEEDDENPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTC6</accession>
    <name>A0A8K1CTC6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTC6"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452426" evidence="10">
        <location>
            <begin position="29"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="40073" checksum="C6E477CEB537B12A" modified="2022-08-03" version="1">MTALTVYMRVALALCALLACWGASPVEGKKKTDYLKGSEKIAALNGRVRDGVVKFTTETYQQFVVRPDRPYHLFLLYTAMGDKYSCDVCKQIDPEFHTLAESYVSAKQVKVDTRDGLDVYYGIVDFDENQQVFGLHGFTSAPHIGYIGPDRTEDTGKRAPSKVEIPTHDMYNVYQDGKQAESIIKFVKQKTGFEFEIQRSKAFLYAVVGAVLSVFLISVKIILSNLNLVLDKLRRRRLWMTVSLLFYGLSVSGMVYCIIREPPAYTTERGGKIKFFHPAGRSQFVVEGLIVGAYDVMAAGFVILLSQWAVYLKNPVLRYSALMICMSGFLFMYRQMISAYMFKNRWYTGWMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTP4</accession>
    <name>A0A8K1CTP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTP4"/>
    <dbReference type="OrthoDB" id="347435at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="37727" checksum="C8B8753CA0F25450" modified="2022-08-03" version="1">MRASWTALRAQLDAVVRRQRHVVAGDSEDVVQEKIERYFWPLYKWVEDVIEQTRQDTPAAKRCVCIGLSCVQGGGKTTMTRLLKEMFDSTGKKCAIVSLDDVYLTRAEQVALAEANPTNPLLQHRGNPGTQDMPLLMQFISECKTSSGEIASPRFDKSLHGGRGDRLPVEKWERVKGPLDVLLVEGWCMGFRALESTDGLNENLVPVNDALRDYEELYKALDALVVIRVDSLQWVYKWREEQEQHLREAQKPALSSDQVRDFVDRFMPAYETYLPDLYAAPSNASPSTPTPATQHAPSNLERIPRMVLRIDAARRPSLAHPPEILNTPTKEITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV65</accession>
    <name>A0A8K1CV65_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small ribosomal subunit protein uS4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001431</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV65"/>
    <dbReference type="OrthoDB" id="1697570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000021">
        <property type="entry name" value="40S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="9">
        <location>
            <begin position="52"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW69275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="27342" checksum="EF421C37643417C2" modified="2022-08-03" version="1">MDAGGWLVGRESCKARQAIAIAGILWFSPPVLTLAELKNAEKAKMPKVSRHRNYRKTYRTPSRPFEKERLDQELKLLGEYGLRCKREIWRVQFMLSKLRKAARELLTLDAKDPKRLFEGAALLRRLQRLGLLSEEEAELDYVLRLNVQKLLERRLQTKVFKQGLAKSVHHARVLIKQRHIRVGKQLVDVPSFLVRLDSEKHIDFSVSSPYGQGRPGRVARRRAAQRAAAANGGDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV82</accession>
    <name>A0A8K1CV82_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV82"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="139" mass="15505" checksum="80FDE0A99DE96516" modified="2022-08-03" version="1">MYNNSQYPPQGYPPPQQSGYPPYPPQGYPPQPGYPPQQQSYPPPQGYVPQPGAYPAPYPYPAPVQPPPQAYYAAQGRVLFAQATGGGYVAPPGYVVQQPGVVYQQPAYVAYPGVMYGPKIKYKHRKYKGHKYKGFKFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW47</accession>
    <name>A0A8K1CW47_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
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            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW47"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="184" mass="20001" checksum="D307C552BA38D213" modified="2022-08-03" version="1">MNDAAIAAAPTTPDSTPAPASQAQRLELLQEQQTKLSKEQKLAPVRKLEEQKKRQAEVTRATSECTKKQRQAYLDQQKAMLPQHQHKLRRQEAAAAPASVGQQPGAMLSSAPSTLLSTSLTGTTPTATITATGATASTTPSLTSAQYHTFKLSEQLKQRLTAQPAKLREQHQRLIMAQPRARPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAM7</accession>
    <name>A0A8K1FAM7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
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            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="165606at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="354"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="648" mass="74174" checksum="3D53EA4CEC2EFAC9" modified="2022-08-03" version="1">MSSPSSSPALSMASTQSPARGLKRPLADSATGEANKRRMSAGSPARSSPGMEDESLRISNEMLRSENETLKDKNAALDRQLTQQKQRIRNLEEDLTRIYRRQKREAETRQQEHTKALDAVRQQLEVVTMQLEDRPAFDPKTSVMTLTPETRDQMDAFVAMCTDWQHQLTTMSTQLTEKVAKMEQDEVEAVVKDLMQKVDQDHEKQALAALQTRLDAQYNLMLQREHEMLAFVAKIKAEREEAECFETMERSVLEDRVKELEARLTGAMEQEMAEREQVTSLRKELERMHTENHVLPKADWLKRLSDEEHWKEQLDSLSVQCEAQSVQLTLLREDLAGLQTEHELVVTELNEYKEGDANARARQLQARIDELKLKLEEATMNAVEQAAEVAENAKQEAQEQIVALQGEIEGLQNRIEVLTMNVSAKAKVIEDLQAEKRELTEQVALKTGEQEEMTRQVGKLNEQLDEQCAHVVNLSKEVRDLEVAKASLLQQHSAKKSKQTKLETERGEREAKLEEQLAEMQRKHQALAQEKEEWLLTQAELQVQLQAQSDDSVSVSDPSAMADAEKRISKLVEEKHLIQEFLRCYFEKAESKCRELIQQVASLETQQETHRQQARDSCQLLRMCTQVETCDHTVRASLLDVVTVLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBP0</accession>
    <name>A0A8K1FBP0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="108005at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="64174" checksum="938DB39F94D7DE82" modified="2022-08-03" version="1">MPATSPPKGLLHALLQESRDRVAYVRAGQPLTELLESGLCGAGGPGFPAIPVQSSLAKHPHKHHATRLSSEQTKKQPLPLTSYAQYDDYMGAKPTDHPIAHLNTRRRGVTLRSKQLKKLLSTSDIDLDAAADARASGKAKLTSAFAALRSHHAFFNIKELPPVEETYQDIKNPHMAFLEFKKDALPPVASTPRARHVKITELNAPTHQPLRFGDQICLISMASDLPLAIGRDGRTLAVANAVVGQHVIFTITDFRHPTRHDDILVGEDFWLRVDETQLNLPPPDEVMALVADTSYFLGCPGYFEAASPSRHRRQVVSSASAAAKYSHVTNEDEQDAHDRRTFKLVTMKAMRPSKEVYGDDAATREYTLESNPSVVLLAKWRFVMAKVPSQKSENTRLVLNCASVSLQLSTFTLEYDGEVKRGVLRENGEDERRLHLPAAQWQVRLVRRPEYETEDPGSLRRDGSPATRVEQQRMDEKASLEWIARHHEQLAERARRRKENQVLVKQSRHEYDRVVEQSDAQLVQIQRAKAEHYTEYCQNRSIHGQSHHQHKKISSRLTKNTEITLLPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBV8</accession>
    <name>A0A8K1FBV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBV8"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="169"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="525" mass="58466" checksum="D45F5F3177458312" modified="2022-08-03" version="1">MEKYIKSHWEAHRAPRVECLVYESGYCSEHYRVNLSVEGVELHANRVDAHGGIFGHKKKRESVDLIPWMDVLGASLVTEHDSSMPSDPVDFVINACVPKYRDKRSRRILHPSTSTEKASAKEFHDRVLVQWKFRSQGSDGEKLVPYLVSLIQFLADPRTLATHPATFPLPRRKYLVYINPVGGAGKAKQIYAADVAPLFQCSNIECEVVVTQHQAHATEHIGTVPLNTYDCVVAVGGDGLLSEIVQGIMKRDDWKRMIRQPLGIIPGGSGNALAASLLARSKEKTTALNAAYALSKGTAQDLDMATILNDHQEVMYSFLSLSWAFIADVDFGSERFRMFGGFRFTIAIVSKLLSSLRPLNGKIRYLCSENDSSPPTKYHERPHGYDGEVAPVFDCYAARPDQKEPHVQGEWKELNGPFHLFWGMNVTHGASDAEVAPSASMNDGYYHLVCIQSPFSRLDLLRVMLGLEDGSHVNHDEVHVIRTRAFTLHAEDSSDLIGVDGELFNGPHIQVEVHRALGRIVCLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC23</accession>
    <name>A0A8K1FC23_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC23"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="302"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="610"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="722" mass="80541" checksum="168DCE3A5A1F7735" modified="2022-08-03" version="1">MRRSLSSHSTAQPLVQGFRALQADPDTLSVEDDVLDDDDYDDDEIDLDAYEAYLDEIQRKTEQRSSQRTREMRPYPMEAPQFYMVTANNPALPVDQDELQIPLPSTATSRPSTRPTRPMSARPRLDGGSKASSDMKAQLPRAPQTARPASSSAGVRRKRQEDAVSARIRAVYSDVGRRSSSSSAPSASATSSVTASSVLQSRLRIFQQAELHDEYYKLVDVVTDLRAVVQHEQAKRLKAIARVRRLEEIVAMKDKKIESMLQSTGVAMTLGQDVSTASYLQRELAHKERQHHVLTSKLRHRLAQQSQLIVAYEDAMQRLRASVKSTTLMELEEERAQLEMERQHLQEVIASQQMEMSRLGQQLQDLNGREAQWDRHVAEIQRDKQRTTLEKRKLEQDMSFLRAQVDQLQHQLSLEQRKRTYDHEVASSPRWNHQPSIRLSDSTSTLAETLVAIKSVAKPAVKTVGSSPKVMKTDHNVVSSKKSSARETSAKDGAEMVAPAPILTQTEVEEKQADENSVRQVRWQDDEKKMSPTEAKTISVNETNESEEPSPPHSMDSANEVTREELSTRAPDEDVTEREATKVDEKPVDEQGAEHETPVNELREKDPAQSCSSELEGSSTNSSYSSSTESDSSLTESSSNSNSSSASCSNSSSSASLSASEIDAAAVAMTQELRALGLLENGRRTTSEWSLPDATDGEEQEHDVDAELEDDTFMYELDFTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDF7</accession>
    <name>A0A8K1FDF7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDF7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="20636" checksum="FC83036906F8C26F" modified="2022-08-03" version="1">MPTSSTAEAREAFLDDRLRHLKTVMETFDWNASSPLAMRLQMNKLLRAAQHVEIGFQLKEERKEARAPYSRALVDGLPHEIQLKRLMEAYDKLKSEQEALCLALEEKAIETRLSMDTALNRLVPKRAKIRHDKPKQKPADPDLMEQYITLQQKYSRMKERYATVKQKLEAERKKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDT9</accession>
    <name>A0A8K1FDT9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDT9"/>
    <dbReference type="OrthoDB" id="129274at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="72651" checksum="052DFE73D0C69A50" modified="2022-08-03" version="1">MTLEISYVVYGDHNADVLHAQVPSYYKIIDLHATIILANTQRFQCDPIDLTLYRATDASGGWLRNDPDLSRVLLQGDASGQYPVLPMYMDLVDVFGGEFTAEADTVQILVRPPDFLLSTIPQPAVWEDIAKSSTAFGSLPTEGEFLRLFEWSDDDCGTAKDMSAIQSTMGEDLVPAQLYVRKEMLCVLAIFKAKYGNVFDFSRITSQFVVMGSPGVGKSCLLALVCLYLAAKHRRPIIWRLETSIGTVVRLLYRHFYYEWVDPYGDVYTSIVRKTLLYSPWRFLDGVSLTDIRRHNWLYEFSLLTTHPSDEVVPRSWAPPCLLPYWQKRDLITLGRRLKWTTDEAEARYFVSGGSVWAFLANRVQHEDILTSVKFDPDSYSGSDTLCMYGVDDINDLSAYEDTDRRTCDVTSRFKMLTRATHLLPTHLRSLLVFVEDLKKSPDGSTDDILFSSSFLLAVQRRRLVRVHCSACKSYTIAADAWRSSERVMEWNDRANSSTCNALLRQEFRVGRTLDECERVMAQWATEPNKLGYWIPQTTRAGVPDIVLKWTTQDSTTEFFMIQLIVEPEKCALDYDVVWRLAKPFVDKALRINWMVVAPYETETSFLSGFAPNQGVTKHLPVYVGCVDDLSCDDHAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDU7</accession>
    <name>A0A8K1FDU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="255"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1317"/>
            <end position="1567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1576" mass="176375" checksum="6BB9B4548CF3C6D4" modified="2022-08-03" version="1">MTSNPEVDLFEAAFRGDVASVKSLLEGGVDVNAVNKVYETALHLASANGHVKAVEVLLDQGADVFDRKNRNRMTALHYAAINGHVRVVKQLLATSSDNVDVENNIGQTALHLAVVNKNADVVRALLEDGKADVDASSVSFKETQDNNQVQAKQTALHVASETGQRRMVELLLQYGANVNKWDENGSTALHLACANNHASVVKVILKTAVVDVNAPARKNPFLTPLQKACSECHDDVVWALLNDRRVQLNVAYNKDGWTPLHLAVSNRKQNIVNMLLTARGVNLNATGEWRKTGQIPDEPEYWVTVKRPITPLHLAVQCNYAEMVDAIVGTKGVDVNAEVEEHYVEYYQSQWEEIPDINRHPSPGTALHMAVEDSKTAVVEALLRAECVDVNAVHAEGWTALLRAAEKGSDPIVSALLIREDIDATVANQNGWTSLHYASANGNLKVVNALLRKKDAKCLVDARDSEGKTPLHRASECFDQSPALVVKALLAVMGDKVNDPDKEGNTALHLASLRGNVDVVRELIAMDEMLVNAQNGKGETALHLAPTKEIAEQLINRADLGISDTGGNTPLHFFSWRHQSAIVALSVTFECDVNARNKDGETPLDLCLRSVVTRTGDYHASVENVLETVFELMSHDGVFNQAFLPKTVRDSRGSVNDHAAIISICVQHWLVQRQNNERSLNRVPSEIIKDGSEAVETYLKDLRAGGVWRRKVCVVGSSGVGKTSLVTSITSMTPTLVDAEDHTIGVDLLQYTFVEEGIKRREHEVTFWDFAGQDEYHVAHTLFFSRRTLYLLCVDVEKFDREVREAEACETEKKAESKMQSFVEEHVWRWVRLIFARQPDAQFVLIATKADALGDNSNTHMKKLEARLIAILNEFRRRLAEELERTINASSKPSGRSLPSDGERTGELQTLQDQLKRFPTTWVPVNICNLDSIRHARSSIEQEVIKSDRCFFMGDKYSRVLKKVQEWRSTPKGSTKDQIEGCFVSVSRLRQSLMADIHDLLEDEATSILKALHNLGDVLWYARDGHDMLGDTVILDASLLINFIREVVCHDPKKIARTKTTNDSRIEALLEEMNRNGKVAHELLRYEFSLWSQLAYPEQLLQLKQLLQHFNLAYPAGGGKMEMDSDLIVPAYWRSYSQPTDITKLERLHFSDAEQRYHWEYDLGENSSELVKTVFEQLAVRSYFVFPDRAIIRGQCIESISNGKLAIRIACGLIGERGPGIRLEVIGELDQNPSVWLRGVHKAIEEVLVMFPGILVTRYALVIDRFENIDVLIQNLRNTQENLRAAKLRECKWLPDGVDHWFRRTDEEVWFISPDSIQVSSAFAEGSPGTLAFTATWLNSEVVVKVVKETEIHQFVDEVKLWHGLRHPNVVPFYGANHQEEPYFIVSMYASNHDLVPYLRGKQPHVVWQKLVEVAAGLSYLHNRGIVHGDLKGNNIVVSKDGTAMLVDFGMSFYESGSSSAVDEKKNSLGAMAWRAPEFVTDAKTLTTKSDVYSLGMCIIQAVTLNNPWGSYTNDAIRENLGRGIIKVDKPEEMTNAQWKLVQQMIAPSPNDRPELDEIIPKLTEFANDAMCPCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDX3</accession>
    <name>A0A8K1FDX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDX3"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="12">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="11">
        <location>
            <begin position="459"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="81785" checksum="69B871BDB32F03C1" modified="2022-08-03" version="1">MVVHMQVLSVQSVEMAPSLMLATETQRFLFNVGDGTQRMCMEHHVRLAKLRNVFLTELRTHTLGGLPGMILTVSDTGKDAMYIHGPEGTSQYMHATRHFLFRPNFKLEAKDVPTKLGVIDHKPAYEDEEVKVYAIPVRARAGAKRKLNDTAVVTETGANDCVSYIVETLEQRGKFLVEKAVALGVPKGRLFGDLHKGKDVTLPDGRVVRSADCVSPSSPGAGCAIVACPSKNYVEELTTSPLYRRYQQHAATQDGKETMTQPELQLQVVYHLGDASVLQHPSYIEWIKRFGDDVEHVLLNYSGCPEKTVYRDSAKLQAQLHSVFPDAFPSNDYELRDAETPFTRRVDMPFTSKPVIIGESMLKYTLTPTVRRGFDATHCFQRLNYDEIQQSTASFRETLTQSEAAAATTADALAAHLIGRLTFLGTGCAIPSKYRNVTGILLEFPSNAADASAPWHGMMLDCGEGSLGQLYRYAQGDMTKYRALLKNLKCIWISHNHADHHLGIARILSQRTMEDEADEPLTIIGPTPVEWWLKEYAQVDPTIVGKYTYVDNFHFDQQDDRFTDSVPAAKLTRVWLQDALQISEFECVRVKHAFRAYAVVFTWQNALKIVFSGDCRPSDQLAEKAKDAFLFIHEATFEEGMDTEAKQKDHSTTAEAMAVGQKAHAKHLILTHFSQRYPKMPALDASGLDDAMCAMDLLSLRFSDLHRMASRMELCMQIVGMDEDDNAQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDZ1</accession>
    <name>A0A8K1FDZ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008735</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDZ1"/>
    <dbReference type="OrthoDB" id="10002959at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480248" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="251"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="531"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="935" mass="101523" checksum="00B5C4AD2948C69E" modified="2022-08-03" version="1">MTIVMRLGGGGWLLLLLSAGAALAEDRRLRDNETAITTGVPSPNVTENVEYIGGREQSQLSSLGEHRYHVALLSEAKEKPSEWLQGCLAFAIAPSFFITRASCVMGNTVPPSLYVETAEHHYEQFDIQETKTHPDMEVNLAIFQVVGSVLTTIKPTNLIEMDPAYYDAEPSLVYRSLDMLFNPSAFSDRPQEVFGLARVPVDSCQFGADPDTVHCYAPSDVMSRQTAFSFDQGFLTWDDDGLVGLPDCAGLCGGGMFYSTTHLASFKPWINDVTGSTARWVAPDSTKIAKARLPDAGVSLASLSFGDSEALCEGTLIAPRFIVTSASCVNNGTVDTATIGIGEYQKETEDKVPVERVYIHPWFGKGTEYSNDIAVIELKGPSLYSPMMLVSNDTLLPESCELAKPFSVSSVDGSLLCLHQASSSNATRSCHTQVRHRTSKKQGDGVFMAEGQSGLALVGISLGFEEETPDEMLINYVCDGFESKGGQNLTASTFIVRLATPETIEFIDSVSMDHTWSHRGRQPVGPLSIFQLGSHAKRKPAPYTGELEFEDAPVSAALGFVVGLRTERYGQNFCGGSLIASSYVLTAAHCVQAGSVKFVSVGSHDSAGKETEAIAVKSTNIITHPLYNQRSSFSYDVAILELETQAYPKPITLDNTLELDPTMYFTLYGYGANSASNRKLSNTLRSVDLPYFPRKKCRTSFPELDESMFCAGGELARDACTGDSGSPLIRMVNGQPVLVGVVSSGRNGCGTPGVPGVYALVAATQRFIDHCVAGHKWLDPATTGSQFDHMGPDGELELGSASKTQANSNTVMRSYQDENASLPFEIINMANGSFQRQLSIVELARDTPQRLVGAVLDFIIGHMPRVATWGVWTRDNLRLTFYSTGNLTGIMQTIARRGKQPLYTRQNRFNRPKPSFLGMNDQTIEFTAVANATCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDZ6</accession>
    <name>A0A8K1FDZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013254</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDZ6"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="11">
        <location>
            <begin position="328"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="695"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="877" mass="97673" checksum="38425AC687C651C7" modified="2022-08-03" version="1">MEHVEEEATLRALLSFLDSVEGNALVDPSLSPDASDQSPMVSPKHSPTIETRVPKKKRRNRLKVEIDDLREQARELETQLAFLRSHRGQANAQSVAVSSTSSEMVGMWKNVAARQFLQRQEAQLLNANLRDMVATKAKILDSITRLTQRGGILSKSQMEQANSILRSFQDWKPSWISTKYTHLMAIVEAMYEHRDFAFPVDMFAPGDLHCVQEQGVSPRNEPVFLNVYHGFLTPLEYHAAADVIANVLGGPTRVITRGHHNEDVWEHGVSMTVSSANWPEVCHQVITGRRFAVNNRHLILLAGETYASPSVPYIFRYEKWIEIAPFAKGTEHLQKDLARIAGVSNKTDLFKLSGDLSPIGHKFLVEARVNAGMKNVSTNAFYIGPGSLVLPDKSIYLDNATFAAVEPFCRKYISTILTLASNSSDNQSHPNNTSNTTEAEDAIINIEKSLATILPTGEEEGIVNIYNPVKYSDAIKEWPLTFGALADGIRLTELSSLNDTSNVIVTTPAYFDRAEKLVDIIDVKDLKIYLTFLYLNSCVSYLGQPFLDARFEFFEKNLSGSLAMPPRERTCTEAQITFFPVLVGEYYAQKMFDASREEYANLLVASLDSAMADHIAKLDWLDDQTRAKAEEKLKMITNHVGRSTQKKNYPFTLTRDDYLLNVLTIKNNDWAESLQKIGQEVDRTEWILSGATVGAYYTPTLNQIIFPAAIWQPPFYRNDSHPVQNFGAIGVLVGHEITHGFDSNGRLFDGEGKQANWWTNETALEFATRAECMMEQYSSFTVTGSNGTPISNVNGNLTISENIADNGGLGLAFDAYHAWAKSNGSFDSHGVADDEVDKLFFISLGQCGAPAFVIAMPSSSCWLTCTRLHTGVWTALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE87</accession>
    <name>A0A8K1FE87_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE87"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="512"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="5">
        <location>
            <begin position="609"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="7">
        <location>
            <begin position="785"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1066" mass="117819" checksum="3312A5A8DFC167D2" modified="2022-08-03" version="1">MLFGPQYDDDASDRIVDPTAAALKKKKGRSARNAAPRSSATNLNGASTPIRGGGSKRLTTPTKLGAMDLDSFYSNSTESTSSGASFNNYYANTAAMATQAKNRRRDASGYSGRVLDTPARKQIFLPADLSTMYSTVWKGLHFRKKTIPLATSTSVKPICVTGVDGFLGSWIVCELLSRGYRVRGTVQSRNDDISGILSLPNAKNFTVVETSLLTPEACDLAVLGCDFVIHTGTPTSCSVRDPISEQDEPGVHSIGSRMHCIIPMMTNFIQACARARIKRVVLTSSIAAMADAVAPNSIVNETSWNITSSLERNPHFLSLKLAEEAAWQLVDQLPREYRIDLVTINPGTLFGPSLSKSKLAPGNHIIFDLISGQYSALVDLNWSMVDVRDCALAHVAALENLEARGRYICVNRTVWMKEIVEILANNGFSGRDLPWRVGLPNWVARLPAYSAQLGQVGASLYANDPSNPRSSPYLNEKVIDNLNIQFESVKKTIVESANDLLRWGLIKPWAEDHESFECNICEIPFTFYRRRHHCRECGVIICSDCSKSRAVVEGTDGKVRLCDRCVKSSVPGLLEMLSEQNEVSQRKAVVAIEALMDNEDNHDYVTRYEGVARLMKALHSSNEVIASHAAGALVALSTNVSSALQMVLEGAVLQMLEVEETTTTWAICLQALRNLWKQVNRNDFRKMLHAVARVSTTTNKGDLQGNILLTFVHMMDPTEVPTLLSEGLLGVLFEMLQSESVFPRCAAAHAVKHLVPASYNPDLTIDVPPYLVDDHEELLANSSLSDLQFLVKGSIAPINAHKVVLFFRNSYFKNMVRFGSATSQTGMIEIDNCSYEVFSILLRFLYTGKVHITPNIAQELLRASSIYHVYELQKRAEHYLAGEIRVDNVVDLLTLAEECQATDLKRNCVPFLMRNIHEVVGLPAYRDHRIRTSDEVLKALASMLGEEWEESYNKLMQTIRDEKKDIKESSDRSSLMRGYSIESDSDMSKVYSGGLMPSFMHAPSSNVNSGGFTAVSNTDLPHLSDLYVDPAPHSSYMKPFGAGDVLFRRSRGLSEDFSEPLSEGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FED2</accession>
    <name>A0A8K1FED2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FED2"/>
    <dbReference type="OrthoDB" id="10619534at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="189" mass="20771" checksum="4B34BE636821904E" modified="2022-08-03" version="1">MLRMKPMRKAQDLSTLKLSDGEKSAILAEVSTLLAETLTYEHIYRNGAGPLDSSKWKEVKAKDNFRLYKERKPSSTTTTFFADDVGTRGIIESPTLLSLRDLRSLSSSSPTASSATDKVESIITNIKHPDVPLLIAAGHVEGSLEDIAFGGMASDELAWRLRTAYMKDNFSDTKVLATIRAPTTDAPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEG5</accession>
    <name>A0A8K1FEG5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEG5"/>
    <dbReference type="OrthoDB" id="64552at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="407"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="952" mass="108861" checksum="13FE6286399EE1F7" modified="2022-08-03" version="1">MPIMPSMERSSVSKRRGDGARRRGNAREHAASSQPGVPPAKTALLDEFRAHEEDCAARVLQHAARGFLGRLLVTKLLLQVYRRQYDPIEKKYFYLNTQTNEASWAKPKALELFLPSTKDVQAIKDAVLTPPDAAKRIQRVARVFLAFRSMKRMLRENYMKLFNDETRTYYYLNTRTGATSDHPPPFLRQERDDLPVEMFYFRRAVCKLATRSNPYGSGVLGVFGSMLCMLSDGQTLLNEDSALHAHAVCNYSHGSVSFAVILTPDRFFLRFEAVENTFFTLCAVDRAHFESLAGENIVPVRFELNDRKLGCVDSSMKTQDPIEVVGHPYGKLQVIHQRVLVKMVPHSISPLRLVYDREMECGAAGSAIFTRGGRLLGLQSFTSLKEPPTEFVYIRPVLQTAITLVTPPEPILLATCVASTEIHTYWQIPRWCKPIRGLELRYELEYCRHDAKHVLHHTQFACVYVGTRKSKQIGELQSDTMYSVRVRSAHAMAKSSWSAVLRVITHPTPSMAWRVLRYCTSIADATQRLRRHHEDVAVHLRCVQWLLRHVNAVLTASHDAACNAMEQELITCETLEVLIDATRRFPDDKASRLLTLELLRALTARRARTQQFLSTLPRLGWLVMLLREFYSDVLSENSTATELLLTALALLGHLVDDNASAKQLCEVVDAIPFILSILTEDNGNTLQTHQICVAESCFFLGRYTHNHSMRGKWIIVDSQGIRVLCGVLTRYETDATIVYWCLVTLGNVAYGVKEHSNAREQLEAETNAHHLIDIVCRVKMLYLVRLNELELEQIALEAERERLQANLMDETMRNDLDACELSILTVQRVINELKDHHVGQAADFALHYLLTDEQCRVQQASQRLIKKFLLRKLSMAVATWQTFTIFERNCAIMRHFLTTVRHRQLSAAFRRWEGIVREWRKHKTLLQSIGAGLAIDLNKKKREHYRMLVLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEH5</accession>
    <name>A0A8K1FEH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEH5"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.210.12:FF:000001">
        <property type="entry name" value="GTPase Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008956">
        <property type="entry name" value="PRK12299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="6">
        <location>
            <begin position="127"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="305"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="481" mass="53395" checksum="C3A6B19F4A578648" modified="2022-08-03" version="1">MLRLNCLARAVSFTPLRMGRKRNGLLRPSTAGSGQSASFSVRGGKKDDDDDEDDDDDDDDEYMEEDWDDDDDDLDFDEDDEDLDVMDEWMDEVNGVGAEGFAAQTKRKVEEHVKQKVSVRRAKHSKRRFVDRIRIKATGGHGGNGCASFFSESALRRRPNGGHGGAGGNVIIQADHRIQNLANATHHFKGGSGLNGMPNDAAGRRGKDCIVKVPCGTIIKRVDRYERDLDDGDFEIVDRMHPVCDLDQHGTTFMAATGGKPGLGNRILAGKTTNFGRLRKYMPEGKGTGHPGTSQYYELELKTIADVGLVGYPNAGKSTLLSRLSRATPEIAPYPFTTLHPFVGIVDFPDTYRLSVADIPGLIEGAHRNVGLGHDFLRHIERTKILLYVLDTPGTEGRDPLRDFEHLQRELELYAPNITTRPSLIAANKMDERGAEKNLMRLRGATDLPILPISAKHKVDIDSIARTLRWMLENYTKLTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEU4</accession>
    <name>A0A8K1FEU4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEU4"/>
    <dbReference type="OrthoDB" id="75582at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="891" mass="101836" checksum="C1DF918E05AB4837" modified="2022-08-03" version="1">MQRERLEGWMVRQIEQADLARDTVIQMPPRPMVAMAKSPFSSPRGAAAPEAPRRRRFGHDGPPRRPYTTPATSRTRDSSGGHDTNHRTLTPRTRLETAVSALAEPDGHDSVARQWRLHFQDPEGCYVEEGSVDRTKVLKDFGWGSPRGEASQGAYPTSPRNDDGHDGFPDEYASRTQAPSSPLALWSMPREYILEYIRQSIMPTFCATHARFTGEWEAVLPSDPDNRYVPRETELVSTPSAALPPLGTQRATKASTIMGYSSPHSPRHASQSSVVSVRRSAPAASAPPPTSPRVRPPRCEERIQQILQELRADPKLLDAFQKEVKQYLDERRQKQHASNKIRENRQRALLSPRAPAILAERKRRNEDRFERTRRQRQQLDQQDSVRRETLLMAFRQKVYGKENPENTVDVTLTASYRRRKMWLVVLAFAKASTQLRERLLQTKQRQIVERMQIKAARTIQLIWKRWKWRHASQHTVVIYSWLRKCLWKLLFRIRCRRKARQGAILRRFLLDQCTSSRETRNFNSMMLRWRSKVIHSQRHGMNFVLCTRARLHALSIWWDSIDHERQRNERQLHDKLLPTTDEKEAEWNAIIHNRRLSMRSSAMGASSRALNFAAASPPATPRPNSPSPSTTATPTPVAPSTTPGIPPMLSRRTTSTRQILDQMGGRLTTMQQVLTPIEIQRLQQHAFHVVRIPRAIKMRLLVEHLTQIRKAYVRQLTAYHDQIACSSYAREVRLDDARAIVQGGASWDALLVDSRTGQPQIRKPIFQLYTGEKLQRQMEELVRRGVMLTLESDPAQRAIVDRQRQQRQAFEAAGNTLGPSALGTSVNSPRVRVSSNPGMAALNGISLTARPPTPPTLALDLTVSNEGEPRKRPTRKLQFALPAAIREKPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG76</accession>
    <name>A0A8K1FG76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG76"/>
    <dbReference type="OrthoDB" id="166596at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="400" mass="41895" checksum="87EACBB223162709" modified="2022-08-03" version="1">MVSTKYMIAAAAVSAPLVHGHGYMGLPKVTFVGNGDPTEFATTINGYKALPYTLPLTGSFPTKDSVYSTDPTSNTKYYTQAIEASQYKSLREFILSQAPNVGCGKTKLADKQPLPDAVEWTHGASEGFTPSHEGPCEVWCDDEMVFHDDNCSKNYPSAPAKLPYEKAKCVGKSKLATYWMALHGADWQVYISCAALEGGSGNSGSAPSPAPGNGATPSVKPATPASSTPAATKPAATPAPAPSSGNEYDDDCDDDLPEPGDDDCDEEYPEPGDNEVGGDSDYTPAPTTKPTNGGNNGGNNNNNGGKPTPTPTPVVKPTPSTPTAPGAGNEYDDDCNDDLPEPGNDADDCDDDLPEPGNDDDCDEEYPEPADNEYGNDFDFSSFPGTAGAFTPGKVVPENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGF0</accession>
    <name>A0A8K1FGF0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGF0"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000753">
        <property type="entry name" value="CAMK/CAMKL protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="277" mass="31687" checksum="3ED16041EA8D5D4F" modified="2022-08-03" version="1">MSTRHSQFRLKRKLGQALYGDVWLCEDTRRENHDVVALKEVSLQTAKEALMRNPHMDNPWQERQMTRLIQKLGEHPNILQFHDEFVKSGSWFVVMEYCNGGDLFERLQNNAKGRFDEQMALKYFRQIAEGVSFLHRNEVAHRDLSLENVLLNDDGCKISDFGLSTDANRRCVERVGKSYYMAPEVVAADEYNPKAADVWSLGIMLFIMLTGSPLVQSASRQDKAFIALETFGVHKILDVWEMSSSISASTMDMLASMLHVNPAKRPSVEDVLAKCWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGG6</accession>
    <name>A0A8K1FGG6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGG6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="46586" checksum="FFC6B357CF20161C" modified="2022-08-03" version="1">MWVKVKRPHEQNKVSPLQVLEVMELLRVMAAKEPKQWPTAVTVIHRVANQVDLTGDSIAWSISFVIDVVKQTDKGLLAALQSSNTQWDRSEAFQDAKQAIGGENGSLGTLKPTPVCLRASSASKEEVEAFLNDVNAVENGVDGLQPAVFALESIKMTASDPTTVTLLANTLSTKLYVHELCLTASAFASNDASSSNLSSVLTQLLSRPIETLQVQGEIAFEELTTLCLVLRECQGVKSLHFENVLGVDDRETSKRWRWFAYALFSRDAAHDIESIALSEAELKFYHPDEVREIVTAPDRKLLLDGGRQYDKPQPDRRRLESLILRFDDFNPDDYIEALSELVSTLLMVTSPQYFSVLCADPHKYPMNQDCLSNMGPLFGPSLSKVTPEAIVSAFAEDCDLRSLVLHDLYHGHEKLVRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHS3</accession>
    <name>A0A8K1FHS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHS3"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.40">
        <property type="entry name" value="Cytoplasmic polyadenylation element-binding protein, ZZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038446">
        <property type="entry name" value="CEBP_ZZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018553">
        <property type="entry name" value="E2_Ub-conjug_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057668">
        <property type="entry name" value="E2_Ub-conjug_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560">
        <property type="entry name" value="UPF0652 PROTEIN C16A11.03C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560:SF0">
        <property type="entry name" value="UPF0652 PROTEIN C22H10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09418">
        <property type="entry name" value="DUF2009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="654" mass="73914" checksum="D389AE2C9AA2EC65" modified="2022-08-03" version="1">MEPTEESALTRLDRMRKLSALLDDAVDDEDVTAETLALLERSSGRANAVDAGVDDDMDDVLEQTRKNAFECVECRAHAAEVFCEQCHDYFCELCYGGQHRKGNRRTHTFQPIVPVEPSTTEQMEVTRESSDEEPDEDEDEDDEDTSETSDEGDGAFATRVLPKLLTNGVPKPSAITATGSVSVAAANATVRERAKYIPVRLTYEERKLLRTLEAALSVSHYTDKLDSPAYLAPAKRLRTQLQEICGFLSGVVVALDYQHGQEVLEDKTFVEKQALFQEIFELGRRYKIMNPEKMRGEYGKLMYLVQDAMTAEIQELLGFSCHKKIRTVYDILEKAQAVGVLDDPKIEIATMVVAPEGKSRVQIQREIKLKEQAIREISARYANSRIDRDGIQQCLYSIADNNYHLYFERDPIDRMIQLLTTHFNPENEETEAQYSLAIVSGQDGARLSHSHQRQYHYVLQSLTLWREIAHDMFRLWCLTDEDLLDGATKYTLADTGQGLHRIQPAPRVSRAMHVILHMTQRSLESWVGSSVIHLGDKNVPNALMFIDKYTQVGHILRPIVKTVDAIEPLCKSNPKLERYIQTSFGGAAALRRAILADFFREAFDGSGADNFFDAGSCIDGRLTSAWNWCSHLHEKQFYPVFKLAGFVGFDGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI14</accession>
    <name>A0A8K1FI14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI14"/>
    <dbReference type="OrthoDB" id="121008at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="285"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="548"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="680"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="755" mass="83997" checksum="A4439625A1B52442" modified="2022-08-03" version="1">MSIHEDATLEFPLDDSFFPQVVLNADDVKRFKRLGKERLSTLLRMDEDANEGVYAWKEVKTRYAPNVTVQAAEFPVFRPTTKAKFMSTLLQSSIVLRETHADEILSVLAPTKTSTTRKTLAYLHRENFVDAQMLLKFPTSVQRSEFSYRALKWCAFRVGPHRKLVDFALLEYTGHRKPTSSSSVVAFCLQESVERERELPSLEEVGVVRGNMTHSGILIAKTHQPNAFRVTAYSQIDGDMDATQRHLMLELHQERMGAILSRLEGLVDRQRINSLKILEPWQFPPSERKACAVCTKKFFLRHKHNCETCGEVVCSSCGPMRDIEKSNGSTKEVRICQACMMRAARHVAATLAATSERSAETSSVASSESMNRPNGRYDTMEDVKPKKHHDHPHRPHAPPRPHGGAHPRANGPQLGPPHERAKALQEILRRTRQLHSSISDRLSNGDYYETLKGGDDDPFAELDAQVRGLRVRSDQAEPSSARQSGLRDSDYRQQDFSDDYMDSVAAKTLRVATATRRAAANVLSTYSASSSEFGEREVDSDGEDVSEILASIGGGSGSRSRSHASSRSSDTASYDRLQRRIPGRQPTSARRHLEMRILDLDRELSRAQRELSILDIDDDDVSVRYPSISYKAPSSARLSIPRASTSTASSGRASLTVDPAMVRELYSVMNSDEVTGPVLPRRRASITSGSSGRSSLSDSIEPFERVPSMPRARAPAPPRPLTATTVYIDSDGQSMVSSPHSTASHQSRQYLAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ88</accession>
    <name>A0A8K1FJ88_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ88"/>
    <dbReference type="OrthoDB" id="167943at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="326" mass="37057" checksum="2E086D0C2A56D242" modified="2022-08-03" version="1">MDSHAASRSDVFTLPPNVGPWHEQRSVCPLQPIYQANKSVFAITSLAEAHGYESGEDTIRTASDGTLIPRSSRKRYFPRAQRRFRDRLQLLDERLRLDVNSLKQEILDLQLQHRLIDTRHRVQRHARTDAAVRVVQECFEAFRSGIAGADDPKDLKGRQERFLADNMDENMRFGRYRDGITILMEQWRRYTLCHREFQVRLLHIDTSGAVSPTMPIVRADAMISGYITHETMSTVFPRVIELYPHLAALMVGALIEYPSLVTFHFNADGRISELDGEVDFVLPLAGVLGSLRDAALVLSASTIHEQCLIRSTSETTAKTRTRKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK04</accession>
    <name>A0A8K1FK04_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDAN1-interacting nuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK04"/>
    <dbReference type="OrthoDB" id="1272at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029404">
        <property type="entry name" value="CDIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661:SF1">
        <property type="entry name" value="CDAN1-INTERACTING NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661">
        <property type="entry name" value="SIMILAR TO CDNA SEQUENCE BC052040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14811">
        <property type="entry name" value="TPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="344" mass="39283" checksum="8AB9732FCDB44873" modified="2022-08-03" version="1">MDEAEYERVCALDAYPVAADGGPGLSVSEETFAVIKRQVEHRRLRGALRQHRQDKTLKRYIARHGSMEEDDKRALHQDNKKKTSKRESFCAIAQSVNFSPCMLARVLLEAKYGWTKTMISNLFKDVMSGNRRWPLRMPAQPSQDANGERKIMLEAEYDRLWKEIGECIYADPYCSPLADRIRHNVGLEYEYILTAKLQSRGMVFESEDVLREKGLSKTPDVRLVLPIGVRDKEGELHVVHWIDSKAMFGDRHTHETENASQLQGYVNRYGPGMVIYWFGHVANLSSDRDVFITDAFPTDFLLPGDLDPFEGTPSLSQGDDLQLQHHTVATSFDDDFHPMSTCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKG7</accession>
    <name>A0A8K1FKG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKG7"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="566"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="395"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="320"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="625" mass="69516" checksum="B928F3ECF8B0CA26" modified="2022-08-03" version="1">MASHSTVGLPSQARHAAKPPALSAAVRSVFGAKPSVGLQTMDGLPLLPSHVAAWETPADPPVETSEDTELFGERSTRDGIRKGLVQFYESTGQLKADGAVTEMTLRMDTELELLRRQCFAERNARWNHHTPDMFTYAVPVKETWAPVPYMGERKKRQLLHKWRTGEEKNDEELSEYCGAWLSVNDEAVRERPWPPKEFAFKPNSKPGRGSGSGNGNRLNGKKKVVGMASVVEERPKYARMCCVCQTQSSALWRKRPRPTLTPALTVVAIANGTTPNVDPTAVLPTPIVPAPTATPPEEDDICLICYLKTERKDIFEKKKAEKAKKAREDAARAAAEARQLKKQQQQLKKKFKKLVAQQEQLKQEAFGSETVASSASSHVPDILRLDTSTFKFNTDSSSGVAYSDAPEEKKRREKKSKKEKKKKKKKKKKKDWDSSDSEEGEANTSLRIILPSPPQRQMDGYVYADRPPSATMRDEEPTLVKQEHEDVDDSRAAKRPKRTSTPSASSSRKRKSSDAIIEPIILHLPPAVSPPPTPSRPRAKQSTDTKKRARPVKKEGARERELRALGQYCPVCNMTYEDNDPSPFVCCDSCEMWVHAACDTSLTPAALAALSESNDKYICPLCGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKN6</accession>
    <name>A0A8K1FKN6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKN6"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46731">
        <property type="entry name" value="F-BOX ONLY PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46731:SF1">
        <property type="entry name" value="F-BOX ONLY PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="438" mass="48555" checksum="99ECD4154299368F" modified="2022-08-03" version="1">MERRNRPMLLEPAAPRRISQLTKGPESRLPRRSNNQIASDILSKAPVGPIATKTFVGANASAITKKKVDEIFKRLQPHSIVQGYDKAQIALKLDATFIVNGETLSVCDPSDRDSIQTKWLSQQATPSAKTAASRPSSFHYAQCLDFDSPHVDLSLDTIKQLEVTLTSRATSSSTRLFSSTEPLTKKAWRLVAETDEKIGLALYEVSFGPWNSSALLVLAWKQRLQIAHFHLQLHVPEMLYCCPSRMIRILPDDVDKSYGLHSYTTAITLRDCHSVFWESECYDISFGSFAAPASGKQQVAQSELLDSLTGYRDRARYTTGVPGFAVSTEALSFSMENALIVDFCVWDASCNPIWGFTRSLAVLKRATTRTADDFSVSIGSGQRDLGELSYTDATRGNSLIIQLETLQGDKGKRIFVKQITVEFSAAFVNKTFGTNYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKX3</accession>
    <name>A0A8K1FKX3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_004291</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKX3"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="206"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="512" mass="57991" checksum="F07841A992644A9D" modified="2022-08-03" version="1">MADDAPKEKKLTKKELRILERQKAAAAAAEPKLTDTYGELPLIQSQEKTDKVFKNVGDINPEVQGQSFWVRGHLQSVRAKSKIAFLVLRQGTFSIQGILNESDAVPREMIKFAAGVPKESVVDAFVTVSLAHQPVLSTTQKDVELTVQKLFIVSKSLPELPFQVEDAARPDALVKAEGSTYVDVGLDTRLNTRVLDLRTPANQAIMRIQAGVGRLFRQFLESRDFVEIHTPKLIGGASESGANCFTLKYFDQDACLAQSPQLYKQMACACSGLERVYEIGPVFRAENSNTHRHMCEFTGLDFEMTIKDHYHEVLEVFSDLFIYIFDNLESQYARELAIINEQHPFEPLKYNKPSLIINYEEGVQMLREAGVQQDLEEDLSTENEKTLGRLVKAKYNTDFYILDRFPLAVRPFYTMPDPKDKRWSNSYDLFIRGEEIVSGAQRVHDPQMLLERIEKFDIPQEGLKAYIDAFKFGALPHGGGGIGLERVVMLYLGLGNIRKASMFPRDPRRLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL50</accession>
    <name>A0A8K1FL50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL50"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF15">
        <property type="entry name" value="DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="190"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="298"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="414"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="612" mass="68597" checksum="470CC41E56FD9499" modified="2022-08-03" version="1">MERRAMNAAVEMNADVGVDDAVMGLAVNTRNYQAMLASSGIKKSSGSKANDENRREGENSTVVGIPVETRNYMALIDPKTRDSTNGSQQYRPSSGQASSNNNTVSETEDEDAVMGMPINTGNYLAMYRQDSDMKVRHRGYSDLAGNSGDRAHERPSAVGRRSTPEYSTASSSQSQQRETCFDPRRASGAVVPHSGWIYAQSPKMKAWKKYYAVLSGLDFRYSKEQGHSPKGFCTIQSVRRWDAKSHGVTVVCTSGKEMQFYCSSNTEREEWLTAANRSIEKSQHSSGNSKTTYVLTGGESHDGYLFMLEQRNRSWRRQYFELRNDGYLICKENENNSTIDKRASGYLKSVAFSPEVHPNGLVMQLDSGHSIFVYAETYDDRMLWYAAISAVVSANDRTPHRSTSVKSTYVQSARSNHSGWLFKQAGVFKAWKRMHFSLHGTEMGFAKDTNAPVEEYEKIYSIEEWDGKQHGLEIRLVSGKIWRVYAESYESAKAWRNLIGDAARQAEHFTIKRYLNSRRRKRLSPVFGGWFTTTSAIGVRLRRFYVMDGNMLGVADDVDHLLQPIGSVVDVGATRDTTNGMLIVFADGARLKVSGDSVESAKAWFECLNATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH7</accession>
    <name>A0A8K1FLH7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Selenoprotein T</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012272</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH7"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019389">
        <property type="entry name" value="Selenoprotein_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13544">
        <property type="entry name" value="SELENOPROTEIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13544:SF0">
        <property type="entry name" value="THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035441285" description="Selenoprotein T" evidence="4">
        <location>
            <begin position="32"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21991" checksum="9CADA295FE39EB06" modified="2022-08-03" version="1">MTRTMSMTRRVLALLALCVFVLSTAMPMVLAKEAETTESVPTNHNALVDDEVRVFFCSSCGFRQNFGEVKQYLEDKYPHLVDRIYGENYEVGPLKNLAARALGVLQLVGMVLLVAGEQIFRMLGWDSTLLQKALDNRIGCFAVIILIGSISQGLVSTGAFEVYYNNDLIFSKLQAERWPTLNELSELLEAKGIRAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLR3</accession>
    <name>A0A8K1FLR3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLR3"/>
    <dbReference type="OrthoDB" id="9986177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005246">
        <property type="term" value="F:calcium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002115">
        <property type="term" value="P:store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000074">
        <property type="entry name" value="Stromal interaction molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037608">
        <property type="entry name" value="STIM1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15136:SF13">
        <property type="entry name" value="SAM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15136">
        <property type="entry name" value="STROMAL INTERACTION MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="191"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="452"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="73039" checksum="074F51CE105EA60E" modified="2022-08-03" version="1">MRWTGEARARVSRWRLCARLVVAAVVVTLTLVVPIEGKAAEIRDSGGFNGGQDALETLASQGESLVEMEVLSDASTIPTKLSLDEIERAAKAEEHALKEARKRQQPAVESLLADFDNDGQVGKNEIKLIKENLHHIFDIDESGSIDTKEIMTMVKDDKDVQSAFKKLDRDQDSVISLQELDERWESVGAEMTVSEVADWVAYSAQLPQYADLFRQNSISGYTFPLLMQNDGARLREIGIESDMHRQQLAMFIQMKYLGMGQKPDTVRSSHCNAEAMTPAIAGEAKKAVLYLMWEPADSIPQRYQLQRRSPGESQWTLVYSGPDTEFIDIVDHDQHVIYRLTTWNSYGRSPNIFVRCERTKSMSIEANHPPSLDSLNAASTTFNSQKADATSNVKDQEQAQSEESLMFILKSYLWWLDEAIALTLFIVLPIRGFIYGDADYILRLFRRLPPNMPTRVTAEADSDKTTITDAAVTLSWEKPVDNGVPIVCYTVRWTRLKTDEVQWLKLLTLPLPHSVTIEHLRHGETYKFIVEATNAFGLVTKSSRSTYMVPVPELRGKLVPRGSSKELTVLRNQCYLCQANRNLAASERKRIPFSATLDRRILHFCSRCDLEFCHYHKGEVFHTKALSCPAVDGKCICQRCYEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN56</accession>
    <name>A0A8K1FN56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartyl protease family A22B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012940</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN56"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40234" checksum="D37DD5C2DB7FB2CD" modified="2022-08-03" version="1">MLNTIQSVCYVVLITLMVASNYVLIPVPVQLITSATAIIYIGATLSLKLKHHREASGEKNDEVMKAEDAYMFPLLGSGVLFGLYMLFKIFDKDLVNLLLTSYFALIGTYSLTEAFSPLLKQILFSKNKSSFQRNIKIPFYGVYELVLTPAWMLTFVFAAAFATAWFKTKHFLLNNIFGISLSIKGIEALSLGSFKVGAILLSGLFFYDIFWVFGTDVMVTVATSFDAPIKLIFPREFATATEKAKYSILGLGDIVIPGIFIALLLRFDAHRANATATTQNFPKPFFHVNLLFYILGLVATVTVMFVFNAAQPALLYLVPACLGSAVVTALVRGEFKELLAYSEEEEEEEDAKKKETEAKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNA5</accession>
    <name>A0A8K1FNA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008314</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNA5"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419534" description="glucan endo-1,3-beta-D-glucosidase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW65672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="33536" checksum="36075CFE38D84C74" modified="2022-08-03" version="1">MKPLVVLLVCLANFAKVKAHGVCYDPNHNKPADADAIRKDAQRIKEAGFKSVRTYVVKFGPDNLASLLTEQGLNVSVTIPFVNERPDDSMPEMLAAVEAAIKPVTPGAGRVTQIYVGNENLANVNAVPPKMFEFINYVKGAVPPDVLVGTVQRNTEFLEPARVDAIAGWKQLLDGCSIVGVNIHPVFTANTTAERAIDVVNDQWIQLTDEKTKQRFPGIVPKYAITEVGWPSAGSMLGNTGTKEGAQDFVNAYKTWSKKHIAEDRSFYFQMFDQPQRQDGPFEAHFGMVDASGVNKFTSFSFQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNV4</accession>
    <name>A0A8K1FNV4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNV4"/>
    <dbReference type="OrthoDB" id="117367at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="329" mass="38285" checksum="7C5D713072E3A7D7" modified="2022-08-03" version="1">MGRNKGRQCGGYTSKMERFTLQRLWQRQVSKVVTQRRQERVRVDVVKALMNARLKDDQVEQIKLKRIEAITTELQRSTTIQSFATLQDRCLHEIAKTFDLYSSTCPYTREFFGSFEPWMITRLSELTTAFKTMNDDNVLLLLQQTIDDLTIGFIRQEQSLALLVEDTEGKQQLTWQRSGNIFLGGHHEVESWDELDVEEVDLVQTQDDIHLRSLKLVSCRGLSVDFLARLTQIHPYIEHLEITDCFDAVDGEEGTAIMRQLVQWRSLKTLRLSWCSWLTTECLVAFAYQLLEPPASGLEELHVSHYFDVVEDYVRSIYEDLLPNLQVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPD8</accession>
    <name>A0A8K1FPD8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPD8"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="39521" checksum="9CEC31D657AB36C8" modified="2022-08-03" version="1">MQYRFLGNSGLLVSQFSYGCFMTMERQLDFEQSLTILERAFQLGVNFFDNAEIYANGTSEQVLGRVIKAGIERGTWTREDLVISTKMFFGSNLANLTGAGGLNKQGLSRKHIVEGVKASLERLQLDYVDLLFCHRPDPCTPIEETVRAMNYAIEQGWAFYWGTSEWSAGDILEACEIADRLGLIRPIFEQVQYNVFERSRVEYEYAPLYQEFGYGTTTFSPLACGVLTGKYSKGIPEGTRLSIWRYKHLQDVIAQQTIKAVRLEEVAQAVGCSLPQLALAWCAANNNVSSVLFSATSVEQLEENLKAAEFVHKITPEIKAKIDEIVDFQPKLIPRYHEQVIGVRGRYMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQG7</accession>
    <name>A0A8K1FQG7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_001560</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQG7"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF203">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="85"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW69404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="39038" checksum="C0887CE793D4C9E6" modified="2022-08-03" version="1">MRVNGFQAPFSRDQVTSWVLQPLMMSCFIAFVAKLLDRDKCLAILIPNAVLIIIILSSWYICEHRDPSQERSKDGCSVLSLPKKMTRYCTLCCKTSPGLDHHCTWLNTCIAENNYEAFYTLVVAATLQTLLQAVIGILMATIWFSEIKTQLTTSWHTPVLVLLWVHNAITLPLANSYFLLAGFHTYLLVIRSGTYDFILENGSDGICVRMLKCRCLMRSKKNKRKQSQVVHAQQKRRSISKTTPVETTTKVIVPPASQATSGFTQVTQNAKSAADKQREIDQWKAEWLSKYGGDDDDDSQPQKSTGAPVSRVESIQIQTDGQDTATEPQEVPENPNPPPSPLSQRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRN5</accession>
    <name>A0A8K1FRN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007425</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRN5"/>
    <dbReference type="OrthoDB" id="428525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000067">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF136">
        <property type="entry name" value="H(+)_CL(-) EXCHANGE TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9 11" id="KW-0868">Chloride</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="851"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW67753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="945" mass="106013" checksum="0603907B985B686A" modified="2022-08-03" version="1">MDASETEALLGKRSRRVKLSLSGRTLSARSDDVEELHEDAGVSSNTSISSADDHPHDGGPAPAYPLPRPHARPNYQATYYQSTPNDDFAIGIQRTQSFPDDLYSGGRFSRFEIEESLRKRQGTSILDWLNEKREQLKKRQKTPEHPEEQDHDKKVKAQHLESYDYDFFESRVNQQHEHEQTEESVRSLNMGRWIMTFSIGLTTAIVACVVETMTRVFSSFRTDTMERYVALEKDGAASFGMGFLIYSGISVGFVSVAAYCVAILCPVAGGSGISEIKATLNGIKIHRVVRFKTLFCKAFGLLFSVGGGLPVGKEGPMIHSGAVIGAGLSQGKSSSFGVDTSWTKFKGFRNDKEKRDFISCGAAAGVAAAFGAPIGGVLFALEEGASFWHQNLTWRTFFCAMVSAFVFNFFISFMESGESAQEHIFFGTLGTQNGSFSFGSFIGGKSYELLDLMFFILIGMLGGLFGACFNQANKHLTLWRQRMVTNRWVKLFEAVIIAFSMAAASFWLPYYFGQCQTRTGPYSDSLVTLYCPEGQYNDLASLFTVSYSTSIKQLLHFTEGASFSFASLTVFFTVFYIIACWTYGISVPSGLFVPSLLAGAAFGRMFVYVLHGMGIPIGAQDGMYALIGAASMLGGMARMTISLTVIILECTGVMEWGLPIMVSLMAARWVGNSFNEGLYDIHIHLKHLPFLEFDPPFYARYLRVENIMTPSPITVKQIVKVREIYEILKTCNHGGFPVVIPPKALTTDDDEAPLTKEQRRHQELRMQKAAKFIGIIQRRHLCVLLQRKDFAIEKPTPFTRKPAGDTTLLYNEHYALSYRDLESMYPRFPTIHDIKLDEDELDLWMDLTPYMNATPHTVQDQTPVPRAFRLFRSLGLRHLVVLNRRHEVRGIVTRKDLTPSHLKSCLEGLSETEKMRIQGYFNRGRSMSERFEDVEKTLLNLRDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRQ8</accession>
    <name>A0A8K1FRQ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_001413</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRQ8"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000004">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW69257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="153" mass="17553" checksum="8168180DD6154782" modified="2022-08-03" version="1">MSTAARRRLMRDFRKLQNDPPSGVSGAPMDNNIMLWQAVIFGPDDTPWEGGTFNLTLEFSEDYPNKAPTVKFITKMFHPNIYNDGQICLDILQNQWSPIYDISAILTSIQSLLCDPNPNSPANSEAARLFQENRREYNRRVREIVEQSWVSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTE9</accession>
    <name>A0A8K1FTE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTE9"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000002">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW69523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="198" mass="22228" checksum="CC2D7AC1A5A85903" modified="2022-08-03" version="1">MMEPRRSTGVATTKLHILDRPLSRGKNEVSLSAFAFLFSEMVQYFQGRVQNINDLETRLDDAGFGVGVRIQELLCQREKAGRRETRLINMLQFVVSTCWKALFGKAADALERSTENEDEYMIHEVEPLTNKFISVPPDLGQLDCAAYIAGMIRGILTSGGFPAQVTAHAVEAGNGQRDKTVFLVKFDEVVMRRERVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C203</accession>
    <name>A0A8K1C203_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C203"/>
    <dbReference type="OrthoDB" id="427735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="49"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW54986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="764" mass="83402" checksum="26631E91D022A982" modified="2022-08-03" version="1">MLTVLVKRIVQSSSERKAVWVLTGGADASSTQLESSLEELYLALKGTVSIYTMDQRGTGKSSPLECEAIDKQVVGAAVDFNAVADCAYSLLSKMDRQPRSYSTSSAAKDVVYLSTSLQTENQEIYVYGSGMGSHLATRVMHLAPKNFKGYVLDGVISEMTKTVAHITSDREAAASQLAALCDNDSTCRSKYGDDLFNVRTMYDAWRTLPTELDVARNACVDLLCGKCKDVKPSDMLRVLLDVGIPMSSKSTLGEIPAVMQRLRRCNEDDANKLRDRLQIPEDKSYYDVWTESRAEREIAFGDARTPSTQMLTQLIKHSELWSNPSPSWDQEQQAIKKSTFGVDQALDYAWHCVLSGNSSDPSCSALEDYGHQLSPSIDFWMISNMKPLLYTEDQYDHNDATIPEGASALIMSGKLDVGDPLSGFDDQHLYMKGDKKRLVLFEGNSHGSGFMSAKPEDHSDCGAMIIASYILAGGDVSHVDESCLSEVPKLEFKTVPLCHPGVCASSKKINVHVKRIVEGNAERKAVWVLTGGADASFPKLESSLEELYLALNDKASIITMDQRGTGKSSPLECEAIDKQASGAAVDFNAVADCAYKLLGKMDGQPHSFSITSAANDVVYVSTPLVSDSQDIFVYGSGMGSFLAARVMHLSPKSFKGYALDRVIGESTGNFAHTSSNREEAATRLAKMGDNDSACRSMYGDDLPDDQTMFDTWRALSAQLDDADNACVDLLCGDCESVAPSDMLRCYWMLAFPLAGHQHAEKSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C231</accession>
    <name>A0A8K1C231_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CobW C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_013791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C231"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="6">
        <location>
            <begin position="244"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="395" mass="44070" checksum="8F748B26167BFEF5" modified="2022-08-03" version="1">MVKTPATTTAPPRMIPVTILTGFLGSGKTTLLNHILTEEHGMKFAIIENEFGEVGVDDALIKQRKYGADEEIVEMNNGCICCTVRGDLIRIIQEILKRDLALDGIIIETTGLADPAPVAQTFFVDETVSARCKLDGIITVVDAKHILQHLLEEKPDGVENESVEQVAFADRVLLNKTDLVTPEEIINIKKEIRKINDTVEIVECQHCKVDPNTLLNIQSFDLDKVLVKEPDFLENTDHQHDTSVSSVGFQMDEAVNLGKLQDWIQELIVNKGNDLLRYKGVINVKGMDARFVFQGVHMLIDGSFTTPWGNETRQSRSVFIGKNLDREQLTAGFLACKAGKLRFKVGDRVRARVHSGFQSGTILKVWDEGNPYRIRLDDGVEVWGSMDTDALVRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C241</accession>
    <name>A0A8K1C241_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_014780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW55009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C241"/>
    <dbReference type="OrthoDB" id="118256at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035450471" description="glucan endo-1,3-beta-D-glucosidase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="11">
        <location>
            <begin position="260"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="10">
        <location>
            <begin position="313"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW55009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="550" mass="58069" checksum="69D187CFC844C694" modified="2022-08-03" version="1">MVKLYTLVLVSALAVSSATKINFVNKCSHEVDLQHSQLATTFKSIAKIAPGATFSHDANGAAHAYRHGSSNAATMAEFSIPSGQPWYDISIIPPMPGNCNSYSNCKAVTKSVGFNVAMNIVPKSNDNGANCRTLKCPSDDPSACSDAYHFPDDVKTHDCPAGTEFDVVFCPNGNAVSASNPEPTPVPTLAPAPVVNPAPVVTPAPVNQSPPTQAPASDAYQPGVVSSGDSTVASDAEVTAVSSGTIKGTYSYKGKYAGNVAGSYDRVTSLNNCQKTKVNVNNPIGPMSEGVSMVFRGPMNIHNVAVFQQTNNKWSRVSSFAQGGNTENMVFMNNKNIDYSGQGKHGPQGLASTDGLSVASKVEQFSGKLIEAKESANIYGGPGIASGAEVNILTGDKCNGQCLGYSGDNDYKGWSGGKKIFVTKVQMPQGTSPNQPAIWMLNDQVVHSNQYGCNCRGMGAAGGCGELDIAEVIETNAARDRVSAHYYFYDGTLNAPNGDNWGARPTNAPTVYVTVMDDSGEGLIKILELSDFDFNSKTISNDLYQQWLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2C2</accession>
    <name>A0A8K1C2C2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RPEL repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2C2"/>
    <dbReference type="OrthoDB" id="197676at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.150.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="46657" checksum="A468E131B43D90E9" modified="2022-08-03" version="1">MAKKAKQQAANGGKNGATAAQVSPVKSNPASPVKVASPQKTQQEPEAAPLKDVAEKVDQALKRRKSIEEVQEAGIIKSPEDAEKMVHLTETMEEKMEARPDQGDMEHIINPTGANRRLSGVLAATAKDLEKNITADKIDRHLHSRPDVDELEKKNVLDTHTAPKLQSVQKKLQRKMSSDELAHRLENRPDVTDLKDHGIVKDGVAPSLQATQDKLQRQLNADRVNHQLVKRPSVGELSAQGVLDKTDVLVAPSLTATAKQLERNLVQNHVAHLLETRPEKDELVTHHILEDPSNAVSPVIQGKKNQLEKQLKVDEVARHLRKRPSVSELEEKGIVDEGELSEGYSNVQKKCSLSRRARYTLALKAASRIAADNLISQDEKARLKDLILSDDEKVVAALECYELDQDIEEMLDTLYRVAKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H6</accession>
    <name>A0A8K1C2H6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2H6"/>
    <dbReference type="OrthoDB" id="2179582at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="491" mass="57054" checksum="4E8136BFC5A53DEB" modified="2022-08-03" version="1">MATSPQRLKREDASSLLDAFAMEPSLVDTILSYVPSTNASDIKKTIANVCLALPTSYRSVLDRVRPSNQAFWRRLVLTSFNFEVDPSKTFNVEDYDGEGAHFYDRDEEIQAIVEEWEQTHGGAQVDEYLLENLAYWQHLEVYFRPSQYGFLRAIQMGELLVDEWPAHEDAFTLFCDLSTLVDEFKAFENLYTFSDGDQFIYPCLLSELQKPLGPRNFELLEHCGIAPHFWEHESPPVWRWAEFGGQAFWRQLVLATFDFEVDLSDTFNVEDYSESSCEYYSEDREVLRAVKKWERANNYAEVEDYLLESLACWEHLEMYFRPSQYGFLRAIQQGELPMDAWPDHEDAFTLFCDLSTLIDEFNAFEDLRTSSDGDQFIYPCLLSEPQKPLGPRNFELLEHCGIAPHFWEHEGPPVWRWAEFGGQVTCDGYIFPLCEDETLPALKALVATKMRDWRAVMVDIPDGEYAAPMFFLGTTKHSQRCLGYVGQRDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2W2</accession>
    <name>A0A8K1C2W2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2W2"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425472" description="carbonic anhydrase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29937" checksum="6144F9BB80E7E813" modified="2022-08-03" version="1">MKIFSLLASVACLGAVVRADGAPQDGQKAWSYKTNDPSVYSPAEWGIANPNCNGKRQSPIDIKTKDLCESEHEAKKLPFEFKGECSEYHLKQLYDAHKAEVMHGSCSVVAKGKEFKFAQVHFHAPAEHTINGKVHDGEVHFVHLADDGNALVVGLFLDAKKDATTPPFLSGFWDRLEGVNTTNAVDFELESFYPLVQDAASRQRVFNYPGSLTAPKCDEIVDWFVVEKPLAISEEDLSNFQSHLKRIEASDDGRTARPTQPLNGRTVLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3G1</accession>
    <name>A0A8K1C3G1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_010597</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="754"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="794"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="867"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="896"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="106"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="427"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="758"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1073"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1313" mass="145310" checksum="55FA09FBE07A63A3" modified="2022-08-03" version="1">MPDPVRSPDDTYAALQSPQIREPSSENESPLDRVHWLSRLTFWWAHGLLARGYKQPLQEDDVWDLPATDRAAILQRTFDRRFHSAPSEGSMRIYRAMWHSTKRTMALAILLHLIIAAATMLQPLLIKSVLEYIQNEQASNLFGLSTGYGAAGLLTVTSFVGVTSLDYGMYLASRAGMNARMIVVSSVYQKLLRLSSMARQTMSSGDIITLASVDSERLYDGFSIGLWAVLSPLIAVTCCILIGVEMGVYVGLVAAACCVCILGYAVVNSRQIGRVRREILQIAAERVKVTNEVLQGIRMIKMYAWEESFSGRVGEIRAREVKLLRKYDYLRVQNLVMLMLAQTFMTAACLLAYVYLGNTLTVSTAFTLLALANACRTPFGRFSYAVVFATEARASLHRIANFLAADEIRSSAVASTSSSSVGNDAIIEFVDADFAWGAPSDSSVPRLALQNINLSVQPGTLTIVVGAVGSGKSSLVSAMLGEMHRIRGTTAVRGSVAYASQQPWIQHNSVRENILFGKPLDQQHYDAVISACQMRRDLDILENGDATEIGERGINLSGGQKARVSLARVMYRRESDVVVLDDPLSALDVHVANAVFFDCVLGLVKSKTRVLVLNAHYHLLPHADRILVMSDGQIVGDGSYAEVRTRFPFLSEAMVTEADDAGNNASTDGGNCREPHDRKYSVVVGPPGSVGSVSLFDRTSRVSNRDRKSRVIGEDDPLPTKPQKALILDEDRALGSVTWRTYISFLELSGWNGALVAAAIFVVFVIGQCGLVGADYFIKYWSDGSLNEFTQSHLLWMYIGIVVAVVLLWIFRAVIFTEICIRSTTATHTRYFHKILVAPINTFFDVTPIGRILNRFSRDLDQIDNPLLYYALGMLMFGTLMLSIFVVCAVTTPTTLILYVPLFGVCYYVQAYFLVSSRELKRLDGITRSPFLNLVGETINGIESIRSFHMTKDFSRKCHELLDNNAKFFFMYQTTTSWFAMRVDWLVTTVVTVVSFTCVASKNSIGSANAGIALTYAVQLSMQFQRVLTLASMTENHMTSFERIAHYASLDEEGDSREVITKPEPAWPQQGHIEFSNVFLRYRDGLEFVLRGVNFTIQPGHKVGVCGRTGSGKSTLMNALFRTVELAQGSIRIDDVDIASISLHALRSKLTIIPQDPVLFSGTLRDNLDPFNDKTDEELFGVLRKVHLMDDVSKWGAGLSHQVTEKGDNLSVGQRQLICIARALLRDSRIIVLDEATANVDQELDRLIQVAVKENFVGRTSLTIAHRLETIADSDRILVMDHGVVAEYDSPSNLLVKPNGIFASLMESTQAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C402</accession>
    <name>A0A8K1C402_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketopantoate reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C402"/>
    <dbReference type="OrthoDB" id="64577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="3">
        <location>
            <begin position="223"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56106.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="445" mass="49115" checksum="A36188369F5D05E6" modified="2022-08-03" version="1">MTTATASSSAPAASTRPRVALLHSNDSTLTREGEQLAKYLGLTLASTGFVTKASVVAVDTHGPAHAEDEIESDTAALRADGVVIRQQQLGKTRYEETKDLRVLTECRIWILCLDTDSTMRSIAMLQKRFPAKDAGKNKKAAKRIILCLQSALRELRELEKAFPQDTVLQGGACFHLTINKHGIIYLLSHGCFFLERLPADKTHALFVLDMLEATGIQVLSRKNIQAMKWGHSMLRLFYYLNALTGQSVHDSLRDRACRLVFLELLHELTTLFHIVTTASDFATGSVDDGDQPKRSKKATWTPDCSACSYLSIHAIMILLPLPNIVFNTVVLKLLDLGLTASTTGHSTIAKDIENNRATEFETEFKDVFALAQRRSIPLPALTALQQTLRSTTDAKQGVPKLQAAAMLSTGTFRSTRESRAVSRTFWIKCIVTVLATVLLIAYLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4I6</accession>
    <name>A0A8K1C4I6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
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        </lineage>
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        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="432829at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15543">
        <property type="entry name" value="PHD_RSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47162:SF10">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 9 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47162">
        <property type="entry name" value="OS02G0192300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="758"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="403"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="863"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1066"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="596"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="686"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="869"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="916"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="936"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="949"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="975"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1079"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1109" mass="118599" checksum="BDD1670F5DBD5CDA" modified="2022-08-03" version="1">MVKRGRPRSATSRSSRVSTPEPVHEQPASTPTRRPRARAGASGLDQLAHASTELTDSQSARAARLARRKDAAIEEEEAVAVAVPASNGKRSARQQDPEPEEKGDDEDKGNGEGDGDANCDGEHAGEDEDWPTPPPKRRRVQSVDPNYVYRLEVELDEMKSRLRKTERLLDRHTFGKTPSKHTAHNSERLDLVQAEIVRLETTMASLVGRTRLTSPENASTGTTAAVESLRAIQDTLAVLQGHLTNPVSFDGLDYHVRPMFDRLWVHGRESAEDDIRSKLAFWKYKALDMKGRVLAALSGTLPPHTAELLQNALDFLSSFSLLEMRLDPDMRESRQKQQTQEAVERLHDKLVELETQRLNAWTRGPLAPTTWNTTDASVSGQTVEPIVEAVATLATVMTETVPSLQPVQPPAPPLPTQRVSRAPKPPPLSMRHGESETDSDVDEPLPTPTRQNASKNPSKTISGSNGQAQDTSVPSEPSANNTTAARQKTIAPMPSISVTPASVAPAASALSVTVGAASPAAEKPVKRASAAPAQESTAATSKQPAKEDRPGRSTISLDEYSRRSKDANVPAAVSPDKRPSQPSVAPKPTKEPTAKDTATPSKQSQQGQRSKPGSSTVSSNSRAPESSGQSGSKRKRTPSPSPPPPSSAEPAARKKSSDVAKKSKSKSSSDVALLKKILESRKERISGTSPASTAAASPASSSSSIQIKAPSKSKAASTDSSVSKKNEEKRQSDNGLLPIPKPAEAQKPSRSRDTTSPSSGCSACKRNDSYASLLLCDNDCGREYHTFCLSPPLSKIPEGDWYCPRCLRREGLRRNDLIFRCSVSNCDKITAAKYCYIHRCQHPEGCLNRTNWRGLCRRHYESRRDKDPTITPIPSPSTDTTPASKNAKPAASTPSPSTTATVSVAKTQPTTASNGKSPSTTTTSEKSQQATPNTTKSKETAKSSDKKSTNSSETPPATTGSTKNQPAVGSAEKATPSTLTTEKLTQPPVSSEKSKQGTTSSAKSKPADGNAATAEDTMTRATKSSMVAGAPRSKSSKEPKSNSEALMDNMRQLGMWMPNNLVSSVVKRVESNPSQRAHSSTTATASTKSSGASTARSSSAPLDPPSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4I9</accession>
    <name>A0A8K1C4I9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA capping enzyme adenylation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4I9"/>
    <dbReference type="OrthoDB" id="200924at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000256">
        <property type="entry name" value="mRNA capping enzyme, C-terminal domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="2">
        <location>
            <begin position="409"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="608" mass="68215" checksum="B649750E4549A7C8" modified="2022-08-03" version="1">MASTPSHAEVAAKLRRASSNGTNGDVDKTPPTRVAKTERKLLHWTPDEWKAFEATPLYTKLVSSARILPIRAPLSSIYEIHFADERANYTPSALMEKLLAQTKAGPMMDVGVVIDATGSDNYLFDPKEWYDWDVKYVKLRTVIPEEADEKTRAEAEEAMTKEFLDELEKHKTSDIKDRDVAVFGATGYNFVGYLIASFLVEACDLSLANALQEFAASTPPGIYSRHYLERLYRKFFSTLPSSASTVKCPAPPKWDASAPSDDAGSKIGNDILTDEDRQNKFVRKDKPRVTVSSQSTGPVTSAASATPTGRSGGLPAGPTYKPPMYIPPDREDINTRPTKRRKIRSWVDDVQPLEYGEALDTASEEHERLSKALEKLTGHEGFPGCEAIPLTATHVASEAFKKRGCLTPSYLVTWRARGRRCMLFIAEGGVYVVSRDMTFTKVNMKFPRRRAPAESQVNTLIDGIIVEDEDHDHKVARYLTFDIVFLEGTPIWQKKLEKRLQCLQNEIILPRKNDQTFDYAKEPFRVRMKDHFRLAKTEFLLSKFVKDVTHEVEGVLFTPTEAPYNLGGFETEDPVFKFVASDGSGIPGLDGSIPQRRLLEYIQTIPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4J7</accession>
    <name>A0A8K1C4J7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4J7"/>
    <dbReference type="OrthoDB" id="128695at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035427938" evidence="2">
        <location>
            <begin position="21"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="487" mass="49018" checksum="B1969CFBC2CEEB10" modified="2022-08-03" version="1">MRSPAQLALFLAALVASASAGQYSGEDSPLHNASPTVTHPCTGTPAPTPAVTSPCSDDVKTPGPESESPSTGATPVPTPAASTPALTPAKTSPSDEPLPTPAASAPESVTPCPSLPQPTPDRIEPTPCPSLPQPGSSDGSETPCVSLPTPTEPSSSTPGPTPAKTTPGASNPVPTPAKTTPSNGGVEPAPTPAKSTPSEAPSPAPTPAKSTPSGGADGSNPAPTPAKTLPKTGVPIPDPTPAKTTPRGHYGPAPTPAKTTGGNKLTPAPTPASTSPSGSVNPVPTPEEPTPSSGTTPSPSPAKTTPGSQTEDPYPTPASTSPRDDDYDPEPYYPSEVEEETPSPSLPQATPEGEEETPCPSLPQRDDDEDTPCPSLPQREEDDTPCPSLPQRSEAEDTPCPTLPQPDADETPCPTLPQPEAETPCPTPASTQSVHALSTSDAAPLRNAKQNDEVKTLEASTQTSSAVQAVAVPALSAFVVSLAYLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4N0</accession>
    <name>A0A8K1C4N0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4N0"/>
    <dbReference type="OrthoDB" id="122811at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="773" mass="86632" checksum="45B6755A96EBCC6B" modified="2022-08-03" version="1">MDKTPPSSQSSQTADAASVDYTLLQRLRQLVRYEYANSEAPSDDELLAALLQCHNHLHDAYHLLKRRRVAAQEAADLAATDFDVDVNMQVGNGAKRSFHEVDGSEALSQDGGHKRPARSLGLSTDFGRDATLVPYAMTQGTQFSQSSQLTQMSQSSANRVDLTADETQARQVLTNIVDDLVHNRPLRDAQWVPTVFTALCLTVDDDLQQAVEAVTRAVAKALEYTSEMDQLNLKRQSVDAIMEVLLRLPHDGESYLPDDVEPTDEELDRLGLHGETVYQEATAASGTMHSRSEAAKTAIEALRTTCESCIRRFEWFSTAGRKARASRNQQREQLQQLVSRVDEQLRQSKLDVEASEHHMNDALKGSVERTMALQGIVDRRRDTYVESGAIPVVALFKANVEIIQSTDPEVVSLLNAWNDSNHVVESAKRDVIGANARLEFQQKLRVLLEKTSQRREWWLQSTSERLNEARRASEARVTQQLRGCVPRLTHALRLYYDFHSLRQRKAQSDRAAQEEALRAHQEFYEDLVPTQRDDIIKRISEYNGVILRSTQLMREAATAQSNLWAGKRDVLPREVLDLVLREYQQLWQSLDGGGKEMMRDCVSQIQGPSHGDAQDVVAIKTEPVSPVISSSATPQNRSSPTIVDLTGDQPAPEPPIRSSPPKNQHIESPYRVGDSLAVVPAAPHPSELPLVTHEYPVGAILYTKMAVRDRGPRFFRGQVDALLPDGTYKMVYEDGEVFVVARPYIFTEEQMREEMLAEGGDDDDGDNNRCAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C542</accession>
    <name>A0A8K1C542_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C542"/>
    <dbReference type="SMR" id="A0A8K1C542"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000158">
        <property type="entry name" value="Polyubiquitin 5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="25818" checksum="7E6164A72199CEA3" modified="2022-08-03" version="1">MQIFVKTLTGKTITLDVEPSDSIDNVKQKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIDNVKQKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIDNVKQKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5H0</accession>
    <name>A0A8K1C5H0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_002812</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Galactose-binding domain-like"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22633">
        <property type="entry name" value="F5_F8_type_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
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        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="15">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="347"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="1185"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="1221"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="1272"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="1302"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="10">
        <location>
            <begin position="1943"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="10">
        <location>
            <begin position="2001"/>
            <end position="2057"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="10">
        <location>
            <begin position="2058"/>
            <end position="2113"/>
        </location>
    </feature>
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        <location>
            <begin position="202"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="459"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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            <end position="1563"/>
        </location>
    </feature>
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        <location>
            <begin position="2496"/>
            <end position="2534"/>
        </location>
    </feature>
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        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
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        <location>
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            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
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            <end position="538"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
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    </feature>
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        <location>
            <begin position="705"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
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            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1019"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1038"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1058"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
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            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
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            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
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            <end position="2521"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW56887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2597" mass="285830" checksum="9401563AECC605C5" modified="2022-08-03" version="1">MSIHFKFKSAKEFDTVTFPGAVIRVLDLKKAIVDKKKLAKGLDFDLVITDAQNGKVYDDENMQLPRNTSVTVKRIPSLQPGSGLLARMKAEAAAAAAAAATAAAVPALAASPVLPLGVPQGNIPSAPLMVVADSSQVKQGEGAQTMEDELAALQSIHEQAEDMRGARLGNKTWTASSGSNADKVANYYAGIPSGAGAAGGRGFNPMGGRGPMGGRGPGDGGMAGRGRGGPMGAGVHPSMMGKPPPSYVCFRCGTPGHFIQNCPTNGDPEFDHHRVKRRTGIPKSFMKAVSDPSEIPVGAGKTVVNAPWGGLAVIETQNKNFSKLMTKSGGSATLDQLISNPPDHLACPLCKRLMNDAVLIPCCQESACDECLRSALIDHNLTCPLCNTPNMSPEKLLPNKVLRASVEEFLRRARTEQQEREQLVKEAEEKAMAKQKAAEMAATTARRAAESADATLEIKKGGKKDGDDDEDEFGGDIFGSADEVDDLNNSRKALSAQSSPAHPPGLSSVPPPIPPLPPTDSSAGASALPSGSAPPADGVEATNGEDDVESKSGEPSATGDGSSVGQQPPGFPGGPGGQWPMGPPRGPPGPMGFGPPEPWFDGPRPPGPWFDGPPPPWFDGPFPPGGPPRGPAGGRGRGPPPGYFGPPPGHPDYFGPPPGHPDYFGPPMPWFDGPAPPFGGGRGGPGGWFDDERGFPPRGSRPRSNSRDGKDGSRENSETVEKDGHKDGRKKRSTSRAADRKRSRSRSRSRGDNHSRKSRGGRSRSRSYSRSRKRSSDRDRPSRASSRSRRSRSASRDRKRERKNGDNEKERIAKPSDERRSGETTQSEPVSKAKDVQLDQVAAPAIDLDFLEDHPDNQSDGEKEKDAIEESRERRVDSGRQTPRDDDGGYAKKALSTWKSEASVVSRKRSTSPRRKSSERDGSAERRSKGGSGRSSRRSRSRSRSRRRSSESKKRSASSGGRDKDRDRERGRDKDRERRDRDRDRDRERNKDRKDKESKRSRDDDEEEGRGSERKRRRSVDGDRGRDGDKGSSGRIVVTTSSRSKQATSGQNGGRGGRKIEFDGESDRKRSGRKKGDDSRSSKSSSSAFGDHHQTKKRSVLDRLGPAFRRKRPSLTRVAEGGSSEPTGATKSASDGLALFGADSDESDDEATIERYANGSAEKDGGEEKEAGAVDAERRKVSILLSKLTPEELFKRYDTDGSGSISISEFLAMLPDLGIRMSEAKAIRVFKKCDTDGGGAIDLNEFKMAMFAVDPVSGNTQGFTPSQFLSPKDAFGLFDEDGTGQIDELEFADVLEYFGMDVSDAKQEALFKKYDKDKSGYIDYKEFRSVWLRLTNVREELTKRGVEIPKYTTPWRLQQMLEEILDVEEAREAQVLAEAQRFLQQQREQQKRAELGRRAIIRAQDELAAALDAAGQVYVLGAGKYEQFAGQAVPRDEDLFPGFRAVSAIWSYRVDPQVVSQPTTTHPMTDPEQQQQSPAPMEKRSQNVLMVPASAQRKSDRYVRRRPENCRWTFRSPPKLNHQTLNSLKREIKAVHAIMAGADDREEETLDSSVRDPEPQDAPVERTILPSDEEELARLFYQDRERVRSLRFRSTVLMKNTGSLWGRGVVQGAVSDDVAFAVTSAGAVFTWGGKTNTWERGVRRVSFDDNLDDEVHSEKAGRNDRIDGDITVEPRVNHDTDSDGAKATPRSMLVKMATKEQLKGLDNPELESREEESLEADIWQREEDGWYERLKAVVVYYEAWEPPPSNATRVHFLEQVLLPKLVYETMIESMTWRGVPVERATKMELMLQLGECLQLESEFVGMSGQIAFKTQENSIRRYLFSKDKREKSLVEEEKQKLREMWAELKRIREERHAQIYKDKQDKERERINRMDASFEAIAARRLVQREDLVPEFTTRGGNAKIDLSGITSRGPSLHSPRGRVATASIAAGGAHVALLLQDGSVYTWGIGSTGRLGHSRDRSSSVSFDSDHPQLVDAFRDVRIRQLACAFSHSGAVSDDGELYMWGSTTNGKLGVGVVEDCFEQNTVVPLTVKFPGKRHVRSVSCGAAHSGAVTTNGEVFMWGCANGGRLGLGPHVKDAVAVPTIVRDFVTRKLRVWQVACGHSHSALCTEIISEQRGGSKKLLGGQVFVCGGAIPLGRYVTSWESVPALQDVGIRQISCGATHTAAVSAYGELYTWGRNDKGCTGHNRERGFIQEPELVRSLHVEPYNLALGKPCRQINIYNEQGPQLAVNGDVDGRLEKCIHTHLEEKPWWEVDLGQPAVIERIRVWNRTDEPTNPSKSRSEYTVRLFPFWILISEFPFKDLEGKEGLRAAKTQSAAFEQFTCNQRMTEWVLPTAHTVGQYVRIQLQSRNFLHLAEVEVFGVYSAFNYVGRVGTAHCGNEATLVIVPPTHQQSALDDYYLRAIQADADHATILRQYEAYERSYRLFGRGNSQVLGAKCRLCRVFRECEICEFYSNADIDRFRSDRGELPSRLVGDRLGLNDLVKLAVEELEDDRTRTPAPTTSELVGSNVDPQQSTVVADSGNPKIQEDLPARPPIVEGEAALEEKPQIQEQPQQLQQKQELSPAPVATVCKLLPSLKHLVSMLPFARRKGAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6F4</accession>
    <name>A0A8K1C6F4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Methionine synthase</fullName>
            <ecNumber evidence="5 16">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Poli38472_003125</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 19">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16 17">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="16">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="5 16"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="261426at2759"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00740">
        <property type="entry name" value="MeTr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1240.10:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000002">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.330:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.280:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.280">
        <property type="entry name" value="Cobalamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.288.10">
        <property type="entry name" value="Cobalamin-dependent Methionine Synthase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="entry name" value="Vitamin B12-dependent methionine synthase, activation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050554">
        <property type="entry name" value="Met_Synthase/Corrinoid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007024">
        <property type="entry name" value="PRK09490.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833:SF1">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="Cobalamin (vitamin B12)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="Methionine synthase activation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 16 17" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="15 16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="21" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 16 20" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16 18" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9 16 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 16 17" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="22">
        <location>
            <begin position="27"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="23">
        <location>
            <begin position="381"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="26">
        <location>
            <begin position="681"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="25">
        <location>
            <begin position="795"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="24">
        <location>
            <begin position="950"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="923"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="725"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="805"/>
            <end position="809"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="808"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="853"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="857"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="912"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1001"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="1249"/>
            <end position="1250"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="TMW57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1287" mass="143563" checksum="C33755376DF4CB4C" modified="2022-08-03" version="1">MSARAEVTPMETAMLQQPFVRGETDIFAYLTALMKQRILIFDGGMGTMIQQHKLTEEDFRGERFKDFPMLVKGNNDLLSITRPDIIKDIHREYMEVGLAQLIGTNTFSGTTIAQADYKMEHLVYELNYESAKIAREVADEVTAKDPLKPRFVAGSIGPTNRTLSISPNVEDPGFRNVTFDELVAAYYQQVEGLVDGGSDILLVETIFDTLNAKAAVYAIDQYQENTGRRLPLFISGTIVDMSGRTLSGQTTEAFYVSLRHSKPFCIGLNCALGANQMKPFLQRLSNVAECFVSVYANAGLPNAMGGYDDSPQLMADHCEEFCKDYLINMMGGCCGTTPKHIRAMAEMTMNYTARPLPPLKDPFMWLSGLEDLVVTKERFSFLNIGERCNISGSIRFKKLILKGDYGTAMDIARQQVEDGAMVIDVNVDDGMLDGVAAMERFLNIAVTEPDVSKVPFMIDSSKFHIVEAGLKCVQGKCIVNSISLKVGEELFCEHARIVKRHGAAVVVMAFDEEGQAATEEEKIRICKRSYDILVEKVGFPPEDIIFDPNILTIATGMEEHNNYGVDFINATRRIKEVCPYAKISGGVSNLSFGFRGVNVIREAIHSVFLYHAVAAGMDMGIVNAGMLEVYDDIPKDLLKLVEDVVLNRHDGATEALLDRSLIEKEKLEAAKKGGVDPNAGIQQEWRTKPIGERLTHALVKGISEFIDQDVEEMRKACARPLDVIEGPLMDGMNVVGDLFGSGKMFLPQVIKSARVMKKAVAYLLPFMEEEKAKSRLAAAANGEVLEEEDDDSQYAGKVLMATVKGDVHDIGKNIVGVVLGCNNYKIIDMGVMVPCEDILRVAKEEKVDIIGLSGLITPSLDEMVHVAREMNKAGLKIPLMVGGATTSKMHAAVKIAPHYSTADHPVIHVLDASRSVVVVGNLLREDEEREDFVEDLLEEYEELREEYYASLDDIKMISFADAKKKAFQIDFENNPPFQKVNRLGTHLIEHLDLEKLVPFIDWNPFFQTWELRGRYPNRGYPKIFDDESVGEEARKVFDEGQKLLKEIISKKLMHVKGVSGIFPAYREGEDVIVCDPSNPDTPVSKFCMLRQQAEKETSDPYMSLADFVAPRRAGTYDYIGGFAVGVFGVEELAAKFESEHDDFNKIMSQAIGDRLAEAFAEYIHREMRVNDWGYAAEEVLDKEDLLKVKYDGIRPAPGYPSQPDHTEKRVLWELLKAEELAGLTLTDSYMMLPGSAVSALCFAHPESQYFAVGKVSKEQVVEYAERKNQTIEETEKWLAPILGYDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6J4</accession>
    <name>A0A8K1C6J4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003185</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6J4"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000009">
        <property type="entry name" value="Probable E3 ubiquitin-protein ligase HECTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="12">
        <location>
            <begin position="427"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="220"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="245"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW57260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="773" mass="86720" checksum="87742CA4A92DFFC9" modified="2022-08-03" version="1">MTTLSTRRSLWTALGRFLLWGSCRLVLIAAWTSEFALSPLPPSPSPPSFRGAATDSSSQLDAVAAPETPAGTRPRAKTQVKSDNVEVSLVLLAFVLLLGIGALCSLYSVCRQVKCESDEPHRIGRSGSRSGSSSFQAMLTRSPNYFREDLLNEDELLRLWICVYCDFANYEMKTQCALCGNEKEEKEIPTTPRSRAQTIRPASLFASMATTISSSARSFSPSFLNIGSPRTDPDQPTTAPPSPAPSSSSEQEPSSPRMHSSSSSSTPPSPSARSTATVKRRKEWQSVLDPRTGNIVWEHCARHNDEEDGIPDALITQTAFVSHNTISPEHPHGKIEFVAAPGATVYGSSRPEYYNLDSEYLFLDPSAIETLRELSFPEKHRWFMQETTSLLHVRWENPTMTTKNDMNLLVPRENLFHGTMHALIDVSQKQLRRPLRVRFLNEPGIDAGGIVREWFGLVINEFLDEKNGLFQVVHSSEGEGLAYTIHPMASVAVPDHLLYFRAFGRLLGKALLEGHLINVPLADFLLKHLLSVPVSFVDLHTLDGRLAKSLQMLSDTILEDVTDDDDDPYALDFTIYHTALGVVELKPNGRDLVVNEENKQEYVELFTRWHLGEAMREEIAALVSGLYDVLPVHLLAPFDYHELRLLLCGSPSIDVDDWEQHTFVLGKRSTKSARMIQWFWRIVRSFTTEEQMRLLQYATGSARVPVQGFKALTSSDGRLCPFTLFCLPKDECVFIRAYTCFNRLDLPIYKKEKDLEEALRFILLMDVTGFSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C776</accession>
    <name>A0A8K1C776_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013368</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C776"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="298"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="555" mass="63124" checksum="823F95EC9CD539F6" modified="2022-08-03" version="1">MSSTAIEFGLINTLRTNHVLVDAFLCMLVPLLIQRVMNAVQTSQTSLWTLICNIVLRRDDTAYVNRVIEFTQKFNRYGTVWDNEQQNDVLQKAVSIYLSEMIDLRNKTARCELIEKPKKKAKTLDDDNDDTHSMTSMSSTEDEEDNRCEVEKLNVEELPPFQEWIEVADGVEFMHEVVSSGETDDKLTVKESKVVFRFRSAREDGATRIDELVQNAFAAYRAKERAKHKSDKSRYFYIQNGGSDSMASSNAVVTYKRYALSEEKTFDNLFFDEKTNVMQLLDHFMKKTGKFAIRGFPYKLGFLLHGPPGTGKTSLIKAIAQHTKRHIVTINLSKIRTNQELLDAVFDLKFTVEGMDYPVPLTFEDVVFVMEDIDAASRVVQTREEKPTFVRSESSVERMVESQKKAKQIDDAEKAGDEELMPSLMGPALKPKETDKLNLSGLLNVLDGVIDCPGRIVIMTTNHPEKLDPALIRPGRVNKMLLLTHMNATQCQHMIEYYCMEKLTEKQSERLQAIYNVASRTFTPAEIEEYCAEHDDADSILDAIEAHADVAADAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7J6</accession>
    <name>A0A8K1C7J6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7J6"/>
    <dbReference type="OrthoDB" id="148089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="44207" checksum="DD5D6A8EDC9C8565" modified="2022-08-03" version="1">MKSQEEALLPSLSPVVGPLSKEEKQARQRLHVKRTYYRKLHRLQGLRSQLEQLETQCRQLVEQKTLQEACALIAGLPDFEGLRPAVKNKDEELTLMKCQLEQQNEALRIALREYESSEKMMQSFINLRGDTEESDEEEEQEVTTHFAQLAVLTRDVKMRVVVPKLKAPVTLELCRQVAEQTAREMHVFRASPHFVTTGVSVLGWRDRRLLGDSQVQFFLEKTFHGISARQFLCRGWVYMSSPQKHPLLYSTSIRPHMFTIQRVDDDNLILLRVFSSPDGSSQVKAMFLVSRFKIRTGYAVIQRSLDPELMAPYETPTDVYEQWADVYTWVMFETAGENNEHCKFSFGGRVQSSVAVGSDAWMLEVLFIGVRIESLVVGPLFTLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7T2</accession>
    <name>A0A8K1C7T2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7T2"/>
    <dbReference type="OrthoDB" id="77399at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="296" mass="32710" checksum="92F93502F5BEAF2E" modified="2022-08-03" version="1">MLAVTTHGEAPGMETLTSRGSLSDLSMRNLFTADEEDDDLMALPTVTELLVEVGRLQLEVGQLGPANADLDADIESLDGSENSMTMVGRRPRLRSDPRLPVGLTRADLNASFSSDNGVLPKRRSTSNMSARMLSTVPRVAALTKENISLLRAPSDRRNYAGSVAGSQQSRTSVRTDGGAVFSRLYQPDFYKQRDAKLKSLKDRQEINFSFLPRTNHRSSISSRDSIGSSSVSSMRSTNTDVLNVSSRLYDPEYMRKRTAKLQRMREEREMRNCTFTPTINRKATPTTTPAATPSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C847</accession>
    <name>A0A8K1C847_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011739</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10060824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056343">
        <property type="entry name" value="CFAP47_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053879">
        <property type="entry name" value="HYDIN_VesB_CFA65-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058952">
        <property type="entry name" value="Ig_CFAP47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45912">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45912:SF3">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24529">
        <property type="entry name" value="CFAP47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22544">
        <property type="entry name" value="HYDIN_VesB_CFA65-like_Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26579">
        <property type="entry name" value="Ig_CFAP47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HYDIN/VesB/CFA65-like Ig-like" evidence="7">
        <location>
            <begin position="449"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Cilia- and flagella-associated protein 47" evidence="8">
        <location>
            <begin position="1625"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="domain" description="CFAP47-like immunoglobulin-like" evidence="9">
        <location>
            <begin position="3049"/>
            <end position="3170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="916"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1682"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1827"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2188"/>
            <end position="2211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2411"/>
            <end position="2465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2869"/>
            <end position="2891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3295"/>
            <end position="3329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1694"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2188"/>
            <end position="2198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2425"/>
            <end position="2454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="3296"/>
            <end position="3314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3329" mass="363426" checksum="DD2EEF299DD940BB" modified="2022-08-03" version="1">MEPLAASSLLRPATPSMAMRTTSLLHVAPTVVEFFAFEFHHEYVANLVVRNASDRALRFRLVPPAPASPFKVLYQGQDLATTSNPTLMLPSGLSIKYEVVFSPPTPQNEAESRSIEHAIVHDALQLRGDDGSWVEVPLVARKAFPEFVVEPSLCEVGLVVLTHRAASLVRVKNVGARPGRFDLEVLDPLSDNGLSQWITVMPTRGVLMAQEELTLKVDVLGKDVGVVRGVIRLRIREADASDQEEEDEENQDALEDTPATLSLQQLHGAYCVEKLIDVCATVMEHTVEFLQSHGQNKVQQLFFGSLFAGEVKTIETILRNNGPQPLFFKTNLTFSGQQTRLDSGVPSPVNGQSDDEREAYERRKELQVYPAEGRVEPFSELLVTFTYRPRAIDWLTLQHMERKQQQAPETLDANDGAGMTQLTAFASILCADLQSQNLTVEVAGKTYLPRVSLTPTSLDFGDIKSHDRVDMLLSLKNLSGLPVAYVIPRVAQFATKPSSGRLDVFQSQAIVVSFVPTQLGSYKTTLEVIIQDGVLTIPLMVKGTAAALGDKSKHDLVGGLMALPQDFEPKYKFVRPEDPKHTKGTLTKPFHRMPPYELAALNGTAAIDEYEFQGTNNTHLTYCVKELAKRADHNAQYHAYLKAQSDKREMVRKKTSAASLKETVSVLRTVSNNNSEDGEAMEMIEDVDMNLGMGKQSGVTPRGLSMPRALKTQQDPLWLDTNAMFSQNPSKKLVFDANKFAKKKFKASPATQAELADCSLSLSFQDLEQIVCGPKTLHFGTLSVNGAAKKSLSVMNALNQNILVALQLQDCEELSQKTALASQVVPPKTLAGFDLVFCSPKEQFFQKPLTVTINGVHTRVVTIVAEVAPIIVALSTQELRFAFSSTDTNASMSLDVSITNPSDSVAPFQWHLLPPSRPNAGAVRPDSSKSSATETSKTSKGDKGQHQAPPQAIYEVVPTSGTLQAGETVRCQVVYTPPSTLAPPDKALYAIAPLYDGEHAASHGNWLVNAFELGIVGGKSMQLTCKGLYQDAKYQLKDKKIDFGTVSVGMHREKHVTLMNTNTLEDGVASRLVFYASIEPATHTHSLGLSVSPAIGSILPQDSCELSVQIAPHKPQNLDNVFLHVQIRGGKSAKLPLLASIVIPEVSITQSVVDYGDVILGVTVSRQLSFENKSNIPACLVLDLTTTPLNKEFTVSMVNSKKKKNAIYHQDDEDLSTIFTPLLPESTDPENGEEDVATGCGKWQICLPASATVSCMLTFTPSAPGSYDVVLPVQFAGLLSAATARPESITRRVQAKAVAPRVRFSSAMLDFDRCVITREGIRKVPYTKTLVLTNTDQSTVKWQIDTTKLKASTVAAAVFAVTSKRASPIAGSASSSAIIFHVAPERGELAPGEEIKVRVSFLPLEPVEYSEDELPLLLDDAFYLHLRLRGVGMHPQLSFSTNKLVLPTVPLGLPSTGRFTIFSTGYDHLEVNFRLPLDVSKAPLTLHFPQGKIVSMACPQIPCEVRFLSKRSVAFHARIEFFDADGNVFHLPIAGCAENCLLTNYTFVDRQSNVETPESLVFYTHPSHLAPIYLLTNKQSQNEIAKAKQKLAVAGSAPPQAPTPGHGLVDVDANGFAGYSEETSQRRPQSREVQFLLQYLNANFLRSPVTHFPQDFAETLGKPLYELLEMVCVKKPPTSAMVGAPPAKPKGGTKATTNPGAATTPSTKERQTQYSTQYGELLKFLKSYGAMLHDVVPEHLLPQELYVRACEDPRADPSILSPVGLSSASSSFLLRRRVLQREWEGVSARAWMAVLYQVIKCFLLFRVTQKSYQQQLQTLMMDDSTSAPVLPAPPAASKATKAPTDRNARTSVASTPAPPVVSPLRVCQGSNVYSEAEMVLLQWLCYHVRRVVHDKRTSGHSSSSYVPESQLLHVPDDLVDGKMLFHVLASHIPTLSIDSSEYRCFRLDTKPGKAPLTPNQLLQQATTLVHAMRCFGVDFGADSSDDKAVSLVTALNAREMVILMLHLYQMLPQFLPKATIEFKGMLGQTIDKTIELKNPSAKLIRYQVFLDTSASSSSSSSHASIETVSSVASEFSIPSNEVVLEPGQIVAFLVRCTPRFSRKATARLVFQSTRDMASSMSSSSSTGATMVFLLESHITSRQPARVITIEAATYEKKTVDVVIENQFLANATYKLTIAQANTTVAGSTSTSLTPSVSGTVGGGGQGRKATKDSVVNRRISSSNSVPTKHETKSEPISAEHAWCIVAQQPFYLPEFGQSVSEIGANNTSVVSLRSQASSTIKVEFLSLVPGTFKCQLLFLDEKVGEFLYEIHATAHLPVTIETLEFQCELQPGAGGSRASTSSHFFKELTVPPKNLQLNKALTTFVDRASGVFKSKLKDGLKKCEETHHTRFAVEFNSPFFTPVASEVTMSLRTPSSTKGPVKASTMASGIGDTSSITPLTSRTDPNSIEMTQPARSDKPSGKANQFARLSTPRGSHTNSTTGFSLSPNVVLIDFQPKNAGVYTCKLLLRSVHTPCVSADWRVYELIAKVKEPNVRTFLDFVAPARHSIVQEIPLSNPSDTAWTLKAMFNPSGGSFSGPSSLSVPAKKLATYPLTFAPKWIIQETTNFVLINPSTQQQFEFELRGTGEEPLAQDHVVLECQARTSLTHVFDVVSNKTDPSGPQVYQVESDLRDVVGASTITVPHPGASAQYALTFSPLVSGTYFGSITFTNLQTKEYHWYTIEATVAPPAPETTLEMHTPVRSVLGVEISLENPLDHTVQFDIELQGRGLLGPSQLTLDAKQSGVYELVYAPLHVTKDDEDGAILFSNSEIGQFWYRLQLRAQEPEPIALDDMSCVVGDVCTQPILLQNPSDQDLSLQYRVTNARNFSIKGDAASSPTHKGGGGGSPSSRSVVRLPPFGNASVVVEYTPSSLSEFEASQVVFYMPGVVSDWTFFVRGKGQAPSLMKPILVQAKVHEAASTLFTFKNPFVDALRLEVQLVLTNGDERQGSTSKSVFDILLKKPRVSLEGFASLQVPISFLPQYVCEARAEIVLRGQDEYAELEWRYPIRGIAEAPLHPKAFVLVCPARDSTEKIIQCELLAAPPGLRLENETITTEWEIDSARFGALATSDAIQRAVMIRPEPVDTQSVSSPRLMIPYRLQFDPLRPYRGSIYLLLNKKSGGRWRFEVVLDVSDPPVDDVLTIESTLNQTSSISFQLRNQFREAAPFQAEFSAGSSSAFTVYPAQGILPAYGSPQGMNFVVSFTPTGYGKMQSGQLLIYTEEMQWTFNVKGTYPDLSASIASKSLSSSASRTRLGIDSVSSTTSQSLISSSNTSSGGSRGGKATSGGAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8K3</accession>
    <name>A0A8K1C8K3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat-containing domain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8K3"/>
    <dbReference type="OrthoDB" id="94960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="799" mass="91354" checksum="5AA811212B278B5F" modified="2022-08-03" version="1">MTTKIAAFVALAEEGWFLRQFVPLLTHEDAICLVLMATESGFASFRHALLYNALPIAPISTQELLDYVAEPGWWSLLAVLPRDGQAKQRKNELLTPSDFDATPLVQCQRIQRHCAHKFSPDVMYAAVRRGVLEEVKWLDGCTEYAAENAALFAAEARHLDVVQWILDQCKHVMYGFQTLLRQEDSALSMICWKFHGSVYCASAEEGLFPSQPSTSTGDQYPLLDVVAKRGDLELLRRVHNDPIGATMCTFRAMCNAAGQGHVAVMQWLHEHRSEHRDKVTEVLTAAAEGDQAAAMEWLHQHYELKDSVAAAYKKTIRSRKFNAMRWLIEHFRSVVSRLEPVRLHEVSSAPLDVIQMCLDVHGLSAGLPFMCAALRCGNSKVARWVAGEDNEQMTLTQVTGEALHCAAVEGGNLELVRWCVEELSAWSDDAIRQAPLKGDISLVKYLCEETLERLRLSNITSDEQDQQLQSIGDEVLVSAVRSGSLQLVRWCIEYLEAWNIAAFKWAKWRKNTSILEYLVTTAHERAGTDDSVVGEMNQVLNRDILVDLFNFRAPKTEIIELILKNCPRSEHDTLARPLFRSSWYPSHRPWRTFRKMLQYQPLHFLRIYKMPQWTVRYGSVDDLLRLEAIKHPELLTKKTLESILEFSRDESVMSWFLARCDWSMIGFRVIDWAAKYNCIQLLELLKNAMMSGQAQRLTFDKDNFQIKFMGTVIWSAIKNDQVAVLDWVNRQGHPDQVKERMWRFSLASSAARHGRLVSVLWLQENSKVSGDKMQELMEISARYGQLQCLQGLIRRFQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB40</accession>
    <name>A0A8K1CB40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB40"/>
    <dbReference type="OrthoDB" id="21124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS N-terminal" evidence="5">
        <location>
            <begin position="427"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="575"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="71882" checksum="E30423107E1EF02B" modified="2022-08-03" version="1">MELPELKGYLRKKSRQDRWQRRYFEATTHYLTYYKNRDSEKLLACIDLWRTQNIDLNPHDADKLEFSIQIGDQSYLLKAENADDAMRWVKGLRGRQSRPDGAPSETFSMRSERFDRESDASSDIGGRRPGYASSDTGSVGSTTKSRVQTHRASFTDSSMNPIVPNADAIAAGRYPMLKTDQQVRKYSNDPDESKMDEEEKKKRSINEMFGDDDSDDDDQIRPVSSNTTADASGLFGSDSESDEEEERKPRKKVAPPPSKKAKAASSSSSAKKQRRADKPAKPAPRRGSGDEYDSGDEIVRTKDDDAFIDQDDDLEDVLGEYDEDDQKFEDERPLPEDVGGRKEEDYFEETLKSLKTGRRAKMNLSVQEQEQIVQEVLYRMDKAHADDLASIAERKPALERIKYVDHAIRVLRKQQLQPTFLDFDLLSFIKKWIQPLEDGTLPNLGVRTKMLHMVARLPVMKEHLKRSGFGKVVMMLWKHPEETRDNKDLCRDLIERWSRAVFDKTLDYSKLAELEAEKAENMGYRRPERRQQQKPAVSRSEYGANPFSGRTSEPKDGPVTERAILPSQLRVDFLHRPQPKVDVQTAASMKVENNADTRKSRLSKRMLEIARPGRKSKRSVNLSIEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB64</accession>
    <name>A0A8K1CB64_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB64"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="206" mass="22287" checksum="7FB5ECD97C2465B0" modified="2022-08-03" version="1">MQRNKTLSFYFQTAFPTQPTIAILVTFQPAGNPDTRIDIRPAGETSQLLPRQEEAVPRRPVIEFLADIGLALAVILFIRTIERPSPQEPEPEPPYWLWTMLLTALLVLSIAAVVFWFTYFGGNMIDEAFVVLGVTSIAINAASECSTACHIPSSWIDLISGSASVFKAAAAISAVVIAGNKFQKGSIDTSAKGKNLLEAVSNTTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBD0</accession>
    <name>A0A8K1CBD0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBD0"/>
    <dbReference type="OrthoDB" id="153128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="20906" checksum="254C758929BE19C9" modified="2022-08-03" version="1">MSTTTAKQDQDLDNVLFSEQKDQKVQKEEQPASTQAPVRRTSTDEESRPQQSSDDEAPANGRKSLKFDRSSIVNAIPVDKIKNGASTAGKVLGNAFSAVKDKTASAYDTAKNSNAGTAIAGGINRVTTAGSEQINKVKETDAYKKAASTASAQYEKTTVVASVALEKAKSTASVGFEKAKSGAAAGVETIKSKVGTGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCV2</accession>
    <name>A0A8K1CCV2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Paladin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCV2"/>
    <dbReference type="OrthoDB" id="66369at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14496">
        <property type="entry name" value="PTP_paladin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14566">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01301">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="915" mass="105082" checksum="4840AC9DFD08F2C9" modified="2022-08-03" version="1">MDTKMEEVDALLASVAAQAQRVKDANDPQYELKELLEPVRSLIVQILAEKDGPHASGSVDPSRIKAHHDQSEAATKIQALVRGTTQRGQLKRQISFHLQGTKVLNNYVLKRDRFPNCHVLDTPDGDHAPNFRRLDGAPLYGCAQPTMQGIQQILQRVADDGFTNVVWINLREEAVIYVDGTPYTARRSAKLNENDLVPGITGHTVQVLETSMKKSLQEQLALSDERFEYWHEVALHDNVLKTLTVDPATVHTLPELYELEAVNQAGHQLKSIRYYRIPIERENAPEHTDLERLMTLMNGATSDTAFVFNCQMGKRRTTTALVIASLIWQLPHLVVHGTGTPRSSPRGRSTSVNGDFAVIRELEMRLRFGKDAKAWVDKTIDQCSAICNIRTVIHEYHESSTSEAKPAKRTYYLHHALSFLERYFYLIVFGAYLLYIKQQHNQLVSTGKKAHPGADAQSFSKWLQHHPNLFRLLDDLGGVKYKSDKILQSSVLKFDHFIGIARIPFELTTNVPNYRQIADEPIFGSAQCLEDGIRDIAQHCLRNGFERAICINLREEAVIYVSGRPFVIRHPDRLMENVEYPGIEVSEIMDIEHKVKEEIQSRVQRANGLFMFWHEPVEFKNEEKIEHINPHQDIKTLNEIYEEVAEESGFDLRYARIPVSDETAPEEKDLDDMVRLLLPAFTEEFGLEIREDQVTASEEVSAQKRTAVFCNCQMGRGRTTTALVCIFMIRLALHDVRVRALDSNEQPSSTLERVLEIDNSPEETRRQSSSVKGDFLVIRKLCETLSNGPEAKRLVDYAVDKCEHLQNLRECIAQCRNLAMDRELSSAKHDTYMLRAVNYLERYFYLICFASYVLEERVHLFQRTLFVTWMNERYGSALYALLDNLFFEEDVGAEIHVSSMRWRWRRKRKLISRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD45</accession>
    <name>A0A8K1CD45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000758</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD45"/>
    <dbReference type="OrthoDB" id="515887at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="233"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="50464" checksum="1EB9955678FAD713" modified="2022-08-03" version="1">MMLVYEISHTHIFAAKHKFAMSAWLQFMIDGGESPRLVPLKLLYLIHYAAFSTQTFLPMYFDTTEHYSKFQIGVLLAIPCVCSIVGPVVWGAAADLLHNQKLVHIVCLVSAALLMFMLQYVESFELMCLMFFLANFQTQPTWSLLDQVAMEMLDSVGGDYGKQRLYGAIGYGIGGYMSGVIAGAVGIKWCFNMVVALSVVSLYILVRHIPSTKRSQTDVDFWGSLKHILQLRDVLTLFVLVLVIGIMAQLIDSFLFLYLFNLAGNNSNLVGIVIAVETTSELPLFFHANKIIDRLGTPKVIFLGIMAYCIRLMTYTMLYNPWLVLPVEILHGVTFGLVWAAFTNYVYQSAPQGTEGTMIGLLAAVQKGVGGGAGTLAGGFIYQEFGPRVMWGSALVFVLPMALIVTITFSFIAKNRRSLVADKLVELEEQPFLKNRSPLYGAIHHLGSSGCLQDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD79</accession>
    <name>A0A8K1CD79_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_000803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD79"/>
    <dbReference type="OrthoDB" id="106185at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="19404" checksum="173AD05B080566AF" modified="2022-08-03" version="1">MSTTKLIFYTAGTGGGPTNATYWLDTTYTRTHGSPSAEMVLLIEYYEVIIPIINAIFLASTYTTISTRYNTKLAMFYNNPDAVYASVQPIMLYSFLQGLSLVVMHFVMRYRYGVSAMYHLAFAIERHGRSIQGKMIAYAPLIFYFTVIHYGMDFSLKFDWTVPDTVTVPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEN1</accession>
    <name>A0A8K1CEN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEN1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="46322" checksum="3206FE9E283D7360" modified="2022-08-03" version="1">MNVPMAANAQTAKYDFCHRRVHKLESASNCPEGYAKSRIGSFCSMNCPSHYPIKCGPTCAAGGSSCKSLALRQAKKVTDMALFLATGGALGAIKKVLENFNKVKCPAKIASASIRAHFYATQNKPQRAVDKLQEAVAACIGASAITQPIVDYIKKTVEQYKATTKNPSDAFLELTAIGEVKKAIEKQQITPAELQKMNNVMANKQACGPAIQSVIDDVIDFIKDKRPQIRDINAMHEELIKSDHLLDKVPAVDKLCFPGNTPEREKLMKTIDTIIGGILAEAYIEADANTAKSQIALEVAKFGLDTIAIFDPSGIAALINSVVSEFCTSSSHAQAVDGELPVETDGNGFKVKKSMWTNEVANGKVNIRFTNSAKRAVGLKFYPVGPRCRLPRSPTPTHYRSRQWAGATESRSSQESRNSYRSFSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFD3</accession>
    <name>A0A8K1CFD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFD3"/>
    <dbReference type="OrthoDB" id="164578at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="834" mass="90078" checksum="05F4289FCDDEF8D7" modified="2022-08-03" version="1">MQAPFHKFESPDSVTYLGQDGSTGSSVSTSIKGKPLSELGEEPSSLPTSLTVAVSIRRGRLLLLTLVVLAVIVGVVLTLAHGVELLRFNARSKDTLAREKLLDQYNSYSGTVATALGKPVEIFVAVLAQLIILRLMAEAYTRPVISKWQILTPIALSVAVGFMLNNGFGAANVQLREDSMRVVILASDLSVPSGPNAAVAARMTTVSQTVSETTPRNLITNTVLRNAVLPRVTFKQTLCDWEETQYESLGDDNSPLPTVDYGFTQRDWQSRILQEALPAETLKLVVNATKKTANDGLKSADLPMNASLAADLFLYMMIVAPTVFPWGSFYAFQDNESASSSISKKSSVVAGLLPPSETASETEQREWFLRAANASVTRQFAGAVNTSRRDIGVEFSHVEISPSIHFDAVTLEVEIDPRLLASKKARNNATRQTLVYQAGPPGAPSNCGPWPALCLVEKPMYLPKPSSFIIDALQQVHAFSTCASQLGDTLMASDAESFVCNESSNSSIMVMSVGKRLAADSLVQNETYGTAGEDYPTALITNLRKVYTFTIGRLSWRLENLATVYGAECGTSASTPNCSGLHLPLSTSTLSAVGLVRDGPAVEQHLVVSAEALPTDLIMPSTLLGKYKPRAVPLVEVSEWPSQTRSGGDILLPHNIDKLVWANTTVTDQNCDAKMEGLLYTKLNNHMYIEHGFQTAYTAATFFLLQNAVVKDVVSVPQGAQATTLDFDGNIQEMVALVSTPSQNAVLTLVGCGVLLLCVLWAVIKTSTNQTDPLGGITAPQAIARVMLDDLQFPALLLHRRVTHHDGEACEPRKLDEFTIAQLTIVHEADVTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGK8</accession>
    <name>A0A8K1CGK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002082</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGK8"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="58"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="8">
        <location>
            <begin position="321"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="47242" checksum="6B946FA7C43AA3E8" modified="2022-08-03" version="1">MPLCAACQETKGFNKFHADQKRARQPVCKQCFRTGRTPVVIETDAEEIRKKPMTLDSFQLLSVIGQGAFGRVLLVRHKTTAQVHAMKIISKKFLVERESVLYMKAERDIMTKIRHPFVIHLEYAFQTDAKVYIVMEYQSGGELFSYLRREGTFSEVKARFYLAEMILALEHLHAKGIIHRDLKPENVLISAQGHVKLTDFGLAKEYREGDELLTVCGTKEYMAPEMLLGKGYDSAVDWWSLGALAHEMLTGHPPFRAKNAKDLQQQILTAKLQLPKWLSPEAHSLLKSLLERNVSKRLGGGKSTMFVVRGVQALKNHPFFKKIDWPAMEKLQVPPPLIPRVMGDTDTSNIDVKFTRMTPGDLLCDAVEAEIDDQFRGFSFYGFDSLVTASMATMSLHRRPSTEVKSPINSLVTTLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGZ0</accession>
    <name>A0A8K1CGZ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGZ0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="557" mass="62104" checksum="9527F47CCF10EB9F" modified="2022-08-03" version="1">MLATVTYPSSPVATSAYTQARTSADTNTFTDTSTALFDGSLRRSAELPVSSTAFEMRKMLSWRPIHLELVASNYHRDRANTTSADDDDDDVDVDAAMSTAMNIAKDQQVQLYCRSTTRRWARAKVFSLRGPNAGAIRIRTKLEKMEISITFTTRLHKLRLRTNSSKEYEQWFYLFIRSASNLVMEIAPHKQMVQAEVEVKVEVKVEVVDADIKNQDVPVSDARVLQVIRDTQACEHVAIVNDDDNDVEANVHIHSDADTDTAQVDARLSMCWSLAGSFEADLHDAHIATLQIQHAEIGTDAEDDEQQVSQSCPTSPSSTPTSSRSLPPSLLFFSDKDDVEGDECAAEDADDVEDDECAAEDADDVEDKHDIDDAEVADDVEDYRGHGDRYVPSSDAWKAYLIVSDEEYQVTRGVQHRESSLWSLDHLAPLSRETSSAFLGATIATIADEDEDEDEDRRGRQSSQGRPPARDPPDESPGPSIQRGDTMLDVSGSIATSPFRRLQLRLRYQDAVSHRRTPAGHQDRQLRLQDATNHQHTPVGYLDQHGRQDRHDSANSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH45</accession>
    <name>A0A8K1CH45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH45"/>
    <dbReference type="OrthoDB" id="73653at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016286">
        <property type="term" value="F:small conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015449">
        <property type="entry name" value="K_chnl_Ca-activ_SK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10153">
        <property type="entry name" value="SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03530">
        <property type="entry name" value="SK_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="2">
        <location>
            <begin position="296"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="477" mass="54067" checksum="BAB31FBDACF7AB15" modified="2022-08-03" version="1">MERRRSTRLDEEHEDVKKQVVAEAETQHSPLARRHSAYLPPDADDTRVHRAVSAMETIYRIQERYERRRAVDNAAFAVAMLGVALVFVDNEYAKSATATFVLRCANTILTVVLLALVVWRFLLERDILIQRNVLPPHVSVFRMPLRLLSLILELVICAICVPPGISGRLTVWEWKYHIAIDELESKLNTCVVPLKAFEGSCYLVYSYPYDILGLLALLRLYMIPRVILNLSDFSSYRASYLGAIHNVNTFSSVFAVKCFLRSHPFRVLAVGFTATLLLTSYALSIVEAPVNPTLAPLFNAMWLVVLTMGTIGYGDLTAVTLLGQTILMVGGMFTGILLFGVLSAAVFGFLALDERDQSFLHLLRRQDYDQWLKDASVQSIQAAWRYFHARTLLRGSKRVQSRLQQQLYHRLAKQRRLRSQSVEDYRSTVTELQHCQDQLLVSLRADHTVTMQNLRDMEQRLDGLILAATGALSSPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH46</accession>
    <name>A0A8K1CH46_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sof1-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005562</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH46"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000132">
        <property type="entry name" value="DDB1- and CUL4-associated factor 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="9">
        <location>
            <begin position="355"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="404"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="446" mass="51026" checksum="4B2E493C4A984023" modified="2022-08-03" version="1">MKVKTISRVEKDFTQEVESDKLKVFRNYDPSLHPFERPREYTRALNAVKLDRLFAKPFVGALDGHSDSVSSIATSNRSLVAFLSGAADGEIRVWDLPRRKCVWNSYGHKGSVRGLTVAPNGGIFYSCSEDKTVKQWSLEVNDDDEEIPQALSTFTSKEPFLGIDHHWSKDLFVTCSSKVQVWDPHRSDPTHEFSWGADSITAVKFNPAEESLLASCGSDRNITLYDIRMASSMRKVVLDMRSNALAWNPMEPFNFTVANEDHNLYTFDMRKLNRALMVHKDHVSAVMDVAYSPTGREFVSGSYDRTIRIFSINSAKSREVYHAKRMQRIFSVKFSADSNFVLSGSDDTNIRIWKAESNKKLGKVTPRERRKLEYNESLKERYQHLREISRISKHRHVPKAIKKAADAKREVNEREKKKTANRRAHAKPGAVPFANVREHAIVKELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHL5</accession>
    <name>A0A8K1CHL5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_005488</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHL5"/>
    <dbReference type="OrthoDB" id="10250817at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.140:FF:000001">
        <property type="entry name" value="Signal recognition particle GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP54 helical bundle" evidence="16">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="100"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="15">
        <location>
            <begin position="101"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW62870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="514" mass="56401" checksum="0F4A893E495768D9" modified="2022-08-03" version="1">MVLAELGSKLQTALSKLNRTTVVDDEVFNQILKEICGALLESDVQVKLVRELRDNVKLAVNLEDSGALANRRRLIQKAVVDQLIHMLEPEAKPYKMKKGTSNVVMFVGLQGSGKTTSIAKFAHYYQRKGWKTCMVCADTFRAGAFDQLKQNATKLRIPFYGSYTEADPVRIAEEGVAQFRKEGYELILVDTSGRHKQEADLFAEMKEVEAAVQPDDVVFVMDSSIGQAVYDQASAFRSAVDVGSVIITKLDGHAKGGGALSAVAATGSPIIFYGTGEHFADFEGFNAQSFVSRLMGMGDIRGLMEEVKTSGMLDNQEEMIQKFQKGVFTLRDMYKQFEGVMKMGPLSKVMSMIPGLPQGMTQMLSMGGGEEEASKRLRKFLFMMDSMTDAELDGQVQISPSRQTRIARGSGCQLVEVDFLLKCHKQFATVVGRMGKSGLMKGGDAALGKQMARNPNAVMQQLSKAMDPKMMAQMGGAQNIMRMMNQMQNDPNALAEMSKMAANFGGLGGMKFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHM2</accession>
    <name>A0A8K1CHM2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHM2"/>
    <dbReference type="OrthoDB" id="167133at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="559" mass="60081" checksum="0B78789056892183" modified="2022-08-03" version="1">MSESPVKDDGSAAMVDVGSSPSIKHETRGTDQERPSPSSERYEPSEWAHIFDETNMEGLEVEDEAMDEADTSNAPSFPAGGSPGASTSEVDAAYHPLLHETTPTASLLEPWNFFETTMSLSMGDFASSFSSTMTNPLVGMSPASGATVSPSISTASPVSRLLPPLHQLPPLADESASATIFGSAFGESYAAKNEFRQAMTGASYPTHFVPFERQSDNTPFPLSKPIMREDGVLLVGTEMPTPLAPSSAKNRIFVTNFRSFHPSKPAPFIQVQAEVRYLGWLTPYSAVAAIGRDIHTLQVGDASGDRCCRLQNAVKRVHSDTIREIAVNSVSPTTIASGGFDETVVVLDLGRAGGDSSAATLTTKFDGCDVVSSVRWIPQQATCMSWTTDGGDFQVADLRVRTAQLQIPLYSFLRLDQMGGLFCHEYMSSNNVALGFEHGEMLYVDLRMPRKSSCYGSMRSPLSVLGEMRRSRDGGFGLFGMGGFSTASVHESRRLDSMALVGFNQNDPSSGVYKTYGDFSYETGRMLAVSDNHGVVSVYNGNISSGGATTAGPWREQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIG4</accession>
    <name>A0A8K1CIG4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium-dependent phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC34A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIG4"/>
    <dbReference type="OrthoDB" id="67833at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037997">
        <property type="entry name" value="Na_Pi_symport"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="57381" checksum="C25E5B6E8F87E2C1" modified="2022-08-03" version="1">MRKSQRRSTANESRVYTITEFVSTPASDPSFEQSKYALADYQDEVVEDEFQGQTSWRDVFSVILHVIFALCALYFFLVGIKLIGDGLTLALGCNTKDAFDFTDYPIQGLVIGTVATALIHSSSTVTSITVALVGTGAMTIRQAVPVVMGANIGTCITCILVAFAHVGDIERFERAMAAATVHDMYNIWSVIVMFPIEILFHPLEKLSIAMSDAKVSSGSFESPIDAIVDPFSELLLVVDKNGISDVATGKATCEAGHSFLIGGGFNKTSLRDGAAGGIVAAIGFVFLICALFTLVKMMAKVFLGTTRRVIARALEYNGYLNILIGTALTFAVHSSTLVTSTLTPLAGLGVITLEQVYPLAIGANLGTTATALLASLVAAKSNAVAIALVHLWFNIFGIFLFYPIPITRRPILSWARNTAAWSAAWPFSALIFVAMCFLIVPGVLLGLAYLLTASSTAATIVGWVFLTLILSVLVVFFFWYVRKGGRERWHGFLERKRLERQRHEEQEDAQDELVEPEREDQYHGQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIP4</accession>
    <name>A0A8K1CIP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_012933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIP4"/>
    <dbReference type="OrthoDB" id="1905920at2759"/>
    <dbReference type="UniPathway" id="UPA00896">
        <property type="reaction ID" value="UER00863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000038">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA lyase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000138">
        <property type="entry name" value="HMG_CoA_lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01062">
        <property type="entry name" value="HMG_COA_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="35"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="35480" checksum="C60D6F63A9955B1E" modified="2022-08-03" version="1">MALWTLCGVGAAMRKSVSRTRSFVTVGGLQYPSQVKIVEVGPRDGLQNEKSVVSTEDKVQLINMLSQTGLKAIEATSFVSPKWVPQMGDNTDVLTRIDRKPGVWYPVLTPNLKGFESAVAAGAHEVAIFGAASEAFSKKNINCSIDESLERFRPVCDQAKELGIRVRGYVSCVLGCPYEGHVAPEVVADVAQKMFDMGCYEISLGDTIGIGNPKSTLEMLRATKAVVPVENLAVHFHDTYGQALSNILIALQEGVSVVDSSVAGLGGCPYAKGASGNVATEDVVYMLHGLGIETGVDLHKVVEVGDFISNVLGRQTNSKVARAIGPKVLASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ44</accession>
    <name>A0A8K1CJ44_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72727at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2419"/>
            <end position="2439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2469"/>
            <end position="2490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2532"/>
            <end position="2553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2632"/>
            <end position="2651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2671"/>
            <end position="2690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1698"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2022"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2975"/>
            <end position="3048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3918"/>
            <end position="4004"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1351"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1480"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1943"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1698"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2984"/>
            <end position="3000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3919"/>
            <end position="3939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3942"/>
            <end position="4004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4004" mass="452433" checksum="D2347E52A104AE3F" modified="2022-08-03" version="1">MARKPELDLDPHLQIFDKDEERQTLQRRMSQLSPRREALQKQMSQLSPRRTTQDSSVAIMTLPFYEEISPSAALERMFRLFQTRRENREQNAEGNGEGASDEDAQQEEIGRDEFNRLRRCIGKPVVTEREWMRALEELGMADDKTHVRKRDFKALFGPPPFFGTPDVHDIIKNVMTADECIHFSQTLLSRFGAPADDDAPDDMVIGLEGIRSIQRGACLDTELSDADWKELLKKLLLPETQKHLDWMQFAESFHLPIKNKKIFGTLADPASVVYAVLANDKVLETIKDPSDNFVSRKAFTNLLRLKKTKMDDDKWMKLLETMQTRYQYRQPGEHIRSDDEDDSDDEQNDRLDNEQPLVVVRNTRNQVLSYEITFDEHGEVGLDLQSDFYGRCLTVAEIRGQAAKHKIIQKHDIVAAIDSVSLTYDRIALSKGEEQDRVNQGMSLLQGDRVRKITFHRQESYFQYEESAQTLHLFMKTLEEVPHDGKFLVQMPQGSSWGPISYEPGLETDCLRVQFDVPKHEELDLATVAWNPGSESIEITLQGEIAIEGNSTVVIQIAGLACGEQRLVGPCELSDGALTDAEGVSIPTHYVSLHTEWKQREATLQHNPVRERQYRTGKHFDESLKPLVHVFDPGESGLTLASDFFGQCVVVDKIKGFSQGAGFKVQQNDILTTIAVVGENESLDFVNCIKPFASNKSGANSHLSEVRKRLTQCHKSGQKYRLQFLRLNSYFFHDNGRTIFTLHARTTLRGGTTLFVKMPDTKWIVDGAVTASIADPVGTKVRETFWDSQKHTLQVVLDECTIAESTPVIVEIHGIVPGVRTRCAGPGEVTGLYAGVSTNPPEMEFELHEHWHSFLVGHQGLESSKVAETLKKFSTSPAMLWEELEYTSQLFDMYKPSDEEHLSLKDLNRLISIVSGEKEQMSTVDWNALCRNLGAKPLVGLTRRQFACSWYDVVGLSKTNAKDIYVRLHTAERIFKELASIYQEGDDQDILYEDTVERLAKFAGLSENVKQKALKDLKDQGSPGWDCDTFFQIVCGRHPIVKFDDNAMALWTRLYYSKLLFSTYSTKKIMGRKNLANLLAATRIAEPKLTNEKWTEICDSVNVDDSTGLQLADFLDVYADDLLGSRHAVADWHRIETFKLLPERRQKDNESKEATLSVAPERVDVKDIAAKALESTASTDELFQALLEKGLEFSKLEKIGERVATDFTFKTNLVAKRKSRARGFLNIQVKNITSLADHLLQQNALFNDRKATEELYIMFELTDARGLRYRLPDRKPKSRVARLKEALFGESDTAPEYIIKKDEIWDEDATQKLMRAMSDVEKQLAKTLPPNEHQKAIITLKQLQSQLTPRKAKIRHALEALEEQLENMDSKSPEYMSAVEKQKQLKELLSPKVPAKNAKKGEPASDILPMVEEFGNFDGHIFSSLVLRDQSPDAIVKFPDDHFRLFMDVPEDETAASQLYVVCKLFKRVGSMRSNCEVKLKAAQNRLNKTKGTLKVLQELVDQQEEHLRHVIADEHAKKNETMNNSHIWTVVSKLKQKRKDVMEFEATDVKKVQEEVNEMAKKLDEATKKELEALKLLQEEAMGVIPDAEPVTPGVVSPIFNKSELKQAEKKKRHLLEEFRKEREAQRIKFIGQASFEVDDLLAALHDDQKHTEDLAVFRTEENVDVGAVLLQFEYKCASLQEQEPARRLPSYLVSIPEDEGEDEDKDKDDDEKPQDNESKDEKKDAPEVSLVSQNAVEEEAFEFPSHSYLEVAWESGVLKEGDRLFLIREGSKYKLGMPYFFMLWSAFDEAGNPTAGGQGGVGDRESSDHSLCDWWIPDNLKESYLSGPDKFVRTEHSKREGVVLFPSSVELSLPPGVYRVYLIRNEVDKGGGKFRTVLGSTKALTVMPGVNGVHTSFGTTPLIDIKPLSASLEVFAASEQRGAKIETPEEQSSNDEMKLKWAEVEQEVEVVKRDLRMAERAYQRIKERKENKDGKEFERKKTSTATQAAEKKISLLKAALEKAETEKEKLKVMKKEALANAKPVSQKEAAQEKKAADSASAARQSAGLPSVEPVVFSYHFQGGNPTADDRILVLPADVVRVSDVLRSTILGKLQANDSQQVAKARATLERELKEVADFYNMRITFKQVKKVIVQFIKPASATTSDDSFVWAECIKAYKTATPIARKCFAYIIRDLLDEIAARKDQLGLEMPTDDDASSKNPSKARLSRLKKLLKIGKEIKVPLTAFTRGNSHTGASKNATNQEVWGHVVDTLGHSFRQGGFFVAKYVRRPAMISNPQVNAAAGELCRYGPFYVEPARISFNPRQVAFMLAKHAYKAATSDEGMAAMRVAGQFILAFLKYFLSVVSLSFNISVLAGNFHVDVSRLQALLNTFQQRLASYYGPFEYALTRLYDFFDGYIQLLLGKLDFFTVAGECMTGFVLWGVLAALFAATFIVYIVVQEDILLKLHKIHAILPFNPGKMVLAFFEHVGALLVIPTYLAIKSCVLFISANWSDMYHTLNDDPSSTLDKLKLRTTATTTCPNVHLAKINHGFGIAALVLITAFLFVCFPLLLLDVFSWVPLSELEDPNKLKELARSYKRLDIKAAVHSNANLITMPGLPTRAKKVLKGSSKRLAVVRHKLWRVYFTITPKPIRTFFSWIGWLLSCFIPRYAGFQTHYHDYTTKDFRTLFKLYGIIGLFCIFINIYAHLMLQSIKRSLGVLLGWRFRGEYMYKKKEMKPQRAWAFIDSFCLRFNFAWKLQYIKDKMVMPVVNVFMVTLGLWGESQWKEFNVEERANECFRMEPSGEIKQLQMMTLHGKIISLFWLCIPETMVLAYLAEVLNRGPVFSYFLNDQFLQADIPESEREKDPVWRFHSVMAFKGEDDVVYLSDTRFYSTLMKWGSSVVEIIFLLMVYGKQTQNNAVYFGITLISSAVTPILDLNQHLIKAYMEYVEVAENLAASTGLLEKLEKTKNVYDAAKEKVDAAKDFQENLPGVKVRMVPTGGSQPATLPNQQQPAPAPNQKVGALPDSPPPPVTNGNIQRAAAAVPPTPGQSTDAPGPTASVPPPPPPPVVGAPIPSVSMASKIEGMAASAIGAQGISLEIGSDDFDLEDALSEGVDAVQDGVDGAAAAALVAVGMSKLKKELILLNAMPEVSYVVLTDALEDGEGEITVSWHINARQRFHALDAIGMFPARTAGDTSVREMKDCICYRLLKDNEATPFGWKPRHENEDAERELVLRQAKSLRDIAVKEITDMTNASTKPHENSGYEDHEQRVERHQELLKQAGTTMNTMMHSPKLKPYKKKLPDILEEEVIQKKIASPRTSRVYSIAAAALEDAGKKARKIIDGQAKFRPVKNCVPEDDPEYEGFVYGNDAGIYLSKYGLHAYEFCYLRYNDLEKQVGISNEKDRANASKVTPVKTAPEKYEILERFVSNPVQIGTFNLFMNLTCDQPLVGARQKLNLSWTIYGVGYSTLSDPLCRNCVGFYKVDNTNTAACSRVEIIPTSAYLQAADSDPCAGRMMVTSPSEPGIYEIRFLFNFFKEAQLHRQCQVFGILEDEMQQLRIRSFYEHRALTEELRKFALREPKMWGVARMNTFAWLKAMLLSTIREPAPAATMESTTEFAKFLYVRLKKKLQQGLENPSSVYQRRISQMVAPLRLGSFIQVLAVALQSNSQVNDMMASVSFISPTEEDEQKRGRNPARDSLLLASDNELLRYGNISFCPLAASYLNRPSLCGYHDFVDDILLNHGQLILTVEQVMNNVSTSCVALYESAIVDAIAEMKVVAKELNLGTAMQGIYVILTDICRSHIQSIVRALLETDCRTGRRWPGRSEHMHDRIIALRAGTLPPEDEIFEIPAIYPQLPGGDAPLTRQYVALRRWIRPKLQRKIVNILKQRYARLLDGNMLILMEMSRACYRPRPSLVGVPFPDYRRMKTDSSLYFLAESRDEDGKPKPKEVTQDRSADNIEAMDDDDKEKEEEEEKEEEDEKQEEEKQEEEKEEEDKEDEGQDNEEGEGEGEEEEEEDDGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ80</accession>
    <name>A0A8K1CJ80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ80"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTPase_Era-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="GTPASE ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698:SF2">
        <property type="entry name" value="GTPASE ERA-LIKE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin N-terminal" evidence="2">
        <location>
            <begin position="55"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="460" mass="51758" checksum="34888B5BBB25F161" modified="2022-08-03" version="1">MAAKDARHNALKGDSNALGIMNQVHALYTNADEGLSTLARRLGLTIHPPRRKVNVLIIGNHSAGKSSFVNWYIGDQVQRTGVAIETQGFTIVTSGSKKTLAPIKGESSVMLYPYLEPLKERFGKPLIENLNTCVSTSTKREFPMVDFIDSPGLVDGDISYPFDVNEAIVHLADSVDLIFVFMDPMGQALCSRTMNVVKMLNQKHFDKMKYYLTKADTVHNPKELMKLMVQITQNIKQHINNQHGLEIPAIWLPESSGGKRPGEPVLNDEVNQISEVCATIEKAIHQKVQDNLSQVEKDCHAVVEKTNELLAKDEMEIAAKKSRQLVAVFFAVCAWTIPLVTFLTLVGEYKHYLPEAILEAEYVSSFIDTLYDGIRPLLLAPEEKLGPVALVKFFGISVVLFLVLNGISKFTHARASKFVLQKREVISKWRRHEQIAREVLHRRQELFLEYVRAYTAVEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJC8</accession>
    <name>A0A8K1CJC8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJC8"/>
    <dbReference type="OrthoDB" id="69789at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="207" mass="22227" checksum="43A8017E2267BA2D" modified="2022-08-03" version="1">MSVGGDDKKQQPWDAALESVKESVDGAVKGVQDALGGNVQQVKDLARGQIDQAQELTSSARIAISRLGKEATQGLKNVVRPVIQIFEQAEGKEGTQLRKQISSARVQVNHQLYDAQLKLQETQKVADEQLVPVKSALAVAQTQLIKVNNFRKLHPEFALAGLVAVVGVPSLLFRGKLAATRNVLVAVGAGAAAAYTSDKLAERKERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKH4</accession>
    <name>A0A8K1CKH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009366</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKH4"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF33">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="46"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="480"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="546"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="656"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="129"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="750" mass="82782" checksum="F1682C32BF9140CA" modified="2022-08-03" version="1">MTSDHDAQDEKPSSENTSVVATTQLFVSATAPPSTVAKSAVALPSRIRVVVRVRPRLSIEQSHSCTILCADSERNLVHCGASTSTNKSFQFDQVFDGQTTQNGFYDQLKMDRMLDAVLDGYHTTVFAYGQTGSGKTFTMEGYDYERPRDMNIGSSGAPQARFDTSDRIGLIPRVIFKLFEHIARSSSREFVVKCSFLQIYNEQILDLLNPAHFLQPRSRVASKLPVKNGNSRPSSQQGLRLRWSAVRDFYVENLRVMECSSPQQVLQHFQDGIKHKIMASHNLNAASSRSHCIFTLYVESVDAVSSPNEILQSKLALVDLAGSERVDKTGATGVTLRESIGINKSLFVLRQVIQALSEEGSARGGLTDVLGQEPPRNKERAYIPYRDSKLTSLLKYSLGGNSWTMMIACLSPSDAYVDENMSTLLYASKAQSIANTPVKNEDPKTVLIHELRQEVESLRRQLAQAQNIILQFRQVSPSAIGSSESANEPPSTTSSNSTEPVSVEKPLPSVPETVEIKSSQIPATNTKLKMKVIDNVELIKQLYTTEKQLTDRVRQQEVKIADVQHETRVLQVENQSLREKMEVLEYLLATQKPENSSNDQDEADIMDIPEYGSLSTSASDPLVLTEPSTIKMRAVTSRVSTKGANQTPPTRPAPRQSPSSNQEKPPTSRHSNKAKKTTARQDGDTGLLSLTELRDLLGGKKVATPSTAAKQSENAPPTRNTMPRTPAAPIEVEQHPAVAILTTLEREKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKV3</accession>
    <name>A0A8K1CKV3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKV3"/>
    <dbReference type="OrthoDB" id="59491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="269"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="686" mass="77363" checksum="FE075F96CDF93F8B" modified="2022-08-03" version="1">MTSFRGRIFHPDVGYPLRTLLELHLRAGVGSILSKPLWWVKWQSNDGEIRERWLQELEDLVVHQTLIWTASNWSVYELRQAILKLFLEFPRTGSEDEKRAFLESKLPLMDFYLLAKVKNSSEGEATQDNGDVSAAVKAKSDSMESLGQLLWYFGLLAFKRDLKARVPQDFEPGADFKIGSDAGIELTQSLIRQMREGNRTQESFLTWCEDADTRPHIVEGVWLHADRVMQELDTIRQCVTATLNQVISEHDLTSANVSGFISPGPVPETWMSDTIIPADVKLKFANEVQVLEDMPHTDKDWHPGSNNQVLDLVHPSLYCCVFGKTMRAPDSMCPAATSSKNALEHMERIMFSGTTLVENEYRGDAKYQWIPSGFAVDEDGHVQILSYINNLHPAKYGDMYLSIGSIFEKFVPMFDKVLSSLVNEDAPSPSLAIPDIYNRDTDEVPPRPTVPDVLPLQPTCLTEYTIKGTTVQVIVKVAEIHLTPEKPAYLGGAWHVEGSDAEQIVATGIYYFGCENITESKLSFRVIVEAPDYEQDDYLGMAATYGLENEELLVQYLGSAIAREDRCVVFPNTLQHKVEPFELADKSKPGVRKILAFFIVDPTKMIPSTSAIPPQRSDWIQAAYQPIFAGLQQLPEVVLQDNMKQLLDNGMSLSEAKEHRRGLMDERTPVDGAEDDYELFFSLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL61</accession>
    <name>A0A8K1CL61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Niemann-Pick C1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL61"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF9">
        <property type="entry name" value="SSD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035469010" description="Niemann-Pick C1 N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Niemann-Pick C1 N-terminal" evidence="3">
        <location>
            <begin position="72"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="356" mass="38106" checksum="6470D4A9E1F9D671" modified="2022-08-03" version="1">MTMTTTMRWTLLATLALLAGVYEVQAACVMTGTCVNPGNVPDYDACIPEANPMPVDPKPMTGAGWANVTGGGACTTDKECNKGACVRGNCVCQVDGMTAGAHCDDFAIQCPEYKDAACCSWQQNQALAQNFKLVTTIFGKNSVGGCDACATNLLELWCGMICSPRQSEFMKMHLPYPSNSYRPDPMTGKDHVKVLEMDVTLAKDFTCAVFDSCKNTAIASVSEAMKSSLGFLNYQMQTGAIGHGEYMHLHFNATSNATAFDHPVLNCGNYSEVEAIKSKIPTQAQLLPSIASPTEAKQCPCGACRATCDAHSSSSSSDRIKVVEHPISIWDGFNTKLVAIIYGVAAVLLIGLQWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD3</accession>
    <name>A0A8K1CLD3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD3"/>
    <dbReference type="OrthoDB" id="105621at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="106" mass="11426" checksum="DEE87637F4ED0083" modified="2022-08-03" version="1">MVTRDGTARAGAYALARDVKERKIYVITDPESLSIDEIVSQVCEAIEKPLEVAQVSEDELAKGIAVGLGLPELVGQIYASIDKNTAAGLNFSAECRYLNILCSPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLD4</accession>
    <name>A0A8K1CLD4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM98 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLD4"/>
    <dbReference type="OrthoDB" id="203430at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018797">
        <property type="entry name" value="FAM98"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31353">
        <property type="entry name" value="FAM98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31353:SF10">
        <property type="entry name" value="PROTEIN FAM98C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10239">
        <property type="entry name" value="DUF2465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="190" mass="21755" checksum="0FC51C1B982607FC" modified="2022-08-03" version="1">MSDEELLQRIQELTTKTQEQQHSVPVKSVEAPTQLNATERAKLVSINESFRRDYTLRRALMLERCDVTLESFTWSKAGKEHQTTMEQELQALRSTLAIEPRVLDLDNVFPEKQDAREVIKDPVSSLRTLVIGPVPDRGGRTDELDDKTMNQAAKGTWGSQTKRESKQFDKQRKSKTRKTKQKLAIKGTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLM5</accession>
    <name>A0A8K1CLM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLM5"/>
    <dbReference type="OrthoDB" id="6123at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="9">
        <location>
            <begin position="165"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="433"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="621"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="869"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="651"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="753"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="801"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="874"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="896"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1025"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1048"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1069"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1080"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1181" mass="130432" checksum="893AC379A49FCDAD" modified="2022-08-03" version="1">MGDAVRRVQRHLQELSRDHLVSVEERHDANLAWLQIELQQLCKQIDVEVRVELLRPPRLSLSKRASLVIPDAPVTHVETLVDVQEQQAQEEDDAPAQMEEEPIVEAPEVEESVEVANSPVKIQQTTKHSTTRVVKKIVKRTRKVMRPKQVVRATKKKKSRFSIDVNVLKVAELKNELKKRGLKVTGNKPALAVRLREALDEEDAVMYAEKLGDEDDAEVEMEEVEEEYEEEIEEAVDADASNETQDTQDAMMDEPSDTQETFDDSEVPTQKTIVTRNKSSQDSDSRRSAATKSSRSEIDLTSPEDEKKKKHRGPKKSLSDLVSVEQADEIVRESAGSEFLSPVGSAKPAASKAQTTLDEPTKVHEEKATSKIVKEVSPVTSEIAVKEPGRTRAVGDLKKATPPEMPTTTRATTPDVEITVESRINSLTKTLTAAVSGKTSPVIPTDDLTTPQQQKATEERNIASAGALSSRTDRSTFSASSALSTLSRRYNGSTSFVDDSQPEQSPHRVSFAPDTIDTSSQATRAASTSGLEIQLSTSTAKTPDPVSSSASSSQREAHSEPRVSALKQVENELERKRREHQESIQKEAQRLRLAAKQSAKKRFEEARASSLFWAKREQLKLQLQSGSSAEKSSPRTPDDTVATSTWSVDETEPKQAEPEESKVEATVKTVSPREEQPKASAQSNQSSTMTRRRSSEAKPRTDEDHVGSSKQASSADIKRERSLKRRSSASDYETRNPPRKRVSLAKDKDPSSKRTSLTKETISSMNKRTSTGKERIALTKRGSLSSQSNPVAKARVPTDASVSRIGGSTSGTGRSSNKRRDSVSSNVSSSSSSSSTSEGRSKLQSANGGARKPTNLVSGLHSFTSLIDKDAGISSSQGSTTSTSSRQAPVVNALKMAEKSRMLEQKKNMEKMKRKEALMKKYEEQRKQDEEKKKRLALAKEKAEREARLKREQEKAAEKKQREQELAKKRQQRLQEMRAGLEKKRAQIAAEKVANTAKSQASASREAASAKAQVQASAATVSKAPTSSSQQVKATTLLETLNPPQPSKPTKNAKPSKPSSASSANSKSEMTTYQMSENEQSSDSDSDDSKDDNNGKNIPKWAQRENLERALRVQFGPNAIDPTPSIFPDFVDSCDLEAIFEPTDVRKKKRFQRRTSSGNWLADRPTAREKAMYKREMGFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMB6</accession>
    <name>A0A8K1CMB6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMB6"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030863">
        <property type="term" value="C:cortical cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.60:FF:000005">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000003">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0117">Actin capping</keyword>
    <keyword evidence="3 4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="291" mass="32995" checksum="3CBBAAE0E2FC0B9B" modified="2022-08-03" version="1">MADAAWEYEDNATDQEKLQIAQHFLLSSPPGQVNDVLRDVVKLVPAHVLTDSALRGALHSYNVKSMLPVAVPDAEYKILICEDAQVDATHYVDPIGRRVLGFDHIKQAIIPGDVSDLPASFSTPFDSERDAVQKALQSYLQFEYMHQGTAGVFVKGSSLVINLCTERINLRNFYSGRWKSRWEIAIDSNPVRITGKMELHVHYFENGNLQLHCEKEVSEDTTTFDRANGLGDAILRVIKDTEDALQSNLEDMYINMSQETFKEMRRVMPVTQTKMDWSIHAHRTAKDLSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMK7</accession>
    <name>A0A8K1CMK7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_008053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMK7"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW65411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="19333" checksum="384C9AA5AD1B5EE2" modified="2022-08-03" version="1">MTPLPVEPDALPAYNDRQPSRQRRVASRVRQVVDSTGAGFVYGTIFGGIVATVEGYRQSPQHQRMRGIFHHVKAVLPETAGRIALVTCCFRLASLGMEVVRGHDADLWNVFFAAPIAGAMMKARHGPRAAMQSAVMFASVGSVMVIINELQGKVRHHHESANELLEEIAFAEEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMR9</accession>
    <name>A0A8K1CMR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMR9"/>
    <dbReference type="OrthoDB" id="102252at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="325" mass="35321" checksum="E1997082F98A18B3" modified="2022-08-03" version="1">MSTAISSSSKTSGSGSDTAGVAPPRRSVPIAPDTTANLTILEGTCAHYAQGPDGCALPRTCADCLLKKGCMIDRYGTCVSQEGFPFNSTMDFRIAQDRGLVYPNASDPSAVNIQSWEFPALSAGYCASSDPICRSCREARYWLPSFSADSRYCIGLSGCICIANCEINWNTYNSAVCITPNGSDNQNNNGSSSSSASGNGFFIWISAGILVVGMVCYWTFRQSSRFFRTEMIRRDVMMERHRRLAHEARLQSRISNMLGIQPLSLSGWMKHRQDLADKEKAELEGAVSPTTPTTTSTAFVSIEEASHDVVVVANESAARQHYYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN11</accession>
    <name>A0A8K1CN11_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Poli38472_003859</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="24">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN11"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="26">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="TMW66094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="473" mass="51685" checksum="31C21E0BA17A2040" modified="2022-08-03" version="1">MGLHSDLHAQDALAPRPARTLQKALVLFLCSALGFGSNYCFHNPAALKNQLQQHFNEAMGKNEYEVLFNLLYTLYSIPNIVLPFVGGFFVDRIGARQMLLLLTSFVLIGQLIMAFGSSILSFQTMLIGRIVFGFGGESLGVARTTFIATWFTKHELALALGISSSFSGLGGILNNVLSPYFSDQFGVSFALWFAAFTCGVSVIATLILIPVDRSAHAMAPHMLPNGQPRLEIAASAIKISDVKHFGLVFWLILTASVAMWGSVVPFQTVTGSLLLERDYFRRPPMECRRCGEGNYVSYADCSEIVPTCPSSPSYAWPLPKLSASCEIKRPIDQLYCSVSPPYILDSEINCDSLPWKNGPLTRTYCEKKIIAEEMATQVMSLSPLISLIGSPIFGYAVRNVRRRGIIALVASIIVVTSQMLVAASDISIGVILFAQGVGYYLFFAVIWPSIPYIVEEHHVGTAYGATIAVGSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN40</accession>
    <name>A0A8K1CN40_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004299</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="6">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN40"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0041">Annexin</keyword>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 6" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="37819" checksum="51FF7DBEA50B4D39" modified="2022-08-03" version="1">MLAIYPRSAFDVYNKIKINYPSNIDAICEEIYKACTGMGTDEEMLIKILGPRSPNDRALISYRYKELFNTPLRDLVKGETSGDLGFLMQLICMSLPQAEAYIIHRACKGAGTSEHLLYPILVGRSDAEMNVLKKTYFEMYEEDLAVMLNAELSGDFHQIIMLALQELQIEYKSSFHTKEKVEEDAEMLYKAGEGKWGTDEGTFVKTLFSCPPQHLENVNKAYTEKHGHDIINAIQSEFGGTATDALVYFVRLTLEPFKLLTERLEASMAGLGTDEMALSSFLVRYHPYLSKIKPIFEDKHKISLRERIHGDTEGRHRELLLHVVDAPSSEGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNM5</accession>
    <name>A0A8K1CNM5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_003978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNM5"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF61">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="528"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="715" mass="78659" checksum="18D4D598A254DE0D" modified="2022-08-03" version="1">MSTPSSTASSMPSLSPRSASRLSRVNTSSGSFTQRSLQAFRTVSLPGLLPGTSLGILASGLLDKRRDGAVRGGWAKRLFILSTRSLHYYRKAEEYELFGKERGQSPLADISLAKIVAPEDAPYGAVEPGMPSYFIAVISKRKSLLMFLRADTLELAMNWVNTINRAVQVAKTVNFSSRWPLEVIQKFTAVASGQFEEPAVEEVETPDSPAEVMQPTAPGILMISVASPPSHVSKASRERLIKRQVDLGEEVELGKLLQKDVCIIVLTDGEEVQVLQSLLGPDVKRLLSEEKEVVLSTPPRSKGVDSCVVSTRRVYATFRCEKAPPVPLKTQTSGVTPANQIPASVLSNAFPGGLGGLFLLSCVVAFWLAHPFEGLMKVTIFVGTVLALSQVAQVALSVATGKNETIGRSSSVKDFGVPAVAQSTVDDGPVFFLRIDKVEVVEQEQEPPKLVDSSSVEETTTGESDAAESDNGDIAYLKQISGGPLPFSHRFIAAEKGDEEKGRQRYENTLQWRKENDIDDILIRPHPTFETIKKYYPQFFHGRSKAGLPIYYEQPGKINLPALKKEGLSIEDLLRHYMYITEYLWRVIEPSDTGRSVTVLDVSGIGMSDLGGEVLDFIKRASAFTGAHYPERSAHIFIINIPGWFNMIWRMIKPLIDPVTREKIHMLKGSAILRELETLVDLDNIPSDFGGRGCRLGESQEENELREHVAKFLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPJ2</accession>
    <name>A0A8K1CPJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">B-block binding subunit of TFIIIC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_004032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68020at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042791">
        <property type="term" value="P:5S class rRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056467">
        <property type="entry name" value="eWH_GTF3C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24101">
        <property type="entry name" value="WHD_GTF3C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="B-block binding subunit of TFIIIC" evidence="7">
        <location>
            <begin position="186"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="GTF3C1 extended winged-helix" evidence="8">
        <location>
            <begin position="514"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="441"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="640"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1014"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="664"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1060"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1712" mass="195008" checksum="C961BE86EEA0679E" modified="2022-08-03" version="1">MMTKRPQELVAAAMDYVALEGRAGVAVSQVLDALDAVLDTGVRRHVWKSLQRQQARGVLQFYYEPTAVTKRESIGKKRKRPTSNGSRASGVKAVASDDEMDEHVTRKRDHQDREDENMTIEDTEDGDDARNRREIVHDVTQIPLEDIAPTLRSAKRLMVVACEELRFRAMNIPRKAVLAEFGDDHLRILEAIGRARTMGITIPELCGVFDSGSSVKKVHNSLDTLISYNLVIKRMMIVARPSMRRLNIVHLPRFAADFSPEMFDASAEFESDDLCKKILSAAAEAYLRDLPAHSCVLYDLGRDLGFQKRHLEVLKNHIVQESKRDERFPLEFFQAVLQPSKSASTEPKILNCVRYKPATDIKSRTPMRGMTIEMGLLNQIYRVIEDNGENGTTIIDLRNEMVLPGNKLPYKLVSILAGTYGLKAEAIILGKNKAFRLYPGKIKTPSKKRPATTQLDEDNDDNSDADPDTPNKPSRTLRPSSTTSRNGTTPENTFSVRANIALKVALGGTEVEGTRTRRRDHILSRLADEKIISISSLRASMFNMERQLAAGDDQNVGMIDTRSVTRIAIELEKESSLRLVQLPLPARNVSTKFRALRCVVLPGYEQNEQFIQGFVKNYCRDERLRRVHQNADQKRFVRFRPSDSHDDGFDPWRSTRAKKRPRADQSTSDPTQSASSTIDSAPDEVVSYRVRRFLSQEKSSLHNHQYRRLGFAYGVMYRCKEFHRFLWSFLHEHTELHLRDDDIDVSIDDEDEEGNDGDGTLKAKGDSESKKTRLRGIVFSRETVLHRMPVHLYIQVFSGGAVLNAHEYVEVENAVKQKQTFDVLPESVRQKIWAHESERTAKVLGTLNDLQLIVPHKIGMKNLIKILRAGYSDDQDGVLSQALKDNALGGLFRLRRSVKITLDDRVNSENGVLIGDSACKGMNDCSVIRIVGTTEKSYSFGSMLPLGFEFSTADEIDRYWETLQCLCLEKMVMEVPNPIRNASAVCEVPKPVKTRARRMYRILAWIAKSQKAPSKPTVSTDAQDTKRNGIVSRVIRASSTRRRKSVKKVASSSDGKDNHTASNGTHSSNGQTKLVSYPGIVDGDEPDAEAYLWSETDERQLVAYFIDDCRSRWKIPIPMGLQRDSETIAFRVPWLSRIGFGLVSIARKLGRRKIDVKKRLKVKLTEPDAKLMLEAAKREMVETLNPAGTFDEEVAIRSSPRLTALFRRAVMMIVSPQDEYHPLVAEELISFWNAEEIRLVWRYLWLKHWIVRATERERIRGYAMSQRLHDFLKFVTLSYPLELFRQAAEQEAMVHSTLEEIADTENTDRSKESDQIFEAEFPADATPGQCALELGCQVMGICTLLPEQNPLPEEEDDMVDLEDPLTKKPSALTRKRQLRFLNYKNNKEGTGFAAHLAKRISFKNPSVLTDSWHVETKVHAVTLEDPDEFRRFEAFSCVLDLSQESELRGTKRHKHVHKQLLQAIEKVVRARGECGISLDEMVRHLRDEESAISLTDVIDPKLVLSLINQLLDAGVFICVNDYSEQRYVVREHGDFWLLRPYSLIDDERNPQTKKVVFEGEKDMLSFPWLRMDGSTNHRFLFSLQRKLLSFVIMFPGITEENVYRRLEKLLTLQDTREAMALLVEEGLVYTRAISVPLPKATVTTNLFGSRKRRREALSDDTDAPQLVNLVGNVLNFDRSKYVVHYFPHLECIQRFGSIIQDYQSEAPELQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQH6</accession>
    <name>A0A8K1CQH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tubulin-tyrosine ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQH6"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070736">
        <property type="term" value="F:protein-glycine ligase activity, initiating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051437">
        <property type="entry name" value="TTLL_monoglycylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45870">
        <property type="entry name" value="TUBULIN MONOGLYCYLASE TTLL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45870:SF2">
        <property type="entry name" value="TUBULIN MONOGLYCYLASE TTLL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="55016" checksum="D2B10EF1A5AA3788" modified="2022-08-03" version="1">MANRPKVFVTDDKFPDVIAALAARGWRRYPHLSFPKFDLKWSNYSKIAWKRVASHQIVNHFQNVTLFSQKDELAARLYRLPGEKVDGFYPRTFDMAVEAMRDVLRAWFLYYRAIGVVKAAVGEHVNAVDEELVLLALSFLERIVENDAFYISLRRSCANMSALAVHDPIWMKMLRTPSATTGTTHCSPDTVDKCCQLLRELQERDPHVNTHVNTGMGDIWICKPSNLSQGRGIQVMTSLEDILALQDTDPNTNESTGKEDENQDNDDQRASIAGRKVSWVVQKYVERPLLLQDGRKFDVRQWVLITSLEPLQVYWYHECYLRFCSSPFTLDVDQLSDQFVHLSNYSVQKNAKSQRKAFSPMWTSSQFQQHLRDQHGRDVWNDDIIPQMQHATRVAIQAVLPELRQVGRGFEWLGIDFLVDSLHRVWLLEVNVTPDVSHSTEVTAALVPPATQDTLEIVLDGEASSENRWILMKGAEVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRC3</accession>
    <name>A0A8K1CRC3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012036</name>
        <name evidence="3" type="ORF">Poli38472_012039</name>
        <name evidence="4" type="ORF">Poli38472_012042</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRC3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036272187" evidence="1">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="112" mass="12834" checksum="4F216E5F66DB2A02" modified="2022-08-03" version="1">MVSASKIATVCCLAAASAVMVSTVSAYGYDDYDYGYGKNDYDYGYGKKHHKHHVRKHHKKDYGYGYDNYGYGYGGYGYDGYGYDNKKYGNNYYDDGYGYGYGYVGKKYNYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRH5</accession>
    <name>A0A8K1CRH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_012114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRH5"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42141" checksum="CEA52C9D57F34C2D" modified="2022-08-03" version="1">MAPSTTSKLFTPLQLGGKTNPIQLQHRVAMAPLTRRRTGDAGVHSQLGATYYKQRATQGGLIISEATNISPTARGYIGTPGIFNQDQIDGWKLVTKAVHEEGGVMFMQLWHTGRLSHPALQPNNVLPVSSSADMPLDEKRVVPTKDGPLPLVRPRALETEEIPQIVEAYRQAAVNAIAAGFDGVEVHAANGYLLEQFLFDGINQRTDKYGGSVENRARFLFEVLDAILTSVDSSKVGVRLSPYNKSCNQQDSNPAATYTYVFKKLNDYDLAYAHIIEPRGRHYRHELTPAEGATAFFRKIYKGVLISASGYDRESAMETVEAGTADIVAIGRYFISNPDLVKRLELNAPLTTFDDHSFYGVDGKPALGYTDYPFLAEVEVQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS98</accession>
    <name>A0A8K1CS98_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS98"/>
    <dbReference type="OrthoDB" id="544129at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF105">
        <property type="entry name" value="F-BOX_LRR-REPEAT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="3">
        <location>
            <begin position="161"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="2">
        <location>
            <begin position="369"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="684" mass="74575" checksum="E759181ADA10177B" modified="2022-08-03" version="1">MARPSSLRLPATSAFTMEELDFICATCVCDTESQLTDFRAQLEADASVDLDACCSCVYDRLTYMWRKKTFHHWRQVVRAATCSKASDVDEECRVMTRKDETEETLSVPPRIAQVLAPVLHIVAQYLHASDIFRMMRVNKSLAREVGLATRTLSFIPARRLVTDDDFVSLPSRFPNVSDLTFTGCANLTDVTVRAVAKLTYLRSVALKGCFHISDDGVKTLVKANHHLTTLNLGYCTELTDSSVAAIASHAPSLTNLSLRGCRRVGDAGIQQLAKLQHLRTLNLWYCNQGQLTDAGIAALAQMTSLTSLNLSNCSQLTDASIAALGSLVNLRHLEIANVGEVTDKGLLALAPLKNLITLDVAGCYNLTDQGMQVLTNFPLLSSCNLWYCSELSDGTFVHLAQLKKMRFLNAMKCGKLTDKALQSIGNLTSLTSLDLVSCYQITDQGLTALQKLQNLRSIYLGGCSSIQDDGIAGLAAIPKLTIVDLANCRQVGNRALEGLGKLQNLTNLNLMRCNHIDDEGVRHLASLTKLKTLNLANCRHITDASTDVLAGLKELETLVLWYCNKLSDEGIVRLSSLRKLQSVDLASCSKLTDAALNTFLNMPQLRSLDLGNCGLVTDTGLKTLSRITSLTALNLAECGEITDAGLAHLTSLVNLASINLWYCTKLTPVGIEQLSHLPALSVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSG4</accession>
    <name>A0A8K1CSG4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSG4"/>
    <dbReference type="OrthoDB" id="10601869at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="594" mass="65918" checksum="E51E069795AEC5A6" modified="2022-08-03" version="1">MTTTEDAWGLAATTVEALKGRVWLSESARDQGTAYPPLLPCYNWLTVQICDPKSRLYQQTSGQRDFAAYTRETWRAIKVWHALAKTPGFSPHENHAFWRRLLQEIVPTTLQDALEIHCDDRVFPRFRLVFYPRDCYDEDDDEETDAFDWIESFCETLLSAVEDDGDEVQIATSSEPMHSQLVLRTPMLRIHGPMGPTLQQHPHFLQRAAQLSAKLSSSIHGGSSWCRVTDCSVLPRGSMRPHEFVRVSMALDRSSVRLADVCIDLDDSDDVVEFVNAASKLSSVTFNVARADMAATEVIFALLRQSASSLRTLRLFNLFATGSTSDHQKLWSRLVSALVDSSVQELILERVQLNAGTFSAMDRELKPSTLACVTIKPLVSSSINTEAYINAVKCLGGSLRYLDLSTLCLSAQQVDQVLQPNPDLTSLRLGSISDVADSTLVRSLSSASSRLCSLSLSCDGPGVRAIASSLSHQSLDDVLASSHLKELAIRCHDSMETATSDALLTMLDTNHSLECVHLNMRELFHRADAVDPRFHLHHQRPLVRQLPSRHKLAFLSVLATDTVHPTLSRFDAGVASEILALAGHAVRRRVALRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT36</accession>
    <name>A0A8K1CT36_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007882</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000904">
        <property type="entry name" value="ABC transporter A family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000298">
        <property type="entry name" value="ATP-binding cassette sub-family A member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1070"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1288"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1325"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1349"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1380"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1416"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1449"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1495"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="700"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1558"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1017"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1026"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1960" mass="217375" checksum="BC8998EE85A431CD" modified="2022-08-03" version="1">MTEKRKITLGTHVRTLLWKSWLLKKRHPVATVLEIILPVLFIILLSGLKGLTTNVNVPAGWSDTSSSATDKTVGRSYTMTDYSGGFGAWNLGMDVGWIGSSERRYLVTETTMSGLLMYLSMRSADEMRNVDDFKTKADRISCTSQVGFFGAVNTDTTAANAIPANCRDHVTPYKIAIAPDNTFTRKYFLETMKVWYPQVAISKSNYNSASPVKIPAFEDSVVFFKNEAELEAYITSTEYGKTADTPKIYSAVVFDKYPMDDASIGQPSSIEYSLRFNATLGKRGASGDVPRTIGEPAFESPFQRTISTEPYSRYAMLGFMTLQTAVTRFVNCMPVWDASTKSTTGACQHQKAMATSDPALDVQLFQRIANDFFIKMALPFAFNDPTTAATELMSISSAEKEKLLVPLRIAPQPYFASSVAAFPVDGFLSSPFYESIKTVFALVFILAYLYAVSRILVVLIQEKETRSREYMKILGVQESSIILSWYITYIVIFFIGCILQAAASMGGLFGNSDFVIIFLFFFLFSLSVLAFGFLVSTLFSRARTGAFAGMVLFFFMYFVSSAFSTSSSKGSKGVACLLSPVALAFGVQTLATVESTGVGMNFGNARTVTDNFSFDMALGMMLFDAILYTLIGMYLERVIPKEYGTTEKWYFPVSPNYWRRKYSAKINDISTAEETVIDINPNVEPVGPDLRQQERSGEALIIKNIKKEFVVPGGIKKAVRGVSLAMYKDQITCLLGHNGAGKTTLISMLTGVIAPTEGDAYFRGMSFSRDMGHIRQSLGLCFQYDVLYAEMTVEEHLIFYARIKGYTKASMNEVVSTKIKEVGLTEKRKVFSAALSGGMKRKLSVAICLLGDSSLVFLDEPTSGMDPYSRRSTWEILLNNRQNRVMVLTTHFMDEADILGDRIAIMAEGQLRCCGSSLFLKNRYGAGYNFTLVKREKCDEKQLIDFITTRVPRAKVLSNVGAEIAFQLPLDCSSEFPQLFEALDDQLETLGVLSYGISVTTMEEVFIKVAEADDEDNQHTLKKDAGSPGATSTGPSGPSIANLTGMTMFFVHLYALLFKRFRVAKRDRRVLIFSAVLPVVLLAAGLALLKSSSLTKSDPKLPLVSEKFRYGTDMNVPYFCEADDSKWCSHVLDSLFIGGETEAFTTTDISTPPYVTPTPKVFNVSYPANEIDVPGTTGYCLRLSEKVYQRAFGKTDQETSKVTQTPVEGQYGAYLVHGDGSKQLFGYHTFVNTTALHGSVIFKALMDQALYRMMVSNADTSAASNLNLTVNSHPLPLTASTKALFGSFLSFTACIFIVIAFAFYPASIVVFLVKEKQREHNSKHQQLVSGVSLPAFWLANYIWDMMMYVIPFLAAIILIKVFNVSALTGNDCTVCTPETYPAVVLLFILFGFAIAPFTYVMSYFFREAASAQTYTIMANFVLGVVLMVVSFILDVVSESSKDANKVLKFFWRLSPLFSLGTGLLNQCLIEITAAFGRTSDKPSPFDMDVMGWEMLYLAFNAVFFFSVAVGIDFLLSFPKIQAAIFRDPVIQDAPYEEDEDVKKEAERVLSGRADSDTVLVKNLRKVYKGKKVAVRNLSFGLPKGECFGYLGINGAGKTTTMNMLTGNFLPTSGVGKLGGFDILSQQLEVRRLIGYCPQFDALFELLSVREHLELFAQIKGVSRRDLDKVVKELMHQMNLDDFEHKLAGTLSGGNKRKLSVAIAMIGSPPIIFLDEPSTGMDPVSRRFMWNVIANISTHRKESTIILTTHSMEECEALCTRVGIMVGGRLRCLGSVQHLKNRHGNGLMIEIKLDQAKTEEVEGRVSTCMGGSSSSVITPDQLRDACEKFGDASWFSKIDAKHATGYALAAVLERDGSIRPQLFGAWWMAEERYLGLNAFLQECFGNDKVQLVERQNDMCRYRLLGDQKSLKLSNVFRLVESGKQTHHIREYAVSQTTLEQIFNNFASQQNEEKGVARGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTC4</accession>
    <name>A0A8K1CTC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTC4"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF4">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="107"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="339"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="64500" checksum="C3946AD340549B82" modified="2022-08-03" version="1">MNPSGYAQGQGHGYGYGYGAGNASGHGPNAYTGGFHTQGDVPTNFSVNPTMMEALESAVALPGVFTDDEMHRTLRRNRFDVMKSALQLREKHAFRQQFHYDQLNIGMNTLQVELKKGYVHFLENAVDMGKCPILLLLLKYFKPHFSGEKTQLKGMGAMDGSSSLEDTRRLCVYLMDLAVEAMEENKADGVVFLVDLDGLAVSHLETQLVTDILQVLKTRYPEVVKYVLVLNGSAFTRGITHLLTKVASERTQQRIKMLQSPSDLRHFIHPPSIPQMYGGGYRLMTPLDWMKLQAEIEEVDLESQAPAQQEQQYMTKDARQLNGMQYAACSVDEVIEMKTSVIRGPLYRNKSGVSWAKLYGILRPEALLLYENVTSKMPQIIIPVNDETHITAAHFADAPRGTFGFRMDVPGMAGGHLLAACSEHERGNWLHEIQMGIDVVRDEHAREQYEEEKKLEEERAFAKLNMISFDDPPPQPSSVPKQHQSQPPAPVQVMPMMPPQAMGMPMKQQNPAMMMQMGMPMQMGMPPLPGGFPMQQQGMPMGMPMNMMMNNQQMYPQQQQQGFYQNTMPNYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTR7</accession>
    <name>A0A8K1CTR7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTR7"/>
    <dbReference type="OrthoDB" id="68301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="91" mass="10166" checksum="7791E5239B35ED72" modified="2022-08-03" version="1">MTQTESNTVPQVSAHFPRVPADCKKVADKFFSCFYEHGKQDKDSTDPEAGNKALVQCASAVQAYNQCVDVAVKKAPKKLFRVPEAYRVRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU03</accession>
    <name>A0A8K1CU03_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU03"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="211" mass="25635" checksum="45EC84B1F0E6FF0C" modified="2022-08-03" version="1">MQRRHWLRLAWWKWHRLVRMERLEEELIAYRCVLWTHRIDKLIERQARRDCRVILAVTWVRWRHWHRRQRCSAWRRGLTLAMRRCFDAWKRYSATLRLQSIERRELVAVIVGEIINATLTLVEKPSVESQSTRRDLLLMKWTQAASQQALAASFSHWRSMLKVVASPTAKLDDICAPMSSRKKLSYPQRFALEYKTRRRAKPTRPHRPAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU64</accession>
    <name>A0A8K1CU64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU64"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF18">
        <property type="entry name" value="OUTER ENVELOPE PORE PROTEIN 16-3, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="205" mass="22489" checksum="AF69256932E3F99F" modified="2022-08-03" version="1">MTPDLRVLRPLALPLSRFRASKTQQNAQTSEYRVLATSSKHTTTDCVSSTALMVYRGVGAGIAWTIAVDLYALVSASDRAWQEHLDTLTHPSTKARELRRLLLRTCGRNVLMFGGFLAVFGGLTCSLELVRGRHDMVNPFVGGFASGLVIMPRDLYKAPKNVLLGSALCGLAAMSLYQYIPASSQGRVETETETEQRELRPGVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUJ2</accession>
    <name>A0A8K1CUJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUJ2"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07573">
        <property type="entry name" value="CPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="38"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="321" mass="35324" checksum="095371AFEC40BB91" modified="2022-08-03" version="1">MSMHGGIRPGSGGNSMMGGGPPPMPAFKAPAAAIERIVTVAATQMSCGNPEENIKKAESLVRIASSRGAQIILLQELFQFSYFPVELNAGNFQLATTLEESALVQGMALLAKELRVVIPICFFERYRNSYYNSCAVIDADGSVLGVVRKMHIGDRLGYNEKYYFTPSDDPIKVWQTRYGRVGVAVGTDQWFPEVARALVLQGAEILLYPSAMGSNQYDPSYDPRDQWQRVMQGHSASNMVPVIASNRVGTELVDGIQVAFCGSSFITGQTGEMLKIADRESEGVLVESFDLEKFHIRRASWGLVRDRRPHLYSALTTRDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUR9</accession>
    <name>A0A8K1CUR9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUR9"/>
    <dbReference type="OrthoDB" id="121753at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="404" mass="47271" checksum="D62FE0F830DC64AE" modified="2022-08-03" version="1">MRKHYRAWKEDRTDRHCHPIFTCIDGCGTGKSRLLDEFPRLLQEELVYPPDCEDKESMQAMLRDALVFKISFSREEVYWPVTSTVGSRMLYQLQDAHEWSFFSRFTERHMTPEHALSLLSQQLEKPRDEMCVILCVDDLQCLAQGTYNGSQMDDMEDGEELFLKTMSSLSLLVNESKCWVTVICASTSFTPMYEYQVRTSQWRVDVPTRSLTHPMVNGVSIFDEFSMEDPRLMDVLIDDMGGFPRVLAQLYHILDSKSKSHNTSTFVFRSVYDFVVQDFQVKYRMDGPQLASMRLAFLAVLRCDSVAHLSRFGDLVLDEVLACSLMRVQSDRLVCPYMLYVLLESSRWDLSEKYLPRAERIDRTPWMTWQEFNIKFRVLKSLAWGVVNDPYLRWGKSARRSAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVK1</accession>
    <name>A0A8K1CVK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001894</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVK1"/>
    <dbReference type="OrthoDB" id="46760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="210"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1246" mass="139490" checksum="6A3D68AD96F9EF96" modified="2022-08-03" version="1">MSSGPSQYGKKLRAAAQERNLSRVKKLLKNGADVNASTEDGRTALHSASSFGHSDVVGLLLGHDACDVNALDKDGRTALHWASRHGHSDVVRLLLGHVACDVNASTKYGRTALHSASSFGHSDVVGLLLGHEACEVNALDKDGRTALHWASRHGHSDVVRLLLGHVACDVNASTKDGWTALHHASFKGHSDVVGLLLGHVACDVNAFDKDGQTALHLASEEGRSDVVGLLLGHGLNPNLQTKDGETPLALCFQLRRLDWERDKEKVFWNALETAHALLSSGAMYDGPPEVFPSVKEVHKDRAAIISMCVRRWTQEQQRKKRSLTAVPFEVFQRGSKAVETYLTELDASDEKDLVWRRKVCVVGSSKAGKTSLVKSIDKMTPTLEKEDDRTVGVDLFRLEFTEDVKSGSTVEQTSHAVTFWDFAGQDEYHVAHTLFFSRRTLYLLCVDVEEFVEVVRQSDACEDEDEAESLVLAFVQERVWRWIRLIFARQPDAEFVLIATKTDALGADAPSRLKDLERELFTAVTELKQTYKREIQREIDALLELSANDKTESSSDTRIESLRALQVQLESSVPTSWTGLNVCESSSIQRARTCIEDVVKRSGRSFAMPDKYSRVLHKVEELRQKARKAKMKTRIRQSFVSLAGLVQALMADIHDLTEDDAITILEALHDLGDVLWYARDGHHMLGDTVILDPELLIDFIRQIVCHDPAKISGENDPSDGQNDPLIQAMNQIGTVSNELLRHKFSWWKRLAYPDQLLRFKLLLQHFNLAYPASGDTMQADSDLIVPAYWRLREKQVDLGQLKPLSITDTEPSQVKTFLWEYYLGDNSAEVVDTVFQQLVVRSYYVFPNRAINGLYVESVQDGRLAIRIACGMVGSRGPVIRLQVLGKEDHDPSGWLRDVHEAIEAVLKMFPGILVTRKAVADSVSCNLDDCIPRWRALPDNQREAQLHDHSWLPDGVIDWFRRTDRGVRSWYISPESIVKRGPAFAEGGFGKVYLAKWQHTDVVVKEVSTSEMHQFLGEVTLWCDLRHPNVVQFLGANDQTKPYFIVSTYAAKGELLRFLANEKKDERVVVWRKLYEAAAGLSHLHRRDIVHGDLKGDNILVGKDGTAMVADFGLSFSESGSSSVVSENKDTLGAMAWRAPEFANLTVERPTRKSDVYSLGMCIIEAVTGEKPWSGYTSDEIREFLRNGQVKVDKPAVMTDAQWELVQQMIAPSPVDRPDLSAVMAKLEEFADAEQKEEDAQLCPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9E8</accession>
    <name>A0A8K1F9E8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1F9E8"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="61"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="39323" checksum="EDF76C6F101C1852" modified="2022-08-03" version="1">MLSSDMFSGVIYQTVVISPAISWILQPGRFSKRQGFFYAVAFLVAMAALAIGVEFSEQASNFYHIVGVPRDASLSDIKKAFRVRSVELHPDKNPSANAAAEFTRLRLAFDVLGDSEKRGLYDLYGEGAIDKARDALKIETMIQALSFYGVWAVFSYVLTLSETARDARAWSYVGIVVLFIAELNLQFAGASLPPSFFPFMTIHEFTRMLRAAFPLYMNGTRAIGGYFYRDVAQENLMLGVELLKSNRAILLSMRELQGEVASSRRRVEPAKNVKADSLPAAARKRLKFDKASQSAINSSIAQGAKAEAEAAAPDVDTWNPEAEVPQPAVQTPPQFQIPGFVYFIVVYFALNYLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBW6</accession>
    <name>A0A8K1FBW6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_014308</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBW6"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="280"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="49550" checksum="D1A665D8F5A8EC00" modified="2022-08-03" version="1">MLRGGVGRISRRWGLVRTMSSSIQWREGSEGVREVSVARFNAFLQRVREGVSGVAKGTRVHVMIGNEAADADSIVSSLVYAYFRDYVAKEERESKLFVPVLPIPRDELPLRCDVVALFQGLHIDTSSIFFVDEFPWRHEAFQSKEGESSLHMTLLDHNALNTKRIAEGLVAEDIGRIMEILDHHMDLGKHLEAPAREIAFQHDQALVASSCTLIAEKILAHSATKKVDEEVLALSATMLLGVIALDSINFDPSAKKVTPRDVAAANHLEAASFAQKGDLFRWLQSEKFNVAHWSAFSLNNCLVCDYKEFQLPEGSSGKYGVSAILIPLEAFVTKAKTGDDFVEQLQAYCEKDDLAFLVVMTMTVNSDGDRKRQILFYEANDQAHTKRCLQYFKSNDVLQLESTGLPYEFDERVSAFQQHNTGASRKQVVPLIQLALGTVAQVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCQ1</accession>
    <name>A0A8K1FCQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCQ1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="104"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="469" mass="53737" checksum="1910978DE8AE9B99" modified="2022-08-03" version="1">MGIERWDDDYEYAAHQPQTEQERLMRVVHGVQCTSRRFDENSRQNVYELYAHQLGEQAFHMHRPLDYFATAARDEEEETKSEIEFENSTSNYLVAVFFDPTRHLPSNEPIALTRTGLVQFAYHFAQSRSKKRGESVVSVHPVVFRTMDRAQLTHHLDDVQREQQVLQALRPEGFRKSRPYAFGRVEHVTFGRAYDHFPQWRFLEDAYNQYLLTDFAFNGSLVQYAAKRLREFSIEVAHLAGESRILDGNVVMKAVQHLWREEALSIFAGLARAVSYMHANGVCHLDLNPQSIAVDAHVNPMIVNFSSAEPVGSDGLAALGRPIYCKAHFAPHEIKMHNRNLHQSPGVNGKSADMYSLGVLLFWLLFVSQGNNESGQWRVLDPVQQDPNWNGNLVDHIQDASAIHDQCVICLSHGTLDSEIAYLLRGLLANDPYERVSAEELGQLTSRYQLQGDMFERCERAFRNILTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDP5</accession>
    <name>A0A8K1FDP5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDP5"/>
    <dbReference type="OrthoDB" id="420389at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000030">
        <property type="entry name" value="Glutathione S-transferase S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="79"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21921" checksum="D326BFBBC99D0393" modified="2022-08-03" version="1">MPQLKLAYFPHPGRAEITRLAFIAAGIDFEDIRVTNFPEIKSTLPLGQLPVLTVDGADFPQSMAIARYAARLGGFYPSDPLDALKVDMVVDTLQDLAGPIMEIMMRTPDEKLKAEKTKVVQEITLPLVLGFIESRVEGKYLLGEEMSLADLYLFNILSYVVLRLFPTYDFSAYPKTIAIVDQVKLHPRIAAYLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDQ3</accession>
    <name>A0A8K1FDQ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16293">
        <property type="entry name" value="CPSF2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000008">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035639">
        <property type="entry name" value="CPSF2_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="9">
        <location>
            <begin position="1545"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="69"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="223"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1803"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="450"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="720"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1805"/>
            <end position="1821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2039" mass="228166" checksum="34D7390207A76F92" modified="2022-08-03" version="1">MDQTPEVEVDVDVLLTELKRAKDKELRLRAEKERVRKELEAIRTGDLWTRESATQRELEDIRLRKQLVQQKEREEAERLGGLTQTLKEKELTAQQNLRSKSKTSLKQAASSIIGGSSTSGSSSDHQQEPGKPPEASVNQSSAEIKPPRVSSSVRLAELSDRSKPTDSKQSSSADRVIATINLSEQEQRIQTLKEALERSASRRDADLSGLPSMYADRTQFEVTNDSRRVSRRVESPLPCHGTSPSVVSRTKLDADPKNASPTQDHALDCGGPRIDLISQSPVQVPVGSNVPPNLQVQSHQVPAPTHYQPVNCLPTVYALPWMTPSVMMPTLPPMISPYSMPYSPWATQSPTFFVPSYQPGLAQPPPQFTSFPPAQAQKISELEDHVNYLRNEELRAEDTKEYSKIEVLLSGLKSQVDKMARSESTETFHEQLNDDAETNPVCETGVRALKRQHMEAVTRVQNERDLLEEQEKLEELKDRVERRRMEREQTRRHEEAMVKQKNELMMLRLQRAVAKSNVNGEVSVSSLATLLQGDHSYNPDQGIVFSMDCATALPLSIEMTKLSYAIYDGTIGQTSVKAIEARECEAYGPKRKRCVFATSRLLKNLPMSSDLRAIFEVSTWQQSLSTSQKPTTRSLGWTVLDLFRQKDRQLVLNSGFFELHLCAPPMPDPSKVLLRSSAGESDGEMVIYCRIGPGNLEEAMTRATIDPDAHVGLYHLPNQGLGSDQGSEASNQLVQPSTSTHNTANDQVVSPPDRADTRDFLDVERLRLLSSSSNRPVSTYSRSVTTAIKDRARLQAVDERASETISDDVWVRVDKVSERQKRVISNTNFQPGDAFNVFIDGARCLPESATVVKVTVAALNADRSRVPTENSSQIVLSAKDTRSPSFDLCVEFRERSFSPRLTLVVRLDTIDLYSKLPVILGYAVVPAFLDQETVQQPSRASITQFVLNEGGFQLPLYTSIEFSDTKEFDATCTSTFPRIPCATILLRIKCAAMSKDGLTILSRTQCPREEWAQHGLLDPAPPYHSGYYDSTVCAPTAIETKMYQQLEQRKPISCAQVLERIGLTESMVDGSLKTKPQAFLDLRTAFPYHSELGFRVAVDGLHNIKAKPGTFFKVMFSASPPASFYQSIRLTSDVHFTTSLDWSSLPTSPEFMDGFTTFRDVSPARSFAVIVDVRVLTRASKTGVFTSQPFAWSFLPILTEQGTVATGNFQLPLFAGPVILSALESETLSIYALMDEIGSEKRKTQLPFVDGASVFVRLEDPQVPSTTRMQPMVNTTISKMIPPKFSLKYQYDSVKAQDEARAMAVITFTPLYGVRSKDRCCAYVLEVDDVCILLDCGWTDEYDEELLKPLARVVERVDLVLISHPDLAHMGALPYAIGKLGLNAPIYGTLPVHRMGQIALYEAYLAKSKSDGEFDLFNLDHVDAVFDHFKQLKYSEKLTLTSSGEGITITPHVAGHLIGGSLWRIMKETDDIIYAVDYNHRSEHVLQKTILDSFTRPTLLITDSMNIHTEQPKLKDRDSKIMVEILKTLRAGGNVLIPTDSSGRVLELMRVLDQYWIQNKLRDPIALLHDMAYYTPKAAQAMLEWCNERIAKNFDVGRQNPFQFSHIHLIHTLEELDNLPSPKVVLATSSSLESGYGKELFLRWAPDPRNSIIFTSTMPPNSFATRVLEVIKDESGDRTISCVVKRRVFLEGAELALYEAKERRRLRVEAENKAKEMEEAAMEDMMMGIEDYESESEEESVATKETQLRGTFKVGLGQIASVRHPMFFAPEPKIEWDQYGEIIAPDDFKDMSLAINRQARKTVTEGEDGDVDMEEEEEEVAVDTRPTKTVTEDVTLMISARVTHVDFGGLADGRAIRNCLSNVKPRKLILVHGTEETTHELKRFVESTINACEAVFTPNALECIDIESDTNVFKLVVKESLYTSSVFRKVGTHEVAYVTGEYNIGENNALPVLQHPSDSNDVRPTHEPILLSDGKLKLDVMKQVLSKAGFNAKFRGGMLVCNDGVVLKRAMNNEIIVEGALSSSYYKIRQLLYDQFTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE12</accession>
    <name>A0A8K1FE12_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_007081</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE12"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000066">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222:SF76">
        <property type="entry name" value="MYCOBACTIN IMPORT ATP-BINDING_PERMEASE PROTEIN IRTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="138"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="328"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW58936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="572" mass="61759" checksum="464610A968AA6618" modified="2022-08-03" version="1">MSEAQEVDVYASEVNSPYAALTTPSNRNKVDTIVDIEVESEKEEKNQVSIAELFSFADKTDVLLMTVGTISALGAGVDISPDEFRTKANIVSRNFAIVGGAGVVGIFMQSACWATTAARQAKRIRSAYVRAILQKEIGWELALITLAFTPVLAVTTFFMMKIAARATQESIEAYVRAGAVAQEALSNIKTVHMFSAMDSFVTKYDNSLQGSITAGIRKAISGGASKGVLWFCTYSMYACGMFFGTLFVLNDRRDGCTGDKCYDGGHVLTVFMAVMIGGMGIGQVAPGIEAFTAARAAAYDMMKVIKRPLPIDPFSLDGKKLGKVVGQIDLEHIRFAYPSRPNSIVCTDYSLRIAPGETVALVGPSGSGKSTAIALLERFYDPAAGIVRLDGTDLRSLQLPWLRERISLVSQEPVLFAGTNGENIAMGKPGATREEVIDAAEKANAYPFISNFPQGFDTDVGDRGAQISGGQKQRIAIARAILRDPDVLLLDEATSALDNESERIVQESLDQLLKLKKRTTIIVAHRLSTIRHADLIAVTKDGEIVEQGTHDQLLSLPDGVYMSLVAKQMGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE52</accession>
    <name>A0A8K1FE52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_003524</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE52"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="51"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="296"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW57599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="54990" checksum="E5B60AFF53456CDF" modified="2022-08-03" version="1">MLLLVSLLATAYPLFLLGLLVLYVSKKRRIYAHHRRLGRTAEATSDGRMLTIGIFHPYANGGGGGERVLYCALAALVKRMKQQSTAKTLRLVLYTGDDGLDAATLIERSAERFNLPELRALRVDSFLKIVTLTKRAILEPSQYPRFTLFWQSVAHIRLALEAFAAGEKMGLYPEVWMDTTGCPFSYVVAKGLYACRVVAYVHYPMISTDMISKVQERTTGFNNNSAIAASTSRSYVKYIYYRLFAGAYGVLGRTCTDVVMVNSTWTYNHIKTLWSGSPIIVYPPCGTMEEFMAFDVQSREPLALSISQFRPEKNQLLQLQAFKVLLTKYRTQVQQLCPNLKLVMLGSCRNADDEERVVALKEQCADLGLTQSVNFVVNASFAELKKYLARSSIGLHTMYNEHFGISVVEMMAAGLAVIANNSGGPSADIVKPGTGFLALTADEYAEKMLEILQLTAEEREQLRIRARESSHRFSDDEFAKQLITALEPVLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEW0</accession>
    <name>A0A8K1FEW0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEW0"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16494">
        <property type="entry name" value="RING-CH-C4HC3_ZSWM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039903">
        <property type="entry name" value="Zswim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540:SF3">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540">
        <property type="entry name" value="RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="131"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="208"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW57047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="367" mass="41582" checksum="1851A06524B406F9" modified="2022-08-03" version="1">MEETLATTMYLVQTTGPTSYVIQEQNSEKKHKVLIGALQTCSCGELDVCIHILFVMLKVLRVPATTPIVWQKSLIDSEVEALLRGYYREQSRPPPRPIHASLKRRKDAKGGAEPETDNESAEAERHALVPGEVCAICQEDMLDDQPLTYCRKGCGNNFHIECMKVFGESRKQSKENIICPLCRHDWGDLALTALKKEIDVANRAPNVHKGVGCKKCQTKPIRNERYRCVQCKNTDLCDRCFKMNAHINHAFVMKKMVADTWTPALRSHQKRQAIGSDLVEELQNRELTTNDYDLLLQLDQREKYPIQDYLLSVLGGQRVLAANVKSFGDPNAMCTLCRQSLRIQADVRSILCGVRRVVRKKTDRGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG53</accession>
    <name>A0A8K1FG53_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG53"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="651" mass="71307" checksum="74E4C2B506EDDE0F" modified="2022-08-03" version="1">MLATEPEQEEATTTTNERESPVPTDVSTVATSDEMPNTTKDKAVRKEELHTLLPLNGEDLPTPKYKSIILSVCSFILVTEFCERLAYYGLTGSLPIFFKKNLGINSVLATELNNAFTSLSYLTPLLGAYVADKHLGRFSTIVSFCLVYLAGLALCVFASLPSVASQPLFMLGLFGGVAFGAGGIKPNVVVLGADQFNIDIPAQRTEKDSFFNWFYWAINIGATFSYGVLTNIAVNGVPPYIPQEYGFFASFFIPSLFFVIAFIVFYGGKERYRRMPPKGSALSSFFVVLLEAGGHSGRGKLVLSGGFAFFPGILLTTISYFVDEPTWHMIFALSGAGCVMYGIVVLIFTGNSTEWVRLASRAKGGSFTTAQVNDVAQVMRLMPYLSSIIIFWAVYGQQSSNFVLQGCQMDLRLSRGGDSTTLISSAMLSILDSGVILIFIPIFDKIIYPLVSAMGIQLTLLRKIGAGLVFSLLSMVVAGWIEQERKRTSFVSGIGSNCVNDDENLPMSNLSVWWQTPQYLLIGISEILTSISSYDLFYSEVPESMRSVCQALNLLTTTLGYIVAGALNSIFSFWITSDLNDGNLEYIFYIMALLVLLNVIAFMMVSQSFEYHVPPPRSEQIISGFSPALPRAARTLLGKLKPGRNGHTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGD8</accession>
    <name>A0A8K1FGD8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGD8"/>
    <dbReference type="OrthoDB" id="7785529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="190"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="37959" checksum="0266EDAA8EC5C334" modified="2022-08-03" version="1">MGHFSQKLKIGGQGSLDVSLDKTVFKPGDIVSGHAHLVVDQPITTRGLTVTISGWERLVWEKTDNHGNNPFKETLDILNDKVVLLDALDSPDGKMSLEACTRELPFSFKLPAEIPESFEYKCQRVRGMEGVRAHIEYSVTATLLVDGSLNADLKCVIPIVVEPSAPKNLRSQPVTVSNHDTVKYCGLFKQGGIYTEVTINSNVLETNSIIIAKVAVKNWSKRELESLRLCLVEDICIDRHRKRFNRKKSNSRDVCSRVYDKRTLESMKSDSNAAYELHLPVALNDAFQSGPLLPSMKSHFIVSLGYRVVLESKFNRGRRTKVDMPVTVARSTLAATGTTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH43</accession>
    <name>A0A8K1FH43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxypeptidase</fullName>
            <ecNumber evidence="2">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH43"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF201">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="535" mass="58643" checksum="8A2CA3BEB2249262" modified="2022-08-03" version="1">MDAKGKYTPIGEVPLTHRYGITSKHIKYAKYALGFVATLVVGHLAISKTTTTPLRSDPAIQVVTKANTANATYPGAGDLITELHGKPDDYTSRLFSGYLPISNGGQAFYFFAESLSAKPEDDPVLLWLNGGPGASSLAGCFTENGPLLVNEGGQSLRVNEYAWNNNANFLCIESPVGVGFSYNISGVYESDDLKQADELYGALQQFYVKFPWLRENDFIISGESYGGIYVPATAKRIVEGNLAGDEPKINLKTFAVGNGVNEFMTLSKVVYAYYHGIIGTEEYRLIRQACPEMKDFEPVDTGNLSPKCSNAMSKFEEATAALAVNSYDIYGKCFGNPLDGMDELVKELKERQTGFPHPISLPLSVCLDFKTVHTYFNIQAVRDSMHANKELTSWTNGVLTSANMDVGELAESFGLSAEDALSKVLKYNATLGNTVRPIWKYLLDHDVRAVIYHGDADMQCDFIGGLWAVESLQLPRKQSQQAWSVTIDGSEQVGGFYVDFGALQFVTVKGAGHMVPQTNPVEGKKMLDKFILNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHM7</accession>
    <name>A0A8K1FHM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013632</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHM7"/>
    <dbReference type="OrthoDB" id="3364966at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF21">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="98"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW61169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="267" mass="29422" checksum="E4D4E845EBAB5263" modified="2022-08-03" version="1">MTTTNALVTLAFKLVGIFGAALAVTLSLCAYLVREVHETDARLGLSTSKLDALSIRSFSSLAELQRSHETFVHIFHVHYGLAVVCFASVYVMKQTFAIPGSAILNLFAGAVMPLYIAFPLVAILTACGASFCFLLSRFLASEAIVVGVCDRVLPNKLQQLRHEIDNARADGRLMFLLLFLRVFPFTPNWFLNLASPWLSVPLHHFTPSVLFGLMPYNFITVQAGAMLSTLQSTRDMLDPRTIGSLVLLALGMLVPMLMKRQQKAKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHT3</accession>
    <name>A0A8K1FHT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-aminobutyrate transaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012867</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHT3"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000013">
        <property type="entry name" value="4-aminobutyrate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF79">
        <property type="entry name" value="ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="45122" checksum="0C76B0562A854CE8" modified="2022-08-03" version="1">MGKTHLMRGVGRMADLVMTKAQGSWVYTADQRKLLDFTSGIAVTSLGHCHPRVVEATQRQVATLVHAQVNLGYHAPMLELSDRLLPKLPQGLDSLFFSTTGSEAVENAVKLARHATKKPNVIVFQGGYHGRTLGAVSLTTSKTIYRAGYGPLMSGVTVVPFPYPTHGPIFEKESCGQWCLDQIKLALKQQTAPSETAAVLIEPVLGEGGYVVPPKSFMKGLRKICDDNNMLLIADEVQSGYGRTGEFFAIDGHFDVVPDVLVMAKGIANGFPLSAIASRKELSDSQPPGSVGGTYAGNAVSCAAALATLDVIEEENVLANVNKRGAEFMAGLQKLKASGRYPIQDVRGLGLMVALEFDLKLAPVGTAARVSEACLKHGMMVLTTSTFETLRFMPPLTISADETRLGLELLERALEDTFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FII4</accession>
    <name>A0A8K1FII4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FII4"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03001">
        <property type="entry name" value="PDI_a_P5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035453650" description="Thioredoxin domain-containing protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="430" mass="46748" checksum="BB9C1B21B0A5EA77" modified="2022-08-03" version="1">MTMTRRLVGAVCVLLGVSALVQAEYGPKDAVTVLTEQNFEKEVLNSPDFWIVEFYAPWCGHCQKLEPEYKAAAKKLKQQARLGAVDATVHQSLAQKYNIRGYPTIKEFGANKKKPRDYQGGRTRREIIDYVKNSEEAKKLGVSGATVVSLEYNSVHTFLKQDEKTPSAVFFGSKKSGKKKASAPPSWLSSLAQQFMKGKKKKKPTVNIGFVPGTEGKTAKHLGIQDEDLPTVVFVDASGSKLLKFSGSDLKEATAKQFIADNVKATQGAVESWSSVPLFPAPEVAKKAPKVALNELSVESIGACVTKKGKMCVIIPRASESGAGTEDDKIKSLAKRYRRDPFKFLSTEQGSPLFGKLTSALGATGANVLVVKPGRKVKFAAHTGATDENALTSFVDKLVEGSAQFEAITLTKEELEAKLKEDVKSTHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIQ4</accession>
    <name>A0A8K1FIQ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIQ4"/>
    <dbReference type="OrthoDB" id="152248at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454131" evidence="2">
        <location>
            <begin position="24"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="258" mass="28520" checksum="A63816D51C6EC42B" modified="2022-08-03" version="1">MRRLLASLTTVLLIVYAIYCVDAHGPRGGHRPHRGRGRKHPAFDRNGPHRPFRGGRVRRPKFEGEGCPPSTVELVNVSDSSTFLLSALFSNLMVQTTTESTFERKHCVVTVILEPQQNMSIGVVHVDFRGFAYVPSDDDGAYARLKSWYNLGRKPRQLISNATYAPGFEDDIYESVDITTNMWTPCRRDGKPQDAIEFRINARLTAVKSSLDGDDVILAVDSSDSGLYYKLATRPCGPDDDSSDDVPVSSTSPPSIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIT5</accession>
    <name>A0A8K1FIT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014543</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIT5"/>
    <dbReference type="OrthoDB" id="45753at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="217"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="724" mass="80607" checksum="88FB994C9A8026C9" modified="2022-08-03" version="1">MARCLHVRRLRASTRIRTPSTRVHAVAPASALALTWRPRRCDCNRRLLTHWIGGAADSSPDPHEDHVVDTGLDFVGAAEATARRTLQASDFGADMLPALNVLAESLQMVQQIPAFQNWTSADWLLGLTVMAQHNTVQRRKKRREAAMPSAVLSPTHQTSVSELLRYVRICDAVYADTVEGFCEEAHLPLETIVRSHNGGVFSPKFILVLDHETQEIVLVVRGTASILDFCTDLCLMNEPFQDGQGHRGMVHTAQWLVQNVRPDLERLTQEHPEYALTITGHSLGAAVSALAAIELRPSFPTLRCIGYGTAACVTQNLAENCKDFVTMIVNGDDCVPRLHQHSLLKIQTEVAAFDWRTALKQMVAEEVEEQKTLAKKKRDEQMEQIHEAFERLKRTQQEQARAKLSTVLASPVGKRVSASLEITKAAFGTEGQPALERIASVKEVVQRHKSDDKIWEAIETSVEGLELVASAIKRPEELRALLRRSKALLASTIANDEDAKRPSQGESTAPESSKDIPPRLAIFKDRLTKLVDETAQNLRSGVKDKIGVVTETVTTNVTNLKVEAEAVIKVQTTRVEEEFQEIQQNVRSRAEELVRDVSETTIAGVPVRSLLSEFEIKSNETNQHETPEQLVENVETETAPVPELLHDPLFPPGQILYLHRVTREEAASSTAIAVTDAVELVEVPIDEFSRVLLSNRMILDHLCTTYERVLKTMDTETPPSEMQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIY5</accession>
    <name>A0A8K1FIY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIY5"/>
    <dbReference type="OrthoDB" id="161258at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="355" mass="39842" checksum="480585D137541A03" modified="2022-08-03" version="1">MQCVLKLSFRGETHRLTLDQHEVTFKELEARVNDLYEEARRPKSWTLIYRDNEDDLVTVSNDEELKEACHVFAELKESTQRQSNKLHLHFHVVAKVTLKEQLAPVIHAVEEISGKVVRLAADTRESIRRSSYVEKGRESLATSAVHTREALSAAGRGISHRIRRASSAASEQISGIRERVERRRSRFSSQDMVDVDDSSPVALMATDVERNIEDDVVPDLMPVEELLAQARAAEQAESEDEATTDAQDDDVDEEMPHLEPVAPSNEDHVPASDAETASTGSDEHENGWDVVSREPHSPIFGVETDDEMEAYFGGWQQQLQLIHGIMPNADTAICIDLLEKHHGNLEAVLLELTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK12</accession>
    <name>A0A8K1FK12_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor Tu, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK12"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="139"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="569" mass="62978" checksum="312A09926E76D26B" modified="2022-08-03" version="1">MDRIRELCRQVQGEYKRRPSKNEDVVASTDLPQEVEEGNVEYKLQLLDPAPDRVKHLTTQLHWRLNEGKGEAFYEIGVRDNGEAIGIPLPSMIKSMRTLARMCQVLNASLEIVCFRQGHEPALRAVRVRVTRIVDKKAKKQLRVSVIGDFESGKSTLIGVLTRGCLDDGCGLARMQVFRHRHEIENGCTSSISEHTIGVTEDGGFCTVDSYDDCDLRDSDEPAEVKSLITFSDLAGHKKYFKVTASGLASQFPDYAMLLVDSTKGVQSMTIEHIKIAIALEVSVVVVLTKVDNATTERIAETILQVQELLKSLAPGQTVRLIQDGTEDVSAREIPLVLVSSVTGEGVPKLQSLLASLLPKRIWSTQSATAAEFQINKAYDHEDEGTIVTGLVQSGTIVVGEHLLLGPDSQGQFSEIVVNSIEVQRKAERSLAAGETGALLISRTSTNEEPMAASYIRKGMMLIHPSVEPMATLQFDAEVHFLQDLSLLKENCQAVVHAGRIRQMAKVVRVEPQGHSPRALCRFEFMYWPEYMRPDIPVVLREASAYAVGKVVRAVHLTNEHTPTTVRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKK2</accession>
    <name>A0A8K1FKK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKK2"/>
    <dbReference type="OrthoDB" id="531564at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14223" checksum="53641867C40971B6" modified="2022-08-03" version="1">MNMLPTALRRLATRPTAAAGRRFMGAGGHGHGHAKDYPFGMHFHVSPVHKNLALAYGTMLWLWIFWRAKQDGKVVLGLEHPWDHGHGHDDAHHGGGHHAPRGPFKYERTEVGERPTLVQADEVEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKP8</accession>
    <name>A0A8K1FKP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKP8"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF1">
        <property type="entry name" value="GH21943P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="56099" checksum="E95112AE88FDFB46" modified="2022-08-03" version="1">MEGETNAKISRNGSVPKMSTSAVYWQISALIGLSFLESFSFGIIGPMIPIVTTEYFARHYTNGEHIDCGLYPHSLACVMGSKDANWWSSIISAVGSFCFFVISPTLGQASDHFGRKPFIASSQLLRLGLPFSIMYFTQSNGSIWPYFALRLACNIFETMGIGSAAIADIVSPENRATAFGILFAAFSIGYCISAGLAGLFTRSQVLQICVAIFISRVLWAVFMIPETLPLSKRKKNKSRICKNPVRSLAILWRSKLFIRLTIMIAITTFVSNGLFQIRMFYLNTTIGFNEKDMSHLMLTFGILSIFAQIVLLKPLMRCGKEKGVIIVSIVARIIECAGYVLSAFVPKPWVIYATAPVNSIGDLSFAAISSLKSINCSEREQGRLQGAIYAARAVFEAIGPVVFAYIYNEMNQESKISMVLPFVISIALYGCGLGVACILPTRKPGAPPPMPFSPLSSAASSPGVATSVGTVDFDFEDDDDEDNDADIEEDDERLLNEPLLADHNNMDHGVVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH4</accession>
    <name>A0A8K1FLH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="2630"/>
            <end position="2665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2096"/>
            <end position="2169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2708"/>
            <end position="2731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2104"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2116"/>
            <end position="2133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2142"/>
            <end position="2153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2731" mass="307061" checksum="BE6967C0F19D67D7" modified="2022-08-03" version="1">METRPGTALRSQETKEDDDSYAFVPESLRHHFQRDLSRLGDPQDEETHAIDTARRTRSALLVSTLLYTTPAKARTSPSKRNAKASPKKIDKPGAKSSRQRTPPKAYGGSMSAPLYSMEIEQDITKRMTLDRAVNELEQFIGTLTAKIASLEAAESNAVVPRWLSDTRERAKVPTLLQLQRKIVQSVASCLPDCDVYLAMYEPLPLANPHAAVSTSLLRYVASSSQSQMLGEVLYRNPERPSLSFEVRESLDPALVMDIAEHEQQTLLRFTTDTVTGPFACLPLVDDTNAFGIGVLSVDACRKAQQTRPEAMSSTMLHEFLLRMHLPDAALEMRKLRFGGRQFLAITENDLMHRPAYSKLKFPTKKRVLQLVAALKSGLTIHLATPPVFFTSDNELLAFLDDVCERSGRFLDMYRRQVHWHRVLAARTKDVNTTSLDLFSVLLHSIANALISVDRISIWRVRDGTDIDVLGSTQIPDDRLMPFLQWSERHIRRVSLYKENEDAGGRLMQGSIIRIQSPSNQDDPENQQKPCERAVYHVKWSNRTQQSLSWPSLRQLLPIRPMNAKHYQLALLLRRLQKLTPNELKSKFLTLTDPNNAMVALLRDPMHADNDVVYAVQVDFRPQSPLPDPATAQRFLTRAVAITQHSLVCVRSRETRTFQRQLSMVRTTRQLNTMTLTPSMDALETLEAVVALVFQEISLNLPNTMQQIAELQLDGSELLYTFAANGSTLKGRTMSRGQGVSFRCIDTSKPLVVDATSDLRRRLRIFRPKDGETSATRRVEDELPYIFIPLLHDDVRVGVLSISWFTNVPKGREDEAHPEHGVVDYLTSLSKPLAAAIYLKRRSFALYQLQQLRKEPLRSPQQLFFHACRALKDVMIGVWKTRIVEIDFSRGKSTTIFELSDTERKRAESTHMMHVIPLGFRIPELLPDTIARHWGFSESQVRELIKSWHDYDDEEERQRLEYEAAFTGERVAQSGPMTNPEKRRIMEKKVRRRYERLELTEIEDTATKETTNAVALAAARVSNPKYVSHSLSIALSTKTIAYAPVTPLAIGSSSAIFLAVASLPQLFSSHEQAFVDRVTETLSLATEELLQRVERSRTRVRAITAFRLECQTAVEEIKARAGPPSEDTRSSVFPLSPSEELRVESLLDLQQRTIRLISSVLWCPYVYIGLNEPFLRRIRYTAATEKSLMRGKHLHRGHGLSFYVLDSQEAVVATGQALQDVEQMVGHGAKLRVFSQDTPKWPFIAVPIGRHGVLALDNLEKYQNLAGEAQPELGLVDFLRQVATHLATAITEVRRFTTQLRRDRREQALVRVMAACEMNSAVSTPLFLQLVVLQAIESAFNGVDAYIGMVQPLCAQLVFTSATTKSGMATQRVNTLDSVSFRVFLSQRALVVPQLERHFDASEQESARLVESLKWFTASSNGSHRKGPFVCVPIPFVGVLSVDTFPGAAGGNYATQFPEPGVLECLTAMANLLGDHTRRQEAADAQSKISKLFAGNRTTFTSLFDEILEAIARIVLSAVEFSVLRYDQETNEPLKPLATLCSPVARLEPSISSMESEIRTALSGQTESKERCFTLPSALEVVLMRCSPTRDVEDDEATPRTTVLVVRRVKGATWMYDLEFLQTLVPLIDDLITRVNTRVYGIVRRRVTFMELERQCFDLEAPTLSGQSALDRLPLLLTETMTTIASAISPYEAADVYLGERQIGGETLRFDAVSPLSLMKGVALEVLAPENQSMVVLQCLDKQTNAVVHLMDGKNEKELRQLTEKKPQRVYVAIHMGESRILCADSLGVEAFDVVHRRLEADVLRFLKDCATLLESTILSVRYRAAYEAMCALKTQRHGNLSRFFSTTHRVLRSEIGVLQSQQVMKLANDFTGQFEVVSWHRRPTQRPLKTMGQHFCSINGCERHHILTDVHMERHVALPMTDLPRTLDQSRSSGLPLVGKEKQGTYACECFATMLDSSLPSSRLALCVFSHERGALPSRGKPSLPRLPSQFSHPQRQFFMAFAAVASDVYAHVFRACVLETCSLELFFFLRERWNIKDGLVVTVGEHDEANAAAKVAFSLQPAKCPRGSSLTDKLAAKVLTFYASHDPMIMFVSKKKATPPSPNAKSAPAPAPSKTMTITEEANSTKTKTSRSVFKRPKLFSSRQAPSKTPASPSVPVKGMQQQVPTPPESLTEVHVLVRGYKSDVLSFRVALGLNEHIKRLEADVLQQIDTSQSIRSTFLASPQGDEEWNGAGYGDNRDLGDNGGGGGFLVLSAWKKSQERVRASIVHFEADVRNYLTGVQATSREQILSEKPAPSSRPVNSDSLFASADSEIIAAAVVVVRAALLLAGSKKELTSESTAEANQECMKEYLRVNTGRKLVDLDPRDQTKWASVVRAGVYLRTHHRAVHALFILESESSSATQSCSKLLEYQHALVSAVRYFKYLVDDAKLRRTAAYAPAITIQCFYRVVRSRITLKRLRVEYHAAVSIQCAFRQHLARRKLLFLKWTRAIVTVQRAYRRTLAQRRGHRPKRVNDELRAVVARYGDMQTTTTQLQRLPDDDDTWKVDMSAFDSFMAFEKSKAGREQFKREVAHLTERQKEIARQREEQLEPHDRLLAHVHDLFELLDTAGSGELSRATTLELMTRLHVPLSKDEADDVIDMMDNDRSGSISFGEFTNWFAHEYQILRRRNRDCGVLLTRDRQWLIEESARSALRKQWRAMKLGQASAGLAAPGVAEHGKGSNVVEKDDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLJ0</accession>
    <name>A0A8K1FLJ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLJ0"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016206">
        <property type="term" value="F:catechol O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="237" mass="26088" checksum="D706DE245975BD8D" modified="2022-08-03" version="1">MTFLASVYSVVQKVAGPLLRIDAKMQQSAVACLEYVKANAEAGNPASVIAAIDAFSKKNMMMNVGERKGEIVDEQIRTVKPQTMVEIGAFCGYSAVRFASLQREVVSGDSHYFSFEFSPEYAQIVQEIVTLAGLSNQVTVINGAFSDQHSVLQGKQVDIFFLDHEKTCYLPDAKLIVESGLLHKGSRILADNVLFPGTPDFLDYIQSHPQFKSELKEAEMTGRFTIKDAVCVAEYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLM6</accession>
    <name>A0A8K1FLM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding 8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014697</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLM6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF193">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="795"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding 8" evidence="4">
        <location>
            <begin position="589"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="979" mass="109474" checksum="032D8FC6291A6527" modified="2022-08-03" version="1">MTPAHTPPLPVVPEQTQWQEDADPIDPRTRTEQRIPAISTLPRLARDPTPDSRRQQQRPSDLASLHTARNIEALRSMQSSSFRRSSGNRPRRGSSGRGGDSDLHTGSSAGGNANAALYRGSEIDLMATCPSSWRSNGGGGDFVLDTSLSGRHGAQSGAETVELPDEDENAVAQNQRAARTAGLVWSMTMCSMLVMACSSVFFVSSQYFDPIAGTGMKVTFLEWFDTPLDEEETRAEALEALQMNKQDVATGHAELANPVYFSLFVACPVMISAILYELFVRSYEGSQLRALLRPLQWTRAPWRLFNGINNGEAIFVVVILLTNILVFVVALATQLHRVHKGWDVDHIPHKVDGLTSNEVHDNVLKAIANAFGYCGIVSISFVLLLSARPTSNFLLSDVFGLTRERGMVFLKGTAVWIGIASVFHVAFYINTYTNEEVFGKRFGYLLYSSDTDEYDNIAEEALNEWLHARDVYLGWMVFFGELAAICLTVLTVATVFSRVLRKKTSEVDQFVQKFCGIIGFFCLHLHYDSTIWWLYPSLCLVVVNLIHSRANGDTPVQVIDFSPLRNGVTRLVLAASHSLEQASKSRSGLAGRFVFVCLPSVRRFQWHALYVATSPTAASESITVYAKSCGRWSQAVYEHAKLCREKKSFPLVFVDGYYGNQAIDRVLSASHVLLVAVGDLHAPYALSIFQELLALYAAHAHPRHLRKVVLVWSTDNLSFMKEMEPMLRELKKLDSHGDIFQVRLYLTGKPCDEDIEAFPDRQPLSQFAEKQFGASRLIGERQPVPFQRALFSSTVYLIASKLVVVLGTALLLYSVRYQASGHEFWVLVRLTEVAMVFVGGLLGYCLVYAERRMIQTVLSFMNVDRYSAADVPATDEMSVRAERMVAGGFDVIGTYEFESGIGFQEEYSVRVNARPPQYEQLLDEMWKSSRKEDLAGDPVFQQQRTSCVEIAAPRGHDIAAQFRADQRQRMDLHIEEMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLP0</accession>
    <name>A0A8K1FLP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_012467</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLP0"/>
    <dbReference type="OrthoDB" id="64878at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.486.10">
        <property type="entry name" value="PCRA, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="17">
        <location>
            <begin position="18"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="18">
        <location>
            <begin position="315"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="729"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="734"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW67351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1049" mass="116316" checksum="A8A937D631D201E2" modified="2022-08-03" version="1">MAATVRRNGLCGRRISTHALSALDAVVRRPQGGHVAVVGTPGTGKSTAAAQRVLWLDTQSDRRVLALSARSGEDAKMATLLDRELAFYALERRGHNVSSVMEWTQRTLEELGHQQRVLPFDRLTAFLMHHIAEIPLERFHHRLTTPSSVHFRRSVADMLRFFNLLEAHYVTPAAYESFAGTNEETTAHLELAHAYRVYRELLQRHHLASWDSCVVDLLELLSKDPHYLSSVTNEFTDVVVDELERLTPAMVQLIGTIVRETPELQSSTTFSETIVADQNETTGCPRTEQLKSLLETSDASIKWDLVQLPPTTTQVPVLSFANAMLSSGGKTKRSKTKKQEFPSVPFPVESMEFATMLDEAKGIAQNLKERLVDTGIPPSSIKILCPTRADVTYITQILQEEGVPVQGGRQVSSTGSSSSLLFEEPGVNGIFSLLVALCCPSDTKHLYNVLRSDYLSLAPDVLSRIMERYHREATHACLLEVLQTIVDTNGNLLAATSEAEVASNTQAVERIRQFLDLLSECREACHIKTVQELVQLFLERTNFLSRVLDPDSSKDARDSIALADFLREIETAQRIVESPHVPFVVPYLLQLQSARFSVTEDADSEDVDNGVVVLPLSRYSLDKLDHEELGECKLLVLMAMRDSKFPGRMKRITWPLPTSLLQTPLPIQTRPQFLLENERLVYETIVRTTPERLVLSYALAASSVPSKKPEKLSCVLSPLWNHAESLDQPANLESTPSAASPPSTSAPSKKSPVATPASTMLSPYEPSHLSYSQMSEYQRCPQRYYLSRVLGLRTSSQEGETTPAMMYGRSLHEAIAALAQCLQEGKAVEAATSEAFEVLEGTWQRAGFLSRRQEGFFFAQAREALSRFIQNDNSSAEILHIEEIFECRLPGSDIEIRGVWDRIDRRRSDGAVIIREFKSNPSGQARPNLDLTAAQSLQLKLYMVAYEQIHGVAPHGASLEIIGGGDGSVGFLPYSPDLLDEVLEVVTSTIESLRRGSFPATPDFMTCSMCPYATSVCRASKEVATSLLAVDGDVDSDQEERTTSTASVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM16</accession>
    <name>A0A8K1FM16_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM16"/>
    <dbReference type="OrthoDB" id="101550at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="52979" checksum="DF3CAD5A796C5834" modified="2022-08-03" version="1">MLRMLRAMAVGGHGCYSEERVRAFDAYCQKTSRRRAFAVCILSPVPSLLYVIILEAAFPLAPPEEGWAANYNAWIRMYCAGIVLAHSLVSLGGRFVPDFQFPRRVVACTAIATGTIYILVCIGWAALWVYPLPFFLLLTTGPYMVIWATCFRCIVDTTCLRQVQNLRFKLLNFVKAVVWICALTLFYPAYTALCATQTGYLYVFITVLPTLLKTGMKAKLASYCRAVGQEDQISSVIQFTIEVFHSLYIINCVQLSTNAALSTLAFVLLDLGPSLLNSHKILRGARSVSPSPTKQIIPPVPTKPRLTQELGNRISRTMPGPVWRNASKITFRSAASRRVLLMCEYHLVYEFVESFIPVAYMIYLSILYHLPNRKYYPHMAALQTDADLHRMLLNISVFAVLETTSLIFFCRVVQRKLGMSGLFQLAFFLEDQCEMVQAWLFLWMPYCLFFTVKHGGVDFTLKFAWIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMK7</accession>
    <name>A0A8K1FMK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TATA-box-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMK7"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="28666" checksum="346050AFF11F2694" modified="2022-08-03" version="1">MATAARTSTRSRAVKERQLALIEDKTTDIQNVRDGEIQLDDDWEDKLNLQVKIMNVVGTVDLKTPLELKTIALHARNAEYNPKRFSAVIMRLRDPKTTALIFGSGKIVITGGTSEESCRLAARKFTRVIQKLNFPAQFTEFKVRNVMGTCDVRFPIRLEGLLNDHARFCSYEPELFPGLIYKLVEPKLTLLIFVSGKIVLCGARDSSHLHQAIDKMYPVLLQYRKMTAPPSLVTGKAAYEDAEEMERLEPNAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN42</accession>
    <name>A0A8K1FN42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparaginase</fullName>
            <ecNumber evidence="2">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-asparagine + H2O = L-aspartate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21016"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="EC" id="3.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparaginase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN42"/>
    <dbReference type="OrthoDB" id="427002at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009066">
        <property type="term" value="P:aspartate family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.40:FF:000001">
        <property type="entry name" value="L-asparaginase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1170:FF:000001">
        <property type="entry name" value="L-asparaginase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006033">
        <property type="entry name" value="AsnA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00519">
        <property type="entry name" value="asnASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="8">
        <location>
            <begin position="91"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="9">
        <location>
            <begin position="297"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="458" mass="49981" checksum="B8DE486798F7EA3D" modified="2022-08-03" version="1">MTDVNASEPRGVDAIVRTAAADSLASPLKSGSSSPLGRKLSNVSLGPTANVAPVPVLMTTTSSSAPQPSCGSPHVLTSHTTGVDAHERAKCLILYTGGTFGMVPDAQGVLHPSSGFLAKKISEMDEFQFENMPLVTVSEWDDPIDSSDMTPDDWGRIAREIESHYWDYDGFVVLQGTDTMAYTASALSFMLEYLGKPVVISGAMIPLHFPHSDARRNLIMSVMCAANLAIPEVCIYSNDKLLRGNRTTKIANMAVDAFHSPNFPVLASTGVETTVDQALILPYPRRRFSVFTKLSTNICVFHLVPGFDDECIEAYIDRHNEKASNRGHKAVVFALYGTGNAPLKKDNFLRLIERAIDSHIPVCITTQCVQGRTQLDAYATGVKLLRMGVITSFDMTIEATVAKLAYLMGKGFQGAELKAKMESDLRGELSVVDSFSDADDMNRNRQYRKTVIRNFATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN63</accession>
    <name>A0A8K1FN63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN63"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="305" mass="32658" checksum="B3D3A01F75484D96" modified="2022-08-03" version="1">MTESYVRVSTPAQEHHDGATKPTSEPRWKRLLFGVPGIVAGAIIGILIGYGLQEADASAEVVSWVGIPGTLFIRAIKCLVAPLVFSSLVVGMADMLAVGKASSIGWRTAAMYTITTIISSCEGLLWVIIFRPMFSNKSAEVADTTPQMAFQCDKPGYFLSHANDTVQCVFDSSYNETSEFSSSSIFFVNDVTGSFATSAGGFAELTLSETLQAQLYSIVPDNITQAFANASLLSIIMFAIPFGIAIAILPKEMKIIANVFREFVEVFMKMISWIITCTPFAVISLLASSVAGQEDLGVLVGSVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPB0</accession>
    <name>A0A8K1FPB0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromosome transmission fidelity protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014049</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CTF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPB0"/>
    <dbReference type="OrthoDB" id="121932at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605:SF1">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605">
        <property type="entry name" value="CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW66737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12771" checksum="D45A31C50FF5E63D" modified="2022-08-03" version="1">MLVPLRVDGATNEWCIVEFQGEMVPNDGAEMADVDIGGLWYDGGVPTMRIGNHIVTGKVAKLPKPFAILEKHGETTEPMSDDDGDSSSTETETPVEYNVVGIARTRVIFAARPKPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPK4</accession>
    <name>A0A8K1FPK4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPK4"/>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="383"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="162"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="456" mass="52895" checksum="21EDC257C1106C12" modified="2022-08-03" version="1">MDERVDWRVQVYWEGEDEWFEGVIREYDEAQGYYVCYDDGEEQWESAGNPEIMRFLRKDGQDDEENVVPLVVTPEDARWSNEPPPSSNGYEDDAYDDEYEQDDDHEKEEEEEEEETTQAPSAHSTTPEKDESRRQKPVKMHPVNVRDPTRYMGSDVVFFRDEETLRERKAAIQKELKAIKQEHEGLTSQLRQKEQHSTQLKRQLDDLKAQVTLSGFLTKSGTSQKPKTATQWLERVTQQKIQNRLLQQELTVQQSALQQKKARLLALEQQRDQLQKRLDRVPKKELCSLVEVQMEITRLLNEKRGLEAKLVSKTASAPSGKRDEKPRRQQELEIELRKHDQVVARLSDEVDRWKLSVERENARLAPLRARLTSLHDDLSKYASSKVLLRSAFLRFDREGSGTLTRDAALDALVLLAPPGAPQSREELARGIPNAATITFDMFATYFDQLCEPKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQL2</accession>
    <name>A0A8K1FQL2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQL2"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="19"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="35718" checksum="20024B39B8E0E00C" modified="2022-08-03" version="1">MTTPASYRAFQFTKHGPAATVLQLRTDLTPDALTSTQVRVKVHSAAVNPIDTKLVEDDATWLWGLTGISQTPPSEKNPYNVGFDAAGTVVEVGADVHHFKVGDAVYTMTPFDKFGAVTEYLVIDQAYVAPKPASLTFDQAASLPLAVLTSWQALVQHGNLQAGERVLILGGSGGTGSLGVQIAKARGAYVITTTSGRNADFVKSLGADEVIDYTTQKWVDVVSAHSVDVVYDCGMEPGSWNDEAQRVLKQNTGRFVSLLDIPDRTPSLIGATSCTFLAQPSGSDLRDVTELVEKSQVTPIIDSVFDFEQCADAINKLKTGRTRGKIVIRVATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRY5</accession>
    <name>A0A8K1FRY5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRY5"/>
    <dbReference type="OrthoDB" id="167531at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="348" mass="38922" checksum="DDB9FFCD0FCC39CC" modified="2022-08-03" version="1">MEASLKVNAQERDSKGRLKNPFLRAASQFPRYKLDDARTQDPNAYSAECMPAKTTFYGVEAKFDDITGDLLTSGLANGSVILELNEWTTHSLSTMTLAILAAEVYDYPVSLYSTEATLSTTERMSSAPAGLCTPTHVNLEVWPGMEALLQVYANESSVVGPIGYVAQSGLYTTIDFVKDSFDYVKYSELLNADFWRSYTVLDKLIDSVSYADFASSAYFPTGNAVCTDNTMGCQNYCFKSNACKLREANGKNCIVVIMMSPNWDPGYLQASMSNVGMPAYFCFLGFGGTQNYVLAMQQANKPVLFYHYEPELFHFNNPGLFQRVTSSNSRTSQVEQGHFRRERLWRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTH5</accession>
    <name>A0A8K1FTH5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001754</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTH5"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425552" description="subtilisin" evidence="10">
        <location>
            <begin position="21"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="175"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="461"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="462"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="537" mass="55573" checksum="2416CD9D092F4B58" modified="2022-08-03" version="1">MVSTKFALIAAALAISGASAAPRVDPSVHRTLRQQGTVNLIITMKDSNTEPLKVVQEASYATRGAKIEALVERLSAHAESSQADVSAVVSHESSASLFTSTRTFWVSNQRYIEGASAALLEKLSAVPSILEIREEQVLPLPKVTAAANTTADVLANEWGVTKVNAPTIWGNGNKGEGIVVSTIDTGVLGTHEILKGNFRSDHGWYDPEKKAAAPYDEQGHGSHTMGTIAGANGVGVAPGATWIACKGCRTDGCSESDLLACAEFITCPTDTSGNNKDCSKAPHLVSNSWGGGQGDTFYKSAVDAWQAAGIIPIFANGNEGPACTTASSPGDYENVIAVGATDSSDALASFSSKGPSTGGLLKPEVSAPGVNVRSAWYTSATAYNTISGTSMATPHVSGVVALLLAAKGDLTYAQVKDALIKGVDTSSLASTGATCGNTKDGSFPNNMYGYGRVNAVKVIDGSSTAPTPTSVTPAPTTKTPAPTTKTPAPTTKTPAPTTKTPAPTTQKPSTCSGLDFYDCYYSDNCYWSWSKGECADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FTK8</accession>
    <name>A0A8K1FTK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3,4-dihydroxy-2-butanone-4-phosphate synthase</fullName>
            <ecNumber evidence="5">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001844</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FTK8"/>
    <dbReference type="OrthoDB" id="60371at2759"/>
    <dbReference type="UniPathway" id="UPA00275"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000001">
        <property type="entry name" value="Riboflavin biosynthesis protein RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001259">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="11">
        <location>
            <begin position="228"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="40448" checksum="0C98338910BABBC7" modified="2022-08-03" version="1">MCLAPLAKPSTMNTTNAGTSSIEDALAWMQKGGLVIVMDNEDRENEGDLIGIAELATEETMAFMVRHSTGIICVPSHAQRLQDLQLPLMVENNTEVHKCKFTITVDLREGNTTGVSAADRARTVRALADPSVQTEAFNRPGHIFPLVAHKGGVITRAGHTEAAVDLARLAGSRPLGFIGEINDDYGRMLRRPQLEEFAQTHKLPLITISDLIRYRVRNERLVERSPTSSTVKTPFGVFEAYAYESQVHEHAQQYEVLTFGDLKGHSDVPVFFVEEGFHASLQAQWAQKQIAENFGRGVLIYVNDSKSLIEVSGELMARQSIFGLGMQIVRDLGAESIVLLTADADARLAFDPQGFGVSVERVEALTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Y3</accession>
    <name>A0A8K1C1Y3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Y3"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="611"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="69"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW54952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="640" mass="71144" checksum="12DCF88BC4B65C3A" modified="2022-08-03" version="1">MTITEDMCDDILALSEDVHSEFQFSSASVFGTKAPPTSIPTLGGTAVNMMEPMAANTCTLSWQHLSYWVNEDRVVWGSRQTRANNKKEGKRILHEITGRCGPGELMAIMGPSGSGKTTLLDILADRMRVGTLGGFVRLNGEERRSEVFRHISSYISREESLLGSLTVRETLLIAADLSLPIYMPRSVRDLRVETVLDNMGLRNCQHTLVGSLFHKGLSSGQKRRLSIAIELLSNPSILLLDEPTSGLDSAGAYGVVQCLVDLCLEWNKTVVLTIHQPSSACYSLFSHTLVLAEGKSVYAGRAERAVDHFASLGYVCSIYSNPAEHMLSLVNRDFDGHADVDELAQGYARSPIAQAVALQITMDWRDASNFPEIRADAGMTSGFAQFLVLLRRNALIAVRNPGMYWIRLAMYIMLSLLIGTVYLRSNKDITDLHRAAMIFYLQAFLIFMSVAVIPFFIEQRFTFVRERMNHSLRVWSFVAANFVASLPGIFVISIVSSTIVIALTGLQRFPMFLLNIFLTLVSAESFMCVISALVPNYVAGIALGAGFYGMFMVVEGFMVPINALPVYWLWLHYAAFHSYSYAALMHDHFSSIDTPSGYAILSDYGLVDVDIMRNMLILVTYTIALQVIFGILMRYRHCGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H1</accession>
    <name>A0A8K1C2H1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013131</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2H1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470296" description="subtilisin" evidence="8">
        <location>
            <begin position="20"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="189"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="58274" checksum="D69D31F05BA99B5B" modified="2022-08-03" version="1">MSAWRGLCRWLLLAAVCPAAPSTASPSAAGGQDAVWIVHLSPRLRADDLSPTSLGWSPQERAQRRQDVYRLCEERVKNAQEHASAFILGQEWGSAVAIERVWIQNALIVRIRSSETHRALDSTLFFTDSLRWLPGVTEVERDGDAGISLIIPSTEDIPSLHVTQHIADEPQKNIRLLHAPELWKKGVEGEGVTIASIDSGVRYTHDALYQTFRGRVSKAMASERRVTFDYSFWFPSGTDVNKETPDTADEVGHGTHTVGTAVGQLGIGVAPKATWIAARAFDLHGAVKKSDFLLATQWVLCPTKVDGSHKNCSLGADVITGSFGVDRSDVETYKQWTWITHILQVWRAAGSYAVFASGNTNGFKCGSVYYPANREESVAVGALIGGYTLWGASGKGPSIEDDEENGKMVIKPDFVAPGAAIRSALSTADSAYTRMTGTSMAAPHLTGLLALLLSAAHKSKSFLVDADLLDSLRSTSSHELSKPFLVPSKCGNTSYNQYPNNIYGSGLPDVCAAAKKAFGIECVSTSTDRVTTNELMSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C327</accession>
    <name>A0A8K1C327_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C327"/>
    <dbReference type="OrthoDB" id="79171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21182">
        <property type="entry name" value="Tudor_SMN_SPF30-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13681:SF26">
        <property type="entry name" value="SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13681">
        <property type="entry name" value="SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="4">
        <location>
            <begin position="95"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="4">
        <location>
            <begin position="158"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="361" mass="39647" checksum="2D12A3AF3596213F" modified="2022-08-03" version="1">MSDASLEELHKRLATFTEQLESIHTLLQTDPENAEFLNIAQDLVEVIRLTKEMIDLKLNTKSTGGNNAVVTSGRADSTQEDEEETTTSSKEPVLGFAPGSNCEALSQNTWFPAHIESITANNTYKVQYLGFGNQDELPASSLRAIEQEGAELLPPKDEITVGFKCRAKYYVDGQYYTAAVTALTTYGFQVLFDGYGNSEEVPYEYFRPLPASSDASTTASAPVAVSSTKTAAVPALPSREAVIAKPIKVPENLQILPTDSEAEKERKRKRLKHINKLNKVKEIENERNIKQHDWRSFQNKAMKKGVKGSGVLSKRGSMFASPDTVQGRVGVVGSGHGMTAYEDTRKKAKRSHLEGSAPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E7</accession>
    <name>A0A8K1C3E7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3E7"/>
    <dbReference type="OrthoDB" id="123275at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33206:SF1">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33206">
        <property type="entry name" value="PROTEIN CBG10425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="234" mass="25660" checksum="7C2B66B4592434FC" modified="2022-08-03" version="1">MNVSADRVDNKKGHIDGNIITSCVECNVARKDMAIYAFKRKKLMEFDADRLVWSIDEEEKDIYHKMKANIAGGPSIIFHRFAKRDKTYIRNASELNGGEDTVHLHPANYALVMKAKRAGKGVRLQLAEGEIIYDMETIQGGSFWSWIKDKAYPWLKKNWSIIKPVASAVADVAVPAVATAFGAPTAGVAARQGLKQLTGVGFAKKGGKLVKGSEAEKPSEPVILEASDSTKPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3F5</accession>
    <name>A0A8K1C3F5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010629</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3F5"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF9">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="572"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="651"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="717" mass="78309" checksum="70E761766E7C964B" modified="2022-08-03" version="1">MDTSMAATSVRPPARPSDLHALCMQSRQRALHSSLSRSQWLRVGCVMAIASATINLPLADAMPQSSVKLPAILECSSCDTPLATDIPFCGEYVRYSACRTGESWTSMDKAVEAEYTSVANSSTVNASSSEATECLTALKRVTCAKMFNVCEMGSPQSFCLSSCSAALKTNCSAVLDTQATLLQETQTKVCGSKQRLPMGVVDGGKCFDVEYEGPKRTAWIIGFTIAVVFSFLASVGINLQKKALKQNELTAHEQNKEPLPAYRLPLWVLGFVMILLGSILDFVAFGLAPQSLLAPLAALTLVWNMMLAPCFNKEKLSKKDIFATLVIFAGATVAVVFASHTSPSYNLSMLMELYTDPLTCAYFGVVVCCVGLHYSLIRFVEKLSLTSKRHRMIQVGQPLVWSKVRLIGYAGLAGTMGGQSVLFAKSTAELIKAAFHGEDSFAHVQTYLLIFALFSCLLCQVHYLNCGLVHYDALSVVPIYQAYWIISGVLGGAIYFQEIRTFSIEQACMFVLGIVMTIFGVGLLSQRKPVAQPSMKRKLTIDRGTSFSTSDSKLDKPSSFCGLAPVPEVVEPTAQSDDDTHSVDTMPTIQENESEMSTGEESDDDEENPDAVSDDASDDVNRHVIDNYLDMSATMCFTEILDGLGFQNGPQRMLMSRRPSTRNISHDGAGRRPPRRSVDDIEVGMPAASRENMPREKAPKRRSITFSAFQNKKDPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3M7</accession>
    <name>A0A8K1C3M7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3M7"/>
    <dbReference type="OrthoDB" id="10255570at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF17">
        <property type="entry name" value="DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="375"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="917" mass="102269" checksum="320D7BAB8D11A6E0" modified="2022-08-03" version="1">MLKPMGKKSKALASPHSLEEWHAQALQRHASGSGGGALLLTPHHAALRIQLRYRVYKDKVRALLKKTTDRARDDTTNGQSSESVSTTVAGSVKAAVRERGVKGSSMALAAAYKARGTGGVKESEGEIQPLVIKSGKPGYVNAAQEVRPPIQDASTGWNAPEWTPPSKSFVSQSTEDDENETEEEPDTTSLSVLGASADHVLSVVDGEAVLVRGRPKNFVNVMHSSWLLSSIEDRCAEAAASLGARGLTGPHKQLTVVDIRHTVLDLLFILRSGVSENFHGRAPSPIATHHKNLVQRLVRSQSEDGQALSLDEEALRRVRRIFDSLKSDMVMPAVRCLGWILTKTWRMLFSGMHVDVESLQRVREVLEASSPNVSVVFTPTHKTHLDYLIISYLCFAYGIPLPRIAAGNNLDLPLIGSFLRANGSFFIRRSFKNDDLYKQVLQQYVHELMSDGNPIEVFVEGGRSRHGRVCKPRLGFLSMFLDYVKQQAADEGKEVLLVPISLDYDKVFEVEEYANQLLGKPKEKESLKVFFQSVWDLLFLHCGHCYVRFGEPVSMTAETSLKESAETLAIRMQTSGTITSTSIVSALLMWSRAYTTRDMLVTRAQWLVDELESRGAVVAHLEDIDELVNHALSVLNVDVEAQGVIKSKLSFPTRALEMGFYRNHLLHVFLPDMAVMGAIDSLRLKHGDHEGSEVTLDRGTVLSTAESTWKFWRHICRHDTVDLAQHLEALVLRVPHVSVTLDKVTIDVSKWRVTRIVSFALSLHWSFMDSLWLAVLASWHLKTVETCAERDTVRLAQWIARELFTRGQLQHAEAFCSESIKQAFEFLREIEILNFVSCATTGARLYKLAETSEVKLAELLEHVNGMRKPKTFLYRSDQVPASLLASEVLELVHKAAKNAKETNGRGRNGVYATWMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C409</accession>
    <name>A0A8K1C409_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C409"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="303" mass="34117" checksum="B4D7F4BF63C21BA3" modified="2022-08-03" version="1">MTERIAVLFCHGGSFNKETWDPIVQRVLASSLLERVPVEVLRLDWTYHGSKHNFDEPGEVYYLDDDKDLPRVKHACNEWTVWAPEELHAFVQSIRAEDEALGRKTRLVGVGHSMGAASIMKVEMAYPGTFEGIVGFEPICNSEMGPKIGKILSTKMVTNTLARESEWDSWDDVLRYHNTSKAFHRWNEESKEAYLKGGIVKTPDGMFRLACLPSQEAALYCHSIMTLGVEDHARMGCKMVYAHGGSTMLFSAKLTKTIADALPDQVFLSPAIIGRTHMMVVEDPESCAERIIKAFELFPVFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4C7</accession>
    <name>A0A8K1C4C7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4C7"/>
    <dbReference type="OrthoDB" id="71637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="568" mass="64272" checksum="6A6AB12DB6EBAE6B" modified="2022-08-03" version="1">MAATMQRNEVDAFLASSMVGLGTPELWQRMSLELDGKTTLEKPHVSKKVLLKAIRMQTDAMRYLVDEFDRLRDKMQDMEREAKNAQKHVERVNAKLITLQGQFEEMTTQVHELEVKQEQQVEQLKRIDEVAAQVRENEKEIEEMQQQIVLCNANHASFVEKVEQDLTALRHDQEVTKQFALQLEDRMNAEEKELFLNSDHIIHNKLTLAMWMEQTDKESRRKDDAIREFTEKMNKQAKNVQEMMLETRRTLDDNTCAVEDVQRLLLLKADRAKVDEVIETKYEEICNQLDKALAAVIGEEDEFKRVSQELQQLVTHLGDSKADKKDLLEVKEQVLYDSRVRQQVENLRAFIDLKMNRDDVFSALKNKADKDEMVALLKGLSDSMNASIQQAQRTFTEAESAFLTGKNVLPAPQKRGGMLPSLDKERCLSCNSVIRDSPAPNGGALTNKSPHPMAPVYGGGFQVASVAPSPLGNVRSSNNNDSVPGFGARNGRNGNNTSSTGALLSESASEGYVLAQPSGKIHLLTCTFVDFSWVLTGTCTKPTQKCLLYKLKTVYPRKAVQLSRFHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4K4</accession>
    <name>A0A8K1C4K4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4K4"/>
    <dbReference type="OrthoDB" id="2408259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="424" mass="48983" checksum="479C80ECCD5FE2EF" modified="2022-08-03" version="1">MERQFTFAEAFIVATSGISWREATEIIPASESRVYLVMDNVEELYRSEFQTFWHLVSRVLGDRHSPIRLLLLGEYPPYARENDSFKPVQIPCHLGVRDINFTQNEIREYVTKWCNNPDVLMSDGRGAFNDFCRYLRMLCGGHIGMCELVVRGLNEWASEIGEKKSLTVDDAILKILNGTIMIYLRGERATRPINKLSPQDLVNLENIALGDVTEGMHGVAQAFVQRGILVPLAGRYEFVSPLYWRIFASLCLRGTPRASQSPENLSDLIIQAIQSIDYKRIRERSRSSGIVMEKSWQLEFYRAMLRVTPDAMVARYELGVLFGTRGWIDFSFHDDWHTWLLGIDVQHDGESLDELFSRFEDGGIYLRWPVTEYCVVDFRRSEDASVEEIARDVDRYVTLFVVRYDVRLSNVVLYNGRNQLSIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4M6</accession>
    <name>A0A8K1C4M6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4M6"/>
    <dbReference type="OrthoDB" id="106908at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="137" mass="15476" checksum="C9D8EC15A91B17AF" modified="2022-08-03" version="1">MSAASASAPVLRTMQATDESRPNARATVEQFDREFQQYTTKHGGKSARAVAMARAELSKYRALLWQDDKLTAAKAKQGRLTAAQRAAYEKKVADIEKALDQFHHNVANYNRTKAILSFMLLTAFALLAFFQPWKKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C517</accession>
    <name>A0A8K1C517_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Neutral ceramidase</fullName>
            <ecNumber evidence="5">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006586</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the neutral ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="5"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C517"/>
    <dbReference type="OrthoDB" id="191371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF1">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="7">
        <location>
            <begin position="143"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="8">
        <location>
            <begin position="628"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="801"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="596"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="824" mass="91152" checksum="0471F2F8D03E9498" modified="2022-08-03" version="1">MPMEMLGSSTGAAVSPPTGRKRRRSKKKRKQQTETVSNMSPSSPDSASSRQEDPEKAAGARTEHETSRQSTTSGNQNEDDVFQGGDRPAKRLRDAAGAMASDSTPVKATIPVRSRRASSASSTTSSVFHAPPPETPKHSELWIGAGMYDITGPAAEVGMFGYAKVGQLTSGIHMRLRARAFAFRHEPTGSACVYVCCDLGMISEWVTQTVISRLSVHPAIPKAAYSRENVMLSATHTHCAPGGMSHYVIYSMHPPLRGADRQNFECVVDGIVEAIVRAHNNLQPGFIRVAKGECLNASVNRSEDAYNANPEEERARYKHNIDKEMTLWRLDGVNGYPIGMINWFAVHPTSMGNWYTLITGDNKGYAAHVFEKEHGTHHLLDRPRAFVAAFAQSNEGDVSPNICGPRHHETEHKDFERMLIVAKAQLKTARDLYHKALYEPPLMGEIRFAHQYVEYGSIKLTERWHVHKECPRSTSSGCIGVSMIGGTTFDGRGVEGIPEGLTWGMYPKVTTMPELQQSQKEKPVLFPSERYGLSPSTLPLQLFLIAGALPIAAVPFEATTMAGRRIRSNLHEIFDELGVETYEPILSGLSNAYSGYLATREEYAVQRYEGASTHFGPNQLSATLQQFEMLAHALTKSKKIKFVTQKPPKISGVGVLDYNVPVVHDGLLPNTQYGGVITDVLKEYHPGSTVTVSFHAAHPKNNLRTQGTFLEVHRWREDQDRPEGGVWVMHADDGDANTFFHWRRRGTFASVVTIEWCIPAQTPPGKYRIKVNGDFKRFFTANVTSYSGVSSAFTVVPSVEEEVEANGHDVDKEDEDPEVQEAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C641</accession>
    <name>A0A8K1C641_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C641"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1046" mass="118856" checksum="497BEF16D73F13A1" modified="2022-08-03" version="1">MTDEAALAALLRPWWDVFPPNNALQVQCDPWKPGLRKKLYALRVDVPTPSTGVEATWRRQLNAIELLLLALQVNPRAFMRLARTNCSLSPAYGSWSEVDEDEMLPCRLMIVFEDTLMSPCYPMWHRDALRLLLSPELHAFDWRGFHETRQALLAMASTPRERRRCETMKIFVCTRFLFLKEEPVCETLMDLVTIQHKRSSNNQSISGEREYPFQAEAVELVYATDILDRDRIAFSYEMLDSVKRLVTTDGAVLRWMHLLEVRHTREDHQHREIMGDFIRAITATQAGVTRGSTYHLGTQVIETVTTDPGSFSCLCSGLMHSRGVEHVTLDGVFVRLAGGTDPILKWYWIIYSLFHASATHSITSLEIHDTNLLTEHARYVRGLIQASQPVTLIYDVIPEHHSNFEWRSTPQPGSLVVLADDAPLFFTWQTNAVNTSSLNASADAKPFRVIYAFGSAVSILVPGYGQCWVRRRDIVSMCPDPFQDQPEHQWKLKTHRVTHLNITLEDETQDMRDSVLGVFTLLELIGEPITSLTIDFPCTSSAYEVELSKLWSCCPNLTELSLNCTTLTSFDELIDAYESGACQVTSLDLCACCMLTESSVVSLAAALGDHSMAIAQTLRHLRIELEEDDLGVDQEVDEEGDFKVKLSEKDKVVPFLSALELNDRLSYFELCVSEDVKQEYHDSFYALDGRLIVYPLSSRAKCAFLSVVRRAQKESEEIQHDVWQGGMRKELYALNTGSSAVHGADTKCTEDVETMTIQVCVRLLFLTEEPVNAVIKRLIHLKQARPKKYRNPERKDVGRRRSEFPFHAESIYLVYDYTLFDAHRPAVTPTMVSTLKALLKTKGLSVRQCRFIEFMRDTLRDESEYRFIGGDLWKSLTGAPTGVGRGLNDRQGAQVIESVMTPVPHFSALCSALMYSRGVKHLTLEGVFVRSAYEDEHLIKWRWIIYALFHASATHSIRSLEIRDIEIVMEHLVHVREFLDAPQPLKMMYPKEREPPNSAALLSTPIVGSFVALAEHAPVYFRWNPLNSEKNLVASSANTQFRVVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6G0</accession>
    <name>A0A8K1C6G0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_003396</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6G0"/>
    <dbReference type="OrthoDB" id="442428at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="11">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="913"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="1110"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW57471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1216" mass="139547" checksum="1BB5D3FFB674DC08" modified="2022-08-03" version="1">MGGWLTPEDGVVSNYYEDQKLMEGPLIKLGDYAHFRYFLLYRNGRFCYYELPMPKEPSDGHGGPRRIQLTLSPEHLRGVMMLNVTLIGKELPQMEDEYASDAIQRGLAFNRKRLEMNLTGISLTGQLTSWKLRASNDATYTKWEKAFRLALRPIWMQNTSTCMICCNEFTLLFRPHHCRKCGTCMCEECSVFVPRLAMQGYYDVVRICRDCSPQNIQQSDLKVGSRVLVYGMYPGKIIKMDATEDSASSSAFVTVEWEKKKSDDSPAETRRVGLGYVEHYSETVLSANRIKNTIRRHLAQTLFRAQLNFSTWNQLETVQEQRTVQMVRILSRSSSINDLRSMVPTLGSYDAPQFIVDDEKEQELIQASMAHYRGVHITFPLRLETAMKLIDQFRNGILLHRVYVYQILDEAHKALRRWNPTPMNTISIQPGVSLIVVGDLHGQLEDLLTILDKNGVPSQKTWYLFNGDFVDRGSHGVEVMMLLLTFKLLYPEFVFLNRGNHEERMINENFGFEDEIYAKYSAESANFEGADTISCSQKYSCVKLFEMFEDVFTILPIFALINERVFATHGGLSSHENVTIEELKKIDHLREIPTQGTRREDELFTHLLWSDPRDIEGYRPSDRGAGIEFGPDITKRFCADNQLSLVIRSHECQEEGYEITHDGLLLTIFSASSYCGSQTNKGAFVQLQVIDNGSLQPHVVQYYAQPLQKLLDAGKNEWRKKAVRLERRTMMSLAELICEKKGALAGAFGQYDREGTGRVTKLQWRDALQSVLDIEVRFLSYFHDLAGIDADEHDRVDYEAFLSRYSVELNDGNVDWRRHLLRRVWLAFCEALKAKEGEDVDKMSMPEKLRAAFNLFQSSSVTGNQDSQVPKELQSIRGVATQKSHDNFVNNGFIAYDVFRTTIQGRLGLGDTLSEQQILELMQHMDQNHDGFVDFDEFRIFFAEFSRVDYLQQIFDVDDVKAVDLLQQFGTHLNSYEHFETLQEAFKAIDRSKKGTLQPEDLQIASQTIQMIPSLDEEHAEILHSAILRTYYGAAPAAQRKLDWTVFEDVFSPDSAHQRSLLMTSFSASGSNLLSMVGNDEDARPLSPRSRKKQTWIDALLQQVTTSLHEQRLYLKFVFRMLDKKRRGYVPRSKFISAMKCVNHEYGSPLKDDQLEQLADAFMVRTRRARAFTDSESEAQEMIAYPSFLKSLRVTPEKVVAGGKTIEVYPFDDFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C721</accession>
    <name>A0A8K1C721_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycoside hydrolase family 19 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014407</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C721"/>
    <dbReference type="OrthoDB" id="160168at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00325">
        <property type="entry name" value="chitinase_GH19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.20.10:FF:000001">
        <property type="entry name" value="Endochitinase (Chitinase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.20.10">
        <property type="entry name" value="Endochitinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016283">
        <property type="entry name" value="Glyco_hydro_19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595:SF79">
        <property type="entry name" value="CHITINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595">
        <property type="entry name" value="CHITINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001060">
        <property type="entry name" value="Endochitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0611">Plant defense</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035434155" description="Glycoside hydrolase family 19 catalytic domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 19 catalytic" evidence="7">
        <location>
            <begin position="118"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="181"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="274"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="308" mass="32731" checksum="3DCA6F8D163AD918" modified="2022-08-03" version="1">MKIPQLLSAIALSAFVAETVAADGYEYVGSTGDKTAMTQWCNWNCPSYCPTDICKATGGSSTTSTTTAPTTAPAVTTAPATTAPAATTAPTTAPSTGTGSGFSSYLDEAKFKQLFPDAIDLYTFSGLVDAAKKYPTFASTGNEVNDKRELAAFLAQTSHECDHYKAAEEYAKDTFPESQYCNAGQVPCAAGHRYHGRGPIQLSWNYNYKAAGDAIGVDLLNQPELVGTDKSITWQTALWYWMTPQGGKGIIHDVATKDDGFAQSTNIINGGLECGGPNQSNELQRIEYYKKICSALGVEPVSKVSCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C781</accession>
    <name>A0A8K1C781_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lysosomal Pro-X carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C781"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF120">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="60609" checksum="D56418871FB09757" modified="2022-08-03" version="1">MASESTPMLPTAATQAPASSRRRRQLLLGAGLVAIVTVLVISLAGSGSVSDGVDKIHSIVTGDDAPAFTPTVTFPADDNGRRDLLKYCEEKTITQYLNQFEVNGGGSFEQRYFVCGQQFFNAENGTIFFYNGNEADVLLYLNNTGLMWENAEEFNALLVFAEHRYFGKSVPFGDKVLDHLQYLSSAQALADFAVLINTLKDELQADVPVIGFGGSYGGMLGTWLRLKYPQVVDGVIAGSAPVLHFVNDPDHPVDSEAYMRIVTFDMSEEAGSSPNCIPNVRKASETITKLGKTEEGRKTIASALRLCDSAPLDTEDDIVNIIGAALGAYGTLAMGNYPYPTAYMTSGEVNLPAYPVRAACEHLAPDFGNDDAALLNALRESYGLFYNATGKETCYFAAADPSDSNQTLAEDIKGNFWGYIECSELYMPMGTDGVHDVFPAQPANATQDSANCEAAWGVPLRPNWAVTQYGGLKAIRASSNIVFSNGNYDPWSGTGVLEDVSDSVVYLPIEGGAHHLDLFFSHPMDPPSVTKARETEKKHIRKWIKEFYADKAKRTASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7C3</accession>
    <name>A0A8K1C7C3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7C3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437682" evidence="1">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="117" mass="12153" checksum="AFB5CB0E1AF5204B" modified="2022-08-03" version="1">MKFFAPLVLAVVAAFAVTADAASVRGLQNLPSIDNPIKVAQDILGEVNAAVPSAQRFDSHTLEVLARGIINAPGGVAAADGTTKIAIDKLQEAVAKRFPGVPIEKALQTLIDLIPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7Q1</accession>
    <name>A0A8K1C7Q1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7Q1"/>
    <dbReference type="OrthoDB" id="111500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48423" checksum="E1B13F59DE3CECC8" modified="2022-08-03" version="1">MLDVYERAVFTPSREAATQGSFLRSYMLSLDMSAGMVDALFRDKKLPGSGKMRKTRESYFISDISRIYSLLTQNDLAVIRRESSPMSKSLKELLDGVAELSRQELFESRVLSRDMLKLSDDITDIFKALCVALGRENELEGFLARGILEKSKQTRLLEEGVMFSMLPLLDRLELDGSIRDDKDDNVQLLTVDLNGDMVSIVCRQVANVIATHFEESEKEAPWIEDTYFVFPDTPNWVSLEFGDVKFLGEEEGEIRDNLFGILMGMLHTSDGPLTGLKLKFFKFSTTRDPGVLSIEYDIQPGVTPRPEHAGMDKLPMLLHQAAAGPGRDKRLVEFMVQMGALYNLPLHWRYPPAPGTLPRGVTRGMFCNQAPVHSAAELGMTDIVRILVAADHMRDMNTPTFHTKETLLHLAAKNGHQQLYEMLLWLGADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C942</accession>
    <name>A0A8K1C942_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C942"/>
    <dbReference type="OrthoDB" id="201048at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="36"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="281" mass="31263" checksum="96F3679B193C3E8B" modified="2022-08-03" version="1">MVSPERVLEYGSIAPEGNDKVLVIEPSAQWPQQGSIHFDNVVFSYKPGATPVLKGLSFDIKIKEKIGIVGRTGAGKSSLTMALFRVNELESGRIMIDGTDISTMPLQSLRSRLSIIPQAPVLFKGPLRSYMDPFDEYTDAEIWEAFEKVEMKNQISALEGQLSHELSENGENLSVGERQMLCMARAMLTKSRVVVMDEATASIDHATEKKLQHMINHDFKEATVLTIAHRLATVVASDRIMVLNDGKVVEFDTPHNLAQKEGGVFYELAMEGGYLEQFQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9F1</accession>
    <name>A0A8K1C9F1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9F1"/>
    <dbReference type="OrthoDB" id="30881at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="29624" checksum="85C5B0819271059B" modified="2022-08-03" version="1">MTSVGMRLAVAAALALLLARRGLKKQSLDVSGAVAAFLVGFGSMAAGYRFGVLLIGFYFSGSKLTNVRASVKSRLDANYKVGGQRSAPQVLACSLIATVIAVYYAFLFGESDTQAIDFKAAPVESALLTAYIGHYACCAADTWASELGVLSTHDPVLITSFKRVPPGTNGGVSLLGTAASTAGGAFIGLLYYLVSLLTGGAQLQVVPFGAVAGLIGSLLDSLLGATLQSTYFDPETRQICEETHSLSANSRRMHISGLALLTNEQVNAISVVLVTLGSVGLAHVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9K5</accession>
    <name>A0A8K1C9K5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000016">
        <property type="entry name" value="ATPase family AAA domain-containing protein 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="829"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="1129"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1269"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1560"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="293"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1296"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW58938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1660" mass="188249" checksum="59BA66A6E8E2ED7E" modified="2022-08-03" version="1">MSILEEIGSTASGADTPSPSSTVAPRGRLRHSTRITGRFKERMREAEDEEDDEKDDRDESPPAKRSSQRGRTASRPPVEEEEEDGGEEDEAAENASRYAFRERRQSHPPNRFDQKMYDEVFEPMREYREAQTARKKRARRRRRRSGSSRRPSKRRRQSVDEEEGEEEGDDDDEQQEEDEEDFATDTSDVEELSRRIAAQERAEAEAAKATADASRSTRQTRYSLRTKESDTSVNESFSPVRKQTDSSGSRRTGRSRRVEREEEVAVDTADENGTAEHDDEEDEDEDVEEEEENGKRYYLRERNLPERRPRSRQSEAYDRRERSARSERARRRADDRELPINDNEPRYSLRDRSKVQRNGETSPTKDPTQRAFADYSKRIANRASSQRRSRPYNALPSSSRRPERSNSRRKHRRRRLSGSSSSDSSDSDMFKYYDSDEGGMRTSGGNKHRGAPVDRKRADITPVEVDRSITWDSVGGLEKHIEALKEMVMLPLLYPEFYEKYNITPPSGVLFYGPPGTGKTLLARALANSCSVDDDGLATVISPDGTEVEARKPRHVTFYMRKGADCLSKWVGEAERQLRLLFEEAKRNQPSIIFFDEIDGLAPVRSAKQDQIHASIVSTLLALMDGMDSRGRVVVIGATNRLDSIDPALRRPGRFDRELGFKLPNVQERKKMLHIHTKKWNPPLSAAFTQEIAEKTVGYCGADVKALCAEAALCSLRRVYPQVYGSQDKLLIQLDKVVVSRGDFTKAMKKITPASNRTVSSFAAPLPRGVKTLLESSLTSVLKKIRHHFPLFPLDIQEIDGMLKSDGSANDMSDGDESHDHDIYAIMNRDDCDVCHGDEGELLCCDACPAALHPGCLPGDHERPRDDEGHDWFCPDCCISSRVEELAEAKRRRESQRRARQMYALPQHVGFPRVLITGASGMGQQYVGAGLLHAMEGFTHFSLDYPSLVADSNTHHAEEALIHRLNEAQKCLPCVIFLPQADLWWENVSESMRTALKMMLMNMQIKANLPVLFLAFTSSTVYNGLPRGLTDLFSYDKTSRRTSVLWEIRETSRPKRREQFAQAFSAFGAEPLPRRKRRRDEPLEVLPLAPVMKQKREPTLEELVKIKERDMHFLRELRIFLGQVLDYCATHKPYTPFLFPVDPEAVPDYYLIIKNPMDLNSMREKLNDGDYTCFEQFLDDIQLIVQNANLFNPKRSATRHIAHSAGTMKDNILSFAHRFRKHQGYDLFAKCREITKRLHTNPLFYSDVNIPAHEVPKAARAMQKALAAAPVRTSARLKGEKAPESVELPSRKHERRSLDSSVEKDDDMKMNSVDEDPDDEANQWFSVREESTTAAGIEVAAESESTDRDEPPGSAEDTQTHETFNVGDHVFVQSRMYPGMNKEGGAGKIVLSNDDDTYNVKYVLGGSEKNVHARYISHLTEDAVKESVKNQRPAESVAPSRTAEVEEVKSEEDLKLEFFDKLVWPMLVDEGWTRNEVMDEEAGVLVTFSPDQSNSQELKGVAAAMEYIKSDTTLAIKCFGKRFAEEPLTEAVFDESTTQTDELLSSAGRADAAGECANQENADGALTESSTTVAPAPTDATMKENDSEEEQPPLIYDEGRMIRALDALVEKTAGWTIEELRDELLLLNKLAYPFRYNHDRTKLMEQVEVHIEKIRPKASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAC8</accession>
    <name>A0A8K1CAC8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAC8"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF119">
        <property type="entry name" value="OS02G0119300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035442348" description="Peptidase M14 domain-containing protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="5">
        <location>
            <begin position="307"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="783" mass="87355" checksum="80E9BF0287614154" modified="2022-08-03" version="1">MALGTRFPVRFFAMAVATAFAAPSESVSASDLSINRRPYCSSEQMWYMDPSINEDAIDNWENRDWDELERFWYMPRTAKWERLEKCEGDSQATCYSRDHVKIDKTGLVLSATPEAGARVRIEKKVYSPWRSTSDMKTVLNTTLRLSMHVNFPPAESQPRARVKAAIYPLNTVFIVGLIRTGNSKHQLAIISPSHNVSVAVDVPCGSHITNRFHDLDLEWNTQWLRWYWDGRVVYERVHSVQLDTLVGSLALEFALSASTMKNDVFRIKRTCLSQPYEDNPTCRPLLDPDTNCRDHATVQPRLGANEGFLSLGQVNAYLHNVSVSTQFPSSFTRLETIGYSHENRSILALCVGACTTPSAPQVLFTAMHHAHNPTSMMNLIYTIDLLSLDFANGVLDVLTVLYSRQLWFIPLVNPDGYAINEQLRVWNWKSDEIGHRKNTRFGGCARPTGNGVNLNRNYDICSNQDERGGQSKPCEQNYQGTAPFSEPETRAIKEFVERKDSHFSTAVNYFSSGWFFNIPFSCEAKGKITDEIDLAIYNSWAREMASNIGINYGHHWQRDNSFTVNGEISDWMWGAHGIFAISAQIGQNFFGERLWAPVEDIPRFSSELYNSNLVAARLAGPIHGIKIVRIDRVPDSDKMKVGAELVNNGLSTMGTVELIASITLDGAEGSVSSASVSAEELGTLRNGTHSVNRTLTMPIGNVVHIFVRDELACKYTRVAVGASPSNSSALIFQQFQALDLPPCGVCATLGRNGSTLVSQPRCEFVQDLVSADALALEITTLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAK6</accession>
    <name>A0A8K1CAK6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAK6"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="94"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="505"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="687"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="747" mass="82476" checksum="5D51F6E082BAC203" modified="2022-08-03" version="1">MASLSPSSASSSLDEELRRRRHETKHLRRSLKALKRDVASSFRICKRDFGVLGNELIGALSQKQEKERLLREALEYERVARRLAQTKLVDMQGSIRVMCRVRPLLETEKKDSRVVTVASMQDIQVQSGSSSSSSMMSSENSGVKSFSVDRIFHDEATQQQVFKEVQPLVSAAVDGQHACVFAYGQTGSGKTHTMQGIEDDPGIAYRAAGTIFEHLEAQSHLFVCTVRVQMVEIYNEELYDLLGSDQNSSSPLSAGNSVVAPFQTVQASALGPGFVSRRPLGEIRHGENGVYLRNVDAVTVVNPTEVLVAIEHGESNRAVHSMSIDEHCNRSHSVVIIEIQRVSRADGQVSIGRFVLVDLAGSERMIKSQTSGPRLREAQHINKSLAAISDVLTALLSKEKHVPYRNSKLTHLLQDSLGATDSQMLMIVHVSPSSRDVNETINTLKFAARASHVQNASTRRTERLEMNRLQGIIASQAAQLQALQEKMGGELELRRKYEKRLEEYRQEDHRRRAKENGQSTSPVPAPTTAVTTADVPTKTRIPGTPRRRLSASSTSKTTTPSRMHSGTGQENISENILRSQPTANLDGSGFLLPVPEKKSRGSITPGRRRRSSLTHGDRKPMFSPTRSAPNSGTKRKPTTGTPPRVRSILKKQRVDTDQTVVITKQVSFDLPSKQERVQTIASSGPTKPVPPLPPRQPKTLLRTPMNASRVPARVYRSATPTGLASPPGRVRSVGTPMRLKPKWNGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAS3</accession>
    <name>A0A8K1CAS3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAS3"/>
    <dbReference type="OrthoDB" id="155525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="451" mass="50332" checksum="9B5F9D4D04CFB997" modified="2022-08-03" version="1">MMKHASVSVTDGDPNAVFQEALALLDEYYNIEGFDLVAEPWYGKLDPLPLPVTPDTSVAFTPQEVPVSTVVPADDHHSPPHSGAHPRRNRQREELMKLRDEASTLESQLEGIKKRRQMHAAAVEALTPEEREMMAMWEKIASRQQDERQRVEVENTKLKDLLASQARVAQELRRLLEKQLKAQTTIPSLSCGGHGVPKLTCALHELPDLATFEDLIGGLEACYLSTDATFEASGLNAVTAPFRTSQLKLDDQVGVRVELMGKRVVPFCMNDMADGIWNNSRNGAMHSNYYFYTQADPSDDLIVRHVGLRVPHADVMVDLQGKHATRRFVEPNRVVIAWQASLEPQVYSGVPATDIRFRERGWVAVSRNGTSGGAEVKMFRVISPVVPPGMEPSADWRIYALIDFVSNVINSQGTIIQQKVENYLLENAAKRQMKSSTSPMHQASSIHQLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB86</accession>
    <name>A0A8K1CB86_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAR2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB86"/>
    <dbReference type="OrthoDB" id="201752at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.20:FF:000001">
        <property type="entry name" value="protein AAR2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038516">
        <property type="entry name" value="AAR2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="AAR2 C-terminal" evidence="2">
        <location>
            <begin position="205"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="44017" checksum="13110F1C0D5E9E01" modified="2022-08-03" version="1">MTSTGASTADIFKQALGNGTKQPPASTAPASGGHVGGFLVCLDVPEATEFGIDYEVFRTGPKFQGVKFVPLGVHFVVFRSREQEHGIRQGFFVNIERHGQVVVREWSAEKEELGPPRPGLNVEHLERAVLSFQLDSGLGPYPKQHAKVWQRLSKYISTSVLQRCGVDLGSLILPGDVEDAQTAAEDGGVIPFFPDLPRTIRFTRLMRRNTAEMTVQERTAYHFDKSAMVLELLSSVYQQDWKELLGELQLAFIAFLQLSSLTAMEQWKQMLLMLCSCEQALTTHVELFRAFLKLLRTQLEQIPVDFFQDELTGDNFLRPCMASLLELLRDAECPPELGSMGEQLTGLLQSRFHLDLGTELLDDDEFAPVVVAPDELDADAANMQVAMSFLRPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCF9</accession>
    <name>A0A8K1CCF9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nitronate monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nitronate monooxygenase family. NMO class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCF9"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000154">
        <property type="entry name" value="Probable nitronate monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747:SF3">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="38946" checksum="D34E0DC987FDE5F1" modified="2022-08-03" version="1">MKWLHRPSVAALAHKLRVTYPIIQAPMVGVSTPRLAAAVSNAGGLGSVGLGTSDVASAREQIRATRALTPQPFNANFFCHAPTTRDTAKEQAWLKHMAPLFAEYGVDAPERLSCGYASFVEMSDAMTEMLLEEKPPVVSFHFGLPPKECVAALKEAGIVTLACVTSPCEARLAQEVGVDALVAQGYEAGGHRGVFDPSHDLQLGTLGLVQLLAKESTLPIIAAGGIMSGKSIAAAIYLGASGVQLGTAFILCPESSADQAYREALQSDQAFHTWVSPAVSGRPARGMANRVFTDIGVSESILRDMPSYPLPYDATKALDRAARAAGSTHFAVQWAGQAAPLARPMPASELVQTLAEETEQVTQLQSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM7</accession>
    <name>A0A8K1CCM7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCM7"/>
    <dbReference type="OrthoDB" id="3229771at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF57">
        <property type="entry name" value="HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="611"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="801"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="742"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="811"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="850" mass="94269" checksum="6515340D62B369F2" modified="2022-08-03" version="1">MEFTSNKNDIAFDRFAPSLVDDSEPESFSVPSLATTTELVLDHSIAPRPVSPVRLFAALRARRITKLKTGLRKQQAPGSEPTNPEAATMPVEKELVVDATVTPEIHAPEIEEVEAPVTYRSETPQAPKEELMLNQAPITRAIRGRQSVIEAFMAQPILRLNFHKEDVMRAAVAPTDIMAETSKIIIASERAESPKHRFSSHSEWLQSMGLDNVTSMASRCFHARQRRLKVATPSREAIAVGVSIPPELQQQAERARKKRKEQHSLSKLRRKRQGAVKIEDTSRSEKEMLRDEQRSADPEEPMRKLKGTELPRLIKRGQTPQGQPVRENRHQFPVGRRSLAMHPHEETALTLALSECDTSHAATAVTTSTTAVSTQSHHQHVHNVDDPSQHPLLPLALPPSPPLNALAHAQAHLSLHGHSHVVHNGSHYSARLALLSDAGGNNGHNADNAALSAMAASYFPSDAEAAALAGVNMSVSSFAEEMKLAEAATSLSSSSTLASTTSTMAGDLSMASRKNKRKGGANVSIDLQTKIRLIELAEEYQYDPKSTGRGKQGEAGPATAAANANSGSRDHMSGIRLAAQFGLNKSTVSRILKRKEEFKKAYYKDNISGCSKHINKKSKFEKLNRLVENWFDVTREKKIAVSDTLIRDVGKRFAEELGIDDFRGSNGWVRSLRNRKEHQARNMSMEAMERERLKKDAEAIDRVRQMFPAGIKDMASFFKDMTIYLEKDGGGLGASTAPGAPNGSTSSNGTTSSSSSYVDLESETLMQDDDRDAEEFLKKKMIESLRSWSQELMELELAKMKKRLKPRQTPQQQQQQRQQAQAQAQQLQQQMQMQQQLQLQQQQQEQMAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD62</accession>
    <name>A0A8K1CD62_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD62"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="643" mass="66618" checksum="33D58B892C990C08" modified="2022-08-03" version="1">MSVMDDNVVSGNVMRRSLRASNGEEVGSNARLNATGSLGASTKPPGPLSVITPAPLASSSLSTGSSHTSLDLSFEEIGHNGSHVNAPVVAPNLGSITSDDIQKSTSMSSDVVNIGFTLRIPVSTLILASGGIVILLLLLVVAVCLCRINHRYKTLKTPVNNDSIYVLEHNQPPPQTQPSSLSLGLGHLWSGLRWSEPSQTSRDSKVVKIGRVRSEVPSTLISRYKYVLVMTRRRRPSVLALVAFVAAAAMVSVHGEGSQPMDVDVVAKLSLPSLDGSTANEPVDPEPTTAAEPEPTGAPSTTPEPTGAEPTSPEPTGAEPSKPSGGDDANASTAGSDDDVEVPTLEPVSPDSGSGSIAAEVTSPEPSTTPPTPSPTPTPTVTPSSSPSPTPTTAKPTPVPKASASLESMTDPPTTAPGSTASPDIGNGDLQPINGGGSSNTVHSLNSKSGSDSSLTWTISGMLVVGSVVAVVVGALFLARRKRRRLSEKADEDAAAMSRAAASRQHQGSSGGAPHVYAPATHQGSSAASATPYAHALPPRPASPQNAPPPVRESSFNELNDSGISSLMTGNNYDESNRSNSYADYDESNRSNSYGDYHQDSLDSYGSNFSIDINTNEDPYRPNSSLYEDFDDRSSTASSQANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE32</accession>
    <name>A0A8K1CE32_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE32"/>
    <dbReference type="OrthoDB" id="69983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="468" mass="53484" checksum="C334ADCB0B04FFA8" modified="2022-08-03" version="1">MAWPSEDDAAALLDAALYITGENDGAAFLMEDTAFTRDLAYTFASDRDVFSLLHVEGLEEPEETAIETNAQGTSVEENHGAVEDIGGTQDEDVIKKEVIEPPAQTASTKKRRTNRKREELIFLRSTVDELEGRLLKLKERQLRYEGTEDGDDSERNERKQSQMMTTVWENIANRQFEQRRQAEAENTRLRVMLEEQIRVAKTLERVMRKRSRSIDLLPPQESDKTKCVRSWNVLDDDSVFDTLINNLVVMYAEVDLILADRRLRSPPPFRDISLRNDVTLGTAVETCDCCILPFDFERTAAAVWRQYHKKSSPETGHDIHLQRAERAENTVTSEFEGNMRTLQSEYRGKIAVRRFVEASRVVIVWEVLVELLRIAGSPLDGVIMRHKKWEIIQPAPYQYTTNSPATLVRAYQLATPEILPIHEHADPSVTRSEHEKKAGMLTSFVLRSMELQLDTNHVAVENILLEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF03</accession>
    <name>A0A8K1CF03_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_010882</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF03"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051420">
        <property type="entry name" value="Ser_Thr_Kinases_DiverseReg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48005">
        <property type="entry name" value="LEUCINE RICH REPEAT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48005:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DDB_G0278509-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035424140" description="non-specific serine/threonine protein kinase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="731"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="798"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="825"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW61819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1095" mass="121552" checksum="9AA0006AB2FC6810" modified="2022-08-03" version="1">MTQSPGRPSAMRASLLVLITIGLVSAVEAASVRVHLRAHGLHKSETVEDDMVTVLPNITCPAATEPLASLDHGLIMSNCPSQCTDGSICVFYPSNLTEHCVTTPDRTCFQGDSCAYECIPNANLLFGWYITVYNRPEAVEEVIQYNTLFPDERGITLNASIVPTLDANFTLQSNAVFFYLSGNEAANNYDRNFMNKFAIPDYNSLPRGDIVPFQIPATLYKALESIQEVSIENLPLPAIDAAHPPVFDEMVHLFLRNTQLRQFPFPASSLKNLTLLDVSVNMITSIELGTLPEQLTKLNVSTNAITNIAIGSLPRGLQVLDVADNRIGAIANGTLPSTIMYLYLETNGLTQIPSDVASMVNLTEFYMTRNPIGDVPEGSIPVDLMDTLGLESCGLRGIPRIIQDMEVLTNLFLTNNDLSTDPDFTILPPSLTVLDVANTQLREVPKSLANLTSLVYLFLGNNPSAMHDLTTIPLTVDYLDLTNNSLDDVPPGVENLAEESLLDLSLNPLGKISPGSLPSTLYTLFIKEAVFTELPAGVLPASLVELFVEDSLLESAPADLLDTQLLANLTIARCHLSSFENVSDMPWLQNVNLQGNKLTSFRSRLPILVTLDLRNNSLETFELAQAPLLTSLQLGENSLTEVPVSIFDLKALTVLNLTHNPIHNFTPSVEQYAFLQGLDVLMMDQDMFNTSCDNLVSFREFAMCPPWQNVTNIEHESPEDSAQSKRGASPWTLVLNIGLLVVFVVVSVGVYHRRRIYKRRMREMDMKSAISDELNSKRGLSIWEDDVLLQHRLDNDLVIRSRMIGSGMYGEVWLATYQGKMVALKKLRHIEDRSLIQQFMDEIKLVASLDHPRLVQFVGVVWTKETDVSMLTEFMPRGDLRGYLDEHPRPKRNEPSSADITTTLWSRWKLQVALEIVEALVYLHSLEPILIHRDLKSRNVLLDNELHAKLSDFGVSRFKIDNELMTACVGTARWIAPEVLSSREYDESADIYSLGILLSELDTHEMPFHDAVNDEGEPLSDSAIAGQVLSGTLTVGFSSSCPVAIRLLGERCTSLTPSLRPTSLQVAYELRMLLRLHNESMLNEEVKVEDSHVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFE7</accession>
    <name>A0A8K1CFE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWP-RK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative transcription factor.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFE7"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044607">
        <property type="entry name" value="RKD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373">
        <property type="entry name" value="PROTEIN RKD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46373:SF2">
        <property type="entry name" value="RWP-RK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="8">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW62044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="37455" checksum="385D7A0A7AF289AF" modified="2022-08-03" version="1">MPPLNFSHLNTAIDDRHDFVHSPTSNSISMSAHLPQSKKAMLSMSPACNFEAFSLHFHLPLKTAAEKFGVRATAFKKRCRAIGIRHWPYRKVRSLKRSLQELNRCKEQGVLNDKQQYQFAAFKKQLDKLMSPETYGIDPSGRIPQHHFEDDGNDDEDDSGDDDSYASQSPRYGATFTECSISPVESDKTFGDFSAPSHLRSFRRQQATFASHPIKSMGAFSSELPGMSHRLAAHPYKYMYGGYDNYPSMNSNLRSLRSSSSSSSLHSHEDQYGDHPSSGSGLDNAQHEFMPSEMKYATEEDFSAPNSHIDYSSERFFDDVFLQISPDYGCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFJ3</accession>
    <name>A0A8K1CFJ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 8">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_009597</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Myristoylates adenylate kinase AK2. During the asexual blood stage, may myristoylate proteins such as ARO, CDPK1 and GAP45. Probably by mediating protein myristoylation, plays a role in the assembly of the inner membrane complex during the early stages of schizogony and in the formation of rhoptries in the late stages and thus merozoite egress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer composed of NMT and AK2; AK2 myristoylation stabilizes the complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 8"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFJ3"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.170:FF:000001">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000042">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015892">
        <property type="entry name" value="N-myristl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00975">
        <property type="entry name" value="NMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="10">
        <location>
            <begin position="74"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="11">
        <location>
            <begin position="247"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="436" mass="49711" checksum="CF668C1E8AE598F9" modified="2022-08-03" version="1">MSANEHKTPAASADADKLELNTVEEQEEFLRVLKQLNLVQPAAAMEAQRKQSDYRFWKTQPVPAIDEFPKDHGPIDAPKTVADVRQEPYAMPAGFEWAVVDFTDDAQAKEVYDLLTQNYVEDDTALLRFDYSVDFLKWALTPPDFRKDWHIGVRNQKTGKLMAFISGIPVKVRVYDEVMEMAEINFLCVHKKLRSKRLAPVLIKEITRRVNLTNVWQAVYTAGAVLPMPVSQCRYYHRSLNPKKLIEVGFSPLPPRMTISGVIKTLRLPAAPTIPGFRQMEAKDVPAVAVLLKKFLDNYKLVPHYSEADITHWMLPQAGVMSSFVVENPETHEVTDFASFYHLPSSVLGHAKYNDLRAAYSFYNVATTVTLTELMHDVLVMAKKEDHDVFNALTLMENEEVFQPLKFAKGTGDLHYYLYNWRCPRMPAKDVGIVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFQ5</accession>
    <name>A0A8K1CFQ5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maltase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_005267</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFQ5"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000044">
        <property type="entry name" value="Alpha-glucosidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035458408" description="Maltase" evidence="8">
        <location>
            <begin position="26"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="10">
        <location>
            <begin position="180"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="9">
        <location>
            <begin position="386"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="11">
        <location>
            <begin position="770"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW62649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="996" mass="109914" checksum="440ACC45A2661617" modified="2022-08-03" version="1">MTLSGLGNIRLGLQLVALGCVLTSAQQLVQHDDGSGVVRILFQHSASDPNIHYSADGKDWTGTTGVPMTRSLLEGEYSAANGWYQHEVPASQVKFVFNSEGKWHRSLWGEAYEVTSPGTYVVDSKEVASTVATTDAGYVNTTGYKVTKVQKGNGRFALELALNDGNVDATYGASIKELTVDVSQSGENAVRVKIADKNAKRWEVPRDLYTKGDLGKAGTAQWGGSFTGSGSNLDFSYTEKPFTFKVTRKSDGYVLFDTSKLSLVLKDQYLQISTAVKSDLSIFGLGESTRDSLKINPGDKHTLWARDQFSNERINNVYGSHPFYLGLNDKGKAHGVLLLNSNGMDVTLEKDQLVYQTIGGILDFYFVAGPTPVDVVAQYTSLIGRPKLQPYWAYGFHQCRWGYESVKALRDVVDNYASAKIPLDVIWADIDFMNKFYDFTTNPVNFSLPDLQKFVGDVHTRGQKIVPIVDPGIPDDTTDYAYSRGLEYDVFIKDTKGTPYLGQVWPGPTVFPDFFHPNATTYWSEQLTKFHKDFGYDGIWLDMNELANFCPGNSCARKPNTTCPLTGSVANIVTCCLECVDDMNKWDHPPFDINNVQVKDPLFKKGISTSALQYGSIRQYDAHNLYGFTEGIATTNAQENLLQKLAFTLSRSTFPGSGAYVAHWTGDNGATWDDLRWSIPTILNFGLFGIPMVGSDICGYVGDTTEELCARWTALGSFYPFSRNHNNFGQISQETYRWESVAAVGRKFIGLRYRLLPYLYTLGYEAHVSGTPIARALFWEFPQDVNARTAPALDRQFLLGDAILVTPVLTQGATSVTGYLPAGTWYDIFNYTRVVSKGESKTWDVKLEDMPVHVRGGSILALHQPSLTSTAARESPFDLLVALSADNKAAGQLYLDSGDDLNSADHSTIIAFRVDSLPLLGTTLTSHVTKAAYKDASSKKFAKITILGVAKQPTIVLANILTAVKTSTYDAAKQTLELDLTSLNLKITELTTLFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG16</accession>
    <name>A0A8K1CG16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_005462</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG16"/>
    <dbReference type="OrthoDB" id="1907495at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="13">
        <location>
            <begin position="46"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW62844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="15738" checksum="8FFDC46DAAB82C74" modified="2022-08-03" version="1">MATSRVLRARRATSTATKKATSQAGKKTVAKATQHIEWRGHRMTTFEKSVYELISTIPAGKVSTYGDVAKALSSGPRPVGQALRKNPLAPEVPCHRVVAGTLSIGGFKGQFGEASPCIAEKRELLGKEGVTFTKDLKIDQSCLHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG45</accession>
    <name>A0A8K1CG45_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">cGMP-dependent protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005507</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG45"/>
    <dbReference type="OrthoDB" id="63830at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001861">
        <property type="entry name" value="Hormonally up-regulated neu tumor-associated kinase-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0140">cGMP</keyword>
    <keyword evidence="8" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="103"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="445"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="503"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="683"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW62889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="88925" checksum="332DDB4E28051F61" modified="2022-08-03" version="1">MSKRAVTSRVHHVLTTARNASSSRRPRCGDRFGQLRNVQTIQRGYSQNQDVNGGQWLALAAGVSALTVAAMAGRNDTSETYAQSSMVTMHPIGSSMAIDEVYEITDEIIGEGGYCVVRRGIDRHTGEAVAVKILSKSETPAREFWTEVDVLRTAGHHPNIMQLRGVFENEENWYIVQELASEGELFDHLIENGAYSEQQASAAIRELCDALHYLHRKGIVHGDIKPENILLHNGRMCLVDFGVSFRLGEQFFADAQLTGTVAYAAPETLLHSVPHVQGGFESEAEYSLGPSADMFALGIVLYILLCGSHPFDPYNNLTDEEIRHRIIKGKFSRHTRAWQSISPPARDLIEKLLQPDTEKRLTSAEAMMHPWLAKNAELSQEPIRNSAELLERFQRGRRRLRASILGVLLLDALDDDEQDEHIKKLSAIAKEITWGVSSSVEALSEKAGVLMSTLDVFDREKKGFITKTDLARVSEKLGRPLTETELNEMLIGATGDPEQKASSIKAIGYDDVKLAISTLRSASFNPGDVIIREGQTGNHVYLLLDGEVDVSCKNPITPSSPKSTKNPAREGFGGLLNRTRASTAKEQKKEQDVSLQRLQKGSFFGAIELLRPEGELHPRIATYTCAPDSSCKVLQLVADDFLNVSGLYSSLNQKVKANARIHTQEQLIKCVEAMKGSVKKHTYQPGEFVYHEGESCDSFFIIMEGEVQVLQQREQVVVEELRTGDYFPLGVSGQTSNCMINTRHYSVRCTQPTRVIEIGGETFRSFLHSNQFMASYFRQEIIGREQMRDKTHTARLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGF2</accession>
    <name>A0A8K1CGF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGF2"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000205">
        <property type="entry name" value="2'-5'-oligoadenylate synthase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000001">
        <property type="entry name" value="Ubiquilin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="495"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="56086" checksum="F69DE43AA8FFFC80" modified="2022-08-03" version="1">MVQLFVKTTAGKKFSVEIELERTVAECKTALVAETEVPEAQQRLIFKGKVLKDDLTLASYGIAAEDTLYFVRGSANPRPTTATPAATTPASTPAPATPAPAAAAPTGAAPNAANPFGFPMFPPMGGDANGAGANPFGNMFGGAGAMGGGMPNINAMQQQMMQNPDMMRQMMESPLMQSVMNNPEIMRSIIQSNPAMQQLMEQNPQLNHIMNDPELLRQSMEAMRNPAAMREMMRSQDTALRNIESHPEGFNALRRMYHDVQEPLLDAASSGSRSAGPAFTMPGVAGGAAAPAQGQTNATSSTSAAPANPWATGATSAAGATNNASANPWAGGGLGGFGGAGGLGGLGGFGAGAPNPELMAQMMQSPLMQPMLDQIANNPQLFISQMEQMNPQMAAVLNANPQMRQMMMNPDFLRSMMNPQNIQAMMQMQNAMNQLRGTGLIPPGLEGMNLGGAPGMNLGGAPAGAQATPPVDFSALFGGGFGAPAPAPAPAPAGNPDEIYASQLTQLNDMGFSNRDQNVRALQATGGNVHAAVDRILSGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH16</accession>
    <name>A0A8K1CH16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH16"/>
    <dbReference type="OrthoDB" id="2155027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18874" checksum="96BCEE8F23981AF9" modified="2022-08-03" version="1">MNAFHVRSATSSDAEMLSHIAARTFSDTFGHLYPQQDLETYLAKAYAVDKMQEQIDDSDMYTVFIFSNKEAETPCGFSMLWDGSIRPGDDDRDTRNHLEFKRFYIMKEYHGTGAAGVLMKHVMQVIRQKQRQVVWLIVWENNLRAHNFYKKYGFQETGEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH96</accession>
    <name>A0A8K1CH96_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH96"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="20"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="7">
        <location>
            <begin position="187"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="39323" checksum="F6B9E85D68C091EA" modified="2022-08-03" version="1">MLKIFQPLDFKNAKPRHMQQTYVVQPGDTLAGIALRHGMKEAQIRAINNLWEGNVFAGQEIVVHRKQRSKSLPQLPSAGLTGKKAGFESVEEQRPPEEAEKEPVVEDDWVLTDSPPRSNENGKKLSVIFEHHPHKDAQQTQAGQGKSNGVGVRRIKVRSFSARFQTHQEEEDNIFGLPKLLGGTWGEVLANPRHADLVPKLEACLPMRYHGYDWRVMYSSAKHGSSLHTLLRLSQGKGASIIIVETCDGDVFGGFNTSSWTTSTSYYGTGECFVFTTAPKFEVFTWKRTNSMFMLSDSRSIAMGGGGGFAWILNADLSRGSTSPSDTFMNRRLTPDADFEISTVEVWGFETKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHU6</accession>
    <name>A0A8K1CHU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHU6"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20208">
        <property type="entry name" value="Bbox1_DUF2009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018553">
        <property type="entry name" value="E2_Ub-conjug_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057668">
        <property type="entry name" value="E2_Ub-conjug_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560">
        <property type="entry name" value="UPF0652 PROTEIN C16A11.03C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560:SF0">
        <property type="entry name" value="UPF0652 PROTEIN C22H10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09418">
        <property type="entry name" value="DUF2009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="783" mass="88880" checksum="36A858840B012682" modified="2022-08-03" version="1">MDVATPMCVECEDTDAAVRCEDCQDLYCALCFEAQHRSGTRRQHATTELFASAVAQQLAQPPPAPVQATTVAASAVQPAQESTTVVEGADEPMEAVEDKETNGKVDTADEETDEDDEVDSDADSDDEPTMVSDDAPLLRDAMYIPLRLTEDERAQFNLLDASLNVSEYTDKVDVLSYRSPVKRVIQELKEVLSTVSGMMVATDFRKGKRLVLNNKFEDNDTFFREVFEIGRRYKIMNPERMRNNYGKMIYMLQDASMREIKNYLGFSCVGPIQTVKSFLKKRHALDLLKDRRCVTATAVFSSTSLEDDEAKPEDFLQEKQRAIDELVRDYASSSLSANDIRLVLASIDDSQSYLVSNRTPIIRMIKYLNKFFQPDRIEPNFSLEIRAGRNGARLSHSHASQYEYVLQSLLLWRNITTAMLRLWWAIEEDLLEGSAYRLRDTGQGLNRVQHAPKTSNLVHRILHQTQKLRPRWVGSSVVHLGDHNVPNALMFIDKYTQVSRILSPIVNTLDEIANLAEHPDTKAYIMDFGGREELQKQILCDFFKHGFDGSGADNFFDAGSCIDGRLTSAWNWCSKIEKKPFFHVFLMAGFVGFDGQFESCQSIMSNTESVLHVVLIPGSTQPRRARNDSKRHKSPKLKPLQPRQPNNHTTNEDAESTMKHIETEAARLKRLMEAALSAKQVKKAEEIMDQLLLVLEHYHGILSMQQPQLRTQIVTYLEECDIRLNGMIAEASKCRRQCRFQGNALMTQVMERLADAIDPAKQEQVTMLLDQAEDAYRQAGDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI76</accession>
    <name>A0A8K1CI76_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI76"/>
    <dbReference type="OrthoDB" id="59690at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043007">
        <property type="term" value="P:maintenance of rDNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000042">
        <property type="term" value="P:negative regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033045">
        <property type="term" value="P:regulation of sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032245">
        <property type="entry name" value="RMI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33962:SF1">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33962">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16100">
        <property type="entry name" value="RMI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15202" checksum="0C5BF9F5E14615E6" modified="2022-08-03" version="1">MASASTVKAFIAQVHAAASASQRLTPTIHGIDCSRFWLQGVVVSLTPDENSCVIDDGTGVVTIDMKTFRKSIPAGMVPRVTIGDLIMVIGPLQRRTGATQTDPDSKHAVLAHQVMPLADQPEQEAIWFLEVTEFWNMLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIG2</accession>
    <name>A0A8K1CIG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012813</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIG2"/>
    <dbReference type="OrthoDB" id="111030at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="9">
        <location>
            <begin position="6"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="755" mass="84012" checksum="AB2C40DA5B39749B" modified="2022-08-03" version="1">MTRAGRRRSVVWTCFVENAESGKRRVLCRFCQHDIVANPIRMVRHIVKYCPNADEEHKKICRDYQTLTIPARRRTGGGENGTAAASAEVSDSSMTDLTTSNGVVSTSSAVAALTFGVSHGVDDTAGLRYGSRIELHQPTPAHQTQMEVDDPTATRAQDELVLGLLTSESSLALLENAHFRSAIELLRPHFTVPSVQDVSSSIVPRLRSGLKAETDAMLRTAAVVTAQATTWTERSTVELHVTDQDHRHTLWKIMPSDRLTEVIGDFIRQVAEAVDVATRKPTPTVHLCIDAFGPLSKTLVHELLRQADPNHGILGRCMIQTTLLLLHTVLDSIPSAARVIENCASLMELGINHPDVLELLQLQSEASSAQARQVSLDSIWSAIQVVDQVARCRSAFVKLGTDTPDSVVAELVRSERFWQEVKFVCDIMRPFGYVAALSEIGQATASLLMTCHLLVHATVGQSSIPTVAEKEEFERRFVIFVQEYCDEHALACLVLDPRTRGIGLSAVGKRKARGFIVEILNRMYGSTKQSQLVEHLVKYLNHERPFDDETSWQMMAPLPRLFWMEFMSEAPALAAIALAVLAFRPFVHPLEATWKRAISRLTRDQPVPSARDEYQDLRLHSELANKQTDEHRKLVLDVCAPICHAPMFNESVWNDEHTMTDDSITTTLPSEAFQELLSHLRSLASPSLASPPSEALQLFDSTWIATSSFEDLHHMKTCLHRALFGEDVRSESHYEASVPPVADDPLPHLVETHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIQ7</accession>
    <name>A0A8K1CIQ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIQ7"/>
    <dbReference type="OrthoDB" id="111457at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="787" mass="90160" checksum="D60410A1C2AA12C9" modified="2022-08-03" version="1">MLTPVDMKDNVLPKNSEVHIKFHQQNPRRGDFLYGTQATRRRMVVESVTGGGSGKDHFALGPGQYDLINNRPQTTGAVKFSPSDRFHENYSTDRPGPGQYLTNDELVSPRPVAAVFSQKPRQTNMASVTSPTASVVSSYYYVPKSSFRDGSYDYPDWSRSPRFKTRHRIGLASKKNNKQQSTDFVAKNMQELQKLAAQYRKRHGGGGRNQDDHDLNELAPPPVSFKRRSSILSTASAHRSSLSTPRHPPSFFHGHDKGQGDLVLQSWLTFAWISAVQARMTRIHQLTSLMRQILRSQNHKTKQVIFVEWKKLDATRHRHYAADLINKNTLRWRIWLRIHKKRWHVSILRQFLRGLSFDVRFSIAMKRIKRKIQLIQRWWRHVQLMVRAREEALYHKWITVENRLRLEYISQMPHLQRIFQLPSGTVVANQAAYMGSASGNAADIQLHKLLNLPDQKRWYSAHFVLTSDGGLRGYAAINNEMLVEIKNFRCHFHDVSASSSELDVMNSLSDVTSSLNAYNSYTNAAWKPFLMLFRQGAFRFVLLTSPSPLPTEILNWKDKLERLMVMSTTGNSYNSSFSVSNSDVSFNTSVSDLVAVSMRSGILAPSSQSSLNLHQGSSSSLALVSTSTGATPRSSSSSGSASSPTRGKLQARVRSIRQRTKTGLNVTEGTLSYYVVDLLKDFPKVPSAVVWQTIRDKLREKRKAFRAEIYRYKLELFHYHQHQEQIKQVHVLDKFREFFTLERPRRPHFRSLISNRKMEALIRQTVEQVKQTTPSNPKYLVDATKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIR4</accession>
    <name>A0A8K1CIR4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIR4"/>
    <dbReference type="OrthoDB" id="71992at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="152" mass="16621" checksum="9B6B41E63AA7BCF3" modified="2022-08-03" version="1">MADLAAIVNLVNSFALSYSFEDAEKSVKDLLSYFAADASFTEELVGSCSSKAEIEAALVELSGLKFLADTRHLPSGHVVTLVDANTATVKSSSVVYWKCVPVMVVKWTDEVVKVDGAWLFKSRVAEAVQKNLEMIGEMQLRGKKQYAHKDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJH1</accession>
    <name>A0A8K1CJH1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJH1"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445297" description="Peptidase S1 domain-containing protein" evidence="6">
        <location>
            <begin position="28"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="235"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="502" mass="54929" checksum="5A40DCF521B3EE1C" modified="2022-08-03" version="1">MQLKRFDVSLLWLWLACVWGSLQVTQAYPIVILRSSFRPHACAGVAITTQHVLVKASCVSQEELVSAFVLDLDDEDTFDDASNPPEDQTPVASVITLPGSAGNRLQVVTLRAPLALSPVTLPIQAAYPTHMQTDHDASILTVNLNTLRVTDVHGVTYINGSTCEEQVCALPAEIEARDVLHEPNQLSFLFKRDPVSDNIWLLGLGGDSVTNRDGIWGFSWLPQQLTSSSFSNLGVHGVQTVKSVIKEAAPPTTMSIYREFLVGVRNASNSSSFCTGSLISSRYVLTAAHCHDKSTIAGVSFPQIKLYKQPGEFIRVVRTVKHPAFGYLFNNSVMERRTYYFDLMLLELEHSTTRTPIKLITINEISAQRATMYGYVNNTAANPPKEMVYTANLPIYFGQVYCNNLLGISTLDSEEYMLCAGGQPGSLPCLNETSGGPLVLAPQTLEQHLLAIGSTGLACGAVPRYASYTRVTPAVPWINEEIKKVTAAPNKTKKPSRHLLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKQ7</accession>
    <name>A0A8K1CKQ7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKQ7"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="193" mass="21599" checksum="2C9999C6FAFBF22A" modified="2022-08-03" version="1">MADEINQDNETPVATIQVTEVEPTKSPRDDGRKTLKKQGSSFKEEMRAVLTSLAAGRLPPLTENPPRMTIDPAEEAEMDSTISISTTMVTVSLMLAVGLIIPIFWCLRIDGTVSWSWAVTCIPLWIFDVFICTSPCLVPPTNTDGTPWTLPRQVYSFFTFVLELLTHVFIVKKLETSTGLWRKCLCRTLCITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKT6</accession>
    <name>A0A8K1CKT6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKT6"/>
    <dbReference type="OrthoDB" id="111925at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="42528" checksum="810EB15A0D00EAEF" modified="2022-08-03" version="1">MTDATRTSSESDDEQLVVDETVDATEDEPRPRKKYKSTYYMRKDEISSLQDEVKQLNATLTELRGDVPEIDTTSLEKVCTENARLHHDLLESDVALARVQAIWSNETATHLRNPLEIFISLAADIEQRRAILNALRVPMLDRGMKYILERTRDMRLDQSQRQTHTVSASNGDHVLIQFDVTPFPNASGVQQVFEKLRFALVNQEFEFWEHLDVTVVCESDGLEMQEASQTHYLVSTPIGVEIEQNFARFWHFSEPSEHLDEPHGVFVVNYVEEDALYPFHPLSRVRIDVSSVLLVRPYRTLGENGTYESGVSVVRWGFSRLLRPQCGLSPHLVQELVDMFPRWGEVIRKELRRHMALQLPVLPSSGMHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKU8</accession>
    <name>A0A8K1CKU8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate Permease (SulP) Family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_009277</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKU8"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF2">
        <property type="entry name" value="SLC26A_SULP TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="533"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="726"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="872" mass="97030" checksum="1C94F8523E1B2781" modified="2022-08-03" version="1">MFSPALSGAARSRLRTPRQQQQRQQRSNSAHDGGNARFQRGSWADASSPIPVTIPRDQKRNTESQRLLSRNDNGRAKRGSWTASIDKAKLANALMYGIINSILTIPCMYGYAAIIFSHHDFVTFMPSLSKLVMFSSVVHQIMFTLLSTLPFAIGQVQDAGLIFLSAMATSICATLGESVPLETKVATVVVVIGIATASLGLCLVLIGRFKLAGLVSYLPMPVVGGYLAYIGLFCLYAGLSLSTGLVINDFTSLLQLWNVEYILLSIPGITGGIVLLVVSQRCENMFALPACILGMPLFFYVVMWLCGASISDARDYGWISPDSPPASFIQMWDLFDFSQVQWHVLPQQLTTWLGMVFVVAFSSCLDVAAIEMDMGSQLDINHELSSVGWSNVVSGIFGGYTGSYIFSQTIFTYRSKTNSRIVGVCVILSEFAIVLLPLSVMSYVPRFFFAATLIFIAIDLMVEWLIHVYHKVLLREYIVLWASFIAINWVSLELGMLLGIGFAILNFLLGYSQVKVVNRAFKRSTAVRKYAARTLLAQKRDAIVYLELHGYLFFGSSVRILEDVQKAVHVRKMNAPEVLRPAQRNNSFAGGKYAMPMTPILNQHYEVMVECLDGSPALEPEGLATEFVVMDFSRVSGMDATAARSSFMILQQLCKRHGITVLFADTLPEIQHMLQQNEIAEPTDFFPTADIALEFCENQLLEATEPTSHLSVTELDLGIQTLLHRFMGEVDNSTYFEGVERFFKRKTAPEGHVFYRVGEFPDSFFFLASGRVALFMNQDGSSSHEKTLHLLEHVIPGAMFGEVDFFGRQSRLMAAKAMNKSVVYELTRTHYEAMQRDAPDLWNRLREVVIHSMALAITNTTCINSCNNAITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL08</accession>
    <name>A0A8K1CL08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008213</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL08"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:001160">
        <property type="entry name" value="Homoserine O-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="88"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="397" mass="43560" checksum="37D68F9DE2C7C2FF" modified="2022-08-03" version="1">MLALLRRVPVQRYTRGAPRHAALSALASPSPVRQQAELEDEYKDAGHDDAQSGVYRLPDALHLEKGGVLEGVEVAYTTYGELNAARDNAIVLCHALTGHSQVHQWWDAMVKPEWTDKYFLVCSNILGSCYGTTGPATINPATQRPYGPSFPAVTLRDAIRVQKKLLQDGLGVQQVRSVVGGSLGGMQTLEWGFIGGPDYVKSVVPIACNSHHSAWQIAMSEVQRQAIYMDPNFQDGHYDPATPPHQGLALARQIAMISYRTHAAYRDKYGRDVVETQTPTKHPQYQVQSYLSYQGQKFLSRFDVNSFVALTHMMDMHDVGRGRGGVAQALSTVSQPALVVGVETDVLYPLAEQLELAEQLPHAAFHSIASPHGHDGFLLEQDALAALTTEFLAKHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL43</accession>
    <name>A0A8K1CL43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gamma carbonic anhydrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL43"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF29">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27390" checksum="C931F94D8346D42A" modified="2022-08-03" version="1">MLKQSLEVVGKSIRSLGQSLDRVGVTLEGKLSYTEHLNPSTRLVANTGRAPAIEKGAFIAPNAAVIGDVKIGKGSSVWYGATVRGDVNHITIGENTNIQDHAVVHVAKIHQDLPTKIGSNVTVGPSAIIHACTIQDHCIIGTGAQVLDGAVVEAQSIVTAGSIVTYNKKIPSGQLWSGVPARFLRDLTAEEIEFMKQCSLEYAELSQVHATECDKTFEQVEADKHRLKTLENVGEAGFPKESDDDKNRGLFFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLC5</accession>
    <name>A0A8K1CLC5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLC5"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="11"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="55238" checksum="0F74111B912C3EE0" modified="2022-08-03" version="1">MAAVAPTFDACGVHIVEDPAKGKVVISDRSFEAGQVIFVEDAFVYASWSTNVCDGCEEDKDDENAPCHCDRTGSPKEMYTPALQKDAVRRDEIVQTMRELEGIGEVDRARCILKCLAMFERDPKSLDEVFECACANVDRCDEEATELRNLVPEIYPPGFTNEQMATLIGVFNTNAHELENLGGSGLFLSACRMEHNCSPNCSFTTYDDKLWMTAIRPIKEGEALSIDYGNFFYRPTEERMTSLFETYGFVCTCETCTVQPDTCRSFKCTSPSCTDGAIWPYPRKSEQPIEDPEELEYDWKCGDCGHVPTDEEVDSFEAAEQELLENDLPETVDGVDEYVKTSPLHKRHYLLFWALDAIGCEAAALSSVAEEEEDQKQLAEVWKRIIEYMNVVVPYAHHEKTIYYDNLAQVQVVLGNLNGARDAYRQAYDISCIVSGAECEPTLKLKNLSENPPTTAEEVRKLYANVKRREDEEDDDEEWEDDEEEEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLK5</accession>
    <name>A0A8K1CLK5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLK5"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000042">
        <property type="entry name" value="Gar2 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675">
        <property type="entry name" value="MUSCLEBLIND-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12675:SF6">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="118"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="540"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW65737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="598" mass="66022" checksum="5278BD6FD55E2E92" modified="2022-08-03" version="1">MSDTDLWRDRNKVFVAGLPLHADDDALYAKFRPFGEMFQSKVVYDAKTGRSKGFGFITFCEYVHALEAVDKMNQTKWENRVLNVRFLQPKAGGDANAAAPVAARRPAKVFGPCPEGCTTIYVGNLAYDITEEVLRKVFEKCGDIKAVRFAEHIETKEFRGFGYVQFYDSAACEASVKLDGMIVMGRPMNIDYGQRDEVSEKAREELQKKLKKGVCHKFQSGECTRGEDCKFAHVLKDQDAEELLQGRTSTPAATPVAVPTPVAAPTNDSDAPVCINFQKGKCKRGDLCRFQHLGATPSTASPTTVETTDVVMAEPEPEDDAPICQNYQKGKCKRGDACRFRHVDASATPSRPPLVRTVTPVAAPVAAPVVEEEDDGTPICQNYQKGKCKRGEQCRFRHADAVASTPSVHVAAPINEESMTTAADSDAPICQNYLKGKCKRGEQCRFRHIEASSVPVVVAVPEISVCQNFQRGRCTRGASCRFAHTTDAVATAAVVVPAAKATKAAVSGTDYQKRFQSVCYNWQNTKSCARGDNCPFFHEGASAPKADEENDEDDTRKSKEKKDKKKKKRKAEAESDDEDDQHKKKKKKKKKHESDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLP6</accession>
    <name>A0A8K1CLP6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_003696</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="167232at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="1343"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="241"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="351"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2031"/>
            <end position="2080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="47"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="475"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="726"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="976"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2062"/>
            <end position="2074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2080" mass="235821" checksum="A73900E2EAAAFB55" modified="2022-08-03" version="1">MLLTDAQHELSTALDVLYSTTQGRLLTHLVKQLTRLAHCEEALRLTLLKNEQLHKDERQQIAALERERDELNARNSTLQTRMQREKKGREEEKEWIAALWPDDVVMPTILRPYEPERPSTTRLVSQVEIKQERQHLQALVNRRVSKERVIQQLELATQWKVVVVLPTSTPEGERIPGQTYYQNAVTGESSWDAPIAMLYEPPGHWDAAKMDWKASYGLEHFYPTEDDDKKLIETRIAKGRMQADEDEIGHKQVGRVVNEDEDKDTDSEADASDDEEVPRNKASRGEDDEEDDDEEEDETPPADPVALREELTAAFNQATQLQDAVNKCQLLQRALAIQLLNATRENFEQEKEALAQEDEENKSVERKKRLAKQQEEMAAKAAAEAQERKNNTVQRKFAKDSVGTKGMTLAKDDELLEKELQEFVLAQRADRNYLAAPITKDARVKFHHQFDEEFVHMKQIEEQVLAIEQLEFDLLEKSALRHEEAIAKSEELKQRCEDLRARQEEVQEELVALQQRIAELEVTPVSPGTPRPTDEDMEKARERELLIDNDDDDNDEKKEEETDEELSREIIQAELGSTRMSTTEVSAIMQEEEELKRLKRCVKSEKRWKQWEEKEVLRLEVLAAAYDRFQILEAAQRRCIVDLALYEADEQYFAKLGIHEKVLNEMMWKLQADSQVARAHFLIERAAREESIFQVKDEYDAVVVKLDEARRLPRQARNPLEHVELLEASRVQAEELQARLTKLQERYAKEQEAKALHMALERRFAGYAFEKMQEELRLFTEKQALWDLNIDLQSELEASRDALERLHLAVVTGSHEGVDELEGDKRSPLEVHEDAVAVFDEKVKRVESVRQFLFLCYDREARWRALASIALIKDTTSDEWMTAMQHERQDQTLALLQKQHEHELQALQKEIKLLQKVQILLQCQLKERDEKIERIQHAYQASSDAVRKETEQIILGLKKQLELEELRHQDEQTRALDHRTRLIQEHEAARSELEQRVVALEDENDLQWHWLTSAKRELHAQRIANEELLMGYASLEKRRASETNEMRFRISSQIKKINNIEMWNLSLKIQSKEAHRERIEMQHEIERLVAHHKQQQRLLRLENWKHRVTAQAILTDVTHLFAFFAQGLAVLAGTTPQANMALRENGGIELLSVLAKHSCQSQVRVIAARALGQLAWNTNATPRALGWQAKHLWFQWQDRESTRVLQELASKQLEFDSIASEDSNEMNWLADTSHSGGIGETDADWFEKDQAKSKKKLVFLQAWNARDAAPHPDVNTANQEYIGLAAGVLKTLLDLCQPSPSLALLDPAMDETTQRQIQRNALRSLAITVMNTRNTAIIGRMEGCIPLLVRLIRAPDSMQVDATVARHAIHALANLAFQNEWNQTQICHHGAVSVLLQFCASHTDVDVLQASVQALVNLSCDHISSCEAIFDAQGIAILTRLCHSYRIHDAIDLALYEEIQSAAAEIISNVVTMLDADQPPRDPMHWQQQENVGPEHRLPPTIERNVAYAILAANELDVFPQEYTSTASKTTAPPGVATFVLMCASCNRDVAFHGALVLGSIAQHDEVRAAIGDAGGIDALFLLTDRRQNASHVAQATWALANLTWNRENQYRIARYLDALYRICTFRNISSENQAAADDDEDALVRSEQIREHGFCVLANALFYNDANRQLVASQSSWMTLIDRTCRHERGNMLEHAARALCSLSYSDPVALAMGAGGASLSLNHPLIPAARVNGLELFIRLCGNAEQPMVQKHGLYGVINMCLHDSNKSKLLEVPRGIETLVNLSGNTNSELCEPALEALDLLADLRIVQQNVLGSGPTAVLSPSTMSSLAATDLKKLIAILHESGDPALVAMASDAIADEVWKKPSAKVKVRNEHGLEKLMDLCVRPASPILHAAASTGLGNEPQKVLTSCLWALRNTIADNVRNQDYVGALDGIPRLLLLYDRHRLHEDVVEAILAVFVALVMKHPLNSQQLVRSGLDMLLRLAEGHGEDDDGRDEEQLNTRQLENAALARELLHLVAPYNIPPDQQTLPPLGPIKASGMSSLEKPSRLKKSVHLPPVLASSPLATTTSPTKRSSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLQ6</accession>
    <name>A0A8K1CLQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Peptidase M28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_009173</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLQ6"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000008">
        <property type="entry name" value="Endoplasmic reticulum metallopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053973">
        <property type="entry name" value="ERMP1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053974">
        <property type="entry name" value="ERMP1_1-A_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22249">
        <property type="entry name" value="ERMP1-TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22248">
        <property type="entry name" value="ERMP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="550"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="16">
        <location>
            <begin position="167"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum metallopeptidase 1/1-A TM" evidence="18">
        <location>
            <begin position="419"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum metallopeptidase 1-like C-terminal" evidence="17">
        <location>
            <begin position="647"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW65006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="877" mass="96408" checksum="01D5C89EFA27C70B" modified="2022-08-03" version="1">MSDVRQRRLYPTDGKQQEIPSTWGDDAPRRKAKHHTSVPNVGPLVVGFLLFYAAVASVIGYYVTWLPEPAPLDAPADQFSEARARVVLEKIMSFGYRPVGTRANEELTPAYLLSQIEAIKAAAPSDVLIEVDIQRPTGAFGLDFITQFQNIYANVTNIVVRVARANLTPEDFNDSLMISSHYDAAIGGAAASDDGVNVAIMVELLRYFAMVPPSHASLVFNFNGAEETIMQAAHGFITQHPWTKNIRAFINLEAAGAGGRALLFQTGSDELALAYAEGAKYPYGSIIAQELFQTGVIPADTDFRVYRDFGAVSGMDFAFIANGYVYHTKLDDTSRIQQGSIQHLGDNLVGVIGRLTNVPGRLQKVAATPYTSNTLFFDIAGMVMVSMGRSAAVTLCSGVALLALVFLARSKVTMQQRLSAIKFVLGCVAMALGASLATACIMTLFAPISWYSFPYMGGATFMLPALAAMTHRLYIFVQKQSTSSTESLWRVEETLFEGMLCTYLFGLVALLSANVLSAYVLAIWVFFPLVGQVACHFLQQAGLLSSSMCIVISLAAAAFPVIYSGFMLTIAYQFFIPLLGRCGPVAPADIIIAAVFGLSLVVMFSFTSRFFCFLPTKQLASLRNLLIVASVGAVVFASLQNPYTDITPKRMTVQHVYREIMHPNGTIQAQDAGVWVNGLDFRGVSTIKPFLAKTQWKDTTLTAPPRFLLDKMELYGDLPWTLPIRDFLPERHSWYLPTGVPEFTPEEYQPSLGVVSSKYDPETDRRMIHMHFTGPSHLNIFIDAERTRLTKWSLGNGVEGPAASQTDGGTYILQFCSGTSPSSFHFWVEAETNNRIEVAVVGHYLEKRTPEMKELTGAFPKWVHSIDTVSTWRIQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMM3</accession>
    <name>A0A8K1CMM3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMM3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="710" mass="80541" checksum="23B12F89B376047B" modified="2022-08-03" version="1">MTDASAFETLLQPVWSAFPPDQLRIDHDVAKRGLRKELYGFCLLIPACDTERVETEWRRQCEAMELLLLASVVNPRELARLARKHLELVSQATHPVTWSHIGQDQDVPCRLVAEVGCQQTRRYQSEQLSPQWAAHGLSLLLASKTRVSERSDLSEIREKLLEMAPTPSVRHEWEAIKIPVCIRLCCKRDDTEVVVKYLRTRHRRQEGNASPFYTESVELFNRKYLSPKKLSHSMVGWLQELSAAGLALRWVDCDDFLDDRVAVAEAMRAITGASNSVIQGNLTYSMGVQVSELWMESTGNYISMCTGLMHSRGVEHVTMLIDTECPKWYWALYALFHASATHSIRSLTTCNMDFIEDDFREFIQAPQPLQVMYPSDQLPSAPKTGSFVVLNNKSRIYFDQHRRDEDEYVMASSIETPFRVIGANGDLTSVLVPCYGECWVCTSDIVSTQPDPFESDPDKQWNLTSHGITHLEFEFGCVWPTVENLGLLEFIGQPVTSIVLEFPRDNEGEVFELDKLWSFCPNLTELSIKRLRLASLDAFVQAYETGMCRLTSLHILGCDVLAQDGVAAFTKALGNPSTAISRTLNHLRVSLLYENRVPGGEVAQMFLSALQTNRRLSFFELQVYDDVLEMYTDEFEALNGSCLNYVSYPLPIRTTCAFLSVVKHAQTEAKDGPLARMDTFVLSRILDLAAEAQRRSVVLTERTHMFEELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CN90</accession>
    <name>A0A8K1CN90_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CN90"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000016">
        <property type="entry name" value="TBC1 domain family member 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="96"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="31174" checksum="DDE45DF549C4513C" modified="2022-08-03" version="1">MLYEPSDNDTIETVTAEAERLLDEEIYNQEMEDFYGFRVPPSGTSTWAHLRSYFDCRGQRRIAEWEDAFGSQFFSVMGCRPPGSDYATVQRMARRGIPRHWRQRVYMAMSGATEKKESEASDYYASLVAQLASRDSVSFRQIELDIDRTFGHSHTKIATEARRSVLRRVLKTYSMRNPAVGYCQGLNFIVGFLTLGVDEETAFWLLAVICEDLFPGYHIPTMADTQTDMLVIKQLIAEELPELDEFTSDVGLRRGCWLRSFFTGKRCGWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNE1</accession>
    <name>A0A8K1CNE1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNE1"/>
    <dbReference type="OrthoDB" id="10684519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431871" evidence="2">
        <location>
            <begin position="20"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="794" mass="86517" checksum="887F349B49F4D28B" modified="2022-08-03" version="1">MRALCGNVALVMALSGVHASESTLVVPALLDIHPVVVSLDLRHSIVDQLAGFCSEHHVDPRRCHVLRGALRDVVELERAPPCRWISQDQGMASFMVVKSLFQTSTQSETAFSWLQDDAFNIASDLCGFLESNAASDATGVESCAASLGAAIDQSSRWINTLSLCAGEKQRGPISVQVHEAPIEHSGLILMTNPSTLTLSERISAVERLIASLSVPVAEGNLDVAAEDSAIPIDPAKESELENMEQPNPFVADEISKPEPEAASVTLDSHELPMVNSEAASTPEVVESVDLGEVLSDVQADVAVDEPPITITPIGPVLPMLDDSTDSSMIPDEIIIESVEKAHDQAAYEVQDDTEVPTAAHEQEAVVDAAPTSDDHHAQKVGEDETLETTLADLVTTPAEDEASELKIANLQEEAEEPPLFKEVLEDEEMGNFDQPAVTEESAALPQDSELEDASTHPEQQRETFDSQDVVNRADATAEHEAIVSGIDAGLVTNAEVGVPELETDVEDEVIQVDSLFDTLEAVTILTSLLLVFYLVLDTVAIALEHFRTAGYVQRSLKFASSGSKTALRALRGRMNVNDWVKQISMVIRHEDRHLAALKKLFTLHRRIQARSAVHQWQHKIEECPSEQALEPASAMPIADKPKQSIPRRPASLNVAAMCLRAGPLAPYMLKSANHRSDSQKALMLEQLLRDPAALASICDDITTADLIRTHRRRVAARRIQRLWRQWKSTRSSPSADLKLSKFIVIAASASAKKLDPEPSGFARILNVVKQSRKLRIKTQPKRPELLRRASASTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPB1</accession>
    <name>A0A8K1CPB1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPB1"/>
    <dbReference type="OrthoDB" id="109637at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="182"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="45515" checksum="56967CF3ED60D099" modified="2022-08-03" version="1">MQASGKQLTHAKNTHRGLSRPGCVFWEEWLHLVVMNGSNAAVSAIRSLHADFERKGIVVSDGEGGSSAFELDLKLQRLITRLKDACKSDKQDLKDVASAIQLWKERSLHHTLQTLDRFGAKANDNGGSAREEQIQAIELHEKAGREINDAVFRVVQQLLETINRQIEAFSVQLTTTMRELIKPELEEELAKEQMMVHRLIDERQKLTQQHSTLQEENTQLTERIDVLENSLDGGGGGDAILCRKLRLQVRELKETQQTLESQMQVMQQEHERWRWEVTQVREDMERQQKTLWMTKAMHDKETKQLVDLVHMKEGRFQEVMTATAQATKDTSLLSPIALYDANSGQSIYYKSPQKPEPSKPKTRLVTLGPSSPNGRCRLDLGRNDGPVESTRTCESSWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPH2</accession>
    <name>A0A8K1CPH2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPH2"/>
    <dbReference type="OrthoDB" id="164904at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="67463" checksum="05F09A2316377A46" modified="2022-08-03" version="1">MASTDVFFRLLSRLDASVLQDHCSDVVDDELRKIQRSLREVKAAYERLQEVREAVAKLEQGRSDVRRSASLHAVVESTSVLHSDLSHSIDRVQLHLASQPLVKRKAHRKESTREDTEPAEKKRKTKTTEHESSKTPKKKKRKSLEGIEIKREPSLPPPSSSSESESDYEDNRVPAKPTTSAKDKKRDSRDDPHNELRAIDERDREWHAAVSRCLKFATKCVRKDYLPVSSLSSICEQVAYIVDGVHSTPASRFADFFTAEFRNVIGTSTRVFKEQASNPTTAPVVEKFLAVMDPSKCESNDLKKLFKRCVTDLRMIRHPDSEKTPRPVPSKSPKDTDTPMMRLLTGAHGVLTMRVSERGNQAVTLVRGLQLELRRDFPEESEHANPSKEVYQTAADATKLVIELIQDEDWPSANESAYRRLLELLHAISSRYIIFKQLAKRACDDLNAYLSQDKPPSSVAKGSQNEQKAPTKPKEQKKSSKMPHNEQGLIKQVESSLQSLREWDDGVFSLKQFDQQVVQILKRVVPYQSRTWDVSRVAELVSLAIKRANSIQKQEHRYTRLAQLSRFQDQIAKRSDRASSNERERKHSRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPN7</accession>
    <name>A0A8K1CPN7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_003878</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPN7"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="486"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="750"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="781" mass="89187" checksum="79DB32759BC09E67" modified="2022-08-03" version="1">MDPMDGSDVVSTTSSSHESRTTSVSSRNGPQLFRFFGRRPRNATDSDSSLSEIPASSDDEKFRMERVFQEISGNRRRRRHRHESDDTTFSAEQSFTYVGSSSHLTEQSRTSERRRRRRQRPPTTLTSSTTASTAFPGIPQEPEPEEEDDDELEITTEYLDAMLVKPDDQVLNKYTRFFLDAKLEELYQEYTAINWFTWARWHVMMWTCVHIFVNLLFIIMPYSGFVGMDVFVLSFTTVPAWIQYAYLGVAIPFAILPTEANPFQKSWRSWVCFILILFNFTFQIWIASANKLAVDQVEHAVDPLFKCIPSNSTASNGTVVVLTDEQLAVKTAVQKATAYHVTSIYAGALVQILAGFASLFSFVFAVSIRLEFVQVWFVVLTAVLTYVMVIGFYRLQLEWMTAISYLFAVVLLFMLSHSSDRNNRRSFLSQLLVEKENESLKSYLNKAEAVLMNDAALDQEKQVVGKMLDDPQLEHLELVRIPFSDIKFLQAIGRGAMGDVIKAKYYGTIVVCKRMRRENITEDAILKFREEVELMSSLRHPNIVQFIGATWDNCSNVCIVMEYLENGDMHSVLHSNIGRSFTWADPLLKMAIDAAQGMLYLHSQEIPVVHRDLKSVNVFCSATFGCKVGDFGLSRRYKRDIDALTTLVGTPFWLAPEIIRSESYGPSADVFSFGIVLTELETRRTPYHDQEETGLKVLMRIAENKLRPSLPPTCPPRRRQLILDCLDGDPSRRPDFAEILRRLQGPVQQEIEESLLRPPRDRKRNRKGHAGSIGTSHHHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPQ8</accession>
    <name>A0A8K1CPQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPQ8"/>
    <dbReference type="OrthoDB" id="157554at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="331" mass="37331" checksum="CE696A274077DD7B" modified="2022-08-03" version="1">MGVAEAAPKKKTRSTAQARKDEIRVLKAQLGPLSERLEELQHAKLLEGHDNMDDVMLENALLRSGLKQTDLTLAGAQSLLASSRAALGRNPLDVQIYLSAEPTLRHQALATLRDARLREATDFILERVRYLDLRRPHQEKEAFELPDGDHISLRCEVVPFRTNASVKQAFEDVVMAVKQEEFTVWESLGVTTTFESDESPDLTYSQARGISTTPDGTQFEKNTAHFLMYSEGNNQLSVPHGLVVMHPIAYDEQFPYQPQFRVREDVTVVFLVCPLPGGGVVGIRWAHMRIHKPLCGITRVQEMRIRDISARWGDIVRNNVLEAVFGRMLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ15</accession>
    <name>A0A8K1CQ15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ15"/>
    <dbReference type="OrthoDB" id="111435at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="437" mass="49548" checksum="33334902B9E897C3" modified="2022-08-03" version="1">MEDQLIAEFGQLVLQRPTTIEFTNEQEDFIERAVKNRQNLLLVAPAGYGKSAVIKEIVNRFNNERVLCALCASTGKAALLVGGRTLHSYLGIGQGNGSVEDWVKFTRSMPYMRNKLSELKTVQVILADEVSMVSAKFLDQISEYLQKIRSDPKPFGGVQIILIGDLCQLPPVKGKFIFFSAEYERAAFHPYQFTRCFRQSDDPKFIELLNEVRFGRYSEETWKTLSNRTSIDPEYSNGLTPMRIVSRNDEVDKINEAELNDFLAKQKVAKIKYAVRNIDDPKKVKKATDYRKKANIPEFVEIAVGCQVVVTQNLGQGIVNGSQGYVTTTGSNWVQLRLHDGSTARIEYVQFKDPELPHMITLFSYMPLRLGYASTVHKAQGMTLKLLEVDLKNTFAHGQLYTALSRVTDLRGLTVKNLTPRAFICDKDVLEFYKRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ40</accession>
    <name>A0A8K1CQ40_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ40"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="385" mass="43741" checksum="D6B487FA8C82D783" modified="2022-08-03" version="1">MAPVAKEGLPWIRFMNNHTTNDGLKLVREALLLTGAMGTYVGTRLHREWKRKMDEVMLIGMPFWRLGARAPVPAFNVGGAFTVNRLREWDAMMDVFLGYDELSESFEEDWNQLCATLQEHDLSADHPHEIPIHVEFSVSNNDDAHVEELQIIISCLKKFYQNAATAEQLHPHRPRFNLKAVRLDVRGLSITPQTIPRLLELLALDIPIDRLIMPQVFPHQGGLPWRDAWASVLFTVFGHPDAKVTTGRPIKSVLVEYTLEDSFCAFCSVLSQASNVQDLSYYGPSDREAPKWKWLYYALLSKTSTSSVRSVTFHKFDDVFANSRDVNPLKAKHPHTQLLDDSTLHDDVDFGSIHLAKGTVIRFFPFGQHDKTVIEDPDGQVVQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQV7</accession>
    <name>A0A8K1CQV7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipoxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQV7"/>
    <dbReference type="OrthoDB" id="75140at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462656" description="Lipoxygenase domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoxygenase" evidence="5">
        <location>
            <begin position="240"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="567" mass="63339" checksum="CC56589EC84934D3" modified="2022-08-03" version="1">MTRVWVWMAMATLSVLDPVSGLSLPSSSDRSGLRADAIAAVANQIVDTKRTYPINGTVYPWYDGPVAAPGSLTQQIQYQEFVKLASFTTPQAKELASLLANSSSTTNLTSMDAIADLYNGAAPIIAKPMAMDNSDETFGQQRLTIKSMAIRLAKLEDIKGKPFALSDSQLTDKCGAGINRLTMWTSNRVFVEDFSNVAQWDDAANPNKYTPNVVGFFCYNAVTEKLLPIEIRFPDTNLAYTPYDTKDEWTLAKMGLEAASIQFHQIQHMAETHAVTIPIRVEMMRHMSAEHPIRALLFHHVYIDFSLEMLVASRLLNTSTGLDQTLAWGASGSVRFIQHQTQTVVSLQNDFLTDVRKRGLNYLPNQKFVRYGTLYWLTIGRFVSDFVNTYYATDADVQADFELQNWAMGCTGVSHLHDFPASFTSREQVRELLTHLIFLSTVRHHAMNGVVTWHSMAVPYSPAALWKALPRTKGETVNLLEYTLPVRLIPVSLDLGALFFRPPPASESLTSAYKTTPFSDEPLLQSAVDTFHTSLGAIDSLIVTTEKSEKWPYEILRPGNLAHYTWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQY2</accession>
    <name>A0A8K1CQY2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQY2"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011498">
        <property type="entry name" value="Kelch_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07646">
        <property type="entry name" value="Kelch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="623" mass="67183" checksum="8774141C1E768B04" modified="2022-08-03" version="1">MVKPIPWQLSLRRTTREILAGLKSKAPRATKVTMPLISYEGVEVDIPATLSGIQFAFANGALTIQCNGFSGNIVLSKPVVAAKTLSPPMTLSDFPSMPANPVVASPGIPSSGSVSSLVVSASKKRSIVDEPSDLDTEESDGEALHKRIRPNFLNDVEQTMLLAQLEASQPSQRDTIEEVDSLVSSTASPERSSSAEDAPVDFKTPAKPSSATKSKKPTPKKSFFSPDPKEPAAKKSTPESSGKRGRPSKSKSDSSSTQISIRDMMLQVTPNKPPVIRSAAASWSLVDVKGTPPVERWGHTATRISENRVVVYGGADDDESTLGDLFVYDLNKNEWSRPLNCESIPRTWHDSVYLESKRLMLVFGGERNMGGDQMDVLSDIMVLDTDCFLWYPPAISGVAPIARSGHTCTVVGNDIVVFGGSRGRSRQSSVHVLDSENWNWKTVKIEGKPPTARTYHSGVAVGDSIVYFGGNDSKKSFNSVHVLKKSTTAPDTWTWFHPCVVGAPPCARTGHSATLVDNSKILIFGGWDPQSGANSMATRVFDDGFLLHTETWEWEPVQVEAKQTGSDKNPAIGRVGHCAVMADDHTVLLLGGQDTREQRLGLVHALTFSPSKDESGSASTVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRD3</accession>
    <name>A0A8K1CRD3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRD3"/>
    <dbReference type="OrthoDB" id="444540at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051581">
        <property type="entry name" value="Ca-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524">
        <property type="entry name" value="CALCYPHOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524:SF6">
        <property type="entry name" value="CALCYPHOSINE LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="101"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="426"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="512"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW67340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="578" mass="65768" checksum="B6018B7EF812221E" modified="2022-08-03" version="1">MKGSMLKRSTRKDAKKDNRWSPSKISFQDPVGHELPPSLQSFRWNVDKVERKLQEKIQEKTKIAGNFVYQQAYRLLECTRGEGIDFVSFKEQLRIKFGIILEDGELQLLFDKYDEDRNGTIDLNEFIRRVLPPDYHYGRQWFELSQQHSEEKQAALKRESRNEFLMGMGIVKDDIENTGETSNWTLETLLKQIQTKVVQKTPSGDDQYRRAFKMLRSGRDQGIRMRELRNNLKTKFGIFISEKQMKELFSQFDMDGSGDIDLKEFLQWVEPPAYPGNSKVPRGIWTVEDSESGEEEDQEGVVEETKGIYGRSFSEMDLHRGCNNTNLLGTPPLSKMPVKKERPMSANPKKAAMLKQQREQMSSTPQLLEKHLRDTEPSSPEGRHSVAKATQTRRMTMSLADIHADTRLEKVTPVNNRVAVDAQSVYSASSIASSRPRSAGSVASSRPSSAGAGMRSASYMRRPSTPQNLRQKCLESRLAGAAAEVRKDPAKAKKRASVGPTVKIETGIPSVSKRVSGKEHRRHTFSDTSSIHSREYLEDPYEDEPRVVRVHPKQSDSRPFTQEGKTLFRSKTTSAGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRI2</accession>
    <name>A0A8K1CRI2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRI2"/>
    <dbReference type="OrthoDB" id="182479at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35542" checksum="98E4B91A28810533" modified="2022-08-03" version="1">MTDDASGRRYQLILPRSSTAPRDELLYPTPGQMLDAGPRTATSSQRGRKFRERRRQHMEELEQQVGRLQQQVARAETARVIAHEKALRRRHSASNSSLIRLVREYYTLFQYGFRDAPTYPSDPNGHNSEYKECFLRSIMSEDIVTGDLVGIEAALMQWRFFTFTNANLRVEIKHVDIHGPEEDPSVEISSVMHFITQPTTLILTFPGAEADPELMEKFSSVHLAVPVLTRFQFTPEGTISYEEVNADIISGYRDAGFSLTDISKLMKYSAISAKSTMHRDTILDSNADESIVEAIVRVTDGGIAASCGGIDGIHRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSL7</accession>
    <name>A0A8K1CSL7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSL7"/>
    <dbReference type="OrthoDB" id="10519877at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="154" mass="17684" checksum="2A6F7DB613D04439" modified="2022-08-03" version="1">MADKDANKKERISEDDVSSEDEDQHICSPEQTTCRHEAPKLGKKQPVLHGRCAVAFVKFTRRNDKQARKMIEAVMVTPRVLKRGRDYGSAPQLQERRAKTFAGVEVDRRRPRAQSLRTGPCLPFLDEFTSEDATKAIEDHNQELSFADMRRWSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTB0</accession>
    <name>A0A8K1CTB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTB0"/>
    <dbReference type="OrthoDB" id="167659at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="633" mass="67897" checksum="25BDE6C6B20C18E5" modified="2022-08-03" version="1">MVPVTVGGAVVSSSTSFEAVVYKPDSGDGKQGKLQLTATVYYKDTPITTATKTFTIPKESMRLTAEITDWPFASDSNLLALEMTVSGQRALLLDSVLPVPLSNPKVTEDGETMLKTLTFESGMFLDASLGVTMDGVAKSMPIDVPTDSSKILRKFAKFATKTVCDLALRYEEPVTVVSFESDKDPDGNALIPTVAKFKKGMVTIQFCPNGDCEDGPFVTLTPYIFEERQPASASGGDDVVRRALDLNEDDDGALKFTAEITNWPFAADDNYLALYTLTSGKREPLIKDVTPTYLSNPTLTDKEGDPNTKIVVFDSGMFMDMPLGVTMDGANKQVTVDVPTGTSDIVWKFSTFATKAVYDPVLRYEKPTTVVSFKKGPDGKASISTEASFMKGMATIQFCPTGACANGPYITLMPSRFEEMQPVAGGVAAKSVFDTFNLNEDDSVQWKDAVDLMVNNELVASTTSFEAAVYMFHDDESTIAKLKLTATVYYKETTVTNAGQSLTRTRRSPGEELDPPTIATKPGDTNTKIVAIGGGIYMDVPLGVLDGSNKALKADVVSDTSSIKWMFTKFATKATYDPVLRYVAPTPAPLLPPPPPAPVPVPGPTKGATPAPTPAAPVKSSTSPLMLAISLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV00</accession>
    <name>A0A8K1CV00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV00"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000062">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="242"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="278"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="359"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="476"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="515"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="580" mass="64251" checksum="59FE775A48D418B5" modified="2022-08-03" version="1">MASDESLTPIAILVDELKHEDVQLRLNSIKKIHVIASALGPERTRQELLPFLNDSLEDEEDEVLLVMAEELGNFVDVVGGPANAYPLLTPLESLATVDEATVRDMAVKSICRVVEQMQPEHITEHFVAVLRRLVTRDWFTSRIAACTLFQVGYPRVATTIQAEMRGMFAQLCRDDTPMVRKAAASALSGFASTLDPVSANNDLLPLFLVLAQDRQDSVRIHAVDNAVALARLVSADVLTTQVLPTVVELAKDGSWRVRWSVANRFSEICEAINVDAVNTTMCDCVVALLQDSEAEVRTAATSKVAGVCLFMQPQKIVERIVPCFQTLSRDLSDHVRSALASVVMKVAPFLGRDLTIDHLLPLFLLLLNDQNSEVRLNVISNLEEGNNVIGIELLSQSLLPAIVHLSEDRQWRVRLATIEYIPVLAVQLGRDYFEERLAGLCMAWLADNVYSIREAATVNLRKLTEAFGVDWAREQIVPRIVEMHTDANYLHRLTSLYAVKVLSEAMTPEMVQEVMIPLSTSLAQDPVPNIRFNVAKTLEAVASRLTPAAVETHVKPCLQALLQDSDGDVVYFANRALTKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FA27</accession>
    <name>A0A8K1FA27_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FA27"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22929">
        <property type="entry name" value="HFD_POLE4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF54">
        <property type="entry name" value="CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="175"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="228" mass="25340" checksum="D10466652063CC02" modified="2022-08-03" version="1">MAPPKKPQSAYFLFAADKRKTVAQENPGLRIGEIQKLITAQWKELSAEEKEHYTTLAVQDKERYEREKLENPVELPEANAQDGVEDEPTGNVCIYPLGRVKRIIQSDPDVNKVSREALIAISKASELFAQYLATKSYEQTLYNNKRQIKASDVARAIQTTSVLDWLREDFPDVKPAAATRSNGSKSTSDTATSRKAKATKAGVSSFFQQTANDTADEPMESATETEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBG6</accession>
    <name>A0A8K1FBG6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA polymerase II-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the RPAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBG6"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025986">
        <property type="entry name" value="RPAP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13877">
        <property type="entry name" value="RPAP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-polymerase II-associated protein 3-like C-terminal" evidence="7">
        <location>
            <begin position="355"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="488" mass="54256" checksum="BACEDDFCEF5C23A0" modified="2022-08-03" version="1">MAGADSAKERAANATSVLQVQQQIRANASELQDYFSDLYAWEKTIQKKEEATKSTAMTKQNVPLPRGQKTATVSLTPISAPEAIAPVEGPTKKADAHTYDKGYKKWDKFDVDAALQEADGDHSAEKQSAQAETTTTSLPTKKVVAKPKIGSVPTKSREDIEREEGNEHYKRGDYVAAIKSYTRCLGFNSQNAIVLSNRAMAYLKNREYKKAENDCTLALKIDSAHVKSYSRRGTARNALGKHRLALLDFERARELDPKSKQLLTQIASTKESMRTAIKRAPKKTDFLIQVIGETAGDTNKLNEDTPVENKENSGQIQNTSTKETASKAMAAAQTPPPPAPSTKSTLVLPKLPKKAPSTSYEFGRVWKTLVPKGEPERARQLWELRGTYLRMISPATLPTLFKNSIESDVLCDVFATIRQVFSVTGDGKPFVVEWINNLCKVPRFDMTIMFLSDKEKADIAWTFDQLVKSSAEEESERLQQLKKQFGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC00</accession>
    <name>A0A8K1FC00_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC00"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF27">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="429"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="665" mass="74721" checksum="39B8262036E7E25F" modified="2022-08-03" version="1">MVASHDVPELIPLNVLFGNADKRMPRLSPDGKYYAYLADAENGVTNIFLKPVQWESATSSTLVDTSTAQQLTNETHRPLRHFEWAKSVEPRRILYIQDTDGDEDFHLHVVEFHVDEELHGVDSIQLRDLTPFGAVTVSAIELSDNFPNAVIAAVNKRDPRFFDAYKIDLSTGDCELVVENPGDVNQWLVNDAFEVVGGFAMDAASGSQQLRVKDAQDETQWKTLVEWPHGETCHIHTVAEDGKSVFVETSLSHGDGAETNTSRLVRLSLEDGSVVEVLAQDDKSDVSKVSFRAKTQTVRYVTFDYTKPRVHIIDEYIRADLEHLISQCTGEFELVSDSEDGLTWLYADSPDNASVKYYIFDRRTRRQALLFDSRPELAKYSLVEMTPHVIKTSDDEDMVVYVSLPNGVEAKNLPFVLRVHGGPWARDVWGFHPEHQLFANRGYGCISVNFRSSTGYGKRWTNLGDLQWGASMQQDLTDSVQWLIKQGLADPDRIAIYGGSYGGYATLAGLAFTPDLYTCGVDIVGPSNVQTLFSTIPPYWTAMKRMLELRVGEVEKDDEFNRKISPLYHADKMKKPLLIAQGANDPRVKQAESDQIAKELHANKHEVQYVLYKDEGHGFARPPNRLDFMWRTETFLASHLGGRVLPKDEEVIKGNSAVVVDTATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCE4</accession>
    <name>A0A8K1FCE4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011818</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCE4"/>
    <dbReference type="OrthoDB" id="74382at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="100"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW58230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="218" mass="23985" checksum="97479FA5F4B6D261" modified="2022-08-03" version="1">MASPLLSKSPKKQGYDTLLDVTREENAAPTNASFFSRVLFAYANPMMETGNKRQLNYDDLCELDGENKTSESYAKYKATYDRCNSSVTRAVIYTYGGPFVLCGCAALFSTACSVFAPAVLHHVIDAFTAPAVDMDNLAIWLGAFFISKLANAFVAAQMGFYLELTALRLTASMKALLFEKAMRRSIQSENDPKAVDIANLFTSDVSNVLWAAYQVNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCN7</accession>
    <name>A0A8K1FCN7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCN7"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF25">
        <property type="entry name" value="CYTOCHROME B5 HEME-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="236"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="42013" checksum="B0C3238D01C86563" modified="2022-08-03" version="1">MQSHSAMTKEPNALKTRTGNALVQFLFITAVTGVAYQFLTSRHEVDVSTSEYGGHRMNALPWNDAAALKRHRASRETVSTTEFSCFMACIGLFGLMQRKKQRDENERIETMRAIKRQKAASTSLHVAVKEQTALALTHADVLSALPVEIQLELLDFIPPQDLVSCAMVCSSWNELTGDHASDLWKRAFIRDFHESGERFGPIFPRICWRQYYFLHHLSRAVEVARLMELTANRKCMVIKGMVYDVTDFLDMHPGGYHVIGDVIGTDATDLWYQFQHSSEARTMMADFLVRDDVLMAQKQIRESETDGVTTKTLVLNGNLASVQRKWDHISWYLAHAHIFGGLSSVFLDVSLRFTMRNMKGARRRRMACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD43</accession>
    <name>A0A8K1FD43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_013934</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD43"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="140"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="235"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="47329" checksum="D2FE974123A798B4" modified="2022-08-03" version="1">MSLCEQELRETIHAAFAHYDEDGSGTIDIRELRRLIEDLGGFLSDDELNAAVVLLDRDGNGTIDESEFARWWQSQSADLDGDGDIGTFERTMARIKDAGQIRFRVDIHTAAWRGLTDVVERLLQEDAELAKTRDSTPYGNQNTALHYAAYQGHTSTCAALIAAGTSVNVSNASGCTPLFLAAQQARKPVVELLLQHGADTRIAEREHNFTAIDVCTDDDVLVLFQALSGGAPPPPPTSLRTRVDGSTIITLSWEMPSCDDLTHSVIQMSMDASGDIWKSLNKVEASLTELTISNLFIDRKYRFRVAVESASAGTSAFSSVIVARTRSHDVESKHEASSRTKKVLQSATRILQATRRRPVDEAKEDDDKKSPSPEEDVKGDDGRDAEVVEIVATAAEQKRERGRHHHSTKGEEVDDDDEYAYYSEDDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD83</accession>
    <name>A0A8K1FD83_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FD83"/>
    <dbReference type="OrthoDB" id="341482at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019321">
        <property type="entry name" value="Nucleoporin_Nup88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037700">
        <property type="entry name" value="NUP88/NUP82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257">
        <property type="entry name" value="NUCLEOPORIN NUP84-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10168">
        <property type="entry name" value="Nup88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="782"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW58036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="922" mass="100962" checksum="8722F1E12AA098F8" modified="2022-08-03" version="1">MWTQQDAVDENNWALRADLELCGSIPPPTYAELHADAHLNTFDVSESGHAVLLSERGRLFLLNLFQPPSTKKTASSTQQQTRVRLAHLELDPPLQKDEIREIERVHVNAAGTSVLLAARSWIKVVRIPSEATQMLTNTSGTANGATLSALDAKRVLGTATRSNRQHFLVRFADGTTETVGVDVPKGGVSQQDVEQAASRSKRIASVSREIYCASIRQVGYFNRVRHVAWHSLSDSHLVVLSDGEEISIFNLHHDVTKPEQRHVLNFPRRASSTGASVSTATSVSFCFGSPHMLWDVFTCYILRSDGSIYALCPLVPYDSRVHASVLATLKSEVDGQLARTKKQIEALTSDDDLKGIYQTPTKYATRSTDSAANTRRRLTSTVAELKSQKYWLEEAWAPVSVASAASTASLTSPMHKYTKHPIANAESNSDFYRCVKPHISGISPETWPLAIQGPVDVSPKSVIAGKHNVTGGSVASSVLSVPYSLKHSETMALNPFLLRSYTSGHVELVLLDVPVRPQWRSDDSASTRPLPALLLECLSLGVDDSGGRAVLTRDESDPRLVYCLHSTGVHVINVSWVFALAAGKPFTTLPKSSVRHIFSVSPSSSASEVSVKNVIGVRVIKNVYFGHLLLLRLASGSFEVVNVSAASSELLKGVLESSNVDVSFGDSQSSLPETLASVAASKAASASTSKNSGGKGGVRPFQDIVVEKLSALTARGTRVTGNTKLSEVNDEILAFVIDRIKTLYEDIEYIDVMDQLMKDRLVLDQEMLKTQAEKAVVVQREMKQAQDGLLALQEKVDRAMKAQQNLRKRAAAVLQAVKENQPMLSRAEREFKEELDLVSVEVRRMKPRVTQLTVSGQRLVRNLENLALSSASQTQLRPTGINAISDEKKQMCFDVLRAEAQLIDDAKSMIQDMQTNIQILQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDV7</accession>
    <name>A0A8K1FDV7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDV7"/>
    <dbReference type="OrthoDB" id="71501at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="415" mass="47139" checksum="F59D4B8782874697" modified="2022-08-03" version="1">MTWTDLELDDDPATLRAALEMLDALDESYGASPLSDKTTGSSEATEDSDEQEKMAQEAKTGDNTQVTVRKHRNRRKDELVYLRSKVKQMEETLLTLKRRRIEDKHEGSIAVSRVWEDLAIRQQRQRQMVEFENAKLRVMLGAQLKAGKELIRLLQSTSRCDDEQVTQMVRTSDLNVHHAISIDEQFARVDELYRVSYAAFGAFPMDSHKGTTREIKISEDDPNMISINLCAAWTLPFPKVQVLAATWQSVIQTGPKKNCGYPLARNDDTERMSAVFRSDASIVDKSISGEVEGSLVAKKFPGSALMHDVIITSFNAELIKSLPRSMDDLRFNQDSWIRVMDISHQSELATQPLTQIQISRRVNLHVVTNRSATQRRRAGLLTEFTLAQMENDVIQRQETIENLLFAAKLTATRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEZ6</accession>
    <name>A0A8K1FEZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_000028</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW59986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEZ6"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="338"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW59986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="595" mass="66147" checksum="D689C1B5A942806F" modified="2022-08-03" version="1">MLQTHARPRGRGLVDEQEEAKSSSSTALTPFGLDRSARQIHLHAYDATSRPAGYVEVKIGGHPLDHKRILDTHRPHEIVRGPLKTASSASSTWFTPSRHSPAYEAQERVILEYSPVKIGGHALDHLPFVNRGQPSRPLWGYTPYVAPSVIFSGRPSAATAAFEQVQRGFANLYDCSRCRRLRQSPRVQLCCGHAICASCLSSQSMKHVEHGSSLCFLECVQCSEFITIEAVVFPNRVLHVQVDESVRSLSDLSAQLEPREAALVPFKWKFGGAVGALMLVAGRVMSQLSSPRKRVEVVVDPVDATTAIIDSDRSVENGSTRWKKRVQGLRPPSKLLKYAFVRTLGIGNFAEVMLVERKSHQKKNTPLSVLKESDKLQEAVNEIHLLSKIENPHVVRIHQYFIEEIGHRHFAYIEMEYCDQGDLLRMLQDHGALDSSKFDAIFRQLCLGLAEIHRCGIVHRDLKPSNVLLTSDGIAKIADFGVSTRLESDLLTHHAAGTLAFMAPEVRRYFLGEDVSYDSSADIWSLGALAVAMLTGDPEPRVATRPAEEVAESLFERGVAERHATLVRDMLEADPHKRPSLSTLVEMFPPMSARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF89</accession>
    <name>A0A8K1FF89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF89"/>
    <dbReference type="OrthoDB" id="69533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="191" mass="21738" checksum="EC8ECD9EA734D8A8" modified="2022-08-03" version="1">MGNSLNCLEQCRPHQEQQQRLLVLQQGAHFKRKKYLLGIASGTEKINLRLSNDERRLLWKPVEGQKGPTSISVDDVHLIKVQGSTAFTVVSRKGDTLLDLEAENEELRDLWVTNLQLLCEDSEDVEVSAESAAAGSKFRKMVEERSKKQAYWAQRTQELEDRKKEAEERKKQFAGAGMKYTANAMINRSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG95</accession>
    <name>A0A8K1FG95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_010031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG95"/>
    <dbReference type="OrthoDB" id="2100592at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="57489" checksum="BFA6EAF7427AEA30" modified="2022-08-03" version="1">MVAMGDSSGSSFLLHACILLLLLILTLLQIMFFAFLPEIELHADFCNATVASKTLTAATSPELRTPMHLFYRSLYLSPREIASREKDAREKAERERHAALITDIMKNSPKIRGEKDGAMDAERLTKQETEGEKLDVKKGFFLQAMGQGHDALNSTSTYCINLITPNDSPGVLQDFELYLNALPSSRPVYAFKGHTDLPASVIDLYLERHPIDKKYYRYFNAPHDKTIWMMQNAEFFDRHELANPDVGVMVIKNRIGLKKVLEYRHRHNMGYTVFYTKHTSHDVYQPEIERDWTSFLHLAGWSPFKNTRVILQAWARHPEWPKLVLRVIKADICSWIDETYGPSGEWRLANVDYKCGSEPLDMKNELQNKIGLHLCPSETEGFGHYINEARSAGALILTTNVAPMNELVDEKSGVLVGKAHDWWWQTKGDLFMPLAHVDVEDIEAGVERILLMSVEERKRMGRRARAKYLEDRTYFLNAMAALEESLCQEEVRIDKLAPYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGA5</accession>
    <name>A0A8K1FGA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGA5"/>
    <dbReference type="OrthoDB" id="370281at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="54"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="508" mass="55422" checksum="DFFB03F39611EC94" modified="2022-08-03" version="1">MVVDAGDGSLEAGRMSPVRALEAKKPSQATPKITIEAERAPRHHPERLRAWYAHIALISVAEFAAEASRGLVLPTLFSYCKALGGDLVFMGFLTSLFSGGRFVSSLLFGWLSDRVSFKTMYYVSAIFAILGNLLYILPHSPVIHSKTLLAVSRFLVGFGAGNRSVCRANIAALTRVDQRLQYFTMLATVVFLGYALTPGIGGVFGDIDVQIGIEYFQFNRFTAPGYILIILNLFTMAMNAYVYDPSITREDAPGPHAKATPRLDEAPVDSPALHQSSQQSTISDRMVAIGIVVFIFQNFNTRGILSVFETVNVPLYLRVIGQTNARSAEAVSTTTEAATFYFIVGLLGLVSYATVQVLRRRVSDERFLLFGFFVLMVGNALLLVLCVLMDSAEAPTETNFNLFVVAEIFVWSIGCPLTSAVVVSAFSKVLGTRPQGALMGLFGSSASIARMIMPFLPGVLPSWSWLFSVNMVLCGISMVILGLYLRHLRHNSLGTYSVVDTRSPALQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH58</accession>
    <name>A0A8K1FH58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052506">
        <property type="entry name" value="Bact_Fn-Binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48234">
        <property type="entry name" value="GH09231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48234:SF1">
        <property type="entry name" value="SEA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451606" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1754"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1164"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1359"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1459"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1513"/>
            <end position="1525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1782" mass="179411" checksum="DDAB642E8B1B2DE4" modified="2022-08-03" version="1">MVKVAVHAWISVLLLAAVVGSAHADGGSSSVRRANRAVCSRKPTMYEAKHGVGIVTDVSCASPQLACVTSVCRYCQVNPTPVSQLFQPCPVTTASPALTPAPVPSTSAPVFTPQEIVDPPSPETIAPETPAPETPAPLTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPTPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPARDTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPVPETPAPLTPAPETPAPETPVPETPAPETPAPETPAPETLVPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPVPETPAPETPAPETPAPETPAPETPAPETPAPEAPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPVPETPAPLTPAPETPAPETPVPETPAPETPAPETPAPETLVPETPAPETLVPETPAPETLVPETPAPETPAPETPAPETPAPETPAPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETLVPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPVPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPVPETPAPETPAPETPAPETPVPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPVTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPVSETPAPLTPAPETPAPETPAPETPVPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETLVPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPVPETPAPETPAPETPVPETPAPLTPAPETPAPETPAPETPVPETPAPETPAPETPAPETPAPETPAPETPAPETLVPETPAPDTPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETLAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPVPETPAPLTPAPETPAPETPAPETPAPETPAPQTPAPQTPAPQTPAPQTPALQTPAPLTPAPSSAAASTTSPPASLGPALTTRPSPPVRPPSTPAPPVRGPNGHRDDHHDDHHDVPVGGCTYLSTRHETKYGVAVKTDYSCSRGGSDCVTSQCRYCQVFRSSVSKGYRPCVPTSTSAPTPAPAPAGASASREVCPVTVSSGDAKVGINIVTDVRCKRGGRGCFHGVCRFCKLWNSVQSNNFDDCSVVTAPTVPRGTDASSQCANAVGTDDKNVGISAVKDDSCGRNGFGCFSVKQTKCRYCRVRDTKQSRKLSKCEDVSGGNGNGRVPNHRGNRVLVLEGTYPHSDNDVSVASDDDIVNSPRLHPSIRGESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHN0</accession>
    <name>A0A8K1FHN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHN0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="518"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="560" mass="63245" checksum="9543B09296E64B30" modified="2022-08-03" version="1">MVLNFIHSAFQVALLVAASEIIGVFPVPFSTTLIMPIYAAFCWITRLYVARKQLWDKADVAKALQYRTKLLKLFHMITFIIQSMTAYAVFATIFSHIPAAYQLLMAICLQFLKAWIRNKLWVKAQIHDSGGDLAAIHVATNCSFFHSIFTATCMQTSKSVYTLVFLIMWGVVKDILAFQAIRHRMNEVDRLQCTVSRLSRGSLDTRKARTQLLQRIVPSVLPPRTKSAGALPSLAVESAYIPLRVMAARLRASSSDLNPIKELTPVEIEYLDRLTQLYHCREVLLWRMFTSLFVPCFYFITALAIHQLPSAPYVGFIGMANIHVLSQRIGSQLAVRAVIGLIYGRILRRSGHLRAMDQCLFILEHQFVPLQTGCIIIALGVFAFSVTHYGNDTTFQFEWLKHHAVNTTTSLPATDFQAQVHLPQFYYPPGKAVLLNLVHSAFQIVLLIATAEIIDVFPVPFSTTLIMPVYAAFSWITRLYVAWKEVWDPHDPAKAVQYRAKLFQDFQMITSVIHSMNAYAVFAAIFSRIPAAYQFLMAICLQFLPQGLDPQQALGQGTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHS6</accession>
    <name>A0A8K1FHS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000104</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHS6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035475400" description="Elicitin-like protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23035" checksum="E8FFC5E14CCCEC87" modified="2022-08-03" version="1">MKPSTIICILALAGGSAVSAAECSKKQLKAIAQYDDKIVSACGSDYDGFFASSGSSIAVCKNPACVGVLDSVADEYPDCTLAGMNMANMYDAIARYCKTEGNSTDGSHSASTSVGKPECSDSDKTKVDNLRNDPAMTEICGDATAPKPKDPYAKYCSSECTAYIKEKFIPALPDCTVDGGDVEETNKIMLLYCDMPSAAAGALMSMSTVALSGITVAALAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHY5</accession>
    <name>A0A8K1FHY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF11">
        <property type="entry name" value="FIBRONECTIN TYPE III DOMAIN-CONTAINING 3BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="730"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="888"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1022"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1265"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1301"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="1403"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1107"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1703" mass="191989" checksum="CA867DE587976F88" modified="2022-08-03" version="1">MALGEQRARVSARPPPTSSLHDIDDLYDTNGFDDDEDNNNAKSEAAAAVHPLASKGAQPAKQPAKTSAGTKTGSKLEFDVWVARKDKYERVAKALAQLNNERASNDDAWLDVAVSLAATDVVLKTGRTERCDCPGICRDPAHAVTKQRTRCACPARKCSLCKRCVITTPGEITDKMINALAPYKLEPSQSMLALAERIVATGDGKPLKPGQPKITTSVLRMASAVLAQCSVLTNPDGTRLQRPCSCPVRSLGDLWVKWTTKYHTFSRVPLTEAETKQFSNGTRQMMEFDEEAKLYYMTLKWHQAAKPQKGDTAKIAARRALTPDQKQQNAFFLSLCKKNWKSAQITVVKHLQEKMGRFFMLPEEKRTRLPEEYELQVLTALGVKRMLQWVEQDQEALDNAKKDEQKEKADGGVVAHNAWVKRKDRLRIRMPESTTETSSKPTKSAKKQPPRMDFSSGKGVVRPKTVKFPSSTVEIMKNSGLKYVHAMNEGFQGRGGDLEKCKQQLVTKGHILKANFNTKGDDDDDNAPFSKDRYHFERQNNPAIVKKREVVKQRETQRQERYTAWLAHKALKDKAFQYLAHLPTPKRQKEEAKEGEDGPSESDAQVRWIEVGKALKAVDRGLLEAWVRWSDGFVSAPRCRMLWEGFTPVACDVHCSSSAIRDVFLKLLHRTGVNYKQAFLAHCDKKHKKALALGLDDIPDEMTDQEKMERFESLDKREFARLLQDLGIVLQPEELQRVLEYFDQDGNQLVSMKEFLDVVGDKRRRHGDTDLLLQNVCLWETVCHECGMLNAFQLVIGSTKPGEHRMRAELPGHVKRRQTTRCQPECDMHELKQTAPKTCPFATWNDEKATPFLKKLELWSAEHREQHVLQKLVTDGQPPDAPVLYREEDDDPDSEHDPTTTLCLRWQPPPVRGNNGAAFYMLETIGAEGTSSFRLNEYREIYRDPKDYKDNNGQPRYQYVVTGLTPNTKYGFRLRALNGFGAGPYTFAYFITAPATPPAPMVLKVTANSIELMWESSSYFRRQLKELRRVFDEADTDGNGVISRDEFMEELERRKPRLLVFLQKTQAATNGGLSIFDAIETEDNEAISWDEFVRFFQDSWDEINDLETSRSSVKTQASRKPTPEVNNKPTGCRYILKQCTNEARGEYVEIYRGQQPRFTVHGLASASTYQFRVQAVNEEDRFSLHSEPTVVNTLLPTPAPPNLVEMACTSTSVKLKWPTTNARPCLSYEAIQARSKLTTVRKGASNNDDVTRILKEWAQETSIDDGSVDFRAKFDRYDVDKSEFIDLPEFKTLLEELGVPATQERLAAYLEEFDTDNDGKISFDEFKRWWTKTDVQYVLKRDAGATVNDTAASQAMRIVCYRGKDTSVSVSGLAPNTVYTFRLRVVSSHASSPLSDALDVCTPPQAPSCAGMIVVLASRAQICWHPGQNGASRYIVECKGVETLPSSDTATSKRVNGSDWKRVYEGSDTLTTLGELSPNTVYRLRVFAVNSMGLMSEQSTVTQFCTLSKEEERRRGVANLRPSAAADHFTIECCDEGDVVAGDTILFSERLVQTDSGKILAESEVSRSTSSSDSKLATSSVYSTTSYRSADGDNEPIGERTVAARVVGIKRHEKIGNVVNMIVVWSTVQLYEDSKKPSQQVRTTRVNSGSVHTTSHALAMRSNTGALATDLKIARRERSLYRYDVFRREWQDERARSPQTWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ14</accession>
    <name>A0A8K1FJ14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008237</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ14"/>
    <dbReference type="OrthoDB" id="155724at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59887" checksum="9BC7B5224AE87C6B" modified="2022-08-03" version="1">MQIVLPKFDVDLSNANGTTLAAGGALALGLILASHHLLQGDSKNGIKPRKIHRPDSTQPILGNVADVSQSHRYHTWMMEQSLKFKNEPWLWSVPGSSILMVCTPEAFEEMTITQQDVFIKGKFQNDRIEHFLGRGLVASDGERWHRQRKAGVKFFSSRTLRAFMTQAMKKNMGRLDEVMQKSMQTGEQVNLLKLFHDFTMQTFMEMGLGVELDWIGRKEQHPFELAVDLGTMIVNRRFRIPEFVWKLERWLNIGEEKVLAGYLDTMYTFMNRVVQESLDRVNEKKSKPDSGSKEEIKSVVELFVEQSADEEGLRPDDLVEFLMTFVLAARDTTALTLSWLFYELGHNPQVEKKLREELAEKLNIDKDTYLTTEHARELTYLEATIKEALRYYPAAPFTMRQATKDTFLCGDIFVKKGQVIGLSAYVMNRNPDVWGPDANEFKPERWIDPETGNIINMPAHKFFTFGAGPRACVGMSLAMMELRVIIANLIHKYRFDVDPSNDGSYFAAIALNMQNPLFANVHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJZ6</accession>
    <name>A0A8K1FJZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJZ6"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437814" description="Expansin-like EG45 domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="28952" checksum="FB6685BA0102D3D3" modified="2022-08-03" version="1">MKMVHLSRFVSAVFGFGIAILASTTAAENATTVTAVATLYKVQEPAEGLCRLQDADQTSDNFKYYASVSAKTINDGCARCVEVHRDGSLSVTAYVLDVCKNCKSSEIKLSEEALSQLEFDPESEIRGRVTYKYVSCPTSFASGNVKACLMEGASNTYIPMQFSNTQKVITKVIINGQVATPSNDAFFYSVIAPEADATQSEWYEDIKVTLTWDDGETQSGSFAFSSSDGCATSASQFNTKGENSASGHAVYSAALIMISGCLMMIIDMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK57</accession>
    <name>A0A8K1FK57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK57"/>
    <dbReference type="OrthoDB" id="105025at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="47553" checksum="5EC76741F464B0CA" modified="2022-08-03" version="1">MPRRTIRSSSIPTLSLTPDEVHKVEDVATALLNQTLQIESEFFANDGEVDEQHWKQLKSQGNFSIFKERNLEDKAATTAGTRPDTIDCDDIVFSSKRAQVPMIVATGEVDGSVDDAVFGFAGGDIPAWRTRTIYIGDQFTDAKIVATIHKPTVEEPLNYFCIKWFVHEFPVILNAFVNPRDFLQAEAAGVKVDEQGERFGYYMLHEFEHPTIAKLDPYGVFRGSISLVFIMRQVGPGRIHIFSRGYVDPRGDLSTSYTALLTAKGMCTVPQTVNASYYKKMVWLMAQQDREHNDKDPRDRASSMELSQADACAACAKSPGFLKSKFEACRLCQERFCSRCIIEQSLVLDVSGTEAIKRTLPFCLACILKAKQTPPRAVAVDAVKQAHGCKESTFSHYTVSDASTGDLYTLSVRSFNSDEMSERSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLP3</accession>
    <name>A0A8K1FLP3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLP3"/>
    <dbReference type="OrthoDB" id="126245at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF155">
        <property type="entry name" value="DEUBIQUITINASE MYSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="40"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="43"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="209" mass="24211" checksum="0A44EAA9AF2F36A3" modified="2022-08-03" version="1">MTISSRVQRTLFTSSEVIRLPPTVLQQYEERQFKADKRHQPLRRTNIWTREEHERFLQGLEQFPQGPWKQIAELVGTKTTRQTMTHAQKYRQKIERRQRALEHPQTRKRSRAASTATRRAPVLPTHVPTNIDLPLVRVPSVLRSQLPALDPPVNNDELPKLELCEADLADLPMIDLGSPHDITQIFDASVVDPEFDELIESLGPMPVYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLS0</accession>
    <name>A0A8K1FLS0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLS0"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="58208" checksum="32D4FD92BCB482F0" modified="2022-08-03" version="1">MDLEASSPPRARPQRKLNLTLDLDYVNSDEELTAVEETSGWSVGFAVTYGFFFFVGASCVAMWSSITLCLDFFTQKYPDDRVGFVFPVVNMSTLLVISLFMVLVGRQLPLEARVHGSIGLYLAFMVVLPLVNILPVHCPAAYALTIIALVGSTISSSILQSTVYGLAGIFGPLFIQALDGGKGFCAILLFLVRLGLKWYFELPASDSIGSVADPEEVALRLYYAKISMGVFFAVSFLIVAINWVLYAAMKCTQYAQPMLHEYTIVQHETPVAGPVFSPTATPLTSSPRKTFMFPSAVSERSPMVTHRSEMSERSPLLGRRSEADSEATTVERIGRNNSMARSTEADTDFDDMEAPETSSMVLTVFRTAAIPFFTLFLSYFVCLSCFPGLISAIPSTTLDLADWFPIVLVGCYNLGDLVGKNLPIRVMYFDVTTLHLPWCFQLAFLPFFLAALVRPFSDVLVIVAVVLLGLTTGYVATSAMILAPSVCSEYQKEVAGMIASLCAIIGLCAGSYNGLALETLIQLWQDWYVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM12</accession>
    <name>A0A8K1FM12_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM12"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000025">
        <property type="entry name" value="CorA Metal Ion Transporter (MIT) Family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="521" mass="58020" checksum="CA8F8834FAFE29D7" modified="2022-08-03" version="1">MSEHQPPPPPLSSTSSTANTSRTNSANDVPLLRTQLASNAASSSAPGSREASGDLTMRLDSGEPRYRLPELAEAMKQTVSYGGCEVSPIAAYRRIDLPDEPEEPKTSQRSSRSSKTSTSSKKYNCQFDGGGGRTSARGNTLILRFDANGAVSFQEMSRMDVLRMTQEAARPKRHDSFASVDTQGDEEDQSQEELRPARTVMLGGTMGRRGSRRISEPRVMDCAKIVDVQGVHARDIRKLDNMFAVSNEPSIIVRKQAIIMNADPLRAVIMRNVCLVFVPDGADSLLSNLREKFLEHAHPEATEQPFELSALEALLATICRHFEHEYEKTAPVVSKALDRLAHGKIATAELETLRSFKNSMNEFESQVNGVRRALMDILDNEEDLRLLHLSKLYDEPSLLTDLYSFDSEDVEVLIENYLQDIYSTRTKANLMQHRIQNTESLVMLKLDSMRNYLLGVELIFTLVAISISVGTYITGAFGMNLNSHLQEEEGWFWGVVIFTLIVFITSTVTGVLFFRKKGVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM41</accession>
    <name>A0A8K1FM41_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mannosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011352</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM41"/>
    <dbReference type="OrthoDB" id="497541at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF2">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE ALG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW64472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="586" mass="65990" checksum="9E5030F38891EA22" modified="2022-08-03" version="1">MTKKLSKTQPRASMATKDTEERHLWTPTLETAVSLLLVPRVISSLLNPIADCDETFNYWEPLHYLMYGFGFQTWEYSPLYALRSYLYLLVHLVVVKLASWGFSFSLVGTTGVVSKVMLFYGLRGALALVCSYCEALFYRACIPHFGRRTARYLLWILLFNAGMFHASTAFLPSTFVMYLIMLFLTAWMERQHFLAIFWGVVAVLCGWPYVGVLFVPFMFDTLHARGVVLSLIAGASIGLVVLTAEIGVNFFYYRKIVLPAWNIVQYNVLSSETDSTLYGVEPWSFYALNLALNFNIAAAMALPSLLVVFLLPRSASAGAGRRLAFLSPLFIWLAIMFAQAHKEERFLFPVYPLLCLGAAITLSSAVASVWGVFGPGSSFGNFTVTVLVYGSLGLYSLLSISRVTSNVVNYSAPIRIYSHLHDHVLPSPTKNVFMASGSATAVTTLCIGKEWYRFPSSFFVPTNATSVRFLKSSFSGQLPKPFEQHENGTSVIPTDMNNQNREEFTRYTPEDDCDYVVDLNLPGQQETKFWESPGKWQLIHSEPFLNADASRSPYRALYVPFLTTKHVQYVKYAVYKQKRDTTPHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMR4</accession>
    <name>A0A8K1FMR4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75419at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051436">
        <property type="entry name" value="Autophagy-related_EPG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058750">
        <property type="entry name" value="TPR_Epg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059030">
        <property type="entry name" value="TPR_Epg5_mid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139:SF4">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26103">
        <property type="entry name" value="TPR_Epg5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26573">
        <property type="entry name" value="TPR_Epg5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epg5-like TPR" evidence="5">
        <location>
            <begin position="1649"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="domain" description="Epg5-like central TPR repeats" evidence="4">
        <location>
            <begin position="2152"/>
            <end position="2225"/>
        </location>
    </feature>
    <feature type="domain" description="Epg5-like central TPR repeats" evidence="4">
        <location>
            <begin position="2412"/>
            <end position="2552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1303"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2076"/>
            <end position="2103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2094"/>
            <end position="2103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3197" mass="356754" checksum="65778675CC5BC7B5" modified="2022-08-03" version="1">MEAVRPKQKRKNKPKASATQALANEEDGAVLSPQARGAADGARVEVKTLVASPSEDEMDELAMERMLAQPSATDEEIEHNENDLFAFLGADGFSSGDGAFASYGASPGESKPDVRHTNGVVVASAPAFDFEPTPMEAVAMGASSSIGGVSAASTSSHSQSAMQSSTIEALPTTVNSPSMLHVPSSSTLTMTAAPSAPNFDDSDDEDLLSSLSISRPPETQEAVEPAQGSVVPEEAPSQLPDTQDSTEPAQSSVMPEQFRPTAPPEPSESPEYRGDSGAITSTVPSAPLEEDDIQEHMPTPQHVEVPSAPEPTEVSDDSRTETSATSSTTRVVKNVSKEEASAAVRSSFAKILKTDSAGRLYPDVVPAVGVTTGLKPANGRLEQVSAPAKQKVFIKLDPYSNFEMNLLKAAASQKRQEAKMHNIEINKGDLYSRLERYLYAEYLLQSASSTMDSRKKEIDTLSQKVWLIETKRLSASKRCGDQIEIEEVLEFQTAKFDASQLDKLKEHLEKLRQLRTVESCLYTFDRALSYFHVEQYLNEVTQEPDLVSHLNKMTASGVSRSAEGLGEFETVPAAISFYEPLPGNSKLTSSVDHLKYCIDVLIFFEKQVTVDERGIFGRVPPSFSRGELMWHTTGRSMSSASERRVRCYACGCLNMPMEPSQWCRFCESCGVVLYLPPSSISTKSSEWYTATLRFRQSLQKWITFCLRNLLRLRSLVNMPYVLMHVMYLPRISTEERSWVLRFLQFPKAVVSSTGELKREWSEDLVDHYLAMLHLVFHPEKLRRLAMLVSSEPSSRQKSADQGRMSPEWVLLENPDMLDRCYLSDEDFVAVLNQFPNQFALEQLFNCTLDAKKSFSRALALVVEFTQGLRLFQEFEKFPARVAQLLGDVLSYASLVPAASSSVTRDGNAIVYPTLFDQLFLTALHGLLVADCNRVAWRSIRNFPFAPLSDLAKWDVLALLLFGVHQVPDTAKNHAGWVEFIDRTCIGGPESTKRARSVLYSQIVSDADNAMHLLHAAARLAASTDDKDLVRVATNELFLAGYADIECRRVLGESGERAAGPISTICLAHPWVISELISLLFKYHECAETWIHVFETFPVNRWLPSVADLTNLQEWLLLETSAPRNALARFLLDRINWDFDAKEGKLFTSPYLHRQVALVVAEALVSYHARRRNEGGEKARSSTGSVVSPPKFKVLTKSLRRVLRLEPTVDFEQWCWRLMLKLKFYSPLTHHPFIDLVDLKQDRSREALLLRRWFPGAVSTFSLGGKTVPFFGSLDQLLSLIYKNGVNVSSMDLELRAALAGVPNSGSPIQEEEDGAAKAEKESDDPELESTVAVISTCEAEPIVAYLVCQMSTFLFTDRIDRWEPLLILLKNNLFNASVKVLESVLPLVAKLERAKLASTLPEASQSDEAVVGKVDHDLSACMAVIESLSTDQLLQLVQAMRRHSYISMDELHLLSDLLQKGYIVLQVPFWFEHPALRHLVDVVLRCSMQEAFAASSSSGGRKQLQVRLVSILQQSFVDICQDMKHEIDLGEESNPGQIPELPPAISFLPADQSSPALASIFGGGSDAAQFVGGCSVLSFWALLTETRQELPLFMALGELLVRFEPTSMKKVEKIKKTEGKMRAELMAVGFTTASKPYSSVLFAHTTYESLSQYRIYRWAEYCLMLPEDDELQILYWQVLFALYYACTGGTKVFGHWFFAREESKYPKRIQLRKNLQLKLRSMTTYCSNQAQLVLTNTGSAGGMTSEGKDRRYHHYVQLSHIYTAMDTWLEEQDPNKWLKDEELSTLPRHFEVGRLRDVLNLSDCLLNTPPGDFRWSGLPLWTELCGFEFAAPLRVIQPAGEDTTDEPPPPSTEHLHEEDFAFIEDSKDFRRHSSLGSSADHGRTSDPLALTAEYSGPSSLTLLPHVTVEIRAESCVITPSIPLNKQGLKTLAMKFSENLSILVGLDAEILDHISKLYSSKPRTITESKPCIEGSNCRSPAAFRFEFTEWTIDNHLSDTIESTLSQAARYEMKSMSAGAIVPMSNLDYGDHTQHSGLLSNGVDEFLRLDADGLMLSMQILLIDQLVQVLDHEVEKTKRRTEVASASTTEEDESEDKQVQDTEKEAARLHEKGLEWFRQLTELDTKLSRMVPPLREVLWRSIKQLGITFVCVDERETYNLLQLMLDDPSRIMLLSECFSPASAPSRFVEMFSSLMSASSASKLSSEDKLTLLRRFDFKAWLQTKAPHTPTKFDRDTILCIVLGDIGKNFEKDGSLSGGASSRRQDTNEVLQVYAQIVHMICSAHLGDHLEKVLHALVGVQDDYRFNTVKAGAQAGENEDGDPAGSLPKPLAAAIWESVIKIPPSIWQQIPFVQVEACISFMSQHMSSLRMQASTVTGNENAPSRFPLGMWQRSGVLKHYLDLFTLLWKSSPESQKWPLILTFFEPLLSTLYMPATTMDSSSICGPWSEQDSLSTGTTLCSCFVAVCTEYLKTKGAADEGASSAIDPSVQKSQPATATVKLDRIWNFYVTTLIANSPVYVCKSFHQFLTRLGWEHWCLRLEIVQQMRELVQTEKQQLALSSSCPDMNSSSTSLSTYPYVSWIVRDILCRMTWKATEEWLSGQNEAIRSVFTMDLVKLCIELILDYPHFQSQQSKPQRGRSGGSSANVLPPYFVNFIKQQPAVWMKWKMNSSELDSLLGFAVDAVLEPLRDLSGGDNSSRVFSTGVSPAVMQDAFTRLQLILRVMNQVTSVHHKAMTRKENLNRSNRFLRSVFQIFDTGYSSSVGDFGDKNQAGWQLVLFGATCTVLYEKLDEIVQACRNGSGSPGTGGGGESVSEEDLLDTVIEVQRLYNLRLVEPFFKAEQADGGSKTSLNWGKCGNVIFVEVDSLIRDFTSSQKSGMRVPVPIDSLSDDDMAMKPSSSPVDAIGNPLGRLLWSFMGFRGGELSSLAACGRAIASVQVMSLVAEKSIEKWIIEERRGTWDDLVARLRVPELSEDEFESACLQQGNLLTLQVLFLQQLRKAPAMTEAFAMGMLSKLMSWMHKMPLISSTNTLTEMKILFFAAEVTNFVFRILADVLPAAHKKQALRDLCNLMLQLGNARRQHGIMKAIGIGGSLKYNVEFHVCSLTIGIFLRLQTRNGAPLRVDERIPYKLTRTTEKHLKSLEQLLTSKNCFQLQKRMEWMLDFLKSPSRSLADLDEFVVSLFSRIYPSHPWLLAKCISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMU2</accession>
    <name>A0A8K1FMU2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMU2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="225" mass="24720" checksum="1E1A1B38114FED24" modified="2022-08-03" version="1">MGANAYMDWVLKKESKKRKPRLSLIAEEGQEGAEASRVERNATVPSAADMEAYFKGLMERDTKASLTKAGVESKDGVAKLEKERVGERPNKRRRDESTATTTTATMVSRASTDTSTAAFSSRLIQLPHKEPHKETKKRGASVANLPDRSTIPTTATSEPTMATKKHRTASRASALDSALVSLPERVETQPQKATTAATSNRPRARGPVIDEARYWQDVDRFSFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNA9</accession>
    <name>A0A8K1FNA9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_011348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNA9"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035464753" evidence="3">
        <location>
            <begin position="21"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="578" mass="58294" checksum="6816E4D8B699BFF3" modified="2022-08-03" version="1">MKLFKGVVLAAVFCAAHVSALTFEQYKPGQPGVVRPPTGEITDDVTPAPTDVKGLPEIPNAEPMKPTEPAELTKTPSAGSSSEDCEFPIAGGSKKPTPGKPSTGNDDDDCEFPIAGGSKKPTPGKPSTGNGDDDCEFPIAGGGGKPSKGGDDDCEFPIAGGGGKPSKGGDDDCEFPIAGGGGKPTGKPSTGKPTGKPATGKPTSKPTSTPATGGDNEITLPTETPSSGNDEYGDEYTPEAGKDSEYNQSPSPTTPSKGNPAPAPSPSKGGLTPSKGEPAPAPSKGGSTPSKGEPAPAPSKGGSTPSKGNPAPAPPSPSKGGSTPSKGSPAPVTGGDDDDCEFPIKKDDDDCEFPIKKDDDDCEFPIKKDGSKPTGDDDCEFPIKKDGSKPTGDDDCEFPIKKDDSKAPSPSKGAKPVPSKGSSPSPSKGAKPAPSKSGNDNDVPLPSDGDDEYSPSETPATPVPTGSTKLTPSPVLTPVTTDERENDAGTDVSQRNKVIKANTLSSPEGFEVNAVSLNSEDEGSDESGSVVVVPLVAGGCAVLVLGAMAVIYKKRRNAKKNKSSQGAIFTLDQNASGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNQ1</accession>
    <name>A0A8K1FNQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001787</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNQ1"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF17">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="272"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="10">
        <location>
            <begin position="483"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="683" mass="74249" checksum="A3F5260BB57E88F1" modified="2022-08-03" version="1">MTRSSNGAGPTELTPLIRQRSSTTDGYAASSITSSSPSSPANGTGNGWRSPRAQYSSPTREHLPHVLLQASREDEVRSSTSSSSRSHRGNLSAMLDEAADESVASVAAVNGLELEDSDGDEDDANAEDVAYFASPTKILCTACMKGDLMQAKTAVEMVVKKVEARCQAADDGDVPRRRLFSDAVVHLLTTHDARHQMNALHLAVLYDHPLIVEYLVATAKRHCASAEAFQEVLDNRCGDSKHRATSLMLCTSVAVAMILIDNGASLRARNSSGMSALHYASSTGNAGIVSLLIERGAEVNEADSRGATALHWAVFEGFQYTAMLLVGLGADQKIRDSEQQTALMIASALGDSFLAKQLVIEGAPLKFTDKHGRTAVDVARQGGHFETVSALKAGASDRFITSISRKGGAVIFFWSAVVLAETLSLWYAVPSLPNAHFWSTVSLVICAVTCVLYTYVWLKDPGYVPKSTQPAYELLAVECSSVPCPTCVTLKPLRSKHCSSCRRCVYRFDHHCPWINNCIGIGNHRGFLFFLASLSIFCAFIATVSMMILCGNLPLQTPPATSDEGQPLWKHIFSHSAPSSASTSPLVLRIVHFTLVFGAMLFGIPTTILIGIQLRNIKNNLTTNEVFNKDKYPYLKTPMDEFHNPYDQGCWRNYVEVCAQENTERVSEDGRRNTSIVDPNSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNX7</accession>
    <name>A0A8K1FNX7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNX7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW69871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="431" mass="48501" checksum="0DA5E90911AF848B" modified="2022-08-03" version="1">MDEVEVELECAVYGEGSVFPVKIARDAKVSALQKAIFDDQRYHERFSFPPSALTLYLAKKNGAWLADDDNLDALLGGDVDKQYMKMRPSWILSEDYLGVNFHPERKQIQVLVELPEAAAGEKSETAQMMKEIHEHVVRPKRKRYVHSEMSSTKGNALLQDLNIRVKPADSVSFTTEDPTPVEAFTWESVCNEHGQLIVLTEEQQRERYRRYVEDNIGDVLAEKKLCVLGVEKGKNILTATVPGHDIDLVGRTDMLVLSDVAKREPDHLEWLPEVKMLIEVKRNVKGGSMFQALSELIALDVLVDDPVMALLTDLTGRWQFFWVSEKSNNRVIIRTVIISNPSAAFAVIRTLLAQSPNGDADITLPYFEGPVKRRKLAQLLPSIGEGGESSGIREAIERYYDIASVLGPDIDMARSVAHQIVRTIPTFSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNZ6</accession>
    <name>A0A8K1FNZ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4 10">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009295</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4 10"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNZ6"/>
    <dbReference type="OrthoDB" id="447729at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000001">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000003">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006438">
        <property type="entry name" value="HAD-SF_TIGR01548"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01548">
        <property type="entry name" value="HAD-SF-IA-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002111">
        <property type="entry name" value="PRK00951.2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002114">
        <property type="entry name" value="PRK00951.2-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="451" mass="48599" checksum="63DB52518EB389F7" modified="2022-08-03" version="1">MVQLTRPLQALLWDMDGVLAEVSMSYRKAIVETAKHFGAVVTFEDIEKAKLAGNANNDWQLTHRLIASTLSDAAPLPTLEQVTQVFEDLYQGVEGRPGLCLLETLLVPKGLLQELNRRLPKGMAIVTGRPRKDCIKFLAAHGLEEFFPVHVCMEDCPPKPSPEPVQLALQKLGVAADEVAMIGDTVDDIIAGVTAGVLGFGVLTPQVHAKSILEQKAPVLEKALEQAGASIVLTPGLGELLDIIPLPATSPSTWDSHPRSAVISRVTKETSIDVKLNLDGTGKSKVSSGIGFLDHMLTALSKHSRFDLELDCKGDTWIDDHHTTEDCALTLGEAFDKALGNRAGIARYGSAYAPLDEALSRAVIDISSRAHSEVNLELVRPMVGQLSSEMITHFFESFASAARLTLHVDVLRGRNDHHRAEASFKALAIALRNAVKADETAGVPSTKGVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPZ0</accession>
    <name>A0A8K1FPZ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_001020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPZ0"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="73" mass="8580" checksum="3E454958D96803EC" modified="2022-08-03" version="1">MIVPVRCFTCGKVLANKWETYLGLLRADYTERDALDELSLKRYCCRRMMLTHVDLIEKLLHYNTGAIERGEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQL6</accession>
    <name>A0A8K1FQL6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQL6"/>
    <dbReference type="OrthoDB" id="161167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="99"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="25921" checksum="822A02BA65510DB1" modified="2022-08-03" version="1">MSVYKAAAYQSTQSESRLPYEATPLTGGVPMIGVGSIVGNLADLMYLATTLTDSDMLIQSSYDEDECVDGQLLCTLEHGTTEDPFHRHTLKRRVKQAPGVASAVVRCRDMVFLDCIGQIQLPNGEHVGYVLYRTVEIPECNEINGIVRADGTACYLLRPQGPNSMEVFMHSQIDARGNSMDAVTAVSAANALIAIWKMPWGGQNKKLAWMLKQAGAKRSQDGAASVERMTMNQCPVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQR1</accession>
    <name>A0A8K1FQR1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQR1"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052718">
        <property type="entry name" value="NmrA-type_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129:SF1">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47129">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="302" mass="32058" checksum="FDD82C45BAB4CF04" modified="2022-08-03" version="1">MPATIVPGRLLLTGASGKLGLVTLHHLIHTLQADPQQIVAGTRSVDSDALKTFKDQGVVVRFFDANDATSVASAAEGVERALLISNRESDDGTSHAQAIRELVKAGVQHIVYTSLQAADVSLAAIAPIHRATEEFLKQSGVPSYTILRNSMYFENVFPSLTVVSKTGGQWFTAAGDGKLAGVSRDDTGRAAAYALATDRTESATLDITGPEALTIEEITSNISDVITKPIEVVHLSREELAGRLVQVLSLPPPVGYIFASLDATTAAGVASQVTSDYKLLTGVDPVSHREWAKSNQHILTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C1Z2</accession>
    <name>A0A8K1C1Z2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000158">
        <property type="protein sequence ID" value="TMW54934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C1Z2"/>
    <dbReference type="OrthoDB" id="111500at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49028" checksum="B1F406CBA003F334" modified="2022-08-03" version="1">MPDPTAIPSFLWQQLPLLYNMIAPNRLSGHSMSKPSGPLSASFLQSFAEFFASRKVTIELVFMTICWVKSVSALQGDAGLSRNVSRTIYHRWKLQDRLEKLISKGDAVPTMQKSMKKMLDDLKDAEKGDMVIRANPVLAGFVELDLHLLYLHVGNESVFPTPHFRGFCHLLMGMLRDSKGPLDNGDAGILKTMVNRNPALLGISASTTGARASDLDILLHHAAAGPARDKRTVEWMIQCGALYLQPTHCRNPPEPGTLDRGVVRKQLCNHLAVHSAAAAGLEDVMRLLLEADHLRDLNTRTFHTKESLAHLTVKNGHRGVYELLERLGADVRHPDAKGKYVYDLTSDASWKESIRALAEKQRRDYDSKGERKYVRANVTLAKLLSKLGKQREDAKSASPSNGKPAQTAPPPAPTTTQSENSTTKSVKKKKKKKGKEEASGHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C213</accession>
    <name>A0A8K1C213_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_014768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C213"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035450592" evidence="2">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW54997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="148" mass="14316" checksum="B2041876131B7F14" modified="2022-08-03" version="1">MVKASLSLAVVALGVVSFTAVPRLAVAAPMHSEDANDLDENPLGSVVAAVAEAPAAGGWVYSGPARPDSAVFTDWCNTNCAAGFCPADMCKPAGGAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPAPTTKQPVIPPSDLDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C296</accession>
    <name>A0A8K1C296_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_013875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C296"/>
    <dbReference type="OrthoDB" id="1378at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08063">
        <property type="entry name" value="MPN_CSN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033859">
        <property type="entry name" value="MPN_CSN6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW55113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="36983" checksum="C22F908ADE2ADF10" modified="2022-08-03" version="1">MEDTEMKQEEEVFDTQHSGPGGEGAGAGGNGGAERQIQVHPLVVMNIADHYTRQKRNFQYEHPGQAEATMPQVIGGLFGIQNGLDVAVYDSFEMKYDVVKGEVQIDKEFLTSRIEQFAQVFPGFELLGWYTVGSKAQQSDLAIHRAVMEFNESPLFMLLDPTPQGPNTKKKLPISLYESELHVLNGAPTMIFVKTQYKIETSETEGISVDHISKIAPMADSSKSSLHPYLGNVRDAIKMLHRQSDVIVAFLQAVKRGEVQADHNLLRHISSLANQLPALSSQQFDAAFLQEYNDTLLVSYLATLTKGATNANTVIERFALTQDRQSSRGNYMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2J7</accession>
    <name>A0A8K1C2J7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_013169</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000289">
        <property type="entry name" value="ABC transporter G family member 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001374">
        <property type="entry name" value="Pleiotropic drug resistance protein ABC superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="610"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1102"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1131"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1176"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1212"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1240"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1328"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="82"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="765"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW55278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1358" mass="153208" checksum="026838C61CF51E7E" modified="2022-08-03" version="1">MTDKKGLLHDEVADDVPQVYRSLNFKSLQDPYSHRDDDMISRYSTIRADNLDNMLSGGLERFYKKYNHLSHKINLQLPTPEVRFENMSFSVDVPVAEKASSQYSVGSYLKKVFTPWDRPPIQTKQVLHPMSGVIKPGSMTLILANPGAGKSTFLKAMAGKLKNTSKTKFGGEVTYSGLRADQIDLIKLAGLVDQRDNHVATLTVRETFKFADLCMNGRPEDQPEEMRDIAALRTELFIHILGLTNCSDTVVGDALLRGVSGGERKRVTVGEMLVGGQSLFLCDEISTGLDSAATFDIISSLRTWCKTLGGSSVVALLQPTPEVVEQFDDILMVNEGHLIYHGPRTEILPYFQERGFTCPPRTDPADFLIEVTSGRGRKYANGNVEISKLPITPEDFNNLFCQSSIYKKTHEHLSRGFNEANFEKPEDFKKAKAVGNLARSKEKSEFGLDFFRSTMLLLSRQKTIWLRDRPLLWGKLFEALIVGVVLGVIFFECDPKYYLRMMFFSIAVFQRQAWQQIAIAFQLRQVFYKQRSRNFFRTSSYAIAESIVQVPVNLSVAFILGTFFYFMSGLTRSFDKYIVYLLILVAFQHAVGAYMTLLSSVSPSITIGQALAGVSVSFFLLFSGNIILADLIPDYWIWMYWFNPVSWALRSVMLSEFHADRYSDNERDSFLDSFSISQGFGYMWFGIIVLLAYYFLFTSLNALALHFIRYERHLGVSGKATKTDGDEEEAVYVEVSTPTAGAVNGAEAVTARAKGGGLPFTPANLCIKDLEYYVTLPSGEEKQLLNGITAHFEPGRLTALMGSTGAGKTTLMDVIAGRKTGGRTLGDIIINGEPKDPDNFSRITAYCEQMDIHSEAATIYEALVFSANLRLPPNFTYEERMNLVNETLELLELTMISNELIMNLSVEQKKRVTIGVEVVSNPSILFLDEPTSGLDARAAQIVMRGVQAIARTGRTVLCTIHQPSISIFELFDALLLLQRGGYTAYFGDLGKDSVVMLEYFASIPGTEEIRPQYNPATYMLDVIGAGIGRSVKDYSVEYANSELNKQNRERTLKLIEPSPEFIPFSTLKFDSIATPFSNQLKELAKKQQLTYWRNPQYNFMRIFLFPLFAVIFGTTFYQLEYDSIKKINSHIGLIYNSMDFIGVLNLMMVLEISCAERAVFYRERMSNYYGPLSYSLSLFFAELPYLTAVGFLFVVIEYWLVGWSSAAGDFFFFWWIFYLYTATCTFVGQWMAVLTPNAKVANVAVGALSCLFNLFAGYLLPLPQMKGWYKWIRYIMPSSYSLSALVGVQLGECKDGNIACQELPDAAGNLVQVEKFVRDEYDFRPDSMYSFMAGLIVFWIVIQLFIYLTLKYVSHLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3K1</accession>
    <name>A0A8K1C3K1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3K1"/>
    <dbReference type="OrthoDB" id="425082at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032727">
        <property type="entry name" value="CLAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14769">
        <property type="entry name" value="CLAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="146" mass="17223" checksum="70F273085FA38D2F" modified="2022-08-03" version="1">MADAITWKYVSKEQVDRLADHHAMDDCRRELAQVFKIDLEDKKQCFLLDFHVHNYSYPSQKSSCKGRTQVDMTEFLDLCYVTFCRQAHLHPEQISVLLGILQLLMEKDFADDSQTTLEQSYQAFQKLLLDHSVERSPKRRVFRAFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3Z6</accession>
    <name>A0A8K1C3Z6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acetyl-coenzyme A transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008727</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3Z6"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW56079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="59046" checksum="F4ABDD237B638B32" modified="2022-08-03" version="1">MAPSKSHEASERKLRQRKGGAKASAAADVQATLKDTQKPSQDEDEAHDWSSMLLLLLLYTLQGIPMGLSASIPFILQEKVGYADQATFSLVSWPFSLKLLWAPFVDSIYSPSFGRRKSWLIPVQFICAGLMIGGSFFISELLGEGDGQKPHVIYLTIFFFVLYFMMATQDIAVDGWALTMLSEKNVGHASTCNTVGQTLGYFVAYVGFLALHDPATCNSYFRSTPQPDGMITLAGFMNFWGWVMFVTTVAVGIFKKEKEDTEEQLSIAETYKQMYSVLRLPSVISLSIILLTSKIGFAAAESVASLKLVEYGLKKEKLALLTPILVPLGIVIPVFLGRRIKPDKPLDLYLLGYPFRLVIGFLYAAIIYITPSVMAHDEDMHFYYYAFILFCGALHEVAANLMYVPQMAFSARISDPAIGGTYMTFLNTVSNLGSKWPSSLSLALVDYLTTRECLGGSKHDEILAIGSHTCSNIDERTACTNAGGECLIVRDGFFIEVAVCGVIGVFWLAFYYRRIKYLQNLKIDKWRVSGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C450</accession>
    <name>A0A8K1C450_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C450"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23408" checksum="069EBEE265E5B26F" modified="2022-08-03" version="1">METPSATVSIDASDVTTTKNDLVGKLGWLDAMWGGVLISPEAIIVLMEPIDLDKPSSLEGKRDPSRTRYRTTKSLFPSTQAEQKRKRQARNRINVRRLYYRNKTRLIALRQEARGLEAVLRSLEASLPRRRRLEALAALLTETATLEREHGRLVSTLDQYRRFHAHLPVTVAQHTATPYAAPSEPANTRVDKCASESEIALGDYPWCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C452</accession>
    <name>A0A8K1C452_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C452"/>
    <dbReference type="OrthoDB" id="1306014at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="298" mass="31443" checksum="68E5AD0E1319475E" modified="2022-08-03" version="1">MGKKKRREEVVATQRRIYCYYCDRAFDDEKILIQHQKARHFKCHICHKKLSTASGMVIHMVQVHKENITTVPNAKPGKDSVDLEIYGMEGVPGEPSAYADPSKRPRLDGPGGLPMGFPSGMPGGFPPRPPPPPPHLQVPGMMHMRPPPPGPPPRPPFAGAPVAPPHLSAPGGFPPHIAAAPVQPPFGVPPPWAAGGAPGIPVPGVPPPGVIPPGMPGMPVPSAPHAAAPGFPPTTVPGYPYPGAPAAIPSATQGPPSELATELAKPDGMVFYDEQVSMEEKRALRPKYGYKPLATSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4U6</accession>
    <name>A0A8K1C4U6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4U6"/>
    <dbReference type="OrthoDB" id="74314at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051942">
        <property type="entry name" value="DENN_domain_containing_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15288">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15288:SF0">
        <property type="entry name" value="UDENN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="522"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="578"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="936" mass="104292" checksum="4415465F70689822" modified="2022-08-03" version="1">MTGGRCDGRSPCVWRAQYEQAQDEVLLLRYESQKWKEKYLHEKQRRRLLARSLLDAMVMTHEDRGHEGGRHSLTRTRRSSSTFSDKDHIESLLSPTLSSFDFDDDDSSADSDIADDEDTRETIVATKDTAATEAAATKEAVTRHVDFQPSTRGRTTRRQSVRPSRSSTIGSSDVYRVSQANGWRKDARPMPPPPPPTLLYRMLYSKSSSGDLWTTQSHHHKLQSVARSIMFSMQLKKEHVFEHCFVVGLSVGKSEREHAAKSPSGLVGFWKPRVLYQYPQRPGRQLDSSVADFCFPVGVPVTKSKKHQAASLRGAPVSIWSTDAETLQKHVLEPFRTSGYSFQLTGAKGEILHGFCVSILSDVVTVDDGDETGASQPRSPRSDWTKRASCPNGSILRLSEGEESGSFHAKEPPSDKPSASTHLAPICYCFTSKFPFYRLHFSILRMVVENELRVKQQPTRQNENQYEVALTTESSVGIEFAVCRQPNVGRFSGNDGNSNTLTASIATAIQYNESNDTVMLSEESSNAGIHASGDRQAAEARHNQSAALKKSFSSDDVGIYSPTASCVVEKPVVVRILATQSPVFALIQVGDVLEAVDGVSTASLTFDQTLEILKTAPRPLKLRFQRLDTQTTSPISISRDSVTLSPSSVDILHRVRTLKISDPGQWSTVRLPEFSLEYQFPKRLAERWAVGVALRHLVPSSIVKILAHLLLEKQVVIMGENAAMVSAVCTAFMLLLSPFQWQSTYIPQLPSNLLDFLHSPVPFLVGCHALETTEDWTDVCFFDIDANVILAPIADHHIGETSLPHGAELRELFQGASDRYHHLRPASKPWHELSDDEDKIITLTMQESELFLREICGELTPPDVSLVDGKSFYEQVQEQVGLMVRQSHYEEFLEEFSQTQMFCQYCETILKPSTDVTLAPVPQQRMTEGGTSVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5G1</accession>
    <name>A0A8K1C5G1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5G1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421800" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="781"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1145" mass="113626" checksum="A259ED4C5C0D7BA7" modified="2022-08-03" version="1">MKVGFTTLLLSAIAVAALPAATEAYSCDCSVDNSFRQDNKCIEICGQNRDDDVGNDNDDSGDIVQRPQPAPTTVKPTPAPTTAKPTPKPTTGKPTPAPTKGKTPVPSPSKPVDDDDDEPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPAPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVDDDDDEPTPAPSKGKPTPKPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPSKGKPTPKPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVDDDDDEPTPAPSKGKPTPKPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPSKGKPTPKPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPKPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPSKGKPTPKPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPKPSSGKPTPAPSSGKPTPAPSSGKPTPKPSTGKTPVPSPSKPVGDDDDEPTPAPTKGKPTPAPSSAKPGKPTPAPTEPVGNDSDDPTQGKPTPVPASSKPAPVPSSGKPTPAPSTGKPTKPGKPNDAEDKPTPSPSKGKPTKPGKPNDDDDKPTPAPSKGKPGKPDDDDSDDKPGKPHKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPAPSKGKPGKPDDDDSDDKPGKPNKGGDKPTPSPSKAGTLTPSPAMTPAPSKTTPAPTSGKPTPAPTTPAPEDDDETPIQRPSKNLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5I4</accession>
    <name>A0A8K1C5I4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5I4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="110" mass="12287" checksum="AA6480A76C57EE96" modified="2022-08-03" version="1">MSMITLPAAVVSRARDLFVLYSTKSAFKLEEYADVGAVYKRLSEAAQGEEPTEVSETDVKYIISAINVCAQRTPVEVQNYKPIVDLLETLAKSLQPAEEEEEEEETKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5U6</accession>
    <name>A0A8K1C5U6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5U6"/>
    <dbReference type="OrthoDB" id="64941at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="885" mass="100181" checksum="008C5420B79C8398" modified="2022-08-03" version="1">MNEEEYPSPDPATMEKLWQEYNERTKHPTKTVDKETYHRKMHHRYNEMKALRERVASLESELEEVRSERDEARDISRRNSVMVDRSKSKTDEEPSGGSDGLPNTEERGGTSQVHLERSASTLSIPQPATSPRSKQASGISAEELTLREKCFKLERSLALAKETIDRLQAKILSLHNSDQSKIDELRAKLRLEQEASQVLAVQLRETNAAFKTATDELVATQVALDKEREERQVAIEQIQAETNQFITDHKRKELQSRVKSVVRTLGKEALRQKMEALHTRTLMAEHHMRAAQLEVAKLKAEREYQQAELDAILASREIKYHSLAPDDGGIPGILGRSTILYHGTRLLNDQYLLVRMLYEDNRASITKSMIDGTTREPVTDLEDGFSVHVIVYEAFTAQDDYLTFHLRDIQRLVPDCEKYLATFADRRHERYLELAELLFSQCHIGYKNGHLVLTERPSSALEAASRERTEVTIYRGSRFVTVADSDTCILVDLVVNEVYMPSMSQLWWLEIQATAIDTGHESVLKVDHQLLKSCCATFASYRPSESVGSGMVDEYELYGVHAELLESVFNQVQWHPTTASLWIESALTEEQSDESQECAQQPQDPDSNENPPVIPTESRPKSIHKESSDTAQVLDHCSIVGVEGIFYCLRIQELWDGELMLRITMEEPDATIEGYEMVLCESQLVKIAAYLFRSGLCDEDHSRIVKYGLPGSLQGPMARVLKKHLRPLRNEMCGDTSVICSPAKQSMRKKQKISLASLLAEMTQNSDSDDPISTKWVKLPAPCRLLGRPFQEVQIMGGGPSEEAIQAMFNDLQENPTLLTRRERFGCRYETKCDFATVTTYSGFPKAPERILLSVCPLESSAVLIVLTQGSVLEALASLGLRWIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6I0</accession>
    <name>A0A8K1C6I0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_003426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="444540at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051581">
        <property type="entry name" value="Ca-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524">
        <property type="entry name" value="CALCYPHOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34524:SF6">
        <property type="entry name" value="CALCYPHOSINE LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="373"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="655"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="692"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="728"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="996"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1023"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1059"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="922"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="927"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW57501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1477" mass="162381" checksum="846765B5522F6D65" modified="2022-08-03" version="1">MTSVTPRATSLTQWNAVQQQSAETVDVPRLVAAIQGSLRQRGLAAWVTLGQGLERAQQDSQGAGLGRATLKRVLTGNQLQVSEVDTRALLRFLTPQDDARVSADTIKHLLCGPLTGRRLELVQGVFEQLDHQRVGYVSTQDIIAWQDASKHPSVMFGDKTASQVHDELVSSFMALLSATGASTFVNLYQWMTYFQYVSGNAPSDEFFDLILTRVWKATPKTSLRDITEPSATDERRLSGNSTTITPPLSLLQALQDAKHITVPPPAPISTSAALPQRLHRSQSLTMPSQEVVSPRAAHTTAEFLKGAQFAACLVDPTLRQPTNLSPRSKNRGSPRVSMPGVAAAATPAAPILDAGTLSVLNRLRAAIKTRGLRSLVALTRQIRLSDADGDGLLTLAEFKVALRPSSDDATPLSESDLRVLFKYLDRDHRGAIPIHVALDFIREPMNPRRLALVRAAFEALDPLGMRLLEPSDVVQRYDARRHPEVIAGRKTEEQAFQDFIEHFDLEDATQGKISLAQWEQYYHNVGFFVPDDDYFELTIRNTWQLQLQQLTTASPSGNDTGAPGHAPLEARPRIVRGHAAGHDSRQAFAILQPDLGDHHAAILAAERHGISNASPSKTTAAAAASATAYTSAQQSKEIRRIIHQLRTALKDQGVVGFSSLQRAFRLMDEDRNGSISLHEFTRALRECKLHTVTPQDAQTLFHVFDANHDGALDFTEFLLGIREPMNERRMLFVRMAFDILDKDRNGVLEVSDIVDVYDARKHPDVLSGRKTERDVFTEFLESFDIDHLHEGKVSFDEWTRYYQNISASIDDDDYFELMMRNAWHISGGKGWCANSSNRRVLVTHADGSTSVEEVENDIGVRKEDVSRVLAAQMERRGSTGMQKSSFYDVLDHSSRPTAAPTGGLGMVRTKNNSSASIAACLGGGGNANTNNERPSTPTGAPPLSRRRSSSLPNQPGNALPTQPTSAPAGVQAIISRLKIALKAKGAHGFCGLSRKFRILDDDGNGSLNLSEFRKAMRECDLELNDGDLRLLFQYFDRDRSGSIDLNEFLIGVRDPLSERRLGFVREAFKRMDKDGNGLLEPSDIVEAYDASQHPDVMSGRKTPEDVFRDFLETFDVDGIHNGKITWDQWVHYYQNVSASIDDEDYFELMMRNAWHISGGVGWCENTTARRVLVTREDGSEVVKEVKDDLGVKIQDVAARLQAQEANTASKTASIAMSSAFDLTQPPQTGTKKIVSLKDASFGAPLQLMTAGPSVSSGNLSGEIVFYSIRRRLQQKTVSDVVALRQGTIKYIDAKTSTISAGHCAEALSSTLGLTLSEAHCMALIEYMNQLPEAQHNETPGLGSVPAFSIGARLLQTQTQATRITIKRLFACLLGQLSPRCAESVRRIFSSLQAAGKGRVFPIALAKSFQAANHPDVKLGLTTADAVFQDFAANLELSGTSDGSVALEHFETYCVNLRATLGSDEYFALLLRECFVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6M4</accession>
    <name>A0A8K1C6M4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6M4"/>
    <dbReference type="OrthoDB" id="102630at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21502">
        <property type="entry name" value="vWA_BABAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="238" mass="27043" checksum="29C9C4D052FF4642" modified="2022-08-03" version="1">MGSVGTDRMELQQLMRTSSRKPEHLLFCFSGFDARWTNPDVLNDVLELTERIIRIKHQMNPKHKIELSYINLNTLETPVAVTTDPSETRAALDTIKTNLLSLRLESRLRLPAIVPQVVQYFRQNSSSDVFTPRVVLIHVHSNQLEIEPFPEEVEGNAGELLSLAVDCVFLRGQQLNEQAQLAFDNFCSLDFFTSVVSPYFLDVSDSKERLHQAFSLLLSHPAHRLPQEKVETRLASSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6P0</accession>
    <name>A0A8K1C6P0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6P0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47293:SF15">
        <property type="entry name" value="JACALIN-RELATED LECTIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47293">
        <property type="entry name" value="JACALIN-RELATED LECTIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="26"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="344" mass="38856" checksum="0AEE093F5494E3BF" modified="2022-08-03" version="1">MLDSQKRLVLHPTATQPDLRLYPYFSTLLGAGDGAEGANDWSSFGFDWQSTLWNIGAIHIVADTEYVRSLTQVASEYTEDSLMSEQFYVHSGQNIFQLVQDEKIMKVAVWFDDKGVRALQIHTNMRVSQPYGSVQGTHCVFEAKEGYHIHSLCGKHDEEHIRKVGVLFYPIRDDPPPTPRVSGQWMHTTAIAVGERPAIEKDMEEINRDVRALVLQCAFVVSYIWVISQQQYEDFIVLSDRITLSPDEQWVVLAEGEKITSVTTVPSAKRIESIRFTTTHRQTPWFGTYSMGTPITLATPDAYIYGFHGTYTDDPDAFTSLGVVTFQPEANDTDTRNTDASSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6R1</accession>
    <name>A0A8K1C6R1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6R1"/>
    <dbReference type="OrthoDB" id="162741at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035446693" evidence="4">
        <location>
            <begin position="20"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="244" mass="26472" checksum="2ABD8918BA3C97E5" modified="2022-08-03" version="1">MKFAVFASSAALVASTVNAHGYMSVPKADFPNGIDTSYLKTIDADNHAVFKGNKWNDSPDNNVAMFTKVFKSQSTYKTLKDLIDSEKVDACGKNVLNAQAIDVSKENSVKWGNDQEQKGFITSHSGPCEVWIDNTKVAQADNCVKAYPTYPASIPVDYSACKGECTLTFYWLALHEPKWQIYKNCAKIKNGSGGGATAPTTAPTTPSKAPTTPTNPQPTNAPQPTSTPAPTKKNCSRRRALRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7H4</accession>
    <name>A0A8K1C7H4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7H4"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="402"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="862" mass="95861" checksum="6E33EF2687B9FD62" modified="2022-08-03" version="1">MTSIDAAFATHVALDDGVLATSAPLEMTQLQRVVVLVEAGLAAYPDTAQRVRELHDRLVTQRVIGAADAVAGMLEILHAHDQARAFFKESIVKVLTGERMTWATPAFSGGLGRVEDPPTVTEEPSLDTTPTKQSDQSPSRESSESPASDHEATEKTREVQRTPTRRTTPSRLSFSSPKTSSPATQPPPVSSPVIQEPEEVVETSSVVSESPSSQRKRSVDSTQSMSSEPVVNRRASVGKRRRTSSAASIAEAAPPNVKPPPSTSPSIPAKDHMDPSLHPTNTVPTPWAEMTYQSVPVININADGAREAIQSLRYNGTPFILEGYSGWMRFAKDWVLKDGSLDTEAFLRGIHDVKVPVIERNYEDTNPIKTHLPLGYYVRNYWEKGTAEYYMHQWQFPLSPKAAKLLCYKCDELPVLGDNLLLYWLDAVRGDNPLQYFFMGQQRTNSRMHQDPGGLDITIAPIVGTKRVTMLHRAAAQLESVHDNVNFHTIDLNKVPLLAFIPAWRVDLHPGQMLYMPEGTFHACENITACLSYHRFHVDSINLPGFLRSFMAQDSPSINHAEILWNAVHDVIASLEEHYYANNQKVDKRDIFILRKLDSLRALRHASCILSLEEAVPTEDSWDWRKLLEDIDHLLVRLEQPQTKRKSKNAEDEETPAKQAAVATAAAFTAAVKTDSVKPKASAKQPAKQPTKPAAKSNGKGKAPASKQLTIAAFAAPASSPASVSSPESTHWDSLDLHVGDVLGVQVHEKRNRAQVLKIAHNMELVQVHYVEWGSIYDEFVPVSSLYHRTTSSRKKRVQYKKAPAVHEPVLAKWGSAGELYNAIVLKVLRSNAVYVHYLKFENDWDQWILPGHIFKKYASTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8I0</accession>
    <name>A0A8K1C8I0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_010081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8I0"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04332">
        <property type="entry name" value="YbaK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015003">
        <property type="entry name" value="DUF1853"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08907">
        <property type="entry name" value="DUF1853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="839"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="YbaK/aminoacyl-tRNA synthetase-associated" evidence="3">
        <location>
            <begin position="1055"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW58522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1181" mass="133174" checksum="CCBCC70CF3B052E6" modified="2022-08-03" version="1">MVEMATDAGWYALSRRFYGRKVVRDLLWSVTSPHVINRDLYPVLPADFGLVEDEKSCELLVQWLDDLQADPTHLFTFLQEKTKSKKTALALGVYFASLLEYWLRHCPVLRVEKFENSKQIISATYQTLGQLKFLFRRFFDPASDSFDDFHVESSVKFFLLHPLDEQFKQSTPISESPDADTSAESSFYPLEQFVGPHLGENLAWRVQEVARKLDMCRGESVQAWLRDHYSDNVLSRIVLRGYLFYPLRLFASTSEVTQGHDWRFHANPLDKPTKDVRHNKSIGADHLRGWWTSDLEAEFVSKVDVNDKERIGESRFVVLPKLHWLSPVIADEDPADSNRVVVTGEDVLQIETVEALTLTEVIAHARNHFATLADSTEAQNRGGVVMPLLVAEIIRCQPRDVEFDPSIKRWKELSRGFLLDPKCWDPLPLCHDAVRFKRTTHQANAAVNTREYEGRREWLNNGVIKPTDREAELLRLQKMHSFADMETLTAPAMCQELLKVVDTRGHANLKHSIVNVLQYQAAHKEQCDGVNSVLSYVLEGLKSLALEQSLADSKVAQRVGHLVLDAVEAMKEIKYSSEDRDASVDFFLLIASDEVHWSYTNLALRLCDMILSRGGGDSALSSPRSQAITDVLEKLLTHQNAKQNALAVEMVRVFRRETLTDERRSRDILDLLIELLDWQNAERLVTVTEDVELLSVLFRQLSRRGMTKALKRLRRLITRLHFNEDESLGDPAGSAVSRLPQHALGPAVDVEANRELVATQLPTFRWEFVDSSSQLASLMDGLHSIREKQEPSIIGLDCEWRPQAFINHNGKTTSPGDTLGSNQGDDDEEIDEEVSVGADEGVSVYQLSIGNITYIVDVQTLGEEAAAPLEMIWSDPSLFFLVGFCVSGDLRRLHHSFPSVLGKRSESPLLVELKQMALYRQLPASKWGLSQLYETCFGEQLDKEQQCSDWALRPLSTQQLEYAAMDAFVVRKVALLLLADVVESKPLAEYVRKFAVVTTITHTERELGHWITTLEPLTTSHVRVSLEACGLQAVEQKIFTLDKATWDGCARQESGLIVKTIAVVIRRGKENKDIQHAHYAAVVLHVERSIDMKALSQAVDAEESDLMLADKETLLRVFGYRRGSVGPIGLREQDAIQVVLDAALLQEASILCGAGQEDVVYPIHPSTLVETMHAQVAGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8K1</accession>
    <name>A0A8K1C8K1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8K1"/>
    <dbReference type="OrthoDB" id="95795at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="211" mass="23228" checksum="C9EFA27D0BA32E5B" modified="2022-08-03" version="1">MSKETSSNIVGKTANVSLLELGNLLLDDPAVKVDRRLSLSQAMGSFSKSPNGNIVASMRRTKAFPHGPTVSDLPTAEQSVHANELRPQTETSPTKALSSSDTKHAGSPSAESVLQTLQQRLTHEEKVSFVMKMSQVLFVCEFVVLIEFTEVIVPVMYSIYIAAMSHLVNRAYYPQLANMSDSHLHRTIGNVLTYSALEFASFLLITIMLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C8V2</accession>
    <name>A0A8K1C8V2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C8V2"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="177" mass="20517" checksum="C2ACBC3CDFF268F8" modified="2022-08-03" version="1">MTADAAVTQRIRIRAYRPEDHKTVIELFLAGMHSYITPDLEHLFDDAMAESLNGDLASIQETYFDKGGFFWLATIEEDEKEVLVGMVALERKADNEGELRRMSVKAEYRRYGVGRLLVSHLENWAKKEGMTKVWLGTGGIMQQAQKFYQSMGYKHFKTEKFMEEPPLEAYFYEKEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAT3</accession>
    <name>A0A8K1CAT3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAT3"/>
    <dbReference type="OrthoDB" id="206755at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058678">
        <property type="entry name" value="ARM_PUB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46241">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46241:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25598">
        <property type="entry name" value="ARM_PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U-box" evidence="1">
        <location>
            <begin position="198"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="40631" checksum="3207A37F17CD6BFD" modified="2022-08-03" version="1">MKFVTGGAVDVLIQMISEPSTQCTKALSALASLAGDDASRATILEAGVLELALPLAKVELDCGVAATKVLSALAVHAGGKAKLRGVEEAPSMMFDALDNGTESHKIYAAATLARILDDDEATADKVATMGGVEKLVTIASTQDGALRNNAHFALDNAFYSSKEAKKIAVEGGHVSLFVNLLKMNVKPDTIVYSLVNLSEQDGLAVTEAGAIPVLVDYIRNEAASVRDCAVLALASIAYMNDRLNAEVVATGLLPVFLDMMRTGSTVEKSEAASILAVLASDATIRPIITALTGITELCVELLKSDEEETQVAALRLITALAEDDHVAVQFVASGAISSLRSFLSAEDDPLLLATKAIGALRFIHQSADSAQLKEHVELALSRLQAMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB38</accession>
    <name>A0A8K1CB38_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34199:SF4">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34199">
        <property type="entry name" value="NUMOD3 MOTIF FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="4">
        <location>
            <begin position="231"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="800"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1743"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="809"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1768" mass="191095" checksum="2999E8A706FB74ED" modified="2022-08-03" version="1">MDFLRLLSDDLQALRAETKKKYPVVKEAVDKALETLPYLQKQYAALLRVENAPGPGHPLFKSESVLRPFLLACNHTNASHKILIQALVSIQRLVSWDAIEQSSVGSILRVLQIQAEKNTNVDVQVKLLQTLLQLVTLGYEEKSSDVGSLSTTNGRNASAAQSTTAAADEENALVGNEDLVMQAIWICIHLHGSSSSASSVVGNTAAMTIRQVVSLAFGKVQKSREAKQVGVLVFQELCFMSREESGVWLKRTATSPMSIALGVELLETILSSHARLFREDAEFHAILKQHVCSLIQSALETGCSDVKNINSSSSSSNTATSALSLSSSSSNTGITAPFFPLLVRVMRLASVVLCNFSDVLPDVGSVIIRGLLEIVSTGAYYQPGSAKSPSHAKLTAQEARSFLSHSNSTSSNIGGSGGSHHTNINYVTWPVLLALEVLNRVSMEAPMVAAISNYSDGSLGSVARTVSSVVTTSPPMDFRLYAASDVVVTPRSGLEFLNDQEAPMLQPFFSAIRVAVSCLSNLIASLFDLSRLIQDDAIQSDSLASHGVNVLAPYALHAFNTTMRYCREVELIQVSLKSYHVLATIASRLRANLTAYVASSGVTGISATLLIDASKKLDEVVLSCLRALCAFSFPLPEGIKGAARSGAGGSGNGTNANSSSGGASGGDYYNEDGADEGESCVVTVTWREVHAMKALFSAAHLMEEEMIEVEWCTLLEGFEIIVGLTDVKVKGGQNRLPTRSYRITGFRVEDEDVEQQLVMLGSSIVELFRDALKLSSHALRRLTAALRKVCWEQLGLPLPSSVTPATRASSTSISETTTSSGDGAVELPQLSASHQLKTYQNFLGVGLSGSGPYLPSFVLRMLTQLATNSKRCFEDVIQELLLMTTYSVAPPATSSQFPQLTQFQVFTTDSILQLMQSALQNTINSLSPTSKLPSDASLDEIDAHARSQASEPHIFDQQELFKPLLKLVRSDLKDRALVGILDLLNACGHLIGAGWPLMLGAIQEACEVGEGKTQVAAFKCLRLVVDDLLVSIPRVYLPNCVACIGRFACCAKDVNISLTAVNELWSVADIIGKQKARVTTMPSQWGCAFAELSQVALDDRTEVRNSAINTLFGIAATYGAQFDLTEWQLFVDDTVLPLATKLHQGRTMLSTNAPASNLMLHHSRDSAEKQWDESRVLVLTGISRVLQTNCNVLLSHTQWFARVWQELLKHIALNAARGMSKEVVLAAVNTLQTLLQVSSAGDFDQIAQSQPVRAGAGMRVVGGALVASSNSAPSSSSAKRAPTTPVLRDPVLWGTAFQQLLRLCNDRTGDGSNTWKEDEEQEIASAVVSVLVTLYTQAKEYEFKDARNVLQLLDLFQVLVMRHVLRDTSQDSGAGGKVVSNVTTNSLQSRVLNAFEECGSFAMHPEVHTKALKQLVEYVTVSSTQELVFFTRHALMSLAKLFASVSSEARRDCFHGVLTSIQPFLQVIDGSSNGVNGSGSPDKPKSAAQKAASQLWKHALRVLLVLISHGLAAVRLDNGHWRELLETITHFLEPSTGQLPAFVDGEEDEALVLSVLECLGDSVIALFGGASGSQVLHETPQQYTEFSEALMGLLCSGFDGKDHSKPLIKCCVRQLATLSIQQDDQRLSRYARSSLVDCGTRALETFATLEDVTRSDKSVPSDSEASVSTAATVLAARDRVVIVLNSTCEVELNPPHVLALFPALCRCITSSDLEVRQLIQRLLLQSRLSEFCLELVAPQQEDGVLSRTNSQRRDSRTSSNGGLGFMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBI6</accession>
    <name>A0A8K1CBI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="159395at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016316">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039034">
        <property type="entry name" value="INPP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187">
        <property type="entry name" value="AGAP000124-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187:SF11">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="746"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="896"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="949"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="746"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="912"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="952"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="972"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1438" mass="157962" checksum="51E6920C647D9DEB" modified="2022-08-03" version="1">MASSPNLIDFGDSPRDAPPAQALSFGDDPFAVSHASSGSVADDPFAIVAASTASAETTRSSIDMDAPSSSRSTFSFLNRPSLETTRPSLSTLPATVVAPPPSLRVVEPTELHFFVSCTGVDGNYIQTATRSAQTLMRGALSMLAQTSGGKNRSPRSKPPTEVTVEVRVTREFALVGHEHEAALTSSALLESESYWSERRKSRNPHFAVGFNVKCHLAAMRDRHIQIMVMIPDENGSNKNSQQFGYAQTSFQELYMIATSGNYQQTTKLPVHSTVLEGATVEIRFADIHAWKPALFHGYNSVFHSFLFYPLMKESQTLSHAVSPKLALEEVAEVDYSVKIPVQLLKVCHFELKQMHEEWKARYNYNRKQSRHFEDDAEALNFGHDVFRVQVICGRDLSGSDSHGREGSGSNASRPSTFSSITGGRNAIMNRIKTASKWGGGSDSSDMNSNGGDAVSPFVVVKYCDGIGGVRIEQIVGKTNTEYETAAPIWSMNKSASNCPHGKPNLKFAVSPSLPSRVDISPVNQLKQFLFYRPSVAQHGQEIEGWLRFEVYDETYGIMSGVENELVGEVVIPLQSVRDAMTVEEKIIWEGEDGTTERRAHSVHSLTLVDWFDVRSPTNDAVRGQIQLRLNILLANPMVSTTTDLLGDGSDPVLSPRRQRLAADCAPPSSNPLENEMPLEFLHPHVLMLQHQISEVTNMIRLTEHLVEQKKTFKSSQHKKRADIQGIPTNLHVSYFRIYRNYASPSSSVTTSSSSSSTSTALPPPPVQTERRASTEDLLGLGSPLAIPMSAQVSTAAPGGAPIAPLSLTSVFQSLQERAKFAESHVTITCGAPTAHAMGLSDYGLREMELEIHRLQTLLDRCSPRFTGSTHNVISQEFVSEDAAEFAFSSLPEEFSYEDDDSVAGSPQVQDQTPSADAASTSASPKTSATPTAQQKKYSNFAARAVAGAKAKTVGRAKRNSVGKPPRTKAKQPANSDDNATSGPDIRYPSLKTEPDDGVDPMTSVTYAVRLLCRLEMLRTEYYLRKSVSVAQSVSSLVTCFVAKLDLCLQEKNSAVIEQMAAIGFLIGWESLISSHGKELRMLSDAWVAIKCLETFAFQLHEIETDDSTATMDHSCQDVVLEKREHVGYTIRVPVPSPLFRELPENLRNGELISITSVLFTQGINEMQSLANMVGHSGVSIQSKINSTSFRSIVEYYNRFNSTGLTLAESHVGSHPDEILRNLRVSVESENSASKNTGILFHAGDAVRSLNGGRITYCKSGKDRTAMSVTLEQARLLVQRKRHVLQEIMEVNNGGSASDAGPLEEVKYVANTMREFGVRIDIAKKNVGRYKYSFNSLQRKLLPEIYRPPMSTIQDMEELSVEVVQALVVLLLQGELSLLKSLKLGLQGTFTPLHEDRTYEPTLQDYHCGVEYGSKRAIHCLHNATKHYLVPLESHGALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBK7</accession>
    <name>A0A8K1CBK7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBK7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="183"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="444" mass="49159" checksum="E7DF27E80307CA7C" modified="2022-08-03" version="1">MVSVRLLAPRPTRLLTPVKALRLLQSRLIAVLVSLNAAKLRRLLLRGGSLYGAFALLLGGFYRHPLELVEVTARVNFTIVRTVLAYVLRGCKPLYPEWTLGFEVVRAVVRLTLSGYGDRLLLPQNAQHVRWQSEWVGTALGFVSTRQLGTSVEPFQHMGLEHLWIRSRTPPVAKSGRVHRVVVLYYHGGGFAVMSPRWYIAFASEVQSRVAKLLHAQLGEHDDDAAIHVQVLLANYRKIPEHPYPLPCDDALSMYEYLLTHEKLSPSQIILGGDSAGGALVMSTLLRIRNHQPVNTPLAALLVCPFIDMESGGNEHEYPHCIIGDRLGIAIYANYLPKEGDVWSWGDASPAHCDLQGLPPVYIQAAELDYLLPNSKRLYEKAKADGATDWTMDVHKNLPHVFSTFPTLLLPSASQGLDALAGFAARHFASSIKKTQDGHVALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC95</accession>
    <name>A0A8K1CC95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pseudouridine synthase I TruA alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC95"/>
    <dbReference type="OrthoDB" id="10256309at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02568">
        <property type="entry name" value="PseudoU_synth_PUS1_PUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.580:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041708">
        <property type="entry name" value="PUS1/PUS2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF4">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="8">
        <location>
            <begin position="272"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="453"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="486" mass="55118" checksum="ADCA13C70D3990E3" modified="2022-08-03" version="1">MYSVPLPGLQWALAMGKRKTHWAVRRKNKQARVDAAGGKLDKSDAERPDRRAGFPEEIHPGSYAALRAKDASAEAKTDENASALAPKRRYGMWVAFCGKQYSGMQMNEGVKTIEAELERALFEAGGIAEPNYGFLQKIGWSRAGRTDKGVHAAGQMVTAKLHVGDDVPAFLQNVNALLPDDIRILHMVTTTKNFNAKMSCDKRTYEYLAPTFIFGARETSKPSDEASTWTRDLFDHEEGINAEVSVDSSSLAAHRAYRMDDETYTRLLRVLKEYEGTHNFHNFTSKLEPTNPKCKRYIMSFGADKPFVENDMEWIRLRVVGQSFLLHHIRKMIGTAVDVVAGVTDVATIAKAMELDKMDLPKAPSVGLYLAQAHFDVYNNKLQDAVQAAHPPLDFANDVNVVDKVEQFKRDVIFKHIIGHEEATRTYAKWLKVLDALPFDYVSRPLEQWKREKEELSSIKSRRERLEAEKNMRQQQQEAHEREDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCK1</accession>
    <name>A0A8K1CCK1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCK1"/>
    <dbReference type="OrthoDB" id="153948at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="40415" checksum="059A95D85699835F" modified="2022-08-03" version="1">MADGSEMTSLATDMQASVGEKRRMLDEISKSIVHTRRCNKRALCTCLLRLESVFFQRNLSKRAARRSTRMTVKGKAVVKNLQQFEMDMKSLITSFLTPVELTVLGMVNHRMKKDVEEIAKNEAEAFVNRTKREHAIIEAEKHEAISWSRYMHVQKTCIHKMFVYYTGYRTGAMRDQYKQWAWGIVDVDPNEPSKTIMPNSWKFHDHQPWIPRRANGKNGEWILREPYKFGKAPKSFVEKVNEWALMIRPGSHITIAFQQPDATEVNWWEAQVWYAWRGDGREDPAIVYDPENDVNLTMSPNDLLAHFQANPTHVIDVCEVPKSVCRMCEKKGKSFYYCHLEKGHPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCQ1</accession>
    <name>A0A8K1CCQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">40S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCQ1"/>
    <dbReference type="OrthoDB" id="564720at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="18148" checksum="F7A1850B56552CD3" modified="2022-08-03" version="1">MSLVIGPDFQHILRILNTNIDGRRKVWVALTSIQGVGRRFSIMICKKAEVDITKRAGELTNDEIERLVAIIQNPLQFKIPVWFLNRKKDYKTGKHSQAVANNLQSKLRDDLERLKKIHVHRGLRHWWGLKVRGQHTKTTGRRRQVVGMLAAITGQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD61</accession>
    <name>A0A8K1CD61_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein regulatory complex protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014533</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DRC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000078">
        <property type="protein sequence ID" value="TMW61072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD61"/>
    <dbReference type="OrthoDB" id="536093at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042815">
        <property type="entry name" value="DRC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31598:SF1">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31598">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="389"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW61072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="450" mass="51822" checksum="4260942C8D7B23C5" modified="2022-08-03" version="1">MNSAMDVEAERLVGVLERTVDALELLALLPSGETEATWDAIVSAHEEDARAIESATATALREHFDVEASLVHGTKRTKMGERPETDHEEEDKVELDDEEDDWSNDAMLQYPKTLHRAVRVLGHDKAARDTLRRLSATQVSPDVARFIHLWTEAIIHTEQWLGSSPEQDEHVARKLQDASLRVRELEDDRRQVAFELAAEREARQEASFKHLKSIATLREQLREIQRTADEALQSTRRTAEQDQQSALARFEMGRANATEKWLAVSRVEQRVVEMNQQDEDDERRRGMRLGVEYQELLRRYDEEMAALDAAIAEEKRELSSLGGETGILEDHFDQVDEDRHYQLEEQRLLEALERKKRLEQLNVFRLTQRLQAVVRGFLVRRRVRLEEQLKKKRKKKSKKTLKKKKYTSTKPGRPSSSPTKHKATSPSKPPTRPTSAASRPSARPRGPTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CD67</accession>
    <name>A0A8K1CD67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="10">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000788</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CD67"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001544">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001975">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="97"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="287"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="623" mass="70701" checksum="20AA8D90479EAE55" modified="2022-08-03" version="1">MERHEAELVEIDDELQSIEEEMSVLLMRQSELLDRRKEIRELLGQDGDGDAVASRQERVEELVVDWNGAFPWTDEIHGILKDMFHLDSFRSVQEEVINVTLSKKDAFVIMRSGGGKSLCYQLPALYDKSAGFTVVVSPLLSLIQDQVLLFNEIAGEGAACHLSGEQTRQEASMIHKQLLDNNSPLKILLATPEKIIKSKLLMSRLEKAYQSGRLLRFVIDEAHCCSQWGHDFRNDYSKLGILKRQFPNVPILALTATATPRLVNDVKTILEIPRCIFFRTSFFRRNLLYEIIEKPDKDATALNVLAELVMSFGAGNTGIVYCLTRKETEQVAQELVSRGIRAACYHAFMENKAETHTAWYEDKLQVVVATIAFGLGINKPDVRFVIHYTLSKSVEGYYQESGRAGRDGEPARCILMYRASDVTRVCSIANAEAGGMRNLRLMIEYGENFTTCRHEIMAKYFGESFESEEMCQKSCDNCKRSKDDVVTVDFTEHAKVIGQIIVNAKNLERRLTLKQLVDELKSRKVVQEHAQLDPFLSTLPRTECEALIINLILRDVLQPEISYTAYNTICYIVDGPRQLLRGTEVHLQRLRASLSAAPSTRRPAKKRKADMKDDVDVIELSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CER2</accession>
    <name>A0A8K1CER2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CER2"/>
    <dbReference type="OrthoDB" id="115782at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21771" checksum="2A9B577F6BDBF0B8" modified="2022-08-03" version="1">MIHPMAEDSNCGAFVVKPGVDQQQPVRQIECGKWSVGFWSCCDHCIPNCMMAWCCPCVSLSQIYARMGLMTYSAALVRFFALALSVILIRYVPFVSRRRLTSSTKTLSGNAWLLFIVVQQITFIYAIVFARRRIRQRFKIPGDICEDVCLSYCCSYCAIAQMATHVKSYKPSSCNFSGPDVLPAYEQWTEHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFS5</accession>
    <name>A0A8K1CFS5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFS5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="360"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="443" mass="49390" checksum="A795F83476F7A50E" modified="2022-08-03" version="1">MTRTPVSETIPNLEFSPLEQHDVIEMTASVIADALRVERQYLSRYGALSKNEWNEVRGGSGGMRIYMERRRSGSQRWSTSTSDSGAESVELEEIDWIDARSVANSIYSDSVSGSFSSDSFPTRLVDQVRADAESSNTSSSTSSGGLCATPDSVYSRVPMVVGAGQVDGCLEDVAFGLYAGDKVSWKERGTYIKDGYNYSRILSTILGPTAEDPYRFLGVKWFMREEKNLVYGTMIQDRDFLVIEATGITQDGKGEPHGYYVMHSFRHPLVPEYTDRKILRCEISICILSRQVSPNKVHLFTRGFIDPKGSLTPSMAIAVSTKRLSICMKTVEMALSRKLVWLMKQRQRNRTELEAHHNQAMSSRKCEVCAKSFRFLSGNLSFCQVCNACVCSKCTVQRKVVVHATPTTGTKRLLPFCAACILEVKHLPPHQVALDTNLPRVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CG75</accession>
    <name>A0A8K1CG75_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycoside hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005549</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CG75"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034411">
        <property type="term" value="P:cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF2">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035437266" description="Glycoside hydrolase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="423"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="423"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="52864" checksum="7180B924669F0F0B" modified="2022-08-03" version="1">MKLLALLSGLLLGLTVPMVTAATNPIVIKNYKMYDSVTGKYFGVRGVDYYPRANTGTKYDVNNYDFFTDDHEDIWGPDIQYLADLGANAVRLYAVNPSLSHDKFMAALSAKGMYALVDLGANCKNCAITRDAAPTCYPSQLKSRGEMIIGAFAKYDNVLAFSAGNEVNHVVDDPNTNAPCQKKFIRDMRKYIDSCTSMRKIPVGVVLADTNRDANALYYNCRTDTSDTYENAEWYGINVYVHCDGAVTDVSNAAGFNQLLSDFTTYKMNIPVMLTEFGCLSNSFATVNEYEAQRTWLQAGWLHSKKYRAMFNGGFVFEYSTENANSKADAPYPFTKFGGQNYGLGYYSPATCDHDTVKCVYKTMPNYGFLQTQYKATNYDDEPLMSSFVADANKKDFPSCPSGFATLKSITWPADSTASLSCPTIVPTPGTTPAPTTKTPTPGTSTSPSPSSNSGEASIMRTHGVLATFVTSCVTALLVATFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGP2</accession>
    <name>A0A8K1CGP2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGP2"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001667">
        <property type="entry name" value="Rab family gtpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="21610" checksum="213BF8E0AE5DC1EE" modified="2022-08-03" version="1">MAQGRTCHFKLVLLGDTAVGKSCLVVRFVRDEFFEFQEPTIGAAFLTQTVNLDDGLTVKFEIWDTAGQERYRSLAPMYYRGAAAAIVVYDVTNKDSFTGAKSWVKELQRRGDPNVVIALAGNKADLEARRKVDFEEAHQYAEDNDILHLETSAKTAVNVKDLFVAIAKRLPKNPPQPAGDAFIVTPPSAPKKSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGV8</accession>
    <name>A0A8K1CGV8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Myosin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009766</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGV8"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051059">
        <property type="term" value="F:NF-kappaB binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071356">
        <property type="term" value="P:cellular response to tumor necrosis factor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051070">
        <property type="entry name" value="NF-kappa-B_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680:SF3">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR CACTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PDZ" evidence="9">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="580"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="647"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="10">
        <location>
            <begin position="709"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="126"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW62273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="89016" checksum="9089B6837C0D8CF1" modified="2022-08-03" version="1">MAQTRKSHSNSWMEEQAAEYADLVGSFVESVHDEDTDEMLEYQLIWEGGDLGVALTPLENAEAGGVMVSRITGKGFPFGIKNVTAGDILLSINLRDMTTLALNDVVAYLQECDLPATLRFKKVAQEEEKPAAAPPAVRRKSTIIVTTDGPTSPTGSKAPPIPAASTRYSQKATPATGVGSSTRYSNAGVRGSAQHGRMSNAAPPPPQPRAAAIPPAPQAEEQPPAQNAGPVQPALAQFPSGMLRHTSSRKKGQTPLAQPVPAPVQAPVPTPGSPPPSPVPEPKKDAPAPVPVPVPAPAPVKKAESAPVPAPAPVPVSAPAPEKKAEPAPLPAAAPVPVPVPAPVEATTQAMQRATIDGRDSYDIRGSWRSSEDIDDARARQQAAESSDEEEEEGDPFVGFDEMPDVQRDKAQSVAMLGDYSTETNGGIPILPVKTSVIHVIDGVMTEQDEISDDEYESQVRMSVPRSPPRSPARSPAHAAAPAQDVPRESVRLTMNRGMQEPIMKSQPVGTLHELCSKGNLRGVMQHLKTHGPDALVQREANHGQTCLHLAVKSGNVQLAKYLIEQYDLPEELVNIEDDKGNTALHFAATKTPGMVHLLLESGASANVKNSRKLTPLIISVITSKNDDIIISRMLLKYGANPNDMHDSQTVIHTAIGSGLLKIAGALVRAGAKMDVEDSEGRNVFEKLDKKSVRFLISHIYFPPTYITEKERTECMLCHKKFKFGHRKNNCTHCGRLCCTECSSLSVEMYKFPMGFPGRVRKGAANRDLKKACKTCYGVFKERGDTPQKEENRFMSRVIGIEWDEVNPNKLQSQRSAGRRGEKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH91</accession>
    <name>A0A8K1CH91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH91"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="161"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="54567" checksum="E7924CAC5E3B3119" modified="2022-08-03" version="1">MAGAKSERRSAAEAAQSNKRARVEENAVKDEVKVNLYTGFEVPVEGFQVERISIHDITPEDFFKRYVATRTPVVLQGFITDAKFTAPQKWTNEYLRETAGDESLKVEERSKVTEKFGRGVEVDMQFKDMLRLIEEGDEMHYLTTQDVEANEDGRPEIMAPFVAKLQEDFPLQPALLGNLVPQNINIWMGNNKDGSSSGLHHDYHDNLYILLRGKKRFRLYSPADTEKMYTRGKLVKVHTNGRINYEGEETTAYGADPMSEAAALASIEKEDAERELALAEQAVEDGEEGAEARLAAAEDRLDKAMLSLLRADRDEDDDEEEPEDGEFGPFHFEDEDGEDEDADDEEDAEDAEDDAKKVDKTVKDPVNFSRIDTSLLKTPESKEALLKEFPAFEEAKAAFCEINVGEMLFLPASWFHEVESFGSKDGHLALNYWYHPPDQLDNFDLPYSSPFWPRDWEMRCNGVTAEDDDEVFDDFDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHI7</accession>
    <name>A0A8K1CHI7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHI7"/>
    <dbReference type="OrthoDB" id="165533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="58334" checksum="D9520842E6AAFAF8" modified="2022-08-03" version="1">MTNMDAQLRGRALLSTHEAWTLAMTWEKALRTKVVLKMCEVSERTSILKTYAWVHFEIRSPSVRLAEIVRATTLVWFALSSVPGFQVHENPIFWKYVLGYLREDKTATRFRASGGWSPPAEHYNPVRDASRFVDDEFPRVSLAFDAAMCRVVTGLTPCTDEDTRSKLHSMLTKLAPLVDPVQAQHTIALKLDGYYLKSVQAIEELINDINKLDRLQDAATSIWRPRFSIAELCSFNEVNPAMRLPVGCEVFRYYAKDADPPAKVADEVLSILHAHDKPFARIEILHVVRWALTASQFAVICSALPHARVLHTLDLHEPVHPMIERVHLSDEEMVWLGYALFHPDTVTSSWKRLNVGDAISKCKSAPLILQRMARGNHLISVLSGSFDQVCPAYYSAHFSDNTEVQVGSTVVVIGANARYDLCVSSDDLQKLPRLVSIVVPGFGLGTVEKSRIKTISARPPSTSTLTALDYLPGEDLETRLSTLRLLGPELTFLDATSLDRIDTATVHEILDMCPKSRLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJB5</accession>
    <name>A0A8K1CJB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011551</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035480321" description="Heme haloperoxidase family profile domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="10">
        <location>
            <begin position="35"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="10">
        <location>
            <begin position="533"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="10">
        <location>
            <begin position="1039"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1028"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1568" mass="170765" checksum="B9B56A8A1227DD52" modified="2022-08-03" version="1">MVKMLLLTLLASVVALVTAQASGPGTVGPNSALAVGEYYRPLPPVGSGRVRTTAAYRRGPCPAINTLANHGYINRDGKNITAESLVAAAVKWFNVDEAYAATLVRLAKKPVFNLDDLSVHNNVEHDMSLVHKDAFFGQDPAVVDPELIDDLFGHVGSSGILDPWFFARTQQRRLRECLTSNPQCEYSNEFLLGVTLGRQGLVMRVMGAKNEEAAPIKTVRAFLTEERFPDGWVKSPKPIKQDEIQSTRVKLYALLRSSGDWLADGFGTSSQLLRSDANPKLCLQVTGKETSAVDTPLAMVKCDSGKGEQKFVLDEKKRLIVDHSELCLEVEAGSTVAGAVVRQAECGTTKQQKWMYDASGRLRPVHAPDLCMNFNETLVVMKDCGNSTEQRFFSYYANFQPSVSHITSIAVPTLCLQVNNASTSDGSAVIAESCQSATTAQQLTLDDKKRLVFKHTDKCLDVDGDNKLVQNPCGDDTNQWYYDSLGRMHPSSAAGKCLMLPNEKESKLSLVDCTDVGRQKWFVSDTKDADVRPDDQFYRPNFFESSGKPGTSASYSRSPCPAINALANHGYLPRSGRNITSDMLRDAVVKYFNIDPSYAQVLVELSKKTVFDLDDLSLHNAAEHDMSMVHADAFFGQDPAVTDPSLTADLLSHIGSTNTMDTLFFARLQQRRLKDCQARNPQCDFSNDFLMGVALGRIGLLTRGMGAKNEETIDMASFRSFLVDEKFPAGFTKSKTAITQADIQETRIRVYSLLKSSAEWLVDGFAGTASVPVITDADHTLCLEVGRGGADAGAPLMVAACDASMDQQKLYHDSKRRLMVEKSSMCLSAVDFGQTEGTGIVQLECNDDSNQQWTYDASGRLRPAHAPDLCLDVSPVAAGSTAVLRSCSAEKQQRYYSIYSGFHPNVSHLNSIPEPTKCIGLFNASSIELSAAVATTCDPLKTDQQITLDANNRLVFKHSNKCLAVLGQTTTIIQKTCKDEPNQLWSYDSLGRLHVAALPGFCMELSSNATTSVALAECSDNNYQQWFASDAKDPNNRPKNTYYKPNRDESSGRPGTAATYSRSPCPALNALANHGIISRDGRNISRNDLVGAVVATYSIEEDLAKELTSSLDKDYINLDDFSTRGQFVYDGSFVHADSYYDPDPAEVDPSLVEDLFSRVGSKNTVDLVYLAATQKRRDDAIVLGPNSVESSEDLKAIRYMKPGLLLRVMSGKNIETLSADVAKVFMAEERIPDDFVKPSTAVTQAEVEGSAAKVKELQASSGDWLLKGFSPDKEQIYSITKDGVRCLEVVEREFALAECDAENSKQKFTYDSSQRLALEKVDATTNCVDVVSGAAEEGAAVQQVECTAFVHQQWTYDASGRLHPQHAAKFCLEVAAGGKAVVNKCNDHAEQVFFTAYSSLAFADKQLTSAVDSPSLSKCLALQDDSNLDAEPCDKSESAQLFTFDAGHRLLMDEQCIIVSGGGDARADALAGVGECVTDSKTQQWFYDSLGRLHLKSSPEFCLKAGESDTESVKLAACAATPAQQWLVATLSTWSYGAGGDSSAIHGASPSSLMLTIVSVTIAWLAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK87</accession>
    <name>A0A8K1CK87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
            <shortName evidence="6">RNA polymerase III subunit C6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK87"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028763">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR028763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="295" mass="33423" checksum="DC4DD1E462E7440C" modified="2022-08-03" version="1">MATNATQALMNRFVALLRSYPEPLTDAEVREYFQSEGKGEYERLPSVINALMSEGRIKIFQKGNVLSYGVVGAEEAERIKGLTIEQRLVLQEIERAGNKGIWTRDIKTHTNIPQQIVTKTLRVLESRRLVKSVKSISSKNKKLYMLFDLVPSTEITGGPWYNEQEFDHVFIDTLSTFVYEVIKASGMSTLKAITDKVHASGISKVALGPEEIRSIIQTLMYDGRVEEVRGVRLTPGQTNHETKYKISQEISTFNYLSETPCGVCPVFDQCQEGNIISPRSCLYLTKWLDLKDLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK94</accession>
    <name>A0A8K1CK94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_011489</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK94"/>
    <dbReference type="OrthoDB" id="10066789at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035446839" description="Peptidase S1 domain-containing protein" evidence="5">
        <location>
            <begin position="26"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="267"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="486" mass="53146" checksum="A97AF0CA030049B9" modified="2022-08-03" version="1">MSSKPSRMGRQWILVAAVLVTVVHAAAPLPLVSLGSKDVAQACVGVQVSPLHVLVHSTCVKMKGPLTTAQAINLALNATNNTTTQASLEESVAVANSTTIAFELPPGNATASNSSSPVHSVHVLALKKPLTSNFPNPVALPLKTPYPSYLDVDHNATLVSVDVSLLAVTSISDVIYVADEMCDHPVCALPLEVEDRNGQTGLDRWSFVFKHDPIRDAYHLLGVGGDPVTDASGIWGFSWLPQVLKSSSFIDNNVHGVKTVVPIKKEIHGGKDVKTTSEYTEFIAGLRTSQDGETYCGGTLITPKWVLTSAGCKDIHNPTWVVIDTLRTSGKPTEAMKVKRTLKHPNYKTGSHSYNFMMVELEKASSRRPARYSWDKAYKKDTGTAFGYGAVLYQTRHMYDRLRSNKVSVLTDCPKDLKLDKTAMCVQGKISYGDYGGPVMKEAWSKNRILEWVIGNNYKFHTKKDYAVVGHVPVVYHWIGTVINQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKM0</accession>
    <name>A0A8K1CKM0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_014677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKM0"/>
    <dbReference type="OrthoDB" id="164313at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="542" mass="59407" checksum="4B19437456F0366C" modified="2022-08-03" version="1">MSELVESSRELKVDILLDPSLSWDTEFESVRFAYLNAPTQNELLTGDAIINNGAMAGLREGLPMVELLSITHGGLLINASVMGFVLVFFEYAFQILLLADCSSTKFAQSTATKYLLQWPGAFAVFFGLISDCFPIIGLRRKPYMVIGWGVAATVFAAMFIICNLTTPGNGTRDYLLVFLSIFATFGLQIAYVAALAMTVELGQREHLYQRGHLQGLYLVVYYAFATLAHVVTALVIHRDELGITLTSSISLTGAAGMLAGLCALPVPFLLFCLKEDHAETTNGSIVCRAIELWEFLQWKIVYNILFFLCASLFLSAAFDSNVGLAVSFWSGITANTAGWIKVSEFLARFLGVLIFKTVFINYSWRRLAIIGLVSNVVAKMIMGGPIIYDVVRNPWYMCIMTLVSDVYLGVFDIFALVIPTEIADVGREGAVIGLVSSFTVLISIATYTLWASVSSAIGASVDVVSILVDLDETRHKVAIIGVVYVFINLLALGAPFFVPHQKLDAQRLRAFGGHNHFGRIAIVTAFVVLLVYCFVTNVLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKN2</accession>
    <name>A0A8K1CKN2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKN2"/>
    <dbReference type="OrthoDB" id="109592at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="467" mass="51597" checksum="6D8089D04DE3B09B" modified="2022-08-03" version="1">MAAVSMRPHQERALEETRMSASASGSASGAVERSTCTWTQKEVQGQCVLKPRSCYDCLNTKPTSNEVCTLTPSGHCLDMSMYNASLDYRRSGPVGYWPPHYNYFPSTNTTYCAHDDSRCASCRSTTFTNWGSNPSVYCIGANDCVCVAICESSNWESLIQTPLEEELSRQEANGNLTGCAVDKIEDTAADSGSAADEIFIGLPETKMTFANSDPCMWYQNQTFCGAPRTCYDCLNMGLYNGERCMVHSSGYCTSMSAYRLSRDFRRHFASNTTSMLFPSTNTTYCEANDPVCGECRATTFKEWQNATSPPAYCLGNDNCVCIASCESPNWQETVVNLTCDPPVTTRSTKNQLASISTIVTIVVGCVVTSFFALVLLSCFRRSRQRRSGLPGNARRRDPEGPQLELSGWKAMREELINKERDFVAEDSRLTRSSRRPSEGEGQSTDAPAVMVEEGDAYRPASPSRMHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLH8</accession>
    <name>A0A8K1CLH8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009315</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLH8"/>
    <dbReference type="OrthoDB" id="10520342at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004896">
        <property type="entry name" value="PucC-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03209">
        <property type="entry name" value="PUCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW65148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="578" mass="63701" checksum="CFF1F33A9F472265" modified="2022-08-03" version="1">MRSQRSSKRESHVEIFELGGPSFFPIDPSPPPMVITETDRTRDADSLSLSSVESCVPNTRFVAGHSFFNYAQLGSLRPGYGSVNLFGTGYCGLTVQFFVCGFAFYFCSYGFGRILAEYVSGYSSRQAEAVNYVLSWPQCFVVLIGLISDAKSLWGHRRKSYMILGGLISTFFFVVIVILDIFAASNHAVGMSSVRAGSQSSSPDTYVVPFLILSLMASFGIQISWVTAVAYSVELAQREPLRRRGLIQGILVGVYCLGGAFAELLTSQLLVKHEDHVQSRLSLGSAAGVLACVCASSVPCARWFIQEDTVYTLRDTPAASIKRRGSDFWRFCSQNLVYRVMFFVVGHMFLLALYNINARDAVEKWSHVSFEDSLLILVGRRFAKVFGAVWWAYYLKNYNWRRLAAYGSFIFIIPNVLVTTLTAFDVVRSKWLYGVCVSFGDISRAWLLIYVAILPTEITTAGQEGVVAGMCISFQILSGLASLTVSTLLPGISALAVSDDDVMNDDKSTRMTVFLATMMCVGINLLCLLTVPLLPHQKLDAQQLRAFGGYNGCARTVLLVGFVLLLVFNFAANIVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLY5</accession>
    <name>A0A8K1CLY5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLY5"/>
    <dbReference type="OrthoDB" id="72921at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="844"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="897"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="935"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1012"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="Putative auto-transporter adhesin head GIN" evidence="4">
        <location>
            <begin position="63"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Putative auto-transporter adhesin head GIN" evidence="4">
        <location>
            <begin position="275"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="TRP C-terminal" evidence="3">
        <location>
            <begin position="723"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1170" mass="124532" checksum="A6874E7CABC6DA79" modified="2022-08-03" version="1">MNKDTSAVVGGEGKQAIGKPIAARQKFKKVWTHDIVGEILPSRVDHLILSGPGLTFISASTSGETKVKVSAETIDMTSAVDVKSHEGSGLIIKPAMNFDHQYVLTEVQLPLEYALKAISNQGSGTVVVEDKVLVANGPHSDIQIKQTGSGVVRVNSHTPLHVESLDISLTGSGDMQFVSPQVIASKFFSSKITSSGNIRVFVGQLNAPKVKLQSTGSGTLQLAALHVDAKHEVKAALTGSGSIHSLGDVLSTQAVSGTVTGSGALRFVAKDEFITTQVQSLVIGSGSITFGSLGAQCAKASYKIAGSGTINATDFAAQFVEAKLRGSGDTTFRASEEIHVSDAGSGRAFAVSPLPPRVSGRIQTVEAVPSCVDELLQHRSTPRTTPTASNGNGSDDDDDDKKPSVRPTSVPSKTPTPVPSKTPSPTTKTPAPTPTSTPKPTDDGSPSPPTATTAKPTSTPKPTTSTPTPANPSPVPTTKTPVTTPSPTEEETLESPSPPPPTQKPVTAAPASTRTPQPPASSSDDDNEVPAPTPTTRAPAPTPSDDDDASPPPVTRIPTKPPAPTTHTPAPLSFDDGKSGEGLPDVVAPVKPASESEEDKKDITLFNESSQIPTPADPFAIIDIKHKTATEKPTLLEVGGELESATVAPVKYVRGRTEYVVGESATTTTGVIIGGTVVDDGSDTGETPRVIGGRQRTDPTNANTMSASSAAFHDTLRFSSCAFAGVSLALLLFFQFTAVDGTMRWTGGWSPNTWEFAVYVAYLQQMSSISQITLIKTPYFLWDFTDPFAWTSFLIQSDWSSSNSLSSDVESAGARRLTTVIIGGIVAYADRLGSQETDILTNCVVAIGVVVAVLLLAFILSAYFVRRNTESSQYQDSTISTREQVARIQRLRIRSSCVLGLCVLVWFMTLYPLGLYSSFEISMEIQAGLMSTVPLLVATFALVGVSSGGLAYFIRIIWVKDSNELQKPMSLAVYGSLYGHFKYRSRLFFVLTCLVQVLSGITIGSSDAEPNQLIGAIAIQAMYLALVFIFSPFRLSLAKWFTYALGVVKIVNYCLAFAFLYSNDSLSSNGRHVCAEVYIALNSIIIIAWFVRLIGVFIAFMRTYVNTRESLMSPEAALEPLPAEQILPPYRESLSKTMRLDESRNNGPPMVPTLQNLQEPVARGHGGRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM10</accession>
    <name>A0A8K1CM10_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008964</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM10"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="38"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="12">
        <location>
            <begin position="269"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="13">
        <location>
            <begin position="575"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW64797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="911" mass="102745" checksum="58FD5659CB4D4FE2" modified="2022-08-03" version="1">MSTHQTTRRPHFLNSQLAVMCQTTTETTFARLPTHVAPRKYYLDYAVDLERYRFEVAQKIDVDVIKATRTITCHAVDLYVFNVSVEVDGKTVACDEIRYIEKDQSVTFTFARELPAGAKAVLKLECHGFLNDQLKGFYRSEYTQDNEQRVMAVTQFEACDARRAFVCWDEPAVKAKYEISIVTDVNLTAISNTHVVQTLVRPKKNAHIRANTRTDATTEKLWKFAETPIMSTYLVGMVIGEFDSVSDITKEGVLVTVYTPVGRSERGLFALDVGTKALSFFTERFGIEYPLKKLDMLAIPDFAAGAMENWGVVTYRETRLLIDEKLSSFSQKTATARTVCHELAHQWFGNLVTMEWWTGLWLNEGFARFMEFEAVHHIFPEWNVWEMFVQEITLGTAMVKDAMKTSHPIEVVVNHPDEVDQIFDVISYAKGASVIRMLSEYLGRDVFYKGIHEYLVKFSYLNAQTEDLWYALENASGQKITAMANSWTSQTGYPVVTFADGKLSQERFLADKTMKDSETALAIWDVPLTYLSSKKPTEIQQIGIWQGKSEAPAGAHAPVTADATVTGKIPSSDEWVLLNPNQSGFYLVNYSPSGWSNLQRPVRENVLTTVDQVSLLSSVFAFARSGVVPLSQALDFTSAYAQQTEHLCWKEISANIGFYLTIFQQEAFYPLLQEYVRKLFAGVMKQLTWTAAADESTSVGHFRRDVIAMLGRGNDTAVVEEAQRLFQAYLSDRKGSSLSADLRGVVFTITAARGDASHVKQLRELYEASDFIEEKLNCLSAIGLIKSLDLKREVIEWALKSVRSQDIQYVFASVASDAEGAKATWKYVQDNWTALNAQYAPYIVGRIVLSVIARFQSEAQAVEVESFLASRKHHSYDRLLDAALERIRIKAACFQRDHDGLATWLNASSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMG7</accession>
    <name>A0A8K1CMG7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMG7"/>
    <dbReference type="OrthoDB" id="91404at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="271" mass="30232" checksum="A80894C4E9253715" modified="2022-08-03" version="1">MEQVRLEMTASVELHGGDVALFVQELKGIQAEALCEVQTIWSKRPTTAKGAVVTTAQLECERVVADFLCQRFSKLCRHVSSGEVMMVRCKRVHLGVLPLSAANKALTAKSTGRSEQKNQEVALREGVHPMEEARSASLPRSVVVDLLDCLGDRVAEVHDAFTTHAESFENSVRLTMLGLHHALTDICKDEWRAGALAKHNEAKDDAPDRLSMQRLRHLLTRLHTQQRVAFARIPESTHAPFVSYTDFLAIYLAYLQELQTKTTDTSCNARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMU8</accession>
    <name>A0A8K1CMU8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Adenylate cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008137</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305:SF28">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305">
        <property type="entry name" value="TESTICULAR SOLUBLE ADENYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="104"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="335"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="10">
        <location>
            <begin position="1022"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="8">
        <location>
            <begin position="1373"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="747"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="815"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1303"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="834"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="845"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1503" mass="167889" checksum="C7E39456F468709A" modified="2022-08-03" version="1">MKQARATRSEYSLLTQATAASLYNATTPPSTSRTSSRRATTPSSVQNASTRQPTSMEPMDDRSSSTLRKELDLRLSAYLPAVVRRRLERQTTQQIPDTHQTTVVSMFADVSGFTAMTESLAARGPVGAEFLGRHLNSYFEQLLRLISSAGGDVFKFAGDAMLVFWSENKEDTLESLLRRCVQCALRIQSHLHQAELAPGVVLSVKMGIGIGGATIAHLGGVSDGSTSRIEYIAVGPALEQAFSSEHQAEAGDVICSPDCWKIIAKFFDGEPVRLGSAYQKVKTVEKPIRLISRRSSLTSDDPTLHDRMKQYVSRAVWPYLDAHDEFWGSELRDVTVLFINLGFCEEDLAQMLDMQGLQRLQDAFALVQKCIYEYEGTINKFLVDDKGSTVIAAFGLPPVTHENDPIRGILSSLAICAALGKLGLKASVGITTGVALCGVVGHQGNRREYTVLGDIVNLSARLMQKAKSEKGGVITDETTKLYTHDVLHFEERPEIMVKGKNDSIKIHRPYPRMSILLEYHLSSVRAPTARKNALVGVGDPATAAIPRATPIPNVMDNMHRVQVRDAQRRISLLAEKQAANTQTIIESDGFQKIRDTLLQTCSQLNRFSNGGSFILEGDIGVGKTVLLRNALSAPTTESYNVYMGTASPFVTRKPYALWAEIITKCALESYGDTSSYGSDTDLTNTSSTATVTAANLNDFSRDNERRSRIATFVRRKIRDGAAPNTTLVRYAYLLNGILDTNFEEFIEEEETETESHESSVKPLSWDTKQPTMRGRGATRSNQEDEMTSPSKFHMKEEDIAAWFLGLLEMDLASRRDSEVQPPANDEPETSSPDAIDDKESPEDVGESKPEEKESEWKPTGLDLSGILLLCALHAMSRDRATVFCLDNAMFMDEKSWVLTTIIAKYFTNCMVVVGTRPPSLSLAEHTQSSSFRKQLRALKRMKPSVAVAMEPLGPTEIHKLAMQFLKVQVLPDELSSILISRCQGNPLFLYEIIGEMLHKEVIKVDESRYRCFLQVQEPWGEKHTAHFCFHCYVKFANSKEKHRCKSCGYVFCMPCTPKACRKKLPGSTGDPVRHCSNCYTLSSTRRPSADRSLAAAASTVASNSKTAVLSRQKSRMRSIFHLDHHTRSLQPSLNNRIALRPPKTVKSVLTTLLDQLTVSQRMLMKTASVIGSVFEEELLRDSTPIRAHLSRFHQDMEDLERLSMIRRIDNFIAGVPTAKSPSASPDQRVRSPPLLKVKYEFCHGFMQDVIRSQMLCSQLDKLNARISDCREQQQKELRHRFFEKAKDSLNRPVQITIPVAATVGDRRRGSNPHSAVPRDRARRRSLTSIGDIDCSQRSGYTLETSSSSYDDSTLSACSPRRTTQTIKVIPTFVRLKTGMVFVKKQSSLFSHLKFRGLTNARLWKKRFAVLQNARLMLHYDEANGSKPRPGTTLFLKGAKVSACDPEVASKVNCFQVEVNEWTKGKYLMNQKRFFVMGVQSEAEVENWVYMIRYAIESLENQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CND3</accession>
    <name>A0A8K1CND3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CND3"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="25210" checksum="9FDD516302B57068" modified="2022-08-03" version="1">MVLRIFWNVGAGLVHRAINKNAIKPGMGVLYPAVWRGRPGMLDVDINMHLNNAAYLFNSDLARWHWVASSGMLFQALKQRQLFFVSSQTIRYRYPIPPLRPYEIRTEVSYMDDEWIYILHQFVCPTTGKLYAEALCRTTVKSGSARVAGRELIRATSGIDYEGPKEMPTVVDEFLKWDASSRVTIESEEEREKRLAATAKSTRRPQGLLGKITKTWNLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPE8</accession>
    <name>A0A8K1CPE8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPE8"/>
    <dbReference type="OrthoDB" id="437960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="254"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="40616" checksum="494D0F754857C632" modified="2022-08-03" version="1">METTHDEMTEEMPREDEMKRADGSDSNDAGEGDHELSNEVSRAPRCVELRMADRALYRGQVNEASELQGIGVLYSRFGSDRYTGEFQDGHPSGLGVTLASNGGYYAGETHNGFPHGFGVKLNQFGERSIGHWCDGELQGPGMTVDAEGTMAIGHFEMSELSEEQQPEWKSIENHVQRALWSEQQAVTRQERAREVEISVKLQETTAVDVAWFQQGEEIAAFEAEEEQQLQPFLMEQQVRLRAVESDSDRWKFQEAQLKARQKVLRSEINEKRSELSYVAKYCRLADERKAQLSEAERTLDMLQRQLVLLQNQVENELNPLLPPPDDKMSQGSARGSTHSRHSKAQRPEEPMTERRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPY0</accession>
    <name>A0A8K1CPY0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPY0"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="709"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="888" mass="94606" checksum="2AA937DFDD15AF9D" modified="2022-08-03" version="1">MNFLKSLGGFVGASAATGGLPYVLDPPSGPVDAPELHPLPDFQLFAGHARADASHAVSVFKSRQPASQLTQNALKRIKTLRHPNILAFVDGTEVPNNGPIVLVTEPVIPLAQYLEDLRREYGATSDEFQMSVSWGLRSVLLALQFITVDCKLLHGRVNPQSIFVTKGGDWKLGGFELTGELTSDGPSYIFTAFEQFADGNYKAPEWQRREWKNIGNAPSSAVDVWSFACLLFYIFNDSQLRPNELSSASNIPHALRMQYRKAVEADPRRRPTPDKFLASTYFDTPFIKRMDFLENLAVKTPEEKVEFYKDLCSHLNTLPQSFGVHKVLPALKGVVEFGAATAAKNGPVKLDPSASHMLPAMVQIGSSLSAEEFKEQVLPIIIKLFSCNDRAVRVQLLQMMEKFAVHFDAKLVNSPVIFDNICSGFTDAAPVLRELTVKSMLHIADKLSDANLNQRVMKYFAKLQTDPEPAIRTNTTICLGRLASKLNDATRPKVLFPAFSRALRDPFPHARLAGLRSLTACEELFSPQAMAGSIVPAIAPLLLDVSISVREQATISMDLFMKKVMAEAAAMKTREEEQAREQKLRQEVGGSDEHIGATGSSTSSAPSSTGGGGGYASSLTSWAASAVVSNVGKIVGGGSASSTPAPLSNSSSTSASFSSSTPSASAFHSTQQATSYSHQQSTSSTSNAFASDDFGDDEDAWGEDDDLDGLGSPQAPVKTASFTTTTTPSWGSTPTYGGNNSFSSSSSSTSGMKLSVARPAPTPATSVSSSNGFAAEDAGGWGDDNWGGNDLDVDTTTTTKTSSSAFATTSSTTFGSTSAPGSQTSSFGTAARTSSGSGSSGLNVSAAVTARKTASERLAEAKAKRDSGATAMKLTATKKGDEWDDWNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ85</accession>
    <name>A0A8K1CQ85_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014028</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ85"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="121"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="55115" checksum="DD43C752890D57E5" modified="2022-08-03" version="1">MASAGRPTRRAKLANVDYAVLASGQQIPEFSSDDEGSDDDFGASQRQQRSKRRRQGPLHKPRTGCFLCAKNTRSAFVHCDICSRWFHVACGRKFAARSVLGNTSCHECLKESEVSAKSELPRKSVDSLQDVVKLLKRAKKVLVVVGAGISVSCGIPDFRSKDGIYEMVKKMEVDLPEPECLFHIDYFREDPSLFFEMVQGVFASSPSPSLTHRFLKVLQDKGKLLRVYSQNIDGLEQEAGVTKYIPCHGSFAMSSCMRCHARVETKTILPVIKAGVIPTCSALNCRGVLKPEITFFGEILDDKVSTNVAKDRLRADLLLVLGTSLKVSPVAEIPSFVPRHIPQIVINKTPLKKKKLKTDEDEPPPFDAQLLGDCDSIVRLLCSHAKWELPSTSKDQYVRPTVTKHDDSNRICVGKCECVGVADGTLHPSAGKPQEEEESEEDQVVCDACGEALESPDKPKPPVVYRCVDCFDYDLCPGCYPDASERHFGGYHTFKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQP4</accession>
    <name>A0A8K1CQP4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQP4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478888" evidence="1">
        <location>
            <begin position="27"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="136" mass="15690" checksum="763DB25C7366CF4C" modified="2022-08-03" version="1">MVSASKIATVCCLAAASAVMVSTVSAYGYDDYDYGYGKNDYDYGYGKKHYKHHVRKHHKKDYGYGYDNYGYGGYGKYGYDDYGYGNKKYGNNYYDNGYGYGYGYDGYGYDKGYNKGYGNDYYPSNFFGNYYYQGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR05</accession>
    <name>A0A8K1CR05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR05"/>
    <dbReference type="OrthoDB" id="77741at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW67945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="40913" checksum="0BC1559BA0BE81D0" modified="2022-08-03" version="1">MTKVELVCGLVGDVRSVFVVEIDKEKRVGTLIARTKGICGIGADVDLHIFSTQSNGWLKAADVAAYLEKGTINDSMGAVLKSGKLGEWVPIERAFDGMPTLDVIHALVVLIKRSVDDDIDDRPLKRGVWRDVDMAPLEFIGDMVRLSSTFLEGSGLEPPLGRKDLVLFRREAVDNIWGEIQRSAINLTASVVATGSPGSGKSVASYAFAGGLIDLAQWNVLWIRITHKDSHYSIVQFCYGKKLVSAIPLLSMPYVITALLASFDSRGKTSIVFFDGYAKDVKHKVDEVFIRCRTWRDEDRTQRRLVVVSSIAASFEQVFEGTKPEEDDSPRLLLDLDSVSGVTGLKTKTHGEVARWTMATKCDDVLDVMIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR53</accession>
    <name>A0A8K1CR53_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR53"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="169" mass="19095" checksum="50F9FA22E2A0956F" modified="2022-08-03" version="1">MFSIRYDFPEVELDRSTIAEPFSAAEDELLEFLAMASDSYPMHKVICVEAFELENKHEASTAYSPSLFGCASPSSFVTDVIVVMNLRYLIRQNCYSVYSVMENAGKGSLVLTSHTKSNFSSYGQLYALLLIIDVLLLTLNCLSSLELIQWMTFPKFQDVKSWAEQIEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRU9</accession>
    <name>A0A8K1CRU9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRU9"/>
    <dbReference type="OrthoDB" id="59153at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="START" evidence="6">
        <location>
            <begin position="144"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="273"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="6">
        <location>
            <begin position="504"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="606" mass="68228" checksum="4CA30F36EB7A9603" modified="2022-08-03" version="1">MSTRGFLRRGSIKRTELLSTSSQSSVPSDLPPLSTHDKESLIHQARDAYVDLFHAVQVSRSKGSNGTHLEGVSEETGSTVWMCTTTALYGTIEEVGGLYLCNDSHFSLDFTESKRLYELESPSHSHPLRCTAVRWSKWTGIASVVKDRDFVFLECMDSFQDQTTGFRGWARMTKSIELLSCPPSQNPNGPRRGELLVSGKILRETGEPGVLELITLTHVDIKRAVPAWVRKTVIKSKLNALNLNHVLKLRRVMKDKTPASAQQTLLFRDPRQEVDRRACHGCHDHIPRWTRTQSCRECNKTICQECAVVTYYNASTRELKNRICAECSVLDARQRILQAARELKQRQEEEEATQISKRMELSSVSSVSSVSSVSSVGSTSSYTPTSSNLPPLNERQIEEFVHEAHNAYSELFRAVQVAATKSSSGGTHLEGVSEETGSTVWLCTTTTLYGKLEEVAELYLSSDCHFILDFSQSKRLYELEWPSETHPLRCTALRWSRWTAIASVVTDRDFVYFECMDSFEDQSTGHRGWARVTKSVELDTCPPSEEANGPRRGELLVSGKILRETDHPGVLEFTTLTHVDIKRVVPAWVRKTVLKARKLNALNMNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS03</accession>
    <name>A0A8K1CS03_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS03"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="409" mass="46874" checksum="576284FAB3C73A1E" modified="2022-08-03" version="1">MTTRMHRMRSKDTLRHESENASSVNDQVSNASQLSVLSTSKAPRAPEKDDRLTKKKRIRPPRKATYTIRKEEKQELQEELRVLTARMELIKKRLGVPLDADHDTLEQAQVTQAVMENAVRKQRFALSSLQSLLSSHLNSGAPNPLKLPIRLTKDMKARRETLTALHRKQLDLSHEFVSKRLEHIDITKPYNVEERYLSDSGDFHFARFEILHFENVDSVKQVFDALVLSKFNLEITISANLGHFTVREDVDDVDTRIFNYRLVSSFHTGIIQEMNVVNFAAYYDSFVDCGGQPYGLVIASSVDEDELHPYCPDERVRKDVTAALALTSFRRPRQSRSSPSSPCSSVSSSEDSDGELVVVMKRCSFLKIHRPQFEISDRTWEELQLNSAKWADLITKSVRDQLLVQQTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CST2</accession>
    <name>A0A8K1CST2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IQ motif and ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CST2"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037695">
        <property type="entry name" value="IQUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057887">
        <property type="entry name" value="IQUB_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074:SF0">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25805">
        <property type="entry name" value="IQUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IQ motif and ubiquitin-like" evidence="2">
        <location>
            <begin position="382"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="517" mass="59695" checksum="6A6071ACA57564D3" modified="2022-08-03" version="1">MPSSVADDEKQDDVETEEADNNNSNHMAGLFRSPSASEVIEPDPATSFSGEFSLLVVLLPDGVRHRVLVSPEYTVAMLTDAICLDLRLNPDLISYPDLNPAPGLLLTETTLGALGYDGVDPDAHTVYVNVARRVSNSDYVMPDRIQVQVFDENTQAYRSIAVDIEKFTGHKPYLGGFRHRKTQQIFHHASSQTVLTRARRSYGPRSHRNTQTQELTTRSVQTTRESGTQMERRDLRMDNGRDRTVTAKPYFDSYQFHCLKEDSVLLIQRLWRGYKARSYVHNLCVEKQRMATQHRLDAEHMSFSDVEHQKREVQRRMHPKTVSDFEVLYNELDKWRQIETRKLNEDRTLDDLARQDALEAILAKETKLLQTIDRLKLTATDANRKQRIESMLQFMARPKQWQMSDGGVREVHTPFTIRAKELADLYHGLKMSLISVDERLDVLLHAKWTVKEFECPLTREIIELIDREADMLNRGRKEKSLEGLRKRLNNLFLQFIETPEFNPEAVVLKQTQGTNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTF4</accession>
    <name>A0A8K1CTF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001763</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTF4"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035436190" description="subtilisin" evidence="10">
        <location>
            <begin position="21"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="174"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="462"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="463"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="545" mass="57004" checksum="2BDD05D6F665BFA1" modified="2022-08-03" version="1">MVSTKFALIAAALAISRASAAPRVDPAVHRTLRQQGTVNLIITMKDSNTEPLKVVQEASYATRGAKIEALVERLSAHATTSQADVDAVVAHESSASLFAKTRTFWVSNQRYIEGASAELLEKLSAVSSIFEIREEQVLPLPKFTRANTTASVQANEWGVTKVNAPTVWANGNKGEGIVVSTIDTGVLGTHEILKDNFRSDFGWYDPEKQASAPYDEQGHGSHTMGTIAGANGVGVAPGATWIACKGCRTDGCSESDLLACAEFITCPTDTSGKNKDCSKAPHLVSNSWGGGQGDTFYKSAVDAWQAAGIVPIFANGNEGPACTTSSSPGDYENVIAVGATDSSDALASFSSKGPSTGGLLKPEVSAPGVNVRSAWYTGNSDYDTISGTSMATPHVSGVVALLLAAKGDLTYAQVKDALINGVDTSTLAKSGYSCGTSNNKDGVFPNNMYGYGRVNAVKVIDGSSATPTPTSSTPAPTTKTPSPTTKTPAPTTKTPSPTTKTPSPTTKTPAPTTQAPSSCGDYDYYSCYKADVCYWSWSQNKCVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTG0</accession>
    <name>A0A8K1CTG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTG0"/>
    <dbReference type="OrthoDB" id="10630182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="247" mass="27738" checksum="D4DA764236E1F4D9" modified="2022-08-03" version="1">MKRLLDDVQAYVSHLSNAAVSPRKVVVFKPPELSNTRTSPHQPSHRATTVLSPRAIRSMAAEASATSLSPRIPPKRPKKIIQLSDHEESILELALFYEEAMKQMTGAQQKKKNMHFWTERWLLVPSRTKTKVLKSVKAKLSRGSFFSNAVGRESTPQRSQSSSSTVRLPDRSQLKHDTLFSIVVLCLQESIRSVSVLSSDAANSAWQVLCEDTLKRVEGTLDLVMEQRGKLQDQLEEMKNSRASVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTK4</accession>
    <name>A0A8K1CTK4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTK4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035457511" evidence="1">
        <location>
            <begin position="23"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="113" mass="12379" checksum="DF89C055AB7FEBF0" modified="2022-08-03" version="1">MIFTKFAPLVLASALVVSAAVAEPAVQRTLRQAAADDQAPAAKVAATKACSELEWYECGLTPECGYYWLERKCLDTSKTPVPFIPCDGLPWFDCTMVGHCNYSWTVLKCLDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTZ1</accession>
    <name>A0A8K1CTZ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTZ1"/>
    <dbReference type="OrthoDB" id="61797at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025204">
        <property type="entry name" value="CENP-L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13092">
        <property type="entry name" value="CENP-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="463" mass="52013" checksum="C2F361ED346DED8F" modified="2022-08-03" version="1">MDRDLRSPPRHQRSPSMATRTPSQPMMSREPVRARHASTAAAPSQYGGFVTPRGPRAMWGNDAEPVQTRGGMPRKASSVSSMQFDPSSQPYYGEQGRMPAPVAVRVPPPVMRAPPSPSQDEGMRVEDVLLDKRWTLHVVSHLYYFHRRDLSAYAQDLVTYLRDRSLTTYNQEYGYNVSIRYTRNLVTFQVSEARDLEAEALLEKLEQPVRPGHPQQPQPNVANDVEVKHRKGALILYFPEGKQDPPTDGSAYPVVQRSAMGPGREQHHALLVRGTEELMVSVCSWLQQKFQCLVDRHLVRMNSESLRRVTRAAIQELLEREGRAHQSWMEANAANPGAAGESPALSSRGPLRLAYSSVIPAELVRSFALTVPWMTVRRQGMARARPDEATDLVERLEQSYFANLAENLSTMELTGVELDEVHISTQGTLTFYKPSLVLFTLQSILDLMTTQQVRAPVRAATTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU18</accession>
    <name>A0A8K1CU18_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_001400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU18"/>
    <dbReference type="OrthoDB" id="46760at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW69244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35417" checksum="0EC4445E34676EC4" modified="2022-08-03" version="1">MSHTGVILESRERNLVAKGFRKRIAFFHACARNSLDEVRLLLAHGADVNAIGEEGKTPLLSACKESYRLSIIRLLLAHGADVNAKDQNGVSPLHLSVYQNIEVVRELLSCRADANAVDIVLLDEQHFTTLDNLGTLKMVEELLAHGAHVNAVDKDGNTVLRTACEYSRIQLITTLLRVGVDPYHADQDGNTLLHLAALKHRNFVLTVLLRHGLDANVRNRDGLTPLAVCLQWGNDATMVEVLESVYQLMGKSAIYDDSMARIFSEGLTDRAHVETIRSCAEHWKLEQRRGKTLLTKVPYKVFWQGASAVKDYFSSLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU48</accession>
    <name>A0A8K1CU48_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_005786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU48"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="820"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="877"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="877"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1112" mass="122282" checksum="D9F93AC1937311C0" modified="2022-08-03" version="1">MRYYGLDAGLPAKAALRIRQAPHGDADVCGRISKGHVIAVCAPEFQVPSEDDETLLQKWLHVVCPDDSLEEMVEGYVMASLPDGMTLMAPWEDTDFLSCCRVLNEHALLYDSPLNNAEVVGRIDAGEGVRFPFGVLAVDGSRVQIYHDEYGTVWVDAVEIEVICEMLEHPKCKARHSFFTLNEQLPSEAQIAIRSFPSKEAETVTLLSRGDVIEAELRSEKWLQLAEPAGCWIMLQSGSWDLLTEIPYHKTDRCEATQSISNNPLNDAPMGDNQVRVDSKDTFDIQQELDMNQQCSSPIPNDRSSTEDEQFEDTVDDMPIADDPAEASSNYAVNTEASNYTHAGSLTSGHWEADATKENTSPESETAFQPITQSDGSPAYWNAAMAGNAEGTADTDPSYDSSMLEEDSDAQATDEEMCVVEETGEISLSLHARPIDASFDDDVSELQPGEVMENISTIESGMDDSEVETGDEGMYVVEETGEIIFAQQMETSYEEESSICVVEETGELSVIKKTPVAHDVVEEEGENSEGEVVEPTVAEFMTQKLHELEPDRVGYGLFRAIASDADADTILENLVMEHSEDASWLKYEPPALRNQELHQPENNLLDVLYSRENGEPPRTPTKNTPSSPGASGVLTTPPSHKDRLNDICSRTPIREGNAGAFNLIMSNAAPEKILGMEFGSHRDELGLFGGYQYPVLSSSNYQGSFKQPAASTFIGGRVRGNSGSGFAEASFASPDAKLKTNPLKRCARVVSFRIIQGMTGTDKGIDAYDSDTAPSAVHALKERAPRQRRQKRTDHPVEMTAVTDQGQAEEEEDDEPMDCLSVVMIAIVIGLFVGFFGFLYVQMTTQSDIISRRLQNAPKAEPKHLSLQVTLAQLYNGRVATVDVDRQLVCRHCAGSGMDLKAGFHTCHACQGSGVRTVTQQIGPFQQQMRTTCSVCKGRGKIANQMCDVCHGHGSLRDRKTLSVTIERGMKHGDTIVVPKEGDQSVHVLPGDVVVHLTMSPHKLFTRRGDDLETELKISLLDALVGFTTELTHLDGRTVRLSRTAVVAPTDVWRIPDEGMPVRTTNVSSKRSTNAFGDLLIRFAIQFPNKLSHDEKHGTILLLFPTECRSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUH4</accession>
    <name>A0A8K1CUH4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUH4"/>
    <dbReference type="OrthoDB" id="10265695at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="56"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="41253" checksum="B8ACD5671350A0A0" modified="2022-08-03" version="1">MSVWGQPLGVPKTAPSKPAAAAPAASNGTTAKVTKVKFDVTEAIDIFEGVEPVEAVEIEGVALLQIIKHCHENQPKSVAGSLLGMENGKVLEVTNSFPSPPSSERKKESDEYQMEMMKNLREVGMDNNKIGWYQSVVMGTFSTSSVIQYQFQYQQSLGPNAICLIYDSSETAKGTLSLKAFRLKKSFVDAYKAGVFTKESFAKDDIRSTTVLEELPIKIHNADIINCWLHEVVQKNESVSTNTFERLDLATNAYLENSLKNIGLWADELAQEHFKFQGYERALAKQRAAYQQWQARQREENKALRENGEPLLPEEDPEFFKSVHQPSRLEALLITKQMNTYCEHINRYAGKSFQKLFLASKFHKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV23</accession>
    <name>A0A8K1CV23_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV23"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="18"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="36253" checksum="D1B5F3884EB21FD6" modified="2022-08-03" version="1">MAAAVPATYRAFQYVEHGVTEDKLFVNNQTTQETLSNTQVRIRVHSASVNPVDWKILEWTGAMFGLRLLPTKEEPFGIGFDTAGIIVEVGADVKTLKVGDAVYSMTPLGKFGSIRDYVTIEEEYVAPKPAGLSFDEAASLPLAALTSWSVLAQYAKVQKGERVLILGGSGGTGTLGIQLAKALGAYVIATTSARNVELVKSLGANEVIDYTTQKWGDVVDAHSIDVLYDCGVEPASWNYDAQRVLKHNTGRFITTFPPDEPIIDSPIGATYEHIINEASGEGLRRITEFVEKKQLVPVIDSVYPFEQTVDALAELKKGHARGKIVIQISNDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CVS7</accession>
    <name>A0A8K1CVS7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CVS7"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="18"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="333" mass="36324" checksum="816CB959A1C9202D" modified="2022-08-03" version="1">MVASVPATYRAFQYVEFGITEDKLFVNNQTTQETLSNTQVRIRVHSASVNPVDWKILEWTGAMFGLRLLPTKEEPFGIGFDTAGIIVEVGADVKTLTVGDAVYSMTPLGKFGSIRDYVTIEEEYVAPKPASLSFDEAASLPLAALTSWSVLAQYAKVQKGERVLILGGSGGTGTLGIQLAKALGAYVIATTSARNVELVKSLGANEVIDYTTQKWGDVVDAHSIDVLYDCGVEPASWNYDAQRVLKHNTGRFITTFPPDEPIIDSPIGATYEHIINEASGEGLRRITEFVEKKQLVPVIDSVYPFEQTVDALAELKKGHARGKIVIQISNDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1F9H3</accession>
    <name>A0A8K1F9H3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase SHPRH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46533at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048686">
        <property type="entry name" value="SHPRH_helical_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21325">
        <property type="entry name" value="SHPRH_helical-1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="1389"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1479"/>
            <end position="1642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1783" mass="202074" checksum="96DA3AD0BC82BBAD" modified="2022-08-03" version="1">MGRRKPTHVQRHFQRARAEEKEEARQEDAGDADEGFGGSLVVIDDSEEEEEADGDDEPVRRAPVLKRARAGAPIDTTYRLAFRQLSLLWPGNASWSSDERQHALWIAFPVASESYLHKKLQELVKNQAQSSSEAVVIGFEHEDHGQKKRKGAKSVVVEERELFSLSPSVHGSLTDLIRRNLLTMEVEYLPGTMDEDATAFQWRFGVNWRRYMKICSKQKAIHWTPAPNRNGVVKDMRDIMLWLLYQSRDPLIRSWEYPYEKEIKALYQRFVAREESLDDMEPREFDVHDVYTQINAHEQLQRDTSNIPEQLTKDGLLLPTLREYQKAALSWMLEREGAREPGSLTEDVVSPCAKFKQPELVSPLMYDVFSGRFTSLDLDDVSPISEQKVIHGGILADEMGLGKTVEVISLVLSHPAPSSIPALCAPLSIDPVSDRDTVFDKRRAHCICGSDEDNETGWMQCDACDTWHHQLCTGYDPKNPPTVDSAGTVGAKTEYFLCFHCQLQIHPTVACKTTLIVSPESIHDQWETELKRHVKPDTLRLLRYPGVKALRSRLDGRGPSAGWQILSNLGLEMAKYDIVLTTYEALASDLHHLPTDAGKERRSSTRQKRKKYAFVASPLVYLNFWRVCMDEAQVGVENTQLQAALTVAQLRTTNKWVVTGTPFSTQLGDLYGCCKFLGVSPFCDDNGDGQVYFREIVERCFPIGAIDRVFDMLLWDGRTQTADGRKIANGGGLLWRTNKRDVLAQLDLPTQLQEVIWCRFSEVERHFYDQQENTLIELLTEQQERREQMRDGDGESEVSEGVWHHLLQLRQICCHPQVGQTMSAVYSRGGNRRRARGSRGLRRQQAVNPSLINPLTGPGASTGTALITMEDFLKELIEKCRRECEEAQRKLIGAHNGLAALALIEDDTSTAIIKYLVCIKLIRDNWKECRADLLPRLHVLENAAKCVRQTFGLVQQEEGSASNDGSLQADVISTEWEDFSPKQASLMPNLVALLASISLENEGALDVEHSDLIRIHDECRSMEAAAQRIRSFYLGQVEMAHSSALVKFNEHRNTLESKLCGARDGRDAMLCGETAWWADTIQFLIRFGDQQRVFNIVDRLRARLLSFGSNWATDFERRFRDIHGLSLALVHEFVALRKMRSSVFTKLEEMSSDSPSRDDIELSGNCRKCRDARDGPICKHCRYYKELEGYRQHFLGVDTLTTSTGGAMRGVTAMQMYMDEEHEEGSTMSTSTTASTSLVLELLRELATATRGILRDRRDHASRQLLQAIQDGVQQEAEVWTQLTREWTSAKKLFQAQHQRLGALDELEMACMQLRLRHQHETIANATDRLYKLEAYEIPLKKQELEVEQAISSRELQQKQSQLRYLLNMGSRSNTTTSTGDSDDAQDPCVVCLEDMKDEYAVLPCAHSLCKSCVDALANRNRSTQSIRCPTCRRVCSPSERRIVHRLSSVQRQSKSRNTSQVPLADGDITLTRGGFSTKIDAILRRVLSLAGQGTSPLKALIFTQWQDMMAIIAETLQLNGIQSFTYTSKKQFPRVLQQFKLNADPCVLVLPFKIGSNGLNIIEATEVLLIEPLLNTSIEAQAVNRVHRIGQTKQTRVHRFVIDSSVEERIRWLSKEQKKLEQVEAVRGRADGVVEEEKDEDNDDEEEEETLVVGRKEREKVTITQVHQLLLKGREDPSSRGEHPFWTENVVLNGRNMSRREAHEVLTRRHAAEARREGSEAPPIPYTRLVNEDVNLLIARELLTLPAAPGAAQDEDLVAMLHSRVETMHRTWQAASQQAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAV0</accession>
    <name>A0A8K1FAV0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAV0"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="493" mass="55430" checksum="2F3425B6CE4DBE69" modified="2022-08-03" version="1">MAGERTPLFHSDANVRGTKRQKSLYRITLVVLVSATVGVVLYAISNRYSTSSTESAKLSSLLNATENDWFCNEPSFEASYIKLANKKDDYYFYWFAASRNDPSSDPLVLWLTGGPGGSSMLAMLTENGPCMVKPDVSTERNVYSWSNNANVIWLDQPTGVGFSYDGGSDDDDYTELDVGANIYAFLQGFLDKHPEFEGRDFYITGESYGGHYVPGASHYIWQQNKASGDKRINLQGIAIGNGLTNPLVQYKYNQDMVNNQYNISLLTEEQAAQMKTDSEECIELTKLCQIAPNNDTVCVDAPACWGEKLIMPFYSARRNLYDIRQPCSGDTPESCGLQTSYLDEWFATEPVAQYLNFTTKRWIELNDTVDRAIVDSGDWSFSYHEYVADLLNDGLRVLIYAGDADLMCNWIGNRAWTLELDWKNKEGFNAAEEHAFVAVDPFVDGASKVDAGVARQYKNFAFIRLYESGHMVPTDQPAVSWVMIDKFFNDGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC55</accession>
    <name>A0A8K1FC55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Coiled-coil domain-containing protein 104</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_013419</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CFAP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC55"/>
    <dbReference type="OrthoDB" id="272687at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038888">
        <property type="entry name" value="CFAP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21532">
        <property type="entry name" value="PHOSPHODIESTERASE HL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BART" evidence="11">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="167" mass="19402" checksum="627FE8B62E0B26C5" modified="2022-08-03" version="1">MADDKSIQDPVVKALAEHICSFQFQRSFEEFFLKHALSFTDEQEHQLDYMTIYLEFQQLFNRQMEDFLTAQGISEDEFSRICQKAIKQDKRADNFLEIVIASMDYDAFFSLMKAMRGRASAERKSKLGHGDDDEDDKDSDAKGTSREAKHSDEKNDDDEKSEDKDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCZ0</accession>
    <name>A0A8K1FCZ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006349</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
            <location evidence="1 6">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCZ0"/>
    <dbReference type="OrthoDB" id="78652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF27">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="3"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="619"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="844" mass="96226" checksum="A2571967E693119D" modified="2022-08-03" version="1">MHHELFFALLGHAGDVIEAKSDGFFIRRDVSFLSAPQKAMIDRLLQLGHAFATLERFVADARHLPSLYLRGLAQGVERVLGEYTDAIVALEAKILTTRVVFPIPQMMYELEEYVELLPELCKLVRRIRATRGESPCLRGAPLLELLHRMMASGFPRLRRRIQELLHCCHRILFKQIVSWVLYADVLDPFDEFFVKSHDDTASSASVESQIWQSRFRLDLEAVPLSYFPIAVADSILFIGKSIQILARANGFAPTESQQIVTEFMHLTATHEFSTVALEQVVEKTRRHVAGRLYQEVVVKSDFVDRLRVLKDMFLLSHGELFQALIDRTSTIMTAKPSFKSEDELHHSIWSQILHDFHLDDASWTKPFSFRIPLQCFHFPSFITTEGLALLNVRRDAEAKSLEIKDPTQVCGTTWWRHAQLEHLPFTSECVLSGVRTSNKPQRVALFVSTDSTLPEPHLSTGGGFVIASVHIKSIMIECVLRSLPEAPLCAGVSCRVVSFRQGDQEELLLPPETVVETRDGACHVYVQHARVEERDAKGAVKTTRVLLIKVNDTLVMEAPFELKVMFDGDKKITTPYYLGLGWTSPLAVQQWTVDKFPHKAVARQPGQNLKPINQTILPRDLWNYLSLQCELEWPLQLLVSPKLLESYNLLFQFCLRLKRVAYALERTWKCEVLRTMEADQTARAASTLRGRMSFVLRNIELYFQVFVVEGCFSKCLADIEAAEDYDRVKRIHENLVGQLINRFFLGVALASSALDDVMSCCWDFAEFVLDAEHHGVKVLASDRIGDLGKQFTTSFDKLFSILERMDARDFLLLLDYNEHFSQIARAKEPKTLRSASSSRIFHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FD55</accession>
    <name>A0A8K1FD55_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68488at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="749"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1160"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1427" mass="163869" checksum="F6E71E9A5BAC0997" modified="2022-08-03" version="1">MPQIHAVHEAHQGPDNIVSIRDAHSNELHAVSVPHSDISQCVRFSYLRCLLSFLSILLVISDIPRTGFNLDLKAYYPVLAPGIITYYGPYDYPVSHIVRDNASSYRGESGGVQINETRVWSYKYDSVSIGLRGLVQLLGVQNLFLPCLLYEEECETETLELETVFTMLDKLFNALEIRYFHNEAQLPVVFQATSNWIDRLHHVLGRSVKPRVEKRLHTIHRYSGSVVSVCAPDSRRPDALCDTAMPWRCQHPIDPTKDTVSVAEHVDLRFAALQDRYPTLQLELFVFSARLRTQNSAYLVLPSVRYASDTWEFITFIRGRACATCETVFLDEYRYERSILESDASEWTWCLQFLRGAGQVYVWLRVMFAVWGCFHAQLNLLWSWKKCFLVTFTTFFKIPSHVIVYSSWFPVVCYSLAHLIDCGLVHLISDNVWSSLNGFVQFNLLSYVLVASIQMRNVWILALFWKSLLWIHTLVNPRAQHWRPAMGILGIRGIFLTFASWLTIFSFMRAVRFRNTDILSVDELPRHSTFGDVQLGLKFINHSEFGLALDVKTTLITTVIVGLNVFFVQSTLRLLTQHSTHFLFCRSFFVPLSAGTLFPASMLNVFWFLPRQSTHHQYLTARETLRTILLSQQIHRKVIRPRPKACEACSPTMTALHWRQIQGCSRHDALDRIDKRPIALWSVVCLVNLGHDDIVSIHDAHSGELHAVSVPRSNISQYIRFSYVRCVLSLFSILLVVSDIPRTGFSLDLQTYFPVLAPGIFAYYGPYDYPVAHIVRDNASLYRGVMGDEEIDETSVWTYKYDTVSIPLRALAKYLHIPAFPPCILYKNECATESLGLDAIFTMLDALLHEIDKRYFSTKTNLPVVFHVTNNWIDRLHHILGRPLSSRVEKRLHTVHRYSGREVSVCSPSPQRPYLLCDDGMSWRCQHPTNTSKGHVPINEHIDLRFLALQQQHPTLELDLYVFTTRLRAQSYAFPILPTVFYESQSSEVIALVRGRACAACDTVFLDEYRYERATLETDANEWTWCLRLLRGAGQLYVWMRVFFAWWGCFHAESSADWKTRCRVAFTTFFKIPSHIIVYGSWFPVVCYALAHFIDCGVVHLVSDNVWNSLNGFVQFNLLSYVLVASVQMRNVWFISLFWKCVLWAHTRLNPRAQRWRPALGILGIRGIFITFASWLTIFSFVRAIRFRDTNVLSVTMLPRHTPLDDVQTVTAFLTYSEFGFLLDIKTTLITSTIVAASVCLAQSFVRLVTQHSTQFLFCRSFFVPLSAGTLFPASMLNVFWYLPRHSTQRPYMTVRETLHAILVAHKTRRNVATPRSKVCETCSPMMTVLHWRHTQGCEHHDALELVEVRSTALWSVVCLVNVGMLSDPLVVFDLYVLGRSLAIVQVGDSLLVLPWEASNSSEHRSFRFVGLAHSNDLPWRVLVHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDW4</accession>
    <name>A0A8K1FDW4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-ubiquinone reductase complex 1 MLRQ subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDW4"/>
    <dbReference type="OrthoDB" id="154060at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="12411" checksum="88DDB65B25F2EC0D" modified="2022-08-03" version="1">MVAARATRSGISLLKLWTTDKGTFPIVLIAAGAATAASVVATRYLFFNPDVYFDKERRFAHMHHDGDVGSRWRQFRFRFANYDRNPINQSRQYDPLYEKPENQAVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP0</accession>
    <name>A0A8K1FEP0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP0"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34574" checksum="2C79CEA726B616B9" modified="2022-08-03" version="1">MTTERIVKLFAHGGGLSQETWKPIIRRVMTAPLLQRVKSEVVTFDWRYHGANHRLQEPGTVHYLNGDEGSPRVSHTAREWTHWAPRDLHDIVKTLRREDSALARRTRIVGIGHSMGACSIINLEIAYPGTFDGIIAFEPVCNEDTLPGDPKAFVSKMVANTLQREHTWDSWDDVATHFKSFKAYRRWHDEAVDAYLEGCVVQTEDGKFRLACDPVQEASLYCHDIMKFTVEDHSRLGCKVVYEHGEITPLFNAEATAIVVKALPDKVFLSSAMKGVGHMMVLEDPVACAERIIQDLEVSPVFQHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF99</accession>
    <name>A0A8K1FF99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF99"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="497"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="82901" checksum="A35D5C8953FC0FD6" modified="2022-08-03" version="1">MHASTQRLALLRRSTTRSLLHHASQQHLRLLSSATAVSASSAASWEPQKRWKSTRVSVDHDDEGPVQHGNLLERAADAADEEKTVWRHRPQRYTSISFRDMDKQHWKHMDRTKFRLLLEDCMAKGTVTSMLRRYLDEFPIMDIRWSDQELVLITGALIKSNRDKLALDVLQNQITEANLNRLNRVAAESARLGNARVAIGVLDIAKHFQMAPDVITYTSAIHACARGPTDDITQAFELLDEMLVANVQPNHRTYGAVVLAYARMNQWDDIDALMDSIPYDKEVLPMSEVYTAAIISCTRNRQFVYATRLFQKLMNQDLYLGEKVTNAALSACARTSDLETLQDILAFTEKHAMPSIYTYNTMISAYGHARQMESALNVFDRMQENNVKPDLVTYNALLLAACRSRQDDVVDEILNRMQDQKVRWDVYTLNSLLEICQQTGDTTRAKGFWERAKKEQRLRLDRANYETLLGVHYEAGEYETVINIWKNSMPCRRRAKSAKTLNFLIRSCAKLGEVETATSLLEEFAQRGQIATAIAHNHLLTAYLTSDDWLGAKKQLQAMQTDPKLSTTLGFTSLMKHALKSEQYGRVLDIYEWYQDQLVAFQNSWCPQLRFPADAVYVYAARAAAELDDHERLIHLYQSLPSPATSASVRAEIARLVLKSCEKHEDWRHAVSLYDEVSKIVDEDTNVEFYEIVVKVVARAGEFESALDVNGGEWYRQNRPDQGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FG63</accession>
    <name>A0A8K1FG63_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Necrosis inducing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FG63"/>
    <dbReference type="OrthoDB" id="147163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445981" description="Necrosis inducing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW58382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28565" checksum="BDD3FA50E300C1A7" modified="2022-08-03" version="1">MKWAALLVFSAALLSTVRGDDFPKLDAAPPKNIDISSITPVLDMDTDSCLPSAAISRSGQQNGGLKPTGKITGGCRRGDFMDFSNTYHRYACVNGNGNQYCGHFFAYYFLKDQAVPTFGGGHRHDLEQIGIWTVNGRVTHGGFSAHGKMENRPVDQIPQEGGRLKFVYHKDGVVTHAIRFGKTNEGAENPTGAFVVPTLVSWFTMKGDTIDNAGLRNNLNSFDYGNANMPIKDNNFLSNLNKFRPSDFPEFTQESIDTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH88</accession>
    <name>A0A8K1FH88_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH88"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="6">
        <location>
            <begin position="336"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="581" mass="65693" checksum="D4CFBDC331C78D00" modified="2022-08-03" version="1">MASSTAEIKQLEIKIKEDVKQVNELPKIVKALKNKDKAVAQAAMLSMRRLLVFFAEKGDLKATTTAAPSDAKKQKTDDAVATFRKWLWGIYVSFIKEMLDWLLKGQDENVQVNALRTLMEFISREGELRGHGAPAFGNETFMRVVQQLMANPKLKGEVASVFKGEYVGAYLDVQYYMLRNLTQILDTELEAKKEPTGDFTFVSNALRLLNMVNMPAKAEDISSFLVEVKTSDNNDEEDDDEEEEESEKEDAAAASVGAKRKATDDPKAAKGGLRSLKQHQHVFSMCWVAMLRHQLPQDAYKKILTQLPFEIMPHLENPLLLSDFLTDSYNLGGVTSLLALNGLFILITDHNFDYPDFYNKLYNLIADPTLLSAKQRFRFFGLLELFLSSSHLPAYMVAAFAKRLARISLVAEPGAILFIIPMVYNLILRHKECLQLIHRSGATTASEVAKKRREELSSTNSVDAAAKKLARTTTEIALKDGHDPYLSEEKDPQKCNALQSSLWEIYTMRYHANAEVALKAKMFEEKLRSQFLDLDESMDITYKSMFDQQLKRKAKGRVPLAFKPCTTLFTEEDGFANVFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHE0</accession>
    <name>A0A8K1FHE0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHE0"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF34">
        <property type="entry name" value="PEPTIDASE S54 RHOMBOID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="6">
        <location>
            <begin position="237"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="38631" checksum="15F9AC812C84A1E1" modified="2022-08-03" version="1">MLVMRPLTTRVRSVCMSQRASHVRTSAWVYRESRGDAAVRFAASGGRWKGQYDRVLLASLGLVGGGVATTALYKRRELEKAVETVCYRGEEDDTWSGHLQSSARTLKRQADAELQDDNRKVLVGIIAANTLVCGLWRLSFRYPTMQRLMWRHFACSYNAVVHGKRFHTLFTSAFSHITIPHIAINMFMLWEFGHHILAPKDNKDAWLDKALARSRTVEYFRSSYVNTINSQLLPLDKFLTLYVSSALSSSALSILMSRVRGNPGTFTLGASGAVMGVLTMYCLLFPDRQLMLYGFIDMTAAQMLQAMTAFNLIGSAFQRGLQIDCTGHLGGQATGLAMHQIERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHG2</accession>
    <name>A0A8K1FHG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000048">
        <property type="protein sequence ID" value="TMW63870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHG2"/>
    <dbReference type="OrthoDB" id="93167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635:SF196">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="251"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="56545" checksum="CA9D0E4267D9916A" modified="2022-08-03" version="1">MPPWVIDLPEAQEHLKTSLNALADKIKYSDDYSFNPGCLLDETKRLDSIFLRQLFTEKKNQQHGKIERLHLEINRLRVANNVQASQDTEEVLQARIEELKALQEEQDFFASKKKFAVDLEQSEKCSKYFLRPPQLLHKSRIPVDDEDDLHDTSKAFNEKWSRVYCSPSREFNHPRPQWNKDKLVEILQHSTKKITDSQKDYLESPITANEIYWAIKTMAPDRAPGPDGLPLAYYKTDIHLWSQVLECVYAAQFALGRMTKFQRRGQIILLYKKGDKRDPLNHRPITLLNMDAKIPPKVLARRMGPALQTILGEDQYGFVPSRDIRNAHLRFQALQQLYKKKNTTAGAVLLDFAKAFDSVVWDALDLTLTHFGFGENFCEWVKTFFKDSLVSILFNGDPLPSFQIGAGVRQGDPLSPALFVIYIEPLLNLLRATMKDKGLRSAPQDPSHTVISFADDVTGLLHDLKDAPAFLEVVNEFCEASGMKLNTDKTTAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHY8</accession>
    <name>A0A8K1FHY8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_000284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHY8"/>
    <dbReference type="OrthoDB" id="115600at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW60242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="504" mass="55357" checksum="A7B25DA2B228EBA6" modified="2022-08-03" version="1">MVMMMSSPMMLGRARLLQTKAAGATIRRATIYLGRATAVDTATFVERAESSQSGAKLRLGGEDSHVTVTRRGVGSPYLWAKDMPRIESSKKAVTGYQSNFLQASINPYTDAPANPEDKQSYVESLVLQEVIEDEGFPREALVVSSILEDSLVQPANAGPTERLTAEYIEKGLKIALDELKVEALDQLVVRIPDELVQSHSLRSKLNDTLARTADILESLCASKKIGSYGFALPASHSSSSILEQLLSTTFLTLSEKHSNFSALQLAMPLSTSITPLSPALNEFKTSRDMLIVADKVFEASLSNGKPLGIRSHTSHLGEDVALLLKSAFNLAISIERKYMETIRPENSELALPAVEDVAWAHILANQHSQFDNLEEWIYIRETQIFPRFEVTVKQFEAVEDLKEFGFAYSMALRELLKCFTASVELLDASRTDSMLAALNENNLLVSPEERLEHIAVKAALSAGADAVLTQEQLGKDSTLAFEAAYSPEYLERLAACIRPALVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI16</accession>
    <name>A0A8K1FI16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI16"/>
    <dbReference type="OrthoDB" id="260824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21150">
        <property type="entry name" value="PUA_NSun6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF34">
        <property type="entry name" value="TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="143"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="245"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="476" mass="52718" checksum="EE493B17ACFBAFDA" modified="2022-08-03" version="1">MYVSGSDFDAFGVAFPDAVERDFCEAYGEERWKKIKHALAIPPRYTAVRVNTMRTTRDEALVALQRELEPFNEKLVNETGREPVTPFKHDKLNDVLVIPSAPPVTPAVQYREDWKSIIVDRLCGEAVLRGSDIFARGIMSASSGINTEDRVNIFVDLDHLSTRGSDTIEHKGRKLLIAHGVMKMARAEMFRAQRGLAVSSITRVCPDAPPMNGVLSGDIYVQNLPSTVVAHALDPQEGEVIIDMCSAPGGKTSHVATLMKNKGILVACDRSKRKAIELKKLFTEQLPFDIVTPLRLDSMHSVLPKSDATPLSVREVLDQAKASTPKDSHLLQVAGFYPETFDKVLLDPPCSALGLRPRLLHAGEEDDLAIFTSMQRNFIWSAVYLLKPGGTLVYSTCTINPKENERMVRYALDNFPLRLEPQPIHVGDTGLTNQGLTEAEAALVQRFDPSNETLDTMGFFCAKFTKTASIRKEPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIC6</accession>
    <name>A0A8K1FIC6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004677</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIC6"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178:SF41">
        <property type="entry name" value="ANKYRIN-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178">
        <property type="entry name" value="MOLTING PROTEIN MLT-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="140"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="182"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="497"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="597"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="630"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="70393" checksum="402545943F659E6A" modified="2022-08-03" version="1">MHVLQGWPAICYVATHNDNADALKTLLRNGAGINVKTEDGSTALLLALSRDWDCDSKVDVLLEYGVNVDVSTEEGYNAVYLAAKFRAVGALKKLLDHGVNAGAAANDGSTALHIAAEKGNNEALELLVEHGVDVNAVDRDGRTALHLPMLAEIIRSTYGVGFAPTVKLLVNHGVDVHMADVNGCTALHYAAKCNDGDMIATLLEHGAAVNAVTNEGSTPLLYAAFCSPWIAQDLLAYDADVTAVNKDGFTALHFAVQQSNDVLVKALLERGADMHAKNAAGRTPLDLCAKRDLHSYYVKDTLTIVYALMSRWASLGSTWEMQASVSEEEEQESFKSVGWQQPRPPSIKRKDHHSVGSVCVSRGHFSMTMETELHTATTDGDVDRVLSLLRRGAEFTALQQAAACGHVDTVEALLTHVVAVNAVNRVCRLYMWQPALVTDPIQESYRRDRDTSTTRGRCECCGAARRYGIASRVSNWSVEMVRVLLAHDVDANLTNDAGDTPLLVACQYLQLRAVTVLLTHGVDVNIANKRGATAVIVASAIFHQADMMERLLEHGADISGWRAVTALFSASGLGASASVLKVLLAHGVDGNTLIESTGRTALHCAVALGLVDKVKVLIAFNVDINIADKDGLTPLMCATKAGHARIADMLRAHGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJ05</accession>
    <name>A0A8K1FJ05_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000310</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJ05"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01262">
        <property type="entry name" value="PH_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000191">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033931">
        <property type="entry name" value="PDK1-typ_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14593">
        <property type="entry name" value="PH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="503" mass="56970" checksum="9B81D08261BEDFFC" modified="2022-08-03" version="1">MATTPTAGSRTVRTQSNHSDRGGHPSPADFMFGGTLGEGAYARVVHARMKRTGAEYAVKIMEKRFIMKEKKVKFVMMERKILTKVAHERIVKLSYTFHDDNYLYMVMELCRGGELLDVITRHQKMQAARGIKDRACSLELTKFYIAEILLALEYLHNKGMIHRDLKPENILLTESGHVKVTDFGTAKDESEEHRSNTFCGTAEYVSPEVLRDLEASRGCDLWALACMVFQMLVGRPFFRAENEYLTFQQILNHPAEDFKYPDGFPDVARDLIDKILLQEPKDRLGAGTEEEGNGYSALKAHPFFDGIDWETIGQSVAPYKPAITKLPPTSNDGATEDWLLAGAATELQLSSGLGLEPEEMAPPVHVVEVARLRASQPQQLPIARASSMWDRFLLDDELIKLASLISKRKGLFSKKRQLILTSKPRLIYIDPIRMKQKGEIPWSPNLHVNLKSATSFDVVTPKRVYHLTDSVNGSRRWIDAIHAALHHQLDNQHTPYGHRFMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJH7</accession>
    <name>A0A8K1FJH7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_010880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJH7"/>
    <dbReference type="OrthoDB" id="177428at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="52850" checksum="C396228710DD6BDD" modified="2022-08-03" version="1">MGVAAYTDPLSTMNTYPDYGFVEICMSSDCNVQNPSLVLSLDHLGNDVSVDPSTKQVTFGTELSVFDYTYQFAKNIDEVFEPFLTTPAVDDSASPTAIKSTMTLKMCATGCTPRTAESGEMQATASGILKDSIVLELEVLHRVADVNVNPRGFEQYTFPRNGLQVNLNMAISPPASDPSFSLSGFALTFLLAVTDSKAPLTQTSMSQPQGTMYLHRLEFGSDMFMDLPTYGTMDGSAHPITVSAIPLTSVDTANMIQVTLEFGSATSVTAIKYVSCVTPGPSAFAHTLAPTVVTPLKAASGVSVPQNLVFLPRVSFALCLDPICSTSALAIGFRGVGNTDWINLKRFRDSTAFQFADPLQQSLSQYGQAEVYWSSFSAWVPKYKQSLPVKVDPALASAHLNDPRLDVEVAYFLTNGSVSAGSASIAIPVNSVKLTIMISNWYFVSSTDSLKFNLTLSSLTDSLKSVVDFSTSFSSIVKTATTPLEGVFKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJJ8</accession>
    <name>A0A8K1FJJ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrator complex subunit 6-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJJ8"/>
    <dbReference type="OrthoDB" id="9449012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000010">
        <property type="entry name" value="Integrator complex subunit 6 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057413">
        <property type="entry name" value="Beta-barrel_INTS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051113">
        <property type="entry name" value="Integrator_subunit6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957">
        <property type="entry name" value="DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25462">
        <property type="entry name" value="Beta-barrel_INTS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrator complex subunit 6-like beta-barrel" evidence="2">
        <location>
            <begin position="270"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="877" mass="96431" checksum="81F6ED191EA47EAA" modified="2022-08-03" version="1">MLVTFVIDTSASMNQTTSSGMTLLDYAKSAVERFVKRVRDPSRRYQHHFMLVSCGCDNATANAKARAAATADGNAPPPWNGRVRVGWDQSTNKDVFLTELKNLQATELSDVGGSLKQAFELLNQIRLQFNWDNYGLGRSPWNTNVAVCVLLTDAMTLSTMDGMIQDALTIPPSNAVGADLTQEPFRWDQRLFTIALKLSATMNGSVRSQPSIPTDLMALSEATGGMLYLPTSKPAVEQSIDQIISKLKPGAVVKFRCDVNEGESEFPTSRNTISPVPTGKEYSWPIAESFWLDRNSVSLPSREAHPVLVYRRTVEGAIEAATNHMLLDTLKFPADNYVVETSLVPAPPRGQRWLVYVQNSRGDGRLGDPIGFVRANPSGGSSSGTVLVLLPYNFPLLFALLVEAARVYQASGQSINSTTGTWMFQAKAMPSAWRESFSAYLGGVPLYYYAPLKKALRKYNLHDMVPEVQDLGRSYQISNFLNRLREQSITESEANSKINSRANRIDASALPRSAGLPESSPSASPMPNKDSSNSSTDPIVDAVSSMSFQDLLQIHQKSSRSFFTAQPFRQIAPLPTMHVSSLASYAEDNTLKFGPSSRVHEEDDKHQQPIDSMSDYESRLIKKEALRNPLGDPEPDEDTPAGLRRRQLCFNLGNPYKKNASKQVSNVYQGEAADEAAALGGQSPKRQRTRKRPSQLKRDKKQAKRSHRPPSSPSFSSSPGSPSRSPTSVSSGSPVTSSPVYSESGESVMTDSSVGSNYSVKAETAQLLGVPLRDGEATEDGQDKSFVSVVYGVLVENWEAWSNILRLIKARATSRQEEEFIMNALRSMKGGDVVVQTYISQAIKYAQDFKKQELIKQLETLQKQLVSSEDVSLLVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK02</accession>
    <name>A0A8K1FK02_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK02"/>
    <dbReference type="OrthoDB" id="111136at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="176" mass="19665" checksum="F587BAA8A0C7F32E" modified="2022-08-03" version="1">MATTNMAAGSSSNKRMKRRRAESLEDGMQMEVDACSYDYAHDAEDDAEEEARSHKRSMLIRSNLRFLEKVPPIRDYQRDRSGRRGAIDGGDLTGAVMLSALEESFEETSFVTREPPARVAMVMPVPVPIVPVMDNRPDVHASRSPEHGRIRQTPQSSPLRSLQSPPKDDEARPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK50</accession>
    <name>A0A8K1FK50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_008298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK50"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="13950" checksum="C153C6770E54475B" modified="2022-08-03" version="1">MARSRRSSASTTTARKPAPAPAPAKVAAPAPAPAPAQSNGGGMMGGLLGTVAEGMAWGTGTAVARHAVNAAVDSFSGDSKSAPAAQAPVAAAPTPAAQAPGCYNDQKAFLDCLNTSKNDISACQFYLDSLNQCKQQAAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK80</accession>
    <name>A0A8K1FK80_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 62 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK80"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="46414" checksum="294905D27E15AE62" modified="2022-08-03" version="1">MILHLMQKDVPPILDTTQAIALEKSSVESEMPVTTTAEPERITKVKKLNKAQVKTKKPKRGLASSVLHPRTTSMPPRGATPFSLLGYREPIKGGPNVYETTEIIPQHGSDEVDVHYQLRNDAILSSVASDAEDFTLIVVVTNDEKSWGLNRSAHDFFELLDTFTHPKEMTSVTLLTSSMSEFDKLQKLIQGRIQDYTQLSLLYRTDFSVSKVTRENRHDVSLQRVRRRMLTRYRNYALLTTLESWHQHVVWLDSDVIVVPPDLVSKMIEADRDILTPLCKICGKNNRVREYDLNAWAGSRTTPESSSDREDLFPGPLNVTHIRDFQNGADDFIPLDSVGGTMLYVRADVHRQGVLFPHHFVIGSEWTQEGYDGIETEGLCYSAHFLGYRCWGMPHEVIYHAPKDYQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKZ1</accession>
    <name>A0A8K1FKZ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKZ1"/>
    <dbReference type="OrthoDB" id="165983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="60066" checksum="884CC1FF6C74DBE0" modified="2022-08-03" version="1">MESVRHVTACLDRTLRLEEAKIRLSRAKLLLDARVREPASVPSSITLRDGPKFLLDLETKRAVSQLLRRTKLSFEECIRAWRGQSEADPRPNKALRADHLEWLLHGYDQQEVVLSTIRFGVFHEFAPPTSAGCVFHNCKNHKSAGAMHNALVRSIREGQDTGTYLVLDFDAVSHWRGITPSPFGCVPKADADPSLEARVIHDLSFPRGASTNDASVQSDLPPLTYEHVRAIARRILCLKARDPRVEVLMMRGDVKSAFRHLFGHPSVIRRFAGVLQELRVLVLDLALPFGWTGSPAHYGAFGSAVSFLVRRESPATLCPGDADDESFFCYEWVDNHVLVEQAKGDRLALCDIALRLAMVAVLGPRAINEKKFTSWSTQSRALGLDWDTTACTVSMPSDKVEKALGRVRALLAESTATQSSLSQLLGSLRHVSSCFRPAKPFFQRLATLHRQAYRFVTVEISTAARLDLLWFEHILQFGKLQGVPLRFFADLPDPDVHIFMDASDQGLCALDPARREFLRIEFDEEEQVLIRDQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKZ6</accession>
    <name>A0A8K1FKZ6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKZ6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="353" mass="39706" checksum="0B9F3C585D942532" modified="2022-08-03" version="1">MVDRAKSVSVKWNDEHWLGSTKEALVRAADRFPEAELKGVEDKFSRDMAMMDDECEEDAVRSAELMRSELLGVADIGFSVDLIKPSDLHLQAFNSVKEYIDVLTSAQGLSHEVSEGTEMILRLPFRLRNHMKGFFGIYENGETDRLDELVNKIVVAKLTNLKAETSGVWAKVRGLFKGEDESPDLTQFFEYMRVPLDSMKQAWAAAVTTAIDEYCQSKRVQQVREKKSALDAIRVVDAEKVIDDACSALKHEWGDGSDHELVCSVNCRMRNSTIYCDWTEEQWEPASERLEVWKVNPGLPTTSSFDRCSCLGGVRLEKGEQILSVFTVQASSVVIISVSAEGTFVRRAQFPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL69</accession>
    <name>A0A8K1FL69_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
            <ecNumber evidence="1">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Poli38472_002483</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EC" id="2.3.1.86" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4251012at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013565">
        <property type="entry name" value="Fas1/AflB-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040883">
        <property type="entry name" value="FAS_meander"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08354">
        <property type="entry name" value="Fas1-AflB-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22235">
        <property type="entry name" value="FAS1_thioest_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17951">
        <property type="entry name" value="FAS_meander"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="20">
        <location>
            <begin position="3149"/>
            <end position="3676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="3755"/>
            <end position="3779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="3759"/>
            <end position="3779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TMW63542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="3943" mass="431718" checksum="821E27E5B802E361" modified="2022-08-03" version="1">MEKEANLVRSALRGKDFKFVVEFDGHGAVYWDELVALYEQQGESVRAFIERVAHALKEDSSSEEASKSTGLERVLDIKSWFAKTTEAPTSNKLSRAFFSYPLIVLTQAANYLVFLDTNKLTHEDVVKSTACAIGFSQGVVSGALFAAAKTREDYETLAVAVIRYMFWHGLRAQEAFVDVCVKNEEVIEESTPMLAVRGLTKAQVLKAIEVTKRRTRRDGVQLSLVHDRNVFSVTGLPSALKAFKRTLDGFMAKAGEDQLRIPYSARKPSGSVNYEPVSCPVHSSLLGAARALVAEDVERMGVVVRGSDLQVPMYGTSREAHNLQERGEANILPELIDMQLTSSADWPATWKNVVSSRPDATHVIALGPDGVSNTSRAITEGCELEFISHTTKLSSLSSSLGRGVWEIAFGPRVNPTTGKLENKYTRLLKKDPVMVAGMTPTTSLNGVNLVAAIQNAGFHGELAGGALTEPSIFECAVHELVSKITPGLGVSINMLYLNAKQWGFQFPMVLRMRKSGVPIESITIGAGIPTKERAIEIAAQLQEAGINLIGLKPVSVDGINAVLEIASAVPTMNVMLQWTGGRAGGHHSFEDFHQPLESVYAAIRRVPNVLLVVGSGFGNWEDSVEYLTGDWSLKRGWLSKMPVDGVLLGSRVMVAKEAATEPEVKQLLVDTPGIASELEWEKSYTDIAGGIVTVTSELGEPIHKVANRCSLLWREFDTKYFSKPREEMELAIRLDKQSIIERLNADFQKPYFGCKVDEGGETRSAELEEMTYSEVLGRMIDLMYVEIEGRPRRWLHDSFLDRVVKFMSRTEERFRRAGGRGVFNTSSLESEPRATLQKFLAVYPTATMTLLSIPDCDYFVSLCQTGGKPVNFVPVIDRDFKTWFKKDSLWYSEDLDTVPNRDAQRVCILQGPVAVRYSTVVDEPVGKILGDIAAGFTDVVAKQPGMTIKNEEDEPLSPRCSKVIAGVSVEATPNGYSLKLPKTLSELPSHDTWFAVLASLADSEWLGAVLSSKEVCQSRKWVTNPIRSLLRPQPGQTIRVKGDGLLVFDEELRSDSEPVIQLAKSADRIVLTLYEVRPASSLLDSAVVEYHQYFHYESNVACPVVQVDDTAMSDIKAFYARFWVAGKDNEAGSCLEACNSSLTSTFTDEFTVTNVDIAQYNAALALGHDDSSVLADFAVVACWKPLVAALFSKELPGSLFNLLHLRQSHRLLSTAKADRLFSVGDDVVSKVNVSSVRIVSNGVIVTAVALISRKALGVEMEEVLEPLVQLTTEFLVRGEFSDYENTFANENSNVIVVLDRSELVEILLSKSWYEHSTGVLALTIGDTLELVTTTNTRFKSMGTISSILVSGTVYRQANGQQEKVGTIQYEGHNVKGSPVKLFIDQVNAQAAKEGILPNGGHFMLAKPLEISVPVSAVPYAVASRDLNPIHRSKYAATLANLSDGKVVMHGMWTATKVRSLLVEHFGGGIDTNVLVYDVTFSRKVYPGETLFMQARHVGLKGGHKVLTVEVANRVGGIVLSARAEVKQPPTAFVFTGQGSAEVGMGMARYKESPIVREVWDRGDHCLRELYGFSILDIVRRNPSSVTVHFGGRQGRCIRENYMKLRCDDPETGELVPLLPDINERTPSYTFSAPEGLLFSTQFTQPALVLFERAMFSELQTAELVPDDAVFAGHSLGEYAGLCAFAGVFEAAAEVAFIRGTIMQNVTKRDEHGRSDYGMVAANPSRVGEYFTEEMLHNVVDTIAEASSKLLQVVNYNVQDSQYVVAGDNVNLEVLSTTLSYLKKNEDADLFAVVAVALKQAREKKKKAVQAGKPFMVARGVATIPLIGIDVPFHSKAVLSGVPAFRTLLRTKFDPETLERQLPLLVNRYIPNLTATPFSLEKSYFEKVYEVTKSPCLAEVLDPMQWDLTTKAQRTHVLIVELLTYQSASPVQWIKTQQHLFTIGKSGVRRIVEIGPAPILTNMTGRTLLMGKFQKIPREVLWYQRDRDVVHFQMQNDYSSASEYARSLAVVDVPSTSEVDIAAEECNAPITVTPGVAQVNVTAPVDGAAAPVIDAPVCALHVLRIILAMRLSMPLTEVSDDADVKTLSAGKSAVQNEIVGDLEKEFGDSVPEGAAELSLKEVANTFSSYKALGKVTSGLISKMIASKMPGGFSMSSVKSYLNGTKNLPAGRAESVLAHSLLFTPQARLKSEAEAKQWLDSCVDGYASFAGISLAQPSVVAMGSVPQFAAAPISTPTVNDKPVDAKHALIVLLAAKLGKSFSEISSDMTIKDLAAGKSAVQNEIVGDLEKEFGSGPDDGAEVKLLDLATKFPGYMSPGKVTSALIAKLLASKMPGGFGLSPVKAYLSSERCLPAGRIESVLVHSLTQNPKQRFVDEAQAKAWLDSVVDDYAKFAGVDIPYLSKLDGGGVAMTSQSVGVIPTDFDKRLRELIAGQVEALNNYLDHDPLEWHRRIESEVELREHLENSIAVWTKEHEEVYTTGIKPLFDSNKERVYDSYWNWALQDAVAMYHELCSLGNAGSNEGARDFSTVIDSFRACLCNRATPALVQIVRYMAKKLSDEVNSQCGEAVEGLAGQVEGEMLIHPVTISRFQSMRAELRILDTGKIKVHQVPRAGVPDAVHYVDDLARGLEYWLDKDDVLVECDHESVEEKNRNLKSSMIQQSSALRMGLEENLHKLVLPHVHIRQPSDADPTLRLFDVEMTCTLLSCMREMATSGVSFYGKVALATGCGRDSIGIEVVKSLLEGGATVIVTTSSYSKTTTSMLQSIYQRHGSRGSRLITVPFNQGSAEDVHALIDYVYDKQKLDLDFVVPFAAVSEVGRKLNEIDGRSELAHRVMLTNTLRLLGEVVEAKKSRGIATRPALAVVPLSQNHGTIGGEGLYSESKLGLESLINKWYSEDWQDHLSVVGAVIGWTHGTSLMTNTEIVCTRVEELGMRTFSTQETGFNVCALLHPDIVALTNDGPVWADLSGGMGQIKNLKSSMEKIYESILYEAKAHAAVCAAAKGEANLRTVRDNSPSFRPLPRANLSGFFCNEFPDTSCAAKRATTGKQDLLQGMINLREVVVVAGFGEVGPWGSARTRWEMESFGEFSLEGCIELAWLTGRIIYQDGNWVDAKTKEIVPEHDIKSRYEYEILEHAGIRVVEPELFDGYDPHKKLFLHQVATDKKMAPIDVADYEEALEFRNELGKENVDMFQNDSGAWMIRLKKGAVVSIPRAISFDRFVAGQIPTGWSAERYGIPKDLAQSLDPMTLFALVSTMEAFVAAGITDPYEFYQYIHVSEIGNSSGGAIGGMRSLRRIFGSRVLGKTVPNDTLQECFINTAPAWVNMLLLSSSGPIRTPVGACATAAESIDIGADTIKAGKARVVIVGGFDDYGEEGAYEFAQMKTSSNSAKEVSMGRDPREMCRPCTSTRDGFMESHGAGMQLLMDAELALEMGCPIYAVVALANTATDKIGRSPAAPGLGIVSTAKEDRGNASSKTPLILNADYRRRQFDSEMKSIESWYDCEKEYLGDSDGEFLEDMKRRRVRSAQKTWGNDFFVGRPDIAPLRGALSMWNLTIDDIGVATFHGTSTKANDKNESEVTQLQFEHLGRTKGNVLPVICQKYLTGHPKAPAAAWMTNGLLRVLDTGRIPGNKNMDNTCSTLREFDFLVYPNESLQTTGIKAAILRSYGFGQVGSEVLFVHPDCLLSTLSADELKGYSHRRDSRLAKMNAYFQKSLCGKHTLVQVKDSAPYTATQETAVLMNPNARAKFNPAANTWLYGVSPGDQRESKSQEEQNRVVPEKDPFPKKAMKATRDETSYLLHTIAQGASEMALSSSKKTGLGVDVEPIATFENLKGRDDFIRRNFTEQEMAYCFSAPSPASSFAGRWAAKEAVVKAISSAAPNESNMCKGASASLREIEIVMTTSGAPSVVLSGHALEVFSQVGLASMTVSISHSGDYAVAQALASYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FL77</accession>
    <name>A0A8K1FL77_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FL77"/>
    <dbReference type="OrthoDB" id="70387at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF5">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="52573" checksum="61192E471A0DBC7F" modified="2022-08-03" version="1">MVITHYKGQWERSNGWPLLPYTQDKTSQLLFSSTARMAVPLTDPRQRALRVLSDVGLVHHICSLQAGLPIDLYQFWVLHDAPTALKQWPLSWKISHLGSLVVAKGTLRLLDMYTRVVYFEKHTRRRGKSTYTQRTPKLDWVAREAIMNNRADVLQWTFDHNTPCDRTPERLWDYALSWPRGDTRVRDTLDANVPIALADFPPYTFAYGILDTEGFAWLLAKFPGIQLPPVALEKAAERGDLAVVRFLLENEMTECRERAFEYARYGMSGGYMPYGSSCYGGDTSHYGDPRNVDHFAVLAYLFDNCPGSMYESTAEYLIAYDKPEMVALVAKHIERIQCLREPWIRHCESVAQSGRLSDLQAWHELGMILVPISIDTVSDLAVVKFLHEHGLARATATAMDSAASRGDLALVQFLHENRTDGCAEVAIDGAIANGHDVVVKYLCEICTRGDATKEEIEDTKAVPNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM14</accession>
    <name>A0A8K1FM14_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM14"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="34687" checksum="07D5013AAB12DBD5" modified="2022-08-03" version="1">MTATQPAPVATPTTAPTTEPSGPLLSDILRTNELITTQTDAEMIDEIVGLPIPSEEDVDAILRAVEAKMAWEEIERRIIAAQPHPQPPADHFLILATGTAIKEPSQESYLKRFHAEHGNPVVADLIARNQIAQIKRLPKNMQVFVRSREAARKLSKQWVHFFGGQYKFLPWNPLADYFFIDIHGVENTTYMECLRSIFYHLGSRPIYDTYTHVTTSGIAAGTRRFYYAFKECPLPLRVDGLPIDQLIIHDRKFTVQCKGVRTFNTGRGTPEEYDLYKWYFVARNFNLEAYGSIAFSGDNAYISTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM99</accession>
    <name>A0A8K1FM99_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM99"/>
    <dbReference type="OrthoDB" id="102768at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="371" mass="41919" checksum="CDE4F3A363AF5A5C" modified="2022-08-03" version="1">MVPPTPAAAAKRTPQKVVCCRVCEQEFPSKSLLRAHLAHSKHYDARAIPMNKLSCRFCNESFESKSLLGIHTTRIHDNLFQYPRQGNDATQHSKPKPRKSWPPANTMMSQKKEQAIAWSRRQKLAQFQADTSQEPVGLELCGPRHVILDMDNILYGMRFSHVYERVEDAQSGDELRMNIKELTKLLGGQEAQKTTFQAIYARTSPNIAAIFEQCGWQVTRPSNHARDTLLQWLVQDCIKPGSNTSEATTTIALVTGDSCAFGSPQSDFRLLLNHHLASGRIKVEVHTWLHALHESYLEILSRHPTRMTILPLEDRAATILYRYCPWGAQEKHLPVSPVGDEEGKPGELDWVLLATRLEELELCMSETSGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMS3</accession>
    <name>A0A8K1FMS3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMS3"/>
    <dbReference type="OrthoDB" id="167235at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="51678" checksum="0D493DCA71710C27" modified="2022-08-03" version="1">MDGKRTSDVSYDAEAKRTKTGYEVVINGERYVDLALLVRTPPFAAHYVKHCKKSVTRLIEQEELTEEIVNVSRENVALGVLAHKTVYRPASDLRLAKKEGKMQMFIDRVQGMTAPPAPPLINDEDIRFFRDAFQQDHKVEMRGKRTLRGIFFKVKHVGQSIGTKTLGDDIQLKNAKAEEGEDYIWFLVDKHGERRRVLFVTFLGLMRIIMRSNLPGAAPLCMWVCETVFCIGFGTAKQKDALGRSLLTKETVDLLTKRCANKIACVYLLETTRQSPEDAKKVYKFGFSKNLGRRMGELTSKYGLEAAIDTLIILPLNLVSKAESNLKHILGANYTYEQEDDTELLLLSDRDRAVVRGAMRTVGETFYGETLVHTHQLQMLKQDHEFQLISAAKDHELQLVTATKDHELQLVTAIKNFELVKKDYEILELKNEAQARRIKELESMLRRMNEPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMU5</accession>
    <name>A0A8K1FMU5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMU5"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF99">
        <property type="entry name" value="RASGEF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="426"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="954" mass="106476" checksum="D005B6DCD1F59FDC" modified="2022-08-03" version="1">MATTVVKEGPIAVRGHFMWRDRYVTIHDNQLTIQRSKHGAVKGKIDLADPSVQVVFHENQTQFTITTAQGRDVLFQCPTTTVRDEWLGAVFVARGPSDTDAESDAVFSTMDERTGVTQDESEASEIEAVFLSREPSCDSNDDGGAYNDTLMAFQNLRSSMMEFHFTSIDEDTEENNQEPAIVRQQEEATRRRCVNTLAFFIQSVPHGGKAVLLHMDVLSQSFGITLDEIVAVLGETQCEKPRRGSMASVGLQKLHVATFVRYILFHPIYNKRQSGQADRINELVDRYFPHCRLRRFSHDVDQDGGEQSRASEPPPHTFELDLTFHTPPTTHQQTRNKPNRPDPSVMKRKRHSFPNIMMPISLSGINSNNPIRAMAPPVPLLPQRSRSESMSSLSMSFLLPAANNDSDAFRDDVIVEPLRQLLWRYSLQDVVEQLSLLHHRQIASNVLWEFITAPKQAAKAITEHFNRFVSYLVWSVLIEDTPKDRAEVIESIIAMAVAASELNNFHLVMACVGCLGDLPLMPARLPLTWKKVRVRFKTHLQALRTLCDHTGGFETLRKRQAAESTRSSCMPFIGVIGVALERLRLTPYYSEGSGRTVNLDRLGRQYTALLPMENAILKAYKFSAIDTLQTTFERLDMSFSSSRLLQLRSQQILTMENAASNASLRTSSLYRNRKTELAAGDAGDDSPPFLSFHQICCILATTASSSERIQICVEALLTDDRQALTRSLRSFWRELRQTIHSSACHVAVHGTRRCVESLHRGILTQKSNELQQVTGLDELAVELDRGVYAAVVAAVTQPIATWFFAKVKHSLQAEDMRLLSKIKSDNTTSPTTTHSSSVVVPIETDVAPLAMLDALTQAIQQLIPLNAPQDLRAAALLAAMAQRRLMLPHPASVLYVLQQTLDVLFLSRPHRDALELFDTALSSLTKAAAVPSRRASSAASMASVRSIASVRPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMX1</accession>
    <name>A0A8K1FMX1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007924</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMX1"/>
    <dbReference type="OrthoDB" id="179952at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="254"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW65282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="327" mass="37757" checksum="97EB763E3935B037" modified="2022-08-03" version="1">MLDVELPTDVSPSFGGGKTLTQRTKADGDVPVVLKADFTDPVKLVEEETVVETHQVTAETNFARDAEEEDDEDKYVRWETEDDESDEGDSDYREDEDDSEGDDMDDDEEEYRRSLEMELDDDEVSDFYLNRMLEERDRMEGEDAEWVEKYIQAQREWKEKYGTSIDEIDLDLRLAGLKPKKKKKKVVRKKRAKANGAPYLQVIQEAWNGRVMPLLPPRFHDLAGERMASLVIALLFVLLALGIQFPSFIMSAFPQIKLKYFNVSARAESIRLAFYIGNVPFEDIRLNREEFAVLKETLPYGQLEAVQFFFFNCMRVFLVSIAPVPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN61</accession>
    <name>A0A8K1FN61_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_012955</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="763"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="861"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="945"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="985"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="66"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="400"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="723"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1046"/>
            <end position="1284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW64333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1290" mass="139638" checksum="793DBC09B42D6C82" modified="2022-08-03" version="1">MSAYRPSSTDYVQALTPQAKDKISKESTFVVAEDTKAAEDAPSLRLVPFTQLFAYADKLDYLLMGVGTVSALAAGTSQPVQMLLFGDVVNAMNPVGTTEATVSDQLSHDVNIVARNFALVGVGVLICGFLQVACWSLTASRQAKRIRSAYVSAILNKEMGWFDVTDSKQFSTRVAESTVTIQEGIGRKLGDGLHYFSLSVTGLVISFVKGWKLTLILLAFIPFIAVAGGMTMNFVARLTQESIEANGKAGAIAQESLSNIRTVHIFNAIDHFKAKYQSILGLSAKAGIKKETMMGLGLGVSYFGIYCLYACGLFFGAVFIANDREDECTGDNCYSGGRVLTVLFSSIMGSMAMSQAGPSMQALASARTAAYDVFEVINRPSKIDPLSEEGVKLDKVNGSIQIENVSFAYPSRPDVRVCSNYSLRIEAGETVALVGPSGSGKSTMISLLERFYDPLSGHVKMDGVDVRELNVQWLRQQVGLVGQEPILFATSIMENIRHGCPGASDADVINAAKMANAYSFIKDFPEGFKTEVGERGTQLSGGQKQRIAIARAIIKNPAILLLDEATSALDTESERIVQESLDKLVAASRRTTVIVAHRLSTIRNADKIAVHSGGAIVELGTHDELMQIANGHYRALVDAQSRVAASEQIDIPSVDLQRDSSLSSRSRSLSGPVLERSLSKLSGVYDDEEKTENSDVEDESLPSVSVGRIWQMSLPELKFMVSGSLGAMVTAAMFPLWGYALTKATVLYFDDITRHEMLTNMRYWSLGLIGFGIVFIFSATLQNYSFAHVSQSLISRVRLNTFSAMLRNDVGWFDRRENSSGVLVTRLATDTTVLQAFTSDTLNFGLFNLSLWGVGLGVSFYYTWQVTLLLIALSPALILGFYVENRVAQGTMSSKKNNDADTAAASLLSEAITAVRTVASFNMEKYLNTTYTSLLDVSKSADTKIGLGGGFAFGVSKGLVFFTVALELYAAGKWMASGDVTFESVWMVLSIFMFNSNAVGLSSQNMTDRGKAKVAAARIFKILDDAPAIDAASLSGAKLAGVHGDIEFRNVVFAYPSRPDAQIYKNYNLKIRAGQTVALVGASGSGKSTAISLLERFYDPAAGHVTLDGTDLRQLQLPWLRERISLVSQEPVLFAGTIAENIAMGKPGATRDEVVEAAKRSNAYDFISNFPNGFDTDVGDRGAQISGGQKQRIAIARAILRDPEVLLLDEATSALDNESERIVQESLDRLLAQKKRTTIIVAHRLSTIRNADLVAVTKDGEIVEQGTHDELMSIRGGIYQGLVAAQMRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNK1</accession>
    <name>A0A8K1FNK1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNK1"/>
    <dbReference type="OrthoDB" id="822380at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938:SF35">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938">
        <property type="entry name" value="RESPIRATORY COMPLEX I CHAPERONE (CIA84), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23584" checksum="DE1237A6B0F9063A" modified="2022-08-03" version="1">MTRQQDDTPLWRWDEEEATQELVRALQSGTKAETRMFLRIVLKWMKIGLKKDGNKDQVSIEKAFALVDWMVRVSTEGDTRLNIEKQDGLQPNQALHSILTASRRTGSAFESQRAFDLMLAYGFTPDVVAYTTLIDVLARSVDTHGALQVYNSMRDSKNPQPNVVTFSTVIHAIGFTTLVDPSRCLTLLQQASVTEDEERAMDDALFLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQ50</accession>
    <name>A0A8K1FQ50_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQ50"/>
    <dbReference type="OrthoDB" id="164552at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="281" mass="30471" checksum="65C32A774ED9FB0A" modified="2022-08-03" version="1">MSLASTTLTSGTTVPVMIASAAAGNPMNGVPNATSGSLRVAFGPLQNSLTTLSTSGQIFPFTTSRLYIPFYDIANPSQIVQKPIKKANYLDCYAQYFTQKAGVGVSTTQQNVAFSFQLSASLKNIKYVALIPFAETSSGHFSNASANLTQQFASPFDSAPWTCQPGASVRNFQIQIGNENIFYKTIDYDYESFFDEFSKIAAINGNLSHEISNGLVDFTKWSNVQRVLLADCSRVTNPEVPQSVLISGVNNCTQGSNYLCLIIYGRSLSVDRLTGEIVDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQS6</accession>
    <name>A0A8K1FQS6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_001890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44077at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="398"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="507"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="541"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="590"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="623"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1404"/>
            <end position="1669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW69734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1683" mass="186960" checksum="A6957287DC202F39" modified="2022-08-03" version="1">MGLAMGDVDALMRAATDGDLEHVSKLLDGGCDLLSRDMDGQTALFYAASAGKVDVVRLLLARDQGRTLVKTAGNDGRTPLFAAWEKGYFHVIEELLSHDLDVAVIFPGGVNALHIVALTRASNLVEPLLRGGLAVDGMSYDGRTALHFASQFGHVDVVKQLLANGASVGLCDSYGQTALLLAAGEGKMDIVQVLLERDVDRTLVNLRRNTDGWTPLFAAGAGGHGDVFEKLLKHSGLAKEQLLQDASGPFGHAGVLKQLLAHGADPNISDMDGWTPLHWAARNGNIDVVSALTSSSVAGIRADPYAREKAFGCTPLHFAAEKGMVDVVKALLSNKVDPNVPDNGGATALHLAAYNDYPDVVKSLLECEVTVVDVKTSNREFIYTTTCADDDFERWEAKSKTALHLAAERGYTEVVNALLQYRANVNERDADSNTALHHVTKFSRLRDSDDNCCAIAMTLLEHGADEESRNQALCLASLRDGCDMVDLLLGLQVDVNATTCALGEDRTDWTALHCASSQGNVEVVKRLLAVKTVKLNARDKTGKTPLHVACQKKDSKDDWAALNPASYSGRLDVVRELLALAVDVNALDEDEHTALHLASRWGFLDLVRALLGQRVDLDASDKDGWTALHHASFRGHTDVVRELLARGMNPAARSRDGATPLTVCFLEMPLSSPFVHKNSLNYGSIIEEAVFLRVLETSRALMSFGALHDGPLEKFPLFGDEHRALAAIISICLRHWTQEQQRKKPSLTALPLEVFKRGSKAVETYLTEIAASDEKDLVWRRKVCVVGSSKAGKTSLVKSIDSMTPTMEKDDDRTIGVDLFRLEFKEDVKSGSTTHQRSHTVTFWDFAGQDEYHVAHTLFFSRRTLYLLCVDVEEFDEVVRKSHACEDEDEAESLVLAFVQARVWRWIRLIFARQPDAEFVLFATKTDALVGDTQSRLKDLESELLSIVAELKQTYKEEIQREIDALPDSPTNDQGESPNDERIRSLQSLLVQLETSVPTSWICLNIRESSSLQLARTSIEDVVRQSGQSFAMPDKYARVLEKVEELRQKARDANMKNRIRQSFRSLPDIIKTLMADIHDLTEDEAMTILETLHDLGDVLWYARDGHHMLGDTIILDAELLIDFIRQIVCHDPTMTPGVNNSGAGDNALLIQAMKQHGTVSNKLLRHSFSLWKRLAYPNQLLQFKGLLEHFNLAYPGDGDVMQADSDVVVPSYWRFRGNQIDLTGLAPLSIGDIDSSHINHFVWEYYLGDNSAELVDTVFEQLAVRSYHVFPNRMIHGRCVESAQKGRLAIRTACGMVGSRGPVIHVEVLGKADHDPSGWLRDVHKALEDVLKMFPGILVAREAVAGRHTCNLDKCIPKWRGLPENQREAKLREHSWLPNGVVEWFRRTDGGVRDWFIPPESIVKHKGPAFAAGAFGAVYLAKWQHTDVVVKEMLVSEMRRFLKEVTHWYGLRHDNVVRFIGANDKKEPYFIVSSYAAGGELLSFLSSEKENGRDVVWRKLKEAAAGLSHIHRRGIVHGDLKGSNILVGKDGTAMIADFGLSFSESGSSSVVTEKKNTLRAMAWRAPEFARLTEERPTRKSDVFSLGMCIVEAVRGGNPWCRKSTTCPREECKCWSNEEIRECLRNGQVKVYKPEVMTEAQWELVKKMIALSSSDRPELSEVISKLADFAEEEKRVALEKENPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR19</accession>
    <name>A0A8K1FR19_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR19"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="18719" checksum="D54A5CEE07844C58" modified="2022-08-03" version="1">MESSSVARFLGRPASESVMTSLDEELRRLHAKLAFYEHPIERFDEPVCNQPRESDLARVLEREQSVAARWRRLRRRWRRAFQRLVDALMPPQNQKKHEERPWCLRLHKLGLHGKCRHGPVAMVLEARPPPSRRHVTLDEHARFRLGLIGLHVDDDVESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2A5</accession>
    <name>A0A8K1C2A5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">serine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013876</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2A5"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000026">
        <property type="entry name" value="Seryl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="142"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="282"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="353"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="9">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="453" mass="51642" checksum="D214389FDF441EF4" modified="2022-08-03" version="1">MPIDINKLRAERGGDPAAIKADQQKRFASVDVVDQVVALDEAWRKKQGEVETLQMKINSLQNQIKELSKAKQDFKAISDERKELAAKVPELKKEADEIKETLDKELAKIANYVDPSVPISNNEDDNVIVKEWGTPRQQEGLHFHHEVLHRIDGYEPERGVNVAGHRAYFLTGFGFLLEQALMSYATAFLMKRQYKMLKPPFFMNKDIMAGVAQLDDFDEQLYKVIGEDEKYLIATSEQPICGYHKGEWIQESSLPLRYGGFSTCFRKEAGSHGKDTWGIFRVHQFDKIEQFCITEPEHSNAMHEEMIKTAEDFYQSLGLPYRVVNIVSGELNNAAVKKYDLEAWFPAYKEYRELVSASNCTDYQSRAMEIRCGVKKENQREKKYVHMLNSTLCASTRTVCCILENCQDENGVKVPEVLVPFMGGVTFLPFVREAKVNVQAAKMQKAAKKKGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2P0</accession>
    <name>A0A8K1C2P0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2P0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="198" mass="21072" checksum="1C9591A27F1E3B2E" modified="2022-08-03" version="1">MKLAIRIPGLVPFLTPAVVQGASPPFSVHFKPGPNKCVLFPAPQPSNVAYLSGCTGSADEKITYNRATKSIAMSTNPNGCWSMSDSGKLELRLCNAADSSQQFVFQQLGPSYAYIKLANSPSQCLELRAEGGVLTPCVATPENQMYSIEEVSVSDLATPGSDPNPNQPGGQAPDLTDCDQLEALQVNTPALRVRASEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C400</accession>
    <name>A0A8K1C400_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C400"/>
    <dbReference type="OrthoDB" id="114178at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="59517" checksum="9359F292134CED0B" modified="2022-08-03" version="1">MVGVFPIPRDALPEVIVSPEEHYGRKMQMNQMLESLVEEYERYVDAGREVDRRRWSSSASRDRLKLYKERRIPRVNSKPKSKPWAMTDEESESPSSPTGQSRQYRRDSSVLGSVLSFQSSSASSTLSEEAADTMQLSLMVGESTGRMENAMIAAHATTQKDLALVDVFLHEDVADCSVLHTMEGPSVEDPYHFLGYKWFVKKSPAPSQIVRHRDSVYLEGAGFTKTKSGEILGYHIMHSVDLMGFPELREHNCLRSSQSIRSLYRQRPGDIVEIFVLGNVHIAGFIVGPLASMFVTETLLSMPKMIECGEAKRLTKMAQDMEAQRLAKMPNGKHPNTAICGLCHQTKKRFGSSVSNCEVCGTTTCSRCRVPRRIFVSEGLLGRFVKVSCCKTCVLAAKSPNLIQSTVVEAKAKDGMDLKNRVSRTSSTSTASTARTSTGSVARMGSLPTAMAATAPNHSIMSGTIPEDDTLNGSFKSSQWTPVVSSSMPSSLPSTMPASVDSKAELFMRMLELQQRAEDTYNTLQQNEYLMPGAPQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C554</accession>
    <name>A0A8K1C554_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_006630</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 13">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. EYA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C554"/>
    <dbReference type="OrthoDB" id="167668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028472">
        <property type="entry name" value="EYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038102">
        <property type="entry name" value="EYA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10190:SF16">
        <property type="entry name" value="DEVELOPMENTAL PROTEIN EYES ABSENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10190">
        <property type="entry name" value="EYES ABSENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR628472-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628472-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW56620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="498" mass="56684" checksum="A394BAB2AC41EE3E" modified="2022-08-03" version="1">MHQVEDGPLGALPYRFTRWDSTECNWTTGMTLPGICAPPPPIFHGYATAAASKWVEQSAQRTAMTMTAVIRAQVERVLVQVVMLPVVWMSVCCALGAFMGIECIMTLRKTLTMEEPTTVHRPKHKNENESSDDKADLNDRPVKKSRLRRDETKPRSEAKARATSEKDTTKTTLLITVQATKQDVEAVTKWTSEPSPVTRRRRRRVYIWDLDETLLLFASLYSGQFARTHRKDIPTSVALGEQMMTYLVAVLDRHFYFNELHNMDIDHIASLVENPASAEQDSKAGDSKKASDDKPVDRRAAIYKRIRAIYEREQPVDFLDETQSHWYAAREALVAAIDGFSGKWLREAREVLELTTTRARARPTHKPADGEKTTRDEFDQFGSTEEGEEDDLNVLVTNTQLSPALCKCLIYNLHTYFPIETVYSSSKVHKYECFERIMTQYRGSDVEFIAIGDGAEEEHVSRTLGIAFHRIGTLDDLKQLRYELELVERPTAQEAKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6K8</accession>
    <name>A0A8K1C6K8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6K8"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001438">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="320"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="644"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="28"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="127"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="866" mass="97917" checksum="421A22CD35901E03" modified="2022-08-03" version="1">MNRIFGRKKPDVPHVNVSDVNARVDGRATDLDMKINKLDEELRKYRVQMQKTKGPALNAVKQRAMQTLKRKKMYEAQRDNLTAQSFNLEQANFAIETSRDTMATASAMKSAVAQLKVETKKINISELEDVQDDMADLLEDMNEIQEIMGRSYGISADIDESELEAELEGLEDEWAEEEANAVADEATPSYLAPTHELPAAPVGVPERSQPARRTDEFGLPIGYQIILKGRLFGSWLVESYWPDALGSPFDQIEILAVDTMPPRVKKERGKKKESRKAAAEEKKKADVAASLENMSLADRLAEEGIIATCAHNARGVHKNFKDINVTNFSLLYHGRVLLEETDISLNYGRRYGLIGRNGSGKSTFMNVLGARGIPIPDSIDIYHLKHEIEASDMTAIEAVLSVDEERNKLQAEADELSEQMLDENISEEDQQAISDRLTDIYERLEEMDADTAELRARSILAGLTFSPAMMEKKTREFSGGWRMRIALARALFIQPTLLLLDEPTNHLDMEAVVWLEDYLSKWKKILLMISHSQEFMNEVCTNVIDLRFKKLEYYTGNYDMYVKTRAEREENQMKKYQWEQDQIKHMKEYIARFGHGSAKLARQAQSKEKTLAKMVREGLTEKVVADSVGDFKFPDPERLSPPVLMFQNVSFGFPGQKLLYSGVELGLDLDSRVALVGANGAGKTTLLNLVTGDLVPVAGNVRPHSKLRVARFSQHFVDVLDLTMTPLEYFRSILNKSIEEVRSYLGRYGISGDVQTQVMSQLSDGQKSRVVFAYMAQQNAHILLLDEPTNHLDMESIDALARAINNFSGGMLLVSHDMRLISQVAKEIWLVEDQKIRVYQGEISDFKMRVRKQLKLADKPKVEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7K6</accession>
    <name>A0A8K1C7K6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7K6"/>
    <dbReference type="OrthoDB" id="167050at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="74" mass="8622" checksum="44A88E51D49E6DF7" modified="2022-08-03" version="1">MDEFKMSKLCSTCHREKLPFVLESQWSMIQGKMLVRVPFILQFSLAHCGVDFTFHFDWLAYGGSTANSTHRQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7S1</accession>
    <name>A0A8K1C7S1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7S1"/>
    <dbReference type="OrthoDB" id="110859at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW58224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="196" mass="22430" checksum="D49AED226AF5C45D" modified="2022-08-03" version="1">MSPDFYKCLMSVASGMHDERLERVAFEGYFHSLVRRRQVIKLHLFEYLNKKLTNLSIEEKTPQSLGCLTWTELPVVVTEGENVDEGVYVMTEWAKNPSKMDYWIPNTSLFETVDAVAKWKEDGQVQFALLQLTKGETHKCDGDVITKLTKPFLDHGHSIRYIAIVPTEEIQKNLSPVVVKGVHADMLRVAYLEDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7S4</accession>
    <name>A0A8K1C7S4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Roc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_011720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7S4"/>
    <dbReference type="OrthoDB" id="93327at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020859">
        <property type="entry name" value="ROC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51424">
        <property type="entry name" value="ROC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Roc" evidence="4">
        <location>
            <begin position="44"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="179" mass="20820" checksum="CE24989FDC73E9DF" modified="2022-08-03" version="1">MLAAIEFWVKQQREEGHELTELPEEVYMRGAVDVRAFFNSIKASNCLVYRKKLFVVGPSTWGKTSLIKSLTTRTSTLEDADQRTIGIDLFSWKFDNTNDTGERKTNDVSIWDLAGQDEYHSLHSLFYSKRTMYLVCVNLKAYKDMLKRENLMDRPGAVHPRMDAFVNHNIYSWIRGVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9F3</accession>
    <name>A0A8K1C9F3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">40S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_007008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9F3"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16064" checksum="F5D51864C73F7CF1" modified="2022-08-03" version="1">MSKKVAKKEVEEVTRVGPSLKDGEQVFGVAHIFASFNDTFVHVTDLSGRETIVRVTGGMKVKADRDEASPYAAMLAAQDVAAKCKEVGITAVHIKVRATGGNRTKTPGPGAQSALRALARNGLKIGRIEDVTPIPTDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9I4</accession>
    <name>A0A8K1C9I4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anoctamin transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9I4"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="246"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW58954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="723" mass="84034" checksum="463EDDF7B939B444" modified="2022-08-03" version="1">MDSFLRRRGRLQPPEPRPGIQRHVKTAARAPTLMQRVVRTTIERNVAAFSKDTESITRHPDADYCLYVELVEPEENQSWGELEAHQIVDTVVMLLKDQGCDIQVFPLEHVDSEVLATSKDVTRAYYVTICSAGMRETGLTGALSARPIPEWVKRQAAYKLVTPLTGAAHSQQLTRLILQEYRLLDDICLRDNKKIFAGGQRLFCELGHHKDKLDFDIFPLHREVERNRLISKWRVHLFDKLPLVDIFAYFGPKLAMYLAWLEFYTEMLVLPAVLGVMVSILGFFQAESYCLLSFLISIGTSVFADFWRRRQRLVEYTWKYQQLMESEAVVDLETRPEFQGEWVIDHVTEQRVYDFPRHKRFFRQLLAIPLLLSMCCVVGGYVVLLNLLSEHLRSVYPVCFRKHKNIDAIEKVGMSLGQCTTAAHGPGVLNAISIMVLDKIYHRLAKRLNEFENYRTTAEFDEHLVMKRIPFNIINSNASLWYFAFYMRDLDRVRDRLWILMVMMQFLDNLKEIGLPFVVSLYARFLATDKHHQQRTEGQTLVSESISERIQRLRTQQRQVHYVDTFADYKEMMVQYGYVALYTPIFPLAPFFAWLNNVVESRSDFLKLVNSNGFQRPIVKHTHGIGVWERILVALSVIAVIINCALVWTFEIKELVPSWSELHQFMLLIACEHLVFIIKGLLNWAAPDLPTWIQNEKRIAALSSTRAQLLSPTRAQTKELLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9X6</accession>
    <name>A0A8K1C9X6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9X6"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451682" description="Kazal-like domain-containing protein" evidence="4">
        <location>
            <begin position="18"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="133"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="203"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="262"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="379" mass="40457" checksum="B0459EEEEFE3EFC6" modified="2022-08-03" version="1">MKLSLCLLVTALVLTSAQESPTPPPIDCSMLINCSTEQAEPVCASDGLTYRNECAFQSAYCVEPNDAFFVVTEGPCPDDAATYVVDDVVDPQPAVIAMPTEVEGEAEARVLETFEFVTFSEPERISTPSPAPLASNPYCTLECSNDVKPICGSDGFTSTSYINDCYLLAAKCTQPSIDKLHDGLCIVQPPPVKAVETHFSTLEVTRPKCNAFCDRVYEPVCGSNGITYANHCLLDYATCQNPRVKLLGEGKCADLLGSAPGPSTSSVCVPVPCSVVDAPICGSDGNTYMNLCLLTNAQCDNSKLLVLHEGECGADTILTCASLTCPQYTECREEEDTGVAYCADVCAPERCSQYEECKLYDAECFTAPCSPVATCVPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAD5</accession>
    <name>A0A8K1CAD5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 12">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-ornithine + 2-oxoglutarate = L-glutamate 5-semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:25160"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25161"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 12"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAD5"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW59646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="433" mass="48211" checksum="23F939DD457AE4BC" modified="2022-08-03" version="1">MNAKQLASRLSTTAARRAAPKQTRSVWTSQQYIDREDKYGAHNYHPLPVVLKKGKGCKVWDVEGKEYYDFLSSYSAVNQGHCHPRILEALVEQASTLSLTSRAFYNNVLGEYEEYMTKQFGYDRVLPMNTGVEGGETAIKLARRWAYDVKGVPENQAKVVFAQNNFWGRTMSAISASNDKDAYGGFGPFMPGFESIPFNDIPALEEVFERDGDKIAAFMVEPIQGEAGVVVPDDGYLKRVRELCTKYNILWIADEVQTGLGRTGKMLAVDYENVKPDVLILAKALSGGMYPVSAVLTSDEVMLTIKPGQHGSTYGGNPLGCKIAMVAVDVLRDEKLPENAFKLGNKFRDEMNRMESSVIQTVRGKGLLNAIVINERPNQPNAWDICMRLADRGLLAKPTHGNIIRLTPPLCMTEAQMDECTTIIQSVFREVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAE7</accession>
    <name>A0A8K1CAE7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAE7"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000002">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035488777" description="Peptidyl-prolyl cis-trans isomerase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="36"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW59351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="211" mass="22550" checksum="1D9800AF248AE7DE" modified="2022-08-03" version="1">MANKAVRVLLLLATLCASVMVLSEAKKGPKVTNQVYFDIEVDGKDAGRVVMGLYGKTVPKTVENFRALCTGEKGDGKSGKALHYKGSSFHRIIPNFMIQGGDFTHGNGMGGESIYGEKFEDENFKLKHTGPGVLSMANAGANTNGSQFFICTVKTSWLDGRHVVFGRVIAGMDVVKAVEDMGSGSGTPKAKVVIKDSGELPESEWVAVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB05</accession>
    <name>A0A8K1CB05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB05"/>
    <dbReference type="OrthoDB" id="69983at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796:SF3">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35796">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="55697" checksum="8A698C5CF8EEE501" modified="2022-08-03" version="1">MDMHAHDALPHDIVPSVATADDEEVLQSIADVFHEGTEAVAPWEVEKSTPEELPSFEDSLDFLAALELDTPPPSDNGLFSLISPAFTGNPLPWTPVPCAPWPPGIVKSPPTSLSMDTSAPMPSNSTRMKRGRANKREELLYLRSTVSELEEKLSELQEKHAEKEEPTPDDLLIKSVWADVATRQHEQRRSAEEENAKLKMMLEEQIKVAKALEQLLRKRNNLELLSTSSTSSSGKRARIFSGKCPLDHDSILDELQGGLTHMYTQVDAMMADPRFKTSSTKTLRDIQLRSEASVGASVEIVESRVLPFDFRVTADAFWTIMLRRKHHTLLRKTYTEKIYTSTSDTLAKSFEGQLEFPRASADFRSIIVQKMFAEKNRFVFVGHMLSEPRRVLEKPMRGALMRHRGWSVIQPGPSPNTTLMQSYHVSTPELYEAVPDQRSMVGALTNFILVTVEVHLDLDIQELENHLLQNKKEVKEEEEDDKKIKMERTEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCI5</accession>
    <name>A0A8K1CCI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cilia- and flagella-associated protein 206</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_000556</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13207">
        <property type="entry name" value="AAA_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="510"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="944"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1192"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1844"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="958"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="970"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1201"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1853"/>
            <end position="1862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW60514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1896" mass="211309" checksum="08CBDCDABC3B38BF" modified="2022-08-03" version="1">MLRRHYLYREQENENSVGDGNGINLLRLWLTRRQQLLQDDQVLHFLSFFWDLAKPRHELYLSQRAYVSFFQCVAKALIQSVTASDLAAAIAQRDWLYDTEGQSSLSMEMFYESCFQLSELLLPVESDASMFASFFLELREAVTGSVPTTASYALRPFKDVLKIRGAFLQKMPPGSEHLSLIGGLAPPDIETMSLKQLLLCFNPRKISLSRKFSALFTGKPTENSEYEETEESNTSSSALAVFGSAIPLDSFPPLSSPLPPAPLLCRESDDCYDPELAVIESLTRFPALRVAVVGPPGAGKTRVAKSLAKRLDLQYFSLSSAIEEAIRTKREGDQIRTERRQEQEETIAAAVAALEAQQQEGDAAQADGEGGEAAGGEVEEGTANPKVSIPELVIDPPLGEEDDLFNDDDLDRLLQGLTLPREKALPLLVFYVRQTLLQGIGVVLDDVHPAEVDNELTIDYLISLEMSRDDAQTHITGLTLDPSSRRVYSARERTMLTECDVIVQERGLADTPRVVESTSTEDDAKPPVTASPPPDDSTVEPTEGEEQEEVPGDPVPVAVPETMTDRNEVVPPEEPTVPLRRMLQAAFGDRYSDYTERIVKAVTPTRTVVLPVLAAQAVHPIVSQCLEHITNNQQGVSRSAVSHRVIPIPLPEALDTPETSRADQLRWLLHGDWQELAATFTAERFEYGPVRAPRRLSRWQECCPVTSSSPEDEKLSLALGSPQFAAYYSGRVYLFASPEARRRFSDRTLQYLRREPPDSTVKRKLWILSSGGLTKEYAEALEQSAQTSVFSTTALVASHHSLEDEMALMQGQTLPATNAAHIVASTLQQHHDNGWILTDLMPSMEVLNILRESNCLPEHVIVLLPDTEQASGLELAKLTQWRARFGPEAASTLNSWLSEAQVPPALECPLFVAPDETITALKRLLSPLAPRVDTMEAGTLASEETGPVIFTPQPFPTTEDEAAADEDTQTESKEEQEQQRRRQCGETARFCPVSWTTKQLLIPGLPTFVASYQQHLYGFAGQSELSSFERNPVRYVPKQAGATHTVVPIILLVGVRGTELDALVTQLLEVSSSHKLALLNVDAVLTRVQSRDQAQSLLPEDKQTPRSSIYVQELKIELEALRASSSEAPDAIILSGLTDDEEPSARIPTTDFLALCYQHDIFPTLVLPLQVGENMAIERQLTQWRTSLPPARVKKAKRDDEEAENEEPEVDLETREAEERQRLQEQFTSDQETLQTTLQELHGRGIQVVWPPASTDGSSRATLKSLRNHVDMFLSSKHSLFEHSERVPLDMALQLLRSGEALVGKHGRLCPLTGEDRNTTDALLYRGRLYFPQSSQAWTRYRACPSLLVEAPSQPPLPRPTCAVVGPPGVGKTRLASSISTTFGLVYVSPDSAIEWVLQCHGGTALWTKLNQVRIAGAQADAVTMHLAICTRLRSADCQRNGWVLDDYLQSREELRRCFDVNNSIFPAVIFSLQANDMQYTKQAAEDFATKMDAWQTYRLELLHTWTSVFGAFHFRQIEPKHNSFWQITAQARVVLQEYSERLRRYTQDSRAGRPTRLEGVLRPYSIFHKQQHPAYQSFCPISLAACQYHYTWPQRREFCVEYQKTIFWLASESSAGQFCASPEEYLETTQAEMAQNLVDRAPVEASLLSLLSVSDCDFPELKGYCPVSFKNGTGDKDWSAIVKGSVFYRSSYQDQVFFFVSEEARRQFVLEPRQFIGQSLPMKLPPQLSTALLAKNCPGPIEQLLSGVLNETLLRLGSERLKYPLVSTQATACFHLGLMLKTQSKSLSDRVKAHYGARLQAFERDCHLGELLKSSKINGVTSCGPAIKGVRAVREASNAKIEVDARDEDQSIPGSQTPRTTSAERFDAITADLGSNQSPRRNILFHEYAAPPAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCM2</accession>
    <name>A0A8K1CCM2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCM2"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="455" mass="52824" checksum="0EAA49C6771F63B0" modified="2022-08-03" version="1">MQAELQHLRVLARDLEKKRDELQKQAVVPGDKTWRGVVELEAAQTKRARELNRHLRARLEEHRSVIRHLRKLIRDKLDMARDVYASLPERHSGPDLFDTFLKEIHEGYRMTDSIVDSSTWEESMNHRAWQVSTRSIEQNGRLQKVIVLQNQFWYPTSEFTSGSQVTKMKGVTKVPVRNPSRERMQAELRHLRELVRELEQKRDALEAPAPGLGEAWRKVAEYEAEMCKHAEELNVELRARLEEQIAVLERLHELIDEQMKAISDIDAGTPLKYSDPGVFERFLDDIHKGYEMTDSLSHRLDVIRREIAEKKRAQELNAQLRARLDEHIAVAERLKELIDGQLDTVRDVYANLPSNNTNPDIFSKFLGDIQVGYDTTDSIVDSVDWGEDNHLSWRVDIRSNMHNGHPQRVLELQNQFRNPLGQFVSGEGDSKSWTYTLEYLQSPAFIVDEFAAHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDB7</accession>
    <name>A0A8K1CDB7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_000945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDB7"/>
    <dbReference type="OrthoDB" id="529194at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050435">
        <property type="entry name" value="MZM1/LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749:SF1">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW60903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="128" mass="14592" checksum="FF04D9F873DC8918" modified="2022-08-03" version="1">MSLRSQVLGGYRRLLRASRETFRGDTYAIDQARLALRENFLVNREVQDEDTVHELIKGITEAEDMLRHHIVQGRQKATDDATGAPRYEVQLTDPQRNAMRKDEELTPLTDKSADEPLVINSGNVCQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDK9</accession>
    <name>A0A8K1CDK9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_013562</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDK9"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="9">
        <location>
            <begin position="152"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="179"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW61099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="573" mass="65712" checksum="5007729674F2D673" modified="2022-08-03" version="1">MAERLSSSEFKKKREIEEARKNGTLPPEQDADGNLINPHNPEYLTKRPWYLLGSAEDAGPSLKHQTLQNESHVLSIHEADDLYLRGKKRVQAAETKPRKWCKGACKNCGAMSHKTVECVERPRKVGAWKTSKDIREDEVLVDVRSQKYGKLAFDAKRDQWLGYDPKEHDRTVERYQKIEDARKQKRMDEVNKKLQKASEKNKKNKKGSDSDSDSDYDSDLQSEDEEFRDREEGPMFSERIARQGGVGGAQMMTTVRNLRIREDTAKYLRNLNPESAYYDPKTRSMRDNPNPEMNPEDTTFIGDNVVRHTGDAQKLATTQLFAWEAYAKGADIHPQATPSQAEFLRKQFEERKAALEREKSKKILDKYGGQEHLQAPPKELLLAQTENYVEYSRDGRVVKGQERAKARSKYVEDVYENNHTAVWGSWFDRREMAWGYGCCHSKVRNSYCTGEEGKQALEAAKIVNTERPMLQAVERTDKDASREGKGSMIQKRSELYGENIAPELDAKKLKKALKKAAKENAKSESDDRKRKYNSMSSYEVNAEEIEAYKLTKSRSDDPMAKLLGKDGDTLLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDL8</accession>
    <name>A0A8K1CDL8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_000983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDL8"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="686"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="33"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="202"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="429"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="782"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="793"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW60941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="816" mass="92117" checksum="B34FD57D097B0D59" modified="2022-08-03" version="1">MSDSDSGSRTTPDDLFDKAGPEDLRPGRTIVDGLQTYGPFIVVGWCAFELARRYYAQAYYVRERSPETASPTTVMARRAGIFGWLWPIYTTSDDVVFQTCGMDTLFLLRFMRMCQKIAWLGILMSGALFPVYYYGHAEGSTDAMFKMTLSHLDIDKGDGWRFTLTVVSMYLVSICTCYLLWNEFSVYVRRRHEFLSRKASQQYTIVINGLPDHLCTQQTLRNYMEVLFPKSVLYVYVAVECGDLEKLVAERVKVRNRLEHALALGAKKGERVMKRDKMFGEKNVDAIELYQDQLRNLNDAVEMEVRSILRNQAALASQMLEASLVDDEESDVPTLQTQRQNVIIVDEGRSAESAYIKGLRKRTKGVENTSIMRGAGFVTFNTLGAAQSAQQVLQASDLTEMRIEAAPHVDDVVWENLGISFNVKSYWGFISTAATTAIILFWTIPTAFVVTISKVEKLKTELKWLGRFADKNPWIEPVLQQISPLMLSIMNALAPIIFGILSKREGHASGADVQNSLLNKLVAYQWFMVFLLPILGGTFLDSLLGKSEDNQLKDPTKLVQTISEAIPAQSSFFISYLMVQMGLPTSLQLLRVPPIVKAHIYRVFAPKLTPRQRSSAWFGLAPLTMPGDIGVTDPIAQYYLVLILILVFAPVAPILCYFAAAYLFLSELVFRWSALCVHDPSPYRGAIYFPTLYRFCMGALLFSQIVMATVLGLKRTALAATFAIILPITTVLFHLIAWKRFPRAALNLPLDECVMLDKRRHRQLDDLEKVLEDVYRQPAMAERHPIDPDYPNLASNPDGANQLSSPVKEYPDKEYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDZ3</accession>
    <name>A0A8K1CDZ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDZ3"/>
    <dbReference type="OrthoDB" id="167943at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="37278" checksum="F32499587E8BEAF7" modified="2022-08-03" version="1">MDSSDRSGVPPAPKNDSQHEQHRNARRRRPYDPTLAITSLAEAHGYESGEDTIRTASDGTLIPRSSRKRYFPRAQRRFRDRLQLLDERLRLDVNSLKQEILDLQLQHRLIDTRHRVQRHARTDAAVRVVQEYFEAFRSGIAGADDPKDLKGRQERFLADNMDENMRFGRYRDGITILMEQWRRYTLCHREFQVRLLHIDTSGAVSPTMPIVRADAMISGYITHETMSTVFPRVIELYPHLAALMVGALIEYPSLVTFHFNADGRISELDGEVDFVLPLAGVLGSLRDAALVLSASTIHEQCLIGSISTSRESGLRTVATTGSLFEFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEG8</accession>
    <name>A0A8K1CEG8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cullin-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEG8"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000014">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="9">
        <location>
            <begin position="422"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="809" mass="93106" checksum="4E5DAA7307167A9F" modified="2022-08-03" version="1">MRFYRHGNDIEAAAKETSPRSSGNIGHATCGRLFSVNMSLLKASTVNLEKLWDDIQPPLVSLVSGAPQTMTNEKWLEMYTGIYKICTSPGVPQAEMLFFRLRGLLVEHVERIHHELRDIAGEIEFLKRYYTSFQSFSTGVTYISELFRYLNRYWITYSHCETGQAPVPGVYPVTELALHIWHDIAFSRLKKKLVSSVMYAFRAARDERSEFFEDGEHISNIVETYFALGLVKKDPMALYKDDLEEPFLAETASYYSALAKTLLSKVSISEYLQEVEILCKQEQRRCEGCMHRTTVTQARQTCCRVLVDEHAERICEDAETFLVNNQTQDLHRLFSLFSELPKEQALISFKNILKKYIEKRGLDVVRKFEHEDAAKNPEGYIEALVQVRNKYFELIKDAFGFHALMRTALDQACRTFANSHPRLPELLAKYTHYLMTHDKKRGQMKSPSKAARHAISPHTPGSLSPLLMEESLEKKIENIGVVFCLIDDKDVFKKYYAKFLAKRLIKGTSVANDLEVLLIQKLRDICGCDFVSKLQKMLKDKLLSKELLETFDTWLTENEAKLESNQDAITFHRSLSYHCDVLTAGAWPISAVVTDSQLLLPRLVDEHVQLFSKFYTDRSTGRKLLWVHHLSFGILQANCFDRRYEFSLSFYQMLILMQYNEADTLSESALVEQTNIPIKDLKHHLASLVKAHIIREGDEGNFMLDFSFSSKKTRISAVPSSPVESPKVAKATTREVEEDRKMALQAAIVRVMKTRRDILDSQLHNEVAEMLQSQFVPTSTALKQNIEILIQKEYLRRHESQQSRLLYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEX0</accession>
    <name>A0A8K1CEX0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012741</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEX0"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953">
        <property type="entry name" value="KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20953:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="3">
        <location>
            <begin position="398"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="607" mass="67772" checksum="DF707080399E610A" modified="2022-08-03" version="1">MALCEHFDRFSSADTQQKLLRSLLRRHTVVGVHFLLDGSSSERRLTTVTIVWPPGSFSPPWIIHQDFIGPALFVALLETLFLHSKAVKVVHNILEAAYWLSTHGFRVDERVRNVVDLQLFYELVVAPDVRNASLETIVAHCNVHASTSSHREALRRQVQQDPQSWSESIDSLQRIERAVECAQLSIACFEQGVSTQCSPEIRTLLFEYTARRWQFALPNDGHAMIWFDPAKNYQARSVECLATSVLQLKRIAPALEFECDLAPLLAVLPSRFQDAVMAIQDFEQDVAMLCLDVGRLPHAYTVTNRRVLLTPQPSSRIPAKLARRAVVTAEEVSDVVKMLGGEGHVQDDNRIGVDRQLHRISVMRSKTQEIYGLTLRVGRTLMHASNMLLDLLLSEEHRQKSVLFLGRPGSGKTTMIRDVTRCISESGENVCIIDTSNEIGGDGLVPHPCIGWARRMMVRSLDEQASVMVECVQNHTVETLVVDEIGRKNEVLAAGTVRQRGPRLIASAHGDFRSLIRNSDLKGLIGGVQSVTVGDAEAKKKPGLGKVQSQRSGAPIFDVIVELDEVCRGRCRIIWNVANAVDDVLSGQPYAYETREQSTKFRGIRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEX9</accession>
    <name>A0A8K1CEX9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Poli38472_009707</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEX9"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000009">
        <property type="entry name" value="Fatty oxidation complex, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052242">
        <property type="entry name" value="Mito_3-hydroxyacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561:SF3">
        <property type="entry name" value="HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="15">
        <location>
            <begin position="39"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="228"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TMW62214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="331" mass="36024" checksum="0D759798D578E485" modified="2022-08-03" version="1">MLRHSLRSSLSTARRASAVAANFQLTRAFASGNDIEFKKVGMVGLGLMGHGIAQTAASAGFQVVALDMNQKGLDAGMKRIEGSLTKIQARNVKKGTISEEDAQKKIAETLALITPTTKTEDLADCDLVIEAIVENVDVKKEFYANLAKIVKPSAIFASNTSSLAISDFAGSSGRPEKVVGLHFFNPVQIMKLVEVVRTDDTDPAVFEACKQWVHAIGKHPVSCVDTPGFIVNRLLVPYLAQAIAMYERGDATKEDIDVSMQFGAGHPMGPITLADYVGLDTTLFILEGWVRDHPNEPAFFVPEIVRQKVKEGKLGRKTGEGFYKWDGDKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFN0</accession>
    <name>A0A8K1CFN0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFN0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18424" checksum="1D28ABAFC30740AA" modified="2022-08-03" version="1">MTTLQNITWVDFQDPHDPRMPPLLPGTIRILNTLPSRLTDMNNAALILQISDQYALHEALALPEAPIPQGRDVEASVAAYRAWIIRQADRDREGQGRLIQNDDAICFAPIGFGCSRAVQCAWGNQLWQVKQRVAGMSDFGSVFRLWKKGRKTATIAWLRGGLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFY7</accession>
    <name>A0A8K1CFY7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009619</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFY7"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050086">
        <property type="entry name" value="MetN_ABC_transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166">
        <property type="entry name" value="AMINO ACID IMPORT ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF9">
        <property type="entry name" value="GLUTAMATE_ASPARTATE IMPORT ATP-BINDING PROTEIN GLTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="336"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="543" mass="60932" checksum="BE68BB3EA5FEFBE2" modified="2022-08-03" version="1">MATMTRRFGVTPRVLRASRRASTQSIRFSVASRFHSSSAHPRRPHIRDDPSDSVESTEGPKTPLLTVPPAYTLHDNEIHCFLGVNGSGKSKLLQRIQDVAAAMPRSSQSPRVGTLSFEAHRAFVGEHGDRVVAEVLGGVGSPTARDLIVRLGLYPVWESKVRHLSTGEVRKVMLAVALLKVPRSTVLIMDQPFDGLDVAARKQLEWMLGQLTRGFTRLLVDFGGRNEAFAYKTQVLLVANRLEQVFPEILTHVVLKRKDNESLESEKKEDAVEIVQWEDPEKPESMLARLRAFFENEATQHGTELAEEDVKTLVRRLYSSKAEPSSDGASTRQIAIELHEVSIAYGRRLLLEDVVFKRHRHEHWALLGPNGSGKSSLMRVLTQSDGHGQVGGTVRVHGERIAVVSTDQHLEMLSRPEWKDRTALDWLQLNAQDSERVEVVTELLGISSNLLPRRFNELSQGEQKLIQIASALVGRPDVLILDEITHGLDMWNRARVLQVINAVGVEASTQTHLILITHHEDEIVECFQSVFEIQDQSLVERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGX5</accession>
    <name>A0A8K1CGX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGX5"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="20993" checksum="F56CCBC6DAF690B8" modified="2022-08-03" version="1">MVNVAIVYYSTYGHIVKLAEAVKEGANKVEGVTATIYQVPETLSEDVLNKMHAPPKADYPIATPDTLKEADGILFGFPTRFGSQPAQVKSFFDSTGALWATGALVGKAAGLFFSTGSLGGGQETTAFSTLPFFAHQGLTFVPLGYRSPLLSNLKEVHGGSPWGAGVLAGADGSRQPSELELEVAKVQGESFARVAKKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHQ6</accession>
    <name>A0A8K1CHQ6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_005614</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHQ6"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="294" mass="32823" checksum="EED4374F252CEEFA" modified="2022-08-03" version="1">MSAPVLKLDYMRAGARGSTLSYGGAMTGMHLPFAPAMDAIDAPLNLQNDQFASGFLLPAVPDPAEYARTHLKTKYGEDNEQALQFEKGTTTLAFIYKGGICVAVDSRSTQGAFIASGKVKKINPINEYILATLAGTAADCQYWQRNLAVQCRMYELRNRHRISVRAASKLIANTTNYYKRYGMSIGMMMMGYDNGEPVLYYIDDEGSRMRASDKVPKFSVGSGSTYAYGVLDNNWRMDLTDEEAVELGKRAIYHATHRDSYSGGFCNVYLFKKEGFEHVVHQDVDEMHDHSRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIA4</accession>
    <name>A0A8K1CIA4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014817</name>
        <name evidence="3" type="ORF">Poli38472_014818</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000044">
        <property type="protein sequence ID" value="TMW63908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIA4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="38647" checksum="6673CBF4BA79AD63" modified="2022-08-03" version="1">MLPHANAAAFASPIPVTSVCAPCMPDCLASNTFEVRSMLRWRPTQLTFVSMFDDEVELYYGPSSDRTTMVRIKRSATEPNAIRLKEKPTKCEFSLTIPKRLTKLRLRAASPREYALWVHVIRAALGGPSITVQSIRALEAKATPGYASVFMHHLARVPTQASSVATAAESSPSPSPSPSPPSTSSTSSTSSVRTPVGPIDPIDPVDPVDPVDPVDPVEGLDLASLVSPLRSPLSWSVTPLTPSSSSSSSPRSSLLSSRSRSSSVSSLLSSLLTTSPIASSRGSFEFPELHVELDVELDVEVDVELDVEVDSPTSSAGSCDWDQELEYALATYQTTIENARYYEPLHHKTSRISLYTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ95</accession>
    <name>A0A8K1CJ95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_011521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ95"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="208"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW64641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="505" mass="55506" checksum="CB023F92D2124E61" modified="2022-08-03" version="1">MDADSTQDLGNCAVRLGDIAEVVLLDTPANSFRVHTALGRQIVFQYRGEDDQAHQQTRYNASQWCDYLQTLSQYARGNEERIEYPSRQDNSYFHEVSTKSSRRQELLQHMTHAINKNDVFGLKELLGIEQRSNNELRDGDGNSLLGMALKAGANKDIIEALIEARIDCNAQNSEGESPLLLAAASGDLEILRLLLDAENIDINQRCKMGTSVVHAAANAGEAAALQQLCDTGAVLSVADDVGWTAMHYAAVCVSGVGPLRLLCELVPELIDSQCAEGNTALHIAAGYGCEDNVRALLETAANPHILNYDKQTAYHVALHNNHVACAVAIHEYMDTPRDVYEQSAQAPRAVYTEETRSAELSTGRVATSENHAYTFSAWIRATTEDGLEYFYNSITGESTWHRPDELEQNSAQPPPAPTTSQHSYVEEIFSFAEPGQKLPLCMIPLVSPLVSLDDPTAATKLDAQRKKARERRRSKVSKQRQRSHSSDPSSDPVQAVDTTSGYTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJP3</accession>
    <name>A0A8K1CJP3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJP3"/>
    <dbReference type="OrthoDB" id="418349at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF91">
        <property type="entry name" value="DUAL-SPECIFICITY RNA PSEUDOURIDINE SYNTHASE RLUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="4">
        <location>
            <begin position="187"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW64173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="386" mass="43637" checksum="C16A26D46B200521" modified="2022-08-03" version="1">MKLMRPAKRVKRAEDVGDDDTLSTPAERDGQGQLLQEMKEMLAHLMQSFSLAATDEVGNEKLLKLRSLAHIRAGYYTSDIAVRLYHQYIRPRQKTALETIARDGFESSEAFAAACVERLAIYLDHQSARSRHIRRVMLSDKSMQDKGILPDRLVVVIHQVAREVTNGGDVASRLKTRLQVLYHDECVLVINKPANFLSVDGTTPDEESVQGIVRQYYPDARMVHRLDFETSGLLAIALTKTASQALNRQFRERTVDKSYTARVYKSVEKDSGCIKLRMEPSTSERLVQNVVEEGGAETHTEWRVLERGQCDTLMELKPVTGKTHQLRVHMQWLGHPILGDSLYSPDIVQPLAPRLLLHATELSFTHPLTQVRVTIRSECPLTNASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJP6</accession>
    <name>A0A8K1CJP6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WLGC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJP6"/>
    <dbReference type="OrthoDB" id="166170at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058256">
        <property type="entry name" value="WLGC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26605">
        <property type="entry name" value="WLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="WLGC" evidence="2">
        <location>
            <begin position="315"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="380" mass="43010" checksum="451608BD49987079" modified="2022-08-03" version="1">MRTIFHLVENHRGIPNLHTSRESQPSLKRLFITKARQRQSLQNLFISSVFFCVGVGIFVHSIVAVTSTKHVCAPHPHCAVMSYQWNVNAEYCSCIVFVNRLTRVTTFNDWENPRDATTDLAALAKSGHLWITQIVNRALPTFPEELRQFHGMEQVIRIYSKTLRIPDWAIEWKALKYLHIEGDFTANRLTYMPDDLFAEMHDLAFLHLGSLTSLNLLVFADAIQVYKLPSLANLKKLQQFTIVFRNPVCCNGFITGKCDLSDFQCKPRVDKPVVQCTDERIPREELAMVDKVKVVLCSQNQKTDLKDSRPTVATTDEACGGVMYKQCTTPSGATGICYTARMMVISCDAAAGYDKMRRLQIARGVGEPCDPRVEAWLGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK25</accession>
    <name>A0A8K1CK25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK25"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="345" mass="39140" checksum="DB72492643047EC1" modified="2022-08-03" version="1">MGTSPRPKRPRSTYEARRMERASLQHELQTLTKRLEQLQAEHPALVISKAQRACAENALLRQSLFERDLVTARTVSLLSHEMAAHPRNPLATPICMPVDLEERRRVLAALRPAKLAWATRFLLERSRFTPRDRQFRETESFITPQGDSIVMQFDVMPFYNVLSTQQVVNALQLALAHQEYAFWEHMGLTTIGETDDNATSPASQVRYFSTTPGGVDVERNLVIFSSSKAPNAHVQQDHGVVAVDFVDQDLLHPYSPAQRVRMDVSAAVLVCEQPKTPANASGSADVCVIRWAFARLHRPQCKLSPEKTQELLDLHPRWGEALRRAMQEYILQNSLARENTDSPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK59</accession>
    <name>A0A8K1CK59_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK59"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="200" mass="21049" checksum="2E335D0E16D3D6D3" modified="2022-08-03" version="1">MTRLAIVYYSMYGHVAKLANAVKQGTKLVPGVETKIYQVAETLPQEILSKMGAPPKPDHPIASPDVLKEADGILFGMPTRFGMVPSQMKGLFDACGGLWAKGELIGKPAGFFFSTGSIGGGQETTAMTSTPFLAHHGMVYVPLGYRSPLQGTLDEIHGGSPWGAGTLAGGDGSRQPSDLELDIAKLQGQSFAEIAKKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKG1</accession>
    <name>A0A8K1CKG1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009067</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKG1"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd22981">
        <property type="entry name" value="DD_TbAK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000120">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000133">
        <property type="entry name" value="Camp-dependent protein kinase type i regulatory subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="155"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="273"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="44843" checksum="B8BD007D00016C2E" modified="2022-08-03" version="1">MADAEGVQQELQDYLQKKGINTLFINLVESLLLAKPENPVLHIIQYLQSNFPDQALPKKTVLHPGNKDVDPAVSPRQHTNHYSDESESEDDEESDAVGEINEKPAPPKPIVKGRRTSVSAETIDPHSAKQFERVIHPKSDEERQQITKMVAENILFKSLDEKQHEIVLDAMFPKDFEPGETIIKQGDDGDNFYILESGVCEVYKDEVLVQTCTNSMSFGELALMYNAPRAATVKAIEKSKVWALDRQTFKYIIMETTLKKRESHKGFIERVPLLESLSEYERLTVADALKTETFSDGEVIITQGDEGNMFYIIEEGTAACSKQLSPDEPPVFMGNLTCGAYFGEIALLTTRPRQATVTATGKVKCLTLDRKTFKRVMGPLEDILKRNIDKYNSVIANNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM57</accession>
    <name>A0A8K1CM57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 9">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="9">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 9"/>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM57"/>
    <dbReference type="OrthoDB" id="543511at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017172">
        <property type="term" value="F:cysteine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019448">
        <property type="term" value="P:L-cysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="7">
        <location>
            <begin position="96"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="192" mass="22242" checksum="90A4ACC4E1FEE86C" modified="2022-08-03" version="1">MTTTKNAMTLANLVESIETLLLEEPEVPLKDKLKIQTLLEAYPVNMHELKPFAHFDPSRNYTRNLISTDHETYALMLICWNRGKYSPIHDHPSDGCWVKCIQGHVNEVRYERRGERLVETSNIVLTDGVTYMDDSLGFHKVGNPREDMDSITMHLYAPPYEKCRIWFDPENAEKSSVAVTTYFSEFGERIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM69</accession>
    <name>A0A8K1CM69_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008271</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM69"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056452">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 3-BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23546">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPO_IA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="293"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="455"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1123"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1124"/>
            <end position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1152" mass="125972" checksum="16274AACA8B7D31A" modified="2022-08-03" version="1">MEPSSTNAAAARTASAPVTSGASGDASAAATKKPRGPKKTGPKVAWAKKEEGDNASKAATGEGEHQAKRPPRQEKKSEGKGGRKPKDKSQETVVTVDEEGKAKTPQKKEGEGKPKSKPKKDGEGKAKAAPKQEGEGKAESKPKKESKPKTKKEKPAQANESSNANEPAASQQASSESNNSNPKKKKTGMSDDKVATTESKREIPKKNDQAGKNESKKGNDNGKHDKKAAAKDPKGKKQQDKSSAGNASQPSSKQSKKPASAPVPKTNSAADLNAMLSLVRRGGLSQGASDPITVLMVAEKPSIADSIAKALATGPYNFRGGKTPVHEFPGYFEGQPCTYKVTSVTGHIYSCDFPPEYSSWDTVEPVTLFTAPTMKKMESPGVFRQLQTESKGADVLVLWLDCDREGENICFEVIDATKSKMKKHFHGDPIILRAKFSAVNKSDIRKALENLILPNENEALSVDARQEMDLKVGVAFSRFQTRYFQGRYGDLDSSLVSYGPCQTPTLGFCVDRHDEIESFVPKAFWALDVELQKGGNTVKLEWDRSRLFDQEAVVAFHNSVKDDGMMKVTKVKKSETTRPRPTPLNTVNLLQHASKTLGIGPFTTMQVAERLYLQGYISYPRTESTSYPDSYDIRGTLGQHSTNPYWGHYVQDLLRAGYQRPKKGVDVGDHPPITPVRSASPNDLPGDMGRVYDFIARYFIATVSPDAKLLATKVNLTCAGETFSVSGHQVINKGFTEIMVSTAVGDTYLPEFNEEELIPLSSINVRKGFTSPPGYLTEAELIGLMEKHGIGTDASIPAHINNICERNYVQLGAGRTLVPTALGIVLVRGYHKVDPELVLPKVRASIEDQCTRIAKGIATKTQVLETALAMFKNKFEAFVEKIALMDALFLTTFSPLEATGKPLSKCGKCSRYMKYVSHRPQRLHCAICDETYNLPQNGTIKLFKELRCPLDNFELVLFSLGNSERAMGKSYPLCPYCFNHPPYENMSQMGCNACLHPTCKHSLTFNGVFPCPRALDTPDAPPCTGTMVLDATSKPNWKMACNTCHVLVKFQSAVPIHNLKTKHDQDCPDCGSTLLEVTFHKDKTPLKDKATEYVGCILCDDYLNGLTELKKGRMKHIDLVKNRNSGRRGRGRGRGRGRGGGKKGGLLSVYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMG0</accession>
    <name>A0A8K1CMG0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMG0"/>
    <dbReference type="OrthoDB" id="10265294at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004846">
        <property type="entry name" value="PRK06197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="328" mass="35337" checksum="0362C1940A2BDFE3" modified="2022-08-03" version="1">MSSYSKQAADAVPSNWDAYHIPSQKDKVAIVTGGNSGVGYETALELVRKGAQVVLGCRNEGRGAEAVKKIQAEVADAPEAGSVAFIKLDMADLSTVKSFADEFRKTHNRLDLLINNAGVSGVQYGVTVDGFESHIGINHLGPFALTAQLFDLLKQSPHARIVNVSSMKHRSAKLDVNKLMLNEDNYNGDTAYDNSKLGNILFTFELTRRCEANGISNILAVASHPGASKTNILVEPTTNNKFWDKMKWKFLSILPVYQPASMGALPSLYAATAPGVKSGEFYGPGGFMSLGGHPALEDPSEDSKSATTALKLWEVSEQLTKVSFPITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNA9</accession>
    <name>A0A8K1CNA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNA9"/>
    <dbReference type="OrthoDB" id="156202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035455100" description="Apple domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="50"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="209"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="278" mass="29272" checksum="0D87C0526D5F2665" modified="2022-08-03" version="1">MKLLATISLVIAITATATTVDASSLRSVNDTERHLAKMEYMAAMAPTPNCVIEHGFDYIGYDIKSVQGQPVENCCQACATTDGCRAYSWTNQNGGTCWLKSGRGEIVSNPNVKSALFSTTANNNTTCQLANDLDYVGNDIGRASASDAGQCCDICQKRSGCRAYTWTGQDGGTCWLKSKRGETTYKAGAKSAEAYPVDSGNNSPPPAKCDLVKDVDFVGNDIGSPEPGATADQCCTICKSRPACKAFTWTNQNGGTCYLKNGVSSQASKPGAVSSVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNG0</accession>
    <name>A0A8K1CNG0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_008125</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNG0"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="301"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="345"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="429"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="595" mass="66782" checksum="C38D8E03CC6B906E" modified="2022-08-03" version="1">MEALVGYASSDDDEPRTSKHEGVSSPTDTFALPVVNSAPIVAVADPYMAASAQQLAAASSSKLSVNLPIDSTLAAYHGPENAYARPGQSNPALIGGGKEIVTGVVERADLDSFSFDAQYHTYNYNHTGMLPNKQQAPGTAASDSIVSHADDNVFTKRTTSKKGQKPQKTFNDEFGNPETDGIWAPYKEKSVLTDVEADTLTEEQEKIRQERIQAKKRKAEERSNTEYHEDMDFDRMVEKKISHLLPARLKAGQEAMPGRSEFLDAQEYDYQGRSWVEPPRSLKPDDGDHQVFLPKKCIHKWTGHTKGVQAIELFPKYGHLLLSGSMDNTVRIWDVYNERKCKRVYEGHSGAIRGIQFSNDGRQFLTCSFDRFIQLWDTETGQVVKSFTNRRVPYCIKFYPEDNNQFVIGDSNNMIVQFDARSGEIVQEYNHHLQAVNSVTFVDDNRRFVSTSDDKKILIWDWGIPVPIKYISEPSMQSMPAVALHPSGGFFAGQSLNNQIDVYTARDKFKICRKKTFKGHSNAGYACQLGYSPNGQFLVSGDGEGKLCVWDWKSTKMYKKLKAHDRGPCMGVAWHPLEPSQVVTCGWDGLIKLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNK3</accession>
    <name>A0A8K1CNK3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012031</name>
        <name evidence="10" type="ORF">Poli38472_012034</name>
        <name evidence="11" type="ORF">Poli38472_012037</name>
        <name evidence="12" type="ORF">Poli38472_012040</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNK3"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="123"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW66918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW66921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="337" mass="37836" checksum="BBBADC4DEB87FED8" modified="2022-08-03" version="1">MVVTGSAVLAKPQKEPAFSKKHVPSGLSTLFKPQPEMIMGVWAAWVILFIFFHVVVWVDPVYKFVVTDWEPFLYTLVGIEAVFLLTWFRLATVCPSDPGVIRTFQVDITQMLANAATGVVPPEASYCRTCMIRKPIRSKHCAQCGVCVARMDHHCGWINRCVGYGNHRLFVCFLLLHIIVVVGFVLLAGVVFQLPAFPPARQLDATLGSSVMRVWMQVPDLVADHLLALMVFLWGIGTVIGLSFMAVQHLGNMARNLTVNESINWRRYPYLKADPKNNSKAADKLPRLLNPFDKGGWHNTLEFWTRSGSSALDYRTVFRLPNAVDEPEEPIINVQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNR6</accession>
    <name>A0A8K1CNR6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_012142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNR6"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="264"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="402" mass="45585" checksum="BE3B95DD3893C5B5" modified="2022-08-03" version="1">MASSDHPVFQRLSRLQLVARRRNIGYQTLVFQSSEPRTERCKHCGRQFSTDWKAFLCHVCGLWVCQPCSCVLERERELQYITFIRSCIDCVSMLNKWSDADLFTEFATHPWVVSSSKKQISLTLADTLRIKKESRHAVLTVLKYLGKAVDPDALYLDTIEEDEWIAATTECNVSHPSDVDVNSLETPTERVHHLVQLCFEVEIPEVPLGDCVFAESDGTRHYALRYDDPDEPSDAPCVPDEDERLRTIEEYGSITRSLNTPLMQLICALVAKELDVWSAYITMVKDKTQYLVAAPPGCPCSMALKRSQSFCAYALASPRPFMVRDASMDIRFRNLDVVRGGSHLVFYIAFPIVDENGKTVALLCALDSKPHKSITTMQYSVMQRLAAMTSSFLQKIVDQCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNZ0</accession>
    <name>A0A8K1CNZ0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E1 ubiquitin-activating enzyme</fullName>
            <ecNumber evidence="4">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003866</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="4"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNZ0"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000015">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2660:FF:000005">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000001">
        <property type="entry name" value="ubiquitin-like modifier-activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="11">
        <location>
            <begin position="952"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW66101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1117" mass="125356" checksum="45DB9174EA26D412" modified="2022-08-03" version="1">MDATKQLETDAGFMDKYSRQIGAFGLETMAKLVKLKVLVVGLQGVGMECAKNLILAGPGAITLHDDTPAEIKDLGSNFFLAEEDVGEPRASAVAHKLAELNKMVTVSVHKGELTEEVVGAHNVVVFSHTKRSELLKWNHFCRAQSPAIGFILCDIRGAMGYTFTDFGDQFVTHDATGEAPITRIITDITNDKDGMLSILGPDEDGKMHEMPDSDHDGWVEISEVEGMTLKSDPNKNINNMGPWRIKFANKKMFRNGKQVEVFDPYRIKIGDTSDFTPYLGGGILTQHKKPFPQKFYSLEESLLNPVYPGEYGLMFTDGAKFGRAEQLHIAVWSLLEFEERNGRLPQPHHDDDAAEVVAIAKEGLRHLSELTDGKEAFKVDELDEDVVTQAALYAVVDLQPLAAFFGGIVAQEIVKFTGKFTPLKQWLHFDAFEVLPDERPTDATPIGSRYDHIITTYGLEFHQKLSNIRTFLVGCGALGCEYLKNFAMVGVACGEKGHVTVTDNDRIEVSNLNRQFLFREHNVGQPKSVAATNAVKVMNASLKVKALEQLVAPHTENVFDEDFWTDLDVVTNALDNVKARLYVDSKCVFHKLPLLESGTLGTKCNVQVVIPYQTQSYADGPKDAEDDNIPMCTLRNFPSLIEHCIEWSRAQFEDLFVVPAAEAKKFLGDRQAYLTKIKQATIDNPNEKVGQAATAQELERLRTLRKTLEQGRGMTFEKCVQLALDLLTALFRDRILQLIHNFPEDHMTNSGERFWSGAKRFPQAILEFDPEDTLQLNFVRSTANILAVCFGLQPPPEHQLVPSDSEWRDPSTFAHLSKEYDIPEWNPTDEKIAADSDEIKRLEEERAKSVTDTDRDELVNLLNELEELDLNGLDFEPADFEKDQDLNFHIDFVYAASNLRAHNYKIRQASRHKCKMIAGKIIPAIATTTASVTGLAMLEMLKLVQQKKLDAFKDSSNSLGLNMYLMQEPASPEKAKDEYDVVEMAEVKCKPSGFTKWDSTIIEVSSQATLAEFLQVFKDKTELNCDLLFHAVAEAGPSNDDVRFKTVSGLMLYNRNEYAKSLKELYAEQLDLPLRAWVETRYLGLVDCSRKYIEFQTSCSDDNGDVFRVPTVVCKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ08</accession>
    <name>A0A8K1CQ08_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elicitin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ08"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035431017" description="Elicitin-like protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="118"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW67405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="24231" checksum="A0130035F4E46310" modified="2022-08-03" version="1">MRVLALSLAVVAAALSTVQVDAASACNATENAALDTLIEPLKGLLAACKADTGYVMYPFTAYPANESQQIHVCSGRSCPTVYGKLLEDDKDKLPDCLVTIGSTPMTVTKFLGSICDKRPDTPVPSPTNTTSPAPTPTTATPKPKPSTTIPTPSSSKKPVASGSTSSSLEADSKSSGSSEEKDPEESSSSQDTDIDVTIPGEQSEPPSNPDVPLPSAATTVYVASMVAAVAGVAALTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ31</accession>
    <name>A0A8K1CQ31_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ31"/>
    <dbReference type="OrthoDB" id="168304at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="574" mass="64681" checksum="FD9F87595401BD62" modified="2022-08-03" version="1">MVMGRSSNIGTLTFNDFQWLDHYILVDVTRLKISDVHHVSVFCSPGLWAIDPLHSLACQMVTTPYSSSNQVFPQISSQPETPEHRVAAYINRVLKSVYETEQPDKITPNLQSQSTRRGGAAFASSNHHVNLSDLAHRGHWTMDGFATLLEYISPTSSSDQTIGKVLGGWHDPKPAGLPPTLNAFSSEPRDVAANVRAFADYLRVRHFSRLNKASFADALTASLLMYLPDTLQVVRNNVVHNEILQVASQVLPDAIDLQGELIRWGRVIKRRFIMGNMQALPVAHIKENLSEREQAEHLINPRTYGEVLERLVIGQQQLFHRQEQIMSMLQDLMRAPRSFECSQSHETTAPSPSKVKKAKAINALAKLQQAKLWPESLSTLKERALSDVLIQVFLVQLHHLLKETGNRAQTDVIKAVDIAEQLADIRSIPPYPDAGDSHRQKEWMDTMRAMANEIERLVLECLEAEKASDPTRQRKRKHTAYINGIVRAWGRRQKKRQRLPSREGGSNSQPSSSQLIAMKDNMAALRQEYTVTQQQEMAAFVMQQVDAAIRERDANGKAAEVADVSDIKDEEMMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ74</accession>
    <name>A0A8K1CQ74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_014013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="628"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="859"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1338"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1374"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1439"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="1483"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1039"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1179"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1255"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1050"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1196"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1259"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1516" mass="171380" checksum="0648D9E75BC9E76D" modified="2022-08-03" version="1">MSAALLQYQACLGILVRLQLEDLTSLKQDFDRVGRGLSLEEFVSVMLDRVSWEMENVISFIQDLVELFAQVDVNGDGTMEWEEFTSAIIEGGMGTTSDEMDWRDLQYEEHAAFSDVLNRPPKRVQYVGEVKRLLVHDNSRPVVEIIEPTTLYPIENDDASKAESTASTDAATFVPTLTIANKFHPLCYVAGYRRDQDDVRSERSPVQALKYLSQVDLIAVSGGDLKLTFWSSTILTAASTSALETPSPLVIVHTPRPQRVLEWNASTSHLYSISADLIISVWHVRREKQHDTKSKCEVSLVTTLKRHTDLLQDLLVLNDDVLLSCGMDSAIFLWDTQTLQVKATRQGHRRGVRLLAKLSDQLFLSTGFECEVLGWDINVLATAPVFKLWGHNAPVCCIQLIPCGLTEKRSTTDAATVGWVGDQAITVDDDGWFKWWNLANITSVENNDLEQNASRCLQTFRLGSDKYPWHAHSLAVLNNGQSILATGIHKLKLLHRTRLKPRVLPSSVVLYNSLFFTILTTTDREIRIWDAKSGTLLRTYRNISPSDITCVDLDARQRKIVVGTQRGELIVLNYLNGAVLKTWMPHQLTVSALIFCKEDACVLTASWDRSLRLYDDNASANTLLRCVTDAHDADIKALTYCYAMSLVATGSADGVIKIWDYIYFLLEVTCSTSTYLLPMSDVVALEFVDPYPLLVSGHENGTVCFWHVSPSQPSVLLGHYAPFLRDPTLVVTTKASQYEDETRGGIASLRVHYDESGGELLADGIRKGRFLVVLGSLDGQVYVDDMTQLIASAHLRAIREESMPSNHHGSYNPRRRFIRHGKNAKRLKNHVKHHEHMGIEASPDHPPAPTDAITTLFKWKAHQGSVRYLQVVDDPLTLLSCSHDRSVKVWRLDGGLQGYLVGTQSSGPGWNWEIDTQRVAELKREQAQEIWDKMRDAKLKLLTQRNTLAKLRLRQQRRTSLGMASTAALGVTAEQLAHLQGMNDEGEKKKTTITSSEAERLFQQLQGQVTWQQSDFQLARQEAWERERKKFHKRMKRIMKQKKATSAENQVDDEEHEEEDSVLRDLKPQEELLDPATTLLPSDLNSSVQPLPFDDKGNWAIGSLNRERQMYSHFHHENTRRGQKSVLLGSGKLRRSESTAAIDLTPSSFLLERLGESCVIQTNSTKAIRAIKTKPKKTKALRAVQSLPELPLPRGDDEEDENQDTVDDKQPRVLKRQLLVPQQSIRELFQQFDHVQKQHESEKATIHRASKLLTGKLGSRSERALSSLHEDDSKDETATSPTRAKPKPKSAQARTKKASLSDVVVTRRKALETKEKKQRLRSDAALMRLERFGPYPRDDVVNIYRTFLKIDKDGSGTITLRELVDGAGLFGSTHLRDNIISIFNSIDQDQSGHIDLRELSGAVFNEAPSDVLHDMERFYKLLESAERAKKTKKKQLTPEQVAEVTQLFHLYDADRNGDIDVDELLTALRYNEKFYDDDDAQGITKEDVERIIARFDVNTNATLDLHEFMELFREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQH8</accession>
    <name>A0A8K1CQH8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_012244</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQH8"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000117">
        <property type="entry name" value="Probable papain cysteine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463514" description="Peptidase C1A papain C-terminal domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="6">
        <location>
            <begin position="55"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47359" checksum="596927F8D480856C" modified="2022-08-03" version="1">MLRSHALAVVAVALLAFVDAKKVCTRTFKDREHLHPKVHTLPVLNDEQVLELSSFPSKFDWCDQGYCTPSWNQHIPQYCGSCFAHGALSAAQDRIKILHKKQGYEGPDVMLGRQSFLNCAPAHGLSDGCGGGEPSDVFEFMHHYGLPDESCLPYNATDHTKFTHTNGTCPPEGYCMNCIHIPGGPDGPSCFPVKTVVRYRAKEYGRVTGEHAIMKELLNGPVTCGIACSDEFVFNYTAGVFEDKTGFVDIDHDVEIVGWGEEDGVKYWNVRNSWGTYWGMNGFFKIVRGKNNLGIEADCHYVIPDISDEELVFTEKPIYGGSHWGIVPFSKDEAKLHPVASTDDIVFSSLPLTSQELPEKNDTDDDDEITIPATRDHSMGAAGGNNHDFDPPNYHMMAGFLAFTIFGAAIGAGISSLTARRMRYHRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQI7</accession>
    <name>A0A8K1CQI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin polyglutamylase TTLL1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007629</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin polyglutamylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQI7"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF31">
        <property type="entry name" value="POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="49143" checksum="5C1D8DD78D09EAB9" modified="2022-08-03" version="1">MASRSSTVGKFKWRVDTEKNVVTWNFERRGWVKTDADDWNIYWASKTSIKTMFNPETGLRLVDGQYVNHFPNHYELTRKDLMVKNIKRYKKDVLAATTNTPQSSTSGSSVSGIAAPLSGNNSSDITASGYDFLPTTYTLPADYSLFVEEFRRNPNMMWIMKPCSKAQGKGIFIINKLSQTKKWANQRWTNMPIKDGYVVSRYIDNPLLVGGKKFDLRMYVLVLSYRPLQALVYREGFARFCNVKYSAAVNDMDNPFMHLTNVAVQKNNEDYNSHHGGKWNIKNLLLYVESTRGRNTGEKLLQDIHAVMLHALRAVQNVIINDQHCFECYGYDIIIDDNLKPWLVEVNASPSLTTTTTDDRNMKSRLLRDVLELAVVNDAPDQRRSIQPPVLSSTNGFQWLINEAALLEADRQKEQQKKNARKSVTQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR95</accession>
    <name>A0A8K1CR95_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR95"/>
    <dbReference type="OrthoDB" id="62673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="533" mass="60250" checksum="C4DACC07C5480222" modified="2022-08-03" version="1">MTTTEATQLLQVLSLRDEAAQQEVSSPSSSCSLASILPYLLPFCGSRQLDILGLLDHECKELCEEEWRLRVLEKFGPLRFPTAQWRKCFKLRSYLQRRVVDNVSARVYLMNAQGTTTCFSVGIGKTMMCSRERAIVYNRCERMFDLSLRINRSIQEISALIGMVSVDEARGLLNEHINLMASVASLRSSLMFESELFQVFPAPVLLDTNTLLRGTHSFDVGDDFLNATATVMMQVWASIDGMIYRPLAPPSVLANPDDTSTQDEESQQPDEPEVAPVDYQTIKLHDLSGMTIHIDDNTLRYRIRDREMCMNALVSNTYLLYLFNPLQFRPMDWTFDAVVYVGDRRYELPTQREGVFLNGNTMALRVFLSYGKIPENTSEDSATDEEVGRATPNNGNRGTRGAEESDPLEIPYNGETELFLFRLTATNRITRETKEVVHKTACFSLNQGVETAVAPVPASSVELPALEEGKSNEQHASRRSHPLAIERHVHLPWDAMICYCFNERFTLQYVECAIGFEALMHQLEVSDFLAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRB9</accession>
    <name>A0A8K1CRB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_012388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRB9"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF101">
        <property type="entry name" value="FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW67272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="41046" checksum="D2AFC9668A571385" modified="2022-08-03" version="1">MPAAPSAVVQRKRVEEEEIDDLIPDAETMAKKEEVPSFTWSEVVWYNVIILAVWHVGAVYSLLYVIPACSLAQIAVLWLAFWFMSGLGITAGAHRLWSHRSYRAKAPLRFFLMLCNSMAFQGSIFEWSRDHRAHHKGSDTTADPHNSGRGFFFAHMGWVMVRKHPNVRKEGNKISLKDLHEDGFVMFQMNYYIWTVLAMCYVFPTYVGYLMGNTWAGFWVGGIFRHVWVLHMTWCVNSVAHFFGYKPYDKNIRAVENLIVSIGAIGEGYHNYHHKYPSDYATSEWGITSGHWNPTKLFIDMCAVFGQAYDMKRSRTAAATRERLAIKEHEERLKAGVAHQASVIGRLFFGRSEEQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS16</accession>
    <name>A0A8K1CS16_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS16"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035478102" evidence="1">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="168" mass="17369" checksum="7C275AC79EEBFE7D" modified="2022-08-03" version="1">MKHTITLVAITALASATGLASAATITDSALPKLPSPMEALDTVKNIDLPKGVILSGTVEPIQAPASVKNSDDKKETDTTDNQIAIADDKQGNQEWYGGGLGWGGWGGLGWGGWGRWGGWGGFGPYRFGYSCGGLGGWAYPLGYWNAFGAGLYGGGCGLGLAWGGLYYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CS87</accession>
    <name>A0A8K1CS87_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_007469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CS87"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210:SF1">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="213"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="342"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="420"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW67797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="492" mass="54670" checksum="81987B156BAF555D" modified="2022-08-03" version="1">MGLYCRMSTPNNDRRWSLARATEFFSGDGKPDMLDIRGMTAVTKGATGKRDKFRKSVSRCGVSIYGPKHSQSAEVTGAAGTRERIFIEDPRAPCLTIDYTNEAYRLMPSSEKFSAHTGVCQILGTKCIRGGKHRIRVGDIIRFGSVGLLVTEIDTAGIGPNDATLSPSEINSLIQRVICHDEAIADVDSGLDTDDDAGDASGNDESKPRASAQRQSTSAMCYVCYDESEEGNPLISPCKCAGDTKYIHLNCLKRWNTNGEKNEICTVLDESNARTCSICKAPYPSKTRLPNGKFVSLLPDRLNPPTIMFQVVTKHSSSTLNLSTRYQLSYKMLLENDIHRPLMVGRSSQCDLVLKYRTVSTIHAEIHYAKGEFFLKDAGSSNGTLRYIYRPLSLHNNQSLHVKFGRTVLSIKPTKKIRLPHFFGGSGGNAHPHSHHSGRPDSFDEEEENFRYTPTNARNNRPQNPQTQPNTQQQPQQQSINALQSQFQNLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSE1</accession>
    <name>A0A8K1CSE1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW67865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSE1"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="288" mass="30109" checksum="C7AB269960132B34" modified="2022-08-03" version="1">MGQPTNETKVWLITGCSSGFGRQLAVAARNRGDLVIATARNVAVLGDLQNLGCEALTLDVTAHDSAIYNVVAKAHAIHGRIDILVNNAGIGAVGAVEEASSGEIQTIFDTNLFGVLRVTRAVLPYMREQRSGVIANIGSLTGFAPFPGCGIYAGAKAAVALTSQVLRLEVAPMGIEVTVVDLGPFKTQVLSKSIVHSKTIPDYDEITQGFKQAVAAGGNIPATDAALGAQALVEALTKTCRCVGRALPSRLPLGVGYDVTHSVLTSSQQELDAWKDFTDPGAFPIQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSN5</accession>
    <name>A0A8K1CSN5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_006313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSN5"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1500">
        <property type="entry name" value="JmjC domain-containing ribosomal oxygenase (ROX), dimer domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="150"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="427"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="427"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="533" mass="60024" checksum="D8E36ABD1B0B15CB" modified="2022-08-03" version="1">MSRSKQAGRRGKSKRAEAEAAPERVTKKAKKLDAAKSDEVASSSDAAREVVAKLLGETTLDQFMTDYFEKQPLLVRSEGNHKLFDKGLFSRQKLLETVGSQELEFGKDMTVVRYVDNERENYLPDNGKLGVKKSQLSGLLNKGYSCQFYQPQRYVDGLFQLNSSFEQVFGCLAGASAYLTPPASQALPPHHDDVEVFIIQTEGRKKWKLYRPITELAGEHSSDLSSDLTGDIWMEFTLEEGDMLYFPRGVIHQACTDEKQFSTHVTISVYQHNSWANFLEVALPRMVRRAFDSDVSFRRGLPVQYLSYMGTQFDPESATAKKFVAECKALVGKLSSWVDPSDLHKAADDAALDFIASRLPPATAEDGQTAGFLLESDSKIRFRDRSYVRLVLGEDEEKETVISVYHSMRNCRLHHMGMCSCILNGEEEDEDDEDDGEENDKDEEDDREEKDKDDEDDEGSDEHDEEDMGDMPIPPQAQSIVFPESLVSPLMRLYSSYPAATPISELVQAGEDETEVRGMLLRLWSEGLLETSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CST5</accession>
    <name>A0A8K1CST5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CST5"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="157"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="383" mass="42292" checksum="285A103B244EE08C" modified="2022-08-03" version="1">MRSSLASSMSTMSLGRSSIAGHGGVLRNDSVLYITVLGARELKDTQKIGVQDPFCAVYLMSGGQEGSSPAFKTSTHDNGGVNPVWNEKSTIIIPDVASDVLKVKIMNENWVGSNTIGEVAIPMRDLSRGRSMEKEFALTPKGFVRVLLYLALAHENPTTQPRVQMGEYPQHFIPGKSKLFLSLVTGDKLRDIQAFGTQDPYCQVYVTKNRRYPPAEDMVYKTKTHDNGGKNPRWMEAMTAGLRCIEHDFLIIRVMNDNHLKDELIGEVCFKLELLIGRGFEDKMLPLEAENTIVGQIRVQLALFNDEVMEEDDEDIHAYASDLDGCTCSIKSVQRATKVGDVIINGIAPDGVHYLEAGSVVATGCTIAGDYVMDKDCWDGDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSU4</accession>
    <name>A0A8K1CSU4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Globin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the globin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSU4"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase NAD(P)H activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071500">
        <property type="term" value="P:cellular response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046210">
        <property type="term" value="P:nitric oxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01040">
        <property type="entry name" value="Mb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044399">
        <property type="entry name" value="Mb-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF6">
        <property type="entry name" value="ABL201WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Globin" evidence="3">
        <location>
            <begin position="134"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW68599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="241" mass="26997" checksum="AA651869394FAFFB" modified="2022-08-03" version="1">MGTCASSAVVGVFPHVGRSKQLTREQILMIDTHLPDFRYYEVSTEEHRQVAASHWNAVFKEVPSSRSTRTESTGGSKSSSATQSGSRIGILYDTFYAYLDKHLPEIKPVFRSSMHVRGKVLVHISAGMRSILASDNLIDKITALTRTHVRFGVQMEHFNAVGNALLYAMRETSEGSWSPVIEEAWRRLFAHCSALLLAHQKKANEERRQTKDMENIFTAYAQGPLANDLYSSPSNLPIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT50</accession>
    <name>A0A8K1CT50_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT50"/>
    <dbReference type="OrthoDB" id="123399at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="496" mass="57015" checksum="693097D00AF478E7" modified="2022-08-03" version="1">MTSRCYNPEGFDAHPPADVLLRRLYVDVDAYRMDLHHQRFARMSRQERLSKYNSIIIPIHVPLARGETVDEYEKRFARWLYEAERLSIDDVQHKPQMERYMRIRFANWVANQTYTPHTSHSPSRSREARRSEDKRTAISPEKKRQRTYEDDKKKPWRETPPARKDEAKPAERRSETSSQDTASDLVFPSRCTVQLPSSTASLDAFTTAYVACGCRRCFSQCVTRMGTHITQLEMPKLDVSCVSPSHSRNSSSPRHSPTEGKRGRFLDLTSDGNHVLKRLRRLEPHEITRKSSSSDMASSESYDHIEKQLLGEYDQLNDRVLANERVLELSIKRQQDTPVDDIKQTSAQLDAIQELQTLIQRERDNRSAALAMVIVYLWRKELEQLEEHLKSPNATNVPQVASASHQQCADIAAELIIKQDAAAASKKKLGERLKHRSSGSKEAFAHDAKELGEQLVSVQREISALITARREEFVVLIQFDEHVRNLIRTILSSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU30</accession>
    <name>A0A8K1CU30_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU30"/>
    <dbReference type="OrthoDB" id="10250191at2759"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000850">
        <property type="entry name" value="Phospholipase_D_PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="480" mass="54221" checksum="1A770C9ECBA6B453" modified="2022-08-03" version="1">MASHEHALPGAGAVGYEQIFRSLARHSRVFPLHSQDVQIIPSPTAFYEQLLSNIRAAQHRITISSLYLGTGELERGLVDAIAAKLQENPAIHVKIVLDHSRGQRGGQTKSSVSMFKELMKAFPENFELYLYKVPQLRGLKASLPPPFNETIGVSHAKVYLVDDTLILSGANLSEDYFTNRQDRYVQMRDCGGLAAFYHQFVSTVATYSFQARLEDHATMQYVLVAPPKRTGSKRVAMKREFDELVTRHKHTEEDIDQEVVFESAHDTWAFPTLQFTPVDVTHDEQVLTDLLKQLPAQSSLSIASGYLNFPPFLDDLLVKCEANLDVLTAAPIANGFFNADGIKGALPMAYSLIEQEFYEKTRSRAYATNIREFNRSGWTFHGKGMWFSPSLDAPPQLTIIGSSNFGRRSYGCDLESQLVLYTKSPTLQGNLRDEYDQLKQNAELVAEQVWKRPDRTLNTVFCWKYGHWIRPVSKMIAAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU52</accession>
    <name>A0A8K1CU52_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_001750</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU52"/>
    <dbReference type="OrthoDB" id="1911066at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035464828" description="subtilisin" evidence="10">
        <location>
            <begin position="23"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="183"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW69594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="494" mass="51486" checksum="90D7C639CAA2F9B2" modified="2022-08-03" version="1">MVATKFSLVVALAAVATATASASVPRVDTGVHRTLRQEGTVNLIVTMKQSTQEALASVQEAEYSSRGARIEALVSRLEKHATLSQKDINQLVSQEATTASGNPLFASSTSYWISNQVSFKGTTPALLDKLMALPSIAEIREERVLQLDPLIMSASNSTTGNVQPEWGINMIKAPEVWATGNKGEGIVVGGIDTGVHGTHEALKGNFRGEYGWFDPQKKGKTPYDESGHGTHTMGTIAGANGIGVAPGVTWMACKGCDDICSESDLLACAQFMTCPTDVDGNNRNCSKAPVIVNNSWGGRQGDPFYEAAVDAWHAAGIIPIFSVGNTGPDCGTVSSPGDYDSVIGVGATTITDSLGDFSSKGPGVLGTSKPDLSAPGQDIRSAWSSGDDAYETTSGTSMAAPHVTGIVALLMKAKLGLTYSQVKEILLASVDNEKLKPSGLTCGDKPDGVFPNNGYGQGRSNAMKMLNMTMEVTPAPSTKAPAPTSSSPIPASSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CU58</accession>
    <name>A0A8K1CU58_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CU58"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="76" mass="8917" checksum="2FA1B8C52C6EF00D" modified="2022-08-03" version="1">MAKSKMTKRKTTRGYPRKPKMRQKLVDKMMSEGGMRDDFQHDMHIIEINGIDTGVWAVYKQWVCSLPKIDLFITAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUE3</accession>
    <name>A0A8K1CUE3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_006299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUE3"/>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.30:FF:000001">
        <property type="entry name" value="tRNA methyltransferase 10 homolog A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW68831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="30249" checksum="3C99412448268A89" modified="2022-08-03" version="1">MEATEAKDGTLSRRAERRAKRREHWDNKKEKKKQQRRLEKEEKRQNQPVVELDMSEEAVLRRRERAIAKRESYLMASEEGLQIVIDCGFEEAMSEKEKKSLSQQIMFSYGVNRRSAAPLRATITSLRGDTKDNLTKISGFNEWLAFKSTELSYMELFRKEALVYLTADSPNTITELDKDKVYIIGGIVDRNRLKGATYNKALEQGIATAKLPLDQHVDMGASTRVLTVNHVFEILVRYSETKDWKGAAMSTLPSRKGVEEKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUI5</accession>
    <name>A0A8K1CUI5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_001047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUI5"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="396"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="538"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="584"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW68891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="650" mass="74417" checksum="5FC266B01026880A" modified="2022-08-03" version="1">MRERRHLSGNSNRVRPVSAVPTCTDHSAASEHVTSQRSPQERTRRGCATARGTPSETSMAQRASKRRIQSARGPRTASAGPLGPPEALPRLPQLAPFVVSTASSSQPVQWAVRTTTQTPLTPTTDVPPHVVVMLADFRALLRERYEGKRSMRRAFLNCDHDKDGELSAPEVREMVHSLGLAPKLGQENVEDLVHHLTSNPSNRLQYDAFCTFIYGDQNDSKPPKEAAASTNASVKPTTRVLNTESIDATVDASDRALYPDVEHVLRLLRTKYQQRKFREVFRHWDADKDGGVNRQELDQNLRRLGVKLPSAQLQELFGTFDRDHDGRLRYHEFIDMISGPVAIEHHNPALQARLRDLAQREPTDAYQILRNGAIKNPIERIDEEAICAAVQEKLTVFAPRIHDAYSAFDHDHSGNLSYHEFRQGLNELGLHFTEREFLHLVALADTDGDGEISFREFSTMFHRPRRRAEGKSNEKDPTASHVEDEESRKEAMELSSTQRERFSRGTFDFSHLTRRVKIPTRHGRTPQHDTMNMLREESLTSDHSRFSTETQIYGSGQPLKTRGGAYRQDARDVDTRTTIGQSEKQLRDASYTKRLERIRQQQQTYEERTAPMQHTHDEQQQRRVESLQRHQQRYQQSIDEQERHTKHPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUJ3</accession>
    <name>A0A8K1CUJ3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUJ3"/>
    <dbReference type="OrthoDB" id="126305at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="352" mass="40930" checksum="6419B6A7B4F942F3" modified="2022-08-03" version="1">MPNEAAKLMEVNAKNMIALHFRRRLHQYIRFRYAPEGKLEMKHKDAKRLVDSCFRVKTEPVLDEDGQPAGRTTPVWTEWDDTSDPVEKELRKWLGIVPWHFSIRANSGHFVRKLSDMLSWMEKFVEKHPSQKGARVYSLLPVATSFQAAYVKINGSTLHGIFARLLKKHPNVEEYLRDELNIVPTNKITSESQWPFTRTIFQMHRSEILRQMFDVAQFETKNRKFADELKTNGYAVSVTMTRPLTTTSVTVVNTKEHPSKKELKEIKEMDKFRMNSPKLKSHKIVLKCTRNVLRYTNSGCKANFWNRDVNASLNMLELLRSGLNGKHGTSRVRAFHAWSTIVEEKKIGWKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUP3</accession>
    <name>A0A8K1CUP3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUP3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="276" mass="30204" checksum="F410B94DA2734DF8" modified="2022-08-03" version="1">MTYSLYCNYAHLLFTALVVSTMSLIIAHELLQLRANDVLVVPTSVLVALHLRTLFSLEACVTPLASVFFKRQLDSYRVNQVFVLVLALAALVGQGIINWNSLLLTSSFDDKFCEARLRGECTGDDSPPIAGSLRRPDAPGLVLSPRSDAIASIQAMSKTQLECMELLLLLNPEMPQLGAWEGIVKSVNPTNETDAWCKRHVRNASDASFAADNAPSTAFGPEIKSIYQLAKWMSIALLCVMVMRGVMLYNAVTASTESPVAIVVSQPEERKMELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUQ2</accession>
    <name>A0A8K1CUQ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001176</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
            <location evidence="2 10">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUQ2"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21450">
        <property type="entry name" value="DLC-like_DYNLL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000005">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="91" mass="10735" checksum="52F488AE1C755632" modified="2022-08-03" version="1">MTRENGKQMETDMDEHGDMKNDAITQANIALEQFTQEKEIAKHIKTWMEEKYGPTWHCIVGSEYKCAFTYESKNFVRFNVGKKCITLFRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CX14</accession>
    <name>A0A8K1CX14_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CX14"/>
    <dbReference type="OrthoDB" id="103893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56207" checksum="1674E7EE2BD82D8B" modified="2022-08-03" version="1">MKFPLPRNPFPPLDLSPEYLHQIQLLTQALLDQTVAEYEQHVHVNNRVVDKTKWKHIKTRENLHVYRAVGDHSDDHHMMVAEQLMDASSSNAMPTSRMNVKGGNRLMGVGTVVGNLPDLLYCCVSRTEDEMQIRTSYVPDECVDWRVLYTLPRGATEDNPFQNHTIKYHVKAAPGASSMFVRPRDFILLDCVGEMNLASGERVAYCIYHSVDVPGCGAVDGLVRGQFSCTYILRSLPGNSVEVYMRCISELGGNINDTIAAISIANAVISIWKMPWGGQNKKLAWMLKQRKKGAKQGAKTEKTDRCPLCTKSFSIVRSSATCELCRDQVCSSCITTRKISYVRPARELMQIPTDFCKSCITQCSLLDANEVARQEFIPANRTVSSSISSSTVGRESGQSNRPYTHSSTESEGWGVTPVSRVDLDSVRIETVNEWEKTPANPHGSVYSSQSSMDGSALSHPSPSVGDPHKMQLLIQMNQLRLAAEQTYQITKDNERAIQSSVHSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBF1</accession>
    <name>A0A8K1FBF1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008704</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBF1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF547">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="79"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW56056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="464" mass="52581" checksum="CB14212247A9CF2E" modified="2022-08-03" version="1">MNDIVMEDVTQPPVSEKERKARIINGVQELTQVYRANGGQNYFKPHEVHLNDDLRFTVQEPRDYFSTKVAEEEETKSDESDSQRLVAGFFDPVQHTPSNQVVRPTKTGIVKFAYHFATKAGKSPGEIKTSIHPTAFKVMDRERLQHCGEDTQRERRVMMALRREGFRKPRQNPLVEPAYADVRKHTYDYFPQWRFYEDESNQYMMTDFASNGSLVQYTKKRIDSYNVEIAHLMSTYVILSGFPVTTAVTKLWRQEALCIFSGIVEAVAYMHAKGVCHLDLDVYNIVIDAMKHPIIVDFGSSEVAAVDGSVGRGRPILCKHNFGAPEVVAHNRNVERSPGVDGRAADMYSLGAILYWLLFIYPGESPIVDPMKNDPRWLQHLIHHLAPGSGVHEGGNCAICRSLVPLETDVVQLFQALLTNLAQRITITSLLDIIRGRDYQVHGDTITRSQAVFEELRKSMHGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FCJ2</accession>
    <name>A0A8K1FCJ2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NudC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_003181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FCJ2"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037895">
        <property type="entry name" value="NUDCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664">
        <property type="entry name" value="CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664:SF1">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="58526" checksum="54C4F29D4DA09AFE" modified="2022-08-03" version="1">MEIKRDLVDKDFDRYVLAVDGVHRQETLLQSAVLEPLDATKTTRKAQWEARVHYNALTADPFRSDAERTVAYYVDAEYQIVQVVAHASNVIETQPIYQMEKQTARRENVTLRAVGKGLLACNDGTGKLRFLKSEDADKADGSWSAAYECEPLGSSPSLLLEGVYDEDTSAFRVALAEPIQGTEKEAAFRLWVAEVSCATGSDSMDVDSGAVGVTHNAFEVGVVASMPEFLTFQGAELLVLIEGTCDLMIEPTAEAQVSAVVASNASQPHTPKRHHDESELEMDIDEVLSKLPRAGIGYHGDISDVKHLHDLAVDLTTPLEQRFHKSSTPYSSLEEPLHSASTENAAAAREARFEMPTPDTILGGFEECDDIDPNAKAALFLVDTKNKLVQDKMDIKCSNFRFLCSSVGNSPSAALLFQNDVHGLVFSIQVQASRFVLSHTSTLPAFGFVQASKQDKKYMTFHTDADFACIAEFERRIFVYHGASTDAEHQAHTRKQNVIEVGDHQLLGMRVVGKSVLLLSPHHIYHIRISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDA0</accession>
    <name>A0A8K1FDA0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDA0"/>
    <dbReference type="OrthoDB" id="164491at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="295" mass="32837" checksum="15E60614B6BBF8CD" modified="2022-08-03" version="1">MSIWIAPFEWRALRGRSEGQGKRARGWGRRGHLARVVAAYAPEKTPEEVELVLNDYAGREEQLIKWYVAKYALDGMEDVEWMLNAVFRFKHMKPSDDQTPEFCKRLAQVMVKFMGKCGGAGSESRGVSASRDGPSPHFDPLEDDTLLPVDEFSTMDGVCLKQAMAQLGRITKPQRGDIWCEAWFPQFAGMLQMVCTSVKTVRLRIIALDGWERVLHFLPDGSSVSSAVAKTHKVLNCGDLDLELRADFQQALANELNSAKQRKESSRSGTWRDTGTSEDADVPSSSGAKCSCGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FDR9</accession>
    <name>A0A8K1FDR9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FDR9"/>
    <dbReference type="OrthoDB" id="266663at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000006">
        <property type="entry name" value="Dual specificity protein phosphatase CDC14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="183"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="266"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="405" mass="45784" checksum="4FC434D13DE933CE" modified="2022-08-03" version="1">MFTLASPSFLGKPKPAPPIVEFLRDLVYFTTYSTEPRARDGVVFFSIDEKLAYNSFYLDFGPHSLGSTFQFCSVMNKMVTAAAKTRRKIFFYSAPDPQLRTNAVCLLACWGLLFHGMSAERAYAPFTRLSFPAFHDASPAVCEYKLTILDCLQGLERALKCGFVDPKTFNIHEYHHYEQVENGDLTWISPKFIAFAGPQQSYNVSSEGYVMLTPEHYMPYFVKNNVTLVVRLNEKEYDETQFTRKGITHLDLYYPDGATPPPCMLQRFLQICESTPGAVAVHCKAGLGRTGTCIAAYLMKHFHFTAKQVIGWLRLCRPGSVIGPQQEYLESIQSWMWELGDRKSREILSDVKKQGSGSSRVSGLLTTRAISVFGVKKPLEIMERQNTQGDHLMRLKRTFQAGTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEL8</accession>
    <name>A0A8K1FEL8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW58079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEL8"/>
    <dbReference type="OrthoDB" id="7869097at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23945">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509:SF1">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="5">
        <location>
            <begin position="56"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="289"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="41020" checksum="A7E36831FEFD158F" modified="2022-08-03" version="1">MTATTCDSASSSSVYDPSLYDSLESYVEQMNAQLEGKSAVEIVEWAVATFGVDHTALSTSFGIQSAVMLNLVSSIDNRVPVVWIDTGYLPRETYQFATRLTKEMSLNMKVYQSPISPARMEALYGKLWEIPTVEAHKQYGYIRKVEPMQRALRELNTKALLVGVRAEQTANREGMKVVNVYEGRVKICPIIKWTKKDVEEYMAANNLSYHPLKAQGYETVGDAHSSRPVSAEDGNERSSRFHGVAQECGLHIDMKDVKLEDFAITLDDPAALTEREQDILAKTKQSKGIVIITKPNCKYCRATKELFQERGWDYEDFTVGEDVSTQSVQVIVGQPVKTVPQIFLDGKYIGGYTELCVHLDIPSRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF55</accession>
    <name>A0A8K1FF55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF55"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="330"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="591" mass="66551" checksum="777025016E400A71" modified="2022-08-03" version="1">MGMVWAPVASAIMMASSLASFMTMLHLRFRWDVHVSCVRWLFWLFFLYVWLWSSLRAAYFFWLGMQTQAGIKPRDDGDSWAYKQVDHMGIHAMLYLRQASKQWLLFLYVFGDVALLGLAATLFPLTYELCRIARMSMDRGPQKECLQIRRYALGIHFVLLAFWITESVLVIVQGDYTQDTLRCLMSIYVVQFIGLVFMIGSVLHLKINGRKYETIHGTFIASPVYQRLKRIMIVYVVFAFQFQLSSFILFVLDPKDKRGAVEYIGVSQLIYCASGLALSITTSCSQSCVLTACSFCLPDDFEATLMHQRLGNVEEAPSEDDLEAPSTDPVFVFTDIESSSALWAIDDGQMMDQATEIHDNILRSTLPKYRGYEITTCGDAFQLAFHTIRDAVEYCMDVQLQLLVAKWPKDIHGAVPATNRRRSSHRLVFNGLRVRMGIHDACEVEGALVQDIHAVTGKAIYTGASEVTAQFVGDLGSGGQILVTSRVASWLKYRLDDLSVDFALERVGLYTVPQVNMSVEVFQVLPSILAGRMRLFPTPDKGRARLQHPLRPSRRGTSASQQSSNGSTQSREITAQYVSIESLGLRNAAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGE3</accession>
    <name>A0A8K1FGE3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_014306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000114">
        <property type="protein sequence ID" value="TMW57703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGE3"/>
    <dbReference type="OrthoDB" id="71701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="166"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW57703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="252" mass="27929" checksum="42B2E647FB603093" modified="2022-08-03" version="1">MNDEEERHASMLDVESALYGAIATINMKHIPVGIHPPTGVLAGPVIAAQHALELGLGMPSMPTTPSVEATATTPKATRGRPRMHGPGRKKNQSLRKPVTYAHKLAVINFYEAHDKDINATVREFYANLTPSNIGSRKRQIYKWVKERETIEEMCFKQTTAGQSRRREKGTATTLSNEAEQELVDWIVALRQSGMTISSPMIKTKAIEIADKYGVPKGSFQATWSWQQGFFKRHHIAMASVPSTTNDSDGMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGN8</accession>
    <name>A0A8K1FGN8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer kinetochore protein DAD4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGN8"/>
    <dbReference type="OrthoDB" id="5516652at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41433" checksum="E5D57B6AD420533C" modified="2022-08-03" version="1">MLCSKHKHLLQPIFTMQSKAQEKCLGKAFWTKQRQKRPKLLAGRDSVPDLAKPQTIASHVATSNDTPKAPALPPKQAWTEIQVSTSKPTATEKLAAKQKQHEQEVLEAWITTQTQVQPLVQLYFEAYAEKHTVDTNLRTYLASGKGKSQSPEDVQTLTDLRYQAAVCDKKYNVAKAKLHEVWDAEEQAETEKRHHAVRGVVHGVSSKTLHKQTGKQSAQSVIGSYMDKKLDAATQEIHQVFQQRWETLDKAAQYVTTTTTARDKPSLRPSVPNGTNRVVPVLQETETWTEHFDTHPHEEKQKALLQRIAGSVTRLNDVLKEINFQIEKSEPLREDLALTCQVWKGYESRVQLHCNAVASTTNGHGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGY4</accession>
    <name>A0A8K1FGY4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_007337</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGY4"/>
    <dbReference type="OrthoDB" id="123467at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF14">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="133"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="40751" checksum="A048F91D08E16D46" modified="2022-08-03" version="1">MAELLQHLRALGARGQPGVFACSGEAETPRPIAISYKTPTKNKDTNDSPTRRYKTITFPPSNNQNIQDLLSVCHPETHGHGNKTVLDASYRLTSTLDASEFTLSFDMSELSILPTIQQFLTPQGEFSEKVGVRASLYKLNVYGPGGFFKSHVDTPRGGDTFGTLVVCLPCEFTGGVLTVRHNNEDERLDWGASGFASANMLRWGAFFSDCEHWIDEVTSGYRITVTYNLHPSFAPDGAILGVSLARYYAIDGSEDIVMLKGVDQVWKEALDYLGLQYKYVLAFKRNEESFERGSSRTQEDEDEAEWDDRESLDDWDGDGDFSLFLRDKLYMINSARVDLENGAFVFERTEKRFFLRSSTRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGZ7</accession>
    <name>A0A8K1FGZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polymer-forming cytoskeletal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGZ7"/>
    <dbReference type="OrthoDB" id="192707at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="HYPOTHETICAL CYTOSOLIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024:SF4">
        <property type="entry name" value="POLYMER-FORMING CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24382" checksum="646558FCC834FB39" modified="2022-08-03" version="1">MDDVPVSRNPPPKPKRTAVPPASISEDDNYSDTGYESSPARRGRNTRVERQPQQQQYSPPTTPTYPPGRSHKVPIVDAEPETTIGVAVKMKGELSFDRLLRIEGEFEGKLLSKGSLVIGTKGVLTGNVENMKEVYVTGGRIVGNISVDKLILRDKAQVFGNITAKTVKIENDCIVIGKLNVNPQAPERINNKGEIVKEEAAPAAAPGSATAGTPAAAPGSAGAAAPPKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH39</accession>
    <name>A0A8K1FH39_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7326421at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056432">
        <property type="entry name" value="Beta-prop_GEMI5_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23770">
        <property type="entry name" value="Beta-prop_RIG_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Gem-associated protein 5 first beta-propeller" evidence="3">
        <location>
            <begin position="135"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="2">
        <location>
            <begin position="424"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="637"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="693"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="736"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="4">
        <location>
            <begin position="857"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1345" mass="149417" checksum="C3292119F5BDE7EE" modified="2022-08-03" version="1">MTKMAEDDAFRGVNDAEAVISRESQASHAIDQVKKQLRVLPPSTNWYCAQICDWGYDSTQHWLVAFGAKHCIYLYEMDLSASDGKTSKPTIDQVLERAPRLSFRAQIKRGKKDARVTAVRFMLDAHDKLRLVCGGEEGAVQIWDVSKMQMVDQHRKHGVEVMAVAVRFELDRNLVVAGDRQGRLSIWHRDTNKVQLFTPVKGDGVFSMEIAPHDASLVAVGYRSGALCVVDLTQECVRYRLDGHDQEVQAIAWRPSSLDANGVPMLASSARDRLIKVWKFPGDDAPSLSRQFEIPKPKQASSYTQSKRLWLPVAWSHNDTSDTNRLWSGSFEGNLLLWQWSDSTSGKSVKPTIARNGHSRLIFSIVPAAKVWLDSSESAQPALFLTVSLDRELRVWREEPPSASRPLACLESVIGLGGHVYDLAYNERQHVLAAAIGDQTIRLWQLTGKQSGYQVDLLWKGFQSKITSVRWHPMQDNLLAYGTEDGRLGLYDVQSKTNTRLKTSHSGEVDHIEWTMLAPKAEASENTGSSFIEAMQALERAQEGGESLEVALQKQETTSTRNRSTETSFYLWSKDKNGQLYRTDPEKTGHSEIRTDCASFTWTSAGDFVAVGSRSGSIEVSTPPSEPKAPLALRKRLHEHSEEVTCLAWDTSDAFLASGSKDGKIFVFSGLSGQESSRYRVLLGYGEHVISALIGHKNAITKIQWSPSSNGTLASSSADGSVRVWTLEDQACCATFNQHIGRALSVSWIGSAILASGSEDQTIRIWNHTVHPPVQASNREHAKAKPTVKVEKVLPQGVSEKAGANSAIKPVGASSTTTPKSAKKVTDSFFHKDSILLSTSNMVHLSENNSASKGFEHSAREYLKREKEGFREEQNWEKLAHLHLLEGRIAEALRIVAKERLLTAQWVAYAPMASIEVWREVANLYALQLQESGDFKKAATQYLSLGKVQMAIQCFVSAKMYREAIVLIETRLGGDHSQLEQVKTGYAESLLKKKRTREAAQVLVSVGSDEALLRALHTVAVSEELNDVAYALELWAELQSGEVSTRLVLPTRDFLAMVATSLRSVNFELTTKALDALLATKQRSLEGEQGTMKLYRVSRIIIKCAEVIWSHDLHKASQYDRSPEGVFESHPSDNVSSLLAHFHRESTQPWASELESLSQIPTSALRSRAARVINQVLSECKENGVWFTGGTLSLDDVQDLLMDATSFDFLLGVDAVERSRAKTIQPLLSASCQVLKFFVELMNGYLLSALEELRSLFEALSSVSVNSSRDLSLVDVITLFFPGGLIDPLDPPLYGELADEVDETRSLWEYFRSCQESVVANYTREEVDEAVTVQGNEIKFSDPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH85</accession>
    <name>A0A8K1FH85_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH85"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20251">
        <property type="entry name" value="Complex1_LYR_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="6"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="101" mass="11305" checksum="D0312231D4935B00" modified="2022-08-03" version="1">MTHEQNVVRLYRRILKLAQQYPSVKRDAIIQDIKLEFHENKALTDPRMIEDKVQSARQGIRELGMYANLKPAAGAWTVDVGRDAAQGPPSTSSTKVVGDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH94</accession>
    <name>A0A8K1FH94_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH94"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="92"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="306" mass="32987" checksum="FCA5D196420F91E9" modified="2022-08-03" version="1">MTSEVERLLHAQEDAIQTPRRLARRWSLSPTTTKRVKITAYVALAVIVVVAVTVLFPIKQILVATTTWVEEHHLSGACIIPLIFCIAVPLAIPVTVLEILGGSAFGVFFGVMLNLFGKTCGALTAFLLGKRLGKERLGGYLQANFPVFTALAAVIESANWKPLVLIQLSSLPPVVKFYGLAVMDVSVLRFIVSAIIGGIPGAILWAYVGFHTKDLLVSDGSAAASDHTKASSYAMVVFGLICTVVAMVSLFFYTRRELQAQLDLASKKSAVDPDYDDESTVLVSQASSCDAHYGTKHRSSMDALLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHC4</accession>
    <name>A0A8K1FHC4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHC4"/>
    <dbReference type="OrthoDB" id="2155027at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="177" mass="20566" checksum="AEB0428FC73056AA" modified="2022-08-03" version="1">MSQFTLRIASPAEAETLSAISSKTFFETFEDVYSAEDMQTFLSTACSVDKLRQEMEDPRMYTVFVYTKDDQVNPCGYGMVHDCTVRTGDDGVPEDYVQLKRLYLLKAVHGKGAARIVMDHMMEYMHAKQRKVIWLGVWEHNLRAQKFYEKYNFEETGEHVFMVGATKDRDLLFTLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHL7</accession>
    <name>A0A8K1FHL7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHL7"/>
    <dbReference type="OrthoDB" id="154322at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035445588" evidence="1">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="248" mass="28062" checksum="925FFB412AF20F0F" modified="2022-08-03" version="1">MRNVMVASVALAMFSSPSSVSASLWTSSFSSSSHSPLPLWPSNSTTSRGVCFYEKPFFKGERVCLGAREPECASVLRINAPPTIGSIRFLRRRDEEEDDNETPLVVNVRVTVPPYDQRVESFSYSVNDTQYDSVVQELYVERTGRVCWLADTMLRDDGACFNKSVASVDERYQDAFYETLLFKQNASDFDVVAYEHEDFNNDHPYAMSKRFTASSRDLGLGGTEAKTLVHHVRSFRFVQTETNTYDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHM2</accession>
    <name>A0A8K1FHM2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHM2"/>
    <dbReference type="OrthoDB" id="433124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23158">
        <property type="entry name" value="Prefoldin_UXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13345">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13345:SF9">
        <property type="entry name" value="PROTEIN UXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17199" checksum="AE2974B1C56470B2" modified="2022-08-03" version="1">MATSVEAQETQAAVQKYGTFVEEVLKPQLQASLAQRDALTTEIREYQELLEFLTAQIERQQTEPTAKLQLLMDLGQRFQVRAKINDPTRIIVDIGLNFHVEMTLDEAQTFVQSHLTHLSDKRRTWQDKARQISDHVNLVLDAIQQLAALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHN1</accession>
    <name>A0A8K1FHN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHN1"/>
    <dbReference type="OrthoDB" id="118048at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="169" mass="18947" checksum="6F9BC44E7D9EF276" modified="2022-08-03" version="1">MYARRLRGVFSFRQAIPVLDEYLSSIRIDDDDPGFLFNWLPINVGAFVTAANGLDPAQAPLWLRTPLTTESFINDVIDRLRPVAGGHVEWVLLAPNTPEQFAAIHVRLAMLQAHDFMQDVAQAAFPIVNIGAQYLATTYLLTDTRAQQARPNRLEAITPSGQPLRQLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHQ8</accession>
    <name>A0A8K1FHQ8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHQ8"/>
    <dbReference type="OrthoDB" id="122199at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="386" mass="45187" checksum="939BF95D9CCC4F1D" modified="2022-08-03" version="1">MRSLVSIQPRPKALKVEVSSVSEAASSAADTRRQRHRVVVKRAYHQRLNRLRDLRREESVLQTQFHTALVHIATLLRDKPTQNASSTTIRALLASYVGLLTLKCQLEEEQLELSATMERYTLFHSRVQQLVTENTSPIQYVTLPTPIDRALVTSTNKSVNPLAVTIDSVSLSTCYEVSRRTWSDIQTFMARTDHFHLGSQVFGWEHRYRFADRSERHLQYSISKTFPSISAQELSRRSWRAMTTETSYQALHTSSMTSRLRLIQRVDEHNLIFLRLLGRPNQETVFKTRCLISRFQVERGYVTIYRSMNPEYVQPAVKEDSPHTVWLEMFSWTYFEELKEENKVRFEFGGEMRHQSTDNARFWMMELLLMALRWENMVVGPRFTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI73</accession>
    <name>A0A8K1FI73_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_002452</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI73"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="38"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW63511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="215" mass="23821" checksum="F8F5BA75992A9565" modified="2022-08-03" version="1">MSRPFPPRKPSDYSKINNEADDSPGEDDYVRNQRSLQQAERQKQDESLDQLHVAVKRIGDMSLTISSELETQNSMLDDLNEDTDKANDALQAVTKKTQELIKQSGGMKNFIVIIVLSSVVRKLIPFGNRVLVKRFEPVAKTASGIYLPDADQQKQNEGEVVAVGQGLRNAKGELVPVQAAVGDKVLLPEYGGSLIKLAGEDFHLYRDDDLLGKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI82</accession>
    <name>A0A8K1FI82_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_011590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI82"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="62"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="454" mass="49852" checksum="6AFB1523254EBF05" modified="2022-08-03" version="1">MKIEEVQSTTKTQRIATHTHVKGIGLDADGVALPIGSGLVGQEKAREAAGIVVELIKSKKMAGRALLLAGAPGTGKTALALGISQELGPKVPFCPMVGSEVYSSEVKKTEILMENFRRAIGLRIKENKEVYEGEVTEMTPEETENPLGGYGKTISHVIVGLKTTKGSKQLRLDPSIYESLQKEKVSVGDVIYIEANNGSVKRVGRSDAYATEYDLEAEEYVPVPKGDVHKKKELIQDVTLHDLDVANARPQGGQDIMSMMGQMMKPKKTEITEKLRTEINKVVNRYIDQGVAELVPGVLFVDEVHMLDIECFTYLNRALESTLAPIVIFATNRGVCRIRGTEISAPHGVPLDLLDRMLIIRTMPYSVEEMVQIVKIRAEAESIKLDEEATQRLGEIGAQTSLRYSVQLLTPSRILAETQGRTDVSVDDVEEINELFSDAKRSAQALAQSDGYLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIE5</accession>
    <name>A0A8K1FIE5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_009487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIE5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="229" mass="24947" checksum="C834EC3226497D14" modified="2022-08-03" version="1">MSHPKMNHVALERVRQAESHTVNRRVTNTLRAICCPCVSAAQVASSLGYSFYVVLLEFSVLYLTGLAFSAAALSVANESGFNLGFIISGLLNKTALYCIGPLTSALVIPVAWSVDAFEADENALDNTRVINKWTFILLGFNAACDFVFMLISFFMRRKFRQRIGVEQADCSESCGEQCCVWISLSAATASAEQFGEASPSCFGFGPLDVIPAYEDYEQSVPQAVIVSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIY2</accession>
    <name>A0A8K1FIY2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_008132</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIY2"/>
    <dbReference type="OrthoDB" id="156390at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035454267" description="Apple domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="146"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="419" mass="44902" checksum="8C8B5703CB79CA86" modified="2022-08-03" version="1">MLKQSLALLAIFYGVLVSTASAACQDTIGGTCGNGTLPREQNCCSKGYCQPWNSGYYQCLDTPARCPTQETDIDYYGEDIKTIKGLLPNQCCDECYNTAGCTAYTFVNENSDGKSACYLKKATSGRVEKKGAVSAKLAEPQAPGNCPTLDRGFDYVGSDLQIVRSVSLSQCCDHCGNTTGCTAYTFKTMDWDGQSSCYLKYSDGGRTAANGVVSGKLKDTPAPTNCPKQEKDIDYYGNDIKTIKSIPVGQCCDACSVTPGCVGYTFVEKNSDGQTACYLKSGVGGRRPTTGAVSGELKCPTQPFGQCGSSQTGALCCPQGQYCQPWNPSYYQCIAVPEEKKCPTVVTGIDFYGSDLEVKYGLQPGECCDACYNSTTCHVYTFINYREGSTACYLKSAITEQRANTAAISGYKNKLAIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL0</accession>
    <name>A0A8K1FJL0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJL0"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056524">
        <property type="entry name" value="KIF6/9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF67">
        <property type="entry name" value="KINESIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23735">
        <property type="entry name" value="KIF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="31"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="738"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="546"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="118"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW61922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="828" mass="92547" checksum="6CC78D475DED91A9" modified="2022-08-03" version="1">MDAKSEYEEEEDEVPQQAPQPEQGDSEGDSNIRIFLRVKPSKRPSGFFAWDEDTSLMEYNIPKDVAAGLINNSRTSYKFRFNTVIGMEAKQAEVFDRVGRPCVESALNGFNATVFAYGQTGSGKTFTITGGAERYDDRGLIPRALSMIFEEMKKNPNRQILVHVSYLEIYNNQGYDLLDPNHESTKSLEDLPKVSMLEDEDGNCHLRNLSMHLVHAEEDALNLLFLGDTNRAVSETPMNLASSRSHCIFTVSLECRRTGSEVVLRSKLHLVDLAGSERAHKTGAKGQLLREATYINTSLHYLEMVIVALHEKNTKGRTHIPYRNSMLTSMLRDSLGGNCKTVMIATVSPEKEQTDESVSTCRFAQRVARVRNDARLNEEVDPQIIIRQLKAQVASLQEELAIARGDVKEGDELKDYELDKLRLRVQDFVNDPELTAHLNMGEFTYTKMKACFDILRTMAKGGGGVASSSASSVRKPVGGGNQDLEQRILELEQLVQQRDNEIAIMVNMIRKEKNGRVGGSMELPESLLQRQMKPIDNNQVEALATKSIGGKSSSATASKPPPPPENTFMATFQVDPAILDDPAKAFDAFKTQYPKNDAIRENKLLLKQKYDAAKDLANVVNEARHKIKHLTVQMEKLRKQQAITEEGLLSQDSPDVKAGSNATLTDTTAENKLKDEIEEHKLVYKKGFHELSELKKEIQHIQKLLEMGRIKLQKDFDLWYQRQGKGTVLTETLLASAQPKVESPVVRRSVETISKTSNQEKPSAKSASPSRPEKRPTTPPSRRPQSPAGDTKKPATPRGSNATTSSVDDDVSGFYEALDILKRRSVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJT5</accession>
    <name>A0A8K1FJT5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJT5"/>
    <dbReference type="OrthoDB" id="21573at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938:SF0">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="Translation initiation factor IF3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 3 N-terminal" evidence="5">
        <location>
            <begin position="65"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 3 C-terminal" evidence="4">
        <location>
            <begin position="139"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25240" checksum="C08D77DACE24B1C6" modified="2022-08-03" version="1">MAAVVQRVSWRCAVLATARRGVLSAPRRELHARTGSSSVAFRVSPVIQSLQTARYSSNAKLGPLNDDIKACVVQVVGEDGKMRRDVPLSMALEEAREQGVDLVQVAENNGHVVCRLFDAQKRLFSLRKSAKNSKPKQDKEVVFGVKIAIHDIKVKAEQVRKFLAKGHKVKVTVKFGREFHLKQNALDQMVLIEEAIETDVGVRDHSPRDQYGGVYVHFAPKAHNVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJY7</accession>
    <name>A0A8K1FJY7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJY7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="205" mass="23139" checksum="C18A2B37E58D4DC6" modified="2022-08-03" version="1">MPSLSALSDALERLVASFLIPIDLRHVLHALPTGNGYRQIRRLSLRHANPNKVVRIAGVFASVETLVIDTQLSNQTSSTMKELPELDAQVSTRFERLTSLRLRGVRLANASALRSLRREMQILELTAVRVPDLAFLASPPFAKLVELRVEDRPPFGLAVDFAVLESLTELGMRRVRYCLLPSSRWLERLSLRLRVLDLHCSHLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJZ2</accession>
    <name>A0A8K1FJZ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000015">
        <property type="protein sequence ID" value="TMW66570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJZ2"/>
    <dbReference type="OrthoDB" id="122289at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="15536" checksum="D36B1CC5310A9A52" modified="2022-08-03" version="1" fragment="single">MFHAFCYEIARMNPRNRAELLTQLTLQLVVYHARQEPPPRQDEVLIALAASLAALVSTIEPISANSVAISSDAKLPSPTEALDTVKNIDLPKGITLSGTVEPIQAPASIKDAGTDAKNKKESDITDNQIAIANDKQDHQDHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK10</accession>
    <name>A0A8K1FK10_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_014606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000008">
        <property type="protein sequence ID" value="TMW66630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK10"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="171" mass="18979" checksum="01DBFEEBA13388DE" modified="2022-08-03" version="1">MQMRAIVVPRGSEGDFDDSRLSYVNVDRQYKFTLVDGRGYVTVENAETGKLINTDCLPVRAHDTRVIDPEGPTTTSPSCATRARSSNSCSPFIFCTKDDTAEDDLKIIRGCDLTATLNFLRDNADKVESGVSLAAPSYVDISKCEVLDCDDNNDDEDNQTRSLLLRTRWPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK18</accession>
    <name>A0A8K1FK18_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK18"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="133"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="344"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="561" mass="63875" checksum="1771955BAE730386" modified="2022-08-03" version="1">MASEATTDLVEAVVPRRELSDLFDNEALWDADDTDEYILKIASELEVTHAIAMIAMRDAGGNSLLHVAAIWNRPKVVEALIRTGVELNLRNSTNQTALDLAMHYGNAELGLQLRHYGSKHTCESERDLAIAQRDLAQQQLQETDAELTSALERLKHAKLEREAFRVERDRVAHTHATLVADLESLVEDRAHLQQAIDLLQTEKQQLLLQLAQLKEALQCEQSTRQNAVQSWQLAQTVIAELQEREDVCREREEEALRVRNEALKDRDLALEQLRLAQLDQGIAKQTQLEAEREREEVLKRLLAGEAVILAEKERWALKLAKVDEERRNIQHEINRQTTVLRTECERLEKQLAIANNLAWNQREELADKTTRLAQMESRLLHSEAQRERLEHAKNDLETRVQLLEDERRDEYKTWRNRIQESQRLAVVEDMHRMLTATISTWEAVANAHQQALLLDTDVFDDALKPILATSLTCEKPAIRPTTTSSCSDRGLNPLSLPALPSHSPVMAISSIISQHQEYNRRACSEPMLNCSALSGGVDFFRDEESSPFQETSKHARKDGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKB9</accession>
    <name>A0A8K1FKB9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKB9"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="256"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW66945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="468" mass="52957" checksum="955772E9135D02F9" modified="2022-08-03" version="1">MLMVVWLEHKVVVQYLLSQGFDPQQANVDGVSALDIAKYRKIEWLVKVLESNDRTFAEAPTKCRESRLWVTLLYGFILSGLFSLSYFLPWWIAAPLILLVLWLALKKIRKPHGHGGHSHGTKNVATLHPSKRDMVVTGSVVLAKPQKEPAFSKKHEPSGLSTLFKPQPEMIMGVWAAWVVLFIFFHVVVWVDPVYKFVVTDWEPFLYTLVGIEAVFLLTWFRLATMCPSDPGVIRTFQVDITQMLANAATGVVPPEASYCRTCMIRRPIRSKHCAQCGVCVARMDHHCGWINRCVGYGNHRLFVCFLLLHIIVVVGFVLLAGVVFQHFLQPGNLDATLGSSVMRVWMQVPDLVADHLLALMVFLWGIGTVIGLSFMAVQHLGNMARNLTVNESINWRRYPYLKADPKNNSKAADKLPRLLNPFDKGGWHNTLEFWTRSGSSALDYRTVFRLPNAVDEPEEPIINVQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKG5</accession>
    <name>A0A8K1FKG5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKG5"/>
    <dbReference type="OrthoDB" id="160631at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="408" mass="47165" checksum="7783C8B60B29DC69" modified="2022-08-03" version="1">MEPLASQPQPEPQPQLCETDVVTDSDVAAAIRDVERKEKRNARDRKRSQLKKQSMEEMRDLVRQLERAKEQLEARYGASLRSPSSSLSLRNTSENVSPNITTNGDTQLTRAQEQYLLMLRHIEELRRENREMTLDLAQRDLARSAVQNLLEHLEKQALVEYRADDADTPMMPMLPDDQLLEIAERVHRDIITALCHSPLMMPFTGAQVLGWTDFRSRLGTSVNFAIRKTFLHQSTEVLAEKTWEYISDGVKMRRLIPSYLSVEFNEIQRLNDNIMIIDRRTLDRRWLGPSKPGQGRVQPPLRTTYMLYRGRDEDGGYMLAMKTVDLPVFKANIAEGEMWCNVFYWIYLKSETLPNGEVATVTYFGGALKYLMEEIARDWLVELVFLAIRWESVAVSSSLLRFGDDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKK8</accession>
    <name>A0A8K1FKK8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_003931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKK8"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20540">
        <property type="entry name" value="CYCLIN_CCNY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="675" mass="75710" checksum="54ABF45BB77BD8AB" modified="2022-08-03" version="1">MSPMRVPLAMPAPLAVTVNGTHAHAVPSAASSSSSALPLQRATSAGNPPKHHSAYYGYSNNHAHHAQDMAFYQQRAALADATNQQLHRRQVPKRQATLAEKQYRQLQLQQQELQRQLQRQQLQYQQQIERQRQQQQQQLQTLPSPTRQQAPPKVEWRVAVDPKSKRPYYYHPVTRETTWKKPQELVEKEKWERAQFFASMENNIRAKLRAGNWFRESLTSRPGDLDDATLAEEGELVSPDTASTRSSWSSVSAANKMQCTSMPTTPEATLQTRSNQEEEEFDEAEAAMLAAADEIRPRLFRTLSSYETPVIGETKTLEDGRVVSFPSPIRERVRLAVMNDEDEELFMPRASDVESYTQPVRHSLVGPTMKTLSTSTASPSGGPMRAPLRRRSNSTSTIFVRMGTMNAPDQDTTIQCVATVLRAHLMEAQAAPIVVDVKFARFVNRHDQDANLIPSLKEIGLFMKHIFARAQMESECIIMSLIYVERLLKATMGSLQLQPANWRSILFCSMVMASKVWDDLSMSNADFSKIWPELTLKEINDLELTYLSAVEYNVRVSAVSYAKYYFHLRSMCASMGMLAAFDESAPLNLDGARKMQVLSEEYQKRSKMNPAPRRRSVTITTPSAESRAAEAAAKASPAASLEQLVHMEVRSAGGGMLSLMHRLSSSSSPSSSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLA2</accession>
    <name>A0A8K1FLA2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_009221</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLA2"/>
    <dbReference type="OrthoDB" id="67165at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="147"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="406"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW65054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="513" mass="57955" checksum="71792A8E3F7797CA" modified="2022-08-03" version="1">MVLNVFGRKDQTLSEESKQFINSLPSTYVNLFRKRRQLLPVWGSHKYCAMIKSTFLIYYRATNKPEESTTNCGQAPSPSLMHGFKYLNLQNCTIRLIDDDAAGYVFCVIPENGKGAIFFAAETEKDRAKFAQQAAAVQRHVPSITDFETLKLLGKGHYGRVILARGKADHHLYAVKEMKLNQVKAKVVYTERSVMEWVADHPFILGLDYALARGKSVFLISKFMSGGDLFLHMQNNGGCFTEDIVRFYGAELLLALEHMHNMNILHRDIKPENVLLDVDGHIKLADMGLAKRLESRTGRTKTMCGTDTYLPPEMVGRYPSGHGLPVDMWQFGCILFELRAGYPPFYIPQSSQKSTHQRILYQAVRYPNNISKDFKHLLVGLLEKKQEDRLGFNHGIAEIKAHPFFKGVDWNKVLRKETIAPLVPGPAGETLVNNFDPQFTEQPHQIYVADEVIGGYERDFAGFDYVRAGMPVEGPRSDTQSSSSSMSNSVKETIESSDEEKPEVDLETVTIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FM85</accession>
    <name>A0A8K1FM85_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FM85"/>
    <dbReference type="OrthoDB" id="165197at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="25312" checksum="E6461D746FB5A7EA" modified="2022-08-03" version="1">MPSCSELYGACVTGVGELNVRLKEPMSKIFQPVSIVSATTSQARPTNSTLMAILVQLAPITKCEVVKHSLKGSPVHEKCSFDMAKVEIYSLLMTLNGPKQWALDGFKHHSLSEEEREQIVSQYESGNYYGTNLAMGIFATPDLPLESVTDMGDSSFPRSRIGIFAVIACVTVSVGLLFHQRRRLQNGYAPILFMQKAGPTQGKKLSGSKHKTAAAAGEELSLKQESNERFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMA5</accession>
    <name>A0A8K1FMA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hydrogen voltage-gated channel 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_001306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMA5"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW69150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28469" checksum="3A21BA9804F1E929" modified="2022-08-03" version="1">MRLHDHNEITRLQSVLAKSKANTSAMPLDVDAAVLAFESQVIRVVFQLLESLSGFIEFFFLLELTVLFLTFRWRFLTHLGYMLDTMLVIGTIMCEIFTQSKTLRLLGIIRVWRVFRLVNTLVDRERRAHDLTREALDIEKARVFQLQTENIAAQESLKREYESRASVERMLQGFKDEADTLREALNIAARAVAEATMQGFVGELVEDELTQPADKPTDPPLPLETLVVESDEELDEQHFQDALTVEVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FS12</accession>
    <name>A0A8K1FS12_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FS12"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="18150" checksum="ACA88BB0CF163E34" modified="2022-08-03" version="1">MTMAAQRPPKPAFKSLQYFLNRSAVLAQYRQLLRITKPLERDVRRDVRQQIRASYEMYRHVEDETQASNLLRQGKEQVKHVSDLVDSAVARQRLVEETAQAKAKASVVVSSTSKATWTDAASGEDDDDQEDVRGRLGTGWPWKKDAPAKKLELDGVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C248</accession>
    <name>A0A8K1C248_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C248"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="175"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="388" mass="43379" checksum="A7DC3D728268804E" modified="2022-08-03" version="1">MRRNEWETAANAMPDAAPGPRMTQGDRRDHDVKAKHTESLRAMADSLQIARETAHTLSMQSEQLGRSEAAVEEAQYAVDLSKRVMRGMTWSGWIANAFTAPPQMESEKRKDGGDITMGFICPECKIVFKDADQLGTHYGKAHAEPHNGDSSRSARPSSMQATTNSSRQLHGDARQAREDVHDDFLRQLEPQLAELKQASLALGNALDTQNEQLDRLDGKVDRVHDGMKRISVQAKKLAGQKAPLTYRFRCAFQEVETRRFLRDVDGEPVLGADVLVDGCTFRAYTLGDDHEIWGFQSEQSSFFLGVNRYGNLKIRGNDLQSYEHMAIDHDKTVTRLFCYASYFGIGGWVVRSAGEKLTIVRGSVENKPSAAMFKLLNLDQIQAALDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2F2</accession>
    <name>A0A8K1C2F2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2F2"/>
    <dbReference type="OrthoDB" id="162677at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439:SF440">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW55190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30624" checksum="EEA7759CD78C64A1" modified="2022-08-03" version="1">MTIKQSRFIRRLVEKYNQTDATPVVNPCDKGQLATKVDTEPSTSERERMSRRPFRSLIGALQYLAMGTRPDIAYAVSYISRFAEEPREVHWNAAIRIVHYLKGTVNLGITYKGNSGSVTFVAWSDSDWASDAQTRRSTTGLMLTMNSGPVVFKTKLQRTVALSTAEAEYTAISMCTQEVLWVRALLEELGHAQVRPTTICTDNKSAIAIAKNVGYSARAKHVDIRYHFVRAHLADGDIDLQYVPSASQLADFLTKPIEGKTFQRLVSVCGLKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2H0</accession>
    <name>A0A8K1C2H0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hpc2-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2H0"/>
    <dbReference type="OrthoDB" id="68076at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014840">
        <property type="entry name" value="HRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21669">
        <property type="entry name" value="CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21669:SF28">
        <property type="entry name" value="YEMANUCLEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08729">
        <property type="entry name" value="HUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hpc2-related" evidence="2">
        <location>
            <begin position="120"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="55129" checksum="B4A6529833C13ED0" modified="2022-08-03" version="1">MPAMPALSTSTQPLVKKRKVFYVQLSPTSCTEVNFKELVKAQGGATSVPPRAIDTSPSDAESRPDSPFPGDTGAPSLITPRTQRFNIIERLEKRYGGGAVVGPPVHVADGADDDDDDTASYKRGDDDDLYDSEDSFIDDTELQQNIEEIHTQARVKTKHSGFFVNAGDEIETIERQEDEAMSMEGTPVKKPKKAAKKGGAESSRAVKAFIDEWSEAASEWQPGPDVLEAMEALRRAVHELTATTSFTKVFPRQLDDALRVVDKLVVDAHPNKWRVNGYFATLMTFLPFTKQYLKSNMLRLEARDTARAAKDVLENSAASLAKQIAVYAPRVEAESAETLKEEILKDKELALSLHQLLVIQDEWIVKENDYRQMLKTEDKKHLKEQDFVQLNPRQERNRIFSRILSFFPTGLMDIPSLRALNRNAKAKATRKAPAAKPATKSPVPTPKRKVSATTPVAEPATATTAPAKRSIKPFKSRMMDETPPFTEADFDEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C329</accession>
    <name>A0A8K1C329_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_010430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C329"/>
    <dbReference type="OrthoDB" id="79743at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035425347" evidence="2">
        <location>
            <begin position="20"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="684" mass="66862" checksum="FBF896ECAA89C881" modified="2022-08-03" version="1">MVKFRQAYLLALSVPLTIPYFLDVTIPTECSGYNKDAWQSVNVNATGVFCVRADHKICAADRKDGECPGPQTNLPFGSYCAPLTDALDVYGCVPSRYCGDVGGDQPLTEEAGAAVGAAAAYGAVHDGDSKTSVAVNYGVKSGTSNGGATYEAANGGANGGTVYDKTHGGDKPSVGGHNDGEDAAPDVLCDVAEDAPTSAPGATGPTESAEAPDSGLGGSPGAAPQSHDATYPGAPGQSAPGQSTPGVPGQSAPGKSAPGGAAPGDAYGGVPGSNGPSYGSDHNPASPLLTPSPALAPYASTTTPPSDGNGPYGPGSTPATPSPNTPGSEPTGAPYGSHTGTGAGPSTGESSSGSPSDGYKSSSVPGNTPVTPCPSSTTESGEAPSGSGNEYDGHGHDDSSSSSGSSNKPSYSTHKPSSGSAYSHDNGSESTEAPSTDGSTSHSSAGYSPEPTTPCPGKGGKGGSSSSSSSHDGSAGSAYTKTHTPSPSPSSDSPAPVTPAPGSVSGSASSSSTGGDGSVGSDATPEPSSPETTAPETPGPETTAPETTAPETPAPETPAPEPETPGPETPAPEPETPAPETPEPETPEPEAPAPETPAPETPEPETPAPETPAPETPAPETPAPETPAPETPEPETPAPETPAPETPAPETPAPETPAPETPAPETPAPETPAPGRRLRQFFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3E2</accession>
    <name>A0A8K1C3E2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_013298</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3E2"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17484">
        <property type="entry name" value="MFS_FBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004324">
        <property type="entry name" value="FBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00788">
        <property type="entry name" value="fbt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF6">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="541" mass="59268" checksum="0C9B7F79D63B22F0" modified="2022-08-03" version="1">MEENDGIRGRARKPQGATADESVAIDAGDDASLLKHTQEEDDDKKTTASTTLSTLQSVLNWWESLRLHFGDGLLLQIFFVYFTQGIRSTLCSLGTSYYLNETLALPPAQSEALRGTAAIPWIVKPIYGMLSDSVPIWGTRRKSYLLIFSAISAMAYLALSVPGLITTYHGALVALVVASLGIAFCDVVIDGKVVEAARSEKEDMAGNLQTLSWLSLSIGSVLGSMVSGFTLNTFGPLGVFFISALGPICVMFISIRLPEESYRFHGNQGFVDTVVTQCKILAQVVVDPICWRPMTWIFISNALPPSIGEAMFSFKTNELHFTKSFLGFISTVGSLTLLGTTAMYNAYFRDMPFRTMFLRIQIASALVCFAEYVLVARWNVAFGVSDRFFIFGDEILSDVVARLKHMPSLVLCAKICPPGIEGTMFALLMSIYNFSWSAASYGGSWLCTYLHISKADFSGLPSAVVVRGVAKVVPIFLLFMVPATTSIHSAALGSTALNSKSKDDDLESGRRGDDDVDPDMESDEVRLLKQEEETVQMQRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4G8</accession>
    <name>A0A8K1C4G8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZWILCH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4G8"/>
    <dbReference type="OrthoDB" id="74487at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018630">
        <property type="entry name" value="Zwilch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15995">
        <property type="entry name" value="PROTEIN ZWILCH HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15995:SF1">
        <property type="entry name" value="PROTEIN ZWILCH HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09817">
        <property type="entry name" value="Zwilch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="722" mass="79897" checksum="E29E940EFB9D3D69" modified="2022-08-03" version="1">MTWTSALARVLQRAEPPLALVEKDALVLLRVDAPRSFHPLHAFVSDEPSDESLVLVLRLHPELTTLLQTLRSSQPAAQDTDSIMERIVGGLVWQQRSSDATEYENLAVTTVPFFAEQVVHLTGGAVCLYGDDEVDALDALDKVAMALAQQEAVATELTSVVVVVEHQSGYAGRRFVFEDPTTTDLQPQVYRIHKSEWTSASIANLSLDDALEAYDAAFREHCEIHGDEEPDRRRTLDVSVQAAFEVRGPGRSAASSLAAPPVCLISSWTGIENVRSLLCRPAPQSSSVLCFSGARPKEPVSSCSSSQPRQTLVALECLEKALRSGDVASSWTETHDSSSWASEPMLVLPKFRRFLEEAHNSSQPQLRNSDEYLTGNEPATNNTIESSISVTLDGEHERQRNGESRADLDFVERVWDFVVQHVSSTELVLQSMHEFAQFLSVARVFPGVHPGNDSILAKLVRCRQQELHDDHMVSSTGPSPSFTDAAEKLLANPLDIVTAVIEVGEWKMKRDVEFWLGQTGFSAQESGDFVRGLPRFHVEQAPATSHWKAMEHVLELCRLGRSISLPVASMRQLVHDCVACYGGTETDLAATPALMVELQSFIPERLRANIADPLFWDLFMAFSGTFHHRVRLCQEAFHPSAPSLLTADATPLTLDHKTLQSLRRCVPESVSNHPDVVAMLSRLEQDHETRAQSSRPLFGGMDLSLTAMTRYDCTTRTLNVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4U9</accession>
    <name>A0A8K1C4U9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_006581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4U9"/>
    <dbReference type="OrthoDB" id="75078at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456437" description="Acid phosphatase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW56571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="59696" checksum="E8ABA0A7F7B4F4D1" modified="2022-08-03" version="1">MRLTYVASFAAVLVGSAAATLRQVVVVSRHGVRGPYGMGADTPSEELIKKYVRNPAIDLPLSAKAWGTAETEDPSEIVSPKLTKHGYRVVERMGEYFRQHLYRDFLDDTTCPQAYAYADANQRDNLTAEALLGGSFPACKEIVPTTEGTRLLFEQGQDPTATCPVCSRTVYEGIAGAPDCRYLIQESREEIEELNSILDCCAPAACVSEGGNDTNASTCSFFDIPTTWNGAFYQPWKDPLSSADYFSEFLLLQALNNMTLPAELPFEKILSLSKIHEAHMDLVTNEVNSANFGATLLAHMTASFEQTATEKAIPLPDGEGPTLTQSLDNRFLLYTAHDINILYLRNLLRLQWLTDGWHPHQATLGGMLIFELHTSTDESPELKVARKLKAGVKQEDYYVKAYFVTASPQQMRNEEVLSASNPPYVVPVMIPLCSDDVILPNGTIEVRCPFKTFKSLIGRTLKKECVADTLRPFVKSLSDNGSDPSDNSGGVIHLSTLLWVVFGVLIASFLVIVGRHFLIRRRHPAGVQKAEYGTVPQVSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5P8</accession>
    <name>A0A8K1C5P8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IBR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002823</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5P8"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="IBR" evidence="5">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="115" mass="13044" checksum="6F399F79938A2807" modified="2022-08-03" version="1">MLAPVRCCRKELPIEYVKTALRADKEDLKTYLRFLKERKWTESDLISDAEYATVVKSMGAKQCPGCGIGVERDFGCIHMRCPNGHEFCFTCLRVWQTCNCALIPQAEINAILGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5W0</accession>
    <name>A0A8K1C5W0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_006868</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5W0"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF291">
        <property type="entry name" value="IP11374P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="360"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="403" mass="44123" checksum="2D90FCB1F99460B2" modified="2022-08-03" version="1">MDEVKTPGSVDADPVSTNMIQLTTPPSARSPSRFVLRKSSGSSSSSDSTGSPRKKTGFELPRIRGNRPQVPGVAQKTIVAEEKQSDGGYGNSFALFLVLSYIGVSILYYHFVENWSVVDCIYFAMVIVTTVGYGDVIPVKTAGKAFTIFFAFYGIATIGIALGRLANWFLSRQQEIAKQTTQRLLSHVDSAADSASITKGEDPVKTKENTVPVKTHHKPTHRRPRWVRALFSRSNRAIIGAMIPILISIGGGLILGAIEGWPILDCFYYAVITVTTVGFGDFSPKSEGGRIYAIFYLPLSVVSVAHGIGSIIEEIGKRKVMKSTISMKELLAMDSDGDGKVTKLEYLSYMLVKLGKADQSDIDGIIAQFHKLDKDGSGELDKEDLERLDRQLQQQQEQQDSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5Z1</accession>
    <name>A0A8K1C5Z1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5Z1"/>
    <dbReference type="OrthoDB" id="165536at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="191" mass="21343" checksum="E9474544A71C5095" modified="2022-08-03" version="1">MEKTTNAKNAVAKSKPRQDSGYVVQLVMREPDAPYRLRQSRRHGMLHVNTTTQEVSIRYPKTGPCLFQRRVMQPRKCIMGRQVMKLFPCQASSAFMSRLVSAHDVPKCRDALRLIGVGVIDATLESYCIKKPEAAVVQARHGNIYEGPMQELSATLSDPQRAADISAWLTEYSQSQQLEADIASISSALFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C622</accession>
    <name>A0A8K1C622_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_003174</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C622"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="504"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="540"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="585"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="622"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="788"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="864"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="864"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="894" mass="101922" checksum="81FA71097D380840" modified="2022-08-03" version="1">MPMPPASIRSCGSQAYVSSFIPTSNPFEPRSVQDLISSMKSYASATDFVRTYNDVPSVEEALATLERAAVALKMRRYRDALKLYLEGGYAMANVAERQSNPKICNLLTSKGFETLNWCGKLCDWIEGRVDEKYPRPGVHKVGIPVAAWNEDWIGPNIDEEEAKRLWYTPVYCPNPVDFTNNGYRLRCVEMQRRPRLMICITIYNEEPHQLKATLRKLSNNLAYLKELNADKSSKKLSGTYSGDDVWKNVLICIIADGRENIHPKMLEYLDKIGLYDEDLMTINSAGIGAQCHMFEHTLQIMEDGKHLMPMQAVFALKETKASKLDSHNWYFTAFAEQIQPEYTILMDVGTMLTKSALYHLLHAFETNQQIGGACGQLTVDEPYRNLSNWVVSAQHFEYKISNILDKALESCFGFISVLPGAFSGYRYEAIRGEPLKAYFQTLNVELDVLGPFTGNMYLAEDRILCFELLARKNCSWTMHYVKDAVARTDVPEDLVSLIAQRRRWLNGAFFAALFSIWNWGRVYSESSHSFSRKSFLLLYYVYHLASLVFSFFLPANVYLALYFIVFQGFQQNRLVFLDTSDYSEYVLDFAVYFYNIVYLFGLLMLIIIGLGNNPKHMKLTYYFVSAVFGVMMVFSSLVGLGVFFASPTTTKSVTVALLTVGVYFVGPALYGEVHHIILTFTHYTALIPSFVNIFTIYSFCNLQDLSWGTKGLEEGPALNPGEDNEKGDFKDVLAKRKAMEERRREFALRQDNKKRQFEAFRTNILLMWAFSNVIFALAIVSFSNASDYLPVLYFTVAVINSTRFLGSISHLIYVKTDDFQNLVCSSEKSGHGKMARIPKDVDRTLEDHYAALMEDQRDFISRRNMSTNTGSSMGITPRRAPPTNEPPRTNERFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6Z1</accession>
    <name>A0A8K1C6Z1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="65"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="101"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1999"/>
            <end position="2032"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="2124"/>
            <end position="2155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW57573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="2407" mass="263656" checksum="D773F1FC512F727F" modified="2022-08-03" version="1">MGVGPSTSAALQWRDGDEIELLRETREFARWSLSDVTQLYRRFQKTYGLAITEPHFEDLLLQNAPESVSIKEIFRALDTNKDGRIDGLEFLAALLCVCRASFEEKARFAFELFDFNANGSLSLTELALLMKSVWVGMCLLTGHSHASSSSVTTFLQLAQHAFERYDRDGGAALQYEEFIEWARSNRAFMLQIEHFRLIAEKAVGFEETLSLPDGSDVDSDLELEGPVEPSGRAASSSFSPITPALPPSWLIEPSDVSPPTPTMFPPPVNLELEWIYGYTSRVRDSVRFLASGDLVYVVAHYAIVYTASCHRQRVYAQHRAPITCLDVNSTQTVVATGDRASVIHIWHAATLECLAVLASFHVDGVACLAFPAAKSPQMTAPLPGGVASASGVGTTAKKQLHAADTLLVSIGRDENASMALWDWHHERLVASGRAVHKRKRVLSVAVSADGREILVVGEHFAVFHHMDGRFFKLKKPSGLEPLLKTMPMCVSATYMGPSLAVVGTARGELLLFQNQQLTRVTVAHDVDLSVSVAFLAYRAMVLFTAGKDGVVKQWDTTLQPIGTPLALHTTLQTLRGLEDEDFRVHSMAYDATHQQLVIGTRQGHLLLVHEGRDASEPPRVLASSHREGVGVEALACSRFGAVFATSSASDRCLRFWNMRKRVQDAAFKLTFAPSAVVFSMDGDYVAIGGVEGSVALLQGKQRLLVHQMRNTDVMVTCLRFHPSMTSVLLAVGRANGLVYLYTLDTQRRFHRHALLKPFSRLETSLEDDLQADVSVRALDFSVDGRFLRSQHGGKTLRFWRLESLDVTRVTTLASIRNVLWQTQSCTLGWHVNGIDDPETTALRANAARTMLATLEHDGSVHLRAFPCADSGDLTRSVAQVHQTGPQRGQIGFARHDTLLLTSKGDDGSVVCQWALVPEQPDPQPRAHIDKDGIWSRLSALGADFEDEFDFDNPCERSISDLPASHSAAAALSVSQAPLGRSEAPDLDLALSYVLGFNHRECGLNQILTLQGQHHTAIVYAAGTLLTTHHLQQRKQLRVVVSGLSHKITSLVAHSTNIFAVAARHGDGKVLLWRWEPHPEPIATLQAPDSRWKHVLTAFDETQTVSATAVTPTKPRELAAVVWKRVAKTQTYALTIYDTHKPQYCLAQTEMTQLPVLFGAFDESDDAQIARFVAGGVDHVVFYRVHLATGQISSQNGVFGRHALVETALCGVSLTPFVVTGMASGVLVLWDHSVAAFTLPLATSDRKENGKSAVVTLAAVESRHLLVAALHHGAIVLLSYATESDRRQTRAHSFFQVLRQFYLTDITGPPPTFSAENTMIRTVSVLEELHGGILVVLSDGVVLHVDGHALRSDKTSEKPSARLVLNNGSGISSSALHPKEALVALGYENGYVRVFNMESHAMIREMTPEAGFGGVKALAYDSVGRLAASFSDGNIALLDEVSLKRLTTFPCGDAKASSLRKWCFILRFSPREDPMWLAAACRDYNIYVYRGTVGETPSFELTHTFIGHTAPIRALDFSLDSRWLQSSTDPRDRQLLRWRLQADETEKEPPGDTHWYSWRNAFAGPTAGLLETTFGPTVTCVDRIHGLFEPDAWYSPLPTLVIGTDTGDVVLGWYPLPCGAAQRAMFQEYRGYYPRNSLIRDVRFSNANHFVMTRDLSGICLVWRTDIEDELRILKRTESTAVLDVPKTESRPPETPLTSLDTLLSMKKDQEDVGDETLSVQPWRGAIREPSIVNVKATAEVPTADLVLDFVYGVNRNVLYPMRHDVLYADDTFEIVYAAASFGVVFNTKTKTQLMNASHQGQLITCVAVHPRGDVVVTGELAPNLKTQPRLLAWDANSGSTITQIPAIHVKGIATLAFAPSGERLAAIGLGDDHLLALYSLTQGHGVRVFTLLAHMKTSKEHVYTLCFHLENDQELVTGGKHHVLFWTTAASGSGSTHTTQTLSVKKGVFNGGKSGASPHAVVLRAVYVQAALHAVVVVTAQQDGSLYVWKARQCVDVKRHAHTGPVNALVTDPKRANLFYSGGHDGLIQVWNAQLECLAQLDVKKLAESATLPLVSGILTSLAVRDDRILFATDGGDIAELVPEAHEGARAPHHAGMDLRALTTEAMRLNIHLRSHCKGELWGLAVHPTTLQFVTAGDDSTVRLWDAPSREMLALYRAKTTAKYRAAAFSTDGNHVVVGTQDGQVTVLLAEKLASVVTTWKCSARPIAVLRFDPENTFLAIGAHDQTIYLYDAHTYKPKGVCRGHSGTVAHLDFSKGGTVLQSTSNAGELLFWQIVKTPERETNAFQQIKAATSVRDTVWASWSLPYGWPVQGIWPSGSDGSDVNAVARSGDHAVVCTGDDFGQVKLFSYPCVASGAPAKTFVGHASHVTNCCFSRHDRFVLTTGGLDNALCQFRYVAMPVGATKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C788</accession>
    <name>A0A8K1C788_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C788"/>
    <dbReference type="OrthoDB" id="148089at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="393" mass="44953" checksum="19C2C7F6578107FE" modified="2022-08-03" version="1">MLSTWEEREGYSPLDERLPALAPVIAPLSKDEKAARQRLHVRRTYYRKLNLLQTLRDEVNQLEAEYERLVDKRQRDETYESVAGVTDLVGPDKVLADKYANLAEMKGQLRRQNEAMRVALLEYTQVAQRLQMVMETEDLTDAEHSGYSSDDTVTDLAMQRRSSLPSVMLPSLKTPVTLELCYEIGQRAYSEISWFRSSPHFITSGVSVFGWRDKRVRDGERVKFMLHKTFYGITEFDLSLRSWSVIGSPTRMKSLFSPAMRPQVLPIQVVDEDNVVMLRQFSTPDGKVVVESVFLTTRLEVPGGHLIVTRSLSRDLLAPYVPMDTTHHQWDDFFVWVLSQSSGEHGQDCTLCLGGEFDVLMTVGSEAWLMELLFMVLRWETAVLGPIFSIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C791</accession>
    <name>A0A8K1C791_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C791"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW57909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16984" checksum="6ABA477493F53BB0" modified="2022-08-03" version="1">MNERTPEKALPALEAVTSPLNPDEKAARQREHARRTYYRKLNQMQALRGQMHKLEDQYERLMEIKRQKEELDTVSGLSYLVGTRMDLSELYADITDVKERLLKQNEALQAASRDDHEFALKAQKWLTDADDHDSLVLYSSSSSSDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7X4</accession>
    <name>A0A8K1C7X4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NFX1-type zinc finger-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_011902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001660">
        <property type="entry name" value="NF-X1 finger and helicase protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046439">
        <property type="entry name" value="ZF_RZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20173">
        <property type="entry name" value="ZnF_RZ-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51981">
        <property type="entry name" value="ZF_RZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0391">Immunity</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="RZ-type" evidence="11">
        <location>
            <begin position="1891"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW58314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1963" mass="220535" checksum="59CAABCB36BFA001" modified="2022-08-03" version="1">MMQAPGRKKQSAVCRHFAQGGNCRFGSTCRFVHAVDGGGGSRKDSTRRQLDAPTPSTTTTSSFSLAELRRVLTEQLHRDLVMNAHASDALVVLWDKHPDGYKQDVRWKPFLLVETTAKPRTLTTSNDAMIFVNSALQALRSPSVAPEFIRALGERGGMGVEILERFVRFEYSESAGRKRDVVSFQRGLVPFLMLLTSKRLDQAARLNVQAANYVYSCVVEHRQELFGKYIERLAQVVYHGNIEDIHLSHERFLQDSFGTQFAPLCFSQLVLPFLILLELLANKFREVAYDELFPRTVKKVGELVLEWIVDHEPDDLDSAHCFQLIQKAIDRLLAISTRSAVAMRAGQAMAARQQRNAQGVHAVDPVEQQWNLMPVVPPGEALMDNGAFGPRHDNDKMEIKEISILPTTSEVFSPHTPALPGNFAFLDGAHWLPPGPERWIDTHFRLFREDMCQILRESLQDLAGRFENSKRFNVGRVKGEKVDFSLYQISQYGLVMLHTGSDVKGGYKLRQGLCVDLEFPLSTLGTKFKERDRAQFWDRSGRLRRDSMVAVVSYASGSLEVVFSKVVVREIANLVKDPAKISVQPYSSADLKVVRTWQQVGASIFLVELNKLFFDSYEPVLKALQEVSAFDIPFLDHLAPVVPMQGGRMDVPQYCLQPGFRFDLSPCLKGNRRVHLEPDDVQSRALCVQNLVRESTLEKDQAEAVVGALCSQVACIQGLPGSGKSFIGNLITQVILKANVTPILVVCYTNHALDQFLCHLLDSGINKIVRIGGQSKEPRLEPYNLSKLEKPPHGRELYYLYSQLDEAAEDLNYVYNELSGKITWRRMRNFLEDEYPNCYQQFVERDDQLFDDGWNVAGCDNVLDYWLDGIDNPPPRRGRQRNVDLHRGDIWSWSVPERKQVYAYWQRELLAGREDEVVKAQKKYDRILTELNGVRNRADADALQNAQVIGMTTTGVAKHRQKIAAVNPKVVICEEAGEVLEAQLMACLTPSCQQMILIGDHQQLRPHIAVYDLSVESRRGQKYRLDVSMFERLVSQDSGTGVPMWTLTEQHRMRPQISQFVRTLFYPRLRDAAETEVYESVKGIDKNVFFVNHTCPEDGAAAKDQQMAGSIRSHSNALEVQYVVATLRYLLQQNYQTSDIAILTPYVSQLLAIREALRGEFVIQLSELDEAEVKQELAEDELAEQLSDTRAKMQGATQTQLSKAIRLATVDNFQGEEAKIILVSLVRSTIQKGEEGRSTIGFLKIPNRINVLLSRAMHGMYLVGHGALLREKSEHWRKVIEILEEDECIGDGLPIHCQKHPDDHRVVRLPKDFKVEAPHGGCLRPCGLRLPNCGHICQLMCHSDQPTHETVYCDKPCARLHNGCGHLCPKNCGDKCGRCETVVGNITLPCGHGHSNTKCWEALSPSKVYCRTPVEKVVPECGHTVKVQCGDTKLVCKQRCGTPLSCGHECRRECADCTRSTVKAMNEHSERIITPITRTEHGACQKECGRVLSCAHRCQGVCHPRTPCPPCSSRCDIFQCVHGGCAHKCSTMCSACCETCEWECEHQGRCELPCGSPCIRRLCDERCSRILDCGHRCPSICGEACPSVDFCHVCADADKKQKQVDLIMFQSYEEVDPDEDPIVVLPCCRVMYTKDSMDGVVGISRAYSPEGLPTALPSELIAMPQCPNCNRPIRGINRYNRVTKRAAIDAAEKKFIESSQRALVELQSRLQLMLTKKEAEKDKAFVKAVQKFARDTKRPPCQKAFEACVAALERSGQSMAQELLPVPNSKFQYGGYSNLLLAHYYLRIENVKDAEAFAHMAITRFVDGGFSIQLRETRLVLTQALLLKAREVLTNVKEIEGRVDAIDSICEEVEAQLHELPSGYQAAVVNGVVEETRAMRLRARGPFYEEVTEDERRSVLVAMQVEFRGTGHWYRCPNGHPYSVGECGMPMQESSCPECGAVVGGSDHTPAAGNLHYNAIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C837</accession>
    <name>A0A8K1C837_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000112">
        <property type="protein sequence ID" value="TMW58189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C837"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452360" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="360"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="678" mass="75686" checksum="CB10D68752E95B95" modified="2022-08-03" version="1">MRTLSWLGGLVLFATSTQARTVRYAVTDVFMVEADSMEGALEMCQMNPNAVSVGVDWGNENNRAVVQLCQRRQRVEEIHSSRHVLQQIAVYDTPACPTSMELLYQVSEGRVVCVRRVAASVALSSGNYISDLWVSAERHYNNDAVGWTTIPESVLSPANGILRSIWQWVWRASYRGAFISYQRPVVPVTAVRLLTGVDASIFRTACFTWLGDQWEDAGLGYLDGSHGKKSQLCVRRGENADNLALLEATTTTDGCPSRFSQTEKLENGIKLCFRWGESTASDSPIMGIRLEPSSGKPKATLPGGFQLVSPTNLNRGSEAVYLYTTQATSTTVPLPAPLNRPPLVAKHITGVDGKPEKLTFKILQLADLHYSGDPTTSCNDKPIGMAECSEALMTQFVNDLLDSEKPDFVAFSGDNVQTYKASLRQAAMDAATSGVEARGIPYAMIFGNHDDQRGFTREMLMEMAVNKQHSYSQRGPTQVYGVGNYELNVKAPTSGTWGDVDSDVFRMYFLDSNAYPDRGLLPNEDTKYDWVHPSQVAYYRQLSASHETKVPSIMFFHIPLPEYAMDARSLRAGEHREYVQSSEVHSDLFSTLVELDEVKATFAGHDHVNEYCYKRESVQLCYGGGTGFGVAYGWKEVQRRARVIEWTVDSTNKREIRSWKVLYGQIQQRVDEQVLYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C907</accession>
    <name>A0A8K1C907_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C907"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="46321" checksum="A961A4401E80E14A" modified="2022-08-03" version="1">MTKDFDIILFGATGFTGQIVARFLLQDAESAVDGPNALKWAIAGRNAKKLEDVKRTLKQKVPSVSASIIDSIPVVVADVKNEQQVVDMVKRTKVLMTLAGPYAFYGEPIVKACAENGVHYCDLTGELLWIDKMWGKYNDVAKKTGAVLIHSCGVTAVASDMAVALLADSVRKNKQSETSAVTLCYTQMKGGLSGGAMAGVFNMMETASMDDLNKMNDPFFLTDAKTIERKNKAGLTKLNTGSFGIKKEKDLKLWSSYFLYGGANSATVHRTNFLLNDAYSDKFVYRERSAIGGFFSQIGNTIGTSFGGMFLFFKWTRALIKLSTPKPGEGPPEEEMKKNEFSAKAAAYDANGKLAARLTMAGKGDPGYIVTSYIVMECAIALAKGEFAAPCAGFQTPASALGLNLAKRLNDKKIVAFDVKTSRDPPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C971</accession>
    <name>A0A8K1C971_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C971"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16664">
        <property type="entry name" value="RING-Ubox_PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045210">
        <property type="entry name" value="RING-Ubox_PUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="270"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="5">
        <location>
            <begin position="433"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="396"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW58493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="539" mass="58890" checksum="B8E26C79119E698C" modified="2022-08-03" version="1">MGGGDAMVQGLDPRYVRFPDMYRLYDFHVGPKKHQQRSFQGGQMILFVRSPDDDELDSVQAIQVVGDDGEPITNPKGKEKEGAEEDETPKETNADFVVLYVSGDKIVLDKATLNQPNNDGWTPLHACCHTQNAQEAGITILKELVDRKADLSLVTRRGPGSFACGFTPLHIAVAYGLEALALKLIRAGANVNTKNTIGWTPLYDACHRGYTSVARELLKAGAKHDVICPEFALCPYPGQYPLAEAARQGAVDTVKALLEWGVDKNAVNTLGWTAMHEAAYHNRVGVVKLLIVYGADVLIKTKKGSLARDVTISSEIRGMLEDITTAALAAASPKREKTAIQDGSGDVEAEKPSSPKKSPAKTVPLSRKEEYTLLGDLPNLEARSAAPTIAIKDADDAADDEDGKADDEDVAEPSTASTTKHKKKRKHKKHGREVPPEYKCAVTLKLLKDPLRSPYGQVFEREVLEAWFRDFGNRCPLTGQPLSMAEIIPDDKLRAEIRNWKRGTRKLKEGGQDITPSEAKGEAKMPDPVAAAADDPYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9C5</accession>
    <name>A0A8K1C9C5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 206</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_010127</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP206 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9C5"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003356">
        <property type="term" value="P:regulation of cilium beat frequency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021897">
        <property type="entry name" value="FAP206"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12018">
        <property type="entry name" value="FAP206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="420"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="665"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW58568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="704" mass="80510" checksum="338E71B4379E1B71" modified="2022-08-03" version="1">MDQAQKIIADIVARCKYKNVEVSETLAAFTARMIVHKSKRKLILEKEMTSDDMHFLIDRCVHVLLQQHDPALETVRMQLEFDYTYAHLEEMLRQKRDRKEKSVAHLERNIASLVPQKPSDFETLTTLYRNIFTLLMLDADATDKPADRYVEKEVATALESVFPRIGLKTFVTMSPEDKRFQLEELMRIVEGIRLFNKELGKGGAGIPVGVDTIQDQMLTLGRMVKEEVNDANEVCTQYTDVLLHVHHHEPEHPEDSELDPSVETIQRWQVELSNRRQFLSYLQSLEEDIAFSCEKMDAMITTFRNDMSALKNLVGSRTSLPKSQVYPLFEAVSKSWRVLIQEHELLQARSRSLKALMQFKDSFPRSLNGDSEHWRRAKKRGTIPAEELFEQVETFAAEETTASRPGSVHRTSFRIKSSFALSDDEEKGDDDYDEGNPNEEEGATMPIRMPVDSTPEFMQLPLEYQGFCPWTIVERGGLLLPGDPSLGVVQYQNAYHVFVNKRAVQEFMLHPRRYVQGILRLAAKQPSLIYLLRLQDGFPNTDLSSLLKISSRFPSGTPTSAMGAMAAGIHPLLAPPPAQKVDASTSTPTHFVEKNIDYNYEWNEWSLRRRALKIANLRHCKTVSCQTNLSHFRREVDTQVYLPTENTTQTGKERGTNPPRVTTYFAGLRNGPVYTGNEDDDGKEDEESKHSEDRPAIISYTFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9G7</accession>
    <name>A0A8K1C9G7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9G7"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="217" mass="24145" checksum="C34187505D705D3A" modified="2022-08-03" version="1">MTPMVGPGEFKTGVLAIEHGCIWMDIATGQTVSFHVQPTTGKYYRYLSDIMEVHWHTMDYLTIGNNIFLRARLFMKTFYQLEQSADGKKKLFWHFNQSDLGVDGALYVILIINEFLIVFINATDVGIVAMIVLRPLITSTMRSSMYNTTESTSTVATSAGDSSVEGESGRETPVATRKNSEKDSTLAKMLLYTDLTSVSLSLSLKSIESFYTCSIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9P9</accession>
    <name>A0A8K1C9P9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL11m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_007225</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9P9"/>
    <dbReference type="OrthoDB" id="1091498at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000006">
        <property type="entry name" value="50S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000003">
        <property type="entry name" value="Mitochondrial ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_uL11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="9">
        <location>
            <begin position="71"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW59080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="15523" checksum="9E17C52719DDCEEC" modified="2022-08-03" version="1">MSAVKGIVRLRVLAGKAAPSPAIGQALGPLGVNMMEFCKAFNERTAKHIDNIPIPVTLTAFNDRTFKFEIKTPPASWFLKRAAGVTNGSATAGQQEVGTVHLRQIYEIAKVKQQDEHVDYIDLESICKSLIGSAKSMGIRVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAA5</accession>
    <name>A0A8K1CAA5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAA5"/>
    <dbReference type="OrthoDB" id="58903at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033579">
        <property type="entry name" value="TMEM128"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20479">
        <property type="entry name" value="TMEM128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23695" checksum="6AC64301DF406347" modified="2022-08-03" version="1">MMDMQEIKERKRARPQGNEHEEAEAEAEVDPSVPLVDATGRRIKSKRSSIEKGIQYVVDRFWPTVFLTLASVGLYELRFVHALLYASHANRLFVNLFILCSTLVVLFGSYIEVYRNLYMKEKVSYETAKTSTHGMLLCMVLAGLFFIIGMWPVWGWLTLPYLFMWFWGVIVQVVVIFPVQLQRVIFGIAYFWFMHSYLSLFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAS1</accession>
    <name>A0A8K1CAS1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxisomal biogenesis factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAS1"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29395" checksum="8EF438C1C22DD651" modified="2022-08-03" version="1">MQVKAPFTSDTAIKVAFSLEGRDKINKIVQYGTRALAFYILSVDPKSDVGKRFSELYKVMQQARKGFRLGKSATFYKKAIQAMDNKTLSPYHKYLQLLQNWGMVGFFVYDNMVFFSKAKFIAFDADEAAKRGGVLWFFANIAGFLLAMDKLNADVEKEKCILDVLKTEEDPARVESLRSQLEHLQHDRFTKFLSVVKVTCDLVVSSNTSGIRLPERIWGNKLHDGIIGSVGCVSAAIVLYNTWPSVAKDVPAQDDDKKQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAU0</accession>
    <name>A0A8K1CAU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAU0"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03199">
        <property type="entry name" value="GST_C_GRX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007494">
        <property type="entry name" value="Glutaredoxin2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011901">
        <property type="entry name" value="Grx2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02182">
        <property type="entry name" value="GRXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007702">
        <property type="entry name" value="PRK10387.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04399">
        <property type="entry name" value="Glutaredoxin2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="232" mass="26596" checksum="1A9583BB32305D28" modified="2022-08-03" version="1">MTTQAPPLKLYVYDHCPFCTRVRFLLGVKGIDHELVFLANHDEATPINLVGEKKVPILITPSGKPLVESMEIVRYLDADHGGEPVLNESADREDLKKWMQALDSAAIPLQLPRLYTTPLPEFARSVSREYFRAKKEKMLGVPFSEALEQSPELIKKVNSFLEELEPMLRGQRTVNEELSYDDVDLFPRLRSLTIVKSIKWPTKVREYLEYNSKKGDVLLFDLMAQDGFRICV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAX5</accession>
    <name>A0A8K1CAX5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="1">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_007227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAX5"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000036">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF4">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW59082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="510" mass="54201" checksum="144A1A187CD4891F" modified="2022-08-03" version="1">MAATSPSKRQRVGSNGQPLVVADNLLNGTFVPASSGAYVDVLSPSTGEVIGQCALSTPEDVDAAVANAKSAFPEWSKLTIKSRAAIMFKFHALMNQHADELADIVVQENGKNKMEALASVMKGNETVEYACSLPQLAQGKTLQVSRGITCEELREPLGVVASVVPFNFPVMVPMWTIPIALTMGNCVILKPSEKVPLTMRRVAQLLLEAGVPPGVFQVVNGKEDAVTRLCDHPDVSALTFVGSSRVAQLVARRCRALDKRVLALGGAKNHLVALPDADNEMAAKDIVASFAGCAGQRCMAASVLLLVGDCSDLLSLVIEKSKQLTRGTNAGQVGAIIDAASRDRILKYINEAEQGGAKVLVDGRAWATEGQGFWVGPTVLLHASAEDAALHDEIFGPVLSVYPVGSMEDALAIENHNDYGNAASVYTSNGATAEYFQTRFRAAMIGVNVGIPVPREPFSFGGLYGTKSKYGDMDITGDGAIEFFSQRRKITTKWSAVTNLADKANFSAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB25</accession>
    <name>A0A8K1CB25_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB25"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035418316" evidence="2">
        <location>
            <begin position="19"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="521" mass="46522" checksum="801D96D946ECB487" modified="2022-08-03" version="1">MLSIRKICALALCALAVAGHSQVGASEATSSRHLRAQTYGKPEAQGNNGYGGKPNGGASGGNNGYSGKTGGSIGIGGNAGGHASGSSGINFGGHAGGNGYGGKPNGGASGGNGYIGQGGSIGIGGNAGGHVGGSSGINFGGYAGDKGYNGGGFNAGGSISGGISGGANIGGGNGYNGGGKGGAFGSINIGGQGGAGSNGYSGGGASGGIGGGAAGGIGGGASGGINIGGQGGINGGVNGGASGGIGGGASGGIDIGGGKNSGGYVPGNGNGGGKTPGGGAGGQSNNGGGGYDGGKNNGGGGYDGGKNNGGSPPAPVIPLPAPVTPSKGGEVPGGHSGGNGGGNSGGNNNKSPCPSSSQPSGKPGSGGGSYTKPTPAPTPVMTKAPGKGPGPVPGPAPGPAPGPAPGPAPGPSTPSTPEPKPSSAPSPVPSPVPSPIPSQSSSPSPDQKPTPAPSGKLTPAPVPSPSSGYTPAPVTSPTPSGSEPAPAPAPAPAPAPAPAPGPSSGKPNDTPSSDSPIQKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB69</accession>
    <name>A0A8K1CB69_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB69"/>
    <dbReference type="OrthoDB" id="168363at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="164" mass="18461" checksum="9079759E3E23F391" modified="2022-08-03" version="1">MSTAISMHSPDGRFGSHSHDLSPAFRHMSAAALWHRTSDLERMLELARSDEFSDDESDGEEESDDEEEEDEDDDEESDRFEDQSPRSVEDRRSEAPESETDADETVLVPFIRPMATTGKQQPSPQGSVTASPKGDDWTLVDKSPTFESLVHGQARLTETWFEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBA2</accession>
    <name>A0A8K1CBA2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_007392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBA2"/>
    <dbReference type="OrthoDB" id="157265at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="45270" checksum="96FAF1E1D6877AAA" modified="2022-08-03" version="1">MTPKPPKFASPFPPLELSAVDRAHLRAVARTFVEDTAEQYERFMREENGYVDPKRWELIRERENLAVYIDAESRDPKSEHYALPMLFTIGTVPGDLDDMVYGILNHTTRSMRLKTSYVQDQFVNCSVLATLLSPTPESPFDSLTVKWIVKGQSVPVQVIFRNREVVYLEATGMTTLSNGEQVGYQLLHSIDLNQTKPRSGVVRGNISICGVCRQKTPQSVEIYLRGFVDPKGKILRPLVIKSCADALLSAWHYMHFARMKKLMWFLRRRRTTAIEAKESEEDLDASCASCQYHFSPFGGRSKRVCQICRMTVCSACRVTKKLSAIGEDGRLLRQRIPFCRSCYDTAIHADAHEIAVDETEWRRSGSATGFKASHRSSLANFTHRLERFTEAASLTEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBU6</accession>
    <name>A0A8K1CBU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Condensin complex subunit 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_000379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10263978at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF1">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="7">
        <location>
            <begin position="560"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="9">
        <location>
            <begin position="1014"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1330"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1388"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1405"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1466"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1481"/>
            <end position="1496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW60337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1525" mass="169700" checksum="E05A798D63421646" modified="2022-08-03" version="1">MVTKRQLARNNTSMATLEKELVRALRALALQDVPDAAIKAVFDTGGTVLNSRREDAEFVENATLEELEEVDRVFHKYVKQFVGTQAAIDQRQDHHQHSSTLWTFLSGDAANTKIMGEEDERAHPYAAYRALFTLLHALISVGERYPSLKRDQKIDALNKALLASKTYLNWLQLPGGSAYGLFMPFVYRQVLDVIKKWADLATSTESAASVSGASQNDKTPRKRGSRKGNQVNRVGDEGDGYKQLVKLGADMLDTMVMFLQNFTLSSSKESIVPTVETVVYIQIVGCGAVDDIVVHATTQSQRIFEALLTGQHGEIIQIARVVIHCYIPGASFQDMAANETGRSLQFHKLAIEIIGMVQTKAIRSVTTGEDQDEDSVEQLSGLFLGLVQNISLRAPDRAEERQRVLNYVLQACLAPEFLEQDKICLARFLASYSKSAKAKFRQFAVELVGKLILEPSTWKVASSVPEEMESYVGVAPLLEILSERSNDKVSAVRAKAISAISAVLTAGLKSDSPSTEKNKQSEEEVATPDPNLISASLGELLYTLSEETGKVQETPLMLRLVELFREGIQDEKTYVRKAAVQALEALIVVRPGNAVHSMRHDVFDMQARCGDPSVIVRVQSVKSLSSVLLKFPEDEDVQRLWNLGVLPLCVDAETSVQSTTLEHVRTAIFDRISKWYYMRDNKDEHEKLSSVWVLVSHIQGVMVRCVQKGLRLLLKDGQVRPKTLIKACILAIRTSLANLEKDPDSDARFWGFSWIILEELARSGLLVEAAESEAHNLGIVVDCWNKVLEEELPDSFAEGSKRTLRVIAALSPVIDAQDAKAMADSILGNLHSFTIPIDMIPDAILALSSICKAKAPTLKKGREISFGWGKQLLDICENSLRTCFESEPEMVVDDPMLIQKQLICIGEIALLEFIKDEEKNREAGIKLLSIATARPLVQLFLPPSLVPNGALSSQAGEDGDSSPVARPKSVLIPIPVRVCAFVTFGKMCLRDQDLAKSCITMLIRELRTCKSADIRSNILVILGDLCIRYTALVDPYVPTIALSFTDESPLIRRNALLLFSQLILQDYIKWRESLLRFFLRAAVDSDEELSNLARHVLCGPLLQKSPHLFTNKFIEMIFVFNKNTSKLTIAERHEREGVEEIALPGQAKFHKRSQLYKFLLQNMTDEQKLQISMKLCTEVLEEVSDGKLKLCKNPSEITDFGTEAVLKDTFAILCSPDIKLSSGKDEGDEDGEDAAEATEGASVANQLAAAKGKLLSKMSKKNFLENIVPVLIGLKHKLEANRSPLMRYLLHYIRELFKLYGKEVQDILSADPQMAMEVEYDLRQFELQQKQQEPGRGGGNTTPTKTGQGGGQRTPLEELDPNRTPQLLPEGRARRRQSMPTAGTPAHPVRERAISSDEKNKRDSVATTLFFSPNKGSEQGKWQVKGSRSNYTQEALEENMQRTLVSAFDETSPPSSPVAKPHETQENDDTGSEYEEFVRLPLKKKQKQKSKKKTTKKKDASPPPASSDPLDMATPKVNRAKRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC68</accession>
    <name>A0A8K1CC68_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_000693</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC68"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000655">
        <property type="entry name" value="Protein transport protein SEC13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="52"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="279"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW60651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="382" mass="42154" checksum="AEFD5DA1656E670E" modified="2022-08-03" version="1">MKLLRSRKSSASAPTAQPAGPDHVQGGDYDQGSAYGGYHQEPQLQTPVASIDTEHNDMIYDIQLDYYGKRLATCSGDRTFRVYDVSNATSAPEAQPTKAKSKNDGTEENPGYVLQHIVQLPEDSVAPVHRIAWAHPKYGSVVAMACQDGRVYVYREELLPNGSQTHWQQKYVHTFHQQSVLSIAWAPYEYGLCLASASADGQVSFLTRMKEGWITTSYFLNSMDGAACSSVSWAPYNSLGSQGAQGPIQRVVTGSINTAVTIWEFSSESNQWVIVGQPLYGHNDWVRDVAWAPNVGVPANIIASGSDDHTVRVWSQDELGGEWKAHTVHTFKSPVYRISWSLTGTVLSVASGDDEITFWKQRSATEWVQISSMNEQGAHVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCL7</accession>
    <name>A0A8K1CCL7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Nucleoporin protein Ndc1-Nup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_000814</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NDC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCL7"/>
    <dbReference type="OrthoDB" id="67850at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019049">
        <property type="entry name" value="Nucleoporin_prot_Ndc1/Nup"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269:SF6">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09531">
        <property type="entry name" value="Ndc1_Nup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW60772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="68640" checksum="41D21364EABD7287" modified="2022-08-03" version="1">MGFVHALEVLHAVLKVSDAPTQRRGLSDTLELPFPHLQQRLQQSLRGVVLVGLFAVTLPLALSCVHVLPNPTFVFPGFVLFGLTTAILAALALVQLLLRYVMLPSPSRSFLSDQNSAVYGWVQTTICVVVEIAARLYQEPQLLVLFTLSIFHSWLWKSIVSLIFVASADIVDEVDQQFGTFAFVGGVVSFVSFVWLQERLDVDPFVLDPRSVLETALLRDSIRALRRGGLVWILGRALLFVTQSDSVTIFGFRYHRALFQITSNTIESFALLSTASIFRILLFRANYKALENVTSGGNLWDTLAAPRDGDQWFVDSLFAEHLAISSQSITPLSEQYIIALKTRMDHVVKTIAGKKVQGAPATFEHVACLEKLFKFTNLSVLTKFDVACRRSLYGSEKRWMSFVEVTTAVLDSFTLSMQLLNTVPERKNAGQEEEIAKLEKSLPNLVNFVLGNAHVHPLLLLDAHPHLSNLRISSSAIKSKVRYFVESRAQFAIRRFLIEEARRRVFVQAAVVQACQQVLCHLVSASRTEDVQGNVQHSVPAILSSLVECRGALESYIDMSSKIGNNGDIYVAYASALARGLDKGIYRITDAFYNELGSFGFAPNVKQALESYVSFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCU3</accession>
    <name>A0A8K1CCU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_000497</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCU3"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000079">
        <property type="entry name" value="mRNA decapping complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="107"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="338"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW60455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="47941" checksum="D08398F374CF8484" modified="2022-08-03" version="1">MGEQQKQRAKARGKGAPVPSMEEVMDELQSRFLVNLPVSELAASERLFFQIEQCYWFYEDFYADQFKHLQHLKLNEFAKLMFGHCPLLRPLAHQCENMFQDFKVYQSQVPVVGCMLVNAQRTKVLLVRNWKGTSWSFPRGKVNQSESDIECARREVMEECGYDVGETLSDKQYIEFVQNEQRMRMYIATNVPEDYRFAPQTRKEISLIQFFEFDSLPKKTWCVLPFMPRLRRWLNRDKSGRDKNGNGATTVKGRASSAPRNRPTAVAPTPEKKKVINERSISTPHGRPVARKGRGHFGTEFETATSYDGVNDETFGQKTAGFSVDEMFSVNERLTGQKFEYDGNPHDFGKPSTAGGASRGVFHYGPQSRGVVPPQILRRPSSSSQTPTSSGDESPSSPSEPRSKSSFPVFTFDTVDIMACVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDJ0</accession>
    <name>A0A8K1CDJ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDJ0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="131" mass="14663" checksum="814C3ED33A3751FB" modified="2022-08-03" version="1">MSRALTQLMGDTIELQVTQRARIFFPRAPSARFVHGSALKQPELSESGVNRVQKAMRDARDVMATIERDDPENGFDYTLQRLEHAVEAIEEQSKPSYVGSSECGGRVSLRFIAFELHVTHLVGSDTNFPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDU3</accession>
    <name>A0A8K1CDU3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10067602at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="1262"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="855"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1341" mass="150114" checksum="81DEF12B3828C81A" modified="2022-08-03" version="1">MRVVNMETTAEPKLLVPYVVGAKNARLGAFMTQAQCSIVYRPSDKVAQHSSEEELAASTVTVKNNNSTSDGNSKGFTMRFIISAETMRRVDHGIRLLQSAIETAEQFLRKRSNTNVDSGGKHTDVSSGHMGASSEAGTSTESSTIPNSVLSASTRHRKESNAGRDSVDQRKAQTRIEPSLPIVSEKAKTSAGRENLEHRSRKRPLPVSEEQKGTSASSKREKRDSTRSSSHEANTDRSVDDVGMAEVSLHVAPEPPTTENAGFDEFWIRLQRGIEYSKRLAAQSATARHRMLEEKAKLFKVVNSAQLARQQQRVADIVIRTQCAVMASSDSGRTKKRRIEQLGAAQRSCWKGSVIKRESVSAMKSDFGGPTFVNGREASTPETAFVDLKKQLIRFREALKPRKNDSQALSRDKDGKGDEHVQCPMPSTSTKSNSRHTSTLSENDPGIVNHDFDTAEASVEFDEPALSVLERFEEEDTNHKGEENRRDSFRATLIAPGLSRDLNLIQDYSDETDCRLLRFLTGQRQYFYLEPITLKYGLHDRKQLRESILSTKDVQLLCDFISEHRRFGSDLLKAVDALVLSPSAFSTSKAVNWSTIQRPLAEMHPLLLALHLLGQHYHALVALGEDASTNDDRDLLSSETLQPDLFKFMLRPVRSSAIESSLCDSLPISLVRETIVHCPEVVNHVLDWKDEDDVPRATLNDVTNLLSKTLTSSAYLEGLVTRLRAELQNADRTISELGRYLHYAQHRNGNRIIFLVNQFKTTASKLLVENTQLQIHKWTTVFVENSFSWFDQFEDIVDSDRSYDKFTCLQDALFVWQNEKILYSSGDEFGVQQLPGDDEYGGHNEFDLGYQDDLSHREKEKEPEKEPEESKLDELQRITPPELLKQVSEFSADDIKTFQMSTEDIVAARDQLNDSFTRMRESMKILGRTAPWRIHVKHSNLLKREYGKQMEVENRLILHQWAMFYKDHPEKLHAQTEELRESRGVVEGGKSPTPDAPVGVDSQTHVDYSGVFTSSDSSEVVEMKKLRHEIEFVASKMQTIDTASMNSDRKNLLDACNLLAASCVSALTKFLTHDESVIAESPKVPARQRQRANSTGSASVSKAVRASVTKLRKGNTSQEPTATKATKSSSSVSEKSNPRSEPAAGEATKSTTTKNQPPITQSVPDMRPRSLSTSAAPTGTTNVPNFTFVDTEMPSTDGIDSRQPSHQSEQEDLFRAARVRMKLQRNAFKVQSVYAPLAPNTVLEGDLLWQPERIRVMWERRDIYGVLGLPREATTQQIKRQYRKLALKLHPDKAPDASSASTGETTSMDERVAAFVAVTQAYKILSGDINAINPNFWKSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDZ7</accession>
    <name>A0A8K1CDZ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDZ7"/>
    <dbReference type="OrthoDB" id="119163at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035476641" description="Chitin-binding type-4 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="25369" checksum="47FF9FD40D68A08E" modified="2022-08-03" version="1">MVRTVFAAALALALPAAVQAHGFMSDPMPVFADPYNKNMQSGLQTAGATPGPYAGSDVIKDLAEKAGSKCGKTDANAPAVAAPADGVVKFDISAVHIGPCEIWIDNEKVVSAKDCWKEYPDKKIKVDFSKCKKDKCQLRWVWMATHTTPWEFFDNCANIKGSGSGGAPAPAPGPAPAPAPAPAPAPGPAPAPAPAPAPAPAPAPAPQPQVAGAGGYKYCGAARPDAAALTAWCNTNCPSFCPGDMCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CES6</accession>
    <name>A0A8K1CES6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_009480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CES6"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF53">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 WD40 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="160"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="387"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="474"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="601"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="643"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW61987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="73835" checksum="A9FA51C944343EB6" modified="2022-08-03" version="1">MHRGSKGVDPDLFAPSAGGYGANGGYSKGSSGRDPSAYASFADTGVDYGHSATNQTIPLATIELEHMSGFTGKGRNTLHAHPMDADGYIACMGAAVVIGNIRESHNQELLRGHDEEINVMSVSNSGGLLASAQIASRRRQEHGATIIVWELANRREIYRLPGFQRSVIQMAFSPDDHFLVASSEDCRVMLWDARTSELVLTKSFPTPITILNWGKSEEKARRPKYTLTMAYSSQLLTGELAYDIGCMQYRLEVAPFAMPNVGLARSYLCASMTPSKTDLLAGTIAGELVIFNTEAQTYRNALPVSRNGVHSVVACRATGFLYVGAGDGVLKKLVGREAEWNLVGQVQLVGGITSISVSPDGSQVFAGTSAGKMYHIVSTTLVPTELASSHLGSVAGCGYNEASSEEFATISMDGSLRVWNLSTYRLKCMATEAVAGLCLAFTKKQNPPLIVSGWADGWVRAFDASSAQKKWHIANAHRSEVTTVATSFNYVVSGSTDGAVNIWSTQTRELVLQFHEHKRAVTQVLVDIGKPHWVHSCGLDKSLFIYDLKNERRIMAQHSHDATFQGITQRLDSETEIITAGSDGRMLVWDCDIADPVQYLVDPNHLRVCAVNISPSGRYLAACGDDCEVKIYDLRTMSVVSAALGHSDTVNSVAWSPDERQLVSVGSDSCVCVWNFYTDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF38</accession>
    <name>A0A8K1CF38_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF38"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="495" mass="53982" checksum="0032B77EBF6DDA11" modified="2022-08-03" version="1">MLTSDRTLDERGVILLLCYINFLNYLDRGIIPGAPESFQHFMTETLGITGAEQSWYLGLLTSAFIASTATCSLIFGVLAIKYRPFFLIAIGMASWIFAVFICGLAHSFKNYYLLLFGRFLSGVGEASFHCNAMPFINRHAPKENSTVWLGIFIASISVGMSAGYVYGAVMASSSMTWAGAFYIEALLMAPPVLVFLYYIPDDLNQVPRDKTSELPKALLDSSKSKTESPAKEAESDTEEPLLTQSYAVLAHPTFMLVALGHAAYTFSLSAFSIFCPVILIGMGMFTSEREVSFVFGAVMAIGGTIGTVVGGVVLDQRAENNTVPPPERARLAIELCFYLMIATVLVAMIMLAFMDYKVLFLVMLAATFFFIAAIGPAESVAVMELFPESHQAIAVAANTVLILVLGDVPSPLIIGWLKDTWAPRCGTVEIEGKAQLDPSCYKDRSGINGVLLFAVLWMLWAVLLWGAGKYLAKKDVQRPKATTIVAETRSPVQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFG2</accession>
    <name>A0A8K1CFG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_009840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFG2"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_uL2_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007180">
        <property type="entry name" value="PRK09612.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="9">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="8">
        <location>
            <begin position="96"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW62347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="27946" checksum="D344D92AD0603AAE" modified="2022-08-03" version="1">MGRVIRGQRKGAGSIFRSHNKHRKGAAAFRALDYVERHGYIKGVVKEIIHDSGRGAPLARVTYRDPYRYKLKHELLVAAEGMYTGQFIYSGKKATLTVGNILPLSVLPEGTIVCNVEARIGDRGVFARASGDYAVIVSHDEDKGKTKLRLPSGSKKTVPSACRGMIGVVAGGGRTDKPILKAGRAFHKYKAKRNEWPRVRGVAMNPVEHPHGGGNHQHIGHPSTVRRDAPAGKKVGLIAARRTGRLRGIKKVEKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CFY8</accession>
    <name>A0A8K1CFY8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CFY8"/>
    <dbReference type="OrthoDB" id="20799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057494">
        <property type="entry name" value="Rossman_Mical"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25413">
        <property type="entry name" value="Rossman_Mical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="2">
        <location>
            <begin position="721"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="[F-actin]-monooxygenase MICAL1-3-like Rossman" evidence="3">
        <location>
            <begin position="876"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW62485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122997" checksum="A582BA71E9A7750C" modified="2022-08-03" version="1">MGPFPNANVRAHPPLLSVLLMADVVVDNQQEPQRELSPAVKTDKGDVSEDNQTTHDKVVRFEEVTSDKHDNNDDEHEHETRPSEIRASDVDRRLTWIGEGLLDGEGLEAVQQFASLPSDDEVSTPKSAVSTDNDGVVTKERSMSSGSKLTDFLAKEDSFKGLSPPEAPRRPSPPKITKRESKLLDFLAVDVGERYLDDVYQDEDRDEPTEESSATPTSTPDQSPATKKNNKLLAFLARERGERFHEVEKPGVGPVAASGTSTPPQASSPPKSTQSTPAESKSRSKLLDFVGKAAENRPKFVIFNPDDLVSSSSSGSEGERSPTNRNELRLKNGSRQQVHGNHAGHDDHAGVYRQPVLDRYGREELLDFGPSSDVTTSQAPAEPEEAKPRRAPSPIPTPPQPVSTPAPKSDGRIAAFLRKFSSNSSPTRDPPAPRAQKFDTPPRMAARHSSPPTSSPAPKPTTRFERVMIEDRSSATSAPSSDDGSVSVPPAERSAESPSSLISLDSNSRRMSLIANMRQIVEDCEKNELSEISVVRISTLLASINQIVREDLRKERPAQRIYRRLSGNSPTPTNTTRPGRTASWVRSEQEQAEYEKGHVTTIADIADYVDKSDSEMDKVNNLVKAPKLHPIDGVVVAEGVMASLTAFEIGQNMDEILVAHRRLLKDCGMETAELHAPLKVYQQVKSCVYDQLSFRQKQLFRLLDTKLSMDAYHKQPCKGKRVCVVGAGPIGLRAAVELALLGAEVVVVDKRHAFSRENILHLWPWVVQDLTSLGAKVFFPQFCHSTAYFHVGTRQLQCILLKVALLLGVTMYQKTSFEGLAAPESIVSERRPFYTVVTKPQIPWMEFTAVLSACGTKDKLSTQAGIKRFVFSRKEAIGLVCYFPNQGTTEEKRVKEFSWTLQFKQQMFAKMRDIGIDLENVVYYRGEYHYLVMTPKRQNLIEQGVLKVNYPVVSDLVGVDNIDPSALNDYVSRVINFFEVPQKSEFARVRLFDFSARTRADKAANILSSRGKKLYVGLVGDALMEPFWPEGLGTCRGFLSAMDGCWMVSQIGKESDEQILADRELGYRIVQHISGFRREDLQKNVRRYSVDPSSRYTVRFPAPLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGB7</accession>
    <name>A0A8K1CGB7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_005445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGB7"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW62827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="22173" checksum="CB0332B1A7AD5BFA" modified="2022-08-03" version="1">MKRDEAIAYFQHKVEENPMDPDPHHNLAVLYRSMGDQENHARHARIAVLTKEGGPKVWNEMALSLMEQGKYEEAKEKFAQVIQFWPTFPWAHVNMSVLLARRGECSEALACCLKAVQLAPQDASVHRNVAKVYEALGKTSDALEHYHRALSLVPDDADVAQRIALLSLSKQRTADATVHYDLYRRLTGQHFDVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGH3</accession>
    <name>A0A8K1CGH3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGH3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="149" mass="16707" checksum="18870E0363BE7B21" modified="2022-08-03" version="1">MVKYIKLKDSDLDPETIHKIVEDVFARPVVYLTQYKNLANDELLLKEAELIAAAAIRGNTLQFLARAMATSGLSLLKSPFDTISRARGSMLMYRNLSHCRQELIRRGLQPQFPLKVSVSAGNAIIILSCTILRELPVPMLKKLIPDEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGH5</accession>
    <name>A0A8K1CGH5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the endosulfine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGH5"/>
    <dbReference type="OrthoDB" id="5949865at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358">
        <property type="entry name" value="ENDOSULFINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358:SF6">
        <property type="entry name" value="ENDOSULFINE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="511" mass="55953" checksum="C021961BFE4BFC4C" modified="2022-08-03" version="1">MEERKHKYNFRPTATTAMTSGGRSQWHGMDLHSTATSTPNRRAMYAMMATQSPQNRSLPKQQPPQQPTGEDTSLSARNILIHRKLRERKLYDSADEAMKKVMMAMDHVPSASSATASPAPVAAETVNSPRQTVTPAHAKMGASVFVSALSADTAAANRNPVESKPRAMTPVAPSASGGRYGPLGASPSANAALSARSILIQKKLREKKHFDSADYQLARYHKEGGTDSQDSGSRSPTEDETDLSSAGSSPMDVDMDPTRLNSPAVSAGSSRNKYEFGQMSPSMTARPSTDRYAGLSAANEILRRKFAEKKRGDGDYRIEQPSDRFRSSQTPAQQSPRFFPQQQSAAPTSGYPNSPMASSSPVFQSHPPALQSPGTKYGKLCAANVLIRKKLKERKRFDSADYCMERAKQGERNENSDDMDLEASAIATEKARVESQAMNHPVAKHIKLSTEARPWASPKAAAYGSLQQRLPREGEMASHESRLMARNLVIQRRLAERKRFDSADFYAAKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGI7</accession>
    <name>A0A8K1CGI7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THO complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_002052</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGI7"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000746">
        <property type="entry name" value="THO Complex (Transcription factor/nuclear export) subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25174">
        <property type="entry name" value="Beta-prop_THOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="201"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36727" checksum="80E4F0FBAA0F172B" modified="2022-08-03" version="1">METTGEGAALVAYTQLREIYGHSRKVYALEFNCNGSLLASGSNDKTIRVWPTTPFYEGQEKEQPSELRGHIDSIHSLAWDPTNPHRLASTGADKTVRIWDAKTAKISGSISLQSEALNIVYSHDGKYIAVSNLDCVILIDARKNRVVRRVVNPYEVNEVQFSKSGYLFVAAGHPAGYGTFEIMKIVPDKKGNPNLENVHKAVAHAGSCFCLDFHPSGRYVAVGGVDSLVSLWDLEELYCVRTFVVTTSSIRTVRFNYDGSLLAIGMEDTTLVIVNTETGETALTLQLQNVLQYLCWHPTKNILAYVGDKPASQKNDGRDGVIKWIEIKEPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CH19</accession>
    <name>A0A8K1CH19_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_002173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CH19"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="560"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW63232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="583" mass="63231" checksum="497712B052C91F15" modified="2022-08-03" version="1">MILAETCLDPPDADPACTLARYNQKECSVVCKTKRVQKSVWEVEETTPNPMLEQLQGHLQLLGRFVSDTKAAVGLILLVGGAGAMVLGVLWLVILQFFAGCMIWLTCMLVVLILVLMSLFCSVRSGIINSEALEGLAFLNGMNTSGAIDLNSNALQAIDNASDRLQFKAAAYVLWVLTGIFLLLLLAMRKRIHIAIAIIRESSRAIKTLPLLLLWPVVPTIAFVLLVMYAVTIAAYIMSSADISSVLESTAALATASTGSTSSSVAAINGTLSEIPSDKIQQVLLVYHLFGFLWTNQFFHAISICTIAGSVAQYYWTPPDGNNRRKLEARFPIARALRNVFRFSLGSLCFGSFIIALVQLLRILLEYVDHQTKELQQGNRFVKVAFLPVRCCLWCFEKCLKFLSKNAYIFIAMRGNSFCSASVASFKLLFKNIARVAVVNSISFFLLLLVKTTITLTVAGVVFVALSNASASSQLKVLGAEPVTSPMAPVLVASILSWLIASAFMNIYDAAIDTILLCFCEDTELHGEGSSEFMSPELRRIMGDTGSKPKVVHVGLATSVTKSGSGGGGEPGGNKVHVDNDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHS9</accession>
    <name>A0A8K1CHS9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHS9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW62723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="60282" checksum="A7C30DA9C76EFC99" modified="2022-08-03" version="1">MVLQTLFEKGRVAAEELNGTHVVVGALLIPVTLMALQRAYTALTKKDDTVSVHKPLFRPSTTLPWLENTIDFAGRVARFHHWMVEVCTEGQGRPVQLRSLGQPPIVIVSTPELVEDVMKTQFDAFPKGEQQCELVGGIVGDGIFAADGVKWARQRKTASHLFTARTLRESMTATMRKHTAVLLRILQCSQQTGQSIDLFNLLNRFTIEAFSEIGFGIQMNCVEAEEEHPFQSAFDGAQRTIVLRFMVPPWFWKAQRFLGVGSEGQFKKDLKVIDDTVLGIIAQSIERRQRNGNVSSSVDLVSLFLDHFDKSSENEGEEVDVRYLRDVIVSFLIAGRDTTAQAISWFFLSIHREPLVAHKIRREIQTMLPELYNGKVETPTMEQVQQLTYLEATLKETLRLYPSVPCLPKSADRDVVLCDGSFIKKGSRVAIPAYAMGRMPYIWGPDAEEFKPERWIDPETGKIIPVSPFKFFSFNAGPRMCLGMNLALLEMKIVAASVLSRFEISVLNDKEVTYDFSMTLPVLGAMRVDVDNVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHY4</accession>
    <name>A0A8K1CHY4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_002335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHY4"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW63394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="751" mass="78509" checksum="DCFA8492949BCE37" modified="2022-08-03" version="1">MATATEAYAFIVAASVFGMLFAAYLFWEVSKIKVTRRGDGYALLSADVRGQTADRLFEIYSAIQEGARAFLLAEYTLCFAFIIIFGAFIVVLTSYVNKPEQTFDWTVGALTATAFAVGGLTSMAAGYLGMMVAVYSNARTTVSAMKEGARGWVESFNTAFRAGAVMGFGLTSLALLVLFILIKAFETQYPLSTNSKQLFEAIAGYGLGGSSIAMFGRVGGGIYTKAADVGADLAGKVVENIPEDDPRNPATIADNVGDNVGDVAGMGSDLFGSLAEATCATLVISTQSAEIIAAGWPAVLFPLVITATGIFVSAACTFLATHVWPVKQEKDVETVLKVQIFSSTALMTVLIIPVALWLLPAEFVINGVYHVTPIKSVYCVAVGLWGGCVVGFVTEYFTSHSYTPVREVAQSCETGAATNIIYGLALGYKSAIIPITVISIAVYVGFSTAGMYGVALAALGFLGTLCTSLAIDVYGPICDNAGGIAEMSELPAEVRDKTDALDAAGNTTAAIGKGFAIGSAALVSLALFGGFVTRIEETSINILSPITFAGLFMGAMLPYWFTAMTMKSVGVAAMEMVKEVKHQFATIPGLLEGLPGHGPPNHAKCIKISTDASLREMIPPGLLVMLSPIVAGTFFGVHAVSGLLVGALTSGVQLAISQSNTGGAWDNAKKYVEKGCVSIEDKEGKLIVQGKGSAIHKAAVVGDTVGDPLKDTSGPALNILMKLMAIISLVFGDFFKSINGGRGLLNVPLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ50</accession>
    <name>A0A8K1CJ50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ50"/>
    <dbReference type="OrthoDB" id="4447at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="633"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW64566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="728" mass="83766" checksum="25A28DA75E64B800" modified="2022-08-03" version="1">MAKKKTGGGKNKAEKELTKAQRIEAKKAKQAAKGAKKDRKGVDEEDIELILQEILKKDAQRKEVIVEATTQPSPRANFSMTMLPTGDMMMFGGEYFDGDTNVCYNELYRWNVDGGPTDWKMISSPNTPPPRCSHQAAVFRDHLYIFGGEFATADQFHHYRDFWRLDLKTNSWEALEDKGGPSPRSGHRMVVWRNYLVVFGGFYEAARETKWYNDLFLFSFAEMKWHKVTYPPLKAVPGARSGFQLAVHPSKDQIFLYGGYAKVKNVGEKSEGKVFSDLWALNMAPVLKRQEPTWEKLSRKGQAPSPRGGTSVTVHKQRFILFGGVYDDEQRGHAMKSTFYNDLFVYDMDRRRWFEFKLRGKKQADGKRRRKKKDRGEQNGEADNDNDDASDGSDEEDEDDFERMLENQFGYIDQDGNFVYIKDDEEEEKNDEAGGEEEETKEEEEDDSSLLATQRAVLNDEEEEKKEEEEDDSALLPPPAPVAAEPVAPSPCPRINPALIIRGSTLYVYGGMVEDGDREITLDDCWALDLKRLEEWKELLPGTMSEQVWKGEVSETEESSEGDDDDDEDDDDEDYEDEEAAVVVQRAVKMLKENDSDEEESGKKEKKKKSKSKKTNDRRAIRAEIEKLQEQLGLDDINRTPQMGENLRDFFARTQEYWATVIGQRPDTIERQLNIKEIKREGFVMAEERYNELLPILERLNVLEAEQKEMEEQYLLKKKGGKEKARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ74</accession>
    <name>A0A8K1CJ74_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_014156</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ74"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001840">
        <property type="entry name" value="Paternally-expressed gene 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="250"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="470" mass="51547" checksum="88D88212B1CFCF7B" modified="2022-08-03" version="1">MLSSGWDPEADLRPILLKDLQGDNTAPKTATIFVCTYPGCGKQFQLKGNLKRHQNIHRGDKQFKCDVCGREFLRKADMEVHQRVHTGEKPYLCKFEDCDKRFARRSDLLSHERTHSGKKPFLCDYPECGRRFARRFDLHKHQRMHDGDCEEGATKANKKRPLAQTTATSSAAVPTAIPSHYSKVGQFMTQLSSDRAPTPRSPARQAPISPSDHMEGPGKDRQFELTCTLDHEHFADCFTAESWDAMMEEAGMSSSSSTESCCTSHLPNGKTKRESPSKSPSIKAETKHSFVSQLLAKTSPPTVMSPKTSVPTASTSAPLPASTACPIVATAKLHDYAAHTSCGHLAIQHGDHRDFVVKNHLVCLDNVKSLSGNCSSGACVPISGTKSTSTAPAATTVTTTAPPTDRQPRHPHRPGCGHLPVRHGDHIDYVVDDGLFCQQAGFLDDADHIELLGDDFWEFYGAIGSLNTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJQ4</accession>
    <name>A0A8K1CJQ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynein assembly factor 1, axonemal homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009048</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW64881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJQ4"/>
    <dbReference type="OrthoDB" id="1904536at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF9">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW64881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="54052" checksum="DB642229C1109DF2" modified="2022-08-03" version="1">MVEMEKAFLKKLCRDHDLYVTPSINDKLYLHYKGFRCIKNLEEYTGLKVLWLEGNGLPRIEGLTHQTQLKTLYLQENLIQKIENLDAQLDLDTLNLSQNQISRIENLSHMSQLTSLTLKSNYLVSADDLAHVLTLPKLAVLDIQSNRINDPKILEILAEMPSLKVLYLQGNDVVKHIKQYRKTMIYRCRKLKYLDDRPVFDEERRRVEAWGQALEAANGDYKAAQEAEREEMDRIRQEKRDRDHQNFLMFEEMMAEGRRKRQEDEADKAKREKQEETPEINPFSGEKIVPIQDYEFLQRQREQRWEQVVNAPDAWGGKTQEPSNQEATENEGDASASSTGIPVDAQRLEILHQCATVGVGTVSGRDAFVESAFQVSIDPGEEAKKAHRERIQEKAKAKVQALQAQKQQQVVLPPATCLINTVTASDLLDKVDVAMLHPMPAEQVLMPPPAPARMPLKTQTTPPIHTNVDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKL6</accession>
    <name>A0A8K1CKL6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKL6"/>
    <dbReference type="OrthoDB" id="79864at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="636" mass="71049" checksum="8EFB6EC66C119BCE" modified="2022-08-03" version="1">MRALTEFALREALALLLDDPTPHNVALAATGEAPEASQSMESQTDEMSEDSESQAARQEMLAARETQPRVVMVRYTNASTKMITLVDRSHSVDAFVPDGVMTALKDKYGYQTLSRLRGSVLRVEKYHFSTPALCYREEKIRDPQETKSAATPRMDRAKICLFVEQLSVVDDNELAVNPLPHLEEHEAIANIVSKLSESELEQRIMLRQGRALPAATDNDEIHPLLEEDVAIPEEEERAMNAQEGWDDDDEEGDGLSDSQLIEENGPVSDSLPEIPEPSTRRGSLSQRMSQLWNAVRWVVVPTTEEPEATEEVPESQDAYHFQQDNIEQAFVEYEDTESEGESDDEEEPSSKTADKEGESEAGEEEEHREIDTQTTETQLDVMYETENGPLTQAPDETSQSETPPQPRDLPVGKPNTQLSPEDGTEDSQARVDASQLHTSVSQPNDSQYELGEAADQHWHTQADDDSQMMIPQPQSIAQDELAETEDESAADEDVADDDHGEVELHVGGQNDDERSDKSAANVPASARAESNRSEESLRDQSDAERASFRQKRKRALVPEIIQKRQRQDQDVESPELSQRSGKRARSSGASSNATFGLSSWKKKPANVQQQRPAKQYQHLLPPFRLDSIMSMIANKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL90</accession>
    <name>A0A8K1CL90_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_008231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL90"/>
    <dbReference type="OrthoDB" id="155724at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38130" checksum="C9A0590488280746" modified="2022-08-03" version="1">MILEMGLGIELDWIGAETKHPVEHAADLAPNLIIRRTRLPRLVWKIQRWLNIGSERELRHSMDVVLNWVRDIIQESLENLARKKEEGKDHVRTGDDGEEIKSVIEIYVENSRDDVLGLRSEDLVDFIQTFVLAARDTTAVTLSWLFFLLRDHPQVEKKLREEITTKLPQFVGDKNAYITTEHVRLLSYLEATIRETIRLYPAAPSTRKMAARDTVIGGDIFVPKGMNISLMSYAMARSTGIWGPDAAEFKPERWLDVATGEVTPVSTNKWFSFHSGPRVCIGMNLALMELRVVAANLLLRYHFEVDPAHPGKYGLALALPMKDPLMVKVLPTQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLP0</accession>
    <name>A0A8K1CLP0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_009405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLP0"/>
    <dbReference type="OrthoDB" id="148820at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="372" mass="41232" checksum="C8854905D4946A0B" modified="2022-08-03" version="1">MSPASGSSSGSGSGSRGGAVGDDDAWYLVGDRDRNSTGDTCGYYQLESGQSCRKPRRCYDCLNAEVEGEPDGCVLTPTGACKRMDAYVPNRDFRADNVSYTNYYPSINTTYCESTDPACDRCRKIAAEAMQSSVAFEGSLEMANKSDETVRRFCRGIEGCVCVAVCESPQWRYSVQEDCSTGNDTYDISSDDNYKSALPIFMALQVLLIIMVVYRQGAYARRYRRRRAAEGPYNANAISSPRNRLQLTGWRAMHENMINREKAQHGLVSLMSPRTGDEPLEQNVIMTDDEIPELPEHYALETPMNRPRRASTDMAILEDGRPSDLSRRPTHVDDEHAGEENSHASTEPVATTSASAEAKPPAEQEEQQQTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CM42</accession>
    <name>A0A8K1CM42_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">ribonuclease H</fullName>
            <ecNumber evidence="4 10">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_008226</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 10"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CM42"/>
    <dbReference type="OrthoDB" id="407198at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000275">
        <property type="entry name" value="Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000001">
        <property type="entry name" value="Ribonuclease H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="12">
        <location>
            <begin position="196"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="56"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="363" mass="39969" checksum="7863B71A4006E810" modified="2022-08-03" version="1">MGKSAGGYYAVAVGRSTGVFMTWSQAEAQVKGFPGAKFKKFPTQNEADTFVRVNGGSDVKLNNQRSPVSLLGKRSQPETVVGDEEGCKPNAKRHAPEAFSNECGVTSNPSSPSSDNQDTKSEMDGKAPRQPKQPAFYAVAKGRRTGVFESWAEAKTQVENLFSAKFKKFATREEAEAFVKEHQDTMQNSSDPDPKRPDTLVAFCDGSALQNGRFGCQAGYACIFPHNPSWNVAKKLVEKKATNNRAEYLAGLEAMKRANAEDPSGTQPLYIFSDSMLLIRSMTEWVAGWQKKNWVKADGNPVLNRDLLELLIKERGNRRVIWRHVKAHTGRSDWQSKWNDVADNAARNAAAGWEPNTASVSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMH3</accession>
    <name>A0A8K1CMH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_009234</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMH3"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="13"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW65067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="422" mass="46608" checksum="861B0E5030273B22" modified="2022-08-03" version="1">MKTLEFGQGENAHVAIITGAARGLGKAWAIALAARGVRVVANDNDQDHSLVDKVVDVIKSRGGIAVADYHCATEGAKLVDAVVKRFGRVDILINNATVIRDGSFRKIMLENWDAVYRSSVLGTFAVTQAVWPLMRKQKYGRIINCTSGAGLYGNFGQVNYATMKMALVGFTTALNREGVKYNIQVNAVSPVAGTRLTQPVMPKDVHDALKPELTSPILVYLCHPSCQEAGSLFELGGGWVGKLRLQRTHGVGFPTDVTSFTPELVAEHWKDIVDFSRVTHPSTTQESFEPMMRNITSPPTSLVTSRSQECSEVFNRLRSTLESEGPALAKQISGVTEWHISNETWTVWLLNGKGSVIEGKDSRYTPDLYIDMDEESFMELATGRLRIQQALIRKKLRIHGNMKLAMKLQPFADLLQRPHAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMN6</accession>
    <name>A0A8K1CMN6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_008047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMN6"/>
    <dbReference type="OrthoDB" id="63806at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33946:SF4">
        <property type="entry name" value="COAGULATION FACTOR XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035456228" description="Apple domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="123"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="278"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="4">
        <location>
            <begin position="504"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW65405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="571" mass="59565" checksum="80E97934B73CD9D6" modified="2022-08-03" version="1">MLVLLPVFLSAGMLASVQANSLRSIADVERRLARMEYMAAMTGHTNCYIENGFDYVGNDISNVAGQPVGNCCNLCAGVSGCNAFSWTSQNGGTCWLKSKRGEITVNPNVKSAIVVFSNDNPVCTLKNDVDFAGNDIGNKPASKAEDCCDICHNTAGCRAYTWTNQNGGTCYLKSKNGGESSKAGARSAEAYPVNSNPPPTCTLEQDVDYIDNDIGNKPSANAGGCCDICRNTQGCVAFTWSTQSGGTCYLKRAKGSTVQKAGVVSSLVLANPPPVTTCTLENNVDYIGNDIGNKPSADAGGCCDICRGTQNCVAFSWSNQNGGTCYLKNAKTQTASKSGVISSTIAANPQQPTCTLENGIDYIDNDIGNKPSADAGGCCDICRGTQNCVAFSWSAGTCYLKRAKGSTVQKAGVVSSLVLANPPPVTTCTLENNVDYIGNDIGNKPSADAGGCCDICRGTQNCVAFSWSNQNGGTCYLKNAKTQTASKSGVISSTIAANPPAPTCTLENYVDYVGNDIGSALSKDPAQCCAICKSTSGCKAFSWSNYQDGTCWLKNNKTTTKASAGVKSGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP05</accession>
    <name>A0A8K1CP05_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP05"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="228" mass="25698" checksum="57A54C34442A0354" modified="2022-08-03" version="1">MTTKNTADMARATANTAECDLMALLFPLVVASQLSNADLEKVTAVVRTLSDTLAATAKHVDQLKIWLHEAEAAEHTARQHLSRLEGEADDQEAVIRRLNEHISKCHAVVARLEDEAKRRERVIHWLEVDICMRDESLRWLDDHASRLYTFGRDMTEAKDVMEQDLETQCGCVDRLVEDVAQRDQEIEDLKKQVEMLTAALAEASSMPRSEETAPPPPKATRDSEDPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP43</accession>
    <name>A0A8K1CP43_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP43"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="46081" checksum="8F40EFBDD0A434E2" modified="2022-08-03" version="1">MPSTTIATSDHPVFKRFSRQQLVTRRRNIGYQTLVLQPTFPRAKRCKHCGRQFDSVWKEFQCHVCGLWVCQPCSYVLERERELQCITFMRSCVGCQPMLNKWLDPDLLAQFASSSWVVSCSKRQLSLNLSDILRMKECRRPALTVLKYLGRPVDPASPCVDTITEDEWVAATSEGSVGSPRHGSIVSNNAEETVVERVQHLVQQCFEVVIPEEPISDCLFAESNGSRLYPIHYDDPDEPPDAPVISSELERQAAIARYGLLTRSLNTPEIQLICNLAAQELECWAAFISIVSGDTQQFVASSPGTPCGEPNKRSQTFCSYALTSPLPYMIRDASLDIRFRNFDVVRGPANLVFYVGFPIVDESNNTMALLCVLDKKPRKNITTMQYSVAKRLAAVVSALWKELLVGMVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CPF8</accession>
    <name>A0A8K1CPF8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CPF8"/>
    <dbReference type="OrthoDB" id="204730at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030837">
        <property type="term" value="P:negative regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043587">
        <property type="entry name" value="Phosphatase_SSH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45864:SF8">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_164, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45864">
        <property type="entry name" value="SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="197" mass="21730" checksum="AF2B1F998E7C9E9B" modified="2022-08-03" version="1">MAPSPTKAVYVKSTVAVANGVEETNPEERTVVAGAQYRIRSTSTSSPSTRSFASRSLRLPAHLFVTVRRLFHPPTTAVPRLKPTFVLTSLLLGNEHNAANYDELYSLGVTHICNLDFNARNYFEGKFVYIKLNLVDRAEEDVVKHFDGVSQFLEACDAVGGRVLVHCCSGSALSPAFVIAYLMRKRKQTFGSTKLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ54</accession>
    <name>A0A8K1CQ54_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000007">
        <property type="protein sequence ID" value="TMW66671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ54"/>
    <dbReference type="OrthoDB" id="67124at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855:SF1">
        <property type="entry name" value="CLAVAMINATE SYNTHASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40855">
        <property type="entry name" value="DIOX_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035470487" evidence="2">
        <location>
            <begin position="21"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="525" mass="55746" checksum="380E96ECA3BD7CFF" modified="2022-08-03" version="1">MVSVSTMLAGLALSAATAQANSLSALPTFDVPAFDYASIAQGENPARLLQALQTDGIIALKNIPNYANLRERYLRTAAECAGVTANADHDMFVSRKLFDDGTKRYTISTNAGRELSGSAMEVDTTCPGYRQLYEEFSQTLEHAVNTFGSTLDQTSFTASDGQRSISSRQLVSDAVRLDHFHAYEAVPSGPASAGVDGIQRQLEELSLPLHEDHGLFIAMSAPKFFDVGADRRLVERELSESASGLVIQTASGSRVRPVLKNDEVVIMMGTGASRWLQTSHSIPAVMHGMKMPEGSENGVRSLRAWFGKMTLLPAYQRMLLSNGVSFEAHSNATTRFLLANQEDDLKTVGCATGRRLMASEGKCTLRECKTKAGKSDPAEGCPVICNRKNHSPDDELNCTASCECTDSSSPAERCWMLCVANLPESECATAEQTCTGQKKTCKSSTSTSTGSNKGSMTGMTGMGSMHMDGSAHKDGSMAMTSGSSAKTDGSSVSTDKTPVPAPSSAVRVLVSSAAVVGSVLLAAFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ87</accession>
    <name>A0A8K1CQ87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ87"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="426" mass="46294" checksum="841EC9DE46D41959" modified="2022-08-03" version="1">MANKEFDVIVYGATGFTGALVARYLLQEPESLPDAPSAIKWAIAGRSTKKLQAVKDQLKLKVSSVDAAVIDAIPVVVADSNDEKQLVDMVLKTKVVLTVVGPYQLYGEALVKACAENGVHYCDLTGETLWVDRMMHKYDAAAKKSGAILINCCGFDSVPSDLTTLLLTDAVKTYKKSKTSKVSIYFTDLDTGLSGGTLASAFANFDNSTSAELTRMGDPFHLIDEKNHEEKKVAGLIQANKSSLGISYEADLGRWSSFFFGGDVNAAVVHRSNFLKKSAYGDKFVYRERLAAGGLFKQIVMTISVLVFNFLLYFSVTRNVVRRLVPKPGEGPSEEVMQNGKLVAKGVAYNDTGDLVARSTTIGTGDPFYSMTSKVIAETAMCLAKDEIANVDVKKGGFFTPAYSVGAHLAKRLHEKRIMTIDIRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CR26</accession>
    <name>A0A8K1CR26_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CR26"/>
    <dbReference type="OrthoDB" id="58083at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0410">Iron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW67175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="161" mass="18204" checksum="DF45C8065030B944" modified="2022-08-03" version="1">MWKRCVRVASRALAPATTMRALPSAHVLVVRHKFTVPDSAVAARRRRLKPKLANDKFVSLASAFLDRVEVAVTPLQPPMNEDFALDRSTQDVVLIKAGEKEFELKVISAKQQLHLTSPISGLRKYEWNQKTQRWEDESDAHDLEGLLTRDLMRLCSGVPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRN5</accession>
    <name>A0A8K1CRN5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRN5"/>
    <dbReference type="OrthoDB" id="124020at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="595" mass="67312" checksum="5C3385614C787706" modified="2022-08-03" version="1">MIDFQGVQCDLPKLEWCFSFLTALTTRVLASELQAHFTTDSNRQTPRWIAVGLDLSHCELTTSQFVKLHEVMRAYAEFEPPQAESSGCQQVFFVITSLNLSWNEFQSHRDYEIVTDIMLLQSSRVAVRHLNLTNTFYAKTPIAHVTAFQWFIQRVLRDDASSLEELSLGGECHVSDAHVAAVYSALRYSTKLKALRIKQNPESTSKEDVSCNFQAMWSWLALAVMHSSSVSTLMSLAFPYFAITEEVVDCFQKTLESEQPAMIALTAESPEMEAIVKRDSEARIHPAGKTFVSIKRGSKLRLWPKTQASVLMLSQYAIDRPLEVVLTLSKWTCVIIPGCGFGWVMNAALVVHEERQMSSRRIPLRAFMWIAPKTYTVAHIPAVRSLVCLIGEGLKALYLAKTQFTTDDMATIVAHCPLLQHLEVPRHNLLSLEFLRKHSSIRLRTLNVQFFVNGPAIDAYSPWSLVADLVAFLKSPASQRLWHLAFEYKWDGMMVTRLLTAVEKHPTLETVDIFHVSNENGDVYERQATSPGQSPAMRQAVKLAFLSVIRHQLETTSIALHRLDAVLVAAIFLFAAEPTQKQINHIHRRAYTRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSM0</accession>
    <name>A0A8K1CSM0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSM0"/>
    <dbReference type="OrthoDB" id="167763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="337" mass="40237" checksum="39B5E3F2F21D258E" modified="2022-08-03" version="1">MPRSATKDAEDEELRWRCAREVASLREQLVESDEEKELLRERIMVLTKHLTDTTEELEQRMALFAEATSQIEQLESQVSDAKKAVLSREMQIHELKQKSLGLEKVMETKDKEREHWEREYIAAKDEVARMTRVTQRMQCDHDEKTGEIATWKAKLHKMVKAFEELKRNQEEMRRRELVLVDEITRSKASLMENEKKWKLRLAKRERMIATLEKEVEALRKLKADNEDEKKKRVDEEAALRTNEATSQLEKRRQLLTLRADLNRAKDDLQKSKLAEMLLQREVRRLREELLLSESQRKTDHRRSEQLIQGKEKEMAFVWQKYVEAKCPQPVNKPKDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTF6</accession>
    <name>A0A8K1CTF6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_006081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTF6"/>
    <dbReference type="OrthoDB" id="10266364at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019148">
        <property type="term" value="F:D-cysteine desulfhydrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000037">
        <property type="entry name" value="Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005966">
        <property type="entry name" value="D-Cys_desShydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01275">
        <property type="entry name" value="ACC_deam_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780:SF2">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="6">
        <location>
            <begin position="25"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="370" mass="41127" checksum="6CC0F63C18EB74FA" modified="2022-08-03" version="1">MLKSVPYVAPKWATALRSAPAKKLRLGHFPTPIFPFAPPGLPEGVKLYLKRDDFSGMETSGNKMRKLEFIFQDVVDQQADCIVTCGGLQSNHCRATAVVARWLGIDSYLLLRTNKPDEDPGLVGNVMFDRLINSTIIQMSRQEYGRYGSQNMIQKTCERLREEGRRPYAIPVGGSNGLGTWGYLSAIDEIQKQLEEEELKITDLAFACGSGGTAAGIGLGAYLQAQHSSQSVVRFDHANPVHAYIVCDNDEYFFNYIDEKILPEMGAASELSSRDFLQITNAQGTGYARSTVEELEFISEVARTTGVVMDPVYSGKALFHLVRELNENPEKFAGRSILIVHTGGQFGLYDKADQMQKVCDENPVQRFTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CUJ4</accession>
    <name>A0A8K1CUJ4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CUJ4"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040099">
        <property type="entry name" value="ZZEF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22772">
        <property type="entry name" value="NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22772:SF4">
        <property type="entry name" value="ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW68513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1153" mass="126519" checksum="AAF66420C30368EB" modified="2022-08-03" version="1">MNRAIRAVAAAILHHNMWSADAYAFAQNPQTDLSEHLVRGWNNAQKMRDWFHMGDATDVIRANQAPSTRSSSRSLRRQPSAFSGMTDEALETLYQNVIDRAQFLLELTPMTVSQVSDAKRRWSLLAKYGSALSAAATAPGTILQKWHNLVDEVQAVTELRSVLQYRRGASERAKEGRVMSVIEQVLAFVQSDVSVKELRVAIQQRNLRAESRALGLQLFAQSWDASTNVEVKGLLAESFYSTIKHMAATSSSSVSKHLEASETSFTLSARVHYGMMLSGCDSSRRIQVNDAFGACLRGFGHELRKLADANEANPDVIVSILKALCFDFDIQDAFLLEESKLMMQVAQFLGAKTCQVRRAAQTLLDIVLECFVSREAFRSSEVSKDGNGKVTTVVSPFQRQLYGILSQQLESVTAQLREVGSSREASAPEVLRLGGDRPGCSLSVPTFGRASHNHSISLWLRPDSVSPSCILKVNDVVKRGSTWKTEEDSDENLNETGSVIGIVSPTSIRVQWKETKRISEHKYDPTGGVMDVVHVDHNLGGVVFCKGTKALAKAPGNMEREVLATTENVGNLLFVAFHESVSIEARCASVILLQDLLVEVSMDVVEAELERVFGQRGFVGFVLDFIARLTNVWENDDVFVPGPSSSFGPRSSSRDAAALASAYVTLLHVLGHHPQWSNVLFDEVTAVLLHSQVLTTGESSKQWAEVTGKLLSVSALLGGLYDGIVTGGRVKRFIRVGNQDKEEAGYLLGIYREGSACKARVLFDSSPNDISSVLFSDLAPVGDGEDENLAGFWRCMAGFGNGLHQAIMAQLRLLEVVESTKPKSKTVRKENVQVLESHHPYSGGEEITQTLRFDGAEEILIEFDESSCSLGAGDSFSFKKRDDDNRSLSDEESSNGLDYWSLEKYDITSLPGVGENFPLRIPSESVDVRVCTGPAEEACWGYKLIAKAIAHTVVTPPDVAPSAILTAAADLRARLVKAVHRGIRILSDDTSISAFAPLVPALLKLAISPSLGQPTKVPSRSAEYESEHPYKNKLSETKTISFSGASRLIVTFDSRSRTETDCDVLTFYTDSSQTEYWGKKEYSGEGGSGTWPGLGGRDPLIISADSFTLYWKTDHSNVDWGWKFTVVAEYPPTSPGALQADELDKRSYDIWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CV63</accession>
    <name>A0A8K1CV63_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CV63"/>
    <dbReference type="OrthoDB" id="165703at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="195" mass="21972" checksum="296659B8372E862D" modified="2022-08-03" version="1">MRLLRFYPLLLCLNAAGGFALCQWFRSHDLRTRETTGDLSVKYLLTAAPQFLAALLLLFYACTFNRDGSEFAHRMLVESCLHQALTSLLMTAIVHSGFHMTHSGCCAFPSACPVDVHDCRFHAVFQCPQPVATSANFDFYPRLAQFIATCIITLSMMSITPVHVYKHLQSRVRHGELLTFSRHLPIRPASPTVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CW57</accession>
    <name>A0A8K1CW57_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mis18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_001872</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CW57"/>
    <dbReference type="OrthoDB" id="74210at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034752">
        <property type="entry name" value="Mis18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16431">
        <property type="entry name" value="NEUROGENIC PROTEIN MASTERMIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16431:SF1">
        <property type="entry name" value="NEUROGENIC PROTEIN MASTERMIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51793">
        <property type="entry name" value="MIS18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Mis18" evidence="12">
        <location>
            <begin position="133"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW69716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="312" mass="34275" checksum="F6333569981330F4" modified="2022-08-03" version="1">MARKRLADDDEFIPSDEAETTVHTPRVKKAKPQTPAKSAAGYGSHNGSATLKKTPVKSVKSTPMKRPGPTKTVTPARSRVNESNRIQHLSGYFAENDDDEESVDDAAAESEEVFDGEEDDDDEEDEDDEVTAPVVFQCGTCRSIFGDSYSFVSSNAELLLVTLNAVTNVAVAPEALTAKDGPDIGSAFQELLCKQCQTVLGRKYLTTPNNLDAIRGLYSFSTTCIASYQLGYPQLNQTNGENTMSSKAIAHANQECQSAINTLSMDRKELMKLRDDMTKVQNVLLVVDQRLHQLETQVEDSEAEEDDDVPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB22</accession>
    <name>A0A8K1FB22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_010548</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB22"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW55666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="320" mass="36417" checksum="7DC120C9BADBFEE8" modified="2022-08-03" version="1">MDPTALVRESTARVVAQATHVHIDTAAVIRLAEKLGTKLQNDEQGFVTWDSGDFHYFADVEQDGPLTCQYVFVMDALNFCFWPTEHMEYEHLARGLKNALLKDPQALDADNLINVSCATITSWFHPFVPPQLEERQRKVQEVGQVLKHCFDGLALNLIKQANYSAAEAVRLILAYFPGFRDHTVYKGEQLHFYKRAQILVGDVWAAYGRRTSGLVSFTDIHKLTMFADYRVPQVLRPEGVLVYSSELAAIVDTKQEIPSGSEMESEIRAATIQAVEQIHAQMRAQGHELKVIELDWFLWQIGEDNKDALQPHHRTLSVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FB64</accession>
    <name>A0A8K1FB64_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Orn/DAP/Arg decarboxylase 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FB64"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000025">
        <property type="entry name" value="Diaminopimelate decarboxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43727">
        <property type="entry name" value="DIAMINOPIMELATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43727:SF3">
        <property type="entry name" value="GROUP IV DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="5">
        <location>
            <begin position="109"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW56940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="514" mass="56128" checksum="041C680173C586BB" modified="2022-08-03" version="1">MERVEWTKYVALYDGANAPRVVQQLCDENALELATVGTVATTVLHVLHQQQKAQAYVAPASVQHSDAEERDAHEKRSRQASGVVSAVIAHGLLHDENPLVNLFDVDAYRARLENLHAAFPEKEFNHAVAIKSNPVRGILREAQRLGCGAECASYAEAKHSLSLGFAPRSVVYDSPCKTRGELKEMLLAGVFINLDNEQEIGKLQSIFAEIGEGHDYEAQIGMRINPVVGGGSIDATSTATVTSKFGLPWTDETSERLFGLYEANPWLQGVHVHVGSQGCPIDLLVAGAKRAVLFAVELNRRVGRQQIKVVDIGGGLPTVYDGGIEEAYDFKVYADAIRAQVPELFTSGFSTIITEFGRAIFVKPGITVSKVEAVKNWSGQNIAVIHAGADHFPRTAYLPHLWTHSVSVLDSQGRVKPASVPYVRQDIAGPLCFSGDFMAKQVLLPQIEVGDLVVIHDTGGYTFSTFSKYNSRQAASYYAHTGVDGASFKFSVLKERETAEETLAFWGLDRAIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBE9</accession>
    <name>A0A8K1FBE9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_003120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBE9"/>
    <dbReference type="OrthoDB" id="1436450at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="68"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="249"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW57195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="412" mass="45432" checksum="B9FBBE17F1CF5B4A" modified="2022-08-03" version="1">MEQGGSTTNADGCKKEEEAEEEETDMGVTSERTALVQSEAPAQQYQAKTAPLPSPKKKKEHSTFEWTLGVFFLLIVALIWTFASVLVQYIFHELSFQGPFFLTYVGISLFSVNLPLWYLSQVVWPRLKSWFRGDSWEGKDGKLSHAQLMRRSAGTAGFMAIFKISAIISPIWFVANFTYNQSLNMTSVTSSTIVSSTSTVFTFLLSVFALKEPFVWLKVFGVALCMLGNVTTVFNDSGVEDVGAEDHVFGDIVALFAAFMYGVYTTCIRRLIPDEESVSIALFFGFLGAINFVVLFPIVIAFHYTGIESLSGLTAEILLLIGIKGLFDNVLSDYLWARAVLLTSPTVATVGLSLTVPFAIFSDYIFHQAVPSLVTLLASSLVVSGFVLINVSTKNNKHDYHPEAPAVIHDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBM3</accession>
    <name>A0A8K1FBM3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_003360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RING-box family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBM3"/>
    <dbReference type="OrthoDB" id="100116at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031463">
        <property type="term" value="C:Cul3-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000273">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger RING-H2-type" evidence="12">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6604" evidence="13">
        <location>
            <begin position="123"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW57435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="466" mass="53426" checksum="77A5F20DC1D732F6" modified="2022-08-03" version="1">MDEEMKSAEVVPPPAPSAAASDEKRFEIKKWNAVALWSWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQTAYRHSRSIMVKITTPQTTFPGHIYGKYKRAMQFFVDWVLRARSPSSVNAVADSTSISIRKLHDAVTELASRPSSLRPQLRKELPLALAACEVAIRLREHVARFFSFEPSTTKSPSNESQAYFVDRLKAWHASLKSLQTTTTSKRGAVKEEPTIQFSNYYDVLAIPDDYFPEVETIELDQPEESRRLTRSGSSDQGKSHVPDNIKLKKAVKILEYFRNYAAMYTLSERQSAHTREHSLFVAEGSLRVIHIMDKHHQQMPEPVRVPRIKLCDTEPDLDPSKIPPLQYLEKRCETNSDWFRFALHSARVFISCNRTNQARELIDLAEKRLLKLKQRPLYFRIGFRLTLESEKKLVSVVCRLKARAKSNSNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBS8</accession>
    <name>A0A8K1FBS8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_013901</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBS8"/>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000149">
        <property type="entry name" value="Mitochondrial Carrier (MC) Family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="31"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="119"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="204"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW55139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31767" checksum="4D2295566FCC1553" modified="2022-08-03" version="1">MATTTSNSSMDQFAMRTIQLPATTTSRTQTPSVFQSLWIGATSGMSGMIAVYPVDVVKTRMQNSRVSTSALQVLRTTFRQEGIVSFYKGLGPQLLGTIPDKAISLATREYVKGRFEDPTTFVASFTSAATSGVTQSVVMNPVEIVKVRMQIDSSLNAVGVIRELGLRGVYRGYSACFARDVMFAATYFTLYDFTKKKLRIQDGSSIGWSMLAASSAGIPAAFFSTPLDVLKTRMQSRTATTKGFVETFKLVHSEGGVSALFAGWGPRISRIAPQFGIVLVSYDWLSAKFAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FC70</accession>
    <name>A0A8K1FC70_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FC70"/>
    <dbReference type="OrthoDB" id="149521at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="219" mass="25722" checksum="DEC35753A025C0C1" modified="2022-08-03" version="1">MGKPREFSRMLSISDGYWGFVHQKRFYRFAYATLTIFAIFALVAGFFKVGDGTRFASDYWKQKLHLTNAEMEENEQLLAWIYVFYPTPVAVAWFIVYFGKFFFCWRIKRLRKARNYKYNLLLATIVMAIGYSLIFWYFLKLDVIDGPKMRVALITAVCEFSLIGIEVFDQHQVRVARHRRKKLLVRQQEMEHEIRNQIRAGDGEPLGPQTGTQHPGGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE71</accession>
    <name>A0A8K1FE71_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006337</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE71"/>
    <dbReference type="OrthoDB" id="73639at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06463">
        <property type="entry name" value="p23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039742">
        <property type="entry name" value="Shq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048696">
        <property type="entry name" value="SHQ1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007009">
        <property type="entry name" value="Shq1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967:SF0">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04925">
        <property type="entry name" value="SHQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21413">
        <property type="entry name" value="SHQ1-like_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="532" mass="59839" checksum="C1CEBBE0ABED8E81" modified="2022-08-03" version="1">MPSIPRFHVTQDAAFVYVHVNVPYVRVSEMEFHVEGLHFSFYCKPYLLKLQFPHEVVDDDLAKAVYDPNVDNGTITVHLPKKDPGQHFEDLDLITKLLQPKKAPVVDLQAKSAPAPLIEVLDSQTTDTTDSATHEETEQAADGGDATLLELEKRFAEAAAAEEEELHHVKVSSDLSTYYGFNNAYKDVFRSWHGEASEIVSLPDPDVTPANRRRSLREEGEDMHFDVERYLLDYANADEDYYYEMAMTFEPFWRRYPVIKAPVAPPARAPLIVEVSSSTPEQLTQGISGLSLDSDASTSVLSDADRELLLRLPNKEFLISRGSKEEDVLLGGLADILAGFAYEQLTTQGDSGIESTWTISILSPTLAWLDSTDDVRAIVRSAVRRILAFPLLRQYKLAIHVLRETAELLRRGKRVVLKSLLELYRIVEKSETQYLLNSIYVQDYCIWIQSVDDQRLVHLADELSAAVNAFKKAETGWALEEMERRLEQDESEDEGDEESSSEESDSSDDDSESDSGAENDSSAAEPLRPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FE95</accession>
    <name>A0A8K1FE95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-adaptin appendage C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FE95"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000002">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1150:FF:000002">
        <property type="entry name" value="Beta-adaptin-like protein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013037">
        <property type="entry name" value="Clathrin_b-adaptin_app_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="7">
        <location>
            <begin position="804"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW55648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="914" mass="100397" checksum="881E13F4B12B3758" modified="2022-08-03" version="1">MAMPTMAAIAKRMAGAANDSKFFSTTKKGETHELRQELMNPSRDKKKDAMKKVIANMTVGKDVSMLFTDVVNCIQTADTQLKKLVYLYLINYAKSNPDLTILAVNAFVKDAADPNPLIRALSVRTMGCIRVDRITEYLCEPLRRCLTDEDPYVRKTAAICVSKLYDINPDLVEEQGFMDMLRDLISDSNPTVVANAIAALTEITENGKPQHAFKITKSVLQKLLAALQECNEWGQVFVLDALANYTPSDSREAEGIIERVTPRLQHANSAVVLSAVKVIMKFLEKVTDADTERTLSRKMAPPLVTLLSAEPEIQYVALRNINLIVQKRPTILANEIKVFFCKYNDPIYVKMEKLEIIIRLVSERNIEQVLLEFKEYATEVDVDFVRRSVRAIGRCAVKLERAAEKCINVLLELIQTKVNYIVQEAIIVIKDIFRKYPNQYESIIATLCENLDTLDEPEAKASMIWIIGEYAERIDNADELLDAFTDGFDDETAQVQLQLLTATVKLFLKRPNETQEMVQKVLRKATEESDNPDLRDRGYVYWRLLSANPEAANAVVLAEKPVISDDTYALDATILDELITKISTLASVYHKLPSAFVVRSTGSELRELAEEDAGDDDDEGSSDRHGEDGGSTDGPVDLLDMGGLSVSGSAPAAPAPAASSGASLVDIFGGSPTPAPAAAPAVQKKVLLNAQQGKGLVMKGCFTRRNGNFVLDVDYENLGSAPIAGVAVQLNKSTFGVVPMQQQVQFPQALAPGQSTSHALPMGVNPAFVNAAVAPNLNIQVAIKNLTSGDVLYFQSELELASIFVESGAIEKTAFIGQWQAIDAANEHYFTVPTNGRSADAIAESLNHSNVFFVAKRAVDGKEIAYFSLKSMTNVVALFEFTFDGSANARVCLKTEQKAFCGVLQKTIETLLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEN1</accession>
    <name>A0A8K1FEN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEN1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="33889" checksum="FA782810CADC886A" modified="2022-08-03" version="1">MTRGNDEIPDKWDTTRMPSVAGQVAIVTGANSGIGYEAALELARKGAHVVLACRNEERGRDAVVRIQEALKETQDGGTVEFMQVDVGDFESVKRFTTEHLGIPYTETEDGFEAMLKTNHLGPFTLTAHLFDLLKVSAPSRIVNVSSLAHRTAYSFNEDKIQITKDKYEPWLAYSNTKLANLYFTLELARRFEANNITGVTAIACHPGFATTNLSIPAIESQSRLYQAVYRVRTSLPMFQSAAMGALPTLYAATEAKSGQLIGPRGFKTWWGYPTVETPAKCANSLSAAKKLWEWSESVANTPFPIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FEP8</accession>
    <name>A0A8K1FEP8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_006877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FEP8"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16520">
        <property type="entry name" value="RING-HC_MIBs-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052079">
        <property type="entry name" value="E3_ligase/Copine_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45751">
        <property type="entry name" value="COPINE FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45751:SF11">
        <property type="entry name" value="COPINE FAMILY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="414"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="459" mass="50757" checksum="E55B5FAEDCB3C4E4" modified="2022-08-03" version="1">MGNSPSNHGDQRRRRSTATTTGPRPIAGRSTALTQMIPDQFSSMEQVTAALRRNGLESCNLIVGMDFTKSNEWSGKRTFGGRSLHTIDDPTVTNPYEDVIESIGQTLRDFDEDNVIPVYGFGDELTADNSVFTFGQTEQQPGFPLEGIRSRYREIVPNVVMAGPTSFAPIINQAVSIVNQTGQYHILVIIADGQVTRSVDIPAHAVSKNEKETIDAITYASNFPLSIIMVGVGDGPWESMIYFDNYLVHRKFDNFQFVEFHKIASSAHSRQHLLTQFALHALMEVPEQYQVIKEMGYLSKGPYQFARNVPQVMVFPAPQNVIAQSSSCSTNYSFAQPAQHNPLPVYSEATMAPAAEYPSVSSGRPSAPTFISNGDGLQTLQADTSAYASRPGMPSRQMSQAEIDLSRLQESLLCCICEDRKKDTVFQCGHETCEACASLLTQCPTCRQPIQVRIRRYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF47</accession>
    <name>A0A8K1FF47_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_003227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF47"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF34">
        <property type="entry name" value="PROTEIN ANGEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="229"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="579" mass="66596" checksum="CA8499050850191B" modified="2022-08-03" version="1">MSPPKGSPVHGEGKISLRVDQPVEGCQVMTHAFFRSVDGDIDDKVVEMRFRWYRSLLRRACANPECPRQGEGNVLLLVAKIECVLCCRLGLTRDQSCFCSPDCFRLGWHKHKQLHANIELLEASVDGKLPWKSQLYNIDALCPAREDKWIEITQQNDRTYTPSFDDVGHVIRVECQAIKYGGGHMLTKTVDTGIVLPFPPMPPKRQMLANVHEERPTPRLRQIGVFRVLTYNILAEIYATRQMYPYCPVWALNWSFRRELLQRELQSYNADIICLQEVQDDHYKKFFYPMMAEWGYEGWYLKKTRESMGLEGKVDGCAFFYKRNRFIMKEQYPLEFNEIASDYLANAMNEFDMAYPTATMADRESFHASISRMRVRIMRDNVGQIAVLEVIPSNIEVSRKHTGPLLCIANVHIFSNPKFPDVKLWQSLAMMKQIERVALARHLPIIFCGDFNSEPTSAVYELMTRNHVSIDHPDLQELTDLFASMDLDHHIGFGSAYASVFGAEPEYTNYTGHWTGVADYVWYTPELLTPFAGLKVHPPEVLESYSKTALPNCQYTSDHVPLCLDFCFKAAALMNNGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FF78</accession>
    <name>A0A8K1FF78_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_012541</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FF78"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046354">
        <property type="term" value="P:mannan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035462091" evidence="13">
        <location>
            <begin position="40"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW61350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="643" mass="72326" checksum="CF3736079E3E40B3" modified="2022-08-03" version="1">MRTMRARSLRWRGRRGLATLLLLIMVILSFALVSLPVRGEVETTDADDMDPSDEPDEPETTQGNMLVLSQNDLIEASVPSSSLPDLDGVDTTSVAYHRKEYERLKILRTNLLRDLVEKEALVHELEAQVKQAVLDIESEHTKLLKPMPSPRGIMRSLSCLGWKKTSQCQWTGRRNAALDQSCFALVPGGSAGYCEIKDDDTGDFYYVMRANCTSIPPNVMHWCQVAPQFANFPVEIEGIMALLEPPVRTTVTTRGIVMVVRSSQIERAFAHIQLLRSLGCMLPVELWYFKKERQSTFSGDLGAKAQEERESHEARIQLLGSKVQELNEAMGGAATVTTRVLDTASTQRQLPYAKIEAIAQSDFLEVLYIDVEAVTLKNPTYLFDREEFRSTGAIFWPDLFHPVTTQSNIQPASLLWEYLDMPFVDMFEQDSRQLLVHRGMAQKALRLLDLFVSNQPSIFEQLQLVDKDKDLFRLAWLRSKTAFHMVSVPPSVAGEPFPNAQDRFCGTTVVQHDLEGDMLFMHHIPTAFESQDLKHLLQFDWRSAPGNQAPPLSDAEIRELYVIHKYQLGGSLSSATTDPAETSAPKGPMCFGRERISSPGSHFSVTPWSSTPAATMLKRMDEFVRKTHQSFMAEALDAQVSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGU4</accession>
    <name>A0A8K1FGU4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGU4"/>
    <dbReference type="OrthoDB" id="166906at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="366" mass="42197" checksum="48605A91C7A502E2" modified="2022-08-03" version="1">MAEPKGPTAGSAGRTARGRRALTPEEEEQRRKINRESMQRSRLRQRGEIARMRVELRALEKQLATATEIQRQTIIQSVNPRLVEFIQLGYLTKQLQDENFWIQQELTKRWKGYERIERVVEDFFTEKVDDMDAALAAEEEQEQDDNFEPITEAAACELIRQCCQAVQLFDRATLDGDDAVVCFGWKLRYQIENGCSIRFLFSKTFPHVYPAQAMDKGWTMYRQIEINNVKSLRVLRLETIQEINEDTHVMLRDIAHPLDPGIILRTILLRFRINTERGFIGGRMAMNPTTPPRAAHIRYADVTSFTEFGYVDPSRPDLPGCHVKFGGCVDYRTTRELSSRLLTILSTAVQMEQLLMQPLTSLLPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH66</accession>
    <name>A0A8K1FH66_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_002511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH66"/>
    <dbReference type="OrthoDB" id="164361at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW63570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="145" mass="16361" checksum="C474AF1E63131191" modified="2022-08-03" version="1">MAEFQQWIHALHTDMDKQHADMERLSWASTESESDDLSFGSTPSTAMRMQALNKSKLRRKTTHKLSCSFNKLSMSPAAPLAIPERTHDFGWCDRDDRPDRAQCACGGECDEFFGDEEDVYTKCEASSAPAFAEDNADDLIFDLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH91</accession>
    <name>A0A8K1FH91_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH91"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="189" mass="20985" checksum="1D1FA3C07AC3624E" modified="2022-08-03" version="1">MASGFGELVLVVGDSHIPHRAAEIPEKFRKMLVPNKMQHILCTGNMVTKEQYDEFRSLAPNVHVVCGDTDQETSFPEKKVVTIGQFRIGLCHGHQVVPWGDQTSLAALQRKMNVDILITGHTHEYHIRTENGKWFVNPGSVTGASHSTLNTVTPSFILMAIQGPKVVAFVYEMKDGNVVVSKSEFTKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHM1</accession>
    <name>A0A8K1FHM1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_004966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHM1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW59897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="389" mass="44043" checksum="130E703FA8573C74" modified="2022-08-03" version="1">MDAHEDAMLDSFLALLEQDIHNSNASDTSETVKTTKRSATTSGLKGQVGELRDVVANLEGQLKTLRAQCGPNDPGHHRLELLLGADAEMQSRKRQRATSASVWKDVATRQYQQQQELAVRNCRLQRAVQTNERVISDVEKLLRRGQRVMAGVAPTTEYHTFSPGSIRPGVAECLVRRGIRSFNQLQEAERTQQLRFAQTEFDHVIVSSVQKHQQTRTKSVVVTVEGSFFVPVGHHDVADEVWRHFGGHNQRIKSVVDPQTEHFTAEELVQSVQMTLELPQGGAQFTTVFFPHRYDLGERQVFMLHGENCRLATDDRRFQLVSTETDKWFVMSQLDDDVDGTQVSYNDVVTVTVEAKTSHTAMQQIVDFVVQCSHVDRRQLQQEIDNLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FI26</accession>
    <name>A0A8K1FI26_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_011410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FI26"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001305">
        <property type="entry name" value="ABCG transporter ABC superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="75"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TMW64530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="582" mass="64681" checksum="3046F29EFCE686DE" modified="2022-08-03" version="1">MVPAFSKVEGACKGSTSHYQVDLSSLSMRNFFGVSPTIVAPFTDPKGPKITRSESQRFQLDQGFILSWYNLSYTVPTVRTSKTPGGNLKILRSVSGRCCPGELTAVMGPSGCGKTTLLDILADRISFGHIDGSIDVNGVKRESESFRAVTSYVAQEESLLGSFTVLETLRMAAQLSLPNSVSDTEIETKINNVTDDMGLRSCQDTIVGDLFRKGLSGGQKRRLSIAIELLSNPSILLLDEPTSGLDSSATYNVMKFIVKLCEQGKTVICTIHQPSSLVFDMFTNIMLLTRGRTVFFGPRQDALKHFAIFTYECPVYANPAEYYIDLVNLDFEGHSDVALLVSAYEVSTIAAEISLQIAADRMHKSSEKAAREVSMPSAWRQFLVLLHRNSINNIRNPGIYWVRVFMYFMLSFMVGTMYLSTNHTTSEEDLVPLLFYVQAFWCSCLSVTSYVIANFIAALPGIFLIALISTTLVVLLADLNSFGWFLLNLFLSLVVAESMMHVIAAAVPHYIIGIALGAGIFGMFMLCEGFMVPRKAIPHYWIWGYYLAFHSYSFESFMYKHLSTKNRLKQGDSRTSGHGERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FII1</accession>
    <name>A0A8K1FII1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FII1"/>
    <dbReference type="OrthoDB" id="9979246at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45948:SF2">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45948">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW65010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="37823" checksum="FDD20AB6A00F3AC5" modified="2022-08-03" version="1">MENLRFFISLWHLTALRAWDRRRKAVEEEDEATLTEFEMEFQNMHELLMNPHLRAIRVVDMARVSLARYVSSWPQASETSDLWWQERKQIAQAAQTNLLMVVPGVWIGSHVTVERYKHVAVEKGIKHIIQCTSTKPDADDDFKNGAQHARKDAFKATATRYPIIERCIKSNEHVSYSKITLLELGRMEFLVRRRDKTLVDRAEEFHAVVEFLSEVLMEIQSHQLRHLNKDAAFLSRLDGIMLHCDSGFSTSIAVCAALLMTRYYLPFDLAMRLINAARQFVSPTAYMEHCLRAYEAALRVRRHNQPVPLHQFDLGHHESNESGHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIZ4</accession>
    <name>A0A8K1FIZ4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_000280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIZ4"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF232">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYB3R-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="5">
        <location>
            <begin position="82"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW60238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="334" mass="37821" checksum="B14ACB87E1A0E39B" modified="2022-08-03" version="1">MQLDAVMAERRRLLDDEDHYRGSKKRKERKPVCKWTEKEDQMMIKLVQKYGTRHWTIIGTKLPGRNGKQCRERWHNQLDPAIRKDPWTDEEERILRESHELYGNKWAEIAKMLPGRTDNAIKNHWNSSKRRLKRSSSTVSGSLSLTRPRKRRCSSITSNGSSSDESACEATQPQDEPRVDKLDAMCSHPQRPQDLGATSPLEFNHLYTALQPPISALAISADGTLCWTPGQPPVVVTDQTRYSWQFATQTPSWLVTAAPIGSATATQLMHPKIEPADPKATQERRNKDQTTRKRLLELEAAVAMAEGPSPALKETDPRLQLLADAALLQSLCQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJM6</accession>
    <name>A0A8K1FJM6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">VLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Poli38472_002225</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJM6"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041540">
        <property type="entry name" value="VATC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18716">
        <property type="entry name" value="VATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VLRF1" evidence="16">
        <location>
            <begin position="193"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="415"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="482"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TMW63284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="584" mass="65230" checksum="32911D92CD78928F" modified="2022-08-03" version="1">MGKKVRFEGDRAYGRIGLSELSDERVAEWTVRAVAGETRRFERQTADAPTVAMDRLAIQTAIDQRSRPAVGLRCGTCDIVSFASLDEQYAHFKSDWHCANLKRKAKGAVILSEVEYSNASASKAHEHAGSSSDSSSSTSSSEEEEENEAVTTAEPVVEFSDGKSIFKVFKNILPNADTESFEPFSALDHVRQSKFRWAVFLLRSGRFAGAVFDKEKALCHKTFQRYTTRRKQGGSQAAHDASGGKAKSAGATLRRYNEAQLKQDVADLLAQWKDLLKDVELIFIACGRTDRPTFFGGKPPVLQADDSRLRRIPFATFRPTFEEVCRVRSELSSVKFAPIPVAASPVEAKTGRASASRDAQEQKIEIKADAEVGKAEEEPVVLPPLSELVRSGTLAQVKSFVEETQDIDVNVVDTNFMSALHHAVELNATQVVQYLLEHGANPSLLDLRSRPPYFLCTSKEMRNAFRRYMAANPDAWDYSASQIPSGLTDDMEQKKKEKEAEKRRRARERKKQQKKDEAEQKQKEEEAKAEQERKVAAGLACDFCGKYAGKSPFKRLEYKYCSTDCVNNHRRKLMSEAALKRLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK22</accession>
    <name>A0A8K1FK22_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000077">
        <property type="protein sequence ID" value="TMW61303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK22"/>
    <dbReference type="OrthoDB" id="431885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053145">
        <property type="entry name" value="AB_hydrolase_Est10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43265">
        <property type="entry name" value="ESTERASE ESTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43265:SF1">
        <property type="entry name" value="ESTERASE ESTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="71"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW61303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="332" mass="36049" checksum="1ED33D5A6643399A" modified="2022-08-03" version="1">MRLHKFEVDVDGADGVCAAHKLLTLLATNGEVDDVASVRFEEVMVYFHGFPDLAVHPTELDMASRMPFKLAEAWLDLGAKQDRADGVAFVTFNFGGVAGSDSMMRFEDKTITQEVEDAARICDYVRQQLLLDADKGRVHVVGLSTGAIIASLLREKGLVDTISVLAGLLDLRKGIEYDFTASQMEQFDREGACWKEFYLPEGSTWPQNACVSLDGVSVASDAELQGAVPRKLYLRLQRRYVDECLQSAPSLNIQRSVSSPTTTTGRPVAPLLVVHGEADQNVPKSDGEALFTAAAAPKHFVAIPKGNHLLSNSKHLKKAVQTLLAHIGLGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK67</accession>
    <name>A0A8K1FK67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Auxiliary Activity family 9 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK67"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035463581" description="Auxiliary Activity family 9 catalytic domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="5">
        <location>
            <begin position="40"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="357" mass="38560" checksum="143142DF06702833" modified="2022-08-03" version="1">MKVALLVASSAMVAQVHAHGYMSIPTPRSTDVFSDMTNTGACDRSQSGKVTEFKAGEEITVEWTRNNHLGGFIRYSMVPKGQDNKANFDKSTFFYTCRESNCTLKQCKDKWCGDDPGSKDYEIKCSSKVKLPDYLQAGDYVLQWTWHSAGSSYGNVGWNTGNYKTCADIRLTTSGTGTKPSCPTFVGGDRVTKMEGKSSDQCFYFDQNDLDSKEVKYGTGEEQGKEYYKYGKPKEIEKCGGGAAPAPAPAPATGANNTAPSAGGSQPSNGGSKPTPVATPVPATSSSPSRTPKPSSGGGRPSWSQKPSNGGWNQAPSDEDEDENPGKVQPPNGDEGDDEEEETERPRRKQNKWSEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FK85</accession>
    <name>A0A8K1FK85_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FK85"/>
    <dbReference type="OrthoDB" id="10249031at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.240">
        <property type="entry name" value="Transglutaminase elicitor, body domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032048">
        <property type="entry name" value="TGase_elicitor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16683">
        <property type="entry name" value="TGase_elicitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035429697" evidence="1">
        <location>
            <begin position="28"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="519" mass="56806" checksum="0EA3132682E11DF8" modified="2022-08-03" version="1">MVTVVPLHKLVAALAVKVALSATGILATPLQYNPSTPPDDIVTLSSCHPAYGLEQSADEVIQPFIPEIPICALIGNVTADVTGIIADLIDQILPDQGEDQGEETDPSQSVQQIKQSARLLEATSTDVARLEQFYGASMQKNVAQLPKSGQVVTTPWPSSYWPIYLDGINYRWNGADPSPAEKYATAFGLNVDEFTRTVSKANGVLSQASRRSCSADTDCASLNDGSACAKHLGSTTGYCIPTWFGICHAWAPAAMLEAEPVCPVTKNNVTFQPFDIKALMTEIYDGASVRTVFTGARFNGNDNAPNNRDKYGRFVDGARRDLGPGFFHIAIANIMGLRRNSFIVDVSAGSEVWNQPVKSYEILESSILTPRHAARQFYRTTRYPFNAAAANIMYVKNRFTWVVEANEDGPLVSTGRAGSFLQSQDLTYLLEVDREGNIIGGEWVGDSNSNHPDFLWFPVARPSPTTVTRATRTSWIFWTNPSTPVLSYGLGDIFALFSSVVASRSHHLWPINTNRYTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKD0</accession>
    <name>A0A8K1FKD0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_005320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKD0"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="303"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW62702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="522" mass="58187" checksum="FDD03C52AB2ED73D" modified="2022-08-03" version="1">MQYHCQVHIADSGDIDFQATLPLPQDICVVLAPISDTIARTMSTYERDLDAVDELNIDQALDLMKLQLAITEIAPADKRSLSYCHIFTSMAELCLCLERLDEASTYASLAVESEPKSHGENAKALVVLAKSKHVQGVSQDEVCGLFKQAQDKALAYLGEIHPIHFDLLMTMMEIAMTYRDLDLAFRYYQDAANVVKECYGKTSLLYADIRRQQGETLLREDRNDEATGILEECLALYERAMQQAENSSTSIELKKCAASCAYMLADAQAASSDPNTLEIAFSSAFRAFNIRKSVYSVEDEDILSSMLQLGTIANQLGDVYRAMEYYRPVLQLRKRYNHENGDSQVRKLTQVVLHLHLTYLPVDKQAILEKTKKRYASLLGQLSTVNESPNSPVEPSDESQLLVFTMKKLLESDPMEYVDSVLDRADQEFIELRRQSFMNFVRVDGTAEASSPLRLQSPRNAGSSRFASFSFGQPTLDGSNSPISSPAEVTSPLRRTSRDGTLGEFACGAQLAAILHLDALCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKT6</accession>
    <name>A0A8K1FKT6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKT6"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="36378" checksum="6F88692E5A218C50" modified="2022-08-03" version="1">MKRFASIELLARRESLLAADPVAQRVVALTQLEDELTEETDALVRHELHALHAKMRLHGDTHAGLLITLDRLTERYRSTGRLAKALETAEREMSLTEALYGQSHLQTLTWLNNTAEILWLLGRLDESEDYFTQAHRGFVEQLGDSDLSTLQVLENLTLVCSQLGRVVDTERLLRELLRLLSAVYDDGSNERVLNLTMQLGSVVIAQRRINEALEIFTTCLHLTESIYGQNHSQVAVCHDQLGRCWFLLGNMEQAETAFLRSMQLVSSSNAVLSLTERQRLHNNLAMVAIAKRSHAAVVQKLQAEYQLDTGTISVPATYTNYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLX6</accession>
    <name>A0A8K1FLX6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLX6"/>
    <dbReference type="OrthoDB" id="7785529at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="163"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW65699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="297" mass="33114" checksum="2A416BFC43BE7EE5" modified="2022-08-03" version="1">MGKLSKLFGLEKKGKISFVTDKQSYIAAIVVKATGAEKVNFFENTGSVVYPHVHKNELYKEKIVVLEIPQTLEPGLHSYPFQFHLPATAPNTFELKNDYMQNLTSFNASVKYKFMATLEVDGFLTKDLKETIEVAVQQQQRPEAVEPVRDSTILNVKSMGLFKKGTCELAAATDKNVYRAGETAQIQCEIKNHSKVGISAMRCRLYLDITVPVSYGRHTFEREIAEAKFPGVAAGKEETQSLPFQLVSKLNGGVMLPSSTGRNFECAYRIMIDGDISWGKDIKLTLPINIEPTVLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMC0</accession>
    <name>A0A8K1FMC0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_002449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24822at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044591">
        <property type="entry name" value="RUK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562">
        <property type="entry name" value="SERINE/THREONINE-KINASE ULK4-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46562:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ULK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="300"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW63508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1437" mass="159729" checksum="4B4F35FECA705616" modified="2022-08-03" version="1">MENYNIYDEIGRGRHSFVYKARRKRSVEFVAVKSTAKSRMEKILNEVQILHRLHSRYVLKFFNWYESQNHIWIIFEYCIGGDLLNLITQDRQLPEPTVKAFGWELMAGLQYLHSNGILFCDLKPANVLIDEAGSLKLADFGLARRIPTNDTARSKPLEHGTPTYMAPELFQQPPIHSFASEFWALGCLLFELCTGRAPFTHTIFPELVRMIQTVPVELPPPGFDMSPLFANLLGRLLEKDPYKRITWEELVHHPFWTDLPKLEHVELPPQQLFEAARPDRHNELAADSESVAIAEAPALVGTSKQEQQLSETNDGDNTVSGGTSEDDEEQVTGGQHDDEPSDHSDESDRDSGKSDEKQAARVRPVSAPAQVLASRPIIRQNGEVSDRETGKMEPKAEEKNGLHRKAPNTAPPGPITKRKVSDGAPRGWNSTLKKAPRLLFTATDCTVKPIAFSLDIEDVDLPSVDPQLLEFEEIHSDTLLTCPTEELEDHLKSIYISLKSPEASAEEMANVLSYLFKLCLKPKLANVIVNSSILTLLTRLLTQLDGREHDATSLLISKITLVLGVLFRFATFIAATSPEQIQSLVLSLEDNLANQRESQVMNMKRRSASSCLGELLFYSATQKGGGVPHEGIECILPLLEDSDSVVAHYAIRTLSNILARCLDSVTLQKLINENLVLALQRTLASCDLGAEDSIPLRTTVTQALAQVFRHVRFPTSKSFPPRMKTALLMLLSRPNALDSLWRGVQSERVSLDLAIASFNVLNGYLEMGLESDRDGEDQAHIGDHRRILLEKIANPAQLRAILDTRSRFDEDMRNSGRTDAIATAPTDATDRRYHGDDDSLPGMLRAKTLLFVYFGMHRSKKFVEICISESILLLVERSLSPYASSIRSPQPSPTKASPSSAMRRLSRVDQYVVDCGLNAIRFFIRTALKLGAECISGRRDIDYEVEREHSTISAAPFGLFEQLLKHPICRSQVVGYFLANKGKEFTFFIRLMAKLLTSFSGEGLLAMGGTVGGVISGILLRLFQSSSTEAAALLSVEASEIFSHLLPALVTQLQEVGSAEDNETEDEHKVNCIRLVYSILLHLDPEFVEHDEQLKVKFLSDHLLPCFESLLDPSRQSENVWRFSVELLFGLASQDDSHFQEIVSLDLAKQVVALLGASASLRENTLPPSVPGVVKLFVDWAKKTQQLGLLYRQGLATHVLAALESVCLNDDRAASTCELLDILYQLLYSRYEDHRKAKGSLLIDADFEPLVRSGPILLQLCARSTENSSQLAKTSEKKSKDPSAPSDVVEVSSRCLVYLSQIFGEKLNNVLFTGSSQKKGYIIPGTDGLDRCIVLILKEQASDSPVLLRLLLTLKNCLRCDGATRSGTRSGNSQTLRWLTENADVLLAVRRITKGVLATKASRDANTTQEQIKKTAAEIVRLAQASSTKSPHGEQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN15</accession>
    <name>A0A8K1FN15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW68896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN15"/>
    <dbReference type="OrthoDB" id="100767at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="56033" checksum="4E4F00BA48A92C1F" modified="2022-08-03" version="1">MSYEDPQLEVASRSFGDGSPDGNQSGSLDDQVHRMRIFPRHQVPQVRLIREPRALFIAVNIREVALLPGDRLILRDGSNDTEITITRQNQSIAKRVQHRRVLWNHPFLMTGDKVVVEYWPSLTTLVLPINRKQLDNAVAVIDSYTFAYDARGRRRRGSDDDYDRLGITQVPQAESIVGSKNEMKPAVCFKKSEPRMYCRARAVARLLIRNEGDQQWHHHAMMNPSSRWTYCTGWLVGRENHMMTNYHCVRALMRRSGRVFPFIQNQGTASNDAGGGNDTDTSVNFMAESSTCGDVGYMGERVGVVEATRAKIVAMSEALDYSLLQLEPNNTSVDLSSKYGYLTLRASGPVDGEAIYIPQHPNGEPKMIAAISDGQPAFIRVLPIANSTSSSGSGSMEQQSNDSDGSGSLSDATYDNVSVWYNADTAPGSSGSPVLSQRDHTVVALHHAGGAIVTSSDPTANQQAMNIGIRIDAIGRDLQQRRVLPPCAFARDCRAKTKDPCCSNTKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FN95</accession>
    <name>A0A8K1FN95_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_008284</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FN95"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW65642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="360" mass="41614" checksum="9C26FD4238109290" modified="2022-08-03" version="1">MTSTKASQRVEFPNVHARPEQQTQVGKVRRHIVLFAFYFLWVVGFMGYGAISALSAATVGHAVIQGDASYVPLVVRVYLSLMVLYYSYHLTVLRNGQPKWKALHALCRSTLMKYPYFRHQICIFEEFEEESLKNPEKAFVKPKDKAIFAFHPHGILTCGWTVNGSFSMRFDQADERWLVAENLFWFPILRDALHWMGFDDVHKDTFVKHMKDDRNLCFVPGGFEEATIYVHGKHRSYLKRKFGFIKLALQYGYKIHPVYTFGEELTYKTFTPLLKFRLWLNTLKIPGAVFSGRTLCPILPLNDCEMTTVVGKAVQMPKIENPSKEEVAKYHAIYVQAVVDLFERNKVKYAADPSAELEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNQ9</accession>
    <name>A0A8K1FNQ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNQ9"/>
    <dbReference type="OrthoDB" id="183995at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="309" mass="34268" checksum="A596711EB4611450" modified="2022-08-03" version="1">MELSEDVVLTTAGTDGAVSVRAGSTVRVVHDRSDSAVVDVLLPGHGVYPVDRRKFRSESPHASLSYVSSLVLRIDADTEDFNGILSLLKLVGKHLKQCKIIHDETSDVVLYPIKLCEVLRECPNAEAVELIGLHVTDISQLSGFVETHDCRFSVLEFDKFRLDSDDDLENFFEALSNDSTRMSQQLLQLCVEISDAVVSSTTLAAMQKMLLANRTLEVFMLGVSQNHMDMFKQGLYQLPPVYLPTPYKSFPLRAKLAFISVVHAEANESCAISRLDSGVISTVFEFAAPSPKRFIQVYAAAEPFHTEMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPL4</accession>
    <name>A0A8K1FPL4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPL4"/>
    <dbReference type="OrthoDB" id="124672at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="52017" checksum="ED270911E4DAA741" modified="2022-08-03" version="1">MTTKTTTKTTTKTVAANKEVDEVVVDMEVAMEEVEGDDDGDDENENELEVQVPVEEKFPSHLKIRKADCARVNAKNLKLLLMVQNEIGQIVGYTLTESENHAQTRGLLEKVVRDRFLATPQCGDKCIICDNVNRERHMLKEVFGEKACVRQDPFHVIQRVSDHIVKGKGKAVAKQLSNAFVNPDDIKTIANWNGCINSNIEQIKRGDLSVPCNTYEEGGSRVKIVSTSQLEGLHACLKRLLTRTVSLQVGLRMLDIFLMKYNLRIGAKFGRNPDIRDMNFSQLCQLSLGTHDANVSTSREAEFALDVLGKGCDLLDKDHEMPVEFRHTTSMDFPFKRWSFAFPSLSVDDAEFMRRTEEMEEKERRSKAFSVKTFRATSVAIDKNAVFRSLKLDKDDVEDCGPPSRDEYAAMTLIVRYLKSFATERHELERRKSPAVVAALFNHLGDSGRAIVLGRGQEIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQY3</accession>
    <name>A0A8K1FQY3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW67048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQY3"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000006">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="10"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW67048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="242" mass="26931" checksum="97660BB9DA7F0D40" modified="2022-08-03" version="1">MSDDGHGGKRWFPLESNPAVMNTYVEKLGFPTSDFSFCDVLSTEDWALDMVPKPVVGVLMLFPIKKHTEAFAKEEAARIEKDGQVVSPHVYYMKQTVGNACGTIGLLHAIGNMRQHVTIPATSYLGKLFNQTVGQTPDKIADYLEEDDELEDTHESAAQEGQSEQVEDVDDPVDTHFICFSCVDGHLYELDGRKKFPINHGPSSQETLLSDACKVIQQFMVRDEGEVRFTILALAKTADDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FR29</accession>
    <name>A0A8K1FR29_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FR29"/>
    <dbReference type="OrthoDB" id="6131344at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124:SF14">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_25, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="231" mass="25465" checksum="B178CA8DDF4A4978" modified="2022-08-03" version="1">MRRMRRAARESGVFGMQHSSASWVGSFKSVDVTLALINNGVDLHGAFNHDSSLHANTFYRHNKVVETLVKDGYVDVDARGEDGVTLLMVAARRQTMQRSGLDIASLLVAHGTNVREQTDSGEIAFHYLVKNQIDKKVVALLVAQDPELINLSDNNGATRLLSSMVQTTDTSFASLAYRIDILLSHGADPFIQSHSVESASQVLMATNQGRAYIASRPHYFPKNKFIKCSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C254</accession>
    <name>A0A8K1C254_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000151">
        <property type="protein sequence ID" value="TMW54983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C254"/>
    <dbReference type="OrthoDB" id="427735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035449177" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW54983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="591" mass="64386" checksum="6C69B38A93C11D14" modified="2022-08-03" version="1">MRVLASSAAALSLLSLATAANVSVNGWYPCGFSRDLVAQFYNGDADVNAIFECAQVRVPLCYDGVCKSDREIDVFVKRLVADDADTAVWMLHGGPGASSAQFELNMVNMYEVLEGTASVYAMDHRGTGRSALLTCEAAQAFTGGSPDGTQLDFSEVANCVKDILFQIENQTVAFSTTSAAKDVALLTSQLNKHESVFVYGSEYGSYVTERLMHLSPGNAKGYILDGVIAETNDSYARVGSQRDGPGRLLAKLCEDNSACSKAYGVNGSLYDSWLATYAALDNATVGENACADLVRGDFEGIEPSTVLRSYFSMVVDDPYQRMLLPAMFQMLGRCNSTDELSLRILLTLSAENSLYELLNDVEDDEKSLDEPVDTVIETSMFLSHLVKSSELWGVPSPKWEDEKAAVDAGVFTTYSTEDYAWHCILSGNKSDPSCGALVELGQQLDPPVDLKTFNYTPFLYKPDALYRKPATIPHGASVLVISGKLDFDTLHANAVKQFEEMKGDNKLLVEFEYGTHLSGVMPTSIDDITFCGPSIIASYIKTGGDVSKTDVSCLDDVPEINFDPQQVQDLLRVMLGGGRKHKQHHMALHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C264</accession>
    <name>A0A8K1C264_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_013838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000149">
        <property type="protein sequence ID" value="TMW55076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C264"/>
    <dbReference type="OrthoDB" id="72944at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="645"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="809"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="872"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="564"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="964" mass="108715" checksum="820BEB87A04E2454" modified="2022-08-03" version="1">MSAGIARQDAALRRSLTTLTLPTGANANTGDRKPSTNAPPPRGDIESTVPIREDGAGDPSIDDDEGEDEHDVESTKRLSLQQQLEMLRGKLARRNKILEVVRRAYYHDVIVVKEELRHVRQQQPSTLHSYHTLGSQSTLSFHHSSTASLAIPPSSSRSTTSGAPPSSRYDDRLASVPSIDLRDVLPLFAPSETVLKVHPCETCGGHLELVHGESKELMAARQEMARATKGEAQMKTIVHRLRVEAKEMEDVNEALQQRVKALVKENSYALEQLQAARKIERDQKAILTTLRSKLQLAQNTQEDLDHLTAEYKDVKQQLIRSNHDRDIFSASNNHLKEELSEVNKMLHQVKVEKAQIESDFGLTHYKLQEELKTTRQLREDLANERAMLNAKTALSDELQKSLTTLKDEFAVTLQRTEQAKRQLEDQLADEERSIEEMQEQNLEFRKTNKRLLKELEQLQRDPLGLSSPSDFRSSGNGSTAAASTSNDPKTLIRKKIEGLQMHLEAALMREHDLLGLLTRQRDAATPAPTSAATPSKPQLRKKLSRMPSTTVITRFVPPPDTPAGSTNGVSNETSSSNSGNSGNGENSEGSGEVSRRRPRFGRGGSDEWSGSPSELAEAGEDGMADFDEKSFEAYHQEIHHLMVELEEGKDKHQKQQKVITDLERKNQTLLDRLEESKLAIETLNGSLTALKSRLNQDNAGAAEQLEDMARQIEDGKLDQLYESERGIILIHFLRAISNEVFRFSENQALEFEFDLERPVIEEENSSESYLSPELLMKKRELRKKVLMDKAMKKFSQLCHSRAEIIALEIKKLTEHLDRLRMDLDQAENKIDSDQFHIRTLEAEVSKLKLTIEVGRTNFARSERALKIVSDELQSYQTTAVNQTEEIKTMKQEIDTFKEDERRLTMILFEKTKAWEKEIGINEKVRLSEGFDAMSEGFDAMRTYMPVVPLFSALNGLPVSNPSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3J9</accession>
    <name>A0A8K1C3J9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_008514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3J9"/>
    <dbReference type="OrthoDB" id="104223at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035471946" description="Peptidase S1 domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="43"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="263"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW55866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="39802" checksum="D235F60072BFA167" modified="2022-08-03" version="1">MQIHRILSLLAACAVASTSALDFSAVSAKVSDRIAESTNEDRIYGGTEASASKYPYIASIRKSAEGDTYCGGALIAPQYVITAAHCIKNTTMFVSLGSKFSKGSAEGVRLEVKESYIHPQYNAETHVNDVAILKLEKTAAIMPVQLGTADDAKDDSMAVVRGWGVTEAKAPSSVLLEVAIRIISNDQCNKSYDGRITKEMICAGEGAGKDSCQGDSGGPLVANDKLIGVVSWGGECGVQAGVYARLSTVLDFIKDKTGVGAGSTAPSASPAPSSAAPAPSSAAPAPSSAAPSLTPAPAASSAAPSTEEPEPTETPNQKNTPAPTTKTPTPAPSATTKAPTPSSTAPSKGDDDYDVTPAPSASKTTPVPSADKGTGASSPAPTPSKKKDCKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3L8</accession>
    <name>A0A8K1C3L8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3L8"/>
    <dbReference type="OrthoDB" id="74860at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="423" mass="47403" checksum="457A5C319FCE57DE" modified="2022-08-03" version="1">MYAFPAHSHSVAIAMDAVVATHRRMRRRPGETAGDTETMDATAASGSKALDPAQEDDVDAYTAQQLVSIRTSGWLALSLYTVLALAILWMTMQHFRHNSSRRKKVFHIILFFSIGFNLPDPLGWLLWPETESWVYTYPMRIYAVLLQSVCKSMISILWSEVVSAGQSYERRRTTTYVSVFNGILLVWAIAVPILLMQYENNLDGQYAFMDSSLRGVVTYSGVAVIFIYGLLLSYQGLRLRRRLLLARGTVPVGSVEKSLSQLLLTVCVIVFSDLLRIVSLILNELDVRMSMVSFLVCNNLIPTIFPTICMMYLMRRYTKQPDQQHDPLATTRGAPFTSVSVKPERGRTATLSRYMSDEHRGSDLSDSSTPVLGMSKYALPTTQAGHVDPQDYEAGHGHPVIMADSSTSQHAMLTPTSYWARGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C479</accession>
    <name>A0A8K1C479_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_008788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C479"/>
    <dbReference type="OrthoDB" id="152254at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="223" mass="25917" checksum="32328C9B79B39B03" modified="2022-08-03" version="1">MDIRRLLHNPDDGSWFVIGETKSESEMNEFRRSLKRNAIINTHLVNCTMSHDNEDAASEEHKMKVQWTKCTSALCHPKHDDEPCEPRKRRSCPVQLRMSTCQLTYKGVICQAYQHLSEEHDSAEPMQSSVTEEMKTHIIRMLDDNADVKPMVIYKELQVLHRKGEFGYDLMPTKIQLRNALTYLRSRKFKSSPRSSTSSRKRRFDSFSEGSASPSPEEHRMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4J6</accession>
    <name>A0A8K1C4J6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008946</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4J6"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08283">
        <property type="entry name" value="FDH_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="59"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="231"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="430" mass="47139" checksum="12D1AF0004F74142" modified="2022-08-03" version="1">MSVMNAAAKIADNMLGKREVGETSTQPKVSDTETMKAIVWKSAKKVACEVVPKPILTHAKDVVVRVTACAICSGSDGHLYSGEVVTMDDGAILGHEACGVVESVGNDVHKFKPGDRVVIAFDIACGECEFCHRQEYSGCDRSNDSHLFEEMYGGHPAAAIYGYSRLMGKVPGSQAEYVRVPFADVNLYPIPDSVPDEKALYVSDVLSTAFHATELGEVGEGDTVAIWGLGPIGLYAAAWSKLKGAKRVIGVDLVPERLTIAREKFGLEVFDRSDLSSAQVLSKLRDLLPRGGVDVAIDATGFRFSQSWMHTIERAIGMETDTPEIIGECMNIVRKYGRVAIIADYIGYANHFPVGHVMMKHLTVRSGQCPVQKYFKRVMEAIEKGQIDPTLMITNRLTLEQVPEAYDQLFYKQKGYLKVFITPQTTKSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4U5</accession>
    <name>A0A8K1C4U5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_006466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4U5"/>
    <dbReference type="OrthoDB" id="354at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="72" mass="8379" checksum="EBD8915ED82FCA05" modified="2022-08-03" version="1">MPTANKGVLVKCDPATKQYLLHLNETAVQHRFVIEDLDETHLFIVPDPKVIAFIEKKMDEWNEKNTYQPPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C4X3</accession>
    <name>A0A8K1C4X3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C4X3"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="222" mass="23462" checksum="358B49E347CB5D97" modified="2022-08-03" version="1">MIMSRAFGELMAGTFITFSLAFLVGTVVNNSEGCRTVIDGSFCQQGGVTQSIDTTSSTSNGQCQSVDVGKTTGAAVLTTVLTKVVSIAGSYAESMAKDDAKRKSMLLGGRLLATLALLGFGIGYSYAIASSTGDKEMANRCFETIGIVLGPSWAADQVTDMISVWAQRVGIYFVQCTPKQTMGIKAEQAAGSIVRPVERPLEPPQLDTMVHETDIQVTTAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C541</accession>
    <name>A0A8K1C541_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="5 14">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Poli38472_006478</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:31239"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62626"/>
            <dbReference type="ChEBI" id="CHEBI:62631"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:31240"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:19866"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="5 14"/>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C541"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000008">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="16">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="17">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TMW56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="407" mass="45302" checksum="185B59C03DEDA7C8" modified="2022-08-03" version="1">MVEVATAVRSLAIACVAAAAIRYVLARKQALQKARPFPSKRTPLKRVSLDQLPKLKNDLLLRALKGEKTERVPVWCMRQAGRHLPEFRALRNAGYNFFTMCEVPELAVEVSLQPLRRYHMDAVIIFSDILVIPQAMGMEVKMVAGVGPVLPSPIREPADIDKLDLNPNIEEKLGYMLDALNLARQKINGEVPLIGFVGAPVTLLCYMIEGGGSRTKAIFKTFLYEQPKAAHNILQAITDVCVNFLIAQQKAGAQALQVFESVAAEVLTQEHFYEFCFPYLEQIAARVKDAAPSTPIVCFSKGTPYAYEKLSHTQYDCLGLDWQTDPAEARKLVNGRVSLQGNFDSSTIYASPDIIRTQVKKMLKSFGTQRYVANFGHGCFPDMKPEHVDTFIKAVQEISLEMNANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5E5</accession>
    <name>A0A8K1C5E5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sjoegren syndrome/scleroderma autoantigen 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_006628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5E5"/>
    <dbReference type="OrthoDB" id="28939at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051888">
        <property type="entry name" value="UPF0148_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537:SF1">
        <property type="entry name" value="PROTEIN ZNRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537">
        <property type="entry name" value="SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22339" checksum="389C5DCD01BD20C6" modified="2022-08-03" version="1">MDSTAAEAKYKKRDDASARLGEKLLQGWTMLGVHCPSDECFTPLVRNKQGQMFCVSCNRFAITEEEAKKQQEEQEAKEREEQQQLEAAKAAQEQLARQQAERERHWQIQQQQQQAAVTPARATPVANGPVKRTSADAALSTAGDDEFVQACRRQTLAAMYKKLEELTNSISTTDHLERVLSTTKAINELANAIQTLSSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C5P2</accession>
    <name>A0A8K1C5P2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000144">
        <property type="protein sequence ID" value="TMW56905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C5P2"/>
    <dbReference type="OrthoDB" id="79466at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW56905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="25408" checksum="DAFF602C153BDA08" modified="2022-08-03" version="1">MRNAKYSRVPVDADGGRYRTQRNRGSCAMFFRLIMFHILNILLAGAGHLTVTIGFVLGVCLIPFCCVGLVVIRITLYLVGVLAEYDASLYNFVSTDDDYIYPVVPHEAESFSLSGLRLAPDLSSFSMEAFFVAFYLYAIKTVMASLSTISLALLMALPIVLADRNAYRDVSTLELVLISIALTLVGVGFMRFSAYLSRSATRFFCCEKFAIHSYATPSEPIYHAVKDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C6A4</accession>
    <name>A0A8K1C6A4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_006842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000145">
        <property type="protein sequence ID" value="TMW56832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C6A4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW56832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="17069" checksum="6D05CF0D73326124" modified="2022-08-03" version="1">MDEQVRKYNTLIRELLDMISADLPGNKMVETIRRRFRVALACDRTYILEETSPEMLEYRDIIAEERWDDLIYKDWESEIDKKDDALMYEIDNRSLRDMISLLRSLWENYNDEQKAYVKKSMKRLLSHCVKYLRFKEEGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C7Q3</accession>
    <name>A0A8K1C7Q3_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_013459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000113">
        <property type="protein sequence ID" value="TMW57985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C7Q3"/>
    <dbReference type="OrthoDB" id="94331at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW57985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="189" mass="21453" checksum="793441A70624CC0D" modified="2022-08-03" version="1">METIEFIDYHEIADAAENVYLRPVSKNFQSVDSNIKPAALFQVTGAHKHPCKQKGLHDVLSELGNPTHPRLYFVVPPDRFTSFRYQPYLNAKGKAMREPTYVNGKDGEVCGCTDWQDRGVKVFNTPPTEKCKTVNPKWIEKIVPTLDFLKKACPTTYTYPYDDMTSTFVCGGEKKYRITFCPMGDPISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C987</accession>
    <name>A0A8K1C987_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_010295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C987"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00043">
        <property type="entry name" value="rRNA maturation RNase YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="ENDORIBONUCLEASE YBEY, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986:SF1">
        <property type="entry name" value="ENDORIBONUCLEASE YBEY, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW58736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="187" mass="21581" checksum="AAB0D0DF822E7523" modified="2022-08-03" version="1">MVQVAKALAPQLARFPVCVPALDAQVKAMVRAINCPGGPWDIGVMLTTNEHVHRLNRKYRRKDKPTDILSFPFHKVCRHFDGVWMQTRCAHGLINTAQVSRPGRFPVVRSREERYLGDIYISLPYVYDQYLDPEETEVTSLEQRMPILFAHGICHLLGYDHETDADYERMAKAEAFILGRYESYLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9D2</accession>
    <name>A0A8K1C9D2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_006941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW58796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9D2"/>
    <dbReference type="OrthoDB" id="75615at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW58796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34239" checksum="D9188FCEBF67BF91" modified="2022-08-03" version="1">MLAGNRRSARIASELKLKEKTEAYESMMEHFQLRKLHRTFSADDGSRFSSPQSTSSMREQTPSEDQQVHQFRRTWPLDQGRGALDDSTCQDEYKGTTPLQNLFSTFSVLLGSVILAIVFGNVAMLVSNFNANSTNYQRKMEVVFATMNKLQLPHDLRERIHLYYDHLWQEYESLDGDIVKFSKELTHTLALEVGLYRYMNLIMKVPYWRECSPDFGEIGEEMYMVNRGLCEFADVTYSEDFSTARDQNHVGPTGMGSVLDTNEDEGIDQEQLHQLPRVVQSPSSPQSLKLRLQAIQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Z1</accession>
    <name>A0A8K1C9Z1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Z1"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="83" mass="9139" checksum="7A591110B9975987" modified="2022-08-03" version="1">MEDKANVAVIHGTGEKTSVSGVSKEKKGAIDLPAEQKDDMRLSEEERENGISFQEKLERFALNHGCQVGSRAHPTFENQALNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C9Z3</accession>
    <name>A0A8K1C9Z3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_004371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C9Z3"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF5">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW59302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="59437" checksum="DB34472FB442383C" modified="2022-08-03" version="1">MKTTDRVSTDDTHLQKVDSGAFHAIKSPAVESDGLELGGALRPGGAPSVFSLKHIGLLAHIASVGVVYGTVYGVIYAVLNNYLAMSATLVATAQALIRVPRALRMIFAVCSDCYPIFGYRRRPYLLIGWIMTFVSCFLMAVWPIGDPATTDPDASDNGIKLIFLMMFANLGTVIAFGASDGYMVELAQREPELTRGTVQSNVSTVRQVFMILSAFMTGLGLNGVDYGGSFSWTMGFNAIMGVCAAFSFVTIPLCWFCITEEKVSEGKSGSEFFKGLFKIIQSRVIFQLIALRFFRQIFSLFSVTADSLIQSLWAKVEPLNSGVADMLSSVISAVSIFIVKKYGLAWDWRLIVITCQVFVVALDCIPTFFTIWNVFRSQWFWLGVPLLAEFPNSIGDFIAGLYVVEVTDEGFEATIMGLMVSISAIGTPFATVMTKSVSSYFDIERPYIKKDDHHVHSQLTYAYIIAYIVNLFSLVFVVFWLPRQKAEVRALKRTGGSNKVLGSITVFYLVFAFCWTVMTNILSLSASTKCLRIAGGTGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAN1</accession>
    <name>A0A8K1CAN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAN1"/>
    <dbReference type="OrthoDB" id="102511at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="613" mass="69663" checksum="D421EF5A18B35C7E" modified="2022-08-03" version="1">MKGHHYLFSTNHKQVEVSDGHQNAGSFCMGKRAMDTMDTWWMDVEADVEKNRHVKDPFREAYVRLVGTPFDRFLENEGRGDDGNEGRADELDPVALRHEISIRSQQVHLRLEILRRQVHTLCEESEAFLSSRNRREKASSRSKQKTPEDIPQEIAADPVIDVEQLLHRLQLFEKGELSSSDIQKSWQWNCDCESHEVARIDGHLNLLRQTMNERFIQHLETRPSIYGPLQTYTEMLQGETSDEQDDPAFLQECMKSIKPFFLEDFIQEDFSMSHHSDNQEEFVDVDEPMDVDDECDIAQAESPVERATEASPVLGASCEVPRECEEVSPPNPLHSAPSQPRDCISSPRYSVSSRRQSNNLFSVEKTKAKRDTFRAEAQQVEPQETRPTTNPRQEAIKSSRSTIDEQNRQLLVDCTSWLRFSHSILDPGVDLLSLRESGIDGDEDAEPGVLNIQYSRDVSVMIETRSTISVEDVPRLEEHECDPLVRRDVCDVLEGDSQYPYITKRQRGSQPPKPSKKPKLAITSSGVRRTTLRMLIDGITLTLRRVAQTSCVSYLSSIAKTLSAPASPQRHFVALVFAASIANTSDREHDAEKISITLESARSGDVKVICRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAT8</accession>
    <name>A0A8K1CAT8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAT8"/>
    <dbReference type="OrthoDB" id="153648at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="540"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="687" mass="77281" checksum="D9438B4546B35703" modified="2022-08-03" version="1">MSLRISRPSTSTASEPSRYTSSHRKMPSNSRSNATPTRYRSVSGPQRNVRISDKRLMDQARDVTARIQWSKLLQRTDATGNGWNVVEELNQVSVFTKQDSQKYCVLAVGILPCSMAELLPMFHSSSNYEYNHKMRGLCGKEYDGGALLHEIDLEDEDIRPSDDIELDGVRQVTVKTASFQRAKWLAAPEEWCFLDVQRRDEEKQVYEKLMSTLLPDDVLPYKVSKRTKYLHNVIAGFMIKPDDGEKGTTRPGKPTTRVHFYAEMSSARSPMFELPPSSAIATEQSIKKRVFGLARNCQRFIHLVRRRRLGVQVYIDQNRFWPPPSGRCSRCSKMQLLGKLCRLCGHTVCESCSSKHERERILRTSRHFRLDTVRVCNRCIARVDAANYASVAQNGIKPAQVIPDSASTDPPAPLLTDLLQDALANASSDQRKLSVLNVIKCVLKQENTVRDSSDRSANGSLLLSQKEEEEVVQALHRTLSPGNNPADSYEITSNAEARSYQVEPGNDTSVQMAYPIPENENKRIEAIKESGVREMGKIEELDIICNLAIKELGCFASMITIVDKDQLYIAASNISMLEQKSFDRADSFCAHTIMDNKPLVVPHPEADVRFHQCKPVQVFKAQYYCGFPLLAEDNSTVIGSVCCVDQKSRDLTESQYAALSKLAETASKVVKIQAAQRRQRKAAMKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CAU7</accession>
    <name>A0A8K1CAU7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_005018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CAU7"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451135" description="DJ-1/PfpI domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="230"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="560" mass="58433" checksum="42D919E84F2BEAD0" modified="2022-08-03" version="1">MILDRALVIGIILFQNVTTLDFMGPATYLEMIQPMLGQKTDFYTISDKVGGPIQPSYLMPLHASVTMEEAPRKWDILIIPGGPGATPYAKNEKLVSYARAAAENATDVLTVCTGGRILGATGLLDGKSATTNKIRFNEIAATYPNVKWVPHARWVEDGKWWTSSGVSAGLDMGHAYVAKKFGAEAATRIARTIEYVATTDGSEDPFAEITTGSPAPAASLPPVSAEAPIRVGVILFNNVTTLDFMGPATYLEFIQTMLGRKVEFTAIAEKAGAVQPLNLVPLHATVSMDQASQEWDILIIPGGPGAIPFAKNEKLVSYVRGAAEKSKDVLTVCTGGRILGATGLIDGKKATTNKLRFKEIAKDFPKVNWIEKARWVEDGKWWTSSGVSAGLDMGHAYVTAKFGKAVAERIARTIEYVADTDSLNDPFVSSVTASPAPLPGSGSPAPSTGTPTPGVPSPSSGAPATSVPGASSAAPAPSSGAPVPTTGAPLPSSGVPAPLPSATTAPGTPAPSTDLPGVVKPNPGATTCVRGSQGRKDLDAWCTSNCAMNFCPQSHCEPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB16</accession>
    <name>A0A8K1CB16_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CB16"/>
    <dbReference type="OrthoDB" id="2099750at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="210" mass="24753" checksum="EACFC9AA6DA7666A" modified="2022-08-03" version="1">MSPFEPSKLFVRKAAWEDAAEVGEILVGGFHDSPFWDCIDLQTKHPEAEMFFFKQWARIMFGNSFLILYDDQVIGHYSITPENDSGPTFWRLMQYGFYQPPFRYGWEFTTHAMDLVDSSCCTRDHVLSRRPPVVMLDAFAIKQEWRGRGIGKHILKQFILQGHSRMVLLAHEKKAVDLYEKVGFRTLDQRVVRTSYNREYENWVMENEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CB56</accession>
    <name>A0A8K1CB56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="518"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1534"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1711"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1736" mass="194042" checksum="5C5111449AB6D6D0" modified="2022-08-03" version="1">MAVDMAVRSVLLSDVQSVLSIARRRYGYLLVSQQAKDVEDQQQSSIFQGFTVLRTRLQRCENLAELSASSALRPFLDLIRHEHTSSTLTGAALEAVQNFLQCWNWKATHAAVSDVLSDIVDAVSQCRFQETNAESDQNVLVLVVHVLYTVLTLPCASKLSDHSMWQLVESLYALSRANRNDPHITLSLRSTATSFLHRAVEIIFQNPNVYAESVVTRGADRGFGLPCAIKIVGFLCQKLQPRGSGTNVTASSASSLPTRREVMLSFSLMQQALTACNEQLLADVPSLMMFIKDDLCSALLRYCRLGASVDMKIPVLCLGIIRLLWTKLRPLLKMQFEALINGVFCHTLHWTIAHLDLSHPIFPQSDDVTPPSSLANGDADRRVEAVREEFTGELITLNKLFAVSFEILDCLVDLLAEPTILPDLYVNYDCDGNRSDLMNSVFDLLSHAIEKSHAACQETEDEVHFMWARAMGELAMKGIFNSLYVLYTRGQHKPTPREVVDNSEGQHADATPAVTAEVLYRKRQRKKIFQRGIQEFNRKPLSGIKYLQQNSFLPSPLDTKSLATFLRSLPPGLNKASVGIYLGAMGKEVKDFEKTEIHEADTIEFHRDVLRCFVRSFNFEGESIVAALRMFLASFRLPGEAQQIDRILNTFSEQVFEQSRDRFLMASVDVAYLLSFSLIMLNTDLHNPNIRPEKKMKLDDFIKNNRNYGEEVSKKQDLPNDFLTELYDAIAKEQIKTCEDDGKHGEVTMDRWKDLLIQAESHPLNSRLITHQQLSSPAHNTPRRQTQLSQQPLKRKTPRRTTMPALSQVHAASDDEVEYMAEEHPDQLHQTGSLFGKERDTAHHYDHHIFELVKPHLVRAFSSVFLQFVRASKQSESFEMPGSLERRGEMSGYLPEKNMLQLACNGFVLTAAVASHHRLLDDFNQLFTTICSFTALYPSATYPLAYNARANGVTQYCLNQSAPVATAAMLKLVGTCARSIRSDSWTHVFHAISTLREFRALPDRVLYAAHGSVEGLLSAEECVEMLALVYRSKEELERREALKAREASGESSASGFFSGVAWLMSAFDGATSTAASHASTNAHSSGPLKPPALPILLSPVDMALSGHDLVIRSSDTERQLPTSPRGDRVDAFVNSGWIRQTLLPYRLESVIEDVAALPASALVEVVKALDQEITSVLTVSAPANNADDIDSRRLTPAGCVFFEHLLASILGRIQRDNLAENSDDLWDLIRQHYFKLLTLLRPILLKNQPINGINFENASFTLEKALEGLFSLVWRARSGKAFDLAVKFLTALVDVSVDDELVRPYLAAIMSGLKRSADAIDLRAARFDRGDWLTVSNLIGWAVEQPHASTHAFAFVEKLVASEVWLSEDGLISVMDLYTRVLMFALTQRENATVRWPSRRPMELLSVLYDRLHEDEVEVEEEERLRQLGGMALVCRRHVQILVFEQTTGQGPRALQASEHALAALEYLGHMVKSSTSRSSLTGGAWLDVLSFGLLNIGSAMLHRRTSHQHAVEEGEAAGPFVFYERNLPQSLAIEATGDSARPTQQQSRRRRPSAVKDPNALKPHIIIVELLSWVVCEQLDQLLLHPRFAMVWDELIDVLLSFIDFTKVDRRDGPAEEMMSLALERRSVLSAHEEIVEHVNSIIRRLTVLQDRHEQEAEATPEGVAPDLSSARFHALMHVLVEKCQSKGAGYFELLFPSKEEATIAEEQVAIEGQEHPAPADSEGAAPAEQSATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBC8</accession>
    <name>A0A8K1CBC8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBC8"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW59868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="368" mass="42029" checksum="8CF188D9DECCE369" modified="2022-08-03" version="1">MLEMDDDPKTLCALLDALDETPMAQLHVQKSSEEQNKHSGCSCGLPAKKKRAVSSFARQRQRIFDLQQEIEQLEEVLKAQKRRKARSAIRREREELWKAIVWRQRRARVRAQALCVALRTHVDKRFRLDDDLARALLTQTRLQIPRPLDMNAFQTPVEEVFARLQHLSQHTHVAFAANCFNHGSLNFNHTEMVAHGRLETVIDSRKAWVVPFAVDDVHRSLWTFMERLYLMVPEPDYQADHQSSADSVVTSYFFPAKAGDPAYQAREITKNFCLSDGSSVIVSSFQADSMDSIDPDLSIYEVLWTRVRDVSSNDDPPLTQVQVSMRTIVRSEGTETLSKGVHQLMQALESESEVSQSHLEALLLTSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CBS3</accession>
    <name>A0A8K1CBS3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CCDC113/CCDC96 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_004526</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CBS3"/>
    <dbReference type="OrthoDB" id="10254794at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051885">
        <property type="entry name" value="CC_CF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025254">
        <property type="entry name" value="CCDC113/CCDC96_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15654">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15654:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13870">
        <property type="entry name" value="CCDC113_CCDC96_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC113/CCDC96 coiled-coil" evidence="6">
        <location>
            <begin position="170"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="175"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW59457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="347" mass="40405" checksum="58AEEDAED98CDCBC" modified="2022-08-03" version="1">MPPILSQTHRVDEDGDDDHDEDDARAEALRLRAAIDEAIELRDELQQKNVRVQRRIATILQKSQEATNNGEPASQRRDDKNSANENEKRYLECLRSVHEAKVQTTTAQSQYDRIALDLQAKLDEKEAKVTEIQDSFLEFKREIAKNAENMRTGKPIPARVISQFEAAELKKDQEVEKVRLKNINLRTHLKKLEQQLHAKEQLAEGLHLIDFEQLKIENQTLNEKIEERNEELHKLRKKTTSTVQVLTHIKEKLQFILAENQLLKKESAELEEALSVNRDKLAKKKKERDANRQVLLKLKNKDGFAKSELLIEDFEKRDADLVDLERRLAELMQRHAYLTRSMSTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CC27</accession>
    <name>A0A8K1CC27_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_000300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the elicitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CC27"/>
    <dbReference type="OrthoDB" id="116756at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052040">
        <property type="term" value="P:symbiont-mediated perturbation of host programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.239.10">
        <property type="entry name" value="Elicitin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002200">
        <property type="entry name" value="Elicitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036470">
        <property type="entry name" value="Elicitin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00964">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01187">
        <property type="entry name" value="Elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48647">
        <property type="entry name" value="Fungal elicitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0928">Hypersensitive response elicitation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035477306" evidence="7">
        <location>
            <begin position="27"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW60258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="308" mass="32499" checksum="27298B2FF898BF15" modified="2022-08-03" version="1">MPRSLGLLRYLLLILVVWLYAGPVYGQDDTPAPPAPVDTPAPATTEPPAPAVSEIPAPVATPAATPPPPAASVTPAPSATTAQPASTSKTPTSTSPAAYVSTSEPYCSDSVTRSLIKLFGKNRNIFEQCTLDSQQYVFMPYNGTLPSTEQIRAMINSSACLEFWQGILSLPSFPECNLSGIDLKSAIETLVMTSQDVVNQIQPLSMTQYKDFIVWRHKRNVAKESGLKYDNTSTSALEFDTALAAAAARLEVTLTADLVIQVKGEAIGSSESILEGSLTGSAESASAPRLIGSSLLASAVVLLAIALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCD4</accession>
    <name>A0A8K1CCD4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_000798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCD4"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="633"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW60756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="667" mass="74166" checksum="5904D247F89A4048" modified="2022-08-03" version="1">MSSTESEALSNGEAVINAMAMPMGDLTAAATEFNPESMVETATSALVESAAIAALPPSTPGRHKTRSTNLTHEQKRLICLYAKQNPTFTQAQLGKWAKDHFGLPSVPSQSSISHTLKRRQNFEHMKSEDWSSKRMRTVKFPDLDTALANWFLYCQARQTRIQGDEIKAKAATFFELMYMPVTKPPQFSNGWLHSFQSRHGFSRSPSTHTTETELISTRHEFLEATKGYAPWDVYWMDETRLEYALLPEKVGHPVDNDKQLTLALCCNADGSEMLDPFFVASAPVNLTVSPPVSVDYGFTYAHNMKVWMTPTVFREWLLALDWKMHEENRSILLLLDSFSSHQVKKLTLKNVTVRFVAQTATGQSYLEPVEQTLMTAFKTRYRQYFLEYLLNQKTDGSEVSPLHAIQWVIKCWRELPKALVTKVFADIGIANDESPTSVTGDATEELEAKLREEVVALIKRLKLKTPDDLADFIYPLSERIIDEDLTDQDFVQSALDGGLSTTVEGKNVEPPRKVARIARLKKTGISAGNESAMLLMQSGSAGIQVQTVPVRSVGRMTATGDDITVPGGTVIPEEEWQAWADSHRYRIDELHALETVIRLANEMNCDTSTLVDLGRIQAELLQKRQAGERSVPAAQADAANSASGSSDNGKQSAGICRFNFGAGSTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CCE2</accession>
    <name>A0A8K1CCE2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CCE2"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01941">
        <property type="entry name" value="YeiC_kinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="8">
        <location>
            <begin position="343"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="8">
        <location>
            <begin position="565"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="709" mass="74905" checksum="5645684B68932378" modified="2022-08-03" version="1">MWRQGGSALRKRLALGDEVIEALYGKNKKPIVALESTIISHGMPFPQNVEMAKAVEDIVRAQGACPATICIADGELKVGLSDKDLRVLGEMGCAARKCSTRDIAGAIAEKIVGATTVSSTMRIAHAAGIRMFVTGGIGGVHRFAEETMDISTDLVELSRTPVAVVCAGIKSILDIPRTLEFLETHSVPVVGYQSDQFPAFFTQDSGVKAQLRRDTPQEVAALIHESIGLELPNGFVVAVPNPNPVSSELISHAIEVGLKEIQDNDIKGQAVTPYLLKRLNEITAGASLGSNIDLVKNNAKVGSQIARALFELDRENETSGVTFSIMEREASSKPQGNVQAKGNVLVVGGLVLDIISASTSPIIRATSNIGTIRQTSGGVGRNIAECLKRLGANPLLVSSIGQDASGSILLKNLEALDISAHGIQISEDVGTAVYSAVLCSSGDLDVAIADMRALDEIDTTAIPTETIKEAKVVIVDGNLSPAALHELLTRSSSIKSSVWFEPTSVQKSVRVVDAGVVPHLTYVSPNGDELAAMSAAIHRKNGEDTSAHARFKLSEGSKILPAQKMSQLKNDCLTLLLEMAKDDKETEKHVIVTLGKHGVLIASVNVDLEQTKTAVAECEFPAEVWGAHHVHGYAVAMVHLPGVEIDVVNCTGAGDSLVGGTVYGLLKGQDIYQSSHLGMAAARKSLVSQHAINPELAAEGLEEAAAKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CDP4</accession>
    <name>A0A8K1CDP4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitinyl hydrolase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CDP4"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20104">
        <property type="entry name" value="MBT_PHF20L1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF46">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUSP" evidence="2">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="1">
        <location>
            <begin position="470"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1089" mass="125134" checksum="2F99C088FCF45C09" modified="2022-08-03" version="1">MTWTRAEAEEWLREDRLREGQQWYLVAMEWWIATFTDPQSAAELDGDVPMEEASEVTTQESTESSRMGPVRNEALVDLEFSSKARKSVVLKPLLAEQRDYLVVSERVWNRLSHEFGFDWEIAREVIMMPESNKCIVKIYPVAFQLLYWRNGMQEPQEVVEGEANQPVVLVMSETESLNAVQHVIQQSLLQRLNEFFPDVKPEDVAKALQVAYRRTEQLPWVALQEALHIERNDTTKQIMVESTVVRDLDLEERAYRSGKERFHSLLIEGRFQSPEGTTDWRHDRFFSDILANMWRTELKKGQLIDALDTDKKWYESRVLDISEGKVFVHYRGWTDKWNEWIDLFSNRLAPRFSNVPNWRDFQVNDQVQVGRTQEGRAFPEWRNAFVREVEGNFEEGTLRIKVVWDGKEEWRDAQDELLCRPGTHKVTNASVSRPLGTAYSSNTPSYNRYSDRRDYSMDYGRGKPQFTGVVGLQNLGNTCFMNSMLQCLINAKPLKEYFLTNTAEGAPLFEKDVNEDNPLGMKGMIAREFAKLIKRMWGGEYTVVSPTTLKAVIGQYAPQFAGYQQQDSQEVMNFILDGLHEDLNRVRKKPYTTPVERNGRSDIEFAQEAWAQYLLRNDSVIVENFMGQLRSHVTCSNPDCANESDTFDPFMSLSVPIPADESVSVKVQLFWASGKIPTKYAVRVSKDATIGDVKEKLSALASIPASHLFFVEVRLHKIKKAHSDRSLIENIADDILHVYELEFPVSEYEMGSSNLRFIQPKPLAAQDATSNGKSMRLVALLHQAPVASPVDTRSEDYDFMDDANSGPKQRRVEVELSNTPLLVSVGTSVSKAEIHKSVWQAVRRLVSDETSFDCGEEAALPYRLHITQQNGSSALQRDVPYADEPADLPETSSQDYCFTLEWSRQGYQRGYDEKSAKRIELHESMRQLKITQPENVTLLNCLSKFTEREQLGKTDTWYCPKCKDHVRAFKKFDLFTLPRVLIFQLKRFRYAQSSFYMHRDKISTLVTFPIELLDLSEYVVGPKPDGGLIYDLFAVSEHSGGLGGGHYTAVAKNPDLGKWFSFNDSFTKEANPEDAITSRAYVLFYLRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CE55</accession>
    <name>A0A8K1CE55_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Intraflagellar transport protein 74 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CE55"/>
    <dbReference type="OrthoDB" id="444379at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029602">
        <property type="entry name" value="IFT74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="506"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW61353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="71160" checksum="A0CC77D71F3EEA12" modified="2022-08-03" version="1">MSGRPGTSSGQRPGTGSGARPGTGQSLNPIVRPGTGQRSSLGSSAGRPLTGRLGTGQAVPATPGQTAGFGISLNTEVNVSDRPVTQQGMMGMRVGTAGPGRQVQDASFFMGKLHAKTSEITTEIEKLRKEIEQDAKDKSQYAQLERKYETLAIEVRDLEGQLADYNLAMDKLRSATDPQEIRQVQEQLRNRNAKEAEEVDRIFILRQEQETAVRRMEHEVNDIHMKHQDKINQLAPQKLQRYKEMLEEHHQTEMEIEARTQELEMLMHTIHQKEAELSSDRYREEYELLEKQARKLQKEREVMQEEARTAMMDPNEARAVLLAKVKDDKAKMETMEKVLQVAHDENQELRKTLNEIKSELDERTNGNAKDDPAQKYEMLFQRDKEMTAFLESFPGKKEEELKAQRETQLMIIKLLEHISSNMAKEDKLLPGANAANLEEMKSDLTFKERQLESSVTTKQRLTMELQKRQAELDKVNTLDTKISLELSSLLQKMDTMTSDMNEFGKIDELKETHQQTKQYLQRMKQQYIRRRDAMKQQVTALGIQLENLKQETANHDTAKNLDALEQKLRHHEQNIFHLKEYIDSKSREINYEHVKQDCLKTLQELNALRIKQQSLLNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CEZ8</accession>
    <name>A0A8K1CEZ8_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_009737</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CEZ8"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000589">
        <property type="entry name" value="HSF-type DNA-binding, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW62244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="263" mass="30085" checksum="82D5E0752023CF5D" modified="2022-08-03" version="1">MTDKTQRKRSADGELTIARAGLAASTTSAPVFLQKTYDMIESSPDHIAAWSETGTSFIIKQPREFAKMMLPRYFKHNNFSSFVRQLNFYGFRKHKKDEIVINTVNDETRNWWEFYHEKFVRGKQELMAQIRRKTYSEPTSPDKEEVETLKNSVQDLQHQVSDLMDQLGDLTSLVKTLLQEKLAANNASSEPAAKRVKAAPMPQLPAPPSALFPPTSYQQIDSAKKPNDLSLLEWTEAYGMDYFTNDTRATVNLFGDEDVLNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CF50</accession>
    <name>A0A8K1CF50_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000075">
        <property type="protein sequence ID" value="TMW61878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CF50"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW61878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="177" mass="19689" checksum="933537DA67394CCA" modified="2022-08-03" version="1">MEKDITLGCVNVQDGKVFGVHMALDAYIFDLKKEINDKKMYTRDPDDLTLYLAKPKERSQWLAVGGPAVRNLRSNVVSDEIQQLLCDELLPTDTIEDIFKQAPTKGVVHVLVVPPEPPAPPVEDEFDLGVDSAHTAAWAPYVDAAKLLADDPQVLRLVDELKRVTTIEPTPFVVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGB5</accession>
    <name>A0A8K1CGB5_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysophospholipid acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_005627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW63009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGB5"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="54981" checksum="AE0F613CC7B73A3B" modified="2022-08-03" version="1">MNATTDMAQLVHTMEQYGTLATPLEFNYFNQELGKLSGSIGFPLDQLRFAICLFLAYPLAWFQRQLHAPVAKHSLNILVGVAMAQFVYASGWLHSFVSAGITYAIVKYAPVRPMPYIVFAFNMFYVAGLHIYRMSVDYMGWSMDSTASQMLLLIKLTGFAFNYYDGIVTESTQIKSTDSPTKIKIKQSRQALSITLLPSLLQFYGYVYCFTTFLAGPAFEYREYSDAIDGIKFFHKGQRRHVSPAKAVATKFSIGVFFMAIVASFGSFANLRVILQANDPLLVKLVRVYVALFVTRSKYYFAWKLTEGATILSGVGFEGFDVNGNPKGWNGVSNVDILGFELAGSVRELSRAWNKGTQTWLERYVYNRTGNSLVATYLCSAVWHGFYPGYYLFFLSVPLATSVNRLARRHVRPYFLRIDGSDAPAKPLYDLASWVATAITINYLAVSFVVLSWTDAINGFHSMHYAGHVGLLLGYLLLSTVPVKKITKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CGZ1</accession>
    <name>A0A8K1CGZ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW61962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CGZ1"/>
    <dbReference type="OrthoDB" id="79283at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW61962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="226" mass="25145" checksum="9A2E0D08F820D203" modified="2022-08-03" version="1">MKAGSGSDSGVEAFARFGGFFLVKGPTEARHVRYAMDVAIPPLQLELRCIQRFSTYYVLRKRLIKATSSCQGHGTSHSGAVADLDLHQLLGPRCKGCRLVRKTLKSIPFPRRSMFKATADDVENRAMVLEAFLHTCTRLLITWKGCERGRKLFCVVLGKFLGVNLLQLMNHRLRAMTTLTSLDVDSESFLTQMDPQVDPIDGEQSIVTSGIESELDSEISYQVCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHF2</accession>
    <name>A0A8K1CHF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Poli38472_005161</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHF2"/>
    <dbReference type="OrthoDB" id="268799at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000044">
        <property type="entry name" value="Probable U6 snRNA-associated Sm-like protein LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="14">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TMW62543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="88" mass="9655" checksum="9CCF1BFEF6433873" modified="2022-08-03" version="1">MADEQVTKKTPADFLKSVLGRPVDVKLNNGVEYKGVLACLDGFMNIAMEQTHEYVNGQLKAQYGDCFIRGNNGACLRPDTVLYIAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CHQ1</accession>
    <name>A0A8K1CHQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase epsilon subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_002200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in DNA repair and in chromosomal DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CHQ1"/>
    <dbReference type="OrthoDB" id="10254730at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="273"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW63259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="534" mass="59661" checksum="FCB1D8A027D37C61" modified="2022-08-03" version="1">MAAKQVLRACKLQGLSLHPDALRRLVDELTAEPTLELDNVVYALKNSIDRSKMTSSVVSLEALESALDTLLAVSEENQFESIQIFDAFTTPRLAYNSANSLYELKADRHRSIHAPAESRLQLLRDRFQLIDLRVKRNKMFAPPAISVSNEVDYIELSKIESLLGVTGIRRVIGMLGQDERKRYYLEDLTSRIYIELNNATYTNGLFTLNCVVLVEGEVIDDLLHVHTMGFPPPESKAESKVILGGVDPLGVEVSAQQLEQIQALEASDHHATFIVLSDVHLDDPQVMQHLDLLFQGLESVLPSLFILMGDFLSTPVGVGAGSNTLEDLKDYLDELGNLILKYPKLAEFSKFVLVPGPNDPGSSRAFPRHPLPSLCTRDLVRKVPNVICTTNPCRIRYYTQDLVIFREDLHQKMHRHAILPVLPDEVTEANGDAMDVDSGNTHAHVDISKHLVKTIIDQSHLCPMPLMAAPINWAFDSAMQLFPLPDVLILGDSTEQYQLGYSSVAVFHPGPFHVDFSFVLYRPSTNTTEFSRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI39</accession>
    <name>A0A8K1CI39_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_005506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000073">
        <property type="protein sequence ID" value="TMW62888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI39"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW62888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="316" mass="35948" checksum="FB2D855B3E2EFE22" modified="2022-08-03" version="1">MGVTTALDIASPDDLNTLHMVRDALQNATTQNPLLHRSHFMVIVKTAKDWSLDSLCDHVKRVVQHLQIDKLDVLLLSRDSMPPRQNVYERKRVVSAYWECMVQVQRLGLAREIGVSDLLMDEMELIGIAFPANPPAVLGISIEIATDKSHEARTTLRDMLSFAHGRSMDVLVRFPIRGLDRPTEAWEEVRFRIAQRLRATVFDASIVNEAEAEPYYTERHDMTESETLQTSLQIIVRYFIQQGVVVIPVLDGEDDNHFTEDEAHQLFTVLPHPFTGLEPSYSPQTQYSSILTRDELVEIDRVLPLVVTESQADCTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CI67</accession>
    <name>A0A8K1CI67_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutaminase</fullName>
            <ecNumber evidence="2">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_002803</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CI67"/>
    <dbReference type="OrthoDB" id="2039at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903600">
        <property type="term" value="C:glutaminase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008614">
        <property type="term" value="P:pyridoxine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000041">
        <property type="entry name" value="Glutamine amidotransferase subunit pdxT, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="59"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="151"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW63862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="24089" checksum="665BFD8212D920C0" modified="2022-08-03" version="1">MKTINVGVLALQGAFQEHIDMLHKLQLTDASGQRVVVRAFAIRLPEQIQDADALVLPGGESTTIGKVATRWGLLEPLREWVANKRPIWGTCAGMIMLAQSAKHAESGGQTLIGGMDVQVSRNFFGSQVRSFEMKVDGPPGFNSEPYNAVFIRAPAIISVGETIQVLSRIDCAQPADGSDPTDVIIAAEKDNILVSAFHPELTDDTRWHQYFVERVVLPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIC3</accession>
    <name>A0A8K1CIC3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_014642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000042">
        <property type="protein sequence ID" value="TMW63937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIC3"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="31"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW63937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="393" mass="42496" checksum="421B153FFBD17182" modified="2022-08-03" version="1">MLRRALLTRPGLSIRRASPSVVLMSSSTDSLRQEFERKLALGKQLPPLEDNASKLEMYALFKQANAGKNTTSKPGMLDFVGKAKWEAWSKLGDMSQEDAMTKYIAIIDNLAKANGVDPANPDAASATPAASVSSSEDLLVSTSDDGLLTLQFNRPARHNAINREMYNAIIDALETSASQSHIKAVLLASKGATFSSGNDLSMFTPATQGQSFEEMAEEGAKLLERFVNAFLTYPKPIVAAVQGPAVGIAVTTLALCDLVYVSDTATFHTPFTALGQSPEACSSILFPRIMGNARANAMLLLGEKMSAQDAVQSGFCTAAFGVADFDKQVQEKVALLLSRYPNSMKQSKALIRSPAVLAELQEVNRRECETLKKLWLSAECMDAVLKFQARKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIY4</accession>
    <name>A0A8K1CIY4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIY4"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW64297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="143" mass="16849" checksum="0ABD600ACA221350" modified="2022-08-03" version="1">MFNFVALAEENHKWLNESTIQLVNESLAMKREEFSTHVASGRYWNMTEQEKMIVSPEIRRIEWFPIDQAIAMMESSLLDPYTPIDEWQRRQFHEYGVERRDPMFVTMKILQHIAAFESPEALLAHTKQLTAPLLESLHQSSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CIZ3</accession>
    <name>A0A8K1CIZ3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CIZ3"/>
    <dbReference type="OrthoDB" id="166868at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="249"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="60790" checksum="BA5A16816D0C9219" modified="2022-08-03" version="1">MAETAPKKVWSWELVETLDSAFNFDEFRREEFCCSSILTTDNKKYACRLCPSSVVDAHNMVERRLECVSPACGGKKSGCPVMWRVFSCEKASVWKVYDSAEEHKRDVDSGCGGTHNPRITDEMKDYIMEQDDANQTPRMIHVNMQESSAITWKPETWPSLSQVQNCVKYLKRRYGTKNSIRAVRKMVREHHYHADVEENTPLIFGAEDDEEGCARVGEGDGKDPFLLGVTTPALVNASIKFANKGPDAVFHMDATYKLSDLGYRTVTCGFTDAARSYQLAAIIVISTQTADDYESCLKALVKIFKRVQPGVSLKILRFMGDGDHAHFNAMKKVPEFSSASYLMCFFHVLYNVRKKTRHLTDVLRRIIMDGIVEMHYAASESEYEELKQSVLVWWWSFSPLRDFVRYFQKQWLEGKFNRWQIWHTSYGLPTTNNPCETFNATLKVYSGRRRQHMQRLLEMFFKVVKHAKKLEPTKPAESVPPSRELKKAAKSLLDSGKLVVYVSRTTNGDVDGEIVLVISLMPKAPKGRRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJ15</accession>
    <name>A0A8K1CJ15_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_002294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJ15"/>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW63353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38188" checksum="6175F06CB8D6A142" modified="2022-08-03" version="1">MAHKTPAPEPIGVLRGHGAPVNAVSALSSTTVVSGGADGVVKLWSLRTRRESASIQAHSKAGILHVTRFNDGSRVITHGRDGYISLWDTGALGRKDAQPLMKWYCGSFTFTKAATMRWSEDDSQSEFASMIVSPSSEEKDIVLYDARQDSSKVAMKFQVDDTDKKHGMCMSLSLFEATTSSQDGARHPFIAVGWEGGQLSLLDPRAGGKVAVEAQVANTTEPLLAFDVTHDGRSAICGSAADDLSMVSMDLSSLTMEVKPFFKCNHGGISAIRLRSDERIFATAGWDHRVRIFHRRTLKPLAILKYHTESVFGVDFTPDNQWLLSASKDQKLALWSIYPPSEAKQKGKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJB6</accession>
    <name>A0A8K1CJB6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_014216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000041">
        <property type="protein sequence ID" value="TMW64099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJB6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="343" mass="39540" checksum="6EFD00DC1C4823FA" modified="2022-08-03" version="1">MDTSEDERKRRKRKKYTPTHRARKVEISSLQDQIQELTTRLAQLQAEQPPTADDVQRVLEKRTILQSGLRASDLVLARTHSILQGQVAAHQRNPLERVIRLSADPIDRQRTLDDHFAKALDSATEFALERVRYLDCEQCHTHSRSFSTPEGDSVLIQCEVRAVLGVESVRQAYESVHLALLHREFQFSERLGVTTICDTDGIQDRPASLARYLSTIADSVDIEVNMAQFHRYVESSPYLDAPQGVIVVESVDEDVLYPYQPETRVRADISAVVLVFERPRAHSHVPDSIDVTVIRWSFTRLRHPQFPVPPEKKQELIDVYPRWGETLSKIIREYVDARRRCQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CJF2</accession>
    <name>A0A8K1CJF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_002741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CJF2"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW63800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="36339" checksum="752A4FA507A54E31" modified="2022-08-03" version="1">MAAAIIDWQLAYAHVETAVRESVSEFPLPYATAGALAVNLQLLWVITFGTWLASVLTLNYSHVDRLWSITPFLYVWYFVYRAYLDDGAQWNDRLVLMGVLATAWGLRLTYNFARKGGYSLNDEDYRWGVLRSKMHPILFQLFNITFIAFYQHLLLFLIVFPAYVAYVYRLTPLNDLDYVAAGLFLAFLTLETIADQQQWTYYQTKYALLAKKATLTGDYKVGFNRSGLFAYSRHPNFFAEQSIWCAFYVFSVASSSVTWNPSVIGAVLLILLFQGSTQFTEYITLGKYPEYKTYQQQVSRLVPWFPAKVAKKHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CK60</accession>
    <name>A0A8K1CK60_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_012833</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CK60"/>
    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000005">
        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000002">
        <property type="entry name" value="Molecular chaperone DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008035">
        <property type="entry name" value="PRK10767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="200"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="200"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW64211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="461" mass="50630" checksum="897E46E5D24B2CFE" modified="2022-08-03" version="1">MQRSARQLYVRVAQKKPLLRNAVLVRGLKTPAYATRATSTRVFATPELLNGQQKAGFHATPVSNQQKRDYYDVLGVSRDADKNEIKKKYYQLAKKYHPDTNKEDPDAAKKFAEATEAWEVLGNEEKRQKYDTFGHAGVDENGGYGDASDFQGFEDIFGGFASMFGEQAFGGRGRRGANQPQRGADIQVNVNLNFMEAVNGTTRDLHITANEECGTCNGSGAKPGTKKQTCRQCNGSGVEIMQQGFFAVETPCRRCRGSGSIIESPCGTCRGKGQVKKPRTVEVKIPEGVDQGMNLRLAHQGEPGVNGGPSGHLYVGINVQPDPFFKRRKTDVYIDVPISIAQAVLGGHVVVPTLSGEVELKIPKGTQPDTVLQMRGKGIKELNSSRRGSQMVNLQVQVPKALSPRQQELMEEFLKEEQELKEQGSSNCKSHTFGQTVHDTVDRIKQFLKGKTNTSEDSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CKI1</accession>
    <name>A0A8K1CKI1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Receptor expression-enhancing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_011624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CKI1"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW64744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21376" checksum="AA63C0C802F5A1A7" modified="2022-08-03" version="1">MDKVQVYLDKWSKDLDKIPVLQKAQDATGVEKLYLVAGGSAVLLLLLLIGFGAGLICNIVGFVYPAYESFKAVESDCKKDDVQWLTYWVVYACFSIIEVFADFLLYWIPFYYAFKLGFLLWLFMPSTQGASFLYTHFLAPFLKNHEVRIDLAMKDAVNSSGAVISDISGVVKDVGRDVTKAVAAKIVDGSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CL09</accession>
    <name>A0A8K1CL09_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein acetyllysine N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Poli38472_012920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the sirtuin family. Class IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CL09"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF12">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TMW64298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="350" mass="38802" checksum="532CBE7E08582404" modified="2022-08-03" version="1">MESDGQHAPTSPPEGADGVFDCKTMGIELKNDSPTQDYPAQGANEAPMSELITDESELDRKCRRLAELIAKSKHLVAFTGAGISTSVGLPDYRGESGIRTKNFDRKKRRKTDGVDEKGIVIPDFNALVPSPTHMALYELYRLGYLKHVVSQNVDNLHLKSGLPADALTEVHGNATQAKCETCEKIYTKDFPWTGLCDDAACPSTKRPVEQRLRARTRHGNGRLKRNVISFDEPLDDIDNAIDECEASDVALVLGTSLRVEPFTVMAGEYAESLIIVNLLQTTPKLDRRAEVTGVRLYEKCDVVMEKTMKYLLGDSYNVPQWQGEHPTEVFVPEHEDKNLVNVLAGRLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CLA7</accession>
    <name>A0A8K1CLA7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubby C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TUB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000040">
        <property type="protein sequence ID" value="TMW64433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CLA7"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.90.10">
        <property type="entry name" value="Tubby Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000007">
        <property type="entry name" value="Tubby_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517:SF7">
        <property type="entry name" value="PROTEIN KING TUBBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517">
        <property type="entry name" value="TUBBY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01167">
        <property type="entry name" value="Tub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01573">
        <property type="entry name" value="SUPERTUBBY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubby C-terminal" evidence="3">
        <location>
            <begin position="165"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW64433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="430" mass="48489" checksum="4D20AE6C7DE57E4E" modified="2022-08-03" version="1">MTGRRDPTSTYDRMMAEVQMDSDEEVDSKKQPSSRMSESKHSSRSTASKNESTRDDQSKKSTKTREMDAKQSDDQAQPSDSSQPKRRSSSFPPSQRPQTHRGSKSRNSDGEDQSDSDHEQEAPVRHREADPEFTTPVAPVSAPTCQQSECESIRALLTRAPRHGSPPIRCYVERDRHGLHMLHPVYRLFLEDTKQFLLCAQKRSTSKTSNYLLTMEKNPTDRRSPLIVGKLRANWSGSEYIVYNDGISPDRTALESNVREIFGFIEFAYDEMGPGRMNVRVPAVQENGLASKWKDPDLDKDSPARQSFLTHVDKTALLVRNKRPQFDATTGGHVLDFKGRVTMPSIKNFQMQSDVHGDDTVLQFGRVSCQPPGPRAQCKCHKHTFVMDVQHPLNLVQAFAICLATLDTKVADAKMYESVAKLVKKKSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMA6</accession>
    <name>A0A8K1CMA6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMA6"/>
    <dbReference type="OrthoDB" id="157635at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007021">
        <property type="entry name" value="DUF659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04937">
        <property type="entry name" value="DUF659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUF659" evidence="7">
        <location>
            <begin position="244"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="8">
        <location>
            <begin position="655"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW65523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="757" mass="85999" checksum="51746BB10F0B87B0" modified="2022-08-03" version="1">MATPTNALSNMLPVPTLSHDGSLGDPTQPLKKKKPGRSPSQIWLLLTDEPNPQRKNAAACKHCKQQVLYYKKSEQAIRHLKKCSVFQSNQHQYSFIAQFQDILPLYQQKISQKATSKKRQKAQAAAAAAAAAAANGVNPNVLDPQTAAHHHASAMNSLAMQQGMPDTLMDPTGMGLKDDSKEKTPLRDRKSKSSGGGTLSKVQQERMEEALAMHAYVTGMAFDAIEETHLQRAMAILRSNVKLPDKKRLESDLLLRCYDKMHKRVWGYLTASSTRVCIKRDAWSNMNLYNTSNPEDVYVTYMAVNSEKRFFLESEKVSDDAQFNSILIAQDIKRVMAPIVNSVSGVVTGSTEYHARAWEMLKAEYPTKFFYGCITHALHLAIMDIFGPEKSLENDPRRMTPQLPMDFPFQDLVDFTNNCNELISFFSSYQYAPKFKMFDSQTLQTMKSFSNASPTMQWGTLAARFRVLLQSEDIIQSILSDPEFITAAPPNQRGTRQSLKDFVMSLNWKMLEKAISILTPIELILYKFQDDKAPISEVYFESKHLLTDFDAVFGLSTVELEYIKKVVTERWQYVLGEAHGLAFLLDPRYIGKSMTREYREQIEELIFNFPETDADMGINEERKRAISAEYTDYVIYAKNQRANGTFKWEMLEKGTRTPLQFWQTEADEWPHLKQLALTLFSLAPSSVASEKSLCKASLVQSSRRNKLSFDDMRRLAFITINDSQFTTNRVGDFQNALPDFNMGDAGLSPEGMMMWMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMB0</accession>
    <name>A0A8K1CMB0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_009407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000038">
        <property type="protein sequence ID" value="TMW65240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMB0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="256" mass="28540" checksum="E843696CC1B837F6" modified="2022-08-03" version="1">METATAMEETSTGTNRLLEFGVDDMISLISGHRQVESVHLEVVKLIFIFAHIKVAQSPLPFDASKSSVFPDRAELATPWIKIRLTMSDFLGGTFAGRFLRESTQRKELARFIGRDDVRVERLLLGSDCERLPFPLGGLEPFALVGTRCAWGGKCLVGIVRVIKPTKKTLLPEKWAFSASLHVAIADLNAGNPVFGVVTDLEAFWGFQWIGSENSLYYSSPVTRVAAYTLMNQFLDGCLGWERHSPLQNKKLLKHMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMB2</accession>
    <name>A0A8K1CMB2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_004026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMB2"/>
    <dbReference type="OrthoDB" id="58859at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37066:SF1">
        <property type="entry name" value="LNS2_PITP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW66261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="63598" checksum="6B90CB752999161F" modified="2022-08-03" version="1">MWLRRATQCALGGVTRSRPRCGWPVNGLLINSLRPQSTSLSQRFYGVRSSTESRLRGRKRSSPHTSNASQAKRSEELARIVQAMRIFYEREQHFAVPIGFEIPRASPHYPSELRGFPLGVKIHKLMQLVANDKPPKGSREHITALAESGFPVESWRDYLFDTVFVPALRSYYSQEGDLFVPQKFVVPVDPSEAQWTRPTWGYPLGLQVAKLRREPYMLSPEQVEMLNAMGFVWNVREAKWHQYFLPGLRLFKELHGHADVPLAFEIPDEDAWPKYLRGYRLGRHVYMVRSGKYAEWVEESKGELEMLGFAFDLSDSLWNYTIFPALEMFAHLHGHCDVPQDFVVPAEDPWPETAYGWRLGHTVKSIRHQGVYKAQVQAARVDLERIGFVWNASDRLEVTLRRIVLPAMKTYQNLNGNLLIGTDFVIPEHDGRWPEQARGFRLGHWITRVRGGQIELPRAFRDELDQLGFVWRFNDERWHEILLPAFRVYAELHGSCKGMSTKYVVPHETPYPRRAWGVNLGGAMWHIKNGDTYMHDPVKERELRKLGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMF2</accession>
    <name>A0A8K1CMF2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMF2"/>
    <dbReference type="OrthoDB" id="121053at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="56638" checksum="A83406D1794A1301" modified="2022-08-03" version="1">MAVILLTPLPTYVVLLLMDGVPMRDPHDGVRANGVALTRSGFSHFVMTLAVLMAVKQAVFRTCQSYSMRGMVQMSLWAVCVLESTGICTAFLWRYPIPFREIIFVPLWTALVIGANWYFAKEAILSRAQAMIRYIPLISTQFVFFYGLLVLALAYSIFSMTVQIILTALFPLVRIICRRSIWRQARNSDDISTDLTMCLLEITAALYQTISLQFAKTPVLTVVIMVSDLIPTMIEVREYLGLEYLVDSTSTLSTVVKIIKSGMSSGLTERHSITVPIPLGPSASKYLKDSALLFSSESSIASVYVQRDHIRKANSRRLLDLKQFEDKSEHSDTGESGCARVERCLSTPNFPTAASPSPAIGDLHPSQPMTIEGQASRRTSLQGITFEYGNMDSPSRRTSLSSLRLPPIQQKRMSGGSVGRHQIHPIGGNEETSGIPDQAAVALLSPSKTLATSEPSGRRRSTGVMIDGVAISRKDQARILEQTLQLLFSCEVLLVSEYFEVMIPFYMRSCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMK2</accession>
    <name>A0A8K1CMK2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_004161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMK2"/>
    <dbReference type="OrthoDB" id="70673at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW66396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33027" checksum="6458C925DF58CB81" modified="2022-08-03" version="1">MREEGGDVLVNIGKVLLLLVNMAFMVAGCLLVYFSQRVKSVGWVEVFEGDFQWVGDSAFLFMLVAGAVVISLAAIGCLGAWLRNRMLLLVYSIVLVITAGLFIVVAIGGHSAKSTAQEWKDASYPANDKEPSVGQNFNKLYCYSQMTYYCAANAAEVVKLLGMTSTSSLLSTFTVQDICASSYKPSDLDQLCELCAVLDKYDDYKPVQEWTDTSCPRTAANQAWCGAFFVSGEPGEVFANASPYSGCRSALFDLILKYSNMLFFAGIVVCLATVLMLAFACLLRRSANRPYVDDSFVVDTPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CMQ7</accession>
    <name>A0A8K1CMQ7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_003925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CMQ7"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="278"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW66160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="730" mass="82667" checksum="AACD69F1233FE333" modified="2022-08-03" version="1">MQVASPDEYLELMHHRAMHQVNQVLNVCLHSPRTEEKWTCLKREKRMELYAKKSNTTRSVFFLGVNEIQCRFDEMYELLNYRSTPAFRQFMRQVYGRNFRDGAVMSTHEPREYDEDYDVADVRHSAVWFSLQARRDSMLRNDNMLTFFQALMILHPDRGSTAASTMTAHVRPSECIKKRTLALTWLPFYQTEELAHVQDSLRLQYTLIVEEVGRQRLHLSCVATSFRDGDDFQPRSHGAARQVAQRLVKRSVTKLENAIMAARIHRQELMSPLEWVRNEERDACVVCWKQFKSLYRRRHHCRFCGEVICGSCSSFREITDLHHRGGFTKVRICHLCNNPRRLRNESFVSSPAASLPQRQVGEDSRISSTQAYFPNTTGLPPPHRQRRRPPTETTNDLPPRQRGEDDAQKKKKVTVYDADEDDYVDGELLEMSDGYMGNFFVLPNGYSSNQKIISIRSLTPSEILGRSSSSSSTTASCATIPTNSWRVPMSVSTNTIQNTLSPAMAMMAMYARRTAEANWRAESYSLSFLHPAALQPDRVNVPAKSIVADIGSNERATFLSDSKKPSSNGSSDVPRRTSITSLGMFEVLDGTDCASSVDARGSTFCGPPLAPRLDPESEMRRLKLMQVICSPACTLVERALMHACCVQVVSAFGVMGAFIARVEETDVVIEHVIGTREIVACDQYLRSDTLCDHVLVATGCPPLCVVDCMSDARTREMAMVQDLRISLFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNH3</accession>
    <name>A0A8K1CNH3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_012007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNH3"/>
    <dbReference type="OrthoDB" id="275371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW66891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25730" checksum="65395245A82B4274" modified="2022-08-03" version="1">MTSMAMRLRRSTRCGGHAVAVRRLSTAAASSRRRHWLEADCGDVPTQPRPQDLDISEMLRGGHALQVANQKMIGAKLASALRGPATSFSDAHTQTLQELKDLEDRNVERILESAETKGLRFRPSLLIPAVRCSSVTLGTVLSLFGENISRSYISGVKIAIADYYNDQIREIYAHKQEETGLKELFKATRDAELEFVETHSPEAFDPTKEDTDAVRTFATNSTKVLLQVAKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNR0</accession>
    <name>A0A8K1CNR0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_003740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW65975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNR0"/>
    <dbReference type="OrthoDB" id="114182at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="159" mass="18140" checksum="2E1CF3346D154070" modified="2022-08-03" version="1">MFVYERRSWQMQVYKAVFRETPSTCATSIDRGELFGGPEFIDLVVHNDDILARWGTVITYEGRDLSKHVTRFLSGGRYAPLHLTDFSVVDVRRVKTEDLQKAEVEASGLTADVHLSPAVFVVWYDVGVTSVLVWNVRWPQAMRVAVAPSVDMEHHYQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CNV6</accession>
    <name>A0A8K1CNV6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Poli38472_004098</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CNV6"/>
    <dbReference type="OrthoDB" id="10261375at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17959">
        <property type="entry name" value="DEADc_DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012541">
        <property type="entry name" value="DBP10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033517">
        <property type="entry name" value="DDX54/DBP10_DEAD-box_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08147">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01123">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="65"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="269"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="555"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="641"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="755"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="833"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TMW66333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="871" mass="97334" checksum="529B9E1DA240E9E4" modified="2022-08-03" version="1">MAADDLLKGGKGGNASSGGATTHGKSNGKGAGVGGFQHLGLSPQIFRGVMAMGYKVPTPIQRKTLPIVLSGKDVVAMARTGSGKTAAFLIPMLEKLKEHSKKIGVRAVVLSPTRELAVQTLRFAKSLAKFTSIKISLIVGGEGMEAQFEAIAANPDVIVATPGRLMHHLQEIPDFNLKVVEYVVFDEADRIFEMGFAEQLQEILKNMPASRQTLLFSATLPKALVQFARAGLNDPELIRLDVENKISENLKMTFLTVRTADKPALFLYMVREFIPKDDQTIVFAATRHHVEFLHEFLKAHHIDSSLVYGEMDQASRKINIGKFRAKKTNLLIVTDVAARGIDIPLLNNVFNYSFPPTAKLFVHRVGRAARAGRSGTAFNFVDPDETPYMVDLHLYIGRRLEDSSPVNAKAYSLSTMQVSDIHYGSFPNELIDQETEHTHDILAHNPQIAPLVKVCANAYKMYTRTRADPSKLSIRRAKELHVTKVHPFFLAEYVQDESKIEKVQYIESLQNFRPQQTIFEVATGTHSVKKTSPGVVMMQVKRKIHERIIQKELAKAKETDDGLAPVDENEEEDGDKPTARTENDDAAGDMEVEDDEPVVVAPPAKKKTVFLSKFERKQLKKRVGAGEKEEDVMKELIAAKEAKAGGEIGEKGEDDEEEENEGDSGKFKDRDNYIGYMKEGEYMTEEFLAKGADGGKVNSFQEARLEEAILDVNPDEAVEMNKKRRILHWDTRKKKFVKTSVGDLTSSGTLKRRNESGAIVKKKHQQGELYKKWQQKNHKRVFTGGEEDDDESGKKLDYRRGKKPHMSNKSSVNRHAKDELLSESKIRKEEKRKARSRGVKITSKPKTKRGKGNIRGKTHGAPTRSKAIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CP56</accession>
    <name>A0A8K1CP56_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_012041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CP56"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="3">
        <location>
            <begin position="226"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW66925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33014" checksum="205B1EE390F7BDC5" modified="2022-08-03" version="1">MQHCDFLVPSQALGFYYEEVYNQWMNEMTPLMQQVPYMVLPGNHEAECHSPACLLSTFKKDHLGNYTAFNSRFRMPSAESKGVKSMWYSFDYASVHFTSLSSETDYPDAPSNSYTLTHKNGGFGNQVAWLEEDLKKAAANRANVPWIVVTMHRPIYHLEQVDANGAPTDYSKNLQSAFEELFLKYNVDIVISGHRHRYERQMPIARNAAKTDGVSSDKKTYTNPKAPVYLVSGGAGNIEANELNNNKASWHVVQSKDYGIMNVHVGPKSMQWTYINSDSKKVVDQFTITKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CQ84</accession>
    <name>A0A8K1CQ84_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_011145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CQ84"/>
    <dbReference type="OrthoDB" id="167011at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035467077" evidence="2">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW67525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="270" mass="29126" checksum="6FAF1C1D6D3CEA22" modified="2022-08-03" version="1">MKTCVFLAIAATLAVAVSAANVNIRGAQRDEAPASTDIRIRTTDVLNRSTGLLNKNRVAMDNNVNIARSNVLFSQNDRLAMAKQVEQALNAEEQDGTAVTLTRSVMRSVSAPDTDSSLMTKASAVVAAKGGDASTLSQRIADFVNAVDDKKEQSIQSETPRGMQLSVGTKDILRQPTAVINKNVGMSDNQITMSRTTFAPLRNDRVTMSNNAKVANAVVPGSAIRVDQITAREGQDQDDASSEEMRVPDDKKEQFGWGWGFPGYGWGGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRB6</accession>
    <name>A0A8K1CRB6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRB6"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35560">
        <property type="entry name" value="BLL0132 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35560:SF3">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035421091" evidence="1">
        <location>
            <begin position="23"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="338" mass="35917" checksum="2822C25E91DB27B1" modified="2022-08-03" version="1">MTLTLLKAIFLGLVAFLATTEGGLTSTVYKNFALSNGKTFNYYISYNATIPASSYKHLVLVVHGQPRDVRSTMAGPIETRFAAEKTTGALIVGPLFQVAADANANCNADSRPIPPATANDATWTCSSWMQGRESTNNGPSSFVALNNLLSKLKQDFPSLSTASLVGFSAGGQFMQRYIAFSKIPSGVTAKFLVASPSSYLYFDSVRPSPVGKDWSACTTNDACSFSFATPTNCATSNQWKYGLDARPASVAGEAATLRSNYVSANIIYVAGSQDTGSADDGCAAVVQGSGRLQRALAYAAYDRKYLATSKNRKVVTPDCGHDVYCVTKSTSVSQVYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRB8</accession>
    <name>A0A8K1CRB8_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_011183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRB8"/>
    <dbReference type="OrthoDB" id="93140at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW67563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="973" mass="108715" checksum="A08DC49FE23F35C1" modified="2022-08-03" version="1">MLSQATMIDDFCTFFGMEGVAPDDRRVMWRQIAYALFCDASRSAISSLTFECESITLEDIAAMEEVFDGRWQPDDGAVTPTDIDTATAESAQHVCVTNDAMVRVDGALVSLAILGLSSRDELVVVDDDTGTEWMEVKASSIGRLYIQCEDIVDAGVISDRVLIQQSSRLRSLMLICDRFEPGAAASFIKLVGRGLTTLRIPCKTRRWITASDTKQILQSCPNLQFLGVEHADLKSINVFIEAYEHGWCTLRALSLWDVRVANESLVTFAEKLKDPHHPMTRCLTEFRFIFDEVANSNSYGDCEVKCSAVIGVDHGQRSVIKKHTGLRTLTMEISTLPTEDGVIGSDAMTATIDARWRILEPFARAFRVPLTLEDRVIEGSLQCYCAGVSVTVPAGSSTRDMQRTRNFVDLLHVLWTLDRDAWKRLLRDGADIPFTGSMRLLPADETPYFALRVSFSKATFHQQLTSCIDFIRSPSLSAKAAQAKQDLLSAYNQADMKHFQSELRPLRVRLQFQIHGADLSSGDVDAFLIAVVNTIEDIKTHLDRSEGAHDTPTSLTSVVLDATDLDLSSQEVTADRARLLMRLESFGIPFHNVKLRLNRGSSQVDDVEEEPHSVAHVDRLLSAVLPARWSRDSTEETSPWRTQTLSVDQADLTEFASLCSTVSRTQHVKNLQLRSVFLFDSPFERYLKWQWLVQALSGSSSSIKHVAINETELELSDAVAVASILEDGMHMSEEGGIETLALSTEAANEETISTILALLRQLHHSLTSLSVYVWMNTLSSPFVSDILSICQNLRFLDLSSVELESFDLFVDAYDAGTCHIQSLALHSVRVENTKLAEFVRALADVNSRPAQVLRELCLDSVGTEGELVETNLEELLQMLNVNPWLQYLEVHVDDELHPTFVDRFEAHDEKWLPVAAERLSIESKLAFLSTVQSTKFQRTQTQSVMARLDDRVLTLVLEYAATAAQRHVYLEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRF7</accession>
    <name>A0A8K1CRF7_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_007901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRF7"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08602">
        <property type="entry name" value="GDPD_ScGlpQ1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620:SF7">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035449318" description="glycerophosphodiester phosphodiesterase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="8">
        <location>
            <begin position="42"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW68229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="392" mass="43470" checksum="1C17121F9790F18C" modified="2022-08-03" version="1">MAKVWYTSALVMALAATASAQHKLCGEGPKPTSKPTPGKTRPLVVGHRGAPGYLPDHTIEGYTLAIETGVDYIEPDLVSTKDGFLVVRHEPNIIGTTDVDSRPEFKDRKKTMKVDGVDDTGYFVSDFTLAEIKTLRAIQPLPERDQSFNGKFEIPTFEEVIALAQKKSKETGRTIGIYPETKHPTYHRQLNLPIEDKLLAALDKAGWNNAEAPVIIQSFETANLKELRKKTKVTLSQLVDGGEIDYKTGDLLPDTKPYDWTVSGRNGSNLDLLTPEGLKEVATYADIIAPWKRYLVKSFSVNGTATDVNGDGKVSDADFNVKPNPKLFEDAHAAGLKVHTWTFRDEPYRLALDYKNSPEAELMQFFDLGLDGFFTDNCKSGVPARNKWVAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CRJ2</accession>
    <name>A0A8K1CRJ2_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000004">
        <property type="protein sequence ID" value="TMW67430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CRJ2"/>
    <dbReference type="OrthoDB" id="168100at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW67430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="220" mass="24186" checksum="5965D7033624AA1B" modified="2022-08-03" version="1">MMTGNKHKNGTICMFPGCEKPMRTQKFKNHFVKAHLREGEAYTIEHRRLYEVARAETFSDSESSSGRVLAISAAKYKPEGVATTRRTSLDVAKKTDDGQTSPQDVVEPLLPGLPTTAVAPVVTMPAAPSRPKRPASAMSPPDAANEQLAMDVPTATTVLTLVQRRFNELNDKMDQILLRQNELFYLFETHVRESAASSEEPAAKRVKETSSLETPPASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CSA9</accession>
    <name>A0A8K1CSA9_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Poli38472_006117</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CSA9"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000019">
        <property type="entry name" value="Nuclear poly(A) polymerase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000027">
        <property type="entry name" value="Poly(A) polymerase PAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="18">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="17">
        <location>
            <begin position="214"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="16">
        <location>
            <begin position="360"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="16">
        <location>
            <begin position="423"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="529"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="107"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="240"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TMW68649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="659" mass="73476" checksum="B211BABB4D3AEE3A" modified="2022-08-03" version="1">MQNTQFAVAPHVLEQAYKAIRTTPPEPKDLEQSDKLQTYMDKHFATESDENIQRRSLILADLRATFREWVKQVCLAKGVPEEIAADAGGQILVSGSYRLGVNEPGADIDTICVAPRHVTREDFFSTLKDIFLKHPKVTNLVAIEGAIVPILTFDYEEINIDLQIAILPRNTIPDNLNILDDNILAGVDTATEKSLNGPRVTELMIKLTPNRESFIGVLRVVRRWAKRRGLYSNKMGYLGGVNWCILVCFVNQLYPTAAPSTLLLRFFMVLSTWKWPLAIQLCKTYDAKLGLEVWNANSGNNRYHVMPILTPAYPSMNSSFNVSTHSLSVMKDEFKRGLDLVQDILGKGGDDWDALFEPSDFFAVQQHYLAVDVYTTKEDEEQAWCGFCESRIRKLVDSLAYIPQLCRIRAFPKKFPLSYADDGAAAGATKKYGVCYFVAFDVDRRKLMGKEVSIDNSVHYFTQNDLYRWNKRTATMDVTVTPTVWKNLPESVFEDMGGRAVARNVRKEFMRKKKEEELAAESTAASLLAEHGSDESQNVFSQDMSEDMSVTNSRPPSPNPANESDTSLESQRDRSASIGSTKDQSSDKPASQGDASTTEVKKASPQATPQNAKLPAGGPASASSTPVKSARDLDKRTPAPAVASPRKRRKMKITFAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CT87</accession>
    <name>A0A8K1CT87_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_005820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CT87"/>
    <dbReference type="OrthoDB" id="78107at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050498">
        <property type="entry name" value="Ycf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="30"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="390"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="424"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW68352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="489" mass="55573" checksum="C4A6AD346C176EB6" modified="2022-08-03" version="1">MQVDRRTKGFQLGLDSKTVVLDPITKKHYRVLIVDPDLQRREDLADGLEHYFEILVAATNERAFTLLGMFTVDFVLLRLTLGNDHSIASSPSLEFIREIKRKYFHTPVSLMVGHSTENDKLLSQALNLGACGFFDDSLTTEMLIERMSKLLHSLVLAQREVYQCRGGSDLLKDDKDAEGTHSVQAIMKRGTMTNLTKRPATSKPASVTYDQEKMLMELSIKQHKQCHVRRQQLTETLAHSHSVLGLGLDVQSSNEQVLSPVLAALQSPSLLHSMSAPLTTTARTLGSICKKIPPLPSQKEISNQIYARPHEIQQRIHKHLYERYHATTHDAVPQDPLLRPCVAVDPESISRSARNLLVGKAYRLYLEKRYEEALQQCDRAIRMQDNNLVKLAYLLRGVLYDLTGNHMRAEREFLTSLKLDPHLHQAHFNLSVCHLRIGKDHQALQDVTTALHMDPTNRDYLSNRGLIYRRLGEFGLAQNEYNKLSHVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTG2</accession>
    <name>A0A8K1CTG2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Coiled-coil domain-containing protein 103</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_005843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Dynein-attachment factor required for cilia motility.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium</location>
            <location evidence="2">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DNAAF19/PR46b family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTG2"/>
    <dbReference type="OrthoDB" id="447931at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007368">
        <property type="term" value="P:determination of left/right symmetry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003351">
        <property type="term" value="P:epithelial cilium movement involved in extracellular fluid movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042422">
        <property type="entry name" value="CC103"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031733">
        <property type="entry name" value="Dynein_attach_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025986">
        <property type="entry name" value="RPAP3-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28572">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28572:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15867">
        <property type="entry name" value="Dynein_attach_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13877">
        <property type="entry name" value="RPAP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein attachment factor N-terminal" evidence="12">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-polymerase II-associated protein 3-like C-terminal" evidence="11">
        <location>
            <begin position="109"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF15867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW68375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27372" checksum="D365C8E1C74B235B" modified="2022-08-03" version="1">MTTPQTLASIEHGCFDTSALQEELVKALEDDRKYKRTDAMKKRAIHTAANYDEFRNLVACADLKPVKQKELQSFTKTERSNNLGYKKKTRKEYGASLKFSTQEAATDVPPATAVDFCRQWSRYLKSSDAKYRYLRLTSVEKLGTMFKGDLEADLLAEIAKVLLWSMNSTPDDTNSYNPDNTAAFALDTMAALSTTSRFSLILDFLDNNQIEVMRSLFSEIEKVVAKDETLVSKVHATGASYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTM0</accession>
    <name>A0A8K1CTM0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTM0"/>
    <dbReference type="OrthoDB" id="3231855at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052772">
        <property type="entry name" value="Endo/PolyKinase_Domain-Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535:SF1">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="454"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW68063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="531" mass="59957" checksum="367F9C910D76987A" modified="2022-08-03" version="1">MRTSPTHRPARPEDDAALWKLTQSDPEEICVDLVLDILAASQDETTTGGVTFTRDEVRHAIAQEQGDIDRAVNELMSLMAVRALQEENNQNEELPSEWRAATTLQWQELCSGLGLTECDSFFKVLESMPEEERDATLSADGGFFQQLLLTLDEEEAQPQVEGEGDDDDEHPLTRLQKLFPHTKMNVIEDVFESQGFDLNATAVALENIQSLDNVHSFASVIKANKSRSLVKSAEQAAMESRYSDAPSVTSLGHFPVLPAKSKQHKRNRRGPETNTSSHTGPWLNAWNTTHHGQTKETKLTTQLKLERLHRLLPTIDRDVIQTTFYLNGCSSNATEAALRQIFNLPVPENTGSASGNEPEEEEEEEGPVVRRSAYASDDNLSYEECRARVDNCWQNLSDRYCSALDSFNRNHRIIANDRVRDISRARQALREAQHEAAHAFVESHRFHIRQQRPLDLHGLTVLEALRVSREVVEICRAERIRRCLLIVGVGNHSINQKARLLSAIQLSLERRQISFRKESGMLVIFPLRSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1CTQ1</accession>
    <name>A0A8K1CTQ1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphomethylpyrimidine kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_005894</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000002">
        <property type="protein sequence ID" value="TMW68426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1CTQ1"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19368">
        <property type="entry name" value="TenA_C_AtTH2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000003">
        <property type="entry name" value="Phosphomethylpyrimidine kinase ThiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858:SF17">
        <property type="entry name" value="HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PHOSPHOMETHYLPYRIMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="5">
        <location>
            <begin position="16"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="6">
        <location>
            <begin position="378"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW68426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="69102" checksum="08C48B0E091F0592" modified="2022-08-03" version="1">MTTMLLPDSMARALWTQAELKAFQCLYHPFVVRLANGTLAKDEFQAFLLQDAYYLHGFAKAFAYAVTKCASPEHSLAIIRLMGGIEEELRTHSAFLQSFGIELFQVQETTVAPATRHYVDFLLSTAKNSSSVVEILTAMTPCMRLYSFIGKAIDAAAIKTLEGVENPYQRWINAYCTDEFEKAAEVTETLLDELAAFENVSYETLVPLYNRAMELELRFFEEYSPLARASPLSLHSYPLEIHVDLDDASWKDQEITPVLRVKAAMEWTLSSHERDLDALWNLPPGAYHVFIDRQDEAHLVSITSLSSPRSSTEYSPLLSVFAASQSVVNPVHTQKRAELVTFLKSLAASASFTWYSTPSSIAHAAHRVPRVLTIAGSDSGGGAGIQADIKTCTTLGVFSTTALTAVTVQNTHGVHGIHAIPLNDLADQITCVLDDIGTDVVKTGMLFNEEIIEKVATLLETRQLPLVVDPVMVATSGHRLLKAAAHESMVERLFPLATIITPNIPEASALLEDRVIDSVDAMHGAAQALAAFGSRFVLVKGGHLSDPPGNCVHDVLYDAERDEFHVIKNKKLKTRNTHGTGCTLAAAIAAYYAKSPDMVRAVKAAIAYLHGLLESSQSLTLGGGASGPMLHTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAB4</accession>
    <name>A0A8K1FAB4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_008733</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAB4"/>
    <dbReference type="OrthoDB" id="166391at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035419970" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="303"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="546"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW56085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="913" mass="97178" checksum="A3F951C414CDC812" modified="2022-08-03" version="1">MTHRLLRLAWTCVFFTVASASLVWLPDLSPSSSSSSSSSSASTSVSDAETIVFPSPSWLLNSGPVGILTDAQGVLRTVDGIVVPIAPRFAVTTPALLSPVGLEKLRLNHSLLVVFADESVRVSRVIYEPNDALIVLELASEPLFPVYTSIITAPPLEHVAFDDVQVAMFDSVLDTPAFDTERMMMNRIQEVVGTTSVTFKTESDCGLKDDSQICATISQLSTSLSAAHPRELEASPSTNAMILFYNQAIVGFSVASSAVDSTSRVFLRLGAPKHRAFLDDVTNQTTSWLEDDVFAIDEAFPSFLASFYTAGDVQVACQGVLIAPEFVLTTASCVNANPNITRVEFETQHAKFPQSVSSDQFIKHPGYEQGDTSLDTALLKLTEAITTIRPMVLNAGRVEQDTTFARLDVVTDKLFKGRNDRFVAETPVKGQPAHCNETNNSTVKARLTHMICLLPDVLPPSDDTGFDGVGAGSDGPVFASLITEKAVATTLIAKSKMAGLSLVGLGVTTESNADITGQVFVNVAKSANFINAYTTGQSWSVASMTSTGGDTLLPPDKRFVVGLRVTRDGQNYCGGALIAPTYVLTAAHCVTDGLANYVSIGSSESSGTRSEVIEVLHKSVRVHPKYGSGAKFSYDAAILEIAVASNANPVVLDNSQDFVNHEVATMYGYGVTNASSDELSPVVRVLQLPLWSKAGCAAELPDIDGCMLCAGGQRGVDACTGDSGGPLVLDVSGVSYLVGFVSAGYGCGMEDVPGIYTRVSSLYDFVNAYSVGSKWRGVPSSPTVTVAAPSPGGEVRSSDTPTTESGVISVGSDGFYPDAFAHADLKLSELSPLVRDALMSFLLSNENNSMLSASVLQSLAASDNLLRFYSTGELESLLKIIRNHNAKPLYARKDRFGRWLSHYAKTTDACRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAN4</accession>
    <name>A0A8K1FAN4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAN4"/>
    <dbReference type="OrthoDB" id="162872at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF6">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1078" mass="122142" checksum="5A4EDEFCF5912B4B" modified="2022-08-03" version="1">MDDHISDPCTQPSPPVVSFTSEQQLFIDLAVVTRRNLLLVAPAGYGKSFVIKEIVERFRHELTRIDEQPVYALCASTGKAASLIGGRTLHSYLGIGLAQGTPDEWVMCLRVNSSMRPKLEALKAVQVILVDEVSMVSAEFLDKISTYLQLLRHNYRPFGGVQMILIGDLCQLPPVKESFIFRSKEYKRGYFHPFQFTRCFRQNNREFVALLNEVRFGDCADREFATLQQRTSIDPQYSNGLTPMRIVSTNEEVDKINADEMEALLRKTGVAKERYTCYLSNPKHAEYAKKCREDARIPEFVDVAVGCQLVVTHNLTDKIVNGTQGRVIATAPNMIGLELDDGIRATIGYASFKDPEDPDVFKADALFSFMPVRLGYASTVHKAQGMTVKLLEIDFARFFAHGQAYTALSRVTDLQGLVVKNLTPEAFICDASGDPSQQANMTPPANGAKRVRRVRARVASTVDTTEHTEDAHAKEDVEAHSDVSAASSDDEDSPRKKPKGTKVYYDPVWGEVVLGKGIVTCKRCEQVIHRFGPQPKIKVVRNHFRETNTRHKCPFAREVTLVMDAKKQLRAHKPTRAEFAQRMGLFKRRMAQWIYASGHYFDEARDSFFRSGFNVFQPDVSLPTVYELETDLLELEFSACAGMVQRALNARLYCLCLERWTAPDGRSMTNYAASTDNQSYFLRTSQNDPKQRSESMVMEIKRVLTQQKYTTVVGVLTTEAHEISEASRVAIQKEYPECIFYYGCVAHALTRLLTDLCTALPWLERIHDTVHVLLKVVEENTSIRYQLHQLQDAESRPALVQVDELHGVMFYAALESVEKSRKALETLVSQEGFGIDDEELTLLKDVFSDESFKEDLSSAIQLLQPVHRELERVNTESLPLSYVYRCFLELSSFFSQTNLVDKKETPLLRACVTTRFHAILADCHKIAYILDPFYLASGMETHTRHQVDALISSLFKQSKLTAGIDMYDQLARYRAYVPELQSTSPSYHALLTSGGVSVSSFWSEHGQFFPELQQLARAVFSMPPANLTPRHRFAHVTTEVFDKFNGVLPEFRVHKLTYIRCNLKHMVPEEPNEVNTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FAW3</accession>
    <name>A0A8K1FAW3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Adenylate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010368</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FAW3"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036193">
        <property type="entry name" value="ADK_active_lid_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57774">
        <property type="entry name" value="Microbial and mitochondrial ADK, insert 'zinc finger' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="794"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="901"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="794"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="931"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="107907" checksum="F261AE56A91FE8DB" modified="2022-08-03" version="1">MPLTVRVCSEADQPAVDALAWPEPPERRRLFGITHTGALIDTCTLPLCVVDTATDQIVGFAAFDDKVPTSLLHWPEATEYLKKKLLFGRANGCILLSAFIQDASVAHDHVVTEIFHYLFATKPEVGGVVLAVPVGIDLQDLGLFHQAFSCYDSISLSSGALFRFFRAVRVDYTSCVYARPAQTTDLRILQSIVEKQQMEWRLQDAASYHAWFDANTLQQTLTRQDGHHACIVAHSVSSDAPTGLLSCSDAFSREQLDAYTRLFSELYRSSGHNELQTAQLDAGGSANTPAMVSPPRIVICGPTGAGKGTQCEYLVEEFNLVYISTGTMLRWHSEHGTALGLQAQAYIDAGELVPDELMLDMVIKRLNDDDCRTQGWVLDGFPRTEMQARVMLAQNVLPDIVVVLSLADDDVIQRLCGRRLDIDTGRIYHVDWDPPPEEVADRVVHRLDDREDHVRKRLQTYHEHVEAIFQVFMKTAKIIPTDGARNKQAIARKLIREVYYAKKMRRAFKLRHVPKLVISGPPAGGKGTQCEWIVQAFRVVHLSTGDMLRAAIQAHSSLGLEAKEYMEAGQLVPDDLIIDLILDRLEQPDCLKRGWLLDGFPRTKAQAEAMLAKGIFPDAMLLLDVPDEEIVRRISGRVLDPETGKTYHLSFNPPPPGDIAERCIQRSDDTVETVRVRLQTYHDNCDAVREAFEGAQCTITSADGTLPIERIAEEFFQTIETSLLHNNCFFIDMFAMELDYECRAQQFLIKAFKSFPDKDCLLLALPESCGRPVITTGFRAVRLDPTLSSVVRLQQRRGSNASTASPTVQQSSGRKSQTNKKTGATPIVPQRPSKQLVLYAFHRDELPFLNFSGSELLHVDDFDKPEDTEQVREAENLVAVKGLGVRGLTHVVRVWSARAWNGLTGGGGKSSPKAKTAESPRRKSFFGGGRAAPKASKTSKASNTSQSRVPAGQPTPSLGRSTPAPIAETVEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FBU6</accession>
    <name>A0A8K1FBU6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Poli38472_014932</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000134">
        <property type="protein sequence ID" value="TMW57645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FBU6"/>
    <dbReference type="OrthoDB" id="158706at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
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        <name evidence="3" type="ORF">Poli38472_010240</name>
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        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
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            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
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        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">ATCC 38472_TT</strain>
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        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW60766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="365" mass="42011" checksum="63C5FFC183E9532A" modified="2022-08-03" version="1">MKTPNPERTIVRTRNSAAMAATGVLHLVYPELSDEQRVFIRLDQEEQPLELREFSGKTRRRRRYKKHQGRETVAETKLFKYMVSQLPKAKYVYRVPISDTIRKHLDKAPSLPRRMLRPRKLTQIKRPAPEIAERVEKKLNRSFTVCPCYSCRHLHDVADPTFVCWYHGCGAKFPEFLDYLEHQLDAHGTISPHCRRIHRELHQQEGGVAPYPPISVYIGQQYLHPWVRPVEWTMDQVQVEQKALLKRLVVLRQSRQLPPGRATAIWAWFNIAFNEIQQCGPSQIRVHHRLALEHYESSLLLSAGARGAHDSLADVSIGRNWLTSPEYDNADRMLGLKRVGAPYAGDEASDDELVVLEESGASMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FFU0</accession>
    <name>A0A8K1FFU0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Golgi pH regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_009533</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000074">
        <property type="protein sequence ID" value="TMW62040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FFU0"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="155"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="297"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW62040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="56189" checksum="7E46B8084223B37B" modified="2022-08-03" version="1">MELLHGFLALPWDDCCMLLASYAAFFLFARFFFTWWLFQDYEVKASSTQLLFSLSFMFSFSIFQMVLFEVMEIMSVASRQWIWRVDLIAMTYLLVVILPLALFFTMAKEYGLPTRQAGVTALGLLTVYIYLFWRLGAVVEADLPPVSSSSVDALFSIRNFVSRVSLLGVVFMALLSGFGAVNCPYEYLSFFWRRIAEEDIEFLEKRLRHNLDILFAKKKRLHHETLVSARRRTAGGDGNGSGSSVFTRVFSLFKSKGIEDETYLKGLEAEIETLESLSRELFLEIHDMRDVQQRSRRAATLRGRIFNLFGYILSVFCVYKMFMSTINVVFRRNREKDPITDAIEKILYIWPSFALWINIRFISEVASLVFVGILVFTQTRGFLLTIVKFFRAWSSIVSSNSVVLWLAHLMGMYFVSSFVLMRMNLNPTHRRRIDEVLGDIEFNVFHRYFDMVFVMSASASVGALFLLKFSKASRTATDYGAQDKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGF4</accession>
    <name>A0A8K1FGF4_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Poli38472_012782</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGF4"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="7"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TMW61591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="787" mass="89429" checksum="5E647B9280738F3B" modified="2022-08-03" version="1">MRVEIDGLEVLFPYERMYSEQLQYMRELKRALDANGHCMLEMPTGTGKTVSLLSLVLAYKHAHPTAGKLIYCTRTVPEMAKCVEEIKHLMAYRAKYYGDQHKLTAVCLSSRRNMCVHPRVMAHADGEAVDAQCRKMTASWVRARANTGEHQDVELCSYYENYESRKSDENVLPPGIYSVDDLKELGIGKGWCPYFLTRYVVTYADVIVYNYQYMLDPKVSAMVSRAFEKESIVVFDEAHNIDNVCIEALSVELDRRSLDRASRNLTTISAQVNKMKQADKARLDAEYRRLVEGLRSSSAVVAPTYVNPANQQAIDTSNDILTANPVLPDDVLDEAIPGNIRRAEHFIAFMRRLIEYLRTRIRVRNVESETPQAFLHHLNQAIAMETKPMKFCYTRLNSLMRTLEITNLEEYNSLTDVADFATLVATYAEGFMLIIEPFDGVSGAHDPVLQLACLDASLAMRPVFERFSSVIITSGTLSPIDLYPRLLNFNPVIRESLPMSVYRSCICPLVITRGSDQMPVSTKFDLRDDLSVVRNYGTLLLEMASSCPDGMVCFFPSYLYMEKIIGQWDALGVLKRVVQHKLLFIETKDIVETTLALDNYKKACDCGRGAVFFSVARGKVAEGIDFDRHYGRCVILFGIPFQYTLSHKLRARLEYLRYTHQIREGDFLTFDALRQAAQCAGRVLRSKTDYGLVLFADSRYNRLDKRTKLPPWITQFLVDSHLNLSVDMAIFMAKKYLALMAQPVDEYTNVNSILLDTEGVQQWLGRHSIAKDKEDEPMPIASGNGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FGI6</accession>
    <name>A0A8K1FGI6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-tyrosine-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_010301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000111">
        <property type="protein sequence ID" value="TMW58742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FGI6"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008579">
        <property type="term" value="F:JUN kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="89"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW58742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21325" checksum="A5354C0BE11DA1A6" modified="2022-08-03" version="1">MARRSDDDVVEQLLARQRAHPSVDAVPIAAKIRDVSLFIGEAKAAQDAEFLQQHKIAHVVSLGTGRLSPASCDVLLVDILDMEDQLIVCHFNECIEFLRSALADGKSAVLVHCVYGQSRSAAVCVAYLMACKQMSMLEAYNAVQQARPCIYINLGFLSQLQLFERMEWDANLLGPTNAHAEQDNESIQVLCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FH89</accession>
    <name>A0A8K1FH89_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_000821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FH89"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000731">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000007">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000006">
        <property type="entry name" value="Lysosomal beta glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035452793" description="beta-glucosidase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="8">
        <location>
            <begin position="672"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW60779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="790" mass="86104" checksum="5C76CCD4A336BA9C" modified="2022-08-03" version="1">MLKTWVKAICCTALAMAIVPRGALGESADDRAKKIVDSFSVDQVLGQMTQINLDVILDSQGHLNEDKVRELAKLHVGSYLGGQYMNGAKNGTYANTVDEWRKMITRIQEIHTEVDNGNPVIYGIDSVHGAIFVQNATIFGQQINGGASFNPDLVRKMGEITGRDTAAAGIPWIFGPILEISQNPLWARTFETFGEDPYLVSVMGSNIIKGIQANKDVAACMKHFVGYSKTPTGHDRDGVTLSDFDLLNYFMPPFIAATQAGVKSAMENYISINGVPVVASSKILRDLLRRDLGFEGFVVTDYAEINNLYNFHRVAKSLSEAVRMSLTQTSIDMSMVPSNTDFINYGKEMLKDFPEYSERLKESARRIVKTKIELGLYETPVPGAKYVKDVGSSDHNQVALDLARESIVLLKNQDNVLPLSTSDSVFLTGHSADDRGNLCGGWTLRWQGYSGNSMFPNGISVKDGFQKLASNSSVSYFNGLSANGTYSAGDLAKAKELASKAKYTVAVIGEATYAEKPGDIDDLALPIGQINYVKELASTGTKVIVVLVGGRPRLLSGLPSNVHAVINALLPGELGGQAIAEIIYGKVNPSGRLPITYPKDPANIMIPYNRRVTTLCADQTPCKMEWDFGTGLSYTTFSYSAVKLSKTKVSGKNDKVKASVTVTNTGKVKGKETVMLFLIQPFRSISVPEAKQLKKFEKIELAPGKSKTVEFELNYKDWSVFDPQIGKGFVRSAEDGDFVVAIKPETDCDVYNSAGITNPLCAKFTLESSWVPFRLNAPEQTGISIASETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHD0</accession>
    <name>A0A8K1FHD0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_004681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHD0"/>
    <dbReference type="OrthoDB" id="26371at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000115">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000009">
        <property type="entry name" value="TBC1 domain family member 22A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000004">
        <property type="entry name" value="TBC1 domain family, member 22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF26">
        <property type="entry name" value="LD44506P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="186"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW59612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="483" mass="54768" checksum="44DEE7FC9F349C1D" modified="2022-08-03" version="1">MSSTADVPAPDESNPTHGSSNPFRNALHKFQKKKKEKASLGGSATSGFFSRGSRGKSSQNQPLPGSVKQVCAGQLPPVWATPPAAPPRKMSSPTVGSVKSPRMKTASLGSDHTEEIVAALEDASISSKPTETTNAETAPTSAPTPSAPPRSSSRNAAGNHRCEQFNQVLRNENVDLDKLRELSWGGIPYDHRPTAWRLLLGYMPSKQDRREAMLQRKRQEYKELLQQYYYIPDTDRGSKEQGTLRQILVDIPRTNADVRLFQDERIHQCMERVLYTWAIRHPASGYVQGINDLLTPFLVVFLTEFMDDPPTGDLSIVSDERLETIEADSYWCLTKLLDGIQDHYTFAQPGLQRMVQRMEELVHRCDVDLFKHIVERENVQFVQFAFRWMNCLLMREVPLTAIIRIWDTYLCEDNGFESFHVYVCAAILMTFGEKLKTLEFQDLVLFLQHLPTKDWSEDEIDPLLSRAFILQTYFADSPSHLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHU6</accession>
    <name>A0A8K1FHU6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_007258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000110">
        <property type="protein sequence ID" value="TMW59113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHU6"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF286">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="138" mass="14499" checksum="B9EA1D7C19EBE1C3" modified="2022-08-03" version="1">MATVNTLKRVVLVTGGNTGIGLAACKHLIQRDNTHVLLTGRNQERVNAAVEQIRPAAAATSSVEGAVLDLGNLNQVRDYCDQLKKQDVTLDAIVCNAAIAIPTPDLTEQGYGLMSPSTTWVTSSWSTSCVTSPSASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FHZ5</accession>
    <name>A0A8K1FHZ5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_000314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000108">
        <property type="protein sequence ID" value="TMW60272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FHZ5"/>
    <dbReference type="OrthoDB" id="10254700at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001508">
        <property type="entry name" value="Small GTP-binding protein Rab28, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW60272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="225" mass="25382" checksum="41D2F3A9513990F0" modified="2022-08-03" version="1">MSKETDSEHEPIQLQYKVIILGDGAVGKTSIAMRHTEDNFSNTYKQTIGLDFFLKRLLLPGDAQVTLQIWDIGGQSIGGKMLKNYIFGAQAVLLVYDITNYESFQNLEDWYRLVRRTFDDDKMPYVGLVGNKTDLNHIRAVKAAKHKQFSEENDLKSFFVSAKTGDQVNATFRQIASELAGIVVSKAELEVETPVLKAQIVNHQQNDPDVKSPDIRAKTRQCSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FID9</accession>
    <name>A0A8K1FID9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_002662</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF6">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1191"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1253"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1337"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1376"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1419"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="239"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="11">
        <location>
            <begin position="330"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW63721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1459" mass="160924" checksum="54289228A256F70C" modified="2022-08-03" version="1">MAKGERAPTWTGKSIRQLSLHRRRANPLNWGYGLEHVPFLVLYAFSLYHCLLTIGEPYAQAIKELEEAGILLPGATPGEAVDDGLSGLAASTLSQGVVREDLGSRINYTEFLNQDEEGPPLPNPFLPAIVPLLYLLGTTTSHLLMVLLQVWSVRVLALVKYSSVQTLANATYVMVVPRSFKGKSSIIPLETGKDGKRFFMFQKHKYVAEEDDGDTGKGVVFVKLRAPTANPIKSYVTSTGFATEQEVTHQLELYGKNEFSIPQPKFLDMFKQQLLEPLTVFQIFSVCLYMLDEYWQYSLFTLAMIIMFEGVTVMGRLKNLQTLRGMGNEARDVYVYRKKSWVKIKSDFLVPGDIMSIKRETEGDNPDNTVPCDVLLLEGSAVMNEATLTGESVPQMKEAIGSKMSEQDLAEALDMKSGHKVHLLFGGTTIMQNENTGSASKEDENAHVILTRSKSQAGLKQHKIPCAPDRGCTAYVLRTGFSSSQGKLVRMIEYSSGKVTGSSWDAYGLVFLLMVFALLSSGYVLRHGIAQKGKITFELLLRCVLIITSVIPAELPMQTAMAVNSALLSLIKLSIFCTEPFRISLAGKVDICLFDKTGTLTTDQLTAVGVVCEDLTSATKTVPSDKVLPHVPMIASNIHASLVLAGCQSLVQIDGKMVGDPVEEASIRAIDFTFDAATKRCQVKQDSERATERRWGSSIQQKDVYVQILHRNHFASKLQRMSVIAKVNLGERGQRYRSLVKGSPEAVAALMRTNALPEWYWPTYQSLARRGMRVLALAYKDLEGKPSDQEIAQKPRSWAESELEFAGFAVFQCLVRKDSNEIITKLRESSHRVSMITGDATLTAVHVSKEVNIIDRPALILTEKDADDASKGLVWTRAEDDAVFVEYKSKDITVLVKKYDLCVNGKTLVAAGEIDDGIWSNLASIRVFARMTPELKEKVLTCLKKVGHHTLMCGDGGNDVGALKQAHIGVALLGGFGSANADKSITGASKFTKKQATATAAVSRTDLMKLHVSVLKKRLAQKNADFSSCKEKKDYVDLILKTEQPAESEEAKRKKQQQMLVAAGKKPNYQQMSKEERAEYMKKKQEEIEADVRAREARGESFARVKAIAAFAKKEAEANRKERTGAKGFANFASNQAMSQYMDDFEDGEVPMVKLGDASIASPFTSRAPSIKGCVDIIRQGRCALVTTMQMYQILAVNCLISSYSLSVLYLDKVKYANSQLMALGMISTVASITLSRATPLDTLSPVRPLTSIFHPALFSSLVGQFALHLGCMIYLTELAKEYTPTGDVAHSKPGEFKPNVMSTVIFLINGVQTVSVCAVNYKGRPFMKSMTENPGLLYSLGLSIVGVFLLCTEAMPLFNKVLQIVPMPDPRFARILTGMLTLDVLGAFVWDQLCLLVFAPKIFIASYKSMTLKDLRQLIKMAVVSLIIIYVVANIDYDEIERQQKLLEEQAAATAASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIK6</accession>
    <name>A0A8K1FIK6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_004917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000109">
        <property type="protein sequence ID" value="TMW59848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIK6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW59848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="362" mass="41435" checksum="09F9EEE37E464A44" modified="2022-08-03" version="1">MMASTMAYGASSTNAEAVEKKPWRNRAKEEVKELQHTVKQLKATLKRLRERNKREKRVVHPSRVWEDVSQRQKRQRCRAEEENAKLRSEIIARAFLLQQMTQLVRQTGDSYLTFPTALYPRVPRPLLYTRSVEGYLARISELYYETESAFASHMTVDQIDTFREVSVAEEDKNTTLVTQKVCWTVPFTVERVVEALWQSMLLKPAPRGCGFDYNPALEASVLVASCCKSVIGPDSPKSVDVLSNLVIKKFPQSDRNGALMVAHMSAGLAESSSHLLKDGVGWDDYWLRVRECPREPHEESTSPLSQIQVFRRTRLKLVKNRTAAQRRFAGALTALIIDHVEEELEWRQQAIEHFLLASGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FIZ1</accession>
    <name>A0A8K1FIZ1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_008162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FIZ1"/>
    <dbReference type="OrthoDB" id="200110at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38019">
        <property type="entry name" value="KDA ANTIGEN P200, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38019:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="413"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW65520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="665" mass="78191" checksum="7FE55A80FBEBC2C7" modified="2022-08-03" version="1">MSSVDEGPASLALDGVHSHSSTMDSSSKKTKSKKRKGGRAQTIEEVFATISTVRSAGLNPPPEHIVLTPRSAEACLRCGVNPETLKIRDLESFYEAEITPAVQRMRHEAYSMRRHEEMKAVRTEKKKILADEDSAGPLTKRGSPNSSSPMANSPSPKGTSKAGFSGSLTPEKEPLSLVEIEQRRLEKVKRRQERELEQMLEFEMKMTKIQQEANEKIERERRQAEQRERERLRYAQEIAEEKRQREIKKKAQMDAEEERRRLVAAEMAAKDRELAEQKAKQERLRRIEARQREEERKQKAEEHRQQTEQIMKQQQQEIEERLEQLELAERARNEMLEEQRQERNVQMEERRRRVLLRIRKNLKQARKVELKRKREFQRKQDASEQLRREHEEGLARQRELQHQEQELMERKRRMVLEETRRDEERRKELLLQRQREIEANVQHVQMTQQQQLDLKKEYRRIQQQLKLDKVERMKRVQEYKRLETLRKLQETEERTQNMLQQKEDLVRRRKQLSIQSKIQRDLIMRTMENVKITKKWSQASKTIEKVMGKSPNASPSPTKSVKERPKSSSSVVGSRGTSLPSINRPITPSSASATGQQSRAFRPPSPPPTRTAFKYTKEAQEAATRKGRNLDDDERGPQSYNSPYDQVPVQIRPKKAAKQLRPAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FJL1</accession>
    <name>A0A8K1FJL1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_002180</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FJL1"/>
    <dbReference type="OrthoDB" id="167058at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="59"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="11">
        <location>
            <begin position="205"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="810"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="682"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="737"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="682"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="744"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW63239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="1091" mass="122354" checksum="8BACDF083DF8EB8F" modified="2022-08-03" version="1">MSHADATEDKTMPPIKTLGIAPLSLASTASSMSSGPRSSTLLSRRSGGRITPVETSASFVIMSGYLRMRVAATEWRMKTWYCLLYRAQLYWYASQRDAARAQKLQGRVSLVNAQVSDGIGKLHVYKHAFTFETDRGEVFFCAAPTEDEQSQWIEQINAAVVQSENEGSLDSSHSTHCVNGEECVPVCDAAPLTMEEAIKRATASFSSATSCFACGIAFGLLRRHRRQCFSCHHAFCRLHCSSYAVVGSGATTTHTSPARSQCPRICDQCSYRQHFITFVSMFTSRAVRLLRHDLVKVKHIPFSIDDESRHAKMRRELATVVRNPASFTALNVLCLLKKYIDVPWMFTRTLCMLIPVFERDRASLDEYWVQILGLFLPLLRATEPFSTSMQFFLRFVFAVCRRSNAFALRTMWECLAFYEDARVRGDRMTMSYLMLLVYASSAFDGNSAFVLDKLLKDAPAVQKTAMVQSMNEFLEIRVALRDDISETLPALWFNAMCEQKMTHCRQLVLEILEVLTDVDELLTMFDPSNTEALANLLTMRPEAEFSVEECLQACDHSAEEEDAWMTAKERAFDTQAAFVERLTQISDELRQVSPVESRGEALCDLLCELQQQFIAATVTESAIANPDTCSLRIPLSTQPIGEVELEELAVLRVLPNEGKVFSTRSRAPTLIVFEAATSAKPAEKPPAKILRRESSMQETDSDRDSMEGIKTRPGRAGSRAVLGRQESQMLDAMLCGLDEDDTGSSVPESSPLSSVENSQDGDLSIASEDAAPPDNLLVEEARDYYLESAAASFRSTHFTTDGNTSMQKSWERQCNAIRATSNFRDLPGWTLVSVIAKSHDDLRQEVFAMQLMRNLLDIFQSNGLERLYLRPYRILCTGANVGLIETLTDALSIDAIKKQFGSLAERYGTNDITPVFEGARDAFIRSMAASSLYCYLFQIKDRHNGNIMLDESGHVLHIDFGFMMGIAPGGAFSLEDAPFKLTMEMVDLMGGVTSSGFRDFKQLFLEGFLAVRREYINLVALIHLTAEDSPFPCFQQQTPATVLQAFRRRLFLHDSDDSARARILRLVDKSYNHWGTRQYDKFQYASNGIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKB6</accession>
    <name>A0A8K1FKB6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heat shock protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_012764</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000076">
        <property type="protein sequence ID" value="TMW61573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKB6"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000003">
        <property type="entry name" value="Heat shock protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000001">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="624"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW61573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="648" mass="69630" checksum="CFDB57DB07152217" modified="2022-08-03" version="1">MLSSVVRKSAPLAASKRMLSTATATEVIGIDLGTTNSCVAVMEGKAPRVIENAEGARTTPSVVAILDNDERLVGMPAKRQAVTNPENTFYAVKRLIGRKFSDKETQEVSKVVSYKIVAGPNGKDAWVEAKGRKYSPSQIGSMVLTKMKETADSFLGKSISQAVVTVPAYFNDSQRQATKDAGKIAGLDVLRIINEPTAAALAYGLDKADGKVIAVFDLGGGTFDVSILEISGGVFEVKATNGDTLLGGEDFDEELLRYLVAEFKKETSIDLSGDNLAMQRLREAAEKAKRELDGLAQTDISLPFITADATGPKHLNMKITRATFEQLVSKLIERTMTPCKKCLKDAGLEKKDVNEVILVGGMSRMPKVQTSVEEFFGKKPSKGVNPDEVVAMGAAIQGGVLRGDVKDILLLDVTPLSLGIETLGGVFTKLIPRNTTIPTKKSQVFSTAADSQTQVGIKVLQGEREMAADNKLLGNFDLVGIPPAPRGVPQIEVTFDIDANGIVNVGARDKATGKEQNIVIQSSGGLSDADIERMVQEAELNAEADQKRKALIEAKNEADSVAYGVEKTLKEHEDKIDQETAEQVKTALQNLRTQAEGEDADAIKAGIDEVQKLSMKIGEAVYKSQQGGAGEENKDENVHDAEFKDKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FKZ9</accession>
    <name>A0A8K1FKZ9_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_011604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000039">
        <property type="protein sequence ID" value="TMW64724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FKZ9"/>
    <dbReference type="OrthoDB" id="79001at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW64724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="208" mass="23224" checksum="FDC740F2E70D3264" modified="2022-08-03" version="1">MVGFLRKNKSNKTMLSSETALDRKGRVDGSSLLDDNGDPTEGTLFQQNLLAQKRRANNEEEDAPQNFPAPPTYPPQNYPYGQTYPPQQGYGYPQQQPQQTLPPMNTGFGNGRGSFGNNSSAPSYPTQNQQYPKQYGASQQYGAPQQQYGAPQQYGQQQFGAPQQYGQQQYGQQQYPVQYGNYPPPYPAQPDLGKKKSFFSIPGYGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLH1</accession>
    <name>A0A8K1FLH1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_002768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000072">
        <property type="protein sequence ID" value="TMW63827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLH1"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000037">
        <property type="entry name" value="DnaJ heat shock protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000015">
        <property type="entry name" value="Heat shock protein 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000106">
        <property type="entry name" value="Putative heat shock protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW63827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="307" mass="34714" checksum="ED247B31914BECE7" modified="2022-08-03" version="1">MDYYEILDVPRHASEQEIKKAYRKLAMKWHPDKNKHNPMEAQHKFHEVSEAYDVLSDPQKRATYDQYGYDGLKNGVPDENGETRDGYAFNERASEELFTKFFGTDNPFYDFGFGDTLPFASGLRKKGPEKAEAIVKDLECTLEELFSGVTKTVSIDRMRLQNDELVQETKTFQIKIKPGWKAGTKITFEREGSETRTHEAGDVVFEVVQAKHSQYSRDGSTLVYMAKIKLSEALGDHCVQVPTLDGRKLAISCNEVINPSAEKVIKGEGMPIASQPGTRGDLLLKFDIQFPKHLTSLQKQALVKILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FLK0</accession>
    <name>A0A8K1FLK0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">AGC protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Poli38472_007981</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FLK0"/>
    <dbReference type="OrthoDB" id="64015at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="77"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="405"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="676"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="774"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="782"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TMW65339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="95969" checksum="747583F17156937B" modified="2022-08-03" version="1">MAHVLGFHTPRVSTNTGSGGRGISARRKSVGSASMLGSMPPGPPSLASTASTRSSSNGNTAMATPNLIDLKSITAEEVEWEGYLYKQRKLVKNWTPRYITLQNRTITVYKSKTHAIAKEPDRGKWVVHQILTTLPSTGFGASKLQPDQLGFSFLATNGHMIHFIATSKIQKAMWLHMMRTSLQRASAETASMLPAPSMTPSFSLSRSVDEMRNTESTITKQLADKFLADIMELLSISPVEAVTDRLPEVLRQLSKDVELWFDLETAEAAQPSCVFKGVFHGREGFVQFVSLYVTKYLLAKDLSGETVHRAEDDDHHGYARMHNLINTVSGSTTLGKLALQLSFTPAKRLSRVVLAFRQRSSSSSSSTPKTRKSVQSNPIAMSEHASCFYQAYLSKRSLALSFSDFDVVGVLGQGGFGTVVLVKRHMSQDEYFAIKIIDKHSGAESALKERRILSGVRHPFLACLRFAFQTQTKLYLGLDYYKGGNLYLHMHTSKMDPTVSISSGRRFSVERAQFYAAELAIALSYLHSHGIIYRDLKPDNIMLDRFGHIRLVDFGISKQLRLDTEVGNGMYAPTGTLAGSPAYIAPEQLLTQKPQYGMEADWWSYGVLLYEMLTGSTPFHDANISQMYKKIQTAEVNYDRRPPIDEVGVDLLKKLLVRDPAERIGFSEIMAHPFFESIDWAKLEKKDVEAPFIPPADELMQNVHDHFRNMKVEESIGEMEIKNGKKQSMLNTKDESHFDEFSFAYDTSRDTFEGLSMADDGWLMRQLKEGAKMRGRLQSSADEVDSYNDDQASEDEGSGHHILKTQSSSSNSEDEGAEQPVLKSQISLGNSEDEGAEQPVLKTQSSNSDAEEVPANGSGSEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMH0</accession>
    <name>A0A8K1FMH0_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_007908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000003">
        <property type="protein sequence ID" value="TMW68236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMH0"/>
    <dbReference type="OrthoDB" id="79772at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044661">
        <property type="entry name" value="MED15a/b/c-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137:SF4">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="693"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW68236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="79979" checksum="0D86C8C902C78A9F" modified="2022-08-03" version="1">MSMPMSMSVPMAMPNANGAAHSSGGPAGGVQMGMGMNPMAPQYGVGVGVGVGVGVPPQQQMMMGMNSMNGMAMNPMMKMPMNTTGAPMNPMNPGIQVAGQPMAGADWRIQVTREHRANLIAKIYNELVRVSSEPPPGIKLWMNVAWYELQLYKESRTQEDYISKIFNRLKTLRAQQTDMNAAMNAQSLPNNGLLSRLDFSYYNNMNPRATPAQVMTSGQPQPGYPSHQQFPGHPGALPQSKPMVSGPGMANPAASGAMKDNLTPRGGMPGGTPLKPEGAITSVADNAAEYWRQHAALKSKYHEDVEKVHSAFKKYVDHMKDQNETEQKKKLRYLLSYVQLCASVLSEDKSTHQPRKLEELDKVYKYIVKIVNPYLKKLRTETDKRTFGPTVGTPGSSGTPGSSGLPQGSVIPPSGAMQQSSQQQAGASVAQQQQQQQQQQQQQQQQQQQQQQQQQQKNQQQALQNQASQQAQQQQAAQQNVQKHQQYQQQLQQQRHQQLQQQQQQRLQMARQQQQQMQFQRQQQQQAMQQQQQQQQQAMQQQHQQAMQHQQQSLQQQAMQQKSGGAQPPSGQSNDAKQQQPGKPTQASPGQQGNSAGSGQAQNQQQLRQQQLQKNAQVQAPPRGSNSPSLGSGLGLTLDDPSLYSGMDSSLLQMPSNLASSGSSSNFSMSFGNDLSPTTFSGSMDLGMLDIDGSGLSSLSYDGQDGSGTQGGGSGGAGGDSNGDSGDLMNFVEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FMJ0</accession>
    <name>A0A8K1FMJ0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_001576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FMJ0"/>
    <dbReference type="OrthoDB" id="166246at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW69420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="151" mass="17079" checksum="C802057A56FF4574" modified="2022-08-03" version="1">MHQPLRTLEFAPPCKQLAIIQIIVYVLSFSLTWYKVWWDSIIGLVVAFIGYWGFRDPITNPTQRSVRNFYYGSIASELSHAIALSVVLYYKLNAFLANDVIGLRVAHVHDVPGWTFVGFLITFLVVELTLTAGAIFRSNQLLAELARNSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FML1</accession>
    <name>A0A8K1FML1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Poli38472_004154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000036">
        <property type="protein sequence ID" value="TMW66389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FML1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046621">
        <property type="term" value="P:negative regulation of organ growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033276">
        <property type="entry name" value="BB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46400:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46400">
        <property type="entry name" value="RING/U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="381"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TMW66389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="428" mass="47467" checksum="564219903A3BD983" modified="2022-08-03" version="1">MMTRRDAEHVDRLEERLHALEQAYESERVQRDQLEKKYARLKRRYIRLERAHAQMLHDSHGMMNSVGHASPRARAPSPALSVASSSSTTTTRRSSVETRESPSLVIDLTSPTAQSSTRRSSGSLALDRAMRRSAEFQLPLSSEDFCGESPGSASDHTPSRPSTRSTRRFLESPSSAETTVSVSVTSSPNPRVGSTRRRQLDFHPDPLARPRPRLGVLNSPERSTRVTLRNTPSPALSLRSGESEEQTEVIFTPSASSPGSSVVASSPASGSIDSDEAASIALAQYLQQQENLAAMQEYEERIREANAHAHAHHHQPRDIAPTSFLNRGNVDPDSMTYEELLQLGEQVGDVKKERWRQVAVQVLSSLPTHRWNSRNESDISCIVCQYNFAPGDVALTLPCAHIFHEECVSGWVRENNSCPLCKLEIADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNA0</accession>
    <name>A0A8K1FNA0_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNA0"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="140" mass="15508" checksum="5C1DA0162F2A0AEF" modified="2022-08-03" version="1">MGRGGGGNVPVGGTVDISQWKAYFTEAFSRDHEAAHKSKPTEDACRNDQAGFIQCLNSNTNSVTNCQPMIDALQECRKNQPGSKSKKTLAFETPSGKATEQLNAYQVGLLEFFECVNDNARDIMNCQERMDALRQSQKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FNH6</accession>
    <name>A0A8K1FNH6_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Poli38472_012450</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. cNMP phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000005">
        <property type="protein sequence ID" value="TMW67334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FNH6"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07738">
        <property type="entry name" value="DdPDE5-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000029">
        <property type="entry name" value="Cyclic nucleotide-binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="489"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="717"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TMW67334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="828" mass="92469" checksum="9A2222C4D87FA418" modified="2022-08-03" version="1">MSDDAAQQESSVLETLKLPRGGVVTSTCIGPVQLGMPPETIKDSMKLGIPVPRHYIVPSEPFTRVLGANMGVNVAEFEFPAYCNFFFKRQCVNLIVTSLDVEKRIRQVFQETLFGPATLDLTHDFPHSTPPERVPDLQKELDYFRKFGDTLITLDMLLKFTHFNDQNEAVVVQGDQEITIRKNEGSFTIVDGRKSVTLADSVELPPPPAMDQIQDAFYPPAFGVTVLGSSHGFDPHGKTSGYVLWINHRGIMIDPPPFSSSILMANNIPALMIDGVILTHCHADHDAGTFQKILQEGRVALITTNTIYRSFLRKYSALSGFDPDFLKRVLDHRLVRVNDPTTIRGAEFRFFYSLHSIPCVGFEVKYGDKRIVFSGDTLNDVDRIKQLHEDGVLSTHRYEELLNFPWSCDAILHEAGVPPIHTPLKTLMNLDEDIRKRIYVVHTAAKDISPESGLRGAPEGVHSTITLETKPPENSGALEILDLVRKIDLFAELTLNNAFEILQMARKATYAKGSIVRNIGDTGDMFYIIILGEAQALYRQESNASSVTACEEEEVASHKTNSPRQETTAHSPVRASLTRKRVSMLSLAKNYFPGDYFDLQSLLTPNWTLPYQMVAVTKLSLLEFDAVDFNWFLRHTPAFSRIQRLAQSRLNFSYHIVEANQVFRRITTAQRTHLEIILNQREVSEGQILWDAGDKCSVAVIIDKGQFTLKHPKAPGTPTTSVVPRPASPSTSIPLVNRKHRGSGNRIMPLDMCVAMAKPDAENETPLSHGCFVGDVDKLILSEDTTHNTTLMCNSAGSIFVINKHDLQAFLLENPGILMSLSGKLYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FPI6</accession>
    <name>A0A8K1FPI6_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_008310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000037">
        <property type="protein sequence ID" value="TMW65668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FPI6"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW65668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="399" mass="43088" checksum="05D0D0EF8FDEE383" modified="2022-08-03" version="1">MVKFFQCYQRNGCITSEASSTEDPLAAFIVISDAFQNVGVSTSSWDVFQVRPPQFTFTSGTPRPIDVDRGSNYQQFVHSLGAMLAESAQDVRIRAVELPADPSQYYIPLEVTYYNFVGIAPTIYGSRADGNGLRGGDIMLRTLTGAQSSTSVLAMMLRTYSTTRVLSGLCAACGAALFGCDQSAIASGSCTFLQPGASSFTACLRQSSDLNFFLTQVAQRDVRKPLATQSCYDTSSSGATFKEDQWYKTSEALACFETAGCPFGPLHESIWDDNMVRISSNTITQNAYIPVNTFEASFRAMYVSRQLDSDPFDASATSEDLEALLMMVLPESAEVFASISPSGEGYTITVTYHLVFVPSLQLSVVVSDPSVNVQNSSPSTGLVVELSTVTTDPTTFAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQC1</accession>
    <name>A0A8K1FQC1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enhancer of rudimentary homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_001425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May have a role in the cell cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the E(R) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQC1"/>
    <dbReference type="OrthoDB" id="7887808at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY ERH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373:SF0">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016393">
        <property type="entry name" value="Enh_rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW69269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="106" mass="12278" checksum="C251EFE8BFE5DF90" modified="2022-08-03" version="1">MAEFRQAKHTIILVQYTRDPNSRTYLDFESVNAGMDGVVKMYEAKLKQLNPNIKNITYDIQDLYNYIDSLVDLSALVLDLETKTYLPCGKEWIKKKVFQVLKNQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQN1</accession>
    <name>A0A8K1FQN1_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Poli38472_001755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQN1"/>
    <dbReference type="OrthoDB" id="63453at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TMW69599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="254" mass="29218" checksum="B43F12F87B147783" modified="2022-08-03" version="1">MTAAAASSQRGRKFAGGRVTNLRESALVQQLHTVQAEVEALARRRDLMESMMLNAKVHAIQYAVQMTKQFYEIFSHGYNPAAHPMQSRQAEVFLRSLMTEDVMCTEFIGVDMFLRQYEIGALYHTSMSVALHDVSHVEHGDLAIHVKASAVARFRISRETLTRFFPSIIQDEQLTQQLIGQEYEMQYDKVFHFQNGRIFQHESRVDFCGGLMRMVGDPFLAMKLLQASIMTKHGHWKINNQIEEDRHELQNSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FQV5</accession>
    <name>A0A8K1FQV5_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Poli38472_012074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000006">
        <property type="protein sequence ID" value="TMW66958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FQV5"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035472553" evidence="2">
        <location>
            <begin position="19"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TMW66958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="378" mass="38140" checksum="685C502424D3A3AF" modified="2022-08-03" version="1">MKLFTPFLISVLLAIVSAQGFASNPQRTEKDRDDGALWEVENEALTDSEGFEPARLADDDVMFSAAQRIPAPPSAGTSTSVNTNPAAQVTPTEPNGAPAPVPIPIPVPAPVPSPVVTPTPTPTPTPKPTTVKPTPSPSTAKPKPIPASSKPSPTPASPKPTPAVTTKRPTPAATTAKPTNGAPSVKPTPKPGTSAPSKPTPRPTSTPKPTPARTTPKGSSGSSTPASPLPPRPSQPAPAGKPTPAPSQPVKDSPSPVPSGPKTPQESKPPTGPSSTSVTSSQPSTQVIPVTPCPSNTALTGTLTNPNAPVPFPTLDPTITPSPEVLPAAGGARPADVDVPGINITPLMTPSPGLDAQLKPSEPAPVDLSGIMSPNQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1FRW2</accession>
    <name>A0A8K1FRW2_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Poli38472_001563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000001">
        <property type="protein sequence ID" value="TMW69407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1FRW2"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="6">
        <location>
            <begin position="205"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TMW69407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="269" mass="30055" checksum="5F84C359AB947E91" modified="2022-08-03" version="1">MAAELKALRDYVVAHDGHEYDTLGEGLVALQITHSNLQTTMLDIRLDLHMTIEEVRFKVYRHCGTKPDAMDLFIVNSDGSPRFKLDDDRKMLGYYGVQSGMRLHVVDTDPFSLSRGGGLEDVSLIKKYEISEEDYDKREKTVRAYKRDQLAKDPNWKPKPMANAARAPVDPATVPGPETVEHMRVGDRCEVQPGGRRGQVQFIGEVPEIAAGYWVGVLFDEPVGKGTGTVKGKVYFPCEPKYGGFIRPHNVAVGEFPPEDPFADSDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2G1</accession>
    <name>A0A8K1C2G1_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_013116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2G1"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="160"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="520" mass="57617" checksum="9F4A5F310EFDF44E" modified="2022-08-03" version="1">MSSLAIGRPSTIEFDHVTYPGRRLWWPRRRTVTLELSLSHCAVVETHATKAHKAERTVLSWREVLGAQIQSPDGQRLQTPTDVVDVDGTYRFVLSALPAKISRPSEPKRRELAQWSFEFPGRIMSDAVALGRWVNFLADPRSTEEVMSKRALDEVVLNEKPARKFLVLINPVSGTGKSVQLYKDQVAPIFEYANVEAEVKLTERANHGVDIAKDVSLTAYDAIVTVGGDGSLCEIVQGLMARPDWHEAIQLPLGVIPSGSGNGLFGSLMHAHGEYFDTINAVFALAKGVAQSLDIAAVRNPFGDIMYSFLTSEWALVADVDVDSEKMRYLGVARFTVAALHHILLLRRIYEGTIWYLEDDPNAAYQPVPYKHEKGADRLGFDLFDKVEEGALASDGSSARWRKIDSGFHLVWVCNTTHPTTDSYMAPGAAIDDGYTYLVLLDGKHPRKDLINFLLSMDTGGHVDTESTQIIKSRAFRIEPANKDDVICVDGEVFRGPIETQVHHKVARVLTLPREAALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2N4</accession>
    <name>A0A8K1C2N4_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Poli38472_013250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2N4"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TMW55359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="109" mass="11705" checksum="B68B6C47CD298A50" modified="2022-08-03" version="1">MADASSKESSTESECYDEEEDVKDTQVKEEELHVQDVSNEPTLGSKSVVEASFPPSEFVSPFAALAQTPSLPAATTASRSENAQDATRLSKAELTTNIQALSAEHETLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C2Z3</accession>
    <name>A0A8K1C2Z3_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VWFD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Poli38472_013088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000148">
        <property type="protein sequence ID" value="TMW55197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C2Z3"/>
    <dbReference type="OrthoDB" id="155006at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035451543" description="VWFD domain-containing protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="3">
        <location>
            <begin position="147"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TMW55197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="562" mass="61507" checksum="51E1D2001FA7EDD6" modified="2022-08-03" version="1">MLSIKSLLQTTTMAAALLVACATAGTQPGTVKAAGGNLVEIEIKQFDDGAVAEALVTVTKEYFGRNPAFDVKVNIPGVKCEQDTFHVKKNCTKTGKQWVKCKPIGCPKKAKNGDVIDVPVTFEYTINDGTKREKETQVVKRCVKNCGSCSGQGDPHIITFDGVAYDLHKPGVYNYFESGPLKIQVFQDHCNTKPMPGSNDPPGCYKGVAIAYADSVARFYLENNSLKALKGSDALEWLDIKEMEGPTEAYRVFLKVDSDSYVDVTTGNWDDYMFVNVALHASSFLRREGAKGLMGNWNDNPDDDEKNPEKVAEMYKIDIADNLLTCSDCTKFLTEPGESDIPARNLSTPLDLYQQGYAPVTGLAKKEIKPVVTPLPGKSRRMAEDEYGAESKKADDDEYGAASKKEDDYGSDGQTNDGYASEKTTAPPATKAPVTEKPASADKAAKLCKQVLSSIPHCAEYVDHPQFYIDVCEKDVNALGRFCFVDITKLSYLRECRRTLDSLILSQTCAKDENSKIVAHRKELNFGDLTMCKDNCNGKGDCLAAGCKCQKGYTGFACEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C390</accession>
    <name>A0A8K1C390_PYTOL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Poli38472_010524</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C390"/>
    <dbReference type="OrthoDB" id="10051896at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035460260" description="Peptidase S1 domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="53"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TMW55642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="282" mass="28793" checksum="E449235B17873AAA" modified="2022-08-03" version="1">MKFAAIATAGALAVATASASDALSYPEFLVKSHMAAAVMKSAQEEGSVIKPLILGGTEVPAGQKLWTVGLRSSATGSNFCGGTLITPKHVLTAAHCYGGISYVSVGSRYLSGSKDGERIKVSKQTRHPNYSSRTSSNDFMILELATASKVSPIKLKTAGPAVDTTATVNGWGVTTQDGSQPTIQRQVDVPVVSDSACAKVLDITPATMLCAGGKSNKDSCQGDSGGPLTVKSGSEDVLVGVVSWGEGCGLAGYPGVYAQVSAAKSWIDTTLKSAGANATWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C3F7</accession>
    <name>A0A8K1C3F7_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Poli38472_010661</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000147">
        <property type="protein sequence ID" value="TMW55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C3F7"/>
    <dbReference type="OrthoDB" id="70202at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051598">
        <property type="entry name" value="TSUP/Inactive_protease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701:SF2">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN YJNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TMW55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="322" mass="33338" checksum="62B4B1F19AB3877D" modified="2022-08-03" version="1">MLARGLRQSAVTKSAAFGARRSAQPRVFCSASKPKSVKDASKLSLGVGIAAGGFAGTVSALTGVGGGLILIPVLAKFTTLTQQAVNGTSIGAVTVAASVGAYNHFESGACNFPLALLTTLPSVIFARYGVQTAHRLSSKRLSLVVGSAMLMCSPLIALKNSQYFPKWSDSVNPLDLQCFSRDVADQEVPYIERIKADVPGFVMANAKYVGAGCFAGFISGLCGLGGGILMTAYLTAASDLPQEVIIGTSLLSIVPTAASSTYFNVKAKSIHIPTAARVGGSLAVGVYLTSKYVTHQVPEDTLRKILATTLGAAAIVMMRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1C404</accession>
    <name>A0A8K1C404_PYTOL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Poli38472_008677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pythium oligandrum</name>
        <name type="common">Mycoparasitic fungus</name>
        <dbReference type="NCBI Taxonomy" id="41045"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Oomycota</taxon>
            <taxon>Peronosporomycetes</taxon>
            <taxon>Pythiales</taxon>
            <taxon>Pythiaceae</taxon>
            <taxon>Pythium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2019-03" db="EMBL/GenBank/DDBJ databases">
            <title>Long read genome sequence of the mycoparasitic Pythium oligandrum ATCC 38472 isolated from sugarbeet rhizosphere.</title>
            <authorList>
                <person name="Gaulin E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">ATCC 38472_TT</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="SPLM01000146">
        <property type="protein sequence ID" value="TMW56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1C404"/>
    <dbReference type="OrthoDB" id="10052040at2759"/>
    <dbReference type="Proteomes" id="UP000794436">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000038">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TMW56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000794436"/>
        </source>
    </evidence>
    <sequence length="547" ma
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